diff --git "a/PathMMU_TEST_local.tsv" "b/PathMMU_TEST_local.tsv" deleted file mode 100644--- "a/PathMMU_TEST_local.tsv" +++ /dev/null @@ -1,4471 +0,0 @@ -"index" "question" "A" "B" "C" "D" "answer" "category" "question_type" "image_path" -"0" "What is the inferred histological diagnosis based on the increased melanocytic activity and pigmentation?" "Basal cell carcinoma" "Acute inflammation" "Dermal nevus" "Melanocytic junctional activity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/0.jpg" -"1" "What can be inferred about the stromal compartment of this breast tissue sample?" "The stromal compartment is poorly demarcated from the ductal structures." "There is a significant infiltration of inflammatory cells." "The extracellular matrix shows extensive fibrosis and collagen deposition." "The connective tissue is well demarcated from the ductal structures with no significant inflammatory infiltrate." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1.jpg" -"2" "What is the predominant cytoplasmic staining characteristic observed in these cells?" "Clear cytoplasm" "Eosinophilic cytoplasm" "Basophilic cytoplasm" "Amphophilic cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2.jpg" -"3" "How would you describe the arrangement of the cells seen in this histological image?" "Organized, with well-defined architectural patterns" "Uniformly distributed with regular spacing" "Disorganized, with a lack of discernible architectural patterns" "Arranged in regularly repeating structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3.jpg" -"4" "What aspect of the cells' appearance in the image is a common histological characteristic of mesenchymal origin?" "Eosinophilic cytoplasm" "Intranuclear inclusions" "Mucin production" "Presence of lipid droplets" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4.jpg" -"5" "Which staining pattern is predominantly observed in the positively stained cells?" "Membrane staining" "Nuclear staining" "Cytoplasmic staining" "Extracellular matrix staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/5.jpg" -"6" "Based on the cellular morphology, what type of nuclear chromatin pattern can be observed?" "Hyperchromatic nuclei" "Pale and vesicular chromatin" "Evenly stained chromatin" "Finely dispersed chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/6.jpg" -"7" "How would you describe the amount of cytoplasm relative to the nuclei in these cells?" "Scant cytoplasm with a high nuclear to cytoplasmic ratio" "Scant to moderate cytoplasm with varying nuclear to cytoplasmic ratios" "Abundant cytoplasm with low nuclear to cytoplasmic ratio" "Moderate cytoplasm with a high nuclear to cytoplasmic ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/7.jpg" -"8" "What feature in the provided micrograph is indicative of chronic inflammation?" "Granuloma formation" "Multinucleated giant cells" "Neutrophilic infiltration" "Plasma cells with eccentrically placed nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/8.jpg" -"9" "The nuclear-to-cytoplasmic ratio seen in the cells within this image is:" "Decreased with barely visible nuclei" "Slightly increased with more prominent nuclei" "Significantly increased, with the nuclei occupying most of the cell volume" "Normal, with nuclei appropriately sized for the amount of cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/9.jpg" -"10" "What might the increased eosinophilic staining in the interstitial connective tissue imply?" "Normal spacing between muscle fibers" "Possible muscle fiber degeneration" "Decreased collagen deposition between muscle fibers" "Increased connective tissue indicative of muscle pathology" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/10.jpg" -"11" "What is the predominant chromatin pattern observed in the nuclei of the cells in the higher magnification inset?" "Fine chromatin without overt clumping" "Coarse chromatin with multiple nucleoli" "Prominently clumped chromatin" "Dispersed chromatin with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/11.jpg" -"12" "Based on the visible characteristics of the epithelial tissue in this image, what level of dysplasia can be inferred?" "No dysplasia" "Moderate dysplasia" "Mild dysplasia" "Severe dysplasia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/12.jpg" -"13" "When examining the connective tissue underlying the epithelium, what is the most appropriate observation related to the cell population?" "Absence of fibroblasts" "A high number of adipocytes" "A moderate number of inflammatory cells" "Sparsity of inflammatory cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/13.jpg" -"14" "Considering the description of the nuclei, what is the likely appearance of chromatin within the nuclei as seen in the image?" "Largely euchromatic with many areas transmitting light" "Homogeneously hyperchromatic" "Hyperchromatic with visible nucleoli" "Patchy with areas of clearing" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/14.jpg" -"15" "What is indicated by the presence of pink to reddish elongated and irregular structures interspersed among the adipose cells in this histology slide?" "Abundant collagen deposition" "Active fibroblast proliferation" "Increased density of vascular tissue" "Presence of inflammatory cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/15.jpg" -"16" "Based on the morphology of the cells seen in the image, which characteristic feature is consistent with mature adipocytes in this section of adipose tissue?" "Small cells with high nucleus to cytoplasm ratio" "Lots of cytoplasmic granules and a prominent nucleolus" "Large, empty-looking cells with a centrally located nucleus" "Large, white empty-looking cells with peripheral nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/16.jpg" -"17" "What does the high nucleus-to-cytoplasm ratio seen in the cells of this tissue suggest?" "Active protein synthesis" "Low mitotic activity" "Hypercellularity" "Quiescent cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/17.jpg" -"18" "In the tissue section shown, which area appears acellular with chondrocytes embedded within an extracellular matrix?" "Area labeled 'c'" "Top right region" "Bottom right region" "Area labeled 'd'" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/18.jpg" -"19" "The histological features of the tissue in the image suggest which type of inflammation?" "Chronic granulomatous inflammation" "Fibrotic inflammation" "Acute inflammation" "Serous inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/19.jpg" -"20" "What is the predominant cell shape observed in the provided microscopic image of the tissue?" "Columnar" "Spindle-shaped" "Spherical" "Cuboidal" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/20.jpg" -"21" "Which feature of the cells' nuclei is most apparent in this microscopic image?" "Round and centrally located" "Hyperchromatic" "Multilobed" "Elongated" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/21.jpg" -"22" "Based on the tissue architecture and cellular characteristics, which features appear to be absent or minimal in this microscopic field?" "Cytoplasmic abundance" "High cellularity" "Extracellular matrix" "Cellular pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/22.jpg" -"23" "Based on the appearance of the tissue architecture, how would you classify the differentiation of the cells?" "Moderately differentiated with some structural atypia" "Poorly differentiated with minimal structural resemblance to original tissue" "Well-differentiated with distinct glandular structures" "Undifferentiated with complete loss of normal tissue architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/23.jpg" -"24" "In assessing the arrangement of the epithelial cells in the image, how would you describe the pattern?" "The cells are evenly spaced and well-differentiated" "The cells exhibit multilayering with loss of polarity" "The cells are in a single uniform layer" "The cells form a stratified squamous epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/24.jpg" -"25" "Considering the stroma surrounding the epithelial structures in the image, which statement best describes its appearance?" "There is an abundance of stromal connective tissue" "The stroma is scant but appears supportive" "The stroma is dense with inflammatory cells" "The stroma shows extensive fibrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/25.jpg" -"26" "What can be inferred about the extracellular components in the image?" "Irregular bony spicules within the inflammatory infiltrate" "Extensive hyaline cartilage formation" "Abundant adipose tissue deposition" "Dense bundles of well-organized collagen fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/26.jpg" -"27" "Based on the intensity of staining in fields A and B, what can be inferred about the level of target protein expression in the corresponding cells?" "Field A shows higher protein expression than Field B" "Neither field shows any protein expression" "Field B shows higher protein expression than Field A" "Both fields show the same level of protein expression" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/27.jpg" -"28" "What can be deduced about the morphological characteristics of the cells in fields A and B?" "The cells have large, irregularly shaped outlines and variable nuclear sizes" "The cells are small and round with a high nucleus-to-cytoplasm ratio" "The cells are uniform in shape with dense, homogenous nuclei" "The cells are spindle-shaped with a small nucleus-to-cytoplasm ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/28.jpg" -"29" "Considering the cellular diversity in fields A and B, which type of cells can be speculated to predominate based on their morphology?" "Endothelial cells" "Syncytiotrophoblasts" "Mesenchymal stem cells" "Cytotrophoblasts" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/29.jpg" -"30" "What type of cells are indicated by the arrows in the image?" "Adipocytes" "Fibroblasts" "Plasmocytes" "Erythrocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/30.jpg" -"31" "Based on the staining characteristics and cell morphology, which cells present are responsible for the production of extracellular matrix components?" "Cells with multiple, small, dark-staining granules" "Cells with eccentrically placed nuclei and a perinuclear halo" "Smaller, spindle-shaped cells with elongated nuclei" "Large, pale-staining cells with abundant clear cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/31.jpg" -"32" "What does the morphology of the tissue surrounding the blood vessel suggest?" "Extravascular matrix with mature cells" "Dense connective tissue" "Hyaline cartilage" "Predominantly adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/32.jpg" -"33" "Based on the observed chromatin pattern in the hematopoietic cells indicated by the arrow, which description most accurately represents the observed cells?" "Cells with highly condensed chromatin and normal nuclear to cytoplasmic ratio" "Cells showing typical maturation with reticulated chromatin" "Cells with an open chromatin pattern and abnormal nuclear to cytoplasmic ratio" "Cells with hypergranularity and condensed chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/33.jpg" -"34" "Based on the tissue morphology, how would you describe the tumour cells which are present in the stroma?" "The spindle tumor cells exhibit nuclear pleomorphism and frequent mitotic figures" "The tumor cells are spindle-shaped with elongated nuclei and are distributed uniformly without atypia" "The tumor cells show high levels of hyperchromasia and atypia" "There is a high degree of cellular crowding and loss of polarity throughout the tumor cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/34.jpg" -"35" "What does the distribution and color of the stain in this tissue sample likely indicate?" "Localization of a specific antibody tagged with a chromogen" "Presence of glycogen within the cells" "Deposition of hemosiderin due to hemorrhage" "Accumulation of lipofuscin pigment in the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/35.jpg" -"36" "What can be inferred about the stroma in this image?" "The stroma appears acellular with abundant extracellular matrix." "The stroma is mainly composed of large, multinucleated cells." "The stroma contains densely packed cells with distinct cytoplasmic borders." "The stroma is composed of cells with indistinct cytoplasmic borders, suggesting a proliferative state." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/36.jpg" -"37" "What does the larger arrow in the image likely indicate?" "Necrotic tissue areas" "An area of vascular hyperplasia" "Clusters of lymphocytes" "Metastatic cancer cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/37.jpg" -"38" "What staining characteristic of the basement membranes is observed in this image?" "Silver stain black/brown staining" "Periodic acid-Schiff (PAS) magenta/purple staining" "Masson's trichrome blue/green staining" "Hematoxylin and Eosin (H&E) blue/purple staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/38.jpg" -"39" "Based on the morphology seen in the image, how would you describe the architecture of the hypercellular glomerulus?" "Lobular" "Collapsed" "Sclerotic" "Diffuse" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/39.jpg" -"40" "Considering the organization of the cells in this tissue sample, what can be inferred about the overall structure?" "The cells are arranged in tight clusters similar to glandular epithelium" "The cells display a palisading pattern common in neuropathological conditions" "The cells show a high degree of uniformity and regular arrangement typical of healthy tissue" "There is a disordered arrangement with a lack of regularity suggesting a pathological or reactive process" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/40.jpg" -"41" "What is the orientation of the nuclei in the columnar epithelial cells?" "Centrally located nuclei" "Apically located nuclei" "Basally located nuclei" "Randomly distributed nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/41.jpg" -"42" "The rounded, empty spaces in the central region of the image are likely to be:" "Lipid vacuoles within the cells" "Cytoplasmic inclusions within neoplastic cells" "Viable cells undergoing mitosis" "Artifacts from tissue processing" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/42.jpg" -"43" "Analyzing the inset with higher magnification, what can be identified within the indicated cell?" "Large vesicles representing lysosomal structures" "Formation of merozoites within a Type II meront" "Lipid droplets approximately 3 to 4 micrometers in diameter" "Apoptotic bodies due to programmed cell death" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/43.jpg" -"44" "What feature is indicative of the Mott cells present in the lamina propria?" "Cells with extensive cytoplasmic vacuolization" "Cells with small, dark-staining nuclei" "Cells with high nuclear to cytoplasmic ratio" "Cells with large pale cytoplasm and eccentrically placed nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/44.jpg" -"45" "Considering the epithelial integrity, what can be deduced about the epithelial surface?" "There is complete loss of epithelium over the entire sample" "The epithelium is entirely intact without any disruption" "There is focal disruption of the surface epithelium" "The epithelium displays high-grade dysplasia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/45.jpg" -"46" "What feature is distinguished by the presence of elongated, spindle-shaped nuclei as indicated by white arrows in this histological image?" "Glandular epithelium" "Adipose tissue" "Smooth muscle cells" "Connective tissue stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/46.jpg" -"47" "The Hematoxylin and Eosin (H&E) staining in this image shows the stroma colored in what hue, suggesting a richness in connective tissue fibers?" "Blue to green" "Red to yellow" "Pink to purple" "Black to brown" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/47.jpg" -"48" "What is the predominant staining pattern observed in the neoplastic cells’ cytoplasm within this image?" "Homogenous light pink staining" "Dark blue with speckled areas" "Strong brown staining" "Multinucleated giant cells with peripheral staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/48.jpg" -"49" "What characteristic appearance is given by some of the neoplastic cells due to their nuclear placement?" "A spindle cell appearance" "A plasmacytoid appearance" "An epithelioid appearance" "A signet-ring cell appearance" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/49.jpg" -"50" "What do the variations in size and shape of the nuclei of the tubular epithelial cells suggest?" "Advanced renal cell carcinoma" "A high level of cellular anaplasia" "A normal level of cellular polarity and differentiation" "Presence of significant necrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/50.jpg" -"51" "Based on the presence of striated patterns, which type of muscle tissue is depicted in this microscopic view?" "Smooth muscle" "Skeletal muscle" "No muscle tissue present" "Cardiac muscle" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/51.jpg" -"52" "Identify the areas in the tissue that are indicative of glycogen deposition based on the staining pattern." "Areas represented by an open arrowhead with more intense staining" "Areas of lighter staining close to the sarcolemma and in association with the intercalated discs" "Areas of darker staining close to the intercalated discs" "Areas immediately surrounding the centrally located nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/52.jpg" -"53" "Based on the immunocytochemical staining pattern observed in the image, what is the most likely identity of the positively stained cells?" "Hepatocytes" "Lymphocytes" "Mesothelial cells" "Neurons" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/53.jpg" -"54" "Based on the histopathological features, what is the most likely pattern of growth observed in this ovarian tumor?" "A cystic growth pattern with fluid-filled spaces" "A papillary growth pattern with finger-like projections" "A diffuse infiltrative growth pattern with individual cells spread throughout the stroma" "A neoplastic solid growth pattern with dense cell clusters" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/54.jpg" -"55" "The inset image depicts nuclear staining indicative of which marker's expression in the tumor cells?" "Estrogen receptor (ER)" "Progesterone receptor (PR)" "Cytokeratin (CK)" "Thyroid transcription factor-1 (TTF-1)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/55.jpg" -"56" "Based on the cellular morphology, what cellular elements are most prevalent in the background of this image?" "Lymphocytes" "Polymorphonuclear leukocytes" "Monocytes" "Eosinophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/56.jpg" -"57" "Considering the architecture of the cells and their arrangements, which statement is accurate regarding the organization of the tissue?" "The cells are arranged in a uniform, glandular pattern" "The tissue displays a lack of normal tissue architecture" "The tissue consists of well-organized squamous epithelium" "The cells form organized and differentiated tissue structures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/57.jpg" -"58" "When assessing the condition of the capillary walls in the glomerulus in the image, what can be inferred?" "There is a dramatic increase in capillary wall porosity and fragmentation" "There is a thickening of the capillary walls due to mesangial expansion" "Capillary walls exhibit significant aneurysmal dilation" "The capillary walls are thin and delicate without noticeable alterations" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/58.jpg" -"59" "Based on the immunohistochemical staining observed, what is the predominant cellular antigen expression pattern?" "No staining" "Membranous staining" "Cytoplasmic staining" "Nuclear staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/59.jpg" -"60" "When assessing the overall cellular morphology, what characteristic is primarily exhibited by the cells?" "Round to ovoid with distinct cell boundaries" "Multinucleated giant cells" "Spindle-shaped morphology" "Pleomorphic with high mitotic rate" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/60.jpg" -"61" "What does the appearance of the cell nuclei stained in this cytological preparation suggest about the staining method used?" "Periodic acid-Schiff (PAS) stain" "Diff-Quik stain" "Giemsa stain" "Hematoxylin and Eosin (H&E) stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/61.jpg" -"62" "Considering the cell morphology and staining characteristics visible in the image, which cell population exhibits the greatest variation in size?" "The cells comprising the background material." "The smaller cells with high nucleus-to-cytoplasm ratio." "All cell populations show similar variation in size." "The large polygonal cells with abundant granular cytoplasm." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/62.jpg" -"63" "What morphological feature of the nuclei could be an indication of cellular activity level in the large polygonal cells stained with May-Grunwald Giemsa?" "The faint staining intensity of the nuclei." "The size of the nucleoli relative to the nuclei." "The centralized location of the nucleoli within the nuclei." "The irregular shape of the nuclei." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/63.jpg" -"64" "What histological feature of the tissue suggests a possible reaction to chronic inflammation?" "Presence of neutrophils" "Presence of epithelioid cells" "Presence of multinucleated giant cells" "Presence of lymphocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/64.jpg" -"65" "Based on staining intensity, how would you classify the cells marked with stars in this renal tissue section?" "Cells with high metabolic activity" "Cells with low expression of caspase-3" "Cells undergoing mitosis" "Cells with high expression of caspase-3" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/65.jpg" -"66" "Which description best fits the renal tubules marked with 'P' in this micrograph?" "Tubules with cells exhibiting high expression of caspase-3" "Tubules with significant cellular debris in the lumen" "Tubules containing cells that are likely necrotic" "Tubules showing signs of exceptional regeneration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/66.jpg" -"67" "What is the morphological characteristic of the cell indicated by the arrow?" "Small cell with high nucleus-to-cytoplasm ratio" "Large cell with a hypersegmented nucleus" "Cell with relatively abundant cytoplasm and blue granules" "Cell with multiple small vacuoles within the cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/67.jpg" -"68" "What is the predominant morphological feature of the squamous cells in this tissue section?" "Uniform nuclei and consistent cell size" "Hyperchromatic nuclei with increased nuclear-to-cytoplasmic ratios" "Cells are well-differentiated with distinct keratinization" "Small, round blue cells with scant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/68.jpg" -"69" "Which statement best describes the stromal characteristics of this tissue section?" "Contains a mixed inflammatory cell infiltrate, disrupting the normal tissue architecture" "Contains a mixed inflammatory cell infiltrate without significant disruption of the tissue architecture" "Composed of densely packed collagen fibers with low cellularity" "Predominantly acellular with areas of necrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/69.jpg" -"70" "In the given histological image, what cellular morphology is mainly exhibited by the epithelium on the right side?" "Flat, sheet-like cells with a relatively uniform appearance and central nuclei" "Round cells with peripherally located nuclei and clear cytoplasm" "Irregularly shaped cells with scattered hyperchromatic nuclei" "Tall, columnar cells with basally located nuclei and mucous secretion" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/70.jpg" -"71" "The arrangement of the cells in the image is indicative of which of the following?" "Normal tissue differentiation" "Neoplastic cellular changes" "Recovery from tissue injury with fibroblasts" "Inflammation with neutrophil infiltration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/71.jpg" -"72" "What type of inflammatory cells predominate in the interstitium of this kidney tissue section?" "Lymphocytes" "Macrophages" "Neutrophils" "Plasma cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/72.jpg" -"73" "What is the predominant cell shape observed in the epithelial layer of the tissue?" "Cuboidal" "Squamous" "Columnar" "Transitional" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/73.jpg" -"74" "What type of connective tissue is predominantly visible on the left side of this microscopic image?" "Dense regular connective tissue" "Elastic connective tissue" "Reticular connective tissue" "Dense irregular connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/74.jpg" -"75" "Which feature in the microscopic image can be used to identify adipose tissue?" "Spindle-shaped cells with elongated nuclei and abundant cytoplasm" "Large, vacuolated cells with centralized spherical nuclei" "Cells with peripheral, flattened nuclei and a small amount of cytoplasm" "Compact cell arrangement with scant intercellular space" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/75.jpg" -"76" "How does the cytoplasm of the cells present in the image appear?" "Eosinophilic and granular" "Clear and vacuolated" "Abundant and basophilic" "Sparse and homogeneous" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/76.jpg" -"77" "What can be deduced about the surrounding tubular structures in this pathological image?" "Tubular microcysts are present, indicating advanced polycystic kidney disease" "The tubules appear relatively preserved without significant pathology" "The tubules show evidence of acute tubular necrosis" "There is extensive tubular atrophy and interstitial fibrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/77.jpg" -"78" "What does the pink-stained material in the glomerulus likely represent?" "Red blood cell casts" "Sclerosis and hyalinosis" "Active glomerular inflammation" "Normal capillary loops" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/78.jpg" -"79" "What does the cellular organization in the image suggest?" "Organized into structures that suggest papillary formations" "Well-differentiated cells with regular architecture" "Anaplastic cells with no discernible patterns" "Uniform, non-neoplastic tissue organization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/79.jpg" -"80" "What feature does the long arrow at the top of the image primarily indicate?" "Multiple layers of squamous epithelial cells" "Uniform eosinophilic matrix with embedded chondrocytes" "Areas of high cellularity with pleomorphic nuclei" "Fibrous connective tissue with abundant collagen fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/80.jpg" -"81" "Identify the characteristics of the region where the short arrow is pointing at the bottom of the image." "Disarrayed stroma with scattered neoplastic cells" "Hyperchromatic nuclei in a crowded glandular arrangement" "Viscous mucous production typical of mucinous adenocarcinoma" "Dense, eosinophilic matrix with spaces indicative of marrow elements" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/81.jpg" -"82" "Based on the immunohistochemical stain of section A, which marker is most likely targeted given the pattern and color of staining?" "Estrogen Receptor" "S100 protein" "Synaptophysin" "CD34" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/82.jpg" -"83" "In section B, what does the observable cellular morphology suggest about the nature of the cells?" "Neuroendocrine tumor" "Benign fibroblastic proliferation" "Acute inflammatory infiltrate" "Normal colonic epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/83.jpg" -"84" "What histological feature is absent in the cells within this image that can help differentiate them from another cell type?" "Condensed chromatin" "Cytoplasmic granules" "Presence of nucleoli within the nuclei" "Multi-nucleation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/84.jpg" -"85" "Considering the tissue organization observed, which of the following best describes the distribution and structural arrangement seen in the image?" "Palisading arrangement of nuclei" "High cell density with minimal intervening stroma" "Glandular structures with polarized epithelial cells" "Rosette formation around a central lumen" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/85.jpg" -"86" "What type of nuclear change can be predominantly seen in the keratinocytes from the tissue section?" "Ballooned nuclei with ground-glass appearance" "Hyperchromatic nuclei" "Cleaved nuclei" "Vesicular nuclei with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/86.jpg" -"87" "What can be deduced about the cellularity of the lamina propria based on the microscopic examination of the tissue?" "Presence of granulomatous inflammation" "Dense concentration of neutrophils" "Dense concentration of lymphocytes" "Decreased cellularity with few inflammatory cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/87.jpg" -"88" "Considering the cellular arrangement in the connective tissue as seen in the image, which pattern of inflammatory cell distribution is identified?" "Granulomatous arrangement with centralized histiocytes" "Aggregation of eosinophils around blood vessels" "Scattered and diffuse lymphocytes throughout the connective tissue" "Band-like pattern of lymphocytic infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/88.jpg" -"89" "Based on the cellular morphology observed in the image, which type of cell is predominantly infiltrating the fibrotic stroma?" "Eosinophils" "Neutrophils" "Plasma cells" "Macrophages" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/89.jpg" -"90" "In the image, what is the pinkish extracellular material indicative of?" "Fatty tissue" "Fibrotic tissue" "Granulation tissue" "Neural tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/90.jpg" -"91" "What is the predominant shape of the cells observed in this tissue section?" "Polyhedral" "Cuboidal" "Spindle-shaped" "Spherical" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/91.jpg" -"92" "What red blood cell shape abnormality is apparent in this microscopic image?" "Schistocytosis" "Ovalocytosis" "Poikilocytosis" "Spherocytosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/92.jpg" -"93" "Based on the appearance of the nuclei in the leukocytes within this image, what abnormality can be inferred?" "Mononuclear" "Hyposegmentation" "Hypersegmentation" "Pelger-Huet anomaly" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/93.jpg" -"94" "Based on the size and cytoplasmic characteristics of cells in the image, what cellular morphology can be inferred?" "The cells are small with scant cytoplasm." "The cells are uniformly small with a high nuclear-to-cytoplasmic ratio." "The cells are mostly large with ample cytoplasm." "The cell size and amount of cytoplasm are too variable for any conclusive morphology." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/94.jpg" -"95" "What can be inferred about the nuclei of the cells observed in this image?" "The nuclei exhibit a fine and evenly dispersed chromatin pattern" "The nuclei appear uniform in shape and size" "The nuclei are hyperchromatic with irregular shapes" "The nuclei show a decreased nuclear-to-cytoplasmic ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/95.jpg" -"96" "Based on the staining characteristics, how would you describe the cytoplasm of the cells in the image?" "The cytoplasmic staining is eosinophilic" "The cytoplasmic staining shows glycogen deposits" "The cytoplasmic staining is basophilic" "The cytoplasmic staining is predominantly clear" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/96.jpg" -"97" "What is not evident in the field of view regarding the cellular arrangement?" "Cohesive nature of the cellular cluster" "Presence of isolated cells and cellular debris" "Formation of papillary structures" "Cytolysis of individual cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/97.jpg" -"98" "What morphological change can be observed in the glomerulus indicated by the thin arrow?" "Thickening of the glomerular basement membrane" "Effacement of podocyte foot processes" "Segmental areas of increased matrix and obliteration of capillary lumens" "Proliferation of mesangial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/98.jpg" -"99" "In the area of the tubular structure indicated by the thick arrow, what is the characteristic feature of the nuclei?" "Multinucleation" "Hyperchromasia" "Binucleation" "Disproportionately large size compared to the cell" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/99.jpg" -"100" "What cellular phenomenon is notably marked by the orange arrow in this microscopic image?" "Apoptosis" "Emperipolesis" "Phagocytosis" "Karyorrhexis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/100.jpg" -"101" "Based on the number of cells and density of the cell nuclei, what is the predominant cell type in the background of this image?" "Epithelial cells" "Fibroblasts" "Endothelial cells" "Lymphocytes and plasma cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/101.jpg" -"102" "Based on the pattern of cell arrangement in the image provided, which of the following terms best describes the organization of the neoplastic cells?" "Nested pattern" "Dispersed pattern" "Rosette pattern" "Palisading pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/102.jpg" -"103" "Regarding the nuclear features of the cells observed in the image, what observation can be made?" "Hyperchromatic nuclei" "Multinucleated cells" "Anisokaryosis" "Uniform round nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/103.jpg" -"104" "What is the most prominent feature of the cells marked by red arrows?" "Abundant granular cytoplasm" "Presence of multiple nuclei" "Irregular or lobulated nuclear contours" "Large, distinct vacuoles within the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/104.jpg" -"105" "Considering the appearance of the nuclei, what can be inferred about the maturation stage of the myeloid cells marked with red arrows?" "Late-stage maturation nearing the end of the cell's lifespan" "Early-stage maturation with loose chromatin" "Unable to determine maturation stage from this image" "Intermediate-stage maturation with a dense, darkly staining nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/105.jpg" -"106" "What does the pink-stained area surrounding the cells suggest about the composed tissue, according to the image analysis?" "Evidence of significant fibrosis" "Staining of red blood cells" "Indication of axonal and dendritic processes with glial support" "Presence of high fat content" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/106.jpg" -"107" "What is the predominant morphological feature of the nuclei observed in the cell clusters?" "Monomorphic appearance" "Multinucleation" "Pleomorphism" "Uniform size and shape" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/107.jpg" -"108" "What does the histological feature of the stroma indicate about the extracellular matrix?" "Dense fibrous extracellular matrix" "Scant extracellular matrix" "Hyalinized extracellular matrix" "Hyperplastic extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/108.jpg" -"109" "What histological feature is notably absent from the chorionic villi observed in this image?" "Evidence of acute inflammation" "Presence of fibroblast proliferation" "Abnormal trophoblastic infiltration" "Signs of villous necrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/109.jpg" -"110" "Based on the microscopic image of the tissue presented, which of the following best describes the cyst's content?" "Predominantly lymphocytes" "Eosinophilic homogenous material" "Abundant red blood cells" "Numerous tightly packed granular elements" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/110.jpg" -"111" "What characteristic of the spindle-shaped cells in the submucosa suggests that they are fibroblasts?" "Their location within the submucosal layer" "Their basophilic (dark purple/blue) staining nuclei" "Their hollow, tube-like spaces" "Their scattered appearance among the extracellular matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/111.jpg" -"112" "What type of cell does the green arrow point to in the image?" "Histiocytes" "Fibroblasts" "Squamous epithelial cells" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/112.jpg" -"113" "By examining the background infiltrate of cells, what can be inferred about the type of inflammatory response occurring?" "Acute neutrophilic inflammation" "Eosinophilic inflammation" "Lymphocytic infiltration" "Chronic granulomatous inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/113.jpg" -"114" "Based on the cellular organization of the epithelium in the image, which description best characterizes the observed morphology?" "There is evidence of well-organized epithelial layering with regular intercellular connections" "The cellular arrangement appears disorganized with nuclei at various heights" "The cells demonstrate a uniform, honeycomb-like hexagonal appearance" "The nuclei are located at a single uniform level within each cell" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/114.jpg" -"115" "What might the varying density of the stromal components in the image indicate?" "Consistent fibrosis indicating a benign process" "Presence of inflammatory cells within the reactive stroma" "Uniform stress distribution throughout the stroma" "Reactive changes often present in the context of neoplastic growth" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/115.jpg" -"116" "What is the predominant staining pattern seen in the endothelial cells lining the tubular structures?" "Punctate dark staining concentrated at the periphery of the structures" "Uniformly light staining throughout the structures" "Brown staining following the tubular contours" "Homogeneous dark staining filling the entire luminal space" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/116.jpg" -"117" "In the epidermis shown, which layer is characterized by a high density of condensed nuclei and an abundance of eosinophilic cytoplasm?" "Dyskeratotic cells" "Stratum spinosum" "Stratum corneum" "Stratum granulosum" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/117.jpg" -"118" "How would you describe the appearance and likely identity of the smaller, darker-stained cells within the connective tissue stroma?" "Erythrocytes with biconcave shape" "Lymphocytes with condensed chromatin" "Fibroblasts with spindle-shaped nuclei" "Neutrophils with multi-lobed nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/118.jpg" -"119" "Based on the appearance of the hepatocytes in this liver tissue section, what is the most likely change observed?" "Ballooning degeneration" "Mallory bodies" "Vacuolation" "Ground-glass appearance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/119.jpg" -"120" "What observation can be made about the sinusoidal spaces in this liver tissue section?" "The sinusoidal spaces appear dilated and engorged" "The sinusoidal spaces appear patent without significant changes" "The sinusoidal spaces are obliterated by the infiltration of inflammatory cells" "The sinusoidal spaces appear compressed by surrounding fibrotic tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/120.jpg" -"121" "In the provided microscopic image of the tissue section, what do the elongated, pink-stained structures primarily represent?" "Collagen fibers" "Purkinje fibers" "Adipose tissue infiltrates" "Myocardial tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/121.jpg" -"122" "What can be inferred about the cellularity of the marrow from this image?" "Normal cellularity" "Hypercellular marrow" "Acellular marrow" "Myelofibrosis with collagen deposition" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/122.jpg" -"123" "Which of the following features best describes the morphology of the cells lining the vascular channels?" "Cuboidal morphology with central round nuclei" "Small, round cells with peripherally located nuclei" "Spindle-shaped with elongated dark-staining nuclei" "Large, polygonal cells with prominent nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/123.jpg" -"124" "How would you describe the typical morphology of the cells in this tissue section?" "Columnar with eosinophilic cytoplasm" "Cuboidal with prominent nucleoli" "Round with distinct cell boundaries" "Spindle-shaped with elongated and tapered ends" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/124.jpg" -"125" "What cellular characteristic predominantly signifies the main cellular population in this liver tissue section?" "Prominent central nuclei with abundant cytoplasm" "Hyperchromatic and pleomorphic nuclei" "Abundance of binucleated cells" "Cells with a high nuclear-to-cytoplasmic ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/125.jpg" -"126" "Based on the cytoplasmic characteristics observed in the micrograph, what type of cells can be identified apart from the hepatocytes?" "Cells with densely eosinophilic cytoplasm and multiple nuclei" "Cells with foamy cytoplasm without visible nuclei" "Cells with clear cytoplasm and peripheral nuclei" "Cells with foamy cytoplasm containing dark-staining particles" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/126.jpg" -"127" "Based on the in situ hybridization staining pattern observed, what is the most likely interpretation of the cellular distribution of the target nucleic acid sequences on the right section of the image?" "The target sequences are equally distributed between the nucleus and the cytoplasm." "There is no presence of the target sequences in the cells." "The target sequences are present predominantly in the cytoplasm." "The target sequences are present predominantly in the nucleus." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/127.jpg" -"128" "What feature, in terms of staining, differentiates the two sections of the tissue sample displayed in the image?" "The left section demonstrates a homogeneous light staining in the cytoplasm." "The right section shows a lack of any staining." "The left section shows a lack of staining in both the nucleus and the cytoplasm." "The right section exhibits a homogeneous staining of the nucleus and cytoplasm." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/128.jpg" -"129" "What can be inferred about the tissue architecture from the image?" "The tissue is composed of dense sheets of cells with scant visible stroma in between." "The tissue displays separated clusters of cells without visible stromal tissue." "The tissue comprises loosely arranged cells with significant stromal content." "The tissue consists of dense sheets of cells with an abundance of stroma." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/129.jpg" -"130" "What staining technique is indicated by the distinct purple and pink hues of the cells in this microscopic image?" "May-Grünwald-Giemsa (MGG) staining" "Wright's staining" "Hematoxylin and Eosin (H&E) staining" "Acid-fast bacilli (AFB) staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/130.jpg" -"131" "How would you describe the arrangement of the nuclear shapes of the cells dispersed among the fibers?" "Predominantly oval and elongated" "Uniformly small and hyperchromatic" "Diverse with multi-lobed forms" "Predominantly circular and compact" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/131.jpg" -"132" "Considering the overall architecture of the tissue, which statement is true?" "There is a lack of normal brain tissue organization" "The fibers are thin and loosely dispersed" "There is a clear distinction between gray and white matter" "The cellularity is uniformly low across the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/132.jpg" -"133" "What is the arrangement of the cells in this tissue sample?" "Arranged in glandular configurations" "Disorganized with no specific pattern" "Organized in solid nests" "Scattered individually with no cohesion" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/133.jpg" -"134" "In the provided image, which type of inflammatory cells predominate in the area adjacent to the necrotic muscle fibers?" "Basophils" "Eosinophils" "Lymphocytes" "Neutrophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/134.jpg" -"135" "Based on the characteristics of the nuclei, what type of cells predominates in this tissue sample?" "Cells with hypersegmented nuclei" "Cells with bi-lobed nuclei" "Cells with monolobed nuclei" "Cells with multinucleated giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/135.jpg" -"136" "What does the arrangement of the extracellular matrix suggest about the type of tissue captured in this image?" "Dense connective tissue with closely packed collagen fibers" "Hyaline cartilage with glassy extracellular matrix" "Bone tissue with calcified extracellular matrix" "Subcutaneous connective tissue with loose, fibrous structure" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/136.jpg" -"137" "What does the cell architecture in the image suggest about the neoplasm's differentiation status?" "The structured arrangement indicates a well-differentiated neoplasm" "The disorganized growth pattern suggests an undifferentiated neoplasm" "The lack of distinct cell population implies a poorly differentiated neoplasm" "The presence of homogenous cell types suggests a moderately differentiated neoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/137.jpg" -"138" "What is the predominant pattern of the cells identified in this microscopic image?" "Round cells forming rosette-like structures" "Spindle-shaped in a disorganized arrangement" "Lymphoid with scattered distribution" "Epithelioid with cohesive clusters" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/138.jpg" -"139" "What is the implication of the presence of smaller cells with high nuclear-to-cytoplasmic ratios adjacent to the large macrophages?" "Immune response" "Tissue regeneration" "Acute inflammatory response" "Cellular dysplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/139.jpg" -"140" "What cellular morphology is demonstrated in Panel A?" "Lymphoid follicles with germinal centers" "Disorganized neoplastic cells" "Columnar epithelial cells with apical orientation" "Uniform spindle-shaped cells characteristic of smooth muscle" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/140.jpg" -"141" "What does the histological pattern seen in Panel B suggest about the protein expression?" "Diffuse cytoplasmic expression" "Heterogeneous expression within the tissue section" "Restricted expression to the extracellular matrix" "Localized expression in cell membranes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/141.jpg" -"142" "What feature is indicated by the arrows within the epithelial layer?" "Squamous epithelial cells" "Neutrophils" "Eosinophils" "Basal cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/142.jpg" -"143" "Based on the histological features, what is indicated by the black asterisk?" "Vascular structure" "Glandular tissue" "Dense fibrosis" "Muscularis propria" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/143.jpg" -"144" "Based on the histological features observed, what does the circular structure in the tissue likely represent?" "An adipose cell" "A cross-section of a blood vessel" "A nerve bundle" "A psammoma body" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/144.jpg" -"145" "What does the pink to purple coloration primarily indicate in this haematoxylin and eosin-stained histological section?" "Areas of necrosis" "Nuclear material" "Collagen fibers" "Cytoplasm and extracellular matrix" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/145.jpg" -"146" "Based on the histological features observed, what cellular morphology is most prevalent in this section?" "Cells with high nuclear-to-cytoplasmic ratio, having hyperchromatic nuclei" "Cells with abundant cytoplasm and centrally located nuclei" "Adipocytes with large lipid vacuoles and compressed nuclei" "Cells with eccentrically placed nuclei and perinuclear halo" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/146.jpg" -"147" "What characteristic feature of the epidermis can be seen in this image?" "Thin and elongated rete ridges" "Hyperkeratosis" "Parakeratosis" "Acantholysis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/147.jpg" -"148" "Based on the band-like accumulation of inflammatory cells, what is the probable pattern of inflammation observed in this image?" "Granulomatous inflammation" "Psoriasiform hyperplasia" "Lichenoid infiltrate" "Spongiosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/148.jpg" -"149" "Based on the cytoplasmic staining observed in the main area of the image, what protein is most likely highlighted in the myoepithelial cells?" "Desmin" "Vimentin" "Smooth muscle actin" "Cytokeratin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/149.jpg" -"150" "In the inset of the image, what does the nuclear staining suggest about the cell type?" "Epithelial cells" "Fibroblasts" "Adipocytes" "Myoepithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/150.jpg" -"151" "How would you characterize the distribution and amount of stromal tissue visible in this microscopic image?" "Moderate stromal tissue with evidence of reactive changes" "Scant stromal tissue distributed sporadically between cells" "Stromal tissue exhibiting hyalinization or sclerosis" "Abundant stromal tissue separating well-differentiated cell clusters" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/151.jpg" -"152" "When examining the granular layer (stratum granulosum) of the epidermis in this image, which observation is most accurate?" "The layer appears less pronounced than usual" "The layer is thick and prominent" "The layer is multilayered with prominent keratohyalin granules" "The layer contains darkly staining granules" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/152.jpg" -"153" "Based on the HE staining, what type of inflammatory cells predominate in the areas of cell accumulation?" "Eosinophils" "Macrophages" "Neutrophils" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/153.jpg" -"154" "What is the hallmark feature observed in the muscle fibers that indicates degeneration?" "Multinucleated giant cells" "Loss of cross striations" "Perifascicular atrophy" "Central nucleation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/154.jpg" -"155" "What is the predominant cytoplasmic staining characteristic in the observed cells?" "Amphiphilic" "Eosinophilic" "Neutrophilic" "Basophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/155.jpg" -"156" "Based on the glomerulus indicated by the left orange arrow, which of the following best describes its morphology?" "Enlarged glomerulus with proliferative changes" "Hypercellular glomerulus with crescent formation" "Shrunken glomerulus with collapsed capillary loops" "Normal glomerular size with open capillary loops" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/156.jpg" -"157" "Considering the renal tubule adjacent to the right orange arrow, how would you characterize it?" "Tubule with normal luminal diameter" "Tubule showing evidence of dilation" "Atrophic tubule with thickened basement membrane" "Tubule with significant cellular atypia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/157.jpg" -"158" "In terms of pathology, what is the most likely finding that can be observed in the space surrounding the tubules and glomeruli?" "Marked lymphocytic infiltration" "No obvious increase in cellularity" "Extensive necrosis of interstitial tissue" "Significant interstitial fibrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/158.jpg" -"159" "What cellular feature is indicated by the arrows in this histological section of liver tissue?" "Kupffer cell hyperplasia" "Interface hepatitis" "Hepatocyte ballooning" "Hepatic steatosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/159.jpg" -"160" "In the main image, what cellular feature is highlighted by the arrows?" "Spindle-shaped nuclei with multiple nucleoli" "Multiple prominent nucleoli within the nucleus" "Large, clear vacuoles within the cytoplasm" "Dense lipofuscin granules within the cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/160.jpg" -"161" "What is the main characteristic observed in the granules of the inset image?" "The granules are large and densely accumulated" "The granules are small and lightly stained" "The granules are small and densely stained" "The granules are large and sparsely distributed" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/161.jpg" -"162" "Observing the nuclei of the cells in the image, what could be inferred about the mitotic activity?" "Several mitotic figures indicating a high mitotic rate" "Few scattered mitotic figures consistent with a low mitotic rate" "Normal mitotic figures typically seen in benign lesions" "Absence of mitotic figures suggesting quiescent cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/162.jpg" -"163" "Considering the stromal component of the tissue, what is predominantly observed in this microscopic image?" "Homogeneous acellular material surrounding the tumor clusters" "Ample myxoid matrix intermixed with the cell clusters" "Dense collagen bundles forming a rigid, fibrous stroma" "Abundant adipose tissue displacing the cell nests" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/163.jpg" -"164" "Based on the cellular morphology, which feature is NOT evident in the glandular epithelium?" "Significant nuclear pleomorphism" "Hyperchromatic nuclei" "Presence of columnar epithelial cells" "Increased mitotic activity" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/164.jpg" -"165" "What can be deduced about the gland-to-stroma ratio in this tissue sample?" "Equal balance of glands and stroma" "Slightly increased gland-to-stroma ratio" "A markedly increased gland-to-stroma ratio" "Reduced number of glands compared to stroma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/165.jpg" -"166" "What is the nuclear-to-cytoplasmic ratio observed in the cells within this image?" "Low nuclear-to-cytoplasmic ratio" "Indeterminable nuclear-to-cytoplasmic ratio" "High nuclear-to-cytoplasmic ratio" "Moderate nuclear-to-cytoplasmic ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/166.jpg" -"167" "How would you describe the appearance of the nuclei within the cell clusters in this microscopic image?" "Pleomorphic nuclei with varying sizes and shapes" "Nuclei with significant clearings and prominent nucleoli" "Pyknotic nuclei with condensed chromatin" "Hyperchromatic nuclei with a consistent shape" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/167.jpg" -"168" "Based on the membrane localization of the brown staining, which cell adhesion molecule is likely being expressed in the highlighted areas of the tissue?" "E-cadherin" "Vimentin" "Cytokeratin" "N-cadherin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/168.jpg" -"169" "Based on the staining patterns observed, what type of staining technique is likely used in this image?" "Gram staining" "Immunocytochemical staining" "Hematoxylin and eosin (H&E) staining" "Periodic acid–Schiff (PAS) staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/169.jpg" -"170" "Which protein's expression pattern is likely indicated by the brown chromogen staining observed in the image?" "Keratin" "Actin" "Paxillin" "Hemoglobin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/170.jpg" -"171" "Evaluating the morphological characteristics of the nuclei within the spindle-shaped cells, which finding is consistent with the image?" "Small, uniform nuclei with dense chromatin" "Large, hyperchromatic nuclei with irregular contours" "Multinucleated giant cells" "Nuclei showing prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/171.jpg" -"172" "How does the tissue architecture surrounding the hair follicle appear?" "Fibrotic with excessive collagen deposition" "Neoplastic expansion with irregular bordering" "Normal with well-preserved structure" "Disrupted with dense inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/172.jpg" -"173" "What is the nature of the cells making up the crescentic structures in the glomeruli?" "Cells with lipid accumulation" "Neoplastic cells with atypical nuclei" "Heterogeneous population of cells with varied staining" "Uniform cells with a homogeneous appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/173.jpg" -"174" "Considering the tissue architecture presented in this image, how would you classify the level of organization?" "Moderately organized with some discernible structures" "Slightly disorganized but with recognizable tissue patterns" "Highly organized with clear glandular structures" "Disorganized with no resemblance to normal tissue architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/174.jpg" -"175" "What can be inferred about the cytoplasmic features of the cells from this microscopic image?" "Granular eosinophilic cytoplasm" "Scant, amphophilic cytoplasm" "Scant, acidophilic cytoplasm with a pinkish hue" "Abundant basophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/175.jpg" -"176" "Based on the architectural features observed in the image, what is the most likely anatomical location of this tissue?" "Gastric antrum" "Esophageal epithelium" "Jejunal mucosa" "Colonic mucosa" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/176.jpg" -"177" "Based on the cellular morphology observed in the image, what is the predominant nuclear characteristic of the atypical epithelioid cells?" "Regular nuclear contours" "Uniform nuclear size and shape" "Occasional irregularities of the nuclear borders" "Homogenous chromatin distribution" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/177.jpg" -"178" "Considering the hematoxylin and eosin (H&E) staining and the cellular arrangement, what feature best describes the clustering of epithelioid cells?" "Clusters with smooth contouring suggesting organization" "Large, dense clusters with necrosis" "Clusters with irregular contouring and extensive cell overlapping" "No significant clustering, predominantly isolated cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/178.jpg" -"179" "What feature is indicated by the arrows in the gland-like structures?" "Acute inflammation" "Normal cell differentiation" "Atrophy" "High-grade dysplasia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/179.jpg" -"180" "Based on what is visible in image section 'C', what is the primary histological characteristic of the visible dermal component?" "Predominance of eosinophilic fibrous tissue" "Extensive vascularization" "Abundance of elastin fibers" "Heavy inflammatory cell infiltrate" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/180.jpg" -"181" "Based on the microscopic features observed in the image, which type of staining appears to have been used to highlight the collagen and fibrous tissue?" "Hematoxylin and eosin stain" "Periodic acid-Schiff stain" "Van Gieson stain" "Masson's trichrome stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/181.jpg" -"182" "What pathology is indicated by the thickened or collapsed capillary loops within several glomeruli observed in the image?" "Membranous nephropathy" "Amyloidosis" "Acute tubular necrosis" "Glomerular sclerosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/182.jpg" -"183" "What cytopathic feature is characteristic of the large cells evident in the image?" "Squamous epithelial cells" "Signet ring cells" "Multi-nucleated giant cells" "Reed-Sternberg cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/183.jpg" -"184" "Which histological feature seen in the image suggests an underlying reactive or inflammatory process?" "The presence of neutrophils" "An abundance of eosinophils" "A mixture of small mononuclear cells" "A predominance of small lymphocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/184.jpg" -"185" "What can be inferred about the differentiation of squamous epithelial cells from the observed tissue sample?" "Surface cells are heavily keratinized with clear nuclei" "Cells show uniform cytoplasmic eosinophilia throughout all layers" "Cells near the surface retain their nuclei instead of losing them" "Cells exhibit normal stratification and surface cells are anucleated" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/185.jpg" -"186" "Considering the morphological features and density of the cells present in the image, what tissue characteristic does this most likely represent?" "Loose connective tissue" "Adipose tissue" "Highly cellular neoplasm" "Hyaline cartilage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/186.jpg" -"187" "Based on the tissue morphology, what type of epithelium lines the topmost layer of this tissue section?" "Transitional epithelium" "Squamous epithelium" "Columnar epithelium" "Cuboidal epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/187.jpg" -"188" "Which layer in the cerebellar tissue shows the highest expression of mGluR1 protein as indicated by the density of brown staining?" "Granule cell layer" "White matter" "Molecular layer" "Purkinje cell layer" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/188.jpg" -"189" "Based on the absence of brown staining, which cerebellar structure appears to show a lack of expression for the mGluR1 protein?" "Dendritic trees of Purkinje cells" "Granule cell layer" "Cell bodies of Purkinje cells" "White matter" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/189.jpg" -"190" "What structures can be identified at the top area of the image?" "Solid epithelial nests" "Blood vessels or ducts lined by epithelial-like cells" "Foci of calcification" "Necrotizing granulomas" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/190.jpg" -"191" "The eosinophilic (pink-staining) structure within the wall of one of the dilated spaces suggests what type of pathological process?" "An acute inflammatory response" "A neoplastic growth" "A chronic infection or insult" "A recent hemorrhagic event" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/191.jpg" -"192" "What is the staining characteristic that is predominantly observed in the cytoplasm of the cells?" "Giemsa stain affinity demonstrating deep purple cytoplasmatic features" "Periodic Acid-Schiff (PAS) positivity showing magenta granules" "Hematoxylin-only staining resulting in exclusively blue cytoplasm" "Eosin-only staining leading to a brightly pink cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/192.jpg" -"193" "How would you describe the cellularity and the background matrix in this image?" "Hypercellular with scant stromal component and little background matrix" "Hypocellular with a prominent myxoid background matrix" "Hypercellular with abundant stromal component" "Hypocellular with dense fibrotic background matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/193.jpg" -"194" "What is the predominant staining pattern observed in the neoplastic cells of this tissue section?" "Intense dark brown staining localized to the nucleus" "Strong and diffuse brown staining throughout the cytoplasm" "Patchy staining with a mix of unstained and light brown areas" "Homogeneous light brown staining throughout the cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/194.jpg" -"195" "Which histological feature is evident in the epidermal layer of the skin tissue shown in the image?" "Acantholysis" "Parakeratosis" "Hypergranulosis" "Spongiosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/195.jpg" -"196" "What is the predominant staining characteristic of the collagenous fibers within this connective tissue specimen?" "The fibers predominantly stain green" "The fibers predominantly stain blue" "The fibers predominantly stain pink" "The fibers predominantly stain brown" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/196.jpg" -"197" "Within the tissue section, how would you characterize the vessel that is associated with the lymphoid aggregate?" "The vessel has a thick wall characteristic of a small artery or vein" "The vessel's wall is thin and wispy, common in lymphatic vessels" "The vessel has a thin wall characteristic of a large artery" "The vessel appears dilated with a thinner wall, suggestive of chronic venous insufficiency" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/197.jpg" -"198" "What is the defining cytoplasmic characteristic of the cell labeled (2), which identifies it as a promegakaryocyte?" "Generous amount of blue cytoplasm" "Presence of numerous granules in the cytoplasm" "Dense, darkly-staining cytoplasm" "Scant, lightly-stained cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/198.jpg" -"199" "What does the orientation of the nuclei within these cells suggest?" "There is a consistent polarity to the cells" "The nuclei show normal orientation" "The nuclei demonstrate anisokaryosis" "The nuclei are dyspolaric with disorganized architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/199.jpg" -"200" "Which feature in this image is consistent with the presence of macrophages?" "Large cells with irregularly shaped nuclei" "Cells with slightly larger, pale cytoplasmic areas" "Cells with small, dark-staining nuclei" "Multilobed nuclear morphology" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/200.jpg" -"201" "Based on the morphological appearance of the cells observed in the image, what cellular characteristic is most prominent?" "Cytological atypia with spindle-shaped cells" "Abundant eosinophilic cytoplasm" "Clear or pale cytoplasm" "Hyperchromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/201.jpg" -"202" "What is the arrangement of the neoplastic cells in the image?" "Alveolar or nested pattern" "Glandular pattern" "Sheet-like pattern" "Squamous arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/202.jpg" -"203" "From the tissue organization and cell morphology, what type of epithelium is most likely represented in this image?" "Stratified squamous epithelium" "Glandular epithelium" "Pseudostratified columnar epithelium" "Simple squamous epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/203.jpg" -"204" "What characteristic feature is indicated by the arrow within the vessel?" "Granulomatous inflammation" "Intravascular thrombus" "Cholesterol clefts" "Neutrophilic infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/204.jpg" -"205" "What features suggest an inflammatory response in the surrounding tissue?" "An intact endothelial lining of the vessel" "Hyperchromatic nuclei indicating reactive changes" "Decreased cellularity around the vessel" "Presence of neutrophils around the vessel" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/205.jpg" -"206" "Assuming the image shows a pathological condition, what is the most likely primary event depicted in the vessel?" "Venous thrombosis" "Vasculitis" "Arterial thrombosis" "Atheroembolism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/206.jpg" -"207" "In the provided histological image, what is the predominant tissue structure visible on the right side of the image?" "Loose connective tissue" "Smooth muscle tissue" "Ciliated epithelium" "Dense irregular connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/207.jpg" -"208" "What is the characteristic feature observed in the epidermal layer of the skin section?" "Presence of hyperkeratosis" "Evidence of spongiosis" "Irregular epidermal atrophy" "Thickening of the stratum corneum" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/208.jpg" -"209" "Upon close examination of the basal cells in the epidermis, what change can be observed?" "High mitotic activity" "Basal cell vacuolation" "Hyperchromatic nuclei" "Basal layer hyperplasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/209.jpg" -"210" "What does the eosinophilic, glassy material sporadically distributed throughout the tissue most likely represent?" "Hyaline cartilage" "Collagen bundles" "Amyloid deposits" "Mucosal secretion" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/210.jpg" -"211" "How does the cytoplasm of the larger cells appear in the image?" "Scarce and basophilic" "Abundant and eosinophilic" "Scarce and eosinophilic" "Abundant and basophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/211.jpg" -"212" "What is the predominant cellular morphology observed that suggests an active infection process?" "Red blood cells" "Neutrophils with densely stained nuclei" "Squamous epithelial cells" "Multinucleated giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/212.jpg" -"213" "What cytoplasmic feature is prominent in several cells within this epithelial tissue?" "Pale and foamy cytoplasm" "Multiple lipid droplets" "Dense basophilic granules" "Abundant eosinophilic inclusions" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/213.jpg" -"214" "How would you describe the nuclei of some epithelial cells in this tissue section?" "Exhibiting prominent nucleoli" "Pyknotic with condensed chromatin" "Uniform in size and shape" "Mostly euchromatic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/214.jpg" -"215" "What alteration to nuclear chromatin is evident in this section of epithelial tissue?" "Anisokaryosis (variation in nuclear size)" "Hyperchromasia (increased DNA content)" "Karyolysis (dissolution of the nuclear structure)" "Karyorrhexis (fragmentation of the nucleus)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/215.jpg" -"216" "Considering the tissue architecture and staining pattern, which of the following histopathological features can be reasonably inferred from the image?" "Heterogeneous cell population" "High mitotic activity" "Presence of apoptotic bodies" "Monomorphic cell population" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/216.jpg" -"217" "What characteristic pattern of staining is shown by the T-cells in this CD3 immunostained skin section?" "Cytoplasmic dark brown staining with no evidence of nuclear staining" "Patchy dark brown staining with areas of unstained cytoplasm" "Peripheral rimming with dark brown staining outlining the cells" "Homogeneous dark brown staining throughout the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/217.jpg" -"218" "In which layer of the skin is the highest density of CD3-positive T-cells observed in this image?" "Stratum corneum" "Epidermis" "Papillary dermis" "Reticular dermis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/218.jpg" -"219" "The prominent bulbous structures highlighted in the image predominantly demonstrate which type of staining characteristic?" "Pale eosinophilic staining" "Dark hematoxylin staining" "Homogeneous hematoxylin staining" "Intense eosinophilic staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/219.jpg" -"220" "What features in the image suggest the identification of endothelial cells lining the lumens of microvessels?" "Branched, elongated structures with localised brown staining" "Small, spindled cells without any distinctive staining pattern" "Large, circular cells with central nuclei and clear cytoplasm" "Clusters of round cells with homogenous blue staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/220.jpg" -"221" "What is most indicative of the pathology observed in the epidermal and dermal layers?" "Acantholysis" "Spongiosis" "Subepidermal blistering" "Interface dermatitis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/221.jpg" -"222" "Based on the cellular morphology, which cells are likely present within the inflammatory infiltrate in the dermis?" "Lymphocytes" "Eosinophils" "Neutrophils" "Macrophages" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/222.jpg" -"223" "In comparing the cells inside the inset to those outside it, what is the most evident morphological difference related to the cytoplasm?" "The cells inside the inset show cytoplasm with granular texture" "The cells outside the inset exhibit a higher cytoplasm-to-nucleus ratio" "The cells inside the inset have Cytoplasmic vacuolization" "The cells outside the inset have almost invisible cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/223.jpg" -"224" "What can be inferred about the condition of the cells based on the morphology and staining pattern of the cells with brown cytoplasmic staining?" "The cells represent dysplastic urothelial cells" "The cells suggest urothelial cancer with positive immunoreactivity" "The cells are likely normal urothelial cells undergoing apoptosis" "The cells are indicative of benign urothelial proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/224.jpg" -"225" "What feature is indicated by the arrows in the top layer of the epithelial tissue?" "Normal keratinocyte morphology" "Necrotic keratinocytes with eosinophilic cytoplasm" "Melanocytic proliferation" "Lack of stratum corneum compaction" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/225.jpg" -"226" "What can be inferred about the condition of the basal cell layer?" "Regular arrangement of the stratum basale cells" "Hyperplasia of the stratum basale" "Increase in melanin production" "Detachment and disordering of cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/226.jpg" -"227" "Based on the cellular morphology visible in the region labeled 'B', which statement is correct?" "The cells are chondrocytes residing in a hyaline matrix." "The cells are primarily adipocytes with large lipid droplets." "The cells are osteocytes, evidenced by their encasement within lacunae." "The cells are hepatocytes with prominent central veins." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/227.jpg" -"228" "What is the characteristic appearance of the nuclei in this muscle tissue section?" "Large and central" "Elongated and peripheral" "Round to oval and hyperchromatic" "Multiple and clustered" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/228.jpg" -"229" "Regarding the epithelial layer visible in this image, which statement is accurate?" "The epithelium appears papillary with finger-like projections" "The epithelium is atrophic showing a reduced number of cell layers" "The epithelium shows dyskeratotic cells indicative of apoptosis" "The epithelium is hyperplastic with increased layers of cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/229.jpg" -"230" "By examining the tissue's morphology shown in the image, what can be inferred about the pattern of the collagen present?" "The collagen demonstrates a elastotic pattern typical of elastin degradation" "The collagen displays a hyalinized appearance without the typical wavy pattern" "The collagen shows a reticular pattern consistent with reticulin fibers" "The collagen exhibits a fibrillar structure with prominent cross-linking" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/230.jpg" -"231" "What is the predominant staining color of the collagen fibers in the stroma?" "Blue" "Purple" "Pink" "Red" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/231.jpg" -"232" "Which of the following cellular features does NOT describe the nuclei of the epithelial cells in the image?" "Hyperchromatic" "Enlarged" "Irregularly shaped" "Regularly shaped" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/232.jpg" -"233" "What does the pinkish-red staining of the background stroma suggest about the nature of the tissue?" "Neoplastic cells" "Necrotic tissue" "Connective tissue" "Muscle tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/233.jpg" -"234" "In which panel can moderate cytoplasmic staining intensity be observed, suggesting a moderate expression of FRα?" "Panel A" "Panel D" "Panel C" "Panel B" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/234.jpg" -"235" "Which panel indicates a high level of FRα expression, with deep brown coloration predominantly in the cytoplasm?" "Panel C" "Panel B" "Panel A" "Panel D" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/235.jpg" -"236" "What is the predominant staining characteristic of the cytoplasm in the cells observed under 400x magnification?" "It appears eosinophilic, staining pink to red" "It appears basophilic, staining blue-purple" "It exhibits neutral staining characteristics" "It is unstained and appears transparent" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/236.jpg" -"237" "Assessing the spacing of the nuclei within the stromal compartment adjacent to the duct, what can be determined?" "The nuclei are densely packed with noticeable variation in size." "The nuclei are uniformly dense with rare instances of crowding or atypia." "The nuclei are spaced out evenly, indicating benign characteristics." "The nuclei show mild crowding but no significant atypia." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/237.jpg" -"238" "How would you describe the nuclei of the cells in this image?" "Multinucleated with peripheral margination" "Small and pyknotic with no visible nucleoli" "Hyperchromatic with significant pleomorphism" "Vesicular with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/238.jpg" -"239" "What can be observed about the cell borders in this image?" "Indistinct cell borders with anaplastic features" "Well-defined cell borders with clear cytoplasmic limits" "Cells showing syncytial arrangement without visible borders" "Spindle-shaped cells with indistinct borders" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/239.jpg" -"240" "Based on the arrangement of cells within this tissue, which description is most accurate?" "Solid sheets of uniform cells without stromal invasion" "Glandular formation with complex architectural patterns" "Disorganized growth pattern with infiltrative margins" "Single cells dispersed within a heavily myxoid stroma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/240.jpg" -"241" "What pigment deposition is indicated by the brownish granules observed in the cytoplasm of the proximal tubular epithelial cells?" "Hemosiderin" "Lipofuscin" "Bilirubin" "Melanin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/241.jpg" -"242" "Based on the variable cellular density within the stroma, what pathological process might be occurring?" "Fibrotic changes in the stroma" "Ongoing angiogenesis" "Hydropic degeneration of stromal cells" "Active stromal cell proliferation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/242.jpg" -"243" "What does the extracellular material in this image most likely represent?" "Necrotic cellular debris" "Eosinophilic, homogenous material consistent with stromal components" "Abundant glycogen deposits" "Amyloid deposits" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/243.jpg" -"244" "Based on the nuclear characteristics observed in this microscopic image, which pattern of chromatin distribution is most prevalent?" "Vesicular with prominent nucleoli" "'Salt-and-pepper' pattern of chromatin" "Homogenous with inconspicuous nucleoli" "Open chromatin with distinct nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/244.jpg" -"245" "Assessing the cytoplasmic characteristics in these cells, how would you describe the amount of cytoplasm present surrounding the nuclei?" "Moderate with distinct intercellular spaces" "Copious with abundant intercellular stroma" "Scant with indistinct cell borders" "Abundant with well-defined cell borders" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/245.jpg" -"246" "Analyzing the structural organization of the tissue in this image, which feature is most representative of the arrangement of these neoplastic cells?" "Spindle-shaped cells arranged in a fascicular pattern" "Anisonucleosis with a high degree of cellular pleomorphism" "Tightly packed without much intervening stroma" "Well-differentiated with organized glandular structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/246.jpg" -"247" "What is the predominant morphological characteristic of the large spherical structures visible in the microscopic image?" "Internal septations" "Thick walls and uniform size" "Spiked outer surfaces" "Irregular shapes and sizes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/247.jpg" -"248" "Based on the cellular density and organization observed in the tissue, which of the following descriptions best aligns with the image?" "High cell density with disorganized cellular architecture" "Homogenous distribution of small, well-differentiated cells" "Sparse cellular arrangement with abundant extracellular space" "Regularly organized cells with uniform shapes and sizes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/248.jpg" -"249" "In the image, there is a clear demarcation visible between two regions. What tissues are likely represented by these two distinctly different areas?" "Lymph node and muscle tissue" "Lymph node and tumor tissue" "Tumor tissue and adipose tissue" "Tumor tissue and normal muscle tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/249.jpg" -"250" "Based on the histological features observed at 100x magnification, what is the most likely staining technique used in this section?" "Masson's trichrome staining" "Hematoxylin and eosin (H&E) staining" "Immunohistochemical (IHC) staining for p53 protein" "Periodic acid-Schiff (PAS) staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/250.jpg" -"251" "What can be inferred about the layer of keratinization in the epidermis based on the image?" "It exhibits parakeratosis with retention of nuclei in the stratum corneum" "It indicates atrophy of the stratum corneum with very thin eosinophilic layer" "It shows normal keratinization with a slight eosinophilic hue in the uppermost layer" "It demonstrates hyperkeratosis with a markedly thickened stratum corneum" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/251.jpg" -"252" "Considering the magnification level of the histological section, which of the following structures would not be clearly visible in the dermis?" "Hair follicle structures" "Sweat gland ducts" "Detailed collagen fibers and fibroblasts" "Subcutaneous fat cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/252.jpg" -"253" "Based on the morphological features, what is the likely effect of the silicone droplets on the lymph node tissue architecture?" "The silicone droplets appear to be integrated within the cells, suggesting phagocytosis" "The silicone droplets lead to the formation of multinucleated giant cells around them" "The silicone droplets seem to exert a compressive effect on the surrounding tissue" "There's evidence of reactive hyperplasia adjacent to the droplets" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/253.jpg" -"254" "What is the predominant staining pattern of the targeted antigen as visualized in this tissue section?" "Cytoplasmic staining" "Membranous staining" "No staining visible" "Nuclear staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/254.jpg" -"255" "Based on the morphology of the cells, which tissue origin does this sample most likely represent?" "Mesenchymal tissue" "Muscular tissue" "Epithelial tissue" "Neural tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/255.jpg" -"256" "Analyzing the density and arrangement of cells in this image, which characterization best fits the observed pattern?" "Hypercellularity with a monomorphic pattern" "Areas of both cellularity and spacing without significant pleomorphism" "Hypocellularity with uniform cell spacing" "Hypercellularity with significant pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/256.jpg" -"257" "What is the morphology of the glomerular cells primarily affected by the immunohistochemical staining in this renal tissue image?" "Endothelial cells in the capillary loops" "Tubular epithelial cells" "Podocytes covering the glomerular capillaries" "Mesangial cells within the glomeruli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/257.jpg" -"258" "Assessing the immunohistochemical staining pattern, which feature of the renal tissue is LEAST affected?" "Tubular basement membrane staining" "Interstitial fibrosis" "Capillary loop thickening and hypercellularity" "Prominent mesangial staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/258.jpg" -"259" "In the microscopic view of the renal tissue shown, what cellular characteristic is indicated by the image but is not a dominant feature?" "Distortion of the tubular architecture" "Significant inflammatory infiltrates" "Tubular epithelial cell vacuolation" "Hypercellularity in the glomeruli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/259.jpg" -"260" "Based on the structural organization of the tissue, what type of tumor pathology is suggested?" "Sarcoma" "Leiomyoma" "Adenocarcinoma" "Lymphoma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/260.jpg" -"261" "Based on the presence of the cell layers observed in the image, which type of epithelium lines the cystic structure?" "Simple columnar epithelium" "Stratified squamous epithelium" "Simple cuboidal epithelium" "Pseudostratified ciliated columnar epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/261.jpg" -"262" "What feature distinguishes the periphery of the granuloma from the surrounding tissue?" "A rim of epithelioid cells" "A mononuclear lymphocytic infiltrate" "Presence of multinucleated giant cells" "Necrosis within the granuloma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/262.jpg" -"263" "What can be deduced about the cytoplasmic to nuclear ratio in the cells shown in this tissue section?" "The ratio is decreased, suggesting a high cytoplasmic content" "The ratio is increased, suggesting less prominent nuclei" "The ratio is increased, indicating hypertrophy" "The ratio is decreased, indicating prominent nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/263.jpg" -"264" "Where is the brown MUM1 staining predominantly localized within the cells?" "On the cell surface membrane" "Within the nucleus only" "Within the cytoplasm only" "Both in the nucleus and the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/264.jpg" -"265" "What is the predominant cell type seen in the given tissue section?" "Cuboidal epithelial cells" "Transitional epithelial cells" "Columnar epithelial cells" "Squamous epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/265.jpg" -"266" "What does the cellular heterogeneity observed in the tissue sample suggest?" "Severe dysplasia" "High mitotic activity" "Necrosis" "Mild atypia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/266.jpg" -"267" "Analyzing the striated muscle tissue, which feature most accurately describes the positioning of the nuclei within the muscle fibers?" "Centrally located and clustered" "Peripherally located and clustered" "Centrally located and evenly spaced" "Peripherally located and evenly spaced" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/267.jpg" -"268" "Within the stratum spinosum and stratum granulosum layers, what morphological feature contributes to the reticulated appearance of this tissue section?" "Hypergranulosis with densely stained keratohyalin granules." "Increased melanin deposition within the keratinocytes." "Desmosomal connections giving a spiny appearance to the cells." "Perinuclear vacuolization present in the keratinocytes." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/268.jpg" -"269" "What cellular organization is displayed by the leftmost layer in the image?" "Adipose tissue" "Smooth muscle" "Dense regular connective tissue" "Loose connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/269.jpg" -"270" "Identify the type of cells present in the finger-like projections towards the top right of the image." "Fibroblasts" "Adipocytes" "Columnar epithelial cells" "Squamous epithelial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/270.jpg" -"271" "Based on the tissue morphology, what is the likely origin of the tissue section?" "Renal cortex" "Pulmonary tissue" "Gastric mucosa" "Hepatic parenchyma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/271.jpg" -"272" "What morphological feature of the nuclei is observable in this tissue sample?" "Margination" "Hyperchromatic" "Multinucleation" "Vesicular" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/272.jpg" -"273" "What is the appearance of the interstitial space in this sample?" "Largely acellular without significant features" "Showing vasculitis with fibrinoid necrosis" "Filled with neutrophils" "Infiltrated with mononuclear inflammatory cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/273.jpg" -"274" "Based on the cellular morphology, what is the likely predominant cell type among the small, darkly stained cells scattered throughout the tissue?" "Erythrocytes" "Neutrophils" "Lymphocytes" "Fibroblasts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/274.jpg" -"275" "Identify the clusters of cells indicated by the arrow in the ovarian cortex, which are consistent with a particular cell type?" "Heterophils" "Eosinophils" "Basophils" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/275.jpg" -"276" "What histological feature suggests follicular atresia in the ovarian cortex?" "Presence of large cells with ample cytoplasm and multi-lobed nuclei" "Presence of a highly cellular follicular antrum" "Presence of dense cellular layers within the cortex" "Presence of heterophils associated with follicles" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/276.jpg" -"277" "What histological feature related to tissue damage or reaction is absent in this microscopic field of view?" "Necrosis" "Inflammatory infiltrate" "Mitotic figures" "Hyperchromasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/277.jpg" -"278" "What staining technique does the cytoplasm of the large cell suggest based on its coloration?" "Wright-Giemsa stain" "Periodic acid-Schiff stain" "Acid-fast stain" "Hematoxylin and eosin stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/278.jpg" -"279" "Judging by the appearance of the nucleus, what can be deduced about the chromatin pattern in the large cell?" "The chromatin pattern is dense and homogenous." "There is multiple nucleoli with peripheral margination of the chromatin." "There is a prominent single nucleolus in the nucleus." "It is a hypersegmented nucleus with dispersed chromatin." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/279.jpg" -"280" "Based on the characteristics observed in the image, what is the nucleus-to-cytoplasm ratio of the cells?" "High nucleus-to-cytoplasm ratio" "Uniform nucleus-to-cytoplasm ratio" "Moderate nucleus-to-cytoplasm ratio" "Low nucleus-to-cytoplasm ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/280.jpg" -"281" "What can be inferred about the chromatin distribution within the nuclei of the cells in this image?" "Chromatin exhibits localized clumping" "Chromatin is consolidated to the periphery" "Chromatin distribution is uneven" "Chromatin is evenly distributed" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/281.jpg" -"282" "Which microvascular feature is typical of inflammation as seen in this image?" "The reddish lining of blood vessels within the connective tissue" "The superficial layer that is less dense" "The light blue or greenish hues of collagen fibers" "The increased number of cells with dark-stained nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/282.jpg" -"283" "Based on the image, the features marked with blue asterisks are most consistent with what type of tissue?" "Cardiac muscle" "Dense irregular connective tissue" "Smooth muscle" "Stratified squamous epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/283.jpg" -"284" "What characteristic feature can be observed in the stromal cells of this H&E stained tissue section?" "Stromal cells have a higher nucleus-to-cytoplasm ratio and are more densely packed together" "Stromal cells display a columnar epithelium structure" "Stromal cells contain an abundant, lighter-staining cytoplasm similar to ganglion cells" "Stromal cells are larger than the ganglion cells with prominent nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/284.jpg" -"285" "What is the predominant staining pattern observed in the cells of the tissue?" "Exclusively within the nucleus" "Predominantly at the cell periphery and within the cytoplasm" "Absent in the cells, staining only the extracellular matrix" "Uniformly distributed within the nucleus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/285.jpg" -"286" "Which architectural feature does the tissue exhibit?" "Disorganized, irregular clusters of cells" "Loose, myxoid stromal tissue" "Extensive necrotic debris" "Uniform glandular or tubular structures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/286.jpg" -"287" "How can one describe the cells which can be found within the surrounding interstitium based on their nuclear morphology?" "Cells with large, multinucleated appearances" "Cells with irregular, spindle-shaped nuclei" "Cells with hyperchromatic, pleomorphic nuclei" "Cells with round to oval nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/287.jpg" -"288" "What does the presence of the eosinophilic material within the renal tubules suggest about renal function?" "Indicative of optimal sodium reabsorption" "Indicative of high filtration efficiency" "Suggestive of damage or stress to the renal filtering mechanism" "Suggestive of acute tubular necrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/288.jpg" -"289" "What morphological changes are evident in the rete ridges observed in this skin biopsy sample?" "Elongation and fusion" "Shortening and blunting" "Hypergranulosis and irregular acanthosis" "Atrophy and disappearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/289.jpg" -"290" "Based on the characteristics observed in the glomerular basement membrane, which of the following descriptions is most accurate?" "Thickening with evidence of reduplication" "Presence of spike and dome formations consistent with membranous nephropathy" "Evident thinning suggestive of hereditary nephritis" "Normal thickness without any abnormalities" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/290.jpg" -"291" "Based on the appearance of the vessel, what type of vessel is prominently depicted in this image?" "Artery" "Lymphatic vessel" "Capillary" "Vein" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/291.jpg" -"292" "Considering the intercellular matrix and the staining properties exhibited in this image, what can be inferred about the extracellular environment?" "The intercellular matrix is characterized by intensive staining with multiple colors" "The extracellular matrix does not significantly take up the stain" "There is ample deposition of collagen in the extracellular matrix" "The extracellular matrix is highly reactive to the antibody used" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/292.jpg" -"293" "Based on the nuclear-to-cytoplasmic ratio, which type of cell is most prominent in the surrounding stroma?" "Neutrophils" "Lymphocytes" "Fibroblasts" "Epithelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/293.jpg" -"294" "Considering the pattern of staining in this image, what can be inferred about the targeted antigen within these cells?" "Low level of expression with focal areas of positivity" "High level of expression in the nuclei of the neoplastic cells" "Selective expression in the surrounding stromal tissue" "Heterogeneous expression within the neoplastic cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/294.jpg" -"295" "Considering the shape and organization of the cells in the viewed tissue section, what is the most likely nature of these cells?" "Neoplastic with low-grade dysplasia" "Hyperplastic without atypia" "Neoplastic with high-grade dysplasia" "Metaplastic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/295.jpg" -"296" "Based on the histological features observed, what is the presence of brown staining within some epithelial cells indicative of?" "Hemorrhagic debris" "Immunoreactive material, such as antigens or antibodies" "Calcific deposition" "Lipofuscin accumulation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/296.jpg" -"297" "Based on the immunohistochemistry staining pattern, which characteristic is most indicative of the ductal cells' phenotype?" "Positive staining for estrogen receptors" "Absence of CK20 antigen expression" "High expression of CK20 antigen" "Overexpression of HER2/neu protein" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/297.jpg" -"298" "The morphology of the cells present in the spaces between the ducts most closely resembles which cell type?" "Adipocytes" "Lymphocytes" "Hepatocytes" "Myofibroblastic cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/298.jpg" -"299" "Based on the Hematoxylin and Eosin staining, which white blood cell type is predominantly observed in the subepithelial tissue?" "Basophils" "Neutrophils" "Lymphocytes" "Eosinophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/299.jpg" -"300" "Which of the following describes the appearance of the nuclei within these neoplastic cells provided by the haematoxylin staining in this image?" "Indented and darkly stained" "Uniformly distributed and lightly stained" "Small and round with uniform staining" "Large and clear with faint staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/300.jpg" -"301" "In image A, based on the histological features observed, what is the most likely nature of the central structure seen within the tissue?" "Granuloma with central necrosis" "Adipose tissue cluster" "Nucleus of a single, large cell" "Cross section of a blood vessel" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/301.jpg" -"302" "What characteristic feature does the staining method in image B display to suggest a certain type of bacterial infection?" "Gram-positive cocci in clusters" "Spirochetes" "Acid-fast bacilli" "Gram-negative bacilli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/302.jpg" -"303" "In the image, what does the dark brown color staining indicate in the connective tissue?" "Presence of reticular fibers" "Presence of elastic fibers" "Presence of smooth muscle cells or myofibroblasts" "Presence of collagen fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/303.jpg" -"304" "How can the blood vessel walls within the connective tissue be identified?" "By the elongated and darker staining entities" "By the absence of any specific staining" "By the presence of light-staining round structures" "By the presence of highly vacuolated cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/304.jpg" -"305" "The stained skin tissue section mostly likely represents which level of the epidermal layer?" "Stratum spinosum" "Stratum granulosum" "Stratum corneum" "Stratum basale" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/305.jpg" -"306" "Based on the staining pattern, how does the immunoreactivity for the p53 protein appear in this tissue?" "Strongly positive, with dark staining throughout the tissue" "Heterogeneous, with varying degrees of staining intensity" "Moderately positive, with patchy areas of dark staining" "Negative, with a lack of dark staining indicating non-reactivity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/306.jpg" -"307" "The cells with dark blue nuclei scattered throughout the neuropil are most likely:" "Glial cells" "Endothelial cells" "Red blood cells" "Neuronal cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/307.jpg" -"308" "Based on the presence and morphology of the cells surrounding the elongated space, what is the most probable pathological process occurring in the brain tissue?" "Ischemic stroke" "Acute demyelination" "Inflammatory response" "Gliosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/308.jpg" -"309" "Considering the relative abundance of CD20-positive cells within the tissue matrix, how would you describe their number in comparison to other tissue constituents?" "The CD20-positive cells outnumber the other cells but are not predominant" "The CD20-positive cells are present in moderate numbers" "The CD20-positive cells are the predominant cell type" "The CD20-positive cells are relatively few in comparison to other cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/309.jpg" -"310" "What is the nature of the stromal cell population surrounding the glandular structures?" "Predominantly lymphocytes" "Extensive fibroblastic proliferation" "Dominance of neutrophils" "Predominantly mature adipocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/310.jpg" -"311" "Analyzing the architecture of the glandular structures, how would you describe their formation?" "Cystically dilated with irregular shapes" "Uniformly sized and well-organized" "Varied in size with opportunistic growth patterns" "Regular papillary formations with fibrovascular cores" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/311.jpg" -"312" "What morphological feature is evident in the right-side glomerulus of the kidney tissue?" "Widespread mesangial expansion" "Evidence of global glomerulosclerosis" "Uniformly thin basement membranes" "Segmental sclerosis with a crescent formation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/312.jpg" -"313" "Analyzing the kidney tissue, which statement is true regarding the surrounding tubular structures?" "There is significant dilation of the tubules with flattening of the tubular epithelium" "Tubular atrophy and interstitial fibrosis are present" "No overt signs of tubular injury are visible" "Tubules exhibit intraluminal proteinaceous casts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/313.jpg" -"314" "What characteristic feature of the nuclei can be observed in the cells of this tissue section?" "They exhibit anisonucleosis" "They display karyolysis" "They exhibit monomorphism" "They are hypochromatic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/314.jpg" -"315" "Based on the image, how has the connective tissue matrix responded to the parasitic infection?" "It shows increased adipose tissue infiltration." "It displays a basophilic staining pattern indicative of DNA-rich regions." "It exhibits an eosinophilic staining pattern typical of a collagenous matrix." "It has become hyperchromatic and densely packed." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/315.jpg" -"316" "Based on the glandular architecture observed, what is the most likely nature of the neoplastic process?" "Well-differentiated" "Moderately differentiated" "Poorly differentiated" "Anaplastic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/316.jpg" -"317" "What does the presence of eosinophilic and basophilic secretions within the cells suggest?" "Presence of inflammation and immune response" "Indication of benign glandular activity" "Evidence of high lipid content within cells" "Suggestion of neoplastic mucin production" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/317.jpg" -"318" "By examining the glomerular structure, what is the most likely observation regarding mesangial expansion?" "Mesangial expansion is present but does not severely encroach on the capillary lumens" "Mesangial expansion is conspicuously encroaching on capillary lumens" "Mesangial expansion completely obliterates the capillary lumens" "No mesangial expansion" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/318.jpg" -"319" "Based on the appearance of the tubular structures surrounding the glomerulus, which statement is most accurate?" "Intratubular casts are prominently present" "Tubular dilation is extensively observed" "There is marked tubular atrophy" "The tubules show no significant pathological changes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/319.jpg" -"320" "Evaluating the presence of mesangial matrix or cellularity is crucial in assessing glomerular health. Which observation from this image most accurately represents the mesangial status?" "Hypercellularity within the glomerular capillaries" "No evidence of mesangial expansion" "Decrease in mesangial matrix" "Constriction of the capillary space due to mesangial expansion" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/320.jpg" -"321" "Based on the main image, what is the predominant characteristic of the nuclei within the inflammatory infiltrate?" "Basophilic staining and heterogeneity in size and shape" "Absence of any visible nuclei due to high levels of tissue necrosis" "Uniformly small and hyperchromatic staining" "Predominantly large and pale staining with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/321.jpg" -"322" "Based on the cytoplasmic characteristics observed in the image, which description most accurately fits the cytoplasm of these cells?" "The cytoplasm is abundant and eosinophilic" "The cytoplasm is sparse and basophilic" "The cytoplasm is filled with large vacuoles" "The cytoplasm is dense and contains multiple nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/322.jpg" -"323" "What feature of the nuclei in this microscopic image is indicative of a high nucleus-to-cytoplasm ratio?" "Uniform, small-sized nuclei" "Nuclei with centralized chromatin" "Hyperchromatic nuclei with variable sizes" "Large nuclei with ample cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/323.jpg" -"324" "Based on the cellular architecture, what type of histological pattern do the rounded tumor cells present within the image most closely resemble?" "Renal glomeruli-like structures" "Hepatic trabeculae-like arrays" "Pulmonary alveoli-like formations" "Adipose tissue-like clusters" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/324.jpg" -"325" "Based on the staining pattern observed in the image, which component of the tissue is predominantly targeted by the immunohistochemical staining?" "The basement membrane of the glandular epithelium" "The cell nuclei in glandular cells" "The extracellular matrix/connective tissue" "The cell cytoplasm in glandular cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/325.jpg" -"326" "Based on the histological features in this image, which type of cells is interspersed among the vacuolated cells?" "Fibroblasts" "Epithelioid cells" "Multinucleated giant cells" "Lymphocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/326.jpg" -"327" "What pattern does the nuclear chromatin of the epithelioid cells exhibit in this image?" "Peripheral margination" "Vesicular with multiple nucleoli" "Homogenous and dense" "Stippled or 'salt and pepper'" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/327.jpg" -"328" "Based on the staining patterns observed, which of the following cellular components are predominantly highlighted by the brown color in this image?" "Cytoplasm" "Cell membrane" "Nuclei" "Extracellular matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/328.jpg" -"329" "What level of nuclear pleomorphism is visible in the cells?" "Mild pleomorphism with slight variations in nuclear size and shape" "Marked pleomorphism with significant variation in nuclear size and shape" "Virtually no pleomorphism; nuclei are uniform in size and shape" "Moderate pleomorphism with an appreciable variety in size and shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/329.jpg" -"330" "How would you describe the chromatin pattern in the nuclei?" "Slight variation with most nuclei showing a similar chromatin pattern" "Uniform chromatin distribution with no visible variation between nuclei" "Moderate variation with an equal mix of fine and condensed chromatin patterns" "Marked variation with a distinct difference between nuclei showing fine and condensed chromatin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/330.jpg" -"331" "What best describes the content within the hepatocytes that the arrows point to?" "Bile pigment accumulation" "Mallory bodies" "Glycogen deposits" "Lipid vacuoles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/331.jpg" -"332" "What is the predominant cell type observed in the microscopic image?" "Lymphocytes" "Squamous cells" "Adipocytes" "Spindle cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/332.jpg" -"333" "Considering the density of the background matrix of the tissue, what feature can be noted?" "High cellularity" "Low cell density" "Heavy collagen deposition" "Necrotic debris" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/333.jpg" -"334" "Based on the nuclear staining pattern, what cellular activity is primarily represented by the sparse ki-67-positive nuclei?" "Senescence" "Active proliferation" "Quiescence" "Apoptosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/334.jpg" -"335" "What does the stroma surrounding the cystic spaces tell us about the potential aggressiveness of the tissue observed in the image?" "Dense, fibrous stroma indicates a benign process" "The presence of stroma is unrelated to malignancy" "Abundant stroma suggests a higher likelihood of malignancy" "Sparse stroma could correlate with non-aggressive behavior" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/335.jpg" -"336" "What is the predominant histological feature observed in this lung tissue section?" "Patchy areas of dense collagenous fibrous tissue indicating fibrosis" "Large areas of neoplastic cell growth with atypical nuclei" "Presence of granulomas with multinucleated giant cells" "Normal alveolar architecture with clear alveolar spaces" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/336.jpg" -"337" "What does the presence of the pink to purple amorphous material in the stroma suggest?" "Collagen deposition" "Necrosis" "Hemorrhage" "Acute inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/337.jpg" -"338" "Which image demonstrates the cellular morphology and tissue architecture consistent with neuroendocrine cells based on the Hematoxylin and Eosin (H&E) staining technique?" "Image D" "Image A" "Image B" "Image C" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/338.jpg" -"339" "Based on the Ki-67 immunohistochemical staining technique, which image would indicate a need for enhanced contrast to improve visualization for quantification purposes?" "Image A" "Image C" "Image D" "Image B" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/339.jpg" -"340" "Which image indicates a high nuclear expression of the target antigen across the tumor cells, consistent with a high rate of cellular proliferation?" "Image D" "Image C" "Image B" "Image A" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/340.jpg" -"341" "Based on the pigmented macrophages observed in panel A, what is the granular material they contain?" "Iron deposits" "Hematoxylin" "Lipofuscin" "Neuromelanin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/341.jpg" -"342" "Based on the structural features observed, what conclusion can be drawn about the differentiation of this tissue?" "There is a clear formation of fibrous connective tissue" "The tissue architecture lacks uniformity and organization" "The tissue exhibits well-organized glandular structures" "Squamous differentiation is apparent in the cell morphology" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/342.jpg" -"343" "Considering the overall structure and components visible in the microscopic image, which part of the body does the tissue section most likely originate from?" "Cortical area of the brain" "Epidermal layer of the skin" "Inner mucosal lining of the gastrointestinal tract" "Fibrous structure such as a tendon" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/343.jpg" -"344" "Upon examination of the tissue section, what do the areas of differing cell density suggest?" "Normal lung tissue architecture" "Disorganized growth patterns" "An active inflammatory process" "High level of tissue organization" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/344.jpg" -"345" "What can be inferred about the largest cell in the image regarding the distribution of chromatin within its nucleus?" "The chromatin appears hyperchromatic with condensed areas" "The chromatin is uniformly dispersed throughout the nucleus" "The chromatin is marginated along the nuclear membrane" "The chromatin exhibits a clear nucleolus with surrounding halo" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/345.jpg" -"346" "Based on the staining pattern, what can be said about the potential use of the stain in this microscopic image?" "The stain seems to be specific for elastic fibers" "The stain may be a silver-based reticulin stain" "The stain is possibly a hematological stain like Giemsa" "The stain is likely a lipid-soluble stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/346.jpg" -"347" "What is the defining characteristic of the large cells observed at the center of the image?" "Absence of any nuclei" "Presence of a single, large central nucleus" "Uniform size and shape of the nuclei" "Multiple nuclei scattered throughout the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/347.jpg" -"348" "What histological feature is indicated by the arrows in the image?" "Cellular infiltration of lymphocytes" "Amyloid deposits" "Collagen bundles" "Fibrinoid necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/348.jpg" -"349" "What is the morphology of the glomerular capillaries as observed in this renal biopsy stained with H&E?" "Capillaries with patent lumens" "Presence of crescent formation" "Capillary walls exhibit double contouring" "Capillary walls with significant thickening" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/349.jpg" -"350" "How does the organization of the spindle cells within the tissue section help distinguish this lesion?" "The spindle cells are arranged in well-organized fascicles" "The spindle cells align in a highly organized storiform pattern" "The spindle cells are arranged loosely in a disorganized pattern" "The spindle cells form solid sheets with no discernible organizational pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/350.jpg" -"351" "Based on the hepatocyte morphology, what change is evident in the cytoplasm of multiple hepatocytes?" "Foamy degeneration" "Glycogen depletion" "Lipid droplet accumulation" "Hydropic swelling" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/351.jpg" -"352" "In this liver tissue sample, what is notably absent that would indicate alteration in microarchitecture?" "Intact hepatocyte cords" "Normal sinusoidal structure" "Visible central veins" "Portal triads" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/352.jpg" -"353" "In terms of cytoplasmic features, how does the large cell (indicated by the arrow) differ from the surrounding smaller cells?" "The cytoplasm of the large cell is deeply basophilic with scattered inclusions, unlike the smaller cells." "The cytoplasm of the large cell is scant and eosinophilic, while the smaller cells have abundant basophilic cytoplasm." "The large cell contains multiple vacuoles while the smaller cells feature high levels of glycogen." "The smaller cells show deeply eosinophilic cytoplasm compared to the pale basophilic large cell." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/353.jpg" -"354" "What is the predominant feature of the large cells indicated by the arrows in this histopathologic image?" "Multiple, centrally located nuclei" "Single, centrally located nucleus" "Single, eccentrically located nucleus" "Multiple nuclei with a peripheral arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/354.jpg" -"355" "Based on the image, how would you characterize the cytoplasm of the large multinucleated cells?" "Basophilic with sparse granules" "Eosinophilic and abundant" "Eosinophilic with abundant granules" "Basophilic and scant" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/355.jpg" -"356" "Based on the characteristics of the intracellular rod-shaped structures in this image, what staining technique was most likely used?" "Acid-fast stain" "Gram stain" "Giemsa stain" "Wright's stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/356.jpg" -"357" "How would you describe the nuclear-to-cytoplasmic ratio in the cells depicted in the image?" "Inconspicuous nuclei with abundant cytoplasm" "High nuclear-to-cytoplasmic ratio" "Nuclei and cytoplasm are equally distributed" "Low nuclear-to-cytoplasmic ratio" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/357.jpg" -"358" "Based on the staining characteristics seen in the image, what is the HER2 score that can be inferred?" "HER2 score of 0" "HER2 score of 1+" "HER2 score of 2+" "HER2 score of 3+" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/358.jpg" -"359" "What is the predominant cell type observed in the connective tissue underlying the epithelium?" "Adipocytes" "Fibroblasts" "Lymphocytes" "Chondrocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/359.jpg" -"360" "Which feature best describes the organization of the cells observed within this tissue sample?" "Disorganized structure with evident hypercellularity" "Haphazard arrangement with significant cellular overlapping" "Uniform distribution with a lobulated contour" "Random orientation with a loss of architecture" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/360.jpg" -"361" "Regarding the visual characteristics of capillary loops in the image, what observation is most accurate?" "The capillary loops are obscured and difficult to discern" "Capillary loops maintain a delicate and orderly arrangement" "There is extensive capillary looping with tortuous vessels" "Capillary loops are markedly dilated with evidence of aneurysm formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/361.jpg" -"362" "Assessing the cells for signs of atypia or malignancy, which of the following is a correct observation from the image?" "Cells exhibit significant pleomorphism and hyperchromasia" "There is an absence of nuclear atypia and malignant features" "Necrosis is present throughout the sample, suggesting high-grade malignancy" "Cells display numerous mitotic figures indicative of high proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/362.jpg" -"363" "What type of cellular arrangement predominates in the image provided?" "Well-formed nerve bundles" "Ordered parallel arrays of fibrous tissue" "Pseudoonion bulb formations" "Random orientation of collagen bundles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/363.jpg" -"364" "Which of the following best characterizes the nuclei observed in this histological section?" "Sparse and elongated" "Numerous and hyperchromatic" "Abundant with abnormal mitotic figures" "Rounded and with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/364.jpg" -"365" "Based on the cellular organization observed in the image, which descriptive term best relates to the tissue type present?" "Simple columnar epithelium" "Stratified squamous epithelium" "Transitional epithelium" "Pseudostratified columnar epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/365.jpg" -"366" "What is the most likely identity of the centrally located cellular structure in the image?" "Skeletal muscle fiber" "Large nerve fiber" "Lymphatic channel" "Blood vessel" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/366.jpg" -"367" "Which of the following best describes the morphology of the glandular structures surrounding the nerve?" "Round with a single layer of epithelium" "Tubular with centrally located nuclei" "Irregularly shaped with pleomorphic nuclei" "Uniformly shaped with small, regular nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/367.jpg" -"368" "Based on the features observed in the stratum corneum, which of the following abnormalities can be identified?" "Hypergranulosis" "Parakeratosis" "Acanthosis" "Hyperkeratosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/368.jpg" -"369" "Assessing the overall architecture of the epithelium, what can be inferred about its organization?" "Presence of typical granular cell layer" "Disordered arrangement of keratinocytes" "Uniform and structured arrangement of keratinocytes" "Thickening of the stratum lucidum" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/369.jpg" -"370" "What predominant nuclear feature can be observed in this microscopic image?" "Hyperchromatic nuclei" "Mononucleolated nuclei" "Uniformly shaped and sized nuclei" "Vesicular nuclei with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/370.jpg" -"371" "When examining the interstitial tissue in the image, which of the following conditions is not observed?" "Lack of visible necrosis" "Significant expansion of the interstitium" "Presence of inflammatory cell infiltrates" "Absence of extensive fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/371.jpg" -"372" "How would you describe the distribution of the positively stained cells in this tissue section?" "Polarized distribution" "Clustered distribution" "Uniform distribution" "Random distribution" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/372.jpg" -"373" "Focusing on the darkly stained cell clusters in the dermis, what immunohistochemical marker are these cells likely positive for, based on their pattern of infiltration?" "CD20, indicating a B-cell lineage" "CD3, a T-cell marker" "CD68, suggestive of macrophages" "Factor VIII, related to endothelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/373.jpg" -"374" "Considering the irregular connective tissue observed in the dermis and the scattered cellular infiltrate, what potential dermatological condition could this tissue sample represent?" "Psoriasis, characterized by neutrophilic infiltrate and dilated blood vessels" "Cutaneous lupus erythematosus, often associated with interface dermatitis and basement membrane thickening" "Lichen planus, characterized by a band-like lymphocytic infiltrate" "Atopic dermatitis, typically associated with spongiosis and eosinophilic infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/374.jpg" -"375" "What characteristic feature of the stratum corneum can be observed in this section of skin?" "Uniform cell size and shape with no nuclear retention" "Hyperkeratosis with a thickened stratum corneum" "Retained nuclei indicating parakeratosis" "Abundant keratohyalin granules" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/375.jpg" -"376" "What feature can be inferred about the underlying dermis based on the observed morphology?" "Dense infiltration by atypical cells" "Necrotizing granulomatous inflammation" "Abundant collagen deposition with fibrosis" "Presence of clear spaces suggesting edema" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/376.jpg" -"377" "How would you describe the arrangement of the spindle cells within the matrix?" "Monotonously distributed with minimal variation" "Haphazard without a discernible pattern" "Forming structured, well-defined nests" "Highly organized and parallel" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/377.jpg" -"378" "In panel a, what is the predominant localization of the brown staining indicative of?" "Nuclear and cytoplasmic protein expression" "Extracellular matrix protein deposition" "Cytoplasmic and membranous protein expression" "Endothelial cell marker expression" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/378.jpg" -"379" "What histopathological feature can be observed within the epidermal layer of this tissue section?" "Parakeratosis" "Acanthosis" "Hypergranulosis" "Acantholysis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/379.jpg" -"380" "Which glomerular cell type appears hypertrophied in this renal biopsy sample?" "Mesangial cells" "Endothelial cells" "Podocytes" "Parietal cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/380.jpg" -"381" "Based on the chromatin pattern of the cells indicated by the blue arrow, what is the most likely diagnosis?" "Hepatocellular carcinoma cells" "Neuroendocrine tumor cells" "Serous cystadenoma cells" "Squamous cell carcinoma cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/381.jpg" -"382" "What feature indicated by the blue arrow is consistent with neuroendocrine tumor cells?" "Nucleoli present at the nuclear membrane" "'Salt and pepper' chromatin pattern" "Multi-nucleation" "Presence of intranuclear cytoplasmic inclusions" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/382.jpg" -"383" "Based on the cellular morphology, which layer of stratified squamous epithelium is most prevalent on the left side of the image?" "Spinous layer" "Basal layer" "Granular layer" "Keratin layer" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/383.jpg" -"384" "What does the appearance of the nuclei in the stratified squamous epithelium suggest?" "The tissue is healthy with no visible sign of atypia" "There is potential dysplasia within the epithelium" "The nuclei depict signs of pyknosis" "The cells are undergoing normal mitosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/384.jpg" -"385" "How would you describe the quantity and appearance of the cytoplasm in the cells in this histological slide?" "Moderate amount of basophilic cytoplasm" "Abundant cytoplasm with multiple vacuoles" "Scant to moderate cytoplasm that is pale in staining" "Abundant eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/385.jpg" -"386" "What does the presence of cells with dark brown staining in their cytoplasm or perinuclear regions likely indicate in this tissue sample?" "Lipid storage within the cells" "Degeneration of cellular components" "Positive immunohistochemical labeling for a specific antigen" "Accumulation of pigmented substances" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/386.jpg" -"387" "Analyzing the stroma visible in the image, which of the following statements is accurate?" "The pink-staining stroma suggests dense connective tissue without malignant characteristics" "The stroma is undifferentiated with clear evidence of organized glandular formation" "There is a loss of normal architecture and lack of clear tissue structure" "The stroma appears to support an inflammatory process rather than a neoplastic one" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/387.jpg" -"388" "Based on the orientation of the nuclei within the columnar epithelial cells, how are they aligned relative to the basement membrane?" "Clumped together without discernible orientation" "Randomly distributed without a uniform orientation" "Oriented perpendicular to the basement membrane" "Oriented parallel to the basement membrane" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/388.jpg" -"389" "What is the characteristic nature of the cytoplasm within the columnar epithelial cells?" "Basophilic and heterogeneous" "Basophilic and homogenous" "Eosinophilic and homogenous" "Eosinophilic and heterogeneous" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/389.jpg" -"390" "What feature is primarily observed on the operculated end of the oval structures?" "A concave indentation" "A distinct spike" "A significant flattening" "A bulge or slight protrusion" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/390.jpg" -"391" "How would you describe the internal content of the oval structures?" "Granular or lumpy" "Homogeneously eosinophilic" "Largely clear or empty" "Uniformly basophilic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/391.jpg" -"392" "Considering the uniform size of the structures, what would be an appropriate estimation of their diameter?" "Approximately 10-20 micrometers" "Approximately 80-100 micrometers" "Approximately 30-40 micrometers" "Approximately 50-70 micrometers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/392.jpg" -"393" "What does the configuration of cells within the center of this tissue specimen suggest?" "A benign aggregation of uniform cells" "Normal lymphoid follicular architecture" "A cluster of atypical cells indicative of a tumor embolus" "A granulomatous inflammatory response" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/393.jpg" -"394" "The cells lining the space around the cluster of atypical cells generally have which of the following characteristics?" "Small, round, and darkly stained nuclei with scant cytoplasm" "Multinucleation with granular cytoplasm" "Flattened cells with elongated nuclei" "Large vesicular nuclei with prominent nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/394.jpg" -"395" "Based on the histological features observed in the hepatic tissue, what does the labeled structure 'P' most likely represent?" "Hepatic artery" "Central vein" "Sinusoid" "Portal vein" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/395.jpg" -"396" "What tissue abnormality can be inferred from the presence of pale areas within the section?" "Hemorrhage due to extracellular blood leakage." "Hypomyelination due to a loss or reduction of myelin content." "Hypercellularity due to increased proliferation." "Necrosis due to tissue death and breakdown." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/396.jpg" -"397" "When assessing the stromal component in this tissue sample, what predominate feature can be seen in the provided image?" "High vascular proliferation" "Dense collagen bundles" "Moderate amount of connective tissue" "Abundant adipose tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/397.jpg" -"398" "Which histological background finding supports the diagnosis of a high-grade malignancy?" "Eosinophilic and homogeneous background" "Lipid-rich and hemorrhagic background" "Eosinophilic and hemorrhagic background" "Basophilic and hemorrhagic background" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/398.jpg" -"399" "Based on the histological features observed, what change is predominantly seen in the hepatocytes around the central vein?" "Glycogen depletion" "Bile accumulation" "Lipid accumulation" "Hydropic swelling" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/399.jpg" -"400" "In the surrounding tissue, which layer of the skin appears to be represented by the acellular areas with abundant extracellular matrix?" "The stratum corneum, distinguished by anucleated, keratinized cells" "The hypodermis, characterized by sparse cellular elements and extracellular matrix" "The epidermis, which normally shows stratified squamous epithelial cells" "The dermis, typically containing dense irregular connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/400.jpg" -"401" "Based on the hematoxylin and eosin staining of the cells, which descriptor best fits the cytoplasmic staining intensity of the cells?" "Neutrophilic - pale staining" "Amphophilic - a mix of blue and pink" "Basophilic - deep blue" "Eosinophilic - dense purple" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/401.jpg" -"402" "What is the predominant nuclear morphology observed in the cells within this microscopic image?" "Round nuclei with evenly distributed chromatin" "Hypersegmented nuclei with condensed chromatin" "Clefted nuclei with multiple nucleoli" "Irregular nuclei with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/402.jpg" -"403" "Based on the cell morphology, what is the cytoplasmic appearance of the cells in this image?" "Moderate to abundant cytoplasm with basophilic staining" "Vacuolated cytoplasm with distinct cell boundaries" "Scant cytoplasm with indistinct cell boundaries" "Abundant cytoplasm with distinct cell boundaries" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/403.jpg" -"404" "Scattered darker-stained areas within the cellular matrix might represent which of the following pathological features?" "Necrosis or in situ hybridization signals" "Fibrous tissue deposition" "Lipid-laden macrophages" "Calcifications" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/404.jpg" -"405" "Observing the cellular arrangement in panel b, what type of structure formation is depicted?" "Single-file linear arrangement without lumen formation" "Disorganized clusters without any discernible structure" "Solid nests with peripheral palisading" "Glandular structure with a central duct lined by multiple layers of cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/405.jpg" -"406" "Based on the cellular morphology and tissue architecture in both panels, which of the following features is NOT observed in the provided tissue samples?" "Prominent nucleoli" "Squamous differentiation" "Papillotubular architecture" "Clear cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/406.jpg" -"407" "The cellular formation visible in this microscopic image lacks which of the following characteristics typically found in benign lesions?" "Presence of mitotic figures" "Uniformity of cell size" "Well-defined boundaries" "High nucleus-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/407.jpg" -"408" "How would you describe the nuclear-to-cytoplasmic ratio in the cells within the image?" "Low nuclear-to-cytoplasmic ratio" "Moderate nuclear-to-cytoplasmic ratio" "Inconsistent nuclear-to-cytoplasmic ratio across cells" "High nuclear-to-cytoplasmic ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/408.jpg" -"409" "What is the predominant cellular feature within the large, central circular structure?" "Predominantly lymphocytic infiltration" "Dense aggregation of spore-like inclusions" "Conspicuous nucleoli within the cells" "Multinucleated giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/409.jpg" -"410" "What best describes the architectural arrangement of the mucosal cells surrounding the large central structure?" "Cells arranged in a well-defined glandular pattern" "Mucosal cells with eosinophilic cytoplasm and basally located nuclei" "Loosely dispersed cells without a distinct pattern" "Highly pleomorphic cells with numerous mitotic figures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/410.jpg" -"411" "Is there evidence of an inflammatory response in the vicinity of the large, circular structure?" "Presence of granulomatous inflammation" "No visible inflammatory response in the immediate vicinity" "Extensive infiltration of neutrophils around the structure" "Lymphoid aggregates surrounding the structure" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/411.jpg" -"412" "Based on the cellular morphology visible in the image, what is the characteristic feature seen in the hepatocytes?" "Hyperchromatic nuclei" "Multiple small cytoplasmic vacuoles" "Single large cytoplasmic vacuole displacing the nucleus" "Dense eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/412.jpg" -"413" "What histological feature is evident in the sinusoidal areas of the liver tissue?" "Megalocytosis" "Peliosis hepatis" "Mixed inflammatory cell infiltrate" "Fibrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/413.jpg" -"414" "What is the predominant cellular characteristic of the large, central structures marked with asterisks?" "Necrotic debris" "Multinucleated giant cells" "Hyperchromatic nuclei" "Simple squamous epithelium lining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/414.jpg" -"415" "What is the predominant type of cells lining the central cystic structure?" "Squamous epithelial cells" "Columnar epithelial cells" "Cuboidal epithelial cells" "Transitional epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/415.jpg" -"416" "What type of substance fills the central cystic structure?" "Necrotic debris" "Eosinophilic keratin material" "Serous fluid" "Mucoid material" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/416.jpg" -"417" "Within the cytoplasm of the plasma cells shown in the image, you can observe a clear zone. What does this zone correspond to?" "Golgi apparatus" "Lipid droplet" "Endoplasmic reticulum" "Mitochondrial accumulation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/417.jpg" -"418" "What histological feature of the section is evident toward the right, distinguishable from the plasma cells due to its distinctly elongated nuclei and parallel fibers?" "Connective tissue" "Epithelial tissue" "Smooth muscle tissue" "Nerve tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/418.jpg" -"419" "Which statement accurately describes the immune response in the surrounding stroma, as evidenced by cellular infiltration?" "Minimal cellular infiltration is observed, suggesting a limited inflammatory response" "Eosinophilic infiltration is prominent, indicating an allergic reaction" "Dense lymphocytic infiltration is present, indicating a robust immune response" "Neutrophilic infiltration suggests an acute inflammatory response" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/419.jpg" -"420" "Based on the immunohistochemical staining seen in the image, what is the most likely antibody that has been used to target antigenic sites within these cells?" "Anti-CD3 antibody" "Anti-CD20 antibody" "Anti-Melan A antibody" "Anti-cytokeratin antibody" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/420.jpg" -"421" "Observing the staining pattern, what can be inferred about the type of cells predominantly present in the image?" "Epithelial cells" "Fibroblasts" "Lymphocytes" "Melanocytes or melanoma cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/421.jpg" -"422" "How would you describe the nuclear morphology of the mononuclear cells seen in this image of a giant cell tumor of bone?" "Oval to spindle-shaped nuclei with dense chromatin" "Round nuclei with prominent nucleoli" "Hypersegmented nuclei with dense chromatin" "Smudged nuclei with loss of nuclear detail" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/422.jpg" -"423" "How would you describe the appearance of the blood vessel's wall in relation to the surrounding tissue?" "Thin and poorly defined" "Infiltrated with inflammatory cells" "Thickened with disrupted architecture" "Well-defined with centralized lumen" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/423.jpg" -"424" "What is the cytoplasmic appearance of the cells indicated by arrows in this microscopic image?" "Clear and devoid of any staining" "Homogeneously eosinophilic" "Vacuolated with a fine granular texture" "Foamy with a blue-black coloration" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/424.jpg" -"425" "What is the most likely staining technique used for this microscopic image based on the observable characteristics of the cells?" "Hematoxylin and eosin (H&E)" "Wright stain" "Gram stain" "Sudan black" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/425.jpg" -"426" "Assuming the purple-stained structures are indicative of a bacterial presence, what is the most likely arrangement of these bacteria seen in the image?" "Bacilli in pairs" "Staphylococci clusters" "Streptococci chains" "Diplococci pairs" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/426.jpg" -"427" "Based on the observed tissue morphology, what is the predominant shape of the cells?" "Columnar" "Spherical" "Spindle-shaped" "Polygonal" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/427.jpg" -"428" "Based on the image, what type of cells predominantly line the lumen visible at the center?" "Endothelial cells" "Smooth muscle cells" "Squamous epithelial cells" "Transitional epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/428.jpg" -"429" "Which of the following best describes the appearance of the nuclei in the observed cells?" "The nuclei are large with a prominent perinuclear halo." "The nuclei exhibit a clear nucleolus with dispersed chromatin." "The nuclei are small and hyperchromatic with irregular shapes." "The nuclei are round to oval with condensed chromatin." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/429.jpg" -"430" "Based on the image, how would you characterize the staining affinity of the cytoplasm of the observed cells?" "Basophilic, showing an affinity for basic dyes" "Eosinophilic, staining readily with acid dyes" "Amphiphilic, staining equally with both acid and basic dyes" "Neutrophilic, with no particular affinity for either acid or basic dyes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/430.jpg" -"431" "What does the area at the top of the image most likely represent, based on its morphology?" "Glomerular hypercellularity" "Tubular microabscess" "Healthy tubular epithelium" "Podocyte effacement" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/431.jpg" -"432" "What is the predominant cell shape observed in the tissue section?" "Cuboidal" "Columnar" "Round" "Spindle-shaped" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/432.jpg" -"433" "What type of matrix is exhibited between the spindle cells in this tissue sample?" "Myxoid" "Dense collagenous" "Osteoid" "Elastic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/433.jpg" -"434" "Based on the morphology of the cells observed in the image, what type of cellular shape predominates?" "Cuboidal-shaped cells" "Polygonal-shaped cells" "Round to oval-shaped cells" "Spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/434.jpg" -"435" "What architectural feature is observed in the tissue sample?" "Distinct tubular formations" "Regular glandular structures" "Scant extracellular matrix" "Copious extracellular matrix with hyalinization" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/435.jpg" -"436" "Which characteristic feature denotes the atrophy of muscle fibers in this image?" "The fibers that exhibit a rounded morphology" "The muscle fibers pointed out by tailed arrows" "The space between fibers marked with a star symbol" "The overall uniformity in the size and shape of the muscle fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/436.jpg" -"437" "Consider the staining properties of the cells in the image. What can be inferred about the darker-staining areas within the tubular structures?" "These darker-staining areas are artifacts of staining and not indicative of actual cellular structures" "These darker-staining areas represent cell nuclei that are active in protein synthesis" "These darker-staining areas indicate regions of necrosis within the tubules" "These darker-staining areas reflect the presence of secretory products within the tubules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/437.jpg" -"438" "How would you describe the nuclei within the neoplastic cellular islands in the image?" "Hyperchromatic and pleomorphic" "Vesicular with prominent nucleoli" "Uniform with fine chromatin" "Multinucleated with smudged chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/438.jpg" -"439" "Based on the cellular morphology, which cell type can be primarily identified in this image?" "Hepatocytes" "Cardiomyocytes" "Neuronal cells" "Squamous epithelial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/439.jpg" -"440" "What does the presence of smaller, denser nuclei in focal to multifocal areas within the image most likely indicate?" "Necrosis" "Hyperplasia" "Neoplasia" "Inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/440.jpg" -"441" "In panel (a) of the image, which of the following best describes the distribution of inflammatory cells within the dermis?" "Scattered diffusely throughout the dermis" "Clustered around hair follicles" "Focused at the dermal-epidermal junction" "Confined to the perivascular regions" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/441.jpg" -"442" "What is the predominant feature of the extracellular matrix in the cartilage tissue as observed under the microscope?" "Homogeneous basophilic staining" "Variegated basophilic and eosinophilic staining" "Acellular eosinophilic zones" "Homogeneous eosinophilic staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/442.jpg" -"443" "What does the cellular arrangement in the cartilage tissue suggest?" "Varied distribution with regions of closely packed and sparse cells" "Uniform distribution with hyaline matrix" "Disorganized clusters in a myxoid matrix" "Uniformly dispersed cells in a fibrous matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/443.jpg" -"444" "What tissue characteristic can be observed at the location indicated by the orange arrow in the image?" "Multilayered squamous cells" "Keratinized stratified epithelium" "Transitional epithelium" "Pseudostratified columnar epithelium with cilia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/444.jpg" -"445" "What do the structures highlighted by the yellow arrow represent?" "Bronchial glands with clustered acini" "Cluster of hepatocytes forming a liver lobule" "Acinar units of a salivary gland" "Alveolar sacs in the lung" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/445.jpg" -"446" "Based on the microscopic image of the tissue section, which description best fits the arrangement of the cells observed?" "Cells organized in tightly packed clusters" "Cells aligned in a single layer with a brush border" "Cells dispersed in a loose, irregular pattern" "Cells arranged in interwoven fascicles" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/446.jpg" -"447" "What is the morphology of the cell nuclei according to the microscopic image?" "Hypersegmented nuclei without nucleoli" "Elongated nuclei with visible nucleoli" "Large, pleomorphic nuclei with multiple nucleoli" "Small, round nuclei with inconspicuous nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/447.jpg" -"448" "What is the morphology of the nuclei in the epithelial cells present in this tissue section?" "The nuclei are elongated and densely stained." "The nuclei are predominantly round and centrally located." "The nuclei are large with prominent nucleoli." "The nuclei are vesicular with clear nuclear membranes." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/448.jpg" -"449" "What feature of the tissue is indicated by the unstained material within the tissue sample?" "Accumulation of secretory product within glandular lumens." "Dense areas of collagen and fibrous tissue." "Presence of extracellular matrix or intercellular substances." "Aggregation of inflammatory cells." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/449.jpg" -"450" "Considering the tissue architecture and the absence of certain features, what aspect of the disease process does the image NOT suggest?" "Active infection" "Chronic stage of disease" "Replacement of normal loose connective tissue" "Presence of an inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/450.jpg" -"451" "Based on the structural features observed, what type of cells do the structures indicated by the black arrow most likely represent?" "Endothelial cells" "Ganglion cells" "Fibroblasts" "Epithelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/451.jpg" -"452" "What do the areas pointed to by the white arrow in the image suggest, based on their morphological appearance?" "Erythrocyte aggregation" "Dystrophic calcification" "Lymphocytic infiltration" "Hyaline degeneration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/452.jpg" -"453" "Based on the visible cellular morphology and tissue architecture, which statement is most consistent with the features of this tissue section?" "The presence of irregularly shaped, lighter pink areas indicate high-grade dysplasia." "A high cell density with atypical nuclear features suggestive of malignancy." "Well-differentiated tissue with no atypical characteristics or signs of malignancy visible." "A lack of distinct morphologic features and poor differentiation." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/453.jpg" -"454" "What is the morphology of the intranuclear inclusion bodies visible in the colonic stromal cells?" "Small, basophilic, and centrally located" "Small, basophilic, and peripherally located" "Large, eosinophilic, and marginating the nucleus" "Large, eosinophilic, and centrally located" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/454.jpg" -"455" "Analyzing the clusters of cells in the image, which feature is indicative of the type of cells present?" "The clusters containing large, polyploid nuclei." "The dark red staining highlighting outlines and internal components of the clusters." "The presence of extensive extracellular matrix within the clusters." "The absence of any staining within the central area of the cell clusters." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/455.jpg" -"456" "What is the appearance of the cytoplasm in the cells within this histological section?" "Basophilic" "Clear" "Amphophilic" "Eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/456.jpg" -"457" "What is the predominant type of cell in the background of the tissue section?" "Fibroblasts" "Adipocytes" "Epithelial cells" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/457.jpg" -"458" "How would you describe the condition of the villi based on the given histological image?" "Atrophic with shortened and distorted structures" "Preserved morphology without signs of atrophy" "Hyperplastic with elongated structures" "Completely absent, suggesting severe mucosal damage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/458.jpg" -"459" "What does the presence of brown staining in some of the epithelial cells most likely indicate?" "Accumulation of glycogen within the cells" "Necrosis of epithelial cells" "Increased production of mucus by goblet cells" "Immunoreactivity for a specific marker like CD3" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/459.jpg" -"460" "Based on the arrangement of the cells in the provided microscopic image, which description is most accurate?" "The cells are arranged in a random, disorganized manner." "The cells are arranged in interlacing fascicles or bundles." "The cells are arranged in solid nests or islands." "The cells are forming gland-like structures." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/460.jpg" -"461" "Considering the chromatin pattern within the nuclei of the cells shown in the image, which statement is most consistent with your observations?" "There are numerous and prominent nucleoli." "There are frequent mitotic figures visible." "The nuclei appear elongated and uniform." "There is a high degree of nuclear pleomorphism." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/461.jpg" -"462" "Judging by the staining characteristics of the extracellular matrix between the cells, what is the most likely composition of the matrix?" "Fibrin deposition." "Hyaline material." "Abundant mucoid material." "Dense collagenous tissue." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/462.jpg" -"463" "Based on the staining characteristics in the image, which type of cells is indicated by the presence of brown pigmentation in their cytoplasm?" "Cells abundant in glycogen content" "Cells rich in rough endoplasmic reticulum" "Cells with positive reaction for PRRSV nucleic acids" "Cells undergoing apoptosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/463.jpg" -"464" "Based on the architecture of the vessel indicated by the arrow, what is the most likely histopathological finding?" "Vessel with thickened wall and narrowed lumen" "Obliterated vessel with no discernible lumen" "Well-formed vessel with a clear lumen" "Dilated vessel with a hyperplastic endothelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/464.jpg" -"465" "Analyzing the tissue morphology, what can be inferred about the host response to the presence of the structure indicated by the arrow?" "Extensive angiogenesis surrounding the parasite" "Pronounced fibrotic encapsulation of the parasite" "Minimal inflammatory response with no significant tissue destruction" "Large multinucleated giant cell formation around the parasite" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/465.jpg" -"466" "What histological feature is indicated by the black arrow in the image?" "Fibrotic organization" "Acute inflammatory infiltrate" "Hyaline membrane formation" "Type II pneumocyte hyperplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/466.jpg" -"467" "In the area highlighted by the yellow arrow, what is the most likely composition of the large eosinophilic globules?" "Proteinaceous material such as fibrin" "Erythrocytes" "Surfactant debris" "Neutrophil extracellular traps (NETs)" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/467.jpg" -"468" "What is the appearance of the intracytoplasmic structure within the neutrophil?" "Tubular and red" "Irregular and pale blue" "Curved, elongated, and dark purple" "Round and light purple" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/468.jpg" -"469" "What is the predominant cellular arrangement observed in the branching architecture of the tissue?" "Cells forming pseudopapillary structures" "Cells forming solid nests" "Cells with clear cytoplasm arranged radially" "Cells with abundant mucinous stroma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/469.jpg" -"470" "Upon microscopic examination, how are the spindle-shaped cells with elongated nuclei arranged within the extracellular matrix?" "They are arranged in a haphazard manner" "They are arranged in tight clusters" "They are arranged in a whorled pattern" "They are arranged in a well-organized palisading pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/470.jpg" -"471" "In the histological image presented, what is the most likely composition of the dense cellular infiltrate within the connective tissue stroma?" "Predominantly lymphocytes" "Predominantly neutrophils" "Predominantly eosinophils" "Predominantly macrophages" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/471.jpg" -"472" "What is the predominant cell type observed in the dermis, based on the morphology and nuclear staining?" "Fibroblasts" "Lymphocytes" "Erythrocytes" "Macrophages" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/472.jpg" -"473" "What renal tissue component is most prevalent in the interstitial space surrounding the obsolescent glomerulus?" "Dense fibrous connective tissue" "Tubules with brush border" "Renal interstitial cells" "Adipocyte infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/473.jpg" -"474" "What type of tissue abnormality is primarily observed in the histological section?" "Normal hyaline cartilage" "Osteoarthritic cartilage" "Ossified cartilage indicating bone formation" "Cartilaginous tumor" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/474.jpg" -"475" "How would you describe the distribution of chondrocytes within the extracellular matrix?" "Evenly distributed with typical lacunae" "Isolated without any apparent organization" "Regularly spaced with smooth boundaries" "Clumped together in an atypical organization" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/475.jpg" -"476" "What is the morphology of the large cells with prominent nuclei observed in this smear?" "Round nuclei with condensed chromatin" "Bi-lobed nuclei with coarse chromatin" "Irregularly shaped nuclei with dispersed chromatin" "Oval nuclei with hyperchromatic chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/476.jpg" -"477" "What type of granules can be observed in the cytoplasm of some of the large cells?" "Eosinophilic granules" "Neutrophilic granules" "Basophilic granules" "Azurophilic granules" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/477.jpg" -"478" "What is the predominant staining characteristic of the star-shaped structure at the center of the image?" "Mixed hematoxylin and eosin staining with neither predominant" "Predominantly hematoxylin staining" "No staining, structure is clear" "Predominantly eosin staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/478.jpg" -"479" "Which of the following features in the image is NOT clearly visible but is commonly associated with the suspected diagnosis?" "Asthma-associated crystals" "Caseous necrosis" "Multinucleated giant cells" "Necrotizing granulomas" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/479.jpg" -"480" "What cellular feature suggests active transcription or replication processes within these cells?" "Scant cytoplasm" "Confluent cell arrangement" "Chromatin stippling in the nuclei" "High nucleus-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/480.jpg" -"481" "In the context of the features seen in this image, what does the darker staining of certain cells most likely indicate?" "Eosinophilic cytoplasmic staining" "Increased cytoplasmic volume" "Melanin deposition" "Dense nuclei due to hematoxylin staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/481.jpg" -"482" "What does the homogenous pink band in the subepithelial region of the tissue signify?" "Artifact of tissue processing" "Expansion of the vascular compartment" "Normal muscularis mucosa" "Thickened collagen table" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/482.jpg" -"483" "Based on the staining characteristics, what type of staining method was most likely used for this section of the hippocampus?" "Hematoxylin and eosin (H&E)" "Nissl staining" "Periodic acid-Schiff (PAS)" "Silver staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/483.jpg" -"484" "Without prior knowledge of the hippocampus, what can be deduced about the cellular density in the dentate outer layer (DOL) and the dentate molecular layer (DML) compared to the granular layer (GL)?" "The DOL and DML have a lower cellular density" "The DOL and DML have similar cellular density as the GL" "The cellular density is inconsistent in all layers" "The DOL and DML have a higher cellular density" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/484.jpg" -"485" "Based on the histologic features, what is the likely nature of the cells under the black arrow?" "Metaplastic columnar epithelial cells" "Dysplastic basal cells" "Neoplastic squamous epithelial cells" "Normal stratified squamous epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/485.jpg" -"486" "Which feature most accurately describes the transition between the neoplastic tissue indicated by the blue arrow and the non-neoplastic tissue under the black arrow?" "Clear demarcation with invasion into underlying tissue" "Gradual transition without clear borders" "Complete separation with a fibrous capsule" "Diffuse spreading with lymphocyte infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/486.jpg" -"487" "What morphological characteristic do the majority of fungal elements in this tissue sample exhibit?" "Long filamentous hyphae" "Irregular branching structures" "Budding yeast forms" "Predominantly oval or round bodies" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/487.jpg" -"488" "Identify the tissue change highlighted by the black arrow in the image." "Accumulation of mucus" "Hyperkeratosis of the epithelium" "Erosion of the overlying mucosa" "Formation of a new blood vessel" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/488.jpg" -"489" "What does the overall architecture of the tissue in the image primarily suggest?" "Inflammatory changes" "Neoplastic transformation" "Normal tissue homeostasis" "Regenerative proliferation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/489.jpg" -"490" "What feature best describes the nuclei present in the majority of cells observed in the image?" "Monomorphic nuclei with coarse chromatin" "Small, hyperchromatic nuclei with high nucleus-to-cytoplasm ratio" "Nuclear pleomorphism with varied nuclear sizes and shapes" "Uniform nuclear size and shape" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/490.jpg" -"491" "Based on the architecture and cellular activity, what is the most likely observation about the tissue in the image?" "Focal areas of calcification within the tissue" "Regular stratification with keratin layer formation" "Dense cellular infiltrate without clear organization" "Adipose tissue with characteristic vacuolated cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/491.jpg" -"492" "Based on the nuclear characteristics observed in the cells, what is the likely nature of the cell proliferation?" "Small nuclei with high cytoplasmic to nuclear ratio" "Hyperchromatic nuclei with clumped chromatin" "Prominent nucleoli within the nuclei" "Uniform nuclei with even chromatin distribution" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/492.jpg" -"493" "What does the arrangement of the cells in the tissue suggest?" "Cells embedded in abundant extracellular matrix" "Disorganized, loosely arranged cells without clear boundaries" "Well-organized epithelial structure" "Tight clusters of cells with glandular organization" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/493.jpg" -"494" "What does the arrangement of nuclei within the multi-nucleated giant cells suggest?" "Nuclei aligned along the periphery of the cell" "Nuclei forming a Langhans-type arrangement" "Nuclei arranged in a palisading pattern" "Nuclei arranged haphazardly or forming a loose cluster" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/494.jpg" -"495" "In the examined tissue sample, some cells exhibit cytoplasmic staining. What is the predominant coloration of the stained cytoplasm?" "Bright red" "Dark brown" "Intense blue" "Light pink" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/495.jpg" -"496" "In which image do the cells exhibit a high level of uniform antigen expression as indicated by the diffuse cytoplasmic positivity?" "Image C" "Image D" "Image B" "Image A" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/496.jpg" -"497" "What does the cytoplasmic appearance of these cells suggest?" "The cytoplasm contains minimal granules" "The cytoplasm has a basophilic staining quality" "The cells are larger than typical mature cells" "The cells are smaller than typical mature cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/497.jpg" -"498" "Considering the density of the cells within the microscopic field of view, what does this signify about the tissue's condition?" "Normal cellular density" "Hyperplastic process" "Atrophic process" "Sparse cellular arrangement" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/498.jpg" -"499" "When observing the dermoepidermal junction in the provided image, what is the nature of melanocytic cell arrangement?" "Regularly spaced with well-defined borders" "Scattered distribution without forming any nests" "Asymmetrical and irregularly sized nests" "Uniformly distributed with symmetrical nests" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/499.jpg" -"500" "Assessing the density and organization of the melanocytic cells within the dermis, which of the following statements best describes the observation?" "Melanocytic cells showing a dense, invasive growth pattern" "Melanocytic cells exhibiting a cohesive and structured arrangement" "Melanocytic cells with uniform pigmentation and size" "Melanocytic cells with sparse distribution and regular shape" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/500.jpg" -"501" "What is the arrangement of the bacteria observed in the image?" "Short chains or pairs" "Single rods" "Spirochetes" "Cocci in clusters" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/501.jpg" -"502" "Which histological staining characteristic helps to differentiate between nuclei and cytoplasm in this image?" "Eosinophilic staining of clear cells" "Blue to purple coloring in the nuclei" "Purple to pink coloring in the nuclei" "Uniform staining across all cellular components" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/502.jpg" -"503" "Based on the cellular density and organization, what can be inferred about the cells' differentiation status?" "Poorly differentiated with high mitotic activity" "Well-differentiated with high fibrotic activity" "Well-differentiated with low mitotic activity" "Hyperplastic with controlled proliferation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/503.jpg" -"504" "Based on the eosinophilic material present within some duct lumina, which pathological condition can be suspected?" "Necrosis" "Acute inflammation" "Proteinaceous secretions" "Amyloid deposition" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/504.jpg" -"505" "Based on the histopathological features, what is the most likely consistency of the background stroma?" "Neutrophilic" "Eosinophilic" "Basophilic" "Amphophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/505.jpg" -"506" "What is the staining characteristic of the cytoplasm in the observed cells?" "Basophilic" "Neutrophilic" "Amphophilic" "Eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/506.jpg" -"507" "What type of intracytoplasmic inclusions can be identified in this image?" "Lipid droplets" "Mallory bodies" "Polyglucosan bodies" "Russell bodies" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/507.jpg" -"508" "In the context of nuclear characteristics, which finding is most prevalent in this image?" "Hyperchromatic nuclei" "Macronucleoli" "Equivocal chromatin" "Vesicular nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/508.jpg" -"509" "What is the predominant cell type in this microscopic image based on the nuclear morphology?" "Neutrophils" "Lymphocytes" "Monocytes" "Eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/509.jpg" -"510" "Based on the cytoplasmic characteristics of the cells, what type of staining technique has likely been used?" "Pap stain" "Gram stain" "Wright's stain" "Acid-fast stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/510.jpg" -"511" "What cellular morphology feature is predominantly observed in the cells within the nests?" "Spindle-shaped cells with hyperchromatic nuclei" "Polygonal cells with amphophilic cytoplasm and prominent nucleoli" "Small round cells with high nuclear-to-cytoplasmic ratio" "Cuboidal cells with clear cytoplasm and inconspicuous nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/511.jpg" -"512" "What characterizes the stroma seen in the tissue section?" "It contains large areas of collagen deposition without blood vessels" "It displays extensive calcification within the stromal tissue" "It consists of thin strands with abundant red-staining blood vessels" "It shows predominantly adipose tissue between the cell nests" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/512.jpg" -"513" "Based on the image, how would you describe the condition of the cell nuclei?" "The nuclei are enlarged and hyperchromatic" "The nuclei are not stained and appear as lighter areas within the cells" "There is a loss of nuclear detail due to intense staining" "The nuclei show positive brown staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/513.jpg" -"514" "What does the overall architecture of the tissue, including the structural features not labeled 'A', suggest about the origin of this tissue sample?" "Cortex of the brain" "Squamous epithelium" "Cardiac muscle" "Intestinal mucosa" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/514.jpg" -"515" "Given the histopathological features observed, which of the following changes in the surrounding tissue can be inferred?" "An increase in collagen or smooth muscle fiber presence." "Degeneration of surrounding connective tissue." "Increased vascularization and angiogenesis." "Reduction in collagen or smooth muscle fiber presence." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/515.jpg" -"516" "What type of matrix is most likely represented by the lighter-staining area within the specimen?" "Dense irregular connective tissue" "Chondroid matrix" "Adipose tissue" "Myxoid matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/516.jpg" -"517" "What does the presence of well-organized tubular structures surrounded by clear cells indicate?" "Glandular epithelium" "Squamous cell carcinoma" "Tubular adenoma" "Ductal carcinoma in situ" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/517.jpg" -"518" "Observing the lamina propria marked with a thick arrow, which of the following conditions would you infer from its appearance?" "Suggestive of increased fibrosis" "Compatible with normal tissue structure" "Evidence of acute inflammation" "Indicative of lymphoid hyperplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/518.jpg" -"519" "Based on the area indicated by the carets at the bottom of the image, what can be most accurately deduced?" "Presence of granulomatous inflammation" "Signs of tissue regeneration" "Indication of hemorrhage" "Evidence of crypt abscess formation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/519.jpg" -"520" "Based on the spindle-shaped morphology of cells in the lower region of the image, which type of tissue is likely represented here?" "Connective tissue" "Nervous tissue" "Skeletal muscle" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/520.jpg" -"521" "What does the presence of the brown staining in the lower region of the image infer about the tissue?" "Indication of melanin accumulation" "Presence of hemosiderin" "Result of immunohistochemical staining for a specific protein" "Accumulation of lipofuscin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/521.jpg" -"522" "What is the predominant feature observed in the provided image of heart tissue?" "Replacement of cardiomyocytes with adipose tissue" "Abundant deposition of connective tissue indicative of fibrosis" "Extensive area of calcification" "Normal distribution of cardiomyocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/522.jpg" -"523" "What is the predominant cell type present in this high-power field image of a hematopoietic tissue?" "Erythroblasts with prominent nucleoli" "Small lymphocytes with scant cytoplasm" "Neutrophils with segmented nuclei" "Cells with eccentrically placed nuclei and basophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/523.jpg" -"524" "The presence of a perinuclear hof, as observed in this image, indicates a specific cellular feature. What does this feature represent?" "Aggregation of melanin pigment around the nucleus" "Zone of clearing around the nucleus due to the Golgi apparatus" "Accumulation of lipid droplets within the cytoplasm" "Area of RNA synthesis and ribosomal biogenesis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/524.jpg" -"525" "Which feature of the image suggests that the tissue is an abnormal proliferation or infiltration rather than normal hematopoietic tissue?" "Presence of megakaryocytes or other hematopoietic precursors" "High nuclear-to-cytoplasmic ratio of the cells" "Relative paucity of adipose tissue and stromal cells" "Predominance of cells with eccentrically placed nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/525.jpg" -"526" "What feature distinguishes the large cells observed in the center of this histological image?" "Multiple nuclei arranged in a horseshoe pattern" "A single eccentric nucleus" "A single large central nucleus" "Multiple nuclei randomly dispersed throughout the cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/526.jpg" -"527" "Based on the density and color of the inclusions within the cytoplasm of some large cells, what is the most likely identity of these inclusions?" "Phagocytosed red blood cells or precursors" "Cytoplasmic glycogen deposits" "Lipid droplets" "Hemosiderin granules" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/527.jpg" -"528" "Regarding the overall cellularity of the bone marrow sample depicted in the image, which description is the most accurate?" "Hypercellular with increased blasts" "Dysplastic with bizarre cellular morphology" "Aplastic with markedly decreased cellularity" "Normocellular with adequate maturation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/528.jpg" -"529" "What does the surrounding matrix and distribution of cells in this tissue sample suggest about the potential underlying condition?" "Normal healthy tissue" "Acute inflammatory reaction" "Neoplastic growth" "Chronic inflammatory process" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/529.jpg" -"530" "Assessing the immunohistochemical staining pattern, where is the strongest staining intensity predominantly observed?" "Within the nucleus" "Throughout the cytoplasm" "Around the periphery of the cells" "Evenly distributed across the entire cell" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/530.jpg" -"531" "What feature distinguishes the cells within the area marked by a circle?" "A single central nucleus with an extensive envelope of cytoplasm" "A large, singular lipid vacuole dominating the cytoplasm" "Multiple small lipid droplets distributed throughout the cytoplasm" "A large eccentric nucleus surrounded by a thin rim of cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/531.jpg" -"532" "What is the primary characteristic of the cells marked with a square?" "Presence of lipofuscin indicating senescent cells" "Smaller and more numerous vacuoles with dense cytoplasm" "Nuclei located centrally within a homogeneous cytoplasm" "A hyperchromatic nucleus due to high cell turnover" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/532.jpg" -"533" "Which feature seen among the densely packed cells in the right and lower left areas of the image typically indicates reactive or benign lymphocytes rather than malignant ones?" "Prominent cytoplasm" "An irregular contour of the nucleus" "Uniform dark staining of nuclei" "Variation in cell shape" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/533.jpg" -"534" "What type of cellular growth pattern does the tissue most predominantly display?" "Complex papillary structures" "Trabecular arrangement" "Solid nesting pattern" "Acinar formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/534.jpg" -"535" "Based on the histopathological features observed in the image, what type of tissue reaction pattern can be inferred?" "Lichenoid" "Psoriasiform hyperplasia" "Spongiosis" "Granulomatous" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/535.jpg" -"536" "In the image provided, what cytoplasmic characteristic do the glial cells mainly exhibit?" "Cytoplasm is basophilic with numerous granules" "Cytoplasm appears vacuolated and clear" "Cytoplasm is abundant with prominent nucleoli" "Cytoplasm stains strongly eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/536.jpg" -"537" "Considering the characteristic stains in the image, which highlighted area would be most likely to be positive for CD31/PAS, indicating endothelial cells?" "The solid pink areas without any cell-like structures" "Areas solely with darkly stained nuclei" "The heterogeneously stained structure in the top right corner" "Areas with homogeneously stained cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/537.jpg" -"538" "Upon examination of the tissue's stroma, which characteristic is most evident?" "The stroma is predominantly composed of adipose tissue" "The stroma contains some small capillaries and is mildly eosinophilic" "There is extensive angiogenesis with numerous large blood vessels" "The stroma appears highly fibrotic with dense collagen deposits" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/538.jpg" -"539" "Based on the microscopic image, what type of tissue is predominantly surrounding the granulomas?" "Adipose tissue" "Skeletal muscle tissue" "Dense connective tissue" "Hyaline cartilage" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/539.jpg" -"540" "What immune cells are likely represented by the scattered mononuclear cells throughout the image?" "Histiocytes" "Neutrophils" "Eosinophils" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/540.jpg" -"541" "What type of inflammatory cells predominate in the dermis as viewed in this H&E stained skin section?" "Neutrophils" "Lymphocytes" "Eosinophils" "Macrophages" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/541.jpg" -"542" "How would you describe the spacing between the collagen fibers in the dermis based on this image?" "Highly condensed" "Normal compactness" "Increased with separation" "Unidentifiable due to over-staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/542.jpg" -"543" "What additional feature suggests inflammation in this histological image of skin?" "Edema" "Necrotic tissue" "Hyperkeratosis" "Granuloma formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/543.jpg" -"544" "In the stratified squamous epithelium presented, what cellular feature is most prominent in the basal layer?" "Atypical cells with variations in size, shape, and staining intensity" "Uniformity in cellular size and shape" "Presence of keratinization in the basal cells" "Decreased nuclear-to-cytoplasmic ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/544.jpg" -"545" "Which finding is consistent with severe acute glomerular injury in this image?" "Even distribution of capillary loops" "Double-contouring of basement membranes" "Adhesions towards Bowman's capsule" "Well-defined capillary lumina" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/545.jpg" -"546" "In the examined tissue, what is the implication of the presence of large, multinucleated cells with abundant eosinophilic cytoplasm?" "Suggestive of syncytiotrophoblastic cells in a tumor context" "A typical finding in benign epithelial tissue" "A sign of highly specialized and functional normal tissue" "An indication of robust inflammatory response" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/546.jpg" -"547" "What observation can be made regarding the cellular architecture in this microscopic image?" "Homogeneous population of spindle-shaped cells" "Homogenous population of polygonal cells" "Homogenous population of round cells" "Heterogeneous population of spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/547.jpg" -"548" "What is the cellular morphology that predominates in the image?" "Basophilic cytoplasm with round nuclei" "Eosinophilic cytoplasm with elongated nuclei" "Amphophilic cytoplasm with lobulated nuclei" "Clear cytoplasm with hyperchromatic nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/548.jpg" -"549" "What characteristic feature of plasma cells is visible in the histological image?" "A spindle-shaped morphology" "Centrally located nucleus within the cell" "Multiple nuclei within the cell cytoplasm" "An eccentric nucleus and abundant cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/549.jpg" -"550" "How would you describe the histologic pattern of inflammatory cell infiltration in this image?" "Focal aggregates surrounded by normal tissue" "Predominantly perivascular infiltration" "Diffuse homogeneous infiltration" "Lymphoplasmacytic infiltration in a patchy distribution" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/550.jpg" -"551" "Considering the condition of the stratum corneum in this histological image, how can its appearance be best described?" "Thickened with extensive scaling" "Hyperkeratosis with parakeratosis" "Irregular acanthosis" "Intact with no obvious signs of breach or erosion" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/551.jpg" -"552" "What microscopic feature is indicated by the arrows in the stratum corneum?" "Neutrophilic infiltration" "Hyperkeratosis" "Spongiform pustules" "Melanocytic proliferation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/552.jpg" -"553" "Which description best fits the appearance of the epidermal layer?" "Thin epidermis with flattening of the rete ridges" "Thickened epidermis with elongation of the rete ridges" "Normal epidermis with regular rete ridges" "Atrophic epidermis with loss of rete ridges" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/553.jpg" -"554" "In the dermal layer, what cellular infiltration is observed around the dilated superficial blood vessels?" "Eosinophils and mast cells" "Lymphocytes and plasma cells" "Macrophages and fibroblasts" "Lymphocytes and neutrophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/554.jpg" -"555" "Based on the features of the peritubular capillaries (PTCs) identified in the image, which statement accurately describes their histologic characteristics?" "The PTCs demonstrate significant luminal narrowing" "The PTCs are not associated with the tubules" "The PTCs are surrounded by inflammatory cells" "The PTCs have thickened vessel walls" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/555.jpg" -"556" "Based on the nuclear characteristics observed in the cells, which of the following best describes the nuclear chromatin pattern?" "Dense and hyperchromatic" "Mildly coarse" "Vesicular with prominent nucleoli" "Uniformly distributed fine granular" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/556.jpg" -"557" "What can be inferred about the nucleus-to-cytoplasm ratio in these cells?" "Nucleus almost occupies the entire cell volume" "High nucleus-to-cytoplasm ratio" "Nucleus is small and insignificant compared to the cytoplasm" "Low nucleus-to-cytoplasm ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/557.jpg" -"558" "What can be inferred about the nature of the tissue based on the cellular morphology observed?" "Adipose tissue origin" "Epithelial tissue origin" "Neural tissue origin" "Mesenchymal tissue origin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/558.jpg" -"559" "Based on the histological features observed, what is the most likely type of epithelium present at the surface layer?" "Simple squamous epithelium" "Transitional epithelium" "Pseudostratified ciliated columnar epithelium" "Stratified squamous keratinized epithelium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/559.jpg" -"560" "What is the predominant cell type based on the morphology observed in this tissue section?" "Adipocytes" "Columnar epithelial cells" "Squamous epithelial cells" "Spindle-shaped mesenchymal cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/560.jpg" -"561" "What feature is indicated by the yellow arrows in the renal tissue image?" "Glomerular hypercellularity" "Inflammatory cell infiltration" "Normal renal parenchyma" "Interstitial fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/561.jpg" -"562" "Based on the cellular morphology, which component seems to dominate the cytoplasmic content of the cells viewed under the microscope?" "Scant eosinophilic material" "Abundant lipid droplets" "Extensive rough endoplasmic reticulum" "Numerous mitochondria" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/562.jpg" -"563" "What does the presence of distinct intranuclear inclusions within some of the cells suggest?" "Hallmark of degenerative changes in benign tissues" "Typical findings of a viral infection" "Indicative of high-grade malignant neoplasm" "Diagnostic of specific nutrient deficiencies" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/563.jpg" -"564" "What is the characteristic feature of the giant cells observed in the image?" "Multiple, bland nuclei with no significant pleomorphism" "Single, hyperchromatic nucleus with irregular borders" "Multiple nuclei with hyperchromasia and significant pleomorphism" "Single, centrally located nucleus with abundant eosinophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/564.jpg" -"565" "Based on the coloration seen in the image, what type of staining technique is most likely to have been used?" "Hematoxylin and eosin (H&E) stain" "Periodic acid–Schiff (PAS) stain" "Masson's trichrome stain" "Wright-Giemsa stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/565.jpg" -"566" "What is the predominant cell type observed in the microscopic image?" "Neutrophils" "Lymphocytes" "Epithelial cells" "Eosinophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/566.jpg" -"567" "Identify the anucleate structures present among the cells in this hematological specimen." "Erythrocytes" "Megakaryocytes" "Basophils" "Platelets" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/567.jpg" -"568" "Which of the following features is NOT correctly identified in the larger cells found among the mostly homogeneous smaller cells?" "Larger cells resembling hematopoietic lineage" "Larger cells with highly prominent nucleoli" "Larger cells with bi-lobed nuclei" "Larger cells with more abundant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/568.jpg" -"569" "Considering the nuclei of the cells in this image, which of the following observations is correct?" "There is an apparent complete absence of nuclei in the epithelial cells." "The nuclei show significant pleomorphism and hyperchromasia." "The nuclei are uniformly shaped and are basally located." "The nuclei are located apically within the cells." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/569.jpg" -"570" "What does the staining intensity of the cytoplasm of the cells in this tissue section suggest?" "The irregular, intense staining of some individual cells indicates the presence of a widespread infection." "A consistent, dark staining pattern throughout the cytoplasm indicates high levels of cytoplasmic inclusions or granules." "The intense staining of all cells suggests a uniform expression of cellular proteins throughout the tissue." "The light staining of the cytoplasm suggests that the staining technique may be targeting specific proteins or cell structures." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/570.jpg" -"571" "What is the predominant staining characteristic of the elongated fibers in the extracellular matrix of this tissue?" "Pink to red" "Blue to purple" "Green to yellow" "Black or very dark brown" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/571.jpg" -"572" "In evaluating the tissue's architecture, what is the general shape of the spaces likely representative of vascular structures or ducts?" "Perfectly Tubular" "Irregularly shaped" "Round or oval" "Rhomboidal" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/572.jpg" -"573" "What is the predominant cellular arrangement observed in this tissue sample?" "Storiform pattern" "Pseudorosette formation" "Haphazard arrangement" "Fascicular pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/573.jpg" -"574" "What is the characteristic of the background material in the image?" "Hyaline and smooth" "Fibrous and acellular" "Granular and eosinophilic" "Homogeneous and basophilic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/574.jpg" -"575" "Based on the image, how would you describe the chromatin pattern within the nuclei of the cells?" "Chromatin is showing peripheral margination along the nuclear membrane." "It is evenly distributed and finely granular throughout the nuclei." "Chromatin shows a hyperchromatic pattern with some cells exhibiting distinct nucleoli." "The chromatin pattern is homogeneously distributed and smudged." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/575.jpg" -"576" "What is the nature of the stroma in the image?" "Eosinophilic" "Hyalinized" "Edematous" "Myxoid" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/576.jpg" -"577" "On examination of the nuclei within the cells, how would they best be described?" "Hyperchromatic and uniform" "Vesicular and binucleated" "Hypochromatic and pleomorphic" "Clear and anaplastic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/577.jpg" -"578" "What is the predominant pattern of the cell organization in the presented histological image?" "Fasicular pattern" "Alveolar pattern" "Herringbone pattern" "Nodular pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/578.jpg" -"579" "What histological evidence suggests inflammatory infiltration within the tissue?" "Homogeneously sized nuclei with uniform contours" "Hyperchromatic nuclei with irregular shapes" "Light staining suggestive of edema" "Small cells with dark nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/579.jpg" -"580" "Observing the variations in cellular density within the image, which process is likely indicated by the higher density of nuclei in certain areas?" "Ischemic tissue damage" "Dysplastic cellular growth" "High mitotic activity" "Inflammatory cell infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/580.jpg" -"581" "Based on the pathological changes visible, what does the dilation of the tubules (indicated by stars) primarily suggest?" "Tubular atrophy" "Obstruction of lower urinary tract" "Acute tubular necrosis" "Nephrocalcinosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/581.jpg" -"582" "What type of steatosis is predominantly observed in the liver tissue section?" "No steatosis present" "Microvesicular steatosis" "Macrovesicular steatosis" "Both microvesicular and macrovesicular steatosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/582.jpg" -"583" "What is the predominant color of the intratubular casts within the lumens of the tubules in the image?" "Green" "Dark red" "Blue" "Pink" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/583.jpg" -"584" "What additional feature is seen within the peritubular capillaries in the image?" "Red blood cells" "Neutrophils" "Foam cells" "Giant cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/584.jpg" -"585" "Based on the morphology of the cells in the image, what cellular feature is predominantly visible?" "Pleomorphism" "Homogenous nuclear size" "Isomorphic cell shapes" "Abundant cytoplasm in most cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/585.jpg" -"586" "By examining the blood vessels in the dermis, which of the following pathological features can be identified?" "Dilated and congested blood vessels suggesting extravasation" "Evidence of angiogenesis with immature vessel formation" "Arteriosclerosis with thickened blood vessel walls" "Presence of well-formed granulomas around the vessels" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/586.jpg" -"587" "What does the clear space surrounding some blood vessels in the dermis most likely represent?" "Focal areas of fibrosis" "Presence of edema fluid" "Accumulation of mucin" "Infiltration of inflammatory cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/587.jpg" -"588" "Assessing the stromal component and extracellular matrix in this tissue section, what is a notable feature?" "The stromal component is heavily calcified throughout the tissue section" "There is a conspicuous inflammatory infiltrate within the stroma" "The extracellular matrix stains darker than the cellular components" "The extracellular matrix stains lighter, particularly around the blood vessels" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/588.jpg" -"589" "What can be inferred about the staining properties of the cytoplasm in these cells?" "The cytoplasm shows weak and patchy staining" "The cytoplasm is not reactive to the immunohistochemical stain" "The cytoplasm exhibits a strong and uniform staining pattern" "The cytoplasm displays variable staining intensity with no specific pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/589.jpg" -"590" "Considering the nuclear detail in this image, which of the following statements is most accurate?" "Nuclei are not easily discernible due to strong cytoplasmic staining" "Nuclear pleomorphism is a prominent feature" "Nuclei are hyperchromatic with irregular shapes" "Nuclei exhibit prominent nucleoli in most cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/590.jpg" -"591" "Based on the arrangement and morphology of the cells, which description most accurately portrays the tissue's architecture?" "The cells are arranged in sheets or clusters with no obvious atypia" "The cells display significant pleomorphism and atypical features" "The cells form glandular structures with luminal spaces" "The cells are loosely arranged without a discernible pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/591.jpg" -"592" "Observing the cellular clusters within the image, what pattern do they primarily display?" "Clusters arranged in a branching or papillary pattern" "Large syncytial aggregates with minimal separation" "Isolated single cells without organization" "Solid nests without any architectural complexity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/592.jpg" -"593" "The stroma visible in the image is characterized by which of the following features?" "Heavily infiltrated with inflammatory cells" "Dense and collagenous with numerous fibroblasts" "Prominent myxoid changes with stellate cells" "Lightly stained with occasional eosinophilic areas" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/593.jpg" -"594" "What cellular feature indicates the presence of yeasts in this microscopic image?" "Small cells with multi-lobed nuclei" "Small cells with dense, central nuclei" "Large cells with kidney-shaped nuclei" "Refractile, round structures within large cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/594.jpg" -"595" "In the top right panel of the image, what feature is observable within the cytoplasm of one cell?" "Psammoma bodies" "Hyaline cytoplasmic inclusion" "Lipofuscin granules" "Mitotic figures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/595.jpg" -"596" "What characteristic pattern can be observed in the tissue section in the bottom right panel of the image?" "Papillary pattern" "Nesting growth pattern" "Alveolar growth pattern" "Solid growth pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/596.jpg" -"597" "What is the staining characteristic of the glandular cells’ cytoplasm viewed in this histological image?" "Basophilia" "Neutrophilia" "Hematoxylinophilia" "Acidophilia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/597.jpg" -"598" "Identify the type of giant cells present in this tissue section based on their morphological characteristics." "Langhans giant cells" "Osteoclast-like giant cells" "Touton giant cells" "Foreign body giant cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/598.jpg" -"599" "What feature in the image suggests the presence of a localized immune response?" "Large cells with pale cytoplasm within the epithelium" "Multilayered appearance of the epithelium" "Clusters of pigmented cells around the pilosebaceous unit" "Darkly-stained small nuclei in the surrounding connective tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/599.jpg" -"600" "Based on the microscopic view, what might the presence of brown or black granules within some cells' cytoplasm indicate?" "Cytoplasmic inclusions of a viral infection" "Accumulation of lipofuscin due to cellular aging" "Melanin produced by melanocytes or related processes" "Presence of hemosiderin due to hemorrhage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/600.jpg" -"601" "How would you categorize the arrangement of the spindle cells observed in the eosinophilic stroma?" "Arranged in well-defined, uniform fascicles" "Randomly distributed without a distinct pattern" "Organized in tight clusters" "Arranged in loose fascicles or streams" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/601.jpg" -"602" "What can be inferred about the mitotic activity in this tissue sample?" "It suggests moderate mitotic activity with occasional mitotic figures" "It indicates low mitotic activity with rare mitotic figures" "Mitotic figures are absent, indicating no mitotic activity" "It reflects high mitotic activity with numerous mitotic figures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/602.jpg" -"603" "Based on the uniform basal line of nuclei, what type of epithelium is present in this image?" "Transitional epithelium" "Squamous epithelium" "Cuboidal epithelium" "Columnar epithelium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/603.jpg" -"604" "What is the most notable feature of the renal glomerulus in this image?" "Significant atrophy of the glomerular tuft" "Presence of numerous inflammatory cells within the glomerulus" "Increase in cellularity within the glomerular tufts" "Clear delineation of glomerular basement membranes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/604.jpg" -"605" "Based on the pathology demonstrated in the glomerulus, what condition might this image suggest?" "Minimal change disease with effacement of foot processes" "Membranoproliferative glomerulonephritis with tram-track appearance" "Diabetic nephropathy with typical Kimmelstiel-Wilson nodules" "Acute tubular necrosis with prominent tubular damage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/605.jpg" -"606" "What does the circled area in the renal tissue section indicate?" "Sclerotic glomerulus" "Lipid accumulation" "Inflammatory infiltrate" "Hyperplastic arteriolosclerosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/606.jpg" -"607" "Based on the PAS staining pattern, how is the carbohydrate-rich structure of the tissue altered?" "Normal brush border appearance" "Accumulation of glycogen in cells" "Enhanced glycoprotein synthesis" "Decreased basement membrane definition" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/607.jpg" -"608" "Based on the histological architecture, what possible condition does this tissue section suggest?" "Tubular adenoma" "Villous atrophy" "Hyperplastic polyps" "Goblet cell carcinoid" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/608.jpg" -"609" "What does the increased presence of dense cells with darker staining nuclei within the epithelium likely indicate?" "Hyperchromatic malignant cells" "Lipid-laden macrophages" "Inflammatory response" "Metaplastic transformation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/609.jpg" -"610" "Based on the arrangement of the spindle-shaped cells, how would you describe their organization?" "The cells are arranged in a disorganized fashion" "The cells are uniformly distributed with ample stromal support" "The cells are neatly arranged in rows" "The cells exhibit a uniform, structured pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/610.jpg" -"611" "What type of bone morphology is suggested by the image at the center of the tissue section?" "Dense bone with minimal marrow space" "Irregular bone lacking organized structure" "Compact bone with Haversian system" "Trabecular bone with lacunae containing osteocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/611.jpg" -"612" "In the tissue surrounding the bone, what is indicated by the presence of spindle-shaped fibroblasts in dense fibrous connective tissue?" "Suggestion of well-differentiated neoplastic cells" "Sign of normal healing tissue" "Evidence of chronic irritation or invasive growth" "Indication of acute inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/612.jpg" -"613" "In observing the lower third of the epithelium, what can be inferred about the cellular polarity?" "Cellular arrangement suggests growth in a single cell layer" "Cells demonstrate well-maintained polarity" "Cells lack uniform alignment and orientation" "Cells exhibit strict uniform alignment" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/613.jpg" -"614" "Based on the tissue morphology, what is the likely tissue component staining pink to red in this image?" "Necrotic debris" "Lipid-filled vacuoles" "Glycogen deposits" "Connective tissue elements" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/614.jpg" -"615" "When assessing for Glypican-3 (GPC-3) expression using immunohistochemistry in this tissue section, what staining pattern would you expect in positive cells?" "A clear cytoplasmic outline with dark staining" "A pale cytoplasmic staining and dark nucleic staining" "Homogeneous light staining throughout the cellular components" "Dark cytoplasmic staining in contrast to the background" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/615.jpg" -"616" "Based on the evaluation of cellular morphology, what characteristic is consistent with the diagnosis implied by the tissue sample?" "Ciliated pseudostratified columnar epithelium" "Well-defined cell borders and abundant cytoplasm" "Small round blue cells with high nuclear-to-cytoplasmic ratio" "Multinucleated giant cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/616.jpg" -"617" "Based on the morphological characteristics seen in the image, what is the majority cell type?" "Megakaryocytes" "Neutrophils" "Erythrocytes" "Plasmacytoid lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/617.jpg" -"618" "What does the presence of refractile material indicated by the arrowheads suggest?" "Degenerative changes in collagen fibers" "Accumulation of mucinous substance" "Presence of a foreign substance" "Normal lung tissue components" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/618.jpg" -"619" "Based on the proportion of Ki-67-positive cells observed in Panel A, which of the following best describes the proliferative activity within the tissue?" "No proliferative activity" "Moderate proliferative activity" "Low proliferative activity" "High proliferative activity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/619.jpg" -"620" "Based on the orientation of the nuclei in the peripheral columnar cells, how would you describe their polarity?" "Nuclei show no particular orientation" "Nuclei randomly dispersed without polarity" "Nuclei polarized away from the center of the cluster" "Nuclei polarized towards the center of the cluster" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/620.jpg" -"621" "Observing the tissue organization, which statement accurately describes the maturation sequence of the squamous epithelium as seen in the image?" "There are areas where the normal maturation sequence is disrupted" "The normal maturation sequence appears uninterrupted and well-structured" "There is an evident transition from basal cells to superficial squamous cells" "The squamous cells exhibit uniform maturation throughout the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/621.jpg" -"622" "In Fig. 2A, the matrix morphology is indicative of which type of tissue?" "Loose Connective Tissue" "Chondroid Matrix" "Adipose Tissue" "Dense Fibrous Connective Tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/622.jpg" -"623" "Which type of connective tissue component is visible beneath the epithelial layer?" "Elastic connective tissue" "Dense regular connective tissue" "Dense irregular connective tissue" "Loose connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/623.jpg" -"624" "In the provided PAS-stained image, how does the basement membrane of the glomerular capillaries appear?" "Stained lightly, almost transparent" "Interrupted and distorted" "Smooth and uninterrupted" "Thickened and homogeneous" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/624.jpg" -"625" "Based on the cellular morphology and staining characteristics of the mass, which histological feature is indicated by the purple-stained cells in the center of the image?" "Adipose tissue" "Neoplastic tissue" "Hyalinized stroma" "Necrotic tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/625.jpg" -"626" "Based on the cells labeled with 'n' in the interstitial space, which hormone are the cells primarily responsible for secreting?" "Follicle-stimulating hormone (FSH)" "Lutenizing hormone (LH)" "Estrogen" "Testosterone" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/626.jpg" -"627" "What does the presence of cells marked with '1' near the basement membrane indicate?" "Sertoli cell dysfunction" "Presence of Leydig cells" "Onset of inflammatory response" "Initiation of the spermatogenic cycle" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/627.jpg" -"628" "Based on the immunohistochemical staining pattern, which cellular component predominantly expresses the targeted antigen?" "Cytoplasm" "Extracellular matrix" "Nuclei" "Cell membrane" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/628.jpg" -"629" "Based on the granules observed in the hepatocytes, which staining method is most likely used?" "Periodic acid–Schiff (PAS)" "Hematoxylin and eosin (H&E)" "Prussian blue" "Masson's trichrome" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/629.jpg" -"630" "Upon examination of the micrograph, which area most likely represents the deeper part of the dermis?" "The area featuring a densely packed cellular structure" "The regions marked with asterisks showing a paucity of darkly stained fibers" "The regions with the most uniform staining" "The region with elongated, wavy structures indicated by arrows" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/630.jpg" -"631" "What is the overall staining characteristic of the cytoplasm observed in most of the cells within the image?" "Completely hyaline" "Homogenously eosinophilic" "Eosinophilic to lightly basophilic" "Uniformly basophilic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/631.jpg" -"632" "Based on the tissue morphology and staining characteristics, what is the likely nature of the densely packed cellular structures observed in the image?" "Necrotic cells with loss of cellular detail" "Anaplastic cells with high-grade pathology" "Dysplastic cells with mild atypia" "Well-differentiated cells with no evidence of pathology" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/632.jpg" -"633" "What does the presence of small cells with darkly staining nuclei and scant cytoplasm throughout the tissue suggest?" "Presence of macrophages involved in tissue repair" "Presence of endothelial cells involved in angiogenesis" "Presence of lymphocytes in a normal adaptive immune response" "Presence of neutrophils indicative of an inflammatory response" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/633.jpg" -"634" "What feature in the image suggests there may be an inflammatory process occurring within the tissue?" "Smaller cells with darker nuclei" "Large cells with abundant eosinophilic cytoplasm" "Clear, empty-looking spaces" "Fibrous, eosinophilic extracellular matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/634.jpg" -"635" "Which hematopoietic cell type is indicated by the arrow in the main image?" "Erythroblast" "Megakaryocyte" "Histiocyte" "Myelocyte" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/635.jpg" -"636" "In the main image, which of the following statements is true about the immature precursor cells observed?" "They are the smallest cells in the image" "They have brightly stained cytoplasm with distinct cell boundaries" "They have small, dense nuclei and no visible nucleoli" "They have large, round nuclei with visible nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/636.jpg" -"637" "What feature is indicated by the yellow arrows in the image?" "Blood vessels containing red blood cells" "Bands of collagenous stroma separating cell nests" "Areas of necrosis within the tissue" "Adipose tissue interspersed within the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/637.jpg" -"638" "Based on the image, what can be inferred about the cell population?" "The cells exhibit monomorphism with uniform nucleus size." "The cells resemble adipocytes with large vacuolated cytoplasm." "The cells show pleomorphism with variable shapes and sizes." "The cells are primarily lymphocytes with small, dense nuclei." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/638.jpg" -"639" "The histology in the image suggests that the tissue is:" "Exhibiting fat necrosis with typical 'soap bubble' appearance." "Displaying fibrotic changes with extensive collagen deposition." "Undergoing active inflammation with predominantly neutrophilic infiltration." "Characterized by hypercellularity suggesting proliferative activity." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/639.jpg" -"640" "What is the predominant morphological feature seen within the Bowman's capsule in this glomerulus?" "A thin lining of parietal epithelial cells" "A collapse of the glomerular tuft" "A layered, crescentic arrangement of cells" "A dilation of the Bowman's space" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/640.jpg" -"641" "What characteristic is common to the cells indicated by the white, black, and red arrows?" "They all present with a high nucleus-to-cytoplasm ratio" "They all exhibit distinct nucleoli" "They all show small, hyperchromatic nuclei" "They all have abundant eosinophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/641.jpg" -"642" "Which cell labeled in the image is characterized by a high density of cytoplasmic granules that stain deep blue-purple?" "Cell labeled number 1" "Cell labeled number 2" "Cell labeled number 4" "Cell labeled number 5" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/642.jpg" -"643" "Which cell in the image represents an immature neutrophil with a characteristic banded nuclear shape?" "Cell labeled number 1" "Cell labeled number 5" "Cell labeled number 4" "Cell labeled number 2" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/643.jpg" -"644" "Which of the following cells has a multi-lobed nucleus typical of a mature neutrophil?" "Cell labeled number 3" "Cell labeled number 1" "Cell labeled number 4" "Cell labeled number 5" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/644.jpg" -"645" "When assessing the potential for malignancy in this histological section, what feature of the nuclei is most relevant?" "Hyperchromatism" "Uniformity in size and shape" "Significant pleomorphism" "Conspicuous nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/645.jpg" -"646" "Based on the cellular morphology observed in the image, which feature does NOT suggest a benign melanocytic lesion?" "Variation in cell size and shape" "Clear cytoplasmic boundaries" "Individual cells nested within the stroma" "Even distribution of cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/646.jpg" -"647" "What can be inferred about the cellular organization visible in the image?" "The cells are scattered individually without forming distinct structures" "The cells organize into clusters reminiscent of granulomas" "The cells form a structured epithelial layer" "The cells are arranged in a loose connective tissue pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/647.jpg" -"648" "What is the likely composition of the extracellular matrix surrounding the cellular clusters?" "Hyaline cartilage with lacunae and chondrocytes" "Dense irregular connective tissue with abundant collagen fibers" "Loose connective tissue with a homogeneous extracellular matrix" "Adipose tissue with clear vacuoles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/648.jpg" -"649" "The overall tissue architecture observed in the image is indicative of what type of growth pattern?" "Organized and structured growth" "Rosette formation" "Lobular architecture" "Disorganized and anarchic growth" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/649.jpg" -"650" "What can be inferred about the nuclear characteristics of the superficial cells?" "The nuclear size is consistent across the cells" "Nucleoli are not visible within the nuclei" "The nuclei are small and uniform in size" "The nuclei are large and hyperchromatic with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/650.jpg" -"651" "Based on the nuclear morphology, what type of leukocytes are predominantly visible within the stroma?" "Monocytes" "Polymorphonuclear leukocytes" "Eosinophils" "Lymphocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/651.jpg" -"652" "When evaluating the Bowman's capsule surrounding the central glomerulus, what morphological change is apparent?" "Thicker than normal capsule appearance" "Presence of segmental sclerosis" "Uniform cellularity throughout the capsule" "Thinning of the capsule walls" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/652.jpg" -"653" "Which observation corresponds to the peripheral cellular population in the renal tissue?" "The cells are sparse and isolated with no evidence of clustering" "The cells show uniform size and staining properties" "There is a predominance of cells with eosinophilic cytoplasm" "There is a diverse population of cells with varied sizes and darker stained nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/653.jpg" -"654" "What is the appearance of the nuclei within the intravascular mass?" "The nuclei appear elongated with mild variation in size and shape without obvious atypia" "The nuclei are large with prominent nucleoli and frequent mitotic figures" "The nuclei appear small, round, and uniform with dense chromatin" "The nuclei show marked variation in size and shape with hyperchromasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/654.jpg" -"655" "What key histopathological evidence from the image supports the likelihood of neoplastic activity in the right side of the sample?" "Eosinophilic cytoplasmic inclusions in some cells" "Decreased keratinization of the superficial layers" "Increase in cytoplasmic basophilia throughout the sample" "Smooth gradation between normal and abnormal cellular architecture" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/655.jpg" -"656" "What does the presence of cells with clear cytoplasm and visible nuclei suggest about the tissue environment?" "Uniform cellular response to the stain" "Presence of diverse cell types within the tissue" "Indication of a monotypic cell population" "High degree of cellular pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/656.jpg" -"657" "Observing the left side of the image, what does the densely stained branching fibers region primarily represent?" "Neuronal processes in the molecular layer" "Glial cells proliferating in the white matter" "Myelinated axons in the white matter" "Blood vessels within the Purkinje cell layer" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/657.jpg" -"658" "Based on the histological features observed in the image, which region is most likely to contain Purkinje neurons?" "The densely stained area with branching fibers on the left" "The densely stained area adjacent to the branching fibers on the left" "The area with parallel lines at the bottom right" "The region with smaller, round cells with nuclei on the right" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/658.jpg" -"659" "What type of tissue is indicated by the right arrow, considering cell density and extracellular matrix?" "Cartilaginous tissue" "Dense irregular connective tissue" "Loose connective tissue" "Adipose tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/659.jpg" -"660" "Identify the process occurring at the site indicated by the up arrow?" "Adipose tissue atrophy" "Bone atrophy" "Inflammation of connective tissue" "Bone transformation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/660.jpg" -"661" "What is the most likely appearance of the cells indicated by the arrowheads within the renal glomerulus?" "Necrotic cells with significant karyorrhexis" "Hypercellular with crescent formation" "Hypocellular with evidence of scar tissue" "Cells with vacuolated cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/661.jpg" -"662" "What cellular morphology can be identified within the capillaries of the glomerulus?" "Podocytes" "Erythrocytes" "Mesangial cells" "Decoy cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/662.jpg" -"663" "Based on the overall tissue morphology, which of the following best describes the tissue reaction?" "Granulomatous inflammation" "Fibrotic response" "Chronic inflammatory response" "Acute inflammatory response" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/663.jpg" -"664" "Which histological feature suggests the presence of proliferative activity within the inflammatory process?" "Scattered larger open structured areas" "Area with fewer cells, possibly related to edema" "Pinkish to eosinophilic background" "Hyperchromatic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/664.jpg" -"665" "What is the predominant staining characteristic of the myelin sheaths observed in the nerve fibers of this image?" "Pinkish strands" "Reddish bodies" "Dark blue or purple" "Greenish hue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/665.jpg" -"666" "Based on the histological features, what type of cellular differentiation is suggested by the structures indicated by the arrows?" "Neurogenic differentiation" "Adipocytic differentiation" "Myogenic differentiation" "Primitive follicular differentiation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/666.jpg" -"667" "What is the characteristic appearance of the extracellular matrix within this tissue sample?" "Hyaline and glassy" "Calcified and lamellated" "Pink and collagenous" "Myxoid and loose" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/667.jpg" -"668" "Based on the cellular morphology observed, what type of inclusion can be seen within the cytoplasm of the neurons?" "Hirano bodies" "Lipofuscin granules" "Neuronal cytoplasmic inclusions" "Lewy bodies" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/668.jpg" -"669" "Which of the following best characterizes the glands present in this tissue section?" "Serous-secreting glands with basophilic granules" "Endocrine glands with dense eosinophilic secretions" "Mucous-secreting glands with clear cytoplasm" "Sebaceous glands with lipid-rich vesicles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/669.jpg" -"670" "Based on the staining intensity, which tissue sample shows a higher level of Bax protein expression?" "Right side of the image" "Both sides are equally stained" "Left side of the image" "Neither side shows Bax protein expression" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/670.jpg" -"671" "Based on the nuclear characteristics observed in the image, which of the following is associated with the cells?" "Hyperchromasia indicating increased DNA content" "Prominent nucleoli in most cells" "Monotonous nuclear sizes with rare variations" "Uniformly dispersed chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/671.jpg" -"672" "Analyzing the stromal tissue visible in the image, how does its cellular composition compare to the duct-like structures?" "The stromal tissue appears more densely packed with cells" "Both the stromal tissue and duct-like structures show similar cellularity" "There is an absence of nuclei in the stromal tissue" "The stromal tissue has fewer nuclei and is less cellular" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/672.jpg" -"673" "What can be inferred about the inflammatory infiltrate observed in this tissue section?" "Largely filled with eosinophils" "Made up mostly of lymphocytes" "Composed predominantly of neutrophils" "Predominantly macrophages" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/673.jpg" -"674" "Analyzing the nuclei, what can be inferred about their appearance?" "The nuclei are hyperchromatic with clumped chromatin" "All nuclei contain single, inconspicuous nucleoli" "The nuclei appear vesicular with a clear chromatin pattern" "The nuclei are small with dense chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/674.jpg" -"675" "Considering the staining properties, how does most of the cytoplasm appear in these cells?" "Amphophilic, suggesting a variable composition" "Acidophilic, suggesting a low pH environment" "Eosinophilic, implying a high content of cytoplasmic proteins" "Basophilic, indicating a high RNA content" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/675.jpg" -"676" "What feature of the tissue architecture is suggested by the presence of lobules separated by thin fibrous septae?" "Well-organized and circumscribed nodules typical of benign tissue." "Well-differentiated glandular formation typical of healthy tissue." "Lobular structure with evidence of disorganized growth." "Disorganized growth pattern without clear architecture." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/676.jpg" -"677" "Which type of staining is primarily exhibited by the extracellular matrix within this tissue sample?" "Hematoxylin-only staining" "Hematoxylin and Eosin staining" "Eosin-only staining" "Periodic Acid-Schiff staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/677.jpg" -"678" "The presence of cells with increased nuclear-to-cytoplasm ratio in a disorganized pattern primarily indicates:" "Adipose tissue deposition" "Active regeneration of tissue" "Mesothelial hyperplasia" "Chronic inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/678.jpg" -"679" "What type of epithelium is predominantly visible on the right side of the image indicated by the arrows?" "Pseudostratified columnar epithelium" "Stratified squamous epithelium" "Simple squamous epithelium" "Simple columnar epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/679.jpg" -"680" "What is the predominant staining characteristic of the collagen-rich fibrous tissue visible in the image?" "Dense pink staining" "Light blue to purple hue" "Red to orange shade" "Greenish-yellow coloration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/680.jpg" -"681" "What is the composition of the material that appears to encapsulate the structures indicated by the 'G' labels?" "Dense connective tissue" "Smooth muscle fibers" "Hyaline cartilage" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/681.jpg" -"682" "Based on the structure and organization of the tissue, what is the most probable anatomical origin of this section?" "Cardiac muscle tissue" "Dermis of the skin" "Liver parenchyma" "Renal cortex" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/682.jpg" -"683" "Based on the microscopic image of the tissue provided, what is the predominant staining color of the extracellular matrix?" "Pink" "Green" "Red" "Blue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/683.jpg" -"684" "Analyzing the morphology of the cells surrounding the follicular structures, how would you describe their nuclear shape?" "Circular" "Irregular" "Triangular" "Elongated" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/684.jpg" -"685" "What feature of the nuclei of larger cells in the image is pertinent?" "They are generally centrally placed" "They are eccentrically placed" "They exhibit a doughnut shape" "They are multilobed" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/685.jpg" -"686" "What staining characteristic is predominant in the tissue section observed under the microscope at 200x magnification?" "Magenta to purple hues characteristic of PAS positivity" "Dark blue to purple nuclei typical of Hematoxylin staining" "Green to blue staining suggestive of collagen fibers" "Brown to black granules indicative of melanin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/686.jpg" -"687" "Based on the cellular morphology observed, what feature is characteristic of the nuclei within the densely packed cells?" "Anisokaryosis" "Uniform nuclear size and shape" "High mitotic rate" "Multinucleation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/687.jpg" -"688" "By examining the tissue structure and the staining pattern, which connective tissue element can be identified in the image?" "Adipose tissue" "Hyaline cartilage" "Collagenous fibers" "Skeletal muscle" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/688.jpg" -"689" "What can be inferred about the small, round, eosinophilic cells without prominent nuclei within the small blood vessels?" "Lymphocytes" "Erythrocytes" "Neutrophils" "Platelets" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/689.jpg" -"690" "Evaluating the central area in the image, what is the most likely composition of the darkly stained structures?" "Aggregated neoplastic cells" "Dense microbial colonies" "Clusters of erythrocytes" "Focal accumulations of melanin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/690.jpg" -"691" "What pathological process is suggested by the increased number of highlighted blood vessels in the perisinusoidal spaces and portal areas?" "Normal liver vasculature" "Steatohepatitis" "Hepatic fibrosis" "Portal hypertension" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/691.jpg" -"692" "Based on the morphology of the epithelial cells lining the duct-like structures, which cellular arrangement is most accurately depicted in this image?" "Simple squamous epithelium" "Pseudostratified columnar epithelium" "Simple cuboidal epithelium" "Stratified squamous epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/692.jpg" -"693" "Based on the immunohistochemistry (IHC) staining pattern, which cellular marker is most likely being indicated by the brown coloration in this tissue section?" "CD10 protein" "Prostate-specific antigen" "Hsp27 protein" "Estrogen receptor" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/693.jpg" -"694" "Within the epidermis, what pattern of inflammatory cell infiltrate is discernible?" "Predominantly basal cell layer localization" "Dense aggregates disrupting normal architecture" "A superficial perivascular distribution" "Scattered individual cell infiltration without disruption" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/694.jpg" -"695" "Observing the morphology and arrangement of the cells in this tissue, what is the most likely diagnosis?" "Glioblastoma" "Lipoma" "Adenocarcinoma" "Spindle cell sarcoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/695.jpg" -"696" "Based on the microscopic features observed in this image, which of the following characteristics does the tumor likely possess?" "A desmoplastic reaction" "A leukocytic infiltration" "Extensive necrosis" "A high degree of vascularization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/696.jpg" -"697" "Based on the staining characteristics and morphology, what type of tissue is most likely represented in this image?" "Smooth muscle tissue" "Nervous tissue" "Adipose tissue" "Skeletal muscle tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/697.jpg" -"698" "Considering the morphology of the nuclei, which description accurately details their appearance in this histological image?" "Large nuclei with prominent nucleoli" "Hyperchromatic and pleomorphic nuclei" "Elongated or cigar-shaped nuclei" "Round nuclei with multiples nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/698.jpg" -"699" "Based on the histopathological features observed in the image, what is the most likely diagnosis?" "Well-differentiated liposarcoma" "Dedifferentiated liposarcoma" "Myxoid liposarcoma" "Pleomorphic liposarcoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/699.jpg" -"700" "What characteristic feature is evident in the endothelial lining of the vascular spaces?" "Endothelial cells have minimal cytological atypia" "Endothelial cells show uniform hyperchromasia" "Endothelial cells are well-organized and uniform" "Endothelial cells are prominent and contribute to the irregular appearance of the vascular spaces" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/700.jpg" -"701" "Which cell type can predominantly be observed scattered throughout the stromal component of the tissue?" "Neutrophils" "Eosinophils" "Macrophages" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/701.jpg" -"702" "Based on the nuclear characteristics of the cells in the image, which of the following best describes the observed nuclei?" "Large, euchromatic nuclei with prominent nucleoli" "Uniform, small nuclei with finely dispersed chromatin" "Small, hyperchromatic nuclei with smooth regular contours" "Large, hyperchromatic nuclei with irregular contours" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/702.jpg" -"703" "What histological feature is indicated by the arrow in the image?" "Lymphoid aggregates within the stroma" "A cluster of typical alveolar macrophages" "The presence of a mucinous adenocarcinoma" "Evidence of squamous epithelial cell differentiation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/703.jpg" -"704" "Which of the following cells are prominently featured in this tissue section as part of the inflammatory response?" "Giant cells with multiple nuclei arranged in a horseshoe pattern" "Eosinophils with bilobed nuclei and prominent granules" "Small cells with dark staining, segmented nuclei" "Mesenchymal cells with spindle-shaped nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/704.jpg" -"705" "Analyzing the morphology of the lightly stained cells around the brown-stained structure, what is the most probable identity of these cells based on their shape?" "Fibroblasts" "Hepatocytes" "Kupffer cells" "Endothelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/705.jpg" -"706" "Based on the immunohistochemical staining pattern observed in the image, which organelle in the cells is most likely the predominant location of the targeted marker?" "Nucleus" "Golgi apparatus" "Cytoplasm" "Mitochondria" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/706.jpg" -"707" "Observing the tissue organization in the image, what type of epithelial arrangement is most likely represented?" "Simple columnar" "Transitional" "Pseudostratified" "Stratified squamous" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/707.jpg" -"708" "Judging from the staining pattern and morphology of the cells, what is the probable immunohistochemical marker used in this staining and what does its expression suggest about the tissue's origin?" "Vimentin, indicating mesenchymal origin" "CD20, indicating lymphoid origin" "Cytokeratin 7, suggesting origin from specific glandular epithelia" "Cytokeratin 5, indicating squamous epithelial origin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/708.jpg" -"709" "Based on the presence of cellular disintegration and loss of cell detail, what pathological process can be identified in this tissue section?" "Fatty necrosis" "Caseous necrosis" "Acute ischemic necrosis" "Coagulative necrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/709.jpg" -"710" "What can be inferred about the tissue structure from the empty spaces observed in the tissue section?" "Occurrence of cystic changes" "Presence of fat cells" "Artifacts from tissue processing" "Previous sampling sites" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/710.jpg" -"711" "Given the observed characteristics in the image, what can be inferred about the cell density in the provided sample?" "Sparsely distributed cells with abundant extracellular matrix" "Densely packed cells with minimal intercellular space" "Normal cell density with ample intercellular space" "Cells arranged in a loose reticular pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/711.jpg" -"712" "What does the appearance of clear, halo-like perinuclear zones in the upper layers of the epidermis suggest?" "Evidence of koilocytosis" "Keratinocyte maturation defect" "Dyskeratotic cells" "Presence of melanocytic nevi" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/712.jpg" -"713" "Based on the cellular pathology presented in the image, what is the most likely diagnosis?" "Verruca vulgaris" "Basal cell carcinoma" "Inflammatory dermatitis" "Malignant melanoma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/713.jpg" -"714" "What cellular feature is indicated by the black arrows in the image?" "Hemosiderin deposition" "Intracytoplasmic melanin" "Lipofuscin granules" "Erythrocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/714.jpg" -"715" "Within this tissue section, how can you differentiate between apocrine and sebaceous glands?" "Apocrine glands are larger and have a more irregular shape than sebaceous glands" "Sebaceous glands are associated with blood vessels rather than hair follicles" "Apocrine glands have a more tubular structure compared to the spongy appearance of sebaceous glands" "Sebaceous glands are larger and have a more irregular shape than apocrine glands" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/715.jpg" -"716" "Based on the arrangement of cells and spaces in the tissue, what is the likely magnification of this image?" "100×" "40×" "400×" "200×" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/716.jpg" -"717" "What type of tissue background and extracellular material can be discerned from the eosinophilic staining in this microscopic view?" "Skeletal muscle" "Dense hyaline cartilage" "Connective tissue" "Myxoid matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/717.jpg" -"718" "What is the arrangement of the epithelioid cells observed in the granuloma?" "Forming well-defined tight aggregates" "Loosely dispersed throughout the stroma" "Isolated and scattered among lymphocytes" "Predominantly surrounding areas of necrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/718.jpg" -"719" "What feature is notably absent among the epithelioid cells in the granuloma?" "Central area of caseous necrosis" "Multinucleated giant cells" "Eosinophilic cytoplasm" "Peripheral rim of lymphocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/719.jpg" -"720" "How would you describe the cytoplasm of the epithelioid histiocytes in comparison to the surrounding cells?" "Transparent and unstained" "More basophilic" "More eosinophilic" "Less eosinophilic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/720.jpg" -"721" "Based on the morphology observed, which type of cells are most likely represented by the brown-stained cells in the image?" "Hepatocytes" "Lymphocytes" "Neutrophils" "Erythrocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/721.jpg" -"722" "Analyzing the morphology of the cells in the glomerular tuft, which of the following features can be identified?" "Swelling of endothelial cells" "Infiltration of inflammatory cells" "Atrophy of endothelial cells" "Hyperplasia of epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/722.jpg" -"723" "What is the predominant nuclear feature seen in the cells within this microscopic image?" "Vesicular chromatin" "Frequent binucleation" "Prominent nucleoli" "Evenly dispersed chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/723.jpg" -"724" "What feature in this skin tissue section suggests a high cytoplasmic volume relative to the nuclei?" "Cytoplasm with granular texture" "Presence of small, dark-staining granules in the cytoplasm" "Cytoplasm with a fibrous appearance" "Cytoplasm appears pale staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/724.jpg" -"725" "In the microscopic view, which staining characteristic is most evident in the cytoplasm of the giant cell?" "Basophilic staining appearing as a light blue hue" "Eosinophilic staining appearing as a fainter purple hue" "Eosinophilic staining appearing as a dark purple hue" "Basophilic staining appearing as a dark black hue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/725.jpg" -"726" "Which layer of the epidermis is prominently separated from the underlying layer in this histopathological image?" "Stratum spinosum" "Stratum basale" "Stratum corneum" "Stratum granulosum" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/726.jpg" -"727" "Based on evaluating the epithelial layer morphology in this microscopic image, which feature is absent?" "Inflammatory infiltrate" "Stratum lucidum layer" "Clear delineation between the layers of epidermis" "Parakeratosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/727.jpg" -"728" "What is the predominant feature of the cells within the dense aggregates surrounding the round structures?" "Abundant cytoplasm with secretory granules" "Multinucleated giant cells" "Prominent nucleoli within the nuclei" "High nucleus-to-cytoplasm ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/728.jpg" -"729" "Based on the image, what is the most likely identity of the central light-staining areas within the round structures?" "Epithelial inclusion cysts" "Necrotic tissue" "Blood vessel lumens" "Collagen bundles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/729.jpg" -"730" "What is the appearance of the cells outside the perivascular aggregates?" "Densely packed cells with large, hyperchromatic nuclei" "Smaller cells with a high cytoplasm-to-nucleus ratio" "Isolated cells with no visible nucleus" "Larger cells with significant amount of purple cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/730.jpg" -"731" "Which feature best describes the nuclear characteristics of the cells observed in this tissue section stained with Hematoxylin-Eosin?" "Hyperchromatic nuclei with high nuclear-to-cytoplasmic ratio" "Single prominent nucleoli" "Uniform nuclear size and shape" "Monotonous nuclear appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/731.jpg" -"732" "What conclusion can be drawn about the mitotic activity within this tissue sample?" "There are no visible mitotic figures within the tissue" "Mitotic figures are rare and difficult to identify" "Mitotic figures are abundant and atypical" "Mitotic activity is present but appears normal" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/732.jpg" -"733" "What distinctive nuclear feature can be observed in several cells within this image?" "Circumscribed nucleoli with perinucleolar halos" "Nuclear grooves and indentations" "Multilobed nuclei with the formation of nuclear bridges" "Binucleation with homogenous nuclear distribution" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/733.jpg" -"734" "What does the presence of cells with eccentric, plasmacytoid-like nuclei suggest when observed in a histopathological slide like in the provided image?" "They represent normal differentiation of cells." "They imply that the tissue is undergoing regeneration." "They are indicative of high-grade neoplastic processes." "They suggest the presence of an inflammatory response." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/734.jpg" -"735" "What distinctive morphological feature of the cells indicated by the arrows can be observed under hematoxylin and eosin staining in this tissue section?" "Multiple, peripherally located nuclei forming a horseshoe-like pattern" "Multiple, centrally located nuclei with scant cytoplasm" "A single, hyperchromatic nucleus occupying most of the cellular space" "A single, central nucleus with vacuolated cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/735.jpg" -"736" "Based on the image, which observation can be made about the cellular background surrounding the giant cells indicated by the arrows?" "The background includes mononuclear inflammatory cells with ample cytoplasm" "The background shows a high concentration of erythrocytes, indicating hemorrhage" "The background predominantly features acellular collagenous stroma" "The background is composed of adipocytes with a signet ring appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/736.jpg" -"737" "What feature is most consistent with the nuclei of the cells shown in the microscopic image?" "Anisonucleosis with prominent nucleoli" "Dense chromatin with inconspicuous nucleoli" "Multinucleated cell formation" "Uniform nuclear size and shape" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/737.jpg" -"738" "Which component appears less abundant in this granulation tissue when assessed by the red staining pattern?" "Collagen" "Hyaluronic acid" "Fibrin" "Elastin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/738.jpg" -"739" "What is the predominant nuclear characteristic observed in these cells?" "Small, uniformly shaped nuclei" "Bi-nucleated cells" "Nuclei with condensed chromatin" "Large, irregularly shaped nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/739.jpg" -"740" "Within the capillary loops of the glomeruli, what morphological feature can be observed that is associated with pathology?" "Lucent deposits" "Erythrocytes within capillaries" "Pinkish microthrombi" "Clear capillary lumens" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/740.jpg" -"741" "Based on the image, which description most accurately corresponds to the appearance of the glomerulus on the left side?" "The glomerulus appears relatively unaffected" "It shows the presence of hypercellularity" "There is evidence of significant scarring" "It displays prominent neutrophil infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/741.jpg" -"742" "What does the histological architecture of the cells suggest about the tissue?" "Disorganized neoplastic growth" "Highly organized glandular tissue" "Benign reactive proliferation" "Normal physiological cell turnover" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/742.jpg" -"743" "What phenomenon is indicated by the arrow in the microscopic image?" "Karyolysis" "Karyorrhexis" "Apoptotic body formation" "Emperipolesis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/743.jpg" -"744" "Identify the structure characterized by a wavy appearance and situated immediately outside the endothelial layer." "Internal elastic lamina" "Collagen fibers" "Smooth muscle cells" "External elastic lamina" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/744.jpg" -"745" "What is the predominant subcellular localization of the positive immunostaining observed in this tissue section?" "Cell membrane" "Extracellular matrix" "Nuclei" "Cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/745.jpg" -"746" "How would you describe the distribution of the positively stained cells within the tissue section?" "Clustered in Specific Regions" "Localized to the Periphery" "Uniformly Distributed" "Scattered Throughout" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/746.jpg" -"747" "Based on the cellular arrangement visible under the thin black arrow, which of the following best describes the morphological characteristic of the organism?" "Spirochetes with helical shape" "Bacilli arranged in chains" "Cocci arranged in tetrad formation" "Cocci arranged in cubical packets" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/747.jpg" -"748" "Focusing on the microorganism pointed out by the thick blue arrow, which feature is present?" "Cocci arranged in irregular clusters" "Uniformly dispersed filamentous structures" "Presence of bifurcating mycelial structures" "Elongated bodies with no visible flagella" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/748.jpg" -"749" "Based on the image, which type of cells appear to be the predominant component in this field of view?" "Eosinophilic epithelial cells" "Fibroblasts with spindle-shaped morphology" "Cells with abundant cytoplasm" "Lymphocytes with dark staining nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/749.jpg" -"750" "Evaluating the underlying stroma, which type of inflammatory cells appears to be predominating?" "Neutrophils" "Macrophages" "Eosinophils" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/750.jpg" -"751" "What can be inferred about the vascularity of the tissue from this microscopic image?" "Blood vessels exhibit thrombi within their lumens" "Blood vessels show signs of sclerosis" "Blood vessels appear engorged with erythrocytes" "Blood vessels are sparse and inconspicuous" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/751.jpg" -"752" "Considering the widespread cytoplasmic brown staining and the cell density, which statement best describes the nature of the tissue observed?" "The tissue shows features suggestive of a diffuse pattern of antigen expression typical of a tumor" "The tissue is characteristic of an inflammatory lesion" "The tissue is likely a normal, non-neoplastic section" "The tissue appears to be a high-grade, undifferentiated neoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/752.jpg" -"753" "How does the cellular arrangement in the insert compare to the typical architecture of malignant neoplastic tissue?" "It demonstrates features typical of malignancy" "It shows the lack of clear demarcation between cell layers" "It resembles disorganized growth with varying cell densities" "It reflects an organized structure without evidence of neoplasia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/753.jpg" -"754" "What is the predominant staining color of the seminiferous tubules' tunica propria in this image?" "Purple" "Pink" "Green" "Red" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/754.jpg" -"755" "What is the morphological appearance of the matrix observed in the image?" "Pale and loosely arranged" "Dense and fibrous" "Homogenous and calcified" "Darkly stained and compact" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/755.jpg" -"756" "How would you characterize the vascular structures present within the matrix?" "Show signs of thrombosis or occlusion" "Contain red blood cells and have clearly delineated walls" "Have thick, hyalinized walls" "Are absent or not visible" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/756.jpg" -"757" "What is the main characteristic of the material indicated by the star mark in the subendothelial space of the glomerulus?" "Clearly fibrillar structure" "Predominantly hypercellular" "Hyaline deposits" "Homogenous, eosinophilic appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/757.jpg" -"758" "What can be inferred about the tubules surrounding the glomerulus in this image?" "They contain homogenous pink secretions suggesting proteinaceous material" "They are devoid of any visible abnormalities" "They are dilated and lined with hyperplastic epithelium" "They display signs of significant atrophy and fibrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/758.jpg" -"759" "What morphologic feature is indicated by the black arrowheads in the salivary gland tissue?" "Multinucleation" "Intranuclear inclusion bodies" "Russell bodies" "Intracytoplasmic eosinophilic inclusions" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/759.jpg" -"760" "Based on the morphological changes observed, what is a likely diagnosis for the salivary gland condition depicted in this image?" "Cytomegalovirus infection" "Mucocele formation" "Chronic sialoadenitis" "Sjogren's syndrome" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/760.jpg" -"761" "Based on the nuclear staining pattern and tissue architecture, which neoplastic condition might this histological image correspond to?" "Glioblastoma multiforme" "Well-differentiated liposarcoma" "Renal cell carcinoma" "Hepatocellular carcinoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/761.jpg" -"762" "Considering the staining characteristics of the image, which immunohistochemical marker is most likely being demonstrated in the positively stained cells?" "CK7" "CD3" "CD45" "HepPar-1" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/762.jpg" -"763" "Observing the stroma surrounding the cellular infiltration, what is its staining characteristic in this H&E stained section?" "Heavily eosinophilic and fibrous" "Deeply basophilic" "Lightly eosinophilic" "Strongly PAS positive" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/763.jpg" -"764" "Considering the overall cellularity of the marrow depicted in the image, which condition does it most likely represent?" "Normal cellularity for a young adult" "Hypocellular bone marrow" "Normal cellularity for an elderly adult" "Hypercellular bone marrow" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/764.jpg" -"765" "What morphological feature distinguishes the cells suspected to be ganglion cells in this image from surrounding tissue?" "The cells have less cytoplasm compared to the surrounding cells" "The cells lack clearly defined nuclear boundaries" "The size of the cells is smaller than the cells in the surrounding tissue" "The cells demonstrate an intensely stained cytoplasm and nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/765.jpg" -"766" "What feature is highlighted by the Periodic acid Schiff (PAS) staining in this glomerulus?" "Decrease in extracellular matrix" "Hypercellularity of the glomerular tuft" "Proliferation within glomerular capillary loops" "Sclerosis and structure of the crescents" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/766.jpg" -"767" "What do the regions with cells having dense, dark purple nuclei suggest when assessing for cellular features in this image?" "Presence of cellular material indicative of viable tissue" "Presence of inflammatory cells" "Eosinophilic cytoplasmic staining" "Tubular dilation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/767.jpg" -"768" "Based on the staining characteristics, what does the presence of more eosinophilic staining in certain areas most likely indicate?" "Carbohydrate stores within the cells" "High lipid content within the cells" "Presence of nucleic acids" "Proteinaceous material corresponding to reabsorption droplets" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/768.jpg" -"769" "What does the area with less cellularity and staining seen in the central region of the image likely represent?" "A stromal or acellular area" "An area of necrotic tissue" "A region rich in neoplastic cells" "A section of normal, healthy tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/769.jpg" -"770" "In the histological image, what does the appearance of the collagen fibers in the dermis indicate?" "Normal collagen distribution" "Evidence of skin hydration" "Thickened and densely packed collagen" "Possible inflammatory process" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/770.jpg" -"771" "What is the predominant architectural feature observed in the cells of this microscopic image?" "Palisading arrangement" "Rosette formation" "Necrosis" "Whorled pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/771.jpg" -"772" "What may the areas of increased eosinophilicity, as indicated by arrows in the image, suggest?" "Acute inflammation" "Hemorrhage" "Edema" "Calcifications" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/772.jpg" -"773" "Considering the morphological features, what is the likely grade of the tumor shown in the image?" "Grade I neoplasm" "High-grade malignancy" "Grade II neoplasm" "Pre-malignant lesion" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/773.jpg" -"774" "Based on the morphology shown in the image, which cellular structure is prominently indicated by the arrows?" "Red blood cells" "Lymphocytes" "Megakaryocytes" "Sinus lining cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/774.jpg" -"775" "What differentiates panel (d) from panels (b) and (c) in terms of immunoreactivity?" "Strong, diffuse green staining in cellular matrix" "Brown staining confined to a minority of cells suggesting glandular structures" "Universal strong brown staining throughout all cells" "No visible brown staining in any cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/775.jpg" -"776" "Based on the cellular morphology, which type of cells can be identified in the lighter stained areas where individual cell nuclei are visible?" "Fibroblasts or smooth muscle cells" "Endothelial cells" "Adipocytes" "Keratinocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/776.jpg" -"777" "Observing the tissue architecture and cell morphology, what signs are notably absent in this histological section?" "Lymphocytic infiltration" "Malignancy" "Blood vessels" "Necrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/777.jpg" -"778" "Based on the cellular morphology shown in the image, what is the characteristic feature of the nuclei in some hepatocytes?" "Hyperchromatic nuclear staining" "Nuclear pleomorphism" "Multinucleation" "Cytoplasmic clearing around the nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/778.jpg" -"779" "Based on the staining characteristics and cellular morphology observed in the image, which cellular component appears to be less prominent?" "Cytoplasm" "Nucleoli" "Nuclei" "Cell membrane" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/779.jpg" -"780" "Considering the overall cleanliness of the background and presence of cells, which description best fits the status of the cytology smear background?" "Moderately cluttered with extracellular material with some visible cell details" "Cluttered with high amounts of extracellular debris and blood" "Completely clean with no visible extracellular material or cells" "Clean with minimal debris or extracellular material" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/780.jpg" -"781" "Based on the appearance of the chromatin pattern within the cell nuclei, how would the chromatin be characterized?" "Open with a lighter appearance in the center and denser at the periphery" "Diffusely distributed with an overall dark staining" "Hypercondensed and uniformly dark" "Clumped at the periphery with clearing at the center" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/781.jpg" -"782" "What feature is indicated by the solid arrows in the microscopic image?" "Inflammatory cell infiltration" "Brush border disruption" "Mitotic figures" "Irregular, flattened cell shapes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/782.jpg" -"783" "Based on the presence of the features indicated by the arrows, what is the most likely pathology represented in the image?" "Chronic inflammation" "Granulomatous disease" "Benign neoplastic growth" "Acute tubular injury" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/783.jpg" -"784" "Based on the cellular organization, what is the predominant architectural feature observed in the gland-like structures?" "Uniform, well-delineated acini" "Regular duct-like formations" "Irregular and crowded glandular structures" "Homogeneous distribution of cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/784.jpg" -"785" "What histological feature can be deduced from the cellular pattern within the blood vessel in the image?" "Neoplastic proliferation" "Arterial thrombosis" "Lymphocytic infiltration" "Myxoid degeneration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/785.jpg" -"786" "Based on the morphology presented in the image, which feature best describes the chromatin pattern of the large cell with two nuclei?" "Homogenous and dense" "Light staining and vesicular" "Segregated and marginalized" "Hyperchromatic and clumped" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/786.jpg" -"787" "Which cellular component is predominantly visible in the stratified epithelial layer of this tissue sample?" "Cells with large cytoplasmic lipid droplets" "Anucleate squamous cells indicative of a superficial layer" "Cells with basophilic nuclei and clear cytoplasmic boundaries" "Keratinized cells with abundant eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/787.jpg" -"788" "Based on the staining pattern within the stroma, what might be indicated by the areas of dense, darker staining?" "Accumulation of hemosiderin-laden macrophages or blood breakdown products" "Aggregates of elastin fibers" "High concentration of cytoplasmic proteins" "Concentration of collagen bundles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/788.jpg" -"789" "Examining the overall morphology of the cells, what can be inferred about their size and shape?" "Monomorphic with little variation in size and shape" "Hyperchromatic with notable cell enlargement" "Anisocytic with predominantly elongated cells" "Pleomorphic with varying sizes and shapes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/789.jpg" -"790" "Based on the observed cellular morphology, which of the following features is NOT characteristic of the cells in this image?" "High nucleo-cytoplasmic ratio" "Clock-face chromatin pattern" "Predominantly centrally located nuclei" "Binucleation and multinucleation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/790.jpg" -"791" "Based on the cellular morphology seen in the image, what type of inflammatory response is indicated in the thyroid tissue?" "Autoimmune reaction without significant cellular infiltration" "Acute inflammatory response with dominant neutrophil infiltration" "Chronic inflammatory response with formation of granulomas" "Allergic reaction with eosinophil predominance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/791.jpg" -"792" "Based on the nuclear features observed in the spindle cells, what type of chromatin pattern can be seen?" "Vesicular chromatin with prominent nucleoli" "Finely dispersed chromatin" "Multinucleated chromatin" "Hyperchromatic nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/792.jpg" -"793" "Based on the histopathological features observed, what is the likely degree of dysplasia present in the stratified squamous epithelium?" "Full-thickness dysplasia" "Severe dysplasia" "Mild dysplasia" "Moderate dysplasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/793.jpg" -"794" "The round structures with densely-stained cells suggest the presence of which of the following features in connective tissue?" "Blood vessels with perivascular cellular infiltrates" "Sebaceous glands" "Cartilage islets" "Hair follicles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/794.jpg" -"795" "Based on the abundance of cytoplasm observed in the large cells with polygonal shape, what is the most likely intensity level of HMB-45 antigen staining visible in this image?" "Moderate" "Negligible" "Absent" "Strong" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/795.jpg" -"796" "Considering the upper part of the image, which type of immune cells can be identified based on size, chromatin appearance, and cytoplasmic characteristics?" "Lymphocytes and plasma cells" "Monocytes and fibroblasts" "Eosinophils and macrophages" "Lymphocytes and neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/796.jpg" -"797" "What is the histological feature indicated by the arrow in the image?" "Gastrointestinal stromal tumor with spindle cells" "Adenocarcinoma with desmoplastic reaction" "Hyperplastic polyp with increased glandular cells" "Endometriosis with typical gland and stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/797.jpg" -"798" "Based on the tissue morphology, what is the likely origin of the smooth muscle fibers observed?" "Muscularis mucosae of the intestinal tract" "Muscularis propria of the bowel wall" "Uterine myometrium" "Bladder detrusor muscle" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/798.jpg" -"799" "What characteristic feature is observed in the majority of cells in this image?" "Cells with 'clock face' chromatin pattern" "Multinucleated giant cells" "Koilocytes with perinuclear halos" "Signet ring cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/799.jpg" -"800" "In assessing the overall tissue architecture, what other structures are suggested by the elongated pink-staining areas?" "Remnants of connective tissue" "Smooth muscle fibers" "Erythrocyte aggregates" "Neoplastic spindle cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/800.jpg" -"801" "Based on the granularity observed in this image, what is the likely outcome of the immunohistochemical stain?" "Non-specific background staining" "Negative for protein-specific antigens" "Positive for protein-specific antigens" "Inconclusive due to poor stain penetration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/801.jpg" -"802" "Based on the nuclear staining pattern observed in the image, what is the most likely target of the immunohistochemical stain?" "HER2/neu" "Cytokeratin" "Estrogen receptor (ER)" "CD3" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/802.jpg" -"803" "Considering the high nuclear-to-cytoplasmic ratio exhibited by the cells in the image, what type of growth pattern is most consistent with the observed cellular morphology?" "Ductal carcinoma in situ" "Atypical hyperplasia" "Lobular carcinoma in situ" "Invasive ductal carcinoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/803.jpg" -"804" "Analyzing the extracellular matrix surrounding the clusters of cells, what is the most likely composition of the light blue material seen in the image?" "Fibrous stroma" "Hyaline cartilage" "Muscle tissue" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/804.jpg" -"805" "What is the most likely identity of the large cells with prominent nuclei indicated by asterisks?" "Adipocytes" "Cardiomyocytes" "Hepatocytes" "Neurons" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/805.jpg" -"806" "Based on the structure and arrangement of cells, what is the likely function of the smaller cells indicated by arrows?" "Immune response" "Structural support" "Signal transduction" "Nutrient storage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/806.jpg" -"807" "Considering the mesangial matrix expansion seen in this renal tissue section, which other changes are consistent with this pathology?" "Decreased number of mesangial cells within the expanded matrix." "The presence of hypercellularity in the mesangial areas." "Lightly stained mesangial regions indicating reduced protein content." "Unaffected mesangial regions with no expansion." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/807.jpg" -"808" "Identify the feature pointed out by the black arrow in this image." "Asteroid body" "Signet-ring cell" "Russel body" "Auer rod" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/808.jpg" -"809" "What is observed within some of the gland-like spaces that provides evidence of mucin production?" "Dense eosinophilic filamentous structures" "Red blood cells filling the spaces" "Pale, lightly staining areas within the spaces" "Dark blue patches consistent with calcification" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/809.jpg" -"810" "Based on the cellular morphological features observed in the image, which layer of the stratified squamous epithelium is most prominent at the top portion of this micrograph?" "Stratum spinosum" "Basal layer" "Stratum granulosum" "Stratum corneum" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/810.jpg" -"811" "Examining the clear, cell-free zone beneath the epithelial layer, what histological feature is most lacking compared to the other tissue zones in this image?" "Dense collagen deposition" "Abundant extracellular matrix" "High cellularity" "Presence of immune cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/811.jpg" -"812" "What tissue change is suggested by the eosinophilic staining patterns observed in this image?" "Tissue necrosis" "Adipose tissue accumulation" "Extensive fibrosis" "Active inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/812.jpg" -"813" "Focusing on the cell nuclei morphology within the tissue, what can be inferred about the possible nature of the tissue process?" "Hypochromatic nuclei with uniform size" "Anisonucleosis with drastic size variation" "Hyperchromatic nuclei with marked pleomorphism" "Hyperchromatic nuclei with modest variation in size and shape" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/813.jpg" -"814" "What staining technique is most likely used in this microscopic image of the tissue?" "Giemsa stain" "Hematoxylin and eosin stain" "Periodic Acid-Schiff stain" "Masson's trichrome stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/814.jpg" -"815" "What type of tissue primarily occupies the upper portion of this microscopic image?" "Epithelial tissue" "Connective tissue" "Muscular tissue" "Neural tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/815.jpg" -"816" "Based on the cellular structures seen at the bottom of the image, what is likely to be the identity of these cells?" "Keratinocytes" "Adipocytes" "Osteocytes" "Neurons" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/816.jpg" -"817" "What is the predominant staining characteristic of the hepatocyte cytoplasm in this liver tissue section?" "Basophilic (blue/purple)" "Eosinophilic (pink)" "Dark Brown" "Clear/unstained" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/817.jpg" -"818" "What can be inferred about the sinusoidal spaces between the hepatocytes in this tissue section?" "They are distended and hemorrhagic" "They are barely visible with subtle outlines" "They are occluded by thrombi" "They are clearly demarcated and empty" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/818.jpg" -"819" "What characteristic of the nucleoli within the lymphocytes can be used to evaluate a possible diagnosis?" "Multiple small nucleoli in each cell" "Absence of nucleoli in the majority of cells" "Conspicuous nucleoli in several cells" "Nucleoli with regular contours and even staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/819.jpg" -"820" "Based on the arrangement of the cells in the image, how would you characterize their cohesion?" "The cells appear in well-formed clusters" "Cells are uniformly spaced with consistent cell-to-cell contact" "The lymphocytes form rosettes around a central lighter staining area" "The cells display a dyscohesive pattern without forming clusters" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/820.jpg" -"821" "What feature best characterizes the area indicated by the red arrow?" "Uniform epithelial cells and luminal spaces" "Increased cellular and nuclear pleomorphism" "Lack of organized acinar structures" "Irregular clusters of neoplastic cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/821.jpg" -"822" "What is the nature of the cellular architecture at the location indicated by the blue arrow?" "Increased nuclear pleomorphism with invasive tendencies" "Partially filled ducts with uniform cells" "Abundant fibrous connective tissue" "Small, organized acini with uniform epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/822.jpg" -"823" "What do the eosinophilic deposits noted in the stromal interstitium and within the tubular epithelium likely represent?" "Hemorrhage" "Necrotic debris" "Lipid accumulations" "Calcium deposits" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/823.jpg" -"824" "Based on the staining patterns, which cell type shows a high level expression of the specific marker?" "Germ cells (GC)" "Cells of the tunica albuginea (TA)" "Sertoli cells (ST)" "Leydig cells (LC)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/824.jpg" -"825" "In the image, how do the germ cells (GC) compare to the Sertoli cells (ST) in terms of staining for the specific marker?" "Germ cells show less intense staining than Sertoli cells" "Germ cells show no staining at all while Sertoli cells are lightly stained" "Germ cells show more intense staining than Sertoli cells" "Germ cells and Sertoli cells both show equally intense staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/825.jpg" -"826" "What is the morphology of the nuclei in the cells indicated by the arrow?" "Uniformly shaped with multiple nucleoli" "Hyperchromatic, round and single nuclei" "Multinucleated with dispersed chromatin" "Bilobed with a 'coffee bean' appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/826.jpg" -"827" "What is the characteristic appearance of the nuclei in the smaller cells surrounding the histiocytes?" "Large, vesicular and centrally located" "Lightly stained with dispersed chromatin" "Smaller with densely stained chromatin" "Fragmented and variably sized" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/827.jpg" -"828" "What type of inflammatory cell infiltration predominates in the submucosal layer of this tissue sample?" "Predominantly neutrophils" "Predominantly lymphocytes" "Predominantly eosinophils" "Predominantly macrophages" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/828.jpg" -"829" "Analyzing the overall tissue architecture, which type of tissue does the sample most likely represent?" "Connective tissue" "Epithelial tissue" "Nervous tissue" "Muscular tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/829.jpg" -"830" "What is the predominant architectural pattern observed in this tissue sample?" "Cribiform" "Pseudoglandular" "Micropapillary" "Solid nests" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/830.jpg" -"831" "Based on the cytoplasmic features of the cells observed in this tissue sample, how would you describe the amount of cytoplasm per cell?" "Scant" "Abundant" "Moderate" "Sparse" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/831.jpg" -"832" "What morphological feature is indicated by the black arrow in the image of the liver tissue section?" "Hepatocellular carcinoma" "Bile stasis" "Inflammatory cell infiltration" "Hepatic necrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/832.jpg" -"833" "Based on the clustering of cells with dense nuclei at the site of the blue arrow, which histological structure is likely to be identified in this area?" "Cancer metastasis" "Hepatic lobule" "Lipid droplet" "Granuloma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/833.jpg" -"834" "What does the region pointed to by the green arrow in the image suggest about the extracellular matrix?" "Hyaline change" "Amyloid deposition" "Normal collagen deposition" "Bridging fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/834.jpg" -"835" "What is the primary morphological feature observed in the fungal structures within the inset GMS-stained portion of the image?" "Budding morphology typical of yeast reproduction" "Sporulation with distinct conidia" "Hyphal elements with widespread mycelial growth" "Basidia with attached basidiospores" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/835.jpg" -"836" "What does the morphology of the tubular structures most closely resemble?" "Normal renal tubules" "Artefactual tissue distortion" "Amyloid deposits" "Malignant neoplastic infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/836.jpg" -"837" "Based on the irregular appearance of the tissue architecture, what is a potential pathological process at play?" "Amyloidosis" "Advanced diabetic nephropathy" "Acute tubular necrosis" "Glomerulonephritis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/837.jpg" -"838" "What can be inferred about the potential inflammatory response in this tissue based on the cellular characteristics?" "Aggregates of cells with darkly stained nuclei" "Presence of well-differentiated lymphocytes and plasma cells" "Absence of inflammatory cells" "Neutrophils are the predominant inflammatory cell type" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/838.jpg" -"839" "In image A, what is the predominant staining characteristic of the squamous epithelium layer?" "Intense brown staining with Golgi zone accentuation" "Homogeneous light blue staining throughout the tissue" "Sparse brown staining throughout the tissue" "Punctate staining patterns near the nucleus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/839.jpg" -"840" "Analyzing the density of cells and the connective tissue stroma, what condition does NOT appear to be present in the viewed pancreatic tissue?" "Inflammation" "Severe necrosis" "Edema" "Extensive fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/840.jpg" -"841" "Considering the structures present in the dermal layer, what finding would be consistent with the ongoing reactive or reparative process?" "Scattered adipocytes" "Collagen arranged in a concentric pattern around a hair follicle" "Smooth muscle bundles" "Dense aggregates of neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/841.jpg" -"842" "Based on the arrangement of the acinar glands observed in the image, which of the following best describes the pattern present?" "Highly organized and uniform" "Loosely dispersed with ample stroma" "Disorganized and haphazard" "Radially oriented with converging ducts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/842.jpg" -"843" "Considering the presence of intraluminal content within the glands, which type of secretion does the eosinophilic (pink) material most likely represent in this H&E-stained section?" "Lipid-rich sebum" "Proteinaceous material" "Glycogen deposits" "Mucinous secretion" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/843.jpg" -"844" "In which section can one observe evidence of a desmoplastic reaction characterized by the presence of pink-staining collagen fibers throughout the tissue?" "Section A" "Section C" "Section B" "" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/844.jpg" -"845" "Which section displays cells characterized by clear, vacuolated cytoplasm and variable nuclear size with some appearing hyperchromatic?" "Section B" "Section C" "Section A" "" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/845.jpg" -"846" "Based on the morphology and staining characteristics, which cellular component is least abundant in the image?" "Red blood cells" "Eosinophilic platelet-fibrin thrombi" "Eosinophilic extracellular material" "Nuclei of the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/846.jpg" -"847" "Based on the morphology observed in the tissue sample, what is the likely characteristic of the elongated structure indicated by the arrow?" "It displays a segmented body structure" "It has irregular nuclear pleomorphism" "It shows evidence of hyperchromatic nuclei" "It presents a uniform width throughout its length" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/847.jpg" -"848" "What feature of the stained tissue sample differentiates the round densely packed cells from the structure indicated by the arrow?" "The surrounding cells have a coiled morphology" "The surrounding cells are predominantly round and darkly stained" "The surrounding cells display elongated shapes" "The surrounding cells appear clear and unstained" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/848.jpg" -"849" "Analyzing the immunochemical stain pattern, which statement best describes the staining observed in the image?" "Intense nuclear staining in all cells indicating high mitotic activity" "Blue counterstain without evidence of specific immunostaining" "Light brown staining indicating CDX-2 positivity in some cells" "Uniform cytoplasmic staining without nuclear involvement in all cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/849.jpg" -"850" "What characteristic feature of the columnar epithelial cells lining the gastric glands can be seen in this H&E stained image?" "Multilayered nuclei arrangement" "Presence of cilia on the cell surface" "Basally located nuclei" "Apical nuclei location" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/850.jpg" -"851" "Based on what is typically visible in an H&E stain, which of the following cellular features of plasma cells is not discernible in this image?" "Clock-face chromatin pattern" "Perinuclear halo" "Nucleoli within the nuclei" "Eccentrically placed nucleus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/851.jpg" -"852" "What type of cellular morphology is predominantly observed in this microscopic view?" "Cuboidal cells with uniform nuclei" "Polygonal cells with centrally located nuclei" "Round cells with large nuclei" "Spindle-shaped cells with elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/852.jpg" -"853" "What is the predominant cellular morphology visible in this tissue section?" "Cuboidal cells arranged in duct-like structures" "Spindle-shaped cells arranged in fascicles" "Squamous cells forming stratified layers" "Columnar cells with apical mucin and basal nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/853.jpg" -"854" "How would you describe the staining characteristics of the nuclei in this microscopic view?" "Uniformly light-stained nuclei throughout the cells" "Binucleated cells with homogeneously stained nuclei" "Varied intensity of nuclear staining with some nuclei darker than others" "Nuclei with predominantly dark, condensed chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/854.jpg" -"855" "What type of extracellular matrix is evident surrounding the cells in this microscopic view?" "Calcified matrix with basophilic stippling" "Myxoid or mucoid substance" "Adipose tissue with prominent lipid vacuoles" "Dense and fibrous connective tissue matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/855.jpg" -"856" "What is the morphology of the leukocytes seen in the inset image?" "Smudge cells" "Monocytes with dendritic projections" "Hypersegmented neutrophils" "Hairy cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/856.jpg" -"857" "Given the connective tissue stroma visualized in this image, how would you characterize its appearance?" "Pale and amorphous with evenly distributed nuclei" "Green and reticular with organized structure" "Blue and fibrous with evenly dispersed nuclei" "Pink and fibrillary with disorganized arrangement" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/857.jpg" -"858" "What feature is predominantly indicated by the white arrows in the image?" "Necrotic muscle fibers" "Atrophic muscle fibers" "Hypertrophic muscle fibers" "Regenerating muscle fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/858.jpg" -"859" "Observing the muscle tissue architecture surrounding the area indicated by the black arrow, what pathological process can be inferred?" "Inflammatory cell infiltration" "Adipose tissue accumulation" "Muscle hypertrophy" "Fibrosis development" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/859.jpg" -"860" "Based on the staining characteristics, which cells likely represent erythrocyte precursors?" "Cells with prominent nucleoli and lobulated nuclei" "Cells with small, dense, darkly stained nuclei" "Cells with large nuclei and abundant cytoplasm" "Cells with pale cytoplasm and peripheral nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/860.jpg" -"861" "Based on the cellular morphology observed under H&E staining, what is a defining characteristic of the predominant cell population in this tissue sample?" "Pleomorphic nuclei with occasional prominent nucleoli" "Uniform cytoplasm with absence of intercellular variation" "Small, round nuclei with high nuclear-to-cytoplasmic ratio" "Monomorphic nuclei with small, barely visible nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/861.jpg" -"862" "What feature of the tissue stroma can be inferred from the microscopic examination of this image?" "Significant fibrosis throughout the stroma" "Presence of abundant myxoid matrix within the stroma" "Extensive necrosis intermingled with the stromal cells" "Homogenous stroma with interspersed cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/862.jpg" -"863" "What is the composition of the stroma surrounding the duct-like structures?" "Dense eosinophilic material without cellular components" "Acellular amorphous ground substance" "Myxoid stroma with interspersed spindle-shaped cells" "Collagen-rich dense connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/863.jpg" -"864" "In the central vessel, what best describes the content within the lumen?" "There are uniform, round, red structures within the lumen consistent with red blood cells" "The lumen contains a mixture of leukocytes and red blood cells" "There is the absence of cellular structures within the lumen" "Thrombotic material is present occluding the lumen" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/864.jpg" -"865" "Based on the size and morphology of the inclusions seen within some erythrocytes, what is the most likely identity of these inclusions?" "Heinz bodies" "Basophilic stippling" "Pappenheimer bodies" "Howell-Jolly bodies" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/865.jpg" -"866" "Based on the cytomorphologic features observed in the image, which hematologic malignancy is most consistent with the densely packed cells displaying scant cytoplasm and hyperchromatic nuclei?" "Acute lymphoblastic leukemia (ALL)" "Chronic myelogenous leukemia (CML)" "Chronic lymphocytic leukemia (CLL)" "Acute myeloid leukemia (AML)" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/866.jpg" -"867" "Considering the architectural effacement of the bone marrow by densely packed cells in the microscopic image, which feature is notably absent?" "Erythroid precursors" "Myeloid lineage cells" "Megakaryocytes" "Mitotic figures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/867.jpg" -"868" "What histopathological feature of the cells seen in the image indicates the aggressiveness of the disease process?" "The lack of significant nucleoli" "The small size and uniformity of the cells" "The irregular contours of some nuclei" "The coarse pattern of the chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/868.jpg" -"869" "The arrangement and morphology of the cells in this image are consistent with what type of tissue growth?" "Normal parenchyma" "An organized, well-delineated tumor" "Dysplastic tissue with severe pleomorphism" "Inflammatory infiltrate" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/869.jpg" -"870" "What is the predominant cytoplasmic staining characteristic of the cells in this tissue section?" "Basophilic (blue)" "Amphophilic (purple)" "Acidophilic (red)" "Eosinophilic (pink)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/870.jpg" -"871" "Analyzing the mitotic activity present in this tissue section, what does it suggest about the proliferation status of the cells?" "Reduced mitotic activity indicating slow proliferation" "High mitotic activity including abnormal mitotic figures" "Lack of mitotic figures suggesting cell cycle arrest" "Normal mitotic activity with typical mitotic figures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/871.jpg" -"872" "What characteristic feature of cellular morphology is predominantly observed in the given tissue section?" "Uniform cell size and shape" "Pleomorphism" "Monotonous nuclei" "Regular arrangement of cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/872.jpg" -"873" "Based on the cellular and tissue morphology, what does area A most likely represent?" "A well-preserved thyroid follicle with colloid" "A cavity or space within the tissue suggestive of a previous hemorrhagic event" "A lymphoid aggregate typically seen in chronic inflammation" "Squamous metaplasia common in chronic irritation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/873.jpg" -"874" "What does the lighter staining of the background tissue compared to the regions with cell concentration suggest about the composition of this tissue?" "Inflammation" "High cellularity" "Presence of fibrous connective tissue" "Abundance of extracellular matrix" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/874.jpg" -"875" "What histological feature is indicated by the yellow star?" "Epithelial cells forming a nest-like structure" "Striated muscle fibers" "Acinar cells" "Erythroid precursors" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/875.jpg" -"876" "Based on the area surrounding the cells labeled with stars, what is the characteristic of the connective tissue present?" "Dense irregular connective tissue with fibroblasts" "Collagen fibers and supportive stroma" "Myxoid stroma with loose extracellular matrix" "Hyaline cartilage with chondrocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/876.jpg" -"877" "Based on the appearance of the villi in the provided microscopic image of the small intestine, which of the following best describes the morphology of the villous epithelium?" "Squamous cells with centrally located nuclei" "Tall columnar cells with basally located nuclei" "Cuboidal cells with centrally located nuclei" "Tall columnar cells with apically located nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/877.jpg" -"878" "Identify the dilated structures highlighted by the arrows in the image. What is the most likely function of these structures within the small intestine?" "Fluid transport" "Gas exchange" "Waste excretion" "Nutrient absorption" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/878.jpg" -"879" "What histological feature can be identified by the presence of a cell with multiple nuclei?" "Apoptotic body" "Atypical mitotic figure" "Syncytiotrophoblast" "Multinucleated chondrocyte" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/879.jpg" -"880" "Based on the staining pattern, what type of stain is most prominent in this image?" "Giemsa stain" "Hematoxylin and eosin (H&E) stain" "Periodic acid–Schiff (PAS) stain" "Papanicolaou stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/880.jpg" -"881" "What term best describes the small, dark-staining, circular to oval spaces within the compact bone matrix?" "Canaliculi" "Lacunae" "Marrow cavities" "Haversian canals" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/881.jpg" -"882" "Based on the morphological features observed in the image, what type of cells predominantly indicate an inflammatory process?" "Cells with multiple nuclei forming a syncytium" "Cells with large cytoplasmic inclusions" "Cells with small, dark purple nuclei" "Cells with ample, foamy cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/882.jpg" -"883" "What feature characterizes the cell indicated by the arrowhead in the image?" "Hyperchromatic nuclei" "Prominent nucleoli" "Large, foamy cytoplasm" "Intracellular melanin pigment" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/883.jpg" -"884" "What describes the cell indicated by the arrow in the image?" "Cytoplasmic inclusions" "Single nucleus with surrounding halo" "Absence of a nucleus" "Multiple nuclei within a single enlarged cell body" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/884.jpg" -"885" "How would you describe the extracellular matrix in the tissue sample shown in the image?" "Edematous with abundant ground substance" "Eosinophilic and fibrous" "Necrotic with abundant neutrophil infiltration" "Myxoid with sparse collagen fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/885.jpg" -"886" "What is the most notable feature of the nuclei in the large prominent cells seen in the image?" "The nuclei are peripheral with a horseshoe shape." "The nuclei have a large, centrally-located, dark-staining appearance." "The nuclei show clear signs of segmentation into lobes." "The nuclei contain multiple, distinct nucleoli." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/886.jpg" -"887" "Based on the morphology observed in the image, which cellular adaptation is likely absent?" "Presence of cilia on the cell surface." "Presence of villi for increased surface area." "Presence of flagella for motility." "Presence of pseudopodia for amoeboid movement." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/887.jpg" -"888" "Considering the possible identity of the cells as a type of intracellular parasite, which characteristic might be expected but is not visible in the image?" "Clearly defined cell wall typical of fungal cells." "Schizont stage with merozoites visible inside the cell." "Trophozoite stage with evident food vacuoles." "Erythrocytic stages with ring formations typical of Plasmodium spp." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/888.jpg" -"889" "At ×200 magnification, what histopathological feature can be readily assessed in this image?" "Nucleoli detail" "Cytoplasmic granularity" "Nuclear pleomorphism" "CD20 expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/889.jpg" -"890" "What cellular abnormality can be primarily observed in this liver tissue?" "Presence of Mallory bodies" "Multinucleation of hepatocytes" "Lipid droplet accumulation" "Formation of fibrous septa" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/890.jpg" -"891" "What does the thick arrow in the glomerulus indicate?" "Entrapped red blood cell fragments" "Normal red blood cells" "Intracapillary hypercellularity" "Enlarged podocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/891.jpg" -"892" "What feature distinguishes the superficial layer of the epithelial cells in this image?" "Evidence of significant inflammatory infiltrate" "Loss of nuclei and cytoplasmic granularity" "Presence of large, prominent nuclei" "Regular spacing of spindle-shaped fibroblasts" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/892.jpg" -"893" "What can be inferred about the status of the basement membrane in this image?" "It is disrupted, allowing cellular infiltration" "It is smooth, indicating an intact boundary" "It shows significant pleomorphism and cellular atypia" "It is thickened with a high degree of collagen deposition" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/893.jpg" -"894" "Based on the microscopic examination of the glands present in the tissue, which descriptor best fits the architectural arrangement observed?" "Presence of a single layer of uniform cells" "Tubular structures with cells aligned in an organized fashion" "Regular, well-defined glandular structures" "Marked glandular crowding with little intervening stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/894.jpg" -"895" "What does the organization and polarity of the cells suggest about the tissue architecture?" "The cells are well-organized with clear polarity" "There is a disorganized tissue structure with a lack of cell polarity" "The cells are pseudostratified with maintained architecture" "The cytoplasm is abundant and cells exhibit normal polarity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/895.jpg" -"896" "What is the predominant staining characteristic of the nuclei in this image?" "Dark purple nuclei with irregular shapes" "Pale blue nuclei with uniform sizes" "Uniformly light purple nuclei with regular shapes" "Multinucleated giant cells with a clear halo" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/896.jpg" -"897" "What cellular feature indicated by white arrows suggests the presence of IgG4-positive plasma cells?" "The cells lacking a visible nucleus" "The presence of large, multi-nucleated cells" "The cells exhibiting a clear halo surrounding the nuclei" "The cells with cytoplasm enriched with a dark brown stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/897.jpg" -"898" "What is the staining characteristic of the cells with high nuclear-to-cytoplasmic ratios in this image?" "Eosinophilic cytoplasm with hyperchromatic nuclei" "Neutrophilic cytoplasm with smudged nuclei" "Amphophilic cytoplasm with nucleoli" "Basophilic cytoplasm with fine chromatin pattern nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/898.jpg" -"899" "Identify the likely nature of the fine granular material in the background of the smear." "Extracellular matrix components" "Precipitated staining artifact" "Necrotic cellular debris" "Mature erythrocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/899.jpg" -"900" "What does the blue arrow in the image signify within the tissue section?" "Sebaceous gland" "Nerve bundle" "Lymphatic vessel" "Melanocyte" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/900.jpg" -"901" "What can be inferred about the cell that is marked with an arrowhead?" "It exhibits nucleomegaly" "It is smaller than the surrounding cells" "It shows features characteristic of cell death" "It is undergoing mitosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/901.jpg" -"902" "How does the staining pattern of the extracellular space contribute to the analysis of this tissue?" "It highlights the extracellular matrix composition" "It indicates a high concentration of extracellular enzymes" "It signifies the presence of dense connective tissue" "It helps in delineating the cell boundaries clearly" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/902.jpg" -"903" "Which cellular feature primarily observed in these lymphocytes suggests a neoplastic process rather than a reactive condition?" "Diverse cellular sizes and shapes indicating pleomorphism" "Prominent nucleoli within the cells" "High nuclear-to-cytoplasmic ratio" "Significant cytoplasmic volume in most cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/903.jpg" -"904" "What feature can be observed in the stratum corneum of this skin section?" "Retained nuclei in cells that should typically be anucleate" "Prominent granular layer with keratohyalin granules" "Uniform cell size and shape without nuclei" "Presence of keratin with anucleate squamous cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/904.jpg" -"905" "What type of morphological characteristic is evident in the cells within the observed tissue section?" "Signet ring cell morphology with prominent cytoplasmic vacuoles" "Epithelioid cell morphology with ample cytoplasm" "Spindle cell morphology with elongated nuclei" "Round cell morphology with high nucleus-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/905.jpg" -"906" "What histopathological feature is indicated by the noticeably thickened layer observed in the uppermost region of this skin tissue section?" "Acantholysis" "Hyperkeratosis" "Papillomatosis" "Acanthosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/906.jpg" -"907" "Based on the overall morphology and visible epidermal changes, what pathological condition does this skin tissue section likely represent?" "Pemphigus vulgaris" "Psoriasis" "Lichen planus" "Necrolytic migratory erythema" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/907.jpg" -"908" "What aspect of this image is indicative of a high proliferative index within the tumorous cells?" "Regularly arranged mitotic spindles" "The presence of cells with scant cytoplasm" "Large intercellular spaces separating the cells" "The presence of cells with abundant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/908.jpg" -"909" "Considering the visible cellular features, what type of nuclear alteration is predominantly observed in the specimen?" "Hyperchromasia" "Vesicular nuclei with prominent nucleoli" "Nuclear molding" "Multinucleation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/909.jpg" -"910" "What arrangement of the cells can be observed in the histologic image provided?" "Small acinar structures" "Indian file pattern" "Palisading" "Syncytial arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/910.jpg" -"911" "What tissue staining method has likely been used in this microscopic image?" "Giemsa" "Periodic acid-Schiff" "Hematoxylin and eosin" "Masson's trichrome" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/911.jpg" -"912" "What can be deduced about the cellularity of the glomerulus in this image?" "There is decreased cellularity within the glomerulus" "There is a prominent increase in podocyte number" "There is significant proliferation of endothelial cells" "The cellularity of the glomerulus is within normal limits" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/912.jpg" -"913" "What is the appearance of the nuclei in the observed cells?" "Presence of multiple nucleoli in each nucleus" "Markedly pleomorphic with irregular borders" "Deeply basophilic with high nuclear-to-cytoplasmic ratio" "Round to oval with uniform shape" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/913.jpg" -"914" "How would you characterize the chromatin pattern of the cell nuclei?" "Dense chromatin with marginated distribution" "Hyperchromatic with coarse clumping" "Nuclei with predominantly open chromatin giving a lighter appearance" "Varied chromatin patterns with areas of clearing" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/914.jpg" -"915" "Based on the cellular morphology, what type of tissue proliferation is suggested by the histologic features observed in this high-power field?" "Benign cartilaginous proliferation" "Malignant neoplastic hematopoietic infiltration" "Benign adipose tissue hyperplasia" "Malignant osteoid formation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/915.jpg" -"916" "Within the context of the stained cerebral tissue, what can be inferred about the regions with pink-staining fibrillary structures?" "They represent normal vascular structures within the tissue" "They correspond to areas of demyelination" "They are consistent with neuropil" "They indicate the presence of robust angiogenesis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/916.jpg" -"917" "Considering the cellular characteristics visible in the image, which aspect does NOT feature prominently in the morphology of these cells?" "Cigar-shaped nuclei" "Eosinophilic cytoplasm" "Cellularity that appears excessive" "Nuclei exhibiting uniformity in size and staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/917.jpg" -"918" "What is the nature of the inflammatory infiltrate surrounding the polypoid granulation tissue structures?" "Predominantly eosinophils" "Predominantly macrophages" "Predominantly neutrophils" "Predominantly lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/918.jpg" -"919" "Based on the arrangement of the chondrocytes in the microscopic image, what is the most likely location from which this tissue sample was obtained?" "Fibrocartilaginous intervertebral disc" "Articular cartilage of a synovial joint" "Elastic cartilage of the ear" "Growth plate of a long bone" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/919.jpg" -"920" "How does the nuclear variability and cellularity within the alveolar septae affect the differential diagnosis?" "Represents interstitial inflammation" "Indicates a benign reactive process" "Suggests neoplastic transformation" "Signifies normal aging changes " "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/920.jpg" -"921" "Which cellular component is predominantly targeted by the dark brown stain used in this histological section?" "Extracellular matrix" "Cytoplasm" "Cell membranes" "Nucleoli or nuclear organizer regions" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/921.jpg" -"922" "Based on the appearance of the stratum corneum in this H&E stained skin tissue section, what does the retention of nuclei within this layer indicate?" "Hypergranulosis" "Parakeratosis" "Acantholysis" "Orthokeratosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/922.jpg" -"923" "Analyzing the pattern of the epidermis in this H&E stained skin tissue section, what observation is made about the rete ridges?" "Hyperplasia of rete ridges" "Effacement of rete ridges" "Presence of elongated rete ridges" "Presence of shortened rete ridges" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/923.jpg" -"924" "In the dermal region of this H&E stained skin tissue section, what pathological feature can be observed?" "RBC extravasation" "Increased melanin deposition" "Vasculitis" "Neutrophilic infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/924.jpg" -"925" "Based on the histological features observed, what is the predominant type of inflammatory cell infiltrate?" "Lymphocytes" "Eosinophils" "Neutrophils" "Macrophages" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/925.jpg" -"926" "Regarding the nuclei of these cells, which of the following descriptions matches the nuclear chromatin pattern observed in the sample?" "Dispersed and stippled" "Hypochromatic and condensed" "Hyperchromatic and clumped" "Pyknotic and fragmented" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/926.jpg" -"927" "What can be inferred about the level of mitotic activity in this tissue sample?" "Low mitotic activity with few mitotic figures" "Mitotic figures absent indicating quiescence" "High mitotic activity with numerous mitotic figures" "Irregular mitotic figures suggesting apoptosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/927.jpg" -"928" "From the morphology of the cells, what can be inferred about the proliferative activity of the cells shown?" "The cells possess uniform nuclear features, indicative of a low proliferative index" "The cells show substantial variation in nuclear size, suggesting a high proliferative index" "There is evidence of high mitotic activity" "The cells are predominantly in a quiescent state" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/928.jpg" -"929" "Are there any morphological signs of apoptosis in the cells provided in the image?" "No, the image does not show any visual evidence of apoptosis" "Yes, there are visible features of chromatin condensation" "Yes, there are overt signs of cell shrinkage" "No, the image shows signs of necrosis instead of apoptosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/929.jpg" -"930" "What type of cellular morphology is indicated by the elongated structures within the dermal layer that are labeled with a black arrow in the image?" "Adipose cells." "Melanocytes." "Endothelial cells." "Squamous epithelial cells." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/930.jpg" -"931" "Evaluating the cellular features, which statement accurately reflects the nuclear characteristics of the cells lining the glands?" "Small nuclei with inconspicuous nucleoli" "Uniform nuclei with sparse chromatin" "Regular nuclear size and shape with clear nuclear membranes" "Nuclear pleomorphism with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/931.jpg" -"932" "In this microscopic image of adipose tissue, which statement accurately characterizes the visibility of the nuclei within the adipocytes?" "Nuclei are multiple within each adipocyte" "Nuclei are not clearly visible in each adipocyte" "Nuclei are centrally located within the adipocytes" "Nuclei are prominently visible at the periphery of each adipocyte" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/932.jpg" -"933" "Analyzing the spindle-shaped cells' arrangement in the stromal matrix, which pattern describes their organization?" "Disorganized and randomly distributed" "Rosette formation around a central space" "Palisading at the periphery of the tissue" "Highly organized and uniform" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/933.jpg" -"934" "In the given histology slide, what is the likely composition of the background matrix in which the spindle cells are embedded?" "Dense irregular connective tissue" "Collagenous tissue" "Adipose tissue" "Loose connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/934.jpg" -"935" "In the top layer of the tissue, what does the structure and arrangement of the flattened cells indicate?" "They represent simple squamous epithelium" "They represent transitional epithelium" "They suggest columnar epithelial cells" "They indicate a layer of stratified squamous epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/935.jpg" -"936" "Based on the observed histological features, which area shows the most severe hepatocyte damage?" "Area labeled '1'" "Areas farthest from any vein" "Area labeled '2'" "Area adjacent to the PV" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/936.jpg" -"937" "What type of cells predominates the microscopic landscape in this image?" "Squamous cells" "Adipocytes" "Epithelial cells" "Spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/937.jpg" -"938" "Based on the cellular morphology, what is the most likely process occurring within this tissue?" "Neoplastic transformation" "Acute inflammation" "Chronic inflammation" "Regeneration process" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/938.jpg" -"939" "What is the predominant pattern of the glandular structures observed in this tissue?" "Circular with uniform cell distribution" "Well-defined with regular borders" "Tubular with polarized nuclei" "Irregularly shaped with infiltrative growth" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/939.jpg" -"940" "The nuclei of the cells lining the glandular structures show which of the following features?" "Single prominent nucleolus and anisonucleosis" "Pleomorphism and hyperchromasia" "Bi-nucleation with prominent cytoplasm" "Uniformity and hypochromasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/940.jpg" -"941" "What is the composition of the crescent-shaped structure observed within Bowman's capsule?" "Numerous cells that are closely packed together with scant cytoplasm." "Organized layers of squamous epithelial cells." "Primarily adipocytes with large lipid vacuoles." "Dense connective tissue with extensive collagen fibers." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/941.jpg" -"942" "Analyzing the dermis layer beneath the epidermis, what notable feature is missing from this field of view?" "Lymphocytic infiltration indicative of an immune response" "Collagen fibers forming the extracellular matrix" "Keratinocyte arrangement characteristic of the epidermis" "Fibroblasts responsible for extracellular matrix production" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/942.jpg" -"943" "Looking at the histopathological image, what can be inferred about the arrangement of the basal cells?" "The nuclei are randomly organized without a palisaded arrangement" "The nuclei exhibit atypical mitotic figures" "The nuclei form a dense and hyperchromatic layer" "The nuclei are lined up in a regular, palisaded row" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/943.jpg" -"944" "What feature of the epithelial surface is most consistent with the description of the topmost layer?" "The epithelial surface has cells with centrally located nuclei." "The epithelial surface has cells with apically located nuclei." "The epithelial surface has cells with no discernible nuclei." "The epithelial surface has cells with basally located nuclei." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/944.jpg" -"945" "What does the intense brown cytoplasmic staining in the cells beneath the epithelial layer most likely indicate?" "Melanin accumulation within the cells" "S100 protein positivity in the cells" "Glycogen presence in the cells" "Lipid accumulation within the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/945.jpg" -"946" "What does the thick arrow in the image likely indicate?" "Accumulation of adipocytes" "Dense inflammatory infiltrate" "Areas of hemorrhage" "Evidence of bone debris" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/946.jpg" -"947" "Identify the morphological feature indicated by the dashed arrow in the image." "Keratin pearls" "Calcific deposits" "Mucinous secretion" "Lipid vacuoles" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/947.jpg" -"948" "What does the pink background staining indicate about the quality of the Papanicolaou stain in this microscopic image?" "Insufficient fixation of the tissue" "Presence of bacterial contamination" "Adequate differentiation between cytoplasmic components" "Overstaining of the cellular components" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/948.jpg" -"949" "Considering the absence of malignant features, what can be inferred from the uniformity of the cell nuclei observed in the image?" "Presence of necrosis" "Benign inflammatory process" "Advanced stage of cell differentiation" "High mitotic index" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/949.jpg" -"950" "Based on the staining pattern observed, how would you describe the expression of the antigen within these cells?" "Centrally concentrated but sparse" "Peripheral and focal" "Heterogeneous and weak" "Homogeneous and strong" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/950.jpg" -"951" "Based on the organization of the more densely stained cells in this microscopic view, what could these cells most likely represent?" "Cardiac myocytes" "Renal tubular cells" "Squamous epithelial cells" "Hepatocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/951.jpg" -"952" "What is the staining characteristic observed in the cytoplasm of the more densely stained elongated cells, indicative of potential degenerative changes?" "Homogeneously dark staining" "Variation in staining intensity" "Multiple, distinct vacuoles" "Consistent eosinophilic staining throughout" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/952.jpg" -"953" "Based on the immunohistochemical staining pattern observed, what is the most likely localization of the targeted antigen?" "Nuclear" "Extracellular matrix" "Membranous" "Cytoplasmic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/953.jpg" -"954" "What does the uniformity of the brown staining suggest about the process occurring within the cells?" "Polyclonal hyperplasia" "Monoclonal proliferation" "Granulomatous inflammation" "Acute inflammation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/954.jpg" -"955" "Examining the variation in size and nuclear-to-cytoplasmic ratios of the cells, what can be inferred about their appearance?" "Anaplastic" "Monomorphic" "Pleomorphic" "Hyperchromatic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/955.jpg" -"956" "What is the predominant shape of the cells in this high-power field view of the tissue sample?" "Columnar" "Round" "Cuboidal" "Spindle-shaped" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/956.jpg" -"957" "How can we describe the appearance of the nuclei within these cells?" "Hyperchromatic and round" "Pleomorphic and hyperchromatic" "Small and round with prominent nucleoli" "Elongated matching spindle shape of cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/957.jpg" -"958" "What is the predominant cellular arrangement seen in this tissue section?" "Hyaline cartilage" "Stratified squamous epithelium" "Simple columnar epithelium" "Loose connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/958.jpg" -"959" "What characteristic of the nuclei in this tissue sample could suggest active cellular processes?" "Variation in nuclear size" "Centrally located nucleoli" "Uniform staining intensity" "Presence of nuclear inclusions" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/959.jpg" -"960" "Based on the image, what is an observation about the epithelial tissue integrity?" "Dense inflammatory infiltrate" "Maintenance of glandular architecture" "Loss of cellular cohesion" "Uniform basolateral compartment" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/960.jpg" -"961" "The cells with small, round nuclei found within the fibrotic regions are suggestive of what cell type?" "Lymphocytes" "Fibroblasts" "Hepatocytes" "Endothelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/961.jpg" -"962" "What type of cellular structure is predominantly marked with blue arrows in the microscopic view of the lung tissue?" "Lymphocytes" "Neutrophils" "Erythrocytes" "Macrophages" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/962.jpg" -"963" "What is the predominant hue of the extracellular matrix observed in this lung tissue sample?" "Orange to brown" "Green to yellow" "Dark blue to purple" "Pink to red" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/963.jpg" -"964" "What is the appearance of the hepatocyte cytoplasm in this liver tissue section?" "Eosinophilic (pink) without significant granular appearance" "Vacuolated with large clear spaces" "Predominantly basophilic (blue) throughout the tissue" "Eosinophilic (pink) with sporadic brownish granular pigmentation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/964.jpg" -"965" "Which of the following describes the interstitial changes observed in this image?" "Increased number of inflammatory cells" "Widespread necrosis" "Presence of numerous lipid droplets" "Decreased cellularity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/965.jpg" -"966" "In the given tissue section, what is the nature of the keratinization observed?" "Presence of individual cell keratinization" "Keratinization with a clear granular layer" "Complete absence of keratinization" "Presence of squamous pearls indicative of keratinization" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/966.jpg" -"967" "Considering the morphology of the smaller cell population in this image, how would you describe the nuclei?" "The nuclei are hypertrophic and deeply eosinophilic" "The nuclei are hyperchromatic with relatively consistent sizing" "The nuclei are hyperchromatic and vary in size" "The nuclei are uniform with a pale appearance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/967.jpg" -"968" "What is the architectural pattern of the tissue based on the spatial arrangement of the larger keratinizing cells relative to the smaller spindled and epithelioid cells?" "Mostly differentiated with occasional admixture of cells" "Poorly differentiated with an admixed arrangement of cells" "Well-differentiated with clear demarcation between cell types" "Anaplastic with no recognizable structures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/968.jpg" -"969" "Considering the cytoplasm to nucleus size ratio, how would you categorize the majority of the observed cells?" "Cells have a moderate cytoplasm to nucleus size ratio" "Cells have a high cytoplasm to nucleus size ratio" "Cells with almost equal cytoplasm and nucleus sizes" "Cells exhibit a small cytoplasm to nucleus size ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/969.jpg" -"970" "How would you describe the nuclear characteristics of the cells in the islets, as seen in the microscopic image?" "Small, hyperchromatic nuclei with inconspicuous nucleoli" "Varied nuclear sizes with coarse chromatin" "Uniform nuclei with fine chromatin" "Uniform nuclei with condensed chromatin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/970.jpg" -"971" "What is the predominant cytoplasmic staining characteristic of the larger cells within the islets?" "Eosinophilic (pink) cytoplasm" "Amphophilic (purple) cytoplasm" "Basophilic (blue) cytoplasm" "Clear, vacuolated cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/971.jpg" -"972" "What is the morphology of the suspected fungal hyphae observed in the tissue sample?" "Rod-shaped and singular" "Filamentous with septations" "Short and coccoid" "Tubular and branching" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/972.jpg" -"973" "Within the image, there are rounded bodies that suggest a specific reproductive structure in fungi. What are these structures most likely to be?" "Conidia within a conidiophore" "Spores within a sporangium" "Ascospores within an ascus" "Basidia within a basidiocarp" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/973.jpg" -"974" "Based on the cellular features visualized, which type of infection do the observed tissue and cell morphologies most likely indicate?" "Parasitic infection" "Viral infection" "Bacterial infection" "Fungal infection" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/974.jpg" -"975" "What type of staining can be observed at the foci indicated by the red arrows in the glandular structures?" "Alcian blue" "Hematoxylin and eosin" "Immunohistochemical" "Periodic acid-Schiff" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/975.jpg" -"976" "What is the defining characteristic of the giant cells observed in this histological section?" "Large size with a single central nucleus" "Multiple centrally located nuclei" "Presence of a large nucleus taking up most of the cell body" "Large size with multiple peripheral nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/976.jpg" -"977" "Based on the morphology, what type of cell predominates in this tissue section?" "Spindle-shaped cells with elongated nuclei" "Columnar cells with basal nuclei" "Cuboidal cells with central nuclei" "Round cells with abundant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/977.jpg" -"978" "In the context of the pathology shown, how does the extracellular matrix appear?" "Calcified with absence of cells" "Osteoid in composition" "Hyalinized and acellular" "Myxoid with scattered spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/978.jpg" -"979" "Based on the characteristics of the nuclei in the glomerulus, what is the most likely appearance of the podocytes and other cells within the glomerulus?" "The nuclei are pink to purple with lighter cytoplasm" "The nuclei are swollen with a foamy cytoplasm" "The nuclei are fragmented, suggesting karyorrhexis" "The nuclei are hyperchromatic with high nuclear-to-cytoplasmic ratios" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/979.jpg" -"980" "Considering the morphology of the tissue pointed out by the yellow arrow, what characteristic feature is observable that indicates a mesenchymal origin of malignancy?" "Glandular formation" "Organized arrangement" "Round nuclei" "Eosinophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/980.jpg" -"981" "Based on the cellular arrangement and nuclear staining pattern seen in the outermost layer, which of the following descriptions best characterizes the epithelial morphology?" "The nuclei are enlarged with variations in size and shape, accompanied by abundant eosinophilic cytoplasm." "The nuclei are hyperchromatic with prominent nucleoli and exhibit high staining intensity." "The nuclei appear small and uniform with sparse cytoplasmic presence." "The nuclei are arranged in a linear, orderly fashion without any overlapping or crowding." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/981.jpg" -"982" "Considering the features observed in the stromal component beneath the epithelial layer, which of the following best represents the tissue response?" "A minimal inflammatory infiltrate, evidenced by sparse cell density and lack of intensely staining inflammatory cells." "A dense fibrous connective tissue with abundant collagen fibers." "A robust inflammatory infiltrate, with a high density of polymorphonucleocytes." "A high level of angiogenesis with numerous newly formed blood vessels." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/982.jpg" -"983" "In the underlying connective tissue observed in the image, what best characterizes the cells with large, round nuclei?" "They are erythrocytes lacking a nucleus" "They are lymphocytes with a high nucleo-cytoplasmic ratio" "They are fibroblasts with ample cytoplasm and a large nucleus" "They are neutrophils exhibiting multi-lobed nucleus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/983.jpg" -"984" "What is the predominant microscopic feature of the bone marrow tissue in this image?" "Presence of megakaryocytes" "Homogeneous distribution of hematopoietic cells" "Dense network of coarse black fibers" "Abundance of erythroid precursors" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/984.jpg" -"985" "How does the background matrix of the bone marrow tissue appear in this image?" "Showing significant lymphocytic infiltration" "Largely filled with myeloid precursors" "Exhibiting large areas of hemorrhage" "Dominated by a prominent network of reticulin fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/985.jpg" -"986" "How would you describe the appearance of the eosinophilic cytoplasm present in this tissue sample?" "Elongated and moderately stained" "Sparse and faintly stained" "Homogeneous and darkly stained" "Granular and opaque" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/986.jpg" -"987" "Which characteristic pattern is observed in the arrangement of the spindle-shaped cells in this microscopic image?" "Storiform pattern" "Glandular formation" "Palisading arrangement" "Rosette formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/987.jpg" -"988" "Considering the morphology of the cells observed under microscopy, which feature is NOT evident in the field of view of the image?" "Significant pleomorphism" "Moderate amount of cytoplasm" "Elongated nuclei with visible nucleoli" "Uniform distribution of cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/988.jpg" -"989" "Assessing the tissue's stromal background, which of the following observations is NOT supported by the image?" "Variably eosinophilic stroma" "Herringbone appearance" "Collagenized stroma" "Abundant inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/989.jpg" -"990" "In the microscopic view of the renal tissue, what do the tubular structures primarily indicate?" "Acute tubular necrosis" "Normal tubular morphology" "Tubular atrophy" "Microcystic dilatation of tubules" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/990.jpg" -"991" "Considering the surrounding interstitial tissue in the renal biopsy sample, which of the following best matches the observations?" "Indications of severe interstitial edema" "No significant pathological alterations visible" "Presence of significant inflammatory infiltrate" "Evidence of extensive interstitial fibrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/991.jpg" -"992" "In the stroma surrounding the clusters, what is the characteristic of the connective tissue that can be observed?" "Highly cellular with many inflammatory cells." "Dense with abundant extracellular matrix." "Necrotic with evidence of tissue breakdown." "Less cellular with sparse stromal cells." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/992.jpg" -"993" "Based on the cellular morphology, which phase best describes the central cells observed in the follicle-like structures?" "Primary growth phase" "Atretic phase" "Tertiary growth phase" "Secondary growth phase" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/993.jpg" -"994" "Which type of cellular organization is evident in the tissue architecture outside of the follicle-like structures?" "Adipose clusters" "Acinar formations" "Isotropic arrangement" "Lamellar-like formations" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/994.jpg" -"995" "What type of epithelium is displayed on the surface of this tissue section?" "Columnar epithelium" "Transitional epithelium" "Squamous epithelium" "Cuboidal epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/995.jpg" -"996" "Based on the microscopic image, what is the likely function of the cells in the uppermost epithelial layer?" "Absorption" "Hormone secretion" "Keratin production" "Mucus secretion" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/996.jpg" -"997" "What feature is characteristic of the cells within the nodular collections seen in the tissue?" "Hyperchromatic spindle-shaped nuclei" "Multinucleation with prominent nucleoli" "Abundant cytoplasm with a foamy appearance" "Intracytoplasmic neutrophilic inclusions" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/997.jpg" -"998" "What does the eosinophilic matrix in the microscopic image suggest regarding the extracellular matrix components?" "Abundant myxoid material" "High glycosaminoglycan content" "Extensive necrosis" "Dense collagenous stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/998.jpg" -"999" "What is the significance of the brown staining observed in the cells?" "It reveals areas of calcification within the tissue" "It is a non-specific background staining" "It shows positivity for a specific antigen such as CK20" "It indicates necrotic cell death" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/999.jpg" -"1000" "What can be inferred about the homogeneity of the tumor cells based on the image?" "Irregular sizes and shapes suggest heterogeneity" "The cells have uniform shapes and sizes promoting the idea of homogeneity" "The uniform staining pattern suggests homogeneity" "The presence of numerous mitotic figures suggests homogeneity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1000.jpg" -"1001" "What can be inferred about the areas that stain darker within the bone matrix?" "They are indicative of bone marrow infiltration" "They suggest areas of calcification" "They are spaces housing osteocytes" "They represent increased blood supply" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1001.jpg" -"1002" "What is the arrangement of the nuclei in the multinucleated giant cell indicated by the red arrow?" "Horseshoe pattern" "Circle arrangement" "Random scattering" "Single linear arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1002.jpg" -"1003" "What is the characteristic staining pattern of the extracellular matrix components around the cells?" "Purple with speckles" "Greenish-yellow" "Dark blue" "Light pink" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1003.jpg" -"1004" "Based on the glandular structures observed, which feature best describes the organization of the nuclei within the cells lining the glands?" "Hyperchromatic nuclei with stratification" "Monolayered nuclei with regular spacing" "Euchromatic nuclei with organized polarity" "Isomorphic nuclei with uniform size" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1004.jpg" -"1005" "The tissue morphology in the image suggests a certain type of growth pattern. What type of growth pattern is observed in the glandular structures?" "Squamous differentiation" "Papillary configuration" "Whorled arrangement" "Tubular formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1005.jpg" -"1006" "Analyzing the epidermal thickness in the histological section, which description is most accurate?" "Normal epidermal thickness with uniform keratinocyte arrangement" "Thinning of the epidermis indicative of atrophy" "Acanthosis with significant rete ridge elongation" "Hyperkeratosis and parakeratosis are apparent" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1006.jpg" -"1007" "What can be inferred about the E-cadherin staining from the micrograph?" "There is strong E-cadherin staining outlining cell borders" "E-cadherin staining is homogenous across the tissue" "E-cadherin staining is present in all nuclei" "The image shows a lack of E-cadherin staining indicating reduced cell adhesion" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1007.jpg" -"1008" "What morphological feature is NOT evident in the nuclei of the squamous epithelium?" "Hyperchromasia" "Centrally-placed location" "Multilobation" "Pleomorphism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1008.jpg" -"1009" "What can be inferred about the nuclear morphology of these cells?" "The nuclei are highly pleomorphic" "The nuclei are large and vesicular" "The nuclei are not clearly defined" "The nuclei show multiple nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1009.jpg" -"1010" "What is the cellular arrangement seen in the image?" "Cells are organised in a glandular pattern" "A common cytoplasmic background in multinucleated cells suggests aggregation" "The cells are aligned in a pseudo-stratified columnar form" "There is significant cellular overlap" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1010.jpg" -"1011" "What feature is indicated by the cell with the black arrow in the image?" "Evidence of erythrophagocytosis indicated by the internal structure" "Presence of multiple nuclei suggesting a syncytial arrangement" "Cytoplasmic vacuolation signifying an advanced degenerative state" "Clear evidence of karyorrhexis indicating ongoing apoptosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1011.jpg" -"1012" "What can be inferred about the cell denoted by the black arrowhead in this image?" "This cell exhibits characteristics of acute inflammatory response" "It has features of a megakaryocyte with abundant cytoplasm" "The cell represents a cyst form with a rounded border" "It shows signs of active mitosis with visible spindles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1012.jpg" -"1013" "Which feature characterizes the cells indicated by the yellow arrow?" "Regularity in the shape and size of the nuclei" "Uniform nuclear chromatin without visible clumping" "An irregularly shaped nucleus with variations in chromatin density" "The presence of a well-defined nucleolus within the nucleus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1013.jpg" -"1014" "Based on the image, what is the primary morphological abnormality observed within the glomerulus?" "Presence of numerous crescents" "Advanced glomerulosclerosis" "Significant increase in cellularity" "Extensive fibrosis and scarring" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1014.jpg" -"1015" "Given the cellular morphology visible in the image, which of the following is least likely to be associated with the observed histopathological changes?" "Minimal change disease" "Diabetic glomerulosclerosis" "Acute post-infectious glomerulonephritis" "Membranoproliferative glomerulonephritis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1015.jpg" -"1016" "In the histological section provided, what morphology is displayed by the structures labeled with black arrows?" "Round acinar structures" "Dispersed neuroglial cells" "Irregular connective tissue fibers" "Elongated endothelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1016.jpg" -"1017" "Based on the staining characteristics, which antigen is most likely targeted by the immunohistochemical stain in this sample?" "CD20 typically found on B-cells" "CD34 associated with endothelial cells" "GFAP specific to astrocytes" "CD3 typically found on T-cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1017.jpg" -"1018" "By examining the microscopic features in the image, identify the predominant staining characteristic of the cytoplasm of the majority of cells within this lymph node tissue." "Neutrophilic (neutral)" "Amphophilic (purple)" "Basophilic (blue)" "Eosinophilic (pink)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1018.jpg" -"1019" "Focusing on the nuclear characteristics, what observation is prevalent among the cells in this lymph node biopsy?" "Most nuclei appear fine to moderately clumped" "Most nuclei exhibit excessive pleomorphism" "Most nuclei are small and hyperchromatic" "Most nuclei are large with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1019.jpg" -"1020" "What is the tissue architecture within the lymph node biopsy?" "Well-defined nodular structures with germinal centers" "High density of cellular infiltrate with interspersed stroma" "Extensive fibrosis with thick collagen bands" "Uniform sheets of monomorphic cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1020.jpg" -"1021" "Based on the pattern of brown staining seen in the image, which cellular component is most likely being targeted by the immunostaining technique?" "Cell surface receptors" "Cytoplasmic proteins" "Extracellular matrix components" "Nuclear material" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1021.jpg" -"1022" "Which staining technique is most likely used based on the distinct blue coloration of the tubular structure's perimeter?" "Masson's trichrome" "Periodic acid-Schiff (PAS)" "Hematoxylin and eosin (H&E)" "Wright's stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1022.jpg" -"1023" "Based on the microscopic features, what histopathological feature can be identified in the image?" "Parakeratosis" "Psoriasiform hyperplasia" "Spongiosis" "Acanthosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1023.jpg" -"1024" "What does the presence of hyperchromatic nuclei in the epidermis signify?" "An inflammatory reaction" "An infiltrative process" "Normal cell maturation" "Keratinocyte hyperplasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1024.jpg" -"1025" "What is the predominant cytoplasmic staining characteristic of the cells viewed in this image?" "Amphophilic" "Neutrophilic" "Basophilic" "Eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1025.jpg" -"1026" "In the provided image, what is the state of the stratum granulosum just below the cornoid lamella?" "Complete absence of the stratum granulosum" "Hypogranulosis with a visibly diminished layer of keratohyalin granules" "Normal granular layer with typical keratohyalin distribution" "Hypergranulosis with overly abundant keratohyalin granules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1026.jpg" -"1027" "How would you characterize the nuclei of the epithelial cells observed in the glands?" "Vesicular with prominent nucleoli" "Multinucleated giant cells" "Pyknotic" "Hyperchromatic and crowded" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1027.jpg" -"1028" "Considering the absence of staining in the section, what is the potential limitation when assessing the tissue for pathological changes?" "Identifying the type of epithelial cells" "Assessing the glandular architecture" "Evaluating cellular or nuclear atypia" "Determining the presence of mucinous substance in the stroma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1028.jpg" -"1029" "Which of the following options best describes the cells likely representing hematopoietic activity based on their morphological features in the image?" "Small cells with scant cytoplasm and dense nuclear staining" "Large cells with spacious cytoplasm and multiple nuclei" "Cells with elongated shapes and dense, violet staining" "Round cells with a high degree of uniformity and dense staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1029.jpg" -"1030" "What cellular morphology is predominantly seen in the provided microscopic image of this tissue sample?" "Spindle-shaped cells with a disorganized architecture" "Squamous cells with keratin pearl formation" "Columnar cells with regular crypt formations" "Cuboidal cells with organized acinar structures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1030.jpg" -"1031" "Based on the microscopic characteristics observed in the image, what type of remodeling is evident in the bronchial mucosa?" "Squamous metaplasia" "Goblet cell hyperplasia" "Fibrotic remodeling" "Mucous gland hypertrophy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1031.jpg" -"1032" "In section A of the image, which cell type is predominantly altered due to an abnormal proliferation?" "Kupffer cells" "Plasma cells" "Hepatocytes" "Endothelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1032.jpg" -"1033" "What structural feature is indicated by the arrows in the image?" "Osteoporotic trabeculae" "Haversian canals" "Sharpey's fibers" "Cementum annuli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1033.jpg" -"1034" "If one were to estimate the age of the subject from which this sample was taken, what feature should be focused upon?" "Concentric layers surrounding elongated structures" "Gaps or voids within the matrix" "Dark elongated vascular channels" "Parallel lines indicated by arrows" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1034.jpg" -"1035" "Based on the staining characteristics observed, what is the predominant cellular organelle visible in the cytoplasm of cells labeled '1'?" "Mitochondria" "Endoplasmic reticulum" "Lysosomes" "Golgi apparatus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1035.jpg" -"1036" "Assessing the morphology of the cells at label '2', what type of vessel is most likely featured in this histological section?" "Capillary" "Artery" "Lymphatic vessel" "Vein" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1036.jpg" -"1037" "When examining the nuclei of the hepatocytes labeled '1', what can be deduced about the cellular state?" "The nuclei are hyperchromatic, suggesting increased DNA content and possible aneuploidy" "The nuclei are centrally located and uniform, indicative of normal hepatocyte architecture" "The nuclei exhibit multiple nucleoli, which is often seen in metabolically active cells" "The nuclei are pleomorphic, indicating high variability and potential malignancy" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1037.jpg" -"1038" "In the given histological section of the pituitary gland, what type of cells are indicated by the solid arrows noted for their eosinophilic staining properties?" "Acidophils" "Folliculostellate cells" "Chromophobes" "Basophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1038.jpg" -"1039" "Identify the entities demarcated by the asterisks (*) within the glandular microenvironment in the image." "Blood capillaries" "Acidophils" "Neurons" "Collagen fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1039.jpg" -"1040" "Based on the image, which description best fits the appearance and potential condition of the epithelium?" "The epithelium presents multiple cell layers with an attached layer of basal cells" "The epithelium comprises multiple cell layers with a disorganized basal cell layer" "The epithelium has a single layer of cells and a continuous, regular basement membrane" "The epithelium is characterized by a consistent thickness across the section" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1040.jpg" -"1041" "What is the predominant chromatin pattern observed in the nuclei of cells within this image?" "Finely dispersed chromatin" "Uniformly condensed chromatin" "Variably dispersed to condensed chromatin" "Absence of visible chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1041.jpg" -"1042" "In the submucosa (SM), what is the likely identity of the round to oval structures with darker staining and clear lumens?" "Lymphatic vessels" "Neural ganglia" "Skeletal muscle fibers" "Blood vessels" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1042.jpg" -"1043" "Which layer in this histological section of the esophagus is characterized by connective tissue with fibers distributed in various directions and contains tubular glands?" "Lamina propria (LP)" "Submucosa (SM)" "Inner circular muscle (CM)" "Outer longitudinal muscle (LM)" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1043.jpg" -"1044" "What type of nuclear atypia can be observed in this histological image?" "Enlarged nuclei with prominent nucleoli" "Small, pyknotic nuclei with condensed chromatin" "Hyperchromatic nuclei with high DNA content" "Monomorphic nuclei with uniform size" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1044.jpg" -"1045" "What cell characteristic is predominantly observed in the provided microscopic image?" "Lipid-laden macrophages" "Small round cells with high nucleus-to-cytoplasm ratio" "Multinucleated giant cells" "Fibroblastic stromal proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1045.jpg" -"1046" "How do the neoplastic lymphoid cells relate to the epithelial lining of the duct?" "The neoplastic cells show clear signs of invasion into the duct" "The epithelial lining is completely obliterated by the lymphoid cells" "There is a clear demarcation between the neoplastic cells and the duct epithelium" "The neoplastic cells have formed a lymphoepithelial lesion" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1046.jpg" -"1047" "Analyzing the overall pattern of the tissue architecture in the image, which characteristic is NOT present?" "Stroma that lacks specific staining" "Lack of organized structure" "Abundant extracellular matrix" "Distinct glandular structures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1047.jpg" -"1048" "Considering the staining characteristics and morphology, what does the area marked as '3' suggest?" "Vascular proliferation" "Mesh implant" "Granulation tissue" "Dissolving sutures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1048.jpg" -"1049" "What does the brown coloration, as observed in the provided microscopic image, suggest about the characteristics of the stained cells?" "Expression of S-100 protein" "Presence of melanin within the cells" "Accumulation of hemosiderin deposits" "Cytoplasmic expression of keratin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1049.jpg" -"1050" "What cellular characteristic is prominently highlighted by the staining technique used in this image?" "Cytoplasm of the inner cuboidal cells" "Basement membrane of the ductal structures" "Connective tissue matrix" "Nuclei of surrounding connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1050.jpg" -"1051" "Based on the observed morphology and staining patterns, which of the following best describes the arrangement of the ductal structures?" "Atrophied ductal structures with sparse cellular detail" "Regular, organized ductal formations" "Irregular and inflamed ductal structures" "Neoplastic, disorganized ductal formations" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1051.jpg" -"1052" "Which pattern does the distribution of the brown-stained cells follow within the tissue?" "A distinctive overlay" "A peripheral lining" "A random dispersal" "A clustered aggregation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1052.jpg" -"1053" "What do the observed nuclei indicate about the cells in this tissue section?" "Large, hyperchromatic, and irregular nuclei indicative of nuclear atypia" "Vesicular nuclei with small nucleoli characteristic of reactive atypia" "Small, uniform nuclei with dense chromatin consistent with lymphocytes" "Large nuclei with prominent nucleoli representative of glandular epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1053.jpg" -"1054" "What is the predominant staining characteristic of the cytoplasm of the densely infiltrated cells in this image?" "Dark brown staining" "Eosinophilic pink staining" "Basophilic blue staining" "Pale blue staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1054.jpg" -"1055" "What morphological feature is common in the nuclei of the infiltrated cells in this image?" "Lighter blue shade and round to oval" "Multilobed and irregular" "Hyperchromatic and pleomorphic" "Dense heterochromatin clumping" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1055.jpg" -"1056" "Based on the morphology and the pattern of infiltration of cells, what is a likely pathological process illustrated in this image?" "Acute bacterial infection" "Granulomatous inflammation" "Neoplastic cell proliferation" "Chronic inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1056.jpg" -"1057" "Based on the microscopic features observed, which aspect is least representative of normal tissue organization?" "The presence of tissue with basally oriented nuclei" "The presence of varying nuclear-to-cytoplasmic ratios" "The high density and disorganization of cell nuclei" "Uniform staining of the cytoplasm across different cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1057.jpg" -"1058" "Which panel demonstrates the highest level of expression of the target protein based on the intensity of the brown staining?" "Panel a" "Panel b" "Panel c" "Panel d" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1058.jpg" -"1059" "In which panel can you observe a more heterogenous pattern of brown staining, particularly more intense around the periportal area?" "Panel d" "Panel a" "Panel b" "Panel c" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1059.jpg" -"1060" "Which panel indicates minimal expression of the target protein due to very low staining intensity?" "Panel a" "Panel d" "Panel c" "Panel b" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1060.jpg" -"1061" "Based on the pink and purple staining characteristics of this tissue section, what can be inferred about the staining technique used?" "Masson's trichrome" "Giemsa stain" "Periodic acid–Schiff" "Haematoxylin and eosin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1061.jpg" -"1062" "What type of cells are predominantly located within the yellow-circled areas?" "Adipocytes" "Cuboidal epithelial cells" "Spindle-shaped connective tissue cells" "Cells with dense, hyperchromatic nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1062.jpg" -"1063" "What is the predominant cell type within the blue square, indicated by brightly eosinophilic staining?" "Red Blood Cells (RBCs)" "Keratinocytes" "Melanocytes" "Langerhans Cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1063.jpg" -"1064" "What is the predominant feature of the cells observed in this tissue section?" "They display hyperchromatic nuclei." "They have a thin rim of cytoplasm." "They exhibit cytoplasmic basophilia." "They contain multiple nuclei." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1064.jpg" -"1065" "Which feature in the 'Liver' region of the tissue section contradicts the typical histological appearance of hepatocellular carcinoma (HCC)?" "The presence of abundant eosinophilic cytoplasm" "The centralized round to oval nuclei" "The presence of prominent nucleoli" "The irregular arrangement of the cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1065.jpg" -"1066" "Which feature identified within the 'Tumour' section is least indicative of a benign growth?" "Uniform cytoplasmic staining" "Mitotic figures" "Anisokaryosis" "Hyperchromatic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1066.jpg" -"1067" "What characteristic feature does the tissue staining pattern primarily highlight?" "Extracellular matrix components" "Cytoplasmic elements" "Endothelial cell markers" "Cell nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1067.jpg" -"1068" "Based on the cellular morphology, what type of cell is most prominent in this tissue section?" "Neurons" "Squamous epithelial cells" "Adipocytes" "Smooth muscle cells or myofibroblasts" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1068.jpg" -"1069" "The tissue organization observed in the image suggests what type of process?" "Neoplastic process" "Healthy and organized tissue structure" "Inflammatory response" "Regenerating tissue following injury" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1069.jpg" -"1070" "How would you describe the arrangement of the cells present in this microscopic image?" "Palisading" "Herringbone Pattern" "Whorled" "Disorganized" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1070.jpg" -"1071" "Based on the staining characteristics, what stain has likely been used in this microscopic image?" "Wright stain" "Hematoxylin and eosin (H&E) stain" "Periodic acid–Schiff (PAS) stain" "Acid-fast stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1071.jpg" -"1072" "Based on the immunohistochemical staining pattern observed, which marker is most likely being targeted by the antibody used?" "Endothelial cells" "Epithelial cells" "Lymphoid cells" "Neural cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1072.jpg" -"1073" "Based on the morphology observed, what is the likely identity of the cell indicated by the white arrow in the stroma of the gastric mucosa?" "Macrophage" "Plasma cell" "Lymphocyte" "Fibroblast" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1073.jpg" -"1074" "What are the circular, pale-staining structures interspersed among the epithelial cells of the gastric glands?" "Chief cells" "Gastric pits" "Mucin droplets" "Zymogen granules" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1074.jpg" -"1075" "What morphological feature is predominantly exhibited by the nuclei of the large cells in this tissue section?" "Picnotic nuclei" "Hypersegmentation" "Centrally located nuclei" "Multiple nuclei per cell" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1075.jpg" -"1076" "What type of leukocyte predominates in this histological section of the dermis?" "Eosinophils" "Neutrophils" "Basophils" "Monocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1076.jpg" -"1077" "In this section of dermis, which component of the extracellular matrix is readily identifiable by its pink and wavy appearance?" "Reticular fibers" "Fibrin" "Elastin fibers" "Collagen fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1077.jpg" -"1078" "Analyzing the overall preservation of the colonic crypt architecture, how would you describe the crypts observed in this image?" "Crypt shortening and loss" "Elongated and evenly spaced crypts" "Marked crypt hyperplasia" "Crypt distortion with branching" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1078.jpg" -"1079" "Based on the cellular patterns observed, which type of tissue abnormality does the image most likely represent?" "Squamous cell carcinoma" "Adenocarcinoma, not otherwise specified" "Signet ring cell carcinoma" "Melanoma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1079.jpg" -"1080" "Based on the microscopic view of the epithelial tissue, what cellular differentiation feature is prominently absent?" "A stratified squamous arrangement" "A granular layer" "The presence of fibroblasts" "Basal cell proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1080.jpg" -"1081" "What notable feature regarding the keratinized cells can be determined from the epithelial tissue presented in this image?" "Retention of nuclei in the keratinized cells" "The presence of a well-defined granular layer" "Uniform size and shape of keratinized cells" "The complete absence of keratinization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1081.jpg" -"1082" "What histological feature observed in the image aligns with the clinical presentation of guttate psoriasis?" "Elongated dermal papillae" "Clusters of nucleated cells in the upper image" "Intercellular edema in the epidermis" "Neutrophils within the epidermis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1082.jpg" -"1083" "Observing the coloration in the image, which staining technique is most likely to have been used?" "Masson's trichrome stain" "Periodic acid–Schiff (PAS) stain" "Wright's stain" "Hematoxylin and eosin (H&E) stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1083.jpg" -"1084" "Based on the morphology presented in the image, which of the following is NOT a likely feature of the tissue shown?" "There is a lack of significant inflammatory infiltrate" "The tissue represents a chronic renal pathology" "The tissue is undergoing hypertrophic changes" "The tubular segments are experiencing dilation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1084.jpg" -"1085" "In examining the villi in the image, what can be inferred about the gut mucosa?" "Normal villous architecture with elongated and intact villi" "The villi appear shortened and blunted" "The presence of acute inflammatory changes" "Villous atrophy and loss of mucosal height" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1085.jpg" -"1086" "In the portal areas indicated by arrows, what types of cells are primarily contributing to the inflammatory infiltrate?" "Cells with large, pale nuclei and prominent nucleoli" "Cells with larger, vesicular nuclei" "Cells with smaller, hyperchromatic nuclei" "Cells with abundant eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1086.jpg" -"1087" "What is the primary characteristic of the cells indicated by the asterisk in the liver tissue section?" "Hepatocytes undergoing significant necrosis" "Large cells with vesicular nuclei and prominent nucleoli" "Eosinophilic cytoplasm with centrally located nuclei" "Small cells with dense, darkly staining nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1087.jpg" -"1088" "Based on the staining characteristics and morphology, these large cells with brown cytoplasm and pale blue nuclei in the tissue most likely represent:" "Macrophages engaged in phagocytosis" "Neuronal cells expressing neuron-specific enolase" "Adipocytes with lipid droplets" "Fibroblasts involved in extracellular matrix production" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1088.jpg" -"1089" "What is the histological feature indicated by the black arrow in this tissue section?" "Caseous necrosis" "Langhans giant cell" "Keratin pearl formation" "Touton giant cell" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1089.jpg" -"1090" "What characteristic feature indicating a high level of mitotic activity is evident in the cells within this image?" "Cells with hyperchromatic nuclei and irregular shapes" "Cells with ample cytoplasm and multiple, small nucleoli" "Cells with small, dense nuclei and high nucleo-cytoplasmic ratios" "Cells with large, open chromatin nuclei and single conspicuous nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1090.jpg" -"1091" "What type of background stromal features can be seen in this image?" "Abundant adipose tissue with large lipid droplets" "Occasional elongated structures that could represent vessels or connective tissue" "Well-defined layers of collagenous fibers" "Copious extracellular matrix with high cellularity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1091.jpg" -"1092" "Based on the microscopic features observed in the hepatic tissue, which component is not prominently displayed in the image?" "Hepatocyte nuclei" "Erythrocytes within sinusoids" "Vessel branch at the center" "Hepatocyte cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1092.jpg" -"1093" "What feature can be observed within the central tubular structure?" "Keratin debris" "Mucous secretion" "Ciliated epithelial cells" "Inflammatory infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1093.jpg" -"1094" "What is the predominant shape of the nuclei in the cells observed in this image?" "Round to oval" "Hyperchromatic and rounded" "Elongated and spindle-like" "Irregular and pleomorphic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1094.jpg" -"1095" "Considering the staining pattern in this image, which cellular component appears to be most selectively stained?" "Extracellular matrix" "Cytoplasm" "Specific protein expressed by the cells" "Nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1095.jpg" -"1096" "What is the predominant tissue feature observed in this image?" "Loose connective tissue with abundant ground substance" "Skeletal muscle tissue with cross-striations" "Dense fibrous connective tissue with abundant collagen fibers" "Adipose tissue with large clear vacuoles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1096.jpg" -"1097" "Assessing the connective tissue around the tubular structures, what are the characteristics of the spindle-shaped cells?" "They exhibit increased cytoplasmic basophilia." "They are regularly spaced with abundant eosinophilic extracellular matrix." "They are closely packed with minimal extracellular matrix." "They have an irregular spindle shape with hyperchromatic nuclei." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1097.jpg" -"1098" "In the inset image (b), what do the structures highlighted by the special staining technique represent?" "Apoptotic bodies" "Hemoglobin molecules" "Intracellular organisms" "Lipid droplets" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1098.jpg" -"1099" "Which area of the glomerulus displays characteristics most suggestive of segmental glomerulosclerosis?" "Upper-left region with intense pink staining" "Lower-right region with minimal pink staining" "Central region with evenly distributed nuclei" "Lower-left region showing sparse cellularity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1099.jpg" -"1100" "Considering the tissue architecture in the image, which description most accurately reflects its organization?" "Highly organized and repetitive" "Disorganized with loss of normal structure" "Uniform, with distinct cell boundaries" "Monotonous with rare cellular variations" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1100.jpg" -"1101" "Based on the tissue section image, which of the following descriptions best matches the characteristic appearance of the nuclei within the endothelial cells?" "Multilobed nuclei with a coarse chromatin pattern" "Small, hyperchromatic, and irregularly shaped nuclei" "Large, central, elongated nuclei that are lightly stained" "Round, compact nuclei with dense chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1101.jpg" -"1102" "Considering the morphologic features of the nuclei in this slide, which term best describes the observed variability?" "Pleomorphism" "Hyperplasia" "Anisokaryosis" "Monomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1102.jpg" -"1103" "What can be inferred about the pigment seen within the cells in the microscopic image?" "Presence of hemosiderin" "Cytoplasmic accumulation of bilirubin" "Accumulation of lipofuscin" "Deposition of melanin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1103.jpg" -"1104" "Based on the morphological characteristics, which cells found in the dermis likely show evidence of pigment inclusions indicative of melanin?" "Cells with abundant eosinophilic cytoplasm" "Cells displaying nuclear pleomorphism" "Keratinocytes with a granular appearance" "Fibroblasts with spindle-shaped morphology" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1104.jpg" -"1105" "What morphology does the glomerulus structure in the center of the image predominantly exhibit?" "Normal capillary loop structure with an intact Bowman's capsule" "Hypercellularity with increased number of cells in the mesangium" "Crescent formation with extracapillary proliferation" "Hydropic change with clear vacuolation of glomerular cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1105.jpg" -"1106" "Based on the appearance of the tubules surrounding the glomerulus, which characteristic is evident?" "Presence of brush border in all tubular epithelial cells" "Uniform lining of epithelial cells with no evidence of detachment" "Uniformity in the size and shape of tubular epithelial cells" "Variability in size and shape of tubular epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1106.jpg" -"1107" "What histological feature is indicated by the black arrow in the image?" "An inflamed muscle fiber" "An atrophied muscle fiber" "An adipocyte" "A normal muscle fiber" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1107.jpg" -"1108" "Based on the tissue architecture in this image, what is the predominant pathological process occurring?" "Muscle atrophy with fatty infiltration" "Inflammation-induced muscle damage" "Normal muscle regeneration" "Hypertrophic muscle disorder" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1108.jpg" -"1109" "What is the predominant staining characteristic of the multinucleated giant cells observed in the image?" "Basophilic cytoplasm with a single central nucleus" "Eosinophilic cytoplasm with multiple central nuclei" "Eosinophilic cytoplasm with multiple peripheral nuclei" "Basophilic cytoplasm with multiple peripheral nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1109.jpg" -"1110" "Which morphological feature of the cells within the seminiferous tubules is suggestive of a possible pathology?" "Enlarged vesicular nuclei with prominent nucleoli" "Uniform small nuclei" "Multinucleation" "Cytoplasmic vacuolization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1110.jpg" -"1111" "Based on the image, what histological pattern is most consistent with the interface of the cellular components observed?" "Encapsulated nodular pattern" "Diffuse infiltration without a clear boundary" "Well-defined, pushing margin" "Irregular 'mushrooming' invasive projection" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1111.jpg" -"1112" "Which type of tissue appears to be surrounding the neoplastic cells and is being invaded by them?" "Hyalinized collagenous stroma" "Dense fibrous connective tissue" "Skeletal muscle tissue" "Adipose tissue with lipid vacuoles" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1112.jpg" -"1113" "What is the predominant type of cells observed in this tissue section?" "Spherical erythrocytes" "Columnar cells" "Spindle-shaped cells" "Cuboidal cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1113.jpg" -"1114" "Which additional cell type is prominently featured in this image interspersed among spindle-shaped cells?" "Hepatocytes" "Lymphocytes" "Megakaryocytes" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1114.jpg" -"1115" "Which feature in the image suggests the presence of cellular debris or proteinaceous material within the renal tubules?" "The areas highlighted with yellow stars" "The lighter pink staining of the connective tissue" "The dark-stained nuclei of the tubular cells" "The areas indicated by the black arrow" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1115.jpg" -"1116" "What does the black arrow in the image most likely indicate regarding the renal tissue?" "Expanded connective tissue" "Normal glomerular structure" "Necrotic tubular cells" "Healthy renal tubules" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1116.jpg" -"1117" "Based on the staining characteristics, what can you infer about the targeted antigen's cellular localization?" "The antigen is distributed throughout the extracellular matrix" "The antigen is predominantly nuclear" "The antigen is cytoplasmic with dense aggregates in some areas" "The antigen is localized mostly on the cell membrane" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1117.jpg" -"1118" "Based on the cellular arrangement observed in the tissue section, which architectural pattern is predominantly exhibited?" "Sheets and nests" "Papillary structures" "Glands and rosettes" "Concentric, whorl-like formations" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1118.jpg" -"1119" "Regarding the stroma visible in the main image, what is the most accurate description of its composition?" "Dense network of collagenous fibers" "Largely acellular, myxoid substance" "Abundant adipose tissue" "Heavy infiltration of inflammatory cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1119.jpg" -"1120" "Focusing on the peripheral insert, what is the pattern of the brown staining indicative of immunohistochemical reactivity?" "Staining within the extracellular matrix" "Nuclear localization" "Cytoplasmic localization" "Membranous distribution" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1120.jpg" -"1121" "Based on the presence of numerous small nucleated cells in the background, what is the most likely accompanying pathology in this tissue sample?" "Granulomatous inflammation" "Apoptotic cell death" "Chronic inflammation" "Acute inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1121.jpg" -"1122" "Interpreting the cellular characteristics in the image, what histological feature do the smaller cells with high nuclear-to-cytoplasmic ratios, which lack the brown staining, most likely represent?" "Neoplastic epithelial cells" "Red blood cells" "Lymphocytes" "Connective tissue cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1122.jpg" -"1123" "What is the predominant morphological characteristic of the immune cells clustering around the necrotic area?" "The cells have hyperchromatic nuclei" "The cells have small, round nuclei" "The cells display multi-nucleation" "The cells have elongated, plump nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1123.jpg" -"1124" "Based on the immunohistochemical staining depicted in the image, which marker is most likely highlighted around the cell membranes?" "Keratin" "CD3" "CD20" "HMB45" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1124.jpg" -"1125" "Analyzing the cellular infiltrate around the lesion, which of the following findings would be consistent with an ongoing inflammatory process?" "Adipocyte atrophy" "Inflammatory cells with varied sizes and staining characteristics" "Hemorrhage" "Eosinophilic infiltration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1125.jpg" -"1126" "What does the appearance of cells with clear cytoplasm signify in the context of the glandular formations observed in the image?" "Presence of intranuclear inclusions" "Accumulation of mucin within the cytoplasm" "High lipid content within the cells" "Artifactual clearing due to technical processing" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1126.jpg" -"1127" "Based on the staining pattern, which stains have been used in this microscopic image?" "Wright-Giemsa stain" "Periodic acid–Schiff (PAS) and Alcian blue" "Hematoxylin and eosin (H&E)" "Masson's trichrome stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1127.jpg" -"1128" "What feature characterizes the large clusters of cells situated centrally and to the left in this skin tissue section?" "Dense eosinophilic cytoplasm and peripheral nuclei" "Clear cells with prominent nucleoli and increased nuclear-cytoplasmic ratio" "Foamy cytoplasm with centrally placed nuclei" "Hyperchromatic nuclei and increased mitotic figures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1128.jpg" -"1129" "In the tissue section presented, what does the structure resembling an onion in the top right section most likely represent?" "A hair follicle" "A sudoriferous (sweat) gland" "A sebaceous gland" "A nerve bundle" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1129.jpg" -"1130" "Within the pink-staining connective tissue in this skin tissue section, what is the nature of the clear, empty spaces seen throughout?" "Blood vessel lumina" "Lymphatic spaces" "Areas of tissue artifact" "Adipose tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1130.jpg" -"1131" "In the image provided, which labeled area demonstrates the characteristic feature known as Verocay bodies, visible as rows of nuclei separated by an eosinophilic substance?" "Area A" "Area V" "Area H" "Area B" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1131.jpg" -"1132" "Examining the image closely, where would you find evidence of hemosiderin deposits, which are a byproduct of blood degradation?" "In Area V" "Adjacent to Area A" "Within Area B" "Near the vessel indicated by the red arrow" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1132.jpg" -"1133" "What is the predominant staining characteristic of the connective tissue at the top portion of the image?" "Predominantly eosinophilic with sparse nuclei" "Mixed basophilic and eosinophilic with moderate nuclei" "Predominantly basophilic with lots of nuclei" "Predominantly eosinophilic with abundant nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1133.jpg" -"1134" "What does the blue staining in the portal areas indicate in this liver tissue specimen?" "Hematoxylin staining of nuclei" "Accumulation of bile pigment" "Collagen deposition associated with fibrotic changes" "Increased glycogen storage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1134.jpg" -"1135" "Based on cytoplasmic staining characteristics seen in the image, what type of staining method is likely used?" "Periodic acid-Schiff (PAS)" "Hematoxylin and eosin (H&E) stain" "Masson's trichrome" "Giemsa stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1135.jpg" -"1136" "What is the predominant cytoplasmic staining characteristic of the cells in this microscopic image?" "Acidophilic with a pink to red coloration" "Neutrophilic with a tan to brown coloration" "Amphiphilic with fluctuating coloration" "Basophilic with a blue to purple coloration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1136.jpg" -"1137" "How would you describe the appearance of the nuclei within these cells?" "The nuclei are round with uniform shape and size and prominent nucleoli" "The nuclei are hyperchromatic with smokey chromatin and multiple nucleoli" "The nuclei are irregular in shape with variable sizes and inconspicuous nucleoli" "The nuclei are elongated with an irregular distribution across the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1137.jpg" -"1138" "What defines the central structure being indicated by the arrow in the bone marrow tissue?" "A neoplastic proliferation of plasma cells" "A cluster of erythroid precursors" "A granuloma composed of epithelioid cells and multinucleated giant cells" "An aggregate of predominantly lymphoid cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1138.jpg" -"1139" "Based on the density of cells in the dermis and the arrangement of collagen, what can be inferred about the inflammatory activity from this histological section?" "The skin sample suggests a reduced inflammatory infiltrate." "There is a significant inflammatory infiltrate present similar to acute inflammation." "There is a dense, chronic inflammatory infiltrate present." "The cell density and collagen arrangement indicate a granulomatous inflammation." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1139.jpg" -"1140" "Based on the image, what is the dominant morphological feature of the cells surrounding the centralized structure?" "Spindle-shaped cells with elongated nuclei" "Squamous cells with abundant intercellular bridges" "Polygonal cells with abundant cytoplasm" "Round cells with small, hyperchromatic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1140.jpg" -"1141" "How would you describe the extracellular matrix present in the left side of the image?" "Dense with extensive calcification" "Lightly stained and fibrillar" "Basophilic with a mucinous appearance" "Abundant and eosinophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1141.jpg" -"1142" "Assessing the arrangement of cells in this tissue sample, how would you describe their organization?" "Highly organized with tight cellular packing" "Radially organized around a central lumen" "Well-organized in duct-like structures" "Disorganized with a lack of glandular architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1142.jpg" -"1143" "Based on the morphological features observed in the histological section, what characteristic is NOT shared by the prominently indicated cells (pointed out with arrows)?" "Multiple nucleoli within the nuclei" "Abundant basophilic cytoplasm" "Predominantly eosinophilic cytoplasm" "Eccentrically located nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1143.jpg" -"1144" "In this histological section stained with H&E, which component appears basophilic in the indicated cells?" "Extracellular matrix" "Cytoplasm" "Nuclei" "Vascular structure" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1144.jpg" -"1145" "Based on the image, how would you describe the cellularity of the tissue?" "Low cellularity with scarce extracellular matrix" "High cellularity with scarce extracellular matrix" "Low cellularity with abundant extracellular matrix" "High cellularity with abundant extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1145.jpg" -"1146" "Identify the structure indicated by the arrow in the image." "A mitotic figure" "An area of necrosis" "A benign inclusion" "An apoptotic body" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1146.jpg" -"1147" "In the topmost layer of the articular cartilage section, what is the arrangement and shape of the chondrocytes observed?" "Flattened chondrocytes arranged densely" "Sparse, vertically aligned chondrocytes" "Spherical chondrocytes arranged in columns" "Chondrocytes embedded within a calcified matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1147.jpg" -"1148" "What aspect of the image suggests that the tubular structure on the right is likely an artery and not a vein?" "Uneven staining of the wall" "A smaller, open lumen that maintains its shape" "A larger lumen compared to the left structure" "The presence of concentric layers of cells surrounding the lumen" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1148.jpg" -"1149" "How would you describe the nuclear characteristics of the cells in this tissue sample?" "Highly pleomorphic nuclei with hyperchromatic features" "Elongated nuclei with evenly dispersed chromatin" "Small, round nuclei with inconspicuous nucleoli" "Uniform round nuclei with homogenous chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1149.jpg" -"1150" "Based on the microscopic image, what is indicated by the presence of vessels with red blood cells in the stroma?" "Evidence of angiogenesis within the tumor" "Normal vascular supply to the tissue" "Inflammation and increased vascularity due to infection" "Hemorrhage within the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1150.jpg" -"1151" "Based on the cellular and tissue morphology observed at 100x magnification, which feature most accurately describes the overall tissue architecture?" "A uniform, well-organized layer of cells" "Clear demarcation between different tissue types" "A disordered structure with a dense proliferation of cells" "Even distribution of keratin or collagen deposits" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1151.jpg" -"1152" "What feature is indicated by the small arrows in the image?" "Neutrophils with multilobed nuclei" "Lymphocytes with hyperchromatic nuclei" "Keratinocytes with abundant cytoplasm" "Epithelioid histiocytes with well-defined cell boundaries and centrally placed nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1152.jpg" -"1153" "What does the large arrow in the image likely indicate?" "A vascular structure with erythrocytes" "An adipocyte with a central fat vacuole" "A multinucleated giant cell with multiple nuclei" "A dysplastic cell with nuclear atypia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1153.jpg" -"1154" "What characteristic feature of the glomerulus can be observed in this PAS-stained light microscopic image?" "Uniformly thin capillary loops" "Normal distribution of mesangial cells" "Well-preserved capillary lumina" "Collapsed and hypercellular glomerular tuft" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1154.jpg" -"1155" "What other pathological change can be inferred from the morphology seen in this PAS-stained image?" "Reduction in the number of podocytes" "Proliferation of capillary endothelial cells" "Decrease in tubular epithelial cell size" "Segmental sclerosis within the glomerulus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1155.jpg" -"1156" "Upon examining the cellular morphology, what feature is NOT present that would suggest a more aggressive neoplastic behavior?" "High mitotic activity" "Presence of significant inflammatory infiltrate" "Areas of necrosis" "Abundant eosinophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1156.jpg" -"1157" "Which of the following features visible in the image aligns with the typical characteristics of a mesenchymal tumor?" "Copious intra-cellular glycogen" "Abundant myxoid matrix" "Well-formed glandular structures" "Indistinct cell borders with scant stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1157.jpg" -"1158" "What cytological feature can be identified at higher magnification as indicated by the inset?" "Syncytial aggregates" "Mitotic figures" "Nuclear grooves" "Macronucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1158.jpg" -"1159" "Analyzing the general architecture of this tissue section, what does the observed lobular organization most likely represent?" "The delineated zones of a liver lobule" "The typical lobular structure of testicular tissue" "The characteristic appearance of renal glomeruli" "An indication of splenic white pulp regions" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1159.jpg" -"1160" "Considering the description of the cytoplasm, which finding would align with the suspected pathology of the cells?" "Lipid-laden cytoplasm" "Clear and vacuolated cytoplasm" "Scant eosinophilic cytoplasm" "Abundance of eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1160.jpg" -"1161" "What feature of the endothelial cells lining the structures indicates the possibility of a specific immunohistochemical marker being used in this tissue section?" "Presence of cilia on the endothelial cells" "Brown pigmentation of the endothelial cells" "Multinucleation of endothelial cells" "Presence of microvilli on the endothelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1161.jpg" -"1162" "Examining the tissue section, what is the likely nature of the gaps or interruptions seen in the endothelial lining of the tubular structures?" "Artifact from tissue processing" "Evidence of endothelial cell hypertrophy" "Normal variability in endothelial lining" "Indicative of vascular invasion by a surrounding malignant tumor" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1162.jpg" -"1163" "Based on the cellular morphology, what could be the likely lineage of the cells in the lower half of the image?" "Follicular cells with features typical of benign thyroid tissue" "Cells with larger eosinophilic cytoplasm consistent with squamous carcinoma" "Cells indicative of lymphocytic infiltration, such as in thyroiditis" "Neuroendocrine cells typically seen in medullary carcinoma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1163.jpg" -"1164" "What does the brown cytoplasmic staining observed in the cells most likely indicate?" "Accumulation of hemosiderin" "Expression of a specific antigen" "Presence of lipofuscin granules" "Areas of necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1164.jpg" -"1165" "What feature of the given glomerulus is indicative of a pathologic alteration?" "Formation of a fibroepithelial crescent" "Thickening of the basement membrane" "Expansion of mesangial matrix" "Presence of podocyte effacement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1165.jpg" -"1166" "Based on the PAS-stained image, which area shows evidence of stromal fibrosis?" "Areas with loose and disorganized tissue matrix" "Areas with dense and more disorganized tissue pattern" "Regions with magenta-pink staining and organized cellularity" "Regions with cellularity within the mesangium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1166.jpg" -"1167" "What characteristic is predominantly displayed by the nuclei in the cellular infiltrate seen in the histologic section?" "Hyperchromatism" "Prominent nucleoli" "Multinucleation" "Significant pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1167.jpg" -"1168" "How would you describe the cellular arrangement in the image?" "Papillary structures" "Cells with well-defined borders" "Gland formation" "Syncytial arrangement" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1168.jpg" -"1169" "Based on the histological features observed, which of the following best fits the description of the extra-cellular matrix present?" "Hyalinized fibrous tissue" "Cartilaginous matrix" "Myxoid stroma" "Eosinophilic fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1169.jpg" -"1170" "What type of cells line the cystic structure observed in the microscopic image?" "Flattened epithelial cells" "Adipocytes" "Ciliated columnar epithelial cells" "Stratified squamous epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1170.jpg" -"1171" "In the image of the arterial tissue, what does the specific brownish staining observed in the innermost and outermost layers most likely indicate?" "Calcium buildup within the tissue" "Necrosis within the tissue" "Presence of smooth muscle cells" "Immunoreactivity for a molecule of interest" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1171.jpg" -"1172" "Where are the nuclei primarily located, as indicated by dark, round to ovoid structures in the arterial tissue cross-section?" "Visible throughout the tissue layers" "Exclusively in the adventitia" "Exclusively in the endothelium" "Throughout the tunica media only" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1172.jpg" -"1173" "What is the most notable staining pattern observed in the nuclei of the cells?" "Predominant blue staining with scattered brown nuclei" "Patchy brown staining with clear areas" "Absence of brown staining" "Homogenous brown staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1173.jpg" -"1174" "What can be inferred about the expression level of the target antigen?" "There is consistent expression across the majority of cells" "Only the cytoplasm shows positive staining for the antigen" "There is high variability in expression levels across cells" "Expression is limited to a few cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1174.jpg" -"1175" "Based on the staining pattern, how would you characterize the population of cells?" "Mixed population with varying degrees of staining intensity" "Homogeneous population with uniform cell sizes and shapes" "Homogeneous population with significant cytoplasmic staining" "Heterogeneous population with varying cell sizes and shapes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1175.jpg" -"1176" "Based on the staining pattern observed, what does the brown coloration predominantly signify?" "Hematoxylin staining of nucleic acids" "Immunohistochemical staining demonstrating antibody binding" "Negative control with no specific staining" "Eosin staining of extracellular matrix components" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1176.jpg" -"1177" "In reviewing the muscular layer at the top portion of the image, how would you describe the alignment of the muscle fibers?" "The muscle fibers are aligned circumferentially with oval nuclei." "The muscle fibers are fragmented and demonstrate varying staining intensities." "The muscle fibers are irregularly arranged with no distinct pattern." "The muscle fibers are aligned longitudinally with elongated nuclei." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1177.jpg" -"1178" "What feature suggests that the prominent cell in the center of the image is involved in the process of phagocytosis?" "Abundant blue-stained cytoplasm" "A clear, unobstructed view of the nucleus" "Presence of multiple nuclei" "Inclusions resembling red blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1178.jpg" -"1179" "Which of the following best describes the appearance of the cell cytoplasm of the large central cell?" "Vacuolated and clear" "Scarce and faintly stained" "Dense and uniformly stained" "Abundant with a foamy texture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1179.jpg" -"1180" "Based on the cellular morphology observed in the image, which cell type appears to be more prevalent?" "Neurons" "Macrophages" "Epithelioid cells" "Adipocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1180.jpg" -"1181" "What cellular growth pattern can be inferred from this microscopic image?" "Rosette formation" "Well-circumscribed nesting" "Papillary" "Diffuse" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1181.jpg" -"1182" "What characteristic of the cellular staining pattern is most evident in this immunochemical-labeled tissue section?" "Peripheral (membrane) staining of cells" "Diffuse cytoplasmic staining" "Staining absent in cellular structures" "Nuclear localization of the stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1182.jpg" -"1183" "What additional structural feature can be identified in the tissue section suggesting a degree of cellular disorganization?" "Absence of any intercellular connections" "Pseudostratification with overlapping of nuclei" "Homogenous staining throughout the tissue section" "The presence of a thick extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1183.jpg" -"1184" "Based on the intensity of brown staining observed in the cytoplasm, how would you score the level of immunoreactivity for TGF-β1?" "Moderate" "Weak" "Strong" "Negative" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1184.jpg" -"1185" "Evaluating the cellular morphology, the shape of the cells within the tissue primarily appears to be:" "Regular with consistent sizing" "Uniform and round" "Uniform and regular" "Irregular with some variation in size" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1185.jpg" -"1186" "Considering the overall architecture of the tissue, what is the pattern of cell growth in this image?" "Organized and structured" "Disorganized and disrupted" "Mostly uniform with minimal disruption" "Disorganized with some structured areas" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1186.jpg" -"1187" "What does the mesangial region of the glomerulus predominantly indicate?" "Normal cellularity with minimal matrix expansion" "Atrophy and fibrosis" "Increased matrix material and cellularity" "Extensive deposition of immune complexes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1187.jpg" -"1188" "Based on the cellular morphological features observed, what is the nature of the tissue's inflammatory response?" "Chronic inflammation with lymphocytic infiltration" "Granulomatous inflammation with multinucleated giant cells" "Fibrinous inflammation with exudate rich in fibrin" "Acute inflammation with predominant neutrophil presence" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1188.jpg" -"1189" "Based on the characteristics of the superficial cells, what is the most accurate description of their nuclear features?" "The nuclei are vesicular with prominent nuclear inclusions." "The nuclei are hyperchromatic and exhibit increased pleomorphism." "The nuclei are pyknotic and the cells are flattened." "The nuclei are large and show prominent nucleoli." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1189.jpg" -"1190" "Based on the observed histopathological features, what is the level of cellular cohesion in the suprabasal layer?" "Cells are arranged in a hyperplastic manner without gaps" "Cells show standard intercellular connections" "Cells demonstrate increased cohesion and compactness" "Cells exhibit loss of cohesion and are loosely arranged" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1190.jpg" -"1191" "What can be observed in the cytoplasm of the cells indicated by the arrowheads?" "A foamy appearance with numerous small vacuoles." "A large number of prominent granules." "A perinuclear halo." "Multiple vacuoles throughout the cytoplasm." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1191.jpg" -"1192" "Based on the features observed in the image, what hematological phenomenon is illustrated by the erythrocytes (red blood cells)?" "Poikilocytosis" "Anisocytosis" "Agglutination" "Rouleaux formation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1192.jpg" -"1193" "What myeloid lineage maturity stage can be observed among the cells in this image?" "Myeloblasts" "Segmented neutrophils" "Myelocytes" "Promyelocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1193.jpg" -"1194" "What notable feature is observed in the thyroid follicles present in this histological section?" "Reduction or absence of colloid material" "Prominence of parafollicular cells within the follicles" "Uniform colloid distribution" "Presence of numerous pink-staining erythrocytes within the follicles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1194.jpg" -"1195" "Which of the following cellular features is NOT readily identifiable in the provided connective tissue image?" "Active fibroblasts" "Ground substance" "Eosinophilic collagen fibers" "Adipocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1195.jpg" -"1196" "What pathological feature is not visible in the current field of view of this liver tissue section?" "Portal spaces" "Fibrosis" "Central venulitis" "Hepatocellular carcinoma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1196.jpg" -"1197" "Based on the histological features observed, which cellular morphology is most consistent with the structures resembling endothelial ingrowths?" "Finger-like formations with hyalinized central cores" "Spindle-shaped cells with elongated nuclei" "Honeycomb pattern of uniform cells with small nuclei" "Large, round cells with prominent nucleoli and abundant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1197.jpg" -"1198" "What staining technique can be inferred from the image due to the coloration of the nuclei and extracellular matrix?" "Periodic Acid–Schiff (PAS)" "Masson's Trichrome" "Papanicolaou (Pap) stain" "Hematoxylin and Eosin (H&E)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1198.jpg" -"1199" "How would you describe the epithelial component of the duct-like structures in this tissue sample?" "Appears as a single layer of uniform cells" "Lined by a bilayered epithelium" "Lacks any sort of lining epithelium" "Characterized by significant pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1199.jpg" -"1200" "What cellular structure is indicated by the yellow arrow in the provided renal tissue image?" "Collecting duct" "Distal convoluted tubule" "Glomerulus" "Proximal convoluted tubule" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1200.jpg" -"1201" "Based on the image, how would you describe the sinusoids in this section of liver tissue?" "Lined by flat endothelial cells" "Widened and engorged with blood" "Containing numerous red blood cells" "Indistinct and difficult to discern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1201.jpg" -"1202" "What observation indicates that the hepatic architecture is intact in this image of liver tissue?" "Hepatic cords radiating outward from the central vein" "Presence of significant fibrosis" "Disorganized arrangement of hepatocytes" "Uniform size and shape of hepatocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1202.jpg" -"1203" "What histological feature characterizes the large cells with clear spaces?" "Hyperchromatic nuclei" "Multinucleation" "Peripheral nuclei" "Abundant eosinophilic cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1203.jpg" -"1204" "How can the dense cellular infiltrate be distinguished from the adipocytes in the tissue?" "Abundant, clear cytoplasm" "Hyperchromatic nuclei with scant cytoplasm" "Large, prominent nuclei" "Large clear spaces" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1204.jpg" -"1205" "Based on the tissue morphology present in the image, what is the most likely type of muscle tissue depicted?" "Smooth muscle" "Cardiac muscle" "Skeletal muscle" "No muscle tissue is present" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1205.jpg" -"1206" "Based on the cellular morphology seen in the image, what type of chromatin pattern is most consistent with the histological appearance?" "Homogeneous chromatin" "Salt-and-pepper chromatin" "Clumped chromatin" "Fine, dispersed chromatin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1206.jpg" -"1207" "In the image, which area should be of particular interest when evaluating for the presence of gland-like structures?" "The areas with pink to eosinophilic cytoplasm" "The areas with purple-blue coloration" "The upper left section which appears less cellular" "The densely packed area with hyperchromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1207.jpg" -"1208" "What staining technique is indicated by the coloration patterns observed in the histological image?" "Masson's trichrome stain" "Hematoxylin and eosin (H&E) stain" "Papanicolaou stain" "Periodic acid-Schiff (PAS) stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1208.jpg" -"1209" "What cell type might be presumed by the presence of kidney or bean-shaped nuclei within the cells?" "Neutrophils" "Myocytes" "Plasma cells" "Macrophages" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1209.jpg" -"1210" "What is the nature of the underlying layer beneath the epithelium in the image?" "Adipose tissue" "Dense connective tissue with low cellular density" "Hyaline cartilage" "Loose connective tissue with high cellular density" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1210.jpg" -"1211" "Based on the histological features observed in the image, what type of cellular arrangement is depicted within the oval-shaped structure?" "Multinucleated giant cells" "Large cells with abundant clear cytoplasm" "Uniformly spaced cells with hyperchromatic nuclei" "Disorganized and pleomorphic cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1211.jpg" -"1212" "Based on the microscopic image, how would you characterize the nuclei of the cells present?" "Highly pleomorphic with prominent nucleoli" "Hyperchromatic with irregular borders" "Uniformly small and round" "Small, with condensed chromatin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1212.jpg" -"1213" "Identify the type of structures indicated by the presence of open spaces within the tissue section." "Sinusoidal spaces of the liver" "Alveolar structures of the lung" "Tubular structures of the kidney" "Villous structures of the small intestine" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1213.jpg" -"1214" "What is the appearance of the cytoplasm in the endothelial cells lining the vascular structures?" "Abundant with clear boundaries" "Copious with many granules" "Densely packed with large organelles" "Scant and not prominent" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1214.jpg" -"1215" "From the histological structure observed, what morphological feature is indicated?" "Signet-ring cell morphology" "Psammoma body formation" "Hobnailing" "Hyperchromatic clustering" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1215.jpg" -"1216" "What type of matrix material can be identified in this tissue section?" "Basophilic stippled matrix" "Eosinophilic, amorphous matrix" "Myxoid matrix" "Chondroid matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1216.jpg" -"1217" "Compared to the surrounding smaller lymphocytes, how does the cytoplasm of the larger cells appear?" "More ample and paler" "Darker and more granular" "Similar in appearance with no distinguishable differences" "More condensed and deeply eosinophilic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1217.jpg" -"1218" "Which observation in the given image does not align with the characteristics of the proliferations of round cells indicated by the arrowhead?" "Cells exhibit prominent nucleoli" "Cells possess prominent nuclei" "Cells appear small and monomorphic" "Cells are densely packed within the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1218.jpg" -"1219" "Regarding the nuclear morphology, which characteristic is commonly observed in the cells present in this image?" "Nuclei with multiple, prominent nucleoli" "Nuclei with uniform, small size and shape" "Nuclei with dispersed chromatin and small, inconspicuous nucleoli" "Nuclei with dense chromatin and indistinct nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1219.jpg" -"1220" "What does the architectural organization of the cells in this image suggest?" "A disorganized, dense arrangement of cells" "The presence of adipocytes interspersed among the cells" "A regular patterning consistent with normal bone marrow" "The presence of mature hematopoietic elements" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1220.jpg" -"1221" "Based on the cytoplasmic features observed in the cells, how would you describe the amount of cytoplasm present?" "Abundant cytoplasm with a basophilic staining" "Moderate to abundant cytoplasm with vacuolation" "Moderate volume of cytoplasm with eosinophilic staining" "Scant cytoplasm with neutral staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1221.jpg" -"1222" "What type of muscle tissue is represented in the microscopic image based on the structural characteristics observed?" "Skeletal muscle tissue" "Cardiac muscle tissue" "Non-muscle soft tissue" "Smooth muscle tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1222.jpg" -"1223" "Identify the type of cells marked by arrows in the displayed liver tissue section." "Lymphocytes" "Hepatocytes" "Erythrocytes" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1223.jpg" -"1224" "Based on the staining characteristics, what can be inferred about the nuclei of the cells?" "The nuclei are small and hyperchromatic without visible nucleoli" "The nuclei are enlarged with an increased nuclear-to-cytoplasmic ratio" "The nuclei are hyperchromatic with prominent nucleoli" "The nuclei are vesicular with inconspicuous nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1224.jpg" -"1225" "What is the morphology of the nuclei of the cells in the surrounding ovarian stroma?" "Elongated and spindle-shaped" "Round with prominent nucleoli" "Vesicular with multiple nucleoli" "Irregular and hyperchromatic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1225.jpg" -"1226" "In the image, what is the histological pattern presented by the nuclei surrounding the central necrobiotic area?" "The nuclei display a linear and palisading arrangement." "Nuclei are arranged in concentric rings known as an onion-skin pattern." "The nuclei are hyperchromatic with pleomorphic features." "There is a disorganized arrangement of swollen nuclei." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1226.jpg" -"1227" "What is the predominant chromatin pattern observed in the nuclei of the cells in this tissue section?" "Stippled" "Coarse and clumped" "Invisible under staining" "Uniformly dispersed" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1227.jpg" -"1228" "Based on the cellular arrangement and morphology in the image, what is the most apparent feature?" "Presence of elongated muscle fibers" "Dense cellular arrangement with varying cell shapes" "Regular, consistent architecture" "Abundant adipose tissue cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1228.jpg" -"1229" "What feature is most characteristic of the centrally located structure in comparison to the surrounding densely packed cells?" "Presence of abundant cytoplasm" "Similar size and shape to surrounding cells" "More intense brown staining" "Less intense brown staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1229.jpg" -"1230" "Based on the morphology of the tightly packed cells, what is the most likely characteristic of their differentiation?" "Organized differentiation into glands" "Lack of organized tissue structure differentiation" "Differentiation into adipose tissue" "Presence of squamous differentiation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1230.jpg" -"1231" "Considering the morphological characteristics visible in the ductal structures, what could the rounded, intracytoplasmic inclusions observed with magenta staining most likely represent?" "Keratohyalin granules" "Russell bodies" "Melanin pigment" "Lipofuscin granules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1231.jpg" -"1232" "What characteristic feature is indicated by the red arrows in the microscopic image?" "Mitotic figures" "Mesothelial windows" "Cytoplasmic inclusion bodies" "Hyperchromatic nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1232.jpg" -"1233" "What does the brown staining pattern in the image predominantly indicate about the cells?" "The presence of necrotic tissue" "An artefact from the staining process" "A high glycogen content in the cells" "The presence of S-100 protein expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1233.jpg" -"1234" "Based on the microscopic features, which layer of the arterial wall is the most thickened?" "The lumen" "The intima" "The media" "The adventitia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1234.jpg" -"1235" "Identify the region that shows evidence of a lymphocytic infiltrate." "The adventitia" "The media" "The lumen" "The endothelial lining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1235.jpg" -"1236" "Based on the observed features in the microscopic image, what can be inferred about the nuclear characteristics of these cells?" "The nuclei are predominantly small and pyknotic." "The nuclei show uniform size and shape." "The nuclei have a low nuclear-to-cytoplasmic ratio." "The nuclei exhibit anisokaryosis with hyperchromasia." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1236.jpg" -"1237" "Based on the histological features observed, which of the following best characterizes the architectural complexity of the glands?" "The glands exhibit significant folding within their structure." "There is evidence of extensive glandular branching." "The glands have irregular outlines but no clear complex architecture." "The glandular structures maintain a tubular shape without complex features." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1237.jpg" -"1238" "What does the central portion of the circular entity most closely resemble in this cross-sectional view?" "Bacterial colony formation" "Normal cell organelles" "Parasitic hooklets" "Viral inclusion bodies" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1238.jpg" -"1239" "What does the presence of smaller, round cells with dense nuclei surrounding the circular entity indicate?" "Adipose tissue" "Presence of neoplastic cells" "Hematopoietic activity in bone marrow" "Inflammatory response with leukocyte infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1239.jpg" -"1240" "What feature is indicated by the brownish coloration present in many of the cell's cytoplasm?" "Glycogen accumulation" "Positive pancytokeratin staining" "Negative pancytokeratin staining" "Lipofuscin pigment" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1240.jpg" -"1241" "What cellular activity is most likely indicated by the brown-stained nuclei in sections B and D?" "Mitotic activity" "Protein synthesis" "Necrotic changes" "Apoptotic activity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1241.jpg" -"1242" "Based on the image, which description best characterizes the architectural pattern of the gland-like structure?" "Well-formed ducts with ample myoepithelial cells" "Micropapillary pattern with infiltrative growth" "Cystic spaces lined by flattened epithelium" "Uniform acinar structures with dense fibrotic stroma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1242.jpg" -"1243" "What additional cellular component is prominently featured in the stroma surrounding the gland-like structure?" "Extracellular mucin deposits" "Well-differentiated adipocytes with large lipid droplets" "Dense clusters of inflammatory cells" "Regularly arranged smooth muscle cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1243.jpg" -"1244" "Based on the tissue architecture and staining characteristics observed in the image, what is the most likely histological feature present in this field?" "Hyperplastic epithelia" "Acute inflammatory infiltrate" "Granulomatous inflammation" "Dysplastic cellular changes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1244.jpg" -"1245" "What feature indicates that there is a high expression of the target antigen in the cells observed in the image?" "Homogeneity in cellular size and shape" "Darker nuclei in a subset of cells" "Uniform staining intensity across all cells" "Consistently prominent cytoplasmic staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1245.jpg" -"1246" "Based on the nuclear characteristics observed in the image, what kind of cellular morphology is suggested?" "Anisonucleosis" "Monomorphism" "Pleomorphism" "Isokaryosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1246.jpg" -"1247" "Assessing the arrangement of the cells with brown-stained nuclei, which option best describes their organization?" "Dispersed without a clear pattern" "Organized in well-defined lobules" "Forming glandular structures" "Arranged in sheets or nests" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1247.jpg" -"1248" "Regarding the macroconidia observed in the image, what is their most notable morphological feature?" "They are small and inconspicuous" "They have a thick wall" "They are multinucleate" "They exhibit tuberculate surfaces" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1248.jpg" -"1249" "What characteristic features are indicated by the white arrows in the image?" "Eosinophilic cytoplasm and cross-striations" "Increased nuclear-to-cytoplasmic ratio" "Anisocytosis and anisokaryosis" "Pleomorphism and hyperchromatic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1249.jpg" -"1250" "What distinctive cellular inclusion can be observed within the macrophages in this PAS-stained tissue section?" "Rod-shaped inclusion bodies" "Crystalline structures" "Lipid droplets" "Nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1250.jpg" -"1251" "Which follicle is characterized by a single layer of flattened granulosa cells surrounding the oocyte?" "The follicle indicated by the black arrow" "None of the above" "The follicle indicated by the red arrow" "The follicle indicated by the blue arrow" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1251.jpg" -"1252" "What distinguishes the primary follicle marked by the blue arrow from the other follicles?" "A single layer of cuboidal granulosa cells" "Fluid-filled antrum inside the follicle" "Presence of multiple layers of granulosa cells" "Flattened granulosa cells surrounding the follicle" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1252.jpg" -"1253" "Identify the characteristics of the follicle pointed out by the red arrow." "It has a prominent antrum visible at this magnification" "It has a single layer of flattened granulosa cells" "It is surrounded by multiple layers of granulosa cells" "It is surrounded by a single layer of cuboidal granulosa cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1253.jpg" -"1254" "What predominant cell type can be identified in this tissue section based on morphology?" "Fibroblasts" "Epithelial cells" "Adipocytes" "Neurons" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1254.jpg" -"1255" "Which staining pattern suggests the presence of immune cells in this tissue sample?" "Red intracellular staining" "Pink extracellular background staining" "Brown cytoplasmic staining" "Blue nuclear staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1255.jpg" -"1256" "Based on the morphology of the cells observed in this high-power field, which type of neoplastic cells predominate?" "Small round blue cells with high nuclear-to-cytoplasmic ratio" "Squamous cells with abundant keratin" "Lymphoid cells with scanty cytoplasm" "Signet ring cells with clear cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1256.jpg" -"1257" "What cell types predominate in the inflammatory infiltrate surrounding the dilated vessels?" "Basophils" "Macrophages" "Lymphocytes" "Eosinophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1257.jpg" -"1258" "What is the pattern of nuclei distribution in the muscle fibers as seen in this muscle biopsy?" "Multiple nuclei in a row" "No visible nuclei" "Central nucleation" "Peripheral nucleation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1258.jpg" -"1259" "The brown deposits marked by black arrows in the muscle biopsy are consistent with the presence of which protein complex?" "Myosin protein aggregates" "Sarcoplasmic reticulum expansion" "Complement component C5b-9" "Mitochondrial accumulations" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1259.jpg" -"1260" "Based on the cellular morphology seen in the image, what type of nuclear alteration is most prevalent?" "Nuclear molding" "Nuclear uniformity" "Prominent nucleoli" "Nuclear elongation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1260.jpg" -"1261" "In terms of cytoplasmic staining, how would you characterize the majority of the cells in the image?" "Deeply eosinophilic" "Homogeneously basophilic" "Pale cytoplasm with perinuclear halos" "Variably eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1261.jpg" -"1262" "Based on the morphology of the large cells in the main image, what is the most likely lineage of the hematopoietic precursor cells observed?" "Lymphoid lineage" "Myeloid lineage" "Erythroid lineage" "Megakaryocytic lineage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1262.jpg" -"1263" "What cytoplasmic feature can be observed in the blast cells featured in the main image?" "Eosinophilic cytoplasm" "Basophilic cytoplasm" "Scanty cytoplasm" "Abundant cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1263.jpg" -"1264" "What nuclear feature is indicative of active cellular processes in the large blasts seen in the image?" "Condensed chromatin" "Pyknotic nuclei" "Multiple nucleoli" "Opened-up chromatin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1264.jpg" -"1265" "Based on the cellular morphology observed in the image, what is the predominant nuclear shape?" "Predominantly spindle-shaped" "Predominantly round" "Predominantly oval" "A mix of round, oval, and irregularly shaped" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1265.jpg" -"1266" "What is the predominant cell type visible in this histological image?" "Columnar epithelial cells" "Round lymphocytes" "Spindle-shaped mesenchymal cells" "Cuboidal epithelial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1266.jpg" -"1267" "By closely observing the organization of the cells within the stroma, what can be inferred about the potential nature of the tissue?" "The stroma suggests a myxoid matrix due to its pale, bluish appearance" "The tissue displays mild anaplasia with some cellular organization" "The tissue exhibits a high degree of organization typical of normal tissue" "The cellular arrangement indicates a well-differentiated neoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1267.jpg" -"1268" "What does the staining pattern in the image indicate about the nuclei of the spindle cells?" "The nuclei are small and inconspicuous with no visible nucleoli" "The nuclei are pleomorphic and exhibit significant variation in size" "The nuclei are elongated, suggesting a mesenchymal origin" "The nuclei are hyperchromatic indicating high DNA content" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1268.jpg" -"1269" "The appearance of swollen endothelial cells and the presence of pinkish hue in some areas most likely indicate:" "Evidence of blood congestion within the capillaries" "Artifacts from the tissue preparation process" "Alterations in the glomerular basement membrane and mesangial matrix" "Normal variation in capillary wall thickness" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1269.jpg" -"1270" "Based on the glomerular morphology observed in the image, what characteristic best describes the glomerulus?" "Fibrotic with significant sclerosis" "Hypercellular with obscured capillary lumens" "Normal cellularity with distinct capillary loops" "Hypocellular with evidence of crescent formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1270.jpg" -"1271" "Which cellular characteristic is indicated by the black arrows?" "Prominent nucleoli" "Binucleation" "Pyknotic nuclei" "Hyperchromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1271.jpg" -"1272" "What pathological feature do the asterisks (*) indicate?" "Inflammatory cell infiltration" "Perivascular cuffing" "Neuritic plaques" "Blood vessels" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1272.jpg" -"1273" "After applying a specific staining technique to this tissue sample, the presence of what type of cell wall component can be inferred from the reddish-purple color of the bacteria?" "Lipopolysaccharide" "Mycolic acid" "Teichoic acid" "Peptidoglycan" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1273.jpg" -"1274" "What feature is the arrow pointing to in the given microscopic image?" "A keratin pearl" "Normal glandular architecture" "An area of coagulative necrosis" "A mitotic figure" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1274.jpg" -"1275" "What does the overall morphology of the cells within the dense cellular regions suggest?" "Dysplasia" "Metaplasia" "Inflammatory infiltration" "Benign hyperplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1275.jpg" -"1276" "What staining characteristics of the smaller, dark-staining cells in the image suggest about their identity?" "Neutrophil multilobed nuclei" "Lymphocyte nuclei" "Plasma cell cytoplasm" "Eosinophil granules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1276.jpg" -"1277" "Analyzing the elongated, wavy structures in the image, what type of tissue component are these structures likely to represent?" "Elastic fibers" "Muscle fibers" "Nerve fibers" "Collagen fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1277.jpg" -"1278" "What is the nature of the cellular aggregation observed in the center of the glandular structures?" "Crypt abscesses" "Keratin pearls" "Schiller-Duval bodies" "Granuloma formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1278.jpg" -"1279" "The nuclei of certain cells in the image stain dark blue-purple with hematoxylin. What is the best description of the morphology of these nuclei?" "Multi-lobed nuclei" "Large, round nuclei with prominent nucleoli" "Multiple small, uniform nuclei" "Hyperchromatic with coarse chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1279.jpg" -"1280" "In the region pointed to by the arrow, what could be the possible interpretation of a cluster of cells with a high nuclear to cytoplasmic ratio and prominent nucleoli?" "Increased cellular activity or inflammatory infiltrate" "Evidence of squamous metaplasia within the epithelial cells" "Normal cellular maturation as the cells move toward the surface" "Fibroblastic proliferation within the stroma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1280.jpg" -"1281" "Based on the image of the liver tissue, what does the open fat arrow (hollow, thick) indicate?" "Interface hepatitis with lymphocytic infiltration" "Presence of a leukocyte within a hepatocyte" "Endothelial lifting in a portal venule" "An eosinophilic leukocyte in the sinusoidal space" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1281.jpg" -"1282" "In the provided image of liver tissue, what cellular feature does the solid arrow identify?" "A lymphocyte within the bile duct epithelium" "A hepatocyte undergoing apoptosis" "A rare eosinophilic leukocyte" "A macrophage engulfing foreign material" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1282.jpg" -"1283" "What does the white arrow in the image of the liver tissue point to?" "Cellular steatosis" "Endothelial lifting in a portal venule" "Kupffer cell activation" "Hepatocyte regeneration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1283.jpg" -"1284" "Based on the morphology observed in the tissue, which cell type is indicated by the black long arrow and is found along the periphery of the seminiferous tubules?" "Spermatid" "Spermatocyte" "Sertoli cell" "Spermatogonium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1284.jpg" -"1285" "Comparing zones '1', '2', and '3', which zone shows the least density of reticulin fibers?" "Zone '3'" "The density is the same in all zones" "Zone '1'" "Zone '2'" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1285.jpg" -"1286" "What is the histological appearance of the central vein labeled 'V' with respect to the surrounding reticulin fiber network?" "The reticulin fibers around the central vein form a tight mesh, similar to the portal tract" "There is a distinct lack of reticulin fibers around the central vein" "The central vein displays a dense reticulin network similar to zone '1'" "The central vein shows reticulin fibers that are more loosely arranged than in other zones" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1286.jpg" -"1287" "What is the appearance of the red blood cells surrounding the ones with intracellular inclusions?" "They appear as target cells with a bullseye appearance" "They show evidence of significant agglutination" "They possess obvious spicules around the cell membrane" "They display a prominent central pallor with a biconcave disk shape" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1287.jpg" -"1288" "Analyzing the nuclear characteristics of the cells in the image, what can be inferred?" "Nuclei appear small and uniform" "Nuclei are predominantly round and centrally located" "Nuclei exhibit pronounced nucleoli" "Nuclei show signs of hyperchromasia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1288.jpg" -"1289" "What additional pathological feature can be identified in the fibrous connective tissue stroma within this image?" "Neutrophil infiltration" "Necrotic cell debris" "Lymphatic vessel proliferation" "Extravasated red blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1289.jpg" -"1290" "What is the predominant staining pattern observed in the cytoplasm of the cells within the tissue?" "Pinkish to tan with strong brownish areas" "Light blue with scattered red granules" "Uniformly dark purple" "Green with yellowish speckles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1290.jpg" -"1291" "How would you characterize the visible structures that resemble blood vessels?" "They appear as compact structures with multilayered cell walls" "Their lumens are clear and unstained surrounded by supportive tissue" "They are composed of densely packed eosinophilic cells" "They display dark purple staining within their lumens" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1291.jpg" -"1292" "What can be inferred about the orientation and arrangement of cells in this tissue sample?" "Cells have a columnar epithelial orientation" "Cells demonstrate an interwoven or spindle-shaped arrangement" "Cells are arranged in a glandular pattern" "Cells are dispersed with no particular arrangement" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1292.jpg" -"1293" "Based on the presence of the granular black pigment indicated by the white arrow, which of the following pigments is most consistent with this appearance?" "Hemosiderin" "Melanin" "Anthracosis" "Lipofuscin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1293.jpg" -"1294" "Where can syncytial cells be observed in the provided image?" "Throughout the epithelial layers containing eosinophilic intranuclear inclusion bodies" "Within the stratified squamous epithelium on the left side" "At the surface of the epithelium where there is amorphous, eosinophilic debris" "Within the dense neutrophilic infiltrate on the right side" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1294.jpg" -"1295" "What histological feature does the arrow markers most likely indicate in this image?" "Inflammatory cell infiltration" "Vascular proliferation" "Myxoid degeneration" "Neoplastic cell clusters" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1295.jpg" -"1296" "In the upper image (a), what is the predominant pattern demonstrated by the intense brown staining after immunohistochemical (IHC) staining?" "Focal cytoplasmic aggregation" "Membrane and cytoplasmic localization" "Nuclear localization" "Extracellular matrix staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1296.jpg" -"1297" "Which of the following features does NOT describe the overall architecture of the tissue seen in the image?" "Disordered arrangement" "An organized, structured layout" "Atypical mitotic figures" "Pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1297.jpg" -"1298" "What cellular differentiation feature can be identified based on the presence of specific material in the tissue?" "Myogenic differentiation with cross-striations" "Epithelial differentiation with keratinizing material" "Neural differentiation with neurofibrillary material" "Lipogenic differentiation with clear vacuoles" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1298.jpg" -"1299" "Identify the structure at the center of the image outlined by a layer of pink endothelial cells." "Blood vessel" "Lymphoid nodule" "Hassall's corpuscle" "Thymic corpuscle" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1299.jpg" -"1300" "From the coloration in the image provided, which staining technique is suggested to have been used for this histological section?" "Toluidine blue stain" "Periodic acid–Schiff stain" "Masson's trichrome stain" "Hematoxylin and eosin stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1300.jpg" -"1301" "Considering the overall arrangement of the cells, which option is not consistent with standard tissue organization?" "Lack of a uniform pattern" "Presence of clear boundaries in some cells" "Closely packed cell population" "Neatly organized rows of cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1301.jpg" -"1302" "Based on the chromogranin A immunostaining pattern, what is the predominant cellular population in this tissue section?" "Neuroendocrine cells" "Muscle cells" "Lymphocytes" "Epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1302.jpg" -"1303" "Judging by the arrangement of the tissue and cell types observed, what is the most likely origin of this sample?" "Connective tissue" "Muscular tissue" "Glandular tissue" "Neural tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1303.jpg" -"1304" "What can be inferred about the mitotic activity in this tissue sample?" "Numerous typical mitotic figures in the basal layer only, reflecting controlled proliferation" "Mitotic figures are absent, indicating low mitotic activity" "Atypical mitotic figures are present, suggesting increased and abnormal mitotic activity" "Normal mitotic figures are uniformly distributed, implying a well-regulated cell cycle" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1304.jpg" -"1305" "Based on the staining characteristics observed, what is the likely staining technique used in this microscopic image?" "Hematoxylin and eosin (H&E)" "Modified Wright-Giemsa" "Acridine orange" "Papanicolaou stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1305.jpg" -"1306" "Considering the interstitial component of this renal tissue, what is the most likely pathological feature indicated by the pale pink-stained areas?" "Lymphocytic infiltration" "Interstitial fibrosis" "Interstitial edema" "Granulomatous inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1306.jpg" -"1307" "Based on the appearance of the extracellular matrix, what type of tissue characterizes the non-adipose areas of the image?" "Myxoid tissue" "Osteoid tissue" "Fibrous connective tissue" "Cartilaginous tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1307.jpg" -"1308" "What architectural feature can be observed in the glandular duct-like structures within the tissue?" "Regularly spaced ductal cells with consistent shapes" "Aberrant architecture with irregular duct-like structures" "Duct-like structures with a concentric arrangement" "Uniform ductal cells with well-defined lumens" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1308.jpg" -"1309" "The cytoplasm of the cells in the image has stained which color, indicating the nature of the cells?" "Basophilic (blue to purple)" "Eosinophilic (pinkish-red)" "Neutrophilic (pale pink to purple)" "Amphiphilic (mixed staining)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1309.jpg" -"1310" "Which description best matches the cytoplasmic staining observed in the cells in the image?" "Abundant eosinophilic cytoplasm" "Sparse basophilic cytoplasm" "Clear, non-staining cytoplasm" "Homogeneously pale-staining cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1310.jpg" -"1311" "Which of the following features best describes the mucosal architecture observed in the image of the ileal tissue?" "Presence of prominent finger-like villi" "Villous blunting and loss" "Atrophy of the villi with flattened epithelial cells" "Hyperplasia of the crypts" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1311.jpg" -"1312" "What can be concluded about the inflammatory response in the ileal tissue based on the infiltrating cells observed?" "There is a significant accumulation of infiltrating cells indicative of chronic inflammation" "There is a heavy polymorphonuclear infiltrate indicative of acute inflammation" "There is a mild inflammatory infiltrate within the chorion" "No infiltrating cells are present, suggesting a lack of inflammatory response" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1312.jpg" -"1313" "Analyzing the image, what distinguishes the entrapped structures in the hyalinized area from the surrounding tissue?" "The entrapped structures are more basophilic due to nuclear staining" "The entrapped structures are more eosinophilic than the matrix" "The matrix is more basophilic than the entrapped structures" "The entrapped structures lack discernible cell boundaries" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1313.jpg" -"1314" "Based on the histological features observed in the image, which pattern is most characteristic of the spindle-shaped cells?" "Concentrically arranged in a whorled pattern" "Linearly aligned parallel to each other" "Randomly scattered without a distinct pattern" "Isolated in clusters apart from the extracellular matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1314.jpg" -"1315" "Based on the metachromatic features observed in the microscopic field, which of the following stains was most likely used?" "Hematoxylin and eosin (H&E)" "Giemsa stain" "Periodic acid–Schiff (PAS) stain" "Acid-Fast Bacilli (AFB) stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1315.jpg" -"1316" "In this microscopic view of lung tissue, what cell characteristic is observed within the small airway wall?" "Presence of goblet cells" "Ciliated columnar epithelial cells" "Clusters of adipocytes" "Multinucleated giant cells lining the airway" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1316.jpg" -"1317" "What can be inferred about the non-neuroendocrine cells in the lung tissue?" "They exhibit prominent nucleoli" "They have nuclei that are dense and stain blue" "They are stained brown due to the expression of neuroendocrine markers" "They contain secretory granules in the cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1317.jpg" -"1318" "What best characterizes the pattern of cellular infiltration seen in the superficial dermis?" "Uniformly dispersed throughout the dermis" "Nodular pattern within diffuse infiltrate" "Predominantly perivascular" "Concentrated around adnexal structures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1318.jpg" -"1319" "Which observation would be consistent with a pattern suggestive of vascular congestion within this tissue sample?" "Regions with homogeneously distributed eosinophilic cytoplasm" "Regions showing multinucleated giant cells" "Regions more densely populated by cells" "Regions that have fewer cells and more abundant extracellular matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1319.jpg" -"1320" "Based on the density and organization of the cells, what can be inferred about the tissue's cellular matrix?" "Predominantly acellular with abundant extracellular matrix" "Highly cellular with minimal extracellular matrix" "Balanced ratio of cellular to extracellular matrix components" "Fibrotic with collagenous bands separating cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1320.jpg" -"1321" "What morphologic feature is most prominent within the glomerulus in this renal biopsy specimen?" "Synechiae formation between the Bowman's capsule and the glomerulus" "Extensive podocyte effacement" "Glomerulosclerosis with hyalinosis" "Fibrocellular crescent involving the Bowman's space" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1321.jpg" -"1322" "What observation in the image may suggest variations in the fiber content or a response to an injury?" "Areas where the staining is lighter" "Uniform size and shape of muscle fibers" "Presence of a bar for scale" "Areas with darker staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1322.jpg" -"1323" "Based on the cytoplasmic staining observed in the microscopic image, which specific cellular protein or enzyme is most likely being indicated by the immunohistochemical stain?" "Myoglobin" "Hemoglobin" "CD20" "Actin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1323.jpg" -"1324" "In this tissue section, how does the distribution of staining intensity across the nuclei and cytoplasm help differentiate between a benign and malignant process?" "Staining absent in the nuclei" "Uniform staining intensity" "Variable staining intensity" "Staining only in the perinuclear region" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1324.jpg" -"1325" "Observing the gradient in staining intensity from the bottom to the top, what can be inferred about the density and composition of the tissue?" "Uniform density and composition throughout the tissue" "Higher cellular density with diminished extracellular matrix at the bottom" "Increasing density and extracellular matrix deposition towards the bottom" "Lower cellular density with abundant hyaline material at the top" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1325.jpg" -"1326" "Identify the area of hyperplasia in the tissue specimen." "Area away from the arrows and asterisk" "Area near the thick arrow" "Area near the fine arrow" "Area indicated with an asterisk (*)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1326.jpg" -"1327" "Where is the marked edema likely located in this specimen?" "In the area where the thick arrow is pointing" "In the area where the fine arrow is pointing" "In the area indicated with an asterisk (*)" "In areas not indicated by any arrow or symbol" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1327.jpg" -"1328" "What cellular alteration is the thick arrow most likely indicating in this image?" "Dilated capillaries" "Necrotic tissue" "Inflammatory cell infiltration" "Neoplastic transformation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1328.jpg" -"1329" "What architectural pattern do the glandular structures within the lesion exhibit in this microscopic image?" "Branched or lobulated" "Irregular and infiltrative" "Nested with confluence" "Papillary with fibrovascular cores" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1329.jpg" -"1330" "What is the morphology of the nuclei in the predominant cell type, suggesting epithelioid cells?" "Elongated, oval to spindle-shaped nuclei" "Hyperchromatic and irregular nuclei" "Round nuclei with prominent nucleoli" "Small, hyperchromatic nuclei with scant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1330.jpg" -"1331" "Based on the immunohistochemical staining, what is the most likely antigen distribution in the observed cells?" "Membranous" "Nucleolar" "Cytoplasmic" "Nuclear" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1331.jpg" -"1332" "When examining the nuclear features of the cells, what detail supports the pathological nature of the tissue?" "The presence of small, uniform nucleoli" "The finely granular chromatin pattern" "The round to oval shape of the nuclei" "The absence of nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1332.jpg" -"1333" "What does the structure on the right side of the image predominantly consist of?" "Dense regular connective tissue" "Fibrocartilage tissue" "Loose connective tissue" "Muscle tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1333.jpg" -"1334" "When observing the nuclear characteristics in the cells highlighted by the arrows, what is a defining feature visible in these cells?" "Hypersegmented nuclei" "Monotonous cell population with anisonucleosis" "Fine and dispersed nuclear chromatin" "Coarse clumping of nuclear chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1334.jpg" -"1335" "In the first section (a), what is the dominant staining characteristic of the tumor cells' cytoplasm?" "Eosinophilic (pink-staining) with abundant cytoplasm" "Basophilic (blue-staining) with sparse cytoplasm" "Eosinophilic (pink-staining) with sparse cytoplasm" "Basophilic (blue-staining) with abundant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1335.jpg" -"1336" "In section (b), what is the nature of the cellular architecture of the smaller cells shown?" "Dyscohesive sheets of cells with poorly defined borders" "Cohesive sheets of cells with poorly defined borders" "Cohesive sheets of cells with well-defined borders" "Dyscohesive clusters of cells with well-defined borders" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1336.jpg" -"1337" "What is the pattern of nuclear chromatin distribution observed in the cells of the third section (c)?" "Finely granular with normochromasia" "Coarsely granular with hyperchromasia" "Finely granular with hyperchromasia" "Raisinoid with hyperchromasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1337.jpg" -"1338" "Based on the morphology of the multinucleated giant cells indicated by arrows, what is the likely nature of these cells?" "Foreign body-type giant cells" "Langhans-type giant cells" "Osteoclast-like cells" "Touton-type giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1338.jpg" -"1339" "Observing the cytoplasm of the multinucleated giant cells, what characteristic is noted?" "The cytoplasm appears eosinophilic" "The cytoplasm exhibits melanin pigmentation" "The cytoplasm appears clear and vacuolated" "The cytoplasm contains numerous lipid droplets" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1339.jpg" -"1340" "Based on the tissue morphology seen in the image, which option is least likely to describe the nature of the observed tissue process?" "Chronic inflammation" "Benign neoplasm" "Malignant neoplasm" "Acute inflammation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1340.jpg" -"1341" "What cellular feature is consistent with the appearance of the cells within the lumen of the central blood vessel?" "Neutrophil extracellular traps (NETs)" "Hyperchromatic nuclei" "Crenated red blood cells" "Cells with foamy cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1341.jpg" -"1342" "What feature best describes the nuclei of the spindle-shaped cells in this tissue section?" "Uniformly distributed chromatin with occasional prominent nucleoli" "Vesicular chromatin with frequent mitotic figures" "Mild pleomorphism with inconspicuous nucleoli" "Hyperchromatic with irregular nuclear borders" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1342.jpg" -"1343" "Based on the morphological features observed in this tissue section, which category of cells appears to be interspersed among the spindle-shaped cells?" "Histiocytic cells with indented nuclei and eosinophilic cytoplasm" "Lymphocytes with a small round morphology and dense chromatin" "Neutrophils with multi-lobed nuclei and pale cytoplasm" "Epithelioid cells with abundant cytoplasm and distinct cell boundaries" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1343.jpg" -"1344" "What is the predominant pattern of the glands observed in the tissue?" "Rosette-like pattern" "Trabecular pattern" "Lobular pattern" "Cribiform pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1344.jpg" -"1345" "What feature of the extracellular matrix is apparent in this hematoxylin and eosin (H&E) stained image?" "Necrotic extracellular matrix" "Eosinophilic extracellular matrix" "Calcified extracellular matrix" "Myxoid extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1345.jpg" -"1346" "What alterations can be observed in the fundic glands of this gastric tissue sample?" "Disruption of glandular structure" "Preservation of normal glandular architecture" "Atrophy of glandular cells" "Hyperplasia of glandular cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1346.jpg" -"1347" "What does the brown staining in the cytoplasm of the cells indicate?" "Accumulation of glycogen" "Absence of nucleic acids" "Presence of the Epidermal Growth Factor Receptor (EGFR)" "Presence of lipofuscin pigment" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1347.jpg" -"1348" "Based on the arrangement of the nuclei within the epithelial cells lining the cyst wall, how would you classify the epithelium?" "Simple columnar epithelium" "Stratified squamous epithelium" "Simple squamous epithelium" "Stratified columnar epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1348.jpg" -"1349" "What is the nature of the acellular material present within the cyst as observed in the image?" "Keratin" "Mucin" "Collagen" "Elastin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1349.jpg" -"1350" "What is the predominant cell type observed in this histological image of the tissue?" "Spindle cells" "Columnar epithelial cells" "Adipocytes" "Squamous epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1350.jpg" -"1351" "Based on the cellular morphology and arrangement, which diagnostic consideration is supported by this image?" "Healthy bone tissue" "Lipoma" "Osteosarcoma" "Chondrosarcoma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1351.jpg" -"1352" "What structural feature is prominently displayed by the cells in this histopathological specimen?" "Hollow tubules with a single layer of flat cells" "Multilayered stratification" "Elongated cells forming papillary projections" "Small, round and clustered formations" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1352.jpg" -"1353" "What can be inferred about the keratinocytes in the epidermal layer of this skin tissue sample?" "They exhibit hyperkeratosis characterized by a thickened stratum corneum" "They are undergoing abnormal mitotic figures consistent with dysplasia" "They appear as multinucleated giant cells indicative of a viral infection" "They show signs of necrosis including increased eosinophilia and nuclear changes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1353.jpg" -"1354" "What is the predominant cell type visible in the connective tissue matrix of this high-power H&E stained histological section?" "Chondrocytes" "Schwann cells" "Fibroblasts" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1354.jpg" -"1355" "Which of the following features best supports the identification of the eosinophilic matrix in this tissue section?" "Marked basophilic stippling" "Variability in the density and arrangement of collagen fibers" "Periodic acid-Schiff reactivity" "Alcian blue positivity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1355.jpg" -"1356" "What type of cells show a large amount with ample cytoplasm, as seen under the microscope in this renal tissue section?" "Fibroblasts" "Plasma cells" "Macrophages" "Tubular epithelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1356.jpg" -"1357" "Which cell type can be identified by eosinophilic cytoplasm and bi-lobed nuclei in this histologic image of renal tissue?" "Mast cells" "Eosinophils" "Neutrophils" "Basophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1357.jpg" -"1358" "What pattern of fibrosis is best exemplified by the arrangement of collagen fibers in this image of renal tissue?" "Diffuse pattern fibrosis" "Nodular pattern fibrosis" "Linear pattern fibrosis" "Storiform pattern fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1358.jpg" -"1359" "Based on the morphology of the epithelial cells lining the duct-like structures, what type of epithelium is present?" "Simple cuboidal epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Simple columnar epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1359.jpg" -"1360" "Which type of cell in the image has a condensed chromatin pattern with indented or folded nuclei, which might suggest a stage of differentiation from the blast stage?" "Myeloblasts" "Eosinophils" "Basophils" "Promonocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1360.jpg" -"1361" "Which layer of the epidermis shows the most significant thickening in the provided image?" "Stratum corneum" "Stratum basale" "Stratum spinosum" "Stratum granulosum" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1361.jpg" -"1362" "What cellular morphology is evident in the epidermal keratinocytes in this image?" "Malignant transformation" "Necrotic cell death" "Apoptotic bodies" "Viral cytopathic effect" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1362.jpg" -"1363" "Based on the staining characteristics of the tissue section, which staining technique is most likely to have been used?" "Acid-fast bacilli (AFB) stain" "Periodic acid-Schiff (PAS) stain" "Hematoxylin and Eosin (H&E) stain" "Gomori methenamine silver (GMS) stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1363.jpg" -"1364" "What does the appearance of the extracellular matrix in this tissue section suggest?" "There is little extracellular matrix visible" "The presence of abundant extracellular matrix" "The tissue is highly fibrotic" "The extracellular matrix is evenly distributed" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1364.jpg" -"1365" "How would you categorize the level of cellularity in this tissue section?" "Hypercellularity with severe crowding" "Moderate cellularity with some separation between cells" "Low cellularity with generous extracellular matrix" "High cellularity with overlapping cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1365.jpg" -"1366" "Based on the cellular morphology observed in the image, what is a prominent characteristic of the larger cells?" "Small, condensed nuclei" "Clear cytoplasm" "Hyperchromatic nuclei" "Dark, eosinophilic cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1366.jpg" -"1367" "What can be inferred about the tissue architecture from the image?" "Perfectly normal tissue architecture" "Organized with some areas of disarray" "Well-organized with distinct layering" "Largely disorganized with loss of normal structure" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1367.jpg" -"1368" "What feature in the image indicates the presence of a chronic inflammatory process?" "The large cells with multinucleated appearances" "The homogenous appearance of the cellular distribution" "The small, densely stained cells with scant cytoplasm" "The large cells with abundant pink cytoplasm and central nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1368.jpg" -"1369" "Based on the cellular morphology present, what is the likely nature of the proliferative activity observed in the tissue?" "Proliferation of adipocytes in response to injury" "Formation of granulation tissue with fibroblasts" "Neoplastic growth of epithelial cells" "Accumulation of mature collagen fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1369.jpg" -"1370" "What conclusion can be drawn about the foamy cytoplasmic cells observed throughout the tissue?" "They suggest the tissue is undergoing lipomatous metaplasia" "They indicate the presence of mature adipocytes" "They are likely histiocytes involved in an immune response" "They are indicative of skeletal muscle regeneration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1370.jpg" -"1371" "How would you describe the cytoplasmic amount in the cells shown in this immunohistochemical staining for CD45?" "Abundant" "Scant" "Moderate" "Indistinguishable" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1371.jpg" -"1372" "Based on the morphological features, which cellular characteristic is NOT evident in this image?" "Cohesiveness among the epithelial cells" "High degree of nuclear pleomorphism" "Basophilic staining of the cytoplasm" "Uniformity in the distribution of hyperchromatic nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1372.jpg" -"1373" "Based on the microscopic features observed in the image, what type of necrosis is predominantly seen at the center of the tissue section marked by the arrow?" "Fibrinoid necrosis" "Fat necrosis" "Caseous necrosis" "Coagulative necrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1373.jpg" -"1374" "The granulomatous reaction visualized in the tissue section given, with central necrosis surrounded by a nodular arrangement of mononuclear cells, most closely suggests which of the following pathological conditions?" "Bacterial abscess" "Tuberculosis" "Sarcoidosis" "Rheumatoid nodule" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1374.jpg" -"1375" "Considering the outer regions of the tissue section that display a structured cellular arrangement, which cell types would you expect to be predominantly present in a native, healthy issue of this type?" "Keratinocytes and melanocytes" "Hepatocytes and sinusoids" "Neurons and glial cells" "Squamous epithelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1375.jpg" -"1376" "What morphological feature of adipocytes is typically altered due to the histological processing of the tissue specimen?" "Nucleus displacement to the center of the cell" "Absence of visible stored fat within the cells" "Increased eosinophilia of the cytoplasm" "Cytoplasmic enlargement and vacuolization" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1376.jpg" -"1377" "Based on the tissue morphology, what is the most prominent feature evident in the stroma between the adipocytes?" "Sparse cellular composition" "Atypical lymphocyte infiltration" "Well-organized fibrous architecture" "Homogeneous cell distribution" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1377.jpg" -"1378" "Observing the nuclei of the spindle-shaped cells at higher magnification, what is the most accurate description of their appearance?" "Hyperchromatic and irregularly shaped" "Large and pleomorphic" "Small with prominent nucleoli" "Small and uniform without prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1378.jpg" -"1379" "In relation to the cellularity of the examined tissue, what feature stands out in the background?" "Myxoid matrix" "Abundant collagenous stroma" "Significant inflammatory infiltrate" "Abundant adipose tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1379.jpg" -"1380" "Based on the endothelial lining of the hepatic sinusoids, what condition could be suggested?" "Sinusoidal congestion" "Atrophy of endothelial cells" "Endothelial hyperplasia" "Endothelial disarray" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1380.jpg" -"1381" "Based on the immunohistochemical staining pattern, which membranous protein is likely being targeted by the antibody used in this image?" "CD99" "Cytokeratin" "CD20" "Vimentin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1381.jpg" -"1382" "How would you characterize the cellular arrangement observed in the tissue specimen?" "Uniform and well-organized" "Loosely arranged with abundant extracellular matrix" "Sparsely distributed and regular" "Dense and irregular" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1382.jpg" -"1383" "What is the nature of the cytoplasm observed in the cells of this tissue specimen?" "Abundant and basophilic" "Abundant and eosinophilic" "Vacuolated with clear spaces" "Scant and not clearly visible" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1383.jpg" -"1384" "Based on the cellular morphology observed under the microscope, which of the following characteristics are most consistent with the cells in the lamina propria?" "Large cells with abundant eosinophilic granular cytoplasm" "Spindle-shaped cells with scarce cytoplasm" "Multinucleated giant cells with peripheral nuclei" "Small round cells with high nuclear to cytoplasmic ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1384.jpg" -"1385" "Within the field of view, which observation regarding proliferative activity could be made?" "Extensive areas of necrosis implying uncontrolled cell death" "There is a high mitotic index indicative of active proliferation" "Numerous apoptotic bodies present suggesting high cell turnover" "No evidence of mitotic figures, indicating a lack of active proliferation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1385.jpg" -"1386" "Based on the histological features present, what is the likely diagnosis?" "Ewing's sarcoma" "Osteosarcoma" "Chondrosarcoma" "Fibrosarcoma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1386.jpg" -"1387" "What feature is characteristic of the epidermal changes observed in this skin biopsy?" "Parakeratosis" "Clear cell change" "Acantholysis" "Dyskeratosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1387.jpg" -"1388" "In regards to the lesion's distribution and localization on the skin biopsy, which observation is most consistent with the findings?" "Pathologic changes are uniform throughout the biopsy" "The perimeter of the biopsy displays the greatest pathology" "The center portion of the lesion shows pathologic changes" "The lesion extends across the entire width of the biopsy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1388.jpg" -"1389" "In analyzing the cytoplasmic characteristics of these cells, what is the predominant staining quality observed?" "Cytoplasm showing metachromatic reaction" "Homogeneous cytoplasm with clear perinuclear halo" "Basophilic cytoplasm with patches of eosinophilia" "Eosinophilic cytoplasm throughout" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1389.jpg" -"1390" "Considering the staining properties of the tissue, what is the predominant feature of the stroma as it appears in this H&E stained section?" "Predominantly basophilic with a fibrous texture" "Mixed eosinophilic and basophilic with high cellularity" "Intensely eosinophilic with numerous inflammatory cells" "Eosinophilic with a glassy, acellular appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1390.jpg" -"1391" "What can be inferred about the cellular architecture based on the clusters of cells with round basophilic nuclei within the stroma?" "Architectural uniformity indicates a well-differentiated tissue" "The architecture suggests high-grade dysplasia with pleomorphism" "There is evidence of significant neoplastic infiltration" "The presence of multi-nucleated giant cells indicates granulomatous inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1391.jpg" -"1392" "What feature is indicated by the circled area that is notable for having a dense collection of cells?" "Melanocytic nevus" "Lymphocytic infiltration" "Granulomatous inflammation" "Neutrophilic infiltration" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1392.jpg" -"1393" "What is indicated by the asterisk in the epidermis?" "Hypergranulosis" "Basal cell hyperplasia" "Acantholysis" "Pallor of the spinous layer" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1393.jpg" -"1394" "Based on the features displayed in the image, what pathology is most likely represented?" "Lichen planus" "Psoriasis" "Atopic dermatitis" "Seborrheic dermatitis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1394.jpg" -"1395" "What is the nature of the cell nuclei in the myoepithelial cells as observed in the image?" "The nuclei are hyperchromatic and vary in size" "The nuclei are swollen with a clear perinuclear halo" "The nuclei contain multiple nucleoli and are irregular in shape" "The nuclei are not readily distinguishable due to the intense cytoplasmic staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1395.jpg" -"1396" "How would you characterize the overall tissue architecture observed?" "Well-organized and differentiated with a clear demarcation between the stained and unstained regions" "Lacking structural integrity with widespread necrosis" "Disorganized with a loss of differentiation" "Showing signs of cellular atypia and malignant transformation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1396.jpg" -"1397" "What is the predominant feature of the cells present in the nests?" "Well-defined cell borders" "Hyperchromatic nuclei" "Abundant cytoplasm" "Clear cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1397.jpg" -"1398" "Observing the chromatin pattern within the cell nuclei, which description best fits?" "Presenting as large nucleoli" "Hyperchromatic with irregular distribution" "Coarse and clumped" "Fine and homogenous" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1398.jpg" -"1399" "Assessing the degree of pleomorphism in the cells, which statement is accurate?" "Cells are anaplastic with complete loss of normal features" "Minimal variation in the size and shape of cells" "Moderate pleomorphism with some variation in size and shape" "High degree of pleomorphism with marked variation in cell size and shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1399.jpg" -"1400" "What pattern is predominantly exhibited by the clusters of cells in the image?" "Nesting growth pattern" "Syncytial growth pattern" "Dispersed single cell pattern" "Cribriform pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1400.jpg" -"1401" "Based on the staining characteristics in this image, which protein expression is most likely highlighted by the brown pigmentation of certain cells?" "Keratin protein expression" "S100 protein expression" "CD34 protein expression" "Estrogen receptor protein expression" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1401.jpg" -"1402" "Which type of tissue, indicated by the presence of spindle-shaped cells with eosinophilic cytoplasm, is depicted in the microscopic image?" "Epithelial tissue" "Connective tissue" "Muscle tissue" "Neural tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1402.jpg" -"1403" "In this image, what is the predominant staining color of the medium in which the cells are suspended?" "Green to yellow" "Red to orange" "Blue to dark purple" "Light to pinkish" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1403.jpg" -"1404" "What feature in the image most accurately differentiates lymphocytes from the identified microfilariae?" "Presence of a large central vacuole" "A tail-like projection extending from the cell body" "Multiple, segmented nuclei" "Darkly stained nuclei with a surrounding halo" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1404.jpg" -"1405" "In the context of the given tissue section, what could the variably sized clear spaces represent?" "Adipocytes typical of subcutaneous tissue" "Artifacts from the tissue processing" "Areas of necrosis" "Lymphatic spaces" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1405.jpg" -"1406" "What does the branching and filamentous morphology of the structures in the image suggest about their possible identity?" "Typical leukocyte cellular debris due to presence amongst other cells" "Fungal hyphae due to branching" "Non-filamentous bacterial clusters due to red coloration" "Partially acid-fast bacilli due to staining and morphology" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1406.jpg" -"1407" "Based on the microscopic features observed, what is the likely nature of the circular profiles with darkly stained outlines?" "Benign gastric epithelial cells" "Adenocarcinoma cells" "Normal gastric pit cells" "Cross-section of parasitic tunnels" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1407.jpg" -"1408" "What change in the tissue can be deduced from the presence of cells with a high nucleus-to-cytoplasm ratio around the glandular structure?" "Metaplastic transformation" "Neoplastic proliferation" "Inflammatory infiltration" "Dysplastic growth" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1408.jpg" -"1409" "What is the predominant staining characteristic of the nuclei in the large foamy cells observed in the lamina propria?" "Neutrophilic" "Basophilic" "Eosinophilic" "Amphophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1409.jpg" -"1410" "How would you describe the distribution of the large foamy cells within the lamina propria?" "Uniformly distributed" "Arranged in a linear pattern" "Loosely distributed" "Clustered and tightly packed" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1410.jpg" -"1411" "What is the predominant architectural pattern exhibited by the neoplastic cells in this image?" "Solid sheets" "Acinar structures" "Ductal formations" "Nested/trabecular" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1411.jpg" -"1412" "Based on the image, how would you describe the appearance of the nuclei of the neoplastic cells?" "Hyperchromatic with prominent nucleoli" "Smudged chromatin with indistinct nuclear membranes" "Highly pleomorphic with coarse chromatin" "Relatively uniform with fine chromatin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1412.jpg" -"1413" "Based on the tissue morphology visible in the image, which of the following best describes the lining of the vascular channels?" "Thick muscular wall structure surrounding the spaces" "Endothelial lining with prominent nuclei" "Hyperplastic endothelium with multiple layers" "Extremely thin, almost imperceptible endothelial lining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1413.jpg" -"1414" "Looking at the cellular composition in the connective tissue, what type of cells predominate between the vascular spaces?" "Smooth muscle cells in a whorled pattern" "Skeletal muscle cells with striations" "Inflammatory cells scattered within fibrous connective tissue" "Adipocytes with large vacuoles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1414.jpg" -"1415" "What can be inferred about the overall cellular composition of this tissue section based on the staining pattern?" "The tissue mainly consists of nervous tissue" "The tissue consists mostly of muscle fibers" "There is a high density of immune cells in the tissue" "The tissue is predominantly composed of adipocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1415.jpg" -"1416" "What is the architectural pattern observed in the epithelial component of the lesion?" "Plexiform pattern" "Nesting and trabecular pattern" "Corded and lobular pattern" "Acinar and microcystic pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1416.jpg" -"1417" "What observation from the image supports the lack of typical bone marrow architecture?" "Presence of numerous fat cells" "Uniform appearance of cell types" "High cellular density making the architecture difficult to decipher" "Low density of cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1417.jpg" -"1418" "What histological feature is indicated by the arrows in the given image?" "Glomerular enlargement" "Tubular atrophy" "Intertubular congestion" "Inflammatory infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1418.jpg" -"1419" "Judging by the staining pattern, what cytoplasmic characteristic can be observed in the majority of the cells?" "Eosinophilic cytoplasm" "Foamy cytoplasm" "Clear cytoplasm" "Basophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1419.jpg" -"1420" "Assessing the cellular morphology in the bone marrow biopsy image, which type of cells can be predominantly observed based on their distinctive staining and morphology?" "Lymphocytes" "Myeloid precursors" "Erythroid precursors" "Megakaryocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1420.jpg" -"1421" "Considering the cellularity of the bone marrow, the biopsy appears to exhibit:" "Normal cellularity with balanced hematopoietic elements" "Increased cellularity with numerous erythroid precursors" "Increased cellularity with granulocytic hyperplasia" "A decrease in overall cellularity with adipose replacement" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1421.jpg" -"1422" "What is the pattern of staining observed in the myocytes?" "Perinuclear staining" "Membranous staining" "Diffuse cytoplasmic staining" "Nuclear staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1422.jpg" -"1423" "What do the morphological features of the cells indicate about the type of muscle tissue represented in this image?" "Cardiac muscle due to the presence of cross-striations" "Skeletal muscle due to multiple nuclei" "Non-muscle tissue due to the absence of elongated cells" "Smooth muscle due to the lack of striations" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1423.jpg" -"1424" "What is the predominant chromatin pattern observed in the nuclei of the cells within this histological image?" "Cartwheel" "Vesicular" "Salt-and-pepper" "Smudged" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1424.jpg" -"1425" "The tissue architecture in the image is most indicative of:" "Dense cellular infiltrate" "Glandular hyperplasia" "Mature adipose tissue" "Normal organized epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1425.jpg" -"1426" "What is the morphology of the nuclei in the predominantly stained cells observed in the given tissue section?" "Hyperchromatic and irregular" "Multi-lobulated" "Elongated and cigar-shaped" "Round with dispersed chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1426.jpg" -"1427" "Considering the overall structure and orientation of cells, what type of tissue arrangement is depicted in the image?" "Dense regular connective tissue with interlacing cells" "Dense irregular connective tissue" "Adipose tissue with large vacuoles" "Loose connective tissue with irregular fiber arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1427.jpg" -"1428" "What morphological feature is indicated by the arrows in the image?" "Karyorrhexis" "Lipid vacuoles" "Multinucleated giant cells" "Granuloma formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1428.jpg" -"1429" "What characteristic branching pattern is observed in the hyphal elements indicated by the arrows?" "Irregular branching" "Dichotomous branching" "Right angle branching" "Random branching" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1429.jpg" -"1430" "How does the background tissue staining compare to the area of acute inflammation?" "More cellular density" "More eosinophilic" "Less cellular density" "More evenly distributed" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1430.jpg" -"1431" "Based on the brown cytoplasmic staining observed in the image, which of the following immunohistochemical markers is most likely being highlighted in these cells?" "S100 protein" "Cytokeratin" "CD20" "Smooth muscle actin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1431.jpg" -"1432" "Assuming the blue nuclear counterstain in the image is hematoxylin, what characteristic of the nuclei can be discerned?" "Chromatin pattern" "Presence of nucleoli" "Hyperchromasia" "Mitotic activity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1432.jpg" -"1433" "What does the morphology of the tubular structures surrounding the glomerulus in this image suggest?" "The tubular structures appear dilated with flattened epithelium." "The tubular structures show signs of atrophy." "The tubular structures are preserved without overt signs of disruption." "The tubular structures exhibit signs of acute tubular necrosis." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1433.jpg" -"1434" "What type of cellular morphology is predominantly observed in this image?" "Squamous epithelial cells" "Spindle-shaped cells" "Fibroblasts" "Columnar epithelial cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1434.jpg" -"1435" "What morphological feature of the cells indicated by black arrows supports the identification of these cells as plasma cells?" "Multiple prominent nucleoli" "Multinucleation" "Hyperchromatic nuclei" "Eccentrically placed nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1435.jpg" -"1436" "Considering the presence of brownish pigment within the cytoplasm, which of the following best describes a potential cause for this observation?" "Presence of melanin in a melanoma" "Accumulation of lipofuscin due to aging or atrophy" "Deposition of hemosiderin as a result of hemorrhage" "Immunohistochemical staining indicating specific protein expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1436.jpg" -"1437" "Observing the middle layer of tissue, what is the predominant shape of the cell nuclei in the endometrial stroma?" "Irregular and varied" "Spindle-shaped" "Round to oval" "Long and thread-like" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1437.jpg" -"1438" "When examining the deepest visible layer in this tissue sample, the organization of cells compared to the endometrial stroma is:" "More disorganized" "Exhibits a more regular arrangement" "Similarly dense" "Consists of fewer cell types" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1438.jpg" -"1439" "What characteristic distribution of nuclei is observed in the giant cells present within the field of view?" "Nuclei lined up at the periphery of the cell" "Nuclei arranged in a single file line within the cell" "Nuclei clustered at the center of the cell" "Nuclei randomly dispersed throughout the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1439.jpg" -"1440" "Based on the cellular morphology, what type of cells are predominantly indicated by the arrow in the microscopic image?" "Mononuclear leukocytes" "Squamous epithelial cells" "Neutrophils" "Erythrocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1440.jpg" -"1441" "What histological structure can be inferred from the pattern of cells with round, clear lumens surrounding the mononuclear cells?" "Tubular structures" "Adipose tissue" "Glandular acini" "Striated muscle fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1441.jpg" -"1442" "The pink-staining extracellular matrix visible in the image is likely to be the result of which of the following staining methods?" "Periodic Acid-Schiff (PAS) staining" "Hematoxylin and Eosin (H&E) staining" "Wright's staining" "Masson's Trichrome staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1442.jpg" -"1443" "Identify the type of cells scattered within the stroma of the fibrovascular cores based on their staining characteristics." "Macrophages" "Lymphocytes" "Red blood cells" "Eosinophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1443.jpg" -"1444" "Based on the microscopic characteristics, what is the most likely staining technique used in this renal tissue sample?" "Silver staining" "Hematoxylin and Eosin (H&E)" "Periodic acid-Schiff (PAS)" "Masson's Trichrome" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1444.jpg" -"1445" "How would you characterize the extracellular matrix between the tubules in this image?" "Disorganized with multiple areas of inflammatory cells" "Dominated by large, irregularly shaped spaces suggesting edema" "Homogenous pink staining with no signs of fibrosis" "Marked by extensive fibrosis and scarring" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1445.jpg" -"1446" "Assessing the immunohistochemical staining for CD56, what can be inferred from image (b)?" "CD56 expression in all cells" "Faint immunostaining for CD56" "Absence of CD56 expression" "The presence of strong immunostaining for CD56" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1446.jpg" -"1447" "Based on the morphological characteristics observed, what type of crystalloid structures can be deduced from the tissue's appearance?" "Charcot-Leyden crystals" "Monosodium urate crystals" "Hemosiderin granules" "Calcium oxalate crystals" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1447.jpg" -"1448" "Upon examination of the stained microscopic image of the skin lesion, what is the most prominent feature of the cells in the deeper layers?" "Spindle-shaped cells with elongated nuclei and minimal cytoplasm" "Large, rounded cells with ample eosinophilic cytoplasm and prominent nuclei" "Cells with high nuclear-to-cytoplasmic ratio and irregular nuclei" "Cells with large, hyperchromatic nuclei and increased mitotic activity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1448.jpg" -"1449" "What finding in the image represents a typical 'starry sky' appearance in a tissue biopsy?" "Dark blue to purple staining of nuclei" "Scattered cells with abundant, pale cytoplasm" "Uniformly stained nuclei throughout the tissue" "Isolated, pale cytoplasmic areas within cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1449.jpg" -"1450" "Based on the basal layer morphology observed in the image, which term best describes the alteration?" "Liquefaction degeneration" "Spongiosis" "Hydropic degeneration" "Acanthosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1450.jpg" -"1451" "What is the nature of the cells found scattered in the dermis of this skin section?" "Fibroblasts" "Melanocytes" "Lymphocytes" "Neutrophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1451.jpg" -"1452" "What staining pattern is predominantly observed in the cytoplasm of the cells present in this tissue section?" "Predominantly brown staining" "Patchy blue staining" "Uniform pink staining" "Green fluorescent staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1452.jpg" -"1453" "Based on the shape of the cells in this tissue section, which type of cells are predominantly present?" "Spherical lymphocytes" "Adipocytes with large vacuoles" "Epithelial cells with a cobblestone shape" "Spindle-shaped stromal cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1453.jpg" -"1454" "What does the first arrow in the image indicate in the glomerular structure?" "Synechiae formation" "Parietal epithelial cell proliferation and extracellular matrix accumulation" "Mesangial cell proliferation" "Podocyte effacement" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1454.jpg" -"1455" "In the area indicated by the second arrow, what histopathological change is most evident?" "Tubular atrophy" "Granulomatous inflammation" "Fibrinoid necrosis" "Hyaline arteriolosclerosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1455.jpg" -"1456" "What can be inferred about the general condition of the glomerulus outside the areas indicated by the arrows?" "The glomerulus exhibits significant hyalinization" "The glomerulus shows normal cellularity with clear capillary lumina" "There is evident hypercellularity with obscured capillary lumina" "There is widespread necrosis throughout the glomerulus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1456.jpg" -"1457" "What type of cells are indicated by the presence of smaller, round nuclei with dense chromatin patterns in this tissue section?" "Neoplastic spindle cells" "Epithelial cells" "Adipocytes" "Inflammatory cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1457.jpg" -"1458" "What type of tissue architecture disruption can be inferred from the absence of distinct layers of cells within the connective tissue?" "Loss of epithelial polarity" "Preservation of normal tissue organization" "Anaplasia" "High-grade cellular atypia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1458.jpg" -"1459" "What feature of adipocytes is primarily visualized in this hematoxylin and eosin-stained tissue sample?" "Hyperchromatic, clustered nuclei" "Cytoplasm rich in mitochondria" "Multilocular lipid droplets" "Large, white, empty-looking spaces" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1459.jpg" -"1460" "In the context of the provided image, which cells are closely packed between adipocytes, distinguished by their dark-staining nuclei?" "Muscle cells" "Neutrophils" "Fibroblasts" "Hematopoietic cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1460.jpg" -"1461" "Considering the morphology depicted in this image, what type of stromal composition is identified through the eosinophilic background staining?" "Rich vascular network in loose connective tissue" "Acellular, hyalinized connective tissue" "Loose connective tissue with abundant ground substance" "Dense collageneous connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1461.jpg" -"1462" "What is the pattern of immunohistochemical staining observed in the population of cells with high antigen expression?" "Membranous staining" "Nuclear staining" "No staining" "Cytoplasmic staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1462.jpg" -"1463" "Based on the staining pattern, how does the antigen expression compare between the two populations of cells in the image?" "Both populations show equal levels of antigen expression" "The lower cells have stronger antigen expression" "The lower cells have weaker antigen expression" "The upper cells have stronger antigen expression" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1463.jpg" -"1464" "What is the most likely pathological process depicted in the image where lung tissue shows areas of disrupted architecture amid the presence of inflammatory cells?" "Healing fibrosis" "Acute bacterial pneumonia" "Pulmonary edema" "Invasive fungal infection" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1464.jpg" -"1465" "What type of epithelium is visible at the top of the image?" "Stratified squamous epithelium" "Simple columnar epithelium" "Pseudostratified ciliated columnar epithelium" "Transitional epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1465.jpg" -"1466" "What feature is indicated by the black arrow pointing to the luminal surface in the gastric tissue?" "Heavy fibrous tissue deposition" "Disrupted surface epithelial cells" "A normal layer of surface epithelial cells" "Presence of neoplastic cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1466.jpg" -"1467" "What distinctive morphology is presented by several cells in this photomicrograph?" "Multiple prominent nucleoli" "Signet ring appearance" "Multilobulated nuclei" "Spindle-shaped cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1467.jpg" -"1468" "Based on the photomicrograph, how could you best describe the nuclei of these unique cells?" "Irregular and hyperchromatic" "Small and hypochromatic" "Uniformly round and centrally located" "Large with a clear halo" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1468.jpg" -"1469" "What cellular feature is evidenced by the dense, pink structures observed in the tissue section?" "Keratin pearl formation" "Mucin deposition" "Hyalinization" "Amyloid deposits" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1469.jpg" -"1470" "Based on the image, what can be inferred about the inflammatory status of the renal tissue?" "Chronic inflammation with mononuclear cell infiltration" "No sign of inflammation" "Granulomatous inflammation" "Acute inflammation with neutrophil infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1470.jpg" -"1471" "What does the tissue architecture suggest about the tubular structures within the renal tissue?" "Normal tubular morphology and spacing" "Obstructive tubular dilation" "Tubular atrophy with widened separation" "Tubular hypertrophy with close proximity" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1471.jpg" -"1472" "Based on the distribution and intensity of the brown staining, which antigen is most likely being targeted by the immunohistochemical marker in this tissue section?" "CD45RO" "CD30" "CD3" "CD20" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1472.jpg" -"1473" "What type of cellular arrangement is predominantly observed in this micrograph?" "Palisading pattern" "Epithelioid pattern" "Storiform pattern" "Alveolar pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1473.jpg" -"1474" "Based on the microscopic features, which tissue characteristics are predominant?" "Collagenous stroma with fibroblasts" "Necrotic tissue with leukocytic infiltration" "Abundant extracellular matrix with cartilaginous tissue" "Adipose tissue with signet ring cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1474.jpg" -"1475" "Based on the histological features observed in this image, what is the most likely effect on the lumen of the arteriole?" "The lumen's size appears to be unaffected by the surrounding tissue changes" "The lumen appears partially constricted but still permits blood flow" "The lumen appears completely occluded, which would obstruct blood flow" "The lumen appears widely open, allowing for an increased blood flow" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1475.jpg" -"1476" "In the unstained cells with clear cytoplasm, what additional staining or procedure could help further identify these cells?" "Acid-fast stain" "Masson's trichrome stain" "Periodic Acid-Schiff (PAS) stain" "Hematoxylin and eosin (H&E) stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1476.jpg" -"1477" "Which cytoplasmic structure is suggested by the presence of pale perinuclear halos observed in some cells?" "Mitochondria" "Lysosomes" "Rough endoplasmic reticulum" "Golgi zone" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1477.jpg" -"1478" "What is the predominant staining pattern observed in the cells indicated by the arrows?" "Nuclear staining" "Cytoplasmic and membrane staining" "Extracellular matrix staining" "Staining absent" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1478.jpg" -"1479" "In this image at 200x magnification, what is the nature of the cytoplasm observed in the cells?" "Eosinophilic cytoplasm with dark nuclei" "Basophilic cytoplasm with pale nuclei" "Amphophilic cytoplasm with fragmented nuclei" "Eosinophilic cytoplasm with pale nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1479.jpg" -"1480" "What observation supports the possibility of a chronic inflammatory process in this tissue section?" "The presence of multinucleated giant cells" "The regularity of the tissue architecture" "The absence of cellular infiltrates" "The presence of fibrin deposits" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1480.jpg" -"1481" "Based on image B, which statement correctly describes the cell proliferation status of the tissue?" "There is a moderate level of cell proliferation with mixed Ki-67 staining." "There is a high level of cell proliferation indicated by diffuse Ki-67 staining." "The Ki-67 staining is completely absent, suggesting no cellular proliferation." "The tissue shows rare Ki-67 staining indicating a low level of cell proliferation." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1481.jpg" -"1482" "What characteristic feature of skeletal muscle fibers can be observed in this image?" "Central nuclei" "Lack of striations" "Multiple nuclei per fiber" "Peripheral nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1482.jpg" -"1483" "What does the presence of smaller, darker-stained muscle fibers in the image suggest?" "Hypertrophy" "Regeneration" "Atrophy" "Normal variation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1483.jpg" -"1484" "Considering the cellular morphology, what type of cell shape predominates in this tissue section?" "Polygonal-shaped cells" "Round-shaped cells" "Cuboidal-shaped cells" "Spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1484.jpg" -"1485" "Based on the immunohistochemical staining, which protein expression is highlighted in the tissue sample?" "Desmin" "Keratin" "CD34" "S100" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1485.jpg" -"1486" "Observing the distribution of cells within the matrix, how would you describe the cellularity?" "Moderate cellularity with variable density" "Lymphocytic infiltration" "Hypercellular areas with an increased number of cells" "Uniformly hypercellular" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1486.jpg" -"1487" "In the main image section, what does the perinuclear halo around some of the nuclei suggest?" "Cellular necrosis" "Higher degree of cell maturity" "Inflammatory cell infiltration" "Immature cell origin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1487.jpg" -"1488" "Based on the cellular arrangement observed in the image, which histological pattern is most consistent with the tissue's morphology?" "Alveolar growth" "Pseudopapillary configuration" "Trabecular organization" "Solid nesting" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1488.jpg" -"1489" "What morphological feature is indicated by the blue circles in this image of skin tissue?" "Melanocytes with prominent pigmentation" "Basaloid cells with hyperchromatic, irregular nuclei" "Skeletal muscle cells with striations" "Adipocytes with large lipid droplets" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1489.jpg" -"1490" "What is the significance of the structure indicated by the blue arrow?" "It indicates an active cell division process" "It is indicative of inert, calcified material" "It is a sign of cellular necrosis" "It represents a lipid accumulation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1490.jpg" -"1491" "What can be inferred about the red circle's contents?" "A monomorphic proliferation of basaloid cells" "Accumulation of adipose tissue" "Aggregates of calcium deposition" "A mixed cellular infiltrate indicative of inflammation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1491.jpg" -"1492" "Based on the staining patterns observed in the image, which type of cells predominantly show expression of the antigen of interest?" "Elongated cells with basally located nuclei" "Cells with large, clear central nuclei" "Cells with foamy cytoplasm" "Cells with densely stained blue nuclei and scant cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1492.jpg" -"1493" "Based on the cellular morphology observed in the image, what is the predominant type of mature cell visible within the fibrous matrix?" "Adipocytes with a large central nucleus" "Spindle-shaped cells with central oval nuclei" "Adipocytes with a small, eccentrically located nucleus" "Epithelial cells with large, round nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1493.jpg" -"1494" "What type of fibrotic structure is predominantly observed in this lung tissue image?" "Hyaline cartilage" "Elastin fibers" "Masson bodies" "Fibrin deposits" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1494.jpg" -"1495" "What cellular process is indicated by the arrow in the image?" "Megakaryocyte platelet formation" "Myeloid lineage proliferation" "Hemophagocytosis" "Erythroid precursors differentiation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1495.jpg" -"1496" "Regarding the nuclear staining intensity, what abnormal characteristic do some cells exhibit?" "Poikilochromasia with patchy staining across the tissue" "Hypochromasia with reduced nuclear staining intensity" "Hyperchromatism with increased staining intensity" "Polychromasia with multiple staining hues" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1496.jpg" -"1497" "What can be inferred about the underlying stromal tissue from the image?" "There is extensive vascular proliferation with numerous small vessels" "The extracellular matrix appears myxoid with sparse cellular components" "The stromal tissue is compact with spindle-shaped cells and densely packed extracellular matrix" "It shows loose connective tissue with abundant ground substance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1497.jpg" -"1498" "Based on the histopathological features observed in the tissue section, which layer of the epidermis shows the most prominent sign of a pathological process?" "Stratum spinosum" "Stratum granulosum" "Stratum basale" "Stratum corneum" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1498.jpg" -"1499" "Analyzing the mitotic activity in the tissue, which feature pointed by the arrow indicates active cell division?" "A mitotic figure that resembles healthy tissue cell division" "An increased number of mitotic figures" "A regular and well-organized mitotic figure" "A mitotic spindle with condensed chromosomes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1499.jpg" -"1500" "Based on the glandular architecture, which area of the body does the tissue most likely represent?" "Pancreatic tissue" "Pulmonary tissue" "Colonic mucosa" "Hepatic tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1500.jpg" -"1501" "Based on the microscopic features observed in the image, what pattern is the spindle cell neoplasm arranged in?" "Verocay body pattern" "Whorled pattern" "Fascicular pattern" "Storiform pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1501.jpg" -"1502" "What does the central region of the layered structure in the image indicate?" "Russell body accumulation" "Fibrinoid necrosis" "Granuloma with central caseous necrosis" "Keratin pearl formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1502.jpg" -"1503" "Observing the peripheral areas of the tissue, what is the possible normal tissue type or pathology indicated?" "Normal thyroid gland tissue" "Hyaline cartilage" "Dense irregular connective tissue" "Smooth muscle tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1503.jpg" -"1504" "What is the predominant staining characteristic of the large irregularly shaped structures in this microscopic image?" "Basophilic (dark blue)" "Acidophilic (bright red)" "Hematoxylin (reddish/brown)" "Eosinophilic (pinkish)" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1504.jpg" -"1505" "Based on staining characteristics, what can be inferred about the cytoplasm of these cells?" "Presence of keratin" "Presence of collagen fibers" "Presence of glycogen deposits" "Presence of smooth muscle actin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1505.jpg" -"1506" "What does the blue counterstain in the image predominantly highlight?" "Collagen fibers" "Extracellular matrix" "Nuclei of the cells" "Red blood cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1506.jpg" -"1507" "Analyzing the image, what is the morphology of the cells surrounding the round to oval spaces?" "Spindle-shaped with elongated nuclei" "Irregular with hyperchromatic nuclei" "Cuboidal to columnar with uniform nuclei" "Polyhedral with abundant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1507.jpg" -"1508" "Considering the presence of glandular structures with a central lumen lined by columnar epithelial cells, what is the most likely anatomical origin of this tissue section?" "Glandular tissue from the pancreas" "Glandular tissue from the stomach" "Glandular tissue from the duodenum" "Glandular tissue from the thyroid" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1508.jpg" -"1509" "What cellular characteristic among the infiltrating round cells suggests the presence of immature granulocytic precursors in the stroma?" "Indistinct nuclear shape and dense chromatin pattern" "Cytoplasm rich in eosinophilic granules" "Large, distinct nucleoli within the nuclei" "Nuclei with regular, round shapes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1509.jpg" -"1510" "Which of the following best describes the elongated structures observed in the cytological smear image?" "Microfilariae parasites" "Collagen fibers" "Striated muscle fibers" "Erythrocytes with central pallor" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1510.jpg" -"1511" "What is the significance of not observing testicular tissue elements such as spermatogenic cells or Sertoli cells in this cytological smear?" "It points to a non-testicular source of the cytological sample" "It suggests that the sample may have been improperly collected" "It indicates a potential pathology within the testis" "It confirms the presence of microfilariae parasites" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1511.jpg" -"1512" "Based on the characteristics of the capillary loops in the histological section, which of the following best describes the observed changes?" "Normal cellularity of capillary walls" "Thinned capillary walls" "Aneurysmal dilation of capillary loops" "Endocapillary hyperplasia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1512.jpg" -"1513" "In evaluating the architecture of the glomeruli, how does increased cellularity affect the structure as seen in this histological image?" "It causes global sclerosis of the glomerulus" "It leads to thickening and narrowing of the capillary lumens" "It leads to the formation of synechiae" "It results in a lobulated appearance of the glomeruli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1513.jpg" -"1514" "What does the eosinophilic cytoplasm visible in the cells suggest?" "Cytoplasmic filaments" "High RNA content" "Glycogen accumulation" "High lipid content" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1514.jpg" -"1515" "Based on the overall cellular and tissue architecture observed, which of the following descriptions is most consistent with the image?" "Fibrous connective tissue with abundant extracellular matrix" "Uniform glandular structures with columnar cells" "Neoplastic tissue with a relatively uniform cell population" "Striated muscle tissue with cross-striations and intercalated discs" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1515.jpg" -"1516" "What feature is indicated by the arrows in the image that suggests a particular type of cell morphology?" "Multinucleated giant cells" "Lymphocytes" "Squamous epithelial cells" "Signet ring cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1516.jpg" -"1517" "Based on the morphological features, which of the following characteristics is visible in the nuclei of specific cells pointed out in the image?" "Macronucleoli" "Marginated chromatin" "Hyperchromasia" "Anisonucleosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1517.jpg" -"1518" "What type of extracellular matrix component can be inferred from the pink-stained areas within the image?" "Elastic fibers" "Collagen fibers" "Basement membrane" "Reticular fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1518.jpg" -"1519" "What does the general appearance of the tissue in the image indicate about the presence of inflammatory response?" "Presence of granulomatous inflammation" "Presence of neutrophilic infiltration" "Lack of significant lymphocytic infiltration" "Signs of chronic inflammation with extensive fibrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1519.jpg" -"1520" "Based on the cytoplasmic staining pattern observed, which of the following antigens is most likely being targeted by the immunohistochemical stain?" "Hemoglobin" "Melanin" "Keratin" "Glycogen" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1520.jpg" -"1521" "Based on the cellular morphology, what type of cells are predominantly seen in this tissue section?" "Neutrophils" "Epithelial cells" "Fibroblasts" "Adipocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1521.jpg" -"1522" "What does the pink staining in the extracellular matrix signify?" "Collagen fibers" "Cytoplasm and extracellular matrix components" "Basic cellular components" "Acidic cellular components" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1522.jpg" -"1523" "Which of the following best describes the pattern of the connective tissue in the context of this skeletal muscle section?" "Large, amorphous areas lacking any distinct fibers or cells" "Thick, collagenous fibers running parallel with the muscle fibers" "Dense irregular connective tissue with abundant fibroblasts" "Thin pink strands interspersed with the adipose and muscle tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1523.jpg" -"1524" "What is the predominant cellular morphology evident in the glands of this tissue section?" "Cystic cells with clear cytoplasm and regular nuclei" "Uniform cells with small, round nuclei and ample cytoplasm" "Atypical cells with high nuclear-to-cytoplasmic ratios" "Cells with small, hyperchromatic nuclei and abundant stroma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1524.jpg" -"1525" "The presence of what type of cells, signifying an active vasculitic process, can be hypothesized from this image?" "Lymphocytes with scant cytoplasm and dense chromatin" "Macrophages with large nuclei and foamy cytoplasm" "Eosinophils with dark, round nuclei and abundant cytoplasm" "Neutrophils with pyknotic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1525.jpg" -"1526" "What morphological feature is predominantly seen in the nuclei of the cells in this image?" "Multilobated nuclei" "Smudged nuclei" "Hypersegmented nuclei" "Eccentrically located rounded nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1526.jpg" -"1527" "What is the cytoplasmic appearance of the cells in this image?" "Moderate in amount with light blue color" "Abundant with foamy appearance" "Vacuolated with multiple clear spaces" "Deeply basophilic with scant amount" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1527.jpg" -"1528" "What is the dominant cell type observed in this tissue section?" "Multinucleated giant cells" "Columnar epithelial cells" "Round cells with ample cytoplasm" "Spindle-shaped cells with elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1528.jpg" -"1529" "Based on the tissue architecture and cell morphology, which characteristic is not apparent in this microscopic view?" "Hypercellularity" "Significant inflammatory infiltrate" "Necrosis" "Well-organized tissue arrangement" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1529.jpg" -"1530" "Analyzing the tissue matrix and cell distribution, which is the most likely microscopic pathological state indicated by the presence of cells closely packed together in the image?" "Lymphoid aggregate formation" "Adipose tissue degeneration" "Muscle tissue hypertrophy" "Dysplastic epithelial changes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1530.jpg" -"1531" "Based on this image, which type of cell is characterized by a large cytoplasmic area and an eccentrically placed nucleus?" "Adipocytes" "Myeloblasts" "Megakaryocytes" "Erythroblasts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1531.jpg" -"1532" "What is the predominant background matrix seen in the histological image?" "Myxoid stroma" "Adipose tissue" "Hyaline cartilage" "Dense fibrous connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1532.jpg" -"1533" "How would you describe the nuclear features of the cells in the inset image?" "Variably sized and vesicular" "Large with smudged chromatin" "Small and hyperchromatic" "Uniform and hypo-chromatic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1533.jpg" -"1534" "The nuclear-to-cytoplasmic ratios in the cells are:" "Consistently low" "Uniform across all cells" "High with minimal cytoplasm" "High with moderate cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1534.jpg" -"1535" "Which structure is lined by a single layer of epithelial cells and appears lighter pink in the image?" "Bowman's capsule" "Interstitial spaces" "Glomerular tufts" "Tubules" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1535.jpg" -"1536" "Based on the image provided, how would you describe the appearance of the glomeruli?" "They contain excessive extracellular matrix deposition" "They display normal cellularity with densely packed cells" "They appear atrophic with decreased cellularity" "They show evidence of significant hypercellularity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1536.jpg" -"1537" "Based on the AQP4 immunohistochemical staining pattern observed in panel A, what is the most likely characteristic of the astrocytic end-feet?" "Well-defined, consistently shaped structures across the tissue" "Homogeneous and intense staining throughout the end-feet" "Absence of any brown staining indicative of AQP4" "Irregular brown deposits corresponding with the locations of astrocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1537.jpg" -"1538" "Comparing the staining patterns in panels A and B, what is a distinguishing feature of the astrocytic processes in panel A that contrasts with the cells observed in panel B?" "The astrocytic processes have more uniform shapes compared to the cells in panel B" "The astrocytic processes show a stronger and more diffuse staining pattern than the cells in panel B" "The astrocytic processes exhibit a higher density of staining relative to the spaces between them compared to panel B" "The astrocytic processes appear faint and lack a well-defined structure compared to the cells in panel B" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1538.jpg" -"1539" "What feature of cells on the right side of the image is indicative of rhabdomyosarcoma?" "Large, round nuclei within a clear extracellular matrix" "Spindle-shaped cells with densely eosinophilic cytoplasm arranged in fascicles" "Abundant cytoplasm with small, indistinct nuclei" "Cells with a high nucleus-to-cytoplasm ratio" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1539.jpg" -"1540" "Based on the staining characteristics in the image, which of the following best describes the bone marrow content?" "Hypercellular with dense blue-staining cells" "Acellular with no visible cells" "Hypocellular with sparse blue-staining cells" "Consisting mainly of elongated cells with few blue-staining cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1540.jpg" -"1541" "Based on the cellular morphology, which feature is indicative of malignancy in this image?" "Presence of stripped nuclei" "Single prominent nucleoli within nuclei" "Uniform nuclear size" "Monotonous cell population" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1541.jpg" -"1542" "What cellular morphology is evident in the tissue sample when focusing on the nuclei?" "Round and densely stained nuclei" "Elongated, spindle-shaped and darkly stained nuclei" "Pleomorphic nuclei with irregular contours" "Hyperlobulated nuclei with prominent nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1542.jpg" -"1543" "Considering the staining properties, what is the central core of eosinophilic material most likely composed of?" "Collagen fibers" "Hyaline cartilage" "Smooth muscle tissue" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1543.jpg" -"1544" "Which type of epithelium is represented on the left side of the image?" "Stratified squamous epithelium" "Transitional epithelium" "Simple columnar epithelium" "Pseudostratified columnar epithelium" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1544.jpg" -"1545" "In the context of this tissue section, what does the eosinophilic (pink-stained) material below and to the right indicate?" "Skeletal muscle tissue" "Mature lamellar bone tissue" "Dense connective tissue" "Adipose tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1545.jpg" -"1546" "Which statement best describes the status of the glomerular basement membrane in this image?" "The glomerular basement membrane shows significant duplication." "The glomerular basement membrane appears to be normal without thickening." "The glomerular basement membrane is distinctly thickened." "There is appreciable disruption in the continuity of the glomerular basement membrane." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1546.jpg" -"1547" "Assessing the interstitial tissue in this section, what is the level of interstitial infiltration observable?" "There is a severe mononuclear cell infiltration throughout the interstitial tissue." "The interstitial tissue is replaced extensively by mononuclear cell infiltration." "There is no mononuclear cell infiltration visible in the interstitial tissue." "A mild mononuclear cell infiltration is present scattered within the interstitial tissue." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1547.jpg" -"1548" "Based on the morphology visible in this image, which cell population suggests the presence of neoplastic cells?" "Cells with a uniform blue staining throughout" "Cells with a green fluorescent staining pattern" "The majority of cells that do not exhibit brown staining" "The larger, elongated cells with distinct boundary" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1548.jpg" -"1549" "What can be inferred about the structural features of the tissue matrix in this image?" "The matrix reveals distinct layers of cellular organization" "The matrix appears relatively homogeneous without distinct structural features" "The matrix has well-defined, tubular structures" "The matrix displays a mesh-like fibrous pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1549.jpg" -"1550" "What feature is indicated by the clear cytoplasmic vacuole observed within many of the cells at the center of the tissue section?" "Lipid accumulation" "Glycogen deposition" "Intracytoplasmic mucin" "Keratin pearl formation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1550.jpg" -"1551" "The nuclei of the cells in this image have which of the following characteristics?" "Large, irregularly shaped, angular nuclei with uneven chromatin distribution." "Small, round, and uniform nuclei with evenly distributed chromatin." "Bisected nuclei with pronounced nucleoli seen in most cells." "Elongated, spindle-shaped nuclei with thickened nuclear membranes." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1551.jpg" -"1552" "Based on the image, what can be inferred about the cytoplasmic characteristics of these cells?" "The cytoplasm is abundant with a basophilic staining pattern." "The cytoplasm appears modestly eosinophilic and indicative of an astrocytic lineage." "Cytoplasmic features suggest a lymphocytic origin with dense chromatin." "Cells have a scanty, clear cytoplasm with peripheral margination." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1552.jpg" -"1553" "Based on the staining pattern observed, which of the following markers is likely highlighted by the red stain?" "Endothelial cell antigen like CD31" "Connective tissue marker like vimentin" "Epithelial cell marker like cytokeratin" "Proliferation marker like Ki-67" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1553.jpg" -"1554" "What is the most likely composition of the pink-staining extracellular background material in the image?" "Collagen fibers" "Elastic fibers" "Reticular fibers" "Mucopolysaccharides" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1554.jpg" -"1555" "What pattern of cell arrangement is prominently observed in the microscopic image?" "Storiform" "Rosette" "Papillary" "Alveolar" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1555.jpg" -"1556" "Based on the cellular morphology, what types of cell shapes are most prevalent in the tissue sample?" "Squamous and transitional" "Round and spheroid" "Epithelioid and spindle-shaped" "Cuboidal and columnar" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1556.jpg" -"1557" "Which characteristic of the cells' nuclei can be observed in this microscopic image?" "Hyperchromatic" "Hypochromatic" "Multinucleated" "Vesicular with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1557.jpg" -"1558" "How would you describe the staining pattern of the selected atypical cells?" "Clear cells with no staining" "A pink cytoplasmic staining with no specific pattern" "A uniform blue staining throughout the cell" "A brown cytoplasmic staining indicative of specific marker expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1558.jpg" -"1559" "What is the most likely type of tissue represented in this microscopic image?" "Stratified squamous epithelium" "Smooth muscle tissue" "Cardiac muscle tissue" "Neural tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1559.jpg" -"1560" "Based on the cellular morphology, what aspect of the nuclei is most apparent in the smooth muscle cells of this tissue section?" "Signet-ring appearance" "Multilobed structure" "Uniformity in size and shape" "Presence of prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1560.jpg" -"1561" "Considering the organization of the smooth muscle cells in this image, how would you best describe their arrangement?" "Forming glandular structures" "Arranged in a palisading pattern" "Disorganized with haphazard orientation" "Organized in uniform, parallel bundles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1561.jpg" -"1562" "How would one describe the cellular characteristics seen at the structures identified by '2'?" "Irregularly shaped cells forming a dense matrix" "Large polygonal cells with prominent nucleoli" "Homogeneous cells with minimal cytoplasmic staining" "Spindle-shaped cells with a syncytial arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1562.jpg" -"1563" "Assessing the intensity and distribution of staining, what can be inferred about the expression of the protein encoded by the ERCC1 gene?" "Uniform intensity in all cells indicating consistent low-level expression" "Lowest intensity in all cells with no expression of ERCC1" "Variable intensity with predominant low expression and few exceptions" "Highest intensity in a significant proportion of cells suggesting high expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1563.jpg" -"1564" "The presence of which of the following features in the image would be consistent with the morphology of benign breast tissue undergoing secretory changes?" "Sparse, disconnected glandular spaces" "Sheets of undifferentiated, hyperchromatic cells" "Irregular glandular spaces with surrounding spindle-shaped stromal cells" "Dense, homogeneous stromal tissue without glandular spaces" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1564.jpg" -"1565" "Based on the immunohistochemical staining pattern observed in panel (a), which cellular structure appears to be predominantly highlighted?" "Mitochondria" "Endoplasmic reticulum" "Cell membrane" "Nucleus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1565.jpg" -"1566" "In panel (b), the brown staining indicative of the presence of Factor VIII is primarily associated with which of the following features?" "Basement membrane" "Extracellular matrix" "Cellular structures" "Cytoplasmic inclusions" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1566.jpg" -"1567" "Based on the image, what do the irregularly shaped structures lined by flattened cells likely represent?" "Artifactual tissue separation" "Normal physiological tissue compartments" "Ductal structures in a glandular tissue" "Vascular channels within tumorous stroma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1567.jpg" -"1568" "What best describes the staining pattern observed in the cytoplasm of the cells in this tissue section?" "Granular with varying intensities of staining" "Uniform intense staining throughout the cytoplasm" "Homogeneous with no distinct granularity" "Patchy with areas of unstained cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1568.jpg" -"1569" "Considering the organization of cells, how would you describe the arrangement of the epithelial cells in this tissue sample?" "Multilayered and pseudostratified" "Disorganized and randomly distributed" "Aligned in an orderly, columnar fashion" "Single-layered and uniform" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1569.jpg" -"1570" "What is the predominant staining pattern observed in the cells?" "Predominantly nuclear staining" "Predominantly cytoplasmic staining" "No significant staining observed" "Cytoplasmic and nuclear co-staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1570.jpg" -"1571" "What characteristic feature distinguishes the smaller cells with dark, compact nuclei?" "The paler cytoplasm" "The larger cell size" "The appearance of mature lymphocytes" "The presence of nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1571.jpg" -"1572" "Based on the immunohistochemical staining pattern observed in the image, which marker might these cells be positive for?" "CD20" "Estrogen Receptor (ER)" "HER2/neu" "CD45" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1572.jpg" -"1573" "What staining pattern is predominantly observed in the cells of this tissue section?" "No staining" "Cytoplasmic staining" "Membranous staining" "Nuclear staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1573.jpg" -"1574" "Based on the arrangement and morphological features, how would you characterize the origin of the tissue in the image?" "Muscle tissue origin" "Neural tissue origin" "Connective tissue origin" "Epithelial tissue origin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1574.jpg" -"1575" "Based on the specific staining pattern observed in the microscopic image, what is the likely identity of the positively stained components?" "Caldesmon protein" "Lipids" "Cytoplasmic enzymes" "Nucleic acids" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1575.jpg" -"1576" "Considering the overall tissue architecture in the microscopic image, what can be inferred about the organization and health of the tissue sample?" "The tissue shows features of inflammation" "The tissue is disorganized and possibly neoplastic" "The tissue is healthy and well-organized" "The tissue exhibits normal regenerative changes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1576.jpg" -"1577" "What is the predominant shape of the cells located at the periphery of the granuloma?" "Cuboidal" "Spherical" "Spindle-shaped" "Squamous" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1577.jpg" -"1578" "How does the density of the cells in the central region containing the eggs compare to the cell density at the edges of the granuloma?" "The density is greater in the central region containing the eggs." "The density is the same in both regions." "The density is less in the central region containing the eggs." "The central region contains no cells, only eggs." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1578.jpg" -"1579" "What is the orientation of the nuclei within the columnar epithelial cells observed in the intestinal villi?" "Concentrated in the center of the epithelial cells, with a circular arrangement" "Uniformly aligned at the apical surface of the epithelial cells" "Randomly oriented at varying levels within the epithelial cells" "Basally located and closely packed, presenting a regular pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1579.jpg" -"1580" "In the connective tissue core of the villi (lamina propria), what is the appearance of the nuclei?" "The nuclei are elongated and spaced out evenly" "Nuclei are irregularly shaped and diffusely scattered" "Nuclei possess a hyperchromatic appearance and form palisading patterns" "The nuclei are large, round and densely clustered" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1580.jpg" -"1581" "Based on the histological features observed, how would you characterize the staining pattern in this image?" "Nuclei stained darkly and cytoplasm stained in varying shades of lighter color" "Cytoplasm with dark granular inclusions and clear unstained nuclei" "Eosinophilic cytoplasm and hypochromatic nuclei" "Uniformly basophilic staining throughout the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1581.jpg" -"1582" "In the given histological image, what feature is indicated by the presence of large arrows?" "Areas of ischemic tissue damage" "Accumulation of extracellular matrix components" "Evidence of high mitotic activity with visible mitotic figures" "Presence of inflammatory cell infiltrates" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1582.jpg" -"1583" "What is the predominant cell type visible in the image based on the cytoplasmic characteristics after being stained with hematoxylin and eosin?" "Lymphocytes with a high nucleus-to-cytoplasm ratio" "Smooth muscle cells with elongated eosinophilic cytoplasm" "Epithelial cells with abundant basophilic cytoplasm" "Adipocytes with prominent vacuoles and scant eosinophilic cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1583.jpg" -"1584" "In Panel B, where is the black arrow indicating the presence of hyperplasia?" "In the renal tubular epithelium" "In the uroepithelium" "Within the glomerular capillary tuft" "In the renal corpuscle" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1584.jpg" -"1585" "Considering Panel D, what pathological feature does the black arrow most likely indicate?" "A segment of normal uroepithelium with regular cell turnover" "Areas of fibrosis with increased interstitial collagen deposition" "Disruption of the uroepithelial barrier caused by inflammatory infiltrate" "Clusters of neoplastic cells forming a tumor mass" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1585.jpg" -"1586" "Analyzing the cytoplasmic characteristics in the image, what can be observed about the ratio of nuclear to cytoplasmic material?" "The cytoplasm to nuclear ratio is about the same, suggesting normal cellular morphology" "The cytoplasm is abundant and well-defined, making nuclei less prominent" "The cytoplasm is scant, which makes the nuclei appear prominent" "The cytoplasm is scant, which makes the nuclei appear inconspicuous" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1586.jpg" -"1587" "Identify the feature indicative of cells undergoing cell division in the image." "Cells with a single, condensed nucleus" "Abundant cytoplasm with multiple nuclei" "Darker structures contrasting against the lighter cytoplasmic background" "Uniformly stained nuclei with no visible structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1587.jpg" -"1588" "Considering the pattern of immunohistochemical staining observed in this image, which cellular component most consistently shows strong staining?" "Extracellular matrix" "Nuclear region of select cells" "Cell membrane of all cells" "Cytoplasm of all cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1588.jpg" -"1589" "What is a possible histopathological feature that suggests an ongoing inflammatory response in the tissue seen in the image?" "Uniform size and shape of cells" "Clear spacing around cells indicative of edema" "Hyperkeratosis of the uppermost layer" "Presence of multinucleated giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1589.jpg" -"1590" "Which cellular morphology predominantly characterizes the tissue observed in the microscopic image?" "Cuboidal cells with central, rounded nuclei" "Columnar cells with basal nuclei" "Spindle-shaped cells with elongated, wavy nuclei" "Squamous cells with flat, atypical nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1590.jpg" -"1591" "In the presented slide of testicular tissue, what staining characteristic indicates the occurrence of apoptosis within the seminiferous tubules?" "Darker stained nuclei" "Dark brown nuclear staining" "Lighter stained interstitial cells" "Pale blue cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1591.jpg" -"1592" "What cellular feature is indicated by the strong brown staining observed at the periphery of certain cells in this image?" "Cell-cell adhesion molecules" "Cytoplasmic granules" "Peripheral membrane proteins" "Cell nucleus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1592.jpg" -"1593" "What is the spatial distribution pattern of positively stained cells in this tissue section?" "Isolated and randomly interspersed throughout the tissue" "Uniformly distributed throughout the tissue" "Predominantly localized at the tissue periphery" "Clustered in specific regions within the tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1593.jpg" -"1594" "Based on the histopathological features observed, which feature does not support the finding of apoptotic keratinocytes?" "Cells that are markedly larger than the surrounding keratinocytes" "Condensed, darkly-stained nuclei" "Large, clear cytoplasmic vacuoles" "Eosinophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1594.jpg" -"1595" "Which cellular morphology is evident in the cells observed in the image?" "Polyhedral with centrally located nuclei" "Spindle-shaped with elongated nuclei" "Cuboidal with uniform nuclei" "Round to oval with abundant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1595.jpg" -"1596" "Based on the intensity and distribution of the brown staining seen in the microscopic image, which antigen is most likely being targeted by the immunohistochemical stain?" "CD3" "CD4" "CD20" "CD8" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1596.jpg" -"1597" "What is the most likely staining method used in this microscopic image?" "Hematoxylin and Eosin (H&E) stain" "Periodic Acid-Schiff (PAS) stain" "Acid-fast stain" "Oil Red O stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1597.jpg" -"1598" "Based on the morphology observed, what type of structures predominate in this image?" "Pseudohyphae without true septations" "Bacterial chains" "Isolated yeast cells" "Hyphae with true septations" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1598.jpg" -"1599" "What is the context where these fungal structures are likely to be found, based on the background material observed in the image?" "Cerebrospinal fluid" "Sputum specimen" "Ascitic fluid" "Skin scraping" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1599.jpg" -"1600" "Based on the microscopic characteristics seen in the image, what is the prominent pathological feature observed in some hepatocyte nuclei?" "Macronucleoli" "Binucleation" "Nuclear vacuolation" "Karyorrhexis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1600.jpg" -"1601" "In the section of colonic mucosa provided, what cellular characteristic is identified at the site marked with an asterisk (*)?" "Clear cytoplasmic vacuoles" "Presence of mitotic figures" "Increased nuclear-cytoplasmic ratio" "Hyperchromatic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1601.jpg" -"1602" "Based on the image, which aspect best describes the nuclei of the cells observed?" "Variable in size with hyperchromatic appearance" "Regularly arranged with clear nucleoli" "Small with inconspicuous nucleoli" "Uniform in size with fine chromatin distribution" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1602.jpg" -"1603" "Which statement best reflects the overall arrangement of the cells in the image?" "There is a single layer of cells with columnar morphology" "Cells are well-differentiated with a regular pattern" "Cells exist in a palisading arrangement" "Cells are clustered with a lack of organizational structure" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1603.jpg" -"1604" "What is the arrangement pattern of the spindle-shaped cells in the microscopic image?" "Storiform pattern" "Fascicular pattern" "Palisading pattern" "Haphazard arrangement" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1604.jpg" -"1605" "Upon observation of the epithelial cells in the image, what morphological feature is indicated by the presence of yellow arrows?" "Apoptosis with apoptotic bodies" "Cytoplasmic vacuolation" "Single prominent nucleolus within the nucleus" "Multinucleation with multiple nuclei within a single cell cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1605.jpg" -"1606" "What cellular inclusion is signified by the black arrow in the microscopic image?" "Lipofuscin pigment" "Glycogen deposits" "Intranuclear inclusion" "Hemosiderin granules" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1606.jpg" -"1607" "Based on the image, which cell layer is consistent with having the highest nucleus-to-cytoplasm ratio?" "The superficial flat cell layer" "The denser connective tissue deeper in the lamina propria" "The loose connective tissue of the lamina propria" "The layer below the superficial flat cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1607.jpg" -"1608" "What characteristic is not observed in the epithelial tissue layer in this image?" "A single layer of columnar epithelium" "Basal cells at the base of the epithelium" "Superficial cells lacking nuclei" "Elongated structures known as rete ridges" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1608.jpg" -"1609" "In the immunohistochemically stained tissue section, which subcellular component primarily exhibits the brown staining?" "Cell membrane" "Mitochondria" "Cytoplasm" "Nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1609.jpg" -"1610" "In the regions marked with asterisks, which cell type is predominantly observed?" "Osteoblasts" "Fibroblasts" "Adipocytes" "Chondrocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1610.jpg" -"1611" "In the areas labeled 'BG', what is the microscopic characteristic of the matrix?" "Dense and homogeneous matrix" "Large adipose tissue compartments" "Presence of abundant collagen fibers" "Loose and heterogeneous matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1611.jpg" -"1612" "What feature is most consistently observed in the nuclei of these cells?" "Mono-nucleation with small, inconspicuous nucleoli" "Multi-nucleation with small and uniformly stained nuclei" "Prominent nucleoli within large and irregularly shaped nuclei" "Equally sized and regularly shaped nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1612.jpg" -"1613" "What is the predominant staining pattern of the epithelial cells observed in the image?" "Homogeneously dark staining throughout the cells" "Uniformly densely stained cytoplasm with dark nuclei" "Lightly stained cytoplasm with darkly stained nuclei" "Strong cytoplasmic immunostaining with light nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1613.jpg" -"1614" "How would you describe the uniformity of cell size and shape within this tissue sample?" "The cells are uniform in size and shape" "The cells vary in both size and shape" "The cells are uniform in size but vary in shape" "The cells vary widely in size but are uniform in shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1614.jpg" -"1615" "Considering the presence of immunoexpression, how would you categorize the level of cytoplasmic staining intensity in the cells?" "Uniform and strong cytoplasmic staining across all cells" "Weak and sparse cytoplasmic staining" "No cytoplasmic staining" "Moderate to strong cytoplasmic staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1615.jpg" -"1616" "Regarding cell morphology, which statement accurately describes the cells observed in the tissue?" "The cells appear to be predominantly large with abundant eosinophilic cytoplasm" "There is a wide variation in cell size, with giant cells dominating the field" "The cytoplasm of the cells is abundant and stains intensely with hemosiderin" "The cells are medium-sized with a high nuclear-to-cytoplasmic ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1616.jpg" -"1617" "Which of the following best describes the topmost layer of the epidermis in the image?" "Anucleate corneocytes" "Retention of nuclei within keratinocytes" "Granular cell layer hypertrophy" "Melanocyte proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1617.jpg" -"1618" "What is the condition of the tubular structures indicated by the blue arrows?" "Hypertrophy of the lining epithelial layer" "Thinning of the lining epithelial layer" "Hyperplasia of the lining epithelial layer" "Normal thickness of the lining epithelial layer" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1618.jpg" -"1619" "In terms of cellular morphology, how would you characterize the nuclei within the interstitial tissue?" "Hyperchromatic and pleomorphic" "Hyperchromatic and monomorphic" "Hypochromatic and pleomorphic" "Oligochromatic and pleomorphic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1619.jpg" -"1620" "What can be inferred about the cellularity within the seminiferous tubules as compared to their usual architecture?" "Marked hypercellularity" "Normal cellularity" "Loss of cellularity" "Markedly variable cellularity" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1620.jpg" -"1621" "Considering the cell morphology and the matrix, which description best fits the tissue characteristic?" "Loose connective tissue with abundant extracellular matrix" "Muscle tissue with cross-striations" "Adipose tissue with large, vacuolated cells" "Fibrillary matrix with embedded glial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1621.jpg" -"1622" "Based on the image, how would you describe the erythroid maturation?" "Presence of all erythroid maturation stages from proerythroblasts to orthochromatic erythroblasts" "Erythroid maturation characterized by lacking distinct maturing stages" "Even distribution of erythroid precursors suggestive of healthy erythropoiesis" "Overrepresentation of basophilic erythroblasts indicating accelerated erythroid maturation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1622.jpg" -"1623" "Based on the contents of the cystic cavity, which of the following is most likely to fill the cavity?" "Fluid or air" "Dense cellular debris" "Mucin" "Keratinous material" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1623.jpg" -"1624" "Within the context of this image, what histopathological characteristic is often seen in conditions that lead to damage or destruction of the basal layer of skin?" "Disorganized arrangement of vascular structures" "Excessive eosinophilic staining in the superficial layers" "Hyperplastic growth of spindle-shaped cells" "High degree of pigmentation resembling melanin deposition" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1624.jpg" -"1625" "What additional structure can be observed in the dermal layer, and how does its presence influence the diagnosis?" "A sweat gland, suggesting a glandular pathology" "A hair follicle, contributing to a diagnosis of an inflammatory process" "A sebaceous gland, indicative of a sebaceous lesion" "A blood vessel, not contributing to a specific diagnosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1625.jpg" -"1626" "Based on the cellular morphology observed, what pattern of staining is suggested by the appearance of the cells in the tissue?" "Staining highlighting intracellular protein distribution" "Extracellular matrix staining" "Nuclear staining with peripheral accentuation" "Uniform cytoplasmic staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1626.jpg" -"1627" "Considering the staining pattern and cellular morphology, which protein is likely targeted by the chromogen used in this histological section?" "Desmin" "Cytokeratin" "Vimentin" "Calponin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1627.jpg" -"1628" "Considering the cell morphology and staining, what feature does the cytoplasm of the cells prominently display?" "Basophilic cytoplasm due to RNA content" "Eosinophilic cytoplasm indicating high protein concentration" "Clear cytoplasm as observed in lipid-laden macrophages" "Granular cytoplasm typical of granulocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1628.jpg" -"1629" "What does the background material of the image suggest about hematopoiesis in this tissue sample?" "Lack of heterogeneous appearance suggesting suppressed hematopoiesis" "Fibrotic changes typical of myelofibrosis" "Hypercellular marrow indicative of active hematopoiesis" "Fatty infiltration consistent with marrow hypoplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1629.jpg" -"1630" "Based on the histological features visible in this image, which of the following best describes the observed tissue's status?" "Severe glandular hyperplasia with significant atypia" "Normal proliferation consistent with the secretory phase" "Moderate to marked glandular and stromal proliferation" "Highly atrophic with scarcity of glandular structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1630.jpg" -"1631" "The eosinophilic content in section 'C' is indicative of what process or material, commonly seen in the pathological state hinted by this image?" "Fibrin exudate" "Keratin debris" "Mucoid accumulation" "Collagen deposition" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1631.jpg" -"1632" "Based on the nuclear characteristics of the epithelial cells, what feature is evident?" "Anisonucleosis" "Multinucleation" "Pseudostratification" "Nuclear hyperchromasia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1632.jpg" -"1633" "What feature is observed in the nuclei of the epithelial cells lining the gland-like structures in the image?" "Round nuclei with prominent nucleoli" "Uniform nuclear spacing without overlap" "Monotonous and small nuclei" "Hyperchromatic and elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1633.jpg" -"1634" "Based on the presence of complex branching and budding of glands in the image, what is the most likely characterization of this tissue?" "Non-invasive growth pattern" "Low-grade dysplasia" "High mitotic activity indicative of invasive growth" "Simple tubular architecture" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1634.jpg" -"1635" "How does the stroma surrounding the gland-like structures in the image appear?" "Loose and myxoid" "Regular, with dense collagen bands" "Desmoplastic with sparse inflammatory infiltrate" "Vascular with numerous blood vessels" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1635.jpg" -"1636" "What is the predominant cellular morphology observed in these cells?" "Spindle-shaped cells with elongated nuclei" "Cuboidal cells with clear cytoplasm" "Large, polygonal cells with abundant eosinophilic granular cytoplasm" "Small, round cells with high nuclear-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1636.jpg" -"1637" "What does the appearance of the nuclei suggest about the cells?" "The nuclei display anisonucleosis and pleomorphism" "The nuclei are uniform in size with dense chromatin, suggestive of benign cells" "The nuclei are not visible, which is typical in necrotic tissue" "The nuclei are small and hyperchromatic, indicating a high mitotic rate" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1637.jpg" -"1638" "Based on the cellular characteristics, what type of pathology is most likely represented in this microscopic image?" "Myogenic differentiation as seen in rhabdomyosarcoma" "Dysplastic squamous cells typical of papilloma" "Inflammatory infiltration of leukocytes" "Oncocytic changes associated with certain tumors" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1638.jpg" -"1639" "Which type of staining is evident in the hepatocytes of this hepatic tissue section?" "Masson's trichrome staining" "PAS (Periodic acid–Schiff) staining" "Hematoxylin and eosin (H&E) staining" "Perls' Prussian blue staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1639.jpg" -"1640" "Upon inspection of the hepatocytes and macrophages within this tissue section, what pathology could be suggested by the morphological findings?" "Wilson's disease" "Alcoholic liver disease" "Viral hepatitis infection" "Hemochromatosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1640.jpg" -"1641" "What type of giant cells are present in the tissue section?" "Reed-Sternberg cells" "Touton-type giant cells" "Langhans-type giant cells" "Foreign body giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1641.jpg" -"1642" "Based on the image, what cellular morphology predominantly indicates an immune response?" "Granulomatous infiltrate" "Neutrophilic infiltration" "Necrotizing inflammatory infiltrate" "Acute serous inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1642.jpg" -"1643" "In addition to the granuloma, what other feature is prominent in the surrounding tissue?" "Hyperplastic glandular structures" "Fibroblastic proliferation with collagen deposition" "Mixed population of inflammatory cells including lymphocytes and neutrophils" "Adipocytes with large clear vacuoles" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1643.jpg" -"1644" "Observing the image, which statement best describes the distribution of melanin pigment in the tissue?" "The melanin is exclusively located within the basal layer and not in the underlying connective tissue" "The melanin is evenly dispersed throughout all layers of the epithelium and the connective tissue" "The melanin is present in the basal layer and scattered throughout the underlying connective tissue" "The melanin is most abundant in the stratum granulosum and less in the basal layer" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1644.jpg" -"1645" "Which feature in this image is indicative of a possible glandular malignancy?" "The presence of large, open spaces within the tissue." "The stroma surrounding the cells is heavily populated with cells." "Cells are loosely packed with no apparent structure." "Gland-like structures with small lumens are observed." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1645.jpg" -"1646" "Based on the appearance of the nuclei within the cells, which of the following features is consistent with the histopathology image provided?" "Monomorphic nuclei with uniform size and shape" "Anisokaryosis with varied nuclear sizes" "Hyperchromatic nuclei with high DNA content" "Hypochromatic nuclei with decreased DNA content" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1646.jpg" -"1647" "When examining the stroma surrounding the gland-like structures, what alteration is suggested by the histopathology image?" "Dense collagenous stroma typically seen in fibrosis" "Reduced stroma often associated with invasive malignancy" "Increased stroma indicative of a benign process" "Edematous stroma suggestive of an inflammatory response" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1647.jpg" -"1648" "In the provided tissue section, where does the transition to mature bone tissue appear to occur?" "At the bottom of the image, where the tissue has a dense and fibrous appearance." "In the region where the cell morphology becomes irregular and disorganized." "Just below the proliferative zone (PZ), where cells show signs of enlargement and are less densely packed." "At the top of the image, where cells with clearly visible nuclei are organized in a columnar fashion." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1648.jpg" -"1649" "Which morphological feature is prominent in the parasitic eggs seen in this tissue sample?" "A lateral spine" "A terminal spine" "A hooked embryo" "An operculum" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1649.jpg" -"1650" "How would you describe the staining characteristics of the nuclei within the inflammatory cells surrounding the parasitic eggs?" "Basophilic, small, and dense" "Basophilic, small, and vesicular" "Eosinophilic, large, and vesicular" "Eosinophilic, small, and dense" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1650.jpg" -"1651" "What pattern of growth best describes the organization of the carcinoma cells seen in this view?" "Linear strands of uniform cells" "Nests of cells in a 'jigsaw' pattern" "Well-organized acinar structure" "Cribriform pattern with punch-out lumens" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1651.jpg" -"1652" "Based on the staining pattern, what is the primary localization of the protein of interest within the cells?" "Cell membrane" "Extracellular matrix" "Cytoplasm" "Nucleus" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1652.jpg" -"1653" "Based on the microscopic features, what is the most likely nature of the lesion?" "Intermediate grade malignant neoplasm" "Well-differentiated malignant neoplasm" "Benign neoplasm with organized structure" "Non-neoplastic inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1653.jpg" -"1654" "What does the presence of pink-staining, fibrillar material between the cells suggest?" "Robust angiogenesis" "Accumulation of extracellular matrix proteins" "Necrosis within the tissue" "Desmoplastic reaction" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1654.jpg" -"1655" "What can be inferred about the cells' nuclei from the microscopic image?" "Uniformly small and hypochromatic" "Large with ring-like nucleoli" "Hyperchromatic with marked pleomorphism" "Varied sizes with normochromatic staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1655.jpg" -"1656" "Which type of epithelial cells can be identified in the upper right quadrant of the image?" "Gastric foveolar epithelium" "Squamous epithelial cells" "Transitional epithelium" "Ciliated columnar epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1656.jpg" -"1657" "Identify the type of cells with eosinophilic cytoplasm and centrally placed round nuclei predominantly found in the lower region of the image." "Endocrine cells" "Chief cells" "Goblet cells" "Parietal cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1657.jpg" -"1658" "Based on the nuclear characteristics observed, which description best fits the chromatin pattern in these cells?" "The chromatin is evenly dispersed with small inconspicuous nucleoli" "The chromatin pattern is dense and irregular with hyperchromatic nuclei" "The chromatin shows a fine granular distribution without clumping" "There is a homogenous chromatin pattern with distinct nuclear membranes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1658.jpg" -"1659" "Identify the most likely nature of the oval structures found within the lamina propria, as indicated by arrows in the image." "Crypt abscesses" "Parasitic eggs" "Fungal spores" "Mucus-producing goblet cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1659.jpg" -"1660" "Based on the epithelial characteristics seen in the image, which region is most likely to represent regenerative epithelial changes?" "Regions where the epithelium appears thicker and shows a darker staining pattern" "Areas with uniform villous projections into the lumen" "Regions where the lineage of muscularis mucosae is readily apparent" "Areas where the epithelium is thinner and paler-staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1660.jpg" -"1661" "What feature best characterizes the central structure consistent with a blood vessel in this image?" "Broad, irregular-shaped elements resembling non-septate hyphae" "Presence of multiple septate hyphae" "Well-defined smooth muscular wall encircling the lumen" "Regularly spaced endothelial cell nuclei lining the lumen" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1661.jpg" -"1662" "What type of inflammatory cellular infiltrate is seen immediately surrounding the blood vessel?" "Predominantly eosinophils with crystalloid bodies" "Uniform lymphoid follicles with reactive germinal centers" "Dense collection of mononuclear cells consistent with chronic inflammation" "Dense collection of cells with varying sizes and darker staining nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1662.jpg" -"1663" "What type of nuclear alteration is primarily observed in the follicular cells in this image indicative of a neoplastic process?" "Multinucleation" "Nuclear grooves" "Hyperchromasia" "Macronucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1663.jpg" -"1664" "Based on the structural organization visible in the image, which of the following best describes the arrangement of the thyroid follicular cells?" "Uniform follicular structures" "Palisading peripheral cells" "Spherically arranged microfollicles" "Disrupted follicular architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1664.jpg" -"1665" "Analyzing the stromal features in the provided image, what can be observed about the stromal component?" "Stromal lymphocytic infiltrate" "Scant stromal component" "Abundant myxoid stroma" "Dense fibrotic stroma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1665.jpg" -"1666" "Based on the observed staining pattern in the microscopic image, which marker could be primarily demonstrated by the red staining?" "Hematoxylin" "Eosin" "Cytokeratin" "Vimentin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1666.jpg" -"1667" "Evaluating the cellular morphology in the tissue sample, what is the predominant shape of the atypically-stained cells?" "Cuboidal" "Round" "Squamous" "Spindle-like" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1667.jpg" -"1668" "Considering the nuclei of the red-stained cells, what is their appearance based on the staining intensity?" "Varied sizes with different staining intensities" "No visible nuclei" "Uniformly small and lightly-stained" "Large and darkly-stained" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1668.jpg" -"1669" "Considering the staining pattern, what can be inferred about the diagnostic procedure used in this sample?" "Hematoxylin and eosin stain indicating acute inflammation" "Oil Red O stain showing lipid accumulation" "PAS stain highlighting carbohydrate macromolecules" "Melanoma cocktail stain showing positivity around cell membranes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1669.jpg" -"1670" "What can be inferred about the cellularity within the glomerulus based on the microscopic image?" "Decreased, suggesting atrophy" "Increased due to inflammatory infiltrate" "Normal, without evidence of increased cellularity" "Increased due to mesangial or endothelial cell proliferation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1670.jpg" -"1671" "Considering the appearance of the mesangial regions in the image, which of the following best describes their condition?" "Revealing significant matrix accumulation" "Exhibiting mesangial expansion" "Indicating severe mesangial sclerosis" "Showing normal amount of matrix" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1671.jpg" -"1672" "Looking at the multinucleated giant cell in the image, what is the arrangement of the nuclei within the giant cell?" "The nuclei are overlying each other in multiple layers" "The nuclei are arranged in a haphazard manner throughout the cytoplasm" "The nuclei are arranged in a circle at the center of the cell" "The nuclei are arranged at the periphery of the cell, forming a horseshoe-like pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1672.jpg" -"1673" "Considering the morphology of the cells present in this tissue section, which type of body tissue is most likely depicted?" "Nervous tissue" "Muscle tissue" "Epithelial tissue" "Adipose tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1673.jpg" -"1674" "Considering the cytoplasmic features of the cells, how would you characterize the cytoplasmic to nuclear ratio?" "High cytoplasmic to nuclear ratio with abundant cytoplasm" "Variable cytoplasmic to nuclear ratio with inconsistent cytoplasmic volume" "Moderate cytoplasmic to nuclear ratio with reasonable cytoplasmic presence" "Low cytoplasmic to nuclear ratio with scant cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1674.jpg" -"1675" "What is the likely nature of the intracellular inclusions seen within the erythrocytes?" "Heinz bodies" "Basophilic stippling" "Howell-Jolly bodies" "Malarial parasites" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1675.jpg" -"1676" "How does the targeted immunostaining of the cells appear in relation to the cellular nuclei?" "The staining is congregated around the nucleus in each cell" "The staining is absent near the nucleus and present at the periphery of the cytoplasm" "The staining is diffusely distributed throughout the cytoplasm with no relation to the nucleus" "The staining is selectively present in the nucleus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1676.jpg" -"1677" "How does the smooth muscle layer appear in this histological section when compared to a healthy small airway?" "Replaced by adipose tissue" "Enlarged, suggesting hypertrophy" "Appears fragmented and disorganized" "Reduced in size, indicating atrophy" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1677.jpg" -"1678" "What does the connective tissue surrounding the small airway demonstrate in this image?" "Dense appearance with elongated nuclei" "Significant fat deposition" "Presence of elastin fibers" "Inflammatory cell infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1678.jpg" -"1679" "What is the predominant shape of the epithelial cells observed in the tissue section?" "Spheroid" "Spindle-like" "Squamous" "Columnar to Cuboidal" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1679.jpg" -"1680" "Based on the image, what can be inferred about the consistency of the antigen expression in the epithelial cells?" "Increased expression towards the lumen" "Non-existence expression throughout" "Homogeneous expression throughout" "Decreased expression towards the lumen" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1680.jpg" -"1681" "What prominent nuclear feature do the cells in this image display?" "Inconspicuous nucleoli" "Multilobulated nuclei" "Hyperchromatic nuclei" "Cartwheel chromatin pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1681.jpg" -"1682" "What staining characteristic is visible in the cytoplasm of the cells in this image?" "Basophilic cytoplasm staining blue or purple" "Amphophilic cytoplasm showing both basophilic and eosinophilic properties" "Neutrophilic cytoplasm without strong staining affinity" "Eosinophilic cytoplasm staining red or pink" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1682.jpg" -"1683" "In the Papanicolaou-stained cytological inset, what is the nuclear characteristic indicated by the white arrow?" "Hyperchromasia" "Nuclear pseudoinclusions" "Binucleation" "Nuclear pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1683.jpg" -"1684" "Which of the following hematopoietic lineage precursors are absent from the field shown in this bone marrow aspirate image?" "Megakaryocytic precursors" "Erythroid precursors" "Lymphoid precursors" "Myeloid precursors" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1684.jpg" -"1685" "Which cell type in this image exhibits a 'band-shaped' nucleus?" "Erythroid cells" "Immature granulocytes" "Mature granulocytes" "Megakaryocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1685.jpg" -"1686" "Based on the staining pattern and cellular morphology, which cells in this image are possibly characteristic of erythroid cells in different stages of maturation?" "Cells with irregular cell borders and abundant cytoplasm" "Cells with a more condensed chromatin pattern" "Cells with large, round nuclei" "Cells with segmented nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1686.jpg" -"1687" "What is the predominant staining characteristic of the larger cells with open nuclei in the microscopic image?" "Basophilic cytoplasm" "Acidophilic cytoplasm" "Neutrophilic cytoplasm" "Eosinophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1687.jpg" -"1688" "What can be inferred about the smaller cells with dark, dense nuclei scattered amongst the larger cells in the image?" "They are signifying active mitosis" "They are indicative of immature cell stages" "They represent mature erythroid cells" "They are likely undergoing apoptosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1688.jpg" -"1689" "Considering the vascular structures present in the image, which feature is apparent?" "There is no evidence of vascular space invasion" "There is lymphovascular invasion by irregular cell clusters" "Vascular spaces are devoid of any red blood cells" "Endothelial cell lining of vascular spaces is intact and well-defined" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1689.jpg" -"1690" "What feature is indicative of abnormal keratinocyte differentiation in this tissue sample?" "Psammoma bodies" "Multinucleation" "Keratin pearls" "Rosette formations" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1690.jpg" -"1691" "What histological feature might suggest this tissue section shows invasive behavior?" "The presence of a fibrous and densely packed tissue area" "A less structured arrangement of the tissue on one side of a boundary" "A distinct boundary separating two tissue types or cell populations" "Uniformity in the cellular organization" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1691.jpg" -"1692" "How would you describe the cytoplasmic features of the cells in this tissue section?" "Vacuolated cytoplasm" "Abundant basophilic cytoplasm" "Abundant eosinophilic cytoplasm with granules" "Scant eosinophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1692.jpg" -"1693" "Based on the immunohistochemical staining pattern observed in the image, which cellular component is most likely being indicated by the arrows?" "Nuclei" "Cell membrane" "Cytoplasm" "Extracellular matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1693.jpg" -"1694" "Considering the size and morphology of the nuclei visible in the image, how would you describe the variation among the cells?" "The nuclei display moderate variation, with differences in shape but not size." "The nuclei display moderate variation, with differences in size but not shape." "The nuclei vary widely, with some being twice as large as others." "The nuclei show little to no variation in size or shape." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1694.jpg" -"1695" "Based on the epithelial cell layer lining the luminal structures, which characteristic feature of the cells can be identified?" "Single-layered with uniform nuclei" "Stratified with surface keratinization" "Multi-layered with basal hyperchromatic nuclei" "Single-layered with columnar appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1695.jpg" -"1696" "Assessing the stroma in this tissue section, what type of microscopic features can be observed?" "Dense fibrous tissue with abundant vascular channels" "Loose connective tissue with edematous changes" "Atrophy with scanty vascular channels" "Adipose infiltration with minimal vascularization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1696.jpg" -"1697" "Based on the histological features observed in the peripapillary area, which of the following statements is correct?" "There is a disruption of the normal tissue architecture" "There is evidence of significant fibroblast proliferation" "There is an apparent lymphocytic infiltration" "There is a notable increase in keratinized stratified squamous epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1697.jpg" -"1698" "What histopathological feature is NOT evident in the visible tissue section?" "Lymphocytic infiltration" "Presence of an epithelial layer" "Hyperplasia of the epithelial layer" "Maintenance of overall tissue architecture" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1698.jpg" -"1699" "What is the predominant staining pattern observed in the nuclei of the cells in the upper layer of the epithelium?" "Homogeneous light staining" "Peripheral condensation of chromatin" "Strong and darkly stained" "Absence of staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1699.jpg" -"1700" "Evaluating the nuclei of the cells in the basal layer, what can be deduced about their proliferative activity compared to that of the cells in the upper (surface) layer?" "Basal layer cells have less proliferative activity" "Basal layer cells show complete absence of proliferative activity" "Basal layer cells have similar proliferative activity" "Basal layer cells have higher proliferative activity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1700.jpg" -"1701" "Based on the cellular orientation and morphology, what is the most likely pattern of growth observed in this microscopic field?" "A well-demarcated tubular pattern" "An organoid nesting pattern" "A palisading arrangement" "A haphazard, storiform pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1701.jpg" -"1702" "Considering the staining characteristics and extracellular components, what kind of matrix is predominantly present in the tissue sample?" "Dense acellular collagen bundles" "Abundant myxoid stroma" "Homogeneous, lightly stained ground substance" "Eosinophilic, collagenous extracellular matrix" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1702.jpg" -"1703" "What can be inferred about the structural integrity of the vasa recta in relation to the surrounding tissue based on the image?" "Disruption around the structures of the vasa recta suggests a granulomatous reaction" "There is no noticeable damage or disruption around the vasa recta" "The vasa recta demonstrate significant dilation and increased luminal area" "The vasa recta are thickened and exhibit hyperplasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1703.jpg" -"1704" "Based on the morphology seen under the microscope, what is the most likely identity of the structures indicated by the yellow arrow?" "Nonseptate hyphae" "Septate hyphae" "Bacterial colonies" "Dense fibrous connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1704.jpg" -"1705" "What notable feature is observed in the cytoplasm of the cells in this microscopic image?" "Cytoplasm with multiple vacuoles" "Abundant eosinophilic cytoplasm" "Prominent granules in the cytoplasm" "Clear cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1705.jpg" -"1706" "Considering the arrangement of cells in the microscopic image, how are the cells organized?" "Forming glandular structures" "Arranged in a sheet-like pattern" "Organized in a well-defined structural pattern" "Loosely arranged without a well-defined structural pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1706.jpg" -"1707" "Based on the morphology of the nuclei, how would you describe their appearance?" "Small and pyknotic" "Ovoid and monomorphic" "Elongated and described as 'cigar-shaped'" "Round and vesicular" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1707.jpg" -"1708" "What is the predominant structural feature of the connective tissue in this synovial tissue section?" "Reticular connective tissue" "Dense regular connective tissue" "Dense irregular connective tissue" "Loose connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1708.jpg" -"1709" "What characteristic is commonly observed in the nuclei of the chondrocytes in this image?" "Clear nucleoplasm with prominent nucleoli" "Multiple nucleoli within each nucleus" "Presence of nuclear inclusions" "Dense chromatin distribution" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1709.jpg" -"1710" "Considering the appearance of the extracellular matrix surrounding the chondrocytes under this magnification, how does it most accurately appear?" "Eosinophilic with fibrillar structures" "Basophilic and relatively homogeneous" "Heterogeneous with visible collagen fibers" "Containing distinct granules and vesicles" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1710.jpg" -"1711" "How can the thyroid follicles in this image be characterized?" "Disrupted and atrophic with decreased or absent colloid" "Normal with uniform colloid distribution" "Cystic with mucinous colloid" "Hyperplastic with abundant colloid" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1711.jpg" -"1712" "What tissue can be observed at the bottom of the image?" "Adipose tissue" "Dense irregular connective tissue" "Striated muscle fibers" "Hyaline cartilage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1712.jpg" -"1713" "Based on the shape of the nuclei in the cells observed in the bone marrow tissue, which description is most accurate?" "All nuclei are elongated with a spindle-like appearance." "The nuclei are polymorphic with marked anisokaryosis." "All nuclei are uniform in size and shape without any variation." "The nuclei are round to oval with some variation in size and shape." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1713.jpg" -"1714" "What does the presence of dark-staining nuclei in cells surrounding the tubules suggest?" "Increased mitotic activity" "Hyperchromasia indicative of malignancy" "An inflammatory cell infiltrate" "Pyknosis due to cell death" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1714.jpg" -"1715" "Based on the cellular features observed in the microscopic image, which nuclear characteristic is predominantly exhibited by the thyroid cells?" "Uniform nuclear contour without irregularities" "Multiple prominent nucleoli within each nucleus" "Nuclear grooving with irregular outlines" "Highly condensed chromatin with no visible clearing" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1715.jpg" -"1716" "Based on the overall cellularity of the bone marrow tissue observed in the image, which of the following is the prevailing state?" "Normocellular" "Hypercellular" "Acellular" "Hypocellular" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1716.jpg" -"1717" "What feature of erythroid precursors is suggested by the darker-staining cells with round to oval nuclei in the image?" "A high nucleus-to-cytoplasm ratio" "Lower density of cytoplasmic granules" "Increased cytoplasmic basophilia" "The presence of a prominent nucleolus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1717.jpg" -"1718" "Based on the cellular morphology observed, which type of cell dominates the presented tissue section?" "Hepatocytes" "Erythrocytes" "Adipocytes" "Neuron-like cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1718.jpg" -"1719" "What feature found in the image might suggest that the observed glial cells are not the predominant cell type in this field of white matter?" "The clear layering and patterning of the cells" "The small, darker-staining nuclei without visible cytoplasm" "The large, round to oval cell bodies with prominent nucleoli" "The presence of a pink fibrillar matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1719.jpg" -"1720" "What is the nucleus-to-cytoplasm ratio observed in the majority of cells within this image?" "Moderate nucleus-to-cytoplasm ratio" "Low nucleus-to-cytoplasm ratio" "No discernible nucleus-to-cytoplasm ratio" "High nucleus-to-cytoplasm ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1720.jpg" -"1721" "Assessing the airway profile within the lung tissue sample, what is the indication of the structural changes observed in the lumen?" "There is airway narrowing indicative of constriction or obstruction" "There are signs of mucosal ulceration typical of necrotizing inflammation" "There is airway dilation suggestive of emphysematous changes" "There is a presence of luminal polypoid growth consistent with tumors" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1721.jpg" -"1722" "What characteristic feature does the surface layer of the tissue display in the provided image?" "Wavy, layered structure" "Thick, hypercellular layering" "Disorganized, neoplastic proliferation" "Smooth, uniform lining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1722.jpg" -"1723" "Based on the staining characteristics observed in the image, which staining method is most likely used?" "Coomassie Brilliant Blue" "Masson's Trichrome stain" "Giemsa stain" "Periodic Acid–Schiff (PAS) stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1723.jpg" -"1724" "In the intact hepatocellular areas, what cellular morphology is most consistently observed?" "Clear cytoplasm with no visible nuclei" "Small, hyperchromatic nuclei" "Large multilobated nuclei" "Dark purple nuclei and pink cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1724.jpg" -"1725" "Based on the cellular characteristics shown, which type of staining technique is most likely used in this image?" "Hematoxylin and Eosin stain" "Giemsa stain" "Papanicolaou stain" "Wright's stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1725.jpg" -"1726" "Based on the cellular morphology visible in the image, what kind of cellular differentiation can be identified?" "Squamous cell differentiation with keratinization" "Neuroendocrine differentiation with rosette formation" "Adipocytic differentiation with signet ring features" "Myeloid differentiation with Auer rods presence" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1726.jpg" -"1727" "What type of additional cells can be identified in the background of the tissue sample?" "Hepatocytes with binucleate cellular features" "Myocytes with cross striations" "Inflammatory cells among the atypical cells" "Endothelial cells lining a blood vessel" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1727.jpg" -"1728" "Based on the cellularity surrounding the blood vessel in the image, what is the most likely histological finding?" "Eosinophilic infiltration" "Lymphoid aggregates" "Granulomatous inflammation" "Neutrophilic infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1728.jpg" -"1729" "What feature is indicated by the white arrows in the dermis?" "Extravasation of red blood cells" "Melanophages with melanin deposits" "Dermal nevus cells" "Suprabasal clefting" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1729.jpg" -"1730" "Which description best matches the nuclear characteristics of the cells in this image?" "Pale nuclei with a single small nucleolus" "Small, dark nuclei without visible nucleoli" "Homogeneous chromatin and inconspicuous nucleoli" "Hyperchromatic nuclei with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1730.jpg" -"1731" "Analyzing the cellular response present around the eosinophilic material, what type of reaction is suggested by the morphology of the surrounding cells?" "Normal regenerative activity" "Neoplastic transformation" "Foreign body inflammatory response" "Granulomatous inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1731.jpg" -"1732" "What prominent structure can be observed in the center of this tissue section?" "A glandular structure" "A necrotic core" "A collagenous stroma" "A keratin pearl formation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1732.jpg" -"1733" "Based on the nuclear features observed in this image, what level of differentiation does the neoplasm likely exhibit?" "Well differentiation" "Cannot be determined" "Moderate differentiation" "Poor differentiation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1733.jpg" -"1734" "The brown staining in the nuclei of several cells within this image indicates the presence of which antigen?" "Ki67" "P53" "Estrogen receptor" "HER2/neu" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1734.jpg" -"1735" "What cellular morphology is displayed by the cells in this stained tissue sample?" "Columnar" "Squamous" "Spindle-shaped" "Cuboidal" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1735.jpg" -"1736" "Based on the immunohistochemical staining pattern observed in the tubular structures, what is the primary localization of the target antigen within the cells?" "Nuclear localization" "Uniform distribution throughout the cell" "Membranous localization" "Cytoplasmic localization" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1736.jpg" -"1737" "Based on the histological features observed in the image, which cellular alteration is indicated by a granular eosinophilic appearance in the hepatocytes?" "Ballooning degeneration" "Steatosis" "Apoptosis" "Granular degeneration" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1737.jpg" -"1738" "What does the darker eosinophilic staining observed near the central vein suggest?" "Sinusoidal congestion" "Lymphocytic infiltration" "Necrosis" "Fibrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1738.jpg" -"1739" "What histopathological feature is indicated by the arrow in the image?" "Fibroadenoma" "Squamous cell carcinoma" "Lipoma" "Adenocarcinoma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1739.jpg" -"1740" "What is the predominant nuclear feature identifiable in the cells with signet-ring appearance?" "Multinucleation" "Pleomorphism" "Macronucleoli" "Uniformity in size and shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1740.jpg" -"1741" "Based on the tissue morphology, which aspect of the gland-to-stroma ratio is most apparent?" "An increased gland-to-stroma ratio" "A decreased gland-to-stroma ratio" "An equivalent gland-to-stroma ratio" "An absent gland-to-stroma ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1741.jpg" -"1742" "What type of staining technique is likely used to achieve the coloration of the extracellular matrix in this microscopic image?" "Periodic acid-Schiff (PAS) staining" "Alcian blue staining" "Hematoxylin and eosin (H&E) staining" "Masson's trichrome staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1742.jpg" -"1743" "Identify the feature that is absent in this image, which would otherwise suggest a pathological process at play." "Inflammatory infiltrate" "Eosinophil infiltration" "Fibroblast proliferation" "Neovascularization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1743.jpg" -"1744" "What is the morphology of the deposits seen within the renal tubules?" "Uniform, dark pigmented, intracellular aggregates" "Uniform, eosinophilic, intracellular deposits" "Heterogeneous, eosinophilic, extracellular deposits" "Heterogeneous, dark pigmented, intraluminal deposits" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1744.jpg" -"1745" "Analyzing the intercellular space visible in the image of this smooth muscle tissue, how would you describe the quantity of the extracellular matrix?" "Abundant extracellular matrix separating the cells" "Minimal to no visible extracellular matrix with cells tightly packed together" "Moderate amount of extracellular matrix with some separation between cells" "Extensive hyalinization separating the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1745.jpg" -"1746" "Based on the pattern of the granulomatous structures observed, how would you describe their distribution in the tissue?" "Isolated and well-circumscribed granulomas" "Confluent pattern with merging granulomatous structures" "Disorganized and diffuse distribution without clear granulomatous structures" "Sparsely distributed granulomas with clear boundaries" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1746.jpg" -"1747" "Which staining technique is suggested by the purple coloration of the cells' cytoplasm and nuclei?" "Wright stain" "Periodic Acid-Schiff stain" "Giemsa stain" "Hematoxylin and Eosin stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1747.jpg" -"1748" "What is the morphology of the intraluminal contents in the renal tubules?" "Small, evenly-dispersed granules" "Scattered lipid droplets" "Large, eosinophilic crystalloid structures" "Homogeneous proteinaceous casts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1748.jpg" -"1749" "What is the density of the interstitial cells in the image?" "Sparse with normal cellularity" "Mildly increased cellularity" "Complete absence of cells" "Marked hypercellularity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1749.jpg" -"1750" "What can be inferred about the tubules seen in the image?" "The tubules show signs of hydropic change" "The tubules have calcifications within their luminal spaces" "The tubules contain eosinophilic material" "The tubules demonstrate villous atrophy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1750.jpg" -"1751" "What aspect of the cells in this image is indicative of their epithelioid nature?" "The lighter colored connective tissue stroma" "The presence of scattered inflammatory cells" "The cells' granular eosinophilic cytoplasm" "The nesting arrangement of cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1751.jpg" -"1752" "What does the architecture of the tissue, as observed in the histological specimen, suggest?" "Abundant extracellular matrix and stromal tissue" "High degree of organization and regular structures" "Disorganized structure with loss of normal tissue architecture" "Presence of mature, differentiated cell types" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1752.jpg" -"1753" "Based on the brown membranous and cytoplasmic staining observed in the image, which antigen is predominantly expressed by the clusters of cells?" "Anti-CD20" "Anti-CD3" "Anti-synaptophysin" "Anti-cytokeratin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1753.jpg" -"1754" "By examining the cellular architecture in this image, what type of tissue is most likely represented?" "Lymphoid tissue" "Adipose tissue" "Squamous epithelium" "Muscular tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1754.jpg" -"1755" "What do the multiple small, round to oval nuclei scattered throughout the tissue most likely correspond to?" "Endothelial cells" "Macrophages" "Neutrophils" "Spindle cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1755.jpg" -"1756" "Based on the presence of large, abnormal cells with multiple nuclei, which of the following best describes the likely pathological process visible in the tissue?" "High-grade dysplasia" "Acute inflammation" "Benign neoplastic growth" "Chronic inflammation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1756.jpg" -"1757" "Based on the cytological features visible in the image, which cell types might the larger cells with lighter-staining cytoplasm represent?" "Neutrophils" "Hepatocytes" "Megakaryocytes" "Follicular cells of the thyroid" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1757.jpg" -"1758" "Based on the microscopic image provided, what is the predominant staining pattern of the connective tissue surrounding the tubular structures?" "Mostly blue with sparse pink regions" "Alternating bands of blue and pink" "Primarily pink with some areas of blue" "Uniformly blue with no pink areas" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1758.jpg" -"1759" "What do the arrows in the microscopic image most likely indicate?" "They signify regions with suspected neoplastic activity" "They are pointing to regions of necrosis within the tissue" "They mark the areas with dilated blood vessels suggestive of hyperemia" "They highlight the areas where the basement membrane is disrupted" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1759.jpg" -"1760" "Considering the overall tissue organization in the image, what is conspicuously absent?" "Normal glandular differentiation" "Evidence of mitotic figures" "Adipose tissue interspersed between neoplastic cells" "Reticular fibers supporting tissue architecture" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1760.jpg" -"1761" "What feature is indicated by the arrow pointing to the center of the small blood vessel?" "Neutrophilic infiltration" "Lipid-rich atheroma" "Hyaline arteriolosclerosis" "Eosinophilic thrombus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1761.jpg" -"1762" "What type of cell arrangement is primarily seen surrounding the duct-like structure (indicated by the arrow)?" "Lymphocytes with large nuclei and minimal cytoplasm" "Squamous epithelial cells with intercellular bridges" "Adipocytes with large vacuoles" "Fibroblasts with spindle-like morphology" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1762.jpg" -"1763" "How would you describe the nuclei of the cells surrounding the duct-like structures?" "Dark-staining and relatively uniform in size" "Hyperchromatic and pleomorphic" "Clear with peripheral margination of chromatin" "Vesicular with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1763.jpg" -"1764" "Considering the architectural pattern and the cellular morphology present, what is the most likely histopathological feature identified by the arrow?" "Neoplastic proliferation of acinar cells" "Formation of a squamous epithelial pearl" "Lymphocytic infiltration around a duct" "Fibrotic stroma with collagen deposition" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1764.jpg" -"1765" "Based on the cellular arrangement and morphology observed in the epithelium, which of the following best describes the organization of the cells?" "Tightly packed squamous cells in a honeycomb pattern" "Single layer of cells with uniform size" "Multi-layered rows of columnar cells" "Multilayered polyhedral cells in stratified layers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1765.jpg" -"1766" "Based on the immunostaining pattern observed, what is the likely stage of the cell cycle for the majority of cells in this image?" "G0 (Resting phase)" "M (Mitosis phase)" "Early G1 (Pre-DNA synthesis phase)" "S (DNA synthesis phase)" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1766.jpg" -"1767" "Based on the staining intensity and distribution, which proliferative index range do these cells most likely fall under?" "26-50%" "0-25%" "51-75%" "76-100%" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1767.jpg" -"1768" "What does the morphology of the cells depicted in the image most likely represent?" "Cells with high nucleus-to-cytoplasm ratio and monomorphic nuclei" "Round to polygonal cells with eosinophilic cytoplasm and prominent nucleoli" "Uniform cells with small, regular nuclei and abundant cytoplasm" "Spindle-shaped cells with hyperchromatic nuclei and scant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1768.jpg" -"1769" "Based on the organization of the cells, what pattern is implied in this microscopic view?" "Dense, sheet-like arrangement with no distinct architectural pattern" "Pseudoalveolar pattern with clusters of cells forming round lobules" "Glandular architecture with columnar cells forming ducts" "Palisading arrangement of nuclei at the periphery of the lobules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1769.jpg" -"1770" "Assessing the morphology of the structures indicated by the arrows, which feature would you expect to find in normal tissue that is absent or altered in this field of view?" "Regularly aligned blood vessels with uniform endothelial cells" "Smooth muscle layer consistently surrounding the blood vessels" "Orderly arranged connective tissue fibers" "Blood vessels surrounded by densely packed irregular cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1770.jpg" -"1771" "What type of inflammatory cells predominate in the infiltrate presented in this histological section of dermis?" "Eosinophils" "Lymphocytes" "Macrophages" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1771.jpg" -"1772" "What is the predominant cellular morphology observed in this tissue section?" "Spheroid cells with hyperchromatic nuclei" "Columnar cells with basal oval nuclei" "Cuboidal cells with central round nuclei" "Spindle-shaped cells with elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1772.jpg" -"1773" "Based on the staining characteristics, what can be inferred about the expression of the intermediate filament protein within these cells?" "Cells express vimentin consistently throughout the tissue" "Cells predominantly express cytokeratin" "Cells variably express different intermediate filament proteins" "Cells do not express any intermediate filament proteins" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1773.jpg" -"1774" "Within the dermis, what can be inferred about the cell collection seen?" "It is a well-circumscribed collection of cells forming a nodule" "It is a vascular proliferation" "It is an abscess filled with neutrophils" "It is a diffuse infiltration of neoplastic cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1774.jpg" -"1775" "Based on the image, what do the dark-staining spots within the epidermal layer suggest?" "Melanin granules" "Apoptotic bodies" "Normal nucleus" "Keratohyalin granules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1775.jpg" -"1776" "In the dermis layer of the skin tissue shown in the image, what do the white arrows primarily point to?" "Dermal fibroblasts" "Adipocytes" "Hair follicles" "Dilated capillaries" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1776.jpg" -"1777" "What is the predominant architectural pattern observed within the cells of the provided microscopic image?" "Disorganized, individual cell infiltration" "Gland-like structures with well-formed lumina" "Solid sheets and nests" "Papillary and cobblestone arrangement" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1777.jpg" -"1778" "Within the provided image, are there any regions indicative of hyalinization?" "Dark purple areas throughout the tissue representing hyalinization" "Pink-stained extracellular matrix areas correspond to hyalinization" "There are extensive areas of clear cell change, indicative of hyalinization" "No areas show characteristics of hyalinization" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1778.jpg" -"1779" "Based on the PAS staining, which component of the renal tissue is highlighted in the pink-magenta tones?" "Red blood cells" "Glomerular basement membrane" "Interstitial fibrous tissue" "Tubular cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1779.jpg" -"1780" "Upon examining the glomerulus in this PAS-stained section of renal tissue, what observation can be made about the glomerular basement membrane (GBM)?" "GBM appears slightly thickened" "GBM shows evidence of splitting or lamination" "GBM is significantly thinned" "GBM is markedly thickened" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1780.jpg" -"1781" "What can be inferred about the mesangial areas based on this image of the PAS-stained renal tissue?" "They display significant hypercellularity" "The mesangial areas seem to have a normal appearance" "There is mesangiolysis present" "There is an apparent increase in mesangial matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1781.jpg" -"1782" "Based on the staining characteristics and cellular morphology, what is the most likely identity of these cells in the tissue?" "Osteocytes" "Adipocytes" "Schwann cells" "Hepatocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1782.jpg" -"1783" "What can be suggested by the uniformity of the staining and the high cellularity of the tissue?" "High expression of a specific marker" "Degenerative tissue changes" "Presence of an inflammatory infiltrate" "Low metabolic activity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1783.jpg" -"1784" "Based on the nuclear features of the follicular cells, which of the following characteristics are evident?" "The nuclei are large with irregular contours and prominent nucleoli" "The nuclei are hyperchromatic and show prominent nucleoli" "The nuclei are small, round, and show dense chromatin" "The nuclei show clearing with nuclear grooves and overlapping" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1784.jpg" -"1785" "Observing the colloid content within the follicles, how would you describe its appearance?" "The colloid is fragmented and vacuolated" "The colloid is pale and less dense" "The colloid appears abundant with a foamy texture" "The colloid is dense and deeply eosinophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1785.jpg" -"1786" "What histopathological feature is notably present in the clusters of densely packed cells in this tissue section?" "Russell bodies" "Keratin pearls" "Reed-Sternberg cells" "Psammoma bodies" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1786.jpg" -"1787" "Based on the cellular morphology and tissue architecture visible in this image, what is the most likely diagnosis?" "Squamous cell carcinoma" "Basal cell carcinoma" "Melanoma" "Adenocarcinoma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1787.jpg" -"1788" "Analyzing the cell density and arrangement in the stroma, which feature is most consistent with the observed tissue morphology?" "Abundant lymphocytic infiltration" "High vascular component" "Dense collagenous matrix" "Loose connective tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1788.jpg" -"1789" "Based on the cellular morphology and organization in the image, what is the most likely histological process occurring?" "Acute inflammation" "Chronic inflammation" "Healing by primary intention" "Granulomatous inflammation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1789.jpg" -"1790" "Which feature in the image supports the presence of an active tissue response?" "The arrangement of collagen fibers" "The coloration of the extracellular matrix" "The presence of prominent vascular structures" "The presence of spindle-shaped fibroblasts" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1790.jpg" -"1791" "Based on the organization of the cell layers around the tubular structures, which potential diagnosis should be considered?" "Nephroblastoma (Wilms' Tumor)" "Acute Tubular Necrosis" "Renal Cell Carcinoma" "Schwannoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1791.jpg" -"1792" "Analyzing the staining patterns, what can be inferred about the tubules compared to the surrounding spindle cells?" "Tubules contain anaplastic cells" "Tubules contain cells that are more lightly stained" "Tubules show higher density of the targeted marker" "Tubules exhibit more cellular pleomorphism" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1792.jpg" -"1793" "Based on the appearance of the muscle fibers and their nuclei position in the image, which type of muscle tissue is represented?" "Cardiac muscle tissue" "Smooth muscle tissue" "Skeletal muscle tissue" "No muscle tissue present" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1793.jpg" -"1794" "Which structural component is indicated by the transverse bands across the width of the cells staining more intensely than the surrounding tissue?" "I-bands" "H-zones" "Z-lines" "A-bands" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1794.jpg" -"1795" "Based on the brown pigmentation in the image, what does it likely represent?" "Hematoxylin stain highlighting cell nuclei" "Melanin deposits within the cells" "Immunoperoxidase staining indicating a specific protein" "Eosin stain showing cytoplasmic features" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1795.jpg" -"1796" "What feature of the stroma can be assessed from this image?" "Necrotic with areas of inflammatory infiltrate" "Scant with no significant staining" "Highly fibrous with significant collagen deposition" "Abundantly myxoid with mucopolysaccharides" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1796.jpg" -"1797" "Based on the tissue architecture and vessel morphology in the image, which description most accurately fits?" "Thick-walled vessels with extensive hyalinization" "Well-formed vessel lumens with a regular endothelial lining" "Uniform vessels with smooth muscle lining in an organized pattern" "Elongated and irregularly shaped blood vessels with varying sizes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1797.jpg" -"1798" "Based on the histological characteristics, what does the pale eosinophilic staining pattern within the boxed area suggest?" "Dense lymphocytic infiltration" "Ongoing tissue necrosis with loss of cellular detail" "Active fibroblastic proliferation" "Healthy intact tissue with normal cellularity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1798.jpg" -"1799" "Based on the staining pattern, what does the extracellular matrix in this image suggest about the tissue's condition?" "Edematous changes" "Fibrosis" "Background inflammatory process" "Presence of necrotic debris" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1799.jpg" -"1800" "What feature indicates the presence of a significant immune response in this tissue section?" "The presence of spindle-shaped cells with abundant cytoplasm" "The presence of large cells with multinucleated giant cell appearance" "Numerous cells with round to oval, densely stained nuclei" "Cells with clear cytoplasm and distinct cell boundaries" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1800.jpg" -"1801" "Based on the cellular morphology observed in this image, what can you infer about the architecture of the original tissue?" "The tissue has a well-organized squamous epithelial layer" "The tissue demonstrates a well-formed glandular structure" "The architecture of the tissue is effaced with no discernible pattern" "The tissue exhibits a papillary architecture" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1801.jpg" -"1802" "Based on the image, how would you describe the cellular arrangement within the tissue?" "Organized with well-defined glandular structures" "Oriented in parallel bundles" "Disorganized with no clear pattern" "Arranged in circular rosette formations" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1802.jpg" -"1803" "Considering the morphology of the cells and the presence of certain structures, what is the potential origin of these cells?" "Hematopoietic origin with evidence of blood cell precursors" "Neural origin characterized by neurofibrillary matrices" "Epithelial origin with glandular differentiation" "Mesenchymal origin with spindle-shaped morphology" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1803.jpg" -"1804" "Based on the microscopic characteristics, what type of collagen fiber arrangement is predominantly seen around the cystic space?" "Elongated, wavy fibers in a dense and irregular pattern" "Regularly arranged, parallel bundles" "Randomly dispersed with no specific alignment" "Organized in a concentric, whorled pattern" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1804.jpg" -"1805" "What can be inferred about the cellular composition of the cystic lesion based on the histological image?" "The cyst is densely packed with erythrocytes" "The cystic space is filled with inflammatory cells" "The cyst contains numerous epithelial cells" "The cyst is acellular, lacking any cellular material" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1805.jpg" -"1806" "What does the pink or red staining that predominantly characterizes the background matrix in this image most likely represent?" "Mucin-rich glandular secretion" "Smooth muscle fibers" "Dense regular collagenous tissue" "Hyaline cartilage matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1806.jpg" -"1807" "What is the predominant morphological feature of the positively stained cells indicated by the arrow?" "Round with centralized nuclei" "Spindle-shaped with elongated nuclei" "Columnar with apical nuclei" "Cuboidal with basal nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1807.jpg" -"1808" "Considering the glandular structures that exhibit acinar arrangements, what is the characteristic feature of their nuclei based on the immunohistochemical stain?" "The nuclei are lightly stained and located peripherally" "The nuclei are heavily stained and seem to overlap with the cytoplasm" "The nuclei are unstained and have clear boundaries with the cytoplasm" "The nuclei are small and densely stained, appearing distinct from the cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1808.jpg" -"1809" "Regarding the granular layer of the epidermis in this skin section, which description aligns with the histological findings?" "Presence of large, dark-staining granules in the cells" "Lacking keratohyalin granules and visibly atrophic" "Featuring normal keratinocyte maturation with small granules" "Completely absent, indicating a dermatological disorder" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1809.jpg" -"1810" "In which image can you observe monolayered aggregation of cells with prominent nuclear staining and a high nuclear-to-cytoplasmic ratio?" "Image (d)" "Image (a)" "Image (c)" "Image (b)" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1810.jpg" -"1811" "Which image shows cells with marked brown staining indicative of the presence of a chromogen linked to an immunostain?" "Image (a)" "Image (d)" "Image (c)" "Image (b)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1811.jpg" -"1812" "Based on the morphology observed, which type of cellular infiltration is predominantly present within the interstitial spaces?" "Macrophagic infiltration" "Eosinophilic infiltration" "Neutrophilic infiltration" "Basophilic infiltration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1812.jpg" -"1813" "Considering the tightly packed cellular organization in the image, what is the most likely explanation for the minimal extracellular space seen?" "Inflammatory cell infiltration" "Normal tissue architecture" "Fibrotic changes" "Edematous changes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1813.jpg" -"1814" "In the provided image of the bladder tissue, the nuclei of which layer stain blue to purple with the H&E technique and appear elongated?" "Umbrella cells" "Detrusor muscle" "Urothelium" "Extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1814.jpg" -"1815" "Upon examination of the histological image, the urothelium displays how many layers of cells?" "Two cell layers" "A single cell layer" "No discernible cell layers" "Multiple cell layers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1815.jpg" -"1816" "In the analysis of the muscle tissue section, which pattern best describes the areas where the pathology is more prominent?" "Areas with uniformly distributed nuclei" "Regions with increased basophilic staining" "Regions with increased eosinophilic staining" "Areas with decreased eosinophilic staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1816.jpg" -"1817" "What is the nature of the top layer of tissue evident in the microscopic image?" "Pseudostratified ciliated columnar epithelium" "Keratinized stratified squamous epithelium" "Transitional epithelium" "Non-keratinized stratified squamous epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1817.jpg" -"1818" "In the presented image, what do the vacuolated structures with peripheral nuclei most likely represent?" "Adipocytes" "Hepatocytes" "Ductal carcinoma cells" "Schwann cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1818.jpg" -"1819" "What does the brown staining pattern in the cells mostly represent?" "Red blood cells" "Nuclear features" "Cytoplasmic proteins" "Extracellular matrix components" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1819.jpg" -"1820" "What does the staining pattern of the tissue suggest about the possible use of immunohistochemical techniques in the preparation of this slide?" "Presence of multiple different stains indicating a panel of antibodies" "Diffuse positive reaction in the cytoplasm of tumor cells" "Focal positive reaction in a small subset of tumor cells" "No evidence of immunohistochemical staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1820.jpg" -"1821" "In regards to the appearance of the nuclei within the cells, what is the most appropriate description?" "Small, dense nuclei with occasional prominent nucleoli" "Monomorphic nuclei with regular, round shapes" "Highly pleomorphic nuclei with irregular contours" "Hyperchromatic nuclei with increased mitotic figures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1821.jpg" -"1822" "Based on the observed staining characteristics, what stain is likely to have been used in preparing this slide?" "Periodic acid-Schiff (PAS)" "Giemsa" "Hematoxylin and eosin (H&E)" "Acid-fast bacillus (AFB)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1822.jpg" -"1823" "Considering the high nucleus-to-cytoplasm ratio and the presence of numerous smaller, darkly stained particles within the cells, what could these features suggest?" "Reactive lymphocytes" "Normal red blood cells" "Healthy leukocytes" "Viral inclusions" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1823.jpg" -"1824" "Judging by the cellular clustering and morphology, what type of pathological process could be represented in this image?" "Inflammatory reaction" "Viral infection" "Benign neoplastic proliferation" "Granulomatous disease" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1824.jpg" -"1825" "What is the dominant histological feature observed in the glomerulus?" "Uniform capillary distribution without any hypercellularity" "Extensive mesangial matrix accumulation" "Uniformly thin glomerular basement membranes" "Segmental changes characterized by hypercellularity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1825.jpg" -"1826" "What is the characteristic cell type surrounding the vascular structures?" "Adipocytes" "Erythrocytes" "Lymphocytes" "Neutrophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1826.jpg" -"1827" "Based on the cellular morphology and arrangement, what condition is absent in the image?" "Granulomatous inflammation" "Lymphatic vascular ectasia" "Malignancy" "Acute inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1827.jpg" -"1828" "Based on the cellular morphology, which type of staining technique appears to have been used in this microscopic view?" "Giemsa stain" "Gram stain" "Oil Red O stain" "Acid-fast stain" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1828.jpg" -"1829" "Considering the shape and characteristics of the majority of cells in the image, what is the most likely identification of these cells?" "Muscle cells" "Erythrocytes" "Lymphocytes" "Neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1829.jpg" -"1830" "What is the most likely process indicated by the surrounding cellular infiltrate?" "Granulomatous inflammation" "An acute inflammatory response" "Chronic inflammation" "Benign neoplastic proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1830.jpg" -"1831" "Considering the staining characteristics seen in area B, which immunohistochemical marker would likely confirm the suspected cell type?" "S100 protein, indicating nerve sheath origin" "CD34, suggestive of vascular endothelial lineage" "Chromogranin, consistent with neuroendocrine cells" "Desmin, indicative of muscle cell differentiation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1831.jpg" -"1832" "Based on the immunohistochemical staining observed in this microscopic view, which cellular component is predominantly labeled?" "Nuclei" "Cytoplasm" "Extracellular matrix" "Cell membrane" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1832.jpg" -"1833" "The pink and purple coloration of the tissue in the image suggests which type of staining technique?" "Wright's stain" "Periodic acid-Schiff stain" "Giemsa stain" "Hematoxylin and eosin stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1833.jpg" -"1834" "Based on the staining pattern, which molecular component are the brown-stained structures most likely representing in this image?" "Cytoplasmic enzymes" "Extracellular matrix proteins" "Cell surface receptors" "DNA/RNA hybridization signal" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1834.jpg" -"1835" "Evaluating the overall structure and morphology, the stained tissue most closely resembles what type of organ architecture?" "Placental villi" "Skeletal muscle" "Pulmonary alveoli" "Kidney glomeruli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1835.jpg" -"1836" "How would you characterize the vascular structures present within the connective tissue stroma?" "Sinusoids with discontinuous endothelium" "Small vessels with red blood cells visible within" "Lymphatic vessels with clear spaces lacking red blood cells" "Large vessels with prominent muscular walls" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1836.jpg" -"1837" "Assessing the cellularity in the given field, which statement is most accurate?" "The distribution of the cells is uneven with dense cellular aggregates" "The cells have hypersegmented nuclei" "The cells are predominantly uniform in size" "The cells exhibit a low nucleus-to-cytoplasm ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1837.jpg" -"1838" "Based on the morphological features observed, what type of secretion mechanism is most likely associated with the glandular structures in this histological section?" "Apocrine secretion" "Holocrine secretion" "Eccrine secretion" "Merocrine secretion" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1838.jpg" -"1839" "What is the likely function of the elongated cells with denser staining around the glandular structures?" "Secreting hormones" "Providing structural support" "Insulating the glandular structures" "Contracting to expel secretions" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1839.jpg" -"1840" "What does the central eosinophilic area within the structure likely represent?" "Collagenous stroma" "Deposition of amyloid proteins" "Accumulation of adipocytes" "Areas of calcification" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1840.jpg" -"1841" "Considering the blue coloration in the cytoplasmic vacuoles, which of the following could be a likely substance accumulated within these vacuoles?" "Hemosiderin" "Glycogen" "Lipofuscin" "Melanin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1841.jpg" -"1842" "Which feature in the image is consistent with the maturation process of keratinization in an epidermoid cyst?" "The hair follicle-like structure" "The granular cells with eosinophilic cytoplasm" "The bright eosinophilic material" "The lightly stained connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1842.jpg" -"1843" "What does the presence of bright eosinophilic material adjacent to the granular layer primarily indicate?" "Accumulation of keratin characteristic of a cyst" "Inflammation and accumulation of immune cells" "Early apoptosis of the epithelial cells" "A high level of glycogen storage within the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1843.jpg" -"1844" "Based on the cellular morphology, what is the characteristic feature indicated by the arrow in the pancreatic tissue sample?" "Clear cell change indicative of lipid accumulation" "Eosinophilic cytoplasmic inclusions" "Multinucleated giant cells" "Brown pigment deposits within the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1844.jpg" -"1845" "Assessing the tissue architecture and cell distribution, what type of inflammatory response is suggested by the overall cellular pattern in the provided pancreatic tissue?" "Acute serous inflammation" "Mild granulomatous inflammatory response" "Chronic fibrosing inflammation" "Suppurative inflammation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1845.jpg" -"1846" "What is the predominant staining characteristic of the cells?" "Neutrophilic" "Acidophilic" "Basophilic" "Chromophobic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1846.jpg" -"1847" "How would you describe the arrangement of the cells viewed in this image?" "Haphazard array" "Disorganized clusters" "Whorled pattern" "Parallel bundles" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1847.jpg" -"1848" "Based on the morphology observed, which tissue type does this image most likely represent?" "Connective tissue" "Nervous tissue" "Epithelial tissue" "Smooth muscle tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1848.jpg" -"1849" "Based on the microfollicular structures observed, what type of nuclear features would be most consistent with a follicular neoplasm of the thyroid gland?" "Bi-nucleation and multinucleation with anisonucleosis" "Enlarged and pleomorphic nuclei with prominent nucleoli" "Hyperchromatic nuclei with irregular nuclear contours" "Small, uniform nuclei with inconspicuous nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1849.jpg" -"1850" "Based on the cellular morphology, what is the predominant characteristic of the cell nuclei?" "Pleomorphic and hyperchromatic" "Monomorphic and hypochromatic" "Polymorphic and euchromatic" "Uniform and anucleated" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1850.jpg" -"1851" "Considering the architecture and cellular characteristics visible in the image, which feature is least present?" "Necrosis within the cells" "Inflammatory infiltrate" "Organized glandular structure" "Collagen deposition" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1851.jpg" -"1852" "What is the staining characteristic of the cytoplasm of the glandular cells?" "Homogeneous staining of the cytoplasm" "Heterogeneous staining of the cytoplasm" "Vacuolation within the cytoplasm" "An absence of staining in the cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1852.jpg" -"1853" "Based on the cellular differentiation observed in the tissue, how would you classify the glandular structures?" "Undifferentiated glandular tissue" "Moderately-differentiated glandular tissue" "Highly-differentiated glandular tissue" "Poorly-differentiated glandular tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1853.jpg" -"1854" "Which of the following features does NOT fit the description of the connective tissue as seen adjacent to the cellular conglomerate?" "Elongated, spindle-shaped cells" "Cells arranged in a more organized, parallel fashion" "Pinkish cytoplasm" "Cells with a high nuclear-to-cytoplasmic ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1854.jpg" -"1855" "Based on the cellular morphology and arrangement, what is the best morphological assessment of the tubular structures?" "Hyperplasic tubules with excessive cell division" "Atrophied tubules with reduced cellularity" "Normal tubules with abundant mature cells" "Neoplastic tubules with disorganized growth pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1855.jpg" -"1856" "The dark purple staining of certain cell structures primarily reveals the presence of:" "Nuclei" "Extracellular matrix" "Glycogen deposits" "Cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1856.jpg" -"1857" "Analyzing the cell clusters, how would you characterize the nuclear to cytoplasmic ratio?" "Decreased with more cytoplasm than nucleus" "Inconsistent with variation among different cells" "Uniform across all cells" "Increased with more nucleus than cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1857.jpg" -"1858" "Considering the overall arrangement of cells within the clusters, how would you describe the organization?" "Disorganized arrangement" "Rosette-like pattern indicative of neuroendocrine origin" "Highly organized with a single layer of cells" "Palisading at the periphery of the clusters" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1858.jpg" -"1859" "In the inset, which histochemical staining technique is visualized and what does the color change indicate?" "Congo red indicating amyloid deposits" "Masson's Trichrome indicating fibrosis" "Jones methenamine silver indicating basement membrane thickening" "Ziehl-Neelsen indicating acid-fast bacilli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1859.jpg" -"1860" "Considering the organization of the enclosed internal content of the large structures in the tissue, which characteristic are they most likely to represent?" "Miracidia within schistosome eggs" "Malignant neoplastic cells within a tumor mass" "Sporozoite arrangement within a parasitic cyst" "Keratin pearls within a well-differentiated squamous cell carcinoma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1860.jpg" -"1861" "The surrounding cell population, primarily composed of cells with small, round nuclei and abundant pink cytoplasm, is indicative of what type of inflammatory response?" "Neutrophil-predominant acute inflammation" "Eosinophil-predominant allergic or parasitic response" "Lymphocyte-predominant chronic inflammation" "Macrophage-predominant granulomatous inflammation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1861.jpg" -"1862" "Based on the organization of the cells in this tissue sample, which growth pattern do they most likely represent?" "Solid nests" "Glandular formation" "Psammoma bodies" "Fibrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1862.jpg" -"1863" "What is the predominant characteristic of the nuclei observed in the infiltrating cells?" "Central and rounded" "Hyperchromatic and small" "Eccentrically placed" "Multilobed configuration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1863.jpg" -"1864" "What can be said about the cellular architecture in the tissue?" "Arranged in a disorganized pattern forming sheets" "Organized in lobules" "Structured in glandular formations" "Organized in well-defined nests" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1864.jpg" -"1865" "Based on the coloration and morphology, what type of staining technique is depicted in the image?" "Giemsa staining" "Periodic acid-Schiff (PAS) staining" "Masson's trichrome staining" "Immunohistochemical staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1865.jpg" -"1866" "By examining the tissue architecture, which statement is likely correct regarding the differentiation of the tissue?" "The tissue has uniform cells, implying a high degree of differentiation" "The tissue shows extensive extracellular matrix, indicating strong differentiation" "The tissue is poorly differentiated with no clear structural boundaries" "The tissue is well-differentiated with clear structural boundaries" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1866.jpg" -"1867" "Based on the cellular pattern observed in the microscopic image, which diagnosis is consistent with the histological features?" "Melanoma" "Adenocarcinoma" "Basal cell carcinoma" "Squamous cell carcinoma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1867.jpg" -"1868" "What feature within the islands can be observed upon close examination of the microscopic image that is characteristic of this type of lesion?" "Keratin pearls" "Glandular differentiation" "Small cystic spaces" "Intracellular melanin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1868.jpg" -"1869" "Analyzing the organization of the tissue architecture in the image, what can be deduced about the invasiveness of the lesion?" "The lesion has breached the basement membrane." "The lesion shows signs of irregular invasion into surrounding structures." "The lesion exhibits significant infiltration of inflammatory cells." "The lesion shows a well-differentiated boundary with the surrounding stroma." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1869.jpg" -"1870" "Within the hepatocytes, what type of inclusions can be noted and what do they likely represent?" "Purple filamentous inclusions indicative of alcoholic hyaline" "Dark blue granular inclusions indicative of viral inclusion bodies" "Brownish granular substances suggesting bile pigment deposition" "Large clear vacuoles suggesting lipid accumulation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1870.jpg" -"1871" "Based on the cellular changes seen in some hepatocytes, which of the following options best describes the specific type of injury present?" "Scattered dark pink to red, globular inclusions representing acidophil bodies" "Dark pink to red, globular inclusions representing Mallory bodies" "Periportal neutrophilic infiltration suggesting acute inflammation" "Red blood cell extravasation indicating hemorrhage" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1871.jpg" -"1872" "Based on the dark staining observed in the tissue, what cellular component appears to be highlighted?" "Endothelial cells" "Hepatocytes" "Kupffer cells" "Bile duct cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1872.jpg" -"1873" "Assessing the tissue structure, what can be inferred about the vascular architecture?" "Reduced intralobular sinusoidal capillaries" "Enhanced reticulin framework" "Prominent and hyperplastic bile ducts" "Extensive vascular proliferation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1873.jpg" -"1874" "What does the arrowhead indicate in the microscopic image?" "An area of necrosis" "A fat body cell" "A layer of the cuticle" "A non-pigmented haemocyte cluster" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1874.jpg" -"1875" "What cellular structure is prominently highlighted with specific staining in the center of the image?" "Connective tissue fibers" "Bronchiole with ciliated epithelium" "Lymph node follicle" "Blood vessel" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1875.jpg" -"1876" "Considering the overall architectural disruption shown in the image, what is the condition of the fundamental liver lobular structure?" "Uniformly hyperplastic without disruption" "Still discernible despite morphological changes" "Completely absent" "Difficult to discern due to widespread necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1876.jpg" -"1877" "What can be deduced about the state of the tubules in this tissue sample?" "There is significant dilation of the tubules" "Tubules exhibit simple cuboidal epithelium with some variation in size" "The tubules display uniform atrophy throughout the sample" "There are widespread signs of acute tubular necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1877.jpg" -"1878" "What is the predominant cytoplasmic staining pattern observable in the gastric gland cells present in the image?" "Homogeneous absence of staining in all cells" "Cytoplasmic staining with a gradient from the base to the apex of the cells" "Predominantly dark staining with areas of variable intensity" "Uniformly light staining throughout all cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1878.jpg" -"1879" "Assessing the nuclear morphology, how would you describe the nuclei of the cells in the gastric glands?" "The nuclei are mostly absent or pyknotic" "The nuclei are small, uniform, and well spaced" "The nuclei are large with prominent nucleoli and clear nuclear membranes" "The nuclei show signs of crowding and pleomorphism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1879.jpg" -"1880" "How would you describe the nuclear-to-cytoplasm ratio seen in the cells within this microscopic image?" "Moderate nucleus-to-cytoplasm ratio" "Inconsistent nucleus-to-cytoplasm ratio across all cells" "High nucleus-to-cytoplasm ratio" "Low nucleus-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1880.jpg" -"1881" "What can be inferred about the chromatin pattern within the nuclei of these cells?" "Chromatin displays a clear margination against the nuclear membrane" "Chromatin is open and finely dispersed" "Chromatin exhibits a predominantly loose and reticular pattern" "Chromatin shows consistent evenly distributed clumping" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1881.jpg" -"1882" "Based on the morphology of the nuclei, how would the variation in size and shape of the nuclei be classified?" "Polymorphic, with extreme variation in size and shape" "Anisokaryotic, with visible variation in size and shape" "Monomorphic, with uniform size and shape" "Pleomorphic, with moderate variation in size and shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1882.jpg" -"1883" "Based on the cellular arrangement and morphology, what type of epithelium can be inferred from the image?" "Squamous epithelium" "Columnar epithelium" "Glandular epithelium" "Cuboidal epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1883.jpg" -"1884" "Based on the cell morphology, what is the most likely diagnosis for this specimen?" "Basal cell carcinoma" "Ductal carcinoma in situ" "Squamous cell carcinoma" "Adenoid cystic carcinoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1884.jpg" -"1885" "What staining characteristic is predominantly observed in the mononuclear cells within this adipose tissue section?" "Nucleic acid staining with hematoxylin" "Brown cytoplasmic staining" "Perinuclear halo" "Cytoplasmic eosinophilia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1885.jpg" -"1886" "What is the morphology of the nuclei of the mononuclear cells scattered throughout this adipose tissue sample?" "Hypersegmented" "Round with prominent nucleoli" "Elongated" "Smudged" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1886.jpg" -"1887" "In Panel A of the provided image, what feature is indicated by the dense band of tissue at the bottom of the section?" "Adipose tissue" "Areolar connective tissue" "Hyalinized collagen" "Muscular tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1887.jpg" -"1888" "Identify the cellular components present within the interalveolar septa based on the staining properties in the image." "Collagen fibers stained red" "Alveolar macrophages stained light blue" "Erythrocytes stained dark purple " "Capillaries with erythrocytes stained various shades of pink" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1888.jpg" -"1889" "In the image, how does the extracellular matrix (ECM) near the atypical cells appear?" "Pale eosinophilic with a loose fibrous structure" "Deeply eosinophilic with a dense fibrous structure" "Homogeneously basophilic with a hyaline structure" "Acellular with a mucinous appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1889.jpg" -"1890" "Based on the immunohistochemical staining of the specimen, what percentage of the cells exhibit strong nuclear positivity for SOX10?" "90-100%" "30-50%" "60-80%" "10-20%" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1890.jpg" -"1891" "Based on the morphological features observed in the image, what is the nature of the nuclei within the cells of the innermost layer lining the vessel?" "Flattened with dark nuclei" "Oval with prominent nucleoli" "Multilobed with light staining nuclei" "Round and hypertrophic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1891.jpg" -"1892" "Assessing the extracellular matrix of the media in the image, what is the staining characteristic of the collagen fibers present?" "Collagen fibers appear faded and are barely visible" "Collagen fibers appear blue and clearly defined" "Collagen fibers are pink and variably stained" "Collagen fibers stain green and are predominant over other structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1892.jpg" -"1893" "What can be inferred about the cellularity of the media layer from the image?" "There is decreased cellularity in the media layer" "The media layer shows complete absence of cells" "There is no discernible change in cellularity in the media layer" "There is increased cellularity and thickening of the media layer" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1893.jpg" -"1894" "What does the brown cytoplasmic staining in several cells suggest?" "A generic counterstain without specificity" "Presence of a specific immunohistochemical marker" "Non-specific cytoplasmic staining" "Absence of any specific markers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1894.jpg" -"1895" "What is the predominant cellular morphology observed in this tissue section?" "Cuboidal cells with basal nuclei" "Polygonal cells with prominent nucleoli" "Round cells with central nuclei" "Spindle-shaped cells with elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1895.jpg" -"1896" "What does the staining pattern in the tissue section suggest?" "Patchy staining with areas of high and low intensity, indicating variable expression" "Uniform staining throughout the cells, suggesting diffuse cytoplasmic expression" "Brown staining predominantly in the nuclei, suggesting nuclear protein expression" "Brown staining throughout the tissue, indicating the presence of a specific marker" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1896.jpg" -"1897" "Based on the morphology visible in the image, the staining pattern, and nuclear characteristics, what might be concluded about the origin of these cells?" "Derived from epithelial tissue" "Derived from endocrine tissue" "Derived from mesenchymal tissue" "Derived from neural tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1897.jpg" -"1898" "In the tissue depicted, the eosinophilic background suggests the presence of what type of extracellular matrix?" "Dense irregular connective tissue" "Adipose tissue" "Fibrillary matrix" "Hyaline cartilage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1898.jpg" -"1899" "Identify the cell type based on the high cytoplasmic granularity observed in some of the cells." "Basophils with coarse, irregular granules" "Eosinophils with large granules" "Neutrophils with fine granules" "Lymphocytes with a smooth cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1899.jpg" -"1900" "Considering the small, purple-stained, oval-shaped structures seen inside and outside of cells, which are the most likely diagnoses?" "Amastigotes from Leishmania parasites" "Nitrogenous waste depositions" "Haemozoin from malaria parasites" "Hepatic lipid accumulation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1900.jpg" -"1901" "In terms of cellularity and stromal composition, how does the tissue in the image appear?" "Hypercellular with areas of overlapping cells and interspersed collagen fibers" "Hypercellular with dense collagenous stroma" "Paucicellular with abundant myxoid stroma" "Hypocellular with prominent adipocyte infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1901.jpg" -"1902" "What type of epithelium is observed surrounding the hollow space that is likely part of a tubular structure?" "Simple columnar epithelium" "Stratified squamous epithelium" "Ciliated pseudostratified columnar epithelium" "Transitional epithelium" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1902.jpg" -"1903" "What type of connective tissue is suggested by the pink-stained matrix observed in the glandular and other connective tissue regions of the image?" "Loose connective tissue" "Reticular connective tissue" "Adipose tissue" "Dense irregular connective tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1903.jpg" -"1904" "Identifying characteristics of glandular activity, what feature is indicated by the yellow arrow in the image?" "Serous-secreting cells" "Mucous-secreting cells" "Lipid-rich sebaceous cells" "Sweat-secreting eccrine cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1904.jpg" -"1905" "What specific cell type or feature might one expect to find at the tissue near the black arrow, yet is not clearly distinguishable in this specific image?" "Melanocytes" "Keratinized cells" "Cilia" "Goblet cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1905.jpg" -"1906" "What can be deduced about the cytoplasm of the cells from the image?" "It appears abundant and contains multiple granules" "It shows strong eosinophilic staining typical of muscle tissue" "It is lightly stained and does not show much detail" "It is densely stained and obscures the nuclear details" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1906.jpg" -"1907" "What does the presence of macrophages containing ingested cellular debris in the image suggest about the tissue's condition?" "Regenerative activity" "Metabolic storage disease" "Acute inflammation" "Immune clearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1907.jpg" -"1908" "What pattern of staining best describes the immunohistochemistry observed in the cells?" "Cytoplasmic staining" "Nuclear staining" "Diffuse staining throughout the cell" "Membrane-bound staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1908.jpg" -"1909" "Considering the distribution of the specific antigen targeted by the primary antibody, what would be the most likely intensity pattern of staining across the cells?" "Uniform and intense across all cells" "Variable intensity with some cells showing no staining" "Gradient intensity from one side of the tissue section to the other" "Intermittent, patchy staining across cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1909.jpg" -"1910" "What distribution pattern of immunohistochemical staining is primarily observed in this image?" "Extracellular matrix" "Membranous" "Cytoplasmic" "Nuclear" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1910.jpg" -"1911" "Judging by the pattern of the staining, which antigen expression pattern is likely in the cells from this tissue sample?" "Absence of expression and no staining noted" "Strong expression with uniform staining intensity throughout the tissue" "Focal expression with staining limited to certain areas" "Heterogenous expression with variable staining intensity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1911.jpg" -"1912" "Based on the characteristics observed in the keratinocytes of the epidermal layer, which condition is most likely indicated?" "Spongiosis" "Acantholysis" "Keratinocyte necrosis" "Hyperkeratosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1912.jpg" -"1913" "Based on the Grocott's methenamine silver staining technique used, how would you classify the contrast between the fungal organisms and the background tissue?" "Low contrast with similar coloring to background" "Variable contrast with fungal organisms being inconsistently stained" "High contrast with fungal organisms appearing lighter" "High contrast with fungal organisms appearing darker" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1913.jpg" -"1914" "Based on the eosinophilic (pink) staining, what is the most likely composition of the areas with increased pink staining?" "Areas of dense collagen deposition" "Zones of fibrinoid necrosis within the dermal layer" "Regions of keratinization within the epithelium" "Accumulations of lipids within adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1914.jpg" -"1915" "What does the presence of elongated cells with spindle-shaped nuclei likely indicate in this tissue section?" "Presence of smooth muscle cells in the vessel walls" "Keratinocytes showing signs of acantholysis" "Adipocytes accumulating within the subcutaneous tissue" "Fibroblasts typically found within the dermal layer" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1915.jpg" -"1916" "How can the condition of the mesangial areas in this renal tissue be described?" "Marked by fibrous cap formation" "No evidence of hypercellularity or sclerosis" "Having hypercellularity with increased mesangial matrix" "Sclerotic and over-expanded" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1916.jpg" -"1917" "Based on the histological features observed, what morphological abnormality appears to be absent in the hepatocytes of this liver specimen?" "Mallory bodies" "Fibrosis" "Necrosis" "Lipid accumulation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1917.jpg" -"1918" "What feature of the hepatic architecture is notably absent in the provided field of view of this liver tissue sample?" "Portal vein branches" "Central veins" "Interlobular bile ducts" "Hepatocyte plates" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1918.jpg" -"1919" "Identify the cell type characterized by bilobed nuclei in this image." "Eosinophils" "Macrophages" "Basophils" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1919.jpg" -"1920" "Based on the arrangement and structure, what type of additional tissue component can be identified within the fibrous stroma?" "Skeletal muscle tissue" "Vascular endothelium" "Glandular epithelial structures" "Neural ganglia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1920.jpg" -"1921" "How would you describe the nuclei of the epithelial cells lining the glandular structures?" "Darkly stained and organized in an acinar arrangement" "Small and eccentrically located" "Darkly stained and organized in a pseudostratified manner" "Large and centrally located" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1921.jpg" -"1922" "Based on the histopathological features observed, which of the following characteristics is NOT evident in this image of tissue?" "Uniform round nuclei with small nucleoli" "Thin-walled blood vessels with red blood cells" "Abundant clear cytoplasm" "Disorganized tissue architecture" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1922.jpg" -"1923" "In this micrograph, areas with eosinophilic cytoplasm are visible. What might these areas indicate?" "Necrosis within the tumor" "Areas with a higher density of organelles" "Fibrotic tissue surrounding the neoplasm" "Areas of hemorrhage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1923.jpg" -"1924" "Based on the tissue morphology, which cell type predominantly constitutes the 'N' region?" "Epithelial cells" "Erythrocytes" "Adipocytes" "Collagen fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1924.jpg" -"1925" "The extracellular components visible in the image predominantly show features indicative of what condition?" "Dense fibrosis with abundant pink-staining collagen" "Necrotic tissue with a lack of cellular components" "Inflammatory infiltrate with numerous immune cells" "Edema with abundant clear spaces" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1925.jpg" -"1926" "Analyzing the cellular arrangement in the image, which description best fits the observed tissue organization?" "Dyscohesive clusters with anaplastic features" "Sheet-like arrangement without stromal invasion" "Glandular formation with luminal structures" "Palisading arrangement around a fibrovascular core" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1926.jpg" -"1927" "Considering the morphologic features of the cells, what is the likely level of pleomorphism?" "Moderate pleomorphism with some variability" "Absent or minimal pleomorphism with uniform cells" "High pleomorphism with marked variability in size and shape" "Low pleomorphism with occasional size variation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1927.jpg" -"1928" "Based on the size and shape of the nuclei, what can be inferred about the population of cells within this tissue section?" "Predominantly mature lymphocytes" "Predominantly epithelioid cells" "Predominantly neutrophils" "Predominantly eosinophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1928.jpg" -"1929" "Based on the histology of the gastric tissue, what is the morphology of the surface epithelial cells?" "Cuboidal shape with basal nuclei" "Tall, columnar shape with abundant cytoplasm" "Squamous shape with abundant eosinophilic cytoplasm" "Flattened shape and not demonstrating the typical tall, columnar appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1929.jpg" -"1930" "What does the cellular morphology of the underlying connective tissue in the image suggest?" "The connective tissue is denser than the overlying epithelial layer" "The connective tissue appears less dense than the overlying epithelial layer with visible nuclei" "The connective tissue contains myofibroblasts indicative of fibrosis" "The connective tissue is characterized by an increased number of adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1930.jpg" -"1931" "What feature marked by the star indicates the peripheral boundary of the glandular structure?" "Fibrovascular stroma" "Muscularis mucosae" "Glandular lumina" "Gastric pits" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1931.jpg" -"1932" "What does the arrow in the image likely point to?" "A blood vessel" "A glandular lumen" "A gastric pit" "Muscularis mucosae" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1932.jpg" -"1933" "Based on the cell morphology, what staining technique was likely used in the preparation of this slide?" "Periodic acid-Schiff (PAS)" "Hematoxylin and Eosin (HE)" "Giemsa stain" "Acid-fast stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1933.jpg" -"1934" "What are the smaller, round anucleate structures observed in the background of the image?" "Platelets" "Mitotic figures" "Microorganisms" "Red blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1934.jpg" -"1935" "What does the brownish cytoplasmic staining signify in the context of an immunohistochemical analysis?" "Positive staining for a particular antigen" "Necrosis within the tumor tissue" "Non-specific background staining" "Collagen deposition within the stroma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1935.jpg" -"1936" "Based on the immunolabeling pattern, which cerebellar layer is likely to have the highest expression of the targeted antigen?" "Molecular layer" "Purkinje cell layer" "White matter tracts" "Granular layer" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1936.jpg" -"1937" "What cellular feature is indicated by the white arrow in the microscopic image?" "A mitotic figure" "Lipid droplet inclusion" "Bizarre multinucleated cell" "Apoptotic body" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1937.jpg" -"1938" "In the context of lymphocytic infiltration within the underlying connective tissue, which arrangement can be observed in this image?" "Sparse and disorganized lymphocytes" "Band-like arrangement of lymphocytes" "Absence of lymphocytic infiltrate" "Follicular arrangement of lymphocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1938.jpg" -"1939" "Focusing on the epithelial layers, what is the observed state of cellular differentiation?" "Hyperkeratotic differentiation" "Glandular differentiation" "Normal differentiation with distinct cell layers" "Poor differentiation with loss of cellular stratification" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1939.jpg" -"1940" "Based on the morphology of the cells present within the stroma, which type of cells can be identified?" "Eosinophils" "Squamous epithelial cells" "Nucleated red blood cells" "Synovial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1940.jpg" -"1941" "Analyzing the architecture of the tissue in the image, which feature is indicative of a pathological process?" "Dense and hyperchromatic stromal nuclei" "Loss of the normal compact stromal structure" "Presence of uniform, small-sized villi" "Well-organized villous structures" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1941.jpg" -"1942" "What type of branching pattern is observed in the fungal hyphae in this histopathological image?" "Random branching" "Right-angled branching" "Dichotomous branching" "Parallel branching" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1942.jpg" -"1943" "Identify the eosinophilic (pink-staining) structure seen centrally in the image" "Hair shaft" "Skeletal muscle fibers" "Elastic fibers" "Collagen fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1943.jpg" -"1944" "What is the most appropriate interpretation of the scattered inflammatory cells within the connective tissue?" "Indicative of chronic inflammation" "Displaying cellular pleomorphism" "Normal feature of this tissue type" "Suggestive of acute inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1944.jpg" -"1945" "Analyzing the uniformity of the cells depicted, what can be inferred about the cellular population?" "The uniformity implies a benign neoplastic process with little variation" "The cellular population exhibits some variation in size and shape that could suggest a neoplastic process" "The uniformity suggests a high level of cellular differentiation" "The cells appear reactive with uniform hyperplasia throughout" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1945.jpg" -"1946" "Regarding the cytoplasmic staining seen in the image, what color predominates in the cell cytoplasm, suggesting the nature of the staining?" "A heterochromatic staining pattern showing high variability in staining intensity" "A bluish staining, indicating a basophilic nature of the cytoplasm" "A consistent eosinophilic hue throughout the cytoplasm" "A clear cytoplasm with minimal staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1946.jpg" -"1947" "Based on the cellular morphology, which of the following is a characteristic feature of the darkly stained roughly spherical objects in the liver tissue?" "Bile pigment accumulation" "Degenerated hepatocytes" "Micro-abscess formation" "Lipid-laden macrophages" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1947.jpg" -"1948" "Based on the staining characteristics, which cell type is most likely represented by the cells with lobulated nuclei?" "Basophils" "Eosinophils" "Lymphocytes" "Neutrophil polymorphs" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1948.jpg" -"1949" "Based on the cytoplasmic staining observed in the large cells, what is the most likely molecular target of the immunohistochemical stain?" "Hemoglobin" "Melanin" "Glycogen" "Lipofuscin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1949.jpg" -"1950" "Based on the staining pattern observed, which cellular component primarily exhibits strong positive staining?" "Mitochondria" "Nuclei" "Extracellular Matrix" "Cytoplasm and Cell Membrane" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1950.jpg" -"1951" "The pale areas within the brown-stained cytoplasm suggest which of the following about the immunohistochemical staining result?" "Accumulation of secretory products" "Absence of staining in the nuclei" "Deposition of extracellular substances" "Presence of intracellular lipid droplets" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1951.jpg" -"1952" "What can be inferred about the extracellular matrix based on this H&E stained image?" "The extracellular matrix is homogeneously distributed" "There is a lack of extracellular matrix" "The extracellular matrix appears basophilic" "The extracellular matrix appears eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1952.jpg" -"1953" "What is the predominant pattern of the immunohistochemical staining observed in the cells?" "Membranous" "Extracellular matrix" "Nuclear" "Cytoplasmic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1953.jpg" -"1954" "In differentiating potential neoplastic changes in the glandular epithelium, which finding is least suggestive of a benign process?" "Hyperchromatic nuclei with an irregular arrangement of glandular cells" "Increased nuclear to cytoplasmic ratios and prominent nucleoli" "Glandular cells with basally oriented nuclei and more cytoplasm" "Dense eosinophilic stroma with a normal arrangement of collagen fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1954.jpg" -"1955" "In the tissue sample presented, what does the minimal presence of extracellular matrix most likely suggest?" "Fibrotic tissue response" "Normal tissue architecture" "Diffuse infiltrative process" "Mature connective tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1955.jpg" -"1956" "Based on the nuclear characteristics visible in the cells, which assessment best aligns with the image's presentation?" "Nucleoli are absent in the majority of cells" "The nuclei show a high level of pleomorphism" "There is homogeneity of the nuclear shape and size" "Most nuclei appear pyknotic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1956.jpg" -"1957" "Based on the observed coloration within the image, which staining technique is likely to have been used to highlight the tissue structures?" "Wright's stain" "Periodic acid-Schiff (PAS) stain" "Hematoxylin and eosin (H&E) stain" "Masson's trichrome stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1957.jpg" -"1958" "What is the predominant cellular morphology observed in this immunohistochemically stained tissue sample?" "Spindle-shaped cells" "Squamous cells" "Round to ovoid cells" "Columnar cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1958.jpg" -"1959" "Based on the cellular morphology observed in this renal tissue section, which description best fits the nuclei of the cells?" "The nuclei show variability in shape, with prominent staining." "The nuclei are small and inconspicuous with minimal staining." "The nuclei are hyperchromatic and show significant pleomorphism." "The nuclei are uniformly round with even staining throughout." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1959.jpg" -"1960" "What does the dense eosinophilic (pink) area in the image most likely represent?" "Osseous metaplasia" "Hyaline cartilage" "Necrotic tissue" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1960.jpg" -"1961" "The basophilic (purple) area with cells that have larger nuclei could be most suggestive of what kind of tissue?" "Neoplastic tissue" "Skeletal muscle" "Lymphoid tissue" "Mature bone" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1961.jpg" -"1962" "How would you describe the nuclear features of the cells in this histological sample?" "Bland chromatin" "Elevated mitotic rate" "Significant pleomorphism" "Hyperchromasia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1962.jpg" -"1963" "What can be inferred about the vessel walls adjacent to the thrombus in the lung tissue section?" "They are unstained and thus transparent." "They show a darker, basophilic staining." "They exhibit lighter, eosinophilic staining." "They possess a similar eosinophilic staining as the thrombus." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1963.jpg" -"1964" "What tissue component is likely to be represented by the slightly eosinophilic tissue surrounding the seminiferous tubules?" "Leydig cells producing testosterone" "The basal lamina of the seminiferous tubules" "Endothelial cells from blood vessels" "Sertoli cells supporting the germ cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1964.jpg" -"1965" "What is the predominant feature observed in the endothelial cells lining the blood vessels in this tissue section?" "The cells display hyperplasia" "The cells exhibit hypertrophy" "The cells show signs of atrophy" "The cells are characteristic of dysplasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1965.jpg" -"1966" "What feature indicates the presence of a possible focal lesion within the tissue?" "Lighter, less cellular area as indicated by the arrow" "Region with monomorphic cell population" "Homogeneous pink staining without structural details" "Area with high cellularity and mitotic figures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1966.jpg" -"1967" "What is the nature of the stroma observed in the tumor tissue?" "Loose connective tissue with adipocytes" "Copious amounts of extracellular mucin" "Eosinophilic collagen fibers with a dense arrangement" "Myxoid with scattered reticular fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1967.jpg" -"1968" "Based on the membranous and cytoplasmic staining pattern observed, what can be inferred about the tissue's origin?" "The tissue likely originates from a neuroendocrine lineage." "The tissue likely originates from a squamous epithelium." "The tissue likely originates from a mesenchymal source." "The tissue likely originates from a lymphoid lineage." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1968.jpg" -"1969" "What does the counterstaining of the nuclei suggest about the staining technique used?" "It suggests the use of a Romanowsky-type stain." "It suggests the use of an immunohistochemical stain with hematoxylin counterstain." "It suggests the use of periodic acid–Schiff reaction." "It suggests the use of a silver stain technique." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1969.jpg" -"1970" "Considering the pattern of immunoexpression, which of the following markers is most consistent with the observed staining?" "GFAP, a marker for astrocytes." "Vimentin, a marker for mesenchymal cells." "Synaptophysin, a marker for neuroendocrine cells." "CD20, a marker for B lymphocytes." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1970.jpg" -"1971" "Based on the observed tissue morphology near the central vein marked with 'C', what is the most likely content of the rounded, eosinophilic intracytoplasmic inclusions within several hepatocytes?" "Glycogen deposits" "Mallory bodies" "Lipid droplets" "Bile thrombi" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1971.jpg" -"1972" "Based on the microscopic examination of the histological section, what can be inferred about the nature of the cystic structures?" "The cysts are filled with mucinous material" "The cysts contain serous fluid" "The cysts are blood-filled" "The cysts are filled with keratinous debris" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1972.jpg" -"1973" "What can be deduced about the epithelial cells surrounding the cystic structures in the histological section?" "The epithelial cells are undifferentiated" "The epithelial cells exhibit squamous differentiation" "The epithelial cells lack distinct cell boundaries" "The epithelial cells are arranged in glandular formations" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1973.jpg" -"1974" "Considering the tissue architecture shown in the image, how would you classify the organization of the cellular arrangement?" "Highly organized with uniform spacing" "Organized in gland-like structures" "Organized with rosette formation" "Disorganized with irregular spacing" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1974.jpg" -"1975" "Considering the dense cellular arrangement of the clusters and the specificity of the brown staining, which type of neoplasm is most likely present?" "Neuroendocrine neoplasm" "Squamous cell carcinoma" "Adenocarcinoma with mucinous features" "Melanoma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1975.jpg" -"1976" "Which histological stain is most likely used in this image, as inferred from the staining properties and the details visible at high magnification?" "Periodic acid-Schiff (PAS) stain" "Wright-Giemsa stain" "Haematoxylin and Eosin (H&E) stain" "Papanicolaou stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1976.jpg" -"1977" "What pattern is predominantly observed in the ductal structures within the image?" "Papillary pattern" "Solid pattern" "Cribriform pattern" "Micropapillary pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1977.jpg" -"1978" "What is the nature of the stroma surrounding the ductal structures in this image?" "Dense with significant desmoplasia" "Loose, fibrous connective tissue without significant desmoplasia" "Lymphoid infiltrate dominating the stroma" "Hyalinized and acellular" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1978.jpg" -"1979" "How do the goblet cells within the epithelial lining appear in this H&E-stained section?" "Stained uniformly with the rest of the epithelial cells" "Clear with large cytoplasm" "Dark purple-blue with small cytoplasm" "Pink with cytoplasm filled with dense granules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1979.jpg" -"1980" "Based on the cellular structures observed, what is the predominant histopathological finding in the glomerulus?" "Crescent formation" "Diffuse mesangial proliferation" "Global glomerulosclerosis" "Segmental sclerosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1980.jpg" -"1981" "Assessing the morphology of the epithelial cells in this microscopic view, what can be deduced about their appearance?" "The cells exhibit uniformity in size and shape, with small, regular nuclei." "The cells have a minimal variation in size and a lack of observable nuclei." "The cells appear highly pleomorphic with multi-nucleated giant cells." "The cells show moderate pleomorphism, with variability in size and shape." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1981.jpg" -"1982" "Based on the chromatin pattern observed in panel B, which disease process would you consider?" "Anaplastic thyroid carcinoma" "Medullary thyroid carcinoma" "Lymphocytic thyroiditis" "Follicular thyroid carcinoma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1982.jpg" -"1983" "What does the cellular distribution within the glomerulus suggest?" "Increased cellularity with cells filling the capillary lumina" "Decreased cellularity in the glomerular capillaries" "Uniform cell distribution within the glomerular capillaries" "Presence of only extracapillary cells surrounding the glomerulus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1983.jpg" -"1984" "What change in the cyst wall structure is evident in this microscopic view?" "Walls with thick layers of cellular accumulation" "Areas with less dense cellular arrangement" "Walls with increased thickness" "Walls that appear rigid and densely stained" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1984.jpg" -"1985" "Identify the regions that contain high density of nuclei and may represent a pathological process in the tissue." "Empty cyst spaces" "Patches indicated by double asterisks" "Regions marked by single asterisks" "Regions with thin cyst walls" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1985.jpg" -"1986" "What feature is indicated by the arrow in the image?" "A region of necrosis" "A sebaceous gland entrapped by neoplastic cells" "A collection of adipocytes" "A normal lymph node follicle" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1986.jpg" -"1987" "Regarding the endothelial cells lining the vascular channels, what is their morphology?" "The endothelial cells are uniformly shaped and equally spaced" "The endothelial cells are thin and well-differentiated" "The endothelial cells appear hypertrophied or hyperplastic" "The endothelial cells lack nuclear atypia" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1987.jpg" -"1988" "What does the variation in cell size and shape embedded within the eosinophilic material suggest about the nature of these cells?" "They are likely undergoing mitosis" "They could be indicative of cellular diversity" "They may be hypertrophic chondrocytes" "They may represent different stages of chondrocyte maturation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1988.jpg" -"1989" "When assessing the adipocytes within the image, how do they appear in comparison to normal marrow?" "Hyperplastic" "Atrophic" "Uniformly sized" "Hypertrophic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1989.jpg" -"1990" "In the provided microscopic image of kidney tissue, what is the primary identifier for distinguishing the renal cortex from the renal medulla?" "The renal cortex appears lighter in color due to fewer nuclei and less hematoxylin staining." "The renal cortex has smaller, more densely packed structures." "The renal medulla exhibits a darker staining pattern due to high cellular density." "The renal medulla contains more visible blood vessels compared to the cortex." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1990.jpg" -"1991" "What do the crescent-shaped white spaces within the kidney tissue image likely indicate?" "The calyces which are voids that drain into larger structures." "Accumulations of immune cells within the kidney tissue." "Areas of tissue damage or scarring." "Extensions of the renal cortex into the medulla." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1991.jpg" -"1992" "What feature best characterizes the nucleoli within the cells in this image?" "Absent nucleoli" "Multiple nucleoli per nucleus" "Small and indistinct nucleoli" "Prominent and eosinophilic nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1992.jpg" -"1993" "Regarding the tubular epithelial cells, which observation is correct?" "The majority of cells display significant hypertrophy" "The epithelial cells are predominantly atrophic or flattened" "All tubular epithelial cells are uniformly swollen, suggesting acute injury" "Most epithelial cells are consistent with normal morphology" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1993.jpg" -"1994" "Focusing on the ratio of nuclear to cytoplasmic content, which of the following best describes the cells seen in the image?" "Nuclear-to-cytoplasmic ratio not discernible" "Low nuclear-to-cytoplasmic ratio with abundant cytoplasm" "High nuclear-to-cytoplasmic ratio with reduced cytoplasm" "Balanced nuclear-to-cytoplasmic ratio with regular cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1994.jpg" -"1995" "In image B, what is the nuclear morphology of the haloed cells dispersed within the epidermis?" "Nuclei with dense chromatin clumping" "Round or hyperconvoluted nuclei" "Oval and uniform nuclei" "Nuclei with multiple nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1995.jpg" -"1996" "What is the morphological indication of epidermotropism in image B?" "Single cells notable at the rete ridges" "Clustering of cells in the dermis" "Multilayering of the stratum corneum" "Presence of cells at the tips of dermal papillae" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1996.jpg" -"1997" "Based on the image, what is the predominant characteristic of the tissue below the epithelial layer?" "Loose connective tissue with dispersed cells" "Dense, fibrous connective tissue indicating a muscular layer" "Adipose tissue with large, empty-looking cells" "Dense irregular connective tissue with random fiber orientation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1997.jpg" -"1998" "What can be inferred about the scattered oval structures within the connective tissue stroma?" "They are adipocytes indicative of fat infiltration" "They are red blood cells indicating hemorrhage" "They are ova from a parasitic infection" "They are malignant neoplastic cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1998.jpg" -"1999" "What feature is highlighted by the star symbol in the image?" "Inflammatory infiltrate" "Keratin pearls" "Dermal papillae" "Nevus cell aggregates" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/1999.jpg" -"2000" "Based on the arrow indicator, how would you describe the pleomorphism within the epithelium shown?" "Absent with uniform cell size and shape" "Evident with severe atypia" "Minimal with slight variation in size and shape" "Moderate with some cells larger than others" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2000.jpg" -"2001" "When evaluating the chromatin pattern of the nuclei in the larger nucleated cells, what observation can be made?" "The chromatin pattern appears dense and homogeneous" "The chromatin is dispersed and pale" "The nuclei contain prominent multiple nucleoli" "The chromatin forms distinct banding patterns across the nucleus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2001.jpg" -"2002" "In section A, the adipocytes within the adipose tissue are characterized by which of the following features?" "They possess a large, centrally located vacuole" "They contain large nuclei, centrally located within the cell" "They exhibit large, vacuolated structures with peripheral nuclei" "They display multiple small lipid droplets" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2002.jpg" -"2003" "What is the predominant staining pattern observed within the hepatocytes in this periodic acid-Schiff (PAS) stained liver tissue section?" "Clear cytoplasmic staining" "Dark purple nuclear staining" "Magenta cytoplasmic staining" "Blue-gray cytoplasmic staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2003.jpg" -"2004" "In this PAS-stained liver tissue sample, what is the appearance of the hepatocyte nuclei?" "Darker and rounded" "Enlarged and hyperchromatic" "Invisible due to over-staining" "Small with prominent nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2004.jpg" -"2005" "Which of the following best describes the nuclei of the cells observed in this microscopic image?" "Large and hyperchromatic with prominent nucleoli" "Small and uniform with dense chromatin" "Round with clear and well-defined cytoplasmic boundaries" "Small and uniform with inconspicuous nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2005.jpg" -"2006" "Based on the tissue staining pattern observed, which statement is true regarding the immunohistochemical expression?" "Negative nuclear expression with strong cytoplasmic staining" "Uniform expression with clear cytoplasmic boundaries" "Positive nuclear and cytoplasmic expression with a diffuse pattern" "Intense staining of the surrounding stroma with negative cell staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2006.jpg" -"2007" "Which cells in the image indicate the presence of a chronic inflammatory response?" "Cells with dense, purple-staining nuclei with scant cytoplasm" "Cells with elongated nuclei and abundant eosinophilic cytoplasm" "Cells with pink cytoplasm and central dark nuclei" "Fibers that stain pink and are sparsely distributed" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2007.jpg" -"2008" "What do the white arrows in the image most likely indicate?" "Accumulations of lymphocytes" "Areas with a high density of fibroblasts" "Concentrations of new collagen fibers" "Vacuoles within the giant cells representing ingested material" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2008.jpg" -"2009" "What morphological feature is indicated by number 1 in the liver tissue image?" "Normal hepatic architectural arrangement" "Signs of overt hepatocellular necrosis" "Typical endothelial lining around sinusoids" "Markedly dilated sinusoidal spaces" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2009.jpg" -"2010" "Analyzing the inset image stained with Elastica van Gieson (number 2), what can be observed about the fibrotic tissue present?" "Mild fibrosis indicated by blue-green strands" "Abundant elastin content within hepatic parenchyma" "Severe fibrosis with numerous thick strands" "Fibrosis is absent in the portal tract" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2010.jpg" -"2011" "What distinguishing feature can be observed in the extracellular matrix of region (a) compared to region (b)?" "The extracellular matrix in region (a) appears less densely packed than in region (b)." "The extracellular matrix in region (a) has a more haphazard orientation than in region (b)." "The extracellular matrix in region (a) exhibits a more crimped pattern than in region (b)." "The extracellular matrix in region (a) is more uniform and densely organized than in region (b)." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2011.jpg" -"2012" "Based on the observed features of the muscle fibers in the microscopic image, which of the following best describes their nuclei?" "Central and elongated" "Peripheral and spherical" "Central and spherical" "Peripheral and flattened" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2012.jpg" -"2013" "What feature is predominantly observed in the nucleation of the epithelial cells within the glands?" "Multinucleated cell presence" "Irregularities in nuclear shape and size" "Uniform nuclear size and shape" "Presence of prominent nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2013.jpg" -"2014" "What can be inferred about the nuclear to cytoplasmic ratio in the epithelial cells present in this image?" "The ratio can't be determined without additional staining" "The ratio seems to be decreased" "The ratio appears to be the same as in normal cells" "The ratio seems to be increased" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2014.jpg" -"2015" "Based on the morphological characteristics observed, which cellular arrangement is being depicted in the image?" "Regularly arranged chondrocytes in lacunae" "Disorganized clusters of lymphocytes" "Uniform sheets of epithelial cells" "Spindle-shaped and polygonal cell aggregations" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2015.jpg" -"2016" "Which pathological process is most consistent with the structural findings within this microscopic section?" "Acute cellular rejection with extensive lymphocytic infiltration" "Granulomatous inflammation with multinucleated giant cells" "Neoplastic process with possible meningothelial origin" "Inflammatory infiltrate of eosinophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2016.jpg" -"2017" "Based on the cellular morphology, what staining method has likely been used to highlight the features of the cells seen in this image?" "Periodic acid-Schiff (PAS) stain" "Ziehl-Neelsen stain" "Hematoxylin and eosin (H&E) stain" "Diff-Quik stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2017.jpg" -"2018" "What type of cellular structure is predominantly seen in the image?" "Syncytial formation" "Glandular acini" "Spindle cell proliferation" "Granuloma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2018.jpg" -"2019" "Based on the histopathological features observed, what is the most likely diagnosis for the tissue in this image?" "Adenocarcinoma" "Lymphoma" "Squamous cell carcinoma" "Melanoma" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2019.jpg" -"2020" "What is the predominant cell type shown in this microscopic image?" "Epithelial cells" "Adipocytes" "Fibroblasts" "Smooth muscle cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2020.jpg" -"2021" "Based on the arrangement of the cells in the image, which of the following features is not observed?" "The cells are arranged in a disarray pattern" "The cells display a syncytium structure" "The cells are arranged in parallel bundles" "There is extracellular matrix between the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2021.jpg" -"2022" "Which feature in this image suggests that the tissue is capable of contraction?" "All of the above" "The elongated, centrally located nuclei" "The presence of connective tissue" "The parallel arrangement of the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2022.jpg" -"2023" "What is the predominant characteristic of the cells in the area surrounding the central necrotic zone?" "Round cells with a single, central nucleus" "Spindle-shaped cells with ovoid nuclei" "Columnar cells arranged in a palisading pattern" "Cuboidal cells with central nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2023.jpg" -"2024" "Based on the cellular morphology, what level of pleomorphism is observed in this tissue section?" "Severe pleomorphism" "Moderate pleomorphism" "No pleomorphism" "Mild pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2024.jpg" -"2025" "Considering the arrangement and distinctiveness of the cells, how would you categorize the architecture of this tissue?" "Papillary structures with fibrovascular cores" "Trabecular arrangement" "Glandular with well-formed acini" "Solid sheets without distinct architecture" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2025.jpg" -"2026" "What is the predominant cell type visible on the surface epithelium in this image?" "Squamous epithelial cells" "Cuboidal epithelial cells" "Pseudostratified epithelial cells" "Columnar epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2026.jpg" -"2027" "What does the cytoplasm of the cells in the center of the image suggest?" "Abundant and eosinophilic, indicating high cytoplasmic maturation" "Scant and eosinophilic, indicative of erythroid precursors" "Scant and basophilic, indicating a higher nuclear-to-cytoplasmic ratio" "Abundant and basophilic, suggesting reactive changes within the cell" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2027.jpg" -"2028" "Considering the overall architecture and cellular organization, what is a potential interpretation of the histological pattern observed?" "Abnormal infiltration suggesting a disruption to typical bone marrow tissue organization" "Hyperplastic marrow changes with abundant megakaryocytes" "Dysplastic marrow with abnormal localization of immature precursors (ALIP)" "Normal bone marrow tissue with expected cellular differentiation and organization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2028.jpg" -"2029" "What feature within the image suggests the presence of focal congestion?" "Dilated vessels with red blood cells inside." "Presence of enlarged glands with mucous." "Areas with increased fibrous stroma." "Abundant extravasated red blood cells outside the vessels." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2029.jpg" -"2030" "Within the hepatocyte cytoplasm of this liver tissue, what histological changes are observed?" "Pyknotic nuclei" "Eosinophilic inclusions" "Clear vacuolar changes" "Amphophilic stippling" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2030.jpg" -"2031" "What type of cells can be identified increasing in number within the sinusoidal spaces in this image?" "Lymphocytes" "Hepatocytes" "Macrophages" "Neutrophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2031.jpg" -"2032" "In the histological slide provided, what pattern of cellular arrangement is observed surrounding the hair follicle that is suggestive of a radial expansion of potential tumor cells?" "Diffuse pattern" "Whorled pattern" "Nodular pattern" "Lentiginous pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2032.jpg" -"2033" "Upon examination of the histological slide under high magnification, which type of inflammatory cell is predominantly observed within the surrounding stroma?" "Lymphocytes" "Macrophages" "Neutrophils" "Eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2033.jpg" -"2034" "What abnormal morphology do the red blood cells (RBCs) in the sinusoids exhibit?" "Spherocytosis" "Target cells" "Sickling" "Anisocytosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2034.jpg" -"2035" "Based on the microscopic image, what pathology is indicated by the pale areas within the hepatocytes?" "Amyloid deposition" "Cholestasis" "Fatty change" "Hydropic degeneration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2035.jpg" -"2036" "By observing the immunohistochemical staining pattern, what is the most likely intensity of marker expression in the tumor?" "Strong expression" "No expression" "Moderate expression" "Weak expression" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2036.jpg" -"2037" "What is the staining pattern distribution observed in the cells?" "Cytoplasmic with sparing of the nuclei" "Uniform throughout the entire cell" "Nucleic with sparing of the cytoplasm" "Patchy and focal" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2037.jpg" -"2038" "In the given histological image, how do the nuclei of the acinar cells primarily appear?" "Enlarged with prominent nucleoli" "Multilobulated with conspicuous chromatin" "Pyknotic with condensed chromatin" "Vesicular with a clear perinuclear halo" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2038.jpg" -"2039" "What type of metaplasia can be observed in the provided tissue section?" "Osseous metaplasia" "Malpighian metaplasia" "Intestinal metaplasia" "Pseudostratified columnar metaplasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2039.jpg" -"2040" "Identify the dominant type of inflammatory cells infiltrating the tissue in this image." "Eosinophils" "Plasma cells" "Lymphocytes" "Macrophages" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2040.jpg" -"2041" "What morphological characteristic is indicated by the red arrow in the image?" "Presence of apoptotic bodies" "Formation of microglial nodules" "Accumulation of CD3-positive lymphocytes" "Acute neuronal injury features" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2041.jpg" -"2042" "Within the areas outlined by blue dotted lines, what pathological feature can be observed?" "Lymphocytic infiltration into the vascular walls" "Neoplastic cell clusters" "Evidence of demyelination" "Areas of ischemia and infarction" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2042.jpg" -"2043" "What does the background staining of the tissue suggest about the condition of the neural tissue?" "Predominantly healthy tissue" "Significant necrosis" "Extensive calcification" "Gliosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2043.jpg" -"2044" "What pattern of cellular architecture does the densely cellular area display in this histological image?" "Trabecular pattern" "Rosette pattern" "Antoni A pattern" "Alveolar pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2044.jpg" -"2045" "Where is the nucleus typically located within the morphology of plasma cells like the ones indicated by arrows?" "At the periphery of the cell" "Centrally placed within the cell" "Suspended within clear cytoplasmic zones" "Eccentrically placed within the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2045.jpg" -"2046" "Based on the cellular features observable in the glands, what degree of nuclear pleomorphism is present?" "Severe nuclear pleomorphism" "Mild nuclear pleomorphism" "No significant nuclear pleomorphism" "Moderate nuclear pleomorphism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2046.jpg" -"2047" "What is the morphology of the glandular structures in the histological section?" "Angulated with variation in shape and size" "Rounded with papillary projections into the lumen" "Regular, with uniform shape and size" "Circumscribed with a fibrous capsule" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2047.jpg" -"2048" "What characteristic feature of the cells suggests a viral cytopathic effect in this histopathological image?" "Cells with intranuclear inclusion bodies" "Multinucleated giant cells" "Necrotic epithelial cells" "Cells with perinuclear halos" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2048.jpg" -"2049" "Based on the cellular morphology, which is the most likely location of the tissue shown?" "The stratified squamous epithelium of the skin" "The pseudostratified columnar epithelium of the respiratory tract" "The gastrointestinal tract lining" "The simple columnar epithelium of the endocervix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2049.jpg" -"2050" "How would you classify the overall tissue architecture observed in this image?" "Highly dysplastic with complete loss of tissue architecture" "Largely normal with maintenance of tissue architecture" "Mildly dysplastic with focal disruption of tissue architecture" "Severely infiltrated by inflammatory cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2050.jpg" -"2051" "Based on the cellular arrangement observed, which type of growth pattern does this neoplastic lesion most likely represent?" "A nested growth pattern with cohesive clusters of cells" "An organoid growth pattern with well-differentiated glandular structures" "A diffuse growth pattern with a lack of cell cohesion" "A spindle cell growth pattern with elongated, mesenchymal-like cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2051.jpg" -"2052" "What aspect of the stroma can be observed in this neoplastic lesion?" "Abundant myxoid stromal content" "A rich vascular network with large blood vessels" "Dense collagen deposition giving a sclerotic appearance" "Scant stroma with thin fibrous bands" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2052.jpg" -"2053" "What is the predominant tissue architecture pattern observed in the micrograph?" "Uniform glandular structures with a single lumen" "Regular acinar structures with abundant secretion" "Atypical glandular structures with a cribriform pattern" "Well-formed papillary structures with fibrovascular cores" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2053.jpg" -"2054" "Assessing the upper part of the image, what can be said about the arrangement and morphology of the cells?" "They show glandular-like arrangements with more prominent nucleoli" "They are predominantly clear cells" "They are arranged in a sarcomatoid pattern with spindle cell morphology" "They display undifferentiated morphology with high pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2054.jpg" -"2055" "What is the approximate diameter of the prominent spherical structure identified by the arrow in the center of the image?" "100-150 micrometers" "200-250 micrometers" "50-75 micrometers" "10-20 micrometers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2055.jpg" -"2056" "Based on the cellular composition surrounding the tissue cyst wall, what is the likely type of tissue that this histological section was taken from?" "Muscular tissue" "Neural tissue" "Connective tissue" "Hepatic tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2056.jpg" -"2057" "Based on the organization of the cells in the central cluster, what type of tissue are these cells most likely from?" "Connective tissue" "Nervous tissue" "Muscle tissue" "Epithelial tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2057.jpg" -"2058" "What can be inferred about the pathology present based upon the architectural pattern observed?" "Normal tissue homeostasis" "Chronic inflammatory response" "Acute inflammatory response" "Neoplastic proliferation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2058.jpg" -"2059" "What can be inferred about the cytoplasm of the cells in this image?" "Abundant amphophilic cytoplasm" "Homogenous cytoplasm with prominent eosinophilia" "Cytoplasm with dense, darkly pigmented granules" "Clear cytoplasm with peripheral accentuation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2059.jpg" -"2060" "What feature of cellular arrangement does this image NOT display?" "Disorganized distribution of cells throughout the image" "A structured pattern typical of normal epithelial tissues" "Densely clustered cells in certain areas" "Areas with more dispersed cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2060.jpg" -"2061" "How does the matrix staining in this cartilage tissue compare to what would be expected in healthy hyaline cartilage?" "The matrix staining is similar to fibrocartilage due to increased collagen deposition." "The matrix staining is darker than normal hyaline cartilage indicating high cellularity." "The matrix is less intensely stained compared to normal hyaline cartilage suggesting myxoid degeneration." "The matrix exhibits homogenous staining typical of normal hyaline cartilage." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2061.jpg" -"2062" "What is the appearance of the cytoplasm of the cells in this image?" "Eosinophilic (pink-red)" "Amphophilic (purple)" "Neutrophilic (neutral)" "Basophilic (blue-purple)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2062.jpg" -"2063" "Based on the chromatin pattern and nuclear placement, which type of cells are most likely represented in this microscopic view?" "Plasma cells" "Neutrophils" "Monocytes" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2063.jpg" -"2064" "Based on the cell morphology, how would you characterize the differentiation of these cells?" "Moderately differentiated" "Well-differentiated" "Undifferentiated" "Poorly differentiated" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2064.jpg" -"2065" "What does the eosinophilic appearance of the background stroma suggest about the extracellular matrix in this image?" "Abundance of mucopolysaccharides" "High vascularity" "Presence of dense collagenous tissue" "Predominantly inflammatory cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2065.jpg" -"2066" "What specific cellular structure is indicated by the irregular dark lines perpendicular to the muscle fibers?" "Sarcolemma" "H-zone" "Intercalated discs" "Z-lines" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2066.jpg" -"2067" "Based on the presence of periodic cross-striations in the tissue, which type of muscle tissue is represented in this image?" "Both A and B" "Smooth muscle tissue" "Cardiac muscle tissue" "Skeletal muscle tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2067.jpg" -"2068" "Based on the distribution of the kappa light chain immunopositivity, the population of plasma cells can be described as:" "Polyclonal proliferation" "Neoplastic" "Monoclonal proliferation" "Non-reactive" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2068.jpg" -"2069" "In the microscopic image, which area demonstrates characteristics of active bone formation and remodeling?" "Area with disorganized trabecular structures" "Area with a clear, acellular matrix" "Area with homogeneously distributed cells" "Area with well-organized trabecular structures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2069.jpg" -"2070" "Based on the image, which feature does NOT correspond to the woven bone region?" "Well-ordered trabecular pattern" "Basophilic osteoid matrix" "Disorganized trabeculae" "Lacunae containing osteocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2070.jpg" -"2071" "Upon observation of the chromatin pattern within the nuclei, how would you classify it?" "Dense and clumped" "Open with easily visible nucleoli" "Finely dispersed" "Smudged with no discernible structure" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2071.jpg" -"2072" "How would you describe the appearance of the nuclei in these cells?" "The nuclei are pyknotic with little to no visible nucleoli" "The nuclei are vesicular with inconspicuous nucleoli" "The nuclei exhibit prominent nucleoli" "The nuclei are hyperchromatic with irregular borders" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2072.jpg" -"2073" "What is the predominant staining characteristic of the dense pink areas in the image?" "Presence of melanin" "Presence of elastin" "Presence of keratin" "Presence of lipofuscin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2073.jpg" -"2074" "Using the visual clues in the image, identify the process shown by the cells highlighted with arrows." "Elastophagocytosis" "Neoplastic transformation" "Apoptosis" "Karyolysis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2074.jpg" -"2075" "What aspect of the chromatin within the follicular cells can be deduced from this image?" "Chromatin with a clearing effect" "Marginated chromatin with peripheral condensation" "Hyperchromatic and smudged chromatin" "Beaded chromatin appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2075.jpg" -"2076" "What best describes the nuclei of the signet ring cells visible in this image, identified by the red arrows?" "Large and centrally positioned nuclei" "Hypochromatic and uniformly distributed nuclei" "Hyperchromatic and eccentrically located nuclei" "Small and centrally positioned nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2076.jpg" -"2077" "Considering the organization of the hepatic architecture in the provided image, what is the fibrotic change indicated by the presence of connective tissue?" "Perisinusoidal fibrosis" "Periportal fibrosis" "Bridging fibrosis" "Pericellular fibrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2077.jpg" -"2078" "Identify the mitotic activity present in the tissue sample based on the image." "Multiple mitotic figures indicating high mitotic rate" "No mitotic figures are present" "Multiple mitotic figures indicating moderate mitotic rate" "Few mitotic figures indicating low mitotic rate" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2078.jpg" -"2079" "The presence of what structures within the tissue contributes to the diagnosis of a well-differentiated neoplastic entity?" "Granulomatous inflammation" "Vascular channels" "Lymphoid aggregates" "Squamous eddies" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2079.jpg" -"2080" "What stage of mitosis is the cell labeled as being under division most likely in, based on the chromatin's condition and location?" "Anaphase" "Prophase" "Telophase" "Metaphase" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2080.jpg" -"2081" "In which panel does the basal layer of the epidermis exhibit uniform, dark brown staining?" "Panel B" "Panel C" "Panel D" "Panel A" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2081.jpg" -"2082" "Which panel indicates the presence of densely packed and irregularly distributed inflammatory cells and fibroblasts in the dermal tissue with intense brown staining?" "Panel B" "Panel D" "Panel C" "Panel A" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2082.jpg" -"2083" "In which panel does the dermal tissue show minimal brown staining with only occasional cells expressing TGF-β1?" "Panel B" "Panel A" "Panel C" "Panel D" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2083.jpg" -"2084" "What can be inferred about the central cells within the epithelial island?" "The cells are loosely arranged and more stellate or angular in shape with ample cytoplasm." "The cells are densely arranged with minimal cytoplasm and increased nuclear crowding." "The cells show clear evidence of malignancy with significant nuclear pleomorphism and multiple mitotic figures." "The cells demonstrate melanocytic features with abundant melanin pigment." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2084.jpg" -"2085" "Identify the feature marked by the blue arrow in the image." "Inflammatory infiltrate within the connective tissue stroma" "Atrophic muscle fiber" "Adipose tissue infiltration into skeletal muscle" "Normal skeletal muscle fiber with central nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2085.jpg" -"2086" "What overall condition does the muscle tissue in the image most likely represent?" "Polymyositis" "Muscular dystrophy" "Myasthenia gravis" "Amyotrophic lateral sclerosis (ALS)" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2086.jpg" -"2087" "Based on the ATPase staining at pH 4.3, what is the predominant muscle fiber type visible in this image?" "Equal distribution of Type 1 and Type 2 fibers" "Type 1 fibers" "Type 2 fibers" "Type 3 fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2087.jpg" -"2088" "Observing the muscle tissue's reaction to ATPase staining, what can be inferred about the function of the predominant fiber type shown in the image?" "They predominantly support aerobic endurance activities." "They are primarily slow-twitch fibers for rapid, forceful contractions." "They provide high endurance at low power outputs." "They are fast-twitch fibers suitable for rapid, powerful contractions." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2088.jpg" -"2089" "Based on the observed cellular characteristics, what is the most likely type of inflammatory cell infiltrate present at the site of tissue reaction?" "Basophils" "Eosinophils" "Lymphocytes" "Neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2089.jpg" -"2090" "The brown staining observed in some cells indicates what kind of process occurring within this tissue sample?" "Lipofuscin accumulation" "Necrotic cell death" "Hemorrhagic events within the tissue" "Immunohistochemical marker positivity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2090.jpg" -"2091" "Based on the morphological features observed in the lung tissue, what type of structures are present within the lumen of the bronchus?" "Mucous glands" "Cartilage rings" "Blood vessels" "Nematodes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2091.jpg" -"2092" "What is the predominant feature of the cellular morphology in this image?" "Cells with spindle-shaped morphology and elongated nuclei" "Lipid-rich vacuoles with peripherally displaced nuclei" "Multinucleated giant cells with abundant eosinophilic cytoplasm" "Large cells with hyperchromatic nuclei and a high nuclear-to-cytoplasmic ratio" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2092.jpg" -"2093" "The staining pattern in this image suggests the presence of which intermediate filament protein?" "Vimentin" "Neurofilament protein" "Cytokeratin" "Desmin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2093.jpg" -"2094" "In the image of the histological specimen, what is the nature of the matrix of the tissue shown?" "A non-mineralized connective tissue matrix" "A densely calcified bone matrix" "A pink-stained mineralized bone matrix" "A fibrinous exudate matrix" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2094.jpg" -"2095" "What is the predominant nuclear staining pattern of the cells that have a dark brown color?" "No staining in the nucleus" "Staining concentrated at the nuclear periphery" "Homogeneous staining throughout the nucleus" "Irregular nuclear staining with variation in intensity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2095.jpg" -"2096" "What does the appearance of axons within the central area of concentrically layered cells indicate?" "Presence of demyelinating disease" "Healthy, robust axonal structure" "Signs of axonal regeneration" "Possible reduction in size or atrophy of axons" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2096.jpg" -"2097" "What is the appearance of the stroma in this pathological image?" "Heavily laden with inflammatory cells and debris" "Characterized by large areas of necrosis and hemorrhage" "Loose and edematous with a translucent appearance" "Fibrous with a pinkish color" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2097.jpg" -"2098" "What is the cellular response indicated by the star in the image?" "Hemosiderin-laden macrophages" "Gomori methenamine-silver positive cells" "Lipofuscin granules" "Hypoxic muscle fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2098.jpg" -"2099" "Analyzing the inset at lower magnification, how would you describe the cellularity of the bone marrow?" "Decreased cellularity with abundant fat spaces" "Normal cellularity for the patient's age range" "Hypercellularity with numerous megakaryocytes" "Increased cellularity with less hematopoietic activity" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2099.jpg" -"2100" "In the high magnification view of the bone marrow, what is the observed state of hematopoietic activity?" "Active granulopoiesis with abundant granulocyte precursors" "Dominance of lymphopoiesis over other hematopoietic activities" "Decreased erythropoiesis and granulopoiesis with fewer precursors" "Enhanced erythropoiesis with many red blood cell precursors" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2100.jpg" -"2101" "What does the absence of hypercellularity within the glomerular capillary loops suggest about the renal pathology?" "Diabetic nephropathy" "Acute poststreptococcal glomerulonephritis" "Minimal change disease" "Membranous nephropathy" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2101.jpg" -"2102" "In the depicted glomerular capillaries, which cellular components are likely represented by the nuclei stained blue-purple?" "Podocytes and mesangial cells" "Tubular epithelial cells and endothelial cells" "Mesangial cells and endothelial cells" "Podocytes and endothelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2102.jpg" -"2103" "What is the most likely identity of the cells indicated by the arrow?" "Neutrophils" "Fibroblasts" "Lymphocytes" "Macrophages" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2103.jpg" -"2104" "What does the cytoplasmic staining characteristic observed in most of the cells in the provided image indicate?" "An increased amount of rough endoplasmic reticulum" "Accumulations of immunoglobulins" "A rich presence of mitochondria" "A high concentration of lysosomes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2104.jpg" -"2105" "What can be inferred about the location of the nuclei within the cells observed in the image?" "Nuclei are prominently located at the periphery of the cells" "Nuclei location varies drastically among the cells" "Nuclei are consistently located at the cell center" "Nuclei are not visible in the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2105.jpg" -"2106" "What does the presence of round, eosinophilic, hyaline-like inclusions within the cytoplasm and stroma of the cells in the image suggest?" "Russell bodies" "Melanin granules" "Glycogen deposits" "Viral inclusion bodies" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2106.jpg" -"2107" "Based on the nuclear staining observed in the image, which cell cycle phase are the darkly stained cells most likely in?" "Telophase" "Interphase" "Anaphase" "Prophase" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2107.jpg" -"2108" "Considering the morphology and density of cells within this tissue section, what is a likely functional characteristic of the tissue?" "Contractile activity" "Filtration and reabsorption" "Rapid gas exchange" "High synaptic connectivity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2108.jpg" -"2109" "What does the presence of eosinophilic amorphous material within the lumen suggest about the pathological process depicted in the image?" "Accumulation of lipid droplets" "The presence of fibrin associated with thrombus formation" "Glandular secretion" "Development of amyloid deposits" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2109.jpg" -"2110" "Based on the measurement scale provided, what is the approximate diameter of the seminiferous tubules shown in the histological section?" "150 µm" "50 µm" "100 µm" "200 µm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2110.jpg" -"2111" "In comparing images A and B in the provided microscopic sections of rat testicular tissue stained for Ki-67, which image demonstrates a higher frequency of cells in active proliferation?" "Image B" "Image A" "Neither image shows any proliferating cells" "Both images show equal frequency of proliferating cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2111.jpg" -"2112" "Based on the immunohistochemical staining patterns observed in images A, B, and C, which image indicates a phase of recovery in cellular proliferation after a decrease?" "Image B" "Image C" "Image A" "It is indeterminable from these images" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2112.jpg" -"2113" "Based on the morphology, which type of cells predominate the microscopic field?" "Neutrophils" "Lymphocytes" "Histiocytes" "Plasma cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2113.jpg" -"2114" "What is the characteristic pattern of the chromatin in the nuclei of the predominant cells observed?" "Hyperchromatic with irregular contours" "Vesicular with prominent nucleoli" "Cartwheel or clock face" "Diffuse and homogenous" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2114.jpg" -"2115" "Which feature best describes the architecture of the tissue surrounding the cellular nests?" "Myxoid with mucinous deposition" "Lymphoid with follicular structures" "Disorganized with infiltrative margins" "Trabecular with eosinophilic, linear strands of fibrous tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2115.jpg" -"2116" "Based on the tissue infiltration observed in the image, which area appears to be compromised by the pathological process?" "Muscle layer" "Renal parenchyma" "Adipose tissue" "Hepatic tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2116.jpg" -"2117" "Based on the cytoplasmic staining pattern, which antibody staining is likely represented in this image?" "CD34" "Ki-67" "S-100" "Vimentin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2117.jpg" -"2118" "Considering the tissue architecture and cell morphology presented in the image, which likely histopathological diagnosis can be inferred?" "Melanoma with high cellular density" "Schwannoma with Verocay body formation" "Lipoma with mature adipocyte differentiation" "Leiomyoma with smooth muscle differentiation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2118.jpg" -"2119" "Based on the morphological features observed in the epidermis, how would you classify the observed cellular alteration?" "Acanthosis" "Dyskeratosis" "Acantholysis" "Spongiosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2119.jpg" -"2120" "What is the condition of the nuclei within the epidermal cells?" "Karyorrhexis" "Karyolysis" "Micronucleation" "Enlargement" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2120.jpg" -"2121" "In which layer of the dermis are the homogeneous pink masses most likely located based on the image?" "Reticular dermis" "Papillary dermis" "Subcutaneous tissue" "Stratum corneum" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2121.jpg" -"2122" "When examining the epithelial layer in the histological section, what is the shape of the cells present?" "Cuboidal" "Spindle-shaped" "Squamous" "Columnar" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2122.jpg" -"2123" "What is the predominant characteristic of the material encasing the glomerular capillary tuft?" "Granular and eosinophilic" "Vacuolated and clear" "Homogeneous and pinkish-purple" "Fibrous and striated" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2123.jpg" -"2124" "What microscopic structure is indicated by the tubular profile lined with epithelial cells at the right lower corner of the image?" "Alveolar sac" "Pulmonary vein" "Terminal bronchiole" "Pulmonary artery" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2124.jpg" -"2125" "What best describes the density and cellularity of the tissue in the top left to center region of the image?" "Predominantly adipose tissue with significant empty spaces" "Sparsely cellular with less dense connective tissue" "Highly cellular with multiple bronchiole structures" "Homogenously dense with clusters of capillaries" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2125.jpg" -"2126" "What characteristic feature is demonstrated by the atypical cells in the image?" "Cytoplasmic inclusions resembling keratin pearls" "Syncytial arrangement of nuclei without individual cell boundaries" "Large cytoplasmic vacuoles resulting in a signet ring appearance" "Multinucleation with a rosette formation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2126.jpg" -"2127" "Based on the morphology of the cells visible in the image, which of the following is a plausible diagnosis?" "Osteosarcoma" "Signet ring cell carcinoma" "Squamous Cell Carcinoma" "Lipoma" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2127.jpg" -"2128" "What is the morphological characteristic of the nuclei in the necrotic areas of the tissue?" "Pale-staining and round to oval" "Hyperchromatic and pleomorphic" "Enlarged with prominent nucleoli" "Darkly staining and fragmented" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2128.jpg" -"2129" "When examining the right side of the image, which histological feature suggests acanthomatous changes indicative of a neoplastic process?" "Nests of cells with keratin pearls" "Isolated cell nests within extensive pink-staining connective tissue" "Monomorphic cells with small, regular nuclei and abundant cytoplasm" "Severely dysplastic cells with hyperchromatic nuclei and atypical mitotic figures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2129.jpg" -"2130" "In the image provided, what evidence of squamous differentiation can be recognized?" "Evenly dispersed chromatin within the cell nuclei" "Orange-pink areas within the cell clusters" "Cells with ovoid and basophilic nuclei" "Pink-staining connective tissue with isolated cell nests" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2130.jpg" -"2131" "What does the area of amorphous eosinophilic material inside the duct-like structure most likely indicate?" "Hyalinization" "Necrosis" "Mucinous material" "Collagen deposition" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2131.jpg" -"2132" "What is the predominant extracellular material seen in the dermal layer?" "Fibrin deposits" "Elastic fibers" "Mucin deposits" "Collagen fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2132.jpg" -"2133" "Are there any significant indications of fibroblast proliferation in the image?" "Yes, there are numerous spindle-shaped cells indicative of fibroblast proliferation" "Yes, there is an overabundance of fibroblasts compared to other cell types" "No, but fibroblast activity is not typically visible in this type of staining" "No, there is a lack of dense spindle-shaped cells which would typify fibroblast activity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2133.jpg" -"2134" "Based on the morphological features observed in the image, what type of tissue pattern is predominantly displayed by the cells surrounding the centrally located structure?" "Myxoid stroma with loose connective tissue" "Palisading neoplasm" "Dense irregular connective tissue" "Hyaline cartilage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2134.jpg" -"2135" "Considering the characteristics of the nuclei in the cells surrounding the peripheral nerve structure, which descriptive term best applies to their appearance?" "Multinucleated with anisonucleosis" "Vesicular with prominent nucleoli" "Hyperchromatic with inconspicuous nucleoli" "Pyknotic with karyorrhexis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2135.jpg" -"2136" "Based on the microscopic view of the tissue, what is the predominant type of nuclear change observed within the cells surrounding the thickened blood vessel?" "Anaplasia" "Pyknosis" "Karyolysis" "Karyorrhexis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2136.jpg" -"2137" "What can be inferred about the morphology of the surrounding tissue excluding the blood vessel?" "Maintenance of normal architecture" "A distinct honeycomb pattern representative of normal glandular tissue" "Hyperchromatic nuclei indicating high cellular proliferation" "Eosinophilic cytoplasm suggestive of acute cellular injury or death" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2137.jpg" -"2138" "Which cellular process is most prominently depicted by the cell with a large cytoplasmic area stained pink to purple containing internal material?" "Erythropoiesis" "Megakaryocyte maturation" "Neutrophil extracellular trap formation" "Hemophagocytosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2138.jpg" -"2139" "Identify the cell type most likely represented by the smaller cells with dense, purple-staining nuclei of varied shapes and visible cytoplasm." "Myelocytes" "Erythrocytes" "Lymphocytes" "Megakaryocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2139.jpg" -"2140" "Based on the morphological features observed in the epidermis, what is the predominant alteration of the keratinocytes?" "Hydropic degeneration" "Acantholysis" "Ballooning degeneration" "Spongiosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2140.jpg" -"2141" "What pathological finding is most prominently observed in the colonic mucosa based on the image?" "Increased infiltration of lymphocytes" "Adenomatous polyps" "Crypt branching and complex architecture" "Hyperplastic polyps" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2141.jpg" -"2142" "What type of muscle tissue is predominantly featured in this histological section based on the visible histological characteristics?" "Skeletal muscle tissue" "Myoepithelial tissue" "Cardiac muscle tissue" "Smooth muscle tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2142.jpg" -"2143" "Which characteristic feature of the cells arranged in a rosette-like structure can be observed under microscopy?" "Inclusion bodies" "Paracentric nuclei" "Multi-nucleation" "Centralized nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2143.jpg" -"2144" "What is the predominant staining pattern observed in the cells within this image?" "Nuclear staining" "No staining" "Cytoplasmic staining" "Membrane staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2144.jpg" -"2145" "Which staining pattern is evident in the tissue section observed under the microscope?" "Nuclear" "Extracellular matrix" "Membranous" "Cytoplasmic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2145.jpg" -"2146" "Based on the immunohistochemical staining pattern observed in the epithelial layer, what can be inferred about the expression of the target antigen?" "The target antigen is heterogeneously expressed across the epithelium." "The antigen is absent in the epithelial cells." "The target antigen shows uniform, strong expression throughout the epithelial layer." "The target antigen expression is restricted to the basal layer of the epithelial cells." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2146.jpg" -"2147" "Identify the tissue architecture based on the staining pattern and cellular arrangement provided in the image." "Pseudostratified epithelium with ciliated cells." "Simple columnar epithelium with uniform glandular cells." "Stratified columnar epithelium with robust antigen expression." "Stratified squamous epithelium with keratinized surface cells." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2147.jpg" -"2148" "Based on the morphology, which cell types are prominently featured within the small capillary in the center of this image?" "Erythroblasts and neutrophils" "Erythrocytes and thrombocytes" "Erythrocytes and neutrophils" "Erythroblasts and lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2148.jpg" -"2149" "What is the likely identity of the intracellular material within the two prominent cells observed in the capillary, based on the morphology and staining properties observed in this image?" "Lipid droplets" "Hemoglobin F" "Lipofuscin granules" "Glycogen deposits" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2149.jpg" -"2150" "In this microscopic image, what does the lightly stained extracellular matrix surrounding the cells facilitate?" "Increased microscopic contrast" "Decreased microscopic contrast" "Camouflaging of cellular details" "Impaired identification of cell types" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2150.jpg" -"2151" "Based on the morphology and staining pattern observed, which of the following cells are likely to be the neoplastic epithelial cells expressing CD20?" "The sparse, elongated cells with no brown staining" "The sparse, round cells with strong brown staining" "The densely packed, round cells with no brown staining" "The densely packed, elongated cells with strong brown staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2151.jpg" -"2152" "Considering the cellular morphology, what type of tissue can be seen on the right side of the image?" "Skeletal muscle tissue" "Adipose tissue" "Cardiac muscle tissue" "Smooth muscle tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2152.jpg" -"2153" "What is the main feature of the spindle-shaped cells observed on the left side of the image?" "Disorganized growth pattern" "Cross-striations" "Multi-nucleation" "Large cytoplasmic volume" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2153.jpg" -"2154" "What microscopic findings suggest the presence of endometrial-type stroma in this image?" "The observation of stromal cells with high nuclear-to-cytoplasmic ratios" "The presence of clear, non-staining spaces within the stroma" "A darker staining quality of the stromal cells compared to normal stroma" "A decrease in the cellular density of the stromal component" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2154.jpg" -"2155" "What is the most prominent histopathological feature in this lung tissue sample?" "Large areas of caseous necrosis" "Marked fibrotic thickening of the alveolar walls" "Abundant eosinophilic material in the alveolar spaces" "Prominent lymphoid aggregates" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2155.jpg" -"2156" "What is the predominant histological feature observed in the glomerular structures?" "Hypercellularity and inflammation" "Presence of numerous healthy cells" "Normal glomerular architecture with clear capillary loops" "Significant collagen deposition leading to sclerosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2156.jpg" -"2157" "Based on the microscopic characteristics seen in the image, what can be inferred about the functional state of the glomerular tissue?" "Slight reduction in glomerular function" "Probable loss of some glomerular function" "Probable severe reduction in glomerular function due to fibrosis" "Preservation of glomerular function" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2157.jpg" -"2158" "What can be said about the appearance of the connective tissue surrounding the sclerotic glomeruli?" "It shows an increase in eosinophilic material similar to the glomeruli" "It has a higher cell density compared to the normal glomerular tissue" "It is similarly affected by sclerosis as the glomeruli" "It appears slightly more basophilic indicating a different cellular composition" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2158.jpg" -"2159" "What is the predominant histological feature observed in the center of the pilosebaceous unit?" "Well-formed granuloma with multinucleated giant cells" "Calcification with basophilic stippling" "Necrotic debris with associated neutrophil infiltration" "Cross-sectional view of a structure with linear, darkly stained features" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2159.jpg" -"2160" "What is the characteristic appearance of the nuclei in the cells within this tissue section?" "Oval, vesicular nuclei with small nucleoli" "Small, round nuclei with inconspicuous nucleoli" "Irregular, hyperchromatic nuclei without nucleoli" "Large, round nuclei with prominent nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2160.jpg" -"2161" "How would you describe the cytoplasm of the predominant cell population in this image?" "Clear and abundant" "Granular and amphophilic" "Scant and basophilic" "Dense and eosinophilic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2161.jpg" -"2162" "Based on the cellular morphology observed in the image, which type of cells are predominantly present?" "Hepatocytes" "Fibroblasts" "Chondrocytes" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2162.jpg" -"2163" "Based on the arrangement of the pink to red strands in the extracellular matrix, which areas suggest active tissue repair?" "Regions with haphazardly organized fibers" "Areas without any visible cellular structures" "Areas where fibers are parallel and orderly arranged" "Regions with predominantly blue cells without visible fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2163.jpg" -"2164" "Based on the staining pattern and cell morphology observed in the image, the expression of the protein detected through immunohistochemistry is:" "Inconsistent and variable across different cells" "Localized only in the nuclei of cells" "Present uniformly across the majority of the cells" "Absent in all carcinoma cells but present in surrounding tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2164.jpg" -"2165" "Which features indicate that these adipocytes are mature?" "Hyperchromatic nucleus" "Dense nucleus" "Multinucleation" "Peripheral nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2165.jpg" -"2166" "What does the tissue morphology transition within the image suggest?" "A smooth continuity between the fibrous stroma and the surrounding tissue with no clear demarcation suggests a benign growth pattern." "The presence of a clear demarcation line between the fibrous stroma and the adjacent less dense tissue is suggestive of a pathological process." "An abrupt transition from dense fibrous stroma to a less cellular area suggests non-malignant tissue organization." "A gradual transition from dense fibrous stroma to homogenous tissue indicates benign cellular adaptation." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2166.jpg" -"2167" "What cellular arrangement is predominantly seen in the main field of this image?" "Cells arranged in an acinar pattern" "Cells randomly scattered without a distinctive arrangement" "Cells organized in a palisading pattern" "Cells forming whorls or a swirling pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2167.jpg" -"2168" "Based on the morphology seen in the inset, what type of cell is prominently featured?" "Mast cell characterized by a round shape and cytoplasmic granules" "Lymphocyte with a large nucleus and scant cytoplasm" "Neutrophil with lobed nucleus and neutral staining granules" "Eosinophil due to the presence of bilobed nucleus and crystalline granules" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2168.jpg" -"2169" "What can be inferred about the elongated, spindle-shaped cells based on the nuclei's appearance?" "The nuclei have multiple lobes indicative of a high grade malignancy" "The nuclei are relatively uniform, suggesting an organized and possibly benign growth pattern" "The densely stained nuclei suggest a benign process" "The nuclei demonstrate marked pleomorphism and hyperchromaticity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2169.jpg" -"2170" "What does the morphology of the glomerulus in this image primarily suggest?" "Crescentic glomerulonephritis with proliferation of parietal epithelial cells and extracellular matrix" "Diabetic glomerulosclerosis with nodular glomerulosclerosis" "Membranous nephropathy with uniform thickening of the glomerular basement membrane" "Minimal change disease with effacement of foot processes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2170.jpg" -"2171" "Based on the pathology seen in this glomerulus, what is a likely clinical finding that may be associated with this condition?" "Nephrotic syndrome" "Asymptomatic hematuria" "Heavy proteinuria" "Rapidly progressive glomerulonephritis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2171.jpg" -"2172" "What is the predominant orientation of the nuclei within the columnar epithelial cells lining the tubular structures?" "Randomly scattered throughout the cytoplasm" "Basally oriented within the cells" "Central within the cells" "Apically oriented within the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2172.jpg" -"2173" "What type of staining technique was most likely used in this microscopic image based on the coloration present?" "Wright's stain" "Giemsa stain" "Hematoxylin and eosin (H&E)" "Periodic acid-Schiff (PAS)" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2173.jpg" -"2174" "Based on the visible morphological features, what type of tissue is likely represented in this microscopic image?" "Connective tissue" "Smooth muscle tissue" "Cardiac muscle tissue" "Skeletal muscle tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2174.jpg" -"2175" "What is the likely composition of the deep purple granular deposits scattered throughout the tissue in this image?" "Melanin" "Lipofuscin" "Glycogen" "Hemossiderin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2175.jpg" -"2176" "Based on the observed morphology, which statement best describes the integrity of the pulmonary architecture?" "The alveolar structure is markedly distorted" "The alveolar architecture is mildly disrupted" "There is no visible alteration to the alveolar architecture" "There is a well-preserved alveolar structure" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2176.jpg" -"2177" "What type of inflammatory cells can be identified in the lamina propria based on their cytoplasmic characteristics?" "Lymphocytes with dense, dark nuclei" "Macrophages with foamy cytoplasm" "Neutrophils with multi-lobed nuclei" "Eosinophils with pink to reddish cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2177.jpg" -"2178" "In the context of an immune response, what does this image suggest with the visible infiltrates?" "Absence of inflammatory cells in the dermis" "A dense inflammatory infiltrate in the deep dermis" "A heavy infiltrate of neutrophils throughout the epidermis" "A mild superficial perivascular lymphocytic infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2178.jpg" -"2179" "What cellular characteristic is NOT visible in the columnar epithelial cells on the left side of the image?" "Brush border" "Tube-like glandular structures" "Basally located nuclei" "Cilia on the apical surface" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2179.jpg" -"2180" "Based on the microscopic characteristics visible in this image, what is the nature of the matrix in which the spindle-shaped cells are embedded?" "Chondroid" "Collagenous" "Osteoid" "Myxoid" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2180.jpg" -"2181" "What is the pattern of the vascular structures present in the tissue section visible in this image?" "Glomeruloid microvascular proliferation" "Kaposi sarcoma-like pattern" "Cavernous hemangioma pattern" "Staghorn-like appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2181.jpg" -"2182" "Considering the overall architecture and cellularity of the tissue in this image, what is the most likely diagnosis?" "Dermatofibrosarcoma Protuberans" "Desmoid-Type Fibromatosis" "Malignant Peripheral Nerve Sheath Tumor" "Solitary Fibrous Tumor" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2182.jpg" -"2183" "Considering the larger red-stained structures within some of the blood-filled spaces, what is their most likely composition?" "Necrotic tissue" "Thrombotic masses" "Aggregates of erythrocytes" "Clusters of malignant cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2183.jpg" -"2184" "What specialized feature can be identified on the apical surfaces of the epithelial cells lining the cyst?" "Cilia" "Microvilli" "Goblet cells" "Keratinization" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2184.jpg" -"2185" "What does the variation in cell size and shape observed in this image suggest about the population of cells?" "The cells are of a different tissue type entirely" "The cells are likely homogenous, coming from only one cell line" "The cells represent a mixture of activated and resting cells" "The cells are in different stages of the cell cycle" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2185.jpg" -"2186" "Based on the staining characteristics and morphology, what is the most likely identity of the filamentous structures in the image?" "Fungal hyphae" "Collagen fibers" "Nerve fibers" "Acid-fast bacteria" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2186.jpg" -"2187" "What feature in this image suggests that the white matter appears less affected in comparison to the granular layer?" "Presence of pyknotic cells in high density" "Loss of cellular structure" "Uniform staining without evidence of vacuolation" "Easier visibility of axonal processes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2187.jpg" -"2188" "What feature does the star symbol (*) in the image primarily highlight?" "Dystrophic calcification" "Adipose tissue" "Myxoid degeneration" "Blood vessel" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2188.jpg" -"2189" "What does the arrow (→) in the image indicate?" "Adipose tissue" "Neoplastic cells" "Fibrotic tissue" "Bony tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2189.jpg" -"2190" "What is the appearance of the cytoplasm of the columnar epithelial cells?" "Basophilic" "Amphophilic" "Clear" "Eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2190.jpg" -"2191" "Where is the refractile brown material, as indicated by the arrows, primarily located within the tissue?" "Within the connective tissue stroma" "Within the luminal space" "Within the columnar epithelial cells" "Within the gland-like structures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2191.jpg" -"2192" "What does the intensity of the brown cytoplasmic staining in the cells mostly suggest about the expression of the ASS1 protein?" "Uniform low-level expression across all cells" "Heterogeneous expression of ASS1 with both positive and negative staining cells" "No expression of ASS1 in any cells" "Homogeneous high-level expression throughout the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2192.jpg" -"2193" "Based on the shape and organization of the cells within the extracellular matrix, which type of connective tissue does this image most likely represent?" "Dense regular connective tissue" "Cartilage" "Adipose tissue" "Dense irregular connective tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2193.jpg" -"2194" "Based on the microscopic appearance, what type of connective tissue is present in the stroma surrounding the cell clusters?" "Elastic connective tissue" "Loose areolar connective tissue" "Dense irregular connective tissue" "Adipose tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2194.jpg" -"2195" "What is the predominant cellular morphology visible in this colon tissue sample?" "Monomorphic cells with clear cytoplasm" "Uniform cells with small, regular nuclei" "Small cells with high nucleus-to-cytoplasm ratio" "Pleomorphic cells with hyperchromatic nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2195.jpg" -"2196" "Based on the morphological features observed in the hepatocytes, what is the most likely histopathological change occurring?" "Ground glass hepatocyte appearance" "Ballooning degeneration" "Macrovesicular steatosis" "Mallory bodies" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2196.jpg" -"2197" "Considering the overall appearance of the liver tissue, which feature is NOT evident at this magnification?" "Disrupted architecture due to fibrosis" "Inflammatory cell infiltrate" "Sinusoidal congestion" "Cholestasis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2197.jpg" -"2198" "Based on the morphology of the ovoid structures within the cyst-like space, what is the likely internal structure of these entities?" "Viral inclusion bodies" "Necrotic cell debris" "Bacterial colonies" "Parasitic mites" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2198.jpg" -"2199" "What is the appearance of the extracellular matrix surrounding the tumor cells?" "Basophilic with heavy mucopolysaccharide concentration" "Myxoid with scattered reticular fibers" "Pink-stained, abundant collagen" "Loose connective tissue with adipocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2199.jpg" -"2200" "Based on the cellular morphology, how would you describe the level of nuclear pleomorphism in this tissue section?" "Moderate" "Mild" "Absent" "Severe" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2200.jpg" -"2201" "Based on the staining characteristics observed in the image, which component is most likely to represent the peripheral brush border?" "The pinker outer rim of the structure" "The darkest purple-stained area" "The pale central part" "The area with spindle-shaped nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2201.jpg" -"2202" "What does the eosinophilic rimming around the central paler staining suggest regarding tissue composition?" "High density of cellular nuclei" "Accumulation of extracellular matrix components" "Presence of a high concentration of acidic proteins" "High lipid content within the cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2202.jpg" -"2203" "What is the predominant staining characteristic of the structure identified with the label 'vg'?" "It shows a dense eosinophilic staining." "It has primarily dark blue hematoxylin-stained nuclei." "It is characterized by a lack of distinguishable staining." "It exhibits lighter eosinophilic staining in the cytoplasm." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2203.jpg" -"2204" "Based on the cell staining observed, which cytokeratin is likely present in the epithelial cells indicated?" "Cytokeratin 19" "Cytokeratin 5" "Cytokeratin 20" "Cytokeratin 14" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2204.jpg" -"2205" "Based on the arrangement of the glandular structures seen in this H&E stained tissue section, which statement best describes the morphology?" "The glandular structures are uniformly shaped without any evidence of cellular atypia" "The glandular structures show minimal atypia with well-defined luminal spaces" "The glandular structures are arranged in a disorganized manner with variable cytoplasmic characteristics" "The glandular structures exhibit well-differentiated duct formation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2205.jpg" -"2206" "In the context of the surrounding stroma, what feature of the spindle cells can be observed in this tissue section?" "The spindle cells are uniformly distributed with minimal nuclear atypia" "The spindle cells contain large, vesicular nuclei with prominent nucleoli and abundant cytoplasm" "The spindle cells have small, hyperchromatic nuclei with scant cytoplasm" "The spindle cells display elongated nuclei and are densely packed with eosinophilic cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2206.jpg" -"2207" "What cellular component predominantly characterizes the pink-staining matrix element of the tissue?" "Hyaline cartilage" "Elastic fibers" "Striated muscle fibers" "Collagen fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2207.jpg" -"2208" "Based on the nuclear staining pattern, what is the likely level of nuclear protein expression in these cells?" "Low nuclear protein expression" "No nuclear protein expression" "Moderate nuclear protein expression" "High nuclear protein expression" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2208.jpg" -"2209" "Judging by the image, how would you describe the nucleus-to-cytoplasm ratio of most cells?" "High nucleus-to-cytoplasm ratio" "Low nucleus-to-cytoplasm ratio" "Moderate nucleus-to-cytoplasm ratio" "Inconclusive based on image" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2209.jpg" -"2210" "What characteristic feature can be identified within the cells adjacent to the regions exhibiting the dark brown staining?" "Elongated nuclei" "Hyperchromasia" "Significant pleomorphism" "Multinucleation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2210.jpg" -"2211" "What is the pattern of distribution of the dark brown staining observed in the tissue?" "Staining marks the extracellular matrix excluding cell locations" "Staining is localized within the cell nuclei" "Staining is diffuse throughout the tissue without a clear pattern" "Staining is primarily localized around blood vessel structures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2211.jpg" -"2212" "Considering the morphology of the nuclei lining some of the structures and their arrangement, what is the most likely identity of these structures?" "Blood vessels" "Glandular acini" "Nerve bundles" "Skeletal muscle fibers" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2212.jpg" -"2213" "Based on the morphological characteristics visible in the image, which best describes the appearance of the bony structures, or trabeculae?" "The trabeculae appear reduced and thinned out." "The trabeculae are uniformly hypertrophied." "The trabeculae display a regular, uniform density." "The trabeculae exhibit increased density and irregularity." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2213.jpg" -"2214" "What is the morphology of the eosinophilic structure in the center of the image?" "Fibrous with distinct layers" "Granular with multiple inclusions" "Cellular with clear cytoplasm" "Homogenous and amorphous" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2214.jpg" -"2215" "What is the most likely identity of the darkly stained cells infiltrating the muscle tissue?" "Lymphocytes" "Eosinophils" "Macrophages" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2215.jpg" -"2216" "Based on the immunohistochemical staining pattern, what is the most likely type of cells the red arrows are pointing to?" "Adipocytes" "Macrophages" "Endothelial cells" "Fibroblasts" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2216.jpg" -"2217" "Considering the clustering pattern of the cells highlighted by the red arrows, what is the most likely physiological or pathological process taking place?" "Neoplastic proliferation" "Inflammatory response" "Normal tissue homeostasis" "Fibrotic scarring" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2217.jpg" -"2218" "What type of cellular response is most prominently displayed around the central structure?" "Chronic inflammatory response" "Acute inflammatory response" "Neoplastic proliferation" "Granulomatous inflammation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2218.jpg" -"2219" "Which of the following best describes the cellularity of the tissue surrounding the cells indicated by the arrows?" "Increased cellularity with high nuclear to cytoplasmic ratios" "Decreased cellularity with large amounts of extracellular matrix" "Regular spacing with consistent cellular architecture" "Homogeneous cell populations with low nuclear pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2219.jpg" -"2220" "What type of staining technique has most likely been used in this microscopic image based on the appearance of the background matrix and the stained structures?" "Periodic acid–Schiff (PAS) stain" "Hematoxylin and eosin (H&E) stain" "Modified Fite's stain" "Giemsa stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2220.jpg" -"2221" "The cell types with darkly stained nuclei densely packed together in this image are indicative of what type of reaction?" "Acute inflammatory response" "Necrotic tissue reaction" "Hyperplastic tissue growth" "Chronic inflammatory response" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2221.jpg" -"2222" "Based on the morphological features observed, which tissue is this section most likely taken from?" "Renal cortex" "Hepatic tissue" "Scleral tissue of the eye" "Gastrointestinal tract mucosa" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2222.jpg" -"2223" "Based on the morphology observed in this Gomori Methenamine-Silver stained section, which type of fungal organism is most likely represented by the larger black structures indicated by the arrows?" "Aspergillus species" "Cryptococcus species" "Candida species" "Histoplasma species" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2223.jpg" -"2224" "What is the predominant staining characteristic of the nuclei in the epithelial lobules?" "Uniformly light-staining nuclei throughout the lobules" "Pale nuclei towards the center and dark nuclei peripherally" "No discernible nuclei, indicating poor staining" "Uniformly dark-staining nuclei throughout the lobules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2224.jpg" -"2225" "Based on the image, what is the nature of the granuloma observed?" "Sarcoidal granuloma with asteroid bodies" "Caseating granuloma with central necrosis" "Noncaseating granuloma without central necrosis" "Suppurative granuloma with neutrophilic infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2225.jpg" -"2226" "Which feature in this image is consistent with an active immune response within the neoplastic tissue?" "The presence of cells with large nuclei and abundant eosinophilic cytoplasm" "The presence of cells with small hyperchromatic nuclei" "The evidence of extensive extracellular matrix between neoplastic cells" "The clear boundaries and well-organized structure of the tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2226.jpg" -"2227" "How can spongiosis be identified in the provided microscopic image?" "Widened spaces between cells in the lower layers of the epidermis" "Necrosis of the basal cell layer" "Clumping of keratinocytes" "Widened spaces between cells in the upper layers of the epidermis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2227.jpg" -"2228" "Based on the nuclear characteristics observed in the cells, which of the following best describes the nuclear morphology?" "Multilobed and hypersegmented nuclei" "Small, dense nuclei with minimal cytoplasm" "Large, round nuclei with a cartwheel appearance" "Irregular, hyperchromatic nuclei with prominent nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2228.jpg" -"2229" "What is the predominant feature of the intervillous spaces in this placental tissue?" "Abundance of villous capillaries" "Accumulation of eosinophilic material" "Scarcity of syncytial knots" "Presence of chorionic villi" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2229.jpg" -"2230" "In this bone marrow aspirate smear, which feature best identifies the early erythroid progenitors?" "Cells with pinkish cytoplasm and no apparent nucleus" "Pale pink discs with a lighter center" "Cells with high nucleus to cytoplasm ratio and densely stained chromatin" "Cells with multilobed nuclei and granular cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2230.jpg" -"2231" "What morphological feature represents reticulocytes in this Wright-Giemsa stained bone marrow aspirate smear?" "Small cells with clumped nuclear chromatin" "Cells lacking a nucleus with bluish cytoplasm" "Large cells with prominent nucleoli" "Small, densely nucleated cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2231.jpg" -"2232" "Which type of cell is indicated by the presence of pale pink discs with a lighter center in the cytoplasm in this image?" "Lymphocytes" "Eosinophils" "Myeloblasts" "Mature red blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2232.jpg" -"2233" "What feature of the secretory mechanism is suggested by the apical cytoplasmic features of the glandular cells in the image?" "Eccrine secretion" "Merocrine secretion" "Holocrine secretion" "Apocrine secretion" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2233.jpg" -"2234" "How would you characterize the nucleus distribution within the glandular cells based on the image?" "Hyperchromatic and clustered nuclei" "Anaplastic nuclei" "Uniform nuclei with prominent nucleoli" "Vesicular nuclei with multiple nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2234.jpg" -"2235" "How would you describe the condition of the bone marrow space based on the cellular composition?" "Hypercellular with a predominance of immature precursor cells" "Hypocellular with a prevalence of adipose tissue" "Hypocellular with a predominance of mature leukocytes" "Hypercellular with extensive particle or clot formation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2235.jpg" -"2236" "What histological feature is indicated by the blue asterisk in the image?" "Normal neuronal cell bodies" "Dense fibrillar structures" "Normal neuropil" "Perivascular cuff" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2236.jpg" -"2237" "Within the section marked by the red asterisks, what is the predominant histopathological finding?" "Gliosis" "Intracellular edema" "Perivascular cuff" "Ischemic neuronal damage" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2237.jpg" -"2238" "How do the cell borders appear in this tissue section?" "Indistinct and difficult to discern" "Prominently highlighted and clear" "Uniformly spaced and regular" "Distinct and well-defined" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2238.jpg" -"2239" "Considering the staining characteristics, what can be inferred about the type of stain used on this microscopic slide?" "Papanicolaou (Pap) stain" "Hematoxylin and Eosin (H&E) stain" "Periodic acid-Schiff (PAS) stain" "May-Grünwald Giemsa (MGG) stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2239.jpg" -"2240" "Based on the appearance of the glomerular capillaries, what characteristic best describes their cellular distribution?" "Widely spaced cells with clear lumens" "Hypercellularity with overlapping nuclei" "Neatly arranged endothelial cells with regular capillary loops" "Scattered cellularity with minimal overlap of nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2240.jpg" -"2241" "In this image of the glomerulus, what can be inferred about the mesangial areas?" "Mesangial areas show no significant changes" "Mesangial areas are fibrotic with hyaline deposits" "Mesangial areas show expanded matrix and increased cellularity" "Mesangial areas are reduced and sclerosed" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2241.jpg" -"2242" "Based on the staining characteristics, which cytoplasmic feature can be assessed with high confidence from this image?" "Abundant granular eosinophilic cytoplasm" "Abundant pale cytoplasm with sparse granules" "Cytoplasm filled with melanin pigment" "Cytoplasm containing multiple rod-shaped bacteria" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2242.jpg" -"2243" "Based on the microscopic appearance, what type of cells predominantly occupy the field in this image?" "Histiocytes with ample cytoplasm" "Lymphocytes with a small cytoplasm to nucleus ratio" "Fibroblasts with scant cytoplasm" "Neutrophils with multi-lobed nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2243.jpg" -"2244" "What is the predominant cell type found at the tip of the arrow in the epithelial layer as indicated by the high nuclear-to-cytoplasmic ratios?" "Neutrophils" "Lymphocytes" "Epithelial cells" "Erythrocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2244.jpg" -"2245" "Based on the cellular morphology, where is this tissue section likely to have been derived from?" "Gastrointestinal tract" "Hepatic lobule" "Skin epidermis" "Pulmonary alveoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2245.jpg" -"2246" "What does the brown cytoplasmic staining pattern in select cells within the tubular structures most likely represent?" "Hematoxylin counterstaining" "Immunohistochemical labeling for a specific marker" "Presence of lipid accumulation" "Necrosis of the tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2246.jpg" -"2247" "Based on the morphological features observed in the image, which statement best describes the nuclei of the epithelial cells lining the glands?" "The nuclei display anisokaryosis with high mitotic activity." "The nuclei are basophilic and appear intact." "The nuclei are hyperchromatic with prominent nucleoli." "The nuclei are small with dense chromatin and irregular shapes." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2247.jpg" -"2248" "How would you describe the nuclear-to-cytoplasmic ratio in the cells visible in the image?" "Multi-nucleated cells with a high nuclear-to-cytoplasmic ratio" "Large nuclei compared to scanty cytoplasm" "High nuclear-to-cytoplasmic ratio" "Relatively small nuclei in relation to the ample cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2248.jpg" -"2249" "Observing the liver tissue section, which type of infiltrating structures can be identified and where?" "Bacterial colonies within the portal triads." "Fungal hyphae infiltrating the hepatic artery." "Fungal hyphae within the blood vessels." "Viral inclusions within the hepatocytes." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2249.jpg" -"2250" "In which layer of the dermal tissue is the target antigen predominantly expressed?" "In the dense connective tissue stroma" "Across both the epidermal and dermal layers uniformly" "In the dermal lymphoid aggregates" "In the overlying epidermis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2250.jpg" -"2251" "What is the morphology of the cells expressing the target antigen in the dermis?" "Cuboidal with clear intercellular spaces" "Round to ovoid and densely packed" "Spindle-shaped and loosely arranged" "Flattened with extensive matrix deposition" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2251.jpg" -"2252" "What type of cells can be identified intermixed with the columnar epithelial cells lining the crypts?" "Goblet cells" "Paneth cells" "Plasma cells" "Squamous epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2252.jpg" -"2253" "Based on the appearance of cells in the lamina propria, what is a potential finding?" "Neutrophilic infiltration" "Lymphoid aggregates" "Fibroblastic proliferation" "Pigmented macrophages" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2253.jpg" -"2254" "Based on the nuclear staining pattern, what is the predominant phase of the cell cycle in the cells indicated by the red arrow?" "Mitotic phase" "G1 phase" "G0 phase" "S phase" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2254.jpg" -"2255" "What can be inferred about the cells surrounding the intraluminal spaces (circular voids) within the tissue?" "They indicate a high degree of angiogenesis" "They are predominantly in the G0 phase" "They are densely packed myofibroblasts" "They are showing signs of necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2255.jpg" -"2256" "Considering the heterogeneity of cell size and shape in the cluster indicated by the red arrow, what tissue process might be occurring?" "Tissue remodeling" "Neoplastic transformation" "Adipose tissue deposition" "Inflammatory response" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2256.jpg" -"2257" "Considering the pattern of staining observed, which of the following is a likely histopathological feature represented in this image?" "Acute edema" "Neutrophilic infiltration" "Lymphoid follicle formation" "Granulomatous inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2257.jpg" -"2258" "Based on the immunohistochemical pattern in this image, what could be a potential differential diagnosis?" "Pulmonary adenocarcinoma" "Pulmonary embolism" "Bronchial asthma" "Lymphocytic interstitial pneumonia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2258.jpg" -"2259" "What is the dominant morphology of the epithelial cells lining the tissue structures shown in the image?" "Varied shapes with small, hyperchromatic nuclei" "Varied shapes with large, vesicular nuclei" "Uniform with large, hyperchromatic nuclei" "Uniform with small, round nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2259.jpg" -"2260" "Analyzing the structural organization of the tissue, what can be inferred about the normal cell maturation and polarity?" "Cells are mature, but exhibit loss of normal polarity" "Cells show loss of normal maturation and polarity" "Cells are immature and show normal polarity" "Cells demonstrate normal maturation with proper polarity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2260.jpg" -"2261" "Based on the morphology shown, which element is appearing relatively preserved?" "The tubular elements" "The glomerular basement membrane" "The endothelial cell layer" "The mesangial matrix" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2261.jpg" -"2262" "The areas consisting of small, round to oval cells with darker nuclei likely indicate:" "Formation of new adipose tissue" "A hyperplastic response of the epithelial cells" "Increased fibroblast activity leading to fibrosis" "Perivascular lymphocytic infiltration" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2262.jpg" -"2263" "What characteristic best describes the nucleus of the cell indicated by the arrow in the image?" "Multilobated 'popcorn-like' appearance" "Hyperchromatic and round" "Large with a prominent nucleolus" "Small and pyknotic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2263.jpg" -"2264" "Observing the chromatin pattern of the cell indicated by the arrow, which best describes its appearance?" "Vesicular with clear nucleoli" "Vesicular with areas of less dense staining" "Homogeneously dense" "Coarsely clumped" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2264.jpg" -"2265" "Based on the image, which feature suggests there might be mild pulmonary congestion present?" "Presence of pigmented deposits" "Branching structures indicative of airways" "Increased cellularity in areas of lung parenchyma" "Thickened alveolar septae" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2265.jpg" -"2266" "Based on the cellular morphology observed in the image, what is the likely nuclear characteristic of the cells present?" "Vesicular nuclei with prominent nucleoli" "Multinucleation with smudgy chromatin" "Hyperchromatic nuclei with high N:C ratio" "Uniform nuclei with salt and pepper chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2266.jpg" -"2267" "What can be inferred about the extracellular matrix in this tissue section based on the staining properties?" "It contains a high amount of collagen fibers due to red staining" "It is predominantly composed of lipid deposits due to clear vacuoles" "It appears homogeneously eosinophilic with pink staining" "It consists of densely packed cells with little intercellular substance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2267.jpg" -"2268" "Identify the feature that is least represented within the tissue section based on the image provided." "Homogeneous eosinophilic intercellular matrix" "Cells with a high nucleus-to-cytoplasm ratio" "Cytoplasm that stains darker than the nuclei" "Necrotic areas indicated by sparse lighter regions" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2268.jpg" -"2269" "What is the predominant morphology of the cells seen in this bone marrow aspirate?" "Predominantly mature myeloid and erythroid cells with abundant cytoplasm" "Predominantly adipocytes interspersed with hematopoietic elements" "Abundant megakaryocytes with mature platelet shedding" "A homogenous population of cells with high nuclear-to-cytoplasmic ratios" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2269.jpg" -"2270" "Which statement best describes the cellular arrangement in this bone marrow aspirate?" "A homogeneous population with little variation in cell size and shape" "The presence of a variety of differentiating hematopoietic cells" "A sparsely populated marrow with abundant stromal tissue" "A varied population with numerous mature erythroid precursors" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2270.jpg" -"2271" "What type of cells can be seen surrounding the central cluster of epithelioid cells?" "Erythrocytes" "Fibroblasts" "Lymphocytes" "Plasma cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2271.jpg" -"2272" "Observing the immunohistochemical (IHC) staining pattern, what can be inferred about the distribution of the protein of interest within the cells?" "It is evenly distributed throughout the cell" "It is primarily cytoplasmic" "It is absent in both nucleus and cytoplasm" "It is primarily nuclear" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2272.jpg" -"2273" "Which feature in the image is characteristic of lymphatic structures that can be highlighted by a specific marker such as D2-40?" "The brownish staining in some areas" "The elongated cells with tapered ends forming the bundles" "The irregular clear space indicated by the arrow" "The cluster of cells with eosinophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2273.jpg" -"2274" "When examining the epithelial lining in this microscopic view, what can be inferred about the cellular morphology from the periphery of the fold towards the center?" "From the periphery inward, cells display increased cytoplasmic clearing and less dense packing." "From the periphery inward, cells maintain a consistent cuboidal morphology." "From the periphery inward, cells transition from columnar or cuboidal to a more squamous morphology." "From the periphery inward, cells transition from a squamous to a columnar morphology." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2274.jpg" -"2275" "Analyzing the microscopic tissue section, which type of nucleus is predominantly seen in the basal layer of cells?" "Uniform nuclei with consistent staining" "Enlarged nuclei with increased clearing" "Prominent nuclei with dense chromatin" "Small and hypochromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2275.jpg" -"2276" "What histopathological sign might be indicated by the endothelial cells' appearance within the arterial nervorum?" "Necrosis with loss of cellular structure" "Endothelial proliferation with multilayering" "Endothelial shrinkage and potential angulation" "Hyperplasia with increased cell density" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2276.jpg" -"2277" "Based on the image, what is the likely function of the epithelium shown?" "Protection against abrasion." "Propulsion of mucus and particles." "Absorption of nutrients." "Secretion of mucus." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2277.jpg" -"2278" "Analyzing the image, what does the pink amorphous substance beneath the epithelial layer likely indicate?" "Proliferation of smooth muscle cells." "Dense accumulation of collagen fibers." "Thickened basement membrane." "Accumulation of adipose tissue." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2278.jpg" -"2279" "Based on this image, what observation can be made about CK20 staining in these glandular structures?" "There is no CK20 staining in the glandular structures" "There is positive CK20 staining with brown coloration" "There is a heterogeneous pattern of CK20 staining" "CK20 staining is localized to the nuclei of the cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2279.jpg" -"2280" "Which cellular structures identified by the black arrows are indicative of granulomatous inflammation?" "Epithelioid cells" "Ciliated pseudostratified columnar epithelial cells" "Multinucleated giant cells" "Inflammatory cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2280.jpg" -"2281" "What is the staining characteristics of the rod-shaped structures in the image?" "They take up a blue stain and appear dark blue" "They are unstained and appear transparent" "They take up a green stain and appear green" "They take up a red stain and appear red" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2281.jpg" -"2282" "What is the predominant staining pattern observed in the majority of the cells within this microscopic field?" "Nuclear localization" "Cytoplasmic localization" "Extracellular matrix staining" "Membrane-associated localization" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2282.jpg" -"2283" "Considering the morphological features observed in the tissue, which cell type does the majority of the shape and staining pattern of the cells suggest?" "Cuboidal epithelial cells" "Columnar epithelial cells" "Round lymphocytes" "Spindle-shaped connective tissue cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2283.jpg" -"2284" "In Area 1 of the image, which feature is NOT observed due to confluent hepatocyte necrosis?" "Preservation of normal cellular architecture" "Loss of nuclear staining" "Presence of intact hepatocytes" "Eosinophilic staining of cell debris" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2284.jpg" -"2285" "What type of immune cells can be found in Area 3 of the image?" "Eosinophilic granulocytes with bilobed nuclei" "Neutrophils with multilobed nuclei" "Lymphocytes with large, spherical nuclei" "Macrophages with kidney-shaped nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2285.jpg" -"2286" "Based on the cellular morphology, what is the nuclear-to-cytoplasmic ratio observed in the majority of epithelial cells displayed in the image?" "Low nuclear-to-cytoplasmic ratio" "High nuclear-to-cytoplasmic ratio" "Indeterminable nuclear-to-cytoplasmic ratio" "Equal nuclear-to-cytoplasmic ratio" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2286.jpg" -"2287" "Looking at the cellular characteristics in the image, what type of chromatin pattern do nuclei of the epithelial cells mostly show?" "Homogeneous chromatin distribution" "Absence of visible chromatin" "Fine and evenly dispersed chromatin" "Coarse and clumped chromatin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2287.jpg" -"2288" "What observation can be made regarding the eosinophils present in this peripheral blood smear?" "They display typical mature forms with heavy granulation" "They show a left shift indicating immature forms" "Their nuclei exhibit regular segmentation with typical granule appearance" "They exhibit hypogranulation with excessive granule density" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2288.jpg" -"2289" "Considering the cell boundaries and cellular cohesion in the image, how would you classify the level of differentiation in these cells?" "Undifferentiated" "Well-differentiated" "Poorly differentiated" "Moderately differentiated" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2289.jpg" -"2290" "What feature distinguishes the cells indicated by the arrows from other hematopoietic cells in this image?" "The presence of cytoplasmic granules" "The presence of large and lobulated nuclei" "The presence of dense chromatin" "The presence of a basophilic cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2290.jpg" -"2291" "Which other hematopoietic cell lineages can likely be observed in the background of this image, as suggested by the cell morphology?" "Lymphoid and erythroid lineages" "Myeloid and lymphoid lineages" "Erythroid and myeloid lineages" "Lymphoid and megakaryocytic lineages" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2291.jpg" -"2292" "Based on the longitudinal section of striated muscle tissue presented, what is the predominant eosin staining pattern of the cytoplasm?" "Dark pink with numerous dark inclusions" "Homogeneous pink with occasional streaks" "Light pink with consistent cross striations" "Pale pink with pronounced longitudinal striations" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2292.jpg" -"2293" "Based on the presence and morphology of inflammatory cells in the portal tract, which cell type appears to be the most prominent?" "Eosinophils with bi-lobed nuclei and sparse granular cytoplasm" "Lymphocytes with small, dark nuclei and scant cytoplasm" "Neutrophils with uniform, round nuclei and abundant cytoplasm" "Macrophages with large, vesicular nuclei and foamy cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2293.jpg" -"2294" "Based on the staining patterns observed in the micrograph, which area is indicative of the strongest expression of the target protein?" "The area labeled as 'T'" "The area labeled as 'IGCN'" "The area labeled as 'S'" "The area with no specific labeling" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2294.jpg" -"2295" "Examine the morphological features in the image. Which labeled structure displays a high nucleocytoplasmic ratio and closely packed cells without a lot of intercellular space?" "The area labeled as 'T'" "The area labeled as 'S'" "The inset at the bottom right corner" "The area labeled as 'IGCN'" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2295.jpg" -"2296" "What histological feature distinguished intratubular germ cell neoplasia (IGCN) from benign tubular structures in this immunohistochemical stain?" "IGCN has less distinct cellular borders than benign tubules" "IGCN shows more intense staining than benign tubules" "IGCN exhibits a lower nucleocytoplasmic ratio than benign tubules" "IGCN has a more irregular luminal space than benign tubules" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2296.jpg" -"2297" "Based on the histological appearance of the nuclei, what can be inferred about the cells in the hypercellular region?" "The nuclei are uniform and suggest benign character." "The nuclei exhibit a high nuclear-to-cytoplasmic ratio." "The nuclei appear hyperchromatic with prominent nucleoli." "The nuclei show significant pleomorphism." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2297.jpg" -"2298" "How does the extracellular matrix in the hypocellular region appear when compared to the hypercellular region?" "There is no visible difference in the extracellular matrix between regions." "There is an increase in extracellular matrix that is densely stained." "There is a decrease in extracellular matrix with less defined staining." "The extracellular matrix has more ground substance with a lighter stain." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2298.jpg" -"2299" "What is the most likely staining method used in this tissue sample based on the coloration seen in the image?" "Periodic acid-Schiff (PAS) staining" "Hematoxylin and Eosin (H&E) staining" "Masson's Trichrome staining" "Papanicolaou (Pap) staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2299.jpg" -"2300" "Based on the microscopic image, which of the following is a distinguishing feature of the cellular structure indicated by the arrow?" "Presence of cytoplasmic inclusions" "Multi-nucleation" "Single ovoid nucleus" "Clear halo surrounding the nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2300.jpg" -"2301" "The histological section reveals regions with paler staining. What is the most likely pathological process occurring in those regions?" "Atrophy" "Edema" "Inflammation" "Fibrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2301.jpg" -"2302" "What is the predominant cell type visible in the area with high cellularity on the right side of the image?" "Neutrophils" "Fibroblasts" "Lymphocytes" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2302.jpg" -"2303" "Based on the appearance of the extracellular matrix, which of the following best describes the area on the left side of the image?" "Area of necrosis with cellular debris" "Hyaline cartilage with chondrocytes in lacunae" "Edematous area with fluid accumulation" "Collagen-rich area with dense fibrous tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2303.jpg" -"2304" "What feature does the area indicated by the left green arrow primarily demonstrate?" "Hyaline cartilage with chondrocytes in lacunae" "Dense and disorganized arrangement of collagen fibers" "Necrotic tissue with abundant cell debris" "Granulomatous inflammation with multinucleated giant cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2304.jpg" -"2305" "What does the tissue morphology in the area indicated by the right green arrow suggest?" "Squamous epithelium with keratinized layers" "Adipose tissue with vacuolated cells" "Smooth muscle tissue with spindle-shaped cells" "Lymphocytic infiltrate with densely packed cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2305.jpg" -"2306" "What feature of the nuclei in the epithelial cells indicates a high nuclear-to-cytoplasmic ratio?" "Large, pale staining nuclei with ample cytoplasm" "Elongated, hyperchromatic nuclei with crowding and overlapping" "Uniform nuclei with abundant surrounding cytoplasm" "Small, darkly stained nuclei with scant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2306.jpg" -"2307" "What pattern of cellular organization does the tissue display?" "Papillary fronds with a central fibrovascular core" "Cystic spaces lined by flat, benign epithelium" "Uniform glandular structures with cohesive organization" "Small, round acinar formations disconnected from each other" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2307.jpg" -"2308" "What can be inferred regarding the presence of inflammation in the tissue section?" "The predominant cell population is that of inflammatory cells." "There is a heavy infiltration of inflammatory cells." "The inflammatory reaction is uniform across the tissue section." "There is little to no evidence of significant inflammation." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2308.jpg" -"2309" "What does the scant cytoplasm surrounding the nuclei suggest about the population of cells in the image?" "High rate of cell division" "Senescence" "Mature leukocyte differentiation" "Ductal differentiation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2309.jpg" -"2310" "Based on the immunohistochemical staining pattern observed in the image, what can be inferred about the expression of the targeted markers in the cluster of cells?" "The cells express the targeted markers heterogeneously, with some cells staining more intensely than others." "The cells express the targeted markers uniformly, with consistent staining throughout the cluster." "The targeted markers are only expressed in the nuclei of the cells." "The cells do not express the targeted markers at all." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2310.jpg" -"2311" "Considering the cellular morphology seen in the red-stained cells, which of the following morphological characteristics is not observed?" "A cohesive nature suggestive of epithelial-derived tissue." "Cells that adhere together in a cohesive manner." "Pleomorphic nuclei with varying sizes and shapes." "Cells with uniform nuclei of similar size and shape." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2311.jpg" -"2312" "Based on the presence of brownish coloration in the tissue sample, which immunohistochemical protein could this staining pattern be indicative of?" "GFAP" "CD20" "Cytokeratin" "Vimentin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2312.jpg" -"2313" "Assessing the alveolar architecture, which statement best describes the observed pathological changes?" "The alveolar architecture is completely normal with clear air spaces and thin septa" "The alveolar architecture is well preserved with minimal septal thickening" "There is mild disruption of the alveolar architecture with slight septal thickening" "There is pronounced disruption of the alveolar architecture with noticeable septal thickening" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2313.jpg" -"2314" "Based on the muscle fiber morphology observed, what is the most likely orientation of the section?" "Cross-sectional oblique" "Tangential section" "Purely cross section" "Longitudinal section" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2314.jpg" -"2315" "Considering the location of the nuclei, what type of muscle tissue is depicted in the image?" "Cardiac muscle" "No muscle tissue" "Smooth muscle" "Skeletal muscle" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2315.jpg" -"2316" "Upon examination of the glandular structures' epithelial cells, what feature can be observed regarding the orientation of the nuclei?" "The nuclei are basally oriented and appear darker" "The nuclei are located apically and exhibit polymorphism" "The nuclei are randomly distributed and hyperchromatic" "The nuclei are mostly peripheral and flattened" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2316.jpg" -"2317" "Based on the cellular morphology observed under the microscope, which of the following features is most consistently associated with the cells present in this tissue section?" "The cells have eccentrically placed nuclei and abundant perinuclear cytoplasm suggesting plasma cells" "The presence of multi-nucleation and bizarre nuclear shapes suggesting a neoplastic process" "The cells have hyperchromatic, irregular nuclei indicative of high-grade dysplasia" "Cells with scant cytoplasm and densely packed chromatin typical of lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2317.jpg" -"2318" "Based on the cellular morphology, which component is NOT evident within the tissue section?" "Spaces or 'clefts' within the tissue" "Multilobulated neutrophils indicative of acute inflammation" "Areas of adipose tissue" "Dense clusters of cells with hyperchromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2318.jpg" -"2319" "What can be inferred from the overall tissue organization observed in the image?" "A loss of normal tissue architecture and potential microabscess formation" "The tissue shows normal, healthy organization" "The presence of neoplastic cells forming a tumor mass" "Evidence of chronic inflammation with granuloma formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2319.jpg" -"2320" "When examining the nuclear features in this histological image, what is NOT consistent with a diagnosis of a neoplasm of low malignant potential?" "Enlarged nuclei" "Vesicular nuclei with open chromatin" "Uniform nuclear size" "Pleomorphism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2320.jpg" -"2321" "Are there any signs of necrosis within the cellular clusters visible in the microscope image?" "Yes, there is evidence of pink-staining amorphous debris" "Yes, there is evidence of large areas of dark staining karyorrhectic debris" "No, but the clusters show signs of hyalinization" "No, the clusters lack pink-staining amorphous debris" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2321.jpg" -"2322" "Identify the cytoplasmic structures observed in some of the cells within the image." "Mitochondria with a clear cristae structure" "Eosinophilic granules of varying sizes" "Lipid droplets scattered uniformly across the cytoplasm" "Large vacuoles indicative of cytoplasmic degeneration" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2322.jpg" -"2323" "Based on the staining characteristics in the image, what type of stain is likely to have been used?" "Hematoxylin and Eosin (H&E) stain" "Masson's trichrome stain" "Silver stain" "Periodic acid-Schiff (PAS) stain" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2323.jpg" -"2324" "What pattern of immunoreactivity is demonstrated by the cells?" "Membranous staining" "Cytoplasmic staining" "Nuclear staining" "No staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2324.jpg" -"2325" "How are the nuclei of the cells visualized in this immunohistochemically stained section?" "They are stained pink" "They are stained with a blue/purple hue" "They are unstained" "They are stained brown" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2325.jpg" -"2326" "What is the primary pathological finding in the area indicated by the blue arrow?" "Necrosis" "Cholestasis" "Steatosis" "Fibrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2326.jpg" -"2327" "What tissue component associated with mesenchymal origin is providing the pinkish coloration to the background stroma in this Hematoxylin and Eosin (H&E) stained image?" "Reticular fibers" "Myxoid matrix" "Fatty tissue" "Collagen fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2327.jpg" -"2328" "Based on the cellular architecture, which layer demonstrates epithelial hyperplasia?" "The areas of pale staining with loss of cellular borders" "The middle layer with densely populated cells" "The topmost layer with closely packed cells" "The bottommost layer adjacent to the white space" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2328.jpg" -"2329" "What are the smaller cells with high nuclear-to-cytoplasmic ratios and homogenous chromatin likely to be?" "Erythrocytes" "Myeloblasts" "Eosinophils" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2329.jpg" -"2330" "What is the characteristic morphology of the cells surrounding the blood vessels?" "Flat cells with elongated nuclei" "Large cells with abundant eosinophilic cytoplasm" "Small cells with hyperchromatic nuclei" "Large cells with abundant clear cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2330.jpg" -"2331" "In comparing panels (a) and (b), which histopathological characteristic appears more pronounced with the hematoxylin stain compared to the Papanicolaou stain?" "Cytoplasmic detail and staining intensity" "Cell-to-cell variability in the extracellular matrix staining" "Nuclear detail such as prominence of nucleoli" "The contrast between nuclei and the surrounding cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2331.jpg" -"2332" "Based on the microscopic features observed in the image, what is the predominant characteristic of the nuclei within these cells?" "Multinucleation" "Presence of prominent nucleoli in all cells" "High degree of pleomorphism" "Uniform size and shape" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2332.jpg" -"2333" "The brown-stained cells scattered throughout the tissue indicate:" "Positive immunohistochemical reaction marking specific antigens" "Deposition of melanin pigment in melanocytes" "Presence of hemosiderin-laden macrophages" "Accumulation of lipid within foam cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2333.jpg" -"2334" "What does the organization of the cellular architecture in the given tissue sample suggest?" "The tissue shows significant fibrotic changes disrupting cell arrangement." "There is a high degree of cellular pleomorphism." "There is a disorganized growth pattern typical of neoplastic processes." "The cells exhibit a monotonous appearance indicating a uniform cell population." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2334.jpg" -"2335" "Considering the cytoplasmic staining of the cells labeled with 'N', which statement is true?" "The cytoplasm stains darkly, indicating a high content of RNA" "The cytoplasm shows a granular blue staining, typical for basophilic cells" "The cytoplasm is unstained, suggesting a lack of cytoplasmic organelles" "The cytoplasm exhibits a light eosinophilic stain, characteristic for neurons" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2335.jpg" -"2336" "What does the surrounding pinkish tissue most likely represent in this neural tissue sample?" "Presence of collagenous connective tissue" "Area of fibrosis or scarring" "Area indicative of demyelination" "Presence of neuropil with neuronal processes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2336.jpg" -"2337" "What pattern is predominantly observed in the fibrous tissue within this histological image?" "Alveolar pattern" "Storiform pattern" "Reticular pattern" "Fascicular pattern" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2337.jpg" -"2338" "What does the overall tissue architecture, as observed in the image, suggest?" "Normal tissue organization" "Neoplastic proliferation" "Acute inflammatory process" "Chronic inflammatory process with significant fibrosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2338.jpg" -"2339" "In the connective tissue stroma, what feature best describes the darkly stained, round structures observed among the fibers?" "Inflammatory infiltrates" "Nuclei of fibroblasts" "Adipose cells" "Erythrocytes within a blood vessel" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2339.jpg" -"2340" "How would you describe the cytoplasm of the cells within the ganglion cluster?" "Sparse and basophilic" "Generous and eosinophilic" "Scant and clear" "Abundant and amphophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2340.jpg" -"2341" "Based on the nuclear morphology visible in the image, which description best characterizes the appearance of the nuclei?" "The nuclei are uniform in appearance with multiple distinct intranuclear dots." "The nuclei exhibit anisonucleosis with conspicuous nucleoli." "The nuclei display significant pleomorphism and frequent mitotic figures." "The nuclei are predominantly hyperchromatic with irregular shapes." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2341.jpg" -"2342" "Considering the specificity of the staining pattern in the image, which probable technique might have been used to achieve this result?" "In situ hybridization" "Ziehl-Neelsen acid-fast stain" "Hematoxylin and eosin (H&E) staining" "Periodic acid-Schiff (PAS) reaction" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2342.jpg" -"2343" "What can be inferred about the cells lining the lumen of the glandular structures based on the brown staining?" "Expression of a specific marker or protein" "Presence of lipid droplets" "Signs of calcification" "Indication of glycogen within cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2343.jpg" -"2344" "What histological feature is indicated by the arrows in the image?" "Goblet cells" "Villi" "Intestinal crypts" "Smooth muscle fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2344.jpg" -"2345" "What is the most likely morphological classification of the bacteria present in the micrograph?" "Spirochetes" "Coccobacilli" "Cocci" "Bacilli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2345.jpg" -"2346" "Analyzing the cellular features under the microscope, what can be inferred about the cellular morphology of the nucleated cells?" "The cells are predominantly monocytes" "The cells are predominantly lymphocytes" "The cells are predominantly erythrocytes" "The cells are predominantly neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2346.jpg" -"2347" "Regarding the glandular architecture observed in this image, which of the following best describes the cellular arrangement?" "Highly organized glandular architecture with abundant stromal support." "Uniform glandular cells with a single layer and well-defined lumens." "Glandular structures with irregularly shaped clusters and an absence of invasion." "Sheets of neoplastic cells without any glandular differentiation." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2347.jpg" -"2348" "Upon observing the image, what can be inferred about the tissue architecture?" "There is a mixture of densely packed cells with abundant extracellular matrix" "The tissue shows an organized layering with cellular uniformity" "The cells demonstrate uniformity in size and shape, indicating well-differentiated tissue" "There is a loss of normal tissue structure with cellular pleomorphism" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2348.jpg" -"2349" "Based on the cellular morphology observed in the image, what is the predominant cell shape within this tissue section?" "Cuboidal cells with round central nuclei" "Spindle-shaped cells with elongated nuclei" "Columnar cells with basal nuclei" "Spherical cells with prominent nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2349.jpg" -"2350" "In terms of cellular organization, which description best fits the arrangement seen in this image?" "Cells organized in tightly packed acini" "Disorganized, haphazard arrangement of cells" "Well-structured, linearly arranged cells" "Cells organized in well-delineated nests" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2350.jpg" -"2351" "In the image provided, what can be inferred about the ratio of intranuclear signals based on the labeled indicators?" "No intranuclear signals are present" "Dark intranuclear signals outnumber the red signals" "Red intranuclear signals outnumber the dark signals" "There is an equal ratio of dark to red intranuclear signals" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2351.jpg" -"2352" "What observation can be made about the cytoplasmic volume relative to the nuclei from the provided image?" "Balanced nuclear-to-cytoplasmic ratio" "Abundant cytoplasm surrounding the nuclei" "Moderate amount of cytoplasm present around the nuclei" "Scant cytoplasm around the nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2352.jpg" -"2353" "What is the predominant staining characteristic of the cytoplasm in the tissue cells observed in the image?" "Predominantly pale" "Heterogeneously stained" "Darkly basophilic" "Intensely eosinophilic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2353.jpg" -"2354" "How are the nuclei positioned within the cells of the gland-like structures?" "Apically located" "Basally located" "Randomly scattered" "Centrally located" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2354.jpg" -"2355" "What are the small red-stained structures observed on the surface of the tissue?" "Erythrocyte aggregates" "Muscle fibers" "Spirochetes" "Red blood cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2355.jpg" -"2356" "Based on the cellular morphology present in this image, what size are the majority of the spherules observed?" "80-100 microns in diameter" "20-40 microns in diameter" "40-60 microns in diameter" "60-80 microns in diameter" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2356.jpg" -"2357" "What is the characteristic pattern of the brown staining observed in the nuclei of the cells?" "Exclusively located at the nuclear periphery" "Homogeneous throughout the entire nuclei" "Present as punctate foci within the nuclei" "Heterogeneous with varying intensity across different nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2357.jpg" -"2358" "Based on the visible nuclear staining characteristics, what might you infer about the distribution of the antigen being targeted by the immunohistochemistry?" "It is uniformly present in all cells observed" "It is localized outside of the nuclei" "It exhibits a variation in expression levels between cells" "It is absent from the cells observed" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2358.jpg" -"2359" "Based on the distribution of the lymphoid cells in the microscopic image, what pattern does the infiltrate suggest?" "Diffuse infiltration of cells throughout the tissue" "Uniform distribution of lymphoid cells in a linear pattern" "Lymphoid cells localized to certain areas, possibly indicating an organized lymphoid structure" "Lymphoid cells concentrated at the periphery with a clear center" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2359.jpg" -"2360" "Considering the visible morphology of the cells in the image, what is the most characteristic feature of the cells observed?" "Cells exhibit large cytoplasmic area relative to the nuclei" "Multinucleated cells with clearly discernible cytoplasmic boundaries" "The cells are predominantly round with a small cytoplasmic rim" "Irregularly shaped nuclei with a high nucleus-to-cytoplasm ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2360.jpg" -"2361" "Which cells in the image predominantly exhibit darkly stained, round nuclei and are densely packed together?" "Adipocytes" "Fibroblasts" "Epithelial cells" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2361.jpg" -"2362" "Which of the following best describes the cell morphology visible in images A and B at the bottom (basal) layer?" "Spindle-shaped cells with cytoplasmic staining" "Columnar cells with intense nuclear staining" "Flattened and irregular cells with sparse nuclear staining" "Rounded cells with minimal intercellular spaces" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2362.jpg" -"2363" "Comparing the fluorescent signal in images C and D, what can be inferred about the vitamin D receptor protein concentration in the nuclei of the keratinocytes?" "The concentration is uniform in both images" "Image D shows a more intense fluorescence than image C" "There is no visible fluorescent signal in either image" "Image C exhibits a slightly more intense nuclear staining compared to image D" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2363.jpg" -"2364" "What feature best describes the appearance of the eosinophilic deposits indicated by the arrow in the provided image?" "Loose, fibrillar texture" "Homogenous, acellular and sharply demarcated" "Granular, fragmented aggregates" "Irregular, cellular infiltrate" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2364.jpg" -"2365" "Identify the description that best fits the population of mononuclear cells in this image." "Cells with high nucleus-to-cytoplasm ratios and irregular shape" "Cells with round, singular nuclei and a homogenous staining pattern" "Large cells with eosinophilic cytoplasm containing multiple nuclei" "Spindle-shaped cells with large, hyperchromatic nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2365.jpg" -"2366" "How would you describe the pleomorphism of the cells in this tissue section?" "Significant variation in size and shape" "Extreme cellular disarray with pronounced pleomorphism" "Moderate pleomorphism with identifiable cellular hierarchies" "Uniform in size and shape with no significant atypia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2366.jpg" -"2367" "What characteristic feature is indicated by the yellow arrows in the tissue sample?" "Lipid-laden macrophages" "Cardiomyocytes with disrupted morphology" "Mononuclear inflammatory cells" "Necrotic myocardial fibers" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2367.jpg" -"2368" "What does the presence of cells with multiple nuclei, as indicated by the green arrows, suggest about this cardiac tissue sample?" "Active cardiac muscle regeneration" "Healing myocardial infarction" "Presence of multinucleated giant cells indicating severe inflammation" "Hypertrophy of cardiac muscle cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2368.jpg" -"2369" "What predominant cell shape is observed in this tissue section?" "Predominantly cuboidal cells" "Predominantly columnar cells" "Predominantly squamous cells" "Predominantly spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2369.jpg" -"2370" "In this histological section with Hematoxylin and Eosin staining, what is the approximate depth of the intestinal crypts as annotated in micrometers?" "400-450 µm" "300-350 µm" "200-250 µm" "100-150 µm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2370.jpg" -"2371" "Based on the orientation and morphology of cells in the smooth muscle layers in this histological section, which muscle layer can be primarily identified?" "Muscularis externa" "Muscularis mucosae" "Circular muscle layer" "Longitudinal muscle layer" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2371.jpg" -"2372" "What does the presence of a basophilic area within the tissue suggest?" "Presence of lipid accumulation" "Presence of calcification" "Presence of hemorrhage" "Presence of glycogen stores" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2372.jpg" -"2373" "Based on the cytoplasmic characteristics of the cells observed in the image, which type of inclusion bodies can be suspected?" "Lewy bodies" "Michaelis-Gutmann bodies" "Russell bodies" "Mallory bodies" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2373.jpg" -"2374" "What alteration in tissue architecture is suggested by the intercellular spaces seen in the image?" "Hydropic change" "Tubular alteration" "Caseous necrosis" "Coagulative necrosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2374.jpg" -"2375" "Upon examining the nuclei, the staining suggests their chromatin structure is:" "Heterochromatic" "Euchromatic" "Pyknotic" "Karyorrhectic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2375.jpg" -"2376" "What type of epithelial cells predominantly line the tubular structures in the given image?" "Cuboidal epithelial cells" "Squamous epithelial cells" "Transitional epithelial cells" "Columnar epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2376.jpg" -"2377" "How do the epithelial cells appear after H&E staining in the image?" "Green with multiple nuclei" "Red with no visible nuclei" "Dark purple with centrally located nuclei" "Light pink with peripheral nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2377.jpg" -"2378" "Based on the morphology observed in the image, what type of infectious agent is most likely present within the tissue?" "Bacterial cocci clusters" "Viral inclusion bodies" "Protozoan parasites" "Fungal yeast and hyphae" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2378.jpg" -"2379" "What does the clear halo around some of the darkly stained structures in the tissue most likely represent?" "Spore formation in yeast cells" "Nuclei enveloped by cytoplasm" "Areas of cellular degeneration" "Artifacts of tissue processing" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2379.jpg" -"2380" "What does the presence of cells with darker-staining nuclei amidst the other hematopoietic cells in this micrograph likely indicate?" "Adipocytes" "Apoptotic cells" "Megakaryocytes" "Maturing myeloid cells or lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2380.jpg" -"2381" "Based on the cellular cytoplasm observed in this liver tissue section, what is the most appropriate description?" "There is extensive cytoplasmic vacuolization observed" "Cytoplasm of the hepatocytes shows multiple intracellular inclusions" "Hepatocytes display uniform eosinophilic cytoplasm" "The cytoplasm of the hepatocytes is predominantly basophilic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2381.jpg" -"2382" "What type of epithelium is identified in the upper portion of this histological image?" "Simple columnar epithelium" "Simple cuboidal epithelium" "Pseudostratified ciliated columnar epithelium" "Stratified squamous epithelium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2382.jpg" -"2383" "Assessing the cellular population scattered throughout the stroma adjacent to the capillaries, which type of cells can be presumed based on their morphological characteristics?" "Fibroblasts" "Neoplastic cells" "Inflammatory cells" "Endothelial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2383.jpg" -"2384" "Analyzing the structure of the glomeruli, which finding is consistent with the pathological changes seen in this image?" "Hypercellularity" "Hyalinosis" "Focal segmental glomerulosclerosis" "Capsular thickening" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2384.jpg" -"2385" "Considering the cellular architecture around the glomeruli, what is the most evident characteristic in the tubules and interstitial tissue?" "Preservation of normal architecture" "Interstitial fibrosis" "Atrophy" "Lymphocytic infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2385.jpg" -"2386" "Based on the tissue organization and cellular features noted within the image, which of the following conditions is the tissue most likely exhibiting?" "Biliary ductal proliferation" "Hepatic steatosis" "Hepatocellular carcinoma" "Normal liver parenchyma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2386.jpg" -"2387" "Examining the glomerulus indicated by the arrow, what histological changes can be observed?" "Crescent formation" "Uniform glomerular enlargement" "Segmental sclerosis" "Hypercellularity of glomerular capillaries" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2387.jpg" -"2388" "Focusing on the glomerulus not indicated by the arrow, what can be said about its morphology?" "It demonstrates normal glomerular structure" "It shows evidence of proliferative lesions" "It exhibits signs of membranous glomerulonephritis" "It depicts global sclerosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2388.jpg" -"2389" "What morphological feature is indicated by the blue arrows in the image?" "Apoptotic bodies" "Lipid droplets" "Granulomas" "Mitotic figures" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2389.jpg" -"2390" "In the histological sample, what is the cell abnormality that raises suspicion for a neoplastic process?" "Mononucleation with prominent nucleoli" "Binucleation" "Apoptotic bodies" "Multinucleation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2390.jpg" -"2391" "Regarding the extracellular matrix staining characteristics observed in the image, what conclusion can be drawn?" "The matrix is fibrous and stains intensely with eosin, which is typical for fibrous tissue" "The matrix presents as a light basophilic hue, characteristic of cartilage tissue" "The matrix has a dense eosinophilic staining indicative of muscle tissue" "The lack of staining in the matrix suggests a loose connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2391.jpg" -"2392" "What does the intense brown staining in the cells most likely indicate?" "Lipofuscin accumulation" "CD133 protein expression" "Glycogen presence" "Melanin accumulation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2392.jpg" -"2393" "Based on the image, how would you describe the tumor cell population?" "Homogenous with similar staining and morphology" "Heterogeneous with similar staining but dissimilar morphology" "Homogenous with dissimilar staining but similar morphology" "Heterogeneous with dissimilar staining and morphology" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2393.jpg" -"2394" "What does the presence of the dark-staining nuclei surrounding the granuloma most likely indicate?" "Fibrosis" "Healing and repair" "Active inflammation" "Necrosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2394.jpg" -"2395" "What distinctive morphology of the nuclei is visible in the larger cells?" "Hyperchromatic nuclei" "Multilobulated nuclei" "Prominent nucleoli" "Eccentrically placed nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2395.jpg" -"2396" "How would you describe the appearance of the smaller cells' nuclei?" "Dense and darkly stained" "Regularly shaped and lightly stained" "Bi-lobulated and eosinophilic" "Enlarged with prominent cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2396.jpg" -"2397" "What morphological feature observable in this image is indicative of a microfilaria?" "Long, coiled, thread-like structure without a distinct external sheath" "A segmented, rigid exoskeleton" "Presence of flagella for locomotion" "Sinuous body with a distinct external sheath" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2397.jpg" -"2398" "Considering the staining characteristics visible in the slide, with which stain is this blood smear most likely prepared?" "Acid-fast stain" "Wright's stain" "Hematoxylin and eosin (H&E) stain" "Giemsa stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2398.jpg" -"2399" "In image a, what is the predominant staining pattern observed within the cells?" "Uniform nuclear staining without cytoplasmic counterstain" "Cytoplasmic staining with non-specific background" "Peripheral cytoplasmic staining and clear central nuclei" "Mixed nuclear and cytoplasmic staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2399.jpg" -"2400" "In the context of this Hematoxylin & Eosin (H&E) stained tissue section, what might the presence of focal brown staining within small, narrow structures suggest?" "Abundant collagen deposition" "High levels of glycogen within the cells" "Accumulation of hemosiderin" "Presence of blood vessels highlighted by CD34 staining" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2400.jpg" -"2401" "Based on the cellular morphology visible at ×400 magnification, what type of cellular atypia is depicted in the epidermis?" "Presence of koilocytic changes" "Dysplastic nevus cells" "Increase in melanocytic activity" "Atypical lymphocytic infiltration" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2401.jpg" -"2402" "What histological feature in the image indicates an alteration in the skin's barrier function?" "Basal cell hyperplasia" "Hyperkeratosis" "Increased melanin deposition" "Spongiosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2402.jpg" -"2403" "What cellular characteristic is most prominent in the abnormal cells within the perineural spaces?" "Hyperchromatic nuclei" "Clear cytoplasm" "Vesicular nuclei with prominent nucleoli" "Monomorphic nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2403.jpg" -"2404" "Considering the overall tissue architecture, what is the pattern of growth observed in this image?" "Uniform, nodular growth" "Expansile, well-circumscribed growth" "Infiltrative, irregular growth" "Encapsulated, comedo-like growth" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2404.jpg" -"2405" "What observation can be made regarding the renal tubules' luminal space?" "The luminal space is uniformly expanded, suggesting tubular obstruction" "The tubules exhibit significantly reduced luminal space, consistent with atrophic changes" "Most of the tubules show no significant change in luminal space" "The tubules predominantly display dilated lumina indicative of high glomerular filtration rates" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2405.jpg" -"2406" "What is the predominant cell type observed in this tissue section?" "Giant cells with multiple nuclei" "Epithelioid cells with round nuclei" "Lymphocytes with hyperchromatic nuclei" "Spindle-shaped cells with elongated nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2406.jpg" -"2407" "What does the appearance of the nuclei within the spindle cells suggest about their chromatin pattern?" "A relatively euchromatic pattern" "An overly condensed, or pyknotic, chromatin pattern" "A clear pattern of heterochromatin" "A pattern indicative of karyorrhexis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2407.jpg" -"2408" "What is the morphological pattern of the brown-stained cells surrounding the 'V' structure?" "They are polygonal in shape" "They are round with central dark staining" "They are spindle-shaped and arranged in circular pattern" "They are elongated and arranged randomly" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2408.jpg" -"2409" "Approximately how many spindle-shaped cells can be observed around the central 'V' structure?" "Between 20 and 30" "Fewer than 10" "More than 30" "Between 10 and 20" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2409.jpg" -"2410" "In the given image, what does the brownish staining on some of the cells indicate?" "Accumulation of pigments within the cytoplasm" "Necrotic activity within cellular structures" "Presence of a specific antigen or protein on the cell surface" "High concentration of glycogen within the cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2410.jpg" -"2411" "Based on the tissue staining, which of the following can be inferred about the connective tissue underneath the epithelial layer?" "There is an absence of distinctly colored extracellular matrix, suggesting low levels of Alcian blue-reactive substances." "There is a presence of predominantly Alcian blue-reactive substances." "It contains a high concentration of elastic fibers." "It has an abundance of acidic polysaccharides." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2411.jpg" -"2412" "What morphological feature indicates the presence of myeloid lineage cells at various stages of maturation in the image?" "Cells with well-defined cytoplasmic granules" "Cells with abundant cytoplasm" "Cells with multilobed nuclei" "Small cells with scant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2412.jpg" -"2413" "Based on the image, which type of marrow cell can be characterized by having a large, vesicular nucleus?" "Megakaryocytes" "Lymphocytes or plasma cells" "Erythrocytes" "Myelocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2413.jpg" -"2414" "Based on the morphology of the cells within the dense cellular aggregates, which type of white blood cell predominates in this histological specimen?" "Neutrophils" "Monocytes" "Lymphocytes" "Eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2414.jpg" -"2415" "Based on the observed nuclear characteristics, how would you describe the chromatin pattern and nucleoli visibility in the cells?" "Condensed chromatin with no visible nucleoli" "Fine chromatin with prominent multiple nucleoli" "Fine chromatin with visible nucleoli" "Coarse chromatin with inconspicuous nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2415.jpg" -"2416" "Considering the growth pattern of the tissue, how would you characterize the overall tissue architecture?" "Organized growth with regular acini structures" "Markedly disorganized with no definite structure" "Lobular architecture with uniform acini distribution" "Papillary architecture with fibrovascular cores" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2416.jpg" -"2417" "What is the predominant staining characteristic of the large cells with pleomorphic nuclei in the image?" "Eosinophilic cytoplasm with pyknotic nuclei" "Deeply basophilic cytoplasm and nuclei" "Acidophilic cytoplasm with basophilic nuclei" "Clear cytoplasm with hyperchromatic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2417.jpg" -"2418" "What feature is indicated by the arrow in the image?" "Fibrovascular cores" "Apoptotic bodies" "Keratinization" "Abnormal mitotic figures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2418.jpg" -"2419" "Based on the image, what can be deduced regarding the nuclear features of the cells?" "Monomorphic nuclei with evenly distributed chromatin" "Uniform and small nuclei" "Hyperchromatic and pleomorphic nuclei" "Large nuclei with prominent nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2419.jpg" -"2420" "How would you describe the nuclear-to-cytoplasmic ratio in the cells shown in the image?" "Nuclear-to-cytoplasmic ratio typical of benign cells" "Inconclusive nuclear-to-cytoplasmic ratio due to poor staining" "High nuclear-to-cytoplasmic ratio" "Low nuclear-to-cytoplasmic ratio" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2420.jpg" -"2421" "Based on the observed staining patterns, which type of staining technique is most likely utilized in this histological image?" "Periodic acid–Schiff (PAS)" "Immunohistochemical (IHC)" "Masson's trichrome" "Hematoxylin and eosin (H&E)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2421.jpg" -"2422" "Which layer of the stratified squamous epithelium exhibits the most intense brown staining indicative of higher protein expression in this IHC stained section?" "Upper spinous layer" "Granular layer" "Horny layer (stratum corneum)" "Basal layer" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2422.jpg" -"2423" "Considering the homogeneous staining and cellular architecture, what does this image suggest about the proliferation status of cells in the stained regions?" "The cells in stained regions demonstrate features of hypoplasia" "The cells in stained regions are indicative of normal proliferation" "The cells in stained regions show evidence of hyperplasia" "The cells in stained regions exhibit signs of atrophy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2423.jpg" -"2424" "Based on the intensity and distribution of the nuclear staining, how would you describe the proliferative activity observed in this tissue sample?" "Almost all cells are uniformly showing high proliferative activity" "A moderate proportion of cells show signs of proliferative activity" "There is a high proportion of apoptotic cells rather than proliferative cells" "There is minimal to no proliferative activity indicated by the staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2424.jpg" -"2425" "What is the most likely nature of the large, clear spaces scattered throughout the less organized tissue on the left side of the image?" "Dilated vascular spaces" "Areas of necrosis" "Granuloma formations" "Mucinous lakes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2425.jpg" -"2426" "Based on the cellular morphology and arrangements observed in the image, which type of proliferative process is suggested on the left side of the image?" "Adenomatous proliferation" "Reactive or neoplastic proliferation" "Squamous cell proliferation" "Lymphoid proliferation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2426.jpg" -"2427" "In the image, what is the nature of the boundary between the epidermis and the dermis?" "There is a gradual transition with few cellular irregularities" "There is a lack of a clear boundary, indicating invasive growth" "The boundary is well-defined with regular architecture" "The boundary possesses a homogeneously organized fibrous texture" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2427.jpg" -"2428" "If assessing for granular cytoplasm, which of the following should not be observed in the cells as per this image?" "Scant cytoplasm with few granules" "A thick and uniform cytoplasmic texture" "Dense cytoplasmic granularity" "Abundant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2428.jpg" -"2429" "What is the likely nature of the lighter pink cytoplasm cells present within the arterial wall?" "Adipocytes" "Myocytes" "Keratinizing squamous cells" "Neutrophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2429.jpg" -"2430" "Based on the morphology seen in the right portion of the image, what could be the likely composition of the less densely stained region?" "Wharton's jelly" "Dense fibrous connective tissue" "Hyaline cartilage" "Adipose tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2430.jpg" -"2431" "The surrounding cells not marked by the arrow are most likely which of the following?" "Myocytes" "Tumor Cells" "Mature Red Blood Cells" "Inflammatory Cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2431.jpg" -"2432" "What is the predominant staining characteristic of the intracellular bodies suspected to be Leishmania spp. amastigotes in this lymph node sample?" "They have a pale cytoplasm and a barely visible nucleus." "They appear as dense, darkly staining nuclei with a compact appearance." "They show a multi-lobed nucleus with a basophilic cytoplasm." "They are staining lightly and have a diffuse nuclear pattern." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2432.jpg" -"2433" "How does the background matrix of the sample predominantly appear in terms of staining properties?" "It is lightly basophilic with a granular appearance." "It is heavily basophilic with a crystalline structure." "It is eosinophilic with a fibrous appearance." "It is neutrophilic with an amorphous structure." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2433.jpg" -"2434" "Based on the cytoplasmic staining pattern observed in the cells indicated by arrows, what is the most likely morphology of the cells?" "Rounded with distinct cell borders" "Spindle-shaped with tail-like extensions" "Cuboidal with central nuclei" "Irregular with multiple nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2434.jpg" -"2435" "What can be inferred about the renal tubules based on the image provided?" "The tubules demonstrate pronounced inflammation" "The tubules show clear spaces surrounded by simple cuboidal epithelium" "Tubules contain an eosinophilic substance in their lumen" "Tubules are surrounded by dense connective tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2435.jpg" -"2436" "Based on the contents of the image, which statement accurately describes the extracellular matrix and stromal components observed within the renal tissue?" "Hyaline deposition around the tubules and glomeruli" "Extensive hemorrhage in the interstitial matrix" "Faintly visible with no significant details discernible" "Dense fibrosis throughout the interstitial areas" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2436.jpg" -"2437" "Which component is predominantly present in the larger empty-looking spaces within the tissue section observed in the microscopic image?" "Keratinized cells" "Blood cells" "Myelinated nerve fibers" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2437.jpg" -"2438" "Based on the structure indicated by the yellow arrow, what are the typical morphological characteristics of the endothelial cells lining the vessel-like structure?" "Irregularly shaped and disorganized" "Short and squamous" "Tall and plump" "Flattened and elongated" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2438.jpg" -"2439" "Assessing the nuclei of the cells surrounding the central lumen, what cytological feature is prominent?" "Binucleation" "Hyperchromasia" "Anisonucleosis" "Multinucleation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2439.jpg" -"2440" "What is the morphology of the structures present within the lumens of some renal tubules?" "Amorphous casts with granular texture" "Polygonal crystals with sharp edges" "Leukocytes with lobed nuclei" "Erythrocytes with biconcave disc shape" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2440.jpg" -"2441" "What does the presence of pink-stained extracellular matrix surrounding the glandular formation in the image most likely indicate?" "Extensive necrosis typical of aggressive malignancies" "Abundant amyloid deposits often seen in amyloidosis" "Dense connective tissue stroma common in fibroadenomas" "Vascular proliferation characteristic of angiosarcomas" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2441.jpg" -"2442" "Based on the intracytoplasmic pigmentation visible in the cells, which pigment is most likely present?" "Melanin" "Hemoglobin" "Lipofuscin" "Hemosiderin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2442.jpg" -"2443" "What cellular morphology is predominantly observed in this image?" "Spherical cells with a small cytoplasmic ratio" "Irregularly shaped cells with abundant cytoplasm" "Spindle-shaped cells" "Cuboidal cells with a central nucleus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2443.jpg" -"2444" "The nuclei of the cells observed in this field mostly show which of the following features?" "Hyperchromatic with coarse chromatin" "Multilobed with dense chromatin" "Nucleoli that are prominent" "Anisonucleosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2444.jpg" -"2445" "Based on the cells present in the dermis, what is the most likely type of infiltrate observed?" "Histocytic infiltrate" "Eosinophilic infiltrate" "Neutrophilic infiltrate" "Lymphocytic infiltrate" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2445.jpg" -"2446" "What is the condition of the stratum corneum in this skin biopsy?" "Displays signs of hyperkeratosis" "Exhibits parakeratosis" "Appears relatively normal" "Shows atrophy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2446.jpg" -"2447" "What distinctive cytological feature can be observed in the cells present in this tissue section?" "Signet ring cell morphology" "Multinucleation with nuclear molding" "Dense cytoplasmic keratin pearls" "Cytoplasmic halo with perinuclear clearing" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2447.jpg" -"2448" "What is the significance of the brown pigment found in the cytoplasm of several cells within both the epidermis and dermis?" "It indicates normal melanin production" "It reflects the presence of hemosiderin due to hemorrhage" "It is a staining product indicating the presence of a particular antigen" "It is a sign of benign melanocytic proliferation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2448.jpg" -"2449" "What feature in the main image is consistent with the presence of plasma cells?" "Cells with large, lobulated nuclei" "Cells with more abundant cytoplasm" "Cells with dense granules in the cytoplasm" "Cells with scant cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2449.jpg" -"2450" "In the inset immunohistochemical stain, what does the brown cytoplasmic staining in certain cells indicate?" "Overexpression of cyclin D1" "Expression of the CD3 antigen" "Expression of the CD20 antigen" "Presence of neutrophil elastase" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2450.jpg" -"2451" "Upon examination of the liver tissue under a microscope, you observe an area with cells that have an eccentrically placed nucleus and abundant cytoplasm. In this context, what type of cells are most likely represented by this description?" "Hepatocytes" "Endothelial cells" "Plasma cells" "Kupffer cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2451.jpg" -"2452" "What is the predominant feature of this glomerulus observed under the microscope?" "Crescent formation with increased cellularity" "Normal glomerular architecture with minimal changes" "Sclerosis with significant hyaline deposition" "Global glomerulosclerosis affecting entire glomerular tuft" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2452.jpg" -"2453" "What does the staining pattern in the image suggest about the intracellular content of the cells?" "Rich in RNA content" "Presence of certain antigens" "High lipid content" "Abundant glycogen storage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2453.jpg" -"2454" "Based on the microscopic characteristics, what is the nature of the topmost layer's eosinophilic material?" "Hyaline cartilage" "Necrotic debris" "Collagen deposition" "Apoptotic remnants of blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2454.jpg" -"2455" "What does the presence of aligned collagen fibers and elongated fibroblasts in the bottom layer suggest about the tissue's healing stage?" "Early reparative phase" "Acute inflammation" "Presence of granulation tissue" "Advanced fibrotic remodeling" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2455.jpg" -"2456" "Which layer in the image represents stratified squamous epithelium?" "The layer with vacuolated spaces" "The layer with dense, homogeneous, eosinophilic texture" "The layer with elongated spindle-shaped cells with elongated nuclei" "The layer with clusters of cells containing more eosinophilic cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2456.jpg" -"2457" "In the image provided, where can smooth muscle tissue be identified?" "The area with large empty-looking spaces" "The most superficial layer in the image" "The layer directly below the vacuolated spaces" "The region surrounding the glandular structures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2457.jpg" -"2458" "What is the predominant chromatin pattern observed in the nuclei of the lymphoid cells in this image?" "Compact with inconspicuous nucleoli" "Clumped at the nuclear periphery with a prominent nucleolus" "Vesicular with prominent nucleoli" "Open with clearly visible multiple nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2458.jpg" -"2459" "How would you classify the staining quality of the cytoplasm of these lymphoid cells?" "Basophilic" "Eosinophilic" "Amphophilic" "Neutrophilic" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2459.jpg" -"2460" "Regarding the morphology of the filamentous structures, which description best fits the observed features?" "Thick, unbranching, and without regular septations" "Thin, branching, and with irregular septations" "Lightly stained, unbranching, and with wide, irregular septations" "Darkly stained, branching, and with regular septations" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2460.jpg" -"2461" "By analyzing the cellular morphology, what is the cytoplasmic staining characteristic in the clusters of cells?" "Melanin accumulation" "Glycogen deposition" "Lipofuscin pigmentation" "Hemosiderin deposition" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2461.jpg" -"2462" "What can be inferred about the nuclei of the spindle-shaped, brown-staining cells?" "They are pleomorphic" "They are obscured by the staining" "They are enlarged and prominent" "They are hyperchromatic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2462.jpg" -"2463" "What feature does the black arrow indicate in this hematoxylin and eosin-stained section of colorectal tissue?" "Abnormal mitotic figures within the epithelial cells" "Evidence of crypt abscess formation" "Presence of neutrophils within the crypt lumens" "Increased number of intraepithelial lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2463.jpg" -"2464" "What pathological condition does the red arrow in the image suggest about the colorectal tissue?" "Suggestion of increased intraepithelial neutrophil count" "Indication of muscularis mucosae hypertrophy" "Presence of a thickened subepithelial collagen layer" "Evidence of neutrophilic infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2464.jpg" -"2465" "How would you describe the location of the nuclei within these skeletal muscle fibers?" "Peripheral" "Dispersed throughout the cytoplasm" "Absent" "Central" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2465.jpg" -"2466" "How would you describe the nuclei of the cells that are not the target of the immunostain?" "Multinucleated with dense chromatin" "Small, hypochromatic with smooth contours" "Pale blue, round to oval with visible nucleoli" "Large, hyperchromatic with irregular borders" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2466.jpg" -"2467" "Based on the staining characteristics, what does the presence of red-stained rod-shaped bacteria suggest?" "Gram-positive cocci" "Acid-fast bacilli" "Gram-negative bacilli" "Non-acid-fast bacilli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2467.jpg" -"2468" "What can be inferred about the distribution of the bacilli within the tissue from this image?" "The bacilli are primarily located in one area" "The bacilli are evenly distributed" "There are no visible bacilli" "The bacilli are randomly scattered" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2468.jpg" -"2469" "What is the nature of the cytoplasmic inclusions observed in some of the cells in the image?" "Hemosiderin deposits that are golden brown and granular" "Glycogen deposits that are clear and unstained" "Lipid droplets that are clear and vacuolated" "Melanin pigment that is granular and dark brown to black" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2469.jpg" -"2470" "Based on the organization and morphology of the cells, how would you characterize the tissue architecture?" "Densely cellular with extensive intervening stroma" "Densely cellular with little to no intervening stroma" "Spindle-shaped cells arranged in fascicles with abundant stroma" "Loosely arranged cells with abundant extracellular matrix" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2470.jpg" -"2471" "What is the predominant morphological characteristic of the larger cells containing the internalized lymphocytes within their cytoplasm?" "Hyperchromatic and pleomorphic nuclei" "Single, central, hyperchromatic nucleus" "Abundant eosinophilic cytoplasm" "Multiple nuclei with conspicuous nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2471.jpg" -"2472" "What is the degree of differentiation of the neoplasm observed in the tissue?" "Cannot determine" "Well-differentiated" "Poorly differentiated" "Moderately differentiated" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2472.jpg" -"2473" "When closely observing the cytoplasmic features in this microscopic view, what is the most accurate description of the cytoplasm?" "Abundant cytoplasm with granular appearance and well-delineated borders" "Copious and eosinophilic cytoplasm with clearly defined cell borders" "Scant and basophilic cytoplasm with indistinct cell borders" "Moderate to abundant basophilic cytoplasm with vacuolations" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2473.jpg" -"2474" "Considering the extracellular matrix visible in the image, what is its appearance and likely composition?" "A fibrillar basophilic matrix typical of cartilaginous tissue" "A dense eosinophilic matrix consistent with collagen bundles" "An eosinophilic extracellular matrix characteristic of supportive stroma of bone marrow tissue" "A loose, myxoid matrix commonly found in soft tissue tumors" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2474.jpg" -"2475" "What is the predominant staining characteristic of the extracellular matrix in this image?" "Eosinophilic with a glassy, homogenous appearance" "Basophilic with a rigid, crystalline structure" "Eosinophilic with a fibrous, reticular pattern" "Mucinous with a blue, heterogeneous appearance" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2475.jpg" -"2476" "How would you describe the arrangement of collagen bundles in this tissue sample?" "Interspersed haphazardly without uniform pattern" "Organized in parallel arrays" "Arranged in a whorled pattern" "Concentrated around a central point forming a nodule" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2476.jpg" -"2477" "Based on the cellular morphology observed, what is the likely nature of the process involving these cells?" "Malignant neoplasm" "Benign hyperplasia" "Acute inflammatory process" "Normal tissue homeostasis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2477.jpg" -"2478" "How would you describe the level of expression of the target antigen based on the staining intensity?" "High level of expression" "Moderate level of expression" "Intermittent expression across the sample" "Low level of expression" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2478.jpg" -"2479" "Identify the cells that display round nuclei with dense chromatin pattern and scant cytoplasm in the image." "Erythroblasts" "Myeloblasts" "Basophils" "Lymphocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2479.jpg" -"2480" "The small, circular, and pale-staining cells in the background of this image are likely to be what type of blood cells?" "Platelets" "Lymphocytes" "Erythrocytes" "Monocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2480.jpg" -"2481" "By observing the extracellular matrix texture indicated with an asterisk, what composition is suggested?" "Compact bone matrix" "Fibrocartilage matrix" "Dense elastic fibers" "Hyaline cartilage matrix" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2481.jpg" -"2482" "What can be deduced about the nuclear-to-cytoplasmic ratio from this high magnification image of cells stained with Hematoxylin and Eosin?" "A constant nuclear-to-cytoplasmic ratio throughout the field" "A decreased nuclear-to-cytoplasmic ratio" "An increased nuclear-to-cytoplasmic ratio" "A variable nuclear-to-cytoplasmic ratio across the field" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2482.jpg" -"2483" "What is the predominant cytoplasmic characteristic of the cells observed in the image?" "Abundant clear cytoplasm" "Granular basophilic cytoplasm" "Scanty cytoplasm with prominent vacuolation" "Dense eosinophilic cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2483.jpg" -"2484" "Considering the nuclear characteristics, how would you classify the chromatin appearance of the majority of cell nuclei in the image?" "Chromatin displaying prominent nucleoli" "Uniformly dispersed chromatin" "Nuclei with visible inclusions" "Hyperchromatic nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2484.jpg" -"2485" "What does the pink-stained matrix observed in the image predominantly represent?" "Vascular tissue" "Adipose tissue" "Neural tissue" "Fibrous connective tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2485.jpg" -"2486" "Analyzing the distribution of nuclei in the lobular structures, what histological pattern is suggested by the presence of lighter-staining areas within these lobules?" "Infiltration of lymphocytes" "Hyaline degeneration" "Necrotic tissue" "Serous atrophy" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2486.jpg" -"2487" "What is the predominant cell type observed in this microscopic image based on their morphology?" "Erythrocytes" "Neutrophils" "Lymphocytes" "Eosinophils" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2487.jpg" -"2488" "How would you describe the appearance of the nuclei of the larger atypical cells seen in the image?" "Oval with a visible nucleolus" "Multilobed with clumped chromatin" "Round with dense chromatin" "Vacuolated with dispersed chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2488.jpg" -"2489" "What cell type appears to predominate the center of this microscopic field?" "Epithelioid cells" "Erythrocytes" "Fusiform fibroblasts" "Squamous epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2489.jpg" -"2490" "In assessing tissue cohesiveness in this image, what can be inferred about the cellular arrangement?" "Cells exhibit a high degree of cohesiveness with organized structure" "Cells are well-differentiated with distinct cell boundaries" "Cells align in duct-like structures, suggesting organized epithelial origin" "Cells demonstrate lack of cohesiveness with disorganized structure" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2490.jpg" -"2491" "How would you describe the overall pattern of the round structures within the field?" "Organized in clusters" "Lined along the tissue structure" "Randomly distributed" "Forming a rosette pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2491.jpg" -"2492" "The eosinophilic substance within which the encapsulated structures are scattered is most likely:" "Acute inflammatory exudate" "Necrotic debris" "Normal healthy tissue" "Hyaline cartilage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2492.jpg" -"2493" "In the context of inflammatory reactions, what feature is evident in this tissue section?" "Decreased vascularization in the connective tissue." "Presence of numerous plasma cells within the stroma." "Formation of sporangia without any surrounding inflammatory cells." "Accumulation of eosinophils around cyst-like structures." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2493.jpg" -"2494" "Based on the observation of the surface epithelium in the image, which type of epithelium is present?" "Pseudostratified ciliated columnar epithelium" "Simple columnar epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2494.jpg" -"2495" "What is the histological feature of the organized cell collections within the underlying stroma?" "Multinucleated giant cells" "Caseating granulomas" "Neoplastic cells" "Epithelioid histiocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2495.jpg" -"2496" "Considering the cells indicated by the black arrows, which have scant cytoplasm, what can be inferred about their stage of development?" "They represent mature leukocytes" "They are at an early stage of hematopoietic cell development" "They are indicative of megakaryocytes" "They are mature erythrocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2496.jpg" -"2497" "What are the histological characteristics of the cells labeled '1' in the image?" "They exhibit prominent nucleoli and increased cytoplasmic basophilia" "They show evidence of high mitotic activity with atypical mitoses" "They contain abundant eosinophilic cytoplasm with plump nuclei" "They demonstrate abundant melanin pigment within the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2497.jpg" -"2498" "Based on their morphology and location in this H&E stained section, what is the function of the cells indicated by label '3'?" "These cells are involved in the production of new keratinocytes" "Their primary role is the synthesis and storage of lipids" "They function as melanophages, ingesting melanin pigment" "They are responsible for synthesizing collagen and extracellular matrix components" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2498.jpg" -"2499" "Based on the cellular morphology visible in the image, what staining technique is most likely used in this microscopic view?" "Masson's trichrome stain" "Hematoxylin and Eosin (H&E) stain" "Periodic acid-Schiff (PAS) stain" "Giemsa stain" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2499.jpg" -"2500" "Based on the morphology and staining pattern in this image, which type of cell population is most likely represented here?" "Neuronal cell population with neurodegenerative changes" "Epithelial cell population with signs of metaplasia" "Myeloid cell population with dysplastic features" "Lymphoid cell population with reactive immunophenotype" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2500.jpg" -"2501" "How would you describe the nuclei of the infiltrating blasts in the dermis?" "Anisonucleosis with prominent nucleoli" "Macrochromatic with rare mitoses" "Euploid with small nucleoli" "Hyperchromatic with a high nuclear-to-cytoplasmic ratio" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2501.jpg" -"2502" "Which feature would likely belong to a microglia cell in the dentate gyrus of the hippocampus as visualized in this H&E stained section?" "Cells with abundant basophilic cytoplasm" "Rounded cells with vesicular nuclei" "Cells with darkly stained, pyknotic nuclei" "Rod-shaped nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2502.jpg" -"2503" "In frame A, what is the predominant localization of the brown staining within the cells?" "Cytoplasm" "Extracellular matrix" "Cell membrane" "Nucleus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2503.jpg" -"2504" "Based on the immunohistochemical staining patterns observed in frames A and B, which type of light chain expression is most likely indicated?" "Polyclonal kappa and lambda light chain expression" "Monoclonal kappa light chain expression" "Monoclonal lambda light chain expression" "Polyclonal kappa light chain expression" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2504.jpg" -"2505" "What do the cells at the bottom of the image with large oval nuclei and abundant eosinophilic cytoplasm most likely represent?" "Mature squamous cells" "Lymphocytes" "Columnar epithelial cells" "Hepatocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2505.jpg" -"2506" "What can be inferred regarding the cellularity within the mesangial areas based on the microscopic image?" "Complete absence of cells" "Decreased cellularity" "Normal cellularity" "Hypercellularity" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2506.jpg" -"2507" "Based on the observed staining patterns, which immune reactant does not appear to be present in the glomerular tissue?" "C1q" "IgA" "IgG" "IgM" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2507.jpg" -"2508" "What observation supports the presence of increased protein synthesis or cytoplasmic changes in some cells of this brain tissue section?" "Deeply eosinophilic cytoplasm" "Pale-staining cytoplasm with a granular texture" "Copious cytoplasm with clear vacuolation" "Scant cytoplasm with intense basophilic staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2508.jpg" -"2509" "Which of these features is not consistent with the normal histology of the liver tissue observed in this image?" "Central basophilic nuclei in hepatocytes" "Dense and unstructured cellular clusters" "Eosinophilic (pink) cytoplasm in hepatocytes" "Organized plates of hepatocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2509.jpg" -"2510" "What does the presence of open clear spaces in this hepatic tissue suggest?" "Areas of necrosis or lipid accumulation" "Dilation of hepatic blood vessels" "Area of active fibrogenesis" "Normal sinusoidal spaces" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2510.jpg" -"2511" "Based on the morphology, what is true regarding the capillaries within the glomerular tuft?" "Capillaries with thickened walls and evident hyalinosis" "Capillaries with poorly discernible lumens likely due to compression" "Capillaries with clearly visible and patent lumens" "Capillaries with significant infiltration of neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2511.jpg" -"2512" "Based on the whorl formations observed in the image, which type of brain tumor is most likely represented here?" "Pituitary adenoma" "Meningioma" "Medulloblastoma" "Glioblastoma multiforme" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2512.jpg" -"2513" "Considering the chromatin pattern within the nuclei in this field of view, how would you describe it?" "Very light staining with numerous small nucleoli" "Moderately dense with some visible nucleoli" "Highly dispersed with prominent macronucleoli" "Highly clumped with no visible nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2513.jpg" -"2514" "Which type of cells predominate in the examined tissue based on their morphological characteristics?" "Neutrophils" "Lymphocytes" "Basophils" "Eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2514.jpg" -"2515" "What feature indicates the presence of vascular damage within the tissue?" "Clear, well-defined vascular walls without any evidence of infiltrates" "Presence of leukocytoclastic debris" "Areas of deeper pink to red staining within vascular structures" "Evidence of increased eosinophil infiltration" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2515.jpg" -"2516" "What feature is observed in the eosinophilic bodies seen in this hepatic tissue?" "Presence of necrotic material" "Infiltration of immune cells" "Abundance of mitochondria" "High lipid content" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2516.jpg" -"2517" "What is the most likely identity of the cell highlighted by the green arrow in the image provided?" "Neutrophil" "Eosinophil" "Macrophage" "Lymphocyte" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2517.jpg" -"2518" "Which characteristic of the cells infiltrating the left part of the tissue section is indicative of a particular cell type commonly found in reactive or inflammatory conditions?" "Presence of spindle-shaped cells" "Presence of multinucleated giant cells" "Presence of cells with foamy cytoplasm" "Presence of cells with granular cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2518.jpg" -"2519" "Based on the staining pattern, which feature of the cells' nuclei is the most evident?" "Nuclear hyperchromasia" "Non-expression of vimentin" "High metabolic activity" "Multinucleation" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2519.jpg" -"2520" "What morphological feature best characterizes the elastic fibers visible in this histological section?" "Smooth, continuous fibers" "Fragmented and clumped structures" "Regularly branching networks" "Broad, ribbon-like bands" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2520.jpg" -"2521" "The background matrix in which the elastic fibers are embedded is primarily stained what color?" "Blue" "Yellow" "Pink to light red" "Green" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2521.jpg" -"2522" "Based on the cellular morphology shown in the image, what is an absent feature that might be expected in other proliferative conditions?" "Abundant eosinophilic cytoplasm" "Multinucleated cells" "Readily apparent mitotic figures" "Prominent nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2522.jpg" -"2523" "Based on the microscopic characteristics, what does the tissue likely indicate?" "Normal renal parenchyma without any significant pathology" "Renal tissue with signs of acute tubular necrosis" "Renal tissue showing changes consistent with an inflammatory response" "Renal tissue indicative of advanced diabetic nephropathy" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2523.jpg" -"2524" "What is the predominant nuclear feature observed in the displayed tissue?" "Multinucleation" "Uniform chromatin distribution" "Hyperchromatic nuclei" "Monomorphic nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2524.jpg" -"2525" "Based on the microscopic characteristics, what is the most likely diagnosis of the tissue in the image?" "Adenocarcinoma" "Benign prostatic hyperplasia" "Chronic inflammation with glandular atrophy" "Atrophic glandular tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2525.jpg" -"2526" "In terms of histopathological diagnosis, what does the presence of a prominent, dense stromal component surrounding the glandular structures in the image suggest?" "Benign stromal proliferation" "Desmoplastic reaction" "Stromal invasion by malignant cells" "Chronic inflammation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2526.jpg" -"2527" "Regarding the eosinophilic amorphous material deposits, where is this pathology predominantly visible?" "Throughout the tubular epithelium, sparing the glomeruli." "Exclusively within the glomerular capillaries." "Limited to the vascular pole of the glomeruli." "Within both the glomeruli and the expanded interstitium." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2527.jpg" -"2528" "Based on the histological features observed in the image, what type of epithelial cells predominantly comprises the uppermost layer of the tissue?" "Pseudostratified columnar epithelial cells" "Transitional epithelial cells" "Squamous epithelial cells" "Simple columnar epithelial cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2528.jpg" -"2529" "The stromal compartment contains structures indicative of which type of tissue components?" "Adipose tissue" "Nerve fibers" "Cartilage" "Small blood vessels" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2529.jpg" -"2530" "Based on the uniformity and eccentric placement of the nuclei within the cells, what is the most probable cytological characteristic these cells exhibit?" "Anaplasia" "Hyperchromatism" "Monomorphism" "Pleomorphism" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2530.jpg" -"2531" "Considering the granularity of the cytoplasm, which of the following cell types does this microscopic image most closely resemble?" "Plasma cells" "Lymphocytes" "Neutrophils" "Monocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2531.jpg" -"2532" "What is the predominant staining pattern observed in the cytoplasm of the cells?" "Prominent brown staining" "Light green staining" "Dark blue basophilic staining" "Reddish-pink eosinophilic staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2532.jpg" -"2533" "What does the blue coloration of the cell nuclei suggest about the staining technique used?" "The technique uses a fluorescence tag for DNA strands" "The technique preferentially stains the cell's lipid content" "The technique targets proteins in the cytoplasm, not the DNA in the nucleus" "The technique is a silver stain highlighting reticular fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2533.jpg" -"2534" "Based on the observable morphology and staining characteristics, what cell type do these characteristics resemble most closely?" "Adipocytes with prominent lipid vacuoles" "Astrocytic cells with fibrillary networks" "Skeletal muscle cells with cross-striping" "Hepatocytes with glycogen storage" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2534.jpg" -"2535" "How would you describe the pattern of the eosinophilic structures surrounding the basophilic deposits?" "Uniformly dense and compacted" "Swirling with parallel lines and bundles" "Mostly loose with scattered fibrils" "Disorganized and fragmented" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2535.jpg" -"2536" "What nuclear feature is notably visible in the cells within the papillary structures?" "Nuclear grooves" "Multinucleation" "Prominent nucleoli" "Smudged chromatin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2536.jpg" -"2537" "How would you describe the appearance of some of the nuclei observed in this microscopic image?" "Vesicular with marginated chromatin" "Optically clear" "Enlarged with perinuclear halos" "Hyperchromatic with prominent nucleoli" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2537.jpg" -"2538" "Considering the cellular arrangement and the visualized nuclei, which of the following options is most consistent with the features observed in this image?" "Crowded and overlapping nuclei" "Nuclear uniformity and roundness" "Cells arranged in a follicular pattern with colloid" "Cytoplasm with abundant granularity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2538.jpg" -"2539" "What characteristic feature of the keratinized stratified squamous epithelium is most prominent in the image?" "Hypergranulosis" "Parakeratosis" "Acantholysis" "Spongiosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2539.jpg" -"2540" "Analyzing the same image, what pathological condition does the blue arrow indicate within the epidermal layer?" "Acantholysis" "Spongiosis" "Psoriasiform hyperplasia" "Hypergranulosis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2540.jpg" -"2541" "What is the predominant location of the intracytoplasmic inclusions indicated by the arrows within the jejunal mucosal epithelial cells?" "Concentrated near the intercellular spaces" "Along the apical border" "At the basal region" "Scattered throughout the cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2541.jpg" -"2542" "What is the most likely composition of the pale, eosinophilic material within the irregular, dilated vascular-like spaces?" "Malignant cellular debris" "Purulent inflammatory cells" "Hemorrhagic exudate" "Chylous fluid" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2542.jpg" -"2543" "What is the likely identity of the scattered cells with round to oval nuclei observed throughout the stroma?" "Fibroblasts" "Neutrophils" "Endothelial cells" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2543.jpg" -"2544" "What is the most prominent feature of the large cell at the center of the image?" "It exhibits a single layer of peripheral nuclei" "It has a single, centralized nucleus" "It contains multiple nuclei organized in a circular manner" "It is devoid of any visible nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2544.jpg" -"2545" "Assessing the histological section, what can be inferred about the surrounding stroma?" "The stroma exhibits normal histological architecture" "The stroma appears disrupted and infiltrated by inflammatory cells" "The stroma shows signs of acellular mucinous material" "The stroma displays extensive fibrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2545.jpg" -"2546" "What is the predominant inflammatory cell type visible in the tissue section?" "Neutrophils" "Basophils" "Lymphocytes" "Eosinophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2546.jpg" -"2547" "Based on the morphological characteristics observed, what is the most likely composition of the spindle-shaped cells in this tissue section?" "Fibroblasts with collagen production" "Neurons with Nissl substance" "Cardiomyocytes with striations" "Smooth muscle cells with intercalated discs" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2547.jpg" -"2548" "What does the appearance of the tubules suggest?" "Tubules are lined by hyperplastic epithelial cells" "Tubules are well-formed with a clear lumen" "Uniform cell lining without any irregularities" "Presence of intraluminal proteinaceous material" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2548.jpg" -"2549" "What does the stroma with fibrous tissue running diagonally through the image suggest about the tissue architecture?" "Indication of tissue injury repair" "Partitions that may define different regions or lobules within the tissue" "Presence of inflammation" "Normal variation in cell distribution" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2549.jpg" -"2550" "Based on the observation of tissue architecture, what is the most likely condition affecting the tissue?" "Neoplastic or aggressive pathological process" "Normal healing process" "Inflammatory disease such as osteomyelitis" "Osteoporotic degeneration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2550.jpg" -"2551" "What is the arrangement of nuclei within the giant cells observed in this tissue sample?" "Uniformly distributed at the periphery of the cytoplasm" "Random dispersion throughout the cytoplasm" "Arranged in a peripheral arc-like or horseshoe pattern" "Centralized around a single point, reminiscent of a flower" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2551.jpg" -"2552" "What is the predominant architectural feature visible in this histological section?" "Solid tumor nests" "Cystic spaces lined by flattened epithelium" "Glandular structures with central lumens" "Papillary formations with fibrovascular cores" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2552.jpg" -"2553" "How would the nuclear features of the lining cells of the papillary structures best be described?" "Small, hyperchromatic nuclei with high mitotic activity" "Uniform nuclei with fine chromatin" "Uniform, round nuclei with single nucleoli" "Enlarged, pleomorphic nuclei with hyperchromasia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2553.jpg" -"2554" "Considering the integrity of the hepatic architecture, which histological feature is NOT observed within this field of view?" "Multinucleated giant cell" "Bridging fibrosis" "Eosinophilic cytoplasm of hepatocytes" "Central round nuclei of hepatocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2554.jpg" -"2555" "In section 'a' of the image, what cell type is indicated by the blue arrows?" "Myelocytes" "Lymphocytes" "Eosinophils" "Basophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2555.jpg" -"2556" "Based on the observation of section 'a' in the image, what feature is most characteristic of the cells circled in red?" "Red-orange granules" "Lack of prominent nucleoli" "Dense blue-purple granules" "Multilobed nucleus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2556.jpg" -"2557" "What predominant cellular morphology is observed in the tissue section?" "Spindle-shaped Schwann cells" "Round lymphocytes" "Cuboidal epithelial cells" "Columnar epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2557.jpg" -"2558" "What feature does the arrow in the image specifically point to?" "A focus of Schwann cell proliferation" "A region of necrosis" "A blood vessel" "An area of fatty infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2558.jpg" -"2559" "What can be inferred about the nuclear-to-cytoplasmic ratio observed in these cells?" "The nuclei and the cytoplasm are approximately equal in volume." "The nuclei are sparse within an abundant cytoplasm." "The nuclei occupy a larger proportion of the cell's volume compared to the cytoplasm." "The nuclei occupy a small proportion of the cell's volume." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2559.jpg" -"2560" "What is the nature of the nuclear contours in the cells present in this image?" "Coarse and clumped" "Irregular and not uniform" "Smooth and well-defined" "Regular and geometric" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2560.jpg" -"2561" "The cytoplasm of the cells in this image appears to be..." "Transparent and voluminous" "Equally proportionate to the nuclei" "Abundant and overshadowing the nuclei" "Scant and eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2561.jpg" -"2562" "In the insert with the increased magnification, how are the nuclei of the cells with prominent brown staining described?" "The nuclei are not visible, completely obscured by the brown staining." "The nuclei are light and uniform in color with a polygonal shape." "The nuclei are hyperchromatic and irregularly shaped with indistinct boundaries." "The nuclei are visible as darker, round to ovoid structures within the cell." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2562.jpg" -"2563" "Based on the density and distribution of eosinophils within the subepithelial tissue, what is the most likely pathological process occurring in this tissue?" "Neoplastic transformation" "Granulomatous inflammation" "Acute inflammation" "Chronic inflammation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2563.jpg" -"2564" "What feature in the cells indicates the possible presence of intracellular substances consistent with bile?" "The presence of clear vacuoles within the cytoplasm" "The uniform staining intensity of the cytoplasm" "The presence of multilobed nuclei" "The presence of a brownish pigmentation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2564.jpg" -"2565" "Analyzing the morphology of the cells situated in the dermis, specifically within the papillary dermis layer, how would you describe their shape?" "Spheroidal" "Spindle-shaped" "Cuboidal" "Columnar" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2565.jpg" -"2566" "Which histological feature is predominantly observed in the central portion of the renal corpuscle in the image?" "Mesangial cells" "Podocytes" "Macula densa cells" "Distal convoluted tubular cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2566.jpg" -"2567" "How would you characterize the nuclear chromatin pattern observed in the tissue sample?" "Condensed, irregular chromatin without visible nucleoli" "Open chromatin with prominent nucleoli" "Hyperchromatic, with variable nuclear sizes" "Homogeneous chromatin with small nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2567.jpg" -"2568" "What is the predominant shape of the nuclei in the epithelial cells lining the tubular structures?" "Large and vesicular with prominent nucleoli" "Small and pyknotic" "Round and centrally located" "Elongated and hyperchromatic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2568.jpg" -"2569" "What type of epithelium is depicted in the glandular structures based on the cellular arrangement?" "Cuboidal epithelium" "Columnar to pseudostratified epithelium" "Squamous epithelium" "Transitional epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2569.jpg" -"2570" "Assessing the glandular architecture, which of the following best classifies the observed features?" "Disordered, yet maintaining glandular differentiation without invasive growth" "Uniform glandular formation with minimal atypical architecture" "Highly irregular growth with severe cytological atypia" "Branching and irregular tubular structure with mild cellular atypia" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2570.jpg" -"2571" "Upon examining the dermal-epidermal junction, what architectural changes can be observed?" "Loss of rete ridges and a smooth junction" "Shortened and blunted rete ridges" "Rete ridges with branching and anastomosis" "Elongated rete ridges with a 'sawtooth' appearance" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2571.jpg" -"2572" "Based on the tissue's morphological features, what can be inferred about the presence and arrangement of nuclei within the muscle fibers?" "No visible nuclei within the muscle fibers" "Multiple nuclei within individual muscle fibers" "Centrally located nuclei within the muscle fibers" "Peripheral nuclei within the muscle fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2572.jpg" -"2573" "What is the morphology of the muscle fibers as observed in the histological section?" "Round to polygonal with distinct boundaries" "Spindle-shaped with tapering ends" "Branched and interconnected" "Irregular with diffuse borders" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2573.jpg" -"2574" "Based on the observed histological features, which statement accurately reflects the condition of the muscle tissue?" "A significant amount of connective tissue between fibers is present, consistent with fibrotic changes" "The section shows extensive necrosis and inflammatory cell infiltration" "The muscle fibers are uniform in size and shape, indicating a healthy muscle tissue" "There are variations in the size and shape of the muscle fibers within the same bundle" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2574.jpg" -"2575" "What type of inflammatory cell infiltration is primarily indicated by the blue arrows in the glandular structures?" "Neutrophils" "Macrophages" "Eosinophils" "Lymphocytes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2575.jpg" -"2576" "What is the most likely identification of the cells indicated by the arrows, based on the dark brown cytoplasmic or membrane-associated staining pattern?" "Fibroblasts" "Neoplastic cells" "Endothelial cells" "Macrophages" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2576.jpg" -"2577" "What cellular structure is indicated by the arrow in the microscopic image?" "Charcot–Leyden crystal" "Neutrophil granule" "Lymphocyte nuclei" "Russell body" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2577.jpg" -"2578" "Assessing the extracellular matrix surrounding the cellular clusters in the image, what is its primary staining characteristic?" "Basophilic" "Eosinophilic" "Neutrophilic" "Amphophilic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2578.jpg" -"2579" "Based on the visible characteristics of the cells surrounding the duct with an eosinophilic material in its lumen, what cellular feature is prominent in the inflammatory infiltrate?" "Cells with a high nucleus-to-cytoplasm ratio" "Multinucleated giant cells" "Neutrophils with multi-lobed nuclei" "Cells with a low nucleus-to-cytoplasm ratio" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2579.jpg" -"2580" "Based on the nuclear characteristics observed in the cells, what can be inferred about the cellular morphology?" "Nuclei exhibit hyperchromasia with variations in shape and size." "There is a homogenous, relatively low nuclear-to-cytoplasmic ratio." "The nuclei show uniformity and regularity in shape and size." "Cells display a monomorphic appearance with organized alignment." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2580.jpg" -"2581" "What morphological characteristic differentiates the densely packed cells from the more sparse cellularity in this tissue sample?" "The density of the cytoplasm" "The shape of the cells" "The prominence of nucleoli" "The pattern of staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2581.jpg" -"2582" "Which feature in the image is most consistent with the type A component of a thymoma?" "Dark staining areas with a prominent membranous pattern" "Densely packed cells with prominent nucleoli" "Sparse cellularity with lightly stained regions" "Cells exhibiting high degrees of pleomorphism" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2582.jpg" -"2583" "What is the predominant chromatin pattern observed in the nuclei of these cells?" "Smudgy chromatin" "Vesicular chromatin" "Salt-and-pepper chromatin" "Clock-face chromatin" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2583.jpg" -"2584" "What is the appearance of the cytoplasm in these cells when stained?" "Eosinophilic and granular" "Eosinophilic and vacuolated" "Basophilic and nongranular" "Amphophilic and vacuolated" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2584.jpg" -"2585" "The morphology of the cells in this image most closely resembles which of the following cell types?" "Plasma cells" "Adipocytes" "Erythrocytes" "Neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2585.jpg" -"2586" "What characteristic feature is observed in the cells pointed out by the black arrow?" "Multinucleated giant cells" "Spindle-shaped cells with a high nuclear to cytoplasmic ratio" "Small, round cells with dense, hyperchromatic nuclei" "Large cells with a signet ring cell appearance due to peripheral cytoplasm" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2586.jpg" -"2587" "Based on the cells marked by the white arrow, which description best fits their appearance?" "Uniform nuclei with abundant cytoplasm" "Hyperchromatic and pleomorphic nuclei within a dense eosinophilic matrix" "Clear cytoplasmic space with peripheral nucleus" "Small size with a high nucleus to cytoplasm ratio" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2587.jpg" -"2588" "Identify the characteristics of the erythroblasts visible in the image." "Cells with multilobed nuclei and dense cytoplasmic granules" "Cells with round to oval nuclei, blue to purple cytoplasm, and open chromatin" "Cells with small, hyperchromatic nuclei and scant cytoplasm" "Cells with large, irregular nuclei, and minimal cytoplasmic staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2588.jpg" -"2589" "What does the high nucleus-to-cytoplasm ratio in the cellular clusters within the image suggest?" "Decreased cellular maturity" "Increased secretion of extracellular matrix components" "Higher lipid content within the cells" "Increased cellular activity or proliferation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2589.jpg" -"2590" "Based on the histological features observed in the image, which cellular adaptation is most likely occurring in the crypt regions of this duodenal tissue?" "Hypertrophy" "Hyperplasia" "Metaplasia" "Atrophy" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2590.jpg" -"2591" "When observing the epithelium covering the villi in this image, what type of infiltrate can be identified that supports the suspicion of a specific gastrointestinal pathology?" "Eosinophilic infiltrate" "Neutrophilic infiltrate" "Granulomatous infiltrate" "Mononuclear infiltrate" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2591.jpg" -"2592" "Based on the tissue morphology, what type of muscle tissue is depicted in the microscopic view?" "Cardiac muscle" "Skeletal muscle" "Smooth muscle" "None of the above" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2592.jpg" -"2593" "What cellular abnormality is present within the myocytes?" "Myofibrillar disarray" "Lipofuscin accumulation" "Increased glycogen deposition" "Cytoplasmic vacuolation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2593.jpg" -"2594" "Based on the arrangement of cells around the glandular structures, what is the most likely histological feature observed in this tissue?" "Multilayering of the epithelial cells" "Pallisading nuclei" "Pleomorphic arrangement" "Disordered hyperchromasia" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2594.jpg" -"2595" "Based on the characteristics of the tumor cells observed in the image, how would you describe the appearance of the chromatin within the nuclei?" "Showing multiple nucleoli within each nucleus" "Fine and evenly distributed" "Coarse and clumped" "Hyperchromatic with clear halos" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2595.jpg" -"2596" "Based on the indicated cells within the tissue section, what cytoplasmic feature is predominant?" "High granularity." "Vesicular structures." "Low granularity." "Lipid droplets." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2596.jpg" -"2597" "Based on nuclear morphology, what is the most appropriate description of chromatin appearance in the depicted cells?" "Vesicular with prominent nucleoli" "Open chromatin with multiple nucleoli" "Clumped with marginated distribution" "Dense with inconspicuous nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2597.jpg" -"2598" "Based on the histological features presented, what is the likely origin of the tissue?" "Epithelial" "Hematopoietic" "Neural" "Mesenchymal" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2598.jpg" -"2599" "What feature characterizes the cells surrounding the central cavity of the hair follicles (HF) observed in the image?" "Elongated, canal-like structures with a narrow lumen" "An inner layer of epithelial cells that are eosinophilic" "Denser, fibrous matrix consistent with the dermis" "Pale-staining centers with a dense, basophilic cell layer" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2599.jpg" -"2600" "In the image, what staining quality is observed in the peripherally located cell layer of the sebaceous glandular lobules (SG)?" "Basophilic with bluish hue" "Eosinophilic with pink to red staining" "Hematoxyphilic with purple staining" "Lipophilic with clear staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2600.jpg" -"2601" "The eosinophilic, acellular material observed in the lower left of the image suggests it could be:" "An area of fibrosis" "Necrotic tumor tissue" "Normal adipose tissue" "An embolic material" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2601.jpg" -"2602" "What does the increased presence of blood vessels in the tissue sample suggest?" "Acute inflammatory response" "Chronic inflammatory infiltrate" "Normal tissue homeostasis" "Necrotic tissue" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2602.jpg" -"2603" "Based on the morphology of the nuclei visible in the image, what type of cells are most likely forming the clusters?" "Neurons" "Keratinocytes" "Erythrocytes" "Microglia" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2603.jpg" -"2604" "What can be inferred about the pathological state of the tissue based on the image?" "There is evidence of acute inflammation" "Neoplastic transformation is evident" "There are no visible viral inclusion bodies" "Viral inclusion bodies are readily visible" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2604.jpg" -"2605" "Assessing the overall tissue architecture, what change is visible in the dermis as suggested by the presence of the round to oval-shaped structures?" "An expansive process disrupting the dermal architecture." "Formation of granulomas." "Increased vascular proliferation." "Hyaline degeneration." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2605.jpg" -"2606" "What best describes the morphology of the cells indicated by the black arrow?" "Spindle-shaped cells with elongated nuclei" "Round cells with small, hyperchromatic nuclei" "Epithelioid cells with abundant eosinophilic cytoplasm" "Polygonal cells with extensive cytoplasmic processes" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2606.jpg" -"2607" "What cellular elements can be identified within the tubular structures indicated by the black arrows?" "Platelets" "Neutrophils" "Red blood cells" "Epithelial cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2607.jpg" -"2608" "Based on the histological features observed, which of the following conditions is most likely represented in this tissue section?" "Acute tubular necrosis" "Acute cystitis" "Glomerular filtration barrier breakdown" "Polycystic kidney disease" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2608.jpg" -"2609" "What is the likely appearance of the interstitium among the tubules in this H&E stained section of kidney tissue?" "Increased cellularity with possible inflammatory infiltrate" "Clear spaces consistent with edema" "Absence of cells, displaying large open spaces" "Sparse cellularity with mainly fibrous tissue" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2609.jpg" -"2610" "Based on the morphology of the ovoid structures on the right side of the image, what is the most likely diagnosis?" "Adipose tissue" "Normal thyroid follicles" "Muscle fibers" "Parasitic infection" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2610.jpg" -"2611" "What does the dense accumulation of darkly stained cells adjacent to the cyst suggest?" "Hyperplastic growth" "Acute inflammation" "Necrosis" "Chronic inflammation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2611.jpg" -"2612" "What can be inferred about the nuclei of the cells in the dermal layer as seen in the image?" "Nuclei vary in size and shape, suggesting atypical activity" "The presence of large, prominent nuclei is consistent throughout" "There is uniformity in the size and shape of nuclei" "Nuclei are inconspicuous and not easily discernible" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2612.jpg" -"2613" "Are there multinucleated giant cells present in the granulomatous structure?" "It's indeterminate whether multinucleated giant cells are present" "Yes, but multinucleated giant cells are sparse" "Yes, numerous multinucleated giant cells are evident" "No, multinucleated giant cells are not present" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2613.jpg" -"2614" "Is there any evidence of necrosis within the granulomas?" "Yes, but only focal necrosis is seen" "It's unclear if necrosis is present" "No, there is no evidence of necrosis" "Yes, extensive necrosis is visible" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2614.jpg" -"2615" "What is the arrangement of nuclei within the multinucleated giant cells visible in this image?" "Nuclei show a random pattern with no specific arrangement." "Nuclei are clustered in the center of the cytoplasm." "Nuclei are dispersed throughout the cytoplasm." "Nuclei are arranged at the periphery creating a horseshoe-like pattern." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2615.jpg" -"2616" "What does the overall cellular architecture of the tissue indicate?" "The tissue has a systematic, repeating pattern of cells and matrix." "The tissue has a well-organized, layered arrangement." "The tissue is densely packed with cells in a grid-like structure." "The tissue has a loose, disorganized structure without clear layering." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2616.jpg" -"2617" "Examine the underlying connective tissue as shown in this image. What evidence of pathology is observed?" "Fibrosis" "Hemorrhage" "Atrophy of the connective tissue" "Calcification" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2617.jpg" -"2618" "Based on the staining characteristics, what could be inferred about the substance that is staining pink to red in these cells?" "Lipid droplets" "Specific protein or cellular marker" "Extracellular matrix" "Nucleic acids" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2618.jpg" -"2619" "What does the central acellular area demarcated by the wavy white line in the image most closely resemble?" "Granulation tissue" "Mucinous degeneration" "Granuloma" "Necrotic tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2619.jpg" -"2620" "Based on the tissue appearance, which staining technique is likely to have been used for this specimen?" "Hematoxylin and eosin (H&E)" "Periodic acid–Schiff (PAS)" "Immunohistochemistry utilizing horseradish peroxidase (HRP) conjugated secondary antibody" "Masson's trichrome" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2620.jpg" -"2621" "What is the eosinophilic component evident in the histological section of this image?" "Collagenous stroma" "Fibrillary matrix" "Hemorrhagic areas" "Mucinous deposition" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2621.jpg" -"2622" "Based on the immunohistochemical staining observed, which cellular component is most likely being targeted?" "Nuclear proteins" "Cytoplasmic proteins" "Membrane proteins" "Mitochondrial proteins" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2622.jpg" -"2623" "What type of epithelial tissue does this micrograph most likely depict?" "Simple columnar epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2623.jpg" -"2624" "How would you describe the arrangement of myocytes as observed in the image?" "Radially arranged around a central arteriole" "Circular arrangement around a central vein" "Atypical distribution with loss of parallel alignment" "Regular parallel alignment" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2624.jpg" -"2625" "Based on the glandular structures visible in the image, how would you categorize the phase of the endometrial tissue?" "Secretory phase with abundant stroma and decidualization" "Menstrual phase with extensive tissue breakdown and hemorrhage" "Inactive phase with non-proliferative epithelial cells and dense stroma" "Proliferative phase with columnar epithelium and mitotic figures" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2625.jpg" -"2626" "Based on the microscopic image provided, how would you describe the extracellular matrix surrounding the cells?" "Heavily pigmented" "Dense and fibrous" "Lightly stained and homogeneous" "Disorganized with heavy calcification" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2626.jpg" -"2627" "What is the characteristic feature of the larger cells identified in this H&E stained tissue section?" "Clear, vacuolated cytoplasm with dark pyknotic nuclei" "Hyperchromatic nuclei with irregular contours" "Cytoplasmic inclusions resembling viral particles" "Abundant eosinophilic cytoplasm with vesicular nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2627.jpg" -"2628" "What type of mononuclear cells can be seen scattered throughout the stroma in this tissue section?" "Fibroblasts with elongated nuclei" "Inflammatory cells with darker blue nuclei" "Myocytes with striated cytoplasm" "Adipocytes with large lipid vacuoles" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2628.jpg" -"2629" "What is the predominant characteristic of the alveolar exudate observed in the image?" "Eosinophilic, foamy appearance" "Lymphocytic infiltration" "Fibrin deposition" "Neutrophilic infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2629.jpg" -"2630" "What is the predominant staining pattern observed in the connective tissue fibers?" "Intense green fluorescent tagging of fibers" "Dark purple to black nuclear staining" "A consistent pinkish-red coloration throughout" "Brownish-orange coloration specific to certain fibers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2630.jpg" -"2631" "Based on the staining pattern, which intermediate filament protein is most likely being highlighted in the cells within the red circle?" "Glial fibrillary acidic protein (GFAP)" "Vimentin" "Cytokeratin-20" "Desmin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2631.jpg" -"2632" "Which morphological feature is most apparent in the nuclei of the cells shown in the image?" "The nuclei are hyperchromatic with condensed chromatin." "The nuclei exhibit multiple prominent nucleoli." "The nuclei are uniformly round and regular in shape." "There is significant pleomorphism with variation in size and shape." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2632.jpg" -"2633" "What type of staining distribution is most consistently observed across the cells in the image?" "Cytoplasmic staining" "Perinuclear staining" "Nuclear staining" "Membranous staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2633.jpg" -"2634" "What is the characteristic staining pattern of the inclusion bodies seen within the hepatocytes?" "Bright red staining" "Blue-purple staining" "Pale yellow staining" "Bright green fluorescence" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2634.jpg" -"2635" "What is the predominant feature of the large cells with abundant cytoplasm and multiple nuclei in this bone marrow section?" "Cross-striations within the cytoplasm" "Irregularly shaped nuclei" "Conspicuous nucleoli within the nuclei" "Single, round central nucleus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2635.jpg" -"2636" "Based on the pattern of red staining, which histological staining technique is most likely represented in the left side of the image?" "Periodic acid-Schiff (PAS) staining" "Immunohistochemical staining for a specific protein" "Hematoxylin and eosin (H&E) staining" "Toluidine blue staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2636.jpg" -"2637" "What is the characteristic feature of the large cell observed in the center of the image?" "Single, central nucleus" "Single, eccentric nucleus" "Multiple nuclei arranged at the periphery" "Multiple, randomly distributed nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2637.jpg" -"2638" "Based on the tissue architecture observed, which pattern best describes the arrangement of the spindle cells?" "Spindle cells arranged in a haphazard pattern without specific orientation" "Spindle cells arranged in fascicles with a storiform pattern" "Spindle cells forming gland-like structures with lumens" "Spindle cells creating slit-like spaces that may contain red blood cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2638.jpg" -"2639" "In reference to the image, what can be inferred about the brown-staining cells scattered above the basal layer?" "They suggest a benign proliferation of basal cells" "They represent a normal distribution of melanocytes" "They may indicate a pathological invasion of cells into the upper layers" "They are indicative of a typical inflammatory response" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2639.jpg" -"2640" "What is the morphology of the nuclei observed within the cells embedded in the osteoid material?" "Large, vesicular nuclei with prominent nucleoli" "Small, hypochromatic, and monomorphic nuclei" "Large, hyperchromatic, and pleomorphic nuclei" "Uniform, small, round nuclei with abundant cytoplasm" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2640.jpg" -"2641" "Upon examining the osteoid material, how would you describe the pattern of its appearance?" "Fibrous with regular collagen alignment" "Well-organized with a lamellar pattern" "Amorphous and unorganized" "Eosinophilic with uniform calcification" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2641.jpg" -"2642" "Based on the morphology of the central cell, what does the nucleus suggest about the cell's identity?" "Eosinophil with bilobed nucleus" "Neutrophil with segmented nucleus" "Basophil with irregularly lobulated nucleus" "Lymphocyte with large, singular nucleus" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2642.jpg" -"2643" "Based on the glandular structures observed, which feature suggests active inflammation within the tissue?" "Uniform alignment of crypts" "Collections of inflammatory cells within the crypt lumens" "Significant presence of neutrophils within the lamina propria" "Presence of goblet cells in the crypt lining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2643.jpg" -"2644" "In the image of adipose tissue, what does the area with altered dense pink staining likely indicate?" "Normal variation in adipocyte size" "Area of tissue degeneration" "Thickened extracellular matrix" "An influx of inflammatory cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2644.jpg" -"2645" "What histological feature best characterizes the large cells present throughout the image?" "Abundant eosinophilic cytoplasm" "Hyperchromatic nuclei" "Thin cytoplasmic rims and central nucleus" "Multinucleated giant cells" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2645.jpg" -"2646" "Based on the image, which vascular structure is most commonly observed within the tissue?" "Vessels with irregular luminal surfaces lined by endothelial cells" "Elongated vessels with a single layer of endothelial cells" "Circular vessels with multiple layers of smooth muscle cells" "Capillaries with an absent or inconspicuous basal lamina" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2646.jpg" -"2647" "What describes the structural organization of the tissue seen in this image?" "Somewhat organized without clear glandular formation" "Disorganized with glandular formation" "Highly disorganized with irregular cell distribution" "Organized with clear glandular formation" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2647.jpg" -"2648" "How would you describe the stroma surrounding the blood vessels in this image?" "Densely cellular stroma without apparent luminal structures" "Loose stroma with myxoid changes" "Fibrotic stroma with extensive collagen deposition" "Adipose stroma with clear vacuoles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2648.jpg" -"2649" "Based on the morphological features observed, which pattern of melanocyte arrangement is noted in this skin section?" "Solely forming large dermal nests" "Organized in a lentiginous pattern" "Uniformly spread along the dermo-epidermal junction" "Randomly dispersed throughout the epidermis" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2649.jpg" -"2650" "Based on the cellular morphology, what is the condition of the hepatocytes in this image?" "Inflammation" "Steatosis" "Necrosis" "Normal" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2650.jpg" -"2651" "What is the predominant cell shape observed in this histopathological image?" "Cuboidal" "Round" "Polygonal" "Spindle-shaped" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2651.jpg" -"2652" "Based on the immunohistochemical staining pattern observed, which statement about the cytoplasmic expression is accurate?" "The cytoplasm does not appear to be stained" "The cytoplasm shows patchy and inconsistent staining" "The cytoplasm exhibits diffuse and prominent staining" "The cytoplasmic staining is concentrated around the nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2652.jpg" -"2653" "Analyzing the nuclear features, how can the appearance and dispersion of chromatin within the nuclei primarily be characterized?" "The nuclei display multiple nucleoli and thick chromatin threads" "The chromatin in the nuclei is heavily condensed and fragmented" "The chromatin appears clumped with prominent nucleoli" "The nuclei show fine chromatin without obvious nucleoli" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2653.jpg" -"2654" "Which layer in this tissue section is identified by the presence of more densely packed and larger cells with prominent nuclei?" "Photoreceptor layer (PRL)" "Ganglion cell layer (GCL)" "Inner plexiform layer (IPL)" "Outer nuclear layer (ONL)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2654.jpg" -"2655" "What is the characteristic feature of the brownish structures found in the ganglion cell layer (GCL)?" "Immunohistochemical staining indicating targeted protein accumulation" "Lipofuscin granules indicating cellular aging" "Corpora amylacea indicating aging or degenerative process" "Myelin figures indicating degeneration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2655.jpg" -"2656" "What is the predominant staining pattern observed in the cells?" "Strong membranous staining" "Perinuclear halo staining" "Uniform cytoplasmic staining" "Diffuse nuclear staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2656.jpg" -"2657" "Assessing the morphological features, which description best fits the observed cellular architecture?" "Pleomorphic without glandular structures" "Spindle-shaped with organized alignment" "Cuboidal with dense stromal arrangement" "Uniform with glandular structures" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2657.jpg" -"2658" "Based on the cellular characteristics and tissue architecture in the image, which finding is most consistent with this microscopic view?" "Normal tissue organization" "Neoplastic tissue" "Low cellular proliferation" "Well-differentiated cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2658.jpg" -"2659" "Based on the cell morphology, what is the most likely nature of the cells represented by the brown-stained cluster?" "The cells represent a high-grade dysplastic change." "The cell morphology suggests an undifferentiated cell type." "The cells are consistent with a benign immunoprofile." "The cells show characteristics of malignant transformation." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2659.jpg" -"2660" "Assessing the tissue organization, what is the most discernible structural characteristic?" "Densely packed cells in certain areas" "Homogeneous cell distribution throughout the tissue" "A single layer of uniform cells" "Clear glandular structures with defined lumina" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2660.jpg" -"2661" "Based on the immunohistochemical staining and cellular morphology, what is the most likely function of the brown-stained protein?" "Hemoglobin transport" "Intercellular adhesion" "Enzymatic activity" "Hormone secretion" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2661.jpg" -"2662" "Considering the blue-stained areas of the cells, what does the appearance of the nuclei suggest about the tissue's condition?" "Possible malignancy" "Senescence" "Cellular quiescence" "Active DNA replication" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2662.jpg" -"2663" "Based on the staining properties, how would you describe the sarcoplasm of the muscle fibers seen in the image?" "Amphophilic" "Lightly eosinophilic" "Basophilic" "Deeply eosinophilic" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2663.jpg" -"2664" "What staining technique is likely used in this microscopic image based on the coloration and visibility of cellular features?" "Acid-fast stain" "Hematoxylin and Eosin (H&E) stain" "Periodic acid-Schiff (PAS) stain" "Wright-Giemsa stain" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2664.jpg" -"2665" "Based on the cellular morphology visible in this image, which type of white blood cell is prominently featured due to its large nucleus relative to its cytoplasm?" "Monocytes" "Lymphocytes" "Basophils" "Neutrophils" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2665.jpg" -"2666" "Identify the specific type of white blood cell that is characterized in the image by showing bilobed nuclei and granular cytoplasm." "Neutrophils" "Basophils" "Lymphocytes" "Eosinophils" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2666.jpg" -"2667" "What feature distinguishes the smaller cells surrounding the larger cells in this image?" "High nuclear-to-cytoplasm ratio" "Significant granulation" "Prominent nucleoli" "No visible nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2667.jpg" -"2668" "Assessing the cellular morphology, what characteristic is predominant in the cells displayed in the image?" "Variable nuclear size with prominent nucleoli" "Abundant granular eosinophilic cytoplasm" "Spindle-shaped cells with elongated nuclei" "Multinucleated giant cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2668.jpg" -"2669" "Regarding the chromatin distribution within the nuclei of the cells observed, what is the most accurate description?" "Clearing around the nucleoli" "Heterogeneously stained" "Margination along the nuclear membrane" "Uniform chromatin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2669.jpg" -"2670" "Assessing the stromal component in the image, which feature is most prominently observed?" "Edematous stroma with extensive hemorrhage" "Myxoid stroma with scattered inflammatory cells" "Highly cellular stroma with numerous mitotic figures" "Fibrous stroma with loose connective tissue" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2670.jpg" -"2671" "Based on the image, how would you characterize the nucleus-to-cytoplasm (N:C) ratio within these cells?" "High N:C ratio with nuclei occupying most of the cellular volume" "Normal N:C ratio consistent with healthy tissue" "Extremely low N:C ratio indicative of cytoplasmic swelling" "Low N:C ratio with abundant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2671.jpg" -"2672" "Considering the structure and distribution, which adnexal structures are likely present within the dermis?" "Apocrine sweat glands" "Hair follicles" "Eccrine sweat glands" "Sebaceous glands" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2672.jpg" -"2673" "Based on the cellular morphology observed in the histological section, what is the predominant shape of the tumor cells?" "Cuboidal" "Polygonal" "Spindle-shaped" "Round" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2673.jpg" -"2674" "Considering the appearance of the cytoplasm in the image, how would you characterize its staining properties?" "Basophilic" "Eosinophilic" "Amphophilic" "Clear" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2674.jpg" -"2675" "Based on the presence of large blue intracytoplasmic inclusions within the cells in the image, what is the most likely composition of these inclusions?" "Mucin" "Glycogen" "Hemoglobin" "Lipofuscin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2675.jpg" -"2676" "Where is the immunohistochemical marker most prominently localized in this tissue sample?" "Throughout the extracellular matrix" "On the apical surface of the epithelial layer" "Within the nuclei of the epithelial cells" "Along the basement membrane" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2676.jpg" -"2677" "Based on the staining pattern, what is the likely function of the cells that have been targeted by MoAb BG1?" "Secretion due to intense cytoplasmic staining" "Motility or sensory due to ciliary expression" "Absorption due to microvilli presence" "Inter-cell connection due to tight junction presence" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2677.jpg" -"2678" "Within the germinal center, how do the centroblasts and centrocytes appear in comparison to the surrounding mantle zone lymphocytes?" "They contain more cytoplasmic granules and larger nuclei" "They have darker-staining nuclei with a denser appearance" "They exhibit less dense chromatin giving a lighter appearance" "They have paler cytoplasm and slightly irregular nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2678.jpg" -"2679" "What characteristic feature is evident in the blood vessels visible within the germinal center?" "Prominently thickened or hyalinized appearance" "Regular anatomic structure with typical thin vessel walls" "Clear definition with a well-formed lumen and endothelial lining" "Inflammation with adjacent leukocyte infiltration" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2679.jpg" -"2680" "What morphology does the peripheral zone (mantle zone) surrounding the germinal center exhibit?" "Irregular structure with mixed cell types" "Darker-staining with densely packed lymphocytes" "Predominantly pink-staining with scattered lymphocytes" "Lighter staining than the germinal center with sparsely packed cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2680.jpg" -"2681" "Considering the stromal component seen in the image, which description accurately characterizes it?" "Abundant eosinophilic stroma encasing uniformly shaped glands" "Hypocellular stroma with abundant extracellular matrix" "Fibrotic stroma with significant inflammatory infiltrate" "Minimal pink-staining stroma interspersed between cellular regions" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2681.jpg" -"2682" "Based on the microphotograph, what best describes the cellularity of the glomerulus?" "Normocellular" "Hypercellularity" "Oligocellular" "Atrophic cellularity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2682.jpg" -"2683" "What is the organization of the surrounding tissue relative to the area with the arrows?" "Well-organized epithelial structure with some variability" "Less organized with varying cell sizes and nuclear spacing" "Completely disorganized with numerous mitotic figures" "Predominantly hyperplastic with significant pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2683.jpg" -"2684" "Which cells in the image are identified as plasma cells based on their morphology?" "Large cells with an irregular nucleus and abundant cytoplasm" "Cells with eccentrically placed nuclei and an off-center cartwheel chromatin pattern" "Cells with large, pale nuclei and foamy cytoplasm" "Small cells with a high nuclear to cytoplasmic ratio and dense chromatin" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2684.jpg" -"2685" "Based on the tissue morphology, how would you describe the condition of the alveolar walls adjacent to the eosinophilic material?" "Infiltrated with inflammatory cells" "Thin and lined with flattened cells" "Lined with hyperplastic pneumocytes" "Thickened and fibrotic" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2685.jpg" -"2686" "What morphological feature is characteristic of the cells observed in this high magnification H&E stained microscopic image?" "Nuclear displacement to the periphery with intracellular mucin" "Multinucleation with a syncytial arrangement" "Abundant eosinophilic cytoplasm without nuclear atypia" "Formation of glandular structures with central necrosis" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2686.jpg" -"2687" "What cellular morphology is primarily visible among the neoplastic cells in this image of papillary carcinoma?" "Pleomorphic cells with variable nuclei sizes" "Spindle-shaped cells with dense eosinophilic cytoplasm" "Uniform, small cells with high nuclear-to-cytoplasmic ratio" "Small, round cells with scant cytoplasm" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2687.jpg" -"2688" "In the provided image, what type of pigmented material is most likely present within the stroma?" "Lipofuscin" "Bilirubin" "Hemosiderin" "Melanin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2688.jpg" -"2689" "Considering the composition of the intercellular matrix seen in the image, what is its most likely primary component?" "Collagenous connective tissue" "Adipose tissue" "Hyaline cartilage" "Mucinous stroma" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2689.jpg" -"2690" "Assessing the pattern of chromatin within the nuclei, what is the most accurate observation from this image?" "Nuclei with irregular chromatin pattern and visible nucleoli" "Regularly arranged chromatin with well-defined nuclear margins" "Hyperchromatic nuclei with uniformly dispersed chromatin" "Nuclei without visible nucleoli" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2690.jpg" -"2691" "What is the most notable feature of the glomerular capillary loops in this renal tissue sample?" "Lack of staining" "Sclerosis" "Thickening of the basement membrane" "Hypercellularity" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2691.jpg" -"2692" "Considering the eosinophilic cytoplasm and the density of the cell population in this section, what is the most likely histopathological assessment?" "The tissue demonstrates lipomatous differentiation with abundant pink cytoplasm." "The tissue suggests an inflammatory infiltrate, rich in eosinophils." "The tissue shows acellular eosinophilic deposits, typical of amyloidosis." "The tissue exhibits hypercellularity with sparse eosinophilic cytoplasm, indicative of a high-grade malignancy." "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2692.jpg" -"2693" "Based on the nuclei's appearance, what can be inferred about the cells observed in this microscopic image?" "The cells' nuclei reveal pleomorphism." "The cells show characteristics of atypia." "The cells exhibit uniform nuclei, suggesting normalcy." "The cells are likely undergoing rapid mitosis." "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2693.jpg" -"2694" "Identify the likely primary function of this tissue based on cellular morphology and arrangement." "Filtration and reabsorption with evidence of abundant interstitial space" "Secretion of hormones due to dense core of cells" "Protection from physical wear with multiple cell layers" "Conduction of electrical impulses because of elongated cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2694.jpg" -"2695" "What specific structural feature can be observed surrounding the cellular clusters, and what is its likely function?" "Erythrocytes aggregation suggesting inflammatory response" "Multiple cell layers for protective lining" "Loose connective tissue indicative of a supportive stroma" "Thick hyalinized bands suggesting a restrictive tissue barrier" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2695.jpg" -"2696" "What is the predominant cell shape visible in this microscopic image of the tissue?" "Squamous (flat and scale-like)" "Spindle-shaped (elongated with pointed ends)" "Columnar (taller than they are wide)" "Cuboidal (cube-like)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2696.jpg" -"2697" "How are the nuclei of the cells predominantly arranged in the tissue examined?" "Small and inconspicuous" "Hyperchromatic and clustered" "Elongated and wavy" "Round and uniform" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2697.jpg" -"2698" "What pattern of tissue structure can be identified in this microscopic image?" "Disorganized, anarchic structure" "Rosette formation" "Interlocking fascicular pattern" "Glandular arrangement" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2698.jpg" -"2699" "Considering the structures observed under polarized light, what could be a possible composition of the birefringent deposits?" "Cholesterol crystals" "Amyloid deposition" "Calcium oxalate crystals" "Fibrin deposits" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2699.jpg" -"2700" "What is the most notable nuclear characteristic of the follicular epithelial cells in this thyroid tissue section?" "Uniform small nuclei" "Nuclear molding" "Nuclear pleomorphism" "Multinucleation" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2700.jpg" -"2701" "In assessing the degree of hyperactivity or neoplastic change, which feature of the follicles here is particularly indicative?" "Presence of microfollicular structures" "Increased follicular cell layering" "Presence of abundant colloid" "Absence of colloid in follicular lumen" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2701.jpg" -"2702" "Considering the presence and localization of immunohistochemical staining, which conclusion can be drawn?" "The nuclear localization of the protein expression indicates a vascular neoplasm." "Positive staining in the nuclei suggests a neoplasm of hematopoietic origin." "The absence of nuclear staining signifies a benign lesion of mesenchymal origin." "The cells are most likely of epithelial origin due to cytoplasmic staining." "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2702.jpg" -"2703" "How would you characterize the cytoplasm of the trophoblastic cells lining the villi?" "Homogeneous with abundant granular cytoplasm" "Homogeneous with scanty cytoplasm" "Granular and foamy with multiple vacuoles" "Homogeneous with abundant vacuolated cytoplasm" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2703.jpg" -"2704" "What is the overall pattern of the tissue's architecture based on the visible cellular organization in the image?" "The cells are arranged in a whorled pattern." "The cells exhibit uniformity and lack of obvious structural disorganization." "The cells are organized in a glandular pattern." "The cells are organized in a dysplastic pattern." "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2704.jpg" -"2705" "Based on the nuclear features, which of the following best characterizes the cellular changes observed?" "Uniform nuclear shapes with consistent staining intensity" "Mild nuclear pleomorphism with hyperchromasia" "Marked nuclear pleomorphism with prominent nucleoli" "Smudged nuclear chromatin with karyorrhectic debris" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2705.jpg" -"2706" "Assessing the tissue features presented, which finding is NOT observed in this image?" "Cells with spindle-shaped nuclei" "Eosinophilic cytoplasm in the spindle cells" "Presence of multinucleated giant cells" "Organized spindle cells with a mesenchymal pattern" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2706.jpg" -"2707" "Which feature is prominent in the nuclei of the atypical plasma cells indicated by the arrows?" "Prominent nucleoli" "Hypersegmented nuclei" "Clock-face chromatin pattern" "Multilobed nuclei" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2707.jpg" -"2708" "Based on the microscopic image, how would you characterize the population of neutrophilic leukocytes present?" "Presence of band forms and less mature neutrophils" "Predominance of myeloblasts" "Presence of hypersegmented neutrophils" "Predominance of segmented neutrophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2708.jpg" -"2709" "What does the predominant pink to eosinophilic staining material distributed within this tissue sample most likely represent?" "Skeletal muscle fibers" "Collagen bundles" "Areas of necrosis or fibrin deposition" "Mucinous carcinoma" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2709.jpg" -"2710" "What can be inferred from the organized clusters of cells with darker staining nuclei within this tissue sample?" "Normal lymphoid follicles" "Granuloma formation" "Adipose tissue" "Neoplastic cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2710.jpg" -"2711" "What is the primary characteristic of the lesion's central material?" "Eosinophilic collagen deposition" "Necrotic debris with inflammatory infiltrate" "Keratinous acellular material" "Mucinous extracellular substance" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2711.jpg" -"2712" "How does the intensity of the brown cytoplasmic staining vary between the upper and lower layers of the stratified squamous epithelium?" "The intensity is greater in the upper layers than in the lower layers" "The intensity is uniform throughout the tissue" "There is no brown cytoplasmic staining present in the tissue" "The intensity is greater in the lower layers than in the upper layers" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2712.jpg" -"2713" "What is the nuclear morphology of the cells found in the upper layers of the epithelium?" "The nuclei are small and irregularly shaped" "The nuclei are not visible in the upper layers" "The nuclei are large and round with uniform spacing" "The nuclei are large and clustered together" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2713.jpg" -"2714" "Based on the arrangement and morphology of the cells, how would you characterize the tissue structure?" "Crowded with a lack of clear organizational structure" "Neoplastic transformation with high-grade features" "Well-differentiated with tubular formation" "Regular and homogenous with clear boundaries" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2714.jpg" -"2715" "What can be inferred about the nuclei of the darkly stained cells in the image?" "They are hypertrophic, suggesting a hyperplastic process" "They exhibit rounded to irregular shapes, typical of lymphocytes" "They are swollen with clear nucleoli, signifying cell injury" "They are uniform and regular, indicative of healthy cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2715.jpg" -"2716" "Based on the microscopic characteristics observed, what is the histologic feature indicated by the thickened outer layer of the epidermis?" "Parakeratosis" "Spongiosis" "Acanthosis" "Hyperkeratosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2716.jpg" -"2717" "In the dermis, a structure is accompanied by surrounding connective tissue with a dense infiltrate of cells. What is this structure most likely to be?" "Hair follicle" "Sebaceous gland" "Eccrine sweat gland" "Melanocytic nevus" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2717.jpg" -"2718" "What does the counterstain color in the non-neoplastic cell nuclei suggest about the non-neoplastic population's expression of the target antigen in this image?" "It suggests high levels of target antigen expression" "It indicates no expression of the target antigen" "It indicates uniform expression of the target antigen across all cells" "It suggests varied expression of the target antigen" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2718.jpg" -"2719" "How would you describe the overall cellular morphology of the brown-stained cells based on your observations of the image?" "The cells are pleomorphic with irregular nuclei" "The cells have spindle-shaped morphology with clear cytoplasmic boundaries" "The cells are uniform in size and shape with obscured nuclei" "The cells exhibit significant anisokaryosis with multiple nucleoli" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2719.jpg" -"2720" "What particular antigen is most likely being highlighted by the brown coloration in the endothelial cells?" "Ulex europaeus agglutinin I" "CD31" "CD34" "Factor VIII" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2720.jpg" -"2721" "Based on the morphology and staining pattern, what feature distinguishes the endothelial cells from the suspected tumor cells?" "Less variability in cell size and shape" "All of the above" "A more structured distribution" "The presence of a visible lumen" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2721.jpg" -"2722" "Based on the morphology of the epithelium observed in the image, what cellular changes can be inferred?" "Hyperplasia of the basal layer" "Complete metaplasia of the epithelial layer" "Hypertrophy of the squamous cells" "Dysplasia of the surface epithelium" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2722.jpg" -"2723" "What does the appearance of the stroma beneath the epithelium in the image likely indicate?" "The presence of substantial fibrosis and chronic scarring" "Indications of loose, edematous connective tissue with sparse inflammatory cells" "Signs of granulomatous inflammation" "Evidence of acute hemorrhagic activity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2723.jpg" -"2724" "Regarding the renal tubules in this image, which statement best describes their interaction with the immunohistochemical stain?" "The tubules are mostly unstained" "Only the luminal surface of the tubules is stained" "The tubules show a high degree of staining throughout their structure" "The tubules exhibit primarily nuclear staining" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2724.jpg" -"2725" "What is the predominant localization pattern of the immunostaining in the majority of the brown-stained cells seen in the image?" "Extracellular" "Nuclear" "Membranous" "Cytoplasmic" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2725.jpg" -"2726" "Based on the staining intensity and distribution in the image, how would you describe the expression pattern of the antigen in the tissue section?" "Heterogeneous and dispersed" "Homogeneous and dispersed" "Homogeneous and clustered" "Heterogeneous and clustered" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2726.jpg" -"2727" "What cellular morphology is suggested by the size and nucleus-to-cytoplasm ratio of the brown-stained cells in this image?" "Neurons" "Epithelial cells" "Lymphocytes" "Hepatocytes" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2727.jpg" -"2728" "What does the lightly stained cytoplasm of the neurons within the granular layer (area labeled '2') suggest about the content of the cytoplasm?" "Accumulation of neuropathological inclusions" "Low density of organelles" "Abundance of neurofibrillary tangles" "High concentration of Nissl substance" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2728.jpg" -"2729" "What is the most appropriate diagnosis based on the appearance of the epithelial layer in the image?" "Acantholysis" "Spongiosis" "Acanthosis" "Hyperkeratosis" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2729.jpg" -"2730" "Based on the histological appearance, how would you describe the distribution of chondrocytes within the cartilaginous tissue seen in the image?" "Clumped together in isogenous groups" "Randomly distributed without lacunae" "Densely packed within lacunae" "Sparsely distributed within lacunae" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2730.jpg" -"2731" "What type of background matrix is visible in this microscopic image?" "Dense connective tissue" "Hyaline cartilage" "Pale eosinophilic matrix with fat vacuoles" "Lymphoid tissue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2731.jpg" -"2732" "By examining the eosinophilic cytoplasm of the cells on the left side of the image, how would you describe the granularity of the cytoplasm?" "Coarse and clumped" "Signet ring-like vacuolization" "Fine and evenly distributed" "Abundant with lipid droplets" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2732.jpg" -"2733" "In the renal glomeruli observed on the right side of the image, what is the prominent feature visible within the capillary lumens?" "Red blood cells" "Proteinaceous deposits" "Immune cell infiltrates" "Fibrin thrombi" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2733.jpg" -"2734" "Based on the staining pattern in the image, where is the antigen targeted by the immunohistochemical stain most likely localized?" "In the extracellular matrix" "Throughout the cytoplasm of the cells" "Within the nucleus of the cells" "Along the cell membrane" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2734.jpg" -"2735" "How do the nuclei of positively stained cells for estrogen receptors compare in size to the nuclei of unstained cells?" "Positively stained nuclei show a more uniform size compared to unstained nuclei" "Positively stained nuclei are generally smaller than unstained nuclei" "Positively stained nuclei are generally larger than unstained nuclei" "Positively stained nuclei and unstained nuclei are approximately the same size" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2735.jpg" -"2736" "Based on the cytoplasmic characteristics evident in the image, which description is most accurate?" "Pale eosinophilic cytoplasm with prominent vacuolization" "Cytoplasm with dark, brownish staining suggesting the presence of a specific marker" "Homogenous cytoplasmic staining with no visible granularity" "Clear cytoplasm with abundant glycogen" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2736.jpg" -"2737" "What is the morphology of the cells lining the central irregularly-shaped channel?" "Spindle-shaped cells" "Cuboidal epithelial cells" "Columnar epithelial cells" "Squamous epithelial cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2737.jpg" -"2738" "Based on the tissue structures visible, what is a likely function of the tissue section presented?" "Gas exchange" "Immune response or fluid balance" "Nutrient absorption" "Hormone secretion" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2738.jpg" -"2739" "Based on the epithelial cell morphology, which of the following best characterizes the epithelial cells observed in the image?" "Columnar epithelial cells with basal nuclei" "Squamous epithelial cells with abundant cytoplasm" "Basal cells with high nuclear-to-cytoplasmic ratio" "Cuboidal epithelial cells with central nuclei" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2739.jpg" -"2740" "Based on the morphological features observed in the image, what is the likely nature of the pale eosinophilic to amorphous central structure indicated by the arrow?" "Normal adipose tissue" "Necrotic tumor cells" "Degenerated foreign body material" "Skeletal muscle fibers" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2740.jpg" -"2741" "Based on the cross-sectional view of the tissue, what is the characteristic pattern of the muscle fibers observed?" "Parallel arrangement with one centrally located nucleus per cell" "Branching pattern with one centrally located nucleus per cell" "Circular arrangement with peripheral nuclei" "Irregular arrangement with multiple nuclei per cell" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2741.jpg" -"2742" "Upon examining the epithelial tissue section, which feature should be primarily identified to diagnose it as cervical intraepithelial neoplasia 1 (CIN1)?" "Full-thickness epithelial atypia" "Cellular atypia in the upper third of the epithelium" "Abnormal mitotic figures throughout the epithelium" "Cellular atypia in the lower third of the epithelium" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2742.jpg" -"2743" "Based on the staining pattern observed in the image, what is the most likely staining technique used?" "Periodic acid-Schiff (PAS) staining" "Masson's trichrome staining" "Immunoperoxidase staining" "Hematoxylin and eosin (H&E) staining" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2743.jpg" -"2744" "What can be inferred about the nucleus placement of the observed cells in this microscopic image?" "Nuclei are placed at the extreme periphery of the cells" "Nuclei are eccentrically located" "Cells exhibit multinucleation" "Nuclei are centrally located" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2744.jpg" -"2745" "In the context of the extracellular matrix and connective tissues staining, which feature stands confirmed by examining the image?" "Stroma appears green" "Matrix appears blue due to metachromatic staining" "Extracellular matrix possesses pink to red staining" "Connective tissues depict a purple hue" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2745.jpg" -"2746" "Based on the cellular arrangement seen in the follicles, what is a key diagnostic feature of the cells surrounding the central mass?" "Presence of reverse nuclear polarity" "High mitotic index" "Presence of multinucleated giant cells" "Absence of nuclear pleomorphism" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2746.jpg" -"2747" "How would you describe the nuclei of the spindle-shaped cells in the connective tissue stroma?" "The nuclei have a florid granular appearance with large nucleoli" "The nuclei appear small, condensed, and uniform in size" "The nuclei are elongated with evenly distributed chromatin" "The nuclei show severe hyperchromasia and anisokaryosis" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2747.jpg" -"2748" "Examining the cell density around the blood vessel, what type of cellular accumulation is observed?" "Predominantly lymphocytes" "Predominantly macrophages" "Predominantly neutrophils" "Predominantly eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2748.jpg" -"2749" "What feature of adipose tissue is distinctly visible in the region adjacent to the bone marrow in the image?" "Signet ring appearance" "Cross-striations" "Central nucleus" "Multilocular lipid vacuoles" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2749.jpg" -"2750" "Identify the structure that separates the bone marrow from the adipose tissue in the image based on its morphological characteristics." "Elastic fibrous tissue" "Eosinophilic striated muscle fibers" "Bony trabecula" "Collagenous fibrous septa" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2750.jpg" -"2751" "Based on the morphology seen in this histological slide, which tissue characteristic can be determined?" "Presence of cuboidal epithelial cells" "Presence of squamous epithelial cells" "Presence of glandular structures" "Presence of spindle-shaped cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2751.jpg" -"2752" "What does the cellular arrangement in the tissue sample suggest about the potential origin of the lesion?" "Random arrangement suggesting a mesenchymal origin" "Organized pattern suggesting a well-differentiated neoplasm" "Papillary structures suggesting epithelial origin" "Rosette formation suggesting neuroendocrine origin" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2752.jpg" -"2753" "In the provided tissue section stained with hematoxylin and eosin (H&E), what characteristic do the observed red-stained areas most likely represent?" "Areas of necrosis within the tumor" "Blood vessels characterized by red blood cells" "Eosinophilic cytoplasmic staining" "Concentrations of inflammatory cells" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2753.jpg" -"2754" "What can be deduced regarding the tissue architecture from the image?" "Monotonous cellular population" "Well-defined glands with polarized cells" "Disordered growth pattern" "Intact basement membrane" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2754.jpg" -"2755" "The region marked with a triangle most likely represents which of the following, based on the observed histological features?" "Hyaline cartilage as evidenced by glassy, eosinophilic matrix" "Nervous tissue with prominent axons and myelin sheath structures" "Dense, fibrous connective tissue due to the presence of collagen fibers" "Fatty marrow characterized by vacuolated cells with clear cytoplasmic spaces" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2755.jpg" -"2756" "Based on cellular morphology, what is the characteristic feature of the cell indicated by the black arrow?" "Hypersegmented polymorphonuclear leukocyte" "Multiple small vacuoles within the cytoplasm" "A prominent nucleolus within the nucleus" "A large inclusion body within the nucleus" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2756.jpg" -"2757" "In the areas marked by white arrows, what is the most likely identity of the granular-looking structures?" "Bacterial colonies" "Glycogen accumulation" "Keratohyalin granules" "Mitochondrial aggregations" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2757.jpg" -"2758" "What cellular feature is most prominent in the cells infiltrating the surrounding tissue?" "Eosinophilic cytoplasm" "Multi-lobed nuclei" "Binucleated lymphocytes" "Lipid droplets in adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2758.jpg" -"2759" "In the microscopic view of this bone tissue, what is the pattern of the lamellar bone formation?" "Irregular and disorganized" "Random with dispersed osteocytes" "Parallel and unidirectional" "Concentric with a whirlpool-like arrangement" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2759.jpg" -"2760" "The clear, elongated, tubular spaces visible in this image primarily represent what part of the bone's structure?" "Areas of new bone formation" "Fibrovascular channels" "Osteocyte lacunae" "Areas of osteoclastic activity" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2760.jpg" -"2761" "Are there any characteristics in this image that would suggest an inflammatory response?" "Congestion of the interstitial tissue" "Abundant fibrotic tissue throughout the sample" "Overwhelming granuloma formation" "Presence of numerous eosinophils" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2761.jpg" -"2762" "Assessing the mitotic activity within the sample, what observation can be made?" "Uniform distribution of cells in various stages of mitosis" "Increased mitotic activity and presence of atypical mitotic figures" "No mitotic figures are visible" "Cells are predominantly in the resting phase (interphase)" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2762.jpg" -"2763" "What can be inferred about the type of cells based on their morphology in the hematopoietic bone marrow?" "These are atypical lymphoid cells" "They represent mature adipocytes" "There is a predominance of megakaryocytes" "The cells are predominantly erythroblasts" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2763.jpg" -"2764" "In the lower part of the image, marked by the blue arrowhead, what is the characteristic feature observed in the muscle fibers?" "Fibrous tissue deposition" "Central nuclei" "Signs of necrosis" "Distinct bands of striation" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2764.jpg" -"2765" "The muscle fibers adjacent to the area of focal infiltration show which of the following conditions?" "Increase in interstitial connective tissue" "Degeneration and disrupted architecture" "Myofibrillar disarray" "Intact morphology" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2765.jpg" -"2766" "What histopathological feature is NOT easily identified in this field of view but is often found in actively proliferating neoplasms?" "Regular tissue architecture" "Mitotic figures" "Uniform cell size" "Round to oval nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2766.jpg" -"2767" "Analyzing the peripheral blood smear image, what is suggested by the presence of larger cells with folded or indented nuclei amongst the majority of red blood cells?" "Early erythrocyte precursors" "Monocytes with cytoplasmic and nuclear features" "Neutrophil segmentation" "Platelet aggregates" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2767.jpg" -"2768" "Based on the striations and the location of the nuclei in the muscle cells observed in the image, which type of muscle tissue is depicted?" "Non-muscular connective tissue" "Skeletal muscle" "Cardiac muscle" "Smooth muscle" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2768.jpg" -"2769" "What is observed about the cytoplasm of the cells encircled in red compared to their nuclei?" "The abundant cytoplasm is deeply stained, rendering the nuclei inconspicuous" "The cytoplasm is dense and scant, drawing attention to the altered nuclear features" "The cytoplasm is generous with a high cytoplasmic-to-nuclear ratio" "The cytoplasm is abundant and clear, overshadowing the nuclei" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2769.jpg" -"2770" "What is the morphology of the cells within the stromal component of the tissue when evaluating the microscopic image?" "Irregular and loosely connected" "Spindle-shaped and densely packed" "Round and densely arranged" "Spindle-shaped and arranged in a less dense pattern" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2770.jpg" -"2771" "What percentage of cells show a positive reaction with the Ki-67 marker in this image?" "Approximately 50%" "Less than 10%" "Approximately 25%" "More than 75%" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2771.jpg" -"2772" "The eosinophilic (pink-stained) substance in the tissue is most likely composed of:" "Cytoplasmic content from ruptured cells" "Extracellular matrix or fibrin material" "Collagen fibers typically found in connective tissue" "Erythrocytes found within blood vessels" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2772.jpg" -"2773" "What does the presence of areas indicated by double arrows in Image B most likely represent?" "Benign cellular hyperplasia" "Necrosis and lymphocytic infiltration" "Normal tissue regenerative process" "Acute cellular swelling due to hypoxic injury" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2773.jpg" -"2774" "Based on the brown coloration of the elongated, tubular structures, what type of staining method was likely applied to this tissue section?" "Masson's trichrome staining" "Immunohistochemical (IHC) staining" "Periodic acid-Schiff (PAS) staining" "Hematoxylin and eosin (H&E) staining" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2774.jpg" -"2775" "Based on the immunohistochemical staining pattern, what type of cells are predominantly identified in the tissue section?" "Neuronal cells" "Fibroblasts" "Epithelial cells" "Astrocytic cells" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2775.jpg" -"2776" "Based on the staining pattern observed in the image, which intracellular component predominantly exhibits the presence of the targeted antigen?" "Nucleus" "Nucleoli" "Cytoplasm" "Mitochondria" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2776.jpg" -"2777" "Regarding the morphology of the cells observed, what level of pleomorphism can be inferred from the image?" "Severe pleomorphism" "Mild pleomorphism" "Moderate pleomorphism" "No pleomorphism" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2777.jpg" -"2778" "What type of specialized cells, indicative of a particular process, are observed in the upper left portion of the image?" "Lymphocytes with dense chromatin" "Cells with abundant melanocytic granules" "Cells with hemosiderin deposits" "Keratin pearls" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2778.jpg" -"2779" "Which type of abnormal cells are identified by their morphology and visible near the center of the image, suggesting a specific type of neoplastic change?" "Lipoblasts" "Karyorrhectic cells" "Syncytial trophoblasts" "Sternberg-Reed cells" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2779.jpg" -"2780" "Based on the architectural features seen in this microscopic image, which of the following best describes the tissue arrangement?" "Uniform cell distribution with a structured basal layer" "Irregular cell arrangement and disturbed tissue stratification" "Layers of undifferentiated, homogenous cells" "Organized stratification with minimal nuclear variability" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2780.jpg" -"2781" "What is the cytoplasmic appearance of the cells pointed out by the arrow in the image indicative of?" "Basophilic (dark-stained) cytoplasm" "Mucinous cytoplasm" "Clear, vacuolated cytoplasm" "Eosinophilic (pink-stained) cytoplasm with keratinization" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2781.jpg" -"2782" "Based on the micrograph, what is the most likely composition of the internal contents of the central round structure?" "Dense fibrous stroma" "Hyphae with septations" "Group of endospores" "Uniformly distributed chromatin" "C" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2782.jpg" -"2783" "What feature of the central structure in the micrograph is suggestive of a pathogenic fungal element?" "A thick, well-defined wall" "Budding yeast forms" "Presence of branching at acute angles" "Formation of pseudohyphae" "A" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2783.jpg" -"2784" "Which type of cells appear to be most numerous in this hematopoietic tissue sample?" "Cells with dense, compact chromatin and no visible nucleoli" "Cells with abundant cytoplasm and regular nuclei" "Cells with a low nuclear-to-cytoplasmic ratio and segmented nuclei" "Cells with a high nuclear-to-cytoplasmic ratio and irregular nuclei" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2784.jpg" -"2785" "What is the predominant feature identified by the dark brown immunohistochemical staining in this dermal tissue section?" "Collagen bundles" "Lymphocytes" "Epidermal keratinocytes" "Adipocytes" "B" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2785.jpg" -"2786" "What is the most notable feature in the center of the granuloma as observed in the microscopic image of the splenic tissue?" "Suppurative inflammation" "Foreign body giant cells" "Caseating necrosis" "Epithelioid histiocytes" "D" "PubMed" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2786.jpg" -"2787" "Based on the morphology of the structures observed in this tissue section, what type of pathologic process do they most likely represent?" "Benign cystic formations" "Dysplastic tissue changes" "Granulomatous inflammation" "Neoplastic solid tumoral growth" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2787.jpg" -"2788" "Based on the histological section, what type of epithelium is present at the top of the image?" "Simple squamous epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "Stratified squamous epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2788.jpg" -"2789" "In the bottom of the image, what can be inferred about the densely aggregated cells with dark-stained nuclei?" "Transition to muscular tissue" "Normal skin dermis" "Presence of malignant cells" "Intense inflammatory response" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2789.jpg" -"2790" "When assessing the dermal-epidermal junction in the skin biopsy image, what type of alteration is appreciated?" "Altered interface with disruption of normal stratification" "Bullous pemphigoid with subepidermal blistering" "Lichenoid interface dermatitis with band-like infiltrate" "Psoriasiform hyperplasia with elongated rete ridges" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2790.jpg" -"2791" "What histological feature is indicated by the dark purple-staining structures seen within the epithelium of this skin tissue section?" "Necrotic debris" "Hemorrhage" "Keratinous material" "Melanin pigment" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2791.jpg" -"2792" "What cellular feature is predominant in this high-power field of the tissue section stained with H&E?" "Cells with hyperchromatic nuclei and high nuclear to cytoplasmic ratio" "Cells with large vesicular nuclei and abundant cytoplasm" "Cells with numerous mitotic figures and loss of polarity" "Cells with dense eosinophilic cytoplasm and pyknotic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2792.jpg" -"2793" "What is the pattern of endothelial cell lining observed in the vascular channels?" "Irregular multi-layering with occasional atypia" "Uniform single-layer lining without atypia" "Uniform multi-layering without atypia" "Regular multi-layering with consistent atypia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2793.jpg" -"2794" "How would you describe the architectural organization of the vascular tissue in this image?" "Organized and regularly patterned" "Regular with sporadic disorganized areas" "Haphazard lacking organized patterning" "Haphazard with organized areas" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2794.jpg" -"2795" "Based on the arrangement and morphology of the cells at the periphery of the inflammatory response, which type of reaction does the tissue most likely represent?" "Granulomatous reaction" "Lymphoid aggregate formation" "Glandular hyperplasia" "Acute inflammatory reaction" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2795.jpg" -"2796" "What cell type is predominantly present in the central region of this microscopic image, suggested by their characteristic nuclear morphology?" "Eosinophils" "Basophils" "Neutrophils" "Lymphocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2796.jpg" -"2797" "What tissue characteristic supports the diagnosis of a dermal spindle cell neoplasm?" "Abundant mitotic figures" "Presence of subcutaneous fat" "Disorganized cell structure" "High cellular polymorphism" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2797.jpg" -"2798" "Based on the appearance of the nuclei, what is the most likely observed cellular morphology in this tissue?" "Large, round nuclei with prominent nucleoli and abundant cytoplasm" "Hyperchromatic, pleomorphic nuclei with high mitotic activity" "Oval to elongated, spindle-shaped nuclei with abundant cytoplasm" "Small, uniform nuclei with scant cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2798.jpg" -"2799" "What is the histological feature of the prominent structure in the center of the image annotated with an arrow?" "Hyaline cartilage" "Purkinje fibers" "Ductus deferens" "Bronchiole" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2799.jpg" -"2800" "The epithelium lining the circular structure in the center of the image is best characterized as which of the following?" "Simple squamous epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2800.jpg" -"2801" "How would you characterize the regions around the cystic spaces predominantly, based on the cellular arrangement and density?" "Dense with fibroblastic activity" "Edematous with significant fluid accumulation" "Acutely inflamed with abundant neutrophils" "Avascular with paucity of cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2801.jpg" -"2802" "Considering the architecture observed, what is NOT represented in the tissue section?" "Thyroid follicles containing colloid" "Collagenous connective tissue surrounding epithelial lining" "Potential areas indicating a chronic reactive process" "Inflammatory cells concentrated around cystic structures" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2802.jpg" -"2803" "What is the morphology of the cellular clusters observed in this image?" "Well-differentiated tubular structures" "Circumscribed adipose tissue" "Uniform fibroblastic proliferation" "Invasive epithelial islands" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2803.jpg" -"2804" "Which feature in the image is characteristic of the exocrine pancreas involved in digestive enzyme secretion?" "Groups of cells surrounding clear lumens" "Cells with abundant pink cytoplasm" "Clusters of cells with basophilic granular cytoplasm" "Clusters of lighter-stained cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2804.jpg" -"2805" "What is the predominant architectural pattern observed in the outlined area of the tissue?" "Papillary" "Solid" "Trabecular" "Tubular" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2805.jpg" -"2806" "What cellular morphology is prominent within the cells lining the papillary structures?" "Intracellular mucin" "Rosette formations" "Cytoplasmic vacuolization" "Syncytial growth pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2806.jpg" -"2807" "What is the predominant extracellular matrix component observed in the tissue?" "Amorphous basophilic ground substance" "Hyalinized fibrous tissue" "Eosinophilic collagen bundles" "Adipose tissue with signet ring cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2807.jpg" -"2808" "What is the morphology of the cells within the tissue?" "Spindle-shaped with elongated nuclei" "Columnar with basally located nuclei" "Cuboidal with central round nuclei" "Round with prominent nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2808.jpg" -"2809" "In which labeled area do the cells appear to be organized into rounded or ovoid clusters with a cord-like pattern?" "Capsule" "Glomerulosa" "Fasciculata" "" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2809.jpg" -"2810" "Based on the uniformity of staining in the germinal centers, how would the visible polarity normally expected in these structures be described?" "The germinal centers have a monotonous appearance lacking visible polarity." "A distinct zonal arrangement with clearly identifiable layers of cell differentiation." "A clear difference with darkly staining centroblasts and more lightly staining centrocytes." "There is a variety in cell size and shape indicating different stages of cell maturation." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2810.jpg" -"2811" "Based on the microscopic view of this tissue specimen, which description best characterizes the predominant cell type observed?" "Cells with large eosinophilic cytoplasm and multiple nuclei" "Cells with dense, dark cytoplasm and central nucleus" "Cells with large white spaces and peripheral nucleus" "Cells with spindle shapes and elongated nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2811.jpg" -"2812" "What is the nature of nuclear morphology seen within the neoplastic cells in this image?" "Multinucleated giant cells with irregular nuclear outlines" "Monotonous and bland nuclear morphology with fairly isomorphic nuclei" "Marked pleomorphism with variations in size and shape of nuclei" "Presence of hyperchromatic and smudged nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2812.jpg" -"2813" "What does the eosinophilic layer shown at the top region of the image suggest about the tissue?" "Presence of a high concentration of elastic fibers" "A high degree of keratinization" "A large number of inflammatory cells" "Abundant mucopolysaccharide deposition" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2813.jpg" -"2814" "What is the characteristic feature of the peripheral region of the nodular structure?" "Highly vascularized area" "Prominent necrosis" "Dense connective tissue capsule" "Disorganized cellular architecture" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2814.jpg" -"2815" "What type of epithelial cell morphology is predominantly observed in the layer surrounding the apparent lumen or cavity?" "Squamous epithelium" "Columnar epithelium" "Cuboidal epithelium" "Transitional epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2815.jpg" -"2816" "Assuming a pathological context, which feature in the tissue section might indicate a myxoid neoplasm?" "Homogeneous staining of the extracellular matrix" "Presence of clear or 'mucoid' cytoplasm in rare cells" "Well-organized vascular structures" "Dense, eosinophilic cytoplasm in the epithelial lining" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2816.jpg" -"2817" "In the right side of the image, the layer beneath the trabecular meshwork exhibits a certain pattern in cell arrangement. How can this pattern be best described?" "Stratified squamous epithelium" "Palisading cells" "Orderly arrangement with parallel fibers" "Disorganized with pleomorphic cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2817.jpg" -"2818" "Upon examination of the area described as the potential canal of Schlemm, which of the following best characterizes the cellular pattern?" "Densely packed and circularly organized" "Homogenously distributed with abundant cytoplasm" "Disarrayed with significant anisocytosis" "Loosely arranged and widely spaced" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2818.jpg" -"2819" "Assessing the underlying connective tissue, what feature can be observed in the vessels present in this image?" "Perivascular lymphocytic infiltration" "Thrombosis within the vessel lumen" "Vasculitis with structural damage to vessel walls" "The presence of erythrocytes within the lumen" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2819.jpg" -"2820" "What is the histopathological feature highlighted by the areas enclosed in black outlines at the stratum corneum level?" "Acantholysis" "Parakeratosis" "Spongiosis" "Hyperkeratosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2820.jpg" -"2821" "Based on the morphology of the cells at the top layer of the epithelium, how do you describe the cytoplasm of these superficial cells?" "Ample with high keratin expression" "Ample with low keratin expression" "Scant with low keratin expression" "Scant with high keratin expression" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2821.jpg" -"2822" "Based on the observed histopathological features, which architectural pattern is evident in the distinct areas of cellular arrangement with small, uniform nuclei?" "Papillary architecture" "Cribriform pattern" "Solid patterning" "Trabecular configuration" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2822.jpg" -"2823" "What does the distribution and density of the darker purple areas within this tissue section imply?" "Represent regions of fibrosis or scarring" "Indicate areas of necrosis within the tissue" "Suggest the presence of dense clusters of lymphocytes" "Correspond to deposits of extracellular matrix proteins" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2823.jpg" -"2824" "Based on the histological features observed in the image, what is the predominant tissue type visible?" "Cardiac muscle showing intercalated discs" "Skeletal muscle with variable-sized fibers and peripheral nuclei" "Smooth muscle with spindle-shaped cells without striations" "Neoplastic tissue with dysplastic cellular changes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2824.jpg" -"2825" "What is the appearance of the structures indicated by the yellow arrow, and what do they represent?" "Eosinophilic fibers indicative of smooth muscle" "Basophilic clusters representing lymphoid tissue" "Acidophilic striations denoting skeletal muscle" "Pale cytoplasm and peripheral nuclei characteristic of adipocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2825.jpg" -"2826" "Which of the following best describes the epithelial structure marked by the red arrow in the tissue image?" "A mucous tubule with pale-staining mucous cells" "An acinar structure with secretory cells" "A striated duct with columnar epithelial lining" "An adipocyte with a signet ring-like appearance" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2826.jpg" -"2827" "Based on the density and appearance of the cells within some tubules, what pathological condition could be present?" "Metaplasia" "Hyperplasia" "Cellular atrophy" "Tubular obstruction" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2827.jpg" -"2828" "Based on the lung architecture and the types of cells present, what phase of lung injury is likely represented in this image?" "Organizing phase" "Early fibrotic phase" "Resolution phase" "Acute inflammatory phase" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2828.jpg" -"2829" "What is the predominant cell type visible in this microscopic image indicative of a glandular organ?" "Adipocytes" "Skeletal muscle cells" "Eosinophilic epithelial cells" "Mucous cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2829.jpg" -"2830" "Which structural feature is supporting the glandular cells evident in this image?" "Dense irregular connective tissue" "Hyaline cartilage" "Elastic fibers" "Fibrous connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2830.jpg" -"2831" "Based on the morphology observed in the image, what is the nature of the ductal changes present within the tissue?" "Comedo necrosis" "Sclerosing adenosis" "Ductal hyperplasia" "Cribriform pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2831.jpg" -"2832" "Analyzing the stroma surrounding the ducts in the image, what describes its cellularity?" "Myxoid" "Desmoplastic" "Increased cellularity" "Edematous" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2832.jpg" -"2833" "How can areas of epidermal disruption be characterized in the tissue section shown?" "Focal points where blue-staining collagen appears to penetrate the red-stained epithelium" "Regions where the blue-stained material is absent" "Homogeneous pinkish-red hue across the epidermis" "Areas showing consistent blue-staining throughout the depth of the tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2833.jpg" -"2834" "Based on the cellular morphology, what type of epithelium is observed at the top layer of the tissue in the image?" "Transitional epithelium" "Simple squamous epithelium" "Simple columnar epithelium" "Stratified squamous epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2834.jpg" -"2835" "In the image, which cells likely represent an infiltrative pathological process?" "Cells with large, round nuclei at the top" "Spindle-shaped cells in the middle layer" "Cells with dark, shrunken nuclei and eosinophilic cytoplasm" "Cells with clear cytoplasm and peripheral nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2835.jpg" -"2836" "What does the heterogeneity of the surrounding tissue likely represent?" "Muscle tissue" "Adipose tissue" "Necrotic tissue" "Connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2836.jpg" -"2837" "What does the morphology of the glomerular capillary loops suggest?" "Hyaline deposition" "Normal capillary loop structure" "Endocapillary proliferation" "Thinning of the capillary walls" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2837.jpg" -"2838" "Assessing the spaces meant for the capillary lumen, what can be observed?" "Dilatation suggesting aneurysmal change" "Narrowed or obliterated spaces" "Evidence of excessive red blood cell accumulation" "Clear demarcation and ample lumen space" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2838.jpg" -"2839" "What type of deposition is identified by the dark purple, crystalline deposits in the tissue?" "Lipid accumulation" "Amyloid deposits" "Calcifications" "Hematoma" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2839.jpg" -"2840" "Considering the appearance of the tissue section, which vascular structure is most likely affected by the abnormal cell proliferation?" "Small arterioles" "Large muscular arteries" "Lymphatic vessels" "Venous channels" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2840.jpg" -"2841" "What staining pattern does CK7 predominantly exhibit in the atypical cells pictured?" "Membranous" "Nuclear" "Cytoplasmic" "Extracellular matrix" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2841.jpg" -"2842" "Based on the tissue morphology, what might be the reason for the appearance of increased eosinophilic (pink-stained) areas surrounding some of the hair follicles?" "Abundance of collagen fibers" "Presence of melanin" "Accumulation of keratin" "Increased number of immune cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2842.jpg" -"2843" "Which features observed in the image would typically make it difficult to distinguish between lymphocytes and plasma cells?" "The presence of multi-lobed nuclei" "The size and color of the cytoplasm" "The shape and positioning of the nuclei" "The presence of a perinuclear halo" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2843.jpg" -"2844" "Based on the cellular morphology and density, what does the tissue architecture in this image primarily indicate?" "Atrophy of the tissue" "Acute inflammatory response" "Chronic inflammation with fibrosis" "Well-preserved tissue architecture" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2844.jpg" -"2845" "Focal areas of pale-staining within the tissue section could suggest several changes. Which of the following is LEAST supported by the observed pale-staining regions in the image?" "Fatty metamorphosis" "Hyaline degeneration" "Myxoid change" "Necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2845.jpg" -"2846" "Are there any indications of a cribriform pattern in this tissue section?" "Yes, but the pattern is only present in isolated regions of the tissue" "No, there is no cribriform pattern, but sieve-like spaces are present within the tissue matrix" "Yes, a cribriform pattern is visible throughout the sample" "No, the tissue exhibits a solid growth pattern without any spaces" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2846.jpg" -"2847" "As observed in the slide, what feature of the muscularis aids in the contractile functions of the oviduct?" "The dense, irregular arrangement of muscle fibers" "The presence of striations within the muscle fibers" "The appearance of intercalated discs between muscle fibers" "The layered structures with varying pink hues" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2847.jpg" -"2848" "Upon close observation, what are the characteristic features of the parietal (oxyntic) cells in the gastric glands?" "Cells with a darker staining cytoplasm and central nuclei" "Cells with a large central nuclei and acidophilic cytoplasm" "Cells with a foamy cytoplasm and peripheral nuclei" "Cells with a lighter staining cytoplasm and multiple nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2848.jpg" -"2849" "What feature is characteristic of the cellular morphology seen in this high-power field of a tissue section?" "Uniform small lymphocytes with dense chromatin" "Predominance of small round cells with high nucleo-cytoplasmic ratio" "Abundant cytoplasm with cells exhibiting multilobed or binucleate nuclei" "Uniformly distributed lymphocytes with no atypical cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2849.jpg" -"2850" "Considering the immunohistological characteristics observed, which of the following conditions is this tissue pattern least likely to represent?" "Lymphoid hyperplasia" "Reactive lymphadenopathy" "Lymphoma" "Sarcoidosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2850.jpg" -"2851" "How would you describe the cellular density and distribution in this tissue?" "Sparsely distributed and organized" "Densely packed and organized" "Sparsely distributed and disorganized" "Densely packed and disorganized" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2851.jpg" -"2852" "What is the characteristic appearance of the large epithelial cells observed in this image?" "Necrosis with surrounding inflammatory response" "Multinucleation with perinuclear halo" "Large cytoplasmic inclusions with marginal nuclei" "Hyperchromatic nuclei with increased mitotic activity" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2852.jpg" -"2853" "Based on the microscopic morphology of the surface cells, what characteristic feature is observed in the squamous epithelium?" "Pyknotic nuclei" "Large nucleoli" "Prominent cytoplasmic vacuolization" "Multinucleation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2853.jpg" -"2854" "Analyzing the underlying connective tissue layer beneath the epithelium, which feature is prominent in the lamina propria?" "Blood vessels" "Adipose tissue" "Inflammatory infiltrate" "Collagen bundles" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2854.jpg" -"2855" "What feature best characterizes the most superficial layer of the skin section observed?" "Hyperkeratosis" "Acantholysis" "Hypergranulosis" "Parakeratosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2855.jpg" -"2856" "Based on the arrangement of fibrous tissue seen in this image, what pattern of fibrosis is most apparent?" "Disordered diffuse fibrosis" "Irregular interstitial fibrosis" "Concentric, onion-skin-like fibrosis" "Densely packed parallel fibrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2856.jpg" -"2857" "Based on the image, which glandular architectural change is not consistent with normal intestinal mucosa?" "Regular spacing between adjacent glands" "Elongated finger-like projections of villi" "Basally located nuclei in a single layer" "Crowding and architectural distortion of glands" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2857.jpg" -"2858" "The circular areas devoid of nuclei suggest the presence of which liver structure?" "Central veins" "Lipid droplets within hepatocytes" "Portal tracts" "Liver sinusoids" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2858.jpg" -"2859" "Within the lumen of the tubules, what type of substance can be observed?" "Basophilic secretions" "Eosinophilic secretions" "Calcified bodies" "Clear and homogenous fluid" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2859.jpg" -"2860" "In the image, what does the presence of eosinophils in the dermis suggest?" "Sign of chronic inflammation" "Indication of acute infection" "Result of neoplastic activity" "Evidence of early-stage blister formation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2860.jpg" -"2861" "What can be deduced about the glomerular cellularity in the depicted renal tissue section?" "Indicative of glomerular proliferation" "Suggests normal glomerular cellularity" "Suggestive of decreased glomerular cell count" "Indicative of glomerular atrophy" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2861.jpg" -"2862" "Based on the cellular characteristics seen, how would the degree of hypercellularity within the glomerulus be described?" "The glomerulus has a normal cell count" "The glomerulus shows marked hypercellularity" "There is a slight increase in the number of cells within the glomerulus" "The glomerulus displays an overabundance of cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2862.jpg" -"2863" "What is the predominant color of the extracellular matrix surrounding the chondrocytes in the observed tissue?" "Bright red" "Vivid blue" "Dark purple" "Light pink" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2863.jpg" -"2864" "Considering the morphology of the chondrocytes, what can we infer about their activity in this region of cartilage?" "The chondrocytes exhibit morphological signs of degeneration and apoptosis" "The chondrocytes are uniformly dispersed and do not display a pattern of active proliferation or matrix production" "The chondrocytes are densely packed and showing signs of high proliferative activity" "The chondrocytes are enlarged and show extensive vacuolization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2864.jpg" -"2865" "What evidence of a reactive process can be observed in the epidermis of this histological section?" "Occurrence of melanocyte proliferation" "Presence of parakeratosis" "Formation of granulomas" "Elongation of rete ridges" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2865.jpg" -"2866" "Assessment of the nuclei in this specimen reveals which of the following features?" "Nuclei with prominent nucleoli and perinuclear halos" "Enlarged nuclei with significant pleomorphism" "Uniform nuclei with no variation in size or shape" "Darkly stained nuclei with signs of hyperchromasia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2866.jpg" -"2867" "Based on the arrangement of the cells, what is the organization pattern observed in this soft tissue neoplasm?" "Cells dispersed singly without organization" "Cells arranged in a glandular pattern" "Cells organized in cords or chains" "Cells organized in nests" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2867.jpg" -"2868" "What feature is evident in the glandular structures of this tissue section?" "Atrophic glands with a reduced number of cells" "Uniform glands with rare mitotic figures" "Hyperplastic glands with papillary infoldings" "Cystic dilation with an expanded lumen" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2868.jpg" -"2869" "Based on the observable characteristics in this microscopic image, what is the likely nature of these cells?" "Benign nevocytes with no apparent mitotic activity" "Dysplastic nevus cells with severe atypia" "Basal cell carcinoma cells with peripheral palisading" "Melanoma cells with high mitotic activity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2869.jpg" -"2870" "What does the morphology of the tissue nodule suggest about its nature?" "Infiltrative growth pattern" "Poorly circumscribed margins" "Well-demarcated lesion" "Significant pleomorphism" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2870.jpg" -"2871" "When examining the stromal tissue underneath the epithelial lining, what do the observed features suggest?" "Dense fibrous connective tissue" "Loose connective tissue with no remarkable pathology" "Significant stromal invasion by neoplastic cells" "Acute inflammatory response with prominent neutrophil infiltration" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2871.jpg" -"2872" "Upon microscopic examination, the cells appear to show a characteristic feature indicative of a certain type of cellular differentiation. What cellular feature is most prominent in this image?" "Intracytoplasmic lipid accumulation" "Extensive cytoplasmic fibrillary structures" "Granular cytoplasm with heavy pigmentation" "Abundant eosinophilic cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2872.jpg" -"2873" "Analyzing the nuclei within the cells, what characteristic can be observed?" "Nuclei exhibiting karyolysis with loss of nuclear integrity" "Nuclei exhibiting hyperchromasia, suggesting high nuclear-to-cytoplasmic ratios" "Nuclei that are small and uniform with inconspicuous nucleoli" "Nuclei with prominent nucleoli and clear cytoplasmic boundaries" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2873.jpg" -"2874" "Based on the observed tissue architecture, what is the level of organization demonstrated in this microscopic image?" "Poorly differentiated with a lack of uniformity and organization" "Highly organized with repetitive and predictable structures" "Moderate anaplasia with some retention of normal tissue architecture" "Well-differentiated with clear structural organization" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2874.jpg" -"2875" "Based on the image, what is the condition of the epidermis?" "Normal stratification retained" "Psoriasiform hyperplasia" "Atrophic changes observed" "Hyperkeratosis with parakeratosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2875.jpg" -"2876" "Judging by the cellular morphology, which feature is NOT readily apparent in this field of view?" "Clear cytoplasm" "Uniform nuclei" "Eosinophilic cytoplasm" "Mitotic figures" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2876.jpg" -"2877" "How does the stromal tissue surrounding the epithelial-lined cystic lesions appear in this microscopic image?" "Loose and myxoid" "Predominantly adipose tissue" "Dense and fibrous" "Highly cellular with numerous mitotic figures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2877.jpg" -"2878" "What can be said about the presence of inflammatory cells within the stroma in the illustrated histopathological sample?" "Infiltration by eosinophils is predominant" "A marked infiltration of inflammatory cells is present" "A granulomatous inflammation pattern is observed" "There is no significant inflammatory cell infiltration visible" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2878.jpg" -"2879" "Based on the pattern of spindle cells observed in the image, which histological arrangement is most accurately represented?" "Palisading arrangement" "Fascicular growth pattern" "Storiform pattern" "Herringbone pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2879.jpg" -"2880" "Regarding the lipocytes (fat cells) present in the image, which description most accurately reflects their morphology and arrangement?" "Hyperplastic and densely packed" "Atrophic and widely dispersed" "Compressed and scattered resembling a honeycomb" "Swollen and arranged in clusters" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2880.jpg" -"2881" "Considering the potential presence of a malignant process, what does the pink-staining extracellular material in this histological image likely represent?" "Mucinous secretions" "Collagen deposition or scarring" "Edematous stroma" "Necrotic tissue debris" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2881.jpg" -"2882" "The connective tissue surrounding the cystic structures predominantly demonstrates which characteristic staining property?" "Densely pink staining suggesting collagenous stroma" "Deep red-purple indicative of mineralization" "Light blue mucoid material typical for myxoid stroma" "Darkly staining consistent with hemosiderin deposition" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2882.jpg" -"2883" "What does the presence of eosinophilic material within the luminal spaces of gland-like structures suggest?" "Necrotic debris" "Hemorrhage" "Secretory activity" "Inflammatory infiltrate" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2883.jpg" -"2884" "The duct-like structures observed in the micrograph are indicative of which of the following?" "Hyperplastic glandular tissue with evidence of secretion" "Active angiogenesis with immature blood vessel formation" "Dysplastic changes with significant nuclear atypia" "Necrotic tissue with loss of cellular detail" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2884.jpg" -"2885" "By examining the given histological section, what is the nature of the cell formation within the parenchyma?" "Lymphocytic infiltration" "Granulomatous inflammation" "Fibroadenomatous hyperplasia" "Squamous metaplasia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2885.jpg" -"2886" "Which feature in the histological slide suggests active bone formation?" "Multinucleated giant cells" "Peripheral blood vessels" "Uniform pink-stained areas evenly distributed" "Darker, irregular shapes throughout the tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2886.jpg" -"2887" "Given the histological appearance and architecture of the tissue, what is the most likely diagnosis?" "Ductal carcinoma in situ" "Lobular carcinoma in situ" "Invasive ductal carcinoma" "Atypical ductal hyperplasia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2887.jpg" -"2888" "Based on the cytoplasmic appearance of the cells in the transitional layer, what is a likely cellular activity occurring in these cells?" "Lipid storage" "High levels of protein synthesis" "Active mucin secretion" "Extensive phagocytosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2888.jpg" -"2889" "Based on the irregular dispersion of the granulomas within the tissue observed in the image, which of the following conditions is most likely represented?" "Rheumatoid arthritis" "Organizing pneumonia" "Sarcoidosis" "Tuberculosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2889.jpg" -"2890" "Considering the fibrous nature of the stroma, what additional feature can be observed?" "Extensive necrosis throughout the stroma" "Scattered inflammatory cells within the stroma" "A rich supply of blood vessels in the stroma" "High mitotic activity within the stromal cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2890.jpg" -"2891" "The variability in alveolar spaces with some appearing collapsed and others dilated is most indicative of what pathology?" "Normal age-related changes" "Pulmonary fibrosis" "Bronchopneumonia" "Emphysema" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2891.jpg" -"2892" "Considering the observable cell division in this tissue sample, which description best fits the mitotic figures?" "Mitotic figures with evenly spaced chromosomes" "No visible mitotic activity" "Abnormal and atypical mitotic figures" "Regular and symmetrical mitotic figures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2892.jpg" -"2893" "Based on the histological features observed in the dermal layer, how would you describe the arrangement of the spindle-shaped cells within the lesion?" "The cells form a well-circumscribed nodule with a clear encapsulation." "Normal collagenous structure of dermis appears preserved without infiltration." "The smooth muscle bundles exhibit an infiltrative growth pattern disrupting the normal collagen." "Spindle-shaped cells are arranged in a concentric whorled pattern." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2893.jpg" -"2894" "What characteristic is shared by most of the cells in the image?" "Dense, homogeneously stained nuclei" "Light staining of the cytoplasm" "Presence of nucleoli" "Multilobed nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2894.jpg" -"2895" "What is the characteristic of the cytoplasm of the large epithelioid cells visible in the image?" "Abundant and pale or clear" "Dense and basophilic" "Abundant with dark granular content" "Scarce and eosinophilic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2895.jpg" -"2896" "Based on the appearance of the extracellular material in the image, which of the following best describes its morphology?" "Fibrous with a dark blue hue" "Eosinophilic with irregular patterns" "Calcified with a greenish tinge" "Amorphous and basophilic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2896.jpg" -"2897" "Based on the cellular arrangement, what type of epithelium is present in the glandular structures seen in the image?" "Cuboidal epithelium" "Columnar epithelium" "Squamous epithelium" "Transitional epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2897.jpg" -"2898" "In this histological image, what is the predominant type of tissue pattern visible by the irregular, pink-stained material?" "Woven bone" "Hyaline cartilage" "Adipose tissue" "Dense regular connective tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2898.jpg" -"2899" "Based on the histological features, what stage of bone development does the tissue in this image most likely represent?" "Mature bone remodeling" "Endochondral ossification" "Late-stage cartilage ossification" "Early-stage bone development" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2899.jpg" -"2900" "Based on the histopathological features, what is the most likely explanation for the variability in nuclear size and prominence within the hepatocytes?" "Benign hepatic regeneration" "Normal variation in hepatocyte nuclei" "Hemochromatosis-induced cellular change" "Dysplasia or malignancy" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2900.jpg" -"2901" "The eosinophilic areas of the image suggest the presence of:" "Dense collagen bundles or fibrosis" "Abundant cytoplasm in the neoplastic cells" "Extensive necrosis within the tumor" "High vascularity with increased angiogenesis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2901.jpg" -"2902" "What can be inferred about the cytoplasm of the fibroblasts present in the stroma?" "Sparse and basophilic" "Cytoplasmic extensions forming a reticular pattern" "Abundant and eosinophilic" "Vacuolated with lipid inclusions" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2902.jpg" -"2903" "What is the predominant feature observed in this histological image?" "Neoplastic cell proliferation" "Granulomatous inflammation" "Multinucleated giant cells" "Eosinophilic necrosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2903.jpg" -"2904" "What observation in the image might suggest tissue damage involving adipocytes?" "Regularly shaped lymphocytes dispersed evenly throughout the tissue" "Small, normal-sized lymphocytes in close proximity to the adipocytes" "Adipocytes with evenly stained, homogenous cytoplasm" "Large lymphocytes with hyperchromatic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2904.jpg" -"2905" "Which of the following best describes the nuclear characteristics of the epithelial cells seen in the crypt?" "Small, dark-staining nuclei with no visible nucleoli" "Anisonucleosis with no visible nucleoli" "Uniform nuclei with inconspicuous nucleoli" "Enlarged and hyperchromatic nuclei with prominent nucleoli" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2905.jpg" -"2906" "What type of cells can be seen in the layer outside of the palisaded zone?" "Large multinucleated giant cells" "Round cells with hyperchromatic nuclei and abundant cytoplasm" "Small, round cells with dark-staining nuclei and scant cytoplasm" "Spindle-shaped cells with vesicular nuclei and abundant eosinophilic cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2906.jpg" -"2907" "What distinctive feature can be observed in this microscopic image suggestive of a specific type of cell lineage?" "Squamous cell keratinization" "Glandular epithelial secretions" "Muscle tissue striation" "Adipose tissue differentiation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2907.jpg" -"2908" "What aspect of the tissue architecture can be determined from this image?" "The presence of well-defined layers of cells" "The regular distribution of cells throughout the tissue" "A clear pattern of maturation from top layers to deeper ones" "Disrupted architecture with lack of recognizable maturation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2908.jpg" -"2909" "What is the predominant feature observed on the surface of the epithelium in this histopathological slide?" "Thickened, eosinophilic stratum corneum" "Presence of dyskeratotic cells" "Loss of the granular cell layer" "Thin, atrophic stratum corneum" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2909.jpg" -"2910" "Examining the architecture of the tissue, which feature is consistent with a diagnosis of verrucous carcinoma?" "Severe cellular atypia" "Elongated rete ridges" "Deep tissue invasion" "Central fibrovascular cores within papillae" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2910.jpg" -"2911" "What is the morphological characteristic of the cells surrounding the pseudovascular spaces?" "The cells have abundant eosinophilic cytoplasm with high nuclear-to-cytoplasmic ratio" "The cells display significant nuclear pleomorphism and numerous mitotic figures" "The cells have hyperchromatic nuclei with prominent nucleoli" "The cells are densely packed with a spindle and oval morphology" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2911.jpg" -"2912" "What feature supports the benign nature of the lesion depicted in the microscopic image?" "Presence of pseudovascular spaces without a structured endothelial lining" "Presence of disorganized growth without a structured endothelial lining" "Presence of tumor cells with high mitotic activity" "Presence of true vascular spaces with a structured endothelial lining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2912.jpg" -"2913" "How would you classify the cellular architecture observed in the periphery of these clear spaces?" "Dispersed melanoma cells with atypical features" "Organized columnar epithelial cells with glandular structures" "Densely packed nevus cells with benign morphology" "Necrotic and pleomorphic cells suggestive of high-grade malignancy" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2913.jpg" -"2914" "Based on the histological features observed, which tissue architecture abnormality is evident in this section?" "Normal arrangement of fibrocollagenous stroma" "Duct-like structures lined by epithelial cells" "Increased adipose tissue infiltration" "Disorganization of the epithelial layers" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2914.jpg" -"2915" "What is the predominant feature of the cells within the densely packed collection observed in the microscopic image?" "Scant cytoplasm and round nuclei" "Abundant cytoplasm and irregular nuclei" "Well-differentiated squamous cells" "Multinucleated giant cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2915.jpg" -"2916" "How would you describe the arrangement of nuclei in the multinucleated giant cells seen in this tissue image?" "Arranged at the periphery of the cytoplasm" "Encapsulated in a separate membrane" "Dispersed randomly throughout the cytoplasm" "Centralized within the cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2916.jpg" -"2917" "What alteration in the hepatocytes can be inferred from the microscopic image?" "Hyperplasia with increased cell number" "Atrophy with thin, compressed plates" "Hypertrophy with enlarged cell size" "Steatosis with fat accumulation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2917.jpg" -"2918" "What does the presence of very eosinophilic strands with a branching or arborizing pattern throughout the sample suggest?" "Necrosis within the tissue" "Dense collagenous connective tissue" "Accumulation of immune cells" "Hyperplasia of epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2918.jpg" -"2919" "Upon examining the deeper portions of the crypt bases in the image, what can be inferred?" "The crypt bases show no evidence of salivation or secretory activity" "There is a significant increase in secretory activity in the lower one-third of the crypts" "The deep crypts are fully dilated similar to the upper glandular structures" "There is a clear separation or transition between the crypt bases and the dilated glands" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2919.jpg" -"2920" "How would you describe the extracellular matrix material visible in this image?" "Collagen-rich, densely eosinophilic" "Amyloid deposition with apple-green birefringence" "Mucopolysaccharide-rich, pale-staining" "Fibrinoid material with necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2920.jpg" -"2921" "Which component of the tissue can be inferred from the presence of round to oval structures with a darkly stained rim in the lighter region?" "Blood vessels" "Nerve tissue" "Collagen bundles" "Muscle fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2921.jpg" -"2922" "What feature is observed in the nuclei of the cells in this tissue section?" "Uniformly sized and shaped nuclei" "Mononucleated cells" "Nuclei with prominent nucleoli" "Hyperchromatic nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2922.jpg" -"2923" "What is the nuclear appearance of the cells in the provided tissue section?" "Uniformly hypochromatic nuclei" "Monomorphic nuclei with consistent shapes" "Uniformly pale nuclei with prominent nucleoli" "Hyperchromatic nuclei with variable shapes and sizes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2923.jpg" -"2924" "What is the observed pattern of cell arrangement in this tissue section?" "Glandular structures with distinct lumina" "Disorganized clusters without a specific pattern" "Single-file linear arrangements" "Nests or clusters suggestive of glandular differentiation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2924.jpg" -"2925" "Based on the microscopic features seen in this tissue section, what is the most likely pathological process observed?" "Neutrophilic infiltration" "Hyalinization" "Lymphocytic infiltration" "Hyperplasia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2925.jpg" -"2926" "What observation can be made regarding the normal cytological architecture of this endocrine gland tissue?" "It contains a large number of mitotic figures" "It shows significant cellular pleomorphism" "It lacks distinct cell boundaries and nuclei" "It presents with distinct cell boundaries and nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2926.jpg" -"2927" "Based on the examination of the tissue architecture, what is the most likely nature of the cellular arrangement?" "Highly irregular with variably sized lobules" "Regular with well-defined, uniform lobules" "Haphazard with significant interlobular edema" "Disorganized with infiltrative margins" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2927.jpg" -"2928" "Assessing the structural characteristics of the tissue, what can be inferred about the presence of atypical features?" "There are frequent mitotic figures evident" "No obvious invasion into surrounding tissues is present" "Significant pleomorphism and hyperchromasia are observed" "There is a high degree of nuclear atypia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2928.jpg" -"2929" "Considering the pale pink to clear spaces in this tissue section, what is the most likely composition of these areas?" "These are areas of fatty infiltration within the connective tissue." "They represent amorphous material, possibly cryoglobulins within interstitial spaces or vessel lumens." "The spaces are indicative of hyaline cartilage within the connective tissue." "They suggest the presence of calcifications within the tissue." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2929.jpg" -"2930" "Based on the granulomatous process indicated by the tightly packed mononuclear cells surrounding the central structure, which pathology might be suggested by this image?" "Tuberculosis" "Osteosarcoma" "Rheumatoid arthritis" "Leprosy" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2930.jpg" -"2931" "What does the presence of vacuolated cells in lobulated collections strongly suggest about the tissue type toward the center and right of the image?" "Sebaceous glands" "Adipose tissue" "Neural tissue" "Skeletal muscle" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2931.jpg" -"2932" "Based on the histologic features seen in the image, what type of tissue is predominantly displayed?" "Keratinized stratified squamous epithelium" "Glandular epithelium" "Muscular tissue" "Neurogenic tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2932.jpg" -"2933" "What evidence of pathology can be identified in the stroma of the tissue?" "Lymphocytic and plasma cell infiltration" "Neutrophilic infiltration" "Goblet cell hyperplasia" "Squamous cell metaplasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2933.jpg" -"2934" "Based on the visual evidence provided in the image, what type of stroma can be inferred from the tissue matrix?" "Chondroid matrix" "Osteoid matrix" "Lipomatous stroma" "Myxoid stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2934.jpg" -"2935" "What histopathological feature is prominently seen in the stratum corneum of the lesion?" "Orthokeratosis" "Parakeratosis" "Acantholysis" "Hypergranulosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2935.jpg" -"2936" "What feature of the nuclei in the lesion suggests a high cellular turnover?" "Presence of prominent nucleoli" "Multinucleated giant cells" "Uniform and small nuclei" "Hyperchromatic and irregular nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2936.jpg" -"2937" "Based on the arrangement of the cells within the tissue, what can be inferred about the architecture?" "The cellular architecture demonstrates uniformity and organization" "The cellular architecture is polarized with one end of the cell different from the other" "The cellular architecture shows tightly packed cells with minimal intercellular spaces" "The cellular architecture shows disorganized structure with loss of regular patterning" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2937.jpg" -"2938" "In the given image, what is the orientation of the nuclei within the surface epithelial cells?" "Centrally located" "Basally located" "Apically located" "Randomly dispersed" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2938.jpg" -"2939" "Based on the image provided, what is the most distinguishing feature of the gastric glands within the tissue?" "Branching tubular structure" "Cilia on the apical surface" "Presence of goblet cells" "Gastric pits leading to gastric glands" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2939.jpg" -"2940" "What is the primary shape of the cells observed in the histological image?" "Round to oval" "Polygonal" "Cuboidal" "Spindle-shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2940.jpg" -"2941" "How would you describe the nuclei of the cells in this tissue section?" "Small and hypo chromatic " "Elongated and hyperchromatic" "Round with prominent nucleoli" "Bi-nucleated with pale chromatin" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2941.jpg" -"2942" "Based on the underlying histological features, what is the likely condition affecting the epithelial tissue displayed in the specimen?" "Psoriasis" "Lichen planus" "Pityriasis rosea" "Epidermodysplasia verruciformis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2942.jpg" -"2943" "Based on the structures observed in the image, which type of gland might be identified by a lobular appearance and pale staining due to its content?" "Salivary gland" "Eccrine sweat gland" "Sebaceous gland" "Mammary gland" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2943.jpg" -"2944" "Based on the tissue organization and cell types observed in this image, what kind of tissue are we most likely examining?" "Connective tissue" "Nervous tissue" "Muscle tissue" "Epithelial tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2944.jpg" -"2945" "What type of epithelium is lining the cystic structure as observed in the image?" "Transitional epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2945.jpg" -"2946" "Based on the absence of specific features in the image, which condition seems less likely?" "Inflamed epidermal inclusion cyst" "Dermoid cyst" "Keratinizing cyst" "Odontogenic cyst" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2946.jpg" -"2947" "How would you best describe the distribution of chromatin within the nuclei of the cells in this image?" "Showing multiple prominent nucleoli" "Hyperchromatic and clumped" "Finely distributed and bland" "Uneven with prominent nucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2947.jpg" -"2948" "Based on the observed histological features, what type of blood vessel is depicted in this image?" "Artery" "Lymphatic vessel" "Vein" "Capillary" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2948.jpg" -"2949" "What is the morphology of the suspected pathogenic structures within this tissue?" "Spindle-shaped with elongated nuclei" "Rounded with clear halos" "Irregular clusters without distinct borders" "Biconcave discs without nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2949.jpg" -"2950" "Based on the morphology shown in the image, what best describes the arrangement of the cells immediately adjacent to the tissue labeled 'A'?" "There are layers of cardiac muscle cells visible." "The cells are arranged in a tightly packed single layer." "The nearby cells are closely packed in multiple layers." "The cells exhibit a loosely arranged, edematous stroma." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2950.jpg" -"2951" "Which cells are present in the basal layer of this epithelium that are indicative of a possible inflammatory process?" "Cells with halo-like appearance" "Cells with increased mitotic figures" "Cells with large, hyperchromatic nuclei" "Cells with prominent desmosomes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2951.jpg" -"2952" "What type of cell arrangement is observed at the periphery of the cell islands?" "Cuboidal cells with centrally located nuclei" "Columnar cells with nuclei polarized away from the center" "Spindle-shaped cells with hyperchromatic nuclei" "Squamous epithelial cells with clear cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2952.jpg" -"2953" "Based on the microscopic features observed in the image, which histological pattern is most consistent with the architecture of the presented tissue sample?" "Uniformly distributed lymphoid follicles with well-defined germinal centers" "Densely packed spindle cells forming a storiform pattern" "Nodular formations separated by less cellular areas" "Sheets of undifferentiated cells with no specific architecture" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2953.jpg" -"2954" "Based on the cellular morphology, what type of cellular origin do the cells most likely have?" "Neural origin" "Hematopoietic origin" "Mesenchymal origin" "Epithelial origin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2954.jpg" -"2955" "Based on the organization of the tissue on the left side of the image, what type of normal histological structure is most likely depicted?" "Simple columnar epithelium" "Adipose tissue" "Skeletal muscle" "Nervous tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2955.jpg" -"2956" "What is the appearance of the stroma as seen in the image?" "Homogenous cellularity throughout" "Presence of subtle vascular structures" "Consistent fibroblastic cell density" "Avascular connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2956.jpg" -"2957" "In the provided image, what is the orientation of the nuclei within the epithelial cells lining the mucinous structures?" "Basally oriented nuclei" "Centrally oriented nuclei" "Randomly scattered nuclei" "Apically oriented nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2957.jpg" -"2958" "What is the most predominant feature of the cells observed in this pathological sample?" "Fibroblastic proliferation with collagen deposition" "Spindle-shaped cells with small, hyperchromatic nuclei" "Cells with abundant pale to clear cytoplasm and large nuclei" "Lymphocyte infiltration with germinal centers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2958.jpg" -"2959" "How would you describe the overall arrangement of the collagen fibers within the connective tissue in this image?" "Hyalinized and acellular" "Loose and disorganized" "Dense and parallel" "Regular and basket-woven" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2959.jpg" -"2960" "What is the predominant morphological feature of the inflammatory cells visible within the tissue?" "Hypersegmented neutrophils" "Multinucleated giant cells" "Lymphocytes with large nuclei" "Eosinophils with bilobed nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2960.jpg" -"2961" "Assessing the epithelial-dermal junction, what is the condition of the epithelium in this image?" "Well delineated with clear basement membrane" "Acanthotic with elongated rete ridges" "Not well delineated, indicating potential pathology" "Hyperplastic with increased layers of cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2961.jpg" -"2962" "The pattern of inflammation observed in this tissue specimen is most likely caused by what type of response?" "Autoimmune response leading to chronic inflammation" "Acute inflammatory response with predominance of neutrophils" "Acute inflammatory response with predominance of lymphocytes" "Granulomatous inflammation with macrophage presence" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2962.jpg" -"2963" "Based on the observed staining pattern, which marker might be predominantly expressed in the darker stained areas?" "Cytokeratin" "Vimentin" "S100" "CD45" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2963.jpg" -"2964" "What can be inferred about the inflammatory infiltrate in the surrounding tissue of the affected epithelium?" "It consists mainly of lymphocytes" "There is no significant inflammatory infiltrate present" "It is composed mainly of eosinophils" "It is predominantly composed of neutrophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2964.jpg" -"2965" "Based on the arrangement of the cells in the upper portion of the image, which pattern is NOT seen?" "Rosette structures" "Irregular clusters" "Nest formations" "Trabecular pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2965.jpg" -"2966" "What is the predominant staining characteristic of the cells in this histological image?" "Basophilic with blue-purple staining" "Eosinophilic with pink-red staining" "Acidophilic with orange staining" "Neutrophilic with no distinct color preference" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2966.jpg" -"2967" "Within this tissue sample, how would you characterize the nuclear-to-cytoplasmic ratio observed?" "High nuclear-to-cytoplasmic ratio with small nuclei" "Low nuclear-to-cytoplasmic ratio with small nuclei" "Low nuclear-to-cytoplasmic ratio with large nuclei" "High nuclear-to-cytoplasmic ratio with large nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2967.jpg" -"2968" "Based on the appearance of the surrounding tissue architecture, what is the observable condition of the dermal layer?" "The dermal layer shows signs of acute inflammation" "There is an extensive collagen deposition in the dermal layer" "The dermal layer contains excessive mucin" "There is a disruption of the normal dermal extracellular matrix" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2968.jpg" -"2969" "What type of unique cells can be identified scattered throughout the tissue?" "Foamy macrophages" "Reed-Sternberg cells" "Multinucleated giant cells" "Small lymphocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2969.jpg" -"2970" "In this histological section of the lesion, how would you describe the morphology of the cells within the aggregations?" "Cells vary significantly in size and shape, with evidence of severe pleomorphism" "Cells exhibit a high degree of anisocytosis and anisokaryosis" "Cells are generally uniform in appearance with eosinophilic cytoplasm and centrally located nuclei" "Cells show abundant cytoplasm with peripheral displacement of nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2970.jpg" -"2971" "Based on the presence of specific structures within the cells, what potential diagnosis does this tissue section suggest?" "Neuroendocrine tumor" "Sarcoma" "Endometrial carcinoma" "Lymphoma" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2971.jpg" -"2972" "Based on the structures observed in the image, what is the likely function of the tissue?" "Olfaction" "Mechanoreception" "Secretion" "Absorption" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2972.jpg" -"2973" "Based on the appearance of the stromal cells closest to the surface, which phase of the endometrial cycle is depicted here?" "Early premenstrual phase" "Secretory phase" "Proliferative phase" "Menstrual phase" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2973.jpg" -"2974" "What does the eosinophilic material filling the central crateriform structure represent?" "Necrotic debris" "Keratin material" "Mucin" "Collagen" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2974.jpg" -"2975" "What is the characteristic appearance of the structures identified within the dermal layer?" "Spherical basophilic structures with a homogeneous appearance" "Linear basophilic formations with a stratified structure" "Irregularly shaped with an eosinophilic appearance" "Angular hyperchromatic structures with a heterogeneous appearance" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2975.jpg" -"2976" "What is the likely identity of the irregular clear spaces seen throughout the image?" "Adipose tissue" "Epithelial inclusions" "Areas of necrosis" "Glycogen deposits" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2976.jpg" -"2977" "What feature is predominant in the pinkish-staining areas of the image?" "Mucinous stroma" "Necrotic tissue" "Collagen deposition" "Hyaline cartilage" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2977.jpg" -"2978" "Observing the nuclei of the cells in the image, how would you describe their appearance?" "Small and round with open chromatin" "Large and pleomorphic with prominent nucleoli" "Elongated and hyperchromatic" "Vesicular with a fine chromatin pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2978.jpg" -"2979" "What is the predominant histologic feature observed in the thyroid follicular cells?" "Uniform colloid distribution in the follicles" "Thickened, dense colloid within the follicles" "Hyperplasia of the follicular cells" "Presence of oncocytic changes in epithelial cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2979.jpg" -"2980" "How would you describe the arrangement of the cells in this tissue sample?" "Cells are arranged in a tightly-packed glandular pattern" "Cells are dispersed in an irregular, wavy pattern" "Cells are forming a pseudostratified layer" "Cells are organized in parallel bundles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2980.jpg" -"2981" "What characteristic feature of the extracellular matrix can be observed in this image?" "Concentric rings of calcification" "Abundant and eosinophilic homogenous matrix" "Sparse matrix with high cellularity" "Well-organized and thin collagen fibers" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2981.jpg" -"2982" "What type of tissue architecture predominates the microscopic field?" "Fibrotic tissue completely replacing glandular structures" "Uniform, well-formed glands" "Villous structures with some architectural distortion" "Haphazardly arranged glands" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2982.jpg" -"2983" "Considering the morphology of the tissue, what feature suggests an erosive process?" "Presence of a necrotic debris" "Diminished size and sparse distribution of the glands" "Hyperchromasia of the nuclei" "Thickening of the basement membrane" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2983.jpg" -"2984" "In the skin biopsy image provided, which cell layer appears to have increased nuclear density suggesting a potential neoplastic process?" "Stratum Corneum" "Stratum Spinosum" "Stratum Granulosum" "Stratum Basale" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2984.jpg" -"2985" "What is the predominant cell type seen in the provided tissue section?" "Squamous epithelial cells" "Adipocytes" "Smooth muscle cells" "Hepatocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2985.jpg" -"2986" "What is the predominant type of tissue surrounding the adipocytes within this histologic slide?" "Skeletal muscle tissue" "Hyaline cartilage" "Dense irregular connective tissue" "Loose connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2986.jpg" -"2987" "How would you describe the organization of the follicular structures in the tissue image?" "Uniform with well-defined regular spherical formations" "Disorganized with irregularly shaped formations" "Lined with multiple layers of cells" "Organized with bi-layered cellular organization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2987.jpg" -"2988" "Based on the observed morphologic characteristics, what secretion type is demonstrated by the glandular cells?" "Apocrine secretion" "Holocrine secretion" "Sebaceous secretion" "Merocrine secretion" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2988.jpg" -"2989" "Identify the tissue type found at the bottom of the provided image?" "Adipose tissue" "Hyaline cartilage" "Elastic cartilage" "Fibrocartilage" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2989.jpg" -"2990" "What components can be identified at the points indicated by yellow arrows?" "Hepatocyte cords" "Central veins" "Kupffer cells" "Portal triads" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2990.jpg" -"2991" "What feature of the epidermis can be appreciated in this histologic section?" "Hypergranulosis" "Parakeratosis" "Acantholysis" "A normal stratum corneum" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2991.jpg" -"2992" "Based on the histopathological features seen in this image, what is the condition of the dermis?" "Normal vascularity" "Fibrosis in the reticular dermis" "Melanocytic proliferation" "Edema in the papillary dermis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2992.jpg" -"2993" "Analyzing the dermis, what type of inflammatory cells predominate in this specimen?" "Lymphocytes with occasional eosinophils" "Neutrophils" "Plasma cells" "Macrophages" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2993.jpg" -"2994" "What does the presence of elongated rete ridges in this biopsy most likely suggest?" "Psoriasiform hyperplasia" "Chronic dermatitis" "Bacterial infection" "Acute inflammation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2994.jpg" -"2995" "What additional feature might be present around the granulomas based on the lower staining area?" "Amyloid deposition" "Increased vascularization" "Melanin accumulation" "Mucin deposits" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2995.jpg" -"2996" "Considering the cellular differentiation within the glandular structures observed in the image, which of the following describes the tissue organization?" "Uniform cellular differentiation with abundant stromal tissue" "Lack of cellular differentiation and maturation with nuclei present towards both apical and basal sides" "Presence of well-differentiated cells with nuclei polarized towards the basement membrane" "Goblet cells uniformly distributed along the glandular epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2996.jpg" -"2997" "On assessing the nuclear characteristics of the epithelial cells, which statement is accurate?" "Nuclei are basally located and show uniformity" "Hyperchromatic and pleomorphic nuclei are observed" "A large number of mitotic figures are present" "The nuclei show enlargement and irregular contours" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2997.jpg" -"2998" "What histological feature is absent in this tissue specimen, which can be indicative of certain types of epithelial pathology?" "Hyperchromatic nuclei" "Presence of numerous multinucleated giant cells" "Infiltration of inflammatory cells" "Formation of keratin pearls" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2998.jpg" -"2999" "Based on the cellular arrangement, what is the status of the lumen within the duct-like structure?" "Filled with heterogeneous cell population lacking a lumen" "Narrowed, but with a visible lumen" "Clearly visible and open" "Filled with homogenous cell population" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/2999.jpg" -"3000" "What is the general pattern of cellular organization throughout the depth of the lesion?" "Cells show clear maturation with depth, becoming larger and pleomorphic in the deeper aspects" "Cells exhibit decreased cellularity and increased fibrosis with depth" "The cellular composition seems uniformly dense throughout the depth of the lesion" "There is necrosis and significant inflammation in the deeper aspects of the lesion" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3000.jpg" -"3001" "Considering the degree of cellular infiltration observed among the adipocytes, how would you grade the extent of this infiltration?" "Moderate, with multiple patches of cellularity" "Absent, with complete adipocyte morphology preservation" "Severe, with substantial clusters of inflammatory cells" "Mild, with no significant clusters or sheets of inflammatory cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3001.jpg" -"3002" "Based on the pigmentation observed around the hair follicle, what can be inferred?" "Melanin deposits from a previous anagen phase" "Presence of active melanocytes in the anagen phase" "Extensive pigment production associated with inflammation" "Pigmentation as a result of a disease process" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3002.jpg" -"3003" "Looking at the areas surrounding the large circular clear spaces, how would you best describe the appearance of the nuclei?" "The nuclei are not visible at all" "The nuclei are large with abundant cytoplasm suggestive of macrophages" "The nuclei are small and uniform in size" "The nuclei are elongated or irregularly shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3003.jpg" -"3004" "What feature of the cellular infiltrate most strongly suggests a high-grade malignancy?" "Uniformity and density of the medium-sized cells" "Presence of multinucleated giant cells" "Variation in cell size" "Abundance of cells with cytoplasmic granules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3004.jpg" -"3005" "How would you characterize the staining properties of the tumor cells seen predominantly throughout the image?" "Clear cells with inconspicuous nuclei" "Eosinophilic with peripheral nuclei" "Basophilic with round nuclei" "Amphophilic with spindle-shaped nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3005.jpg" -"3006" "How does the cytoplasm of the acinar cells appear in the microscopic image?" "Pale and clear" "Eosinophilic and granular" "Foamy with vacuolations" "Basophilic with inclusions" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3006.jpg" -"3007" "Based on the cells' morphology in the top layer labeled 'I', what cellular organization do they most likely represent?" "Mature chondrocytes in lacunae of cartilage" "Epithelial cells in a stratified arrangement" "Fibroblasts in loose connective tissue" "Adipocytes within adipose tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3007.jpg" -"3008" "What does the bottom region of the tissue characterized by increased vascularity and cellularity with less organized extracellular matrix suggest?" "Early stages of bone formation" "Active inflammatory response" "Ongoing muscle regeneration" "Necrotic tissue undergoing phagocytosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3008.jpg" -"3009" "Focusing on the interface with underlying tissue in the image, what does the pattern of cellularity suggest about the relationship between the infiltrating cells and the more structured area?" "The infiltrating cells are smoothly demarcated from the structured tissue without intermingling" "The infiltrating cells and the structured tissue demonstrate a transitional blending pattern" "The infiltrating cells are displacing the structured tissue in a benign expansion pattern" "The infiltrating cells are irregularly invading the structured tissue with a pushing border" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3009.jpg" -"3010" "Based on the cytomorphologic features observed in the image, which of the following best describes the nuclear characteristics of the densely cellular field?" "Hypochromatic and pleomorphic nuclei" "Hyperchromatic and pleomorphic nuclei" "Finely dispersed chromatin in round to ovoid nuclei" "Hyperchromatic and monomorphic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3010.jpg" -"3011" "Analyze the organization of cells seen in the image. What can you infer regarding the cellular arrangement?" "Cells are arranged in a haphazard manner without distinct polarity" "Cells are spindle-shaped and arranged in interweaving fascicles" "Cells exhibit extensive pleomorphism and varied orientation" "Cells display consistent polarity and are arranged in an organized epithelial layer" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3011.jpg" -"3012" "Based on the cellular details observed in the image, how would you describe the nuclei of the glandular epithelial cells?" "Multiple and irregularly shaped" "Enlarged with prominent nucleoli" "Hyperchromatic and pleomorphic" "Basally located with uniform size" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3012.jpg" -"3013" "How would you describe the appearance of the nuclei of the glandular cells?" "Enlarged with prominent nucleoli" "Small and hyperchromatic with frequent mitotic figures" "Markedly pleomorphic with significant atypia" "Small and uniform" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3013.jpg" -"3014" "What does the peripheral location of the cell nuclei indicate in these hepatocytes?" "Alcoholic hepatitis" "Lysosomal storage disease" "Viral hepatitis" "Hepatocellular carcinoma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3014.jpg" -"3015" "How would you describe the arrangement of the nuclei within the tissue fragments in this image?" "Singly isolated" "Loosely dispersed" "Densely arranged" "Forming glandular structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3015.jpg" -"3016" "What is the nature of the connective tissue material observed in the surrounding stroma?" "Myxoid" "Necrotic" "Basophilic" "Eosinophilic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3016.jpg" -"3017" "Based on the appearance of the cytoplasm, how can the majority of cells in this image be characterized?" "The cytoplasm appears mostly vacuolated" "The cytoplasm is predominantly eosinophilic" "The cytoplasm has a highly granular texture" "The cytoplasm shows evidence of significant lipid accumulation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3017.jpg" -"3018" "Judging by the background matrix, could you identify the likely tissue type represented in this microscopic image?" "Fibrillary matrix consistent with glial tissue" "Loose areolar connective tissue" "Hyaline cartilage" "Dense irregular connective tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3018.jpg" -"3019" "What do the concentric patterns and smooth appearance in the pink-stained areas most closely represent?" "Adipose tissue" "Muscle tissue" "Bone tissue" "Neural tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3019.jpg" -"3020" "In assessing the stroma surrounding the neoplastic cells, what feature is indicative of a seminoma?" "Abundant hemosiderin deposits" "Extensive necrosis" "Dense lymphocytic infiltration" "Mild fibrosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3020.jpg" -"3021" "The erythrocytes in this image most commonly exhibit which of the following size-related characteristics?" "Normocytosis" "Anisocytosis" "Microcytosis" "Macrocytosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3021.jpg" -"3022" "Which type of inflammatory cell predominates in the mixed inflammatory infiltrate visible in this histologic section?" "Plasma cells" "Eosinophils" "Neutrophils" "Lymphocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3022.jpg" -"3023" "Based on nuclear features, what is the most likely characteristic of the cells observed in this image?" "Lack of prominent nucleoli" "Uniformity in nuclear size and shape" "Presence of anisokaryosis" "Monotonous population of nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3023.jpg" -"3024" "What does the presence of scattered lighter areas within the densely cellular tissue most likely represent?" "Cartilaginous matrix" "Mucin deposition" "Areas of necrosis or fibrosis" "Fatty infiltration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3024.jpg" -"3025" "Based on the morphology and abundance of cytoplasm, which cell type predominates in this microscopic view?" "Lymphocytes" "Erythrocytes" "Neutrophils" "Eosinophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3025.jpg" -"3026" "Regarding the general cellular arrangement, what can be said about the tissue structure?" "The arrangement includes rosette formation" "Cells exhibit a significant degree of spindle shape" "There is a high level of nuclear crowding and overlapping" "Cells display a syncytial growth pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3026.jpg" -"3027" "Looking at the ductal spaces involved, how would you characterize the extent of involvement?" "The involvement of ductal spaces is monomorphic with complete loss of luminal space." "There are multiple, variably-sized ductal spaces involved with preserved architecture." "All ductal spaces are completely filled with high-grade atypical cells, indicating invasive growth." "The ductal involvement is extensive throughout the tissue, lacking any normal architecture." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3027.jpg" -"3028" "Based on the morphology of the nuclei visible in the image, what type of cell is primarily featured?" "Chondrocytes with round and lacunar nuclei" "Schwann cells with elongated, wavy nuclei" "Fibroblasts with spindle-shaped nuclei" "Osteocytes with dense and irregular nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3028.jpg" -"3029" "What does the eosinophilic matrix surrounding the cells suggest about the type of tissue present?" "Presence of abundant keratinized tissue" "Presence of dense connective tissue rich in collagen" "Presence of highly cellular adipose tissue" "Presence of hyaline cartilage with abundant proteoglycans" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3029.jpg" -"3030" "Which feature in this image is most indicative of a potential chronic inflammatory condition?" "Density of the collagen fibers" "Uniform thickness of collagen fibers" "Presence of cells with larger nuclei and minimal cytoplasm" "Sparse distribution of cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3030.jpg" -"3031" "What is the morphology of the cells lining the blood-filled spaces?" "Well-differentiated cells with abundant cytoplasm" "Uniform polygonal cells with small, round nuclei" "Monotonous small cells with hyperchromatic nuclei" "Atypical cells with variation in size and shape" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3031.jpg" -"3032" "Based on the nuclear characteristics, what is the predominant nuclear feature of the cells within the densely cellular tissue?" "Monomorphic nuclei with regular contours" "Uniform nuclei with prominent nucleoli" "Anisonucleosis with hyperchromatic nuclei" "Small, hyperchromatic nuclei with scant cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3032.jpg" -"3033" "Based on the hepatocytes visible in the image, what is the predominant alteration observed?" "Numerous eosinophilic inclusions" "Predominance of lymphocytic infiltration" "Extensive granulomatous inflammation" "Widespread ballooning degeneration" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3033.jpg" -"3034" "Based on the morphological features observed in the image, which type of inflammatory cells predominates in the infiltrate?" "Eosinophils" "Neutrophils" "Macrophages" "Plasma cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3034.jpg" -"3035" "Based on the microscopic appearance, which feature differentiates the lesion in this image from seborrheic keratosis?" "Dermal nevus cells" "Horn pseudocysts" "Nesting of melanocytes" "Elongated rete ridges and papillomatosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3035.jpg" -"3036" "Identify the type of tissue that appears to be primarily affected by the embedded tick based on the histological characteristics seen in the image." "Skeletal muscle" "Adipose tissue" "Connective tissue" "Nervous tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3036.jpg" -"3037" "Based on the microscopic features observed in the image, what type of inflammatory response is most likely associated with the embedded structure?" "Chronic fibrosing inflammation" "Acute serous inflammation" "Acute suppurative inflammation" "Chronic granulomatous inflammation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3037.jpg" -"3038" "What is the nature of the cytoplasm and nuclei of the cells based on the staining properties seen in this image?" "Cytoplasm appears basophilic and nuclei appear eosinophilic" "Cytoplasm appears eosinophilic and nuclei appear basophilic" "Both cytoplasm and nuclei appear basophilic" "Both cytoplasm and nuclei appear eosinophilic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3038.jpg" -"3039" "Based on the microscopic features observed in the image, which of the following best describes the appearance of the nuclei within the glands?" "Pleomorphic nuclei with prominent nucleoli" "Small, hyperchromatic nuclei with no visible nucleoli" "Round nuclei with multiple small nucleoli" "Uniform nuclei with inconspicuous nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3039.jpg" -"3040" "Based on the organization of the cells and the density of the fibrous stromal tissue, which pathology is most consistent with the features shown in the image?" "Adenocarcinoma" "High-grade sarcoma" "Lymphoma" "Highly cellular fibroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3040.jpg" -"3041" "Looking at the microscopic view of the tissue, which indication of pathology can be suggested based on the disordered tissue architecture and variations in cell size and organization?" "Acantholysis" "Hyperkeratosis" "Dyskeratosis" "Epidermolytic acanthoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3041.jpg" -"3042" "What is the likely nature of the rounded to oval structures interspersed within the connective tissue?" "Muscle fibers" "Blood vessels" "Glands or follicles" "Nerve bundles" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3042.jpg" -"3043" "What morphological feature of cellular degeneration is evident in this microscopic image?" "Cytolysis" "Karyorrhexis" "Karyolysis" "Anaplasia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3043.jpg" -"3044" "What is the characteristic feature observed in the nuclei of numerous cells within this tissue section?" "Binucleation" "Pyknotic nuclei" "Prominent nucleoli" "Multinucleation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3044.jpg" -"3045" "In evaluating the lighter-stained clusters of cells that stand out in the background, what is the most likely composition of these clusters based on their distinct staining and structural characteristics?" "Acinar cells packed densely with zymogen granules" "Endocrine cells forming the islets of Langerhans" "Fibroblasts forming a connective tissue matrix" "Adipocytes with large lipid vacuoles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3045.jpg" -"3046" "In the context of organ identification, what distinguishing features are observable in the tissue section?" "Villi and crypts characteristic of intestinal mucosa" "Purkinje fibers indicating cardiac tissue" "Well-delineated clusters suggesting islets of Langerhans" "Hepatic sinusoids typically found in liver tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3046.jpg" -"3047" "In the provided microscopic image of the tissue, how would you characterize the distribution of nuclei within the cells?" "Monomorphic and hypochromatic" "Pleomorphic and hyperchromatic" "Anisonucleosis with prominent nucleoli" "Monomorphic and relatively hyperchromatic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3047.jpg" -"3048" "Based on the presence of cellular and structural features in the image, what is the most likely histological diagnosis?" "Normal glandular tissue" "Squamous cell carcinoma" "Adenocarcinoma" "Adenoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3048.jpg" -"3049" "Based on the cellular morphology, what is the most likely characteristic of the dermo-epidermal junction in this image?" "Papillomatosis with hyperkeratosis" "Presence of extensive rete ridges" "Smooth and straight appearance" "Acantholysis with blister formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3049.jpg" -"3050" "What feature of the dermis can be deduced from this histological image?" "Well-defined rete ridges and papillary structures" "Normal fibrous texture and coloration" "Dense inflammatory infiltrate throughout the dermis" "Area of hyalinized collagen indicating sclerotic process" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3050.jpg" -"3051" "Evaluating the proportion of CD45 stained cells to unstained cells, which type of cells appears to be dominant within this tissue section?" "Cells negative for CD45 antigen are scarcely present." "CD45 positive lymphoid cells are the dominant population." "An almost equal proportion of CD45 positive and negative cells." "CD45 negative cells constitute the dominant cell population." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3051.jpg" -"3052" "What does the morphology of the cells below the surface layer suggest about the type of epithelium shown in the image?" "Pseudostratified columnar with cells appearing to be in a single layer but actually stratified" "Stratified transitional with multiple layers of varied cell shapes" "Simple squamous due to a single layer of flattened cells" "Stratified squamous with layers of flattened cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3052.jpg" -"3053" "What kind of pattern is observed in the epidermal layer with regards to the distribution of the CD3-positive T-cells?" "Diffuse throughout the epidermis" "Discontinuous clusters" "Tagging along the basal layer" "Randomly scattered" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3053.jpg" -"3054" "What cytoplasmic characteristic is predominantly observed in the cells within this microscopic image?" "Pale cytoplasm with prominent clearing" "Eosinophilic cytoplasm that is densely stained" "Cytoplasm with numerous granules" "Darkly stained cytoplasm with no clear boundaries" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3054.jpg" -"3055" "What characteristic feature of the superficial layers of the stratified squamous epithelium can be observed in this image?" "Superficial cells have undergone keratinization" "Presence of prominent intercellular bridges" "Nuclei are still visible in superficial cells" "Multinucleated giant cells are present" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3055.jpg" -"3056" "In the context of the described pathology, which structures among the following can be identified within the keratinized layers of the epithelium?" "Refractile yeast forms and filamentous hyphae" "Large irregular nucleated squamous cells" "Eosinophilic granular bodies" "Melanocytic nevi" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3056.jpg" -"3057" "What best describes the arrangement of the spindle cells seen in this tissue section?" "Arranged in well-formed vascular channels" "Haphazard arrangement without a definite pattern" "Organized in a well-defined whorled pattern" "Uniformly arranged with consistent cell orientation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3057.jpg" -"3058" "What cellular feature is indicated by brownish pigment scattered throughout the spindle cell proliferation?" "Lipofuscin accumulation" "Hemosiderin deposition" "Necrosis" "Keratin deposition" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3058.jpg" -"3059" "What is the predominant pattern of cell arrangement observed in this image?" "Round cells forming gland-like structures" "Cuboidal cells lining well-formed ducts" "Spindle-shaped cells in a patternless architecture" "Large multinucleated giant cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3059.jpg" -"3060" "Based on the morphology of the cells observed in the image, which cytological feature is predominantly exhibited?" "Multinucleated giant cells" "Dyskeratotic cells" "Spindle-shaped cells" "Signet ring cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3060.jpg" -"3061" "What does the presence of yellowish-brown pigmented areas in the image most likely represent?" "Hemosiderin deposition" "Glycogen accumulation" "Lipofuscin accumulation" "Melanin deposition" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3061.jpg" -"3062" "Taking into consideration the provided image, which statement correctly describes the staining technique likely used?" "Masson's trichrome staining connective tissue" "Hematoxylin and eosin staining nuclear and cytoplasmic features" "Wright's stain for hematopoietic cells" "Periodic acid-Schiff highlighting glycogen" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3062.jpg" -"3063" "Regarding the lesion's cellular morphology, which of the following features of the nuclei can be observed in the melanocytic cells within the dermis?" "Uniform, hypochromatic nuclei with inconspicuous nucleoli" "Large, pale nuclei with prominent nucleoli" "Small, hyperchromatic nuclei with conspicuous nucleoli" "Hyperchromatic nuclei with irregular borders" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3063.jpg" -"3064" "When assessing the epidermal-dermal interface in this image, what feature can be noted?" "Presence of normal rete ridges" "A clear Grenz zone" "Preservation of the dermal papillae" "Confluence of melanocytic nests with the epidermis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3064.jpg" -"3065" "Based on the morphology of the cells within the outlined area, what is the most likely architectural feature of the tissue?" "Well-differentiated with regular architecture" "Dysplastic with slight disturbance in normal architecture" "Hyperplastic with preserved tissue architecture" "Anaplastic with loss of normal architecture" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3065.jpg" -"3066" "How would you describe the presence and appearance of nucleoli within the nuclei of the outlined cells?" "Single and prominent nucleoli" "Small and inconspicuous nucleoli" "Invisible nucleoli" "Prominent and multiple nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3066.jpg" -"3067" "Which description best matches the appearance of the cells that line the cystic structures?" "Flattened or attenuated epithelial-like cells" "Small round cells with hyperchromatic nuclei" "Multinucleated giant cells with copious cytoplasm" "Tall columnar with abundant eosinophilic cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3067.jpg" -"3068" "Based on the properties of the structures resembling cocci bacteria, what staining method might have been used for this tissue section?" "Gram stain" "Periodic acid-Schiff stain" "Hematoxylin and eosin stain" "Acid-fast stain" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3068.jpg" -"3069" "In the image, what is the significance of observing squamous eddies or whorls within the epithelial tissue?" "They suggest the presence of a benign neoplasm" "They are characteristic of an acute inflammatory process" "They are indicative of reactive hyperplasia due to irritation" "They denote areas of increased mitotic activity" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3069.jpg" -"3070" "Based on the irregular blue-gray areas observed in the microscopic image, what pathological process might be occurring in the tissue?" "Lipid accumulation" "Amyloidosis" "Hyaline degeneration" "Mineralization or ossification" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3070.jpg" -"3071" "Focusing on the relation between the stratified squamous epithelium and the neighboring disorganized tissue mass, what is apparent at their interface?" "A disordered intersection where the disarray extends toward the epithelium" "A gradual blending with extensive stromal interaction" "An abrupt transition with a clear line of demarcation" "A regeneration of normal epithelium overlying the disorganized tissue mass" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3071.jpg" -"3072" "The transition zone near the edge of the image indicated by the yellow arrow would most likely lead into which additional neural structure?" "Ventricular system" "Meninges" "Adjoining gray matter" "Neighboring neural tissue from another segment of the spinal column" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3072.jpg" -"3073" "Considering the histopathological characteristics visible in the image, which of the following best describes the appearance of the concentrically layered structures?" "Aschoff bodies" "Keratin pearls" "Psammoma bodies" "Russell bodies" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3073.jpg" -"3074" "Considering the appearance of the stroma surrounding the glands, which description is accurate?" "There is significant cellular overcrowding and pleomorphism." "The stroma contains an ordered distribution of nuclei with no marked cellular density." "A substantial amount of dysplastic cells are present within the stroma." "The stromal tissue shows extensive fibrosis and lack of cellular elements." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3074.jpg" -"3075" "Based on the organization of the cells, what type of growth pattern seems to be indicated in this tissue section?" "Lobular arrangement typical of functional secretory tissue" "Organized, with clear glandular differentiation" "Disorganized, infiltrative growth pattern lacking normal structure" "Regular, polarized epithelial cell arrangement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3075.jpg" -"3076" "Identify the type of fibrous structure present in the stroma as seen in this microscopic image of the tissue." "Pink fibrillar material possibly representing smooth muscle fibers or fibrotic bands" "Basophilic cartilaginous matrix" "Long, thin red blood cells" "Thick, pink-stained collagen bundles" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3076.jpg" -"3077" "In the large mature Graafian follicle visible in this histologic section of the ovary, what structure can be identified at its periphery?" "Theca interna" "Granulosa cell layer" "Corona radiata" "Oocyte" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3077.jpg" -"3078" "Examining the region above the pigmented layer, what is the general appearance of the extracellular space most reminiscent of?" "Loose connective tissue with abundant ground substance" "Thick hyalinized collagen bundles" "Highly vascular connective tissue" "Fibrillar, less cellular appearance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3078.jpg" -"3079" "Focusing on the topmost layer of tissue in the image, what cell feature is most prominent?" "Uniform small-sized cells with minimal cytoplasm" "High amount of extracellular matrix" "Dense connective tissue fibers" "Cells varying in size with prominent nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3079.jpg" -"3080" "Focusing on the stromal characteristics surrounding the clusters of atypical cells in this image, which feature is predominantly observed?" "Mature adipose tissue" "Hyalinized stroma with little to no inflammatory response" "Fibrous stroma with a reactive inflammatory cell infiltrate" "Myxoid matrix with loose connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3080.jpg" -"3081" "Based on the arrangement of the nuclei in this tissue, which pattern is most evident?" "Rosette pattern" "Storiform pattern" "Alveolar pattern" "Fascicular pattern" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3081.jpg" -"3082" "Based on the cellular infiltration observed at the basal portion of the mucosa, which cell type is prominently increased in this sample?" "Neutrophils" "Lymphocytes" "Plasma cells" "Eosinophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3082.jpg" -"3083" "What pathological process is suggested by the presence of basal plasmacytosis in conjunction with the observed crypt abnormalities?" "Acute infection" "Chronic inflammation" "Neoplastic transformation" "Ischemic injury" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3083.jpg" -"3084" "What characteristic morphology is exhibited by the large cells within the granuloma?" "A single, central round nucleus" "Multiple nuclei arranged in a horseshoe pattern" "Multiple small, darkly stained nuclei scattered throughout the cytoplasm" "A single, elongated nucleus across the cell" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3084.jpg" -"3085" "How would you describe the cytoplasm of the epithelioid histiocytes observed in the granuloma?" "Basophilic with multiple vacuoles" "Eosinophilic without granules" "Eosinophilic with numerous granules" "Amphophilic with scribbled inclusions" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3085.jpg" -"3086" "What does the presence of central, round nuclei within the hepatocytes in the image suggest about the cells' activity?" "They are in a state of necrosis" "They are undergoing rapid mitosis" "They are in a state of hypertrophy" "They are in a state of normal activity" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3086.jpg" -"3087" "Observing the nuclei at the location indicated by arrow 'c', what can we infer about the polarity of the cells?" "The cells exhibit apical polarity" "The cells exhibit basal polarity" "The cells exhibit multipolar characteristics" "The cells are non-polar" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3087.jpg" -"3088" "Based on the cellular arrangement and features, which of the following best describes the tissue type at the lower part of the image around label 'b'?" "Stratified squamous epithelium" "Transitional epithelium" "Ciliated pseudostratified columnar epithelium" "Simple columnar epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3088.jpg" -"3089" "What is the diagnostic significance of the multinucleated giant cells observed in the tissue?" "Associated with pleomorphic lipoma" "Indicative of embryonal carcinoma" "Typical of adenocarcinoma" "Suggestive of osteosarcoma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3089.jpg" -"3090" "What histological feature is evident at the center of this skin biopsy?" "Hypergranulosis" "Acantholysis" "Parakeratosis" "Spongiosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3090.jpg" -"3091" "What do the round, eosinophilic bodies within the epidermis represent?" "Corps ronds" "Langerhans cells" "Melanocytes" "Keratohyalin granules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3091.jpg" -"3092" "Based on the histological features observed, what type of cells predominantly surround the adipocytes?" "Fibroblasts with an elongated shape" "Macrophages with an irregular cell boundary" "Endothelial cells lining blood vessels" "T cells with a high nuclear to cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3092.jpg" -"3093" "What does the presence of brown staining cells around the adipose tissue suggest?" "Accumulation of hemosiderin-laden macrophages" "Positive staining for a T-cell marker indicating lymphocytic infiltration" "Melanin production within the cells" "Abundance of iron deposits within the tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3093.jpg" -"3094" "Based on the observed characteristics of the tissue, which type of connective tissue is depicted in this microscopic view?" "Loose connective tissue" "Adipose tissue" "Dense irregular connective tissue" "Dense regular connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3094.jpg" -"3095" "Considering the connective tissue reaction to the atypical cell proliferation, which characteristic is evident in this microscopic view?" "Extensive mucinous degeneration" "Dense collagenous stroma" "Hyalinization of the stromal components" "Predominance of adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3095.jpg" -"3096" "When assessing the blood vessels in the image, what pathological feature is evident?" "Arteriosclerotic vessel wall thickening" "Dilated blood vessels with red blood cells in their lumina" "Thrombosis within the vessel lumina" "Vasculitis with fibrinoid necrosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3096.jpg" -"3097" "What histological feature is predominantly observed in this image of lymph node tissue?" "Necrosis" "Granulomas" "Neoplastic cells" "Anthracotic pigment" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3097.jpg" -"3098" "Based on cellular organization and morphology, what type of epithelium is demonstrated in this microscopic image?" "Simple squamous epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "Stratified squamous epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3098.jpg" -"3099" "What property of the epithelium in this image indicates that it is non-keratinized?" "Presence of a granular layer" "Multinucleate cell appearance" "Cells with a pale cytoplasm" "Uppermost cells with darkly stained cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3099.jpg" -"3100" "Based on the histological features observed, how would the differentiation status of this pancreatic tissue be classified?" "Moderately differentiated" "Well-differentiated" "Anaplastic" "Poorly differentiated" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3100.jpg" -"3101" "What assessment can be made about the cellular architecture within the well-delineated areas in the right portion of the image?" "The cells are arranged in a disorganized manner, supportive of a dysplastic process." "The cells have a uniform shape and size, indicative of a benign process." "There is a presence of multi-nucleated giant cells, suggestive of granulomatous inflammation." "The cells display varying shapes and sizes, which is a characteristic commonly associated with neoplastic processes." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3101.jpg" -"3102" "Based on the histological features, which of the following options correctly describes the cells' nuclei?" "Small, round blue nuclei with prominent nucleoli" "Elongated, serpentine nuclei with open chromatin" "Hyperchromatic and pleomorphic nuclei" "Large vesicular nuclei with multiple nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3102.jpg" -"3103" "What does the matrix surrounding the cells in this histological section predominantly indicate?" "Eosinophilic, collagen-rich matrix" "Dense fibrous connective tissue" "Myxoid matrix with loose arrangement" "Hyalinized stroma with calcifications" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3103.jpg" -"3104" "What is the predominant cell type visible in the microscopic image of the tissue?" "Spindle-shaped mesenchymal cells" "Cuboidal epithelial cells" "Squamous epithelial cells" "Columnar epithelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3104.jpg" -"3105" "Which description fits the cellular organization of the tissue?" "Disorganized with moderate cell variation" "Organized with significant pleomorphism" "Highly cellular with marked inflammatory infiltrate" "Highly organized with uniform cell distribution" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3105.jpg" -"3106" "What feature of the stratum corneum is most evident when examining the epidermal layer?" "Absence of the stratum corneum" "Thinning of the stratum corneum" "Normal, organized layering" "Thickened and disorganized appearance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3106.jpg" -"3107" "Assessing the overall morphology and cellular features seen in the image, what is the most likely lesion type?" "Benign papillary lesion" "High-grade carcinoma" "Dysplastic adenoma" "Inflammatory infiltrate" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3107.jpg" -"3108" "Observing the glandular structures in the provided microscopic image, which feature is indicative of possible malignancy?" "Glandular structures with cystically dilated formations" "Small, closely packed glands with dense fibrous stroma" "Evenly distributed glands with a smooth stromal interface" "Uniformly sized glands with regular borders" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3108.jpg" -"3109" "Based on the histological features observed, which characteristic best describes the nuclei of the cells lining the glandular structures?" "Hyperchromatic with variation in size" "Small and pyknotic" "Uniformly small with homogenous chromatin" "Vesicular with prominent nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3109.jpg" -"3110" "Based on the examination of the epidermal layer, what histopathological feature is most prominent?" "Acantholysis" "Hyperplasia" "Parakeratosis" "Hyperkeratosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3110.jpg" -"3111" "Considering the staining characteristics, what can be inferred about the nature of the extracellular matrix?" "Extensive calcification" "Abundant mucinous material" "Predominantly hyaline cartilaginous matrix" "Moderate amount of collagenous matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3111.jpg" -"3112" "What pattern predominates in the ductal cell arrangement of this breast tissue?" "Cribriform" "Solid" "Micropapillary" "Papillary" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3112.jpg" -"3113" "What cellular morphology can be identified in the background of the image?" "Cells with large, pale staining nuclei" "Large cells with a high nucleocytoplasmic ratio" "Cells exhibiting hypereosinophilic cytoplasm" "Cells with smaller, densely stained granules" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3113.jpg" -"3114" "What feature is lacking on the surface epithelium of this gastric mucosa?" "Erosion of the superficial mucosal layer" "Hyperplastic goblet cells" "Parakeratosis" "Presence of foveolar cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3114.jpg" -"3115" "Are there any signs of active inflammation with abundant neutrophils present in the image?" "Yes, there are abundant neutrophils indicating active inflammation" "No, there is no inflammation at all" "No, there are no neutrophils but signs of chronic inflammation are present" "Yes, but neutrophils are sparse and do not indicate significant active inflammation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3115.jpg" -"3116" "What best describes the arrangement of the nuclei in the cells of the uppermost layer of the tissue section?" "The nuclei are elongated and appear arranged in a linear fashion." "The nuclei are large with prominent nucleoli." "The nuclei are round and exhibit a disorganized arrangement." "The nuclei are small and hyperchromatic." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3116.jpg" -"3117" "Based on the observable features, how is the extracellular matrix in the tissue section predominantly stained?" "The extracellular matrix is primarily stained blue." "The extracellular matrix is predominantly stained pink." "The extracellular matrix is unstained and appears clear." "The extracellular matrix shows a multicolored pattern." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3117.jpg" -"3118" "What is the morphology of the epithelial cells lining the tubular structures in this microscopic image?" "Squamous" "Cuboidal" "Columnar" "Transitional" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3118.jpg" -"3119" "What cell morphology predominates in this microscopic image?" "Anaplastic cells with no distinctive shape" "Polygonal cells with discrete cytoplasmic boundaries" "Round cells with abundant cytoplasm" "Elongated, spindled cells with thin cytoplasmic processes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3119.jpg" -"3120" "What immunohistochemical marker can be inferred to have been used to highlight the atypical lymphoid cells in this tissue sample?" "CD20 marker indicating B-cell lineage" "Melan-A marker specific for melanocytes" "CD3 marker denoting T-cell lineage" "CD68 marker highlighting macrophage presence" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3120.jpg" -"3121" "Identify the epidermal layer that shows bluish staining and cells with larger, rounder nuclei positioned just beneath the stratum corneum." "Stratum lucidum" "Stratum spinosum" "Stratum basale" "Stratum granulosum" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3121.jpg" -"3122" "Based on the arrangement of spindle cells in the image, which pattern would you primarily associate with the observed tissue morphology?" "Alveolar pattern" "Palisading pattern" "Herringbone pattern" "Whorled pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3122.jpg" -"3123" "What morphological feature can be seen in the nuclei of some of the cells within the image?" "Uniformly round and small nuclei" "Multiple nucleoli within nuclei" "Binucleated cells" "Pyknotic nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3123.jpg" -"3124" "Regarding the distribution and architecture of the cells in the image, what feature is prominently observed?" "Segregation of cells into well-defined lobules" "Presence of regular rosette formations" "Areas of cellular clearing with disrupted architecture" "Homogeneous distribution of cells without clear spaces" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3124.jpg" -"3125" "Based on the cellular morphology observed in the image, which description best fits the texture of the liver parenchyma?" "Smooth and homogenous" "Vacuolated with clear spaces" "Granular and eosinophilic" "Clear and hyaline" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3125.jpg" -"3126" "What is the most likely identity of the spaces between the cords of hepatocytes observed in the image?" "Glycogen deposits" "Sinusoidal capillaries" "Fat droplets" "Bile canaliculi" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3126.jpg" -"3127" "What type of cellular arrangement is shown in the structures that contain cells with uniform, dark-staining nuclei?" "Disorganized clusters of cells" "Single layer of cells around a central lumen" "Structured pattern reminiscent of tubules" "Multiple layers of cells without a lumen" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3127.jpg" -"3128" "When evaluating the architectural pattern of the cells in this tissue section, what pattern can be primarily observed?" "Papillary configuration" "Alveolar-like nesting" "Tubular formation" "Sheet-like proliferation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3128.jpg" -"3129" "On microscopic examination, the presence of which feature is NOT indicative of an overtly malignant process in this tissue section?" "Limited nuclear atypia" "Uniform nuclei size" "Presence of significant pleomorphism" "Invasive growth" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3129.jpg" -"3130" "How do cells near the outer edge of the stratified tissue appear in relation to staining?" "Lightly eosinophilic" "Pale with no distinct staining" "Dense and dark purple" "Bright red" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3130.jpg" -"3131" "Based on the stromal content surrounding the glandular structures, how would you classify the inflammatory response?" "The stroma contains dense collections of lymphocytes indicative of chronic inflammation" "There is presence of scattered inflammatory cells without signs of significant acute inflammation" "The stroma is heavily infiltrated by eosinophils, indicating an allergic inflammatory process" "There is a significant acute inflammatory response with numerous neutrophils present" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3131.jpg" -"3132" "Which component of the spleen is likely represented by the supportive stromal framework and blood vessels present in the image?" "Red pulp" "Trabeculae" "White pulp" "Capsule of the spleen" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3132.jpg" -"3133" "Based on the cellular morphology observed in the image, which cell type found in the spleen appears to be increased?" "Pancreatic acini" "Neutrophils" "Megakaryocytes" "Hepatocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3133.jpg" -"3134" "What characteristic feature of the white blood cells observable in this histological sample provides a clue to their type?" "Bilobed nuclei with granular eosinophilic cytoplasm" "Multilobed nuclei with neutrophilic granules" "Mononuclear shape with basophilic granules" "Large irregular nuclei with sparse cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3134.jpg" -"3135" "Based on the histological features observed, which pathological process is most likely represented in this sample?" "Acute bacterial infection" "Chronic viral infection" "Eosinophilic infiltration and degranulation" "Lymphocytic infiltration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3135.jpg" -"3136" "What is the predominant cell type visible at the surface of this epithelial tissue?" "Squamous cells" "Columnar cells" "Ciliated cells" "Transitional cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3136.jpg" -"3137" "What feature can be observed among the elongated cells at the surface epithelium?" "Keratinization" "Brush border" "Lamina propria" "Neuroendocrine granules" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3137.jpg" -"3138" "What type of glands does the tissue architecture predominantly feature?" "Vesicular glands with dilated lumens indicative of thyroid tissue" "Tubular glands with a central lumen suggesting intestinal crypts" "Sebaceous glands with lipid-filled cells common in skin" "Acinar glands with branched ducts typical of exocrine pancreas" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3138.jpg" -"3139" "Based on the image, what is the evident cytoplasmic characteristic of the cells?" "Abundant and intensely eosinophilic" "Granular with basophilic stippling" "Lightly stained and not highly abundant" "Vacuolated with multiple inclusions" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3139.jpg" -"3140" "What is the predominant feature of the cells at the location indicated by the yellow arrow in the image?" "Smaller cells with dark, dense nuclei" "Cells with eosinophilic cytoplasm and distinct cell borders" "Large cells with abundant cytoplasm" "Large cells with vesicular nuclei and prominent nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3140.jpg" -"3141" "Given the tissue morphology observed, what is the likely function of the lighter-staining areas in the center of the image?" "Production of mucus" "Gas exchange" "Proliferation and differentiation of lymphocytes" "Engulfment and phagocytosis of pathogens" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3141.jpg" -"3142" "Based on the spindle-shaped cellular morphology observed in the tissue sample, which of the following characteristics are present?" "Scattered mitotic figures" "Multinucleated giant cells" "Marked lymphocytic infiltration" "Abundant eosinophilic cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3142.jpg" -"3143" "What type of inflammatory cells are most prevalent within the blister cavity of this histological section?" "Eosinophils" "Neutrophils" "Lymphocytes" "Macrophages" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3143.jpg" -"3144" "How do the collagen fibers in the dermal layer beneath the blister appear in this image?" "Normal in arrangement" "Hyperplastic and disorganized" "Atrophic and thinned" "Swollen and fragmented" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3144.jpg" -"3145" "Based on the histological features, which of the following cellular changes are most evident at the dermal-epidermal junction?" "Hyperkeratosis" "Acanthosis" "Vacuolar alteration" "Parakeratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3145.jpg" -"3146" "What feature of the epidermis can be observed in the histological section?" "A clear stratum corneum as the most superficial layer" "Absence of the stratum basale at the bottom layer" "Stratum granulosum exhibiting prominent granules" "Thickened stratum spinosum" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3146.jpg" -"3147" "What histological feature is prominent within the connective tissue layer below the epithelium?" "Dense cellular infiltrate" "Presence of numerous adipocytes" "Homogeneous extracellular matrix" "Sparse cellular distribution" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3147.jpg" -"3148" "What can be inferred about the region with lighter staining within the blue-outlined area?" "The region is indicative of more aggressive tumor behavior" "The cells in this region are in a state of quiescence" "The region is associated with increased angiogenesis" "The region represents increased apoptotic activity" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3148.jpg" -"3149" "What can be inferred about the specialization or content towards the apical surface of the epithelial cells?" "Less dense staining suggesting some specialization or content" "Presence of cilia for movement" "Presence of darker-stained granules, likely indicating secretory vesicles" "Presence of heavy staining, indicating high concentration of cytoplasmic components" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3149.jpg" -"3150" "Based on the organization of the underlying tissue, how is the muscle layer described in comparison to the epithelial layer?" "Solely composed of circular smooth muscle fibers" "Relatively less organized" "Equally organized and parallel to the epithelial cells" "More organized with striated patterns" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3150.jpg" -"3151" "Considering the cytoplasmic features seen in this microscopic image, what is the most likely appearance of the cells?" "Cytoplasmic granularity suggests oncocytic change" "There is abundant eosinophilic cytoplasm" "The cells display clear, vacuolated cytoplasm" "The cytoplasm appears scant and hyperbasophilic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3151.jpg" -"3152" "What does the transition area to the right of the image represent?" "Dense hyaline matrix" "Cartilage" "Hepatic parenchyma" "Adipose tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3152.jpg" -"3153" "What type of tissue is primarily observed on the left side of this microscopic image?" "Lymphoid aggregate" "Smooth muscle tissue" "Dense irregular connective tissue" "Squamous epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3153.jpg" -"3154" "What is the predominant epithelial lining pattern observed in the glandular structures of this tissue section?" "Pseudostratified columnar epithelium" "Simple columnar epithelium" "Stratified epithelium" "Simple squamous epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3154.jpg" -"3155" "Considering the structural variation within the glands, which glandular shape predominates in this image?" "Tubular with frequent branching" "Irregular and highly complex" "Rounded and cystic" "Vellus-like and generally round" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3155.jpg" -"3156" "In the connective tissue underlying the epithelium, what structures are identifiable?" "Skeletal muscle fibers with striations" "Elongated structures resembling blood vessels" "Adipose cells with large vacuoles" "Osteocytes within a calcified matrix" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3156.jpg" -"3157" "What is the predominant feature of the trophoblastic cells lining the vesicles in the image?" "Spindle-shaped cells with ample eosinophilic cytoplasm" "Single-layered columnar cells with basophilic cytoplasm" "Mononucleated cells with hyperchromatic nuclei" "Multinucleated layer with eosinophilic cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3157.jpg" -"3158" "Based on the cellular organization, what layer is the tissue likely to be a part of?" "Endocardium" "Epidermis" "Gastrointestinal tract mucosa" "Respiratory epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3158.jpg" -"3159" "What do the clear spaces observed in the image most likely represent?" "Edematous changes in the tissue" "Mucoid extracellular matrix" "Areas of necrosis" "Lipid deposits within the tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3159.jpg" -"3160" "Based on the appearance of keratinocytes and overall tissue architecture, which condition does the tissue sample most likely represent?" "Actinic keratosis" "Psoriasis" "Verrucous lesion" "Lichen planus" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3160.jpg" -"3161" "What does the presence of dark brown pigmentation in the stromal tissue most likely represent?" "Hemosiderin deposits" "Melanin accumulation" "Anthracotic pigmentation" "Lipofuscin deposits" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3161.jpg" -"3162" "What is the morphology of the erythrocytes observed in the blood smear image?" "The erythrocytes are hypochromic with no central pallor." "The erythrocytes show considerable variation in shape." "The erythrocytes are predominantly normocytic with central pallor." "The erythrocytes are macrocytic without central pallor." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3162.jpg" -"3163" "Assessing the red blood cells in the image, what can be inferred about the presence of poikilocytosis or anisocytosis?" "Erythrocytes show distinct hypochromasia suggesting poikilocytosis." "There is no obvious poikilocytosis or anisocytosis within the erythrocytes." "There is visible poikilocytosis due to the evident variation in the shape of erythrocytes." "There is notable anisocytosis with erythrocytes varying widely in size." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3163.jpg" -"3164" "What histological characteristic distinguishes the outermost layer in this image?" "High concentration of neuronal cell bodies" "Abundance of thick collagenous fibers" "Sparsely distributed squamous cells" "Presence of Purkinje cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3164.jpg" -"3165" "What distinctive morphological changes are observed in the adipocytes?" "Clear cytoplasmic vacuolization" "Hyperchromatic nuclei" "Eosinophilic saponification" "Multinucleated giant cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3165.jpg" -"3166" "Regarding the inflammatory response present in the tissue, which type of infiltrate is most apparent?" "Granulomatous" "Mixed cell" "Neutrophilic" "Lymphocytic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3166.jpg" -"3167" "Considering the collagen distribution seen in this tissue section, which of the following findings could you reasonably rule out based on the image?" "Fibrosis" "Normal collagen distribution" "Edema" "Scarring" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3167.jpg" -"3168" "What is not observable in the basement membrane of this skin tissue section?" "Dermal-epidermal separation" "Thickening" "Normal thickness" "Lichenoid tissue reaction" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3168.jpg" -"3169" "Identify the structures observed at the top of the image that are lined by columnar epithelium?" "Renal tubules" "Gastric glands" "Alveolar sacs" "Intestinal villi" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3169.jpg" -"3170" "Based on the tissue architecture visible in the image, which of the following is not observed?" "Diffuse infiltration of large, pale histiocytes" "Well-formed granulomas" "Tight aggregates of epithelioid histiocytes" "Distinct clusters or nodules formed by histiocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3170.jpg" -"3171" "Based on the orientation and density of the fibers seen in the image, how would you classify the connective tissue?" "Regularly arranged loose connective tissue" "Irregularly arranged loose connective tissue" "Regularly arranged dense connective tissue" "Irregularly arranged dense connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3171.jpg" -"3172" "Based on the observation of the tissue section, which layer that is typically present on the skin surface appears to be absent?" "Stratum corneum" "Stratum granulosum" "Stratum basale" "Stratum lucidum" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3172.jpg" -"3173" "In the provided tissue section, which type of inflammatory pattern is evidenced by the visual characteristics?" "Lichenoid tissue reaction" "Spongiotic dermatitis" "Psoriasiform dermatitis" "Panniculitis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3173.jpg" -"3174" "Based on the cellular morphology observed in the image, which of the following findings might be misleading when assessing the potential for malignancy?" "Large, hyperchromatic, spindle-shaped cells with 'ugly nuclei'" "Hypercellular fascicles with significant mitotic activity" "Eosinophilic matrix with interspersed collagen fibers" "Scattered smaller, rounder nuclei resembling mast cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3174.jpg" -"3175" "What can be inferred about the glands observed in the submucosa layer?" "They are sweat glands involved in thermoregulation" "They are mixed glands producing both serous and mucous secretions" "They are mucous glands producing a thick, viscous secretion" "They are serous glands producing a watery secretion" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3175.jpg" -"3176" "What additional cell type can be inferred to be present based on the more abundant, paler cytoplasm amidst the lymphocytes?" "Mast cells" "Plasma cells" "Macrophages" "Fibroblasts" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3176.jpg" -"3177" "In the image, which process can be determined by the presence of eosinophilic material surrounding the adipocytes?" "Hyaline degeneration" "Lipolysis" "Fat saponification" "Steatosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3177.jpg" -"3178" "What feature of the inclusion within the neutrophil's cytoplasm, indicated by the lower arrow, distinguishes it from the surrounding granules?" "The inclusion is multi-lobed while the granules are round" "The inclusion is darker and more basophilic than other granules" "The inclusion is pale and less prominent compared to the granules" "The inclusion is larger and more distinct than the neighboring granules" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3178.jpg" -"3179" "Based on the epithelial cells visible in the tissue section, which of the following features best describes the cytoplasm?" "Abundant basophilic cytoplasm" "Scanty basophilic cytoplasm" "Eosinophilic cytoplasm" "Clear cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3179.jpg" -"3180" "Assessing the degree of cellular atypia in this section of the well-differentiated neoplastic process, which characteristic is not visible in the cells?" "Pleomorphism" "Uniform nuclear size" "Mitotic figures" "Nuclear hyperchromasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3180.jpg" -"3181" "What tissue characteristic is suggested by the presence of eosinophilic, fibrillary stroma in the image?" "Adipose tissue infiltration" "Neuroblastic origin" "Dense connective tissue" "Muscle tissue differentiation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3181.jpg" -"3182" "What cellular morphology is most prominent in the glands within the fibrous stroma of this tissue section?" "Spindle-shaped cells with elongated nuclei" "Squamous cells with central nuclei" "Polyhedral cells with hyperchromatic nuclei" "Columnar cells with basal nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3182.jpg" -"3183" "How do the nuclei of the glandular epithelial cells appear?" "Small and pyknotic" "Irregular with prominent nucleoli" "Large, pleomorphic, and multi-nucleated" "Round and basally located" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3183.jpg" -"3184" "What is the most likely histological stain used in this image based on the reddish-brown coloration seen in the tissue?" "Periodic acid-Schiff (PAS) stain" "Masson's trichrome stain" "Immunohistochemical stain for actin" "Hematoxylin and eosin (H&E) stain" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3184.jpg" -"3185" "Based on the orientation and morphology of the nuclei seen in the tissue, what type of sectioning is likely represented in this image?" "Tangential section" "Longitudinal section" "Oblique section" "Cross-sectional" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3185.jpg" -"3186" "What can be inferred about the granular cell layer in this tissue sample?" "A normal granular cell layer is present" "There is parakeratosis in the granular cell layer" "The granular cell layer is absent" "There is hyperkeratosis of the granular cell layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3186.jpg" -"3187" "Considering the cellular morphology, what is the cytoplasmic appearance of the cells lining the glandular structures in the provided image?" "Basophilic with a dark blue color" "Acidophilic with a pinkish color" "Neutrophilic with a neutral color" "Amphophilic with an intermediate color" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3187.jpg" -"3188" "Which feature in the image is compatible with a bony trabeculum?" "Eosinophilic, amorphous extracellular matrix" "Chondrocytes with rounded morphology" "More fibrous or dense tissue" "Chondrocytes within lacunae" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3188.jpg" -"3189" "What characteristic feature of the extracellular matrix is most apparent in this histological section stained with Hematoxylin and Eosin?" "Dense collagenous stroma" "Extensive hyalinization" "Prominent calcification" "Abundant myxoid matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3189.jpg" -"3190" "Upon examination of the vascular structures within this image, how would you describe the blood vessels?" "Surrounded by palisading neoplastic cells" "Highly irregular with evidence of atypia" "Lined with flat endothelial cells and lacking atypia" "Showing extensive branching and complex anastomoses" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3190.jpg" -"3191" "What feature of this histological section suggests the possibility of keratinized tissue at the edges of the image?" "The elongated, wavy lines" "The darker pink color" "The large, irregularly-shaped structures" "The smaller, tubular structures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3191.jpg" -"3192" "Based on the structural morphology, which type of blood vessel is predominantly featured in the histological section?" "Large arteries" "Lymphatic vessels" "Veins" "Capillaries" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3192.jpg" -"3193" "Assessing the colloid content within the follicles, which of the following best describes its appearance?" "High mitotic activity within the colloid" "Scant and pale colloid with areas of increased density" "Evenly dense and highly eosinophilic throughout" "The colloid exhibits prominent calcification" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3193.jpg" -"3194" "Based on the morphology seen in the image, what is the most likely nature of the eosinophilic deposits?" "Hyaline change" "Amyloid deposits" "Necrotic debris" "Fibrin material" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3194.jpg" -"3195" "Based on the histological features observed in the image, what is characteristic of the cellular morphology within the lesion?" "Eosinophilic cytoplasm and prominent nuclei" "Multi-nucleated giant cells" "Keratin pearl formation" "Neuroendocrine granules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3195.jpg" -"3196" "What can be inferred about the epidermal layer based on the cell morphology seen in this image?" "Presence of acanthosis" "Presence of parakeratosis" "Presence of spongiosis" "Presence of dyskeratosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3196.jpg" -"3197" "Based on the histologic features observed in the image, what type of cellular differentiation does the tumor most likely represent?" "Melanocytic differentiation" "Squamous differentiation" "Glandular differentiation" "Neuroendocrine differentiation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3197.jpg" -"3198" "Based on the tissue morphology observed, what feature is NOT evident in this histological sample that would suggest a more aggressive neoplastic process?" "Significant nuclear atypia" "Lobular architecture of the cell arrangement" "Numerous mitotic figures" "Clear or vacuolated cytoplasm in some cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3198.jpg" -"3199" "Based on the characteristics of the epidermal layer observed, what is the most likely condition described by the tissue morphology?" "Parakeratosis with retained nuclei in the stratum corneum" "Hyperplasia with thickened stratum corneum" "Atrophy with flattened cellular layers" "Papillomatosis with acanthosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3199.jpg" -"3200" "In the dermis, the accumulation of a homogenous material is consistent with what pathological change?" "Solar elastosis" "Amyloid deposition" "Fibrinoid necrosis" "Melanin accumulation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3200.jpg" -"3201" "Based on the cellular morphology, what is the predominant shape of the cells observed in the microscope image?" "Cuboidal" "Polyhedral" "Spherical" "Spindle-shaped" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3201.jpg" -"3202" "What best describes the clear space observed in the middle of the image?" "Granuloma with central necrosis" "Pseudocyst without an epithelial lining" "Keratin-filled cyst" "Vascular lumen" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3202.jpg" -"3203" "What is indicated by the presence of large cells with a foamy or fluffy cytoplasm surrounding the clear space?" "Histiocytes filled with a mucin-like substance" "Fibroblasts undergoing mitosis" "Adipocytes" "Neutrophils in acute inflammation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3203.jpg" -"3204" "Based on the histological features of the lesion, what is the most likely pathological process indicated by the pale, central band in this tissue biopsy?" "Dense fibrosis with collagen deposition" "Necrosis leading to loss of tissue structure" "Lipid accumulation within immune cells creating a xanthomatous lesion" "Highly cellular tumor with dense cellular arrangement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3204.jpg" -"3205" "What can be said about the luminal borders of the glands in the displayed endometrial tissue sample?" "The luminal borders appear as very tightly packed tubular structures with no cystic dilation." "The luminal borders show extensive papillary projections and complex architecture." "The luminal borders are uniformly smooth and well-defined." "The luminal borders are irregular with no clear uniformity." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3205.jpg" -"3206" "Considering the epithelial cell lining, what is the predominant morphology of the cells lining the endometrial glands?" "The cells lining the glands are predominantly flat and squamous." "The glands are lined with cuboidal cells showing signs of active secretion." "The epithelial cells are columnar and pseudostratified in some areas, suggesting active proliferation." "The lining consists of ciliated cells with a brush border characteristic of respiratory epithelium." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3206.jpg" -"3207" "Based on the microscopic examination of the tissue, what is the characteristic of the bone present?" "Well-organized bone with clear osteonal structure" "Immature, woven bone without distinct osteoblastic rimming" "Mature, lamellar bone with Haversian systems" "Irregularly shaped, calcified cartilage" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3207.jpg" -"3208" "What is the abnormal finding in the viable epidermal layers observed in the microscopic image of the tissue?" "Presence of melanocytes" "Dense inflammatory infiltrate" "Pale-staining cells" "Hyperkeratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3208.jpg" -"3209" "What does the homogeneous population of cells with round to oval nuclei and eosinophilic cytoplasm in the parenchyma most likely represent?" "Myeloid precursors" "A well-organized parenchymal tissue" "Erythroid precursors" "Megakaryocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3209.jpg" -"3210" "Which cellular morphology is predominantly observed in this tissue sample?" "Large, multinucleated giant cells" "Spindle-shaped cells with elongated nuclei" "Cuboidal cells with small, round, and centralized nuclei" "Small, round lymphocytes with dense nuclear chromatin" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3210.jpg" -"3211" "Identify the tissue surrounding the bony structures that is consistent with a layer involved in bone regeneration and repair." "The area with smaller, pinkish and elongated cells" "The light pink-stained area with less cellularity" "The purple-stained cartilaginous mass" "The lighter staining vesicular areas corresponding to fat" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3211.jpg" -"3212" "What histological feature distinguishes the suspected malignant mass in this image?" "Uniformity and lobulation of cells" "The presence of highly pleomorphic cells" "The presence of numerous mitotic figures" "Increased vascularization and hemorrhage" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3212.jpg" -"3213" "Based on the organization of the tissue adjacent to the suspected malignant mass, what is the most likely normal tissue it represents?" "Nervous tissue" "Skeletal muscle tissue" "Bony cortex with embedded osteocytes" "Adipose tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3213.jpg" -"3214" "Based on the image of the tissue section, what pattern is observed at the dermoepidermal junction?" "Uniform cell distribution with small, evenly spaced nuclei" "Irregular nests with atypical cells and pleomorphism" "Well-organized basal cell layer with regular mitotic figures" "Absence of cellular atypia and regular dermal collagen arrangement" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3214.jpg" -"3215" "Considering the variations seen in cellular architecture and potential for neoplastic processes, what feature within the tissue might be a sign of adenofibroma?" "Areas with significant inflammatory infiltrate and edema." "Dense cellular areas with high nucleus-to-cytoplasm ratio." "Regions showing necrosis and apoptosis." "Regions where the stroma appears decellularized and hypoechoic." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3215.jpg" -"3216" "What can be inferred about the architectural organization of the lymphoid tissue in this image?" "Lymphoid tissue is diffusely proliferative" "Abundant extracellular matrix" "Presence of granulomas" "Presence of well-formed lymphoid follicles" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3216.jpg" -"3217" "Considering the pathology present in the image, which statement best describes the pattern observed?" "Homogeneous cell populations with no evidence of tissue disruption" "Regular acinar structures typical of normal salivary gland tissue" "Hypercellularity with atypical nuclear features indicating high-grade dysplasia" "Alternating areas of pale-staining necrosis and darker inflammatory cell infiltrates" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3217.jpg" -"3218" "Based on the brown staining pattern observed in the low-power view, what does the distribution of cells with CD20 expression indicate?" "An absence of B-cells" "A localized cluster of B-cells" "A sparse infiltration of B-cells" "A widespread presence of B-cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3218.jpg" -"3219" "Based on the histopathological image provided, how do the epidermal rete ridges appear?" "Absent or flattened" "Elongated and somewhat club-shaped" "Shortened and blunt" "Regular and conical" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3219.jpg" -"3220" "What type of glandular structure is predominantly seen in this histological section of the skin?" "Sebaceous glands" "Eccrine sweat glands" "Apocrine sweat glands" "Salivary glands" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3220.jpg" -"3221" "Based on the cellular characteristics visible in this image, what is the predominant cell type within the glandular structures?" "Sebocytes" "Keratinocytes" "Adipocytes" "Myoepithelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3221.jpg" -"3222" "The epithelium that lines the glandular structures in this image is best described as:" "Simple squamous epithelium" "Simple cuboidal epithelium" "Stratified squamous epithelium" "Simple columnar epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3222.jpg" -"3223" "How would you describe the nuclear to cytoplasmic ratio observed in the majority of the cells in this image?" "High nuclear to cytoplasmic ratio" "Nuclear to cytoplasmic ratio suggesting mature cells" "Low nuclear to cytoplasmic ratio" "Nuclear to cytoplasmic ratio consistent across cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3223.jpg" -"3224" "What does the central aggregation of cells in the tissue most likely represent?" "Dental papilla" "Dental lamina" "Enamel organ" "Dental follicle" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3224.jpg" -"3225" "What is the role of the cell structure indicated by a dense surrounding layer resembling a flattened sheath?" "To form the dental pulp" "To give rise to odontoblasts that form dentin" "To secrete enamel as it differentiates into ameloblasts" "To initiate tooth development by the formation of tooth buds" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3225.jpg" -"3226" "Based on the morphological features observed in the image, how would you classify the glands present in the gastric mucosa specimen?" "Highly irregular and angulated glands" "Rounded, cystically dilated glands" "Glands with significant atypia" "Glands with frequent mitotic figures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3226.jpg" -"3227" "What feature is evident in the dermis?" "Uniformly distributed fibroblasts" "Inflammatory cell infiltrate and melanocyte nests" "Extensive vascular proliferation" "Absence of cellular activity" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3227.jpg" -"3228" "Observing the glandular structures in the image, what can be inferred about their morphology?" "They exhibit dysplasia." "They show characteristics of hyperplasia." "They have normal morphology." "They are indicative of neoplastic changes." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3228.jpg" -"3229" "In the cellular clusters forming the lobular structures, what is the nature of the cytoplasm observed?" "Neutrophilic cytoplasm" "Basophilic cytoplasm" "Eosinophilic cytoplasm" "Amphiphilic cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3229.jpg" -"3230" "By observing the nuclear characteristics, what can be inferred about the potential for dysplasia in the glandular cells?" "Hyperchromatic and enlarged nuclei without significant dysplasia" "The hypochromatic nature of the nuclei implies high-grade dysplasia" "The increased nuclear-cytoplasmic ratio confirms high-grade dysplasia" "The evenly spaced nuclei suggest an absence of proliferation and dysplasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3230.jpg" -"3231" "Based on the morphology, which feature in the image most accurately corresponds to an atypical structure that might be indicative of an organism, like a parasite?" "An atypical structure within the bronchus with segmentation and internal patterning" "The dark purple clusters within the tissue matrix" "The thickened lung septa between the alveoli" "The clear spaces suggestive of alveoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3231.jpg" -"3232" "What feature differentiates the smooth muscle cells from the fibroblasts in this tissue sample?" "The presence of striations in smooth muscle cells" "The more densely packed arrangement of the smooth muscle cells" "The larger nuclei in the fibroblasts" "The irregularly shaped nuclei in the smooth muscle cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3232.jpg" -"3233" "The tissue organization seen in the image suggests which of the following growth characteristics?" "Multinodular growth with extensive calcification" "Disorganized growth with widespread areas of necrosis" "Uniform, encapsulated growth with no areas of necrosis" "Poorly delineated growth with significant pleomorphism" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3233.jpg" -"3234" "Based on the appearance of epithelial cell nuclei within the elongated structures, which of the following best characterizes their distribution and morphology?" "Uniformly spaced with small, hyperchromatic nuclei" "Enlarged, dark, and closely spaced nuclei indicating hyperchromasia" "Regularly arranged nuclei with prominent nucleoli and ample cytoplasm" "Scattered nuclei with a clear halo and minimal atypia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3234.jpg" -"3235" "Based on the staining characteristics, what type of stain is likely used in this histological section?" "Giemsa" "Masson's Trichrome" "Periodic acid-Schiff" "H&E" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3235.jpg" -"3236" "Based on the image, what is the likely nature of the tissue architecture?" "Well-differentiated with uniform glandular structures" "Highly disorganized with significant pleomorphism" "Predominant spindle cell morphology" "Scarce stromal support with widespread necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3236.jpg" -"3237" "Based on the cellular morphology, what is the predominant cell type lining the surface of the tissue in the image?" "Basal cells" "Foveolar cells" "Squamous epithelial cells" "Transitional epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3237.jpg" -"3238" "What is the predominant nuclear morphology of the cells in this histological image?" "Elongated, spindle-shaped nuclei" "Hyperchromatic and pleomorphic nuclei" "Small, hyperchromatic nuclei with high mitotic rate" "Round nuclei with prominent nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3238.jpg" -"3239" "What is the predominant epithelial cell type visible in this histopathological image?" "Columnar epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "Squamous epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3239.jpg" -"3240" "Based on the nuclear characteristics observed in this image, which of the following best describes the cytological atypia?" "High mitotic index with atypical mitotic figures" "Severe hyperchromasia" "Nuclear to cytoplasmic ratio preserved without evident hyperchromasia" "Nucleomegaly with multiple nucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3240.jpg" -"3241" "What feature indicates the presence of muscle fiber alteration or potential denervation in this tissue sample?" "Peripheral location of multiple nuclei in the muscle fibers" "Uniform size and shape of muscle fibers" "Presence of centrally located nuclei within muscle fibers" "Lack of any nuclei within the muscle fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3241.jpg" -"3242" "What feature in the image suggests that these cells are capable of coordinated contraction?" "The presence of striations" "Irregular shape of the cells" "Multiple nuclei per cell" "Closely packed cells with minimal interstitial space" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3242.jpg" -"3243" "Based on the striations visible in the cells, what structure is most prominently depicted in this image?" "Dense bodies" "Z lines" "Sarcomeres" "Myofibrils" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3243.jpg" -"3244" "What is the morphology of the epidermal layer as seen in the image?" "Spongiosis with intercellular edema" "Acanthosis with elongation of rete ridges" "Intact stratum corneum with a largely unremarkable spinous layer" "Atrophy of the epidermal layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3244.jpg" -"3245" "What is the structure highlighted by the clear halo with a darker center within the dermis?" "Blood vessel" "Collagen bundle" "Microfilarial organism" "Nerve fiber" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3245.jpg" -"3246" "Based on the infiltration pattern observed in the epidermis, which type of cellular presence can be inferred?" "Keratinocyte hyperplasia" "Neutrophilic infiltration" "Lymphocytic exocytosis" "Melanocytic proliferation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3246.jpg" -"3247" "What feature, that is commonly seen with inflammatory infiltrates in the epidermis, is notably absent in this image?" "Hypergranulosis" "Acantholysis" "Parakeratosis" "Spongiosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3247.jpg" -"3248" "What morphological features of the lymphocytes are evident in this image?" "Cytoplasmic vacuolization and mitotic figures" "Multinucleation and necrosis" "Atypical size and hyperchromatic nuclei" "Uniform small size and euchromatic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3248.jpg" -"3249" "Which type of epithelium lines the lumen in the provided image?" "Stratified squamous epithelium" "Transitional epithelium" "Simple squamous epithelium" "Simple cuboidal epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3249.jpg" -"3250" "Based on the structure and the layers observed, which part of the urinary tract is most likely represented by the provided image?" "Renal tubule" "Urethra" "Urinary bladder" "Ureter" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3250.jpg" -"3251" "What is the correct pairing of the muscular layers seen in the image?" "Inner circular layer and outer longitudinal layer" "Two layers of circular muscle" "Two layers of longitudinal muscle" "Inner longitudinal layer and outer circular layer" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3251.jpg" -"3252" "Based on the observed morphology, which description best matches the stromal characteristics of the tissue in this image?" "Predominantly myxoid stroma with a classic appearance" "Largely acellular, hyaline stroma with amorphous pink material" "Edematous stroma with evidence of significant lymphocytic infiltration" "Highly cellular, fibrillar stroma with a mix of eosinophilic and myxoid areas" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3252.jpg" -"3253" "What is the predominant type of tissue observed in the dermal layer of this skin section?" "Adipose tissue" "Hyaline cartilage" "Dense irregular connective tissue" "Loose connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3253.jpg" -"3254" "Based on the appearance of the stratum corneum, how would you classify the thickness of the epidermis in this skin section?" "Thin, with a prominent stratum corneum" "Thick, with multiple layers of the stratum corneum" "Thick, with a well-developed stratum corneum" "Thin, with a barely visible stratum corneum" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3254.jpg" -"3255" "What pattern best describes the MLH1 protein staining observed at the base of the crypts in this tissue section?" "No staining observed" "Homogeneous and weak staining" "Homogeneous and intense staining" "Heterogeneous and intense staining" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3255.jpg" -"3256" "What is the most likely anatomical location of the tissue depicted in this immunohistochemical stain?" "Colon" "Esophagus" "Stomach" "Small intestine" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3256.jpg" -"3257" "Considering the appearance of the crypts in terms of their spacing and morphology, what pathological condition could they be indicative of?" "Traditional serrated adenoma" "Sessile serrated lesion" "Tubular adenoma" "Hyperplastic non-neoplastic tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3257.jpg" -"3258" "Based on the appearance of the cell nuclei, what can be inferred about the activity of these cells?" "They are actively dividing." "They are undergoing apoptosis." "They are likely quiescent." "They show signs of necrosis." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3258.jpg" -"3259" "In the image, where are the perinuclear hof areas located?" "Surrounding the entire nucleus of the lymphocytes" "Adjacent to the nuclei of the larger cells" "At the periphery of the epithelial cells" "Inside the nuclei of the myocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3259.jpg" -"3260" "By closely examining the branching structures within the thrombus, how would you characterize their morphology?" "Thick-walled with rare branching" "Broad-based with irregular branching" "Thin, regular, septate with acute angle branching" "Non-septate with wide angle branching" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3260.jpg" -"3261" "What can be inferred about the tissue response adjacent to the occluded vessel?" "The adjacent tissue shows signs of neoplastic transformation" "The tissue has no signs of an inflammatory response" "The tissue demonstrates necrosis with a lack of cellular structures" "There is evidence of preserved cellular structures with inflammatory cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3261.jpg" -"3262" "What features of the nuclei can be observed in this microscopic image?" "Nuclei with smooth nuclear membranes and small nucleoli" "Enlarged nuclei with prominent nucleoli and dispersed chromatin" "Multinucleation with variation in nuclear size and hyperchromatic chromatin" "Uniform, small nuclei with evenly dispersed chromatin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3262.jpg" -"3263" "How would you characterize the fibrous tissue of the cyst wall?" "Mixed with a high number of inflammatory cells" "Composed primarily of adipose tissue" "Dense with a high number of fibroblasts" "Loose with a low number of fibroblasts" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3263.jpg" -"3264" "What is the most notable feature of the epidermis in the provided skin histological section?" "Preservation of normal epidermal architecture" "Acantholysis" "Spongiosis" "Hyperkeratosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3264.jpg" -"3265" "Within the dermis of this skin section, how does the cellularity change as observed from the superficial to the deeper parts?" "Decrease in cellularity" "Constant cellularity" "Sporadic cellularity" "Increase in cellularity" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3265.jpg" -"3266" "The elongated, branching structures within the tissue most likely represent which of the following?" "Collagen bundles" "Nerve fibers" "Smooth muscle tissue" "Blood vessels" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3266.jpg" -"3267" "What staining technique is primarily represented in this image of connective tissue?" "Giemsa stain" "Periodic Acid-Schiff (PAS)" "Hematoxylin and Eosin (H&E)" "Masson's Trichrome" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3267.jpg" -"3268" "Identify the type of tissue adjacency shown at the periphery of the glandular structures in the prostate tissue section." "Sclerotic fibrous tissue surrounding the glands" "Adipose tissue with evidence of extraprostatic extension" "Dense lymphocytic infiltration next to glandular structures" "Smooth muscle tissue interspersed with glandular structures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3268.jpg" -"3269" "Identify the abnormal cellular inclusion observed in this tissue section." "Amyloid deposits" "Hemosiderin granules" "Lipid droplets" "Melanin pigment" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3269.jpg" -"3270" "What can be inferred about the continuity of the epidermal layer?" "The epidermal layer presents with uninterrupted continuity" "The epidermis is thickened with hyperkeratosis" "The epidermal layer is discontinuous, indicating erosion" "The epidermis exhibits parakeratosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3270.jpg" -"3271" "Based on the image, how would you describe the inflammatory infiltrate within the blister?" "Moderate infiltrate with multi-nucleated giant cells" "A band-like infiltrate at the dermal-epidermal junction" "Dense and diffuse infiltrate occupying the entire blister area" "Scattered and sparse infiltrate throughout the blister" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3271.jpg" -"3272" "What is the primary cellular organization type displayed within the tissue section?" "Sheet-like arrangement with abundant extracellular matrix" "Disorganized clusters without a specific pattern" "Tubular formations with lumen" "Densely packed spindle-shaped cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3272.jpg" -"3273" "Regarding the appearance of the chromatin within the nuclei, which description matches the observed microscopic findings?" "Chromatin with a speckled appearance throughout the nucleus" "Chromatin displaying a clear peripheral margination along the nuclear membrane" "Chromatin with a uniform pattern and even distribution" "Irregular chromatin pattern suggesting possible malignancy" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3273.jpg" -"3274" "What is the predominant pattern of epithelial cells arrangement within the glandular structure observed in the tissue?" "Signet ring cell pattern" "Palisading nucleus pattern" "Glandular pattern" "Rosette formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3274.jpg" -"3275" "The jet-black pigmented material scattered in the dermis is most consistent with what kind of substance?" "Lipofuscin as a byproduct of lysosomal digestion" "Exogenous pigment consistent with a tattoo" "Hemosiderin associated with hemorrhage" "Melanin pigment within melanocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3275.jpg" -"3276" "Based on the morphology of the cells within the circular glandular-like structure, what type of cellular pattern do they exhibit?" "Cells with abundant clear cytoplasm and central round nuclei" "Cells with multilayered, overlap without polarity" "Cells with hyperchromatic nuclei and a peripherally located eosinophilic rim" "Cells with dense, keratinized cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3276.jpg" -"3277" "What cellular characteristics best describe the surrounding stromal tissue that does not have an arrow pointing to it?" "Sparse cells with clear cytoplasm and indistinct nuclei" "Loose connective tissue with large, irregularly shaped cells" "Dense cells with lightly-staining cytoplasm and inconspicuous nuclei" "Dense cells with pink cytoplasm and dark-staining nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3277.jpg" -"3278" "What histological structure is indicated by the red arrow in this ovarian tissue section?" "Graafian follicle" "Secondary follicle with an antral cavity" "Corpus luteum" "Primordial follicle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3278.jpg" -"3279" "Considering the stage of development, what is the difference between the follicles indicated by the red and green arrows?" "The red arrow indicates a follicle without an antral cavity, while the green arrow points to one with an antral cavity." "The green arrow points to a more mature follicle with a larger antral cavity." "The red arrow indicates a follicle with a larger antral cavity than the green arrow." "The follicle at the green arrow has fewer layers of granulosa cells than the one at the red arrow." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3279.jpg" -"3280" "The collagenous extracellular matrix in this image presents as what type of appearance?" "Homogeneously acellular and dense" "Loosely arranged with mixed cellularity" "Pronounced haphazard arrangement with variable cellularity" "Well-organized with parallel alignment of fibers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3280.jpg" -"3281" "What type of nuclear atypia can be observed in the scattered large cells within this spindle cell population?" "Small, uniform nuclei with dense chromatin" "Hyperchromatic nuclei with prominent nucleoli" "Enlarged nuclei with finely dispersed chromatin" "Multilobated nuclei with inconspicuous nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3281.jpg" -"3282" "Based on the observed organization and characteristics of the stratified squamous epithelium, which condition does NOT appear to be present in the image?" "Dysplasia" "Active inflammation" "Keratinization" "Neoplastic changes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3282.jpg" -"3283" "What histopathological feature is indicated by areas of liver tissue with increased pink staining?" "Cellular injury or fibrosis" "Normal sinusoidal structures" "Large regenerative nodules" "Glycogen accumulation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3283.jpg" -"3284" "Based on the cellular morphology, how would you describe the epithelial cells lining the cystic structure?" "Hyperplastic epithelium with basaloid cells transitioning to squamous cells" "Ciliated columnar epithelial cells with goblet cells" "Simple squamous epithelium with thin, flattened cells" "Transitional epithelium typically seen in the bladder" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3284.jpg" -"3285" "In which panel do the epithelial cells display the earliest signs of variation in nuclear size and shape with some disorganization of the glandular structure?" "NFD" "HGD" "IFD" "LGD" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3285.jpg" -"3286" "Considering the overall morphology, which pathological condition is most consistent with the findings in this lung tissue sample?" "Langerhans' cell histiocytosis" "Usual interstitial pneumonia (UIP)" "Pulmonary alveolar proteinosis" "Anthracosilicosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3286.jpg" -"3287" "In the provided histopathological image, which of the following describes the distribution pattern of the eosinophilic material in the papillary dermis?" "Perivascular accentuation" "Sporadic and multifocal distribution" "Diffuse homogenous accumulation" "Subepidermal band-like distribution" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3287.jpg" -"3288" "Based on the provided microscopy, what is the condition of the epidermis directly above the eosinophilic deposits?" "Spongiosis with intercellular edema" "Hyperkeratosis with parakeratosis" "Acanthosis with notable thickening" "Atrophy showing thinning of the layer" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3288.jpg" -"3289" "What feature, although not clearly visible in this histopathological slide, would support a diagnosis of amyloidosis if present?" "Neutrophilic infiltrate surrounding the deposit" "Pigment incontinence in the dermis" "Microabscesses within the epidermis" "Munro's microabscesses at the stratum corneum" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3289.jpg" -"3290" "How would you describe the nuclear variation among the cells in this microscopic image?" "Significant pleomorphism with irregular nuclear contours" "Nuclei are uniform in size and shape" "Nuclei are round with conspicuous nucleoli" "Nuclei show slight variation in size" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3290.jpg" -"3291" "In this image, what is the chromatin pattern seen within the larger atypical cells?" "Homogeneous and finely distributed" "Condensed and marginated at the nuclear periphery" "Vesicular with prominent nucleoli" "Unevenly distributed with large chromatin blocks" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3291.jpg" -"3292" "What characteristic of the nuclei can be observed in the cells of this histological image?" "Uniform size and shape (monomorphism)" "Significant variation in size (anisocytosis)" "Marked variation in shape (pleomorphism)" "Multi-nucleation within individual cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3292.jpg" -"3293" "In the given histological image, which feature describes the cellular density surrounding the blood vessel?" "Dysplastic tissue with atypical cellular organization" "Hypercellular region with overgrowth of cells" "Paucicellular region with fewer cells" "Necrotic tissue lacking viable cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3293.jpg" -"3294" "Based on the granulation and morphology of the nuclei, which cells are readily identified in this microscopic image of a hematopoietic or lymphoid organ?" "Lymphocytes" "Monocytes" "Basophils" "Eosinophils" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3294.jpg" -"3295" "Based on the image, which of the following best describes the architectural changes in this epithelial tissue?" "Dysplasia with severe architectural disorder" "Suprabasal clefting without dysplasia" "Full-thickness epithelial dysplasia" "In-situ carcinoma with loss of polarity" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3295.jpg" -"3296" "What is the most likely histopathological finding depicted in this endometrial tissue section?" "A normal proliferative phase endometrium" "Simple endometrial hyperplasia without atypia" "Complex endometrial hyperplasia with atypia" "Endometrial carcinoma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3296.jpg" -"3297" "What cellular feature predominate in the dense aggregation of cells at the lower portion of the image?" "Abundant eosinophilic cytoplasm" "High nucleus-to-cytoplasm ratio" "Multinucleated giant cells" "Cytologic atypia with granular cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3297.jpg" -"3298" "Based on the morphology seen in the microscopic image, what is the likely staining method used?" "Masson's Trichrome staining" "Periodic Acid-Schiff (PAS) staining" "Giemsa staining" "Hematoxylin and Eosin (H&E) staining" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3298.jpg" -"3299" "When examining the epidermis, what morphological features of the keratinocytes indicate progressive maturation?" "Cell size augmentation and paler-staining cytoplasm as cells ascend" "Size reduction and hyperchromatic cytoplasm as cells ascend" "Increase of cytoplasmic basophilia in the surface layers" "Loss of nuclei in the uppermost layers of the epidermis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3299.jpg" -"3300" "How would you describe the chromatin pattern seen in the nuclei of the atypical cells in this image?" "Homogeneous and dense" "Hyperchromatic and clumped" "Vesicular with finely dispersed granules" "Euchromatic with prominent nucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3300.jpg" -"3301" "Upon examining the tissue stroma in this image, what can be deduced regarding the surrounding matrix?" "It is heavily collagenized with extensive fibrosis" "It appears moderately eosinophilic with inconsistent texture" "It shows prominent mucinous degeneration" "It is predominantly hyalinized" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3301.jpg" -"3302" "Based on the cellular morphology observed, what is the predominant nuclear characteristic of the epithelial cells?" "Uniform nuclei" "Anisonucleosis" "Marked pleomorphism" "Multinucleation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3302.jpg" -"3303" "Within the dermis, what arrangement of melanocytes is visible and is commonly associated with Spitz nevi?" "Random scattered distribution throughout the dermis" "Nesting in a pagetoid spread" "Cohesive fascicles against a fibrotic stroma" "Single-file arrangement between collagen bundles" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3303.jpg" -"3304" "How would you describe the overall cellularity of the tissue observed in the image?" "Highly cellular with closely packed cells" "Low cellularity with significant adipose tissue" "Sparse cellularity with abundant extracellular matrix" "Moderate cellularity with evenly dispersed cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3304.jpg" -"3305" "Regarding the area indicated by the white arrow, what is the most likely reason for the lack of staining?" "Deposition of lipid-rich substances like cholesterol" "High concentration of rapidly dividing cells" "Presence of air bubbles caused by slide preparation" "Accumulation of glycosaminoglycans" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3305.jpg" -"3306" "What does the staining pattern in the peripheral regions of the tissue section suggest?" "The presence of neuronal tissue" "The appearance of connective tissue" "An abundance of elastic fibers" "The structure of skeletal muscle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3306.jpg" -"3307" "Based on the cellular organization observed, what is the predominant architectural pattern of the lesion on the right side of the image?" "Cribriform" "Villous" "Papillary" "Solid nests" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3307.jpg" -"3308" "Considering the staining characteristics, what does the presence of deeply eosinophilic cytoplasm suggest about the cells in this image?" "Rich in cytochrome enzymes" "Abundant rough endoplasmic reticulum" "High lipid content" "Predominance of mitochondria" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3308.jpg" -"3309" "Which feature in this histological image is indicative of the telogen phase of the hair cycle?" "The fibrous stroma surrounding the hair follicles" "The elongated nuclei of fibroblasts within the dermal stroma" "The accumulation of cells around the outer root sheath" "The presence of keratinous material in some follicles" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3309.jpg" -"3310" "What describes the chromatin pattern within the nuclei of the cells observed in the image?" "Peripheral margination of chromatin" "Presence of nucleoli without hyperchromasia" "Uniformly dispersed chromatin" "Hyperchromasia with dense chromatin" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3310.jpg" -"3311" "How does the nuclei-to-cytoplasm ratio appear in many cells within this view?" "The nuclei-to-cytoplasm ratio varies widely among the cells." "Many cells exhibit a low nucleus-to-cytoplasm ratio." "Nuclei are inconspicuous, with cytoplasm being the more prominent feature." "Most cells in the image possess a high nucleus-to-cytoplasm ratio." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3311.jpg" -"3312" "What type of cellular infiltration is predominant in the lamina propria of this gastrointestinal tissue sample?" "Macrophages" "Lymphocytes" "Eosinophils" "Neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3312.jpg" -"3313" "Which cellular feature in this image could suggest that these are neurons observed in the tissue?" "Large centrally located nuclei within the cell bodies." "Small, densely packed nuclei indicative of rapidly dividing cells." "The spindle-shape of the cells with thick elongated cytoplasm." "Clear boundaries between the cells indicated by a lighter staining area, hinting at the presence of axon hillocks." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3313.jpg" -"3314" "What does the organization and morphology of the cells in the tissue primarily suggest?" "These are epithelial cells forming a lining of an organ." "The cells are indicative of a nervous tissue section, likely of the central nervous system." "These are individual myocytes scattered within a connective tissue matrix." "These cells represent a section of cardiac muscle tissue." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3314.jpg" -"3315" "Which tissue component likely accounting for the fibrillar extracellular matrix visible at higher magnification?" "Loose connective tissue" "Reticular fibers" "Dense irregular connective tissue" "Hyaline cartilage" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3315.jpg" -"3316" "What type of connective tissue is most prominent in the image, providing structural support to the glandular and adipose tissues?" "Elastic connective tissue" "Loose connective tissue" "Dense connective tissue" "Reticular connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3316.jpg" -"3317" "What type of tissue morphology does the cellular arrangement in clusters with clear spaces between them suggest?" "Adipose tissue" "Dense connective tissue" "Neoplastic squamous tissue" "Healthy columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3317.jpg" -"3318" "What distinct cellular morphology can be observed in the larger cells of this tissue specimen?" "Eosinophilic cytoplasm." "Acidophilic cytoplasm." "Clear cytoplasm." "Basophilic cytoplasm." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3318.jpg" -"3319" "What can be said about the appearance of the nuclei regarding their staining properties?" "The nuclei are enlarged and hyperchromatic" "The nuclei exhibit a uniform staining pattern" "The nuclei appear small and pyknotic" "The nuclei are lightly stained (hypochromatic)" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3319.jpg" -"3320" "Evaluating the cytoplasm of the epithelial cells in this image, what is its most notable characteristic?" "The cytoplasm is dense and amphophilic" "The cytoplasm contains numerous vacuoles" "The cytoplasm appears abundant and eosinophilic" "The cytoplasm is scant and basophilic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3320.jpg" -"3321" "Based on the atypical appearance of the stroma seen in the image, which process could be suggested?" "Increased cellularity and irregular organization" "Fibrosis indicative of chronic inflammation" "Regular and low-density adipose tissue" "Uniform fibrous tissue with no significant abnormality" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3321.jpg" -"3322" "Inspecting the morphology of the nuclei in the connective tissue, which characteristic is prevalent?" "Hyperchromasia" "Pleomorphism" "Uniformity in shape and size" "Multiple nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3322.jpg" -"3323" "What primary cell type is predominantly seen in the densely clustered areas within this connective tissue?" "Adipocytes" "Polymorphonuclear leukocytes" "Fibroblasts" "Lymphocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3323.jpg" -"3324" "Based on the tissue architecture and cellular variability, what type of pathological condition is most likely reflected in this microscopic image?" "Normal tissue homeostasis" "Neoplastic transformation" "Acute inflammation" "Chronic inflammation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3324.jpg" -"3325" "Considering the visible cellular arrangement, which feature is consistent with the normal histological appearance of the ovarian cortex within regions surrounding developing follicles?" "Disorganized layering of cells with varying nuclear sizes" "Two distinct layers of cells with different staining characteristics" "Uniform cellular distribution with homogenous nuclear appearance" "Predominantly empty spaces with few scattered cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3325.jpg" -"3326" "Upon examination of the spindle cells’ nuclei in this image, what can be inferred about their appearance?" "There is significant pleomorphism and hyperchromasia" "The nuclei are hyperchromatic with prominent nucleoli" "Nuclei are relatively uniform in shape and size" "There is a high mitotic index with abnormal mitotic figures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3326.jpg" -"3327" "Upon examination of the cytoplasm of the glandular cells, what is most evident?" "Cytoplasmic granularity with pigment deposition" "Deeply eosinophilic cytoplasm with increased cellularity" "Abundant clear cytoplasm with lipid accumulation" "Vacuolated cytoplasm suggesting lysosomal storage disease" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3327.jpg" -"3328" "In the context of diagnosing the type of skin lesion shown in the image, which of the features is least consistent with a classic presentation of a fibrous papule?" "Multinucleated cells within the lesion" "A foamy appearance within the cells" "Dense cellular proliferation in the center" "The layer consistent with epidermis at the periphery" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3328.jpg" -"3329" "Based on the arrangement and appearance of the cells in the image, which potential histopathological condition is suggested?" "High-grade dysplasia in Barrett's esophagus" "Well-differentiated liposarcoma" "Normal stratified squamous epithelium" "Invasive ductal carcinoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3329.jpg" -"3330" "What characteristic of the nuclei suggests active transcription and ongoing protein synthesis?" "The presence of multiple nucleoli within a single nucleus" "The irregular shape of the nuclei" "The vesicular appearance of chromatin" "The enlarged size of the nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3330.jpg" -"3331" "What type of epithelium surrounds the cystic structure observed in the microscopic image?" "Pseudostratified ciliated columnar epithelium" "Simple columnar epithelium" "Transitional epithelium" "Stratified squamous epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3331.jpg" -"3332" "What is the nature of the infiltrate observed in the connective tissue surrounding the cyst?" "Eosinophilic" "Granulomatous" "Neutrophilic" "Lymphocytic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3332.jpg" -"3333" "Based on the cell morphology, what characteristic feature can be observed in the cells within this microscopic image?" "Clear, structured tissue architecture" "Monomorphic cells with uniform nuclei" "Single nucleoli within the nuclei" "Spindle-shaped and rounded irregular cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3333.jpg" -"3334" "What is the appearance of the extracellular matrix in the stroma, as evidenced by the microscopic image of the tissue?" "Amorphous and homogeneous" "Clear and gel-like" "Basophilic and reticular" "Pinkish and fibrous" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3334.jpg" -"3335" "In evaluating the glandular epithelium in the provided image, which of the following best describes its organization?" "Stratified and keratinized" "Highly polarized with prominent nuclei" "Disorganized with disrupted areas" "Neatly organized and intact" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3335.jpg" -"3336" "Based on the glandular structures observed, what might be the pattern of spread?" "Lymphatic spread" "Bloodborne spread" "Direct invasion into adjacent tissue" "No evidence of spread" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3336.jpg" -"3337" "What can be inferred about the neoplastic process based on the nuclear atypia?" "Reactive atypia without neoplasm" "Benign neoplasm" "Malignant, low-grade tumor" "Malignant, high-grade tumor" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3337.jpg" -"3338" "Based on the characteristics of the cluster of cells encircled in green, what is the most likely identity of these cells?" "Ito cells with a clear cytoplasmic space" "Hepatocytes displaying active protein synthesis" "Endothelial cells lining the blood vessel" "Kupffer cells showing phagocytic activity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3338.jpg" -"3339" "What does the empty spacing within the epidermal layer suggest?" "Necrosis and loss of cells" "Presence of bacterial colonies" "Edema within the interstitial space" "Accumulation of lipid droplets" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3339.jpg" -"3340" "What describes the morphology of the endothelial cells lining the blood vessels in this tissue section?" "Cuboidal with basophilic cytoplasm" "Spindle-shaped with clear cytoplasm" "Plump with hyperchromatic nuclei" "Plump with eosinophilic cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3340.jpg" -"3341" "Observing the location and morphology, what best describes the function of the circled structures in the skin tissue sample?" "They are responsible for producing keratin for skin protection." "They are primarily involved in thermoregulation." "Their primary function is providing a sense of touch." "They play a key role in the synthesis of vitamin D." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3341.jpg" -"3342" "Based on the image, which structure is most likely associated with the transport of sweat to the skin surface?" "The most superficial cellular layer adjacent to the epidermis." "The circled structures exhibiting an 'onion skin appearance'." "The loose connective tissue surrounding the circled structures." "The elongated structure with a distinct lining." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3342.jpg" -"3343" "What does the predominant cellular morphology observed in this tissue section suggest regarding the potential origin of the tissue?" "Glandular epithelial origin" "Squamous epithelial origin" "Neural tissue origin" "Muscle tissue origin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3343.jpg" -"3344" "Based on the arrangement of nuclei and the amount of cytoplasm visible, what can be inferred about the tissue's activity status?" "The tissue is likely showing signs of active protein synthesis" "The tissue is potentially undergoing rapid division" "The tissue is likely in a resting state" "The tissue has cells in apoptosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3344.jpg" -"3345" "Based on the cellular morphology observed in the image, what type of cellular appearance predominates?" "Spindle-shaped cells with little cytoplasm" "Large, polygonal cells with abundant granular cytoplasm" "Anaplastic cells with highly variable shapes and sizes" "Small, round cells with high nucleus-to-cytoplasm ratio" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3345.jpg" -"3346" "Based on the cellular morphology, what is the most likely function of the structures highlighted by the red arrows?" "Conduit function" "Structural support" "Sensation" "Contraction" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3346.jpg" -"3347" "What type of epithelium predominantly lines the tubular structures indicated by the red arrows?" "Simple columnar epithelium" "Pseudostratified columnar epithelium" "Stratified squamous epithelium" "Simple squamous epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3347.jpg" -"3348" "What does the pattern of inflammation observed in the superficial dermis suggest?" "An acute purulent inflammation" "A spongiotic tissue reaction" "A granulomatous tissue reaction" "A lichenoid tissue reaction" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3348.jpg" -"3349" "Based on the stratification and variation in keratinocyte size and shape, which layer appears prominent and may indicate cell stress or damage?" "Stratum spinosum" "Stratum corneum" "Stratum lucidum" "Stratum granulosum" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3349.jpg" -"3350" "In the dermal layer of this skin section, what cell type predominates the inflammatory infiltrate?" "Eosinophils" "Neutrophils" "Macrophages" "Lymphocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3350.jpg" -"3351" "Which of the following is NOT observed in this histological image?" "Microabscesses in the dermal layer" "Neutrophilic infiltrate" "Papillary dermal edema" "Vascular changes in the dermis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3351.jpg" -"3352" "What type of cell morphology predominantly characterizes the tissue in this histopathological image?" "Round cells with dense nuclei" "Spindle-shaped cells with elongated nuclei" "Cuboidal cells with central nuclei" "Squamous cells with flat nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3352.jpg" -"3353" "In the provided image of the tissue, how would you describe the arrangement of the spaces in the mucinous or myxoid stroma among the cell clusters?" "Irregular and diffusely scattered" "Linear and branching" "Round and well-circumscribed" "Spindle-shaped with tapering ends" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3353.jpg" -"3354" "The clear space on the left side of the image most likely represents:" "Necrotic debris" "Spilled out mucus" "Collagen deposition" "Keratin accumulation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3354.jpg" -"3355" "What is the staining pattern on the left that surrounds the clear space indicative of?" "Adipose tissue" "Hyaline cartilage" "Myoepithelial cells" "Dense connective tissue indicating a reactive response" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3355.jpg" -"3356" "Which of the following features suggests a tissue reaction to a foreign body within the sample?" "Cells organized in a disordered fashion" "Multinucleated giant cells with foamy cytoplasm" "Basal lamina underlying the epithelial layer appearing intact" "Basophilic structure surrounded by palisading epithelioid cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3356.jpg" -"3357" "What can be inferred about the cell nuclei from this image?" "The nuclei are largely absent in the cells" "The nuclei are uniformly staining with high EMA expression" "The nuclei are darkly stained blue, indicating their presence" "There is a high variability in the size of the nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3357.jpg" -"3358" "Looking at the arrangement and morphological features of the cells, which statement is most accurate?" "Cells show extensive spindling and mesenchymal differentiation" "There is an absence of any discernible pattern, indicative of high-grade malignancy" "Cells are arranged in irregular clusters and aggregates with variable staining intensities" "Cells are arranged in a tightly-packed, honeycomb pattern suggestive of benign glandular tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3358.jpg" -"3359" "What structural feature can be identified in the non-circled areas reflecting the function of the gland?" "Blood vessels supplying the tissue" "Muscular tissue providing contractility" "Glandular ducts lined by epithelial cells" "Interstitial connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3359.jpg" -"3360" "Based on the histological features observed in this image, which cell shape predominantly characterizes the basal layer of the epithelium?" "Columnar or cuboidal cells" "Polygonal cells" "Spindle-shaped cells" "Squamous cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3360.jpg" -"3361" "Which structural feature is NOT visible in this image suggestive of a benign schwannoma?" "Verocay bodies" "Significant pleomorphism" "Antoni A pattern" "Mitotic figures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3361.jpg" -"3362" "What do the nuclei of the epithelial cells lining the glands suggest about the functional phase of the tissue?" "Secretory phase" "Atrophic phase" "Proliferative phase" "Menstrual phase" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3362.jpg" -"3363" "What is the predominant architectural pattern observed in the glandular structures of this tissue section?" "Spiral" "Cystic" "Papillary" "Tubular" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3363.jpg" -"3364" "What staining characteristics would you NOT expect to find in an examination of this lymphoid tissue sample?" "Uniform staining of all cellular and acellular components" "Darkly-stained nuclei of lymphocytes" "Brightly stained rod-shaped bacteria with an acid-fast stain" "'Foamy' appearance of the cytoplasm with an H&E stain" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3364.jpg" -"3365" "Regarding the observed tissue organization, what can be inferred about the vascular proliferation within this image?" "High endothelial venules typical of lymphoid tissue" "Multilayering of cells within the vessel walls" "An absence of signs of significant vascular proliferation" "Presence of glomeruloid vessels" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3365.jpg" -"3366" "Based on the tissue morphology, what does the epidermal layer of this skin biopsy most closely display?" "Complete absence of the stratum corneum" "Presence of parakeratosis" "Presence of a thick stratum spinosum" "Evidence of orthokeratosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3366.jpg" -"3367" "Which of the following best describes the state of the keratinocytes in the provided histological image of epidermal tissue?" "Evenly stained keratinocytes with uniform cytoplasm" "Lack of visible intercellular spaces between keratinocytes" "Slightly paler-staining cytoplasm in the keratinocytes" "Hypergranulosis with increased granular layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3367.jpg" -"3368" "What pathological feature is evident in the stratum corneum of the epidermis in this image?" "Acantholysis with loss of cohesion between keratinocytes" "Necrosis with loss of nuclei and cell structure" "Hyperkeratosis with thickened stratum corneum" "Parakeratosis with retention of nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3368.jpg" -"3369" "In the context of the cellular infiltration observed in the epidermis and stratum corneum, which type of inflammatory cell is present within this section of skin tissue?" "Neutrophils" "Lymphocytes" "Macrophages" "Eosinophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3369.jpg" -"3370" "What can be inferred about the cellular population in the dermis, based on the staining observed in the image?" "Presence of an acellular collagenous matrix" "Dense lymphocytic infiltrate" "Scattered angiogenesis and microvessels" "Fat adipocytes distributed within connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3370.jpg" -"3371" "Which feature in this image is not typical of normal thyroid epithelium?" "Uniform nuclear size and shape" "Monomorphism within the cellular population" "Cuboidal shape of cells" "Presence of elongated or irregularly shaped cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3371.jpg" -"3372" "What is the organization of the tissue architecture within the neoplasm?" "Chaotic with no clear organization" "Nested arrangement with nuclear palisading" "Lobular formations segregated by thin fibrous stroma" "Stellate reticulum-like arrangement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3372.jpg" -"3373" "In the densely populated areas of the microscopic image, which type of cell can primarily be identified by their pale cytoplasm and vesicular nuclei with variably prominent nucleoli?" "Erythrocytes" "Neutrophils" "Keratinocytes" "Histiocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3373.jpg" -"3374" "Analyzing the cellular composition within the connective tissue displayed, what observation can be made?" "Moderate cellular density with a mix of inflammatory and non-inflammatory cells" "High cellular density with abundant inflammatory cells" "Minimal cellular content suggesting an acellular matrix" "Dense clusters of neoplastic cells disrupting the collagen" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3374.jpg" -"3375" "In the context of the suspected diagnosis based on this image, which of the following signs are absent?" "Presence of inflammatory cells indicating active inflammation" "Regular arrangement of collagen fibers" "Disruption of collagen by other tissue or cell types" "Variability in the thickness and orientation of collagen fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3375.jpg" -"3376" "Assessing the cellularity of the tissue, which observation is accurate based on the microscopic characteristics visible in this image?" "The cellularity is diminished with abundant extracellular space" "The cellularity is high with inflammatory cells densely occupying the field" "The cellularity is moderate with balanced proportions of cells and extracellular matrix" "The cellularity is low, mostly showing fibrous tissues" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3376.jpg" -"3377" "How would you describe the arrangement of cells within the tissue section?" "Uniformly distributed with a clear glandular pattern" "Infiltrative growth pattern with high cellular atypia" "Haphazard arrangement without a clear pattern" "Organoid nesting with palisading nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3377.jpg" -"3378" "What characteristic best describes the endothelial cells lining the vascular channels?" "The endothelial cells are thin and elongated" "The endothelial cells are plump and epithelioid in appearance" "The endothelial cells are hyperchromatic with increased mitotic activity" "The endothelial cells are spindled with abundant eosinophilic cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3378.jpg" -"3379" "Considering the vascular lesions observed, which pattern seems to be indicated by the dense cellular proliferation?" "A lobular growth pattern" "A diffuse infiltrative pattern" "An organoid nesting pattern" "A linear, tract-like arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3379.jpg" -"3380" "What type of cellular arrangement can be observed in the image?" "Trabecular architecture" "Rosette-like formation" "Palisading pattern" "Disorganized clustering" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3380.jpg" -"3381" "Based on the histological features observed, what can be inferred about the differentiation status of the tissue in the image?" "Moderately differentiated" "Anaplastic" "Poorly differentiated" "Well-differentiated" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3381.jpg" -"3382" "What characteristic feature of the nuclei can be observed in the second microscopic image of the tissue section?" "Multinucleation" "Macronucleoli" "Molding of nuclei" "Prominent nucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3382.jpg" -"3383" "In the renal tissue presented in the image, how does the interstitium appear?" "Relatively acellular with minimal pink substance" "Infiltrated by numerous inflammatory cells" "Dense with fibrosis" "Interstitial edema with an amorphous pink substance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3383.jpg" -"3384" "What structural feature is conspicuously missing from the microscopic view of the renal tissue in this image?" "Distal tubules" "Blood vessels" "Glomeruli" "Proximal tubules with a brush border" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3384.jpg" -"3385" "Based on the morphology of the renal tubular epithelial cells, what type of vacuolization do these cells appear to exhibit?" "Isometric vacuolization" "Glycogenic vacuolization" "Fatty vacuolization" "Hydropic vacuolization" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3385.jpg" -"3386" "Based on the morphological features observed in this image, which of the following diagnostic possibilities is MOST consistent with the pathology displayed?" "Basal cell carcinoma" "Syringocystadenoma papilliferum" "Squamous cell carcinoma" "Sebaceous adenoma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3386.jpg" -"3387" "Observing the smaller, densely packed cells in the background, what cellular shape do they predominantly exhibit?" "Spherical" "Cuboidal" "Columnar" "Spindle-shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3387.jpg" -"3388" "What is the most likely origin of the larger cells in the field of view based on their morphology?" "Connective tissue" "Hematopoietic tissue" "Reproductive tissue" "Epithelial tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3388.jpg" -"3389" "What is the nature of the lining epithelium observed in this cystic structure?" "Transitional epithelium" "Stratified squamous epithelium with no keratinization" "Ciliated columnar epithelial cells" "Single layer of eosinophilic, keratinized cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3389.jpg" -"3390" "Based on the microscopic examination of the epidermis, which histological feature is prominent?" "Thin and atrophic epidermis" "Elongation of the rete ridges" "A prominent increase in the spinous layer (stratum spinosum)" "A prominent increase in the granular layer (stratum granulosum)" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3390.jpg" -"3391" "What type of hyperkeratosis is displayed in the stratum corneum?" "Parakeratosis" "Compact hyperkeratosis" "Orthokeratosis" "Lamellar hyperkeratosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3391.jpg" -"3392" "What is the predominant shape of the nuclei of the cells in this tissue section?" "Irregular and spindled" "Uniform and polygonal" "Round to oval" "Highly pleomorphic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3392.jpg" -"3393" "What is the predominant staining characteristic of the mucin pools seen in the image?" "Hematoxylinophilic" "Basophilic" "Amphiphilic" "Eosinophilic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3393.jpg" -"3394" "The cells surrounding the mucin pools possess certain nuclear features. Which of the following is NOT one of them?" "High nuclear-to-cytoplasmic ratio" "Uniform nuclear size" "Prominent nucleoli" "Multinucleation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3394.jpg" -"3395" "What is the characteristic feature observed around some blood vessels in this tissue section?" "Inflammatory infiltrate" "Fibrovascular cores" "Necrosis" "Pseudorosette formation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3395.jpg" -"3396" "Which feature in the image is indicative of phagocytosis activity by macrophages or histiocytes?" "Pink cytoplasmic areas without visible structures" "Round cells with compact nuclei" "Rod-like structures with dark stained core" "Densely clustered cellular formations" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3396.jpg" -"3397" "What does the presence of densely clustered cellular formations with pink to purple cytoplasm in the image suggest?" "Active hematopoietic tissue" "Adipose tissue" "Necrotic tissue" "Ongoing reparative or fibrotic process" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3397.jpg" -"3398" "Based on the morphological characteristics of the cells as seen in the image, which type of cell abnormality can be observed?" "Cells with large, centrally positioned nucleoli" "Multinucleated giant cells with dispersed chromatin" "Uniform cells with a single central nucleus" "Signet-ring cells with eccentrically placed nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3398.jpg" -"3399" "What does the variation in staining intensity within the cells most likely indicate?" "Variation in cell life cycle stages" "Presence of different cell types within the same tissue" "Variation in iron content within the cells" "Differential expression of surface markers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3399.jpg" -"3400" "Considering the pale eosinophilic extracellular matrix and the inclusion-like structures within the cells, what is the most likely histochemical stain used for this sample?" "Prussian blue iron stain" "Periodic acid-Schiff stain" "Hematoxylin and Eosin stain" "Acid-fast bacilli stain" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3400.jpg" -"3401" "How do the crypts within the intestinal tissue appear in the image?" "The crypts show hyperplastic changes" "The crypts exhibit neoplastic transformation" "The crypts appear normal with well-preserved architecture" "The crypts are distorted or disrupted" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3401.jpg" -"3402" "What morphological feature is characteristic of the cells within the nodules in this tissue section?" "Hyperchromatic nuclei with irregular shapes" "Sparse cytoplasm with few organelles" "Clear cytoplasm with perinuclear halos" "Eosinophilic cytoplasm indicative of abundant cytoplasmic content" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3402.jpg" -"3403" "Considering the morphology and arrangement of the tissues, which diagnosis is most consistent with this microscopic image?" "Metastatic melanoma with angiotropism" "Adenocarcinoma with desmoplastic reaction" "Oncocytoma with trabecular pattern" "High-grade sarcoma with hemorrhagic necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3403.jpg" -"3404" "Which layer of skin shows separation from the underlying tissue in this image?" "Stratum corneum" "Subcutaneous tissue" "Dermis" "Stratum basale" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3404.jpg" -"3405" "The white spaces resembling channels or vessels within the connective tissue, as visualized in the image, suggest the possibility of which of the following?" "Pathological dilatation of lymphatic vessels" "Artifactual gaps due to tissue processing" "Intracellular spaces within epithelial cells" "Normal vascular structures within the tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3405.jpg" -"3406" "What does the presence of cells with abundant eosinophilic cytoplasm chiefly represent in this histological image?" "Histiocytes in an inflammatory process" "Benign epithelial cells" "Normal glandular cells" "Red blood cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3406.jpg" -"3407" "Based on the tissue morphology observed in this microscopic image, what is the predominant type of epithelium lining the tubular structures?" "Pseudostratified columnar epithelium" "Simple cuboidal epithelium" "Stratified squamous epithelium" "Simple columnar epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3407.jpg" -"3408" "What is the nature of the stromal response observed in the connective tissue layer beneath the epithelium?" "Consistent with a strong fibroblastic and collagenous proliferation" "Composed mostly of hyaline cartilage with a uniform appearance" "Primarily characterized by mature adipose tissue with minimal inflammation" "Dominated by inflammatory cell infiltrate with occasional blood vessels" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3408.jpg" -"3409" "Which cell in this image represents the most mature stage of neutrophilic development?" "The cell with the large, irregularly shaped nucleus and condensed chromatin" "The cell with a band-shaped nucleus and less condensed chromatin" "The cell with the most condensed chromatin and smallest nucleus" "The cell with the clover-leaf shaped nucleus" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3409.jpg" -"3410" "What is the predominant morphological characteristic of the blood vessels observed in the papillary dermis?" "The blood vessels display extensive branching and anastomosis." "The blood vessels exhibit thick, muscular walls with prominent hyperplasia." "The blood vessels are elongated and dilated with thin walls." "The blood vessels show evidence of endothelial disruption and disorganization." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3410.jpg" -"3411" "What is the apparent condition of the epidermis as observed in the image?" "The epidermis appears compact and displays slight acanthosis." "The epidermis is atrophic with a loss of normal architecture." "The epidermis shows edema and significant intraepidermal vesicle formation." "There is an apparent acantholysis with loss of cohesion between keratinocytes." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3411.jpg" -"3412" "How would you describe the cellular density of the surrounding stroma?" "The stroma appears hypocellular with scant spindle-shaped cells." "There is a high cellular density with numerous atypical, pleomorphic cells." "The stroma displays a moderate cellular density with spindle-shaped cells." "The cellular density is low, but the cells present display marked atypia." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3412.jpg" -"3413" "What is the predominant nuclear characteristic observed in the upper layers of the epithelial cells in this tissue sample?" "Small nuclei with prominent nucleoli" "Dense chromatin with absent nucleoli" "Enlarged nuclei with irregular contours" "Uniformly small and hyperchromatic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3413.jpg" -"3414" "What cytoplasmic feature is most apparent in the affected epithelial cells?" "Eosinophilic granular cytoplasm" "Pale gray appearance, occasionally vacuolated" "Cytoplasm with multiple well-defined granules" "Abundant, dark-staining cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3414.jpg" -"3415" "Considering the presence of a loose connective tissue matrix with moderate inflammatory infiltrate, what best describes the likely histopathological context of this image?" "Granulomatous inflammation" "Acute inflammation" "Chronic inflammation" "Healing tissue with granulation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3415.jpg" -"3416" "Based on the image of the histological section, what is the predominant feature of the cells surrounding the fibrovascular cores?" "Extensive cytoplasmic vacuolation" "Dense hyperchromatic nuclei" "Clear cytoplasm" "Abundant eosinophilic cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3416.jpg" -"3417" "What is the appearance of nuclear cytoplasmic boundaries within the cells in this tissue sample?" "Sharp, distinct boundaries with uniform nuclei" "Indistinct boundaries with high nucleus-to-cytoplasm ratio" "Ill-defined borders with smudged chromatin" "Fuzzy boundaries with pleomorphic nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3417.jpg" -"3418" "Based on the density and staining characteristics of the cells in the dermis, what type of nodules are most likely present?" "Basaloid nodules" "Vascular nodules" "Lipomatous nodules" "Lymphoid nodules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3418.jpg" -"3419" "What is the appearance of the stroma within the nodules compared to the surrounding dermal connective tissue?" "Contains predominant fibroblasts" "Appears as tumor-associated stroma rather than normal fibrous connective tissue" "Hypercellular with pleomorphic cells" "Less cellular with a myxoid appearance" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3419.jpg" -"3420" "Upon examination of the surrounding connective tissue in the image, what observation supports the lack of a malignant process?" "The presence of extensive desmoplasia" "Lack of significant inflammatory infiltrate" "The disorganized stromal architecture" "The absence of reactive changes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3420.jpg" -"3421" "Considering the histological features observed in the image, which type of lesion does the morphology suggest?" "A benign lesion with downward proliferation such as a wart" "An in situ carcinoma with keratin pearl formation" "A malignant melanoma with atypical melanocytes" "A squamous cell carcinoma with evidence of invasion" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3421.jpg" -"3422" "What is the most likely identity of the cell indicated by the yellow arrow based on the cytoplasmic staining characteristics?" "Melanocyte" "Lymphocyte" "Keratinocyte" "Neutrophil" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3422.jpg" -"3423" "Based on the observable characteristics of the cells within the epithelial structures, what is the predominant nuclear feature?" "Monomorphic nuclei with uniform size" "Hyperchromatic nuclei with irregular contours" "Vesicular nuclei with large nucleoli" "Hypochromatic nuclei with prominent nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3423.jpg" -"3424" "What architecture do the epithelial structures with a fibrovascular core exhibit?" "Micropapillary clusters with scant stroma" "Glandular structures with luminal spaces" "Trabecular pattern with rosette formation" "Solid nests with central necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3424.jpg" -"3425" "Focusing on the relationship between the cellular and stromal components, which observation would you expect to find based on the given image?" "Anaplastic cells with effacement of stromal architecture" "Interconnected trabeculae blending with the surrounding stroma" "Fibrous encapsulation separating the cellular structures" "A clear distinction between the epithelial clusters and the surrounding stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3425.jpg" -"3426" "In the given microscopic image, which type of cells can be identified by their large rounded to ovoid nuclei and notable nucleoli?" "Fibroblasts" "Erythrocytes" "Eosinophils" "Endothelial cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3426.jpg" -"3427" "Based on the cellular composition around the vessel structure, which type of cells predominantly infiltrate the tissue?" "Macrophages" "Eosinophils" "Neutrophils" "Lymphocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3427.jpg" -"3428" "Which of the following best describes the appearance of the epidermis in the provided image?" "The epidermis exhibits psoriasiform hyperplasia." "The epidermis demonstrates a normal stratified squamous epithelial morphology." "The epidermis shows atrophy with loss of rete ridges." "The epidermis is characterized by thick keratinization and parakeratosis." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3428.jpg" -"3429" "Based on the characteristics of the nuclei observed in this histological image, which of the following descriptions is most accurate?" "The nuclei have round to oval shapes and are dark blue to purple." "The nuclei are large with prominent nucleoli." "The nuclei display multiple nucleoli and irregular chromatin distribution." "The nuclei exhibit significant pleomorphism." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3429.jpg" -"3430" "In the given microscopic image, the nuclei of the cells are best described as:" "Large with prominent nucleoli" "Multinucleated with a single central nucleolus" "Hyperchromatic and small" "Vesicular with peripheral margination of chromatin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3430.jpg" -"3431" "Assessing the arrangement of cells in this tissue section, which description aligns most closely with the cellular pattern:" "Cells are uniformly distributed and well-differentiated" "Cells are organized into well-formed glands" "Cells are arranged in an unstructured, irregular manner" "Cells exhibit a storiform pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3431.jpg" -"3432" "Based on the cellular morphology observed in the microscopic image, what is the predominant shape of the cells present within this section of tissue?" "Round" "Spindle-shaped" "Polygonal" "Oval" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3432.jpg" -"3433" "What pattern is predominantly seen in the glandular architecture of this tissue section?" "Papillary" "Trabecular" "Cribriform" "Solid" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3433.jpg" -"3434" "What does the dense pink-staining area at the top-left corner of the image likely represent?" "Muscle tissue" "Connective tissue" "Adipose tissue" "Neural tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3434.jpg" -"3435" "In the regions away from the dense pink-staining area, what is the likely histological feature being observed?" "Alveolar spaces from lung tissue" "Villi from intestinal tissue" "Normal hepatocytes from liver tissue" "Tubules from kidney tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3435.jpg" -"3436" "Which finding is indicative of a benign neoplasm in this histological image of skin tissue?" "Proliferation of melanocytes at the dermoepidermal junction" "Lack of a defined neoplastic border" "Deep invasive growth patterns" "Areas of necrosis within the epidermis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3436.jpg" -"3437" "What does the glandular epithelial organization suggest in terms of cellular arrangement?" "Papillary structures with irregularity" "Uniform tubular structures" "Smooth, flat epithelial lining" "Regular acinar formations" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3437.jpg" -"3438" "When examining the nuclear features of the epithelial cells, what are the predominant characteristics observed?" "Small, uniform nuclei with inconspicuous nucleoli" "Variation in nuclear size and shape with macronucleoli" "Large, uniform nuclei with small nucleoli" "Binucleation with small, regular nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3438.jpg" -"3439" "What is indicated by the presence of cells with dark-brown pigmentation scattered throughout the liver tissue?" "Lipofuscin accumulation" "Anthracotic pigmentation" "Melanin deposition" "Hemosiderin-laden macrophages" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3439.jpg" -"3440" "Based on the bridging of central veins by necrotic cells observed, what might be the morphologic pattern that this liver tissue is likely developing into?" "Steatohepatitic pattern" "Cholestatic liver disease pattern" "Nutmeg liver appearance" "Cirrhosis with regenerative nodules" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3440.jpg" -"3441" "Looking at the cellular organization in the epithelial sheets, how would you characterize their arrangement?" "Palisading nuclei commonly observed in gliomas" "Uniform, well-differentiated cellular arrangement" "Randomized, with a significant loss of polarity" "Rosette-like structures typically seen in neuroendocrine tumors" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3441.jpg" -"3442" "Considering the appearance of the cytoplasm in the abnormal cells, what specific change can be observed?" "Vacuolated 'clear cell' alterations" "Abundant eosinophilic cytoplasm typical of oncocytic changes" "Cytoplasm with heavy melanin pigmentation" "Hypergranular cytoplasm indicative of granular cell tumors" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3442.jpg" -"3443" "What feature is absent in the organization of this tissue that would make it atypical for scar tissue?" "Heterogeneous staining" "Lack of vascular structures" "Anisotropic arrangement of cells" "Dense cellular packing" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3443.jpg" -"3444" "What does the eosinophilic staining pattern suggest in the context of this image?" "Necrotic tissue" "Calcified matrix" "High lipid content" "Fibrotic tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3444.jpg" -"3445" "Observing the surrounding stroma in the image, what is the absence of a desmoplastic reaction indicative of?" "Medullary carcinoma" "Benign intraductal papilloma" "Lobular carcinoma in situ" "Invasive ductal carcinoma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3445.jpg" -"3446" "What is the architecture of the cellular islands observed in the histopathological image?" "Tubular" "Solid" "Cribriform" "Papillary" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3446.jpg" -"3447" "How would you describe the appearance of the nuclei within the basaloid cells in the image?" "Vesicular with prominent nucleoli" "Hyperchromatic and palisading at the periphery" "Enlarged with smudged chromatin" "Clear with marginal condensation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3447.jpg" -"3448" "Based on the microscopic features observed in the lung tissue, which process is likely occurring within the alveolar walls?" "Accumulation of neoplastic cells within the alveolar walls" "Normal alveolar wall thickness without any significant change" "Thinning of the alveolar walls indicating emphysematous change" "Thickening of the alveolar walls with fibrotic tissue deposition" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3448.jpg" -"3449" "What is the predominant cell type visible in the tissue section based on their morphology?" "Cuboidal epithelial cells" "Spindle cells" "Adipocytes" "Squamous epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3449.jpg" -"3450" "What additional histological feature can be identified in the tissue section that suggests a specific stromal change?" "Necrosis" "Calcification" "Myxoid background" "Hyalinization" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3450.jpg" -"3451" "Given the structure and layers observed, where in the body might this type of epithelium be commonly found?" "Lining of the urinary bladder" "Inner surface of the cheek (buccal mucosa)" "Wall of alveoli in the lungs" "Inner lining of blood vessels (endothelium)" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3451.jpg" -"3452" "What evidence in the image indicates an ongoing inflammatory response?" "Presence of lymphocytes and plasma cells" "Presence of fibroblasts and myofibroblasts" "Presence of eosinophils and hemorrhage" "Presence of macrophages and neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3452.jpg" -"3453" "What features are observed in the top left histological section?" "Spindle-shaped cells with a pink-staining fibrous matrix" "Osteoid matrices with hyperchromatic cells" "Neoplastic osteoid with osteoblastic rimming" "Small blue cells with high nuclear-to-cytoplasmic ratio" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3453.jpg" -"3454" "Identify the features present in the bottom right section of the image." "Small blue cells with little cytoplasm and multinucleated giant cells" "Eosinophilic amorphous osteoid matrices surrounded by atypical cells" "Spindle-shaped cells with oval nuclei" "Neoplastic osteoid with variable cytoplasm and concentric rimming pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3454.jpg" -"3455" "In the top right section, what indicates an actively proliferating tumor?" "Presence of ample cytoplasm and osteoblastic lineage" "High nuclear-to-cytoplasmic ratio" "Eosinophilic osteoid matrices with hyperchromatic, pleomorphic cells" "Spindle cell pattern within a fibrous matrix" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3455.jpg" -"3456" "Based on the tissue morphology, what pattern can be observed in the arrangement of the cells?" "Syncytial growth pattern" "Whorled pattern" "Nested or floret-like pattern" "Indian file pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3456.jpg" -"3457" "Examining the cytoplasm of the cells, how would you characterize it in terms of its appearance in this microscopic view?" "Pale cytoplasm with eccentric placement of the nucleus" "Pale and vacuolated cytoplasm" "Abundant eosinophilic cytoplasm" "Basophilic cytoplasm with perinuclear clearing" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3457.jpg" -"3458" "What is the level of cellular atypia present in the observed ductal spaces?" "High-grade with extensive pleomorphism and necrosis" "Moderate atypia with some nuclear enlargement" "Mild atypia with minimal pleomorphism" "No overt sign of high-grade cytologic atypia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3458.jpg" -"3459" "How do the nuclei in the spinous layer appear?" "Large and prominent" "Small and pyknotic" "Normal in size and inconspicuous" "Absent or pyknotic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3459.jpg" -"3460" "Based on the microscopic examination, what is the nature of the bone matrix observed?" "The bone matrix shows a clear mosaic pattern indicative of Paget's disease" "The bone matrix indicates hypermineralized structures characteristic of osteopetrosis" "The bone matrix demonstrates well-organized, mature lamellar organization" "The bone matrix presents an irregular, woven bone pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3460.jpg" -"3461" "What does the histopathological image suggest about the melanocytes' growth pattern?" "There is a branched nest formation of melanocytes throughout the epithelium" "The melanocytes are exhibiting invasive growth into the underlying stroma" "No evidence of nests or invasive growth of melanocytes into the underlying stroma" "The melanocytes are displaying a pagetoid spread" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3461.jpg" -"3462" "What is the predominant growth pattern observed in the neoplasm?" "Alveolar" "Trabecular" "Papillary" "Follicular" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3462.jpg" -"3463" "What does the dense, granular appearance of the tissue predominantly indicate in this image?" "Deposition of extracellular matrix" "Accumulation of immune cells" "Abundance of renal tubules" "Presence of glomeruli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3463.jpg" -"3464" "Based on the microscopic features observed in the image, such as the presence of histiocytes, lymphocytes, and the eosinophilic area of necrosis, this tissue most likely represents a section from which anatomical location?" "Cutaneous tissue" "Hepatic tissue" "Renal tissue" "Pulmonary tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3464.jpg" -"3465" "What feature best describes the endothelial layer observed in the arterial wall in this histological section?" "A significantly thickened layer with increased cellularity" "A layer with decreased cellularity and thickened extracellular matrix" "A thin layer of cells consistent with normal endothelial lining" "Absence of endothelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3465.jpg" -"3466" "What type of tissue predominates in this microscopic field?" "Bone tissue" "Dense fibrous connective tissue" "Cardiac muscle tissue" "Adipose tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3466.jpg" -"3467" "What type of cellular infiltrate is visible in the interstitial spaces within this tissue sample?" "Neutrophils" "Eosinophils" "Lymphocytes" "Macrophages" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3467.jpg" -"3468" "What morphological feature best characterizes the inflammatory response seen in the small blood vessels of this tissue?" "Neutrophilic infiltration" "Lymphocytic infiltration" "Granulomatous inflammation" "Eosinophilic infiltration" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3468.jpg" -"3469" "What can be inferred about the nuclei of the cells in this tissue section?" "The nuclei are uniformly rounded with evenly distributed chromatin" "The nuclei are small and uniform in size" "The nuclei are large and hyperchromatic with irregular contours" "The nuclei are predominantly fragmented indicating apoptosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3469.jpg" -"3470" "Based on the cellular morphology observed, what is the most likely diagnosis represented in this image?" "Pleomorphic liposarcoma" "Well-differentiated liposarcoma" "Myxoid liposarcoma" "Dedifferentiated liposarcoma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3470.jpg" -"3471" "Based on the connective tissue characteristics observed in this image, what can be inferred about the extracellular matrix?" "The extracellular matrix exhibits large amounts of mucopolysaccharides" "The extracellular matrix contains decreased amounts of collagen" "The extracellular matrix is predominantly acellular with little to no collagen" "There are varying levels of collagen deposition in the extracellular matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3471.jpg" -"3472" "The subnuclear vacuoles seen in this image are typical for which phase of the menstrual cycle?" "Early secretory phase" "Menstrual phase" "Proliferative phase" "Late secretory phase" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3472.jpg" -"3473" "Based on the cell morphology and glandular architecture within the endometrial tissue shown in this image, which hormone's influence is suggested to be dominant?" "Testosterone" "Follicle-stimulating hormone (FSH)" "Estrogen" "Progesterone" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3473.jpg" -"3474" "What best describes the cytoplasm of the predominantly observed cells in the tissue section?" "Amphophilic with diffuse granularity" "Basophilic with few granules" "Clear with no evidence of granulation" "Eosinophilic with ample cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3474.jpg" -"3475" "Judging by the image, how would you classify the appearance of the nuclei within the cells in the dense cellular areas?" "Irregular, pleomorphic nuclei with variable staining" "Uniform, small, round nuclei with scant cytoplasm" "Large, round to oval nuclei with visible nucleoli" "Small, hyperchromatic nuclei with high nucleus-to-cytoplasm ratio" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3475.jpg" -"3476" "Based on the patterns of nuclear morphology, what pathological process could be suggested by the areas where cellular and nuclear details are less discrete?" "Hyperchromasia characteristic of increased DNA content" "Nuclear atypia associated with dysplasia" "Karyorrhexis indicative of nuclear fragmentation" "Multinucleation typical for giant cell formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3476.jpg" -"3477" "Based on the microscopic features visible in this image, which of the following elements of connective tissue stroma can be identified?" "Heavy lymphocytic infiltrate surrounding tissue clusters" "High degree of fibrosis with thick collagen bundles" "Abundant adipose tissue interspersed between cell clusters" "Vascular network and areas of pink, eosinophilic extracellular matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3477.jpg" -"3478" "What is the predominant cellular morphology observed in this tissue section stained with H&E?" "Giant cells with multiple nuclei and abundant cytoplasm" "Polygonal cells with abundant eosinophilic cytoplasm" "Spindle-shaped cells with elongated nuclei" "Basaloid cells with dark, basophilic nuclei and a variable amount of cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3478.jpg" -"3479" "Which of the following best describes the pattern of the tissue's architecture?" "Multiple areas of necrosis interrupting the tissue integrity" "Dense proliferation forming a solid mass with interspersed cystic spaces" "Disorganized growth with significant cellular pleomorphism" "Uniform glandular structures lined by columnar epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3479.jpg" -"3480" "Based on the cellular morphology, what is the characteristic feature of the cells' cytoplasm in this tissue sample?" "Darkly staining granules" "Abundant clear cytoplasm" "Numerous vacuoles" "Dense fibrous inclusions" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3480.jpg" -"3481" "Based on the presented canalicular staining pattern, what could be a potential diagnosis?" "Hepatocellular carcinoma" "Metastatic adenocarcinoma" "Cholangiocarcinoma" "Hepatic hemangioma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3481.jpg" -"3482" "What is the predominant pattern of the collagen distribution in the image?" "Eosinophilic bundles interspersed among cells" "Densely packed with minimal intervening stroma" "Randomly dispersed without a specific pattern" "Arranged in irregular clusters" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3482.jpg" -"3483" "Considering the organization of the cells and stroma, the tissue pictured is most likely from a:" "Loose areolar connective tissue with scattered cells" "Dense smooth muscle layer with abundant cytoplasmic filaments" "Fibroblastic or myofibroblastic proliferation" "Hyaline cartilage with chondrocytes in lacunae" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3483.jpg" -"3484" "What does the overall tissue organization observed in this image suggest about the physiological processes that may be associated with this tissue?" "Inflammatory response" "Oncogenic transformation" "Specialized functional change" "Regenerative healing" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3484.jpg" -"3485" "What level of the epidermis is primarily affected by the acantholysis as seen in the image?" "Stratum corneum" "Stratum spinosum" "Basal layer" "Superficial layers above the basal layer" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3485.jpg" -"3486" "What type of bone tissue is depicted at the center and bottom left, characterized by its microscopic features?" "Woven bone" "Spongy bone" "Mature lamellar bone" "Immature bone" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3486.jpg" -"3487" "What is the predominant staining characteristic of the fibrotic tissue observed in the image?" "Basophilic (blue-staining)" "Eosinophilic (pink-staining)" "Neutrophilic (neutral-staining)" "Chromophobic (pale-staining)" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3487.jpg" -"3488" "Which type of epithelial cells predominantly forms the organized layers in the displayed histological image?" "Squamous epithelial cells" "Columnar epithelial cells" "Transitional epithelial cells" "Cuboidal epithelial cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3488.jpg" -"3489" "Based on the cellular morphology, what is the central larger cell with the prominent nucleolus most likely to represent in the context of this tissue sample?" "A malignant cell" "A neoplastic plasma cell" "A normal endothelial cell" "An activated lymphocyte" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3489.jpg" -"3490" "How would you describe the collagen content surrounding the spindle cells?" "Dense eosinophilic collagen bundles" "Absence of collagen" "Sparse and disorganized collagen" "Myxoid collagen appearance" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3490.jpg" -"3491" "What type of extracellular deposits are visible within the cellular matrix in this image?" "Amyloid" "Hemosiderin" "Lipofuscin" "Calcospherites" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3491.jpg" -"3492" "Based on the structure and organization of cells in this micrograph, what histological layer is noticeably absent?" "Stratum lucidum" "Stratum granulosum" "Stratum corneum" "Basal layer" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3492.jpg" -"3493" "What is the predominant cell shape observed in this histological image?" "Round and polygonal" "Cuboidal" "Squamous" "Spindle-shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3493.jpg" -"3494" "Analyzing the cytoplasm of the keratinocytes, which description is most accurate?" "Basophilic and reticular" "Blue-gray and homogeneous" "Pale and vacuolated" "Eosinophilic and granular" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3494.jpg" -"3495" "What is the staining method used to visualize the structures within this connective tissue sample?" "Masson's Trichrome" "Periodic acid-Schiff (PAS)" "Silver stain" "Hematoxylin and eosin (H&E)" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3495.jpg" -"3496" "Based on the morphology of the cells and pigmented granules in the cytoplasm, what might these pigmented granules represent in the context of the image?" "Hemosiderin within macrophages" "Glycogen deposits within hepatocytes" "Lipofuscin within nerve cells" "Melanin within melanocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3496.jpg" -"3497" "Based on the cellular morphology visible within the green circle, what is the most likely identity of the small, round structures with purple-stained nuclei?" "Tubular epithelial cells" "Podocytes" "Glomerular endothelial cells" "Mesangial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3497.jpg" -"3498" "What can be inferred about the morphology of the cells with strong brown nuclear staining when compared to those without staining?" "The cells without staining are smaller and show no pleomorphism" "The cells with staining are smaller with clear halos around the nuclei" "Cells with and without staining are morphologically indistinguishable" "The cells without staining are larger and more pleomorphic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3498.jpg" -"3499" "What histologic feature is observed in the top left quadrant that is commonly associated with bone-forming tumors?" "Irregular spicules of bone" "Psammomatous calcifications" "Lace-like osteoid deposition" "Rosette formations" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3499.jpg" -"3500" "What does the appearance of the stroma in this image suggest?" "Myxoid degeneration due to the presence of loose, watery stroma" "Necrosis due to the darkly stained areas" "Edema due to the clear spaces within the stroma" "Sclerosis due to the densely eosinophilic appearance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3500.jpg" -"3501" "What is the predominant type of cells observed in this tissue sample?" "Cuboidal cells" "Spindle-shaped cells" "Adipocytes" "Squamous cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3501.jpg" -"3502" "What is the predominant cell type visible in this high-power microscopic field of the tissue?" "Monocytes" "Eosinophils" "Lymphocytes" "Neutrophils" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3502.jpg" -"3503" "How would you describe the nuclei of the most numerous cells in this image?" "Bilobed" "Irregular and folded" "Multi-lobulated" "Round with condensed chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3503.jpg" -"3504" "In the left region of the image, what pattern does the smooth muscle tissue exhibit?" "Whorled pattern" "Rosette formation" "Haphazard arrangement" "Nested arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3504.jpg" -"3505" "What is the morphology of the predominant cell type observed in the tissue?" "Spherical with prominent nucleoli" "Columnar with basal nuclei" "Cuboidal with centrally located nuclei" "Spindle-shaped with hyperchromatic nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3505.jpg" -"3506" "Considering the cell morphology and arrangement, what feature is predominating in this tissue section?" "Sarcomatous spindle cell configuration" "Eosinophilic cytoplasm with prominent cell borders" "Signet ring cells with abundant mucin" "Syncytial arrangement of epithelioid cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3506.jpg" -"3507" "Based on the cellular morphology, what phase of the endometrial cycle does this histological section most likely represent?" "Early proliferative phase" "Secretory phase" "Late proliferative phase" "Menstrual phase" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3507.jpg" -"3508" "What does the cellular composition of the stroma suggest about the phase of the menstrual cycle?" "It implies a dense, spindle-shaped cellular constitution typical of the proliferative phase" "It indicates a poor hormonal response" "It points to a decidualization process as seen in pregnancy" "It suggests a post-ovulatory, progesterone-dominated environment" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3508.jpg" -"3509" "How are the nuclei of the multinucleated giant cells arranged within the cell body in this image?" "Positioned at one pole creating a cap-like structure" "Arranged at the periphery creating a horseshoe shape" "Evenly dispersed throughout the cytoplasm" "Clustered in the center of the cell body" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3509.jpg" -"3510" "What can be inferred about the dermal-epidermal junction from the image?" "There is an obscuration of the interface due to the presence of a blister" "It maintains its integrity with no apparent obscurity" "There is acantholysis causing a loss of integrity" "There is a significantly thickened basement membrane" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3510.jpg" -"3511" "When considering the morphology of the stained cells, what observations can be made about their size and shape?" "The cells vary widely in size and shape, suggesting high morphological diversity" "The cells are largely uniform in size and shape, indicating a homogeneous cell population" "The majority of cells appear multinucleated and atypically large, typical of giant cell formations" "The cells are predominantly elongated and spindle-shaped, characteristic of mesenchymal origin" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3511.jpg" -"3512" "What is the predominant type of epithelial cell lining observed at the topmost layer of the tissue section?" "Transitional epithelial cells" "Ciliated epithelial cells" "Squamous epithelial cells" "Columnar epithelial cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3512.jpg" -"3513" "Based on the granular and eosinophilic appearance within the gland-like structures and the presence of cells with dark-staining nuclei, what does the image suggest?" "Normal physiological secretory activity" "Neoplastic proliferation" "Acute inflammatory process" "Chronic inflammatory process" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3513.jpg" -"3514" "Based on the cellular arrangement seen in the image, what pattern is most evident?" "Rosette formation" "Fascicular pattern" "Glandular arrangement" "Sheets of undifferentiated cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3514.jpg" -"3515" "What best describes the nuclear features of the cells present in this tissue section?" "Nuclei with uniform appearance and absence of hyperchromasia" "Presence of atypical mitotic figures" "Significant pleomorphism and hyperchromasia" "Multi-nucleated with varying nuclear sizes and irregular chromatin pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3515.jpg" -"3516" "Is there any evidence of abnormal spindle formation which might suggest aberrant mitotic activity?" "Atypical mitotic figures with multi-spindling" "High mitotic index with numerous abnormal spindle formations" "No evidence of abnormal spindle formation" "Abnormal mitotic figures with irregular spindle formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3516.jpg" -"3517" "What kind of vascular structures can be observed in this liver tissue section?" "Numerous capillaries with evidence of neovascularization" "Larger empty spaces likely representing central veins or hepatic arteries" "Thick-walled arterioles suggestive of arterial hypertension" "Prominent inflammatory cell infiltrate within the vasculature" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3517.jpg" -"3518" "What type of epithelial tissue is visible in the lower portion beneath the striated muscle layer?" "Simple cuboidal epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3518.jpg" -"3519" "Based on the cellular morphology, what is the most likely nature of this tumor?" "Highly anaplastic with numerous mitotic figures" "Markedly pleomorphic with severe nuclear atypia" "Moderate anisocytosis with minimal atypia" "Uniform cells with extensive areas of necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3519.jpg" -"3520" "What structural abnormality is evident within the dermis that suggests a pathological process?" "Abundance of adipose tissue indicative of lipomatous growth" "Uniform collagen bundles without cellular infiltration" "A small, darkly-staining structure consistent with a parasitic organism" "Neutrophils arranged in a granuloma-like formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3520.jpg" -"3521" "How would you describe the cytoplasm of the cells in this tissue section?" "The cytoplasm is eosinophilic and has ill-defined borders" "The cytoplasm is basophilic with well-defined borders" "The cytoplasm has a cleared, vacuolated appearance" "The cytoplasm is amphophilic with a granular texture" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3521.jpg" -"3522" "What does the chromatin distribution within the nuclei of the cells suggest?" "The chromatin pattern suggests hyperactivity and increased mitotic rate" "The nuclei show signs of karyolysis indicative of necrosis" "There is evidence of chromatin condensation, a hallmark of apoptosis" "The chromatin is distributed evenly, indicating viable cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3522.jpg" -"3523" "Based on the cellular morphology observed in the left side of the image, which histological feature is most consistent with the tissue's appearance?" "Uniform cells with eosinophilic cytoplasm and round nucleoli" "Increased mitotic activity and necrosis" "Marked cellular pleomorphism and hyperchromasia" "Dysplastic cells with loss of polarity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3523.jpg" -"3524" "What characteristic can be observed in the tissue towards the center of the image?" "Adenomatous hyperplasia with budding structures" "Dense fibrosis with a lack of cellular structures" "Cystic spaces lined by a thin layer of cells" "Highly cellular stroma with malignant invasion" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3524.jpg" -"3525" "What characteristic of the connective tissue in the dermis can be observed?" "Disorganized matrix pattern" "Complete loss of fibrillar structure" "Extensive fibrosis" "Normal fibrillar matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3525.jpg" -"3526" "What is the status of the inflammatory infiltrate in this histopathological image?" "No significant infiltrate visible" "Granulomatous inflammation" "Dense perivascular infiltrate" "Prominent lymphoid aggregates" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3526.jpg" -"3527" "What does the epidermal layer predominantly exhibit in terms of cellular organization?" "Equally distributed melanocytes throughout the epidermis" "Normal, linear maturation of keratinocytes" "Isolated atypical keratinocytes restricted to the basal layer" "Disorganized pattern of atypical keratinocytes throughout its full thickness" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3527.jpg" -"3528" "What feature can be observed in the stratum corneum of the epidermis?" "Hyperkeratosis with parakeratosis" "Complete absence of keratin" "A normal basket-weave pattern devoid of nuclei" "Uniform thinning and atrophy of the layer" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3528.jpg" -"3529" "In this H&E stained skin tissue section, what is the nature of the multinucleated giant cells?" "Reese giant cells" "Foreign body-type giant cells" "Langhans-type giant cells" "Touton-type giant cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3529.jpg" -"3530" "What histological feature is indicated by the pale staining intracellular material within the epithelial cells?" "Lipid deposits" "Glycogen accumulation" "Keratin accumulation" "Mucin presence" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3530.jpg" -"3531" "Based on the tissue organization, what is the most likely identification of this structure?" "Thyroid gland" "Gastric mucosa" "Respiratory epithelium" "Cystic duct" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3531.jpg" -"3532" "Assessing the chromatin distribution within the nuclei, what can you infer?" "Chromatin is clumped and irregular" "Chromatin is distributed evenly with visible nucleoli" "Chromatin shows a clearing indicative of viral changes" "Chromatin is margination along the nuclear membrane" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3532.jpg" -"3533" "Evaluating the cell population's growth pattern in the image, how would you describe it?" "Disorganized with a sheet-like growth pattern" "Organized into well-defined lobules" "Forming glandular structures" "Organized along a fibrovascular core" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3533.jpg" -"3534" "What histological feature distinguishes the elongated cells in this image?" "Multinucleated cells" "Perinuclear halo" "Cytoplasmic vacuoles" "Central nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3534.jpg" -"3535" "What is indicated by the presence of round to ovoid nuclei amid the elongated cells?" "Sign of benign fatty infiltration" "Normal variation in muscle cell types" "Presence of inflammatory cells" "Indicative of muscle cell regeneration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3535.jpg" -"3536" "Based on the cellular arrangement around the follicular structures, which type of growth pattern is most evident?" "Disordered hyperplasia" "Anaplastic growth" "Neoplastic proliferation" "Regular tissue organization" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3536.jpg" -"3537" "Which red blood cell morphology corresponds with the cell indicated by the dark arrow?" "A sickle cell with elongated crescent shape" "A target cell with central pallor" "A spherocyte lacking central pallor" "An echinocyte with evenly spaced projections" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3537.jpg" -"3538" "What abnormality is indicated by the cell pointed out by the light blue arrow with the inset square?" "Basophilic stippling" "Heinz body" "Pappenheimer body" "Howell-Jolly body" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3538.jpg" -"3539" "Identify the red blood cell morphology indicated by the light blue arrow without the inset square." "A stomatocyte with a single, central, slit-like area of pallor" "An acanthocyte with spicules of varying lengths" "An elliptocyte, typically associated with hereditary elliptocytosis" "A target cell with a bullseye-like appearance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3539.jpg" -"3540" "What characteristic pattern of growth can be identified in the adenocarcinoma shown?" "Trabecular growth pattern" "Syncytial growth pattern" "Solid growth pattern" "Focal papillary pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3540.jpg" -"3541" "In the image, where are the skeletal muscle fibers primarily located?" "In the upper third portion below the serosa layer" "Surrounding the blood vessels within the connective tissue" "Right beneath the stratified squamous epithelium" "Interspersed with the submucosal glands" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3541.jpg" -"3542" "What type of muscle tissue is prominently featured in this cross-sectional image?" "Skeletal muscle" "Cardiac muscle" "Dense irregular connective tissue" "Smooth muscle" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3542.jpg" -"3543" "Identify the characteristic that is not consistent with the muscular tube depicted in this image?" "Concentric layering of the muscle cells" "Longitudinal orientation of the outermost muscle cells" "Striations in the muscle cells" "Presence of a central lumen" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3543.jpg" -"3544" "Based on the observed morphology, what is the likely lining of the lumen in this tissue section?" "Stratified squamous epithelium" "Simple squamous epithelium" "Transitional epithelium" "Pseudostratified columnar epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3544.jpg" -"3545" "What feature in the microscopic image corresponds to what is clinically described as 'seed warts'?" "Prominent inflammatory infiltrate surrounding the glandular structures" "Clusters of basaloid cells with peripheral palisading" "Deeply pigmented melanocytic lesions" "Reddish-pink areas indicative of hemorrhages within the epithelial structures" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3545.jpg" -"3546" "Several cells with multilobed nuclei are visible in this tissue sample. What is the most likely identity of these cells?" "Monocytes" "Eosinophils" "Lymphocytes" "Neutrophils" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3546.jpg" -"3547" "What do the concentrically laminated structures observed in the center left part of the image indicate?" "Psammoma bodies commonly seen in serous cystadenocarcinoma" "Russell bodies typically found in plasma cell neoplasms" "Granulomas associated with a chronic inflammatory process" "Keratin pearls associated with squamous cell carcinoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3547.jpg" -"3548" "Based on the appearance of the nuclei, which term best describes the observed cellular changes?" "Anisokaryosis" "Pyknosis" "Hyperchromatic" "Karyorrhexis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3548.jpg" -"3549" "What type of epithelium lines the irregular luminal spaces within the tissue?" "Pseudostratified columnar epithelium, with unevenly positioned nuclei giving the impression of stratification" "Stratified squamous epithelium, with multiple layers of cells" "Simple squamous epithelium, with a single layer of flattened cells" "Transitional epithelium, with characteristic dome-shaped surface cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3549.jpg" -"3550" "The small, darker-staining structures within the fibromuscular stroma most likely represent:" "Glandular structures with ducts leading to the lumina" "Muscle fibers due to their striated appearance" "Hemorrhagic areas due to the presence of red blood cells" "Nerve bundles due to the appearance of elongated fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3550.jpg" -"3551" "What is the predominant characteristic of the stroma observed in the tissue?" "Loose connective tissue with abundant adipocytes" "Hyaline cartilage with lacunae and chondrocytes" "Hematopoietic bone marrow with various stages of blood cells" "Dense fibromuscular tissue with closely packed fibers" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3551.jpg" -"3552" "What cell type dominates the field in this histological sample?" "Osteocytes" "Fibroblasts" "Adipocytes" "Chondrocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3552.jpg" -"3553" "Based on the morphology of the cells and intercellular matrix, what is the likely function of the dense connective tissue displayed in this section?" "Providing strength and flexibility along lines of tension" "Resistance to multidirectional tensile forces" "Storage of energy" "Support and protection of body organs" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3553.jpg" -"3554" "What type of connective tissue is primarily observed in this histological section?" "Dense irregular connective tissue" "Elastic connective tissue" "Loose connective tissue" "Dense regular connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3554.jpg" -"3555" "Based on the microscopic features observable in the image, what type of epithelium lines the cystic structure?" "Columnar epithelium" "Squamous epithelium" "Cuboidal epithelium" "Transitional epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3555.jpg" -"3556" "The peripheral structures of the glandular tissue are indicative of what kind of secretion based on the morphological appearance?" "Seromucinous secretion, with both serous and mucinous components mixed" "Serous secretion, with clearly discernible zymogen granules" "Mucinous secretion, with evidence of mucin within the acini" "Sebaceous secretion, with lipid droplets present in the tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3556.jpg" -"3557" "What is the predominant feature of the cytoplasm observed in the cells within this tissue section?" "Extensive rough endoplasmic reticulum distribution" "Numerous mitochondria visible throughout the cytoplasm" "Abundance of granular eosinophilic material" "Presence of a large, clear cytoplasmic vacuole" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3557.jpg" -"3558" "What is the dominant morphology of the endothelial cells lining the channels in this tissue section?" "Uniformly shaped with clear cytoplasm" "Mostly uniform, small and round cells" "A mix of epithelioid and spindle-shaped cells with atypia" "Spindle-shaped with uniform nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3558.jpg" -"3559" "In the histopathological image, is there evidence of normal vascular function within the channels?" "Yes, because the presence of occasional erythrocytes indicates some degree of vascular differentiation" "No, because erythrocytes are abnormal in shape and size" "No, because the channels are mostly occluded and do not transport erythrocytes" "Yes, because erythrocytes are regularly organized within the channels" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3559.jpg" -"3560" "How would you characterize the stroma surrounding the diagnostic cells in this image?" "Highly cellular with well-defined boundaries" "Mixed cellularity with indistinct cellular structures" "Dominated by fibroblastic proliferation" "Acellular with significant hyalinization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3560.jpg" -"3561" "Based on the microscopic appearance of the nuclei in the muscle tissue, how would you characterize their location within the cells?" "Nuclei are centrally located within the fibers" "Nuclei are absent from the cells" "Nuclei are inconsistently distributed throughout the cells" "Nuclei are located at the periphery of the cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3561.jpg" -"3562" "What feature is characteristic of the large clear vacuoles within hepatocytes as seen in this image?" "Microvesicular steatosis" "Hydropic degeneration" "Glycogen storage" "Macrovesicular steatosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3562.jpg" -"3563" "Based on this image, what feature supports the idea that this liver tissue may be part of a hepatocellular carcinoma (HCC) with a steatohepatitic pattern?" "Absence of portal tracts" "Presence of typical portal tracts" "Predominance of microvesicular steatosis" "Isolation of bile ducts without accompanying vessels" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3563.jpg" -"3564" "Identify the histological feature labeled by the arrow in the image." "Lipogranuloma" "Megamitochondria" "Acidophil bodies" "Mallory-Denk bodies" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3564.jpg" -"3565" "How would you describe the central cells within the follicular structures in terms of density and arrangement?" "Densely packed with a high nucleus-to-cytoplasm ratio" "Loosely arranged with lower cell density" "Organized in a glandular rosette pattern" "Arranged in tightly packed nests with desmoplastic stroma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3565.jpg" -"3566" "Based on the arrangement of the cells within the matrix, how would you describe the growth pattern?" "Palisading" "Haphazard and disorganized" "Organized and uniform" "Circular and whorled" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3566.jpg" -"3567" "What tissue component might be challenging to definitively identify in this image without specific staining?" "Elastic fibers" "Nerve fibers" "Collagen fibers" "Blood vessels" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3567.jpg" -"3568" "Based on the morphology of the nuclei, how would you describe their appearance?" "Round and uniform" "Hyperchromatic and pleomorphic" "Small with prominent nucleoli" "Elongated and somewhat wavy or corkscrew-shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3568.jpg" -"3569" "The lighter, eosinophilic areas interspersed throughout the tissue section could be indicative of which of the following structures or components?" "Dense connective tissue" "Cytoplasmic contents" "Hyalinized stroma" "Calcifications" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3569.jpg" -"3570" "What is the morphological appearance of the cells in the epidermis just below the stratum corneum?" "The cells show nuclear atypia." "The cells display a loss of nuclear material." "The cells demonstrate multinucleation." "The cells appear smaller than the basal layer cells." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3570.jpg" -"3571" "How would you describe the organization of the spindle cells in this tissue?" "Disorganized" "Forming glandular structures" "Organized in nests" "Arranged around a central lumen" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3571.jpg" -"3572" "Based on the image, what can be said about the blood vessel walls within the tissue?" "They are thin and delicate" "They are highly vascularized with numerous small vessels" "They exhibit marked hyalinization" "They contain a prominent inflammatory infiltrate" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3572.jpg" -"3573" "Assessing the extracellular matrix in this histological section, what can be deduced from the staining characteristics?" "Eosinophilic stroma indicative of a well-vascularized lesion" "Acidophilic extracellular matrix suggestive of osteoid production" "Eosinophilic extracellular matrix which has taken up the eosin stain" "Dense collagen deposition consistent with fibrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3573.jpg" -"3574" "Which structural feature is characteristic of the fungal elements that can be observed in this tissue sample?" "Broad-based budding" "Varying size and pigmentation" "Uniform septation" "Spore formation within spherules" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3574.jpg" -"3575" "What is a distinguishing histological feature of the nuclei in the RB1+/+ tumor sample?" "Round or oval nuclei with prominent singular nucleoli" "Multilobed nuclei with inconspicuous nucleoli" "Nuclei contain multiple, darkly staining nucleoli" "Nuclei appear wrinkled with no visible nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3575.jpg" -"3576" "What additional histopathological feature can be observed interspersed among the melanocytes?" "Melanin pigment" "Necrotic debris" "Multinucleated giant cells" "Lipid vacuoles" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3576.jpg" -"3577" "Assessing the nuclear features of the melanocytes, what type of pleomorphism is present?" "No significant pleomorphism" "Moderate nuclear and cellular pleomorphism" "Severe nuclear pleomorphism with significant anisokaryosis" "Mild nuclear pleomorphism" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3577.jpg" -"3578" "What layer of skin tissue exhibits a bright pink coloration due to a thick layer of eosinophilic material?" "Stratum spinosum" "Dermis" "Stratum granulosum" "Stratum corneum" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3578.jpg" -"3579" "Based on the image, what could likely be the pathology within the epidermis?" "Acute spongiosis" "Acantholysis" "Epidermolytic hyperkeratosis" "Psoriatic hyperplasia" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3579.jpg" -"3580" "What type of cellular morphology is predominantly observed in the inflammatory rim surrounding the central crystalline structures?" "Epithelioid histiocytes" "Lymphocytes" "Multinucleated giant cells" "Neutrophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3580.jpg" -"3581" "What is the morphology of the crystalline structures present in the central focus?" "Laminar, basophilic layers" "Granular, eosinophilic clusters" "Amorphous, translucent and needle-like" "Round, opaque structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3581.jpg" -"3582" "Based on the pathology presented in the image, what feature of the extracellular matrix is notable in the region surrounding the inflammatory zone?" "Homogeneous, eosinophilic staining" "Disorganized, hyalinized appearance" "Extensive necrosis" "Homogeneous, basophilic staining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3582.jpg" -"3583" "What can be inferred about the nuclear-to-cytoplasmic ratio within the cell clusters depicted in this image?" "The nuclear-to-cytoplasmic ratio is high" "The nuclear and cytoplasmic components are equally distributed" "The nuclear-to-cytoplasmic ratio is indeterminable" "The nuclear-to-cytoplasmic ratio is low" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3583.jpg" -"3584" "In the microscopic view of this tissue, how would you characterize the glandular architecture?" "Regular and well-organized" "Highly complex with branching and budding" "Presence of numerous mitotic figures" "Marked architectural atypia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3584.jpg" -"3585" "What can be inferred about the cellular activity within the glands based on the presence of mitotic figures and nuclear atypia?" "Abnormal and dysregulated growth patterns" "Quiescence with low proliferative activity" "Presence of widespread cellular necrosis" "High level of cellular turnover and proliferation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3585.jpg" -"3586" "What do the glandular structures seen in this image most likely represent?" "Tubular glands of the large intestine" "Eccrine sweat glands" "Sebaceous glands" "Gastric pits of the stomach" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3586.jpg" -"3587" "What is the likely function of the folds of mucosa seen in the image?" "To facilitate expansion and storage of waste in the large intestine" "To produce digestive enzymes for food breakdown" "To protect the stomach lining from acidic environment" "To increase the absorptive surface area in the small intestine" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3587.jpg" -"3588" "Which type of abnormal erythrocyte morphology is NOT prominently visible in the given microscopic image?" "Schistocytes" "Stomatocytes" "Sickle cells" "Target cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3588.jpg" -"3589" "Based on the morphology presented in this slide, how would you describe the nuclei of the follicular cells within the thyroid gland?" "Vesicular with prominent nucleoli" "Hyperchromatic and pleomorphic" "Large with multiple nucleoli" "Basally located with visible nucleoli" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3589.jpg" -"3590" "Based on the architecture and composition of the tissue, what is the arrangement of cells within this sample?" "Organized in well-delineated tubules" "Geometrically in a palisading formation" "Arranged in clusters with indistinct borders" "Isolated and scattered without a pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3590.jpg" -"3591" "What histopathological feature could be highlighted by the broadened septa with increased cellularity within this tissue section?" "Fat necrosis" "Acute inflammation" "Fibrosis" "Chronic inflammation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3591.jpg" -"3592" "What is the morphology of the nuclei of the large cells with purple granules in the image?" "Non-nucleated" "Mononuclear" "Bilobed" "Multilobed" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3592.jpg" -"3593" "What specific tissue characteristic can be observed in the histological image provided?" "The presence of multilocular adipocytes" "The extracellular matrix lacks any fibrous components" "The adipocytes are predominantly unilocular" "Nuclei are centralized within the adipocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3593.jpg" -"3594" "What tissue architecture is observed in terms of the rete ridges of the epidermis in the provided histological image?" "Branched and irregular" "Thinned and fragmented" "Shortened and effaced" "Elongated and club-shaped" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3594.jpg" -"3595" "The architecture of the neoplasm in the image most likely suggests which of the following?" "Malignant melanoma" "Basal cell carcinoma" "Squamous cell carcinoma" "Sebaceous adenoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3595.jpg" -"3596" "Based on the staining pattern, what type of tissue compartment might the denser and more homogeneous area beneath the elongated projections represent?" "Hyalinized connective tissue often seen in fibrotic processes" "Cartilaginous tissue with chondrocytes in lacunae" "Adipose tissue with large lipid vacuoles" "Lamina propria with connective tissue characteristics" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3596.jpg" -"3597" "Based on the histological patterns observed, which of the following best describes the arrangement of the cells?" "Uniform cells arranged in acini" "Nests of pleomorphic cells" "Palisading nuclei around a central fibrovascular core" "Whorled pattern of spindle cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3597.jpg" -"3598" "What abnormal feature can be observed in the glandular structures seen in the microscopic image of the gastrointestinal tract tissue?" "Crypts running parallel to the mucosal surface" "Absence of inflammatory cells within the lamina propria" "Uniform crypt size and shape" "Regular distribution of crypts without distortion" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3598.jpg" -"3599" "Based on the observed crypt architecture in the image, which feature is least likely to be associated with a diagnosis of inflammatory bowel disease?" "Intact crypt architecture" "Presence of chronic inflammatory infiltrate" "Disrupted epithelial layer" "Continuous damage throughout the mucosa" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3599.jpg" -"3600" "The vascular channels in this tissue section lack certain internal structures. What is missing from these vessels that would be expected in normal vasculature?" "Pericytes along the vessel walls" "Erythrocytes within the lumen" "Prominent internal lamina" "Endothelial cells lining the vessels" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3600.jpg" -"3601" "Based on the image, how would you describe the architectural pattern of the nests of melanocytes?" "The nests present with uniform maturation and diminution in cell size and pigmentation at deeper levels" "The nests show a lack of maturation as they extend into the deeper dermis" "The nests exhibit even distribution and uniform cell size throughout the dermis" "The nests are absent, with melanocytes evenly dispersed throughout the dermis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3601.jpg" -"3602" "What characteristic feature of the melanocytes at the dermoepidermal junction can be noted in this image?" "The melanocytes exhibit multinucleation with little cytoplasmic melanin" "The melanocytes appear large with abundant eosinophilic cytoplasm" "The melanocytes are uniformly small with sparse cytoplasm" "The melanocytes are small with hyperchromatic nuclei and no visible cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3602.jpg" -"3603" "Based on the cellular morphology seen in this tissue sample, what is not observed that might suggest a more aggressive pathology?" "Uniformity in the density and orientation of the cells" "Presence of keratin-filled cysts" "Hyperchromatic nuclei" "Well-defined rounded structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3603.jpg" -"3604" "Which of the following best describes the darker region with a dense aggregate of nuclei observed in the lower right corner of the image?" "Fat necrosis with lipid-laden macrophages" "Dense collagen deposition with minimal cellularity" "Region of active fibroblasts or myofibroblasts suggesting tissue remodeling" "Acute inflammatory infiltrate with a predominance of neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3604.jpg" -"3605" "What is the primary morphological feature observed in the epithelium of this tissue sample?" "Spongiosis" "Parakeratosis" "Acantholysis" "Hyperkeratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3605.jpg" -"3606" "Based on the tissue architecture and cellular morphology, what is the most likely origin of the cells in this image?" "Endothelial origin, based on the structured pattern of cells" "Epithelial origin, based on the presence of glandular structures" "Neural origin, based on the presence of ganglion-like cells" "Mesenchymal origin, based on spindle-shaped features" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3606.jpg" -"3607" "Based on the arrangement of cells, where can blood vessels likely be observed in this image?" "Within the dense fibroblastic proliferation on the left" "Adjacent to the spindle-shaped cells of the left side" "In the area with a collagen-rich extracellular matrix" "Within the inflamed tissue on the right side showing a looser matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3607.jpg" -"3608" "Analyzing this image, which feature is absent that would otherwise suggest a more aggressive neoplastic process?" "Highly pleomorphic cells" "Abundant areas of necrosis" "Lack of significant nuclear atypia" "Presence of gland-like structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3608.jpg" -"3609" "What is the predominant extracellular matrix composition of the stroma observed in this histological section?" "Myxoid matrix" "Dense collagen bundles" "Hyaline cartilage" "Adipose tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3609.jpg" -"3610" "Based on the arrangement of vascular structures, how would you classify the organization of the vessels within this tissue?" "Organized in a 'chicken wire' pattern" "Randomly dispersed without a discernible pattern" "Delicately branching in a non-uniform pattern" "Forming thick-walled, muscular structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3610.jpg" -"3611" "Which of these findings in the tissue shown would be indicative of a normal aging process?" "Eosinophilic cytoplasmic inclusions" "Rarefaction of myofibrils" "Interruption of striations" "Enlarged nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3611.jpg" -"3612" "In the context of squamous cell carcinomas, which of the following cellular features is NOT typically consistent with a malignant process?" "Lack of desmosomal connections" "Keratinization with a lack of nuclei" "Presence of small, dense nuclei" "Cells with intensely eosinophilic cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3612.jpg" -"3613" "Based on the eosinophilic areas observed in the image, which type of cells are predominantly present within this tissue section?" "Hepatocytes" "Keratinocytes" "Neutrophils" "Lymphocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3613.jpg" -"3614" "Based on the arrangement and morphology of the spindle-shaped cells, which pattern is NOT observed in this tissue section?" "Cells arranged in short fascicles" "Cells arranged in a storiform pattern" "Cells forming whorls" "Cells arranged in a herringbone pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3614.jpg" -"3615" "What feature is prominently observed in the nuclei of the cells within this tissue section?" "Clear nuclei with prominent nucleoli" "Monomorphic nuclei with uniform size and shape" "Small, inconspicuous nuclei" "Hyperchromatic nuclei with dense staining" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3615.jpg" -"3616" "What feature distinguishes type 2 pneumocytes from type 1 pneumocytes in this image?" "Their larger size and cuboidal shape" "Their flattened shape and widespread coverage" "Their location lining the bronchioles" "Their ability to engulf bacteria" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3616.jpg" -"3617" "How would you describe the nuclei of the glandular epithelial cells in this tissue section?" "Vesicular with multiple nucleoli" "Basally located and uniform" "Enlarged with prominent nucleoli" "Hyperchromatic and pleomorphic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3617.jpg" -"3618" "Analyzing the image, what histological feature best describes the papillary dermis?" "Presence of dense, irregular connective tissue" "Pale with reduced cellular and fibrous components" "Predominantly composed of adipose tissue" "Highly vascularized with abundant fibroblasts" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3618.jpg" -"3619" "Based on the appearance of the nuclei, how would you describe their chromatin pattern?" "Euchromatic with multiple nucleoli" "Hyperchromatic without visible nucleoli" "Hypochromatic with prominent nucleoli" "Vesicular with large nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3619.jpg" -"3620" "What is the predominant staining characteristic of the extracellular material in the tissue sample?" "Neutrophilic - neutral/pale staining" "Basophilic - blue/purple staining" "Acidophilic - reddish/pink staining" "Chromophobic - lack of staining" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3620.jpg" -"3621" "What cytoplasmic staining character is dominantly visible within the islets of Langerhans?" "Basophilic with a blue hue and rich in RNA" "Eosinophilic with a pink hue and protein-rich" "Neutrophilic with no significant staining" "Amphophilic with both pink and blue hue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3621.jpg" -"3622" "In the circled area, what is the predominant morphological feature of the large cells observed?" "Abundant vacuolated cytoplasm" "Multinucleation with dense eosinophilic cytoplasm" "Spindle-shaped cells with hyperchromatic nuclei" "Single nucleus with clear perinuclear halo" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3622.jpg" -"3623" "What does the presence of brightly eosinophilic and homogeneous areas in the image most likely indicate?" "Hypercellularity due to leukocyte infiltration" "Minimal change disease" "Fibrinoid necrosis" "Amyloidosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3623.jpg" -"3624" "Based on the histological features observed in the image, what pattern of inflammation is indicated by the presence of numerous cells with denser nuclei in the dermis?" "Eosinophilic inflammation" "Suppurative inflammation" "Granulomatous inflammation" "Lymphocytic inflammation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3624.jpg" -"3625" "Which type of cells are suggested to be Sertoli cells in the tissue based on their nuclear characteristics?" "Cells with large, dense, and round nuclei" "Cells with smaller, darker staining nuclei that are irregular in shape" "Cells with round and open nuclei with lighter chromatin" "Cells with uniform shapes and intensely stained nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3625.jpg" -"3626" "Which type of cells, based on the morphology and staining characteristic observed in the image, likely represent cells in the prophase stage of meiosis?" "Cells with prominent size and lighter staining nuclei" "Cells with smaller, lightly stained round nuclei" "Cells with large, darkly stained irregular nuclei" "Cells with high density of cytoplasm and no visible nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3626.jpg" -"3627" "Based on the distribution of glomeruli within the renal cortex, how would you describe their appearance in this histopathological image?" "Evenly distributed without any signs of sclerosis" "Predominantly located at the corticomedullary junction" "Clustered together, indicating possible glomerular hyperfiltration" "Irregularly scattered with signs of glomerulosclerosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3627.jpg" -"3628" "Based on the histological analysis, what is the condition of the stratum corneum?" "It shows parakeratosis with retained nuclei in the stratum corneum." "It is well-formed and compact." "There is evidence of hyperkeratosis with increased thickness." "It appears hypoplastic with reduced thickness." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3628.jpg" -"3629" "Based on the histopathologic features shown, what does the area with more uniform, pink-staining cells likely represent?" "Striated skeletal muscle undergoing regeneration" "Hepatocytes exhibiting ballooning degeneration" "Preserved cardiac muscle fibers with contraction bands" "Normal renal tubules with eosinophilic brush border" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3629.jpg" -"3630" "What cellular feature is indicated by the arrow in the image?" "Single nucleated lymphocyte" "Eosinophil infiltration" "Multinucleated giant cell" "Binucleated cell" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3630.jpg" -"3631" "What characteristic feature does the largest cell in the center of this image display?" "A single, well-defined nucleus" "Multiple nuclei with variation in size and staining" "Absence of cytoplasm" "Uniformly small, hyperchromatic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3631.jpg" -"3632" "Considering the surrounding cells' nuclear features, which description is accurate?" "The nuclei are small, uniform, and well-differentiated" "The nuclei are multinucleated and show a high degree of organization" "The nuclei appear singular with some pleomorphism and hyperchromatic characteristics" "The nuclei are large, with a conspicuous nucleoli and minimal pleomorphism" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3632.jpg" -"3633" "In the provided microscopic image of the epithelial tissue, what is the predominant feature observed within the cytoplasm of several epithelial cells?" "Large, irregularly shaped nuclei" "Uniform eosinophilic staining throughout the cells" "Presence of multiple, prominent nucleoli" "Clear spaces indicative of vacuolation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3633.jpg" -"3634" "What other tissue interaction is noted in this microscopic image?" "Lymphocytic infiltration in cartilage" "Hyalinization of connective tissue surrounding cartilage" "Necrotic adipose tissue near cartilage" "Reddish bony trabeculae intersecting cartilage" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3634.jpg" -"3635" "What is the nature of the nuclei within the chondrocytes in this microscopic image?" "The nuclei are hyperchromatic with a coarse chromatin pattern" "The nuclei exhibit pleomorphism" "The nuclei present with multiple prominent nucleoli" "The nuclei are small and uniform" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3635.jpg" -"3636" "What is the predominant epithelial cell type lining the tubular structures in this tissue sample?" "Transitional epithelium" "Columnar epithelium" "Cuboidal epithelium" "Squamous epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3636.jpg" -"3637" "Based on the cellular composition of the stroma, what type of connective tissue is likely supporting the glandular structures?" "Dense irregular connective tissue" "Loose connective tissue" "Hyaline cartilage" "Adipose tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3637.jpg" -"3638" "Based on the appearance of the cells' cytoplasm, how would you characterize it?" "Granular cytoplasm with multiple inclusions" "Abundant clear cytoplasm" "Dense eosinophilic cytoplasm" "Scarce basophilic cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3638.jpg" -"3639" "Based on the staining pattern observed in the image, what describes the condition of mitochondrial activity in the tissue?" "All muscle fibers show absence of enzymatic activity" "Most muscle fibers indicate a loss of succinate dehydrogenase activity" "Muscle fibers uniformly lack mitochondrial aggregates or pathological changes" "Most muscle fibers display preserved succinate dehydrogenase activity" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3639.jpg" -"3640" "What characteristic feature of the nuclei in this tissue section suggests a high level of mitotic activity?" "Uniform chromatin distribution" "Multiple nucleoli within the nuclei" "One single prominent nucleolus" "Hyperchromatic nuclei with irregular chromatin condensation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3640.jpg" -"3641" "Upon examination of the tissue, the absence of which feature would argue against a diagnosis of a more aggressive lymphoma?" "Presence of macrophages" "Large transformed cells" "Conspicuous mitotic figures" "Significant cellular pleomorphism" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3641.jpg" -"3642" "Based on the cellular morphology, what type of epithelial tissue is observed in the uppermost layer of the image?" "Simple columnar epithelium" "Stratified squamous epithelium" "Simple squamous epithelium" "Pseudostratified columnar epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3642.jpg" -"3643" "Based on the tissue morphology, what type of cellular atypia is evident in the microscopic image?" "Cytoplasmic vacuolization" "Anisonucleosis" "Nuclear hyperchromasia" "Presence of microcalcifications" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3643.jpg" -"3644" "What type of cellular morphology is predominantly featured in this skin tissue sample?" "Signet ring cells with eccentric nuclei" "Spindle-shaped cells with elongated nuclei" "Squamous cells with distinct intercellular bridges" "Polygonal cells with hyperchromatic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3644.jpg" -"3645" "Based on the visible structures, which adnexal components are likely observed in this skin tissue section?" "Sebaceous glands" "Eccrine sweat glands" "Apocrine sweat glands" "Meissner's corpuscles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3645.jpg" -"3646" "In the stromal component, what type of vacuoles can be observed?" "Mucin-filled vacuoles" "Keratin-filled vacuoles" "Erythrocyte-filled vacuoles" "Clear lipid vacuoles" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3646.jpg" -"3647" "How does the inflammatory response appear within the stromal component?" "Extensive with granulomatous inflammation" "Abundant with neutrophil infiltration" "Minimal with no abundant inflammatory infiltrate" "Moderate with lymphocytic infiltration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3647.jpg" -"3648" "Which cellular arrangement can be observed in this image?" "Spindle-shaped cells forming storiform patterns" "Syncytial arrangement with indistinct cell borders" "Dyscohesive cells with high mitotic activity" "Glandular formation with mucin production" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3648.jpg" -"3649" "What type of nuclear features are predominant in the cells of this histological image?" "Nuclei with prominent pseudo-inclusions" "Multilobulated nuclei with smudging" "Open chromatin with multiple nucleoli" "Hyperchromatic nuclei with irregular contours" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3649.jpg" -"3650" "Identify the specific eosinophilic structure within the cytoplasm of these cells." "Cytoplasmic inclusion bodies associated with viral infections" "Rosette formations indicative of neuroendocrine differentiation" "Eosinophilic granules indicating secretory activity" "Whorl-like formations reminiscent of somatostatin bodies" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3650.jpg" -"3651" "Identifying the layer that likely represents the dentine matrix, what feature distinguishes it from the adjacent enamel matrix?" "The change in color intensity from the adjacent layer" "The regular arrangement of columnar epithelial cells" "The acellular structure with scalloped edges" "The presence of elongated nuclei within the cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3651.jpg" -"3652" "Based on the characteristics visible in this image of stratified squamous epithelium, which feature indicates a process of abnormal premature keratinization?" "Presence of cells with dense, pyknotic nuclei in the upper layers" "Uniformity of basal cell layer" "Retained cell nuclei in superficial layers" "Progressive maturation of keratinocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3652.jpg" -"3653" "What distinctive cellular morphology can be observed in the highlighted cells within this tissue section?" "Signet ring appearance" "Spindle-shaped cells" "Keratin pearl formation" "Multinucleation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3653.jpg" -"3654" "Based on the staining characteristics visible in the image, which structures are likely to be the axons or axon hillocks among the surrounding tissue?" "The structures with a granular texture" "The lighter colored structures" "The structures with the most intense dark staining" "The regions corresponding to empty spaces" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3654.jpg" -"3655" "What can be inferred about the cytoplasm of the cells surrounding the vascular structures?" "Amphophilic staining indicating moderate levels of proteins and nucleic acids" "Eosinophilic, indicating a protein-rich cytoplasm" "Lacks cytoplasmic content, rendering the cells clear or transparent" "Basophilic staining indicating nucleic acid richness" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3655.jpg" -"3656" "What morphological features of the endothelial cells are visible in the image?" "Squamous morphology with thin lining" "Flattened with elongated nuclei" "High cuboidal morphology with prominent nuclei" "Spindle-shaped with inconspicuous nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3656.jpg" -"3657" "Based on the characteristics of the lymphoid tissue visible, where is this tissue most likely located?" "Germinal center of a lymph node" "Medullary sinus of a lymph node" "Para follicular region of a lymph node" "Mantle zone of a lymph node" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3657.jpg" -"3658" "In the histological image provided, what does the central clear and homogeneous space within the circular to oval structures most likely represent?" "Blood vessel lumen" "Luminal space of a glandular acinus" "Luminal space of a hair follicle" "Inner medulla of a lymph node" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3658.jpg" -"3659" "Based on the histological section of the skin tissue shown, what is the most likely nature of the cellular arrangement in the dermis?" "Sparse and regularly distributed fibroblasts" "Uniform adipocytes with clear separation from the dermis" "Abundant collagen bundles with minimal cellular infiltrate" "Dense aggregates of inflammatory cells forming a granulomatous reaction" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3659.jpg" -"3660" "Based on the histological features observed, what type of tissue is displayed in this microscopic image?" "Muscle tissue" "Bone marrow tissue" "Hepatic tissue" "Adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3660.jpg" -"3661" "What features distinguish the epithelial cells lining the upper part of the image?" "Single layer of cube-like cells" "Multiple layers of flattened cells" "Stratification with keratinization" "Single layer of tall columnar cells with microvilli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3661.jpg" -"3662" "Within the epidermal layer and the dermoepidermal junction, we see structures that are indicative of:" "Granulomatous inflammation" "Spongiosis" "Melanocytic proliferation" "Interface dermatitis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3662.jpg" -"3663" "Considering the overall architecture of the lesion, what is the most likely biological behavior suggested by this histological pattern?" "High likelihood of metastatic potential" "Benign process due to lack of significant pleomorphism" "Indicative of chronic inflammation with active fibrosis" "Evidence of dysplasia suggesting pre-neoplastic changes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3663.jpg" -"3664" "Based on the image, which of the following morphologic features are characteristic of the state of differentiation of these cells?" "High nuclear-cytoplasmic ratios" "Monomorphic cell population" "Uniform cell size and shape" "Well-organized tissue architecture" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3664.jpg" -"3665" "What feature is most prominent in the papillary dermis as seen in this histopathological image?" "Edema" "Acanthosis" "Hyperkeratosis" "Fibrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3665.jpg" -"3666" "In the provided histopathological image of skin tissue, what characteristic feature can be observed in the epidermis?" "Spongiosis" "Hypergranulosis" "Dyskeratosis" "Acantholysis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3666.jpg" -"3667" "Based on the organized cellular structure and layers, which type of epithelium is likely depicted in the image?" "Simple squamous epithelium" "Simple cuboidal epithelium" "Stratified cuboidal epithelium" "Stratified squamous epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3667.jpg" -"3668" "Considering the presence of densely packed cell areas within the connective tissue shown in the image, what is the most likely function of these structures?" "Sensation and nerve impulse transmission" "Structural support" "Secretion" "Contraction and movement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3668.jpg" -"3669" "Assessing the border between the two differing tissue areas, what can be inferred about the lesion?" "There is a fibrotic capsule separating the two tissue types" "The transition zone between the two areas shows a gradual shift from normal to atypical cells" "A sharp, clear demarcation exists between the differentiated and dysplastic areas" "The boundary is irregular without a clear demarcation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3669.jpg" -"3670" "What type of epithelium is depicted in this microscopic image?" "Simple columnar epithelium" "Stratified squamous epithelium" "Simple squamous epithelium" "Stratified columnar epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3670.jpg" -"3671" "What does the blue staining component of the tissue most likely represent, based on its distribution and intensity?" "Neural tissue" "Muscular tissue" "Cartilaginous tissue" "Adipose tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3671.jpg" -"3672" "What is the most likely identity of the large clear spaces within the tissue observed in the image?" "Adipocytes in adipose tissue" "Lipid vacuoles within hepatocytes" "Clear cell renal carcinoma cells" "Mucin-filled cysts" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3672.jpg" -"3673" "The focal area with deep purple staining surrounded by reddish-pink extracellular material suggests which of the following pathological changes?" "Necrosis" "Calcification" "Amyloid deposition" "Hemorrhage" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3673.jpg" -"3674" "Based on the histological features observable in this image, what can be inferred about the uniformity of the glandular architecture?" "The glandular architecture lacks uniformity, with irregular shapes and arrangements" "The glands show slight variation but maintain basic structural integrity" "The glandular architecture exhibits a high degree of uniformity and organization" "The glandular architecture demonstrates a regular, repeating pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3674.jpg" -"3675" "Considering the density of stromal tissue and presence of inflammatory cells, what could this suggest about the sample?" "It suggests chronic inflammatory bowel disease." "The sample is likely from osteoarthritic synovium." "There is evidence of acute appendicitis." "These features are common in viral myocarditis." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3675.jpg" -"3676" "Based on the mitotic figures observed, how would you classify the mitotic activity in this tissue?" "Absence of mitotic figures" "Rare and normal mitotic figures" "Frequent but all regular forms" "Frequent with abnormal features" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3676.jpg" -"3677" "Based on the arrangement and appearance of the pink-stained structures in this H&E stained image, what is the most likely histological composition of these structures?" "Myelinated nerve fibers" "Striated muscle fibers" "Collagen bundles" "Elastic fibers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3677.jpg" -"3678" "Identify the cytoplasmic characteristic that predominates in the cells in this image." "Clear cytoplasm with signet-ring like features" "Basophilic cytoplasm with distinct cytoplasmic borders" "Amphophilic cytoplasm with prominent granules" "Eosinophilic cytoplasm that is not readily distinguished" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3678.jpg" -"3679" "In evaluating the rete ridges in this skin biopsy, what pattern do they display?" "The rete ridges are highly irregular with varying lengths and thicknesses" "The rete ridges show marked shortening and effacement throughout the section" "The rete ridges appear long with a degree of uniformity in their length" "The rete ridges are replaced by melanocytic nests, indicative of melanoma" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3679.jpg" -"3680" "Regarding the extracellular matrix observed in this tissue sample, what best characterizes the matrix that the cells are embedded within?" "Lightly eosinophilic myxoid stroma" "Dense eosinophilic fibrillary matrix" "Hyalinized acellular stroma" "Fibrous stroma with densely packed collagen" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3680.jpg" -"3681" "The predominant cell type in this tissue sample is characterized by what morphology?" "Round and densely packed" "Small and spindle-shaped" "Multinucleated giant cells" "Flattened and elongated" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3681.jpg" -"3682" "What is the predominant growth pattern observed in the glandular structures within the tissue?" "Solid" "Papillary" "Cribriform" "Tubular" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3682.jpg" -"3683" "What is the predominant architectural feature observed in the glands within the hyperplastic nodule?" "Atrophic glands with flattening of the epithelial lining" "Simple tubular glands with a single layer of epithelial cells" "Cystically dilated glands with thin-walled structures" "Complex glands with papillary projections and luminal undulations" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3683.jpg" -"3684" "How would the epithelial lining of the glands be best described based on the observed histology?" "Monolayered and composed of atrophic epithelium" "Composed of a disorganized, anaplastic cellular arrangement" "Lined by pseudostratified columnar epithelium" "Characterized by hyperplasia with multiple epithelial layers" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3684.jpg" -"3685" "Based on the staining characteristics and tissue morphology observed in the image, which of the following best describes the predominant matrix material?" "Basophilic cartilaginous tissue" "Necrotic tissue with karyorrhexis" "Eosinophilic fibrous connective tissue" "Acidophilic muscle tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3685.jpg" -"3686" "What best describes the concretions observed within the lumens of several glands?" "Psammoma bodies" "Corpora amylacea" "Keratin pearls" "Necrotic debris" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3686.jpg" -"3687" "Observing the center of the epithelial aggregates, what is the appearance of the cellular arrangement?" "Cells are evenly distributed with minimal atypia" "Cells exhibit a swirling, whorled pattern" "Cells present with more irregular shapes and variable sizes" "Cells show uniform size, shape, and orientation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3687.jpg" -"3688" "What can be inferred about the nuclei of the epithelial cells lining the glandular structures?" "The nuclei are uniform in size with even distribution." "The nuclei display a high degree of pleomorphism." "The nuclei are generally small with a low nuclear to cytoplasmic ratio." "All nuclei show a single prominent nucleolus." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3688.jpg" -"3689" "Based on the organization and special features of the cells seen in the image, what is the most likely function of this tissue?" "Sensory reception" "Absorption and secretion" "Contraction and movement" "Structural support" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3689.jpg" -"3690" "Upon close examination of the chromatin within the nuclei in the marked area, which nuclear feature is most consistently visible?" "Chromatin clumping" "Chromatin clearing" "Nucleolar prominence" "Chromatin margination" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3690.jpg" -"3691" "The brown pigmentation observed in the tissue is consistent with which of the hypothetical explanations provided?" "Excessive iron deposition, indicating hemochromatosis" "Accumulation of hemosiderin, suggesting previous bleeding" "Presence of melanin, indicating melanocytic origin" "Artefactual deposition of staining pigment" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3691.jpg" -"3692" "What is the likely nature of the material observed within the lumen of the cyst-like structure?" "Erythrocytes indicating a hemorrhagic process" "Mucin or other secretions typical of a true cyst" "Calcium deposits characteristic of dystrophic calcification" "Keratin indicative of epidermoid cyst" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3692.jpg" -"3693" "Based on the microscopic features of the tissue, what type of epithelial cell arrangement is most prominent in the image?" "Pseudostratified columnar epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Transitional epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3693.jpg" -"3694" "Focusing on the cells lining the space that may represent the lumen of a cyst, which cellular morphology predominates near the luminal-side?" "Spindle-shaped" "Squamous" "Cuboidal" "Columnar" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3694.jpg" -"3695" "Considering the lack of visible underlying structures beneath the stratified epithelial layer, what can be suggested about the tissue section?" "The tissue section may represent a specialized region where the dense cellular packing overrides the need for visible connective tissue" "The epithelium is located over a well-defined basement membrane as typically observed" "The lack of visible underlying connective tissue indicates poor tissue preparation" "An underlying connective tissue layer is absent, which is characteristic for this type of epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3695.jpg" -"3696" "Based on the tissue architecture, what can be inferred about the tissues' condition?" "Tumorigenesis" "Tissue Ischemia" "Regenerative Process" "Normal Tissue Homeostasis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3696.jpg" -"3697" "Based on the structure and shape of the epithelial layer, what function can be inferred about the tissue?" "Muscular contraction" "Structural support only" "Protection and barrier formation" "High absorptive or secretory function" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3697.jpg" -"3698" "Based on the staining pattern observed in the tissue section, what is the predominant type of cytoplasmic staining visible in the central area of the altered tissue architecture?" "Abundant eosinophilic cytoplasm" "Predominantly basophilic cytoplasm" "Cytoplasm with mixed eosinophilic and basophilic staining" "Hyalinization of the cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3698.jpg" -"3699" "Which of the following best characterizes the channels seen within the epidermis?" "Filled with dense eosinophilic material and increased elastic fibers" "Containing fibroblastic proliferation" "Showing evidence of neutrophilic infiltration" "Filled with keratinaceous debris" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3699.jpg" -"3700" "Based on the characteristics of the epidermis observed in this image, which underlying condition is most consistent with these findings?" "Lichen simplex chronicus" "Pseudoxanthoma elasticum (PXE)" "Dermatofibroma" "Bullous pemphigoid" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3700.jpg" -"3701" "What is the overall cellular arrangement observed in the center of the image?" "Whorled arrangement" "Rosette-like formation" "Palisading pattern" "Diffuse and disorganized" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3701.jpg" -"3702" "Upon examining the fibrous capsule, how would you describe its appearance under hematoxylin and eosin staining in relation to its cellular density?" "Hypocellular with deep eosinophilic staining" "Hypocellular with pale eosinophilic staining" "Hypercellular with profound eosinophilic staining" "Hypercellular with pale eosinophilic staining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3702.jpg" -"3703" "What is the most probable diagnosis based on the cellular morphology seen in this image?" "Schwannoma" "Paraganglioma" "Hepatocellular carcinoma" "Adrenocortical carcinoma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3703.jpg" -"3704" "Which cells in this image are likely to demonstrate a positive immunohistochemical reaction for S100 protein?" "The larger polygonal cells with central nuclei" "The smaller, elongated cells with darker nuclei" "The cells forming glandular structures" "The cells with pyknotic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3704.jpg" -"3705" "What is the predominant inflammatory cell type observed in this image of lung tissue?" "Lymphocytes" "Neutrophils" "Basophils" "Eosinophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3705.jpg" -"3706" "What is NOT observed in the lung tissue image that could suggest a different diagnosis if present?" "Foamy macrophages" "Fibrin within the alveolar spaces" "Granulomas" "Eosinophils" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3706.jpg" -"3707" "The stromal component of this tissue section exhibits which of the following characteristics?" "Predominantly lymphocytic infiltration" "Predominantly myxoid with mucin deposition" "Highly cellular with spindle-shaped cells" "Low cellularity with adipose tissue predominance" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3707.jpg" -"3708" "What feature could be inferred from the presence of the small, round structures with dark centers within the chorionic villi?" "Degenerative changes" "Fetal capillaries" "Trophoblastic inclusions" "Syncytial knots" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3708.jpg" -"3709" "What characteristic of the prostatic glands can be observed in this microscopic view of the prostatic tissue?" "Presence of stroma with hyperplastic gland formation" "Glands with irregular size and shape but with some glandular architecture" "Completely disorganized glandular structure with no differentiation" "Uniform gland size and shape with abundant intervening stroma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3709.jpg" -"3710" "What does the cytoplasmic characteristic of the cells in this image indicate?" "Scant eosinophilic cytoplasm with high nuclear-to-cytoplasmic ratio" "Basophilic cytoplasm with indistinct cellular boundaries" "Clear cytoplasm with a low nuclear-to-cytoplasmic ratio" "Abundant eosinophilic cytoplasm with low nuclear-to-cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3710.jpg" -"3711" "Based on the observed morphology of the papillary structures in the image, what can be inferred about their complexity?" "The papillary structures display extensive secondary and tertiary branching indicative of complex architecture." "The papillary structures present with large areas of necrosis and high pleomorphism." "They exhibit smooth contours with no significant secondary branching suggestive of a benign process." "The papillae have fused together forming complex, cribiform structures." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3711.jpg" -"3712" "Assessing the staining characteristics of the cells, what can be said about the nuclei?" "The nuclei are largely pyknotic with irregular distribution." "The nuclei are predominantly vesicular with prominent nucleoli." "The nuclei are faintly stained and difficult to identify." "The nuclei are hyperchromatic and relatively uniform in size." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3712.jpg" -"3713" "What can be inferred about the connective tissue stroma separating the glands in the image?" "The stroma contains scattered fibroblasts with a sparse inflammatory infiltrate." "The stroma is densely packed with adipocytes." "The stroma is highly cellular with numerous mitotic figures." "The stroma appears acellular with abundant hyalinization." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3713.jpg" -"3714" "How would you describe the arrangement of the nuclei within the suspected nerve bundle?" "Disorganized and scattered" "Whorled pattern" "Hyperchromatic and overlapping" "Clusters of multiple nuclei within a single cell" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3714.jpg" -"3715" "What is the appearance of the stratum corneum in this H&E stained section?" "Preserved without disruption" "Completely absent" "Thinning and focal disruption" "Thickened with parakeratosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3715.jpg" -"3716" "What arrangement pattern do the small round cells exhibit in the microscopic image?" "Rosette formation" "Organized into nests or cords" "Single-file pattern" "Disarrayed with no specific pattern" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3716.jpg" -"3717" "What is the appearance of the stroma in the tissue sample shown in the image?" "Myxoid with abundant ground substance" "Hyalinized and glassy" "Dense irregular connective tissue" "Loose connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3717.jpg" -"3718" "Considering the vascular feature in this microscopic image, which element can be clearly identified within the tissue?" "Lymphatic vessel with a thin wall" "Blood vessel surrounded by hyalinized stroma" "Sinusoid with discontinuous endothelium" "Large artery with muscular wall" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3718.jpg" -"3719" "What histological feature is notably absent from the image of this myxoid neoplasm?" "Increased mitotic activity" "Abundant collagenous stroma" "Prominent vascular structures" "Dyscohesive tumor cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3719.jpg" -"3720" "Based on the histological image, what is the predominant cell type found in the layers below the superficial keratinized cells?" "Columnar cells with apical microvilli" "Basophilic cells with central, rounded nuclei" "Spindle-shaped cells with scant cytoplasm" "Squamous cells with dense eosinophilic cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3720.jpg" -"3721" "In the context of the pathological features observed, absence of which condition can be inferred in the vascular components within the visible vessels?" "Vasculitis" "Thrombosis" "Atherosclerosis" "Arteriosclerosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3721.jpg" -"3722" "Based on the histological features of the blood vessels within this section of skin, what change is evident in the vessel wall?" "Evidence of significant atherosclerosis" "No significant change, the vessel wall appears normal" "Homogeneous eosinophilic deposition suggesting amyloidosis" "Thickening of the vessel wall consistent with arteriosclerosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3722.jpg" -"3723" "Considering the size of the blood vessels shown in the image, which term best describes their abnormal size relative to typical dermal blood vessels?" "Aneurysmal dilation" "Arteriovenous malformation" "Telangiectasia" "Varicosities" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3723.jpg" -"3724" "In the deeper layers of the epithelium, what type of appearance do the cells exhibit?" "Basal layer uniformity" "Neutrophilic margination" "Cellular pleomorphism" "Uniform hyperchromatic nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3724.jpg" -"3725" "What histological feature is observed in the flaky, white superficial material present at the top of the section?" "Parakeratosis" "Orthokeratosis" "Hyperkeratosis" "Neutrophilic infiltration" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3725.jpg" -"3726" "What is the appearance of the cytoplasm in the spindle cells shown in the image?" "Abundant basophilic cytoplasm" "Vacuolated cytoplasm" "Moderate eosinophilic cytoplasm" "Sparse eosinophilic cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3726.jpg" -"3727" "What cellular feature is indicated by the presence of centrally located nuclei within the muscle fibers?" "Fibroblasts" "Cardiomyocytes" "Skeletal muscle cells" "Smooth muscle cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3727.jpg" -"3728" "What morphological characteristic of the nuclei can be observed in the glomerulus on the right side that indicates an active inflammatory process?" "Enlarged mononuclear cells" "Single, round nuclei of monocytes" "Polylobulated nuclei of neutrophils" "Decreased presence of neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3728.jpg" -"3729" "Based on the presence of small cells with dark nuclei scattered throughout the tissue, what is the most likely associated response?" "Inflammatory response" "Regenerative activity" "Benign neoplastic proliferation" "Muscle hypertrophy" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3729.jpg" -"3730" "In the microscopic image provided, how would you describe the appearance of the cytoplasm in most of the observed cells?" "Multiple vacuoles within the cytoplasm" "Homogeneous staining throughout the cytoplasm" "A clear perinuclear zone with surrounding darker eosinophilic cytoplasm" "Extensive cytoplasmic granulation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3730.jpg" -"3731" "Within the connective tissue stroma, what is the close proximity of the parafollicular cells to?" "Nerve fibers" "Thyroid follicles" "Vascular structures" "Collagen fibers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3731.jpg" -"3732" "What is the predominant architectural pattern observed in these cells?" "Solid nests" "Gland-like structures" "Papillary formations" "Nested trabeculae" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3732.jpg" -"3733" "On assessment of the nuclear features of the cells, which of the following is most consistent with the observed morphology?" "Monomorphic nuclei with evenly dispersed chromatin" "Hyperchromatic nuclei with prominent nucleoli" "Vesicular nuclei with small inconspicuous nucleoli" "Smudged chromatin without discernible nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3733.jpg" -"3734" "Which of the following erythrocyte morphologies can be observed in the blood smear?" "Acanthocytes" "Schistocytes" "Elliptocytes" "Spherocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3734.jpg" -"3735" "What observation can be made about the red cell distribution in the given image?" "Poikilocytosis" "Agglutination" "Rouleaux formation" "Anisocytosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3735.jpg" -"3736" "What characteristic feature is indicated by the presence of irregular and hyperchromatic nuclei within the cells in the provided tissue section?" "Reactive gliosis" "Neoplastic process" "Active inflammation" "High-grade neoplasia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3736.jpg" -"3737" "In the skin section displayed, which layer is directly beneath the stratum corneum and is characterized by flattened non-nucleated cells?" "Stratum spinosum" "Stratum lucidum" "Stratum granulosum" "Basal layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3737.jpg" -"3738" "What does the dermal component of the histopathological image suggest?" "Mixed dense inflammatory infiltrate with embedded fibroblasts and stromal elements" "Hypocellular dermis with abundant adipose tissue and minimal fibroblasts" "Lack of inflammatory infiltrate and presence of clear adnexal structures" "Presence of a dense, organized collagen bundle arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3738.jpg" -"3739" "In the microscopic view of the skin, what is the most notable characteristic of the nuclei in the epidermis?" "Hypochromatic nuclei with prominent nucleoli" "Uniform nuclei with dense chromatin distribution" "Small, hyperchromatic nuclei without visible nucleoli" "Hyperchromatic nuclei with possible prominent nucleoli" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3739.jpg" -"3740" "How would you describe the appearance of the cytoplasm of the atypical cells present in the epidermis?" "Sparse cytoplasm with eosinophilic staining" "Abundant eosinophilic cytoplasm without perinuclear clearing" "Scanty basophilic cytoplasm with numerous vacuoles" "Abundant pale cytoplasm with a clear perinuclear halo" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3740.jpg" -"3741" "Is there evidence of the abnormal cells invading into the deeper tissue layer beneath the epidermis?" "Yes, the abnormal cells form well-defined nests in the dermis, indicating invasion" "No, the deeper layer shows inflammatory infiltrate suggesting superficial involvement" "Yes, there's a clear invasion of abnormal cells into the underlying connective tissue" "No, the underlying dermis shows normal connective tissue without sign of invasion" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3741.jpg" -"3742" "Considering the organization of the tissue architecture in this image, which of the following statements is accurate?" "Squamous differentiation is evident" "Tissue architecture is organized into well-defined layers" "Disorganized tissue architecture with no evidence of squamous differentiation" "Presence of glandular structures indicating colonic tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3742.jpg" -"3743" "How would you describe the cellularity of the observed tissue?" "Hypercellular with numerous mitoses" "Relatively acellular with sparse cellular elements" "Organized in clusters with signet-ring cells" "Moderately cellular with mixed cell populations" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3743.jpg" -"3744" "Considering the lack of a certain feature, what can be inferred about the tissue in this image?" "Vascular invasion is prominently absent" "There is a distinct absence of necrosis" "No significant inflammation is observed" "There is an absence of cellular atypia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3744.jpg" -"3745" "What type of staining pattern is evident in the non-calcified cartilaginous areas?" "Uniform eosinophilic staining" "Predominantly basophilic with patches of eosinophilia" "Necrosis" "Hyalinization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3745.jpg" -"3746" "The regularity and appearance of the ductal structures predominantly suggest what kind of process?" "Neoplastic transformation" "Normal architecture" "Dysplastic growth" "Inflammatory response" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3746.jpg" -"3747" "Based on the eosinophilic staining of this tissue section, what component is most abundant in the densely stained areas?" "Reticular fibers" "Ground substance" "Elastic fibers" "Collagen fibers" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3747.jpg" -"3748" "What is the most observable characteristic of the nuclei in the densely packed cell regions of this tissue sample?" "Monomorphism and uniform staining" "Multinucleation with small nuclei" "Hyperchromasia indicative of high DNA content" "Uniformity in size suggestive of low mitotic activity" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3748.jpg" -"3749" "What morphological feature of the glomeruli suggests a pathological alteration?" "Presence of open capillary loops" "Uniform podocyte foot process effacement" "Expansion of Bowman's space" "Shrunken appearance of glomeruli" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3749.jpg" -"3750" "Based on the tissue morphology, what type of tissue change can be observed in the image?" "Hyperplasia" "Metaplasia" "Necrosis" "Dysplasia" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3750.jpg" -"3751" "Based on the appearance of the tissue matrix surrounding the cells, which description is most accurate?" "Dense and fibrous" "Delicate and fibrous" "Amorphous and acellular" "Hyalinized and avascular" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3751.jpg" -"3752" "Based on the arrangement of cells in this image, what pattern can be observed?" "Rosette formation" "Pseudo-rosette formation" "Fascicular pattern" "Alveolar pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3752.jpg" -"3753" "Which type of cells can be identified by their bilobed nuclei and granular cytoplasm in the mucous plug?" "Basophils" "Eosinophils" "Lymphocytes" "Neutrophils" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3753.jpg" -"3754" "What type of epithelial cells can be observed lining the passageway in the respiratory tissue?" "Columnar epithelial cells" "Transitional epithelial cells" "Squamous epithelial cells" "Cuboidal epithelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3754.jpg" -"3755" "What does the presence of a dense, eosinophilic material within the lung tissue suggest?" "Fibrin deposition" "Hyaline cartilage growth" "Mucous plug formation" "Calcified nodules" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3755.jpg" -"3756" "Based on the stratification of epithelial cells, which organ type does this histological image most likely represent?" "Small intestine" "Stomach" "Urinary bladder" "Skin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3756.jpg" -"3757" "Observing the cells closest to the lumen, what conclusion can be drawn about their shape compared to those near the basement membrane?" "The cells near the lumen are cuboidal and those near the basement membrane are squamous." "The cells near the lumen and those near the basement membrane are both squamous." "The cells near the lumen are larger and more rounded, while those near the basement membrane are smaller and more densely packed." "The cells near the lumen are more flattened and those near the basement membrane are columnar." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3757.jpg" -"3758" "Based on the microscopic features, what could be a possible diagnosis for this tissue sample?" "Pleomorphic adenoma with a chondroid element" "Fibroadenoma with dense stromal fibrosis" "Angiosarcoma with abundant neoplastic endothelial cells" "Simple cyst with a thin epithelial lining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3758.jpg" -"3759" "What cellular feature confirms the identification of the canal-like structures as blood vessels?" "Abnormal mitotic figures in the cells surrounding the lumens" "Multi-layered endothelium within the lumens" "Presence of red blood cells within the lumens" "Presence of epithelial cells lining the lumens" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3759.jpg" -"3760" "What type of growth pattern does the stroma of the tissue exhibit?" "Highly atypical with numerous mitotic figures" "Random and disorganized" "Whorled configuration" "Haphazard with high pleomorphism" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3760.jpg" -"3761" "What is the predominant cellular morphology of the densely packed cells on the left side of the tissue?" "Ciliated columnar epithelial cells" "Squamous epithelial cells" "Spindle-shaped smooth muscle cells" "Cuboidal epithelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3761.jpg" -"3762" "What feature distinguishes the right-side tissue from the left-side tissue in the image?" "Presence of interlacing bundles of cells" "Presence of ciliated columnar epithelial cells" "Presence of white spaces indicative of glands" "Presence of elongated nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3762.jpg" -"3763" "In the analysis of the surrounding stroma, what feature is notably absent?" "Evidence of a mild stromal reaction" "Presence of desmoplasia" "Signs of infiltrative growth into adjacent fatty tissue" "Necrosis within the stroma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3763.jpg" -"3764" "Identify the extracellular component interspersed between the cells in this tissue section." "Elastic fibers stained dark purple or black." "Reticular fibers forming a delicate network." "Collagen fibers appearing as pink strands." "Adipose tissue shown as clear empty spaces." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3764.jpg" -"3765" "What can be inferred about the distribution of the collagenous stroma within the lesion?" "The collagen is evenly distributed throughout the tissue" "The collagen is mostly concentrated in the central regions of the lesion" "The collagenous stroma appears to be more condensed along the periphery of the lesion" "The collagen appears less dense at the periphery, suggesting a 'trickling out' effect from the lesion" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3765.jpg" -"3766" "Based on the histological features observed in the image, what tissue structure predominates the microscopic field?" "Dense collagen bundles" "Striated muscle fibers" "Nevus cells in a nest formation" "Mature adipocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3766.jpg" -"3767" "Considering the morphological features, what pathological condition does this tissue most likely indicate?" "Hypertrophy" "Atrophy" "Inflammation" "Necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3767.jpg" -"3768" "Based on the density of the cell population and the morphology of the nuclei, what is the likely nature of the denser cellular areas?" "Mature adipose tissue" "Hyaline cartilage" "Malignant neoplastic tissue" "Connective or supportive tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3768.jpg" -"3769" "Based on close examination of the histological features observed around the hair follicles, what is the most likely composition of the cellular infiltrate?" "Lymphocytic infiltrate with occasional plasma cells" "Granulomatous inflammation with multinucleated giant cells" "Lymphocytic infiltrate with eosinophils" "Predominantly neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3769.jpg" -"3770" "Based on the histology presented, which cellular feature is most consistent with the rounded and oval spaces found in the image below the dense cortical bone layer?" "Chondrocytes within lacunae" "Fibroblasts within connective tissue" "Adipocytes typical of bone marrow" "Basophilic erythroblast cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3770.jpg" -"3771" "What does the top portion of the image predominantly consist of?" "Dense fibrous connective tissue" "Adipose tissue with prominent adipocytes" "Dense cortical bone with Haversian canals" "Hyaline cartilage with chondrocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3771.jpg" -"3772" "What type of epithelial cells line the surface of the tissue depicted in the image?" "Pseudostratified epithelial cells" "Transitional epithelial cells" "Columnar epithelial cells" "Squamous epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3772.jpg" -"3773" "Based on the morphology of the cells within the glands in the stroma, what is the likely function of these cells?" "Keratinization" "Hormone production" "Mucous production" "Protein absorption" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3773.jpg" -"3774" "Based on the histological features, assess the stromal composition visible in the image." "Equal mix of collagenous and myxoid areas" "Predominantly adipose tissue" "Predominantly myxoid" "Predominantly collagenous" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3774.jpg" -"3775" "What does the organization and distribution of melanocytes in the dermis suggest?" "Actinic keratosis with superficial cell dysplasia" "Benign nevus with uniform cell growth" "Normal distribution of melanocytes without atypia" "Dysplastic nevus with moderate to severe atypia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3775.jpg" -"3776" "What kind of epithelium is predominantly lining the papillary structures observed in the image?" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "Simple cuboidal or columnar epithelium" "Simple squamous epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3776.jpg" -"3777" "Which of the following best describes the overall structural organization of the epithelial cells in this tissue section?" "Squamous with flattened cells" "Loose and disorganized with indistinct cell boundaries" "Stratified with multiple layers of cells" "Highly structured with well-defined borders" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3777.jpg" -"3778" "Based on the cellular arrangement and morphology observed, what type of tissue is primarily represented in this image?" "Glandular epithelium" "Stratified squamous epithelium" "Connective tissue" "Muscle tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3778.jpg" -"3779" "Within this stratified squamous epithelium, what does the presence of small clusters of cells with a different staining pattern suggest?" "Early signs of an inflammatory response" "Regions where there is an accumulation of melanin" "Presence of skin appendages or other structures" "Areas undergoing neoplastic transformation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3779.jpg" -"3780" "What is the predominant shape of the cells observed in the tissue sample?" "Spindle-shaped" "Round to oval" "Cuboidal" "Polygonal" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3780.jpg" -"3781" "What cellular feature is not easily distinguishable in this microscopic view of the tissue?" "Cytoplasmic boundaries of the cells" "Homogenous extracellular matrix" "Nuclear atypia such as pleomorphism" "Nuclear hyperchromasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3781.jpg" -"3782" "Which of the following cell types can be identified by their eosinophilic cytoplasm and round to oval basally located nuclei in the glandular structures highlighted in the section?" "Chief cells" "Mucous neck cells" "Parietal cells" "Enteroendocrine cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3782.jpg" -"3783" "What is the most likely level of keratinization observed in the spinous layer of the epithelium?" "No evidence of keratinization" "Mild keratinization" "Moderate keratinization" "Complete keratinization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3783.jpg" -"3784" "Judging by the arrangement of the cells and cytoplasm in the image, which of the following neoplasms does the morphology suggest?" "Melanoma" "Adenocarcinoma" "Osteosarcoma" "Schwannoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3784.jpg" -"3785" "Identify the cellular structure indicated by a star-shaped inclusion within one of the giant cells in the image." "Asteroid body" "Michaelis-Gutmann body" "Langhans giant cell" "Schaumann body" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3785.jpg" -"3786" "What is the key histopathological feature observed in the superficial dermis of this skin biopsy?" "Granulomatous inflammation" "Dense infiltrate of eosinophils" "Hair follicle involvement" "Neutrophilic infiltrate" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3786.jpg" -"3787" "Considering the cell morphology and arrangement, what does the epidermis of this biopsy predominantly display?" "Basal cell hyperplasia" "Spongiosis" "Hypergranulosis" "Eosinophilic cytoplasm in the cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3787.jpg" -"3788" "Based on the image, which cellular structures are likely stained pink and appear as triangular or line-like formations projecting from the nerve tissue?" "Axonal initial segments" "Supportive connective tissue elements" "Neuronal cell bodies" "Nodes of Ranvier" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3788.jpg" -"3789" "In this image of nerve tissue, the nuclei visible are probably those of which type of cells?" "Schwann cells and fibroblasts" "Oligodendrocytes" "Microglia" "Astrocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3789.jpg" -"3790" "Based on the tissue morphology seen in the image, which layer of the epidermis appears to be significantly thickened?" "Stratum granulosum" "Stratum spinosum" "Stratum corneum" "Stratum basale" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3790.jpg" -"3791" "In the dermis layer, what is the observed abnormality in the connective tissue?" "Edema" "Hyalinization" "Fibrosis" "Calcification" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3791.jpg" -"3792" "What feature of the thyroid follicle indicates that the tissue is likely to be from an inactive or resting thyroid gland?" "The follicular cells exhibit polymorphic nuclei" "The follicle is lined by multiple layers of cuboidal epithelial cells" "The follicle contains dense and dark-staining colloid" "The colloid appears granular and scant" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3792.jpg" -"3793" "Based on the cellular arrangement seen in the image, what is the most likely function of the cells marked by the arrow?" "They are involved in the production of thyroid hormones" "They contribute to the production of adrenal hormones" "They function in calcium homeostasis" "They serve as a structural support within the thyroid gland" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3793.jpg" -"3794" "What is the general morphology of the most prominent cells in this tissue section?" "Large with multiple nuclei, indicating a giant cell morphology" "Spindle-shaped with elongated nuclei" "Large, round and uniform, possibly yeast cells" "Small, round with dense chromatin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3794.jpg" -"3795" "What histological feature is observed in the stratum corneum of the stratified squamous epithelium shown in the image?" "Hyperkeratosis" "Dyskeratosis" "Parakeratosis" "Orthokeratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3795.jpg" -"3796" "Based on nuclear characteristics observed in this microscopic image, what feature is notably present in the neoplastic cells?" "Macronucleoli" "Multinucleation" "Hyperchromasia" "Vesicular chromatin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3796.jpg" -"3797" "What is the predominant feature in the connective tissue surrounding the adipocytes in this image?" "Abundance of leukocytes" "Large, multinucleated cells" "Dense collagen bundles" "Network of spindle-shaped cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3797.jpg" -"3798" "What does the pink, amorphous material seen in this image suggest the presence of?" "Collagen deposition" "Fibrin deposits" "Myxoid stromal changes" "Edema fluid" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3798.jpg" -"3799" "Which of the following best characterizes the inflammatory infiltrate found within the dermis?" "Presence of Melan-A positive cells consistent with melanocytic proliferation" "Diffuse infiltrate of eosinophils commonly associated with parasitic infections" "Collections of neutrophils consistent with pustule formation" "Lymphocytic infiltrate arranged in a band-like pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3799.jpg" -"3800" "Which of the following best describes the airspaces observed in this tissue sample?" "Alveolar spaces appear dilated or distorted" "Alveolar spaces show no sign of structural changes and retain normal morphology" "Alveolar spaces are small and round with significant cellular infiltration" "Alveolar spaces appear uniformly dense with thick walls" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3800.jpg" -"3801" "Based on the architecture of the tissue observed in this image, what can be inferred about its structural organization?" "No organized architecture is evident, hinting at malignancy" "The cellular arrangement indicates a reactive process" "There is a discernible pattern suggestive of benign morphology" "The tissue exhibits well-differentiated structures" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3801.jpg" -"3802" "What is the predominant pattern of lung injury observed in this microscopic image?" "Organizing pneumonia pattern" "Usual interstitial pneumonia pattern" "Non-specific interstitial pneumonia pattern" "Lymphoid interstitial pneumonia pattern" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3802.jpg" -"3803" "Based on the organization and morphology of the predominant cells in this tissue section, what type of muscle tissue are we observing?" "Smooth muscle with elongated cells" "Striated muscle with branching fibers" "Cardiac muscle with central nuclei" "Striated muscle with intercalated discs" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3803.jpg" -"3804" "Regarding the stroma that surrounds the duct-like structures, which of the following best describes its morphology?" "Hyalinized collagenous matrix" "Dense connective tissue matrix" "Adipose tissue" "Loose, myxoid connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3804.jpg" -"3805" "Based on the tissue morphology, which specific cellular characteristic is evident in the densely populated purple-stained areas?" "Spindle-shaped cells" "Columnar epithelial cells" "Squamous epithelial cells" "Signet-ring cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3805.jpg" -"3806" "What cytoplasmic characteristic is evident in the cells of this tissue section?" "Very scant, almost transparent cytoplasm" "Highly basophilic cytoplasm without any variation" "Presence of multiple bold granules throughout the cytoplasm" "Abundant eosinophilic cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3806.jpg" -"3807" "Based on the radial structure and cellular distribution, which zone is represented by the densely packed lymphocytes that stain darker at the periphery of the follicles?" "Paracortical zone" "Thymic-dependent zone" "Mantle zone" "Marginal zone" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3807.jpg" -"3808" "In which quadrant is the lamellar fibrosis most prominently organized into parallel bands separating clusters of cells?" "Top Left Quadrant" "Top Right Quadrant" "Bottom Right Quadrant" "Bottom Left Quadrant" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3808.jpg" -"3809" "Which quadrant shows trabecular arrangement of tumor cells separated by fibrous stroma?" "Bottom Right Quadrant" "Bottom Left Quadrant" "Top Left Quadrant" "Top Right Quadrant" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3809.jpg" -"3810" "In which quadrant do the tumor cells exhibit more homogeneous eosinophilic cytoplasm and pseudoglandular pattern?" "Bottom Left Quadrant" "Bottom Right Quadrant" "Top Left Quadrant" "Top Right Quadrant" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3810.jpg" -"3811" "Considering the appearance of the nuclei, how would you characterize them?" "Monomorphic and hyperchromatic" "Monomorphic and hypochromatic" "Pleomorphic and hyperchromatic" "Pleomorphic and hypochromatic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3811.jpg" -"3812" "What does the arrangement and overall morphology of the cells suggest about the lesion?" "Presence of severe cytological atypia" "Evidence of squamous differentiation" "High likelihood of malignancy" "Indicative of a benign melanocytic lesion" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3812.jpg" -"3813" "What is the predominant staining characteristic of the cartilaginous matrix seen in the provided microscopic image?" "Pale eosinophilic with variable cell morphology" "Homogeneously basophilic with uniform cell distribution" "Deeply basophilic with tightly packed cells" "Strongly eosinophilic with spindle-shaped cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3813.jpg" -"3814" "What is the predominant characteristic of the cells present in the tissue matrix?" "Large with abundant cytoplasm containing dark pigment" "Uniformly shaped with small, regular nuclei" "Small and organized in well-defined clusters" "Small with scant cytoplasm and no visible pigment" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3814.jpg" -"3815" "Considering the structural organization of the tissue, what is primarily observed?" "Fibrous tissue with abundant extracellular matrix and few cells" "A well-preserved tissue architecture with minimal disruption" "Predominantly organized glandular structures" "Hypercellular areas with loss of normal tissue architecture" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3815.jpg" -"3816" "What is the predominant cell morphology observed in the image provided?" "Spindle cells with elongated nuclei" "Round cells with abundant cytoplasm" "Cuboidal cells with central nuclei" "Multinucleated giant cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3816.jpg" -"3817" "How would you describe the stroma that is present in the image?" "Dense sclerotic stroma with minimal cellularity" "Highly cellular stroma with minimal intervening collagen" "Adipose-rich stroma with fat droplets" "Abundant myxoid stroma with uniform distribution" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3817.jpg" -"3818" "What is the nature of the palisading pattern seen in this image?" "Peripheral with uniform palisading nuclei in basal cell carcinomas" "Peripheral with irregular palisading nuclei in melanomas" "Central with pleomorphic palisading nuclei in squamous cell carcinomas" "Central with orderly palisading nuclei in neurofibromas" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3818.jpg" -"3819" "The cells in the image display significant cytoplasmic clearing. What is one potential cause for this appearance in a neoplastic process?" "Cytoplasmic protein accumulation" "Epstein-Barr virus infection" "Cytoplasmic lipid accumulation" "Cytoplasmic glycogen accumulation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3819.jpg" -"3820" "In evaluating the morphology of the epidermis, which layer remains unaffected by the elastotic changes?" "Stratum lucidum" "Stratum granulosum" "Stratum corneum" "Stratum basale" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3820.jpg" -"3821" "Based on the morphology of the glands, what pattern do they most closely represent?" "Tubular with a somewhat regular architectural pattern" "Solid nests without any identifiable lumen" "Highly disorganized with frequent cellular overlap" "Irregular, branching and complex" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3821.jpg" -"3822" "What morphology is displayed by the epithelial cells lining the glands in this section of colonic mucosa?" "Cuboidal with centralized nuclei" "Squamous with hyperkeratosis" "Elongated with pseudostratified nuclei" "Columnar with basal nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3822.jpg" -"3823" "How would you describe the architectural pattern of the glandular structures visible in the tissue sample?" "Uniform and rounded with centralized lumens" "Tubular with smooth contours and regular spacing" "Serrated with saw-tooth patterns at the luminal surface" "Villous with finger-like projections into the lumen" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3823.jpg" -"3824" "Given the organization of the cells, how would you characterize their arrangement?" "Forming papillary structures with central fibrovascular cores" "Arranged in a palisading pattern along the basement membrane" "Arranged in undefined, irregular clusters without a regular pattern" "Organized in well-defined, uniform acini" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3824.jpg" -"3825" "Based on the examination of the tissues present, which regions in the image appear to represent sites of endochondral ossification?" "Areas with densely packed collagen fibers" "Regions with light pink homogenous appearance" "Well-defined structures with darkly stained spots within the matrix" "More densely cellular tissue with areas of extracellular matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3825.jpg" -"3826" "Identify the tissue type represented by the lighter pink homogeneous regions in the image." "Chondrocytic cartilaginous matrix" "Mature lamellar bone" "Fibrous connective tissue" "Adipose tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3826.jpg" -"3827" "What is the nuclear chromatin pattern seen in the cells within this microscopic image?" "Hyperchromatic with clearing" "Vesicular with prominent nucleoli" "Coarse and clumped" "Finely dispersed with 'salt and pepper' appearance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3827.jpg" -"3828" "The glandular structures in this image are surrounded by a network of which type of tissue?" "Elastic connective tissue" "Adipose tissue" "Dense regular connective tissue" "Fibrous connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3828.jpg" -"3829" "Based on the morphology of nuclei, what feature can be observed in the predominant cell type in the image?" "The nuclei are small and uniformly spherical" "The nuclei are central and irregularly shaped" "The nuclei are peripheral with a spindle shape" "The nuclei are singular and located at the polar ends" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3829.jpg" -"3830" "What is the predominant pattern of cell organization within the nodules displayed in the tissue section?" "Whorled and organized arrangement" "Loose and myxoid arrangement" "Whorled and palisading arrangement" "Disordered and pleomorphic arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3830.jpg" -"3831" "What does the tissue architecture reveal about the nature of the cells?" "Organized, well-differentiated cellular arrangement" "Disorganized, pleomorphic cellular pattern" "Monotonous cells with uniform size and shape" "Regular, evenly distributed cells respecting boundaries" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3831.jpg" -"3832" "Considering the overall morphology of the tissue, which characteristic is NOT evident in the provided image?" "Abundant eosinophilic extracellular matrix" "Absence of significant atypical mitotic figures" "Predominantly spindle cell morphology" "Focal areas exhibiting pleomorphism" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3832.jpg" -"3833" "What is the predominant tissue feature that characterizes the large pink area in the center of the image?" "Dense lymphocytic infiltrate" "Dense collagen bundles" "Necrotic tissue debris" "Granulation tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3833.jpg" -"3834" "Which pattern is predominantly observed in the arrangement of cells in this section of skin tissue?" "Alveolar pattern" "Palisading pattern" "Rosette pattern" "Storiform pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3834.jpg" -"3835" "Identify the structures that appear to be part of the airway in the image based on their cellular lining." "Structures delineated by ciliated pseudostratified columnar epithelium" "Structures with a thicker epithelial cell lining" "Structures lined with stratified squamous epithelial cells" "Structures featuring a simple columnar epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3835.jpg" -"3836" "Identify the potential pathological indication from the cellular arrangement in the central portion of the image." "A focus of inflammation indicated by a dense cluster of cells with dark-stained nuclei" "Formation of granulation tissue with fibroblasts proliferation" "Hyperkeratosis showing increased layers of keratinocytes" "Neoplastic transformation with atypical nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3836.jpg" -"3837" "How is the cytoplasmic quantity of the spindle cells in this image best described?" "Abundant, with distinct cell borders" "Vacuolated with irregular cell margins" "Minimal with spindled cell processes" "Moderate with clear perinuclear halos" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3837.jpg" -"3838" "Evaluate the architecture of the tissue. Which description best fits the observed pattern?" "Dispersed with a microcystic pattern" "Organized in well-defined nests" "Dense with a storiform pattern" "Vague, interwoven fascicular structure" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3838.jpg" -"3839" "What pattern of neoplastic epithelial cell spread is exhibited in the ductal structures within this microscopic image?" "Exophytic growth" "Intraductal spread" "Pagetoid spread" "Lymphovascular invasion" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3839.jpg" -"3840" "Assessing the stroma in the colonic tissue shown in the image, what is its appearance?" "Fibrotic with extensive collagen deposition" "Sclerotic and hyalinized" "Necrotic with loss of cellular detail" "Edematous and vascularized" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3840.jpg" -"3841" "Assessing the morphology and distribution of cells near the bone surfaces, which type of cells predominates in this image?" "Fibroblasts aligned in rows" "Osteoblasts with cuboidal shape" "Osteoclasts in resorption lacunae" "Adipocytes with large vacuoles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3841.jpg" -"3842" "What type of extracellular matrix predominates in the image?" "Hyaline cartilage" "Dense, irregular connective tissue" "Myxoid stroma" "Elastic cartilage" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3842.jpg" -"3843" "What type of epithelium is observed on the right side of the image?" "Simple squamous epithelium" "Simple columnar epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3843.jpg" -"3844" "What type of inflammatory cells predominate in the aggregates within the invasive area?" "Eosinophils" "Basophils" "Lymphocytes" "Neutrophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3844.jpg" -"3845" "Based on the staining characteristics and tissue architecture, what is the most likely process occurring in the tissue sample?" "Hyperplasia" "Metaplasia" "Anaplasia" "Necrosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3845.jpg" -"3846" "What is the predominant type of cell forming the dense cluster at the center of the image?" "Neutrophils" "Adipocytes" "Macrophages" "Fibroblasts" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3846.jpg" -"3847" "What observation best matches the appearance of the dermal collagen in the stained skin tissue section?" "Homogeneous eosinophilic texture" "Paler, homogenized areas indicating collagen degeneration" "Granular basophilic deposits typical of calcinosis cutis" "Thick, hyalinized bundles typical of keloid formation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3847.jpg" -"3848" "Considering the presence of pink-staining fibers within the extracellular matrix, what type of deposit is likely indicated?" "Glycogen deposits" "Hemosiderin deposits" "Amyloid deposits" "Collagen bundles" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3848.jpg" -"3849" "Based on the organization of the spindle-shaped cells within this tissue section, what can be inferred about the growth pattern?" "The cells are arranged in a circular, whorled pattern." "The cells are distributed in a disorganized manner, oriented in various directions." "The cells exhibit a highly organized, parallel arrangement." "The cells form glandular structures with a clear lumen." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3849.jpg" -"3850" "In the given field of view, which feature is not observed within the stroma of the tissue?" "Dilated vascular channels" "Variable fibrosis" "Significant stromal invasion" "Preserved lobular structures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3850.jpg" -"3851" "Based on the observed histological features, which cell type predominates in the tissue section?" "Osteocytes" "Hepatocytes" "Schwann cells" "Fibroblasts" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3851.jpg" -"3852" "When analyzing the cellular morphology within this tissue section, which characteristic is NOT consistent with the features of a capillary hemangioma?" "Small, rounded open spaces likely representing vascular lumina" "Areas of densely packed cells with a somewhat round morphology" "Spindle-shaped cells arranged in a whorled pattern" "Presence of blood vessels with organized cellular layers in their walls" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3852.jpg" -"3853" "What type of cellular arrangement within this tissue sample helps differentiate a capillary hemangioma from other types of vascular lesions?" "Necrotic areas intersplaced with viable tumor cells" "Disorganized clusters of cells with hyperchromatic nuclei" "Aggregates of cells with round to oval nuclei and visible nucleoli" "Uniformly distributed cells with high nuclear-to-cytoplasmic ratio" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3853.jpg" -"3854" "What feature of the surrounding lung parenchyma can be observed in the image?" "Extensive hemorrhage and hemosiderin-laden macrophages" "Presence of numerous large air-filled cavities" "Dense fibrosis with loss of alveolar architecture" "More loosely arranged cells with abundant clear spaces" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3854.jpg" -"3855" "What is the predominant cellular morphology of the secretory cells within the acini outlined in green?" "Spindle-shaped with elongated nuclei" "Squamous with central round nuclei" "Columnar with apically located nuclei" "Pyramidal with basally located nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3855.jpg" -"3856" "What do the lighter staining and often more spacious lumen identify adjacent to the acini that are not outlined?" "Islets of Langerhans" "Acinar cells" "Interstitial tissue" "Ducts" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3856.jpg" -"3857" "The architecture of the cells surrounding the cystic space is most consistent with what type of tissue?" "Neoplastic tissue with high-grade features" "Dysplastic squamous epithelium" "Normal organ tissue architecture" "Hyperplastic glandular tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3857.jpg" -"3858" "What is the predominant cell type lining the cystic space in the image?" "Squamous epithelial cells" "Histiocytes with foamy cytoplasm" "Lymphocytes" "Glandular epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3858.jpg" -"3859" "Based on the histological features observed, what is the appearance of the nuclei in the serous gland cells?" "The nuclei have a low nuclear to cytoplasmic ratio" "The nuclei are pale and not visible" "The nuclei are small and inconspicuous" "The nuclei are large and likely more basophilic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3859.jpg" -"3860" "What cellular characteristics are observable in the cyst-like spaces?" "Ependymal cells" "Myxoid (mucoid) material" "Keratinizing squamous epithelium" "Necrotic debris" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3860.jpg" -"3861" "Based on the observed nuclear-to-cytoplasmic ratio in the image, which statement is the most accurate?" "The cells exhibit a low nuclear-to-cytoplasmic ratio" "The cytoplasm is abundant, overshadowing the nuclei" "The nuclear-to-cytoplasmic ratio is high" "The nuclear-to-cytoplasmic ratio is consistent with benign etiology" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3861.jpg" -"3862" "What cellular morphology is prominently displayed by the cells in the tissue section shown?" "Cuboidal cells with 'hobnailing' into air spaces" "Squamous cell morphology with keratin pearls" "Columnar epithelial cells with brush border specialization" "Spindle-shaped cells with elongated nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3862.jpg" -"3863" "What does the extracellular matrix surrounding the cells in the image suggest?" "The formation of a hydropic or edematous extracellular space" "Evidence of fibrosis or scarring within the tissue" "The development of calcifications within the tissue" "The presence of abundant myxoid stroma" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3863.jpg" -"3864" "What can be inferred about the arrangement of the cells in this tissue sample?" "Well-organized structure reminiscent of normal tissue architecture" "Homogeneous cell density throughout the tissue" "Haphazard arrangement with varying cell density" "Uniform cell size with regular spacing" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3864.jpg" -"3865" "What tissue organization is indicated by the elongated cells with parallel nuclei on the left side of the green line?" "Simple columnar epithelium" "Stratified squamous epithelium" "Fibrous connective tissue" "Adipose tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3865.jpg" -"3866" "What do the clusters of more basophilic cells interspersed within the epithelium likely represent?" "Lymphocytic infiltration" "Areas of calcification" "Monotonous poroid population" "Keratin pearl formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3866.jpg" -"3867" "Based on the tissue architecture observed, what can you infer about the organization of the cells?" "Cells are arranged in a disorganized pattern" "Cell arrangement resembles normal tissue architecture" "There is a well-defined pattern of cell arrangement" "The cells are evenly dispersed throughout the tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3867.jpg" -"3868" "What does the cytoplasmic staining reveal about the cell composition?" "The cells contain scant, basophilic cytoplasm" "Cytoplasm appears ample and eosinophilic" "Cytoplasm displays multiple, dark-staining granules" "There is a high quantity of glycogen within cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3868.jpg" -"3869" "Based on the microscopic image, what feature is most prominent in the cells' appearance?" "High mitotic activity with visible mitotic figures" "Regular and well-defined cell boundaries" "Multinucleation of the cells" "Presence of prominent nucleoli within the nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3869.jpg" -"3870" "Based on the observed morphology, which structures within the dermal layer can be distinguished in this section?" "Blood vessels" "Sebaceous glands" "Hair follicles" "Eccrine sweat glands" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3870.jpg" -"3871" "What is the predominant staining pattern observed in the smooth muscle tissue shown in the image?" "Uniformly pink staining" "Dark purple staining throughout" "Pink staining with darker regions corresponding to nuclei" "Pink staining with sporadic green specks" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3871.jpg" -"3872" "What type of cellular structures can be observed within the stromal component surrounding the tubules?" "Adipocytes" "Fibroblasts" "Endothelial cells" "Inflammatory cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3872.jpg" -"3873" "What is the predominant feature observed in the central region of this histological lung tissue image?" "Enlargement of air spaces" "Granulomatous formations" "Dense inflammatory infiltrate" "Thickened alveolar walls" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3873.jpg" -"3874" "Based on the cytoarchitecture, what can be inferred about the predominant type of cells in these tissue fragments?" "They are primarily squamous epithelial cells with keratinization." "They exhibit features of differentiated cells with a low nucleus-to-cytoplasm ratio." "The cells appear to be dysplastic with a significant variation in nuclear size and shape." "They are predominantly undifferentiated, with a high nucleus-to-cytoplasm ratio." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3874.jpg" -"3875" "What does the structural organization of the tissue fragments suggest about the potential function of this tissue?" "The structure points towards a sensory function, like that of olfactory epithelium." "The tissue is likely involved in protective barrier functions, such as skin." "It suggests a glandular function, possibly related to fluid secretion." "The architecture indicates a role in filtration, such as kidney glomeruli." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3875.jpg" -"3876" "What does the nuclear-to-cytoplasmic ratio of the cells suggest about the potential behavior of the lesion?" "The slight increase in nuclear-to-cytoplasmic ratio could be consistent with reactive atypia" "The increased nuclear-to-cytoplasmic ratio in some cells indicates a possible malignant transformation" "The nuclear-to-cytoplasmic ratio is within normal limits, showing no signs of malignancy" "The cells appear to be highly anaplastic with a high nuclear-to-cytoplasmic ratio, suggesting aggressive behavior" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3876.jpg" -"3877" "Based on the stromal features surrounding the papillary structures, what cellular constituents are primarily observed?" "Myxoid stroma with abundant extracellular matrix" "Predominantly adipose tissue" "Homogeneous acellular collagen" "Dense fibrous connective tissue with scattered inflammatory cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3877.jpg" -"3878" "What type of epithelium is present at the bottom of this histological image?" "Simple columnar epithelium" "Pseudostratified ciliated columnar epithelium" "Transitional epithelium" "Stratified squamous epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3878.jpg" -"3879" "Based on the cellular characteristics visible in the image, what is the most likely diagnosis of this skin lesion?" "Squamous cell carcinoma" "Psoriasis" "Plantar wart" "Seborrheic keratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3879.jpg" -"3880" "Identifying the specific morphology, what feature is notably absent in this lesion?" "Munro's microabscess" "Dysplastic cells" "Parakeratosis" "Koilocytosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3880.jpg" -"3881" "Which morphological feature is most prevalent in the dense collection of cells observed in this tissue section?" "Abundant cytoplasm" "Uniform cellular size and shape" "Marked nuclear pleomorphism" "Presence of multinucleated giant cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3881.jpg" -"3882" "In this tissue section, the lighter, irregularly shaped areas most likely represent what type of structures?" "Keratin pearls" "Sinusoidal spaces" "Mucinous deposition" "Well-defined glandular lumens" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3882.jpg" -"3883" "What is the distinguishing feature of the columnar epithelial cells as seen in the image?" "They possess multiple nuclei." "They exhibit squamous cell morphology." "They have cilia on their apical surface." "They contain large lipid droplets." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3883.jpg" -"3884" "What characteristic feature is observed in the large, clear cells in the upper left corner of the image?" "Hyperchromatic nuclei" "Multiple nuclei" "Prominent nucleoli" "Small nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3884.jpg" -"3885" "In the region that appears myxoid, how are the spindle-shaped cells oriented?" "Oriented in various directions" "In a single file" "In a parallel alignment" "In a circular pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3885.jpg" -"3886" "What is the nature of the inflammatory infiltrate visible within the dermal layer beneath the acantholytic area?" "Neutrophilic infiltrate" "Granulomatous infiltrate" "Lymphocytic infiltrate" "Eosinophilic infiltrate" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3886.jpg" -"3887" "What does the cellular arrangement primarily observed at the center of the tissue section indicate?" "Extensive necrosis characterized by a large zone of cell death" "Dense areas with a proliferation of spindle-shaped cells" "Marked pleomorphism and severe cytologic atypia" "High mitotic activity with numerous mitotic figures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3887.jpg" -"3888" "Given the observed cellular and tissue morphology, which differential diagnosis could be considered for this specimen?" "Melanoma evidenced by melanin pigment" "Liposarcoma characterized by adipocyte proliferation" "Schwannoma with possible neuroblastic differentiation" "Osteosarcoma due to the presence of osteoid formation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3888.jpg" -"3889" "What is the most notable characteristic of the superficial cell layer in this tissue section?" "The presence of prominent intercellular bridges" "The presence of numerous goblet cells" "The appearance of large, hyperchromatic nuclei" "The lack of nuclei indicating keratinization" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3889.jpg" -"3890" "What cellular infiltrate can be identified within the epithelium indicative of an immune response?" "Neutrophils with multi-lobed nuclei" "Monocytes with kidney-shaped nuclei" "Eosinophils with bi-lobed nuclei" "Lymphocytes with condensed chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3890.jpg" -"3891" "What type of cellular arrangement can be observed in the epithelium?" "Pseudostratified columnar epithelium" "Stratified squamous epithelium" "Multilayered transitional epithelium" "Single-layered squamous epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3891.jpg" -"3892" "Based on the cellular organization, which feature best describes the arrangement of the epithelial cells in this image?" "Single layer with cells organized uniformly" "Single layer with a pseudostratified appearance" "Multiple layers with no regular arrangement" "Multiple layers with surface cells flattened" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3892.jpg" -"3893" "In the given microscopic image, what is the orientation of the nuclei within the follicle-like structures?" "Apically located at the top end of the cells" "Basally located near the basal lamina" "Centrally located within the cells" "Outside the cellular boundary" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3893.jpg" -"3894" "What does the overall morphology of the epithelial tissue suggest in this image?" "Squamous metaplasia with keratin layers formation" "Neoplastic changes with potential malignancy" "Normal variation with functional glandular tissue" "Inflammation with neutrophil infiltration" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3894.jpg" -"3895" "What type of epithelium is present at the top of the image?" "Pseudostratified ciliated columnar epithelium" "Transitional epithelium" "Squamous epithelium" "Simple columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3895.jpg" -"3896" "Based on the microscopic image, what kind of muscular tissue is observed at the lower part?" "Myoepithelial cells" "Striated skeletal muscle" "Cardiac muscle" "Smooth muscle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3896.jpg" -"3897" "Based on the cellular morphology, what is the predominant shape of the cells in the glandular tissue?" "Spherical" "Spindle-shaped" "Columnar" "Cuboidal" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3897.jpg" -"3898" "The regions with the denser, less defined eosinophilic substance in the image suggest which of the following processes?" "Endochondral ossification" "Direct bone formation" "Mature bone remodeling" "Osteoclast activity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3898.jpg" -"3899" "Identify the type of giant cells seen in the image characterized by large, irregularly shaped nuclei." "Touton giant cells" "Foreign body giant cells" "Langhans giant cells" "Osteoclasts" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3899.jpg" -"3900" "What characteristic best describes the stroma between the cellular nodules?" "Dense and eosinophilic" "Myxoid and loose" "Edematous with inflammatory infiltrate" "Pink and collagenous" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3900.jpg" -"3901" "Assessing the overall tissue architecture, how would you describe the growth pattern of the nodules?" "Sporadic with significant disarray" "Disorganized with infiltrative margins" "Anaplastic with tumor giant cells" "Organized with a thick eosinophilic wall encapsulating the nodules" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3901.jpg" -"3902" "Considering the organization of the tissue into lobules, what is a possible diagnosis suggested by the image?" "Oncocytoma" "Warthin tumor" "All of the above" "Mucoepidermoid carcinoma" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3902.jpg" -"3903" "What cytoplasmic characteristic can be observed in the abnormal cells?" "Absence of granules" "Presence of fine pink granules" "Homogeneous pink-staining cytoplasm" "Abundance of cytoplasm with few visible organelles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3903.jpg" -"3904" "In the provided image, what type of supporting tissue is likely found adjacent to the ependymal cells on the outside?" "Loose areolar connective tissue" "Dense irregular connective tissue" "Hyaline cartilage" "Adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3904.jpg" -"3905" "In the histological image presented, the irregular sizing and shaping of the nuclei are indicative of what kind of epithelial cell organization?" "Simple squamous epithelium" "Stratified squamous epithelium" "Transitional epithelium" "Simple cuboidal epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3905.jpg" -"3906" "What is the primary functional implication of the observed cellular arrangement in this type of epithelium?" "Rapid diffusion and filtration" "Protection from abrasion and desiccation" "Secretion and absorption" "Distension and contraction to accommodate volume changes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3906.jpg" -"3907" "In the assessment of this tissue, the variable sizes and shapes of vascular channels, some being slit-like and others cavernous, are indicative of what type of lesion?" "Kaposi sarcoma" "Hemangioma" "Lymphangioma" "Glomangioma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3907.jpg" -"3908" "What is the histological feature visible in the stratum corneum of this skin biopsy?" "Hyperkeratosis" "Parakeratosis" "Spongiosis" "Acantholysis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3908.jpg" -"3909" "How would you describe the cellular morphology of the cells in this histopathological image?" "Columnar cells with basal nuclei" "Spindle-shaped cells with elongated nuclei" "Cuboidal cells with round nuclei" "Lymphoid cells with scant cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3909.jpg" -"3910" "What observation can be made about the cells on the right side of the image?" "Cells display abundant cytoplasm and centrally located nuclei, more characteristic of normal tissue." "There is clear evidence of tumor giant cells within the observed region." "Cells exhibit an increased nuclear-to-cytoplasmic ratio with pleomorphism." "Cells show highly variable staining intensity, indicating active mitosis." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3910.jpg" -"3911" "Based on the absence of a particular tissue, what does the tubular structure in the image most likely represent?" "Blood vessel" "Trachea" "Ureter" "Esophagus" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3911.jpg" -"3912" "Based on the histological features observed in the image, which type of inflammation is primarily indicated by the presence of abundant cells with multi-lobed nuclei?" "Lymphocytic infiltration" "Acute inflammation" "Granulation tissue formation" "Chronic granulomatous inflammation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3912.jpg" -"3913" "What does the microscopic morphology of the stromal area beneath the epithelial layer most likely indicate?" "Presence of abundant adipose tissue" "Accumulation of mucous-secreting glands" "High degree of vascularization with new blood vessel formation" "Infiltration of inflammatory cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3913.jpg" -"3914" "Based on the presence of the band-like pattern of eosinophilic necrosis, what is the most likely pattern of injury observed in this tissue?" "Coagulative necrosis" "Caseous necrosis" "Liquefactive necrosis" "Ischemic infarction" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3914.jpg" -"3915" "Identify the type of necrosis likely present within the tissue sample based on the visible morphological features." "Coagulative necrosis" "Fat necrosis" "Liquefactive necrosis" "Fibrinoid necrosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3915.jpg" -"3916" "Based on the morphology, what condition could the architectural changes in this kidney tissue sample indicate?" "Diabetic glomerulosclerosis" "Minimal change disease" "Acute pyelonephritis" "Leukocytoclastic vasculitis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3916.jpg" -"3917" "Based on the visual characteristics of the cells with vacuolated cytoplasm, which of the following differential diagnoses is most consistent?" "Keratinizing squamous cell carcinoma" "Liposarcoma" "Basal cell carcinoma" "Sebaceous carcinoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3917.jpg" -"3918" "Considering the tissue organization, which of the following best describes the morphology of the lesion with respect to its interface with the surrounding stroma?" "Irregular, invading edges" "Well-defined, demarcated border" "Extremely diffuse, undefined boundary" "Poorly delineated, infiltrating borders" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3918.jpg" -"3919" "In the extracellular matrix of this tissue, what is the dominant staining characteristic?" "Lightly stained matrix suggesting reduced cytoplasmic material" "Darkly stained matrix with evidence of abundant cytoplasmic material" "Homogeneously eosinophilic matrix consistent with hyalinization" "Presence of extensive calcification within the matrix" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3919.jpg" -"3920" "What can be inferred about the cells with lightly stained cytoplasm and small, dark-stained nuclei?" "They are likely to be neurons" "They are likely to be epithelial cells" "They are likely to be stromal cells" "They are likely to be immune cells such as lymphocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3920.jpg" -"3921" "The interlobular septa appear thickened. What conditions could this morphological change suggest?" "Interstitial edema" "Bronchiectasis" "Alveolar proteinosis" "Interstitial fibrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3921.jpg" -"3922" "Based on the cytoplasmic characteristics, which white blood cells in the image represent immature forms?" "Cells with a deep blue cytoplasm containing tiny pink granules" "Cells with a red cytoplasm and large pink granules" "Cells with a pink cytoplasm and high granularity" "Cells with a pale blue cytoplasm and no visible granules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3922.jpg" -"3923" "What is the predominant pattern of the nuclei in the muscle fibers?" "Peripherally located and irregularly spaced" "Centrally located and aligned in a straight line" "Clustered in groups at the periphery of the cells" "Randomly scattered with no specific orientation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3923.jpg" -"3924" "What cytological feature is most consistent throughout this field of view?" "Regular spacing between cells" "Uniform nuclei size" "Extensive cytoplasm" "Nuclear atypia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3924.jpg" -"3925" "What is the arrangement of the endothelial cells within the clear spaces observed in the tissue?" "They are arranged in a papillary or tufted fashion" "They are arranged in a linear, orderly pattern" "They are arranged in a clustered nodular pattern" "They are arranged in a diffuse and disorganized pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3925.jpg" -"3926" "What is the predominant feature of the stroma in the provided microscopic image?" "Hyalinization" "Sclerotic stroma" "Edema" "Myxoid changes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3926.jpg" -"3927" "Identify the characteristic that is least apparent in the provided histological image." "Presence of well-formed vessels" "Myxoid background" "Hypercellularity" "Necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3927.jpg" -"3928" "In the dermis layer, which type of cell appears to dominate the inflammatory response?" "Cells with irregular, hyperchromatic nuclei" "Cells with a syncytial arrangement" "Cells with large, pale nuclei and scant cytoplasm" "Cells with bi-lobed nuclei and prominent red granules" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3928.jpg" -"3929" "Which feature is NOT associated with a benign neoplasm such as the one depicted in this image?" "Pleomorphism" "Uniform cells with a signet-ring appearance" "Cytoplasm that appears clear or white" "High mitotic activity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3929.jpg" -"3930" "What is the predominant cell shape observed in the tissue?" "Polygonal cells with clear cytoplasm" "Spindle-shaped cells with eosinophilic cytoplasm" "Cuboidal cells aligning in duct-like structures" "Round cells with high cytoplasmic volume" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3930.jpg" -"3931" "What is the nature of the nuclei of the endothelial cells lining the vascular channels?" "Large with prominent nucleoli and homogeneous chromatin" "Small and hyperchromatic with uniform size" "Hyperchromatic with variable size and shape" "Uniform with bland chromatin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3931.jpg" -"3932" "What feature of cell division is evident in some cells in this image?" "Presence of binucleated cells" "Absence of mitotic figures" "Presence of atypical mitotic figures" "Presence of typical mitotic figures" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3932.jpg" -"3933" "Based on the histological features observed in the image, which of the following best characterizes the appearance of the glands present?" "Irregularly spaced with abundant desmoplastic stroma" "Regularly spaced with minimal surrounding inflammatory infiltrate" "Varied in size with a dense surrounding stroma" "Uniformly shaped with sparse surrounding stroma" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3933.jpg" -"3934" "Considering the staining properties of the tissue shown in the image, what does the pink color predominantly represent?" "Basophilic nuclei of connective tissue" "Eosinophilic cytoplasm of epithelial cells" "Basophilic cytoplasm of muscle tissue" "Eosinophilic components of the connective tissue stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3934.jpg" -"3935" "In this image showing a section of skin with sub-epidermal vesicular disease, which of the following descriptions best matches the appearance of the collagen in the dermis?" "Collagen with signs of calcification" "Collagen displaying significant hyalinization and loss of fibers" "Collagen appears eosinophilic and normal without obvious signs of basophilia" "Collagen with extensive basophilia and disorganization" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3935.jpg" -"3936" "Based on the observed staining characteristics, what is the most likely staining technique used for this histological sample?" "Wright's stain" "Giemsa stain" "Hematoxylin and eosin stain" "Periodic acid-Schiff stain" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3936.jpg" -"3937" "What is the predominant nuclear feature observed in this field of view?" "Multinucleation within single cells" "Nuclei with multiple distinct nucleoli" "Uniform nuclei with fine chromatin" "Hyperchromatic nuclei with irregular shapes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3937.jpg" -"3938" "Based on the histological features visible in the image, which of the following best describes the condition of the epidermis?" "Significant hyperkeratosis" "Evidence of psoriasiform hyperplasia" "Signs of moderate to severe atrophy" "Presence of melanocytic nevi" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3938.jpg" -"3939" "What histological feature in the image supports the conclusion of a non-invasive growth pattern?" "Absence of nuclei at the basal layer" "Evidence of necrosis within the glandular lumina" "Cribriform pattern of the glandular architecture" "Presence of dense connective tissue in the stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3939.jpg" -"3940" "Analyzing the microscopic image, which pattern supports the diagnosis of benign hyperplasia?" "Cells exhibiting hyperchromasia" "Multilayering of the epithelial cells lining the glands" "The presence of 'Roman bridges' and nuclear streaming" "Overall disorganization in glandular architecture" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3940.jpg" -"3941" "What type of connective tissue encapsulates the nerve fascicles as seen in the image?" "Dense irregular connective tissue" "Adipose tissue" "Dense regular connective tissue" "Loose connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3941.jpg" -"3942" "In the tissue section, what is the character of the inflammatory cell response around the mucin pools?" "High concentration of neutrophils with multi-lobed nuclei" "Population of cells with dark purple nuclei and eosinophilic cytoplasm" "Presence of cells with round, light-staining nuclei and abundant cytoplasm" "Lacking of any apparent inflammatory cell presence" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3942.jpg" -"3943" "Which of the following features are observed in the cells when stained with hematoxylin and eosin (H&E) in the left image?" "Round cells with abundant eosinophilic cytoplasm" "Elongated spindle-like cells with hyperchromatic nuclei" "Small cells with high nucleus-to-cytoplasm ratio" "Squamous cells with intercellular bridges and keratinization" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3943.jpg" -"3944" "Assessing the stromal component in the image, which term best describes its quantity?" "Abundant with adipose infiltration" "Myxoid with gelatinous substance" "Dense with abundant collagen deposition" "Scant with focal areas of inflammation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3944.jpg" -"3945" "How would you describe the cellular arrangement around the sinusoidal spaces?" "Disorganized and erratic" "Radiating in a regular pattern" "Sparse and widely separated" "Clustered in irregular nodules" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3945.jpg" -"3946" "What does the epithelium lining the glandular structures consist of?" "A single layer of columnar cells" "A double layer of squamous cells" "A double layer of cuboidal cells" "A single layer of cuboidal cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3946.jpg" -"3947" "Based on the cellular morphology shown in the image, what is the predominant tissue characteristic observable?" "Considerable pleomorphism" "Uniformity of cytoplasmic staining" "Presence of extensive extracellular matrix" "Uniformity of nuclear size and shape" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3947.jpg" -"3948" "In the given image, which statement best describes the visible condition of the epidermis?" "The epidermis shows signs of atrophy with thinning layers" "There is hyperkeratosis with a thickened stratum corneum" "The epidermis consists of organized layers with a visible stratum corneum" "Disorganized epidermal layering and absence of the stratum corneum are apparent" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3948.jpg" -"3949" "Based on the nuclear features, the degree of cellular atypia could be described as:" "Significant with marked nuclear pleomorphism" "Moderate with some multinucleated giant cells" "Minimal with rare mitotic figures" "High with numerous abnormal mitoses" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3949.jpg" -"3950" "What cellular composition is evident surrounding the smooth muscle fibers?" "Uniform and structured rows of squamous epithelial cells" "Dense aggregates of fatty adipose tissue" "Neatly arranged rows of spindle-shaped fibroblasts" "Disorganized clusters of glandular cells with varying sizes and shapes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3950.jpg" -"3951" "What is the most likely nature of the clear spaces observed amidst the cellular infiltrate in the image?" "Mucin deposits" "Fibrotic stromal tissue" "Adipose tissue" "Areas of necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3951.jpg" -"3952" "Considering the tissue architecture and the pattern of cellular infiltration, which of the following pathologic processes does the image most likely represent?" "Acute inflammatory reaction" "High-grade malignant infiltration" "Chronic infiltrative disease" "Benign neoplastic proliferation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3952.jpg" -"3953" "Which type of cells are prominent within the matrix observed?" "Lymphocytes" "Fibroblasts" "Ganglion-like cells" "Erythrocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3953.jpg" -"3954" "What is the predominant cell type found in the mucosal layer of this tissue section?" "Transitional epithelial cells" "Pseudostratified ciliated columnar epithelial cells" "Simple columnar epithelial cells" "Stratified squamous epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3954.jpg" -"3955" "What is the predominant tissue type observed in the lower two-thirds of the image?" "Hyaline cartilage" "Dense fibrous connective tissue" "Skeletal muscle tissue" "Adipose tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3955.jpg" -"3956" "When examining the cytoplasmic characteristics of the cells in this image, which description best fits the findings?" "Abundant, clear cytoplasm" "Foamy cytoplasm" "Basophilic, granular cytoplasm" "Eosinophilic, scant cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3956.jpg" -"3957" "What feature is indicated by the darker brown granules in the dermis?" "Melanoma cells" "Hemosiderin deposition" "Calcium deposits" "Pigment incontinence" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3957.jpg" -"3958" "What does the morphology of the dermis in this histopathological image suggest?" "Dense sclerotic connective tissue" "Presence of abundant mucin" "Loose areolar connective tissue" "Predominantly myxoid stroma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3958.jpg" -"3959" "What is the architectural pattern exhibited by the cells in this image?" "Irregular, trabecular architecture" "Glandular formation with mucin production" "Disorganized with high pleomorphism" "Sheets of undifferentiated cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3959.jpg" -"3960" "What can be inferred about the cellular differentiation in this neuroendocrine tumor based on the visible morphology?" "High level of differentiation with little pleomorphism" "Undifferentiated with high mitotic index" "Poor differentiation with extensive necrosis" "Anaplastic features with numerous atypical mitotic figures" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3960.jpg" -"3961" "What is the morphology of the elongated and striated cells interspersed among the multinucleated larger cells?" "Striated muscle fibers resembling cardiac muscle with disarray" "Smooth muscle cells without striations" "Skeletal muscle fibers showing prominent striations" "Neuronal axons with myelin sheath" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3961.jpg" -"3962" "Which of the following features is NOT evident in the stromal compartment of the endometrial tissue sample?" "Prominent vascularization" "Dense population of spindle-shaped cells" "Signs of predecidualization" "Mitotic figures" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3962.jpg" -"3963" "Based on the visible cellular features in the image, which of the following is not observed?" "Mitotic figures" "Significant inflammatory infiltrate within the stroma" "Well-delineated nests surrounded by stroma without invasion" "Marked proliferation within the epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3963.jpg" -"3964" "What is the nuclear morphology of the epithelial cells present in the glandular structures?" "Pyknotic nuclei" "Anucleated cells" "Vesicular nuclei" "Hyperchromatic nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3964.jpg" -"3965" "Upon examination of the tissue, what is the most likely cellular composition of the densely packed areas?" "Mature adipocytes with large lipid droplets" "Basaloid cells with darkly stained nuclei" "Lymphocytes with scant cytoplasm" "Myoepithelial cells with clear cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3965.jpg" -"3966" "What is the overall pattern of cell distribution and stroma in this histologic image?" "Clusters of cells with minimal to no intervening stroma" "Dispersed cell clusters with a prominent fibrous stroma" "Homogenous population of cells with abundant myxoid stroma" "Disorganized growth with extensive necrotic areas" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3966.jpg" -"3967" "In the slide, which cells appear to indicate the presence of an inflammatory process?" "Plasma cells with eccentric nuclei" "Eosinophils with bright red granules" "Lymphocytes that are small round cells" "Macrophages with large irregular nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3967.jpg" -"3968" "What does the cellular arrangement within this tissue most closely resemble?" "Long interlacing cords" "Loose connective tissue" "Small follicles or acini" "Sheets of undifferentiated cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3968.jpg" -"3969" "Within the acinar structures, what can be identified in this image?" "Call-Exner bodies" "Hyaline cartilage" "Russel bodies" "Keratin pearls" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3969.jpg" -"3970" "What morphological feature does NOT align with a low-grade fibromyxoid sarcoma in this image?" "Striated muscle fibers" "Areas indicative of increased cellularity" "Myxomatous stroma" "Uniform fibrous and myxoid zones with a whorling pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3970.jpg" -"3971" "Based on the cellular morphology, what is the most likely location from which this tubular structure cross-section was taken?" "Esophagus" "Ureter" "Bronchus" "Fallopian tube" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3971.jpg" -"3972" "Based on the cellular morphology and the surrounding stroma, how would you classify the histological differentiation of the tissue?" "Poorly differentiated" "Well differentiated" "Cannot be determined" "Moderately differentiated" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3972.jpg" -"3973" "Based on the features observed in the image, what is the likely change noted in the stratum corneum of this epidermal section?" "Acantholysis" "Hyperkeratosis" "Parakeratosis" "Spongiosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3973.jpg" -"3974" "What is the predominant cellular morphology visible in this microscopic view?" "Lymphocyte-like cells with scant cytoplasm and round nuclei" "Elongated, fibroblast-like cells with spindle-shaped nuclei" "Small, uniform cells with low nuclear-to-cytoplasmic ratios" "Cells exhibiting marked pleomorphism with significant variation in size and shape" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3974.jpg" -"3975" "Based on the cellular morphology, which of the following cell types appear to be present in this image?" "Fibroblasts and epithelial cells" "Chondrocytes and osteocytes" "Adipocytes and melanocytes" "Neurons and glial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3975.jpg" -"3976" "Based on the morphological features observed, what can be inferred about the nature of the nuclei within the depicted cells?" "Euchromatic and homogeneous" "Hyperchromatic and pleomorphic" "Hypochromatic with uniform size" "Vesicular with prominent nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3976.jpg" -"3977" "Considering the appearance of the tissue architecture in the image, what can be inferred regarding its organization?" "The tissue architecture appears highly organized and uniform" "The tissue architecture is disrupted, suggesting a possible malignant infiltrate" "There is slight disorganization, but overall tissue structure is maintained" "The disruption in tissue architecture indicates regeneration and repair" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3977.jpg" -"3978" "What tissue architecture is observed in the microscope image that could suggest the type of tissue being examined?" "Glandular or trophoblastic tissue-reminiscent arrangements" "Striated muscle patterns" "Neuronal network structures" "Fibrous connective tissue arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3978.jpg" -"3979" "Based on the immunohistochemical staining pattern observed, which type of cellular architecture is prominently represented in this tissue sample?" "Spindle-shaped" "Solid" "Papillary" "Glandular" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3979.jpg" -"3980" "Focusing on the multinucleated giant cells within this tissue section, which statement best describes their nuclear arrangement?" "The nuclei are centrally clustered within the cytoplasm" "The nuclei form a horseshoe pattern around the cell periphery" "The nuclei are randomly dispersed throughout the cytoplasm" "The nuclei are aligned along one edge of the cell" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3980.jpg" -"3981" "Based on the histological features observed in the image, what type of necrosis is most likely present in the dermal layer?" "Caseous necrosis" "Fibrinoid necrosis" "Coagulative necrosis" "Liquefactive necrosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3981.jpg" -"3982" "Upon examining the tissue, what cellular changes are evident in the endothelial cells lining the blood vessels?" "Atrophy" "Metaplasia" "Hypertrophy" "Hyperplasia" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3982.jpg" -"3983" "The inflammatory cells interspersed among the hypertrophic endothelial cells are likely to be which types of cells based on their morphology?" "Monocytes and lymphocytes" "Eosinophils and macrophages" "Neutrophils and basophils" "Lymphocytes and eosinophils" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3983.jpg" -"3984" "What is the orientation of the nuclei within the columnar epithelial cells?" "Oriented perpendicular to the base membrane" "Oriented parallel to the base membrane" "Oriented at the apical surface" "Random orientation without a distinct pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3984.jpg" -"3985" "Assessing the glandular architecture, what is the structural complexity of the glands within the tissue?" "Glands with a relatively well-structured and simple shape" "Complete loss of glandular architecture with solid sheet formation" "Marked architectural complexity with frequent branching and budding" "Neoplastic glands with significant structural disorganization" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3985.jpg" -"3986" "When observing the fibrotic stroma within this tissue section, what characteristic coloration indicates dense collagen deposition?" "Blue to purple hue" "Pink to red hue" "Black to brown hue" "Green to yellow hue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3986.jpg" -"3987" "What is the appearance of the stroma within this tissue section?" "Fibrotic" "Necrotic" "Edematous" "Atrophic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3987.jpg" -"3988" "What type of cellular orientation pattern is discernible among the spindle-shaped cells within the tissue?" "Storiform pattern" "Alveolar pattern" "Nested pattern" "Palisading pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3988.jpg" -"3989" "The red-staining structures that are scattered throughout the image, what are these structures most likely representative of?" "Blood vessels" "Nerve fibers" "Smooth muscle fibers" "Erythrocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3989.jpg" -"3990" "What is the predominant cell shape observed in this high-power field of view?" "Spindle-shaped" "Round" "Polygonal" "Cuboidal" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3990.jpg" -"3991" "How would you describe the nuclei of the cells in this image?" "Blunt-ended or cigar-shaped" "Vesicular with prominent nucleoli" "Hyperchromatic with irregular borders" "Multiple nuclei per cell" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3991.jpg" -"3992" "In the central areas of the lobules, what type of keratinization is evident?" "Acantholytic keratinization" "Dyskeratotic keratinization" "Trichilemmal keratinization" "Orthokeratotic keratinization" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3992.jpg" -"3993" "Based on the organization of the tissue and presence of specific structures, what type of tissue is represented in the microscopic view?" "Dense irregular connective tissue" "Stratified squamous epithelium" "Nervous tissue" "Cardiac muscle tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3993.jpg" -"3994" "What type of tissue is primarily depicted in this microscopic image based on the arrangement and morphology of cells?" "Nervous tissue" "Epithelial tissue" "Adipose tissue" "Connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3994.jpg" -"3995" "What is the distinguishing feature of the stroma in the left side of the image?" "Cellular arrangement typical of cartilaginous tissue" "Its basophilic appearance with dispersed cells" "Dense eosinophilic connective tissue composition" "Glassy, homogeneous background structure" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3995.jpg" -"3996" "What type of cells predominate in the central area of the tissue section?" "Fibroblasts" "Epithelial cells" "Adipocytes" "Lymphocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3996.jpg" -"3997" "Identify the type of tissue located at the periphery of the image." "Adipose tissue" "Epithelial tissue" "Muscle tissue" "Nervous tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3997.jpg" -"3998" "What does the pink-stained background surrounding the elongated cells suggest about the tissue composition?" "Presence of dense regular connective tissue." "High cellular turnover and apoptotic bodies." "Presence of collagen fibers within the extracellular matrix." "Abundance of smooth muscle cells interspersed within the tissue." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3998.jpg" -"3999" "Analyzing the image, what type of tissue can be observed beneath the epithelial layer, characterized by a less dense and more fibrous appearance?" "Hyaline cartilage with chondrocytes" "Reticular dermis with thick collagen bundles" "Papillary dermis with thin collagen fibers" "Hypodermis with adipose cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/3999.jpg" -"4000" "In the provided microscopic image, what type of cells can be identified in the basal layer that are responsible for continuous regeneration of the epithelium?" "Keratinocytes at different maturation stages" "Squamous non-keratinized cells" "Spindle-shaped fibroblasts" "Columnar mitotically active cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4000.jpg" -"4001" "What type of cells can be recognized by the presence of dark granular pigment within their cytoplasm?" "Pigment-laden macrophages" "Melanocytes" "Langerhans cells" "Keratinocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4001.jpg" -"4002" "What does the variation in alveolar wall thickness observed in this sample suggest?" "Presence of atelectasis or processing artifacts" "Uniform lung function" "Development of fibrotic tissue" "Healthy lung parenchyma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4002.jpg" -"4003" "Based on the morphological changes present in this image, which condition is most likely represented?" "Acute inflammatory response" "Glycogen storage disease" "Cytomegalovirus (CMV) infection" "Lipid storage disorder" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4003.jpg" -"4004" "What is a distinctive morphologic feature of the nucleus within the highlighted large cell?" "It exhibits a ground-glass appearance with intranuclear inclusions." "It contains hyperchromatic stippling." "It shows multi-lobation." "It has a wrinkled or raisinoid appearance." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4004.jpg" -"4005" "Based on the density of the connective tissue observed in the image, what term best describes the appearance of the stroma?" "Loose connective tissue" "Reticular connective tissue" "Dense regular connective tissue" "Dense irregular connective tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4005.jpg" -"4006" "Based on the microscopic view, what is the most likely identity of the clear central spaces within the dermis?" "Keratinous cystic structures typical of epidermoid cysts." "Ductal lumens from eccrine sweat glands." "Sebaceous secretions within sebaceous glands." "Sarcomatoid features of spindled tumor cells." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4006.jpg" -"4007" "What is the predominant type of cell morphology visible in the specimen?" "Spindle-shaped cells with elongated nuclei" "Neoplastic cells with significant pleomorphism" "Adipocytes with large, vacuolated cytoplasm" "Lymphocytes with large, irregular nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4007.jpg" -"4008" "Which feature in the image is indicative of possible neoplastic transformation?" "Lack of significant pleomorphism or mitotic activity" "Presence of small, irregularly shaped spaces" "Presence of a collagenous matrix with pink staining" "Uniform appearance of spindle cells without atypia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4008.jpg" -"4009" "What characteristic is not evident in the extracellular matrix within this field?" "Clear evidence of lymphocytic infiltration" "Presence of red blood cells" "Disorganized distribution of the extracellular matrix" "Presence of eosinophilic (pink-staining) extracellular matrix" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4009.jpg" -"4010" "Based on the histological features observed, what is the most likely architectural change in the epithelial glands?" "Increased branching and variation in gland size" "Preservation of normal tubular architecture" "Uniform glandular size and shape with high polarization" "Loss of branching complexity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4010.jpg" -"4011" "What is the predominant staining characteristic of the epithelium lining the central structure?" "Eosinophilic with lighter-staining nuclei" "Basophilic with darker-staining nuclei" "Acidophilic with faintly visible nuclei" "Neutrophilic without distinct nuclear detail" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4011.jpg" -"4012" "How would you describe the arrangement of cells in the stroma external to the hair follicle-like structure?" "The cells are arranged randomly without a clear pattern" "The cells are organized in a tubular structure" "The cells exhibit a whorled pattern" "The cells form a sheet-like pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4012.jpg" -"4013" "What feature distinguishes this histological appearance from a trichoepithelioma?" "Presence of papillary mesenchymal bodies" "Lack of a prominent surrounding stroma" "Absence of papillary mesenchymal bodies" "Absence of a small cavity within the central follicle-like structure" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4013.jpg" -"4014" "What pattern of growth is visible in the cells of this microscopic image?" "Gland formation" "Indian file pattern" "Nesting pattern" "Rosette formation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4014.jpg" -"4015" "How would you describe the nuclei of the tumor cells observed in this tissue section?" "Pleomorphic and hyperchromatic" "Uniform and monomorphic" "Vesicular with prominent nucleoli" "Multinucleated with smudged chromatin" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4015.jpg" -"4016" "Based on the cellular morphology, what is the most likely identity of the cells with pale or cleared cytoplasm?" "Erythrocytes" "Adipocytes" "Neutrophils" "Histiocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4016.jpg" -"4017" "What is the distinguishing feature of the large cell in the center of the airspace?" "Single, large nucleus" "Lack of visible nuclei" "Multiple, crowded nuclei" "Multiple, dispersed nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4017.jpg" -"4018" "What does the surrounding pink-stained tissue most likely represent?" "Alveolar walls" "Muscular tissue" "Fibrous connective tissue" "Blood vessels" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4018.jpg" -"4019" "Identify the layer that contains the muscularis mucosae based on the structural organization seen in the image." "Above the glandular structures" "Below the glandular structures" "Within the lamina propria" "Adjacent to the finger-like projections" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4019.jpg" -"4020" "What is the most distinctive feature of the cells surrounding the clear spaces, or lumens, in the image?" "Reduplicated basement membrane" "Multilayered hyperchromatic nuclei" "Intracellular fat vacuoles" "Spindle-shaped mesenchymal cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4020.jpg" -"4021" "In the image, what does the region with densely packed cells with a darker staining pattern nested within a fibrous matrix most likely represent?" "Neoplastic proliferation" "Granulation tissue" "Skeletal muscle tissue" "Organized thrombotic material" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4021.jpg" -"4022" "Based on the tissue architecture and cellular morphology, how would the arrangement of the cells best be described?" "Loosely distributed with abundant extracellular matrix" "Organized in tightly packed glands" "Arranged in an irregular, papillary architecture" "Uniformly distributed with a well-defined basal layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4022.jpg" -"4023" "Based on the cellular morphology, what type of necrosis is most likely present in the central pale areas observed in this tissue section?" "Coagulative necrosis" "Liquefactive necrosis" "Fibrinoid necrosis" "Caseous necrosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4023.jpg" -"4024" "What type of inflammatory cells predominate at the periphery of the central necrotic areas?" "Eosinophils" "Lymphocytes" "Plasma cells" "Macrophages" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4024.jpg" -"4025" "In the given tissue section, how would you describe the overall cellularity?" "There is abundant cellularity with a high degree of cellular pleomorphism." "The cells appear uniform in size and shape, indicating a low-grade neoplasm." "The cellularity is sparse with abundant extracellular matrix." "The cellularity is moderate with well-differentiated cells." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4025.jpg" -"4026" "What is the appearance of the cytoplasm in the spindle-shaped cells observed in the image?" "The cytoplasm is scant and shows signs of vacuolation." "The cytoplasm is basophilic and granular." "The cytoplasm is eosinophilic and appears to be fibrillar." "The cytoplasm is abundant with clear perinuclear halos." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4026.jpg" -"4027" "When observing the stroma between the spindle-shaped cells, what is its most prominent characteristic in the image?" "The stroma consists of densely packed adipocytes." "There is a variable amount of pink-staining stromal collagen interspersed between the cells." "There is abundant myxoid stromal material separating the cells." "The stromal collagen is abundant and stains heavily with eosin." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4027.jpg" -"4028" "Upon examining the overall tissue architecture and cellular morphology, which finding is not prominent in this tissue sample?" "Disrupted tissue architecture due to pathology" "Necrotic or acellular eosinophilic material" "Large basaloid cell aggregates" "Atypical mitotic figures" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4028.jpg" -"4029" "How would you characterize the reaction of the stroma surrounding the basaloid cell nests in this histological sample?" "Minimal stromal reaction with occasional fibroblasts" "Lymphoid aggregates without evidence of granuloma formation" "Granulomatous inflammatory response with multi-nucleated giant cells" "Dense collagenous stroma with few inflammatory cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4029.jpg" -"4030" "What is the morphology of the inflammatory cells visible in this tissue section?" "Large cells with well-defined nuclear membranes and prominent nucleoli" "Cells with abundant eosinophilic (pink) cytoplasm" "Larger cells with pale cytoplasm and multiple nuclei" "Smaller cells with hyperchromatic (dark) and condensed nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4030.jpg" -"4031" "Based on the appearance of the collagen fibers within the field, how would you describe their organization?" "Densely packed and well-organized" "Uniform in thickness and parallel" "Regularly branched and networked" "Sparse and disorganized" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4031.jpg" -"4032" "Based on the histological features present in this image, what is the predominant alteration of epidermal thickness?" "Hyperplasia with increased epidermal thickness and elongated rete ridges" "Papillomatosis with upward projections of the epidermis" "Atrophy with decreased epidermal thickness" "Acanthosis with diffuse epidermal thickening without elongation of rete ridges" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4032.jpg" -"4033" "What is the most likely appearance of the nuclei in the given histopathological image?" "Large, eccentrically placed nuclei with dispersed chromatin" "Hypersegmented nuclei with condensed chromatin" "Round nuclei with multiple, prominent nucleoli" "Small, uniform nuclei with dense chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4033.jpg" -"4034" "Which cytoplasmic feature can be observed in the population of cells depicted in the image?" "Sparse cytoplasm with a lack of granularity" "Clear, vacuolated cytoplasm with peripheral condensation" "Abundant, dense, and homogenous eosinophilic cytoplasm" "Scant cytoplasm with intense basophilic staining" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4034.jpg" -"4035" "Which morphological pattern is NOT evident within the cellular structure presented in the image?" "Cohesive, syncytial cytoplasmic pattern" "Focal areas with spindle-shaped cells" "Tubular or glandular formation" "Rhabdoid morphology with the nucleus pushed to one side" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4035.jpg" -"4036" "The intercellular spaces in the central reticulated area seem to contain:" "Mucoid substance" "Keratin plugs" "Calcifications" "Fluidic substance" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4036.jpg" -"4037" "In the image, what does the basophilic background matrix indicate?" "Mesenchymal cells within a fibromatous or fibrous matrix" "Accumulation of extracellular matrix proteins" "Degenerated muscle tissue" "Aggregates of lymphoid tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4037.jpg" -"4038" "Observing the structural changes, what type of cell damage is inferred in the keratinocytes?" "Enlarged cells undergoing hyperplastic change" "Altered shape and pink appearance suggesting cytotoxicity" "Pyknotic nuclei indicative of irreversible damage" "Swelling of cells due to acute inflammation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4038.jpg" -"4039" "In the connective tissue layer below the epithelium, which type of inflammatory cells can be predominantly identified?" "Eosinophils" "Basophils" "Neutrophils" "Lymphocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4039.jpg" -"4040" "Based on the histological features observed in the provided image, which type of epithelium is present at the top of the image?" "Transitional epithelium" "Pseudostratified ciliated columnar epithelium" "Stratified squamous epithelium" "Simple columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4040.jpg" -"4041" "What does the clear space in the central portion of the image suggest?" "A glandular acinus" "A blood vessel" "A ductal structure" "An area of necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4041.jpg" -"4042" "What is the nature of the lymphocytic infiltrate observed at the dermoepidermal junction in the image?" "Absent" "Patchy and dense" "Dense and diffuse" "Patchy and not particularly dense" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4042.jpg" -"4043" "How does the chromatin within the nuclei of these cells appear?" "Absent or transparent" "Uniformly distributed but condensed" "Finely dispersed and evenly distributed" "Coarsely clumped and irregularly distributed" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4043.jpg" -"4044" "Based on the cellular organization, what can be inferred about the architecture of the tissue?" "The tissue shows abundant extracellular matrix and low cellular density" "The tissue lacks specialized architecture and appears densely packed" "The tissue is highly organized with clear cell differentiation" "The tissue displays specialized structures such as glands" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4044.jpg" -"4045" "What alteration in tissue organization is visible in this tissue sample?" "Regular sinusoidal spaces consistent with normal liver parenchyma" "Distinct fibrosis surrounding hepatocyte nodules" "White spaces resembling acinar or pseudoacinar structures" "Steatosis with clear lipid droplets within hepatocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4045.jpg" -"4046" "What characteristic feature is noted in the nuclei of the cells within this histologic section?" "Uniform nuclear size and shape" "Presence of multiple nucleoli within nuclei" "Hyperchromasia with darker staining than typical" "Clear evidence of binucleation in most cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4046.jpg" -"4047" "What cellular morphology is most evident in the thin elongated cords seen within the stroma?" "Small round cells with scant cytoplasm" "Uniform cells with small, regular nuclei" "Large cells with abundant cytoplasm and vacuolization" "Hyperchromatic nuclei with high nuclear-to-cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4047.jpg" -"4048" "How would you describe the areas where cells appear to be clustered or forming duct-like structures?" "Exhibiting squamous differentiation with keratin pearl formation" "Composed of uniform cells with large, vesicular nuclei" "Containing cells with pleomorphism and eosinophilic material" "Showing signet ring cells with mucinous cytoplasmic inclusions" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4048.jpg" -"4049" "Based on the tissue architecture, what is the most likely component of the pink to red-staining regions?" "Smooth muscle fiber" "Fibrin deposits" "Hyaline cartilage" "Collagenous stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4049.jpg" -"4050" "What does the stromal appearance in this tissue suggest?" "It has abundant adipose tissue" "It appears loose and edematous" "It is highly vascularized without inflammation" "It seems to be densely fibrous with inflammatory infiltrate" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4050.jpg" -"4051" "Based on the glandular architecture, what can you infer about the tissue's condition?" "There is a high level of pleomorphism in the glandular cells" "The glandular structures are uniform and well-formed" "The glandular structures are irregular in shape and size" "The glandular lumens are filled with secretion" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4051.jpg" -"4052" "In analyzing the histological features of this tissue, what is the most likely nature of the clear or white spaces observed?" "Glycogen accumulations within hepatocytes" "Lipid droplets within adipocytes" "Mucin deposits within the tissue" "Silicone deposits suspected in a foreign body reaction" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4052.jpg" -"4053" "What cellular feature in this image is indicative of an inflammatory response to the clear or white spaces?" "Presence of fibroblasts" "Presence of histiocytes" "Presence of lymphocytes" "Presence of neutrophils" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4053.jpg" -"4054" "Considering the pattern of growth and the morphology of the larger cells, which histopathological diagnosis is supported by this image?" "Dysgerminoma with a solid growth pattern" "Melanoma with dense pigmentation" "Liposarcoma with lipoblasts" "Adenocarcinoma with glandular differentiation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4054.jpg" -"4055" "Based on the cellular morphology, what is a prominent feature observed within the cells in some glandular structures?" "Abundant clear cytoplasm with peripheral nuclei" "Dense eosinophilic cytoplasm with centrally located nuclei" "Cytoplasmic vacuolation" "Cilia on the apical surface" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4055.jpg" -"4056" "What type of epithelial cell arrangement predominates in the glandular structures seen in the image?" "Pseudostratified columnar epithelium" "Simple cuboidal epithelium" "Simple squamous epithelium" "Stratified columnar epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4056.jpg" -"4057" "Based on the appearance of nuclei in these tissue cells, how would you describe their localization within the cells?" "Centrally located" "Peripheral location" "Irregularly scattered throughout the cytoplasm" "Multiple nuclei per cell" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4057.jpg" -"4058" "Judging by the cellular morphology in this tissue, how would you assess the differentiation of these cells?" "Anaplastic" "Poorly differentiated" "Well differentiated" "Moderately differentiated" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4058.jpg" -"4059" "What type of cellular alteration is predominantly observed in the provided tissue image?" "Hyperchromasia" "Monomorphism" "Hypochromasia" "Anisonucleosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4059.jpg" -"4060" "Based on the cellular organization seen in the image, what aspect of the tissue architecture remains preserved?" "Cellular cohesion" "Overall tissue disorganization" "Polarity of the cells" "Neoplastic transformation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4060.jpg" -"4061" "How would you characterize the epidermal changes observed in this skin section?" "Hyperkeratosis" "Parakeratosis" "Acantholysis" "Spongiosis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4061.jpg" -"4062" "What is the nature of the infiltrate surrounding the hair follicle-like structures?" "Eosinophilic" "Monocytic" "Lymphocytic" "Neutrophilic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4062.jpg" -"4063" "What type of epithelial cells predominantly lines this tissue section?" "Columnar epithelial cells" "Squamous epithelial cells" "Pseudostratified epithelial cells" "Stratified epithelial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4063.jpg" -"4064" "What is the predominant cytoplasmic characteristic of the epithelial cells lining the glands in the image?" "Sparse cytoplasm with hyperchromatic nuclei" "Abundant eosinophilic cytoplasm with rounded nuclei" "Cytoplasm with multiple vacuoles and signet ring appearance" "Abundant basophilic cytoplasm with pyknotic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4064.jpg" -"4065" "What is the appearance of the lumens in the glands as illustrated in the microscopic image?" "Empty lumens with no visible material" "Lumens filled with basophilic granular material" "Lumens filled with eosinophilic material" "Lumens containing keratin pearls" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4065.jpg" -"4066" "Considering the overall tissue architecture observed in the image, which statement is correct?" "There is a clear separation between the cells without direct contact, indicating individual spacing within the stroma." "The collagen appears as pink, anastomosing, thin fibrillar structures throughout the tissue." "The cells are arranged in a disorganized manner, indicative of high-grade malignancy." "There is a high degree of cellularity with cells being in direct contact with one another." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4066.jpg" -"4067" "Which phase of the endometrial cycle does this tissue most likely represent based on the structural features observed?" "Secretory phase" "Menstrual phase" "Late proliferative phase" "Early proliferative phase" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4067.jpg" -"4068" "What is the predominant type of inflammatory cell observed in the dense cellular infiltrate within this tissue section?" "Lymphocytes" "Macrophages" "Neutrophils" "Eosinophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4068.jpg" -"4069" "What additional pathological feature is visible in the tissue section apart from the cystic degeneration and dense inflammatory infiltrate?" "Angiogenesis" "Granuloma formation" "Caseous necrosis" "Squamous metaplasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4069.jpg" -"4070" "Upon examining the nuclei of the cells, what level of pleomorphism is observed?" "Severe nuclear pleomorphism with significant size variation" "High nuclear pleomorphism with bizarre and atypical nuclei" "Moderate nuclear pleomorphism with some variation in size and shape" "No nuclear pleomorphism" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4070.jpg" -"4071" "Which feature in the image suggests an acute rather than chronic inflammatory response?" "Eosinophilic infiltration" "Mononuclear cell predominance" "Large, central nuclei in the infiltrating cells" "Increase in multi-lobed nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4071.jpg" -"4072" "In the displayed image, the blood vessels located deeper in the tissue show a structure indicative of being:" "Large veins or arteries" "Lymphatic vessels" "Capillaries" "Arterioles" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4072.jpg" -"4073" "What pathology might the absence of adnexal structures in this skin sample suggest?" "Normal tissue variation" "Inflammatory destruction" "Technical artifact during sample preparation" "Early stage of development" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4073.jpg" -"4074" "What morphological feature is indicative of eosinophil degranulation in the tissue section observed?" "Blue-stained rounded structures with obscure nuclei" "Homogeneous pink areas without cellular definition" "Purple-stained elongated fibers running parallel to each other" "Bright red flame-like figures closely associated with collagen" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4074.jpg" -"4075" "Based on the microscopy image, what is the predominant cell type observed in the infiltrate?" "Large multinucleated cells" "Cells with small, dark nuclei and minimal cytoplasm" "Cells forming organized gland-like structures" "Cells with round to elongated nuclei and ample cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4075.jpg" -"4076" "Which characteristic of the epithelial cells on the luminal surface supports their function in absorption?" "Presence of cilia" "Uniform appearance and lack of specialized features" "High rate of cellular proliferation" "Presence of mucin-secreting goblet cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4076.jpg" -"4077" "What is the predominant nuclear staining pattern observed in the depicted cells?" "Homogeneous staining across all nuclei" "Heterogeneous staining with variation in intensity" "No nuclear staining" "Ring-like perinuclear staining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4077.jpg" -"4078" "Based on the histopathological appearance, what pattern of nuclear morphology is most frequently observed within these cells?" "Hyperchromatic nuclei with irregular borders" "Small, hyperchromatic nuclei with high nuclear-to-cytoplasmic ratio" "Uniform, small, and round nuclei with dense chromatin" "Enlarged nuclei with prominent nucleoli and open chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4078.jpg" -"4079" "What cytoplasmic changes are most notable in the tissue sample observed?" "Uniform eosinophilic cytoplasm with well-defined cell borders" "Cytoplasmic basophilia with no evidence of vacuolation" "Extensive cytoplasmic vacuolation throughout the tissue" "Presence of multiple large eosinophilic granules within the cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4079.jpg" -"4080" "Based on the histological features observed under the microscope, what best describes the arrangement of the nuclei within the ductal epithelial cells?" "Small and hypochromatic nuclei" "Enlarged and hyperchromatic nuclei" "Uniform nuclei with regular spacing" "Nuclei with pronounced nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4080.jpg" -"4081" "What is the predominant feature in the central area of the microscopic image?" "Spindle-shaped cells consistent with muscle tissue" "Amorphous eosinophilic material resembling fractured crystalline structures" "Uniformly spaced glandular structures" "Smooth homogenous basophilic material" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4081.jpg" -"4082" "Observing the tissue architecture, how would you describe the distribution of cells within the myxoid stroma?" "There is a low density of cells sparsely scattered throughout the stroma." "There is a low density of cells primarily clustered around vessels." "There is a high density of cells forming distinct nodular aggregates." "There is a high density of cells evenly distributed throughout the stroma." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4082.jpg" -"4083" "Assessing the overall architecture of the depicted renal tissue, which statement best describes the observed changes?" "The mesangial regions appear widened with potential compression of capillary loops" "The glomerular basement membrane appears thickened and double contoured" "Hypercellularity is evident in the glomeruli due to an increase in endocapillary cells" "There is significant neutrophilic infiltration within the glomeruli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4083.jpg" -"4084" "Based on the histological characteristics observed in the image, which epidermal layer appears to be thickened?" "Stratum spinosum" "Stratum corneum" "Stratum granulosum" "Stratum basale" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4084.jpg" -"4085" "What is the predominant stroma characteristic seen in this microscopic image?" "Myxoid stromal changes" "Densely packed collagen fibers" "Adipose tissue infiltration" "Abundant angiogenesis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4085.jpg" -"4086" "Based on the arrangement and morphology of the cells lining the luminal structure, which of the following best describes the histological feature?" "Pseudostratified ciliated columnar epithelium" "Transitional epithelium with umbrella cells" "Stratifed columnar epithelium with dysplasia" "Squamous epithelium with keratinization" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4086.jpg" -"4087" "Based on the microscopic features observed, what type of tissue predominates in the central area of this image?" "Adipose tissue" "Neural tissue" "Skeletal muscle tissue" "Collagenous connective tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4087.jpg" -"4088" "What pattern is most predominantly displayed by the nuclei of the cells in the tissue?" "Vesicular nuclei with prominent nucleoli" "Monotonous pattern with uniform nuclear size" "Hobnail pattern with apically positioned nuclei" "Hyperchromatic nuclei with a cramped arrangement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4088.jpg" -"4089" "Based on the organization of the epithelial cells lining the cystic spaces, which glandular structure do they most likely represent?" "Sebaceous gland" "Thyroid gland" "Sweat gland" "Salivary gland" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4089.jpg" -"4090" "What does the peripheral region of the tissue slide predominantly indicate?" "Highly cellular area with osteoid structures suggesting new bone formation" "Presence of adipocytes indicating adipose tissue development" "Myofibers with cross striations representing skeletal muscle tissue" "Necrotic tissue indicating a degenerative process" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4090.jpg" -"4091" "What type of nuclear chromatin can be observed in the lymphocyte indicated by the arrow?" "Pycnotic (clumped staining)" "Heterochromatic (dark staining)" "Euchromatic (light staining)" "Aneuchromatic (no staining)" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4091.jpg" -"4092" "Based on the image, what is the mitotic activity level of the cells?" "High mitotic index with numerous mitotic figures" "Cannot be determined as mitotic figures are not visible" "Moderate mitotic activity with occasional mitotic figures" "Low mitotic activity without prominent mitotic figures" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4092.jpg" -"4093" "Based on the morphology of the tubular structures in the image, what type of epithelium is predominantly observed?" "Pseudostratified columnar epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Transitional epithelium" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4093.jpg" -"4094" "Identify the structures in the dermis that resemble round to oval shapes with hollow centers located deeper within the tissue section seen predominantly in the left portion of the image:" "Hair follicles and associated sebaceous glands" "Blood vessels" "Sweat glands" "Pacinian corpuscles" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4094.jpg" -"4095" "Based on the histopathological features observed in the image, what can be noted about the stratum corneum of the epidermal layer?" "The stratum corneum is exaggerated and thickened" "The stratum corneum shows signs of spongiosis" "The stratum corneum is thin and inconspicuous" "The stratum corneum displays atrophy" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4095.jpg" -"4096" "In evaluating the blood vessels within the stroma, which of the following observations is most accurate?" "They are large and irregularly shaped" "There is evidence of extensive angiogenesis with small budding vessels" "They display regular size and shape throughout the tissue" "They are uniformly small and thin-walled" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4096.jpg" -"4097" "Based on the observed histopathology, how would you characterize the overall integrity of the alveolar walls in this lung tissue sample?" "Disrupted in some areas" "Intact with clearly delineated borders" "Uniformly healthy across the sample" "Thickened and fibrotic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4097.jpg" -"4098" "What is the most prominent characteristic of the larger cells in the image that indicates a pathologic alteration?" "Uniform cytoplasm and small nuclei" "Scant cytoplasm and large nuclei" "Small, uniform vacuoles" "Abundant foamy cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4098.jpg" -"4099" "The smaller, blue cells surrounding the larger cells demonstrate a certain type of nuclear feature. What is this feature?" "Clearing of nuclear chromatin" "Multinucleation" "Hyperchromasia" "Macronucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4099.jpg" -"4100" "Based on the spindle-shaped morphology of the cells in the image, which of the following features is NOT evident?" "There is absence of significant mitotic activity" "Cells contain elongated nuclei" "The organization of the spindle cells is somewhat patterned" "The cells exhibit a high degree of nuclear pleomorphism" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4100.jpg" -"4101" "What can we infer about the tissue's extracellular matrix in contrast with the spindle cells' cytoplasm?" "Both the extracellular matrix and cytoplasm appear equally eosinophilic" "The extracellular matrix stains more eosinophilic than the cytoplasm" "The extracellular matrix stains less eosinophilic than the cytoplasm" "There is no visible extracellular matrix present" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4101.jpg" -"4102" "What is represented by the pink matrix within the image?" "Non-mineralized bone matrix" "Cartilaginous tissue" "Mineralized bone matrix" "Soft connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4102.jpg" -"4103" "Based on the image provided, which regions are likely to be occupied by osteoblasts during bone formation?" "Along the perimeter of the bone tissue" "Areas indicated by black arrows" "Within the large pink matrix" "Inside the circular areas pointed by blue arrows" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4103.jpg" -"4104" "Which feature is predominant in the cellular morphology of the tissue presented in the image?" "Uniform cells with hyperchromatic nuclei forming duct-like structures" "Spindle-shaped cells with a disorganized arrangement" "Round and cohesive cells with abundant cytoplasm" "Large polygonal cells organized in nests or acini" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4104.jpg" -"4105" "What type of tissue can be identified at the bottom of this image?" "Stratified squamous epithelium" "Adipose tissue" "Skeletal muscle" "Dense irregular connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4105.jpg" -"4106" "In the right portion of the image, how would you describe the arrangement of the spindle cells with hyperchromatic nuclei?" "Organized in a whorled pattern" "Arranged in a syncytial configuration" "Dispersed within the collagen-rich stroma" "Clustered in a microalveolar pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4106.jpg" -"4107" "Assessing the overall cellular organization, which histopathological feature is most accurately represented in the epithelial elements of the tissue?" "Pleomorphic nuclei with significant size variation" "Uniform nuclei with some showing hyperchromasia" "Disorganized growth pattern" "Presence of numerous mitotic figures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4107.jpg" -"4108" "Which characteristic indicates a likely inflammatory response in the underlying connective tissue?" "Sparse distribution of cells with small, hyperchromatic nuclei" "Abundance of cells with small, light-staining nuclei and high cytoplasmic content" "Presence of cells with denser, darker-staining nuclei" "Dense clusters of cells with enlarged, hyperchromatic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4108.jpg" -"4109" "Based on the image organization and architecture, which anatomical site can this tissue most likely correspond to?" "The lining of a glandular duct" "The transitional epithelium of the urinary bladder" "The mucosal surface such as oral or esophageal lining" "The inner lining of a blood vessel" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4109.jpg" -"4110" "In assessing the degree of cellular atypia within this field, which feature is LEAST likely to be associated with the specimen shown?" "Mild nuclear enlargement" "Mild variation in cell size and shape" "Presence of a single, prominent nucleoli" "Significant pleomorphism" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4110.jpg" -"4111" "How does the extracellular matrix of the interstitial tissue appear in this sample of adipose tissue?" "Red-staining with fragmented fibers" "Blue-staining with thin, straight fibers" "Green-staining with reticular fibers" "Pink-staining with thick, wavy fibers" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4111.jpg" -"4112" "The arrangement of collagen fibers in this image is indicative of:" "An overall high cellularity apart from the adipocytes" "A sporadic, inconsistent pattern with pockets of dense eosinophilic structures" "Predominantly inflammatory features scattered across the tissue" "A consistent, homogenous pattern throughout the tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4112.jpg" -"4113" "Which of the following best describes the arrangement of the epithelial cells within this tissue sample?" "Indian file pattern" "Solid nests and strands" "Diffuse infiltration" "Single-file arrangement" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4113.jpg" -"4114" "What are the eosinophilic bodies called that are observed within the tissue context?" "Psammoma bodies" "Russell bodies" "Kamino bodies" "Howell-Jolly bodies" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4114.jpg" -"4115" "What is the morphological appearance of the nuclei in the large central cell?" "Large and vesicular with prominent nucleoli" "Hypochromatic and round" "Ovoid and elongated with moderately dense chromatin" "Hyperchromatic and fragmented" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4115.jpg" -"4116" "Judging by the cytoplasmic characteristics of the cells, what type of extracellular matrix does the image likely represent?" "Myxoid" "Lipid-rich" "Eosinophilic and fibrous" "Chondroid" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4116.jpg" -"4117" "Considering the tissue morphology seen in the image, which feature is most consistent with the stromal component?" "Abundant specialized structures such as well-defined blood vessels" "Highly organized and differentiated stromal tissue" "Sparse stroma without specialized structures" "Dense and fibrous connective tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4117.jpg" -"4118" "What histological feature is most indicative of solar elastosis in this skin tissue section?" "Areas of amorphous, blurry basophilic material in the dermis" "Fine, wavy, eosinophilic appearance of dermal fibers" "Presence of a centralized hair follicle" "Accumulation of melanin in the basal layer" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4118.jpg" -"4119" "Based on the histological features, how does the epidermis respond to solar damage in this image?" "Hyperkeratosis of the stratum corneum" "Decrease in the number of Langerhans cells" "Hyperpigmentation within its basal layer" "Thinning of the epidermal layer" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4119.jpg" -"4120" "Considering the mesangial regions in this image, which of the following statements is true?" "Mesangial areas contain cells with prominent nuclei and no signs of proliferation." "There is an obvious increase in the number of mesangial cells (hypercentrality)." "The mesangial cells exhibit characteristics of apoptosis with cell shrinkage and fragmentation." "The mesangial regions display signs of disproportionate matrix accumulation." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4120.jpg" -"4121" "Which of the following descriptions best matches the nuclear characteristics of the cells in this image?" "Uniform, small, and hypochromatic nuclei" "Bi-nucleated cells with prominent nucleoli" "Hyperchromatic and pleomorphic nuclei" "Large nucleoli with surrounding halo" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4121.jpg" -"4122" "How would you describe the cytoplasmic features of the cells in this tissue section?" "Basophilic cytoplasm with abundant ribosomes" "Vacuolated cytoplasm with a foamy appearance" "Clear cytoplasm with signet ring cell morphology" "Eosinophilic and granular cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4122.jpg" -"4123" "In the given image, how would you describe the arrangement of the lymphocytes within the dermis?" "Predominantly perivascular" "Diffuse and evenly distributed" "Confined to the superficial dermis" "Nodular or aggregated, especially in the deeper portions" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4123.jpg" -"4124" "Based on the cellular organization and morphology observed in this image, what is the most likely condition represented?" "Papillary urethral hyperplasia" "Normal urothelium" "Urothelial carcinoma" "Squamous metaplasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4124.jpg" -"4125" "Analyzing the tissue architecture, which term best describes the arrangement of these cells?" "Well-demarcated" "Monolayered organization" "Disrupted arrangement" "Organized glandular pattern" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4125.jpg" -"4126" "What characteristic feature can be observed in the nuclei of the cells indicated by the arrows?" "Hyperchromasia" "Prominent nucleoli" "Multinucleation" "Basophilic intranuclear inclusions" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4126.jpg" -"4127" "In Figure 2, what is the key identifying feature of the structures encircled in red?" "Oval shape with a darker outline and lighter center, indicative of eggs" "Amorphous crystalline structures without specific morphology" "Presence of motile trophozoites" "Thick-walled cysts with multiple daughter cysts inside" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4127.jpg" -"4128" "In Figure 3, what types of leukocytes are predominantly circled in yellow?" "Eosinophils with bilobed nuclei, characteristic of eosinophils" "Macrophages with kidney shaped nuclei" "Neutrophils with multi-lobed nuclei" "Lymphocytes with large, singular nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4128.jpg" -"4129" "Analyzing the stromal component surrounding the tubular structure, what pattern do the cells exhibit?" "Highly structured arrangement resembling normal tissue architecture" "Densely packed cells with minimal extracellular space" "Cells with elongate nuclei arranged in a vesicular pattern" "Regular arrangement with homogenous cellular morphology" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4129.jpg" -"4130" "What is the predominant cellular arrangement observed in this microscopic image?" "Sheets of spindled cells" "Organoid nesting around blood vessels" "Dispersed single cells with abundant stroma" "Anarchic growth without any distinct pattern" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4130.jpg" -"4131" "What type of epithelial cell arrangement is observed in the tissue specimen?" "Stratified squamous" "Simple columnar" "Pseudostratified ciliated" "Transitional" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4131.jpg" -"4132" "Based on the presence of the observed tissue characteristics, which organ is this tissue most likely derived from?" "Trachea" "Urinary bladder" "Small intestine" "Skin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4132.jpg" -"4133" "Focusing on the chromatin pattern within the cells in this image, which of the following descriptions most accurately characterizes the majority of the nuclei observed?" "Open chromatin pattern with evident nucleoli" "Course chromatin with small indistinct nucleoli" "Condensed chromatin with no visible nucleoli" "Hyperchromatic nuclei with smudged chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4133.jpg" -"4134" "What can be inferred about the interstitial spaces visible in this image?" "They exhibit extensive necrotic debris" "They are devoid of any cellular elements" "They contain abundant lymphocytic infiltrate" "They house small, round, eosinophilic structures likely representing erythrocytes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4134.jpg" -"4135" "Considering the placement of nuclei within the cells in this image, which description is most accurate?" "Mostly centrally located nuclei without significant pleomorphism" "Nuclei showing significant pleomorphism" "Nuclei mostly located at the periphery" "Multinucleation in most of the cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4135.jpg" -"4136" "What is the characteristic morphological feature of the cells within the circled area in the microscopic image?" "Eccentrically located nuclei with cytoplasmic vacuolation" "Small, hyperchromatic nuclei" "Cells with multiple nuclei" "Uniform cell size and shape" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4136.jpg" -"4137" "Based on the image, how would you describe the nuclei of the cells in terms of their chromatin pattern and nuclear placement?" "Marginally placed with hyperchromatic appearance" "Marginally placed with densely clumped chromatin" "Centrally located with evenly dispersed chromatin" "Centrally located with nucleoli visible" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4137.jpg" -"4138" "What is the morphology of the glomerular capillary loops in the central glomerulus?" "Tortuous with regions of increased pink staining" "Widely spaced with reduced matrix material" "Regular and uniform" "Collapsed with decreased cellularity" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4138.jpg" -"4139" "What feature of the interstitial tissue is most apparent in this image?" "Accumulation of adipose tissue within the interstitium" "Decreased cellularity compared to normal renal interstitium" "Increased cellularity that could include inflammatory cells" "Presence of homogeneous acellular material indicative of interstitial fibrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4139.jpg" -"4140" "The elongated, thin extension in the center of the image is likely what type of structure?" "Muscle fiber" "Venous valve" "Epithelial fold" "Nerve fiber" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4140.jpg" -"4141" "What tissue component is interspersed among the spindle-shaped cells?" "Adipocytes" "Hematopoietic cells" "Hyaline cartilage" "Smooth muscle cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4141.jpg" -"4142" "What evidence of maturation with depth can be identified in the pigmented lesion depicted in the image?" "A clear boundary between the epidermis and the dermis with no intermixing of cells" "Larger and darker-stained melanocytes as they descend deeper into the dermis" "The deepest part of the dermis showing the most substantial melanin production" "Smaller cells with increased melanin pigment descending into the dermis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4142.jpg" -"4143" "Based on the morphology, what type of cells most likely represent the darker staining nuclei dispersed throughout the image?" "Red blood cells" "Fibroblasts or Schwann cells" "Osteocytes" "Epithelial cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4143.jpg" -"4144" "What does the architectural pattern of the cells in the image suggest?" "Neoplastic growth" "Normal tissue" "Acute inflammation" "Reactive or regenerative process" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4144.jpg" -"4145" "Which type of epithelial tissue is seen at the bottom layer of this microscopic image?" "Transitional epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "Simple squamous epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4145.jpg" -"4146" "Analyzing the tissue section, what observation can be made about the stroma?" "The stroma is dense and fibrous, possibly indicating sclerosis." "The stroma shows a high degree of adipose tissue infiltration." "There is evidence of extensive hemorrhage within the stromal compartments." "The stroma appears myxoid with scattered inflammatory cells." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4146.jpg" -"4147" "What other type of cells can be identified in this tissue section in addition to the predominant cell type?" "Endothelial cells" "Osteocytes" "Neutrophils" "Plasma cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4147.jpg" -"4148" "What type of nuclear variability is evident in this microscopic image?" "Pleomorphism" "Anisokaryosis" "Anisocytosis" "Hyperchromasia" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4148.jpg" -"4149" "Upon examining the cells' cytoplasm, which features are consistent with a diagnosis of rhabdoid tumor?" "Clear halo surrounding the nucleus" "Small, darkly stained cytoplasmic granules" "Large eosinophilic inclusions within the cytoplasm" "Numerous tiny vacuoles scattered throughout the cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4149.jpg" -"4150" "Based on the chromatin pattern observed in this image, what is suggested about the nature of these cells?" "Coarse chromatin associated with malignant cells" "Fine, evenly dispersed chromatin typical of benign cells" "Chromatin condensation consistent with apoptotic cells" "Clumped chromatin seen in senescent cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4150.jpg" -"4151" "What does the presence of dark brown nuclear staining indicate in this image?" "Hematoxylin staining without specific markers" "Immunoreactivity with Ki-67 antigen, indicating cell proliferation" "Necrotic cell death" "Presence of lipid accumulation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4151.jpg" -"4152" "What can be inferred regarding the tissue origin of the neoplastic cells in this image?" "Neuroectodermal origin due to immunoreactivity for specific neural markers" "Epithelial origin due to gland-like structures" "Hematopoietic origin due to the presence of blood cells" "Mesodermal origin due to the presence of muscle fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4152.jpg" -"4153" "What is the morphology of the nuclei in the cells closest to the surface layer of this stratified epithelium?" "Irregularly shaped and hyperchromatic" "Large, round, and euchromatic" "Elongated and spindle-shaped" "Small, round, and pyknotic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4153.jpg" -"4154" "How are the smooth muscle fibers oriented in the deeper tissue layers presented in this image?" "Cut in cross-section, round appearance" "Parallel to the surface of the epithelium" "Perpendicular to the surface of the epithelium" "In multiple directions, creating a woven appearance" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4154.jpg" -"4155" "What morphological feature observed in the image supports a potential diagnosis of ductal carcinoma in situ (DCIS)?" "Presence of dense stromal connective tissue" "Areas of necrosis" "Lack of obvious invasion into the surrounding tissue" "Structures that resemble papillary formations with architectural disorder" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4155.jpg" -"4156" "Analyzing the connective tissue layer, what type of structure is predominantly exhibited by the fibrous component?" "Elastic fibers in a parallel arrangement" "Adipose tissue clusters" "Regularly aligned collagen bundles" "Dense irregular connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4156.jpg" -"4157" "What is the predominant characteristic of the nuclei observed in the cells within this microscopic image?" "Small, hyperchromatic nuclei with scant cytoplasm" "Large nuclei with vesicular chromatin" "Multinucleation with significant atypia" "Hyperchromasia with high nucleus-to-cytoplasm ratio" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4157.jpg" -"4158" "Based on the morphology of the cells, how would you characterize the chromatin pattern in the nuclei?" "Clumped and condensed" "Homogenous and dense throughout" "Vesicular with a speckled appearance" "Unevenly dispersed with large areas of clearing" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4158.jpg" -"4159" "Based on the morphology observed in the image, what is the predominant cell type within the central lighter staining region?" "Adipocytes" "Hematopoietic Cells" "Chondrocytes" "Osteocytes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4159.jpg" -"4160" "What does the denser pinkish material primarily surrounding the central area of the bone marrow signify?" "Hyaline cartilage" "Osteoid matrix" "Cortical bone" "Trabecular bone" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4160.jpg" -"4161" "Based on the cellular morphology visible in the image, which type of secretion process is most likely occurring in the glandular epithelium?" "Endocrine" "Holocrine" "Merocrine" "Apocrine" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4161.jpg" -"4162" "Based on the histopathological features observed in the epidermis of this skin tissue section, which description best characterizes the distribution and morphology of the pigmented cells?" "Concentrated entirely within the subcutaneous tissue with no epidermal involvement" "Scattered throughout both basal and superficial layers without clear maturation" "Clustered in the basal layer with clear delineation from the upper layers" "Uniformly distributed with a progressive decrease in pigmentation towards the surface" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4162.jpg" -"4163" "Focusing on the appearance of the epidermal cells, which choice best reflects the pigmentation pattern and the potential diagnostic relevance present in the image?" "Lacking melanocytes suggestive of a vitiligo diagnosis" "Even pigmentation indicative of a benign nevus" "Asymmetry and variability in pigmentation hinting at a dysplastic nevus" "Increased pigmentation and abnormal localization suggestive of melanoma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4163.jpg" -"4164" "Based on the glandular pattern observed in this tissue, which architectural feature predominates?" "Cystic" "Cribriform" "Papillary" "Simple tubular" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4164.jpg" -"4165" "Considering the nuclear features of the epithelial cells lining the glands, which description is most accurate?" "Vesicular nuclei with small, central nucleoli" "Small, round nuclei with inconspicuous nucleoli" "Uniform nuclei with fine chromatin" "Enlarged nuclei with prominent nucleoli and hyperchromasia" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4165.jpg" -"4166" "What is the staining quality of the stromal tissue present in this microscopic field?" "Abundant and eosinophilic" "Scarce and eosinophilic" "Abundant and basophilic" "Scarce and basophilic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4166.jpg" -"4167" "Considering the cells with irregularly shaped and rounded nuclei, what could be inferred about the central structure surrounded by these cells?" "Sebaceous gland" "Sweat duct" "Melanocytic nevus" "Hair follicle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4167.jpg" -"4168" "Based on the varied appearance of the round droplets that lack staining, what can be inferred about the nature of the material observed?" "Highly polar and water-soluble" "Endogenous lipid accumulation" "Exogenous substance like silicone" "Heavily calcified deposits" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4168.jpg" -"4169" "What type of cartilage is evident based on the presence of chondrocytes within lacunae and the extracellular matrix appearance?" "Elastic cartilage" "Hyaline cartilage" "Fibrocartilage" "Myxoid cartilage" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4169.jpg" -"4170" "What does the morphology of the cells' cytoplasm suggest in this microscopic image?" "The cells have abundant, well-defined cytoplasm" "Cytoplasmic boundaries are readily identifiable and regular" "Cytoplasm shows evidence of significant vacuolization" "The cytoplasm is scant and basophilic" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4170.jpg" -"4171" "What type of secretion can be observed within the glandular structures in the image?" "Eosinophilic" "Serous" "Mucinous" "Basophilic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4171.jpg" -"4172" "Based on the organized columnar structure of the cells in this tissue image, which stage of chondrocyte development are these cells likely undergoing?" "Early proliferation" "Quiescence" "Hypertrophic maturation" "Terminal differentiation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4172.jpg" -"4173" "What is the most prominent abnormal histological feature observed in the submucosal layer?" "Fibrotic tissue" "Dense inflammatory infiltrate" "Foreign body multinucleated giant cells" "Cystically dilated spaces likely representing air" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4173.jpg" -"4174" "In the assessment of the muscularis propria, what is the observed condition?" "Presence of foreign material" "Retained integrity of muscle layers" "Disruption of the muscle layer" "Signs of neoplastic infiltration" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4174.jpg" -"4175" "What type of epithelium lines the lumen of the tubular structure shown in the image?" "Simple squamous epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "Transitional epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4175.jpg" -"4176" "Based on the tissue architecture observed in the image, what is the likely functionality of the surface epithelial cells?" "Secretion" "Absorption" "Distension and contraction" "Filtration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4176.jpg" -"4177" "Based on the histological features observed, what type of cells predominantly compose the tissue in the image?" "Endothelial cells" "Adipocytes" "Squamous epithelial cells" "Smooth muscle cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4177.jpg" -"4178" "The areas of more densely packed, lighter-staining regions in the image are likely to be composed of which structure?" "Nervous tissue" "Adipose tissue" "Dense collagenous connective tissue" "Skeletal muscle" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4178.jpg" -"4179" "What does the presence of cells with darker-staining nuclei interspersed within the tissue likely represent?" "Fibroblasts" "Neutrophils" "Keratinocytes" "Erythrocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4179.jpg" -"4180" "What is the predominant type of tissue arrangement visible in the epithelial structures?" "Single layer of columnar cells" "Stratified squamous epithelium" "Cords or structures with branching patterns" "Sheets of pleomorphic cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4180.jpg" -"4181" "What is the appearance of the nuclei in the basal layer of the epithelial cells?" "Large, hyperchromatic, and irregular" "Dark, round to oval" "Small, hyperchromatic, and spindle-shaped" "Vesicular with prominent nucleoli" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4181.jpg" -"4182" "What is the appearance of the stroma in the image?" "Myxoid with sparse cellularity" "Lymphocytic infiltrate" "Eosinophilic and fibrous" "Hemorrhagic with red blood cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4182.jpg" -"4183" "Based on the cellular architecture observed, what is a likely origin of the tissue?" "Glandular or ductal epithelium" "Skeletal muscle showing striations" "Adipose tissue with prominent adipocytes" "Nervous tissue displaying glial cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4183.jpg" -"4184" "Evaluating the nuclear morphology, which feature stands prominent in the analysis of this stratified squamous epithelium?" "Small, rounded nuclei with inconspicuous nucleoli" "Small hyperchromatic nuclei uniformly distributed" "Regularly contoured nuclei with uniform chromatin distribution" "Enlarged nuclei with irregular nuclear outlines" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4184.jpg" -"4185" "Regarding the cytoplasmic changes visible in the cells, what characteristics are observed?" "Dense and basophilic cytoplasm" "Eosinophilic cytoplasm with numerous vacuoles" "Clear cytoplasm with a perinuclear halo" "Granular cytoplasm with multiple dark inclusions" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4185.jpg" -"4186" "What is the nuclear appearance of the cells in the given microscopic image?" "Round to ovoid and uniformly spaced" "Multilobed and hyperchromatic" "Enlarged and irregular with high nuclear-cytoplasmic ratio" "Pleomorphic with prominent nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4186.jpg" -"4187" "How can the stromal component of this tissue be best described based on this image?" "Dense, hyalinized and acellular" "Fibrous with loose connective tissue" "Myxoid with high cellularity" "Desmoplastic reaction with abundant fibroblasts" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4187.jpg" -"4188" "Which feature, often present in reactive or pathological lymph nodes, is not clearly distinguishable at this magnification in the image?" "Distinct germinal centers" "Regions of extranodal extension" "Granular histiocytic cells" "Dense clusters of lymphocytes" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4188.jpg" -"4189" "What is the pattern of organization of the cells within this tissue?" "Cells are predominantly forming glandular structures" "Cells are mostly organized in single-file arrangements" "Cells are mostly dispersed with no distinctive pattern" "Cells are arranged in a palisading pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4189.jpg" -"4190" "What is the appearance of the stroma surrounding the tubular structures?" "Hyalinized connective tissue with calcifications" "Adipose tissue with high vascularity" "Loose connective tissue with abundant inflammatory infiltrate" "Dense connective tissue with scattered spindle-shaped fibroblasts" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4190.jpg" -"4191" "The intercellular boundaries within the nodule can be described as:" "Well-defined with uniform spacing" "Loose, lacking a structured pattern and consistent spacing" "Absent with syncytial arrangement of cells" "Well-defined with cellular cohesion similar to benign nevi" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4191.jpg" -"4192" "Based on the tissue morphology observed, which layer of the epidermis is best represented in this image?" "Stratum granulosum" "Stratum corneum" "Stratum basale" "Stratum spinosum" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4192.jpg" -"4193" "In the provided image, the cells that are closest to the lumen of the seminiferous tubules exhibit what kind of staining?" "They are larger and feature a bright eosinophilic staining" "They exhibit neutral staining without basophilia or eosinophilia" "They appear with clear cytoplasm and no visible nucleus" "They are smaller and more basophilic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4193.jpg" -"4194" "What is the appearance of the nuclei of the large cells with abundant cytoplasm in the image on the left?" "Eccentric with a foamy cytoplasm" "Small and hyperchromatic" "Hyperchromatic and clustered" "Large and multiple within a single cell" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4194.jpg" -"4195" "What does the presence of brownish granular pigment within the cytoplasm of cells in the left image suggest?" "Melanin accumulation" "Hemosiderin deposition" "Lipofuscin deposition" "Calcification" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4195.jpg" -"4196" "In the image on the right, what is the most likely cause of the obliteration of alveolar spaces?" "Overdistension of alveoli due to air trapping" "Neoplastic cell proliferation" "Accumulation of macrophages with engorged cytoplasm" "Fibrotic changes leading to alveolar collapse" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4196.jpg" -"4197" "Based on the microscopic characteristics of the muscle tissue presented, what type of muscle tissue is depicted?" "Smooth muscle tissue" "No muscle tissue is present" "Skeletal muscle tissue" "Cardiac muscle tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4197.jpg" -"4198" "Based on the appearance of the cytoplasm in the cells, what histological feature is evident?" "Diffuse basophilia indicating high RNA content" "Abundant eosinophilic inclusions suggestive of granular cytoplasm" "Multiple clear vacuoles or lipid deposits" "Dark pigmentation consistent with melanin" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4198.jpg" -"4199" "Based on the histologic features observed, what is the most likely morphology of the mucosal surface in this image?" "Presence of rugal folds" "Flattened mucosal surface" "Presence of villus-like projections" "Presence of prominent goblet cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4199.jpg" -"4200" "What is the nature of the cytoplasmic pigmentation observed in the cells within the presented tissue section?" "Melanin deposition" "Hemosiderin accumulation" "Glycogen deposits" "Lipofuscin granules" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4200.jpg" -"4201" "Considering the stromal features between the structures observed, which of the following best describes the stroma?" "Scant and composed of loose connective tissue" "Rich in adipose tissue with vascular proliferation" "Dense and collagenous with fibroblastic proliferation" "Featuring granulomatous inflammation with multi-nucleated giant cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4201.jpg" -"4202" "When looking at the stratum corneum in this image, what characteristic feature supports the diagnosis of verruca?" "Compact orthokeratosis" "Clusters of dark purple-stained cells" "Basket-weave orthokeratosis" "Scale crust formation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4202.jpg" -"4203" "Observing the arrangement of cells within the cartilaginous matrix, how would you describe their distribution?" "Uniformly distributed" "Stratified in parallel rows" "Clustered in groups" "Irregularly distributed" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4203.jpg" -"4204" "What diagnostic feature can be noted within the fields of spindle-shaped cells?" "Inclusion bodies within the cellular cytoplasm" "Small, blood-filled spaces or areas of hemorrhage" "Multiple mitotic figures indicative of high proliferative activity" "Large areas of necrosis within the cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4204.jpg" -"4205" "How would you describe the stroma within which the cells are embedded?" "Densely collagenous with a pink hue" "Myxoid with a gelatinous appearance" "Lipid-rich with vacuolated spaces" "Hyalinized with a glassy, homogenous texture" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4205.jpg" -"4206" "Based on the cellular morphology, what feature is consistent with the description of the nuclei within the densely packed cellular regions of the tissue?" "Uniform nuclei with small nucleoli" "Monomorphic nuclei with inconspicuous nucleoli" "Round nuclei with multiple nucleoli" "Pleomorphic nuclei with prominent nucleoli" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4206.jpg" -"4207" "In the portion of the image that exhibits connective tissue, what is the primary cell type seen among the blood vessels?" "Neutrophils" "Fibroblasts" "Lymphocytes" "Eosinophils" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4207.jpg" -"4208" "Based on the cellular morphology and distribution pattern, what type of cellular proliferation does this image most likely represent?" "Melanocytic proliferation" "Sarcomatoid differentiation" "Granulomatous reaction" "Inflammatory infiltrate" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4208.jpg" -"4209" "What does the presence of regular structures resembling blood vessels within the tissue suggest?" "Normal vascular architecture" "Abnormal angiogenic activity" "Poorly formed granulation tissue" "Necrosis within the tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4209.jpg" -"4210" "Regarding the staining pattern observed, which protein is the staining most suggestive of?" "HMB45, a marker for melanocytic cells" "CD20, a marker for B lymphocytes" "CD3, a marker for T lymphocytes" "AE1/AE3, a broad-spectrum cytokeratin marker" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4210.jpg" -"4211" "Which pattern of cell clustering does NOT align with the observations in this tissue section?" "Tightly packed nests of epithelioid cells with scant matrix" "Cells clustered together reminiscent of benign chondrocytes" "Cells in a linear arrangement parallel to the matrix fibers" "Stellate or fusiform cells with less structured intercellular material" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4211.jpg" -"4212" "What cellular morphology can predominantly be observed dispersed throughout this tissue section?" "Uniformly small lymphocyte-like cells" "Chondrocyte-like cells with round to oval nuclei" "Predominantly spindle cells with high mitotic activity" "Primarily large, multinucleated cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4212.jpg" -"4213" "What is the cytoplasmic characteristic of the lesion illustrated in this image?" "The cells possess an abundant amount of cytoplasm" "The cytoplasm has a foamy appearance" "The cells have scarce cytoplasm" "The cells display a clear perinuclear halo" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4213.jpg" -"4214" "In terms of cellular morphology, how would you describe the appearance of the nuclei within the spindle cells?" "Hyperchromatic and pleomorphic nuclei" "Small, hyperchromatic nuclei" "Irregular, elongated nuclei" "Round, uniform nuclei with prominent nucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4214.jpg" -"4215" "How do the air spaces, or alveoli, appear in the image?" "Filled with granulomatous inflammation" "Containing abundant foamy macrophages" "Clear but compromised by pneumocyte detachment" "Collapsed and fibrotic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4215.jpg" -"4216" "Based on the morphology of the skin section, what type of cell proliferation is visible in the epidermal basal layer?" "Keratinocytic hypopigmentation" "Fibroblastic proliferation" "Lymphocytic infiltration" "Melanocytic hyperpigmentation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4216.jpg" -"4217" "What is the shape of the cells found in the most superficial layer of this transitional epithelium?" "Columnar" "Squamous" "Dome-shaped" "Cuboidal" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4217.jpg" -"4218" "Considering the staining technique used in this tissue, what are the darker areas most likely representing?" "Regions of calcification within the tissue" "Areas of increased cellularity in the neoplasm" "Spaces filled with mucinous material" "Blood vessels and stromal components" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4218.jpg" -"4219" "What characteristic of the nuclei in the epithelial cells is notable in this microscopic image?" "Uniform nuclear size and shape" "All nuclei are evenly spaced" "Nuclei do not occupy a significant portion of each cell" "Increased nuclear to cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4219.jpg" -"4220" "In the stroma surrounding the glandular structures in the image, what can be observed?" "Dense fibrotic tissue indicative of a significant desmoplastic reaction" "Scant stromal tissue with no signs of a desmoplastic reaction" "Extensive necrosis and inflammatory infiltrate throughout the stroma" "High vascular density with numerous blood vessel formations" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4220.jpg" -"4221" "How are the granulosa cells organized around the oocyte?" "As a loosely arranged connective tissue" "As a single row of columnar cells" "As multiple concentric layers of spindle-shaped cells" "As a layer of closely packed cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4221.jpg" -"4222" "The blood vessels scattered throughout the sample display a particular feature. Which statement best describes the blood vessel walls seen in this sample?" "They exhibit extensive perivascular inflammation." "They are predominantly collapsed with no visible lumen." "They have prominent walls." "They have thin, inconspicuous walls." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4222.jpg" -"4223" "Examination of the stromal component within the tissue shows a particular change. What is the nature of the stromal change observed?" "Ossification" "Fibrinoid necrosis" "Hyalinization" "Myxoid change" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4223.jpg" -"4224" "What is the shape of the cells observed in the provided tissue section?" "Cuboidal" "Columnar" "Transitional" "Squamous" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4224.jpg" -"4225" "How are the nuclei positioned in the epithelial cells displayed in this image?" "Eccentrically towards one side" "Centrally within each cell" "At the apical surface" "Basally near the underlying basement membrane" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4225.jpg" -"4226" "What is the predominant type of cells found on the periphery of the stratified structures?" "Spindle-shaped cells with dense nuclei" "Columnar cells with nuclei aligned perpendicular to the base" "Cells with abundant cytoplasm and vesicular nuclei" "Small cells with round, dense nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4226.jpg" -"4227" "The darker staining cells interspersed among the columnar cells of the stratified structures are likely involved in which function?" "Immunological defense" "Sensory function" "Structural support" "Secretory activity" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4227.jpg" -"4228" "Assessing the tissue architecture in the image, which of the following patterns best describes the arrangement of the cells?" "Palisading arrangement" "Glandular formation" "Rosette formation" "Storiform pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4228.jpg" -"4229" "What pattern of melanocytic proliferation is evident at the basal layer?" "Uniform distribution without increase in number" "Formation of well-defined nests" "Lentiginous distribution with increased number" "Pagetoid spread throughout the epidermis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4229.jpg" -"4230" "What is the predominate cell shape observed in the microscopic view of the tissue?" "Irregularly shaped" "Round-to-oval" "Spindle-shaped" "Flattened" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4230.jpg" -"4231" "Regarding the nuclei of the cells in the image, which of the following best describes their appearance?" "Round and relatively uniform" "Vesicular with prominent nucleoli" "Crushed or smudged" "Hyperchromatic and pleomorphic" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4231.jpg" -"4232" "What type of inflammatory cells predominate around the crystal deposits?" "Mononuclear cells" "Multinucleated giant cells" "Eosinophils" "Neutrophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4232.jpg" -"4233" "Based on the cellular morphology visible in the tissue, which characteristic is less prominent?" "Myxoid matrix" "Necrosis" "Lipoblastic differentiation" "Pleomorphism" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4233.jpg" -"4234" "Based on the nuclear features observed in the cells, what is the most likely characterization of their nuclei?" "Scalloped due to the cytoplasmic vacuolation" "Hypersegmented with basophilic stippling" "Large with multiple prominent nucleoli" "Multilobated with neutrophilic stippling" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4234.jpg" -"4235" "How would you describe the cellular population's uniformity based on the image?" "Uniformly hyperchromatic nuclei throughout" "Syncytial arrangement without distinct cellular borders" "Monomorphic cells with uniform nuclei" "High degree of pleomorphism" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4235.jpg" -"4236" "Based on the histological appearance, what is the primary function of the cells indicated by 'B' within the thyroid gland?" "Production of calcitonin" "Phagocytosis and antigen presentation" "Production of insulin and glucagon" "Production of thyroxine and triiodothyronine" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4236.jpg" -"4237" "What morphological features differentiate the cell labeled 'B' from the cells labeled 'A' in the thyroid gland?" "Cell 'B' has a clearer cytoplasm and is larger than cell 'A'" "Cell 'B' is smaller and has a high nucleus-to-cytoplasm ratio" "Cell 'B' contains a centrally located nucleus and is cuboidal in shape" "Cell 'B' has a more eosinophilic cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4237.jpg" -"4238" "Based on the cells' nuclear features, which of the following best describes the tissue in this image?" "Monomorphic nuclei" "Anisokaryosis" "Hyperchromasia" "Macronucleoli" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4238.jpg" -"4239" "Judging by the cellular arrangement and the presence of a lumen, what is the most likely functional feature of the marked structure?" "Secretion of enzymes" "Structural support" "Gas exchange" "Filtration of blood plasma" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4239.jpg" -"4240" "What is the cellular morphology of the majority of cells surrounding the marked lumen?" "Cells with abundant clear cytoplasm and small, dark nuclei" "Spindle-shaped cells with elongated nuclei" "Flat cells with squamous nuclei" "Cells with pyramidal shape and round nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4240.jpg" -"4241" "Based on the appearance of the epidermis in this H&E stained skin tissue, which of the following best describes its condition?" "Marked acanthosis with elongated rete ridges" "Hyperkeratosis with a thickened stratum corneum" "Atrophic changes with a thinned epidermis" "Psoriasiform hyperplasia with uniform epidermal thickening" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4241.jpg" -"4242" "In the histopathological image shown, what is the nature of the cellular infiltration seen predominantly within the dermis?" "Neutrophilic infiltrate associated with acute inflammation" "Lymphocytic infiltrate suggesting a chronic inflammatory response" "Eosinophilic infiltrate typical of parasitic infections" "Granulomatous infiltration indicative of granulomatous diseases" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4242.jpg" -"4243" "What stage of development does the central structure in the image most likely represent?" "Secondary oocyte within a corpus luteum" "Secondary oocyte within a Graafian follicle" "Primary oocyte within a primordial follicle" "Primary oocyte within a primary follicle" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4243.jpg" -"4244" "Identify the tissue type that makes up the dense outermost layer observed in the image?" "Ovarian medulla" "Theca externa" "Ovarian cortex" "Ovarian stroma" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4244.jpg" -"4245" "Based on the morphology displayed in the image, which cellular layer immediately surrounds the central cell?" "The cumulus oophorus" "The layer of theca interna cells" "The layer of granulosa cells" "The zona pellucida" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4245.jpg" -"4246" "Based on the morphology, what is the most likely function of the tissue depicted in this image?" "Absorption and secretion" "Sensory reception" "Structural support" "Thermoregulation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4246.jpg" -"4247" "What type of epithelial cell lining arrangement can be observed within the tubular structures in this microscopic image?" "Simple columnar epithelium" "Stratified columnar epithelium" "Transitional epithelium" "Simple cuboidal epithelium" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4247.jpg" -"4248" "Which structures are surrounded by dense irregular connective tissue in this image?" "Nerve fibers" "Blood vessels" "Glandular ducts" "Muscle fibers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4248.jpg" -"4249" "What does the tissue architecture of the mass indicate about its potential behavior?" "Highly aggressive due to the disorganized structure" "Likely benign due to uniform cells and well-circumscribed margins" "Likely malignant due to cellular pleomorphism" "Inconclusive without further genetic testing" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4249.jpg" -"4250" "Based on the histological features present in this tissue section, what is the most likely cellular morphology observed?" "Spindle-shaped cells with abundant cytoplasm" "Small round cells with minimal cytoplasm" "Uniform cells with a low nuclear-to-cytoplasmic ratio" "Pleomorphic cells with a high nuclear-to-cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4250.jpg" -"4251" "Based on the microscopic features observed, which cellular characteristic in the image is indicative of immature precursor cells within the sebaceous population?" "Larger cells with abundant clear cytoplasm" "Cells displaying darker-stained, smaller cytoplasm" "Cells with a uniform, light-staining cytoplasm and prominent nuclei" "The presence of multicellular layers indicating stratification" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4251.jpg" -"4252" "Based on the tissue morphology, what is the predominant cell shape within the nodular formations?" "Spindle-shaped" "Columnar" "Cuboidal" "Round to oval" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4252.jpg" -"4253" "Based on the cellular features observed in the image, what type of tissue organization does this represent?" "Uniform cell distribution without clear boundaries" "Dense irregular connective tissue with inconsistent fiber arrangement" "Stratified epithelium with distinct layering" "Dense cellular area transitioning to less cellular matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4253.jpg" -"4254" "What is the predominant cytoplasmic characteristic of the cells in this histopathological image?" "Majority of the cells show a clear cytoplasm" "The cytoplasm in most cells appears highly vacuolated" "Most cells exhibit a basophilic cytoplasm" "Cells predominantly display a granular cytoplasm" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4254.jpg" -"4255" "Does the histopathological image suggest a well-organized tissue architecture?" "The tissue shows an organized glandular pattern" "Tissue arrangement indicates a highly regular, fibrous structure" "The image displays disorganized tissue architecture" "There is an identifiable squamous cell layered structure" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4255.jpg" -"4256" "Within the dermis of this skin sample, what does the eosinophilic material suggest?" "Inflammatory infiltration" "Elastosis due to sun exposure" "Melanin accumulation" "Normal distribution of collagen fibers" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4256.jpg" -"4257" "Based on the observed tissue architecture, which feature is most consistent with glandular differentiation?" "Regularly spaced, circular glandular structures" "Irregularly shaped gland-like formations" "Uniform cell size and shape throughout the tissue" "Lack of stromal component around cellular structures" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4257.jpg" -"4258" "Based on the cell morphology observed in the epithelial layer, what is the most likely characteristic of the nuclei?" "The nuclei are predominantly small and uniform, suggesting mature differentiation" "The nuclei exhibit a uniform size with little variation" "The nuclei demonstrate anisokaryosis with marked size variation" "The nuclei show multi-nucleation in most epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4258.jpg" -"4259" "What characteristic of the cells infiltrating the gastric mucosa suggests an active pathological process in the observed tissue?" "Their high density within the lamina propria" "Increased mitotic figures" "The presence of signet ring cells" "The hyperplastic nature of the gastric mucosa" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4259.jpg" -"4260" "Based on the morphological features observed in the gastric mucosal tissue, what type of inflammatory cells are predominantly infiltrating the lamina propria?" "Lymphocytes" "Basophils" "Neutrophils" "Eosinophils" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4260.jpg" -"4261" "In the provided image of gastric mucosal tissue, the epithelial compartment is observed to be infiltrated by which type of cell?" "Eosinophils" "Fibroblasts" "Mast cells" "Macrophages" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4261.jpg" -"4262" "Which characteristic feature of the epithelium is evident in this image?" "Keratinized surface" "Stratified squamous morphology" "Presence of goblet cells" "Ciliated columnar cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4262.jpg" -"4263" "Within the connective tissue stroma beneath the epithelium, what can be observed?" "Chondrocytes in lacunae" "Diffuse infiltration of uniform cells" "Dense regular connective tissue" "Adipose tissue deposits" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4263.jpg" -"4264" "How would you describe the appearance of the nuclei in this specimen?" "The nuclei are hyperchromatic and larger than normal" "The nuclei display a clear nucleoli in every cell" "The nuclei are small and pyknotic" "The nuclei have a uniform condensation of chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4264.jpg" -"4265" "Which of the following best characterizes the presence of inflammatory cells in this tissue section?" "Inflammatory cells are highly concentrated in the epithelium" "Inflammatory cells are scattered within the lamina propria" "Inflammatory cells are present throughout the lamina propria" "Inflammatory cells are absent from the lamina propria" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4265.jpg" -"4266" "Which description best matches the appearance of the chromatin within the nuclei of the abnormal cells in this image?" "Vesicular chromatin with prominent nucleoli" "Condensed chromatin with large, central nucleoli" "Homogenous chromatin with small and indistinct nucleoli" "Hyperchromatic and smudged chromatin with no nucleoli" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4266.jpg" -"4267" "Based on the cellular morphology observed, which cells are indicative of a chronic inflammatory process in this tissue?" "Multinucleated giant cells with abundant eosinophilic cytoplasm" "Erythrocytes within vascular channels" "Small lymphocytes with scant cytoplasm" "Neutrophils with multi-lobed nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4267.jpg" -"4268" "What does the chromatin pattern of the cells in this high-power field microscopy image suggest?" "The chromatin is evenly distributed and indicates healthy cellular replication." "The chromatin pattern is hyperchromatic and indicates increased proliferation." "The chromatin pattern is irregular and suggests malignancy." "The chromatin is condensed uniformly, suggesting apoptotic activity." "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4268.jpg" -"4269" "What can be inferred about the cellular turnover in the tissue presented in this microscopy image?" "There is evidence of low cellular turnover due to the absence of mitotic figures." "The presence of prominent nucleoli suggests high cellular turnover and active replication." "Multi-nucleated cells indicate low cellular turnover and arrested growth." "Uniform cell size points to highly regulated and normal cellular turnover." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4269.jpg" -"4270" "What is the characteristic of the nuclei in the epithelial cells lining the glands?" "Pleomorphism with variation in size and shape" "Small size with inconspicuous nucleoli" "Presence of multiple nuclei within a single cell" "Uniformity in size and shape" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4270.jpg" -"4271" "What does the red-staining material inside some of the luminal structures most likely represent?" "Collagen fibers" "Secretory products" "Erythrocytes" "Inflammatory cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4271.jpg" -"4272" "Based on the histological features present in the image, what is the most likely tissue origin of the sample?" "Dense irregular connective tissue" "Cardiac muscle tissue" "Simple glandular epithelium" "Stratified squamous epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4272.jpg" -"4273" "What type of epithelium is lining the cystic structure observed in the microscopic image?" "Simple squamous epithelium" "Stratified squamous epithelium" "Simple columnar epithelium" "Pseudostratified columnar epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4273.jpg" -"4274" "Based on the microscopic features of the cystic structure, what additional feature supports the diagnosis of an infundibular cyst?" "Presence of cilia" "Lack of a granular layer" "Presence of a granular layer" "Multinucleated giant cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4274.jpg" -"4275" "Within the cystic space, what type of material can be primarily observed?" "Mucoid substance" "Serous fluid" "Loose keratin debris" "Haemorrhagic fluid" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4275.jpg" -"4276" "In the given microscopic view, the appearance of the luminal spaces of the glands can best be described as:" "Irregularly distended containing cellular debris or secretions" "Regularly distended with prominent secretions" "Uniformly collapsed without evidence of secretions" "Regularly distended with uniform cellular lining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4276.jpg" -"4277" "Based on the staining pattern, what does the cytoplasm of the cells in the duct-like structure in the image most likely indicate about their function?" "Lipid storage due to vacuolation" "Secretion of a substance due to the pale acidophilic character" "Phagocytic activity due to the presence of many lysosomes" "Protein synthesis and secretion due to rough endoplasmic reticulum presence" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4277.jpg" -"4278" "What feature of the epithelial structures seen in this tissue section can help differentiate between benign epithelial formations and potential malignancy?" "Variation in nuclear size and shape" "Uniformity in nuclear size and shape" "Lack of clear luminal spaces" "Loss of basal cell layer integrity" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4278.jpg" -"4279" "Which layer of the skin is predominantly thickened in the tissue sections shown in the image?" "Stratum basale" "Stratum corneum" "Stratum granulosum" "Stratum spinosum" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4279.jpg" -"4280" "What does the presence of clear spaces surrounding Civatte bodies in the epidermis indicate?" "Vacuolar alteration" "Basal cell hyperplasia" "Dermal edema" "Spongiosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4280.jpg" -"4281" "Based on the observed cellular morphology, which description best characterizes the nuclei's orientation within the cells?" "Randomly scattered nuclei with high nuclear-to-cytoplasmic ratio" "Centrally located nuclei with abundant cytoplasm" "Basally-oriented nuclei with eosinophilic cytoplasm" "Apically-oriented nuclei with clear cytoplasm" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4281.jpg" -"4282" "Assessing the tissue sample, what can be said about the presence of mitotic figures?" "Abnormal or atypical mitotic figures suggesting dysplasia" "Absence of mitotic figures suggesting lack of active cell division" "Occasional typical mitotic figures consistent with normal regeneration" "Numerous mitotic figures indicative of high cell turnover" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4282.jpg" -"4283" "What do the irregular spaces and clearings in the tissue likely represent?" "Artifacts from tissue processing" "Accumulations of fatty material" "Areas of recanalization within the thrombus" "Regions of necrosis and apoptosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4283.jpg" -"4284" "What is the appearance of the cytoplasm in small lymphocytes observed in this cytology smear?" "Abundant with granules" "Sparse and pale" "Dense and deeply basophilic" "Vacuolated and frothy" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4284.jpg" -"4285" "In the cytology smear, which type of cells are characterized by a 'cartwheel' appearance of the nucleus?" "Larger reactive lymphoid cells" "Small lymphocytes with sparse cytoplasm" "Cells with a clear halo around the nucleus" "Plasma cells with dark blue cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4285.jpg" -"4286" "Based on the observation of the nuclear features, what is the predominance of the chromatin pattern?" "Uniformly dense without nucleoli" "Heterogenous with visible nucleoli" "Coarse and clumped" "Homogeneous and finely dispersed" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4286.jpg" -"4287" "In the stromal matrix, what is the appearance of the collagen fibers?" "Abundant with continuous thick bands" "Distributed uniformly surrounding the individual cells" "Absent with no pink-staining areas" "Sparse, appearing as occasional pink-staining areas between cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4287.jpg" -"4288" "Based on the image, which of the following best describes the appearance of the nuclei within the glandular structures?" "Large, hyperchromatic, and pleomorphic nuclei" "Round nuclei with prominent nucleoli and abundant cytoplasm" "Small, hyperchromatic nuclei with scant cytoplasm" "Uniform in size and shape with finely dispersed chromatin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4288.jpg" -"4289" "How would you characterize the nuclei of the smaller cells in the image?" "Hypochromatic and regular" "Uniform in size with prominent nucleoli" "Shows evidence of karyorrhexis" "Hyperchromatic and atypical" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4289.jpg" -"4290" "What can be deduced about the nature of the pink-stained material in the upper part of the image?" "It suggests a myxoid matrix." "It is consistent with fibrous tissue." "It is indicative of a necrotic process." "It indicates a deposition of adipose tissue." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4290.jpg" -"4291" "The small, round to oval structures within the cellular region surrounded by cells with high nucleus-to-cytoplasm ratios are likely to be what anatomical structure based on their morphology?" "Sweat glands" "Follicular structures" "Muscle fibers" "Blood vessels" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4291.jpg" -"4292" "Based on the morphology observed in this image, which architectural pattern is NOT evident in the specimen?" "Interlacing fascicles of spindle-shaped cells" "Rounded structures reminiscent of vessel formation" "Large areas of necrosis surrounded by palisading tumor cells" "Vascular channels lined by endothelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4292.jpg" -"4293" "What is the morphology of the background extracellular substance observed in the image?" "Cellular with inflammatory infiltrate" "Fibrillar with distinct fibers" "Homogenous with a glassy appearance" "Granular with microcalcifications" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4293.jpg" -"4294" "Based on the observed histological features, how would you characterize the central lesion?" "An abscess with a collection of pus" "A necrotizing granuloma with central cell death" "A non-necrotizing granuloma without overt necrosis" "A cystic structure with fluid-filled cavity" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4294.jpg" -"4295" "What is the predominant type of bone tissue observed in this image?" "Trabecular bone with interconnected lattice structure" "Cortical bone with dense, solid structure" "Lamellar bone with organized, concentric lamellae" "Woven bone with disorganized collagen strands" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4295.jpg" -"4296" "Based on the microscopic features, what type of changes are observable in the cyst-like spaces within the tissue?" "Blood-filled spaces indicative of cystic changes" "Accumulation of adipocytes forming lipoid structures" "Mucinous deposits within well-defined glandular spaces" "Keratin pearls within well-differentiated squamous cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4296.jpg" -"4297" "What can be inferred about the nuclear to cytoplasmic ratio in the cells visible in this photomicrograph?" "The nuclear to cytoplasmic ratio is not discernible" "Most cells demonstrate a low nuclear to cytoplasmic ratio" "Most cells exhibit an equal nuclear to cytoplasmic ratio" "Most cells show a high nuclear to cytoplasmic ratio" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4297.jpg" -"4298" "Assessing the cell morphology, what can be deduced about the level of pleomorphism in this tissue sample?" "Moderate pleomorphism with some noticeable variation in cell size and shape" "Uniform pleomorphism throughout the tissue" "Low pleomorphism with minimal variation in cell size and shape" "High degree of pleomorphism with significant variation in cell size and shape" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4298.jpg" -"4299" "Considering the appearance of the most superficial cells, how can we describe the state of keratinization in this tissue?" "Hyperkeratinized, with a significant thickening of the dead cell layer" "Non-keratinized, as there is no layer of dead cells without nuclei" "Parakeratinized, with partially visible nuclei in the superficial cells" "Fully keratinized, with a distinct layer of dead cells without nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4299.jpg" -"4300" "Based on the nuclear staining seen in the image, what can be inferred about the lymphocytes present in the tissue?" "They are predominantly necrotic" "They are reactive to an immunohistochemical stain" "They are undergoing apoptosis" "They exhibit significant cellular atypia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4300.jpg" -"4301" "What microscopic feature suggests the presence of fat necrosis within the observed adipose tissue?" "Uniformly stained adipocytes" "Presence of giant cells" "Clear spaces between adipocytes" "Pinkish material within adipose lobules" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4301.jpg" -"4302" "What is the characteristic feature of the surrounding stroma in this section of skin?" "Slightly fibrous connective tissue" "Highly vascularized tissue" "Dense acute inflammatory infiltrate" "Presence of adipose tissue" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4302.jpg" -"4303" "What histological feature differentiates the stroma surrounding the glandular structures in this image?" "A lack of connective tissue fibers and a homogeneous appearance" "Hypercellularity with a chaotic arrangement" "Dense clusters of inflammatory cells" "Presence of a pink-staining matrix with scattered cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4303.jpg" -"4304" "Based on the morphology of the epithelial cells lining the projections, how would you best describe the nuclei's location?" "Apically located nuclei" "Basally located nuclei" "Centrally located nuclei" "Randomly scattered nuclei throughout the cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4304.jpg" -"4305" "Regarding the stroma between the projections, select the characteristic that is least congruent with the observed morphology in the image." "Highly cellular stroma" "Dense extracellular matrix components" "Sparsely populated stroma" "Predominantly acellular areas" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4305.jpg" -"4306" "Based on the microscopic features present in this lung tissue section, which of the following conditions is most likely represented?" "Pulmonary tuberculosis" "Chronic interstitial pneumonitis" "Lobar pneumonia" "Acute bronchopneumonia" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4306.jpg" -"4307" "Based on the tissue architecture, what is the arrangement pattern of spindle-shaped cells in the observed histologic image?" "Storiform pattern" "Haphazard distribution" "Alveolar pattern" "Palisading arrangement" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4307.jpg" -"4308" "What type of material is scattered throughout the tissue in the histologic image?" "Necrotic debris" "Mucinous stroma" "Ossified matrix" "Dense collagen" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4308.jpg" -"4309" "Based on the morphology of the most abundant cell type in this liver tissue section, which of the following features is predominantly observed in the cytoplasm?" "Large, eosinophilic granular appearance" "Dark blue/black pigment accumulation" "Small vacuoles indicative of lipid droplets" "Sparse cytoplasm with high nucleus-to-cytoplasm ratio" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4309.jpg" -"4310" "In the histological analysis of this liver tissue, where do we see the exchange of substances between the blood and liver cells occurring?" "At the Space of Disse" "Across the hepatocyte cellular membranes visibly outlined" "Within the central vein" "Inside the Sinusoidal spaces" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4310.jpg" -"4311" "In the given cross-sectional image of the tubular structure, which histological layer is directly adjacent to the lumen?" "Submucosa" "Muscularis externa" "Mucosa" "Intima" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4311.jpg" -"4312" "Based on the immunohistochemical staining observed in the image, which area shows the highest Ki-67 expression indicative of cell proliferation?" "The areas within the epidermis" "The stratum corneum" "The dermal connective tissue" "The lobules of nevus cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4312.jpg" -"4313" "Based on the histological appearance, which structure in the image is associated with the hair follicles in their normal anatomical relationship?" "Large lobular structures with vacuolated cells" "Palisading layers of follicular cells" "Dilated blood vessels containing red blood cells" "Scattered fibroblast cells within collagen fibers" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4313.jpg" -"4314" "Based on the morphological characteristics, what type of cell predominates the tissue section?" "Lymphocytes" "Neutrophils" "Eosinophils" "Plasma cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4314.jpg" -"4315" "Identify the nuclear change evident in the cellular infiltrate indicative of cell death or pathology." "Pyknosis" "Anaplasia" "Karyolysis" "Karyorrhexis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4315.jpg" -"4316" "Based on the absence of certain structures, which area of the body does this tissue sample most likely represent?" "Abdomen" "Palm of the hand" "Vermilion border of the lip" "Scalp" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4316.jpg" -"4317" "What is the predominant stromal characteristic in the histological section?" "Highly cellular with prominent vasculature" "Pinkish hue suggesting collagen deposition" "Dense with a hyaline quality" "Loosely arranged with abundant myxoid substance" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4317.jpg" -"4318" "Assessing the nuclear features, what can be inferred about the cells in this tissue section?" "The nuclei are hyperchromatic with severe atypia" "The nuclei appear round to ovoid with some variation in size and shape" "The nuclei show significant pleomorphism and numerous mitotic figures" "The nuclei are smudged and indistinct, suggesting high-grade malignancy" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4318.jpg" -"4319" "Which cellular feature is common among the cells lining the seminiferous tubules that suggests their role in supporting and nurturing developing sperm cells?" "Cytoplasmic extensions" "Large, irregular nuclei" "Large, round nuclei" "Multiple small nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4319.jpg" -"4320" "Which of the following characteristics is consistent with the cells in this image?" "Presence of stroma interspersed between the cell clusters" "Multinucleated giant cells" "Nuclei with a high degree of pleomorphism" "Cells exhibiting a uniform cytoplasmic staining" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4320.jpg" -"4321" "Based on the staining pattern and cellular morphology, what type of tissue might this be indicative of?" "Skeletal muscle tissue" "Neuroendocrine tissue" "Hepatic tissue" "Adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4321.jpg" -"4322" "Assessing the cytoplasmic characteristics, which description is consistent with the cells in the image?" "Abundant clear, vacuolated cytoplasm" "Moderate amount of eosinophilic cytoplasm" "Scanty cytoplasm giving a 'fried-egg' appearance" "Abundant and deeply eosinophilic cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4322.jpg" -"4323" "What feature is indicated by the red arrows in the provided histological image of cartilage tissue?" "The territorial matrix" "The isogenous group" "The perichondrium" "The interterritorial matrix" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4323.jpg" -"4324" "Considering the presence of nuclear characteristics in this tissue, which of these observations about the nuclei is accurate?" "Enlarged, bizarre-shaped nuclei without visible cytoplasmic inclusion" "Most nuclei show a uniform color with clear nucleoli" "Nuclei mostly have a regular shape and size without any visible atypia" "Multiple cells with enlarged, bizarre-shaped nuclei including some with nuclear pseudo-inclusions" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4324.jpg" -"4325" "What alteration in the granular layer (stratum granulosum) is evident in this histological section?" "Atrophy of the granular layer" "Hyperpigmentation of the granular layer" "Lack of keratohyalin granules in the granular layer" "Thickening of the granular layer" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4325.jpg" -"4326" "What is the predominant staining characteristic of the cytoplasm of the cells seen in this microscopic image?" "Basophilic (blue)" "Amphophilic (purple)" "Acidophilic (pink)" "Neutrophilic (neutral)" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4326.jpg" -"4327" "What feature of the surrounding stroma can be observed in this microscopic view?" "Loose connective tissue with abundant ground substance" "Abundance of adipose tissue" "Presence of dense irregular connective tissue with interspersed spindle-shaped fibroblasts" "Marked inflammatory infiltrate" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4327.jpg" -"4328" "What is the morphological feature of the red blood cells (RBCs) visible in this peripheral blood smear?" "Rouleaux formation" "Poikilocytosis" "Anisocytosis" "Agglutination" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4328.jpg" -"4329" "Identify the pattern exhibited by some cell clusters in the tissue that might suggest a specific type of benign growth." "Syncytial pattern" "Alveolar pattern" "Rosette pattern" "Whorled pattern" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4329.jpg" -"4330" "What can be inferred about the cytoplasmic staining of the cells in these gland-like structures?" "The cytoplasm exhibits basophilic staining with a dark blue appearance." "The cytoplasm demonstrates an eosinophilic staining with a bright pink appearance." "The cells present clear cytoplasm suggesting high glycogen content." "The cytoplasm displays a mucinous consistency with a light pink, translucent staining." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4330.jpg" -"4331" "Based on the striation pattern observed, which type of muscle tissue is represented in this image?" "Smooth muscle" "Cardiac muscle" "Skeletal muscle" "No specific type can be determined" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4331.jpg" -"4332" "Based on the microscopic appearance, what pigment is likely present within the cytoplasm of these cells?" "Melanin" "Hemoglobin" "Hemosiderin" "Lipofuscin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4332.jpg" -"4333" "Based on the cellular morphology observed, what is the predominant cell shape in this tissue sample?" "Polygonal with abundant cytoplasm" "Cuboidal and forming duct-like structures" "Round and closely packed" "Spindle-shaped with elongated nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4333.jpg" -"4334" "What tissue characteristic can be inferred from the organization of the cells within the extracellular matrix?" "Palisading pattern around necrotic areas" "Streaming and intersecting pattern of growth" "Disorganized growth pattern without a specific structural arrangement" "Formation of acinar structures typical of glandular epithelium" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4334.jpg" -"4335" "Based on the cellular structure and coloration, what type of tissue occupies the lower region of the image?" "Muscle tissue" "Fibrous connective tissue" "Bone tissue" "Neural tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4335.jpg" -"4336" "Based on the infiltration observed in the image, which type of cells predominantly make up the inflammatory cell infiltrate within the lamina propria?" "Eosinophils" "Macrophages" "Neutrophils" "Plasma cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4336.jpg" -"4337" "The nodules present in the central and right regions of the image with dense, eosinophilic cytoplasm and variable nuclear size are indicative of what type of pathological process?" "Fibrotic scarring" "Acute bacterial infection" "Neoplastic transformation" "Chronic inflammation with granulomatous features" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4337.jpg" -"4338" "What type of connective tissue predominates in the described microscopic image?" "Reticular connective tissue" "Loose connective tissue" "Adipose tissue" "Regular connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4338.jpg" -"4339" "What feature is observed in some of the nuclei that suggests active cellular processes such as engulfment?" "Large central nucleoli within the nuclei" "Nuclei with a singular, compact structure" "Engulfment by multinucleated giant cells" "Nuclei with uniform size and shape" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4339.jpg" -"4340" "Identify the type of cells predominantly seen within the blister cavity in the provided skin tissue section." "Eosinophils" "Lymphocytes" "Neutrophils" "Basophils" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4340.jpg" -"4341" "How would you describe the appearance of the nuclei in these cells?" "The nuclei are elongated and wavy in contour." "The nuclei are hypersegmented and exhibit a clover-leaf shape." "The nuclei are small, dark, and show multiple nucleoli." "The nuclei are large and round with a smooth contour." "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4341.jpg" -"4342" "Based on the observed tissue characteristics, what type of epithelium is present at the top portion of the image?" "Simple squamous epithelium" "Simple columnar epithelium" "Stratified squamous epithelium" "Pseudostratified columnar epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4342.jpg" -"4343" "Based on the immunohistochemical staining, which antigen is positively marked in the spindle cells within the tissue?" "Desmin" "S-100" "CD68" "CD34" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4343.jpg" -"4344" "What feature is absent in this microscopic view of the tissue that would suggest an aggressive or malignant process?" "Necrosis" "Mitotic figures" "Lipoblasts" "Inflammatory infiltrate" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4344.jpg" -"4345" "Assessing the degree of maturation in the epidermal layer, what observation can be made?" "Maturation is normal, with a clear progression from basal to stratum corneum" "There is a lack of maturation with disorganization in the epidermal stratification" "Cells display maturation arrest at the granular layer with normal basal and spinous layers" "Maturation is increased, with cells becoming flattened and losing their nuclei as they move upward" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4345.jpg" -"4346" "What is the orientation of the nuclei within the columnar epithelial cells observed in the gastric pits of this gastric mucosa section?" "Randomly scattered throughout the cell body" "Oriented towards the apical surface" "Oriented towards the base" "Uniformly distributed at the center of the cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4346.jpg" -"4347" "What type of cellular atypia is most apparent within the epithelial linings of the cysts in this tissue sample?" "Significant nuclear pleomorphism and hyperchromasia" "High mitotic activity and necrosis" "No evidence of cellular atypia" "Variation in nuclear size and mild stratification" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4347.jpg" -"4348" "What other tissue type can be identified in this histological image?" "Myxoid connective tissue with sparse fibroblasts" "Skeletal muscle tissue with cross striations" "Dense, fibrous connective tissue with stromal components" "Lymphatic tissue with prominent germinal centers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4348.jpg" -"4349" "Based on the image, what histological feature can be observed in the areas where the tissue appears lighter in color?" "Dense clusters of inflammatory cells" "Necrosis with loss of cellular detail and structure" "Presence of numerous blood vessels and vascular structures" "Extensive fibrosis and increased extracellular matrix" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4349.jpg" -"4350" "What is the primary characteristic of the extracellular matrix in this microscopic image?" "Large amounts of hyaluronic acid" "Abundance of collagen fibers" "Presence of elastin fibers" "Dense accumulations of melanin granules" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4350.jpg" -"4351" "Which morphological characteristic is NOT present in this image of basal cell carcinoma?" "Hyperkeratosis" "Thickened epidermis" "Elongated rete ridges" "Disorganized growth pattern in the dermis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4351.jpg" -"4352" "When observing the dermal component beneath the basaloid cell proliferation, which of these features is NOT observed?" "Presence of fibroblasts" "Increased mitotic activity" "Compressed collagen fibers" "Relatively normal arrangement of the dermis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4352.jpg" -"4353" "Observing the basal layer of the epidermis in the image, which description is more accurate?" "Disruption of the basal layer" "Presence of dyskeratotic cells" "Marked spongiosis" "Continuous line of darker-staining basal keratinocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4353.jpg" -"4354" "Based on cellular morphology, what is the most likely identity of the densely packed cells with darkly stained nuclei on the right side of the image?" "Adipocytes" "Hepatocytes" "Granule neurons" "Squamous epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4354.jpg" -"4355" "What is the predominant feature of this lung tissue section when examining the architecture?" "Variably-sized cystic spaces" "Alveolar consolidation" "Well-preserved airway structures" "Uniform alveolar distribution" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4355.jpg" -"4356" "What type of staining is prominently featured in the extracellular material of the tissue?" "Eosin" "Periodic acid-Schiff" "Masson's trichrome" "Hematoxylin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4356.jpg" -"4357" "Which cells in the image are indicative of a chronic inflammatory process?" "Cells with small, hyperchromatic nuclei and a scant cytoplasm" "Cells with small, dark-staining nuclei and scant cytoplasm" "Epithelial cells with large, pale nuclei" "Larger cells with abundant cytoplasm and a vesicular nucleus" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4357.jpg" -"4358" "Based on the morphology, what do the larger cells with abundant cytoplasm and vesicular nuclei, that appear to engage with the mucin, suggest?" "Fibroblasts during wound healing" "Lymphocytes involved in acute inflammation" "Histiocytes indicating phagocytic activity" "Neoplastic epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4358.jpg" -"4359" "Based on the image, what can be inferred about the stromal composition of this tissue sample?" "There is a clear presence of muscle fibers in a parallel arrangement" "The stroma appears to be densely fibrotic with abundant collagen" "The stroma contains pink-stained components like connective tissue intermingling with cellular elements" "There is a high level of adipocytes interspersed among the cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4359.jpg" -"4360" "What feature of the nuclei of the epithelial cells lining the glands is most apparent upon microscopic examination?" "Uniform nuclear size and shape" "Prominent nucleoli" "Multinucleated cells" "Variability in nuclear size and shape" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4360.jpg" -"4361" "What pattern of nuclei chromatin can be observed in the epithelial cells lining the glands?" "Nuclei with inconspicuous chromatin" "Euchromatic nuclei" "Hyperchromatic nuclei" "Hypochromatic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4361.jpg" -"4362" "What is the predominant cellular architecture observed in this microscopic image?" "Papillary structures with central fibrovascular cores" "Cohesive sheets of uniform cells" "Small, round blue cells forming rosettes" "Glandular formations with luminal necrosis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4362.jpg" -"4363" "What cytological feature suggests a high nuclear to cytoplasmic ratio in the cells within this image?" "Large cytoplasmic areas with small, inconspicuous nuclei" "Prominent nucleoli within large nuclei and abundant cytoplasm" "Small, round nuclei with scant cytoplasm" "Irregularly shaped and darkly stained nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4363.jpg" -"4364" "What type of specialized stroma can be identified in this image based on its staining characteristics?" "Fibrotic" "Myxoid" "Osseous" "Adipogenic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4364.jpg" -"4365" "What does the architecture of the glandular structures in this image suggest?" "Hyperplastic glands with increased stratification" "Atrophic glands with minimal cytoplasm" "Glands with a dilated and coiled pattern" "Uniform and regularly spaced glands" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4365.jpg" -"4366" "The eosinophilic staining of the cytoplasm observed in this image suggests an abundance of which proteins?" "Actin and myosin" "Keratin and vimentin" "Collagen and elastin" "Hemoglobin and myoglobin" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4366.jpg" -"4367" "What pattern best describes the arrangement of the spindle-shaped cells in this microscopic image?" "Storiform pattern" "Rosette pattern" "Palisading pattern" "Alveolar pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4367.jpg" -"4368" "Based on the cellular arrangement and morphology, which feature does NOT describe the vascular structures visibly scattered throughout this tissue section?" "Branching 'staghorn' vessels" "Hemangiopericytic vascular pattern" "Classic Kaposi sarcoma-like vascular spaces" "Prominent vascular proliferation" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4368.jpg" -"4369" "Considering the homogeneous appearance of the individual cells within this neoplastic tissue section, what finding is notably absent?" "Areas of necrosis" "All of the above" "Cellular pleomorphism" "Distribution of adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4369.jpg" -"4370" "Based on the coloration of the tissue surrounding the blue-stained structures, which staining technique is likely to have been used?" "Giemsa stain" "H&E (Hematoxylin and Eosin)" "Masson's Trichrome" "PAS (Periodic Acid-Schiff)" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4370.jpg" -"4371" "What characteristic feature is observed in the predominant cell population in this microscopic field?" "Multinucleated giant cell formations" "Intracellular bacteria phagocytosed" "Hyperchromatic and pleomorphic nuclei" "Bright blue cytoplasmic inclusions" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4371.jpg" -"4372" "Based on the orientation of nuclei, what type of muscle arrangement is illustrated at the periphery of the tissue in the image?" "Circular smooth muscle" "Longitudinal smooth muscle" "Skeletal muscle" "Obliquely arranged smooth muscle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4372.jpg" -"4373" "Considering the architecture of the skin lesion, what is the nature of the epidermal change observed in the image?" "Epidermal atrophy with basement membrane thickening" "Spongiosis with intercellular edema" "Acantholysis with suprabasilar clefting" "Hyperkeratosis with thickening of the stratum corneum" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4373.jpg" -"4374" "What does the presence of pink-stained homogeneous material throughout the connective tissue suggest?" "Extracellular deposition of amyloid protein" "Accumulation of collagen fibers" "Abundant cytoplasm in hypertrophic cells" "Dense aggregation of elastic fibers" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4374.jpg" -"4375" "What is the predominant cell shape observed in the high cellular density areas of the tissue section?" "Spindle-shaped" "Cuboidal" "Spherical" "Columnar" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4375.jpg" -"4376" "The presence of small, uniform red dots within the tissue suggests the possibility of which of the following?" "Coccobacilli" "Cellular debris" "Erythrocytes" "Apoptotic bodies" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4376.jpg" -"4377" "How would you describe the distribution of the antigen expression on the cell surfaces within these clusters?" "Varying levels of expression from cell to cell" "Negligible or absent expression" "Focal and patchy distribution" "Uniform expression across all cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4377.jpg" -"4378" "Looking at the structure in the bottom right of the image, what is the likely identity of this structure based on its morphological features?" "Sebaceous gland" "Nerve bundle" "Hair follicle" "Blood vessel" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4378.jpg" -"4379" "What feature is predominately observed in the stratified squamous epithelium of this tissue section?" "Cells with a high nuclear-to-cytoplasmic ratio" "Uniform cells with small, regular nuclei" "Abundant keratinization on the surface" "Cells organized in well-defined layers with proper maturation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4379.jpg" -"4380" "What is the characteristic staining pattern observed in the cytoplasm of the cells?" "Acidophilic, with a predominance of pink hues" "Amphophilic, with a mix of pink and blue hues" "Acidophilic, with a predominance of blue hues" "Basophilic, with a predominance of blue hues" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4380.jpg" -"4381" "Considering the organization of the cells within this tissue section, which description best fits?" "Cells display a disorganized, infiltrative growth pattern" "Cells are organized in well-defined lobular structures" "Cells form glandular structures with luminal spaces" "Cells are arranged in a pseudostratified layer" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4381.jpg" -"4382" "In the epithelial layer shown, what is the state of the superficial layers visualized at the top of the image?" "The superficial layers are thick and hyperkeratotic" "The superficial layers are eosinophilic and show signs of keratinization" "The superficial layers are thin and atrophic" "The superficial layers are highly vascularized and edematous" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4382.jpg" -"4383" "Based on the cellular morphology and staining pattern, this tissue could most likely represent which of the following?" "A non-neoplastic inflammatory process" "Normal healthy tissue" "A benign epithelial neoplasm" "A neoplasm of endothelial origin" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4383.jpg" -"4384" "Regarding the presence and distribution of the targeted antigen in the tissue, which of the following statements is accurate based on the image?" "The antigen is primarily expressed in the stromal elements." "The antigen is uniformly expressed in almost every cell." "The antigen is exclusively expressed in the non-stained areas." "The antigen is heterogeneously expressed throughout the tissue." "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4384.jpg" -"4385" "Based on the organization of the cells observed in the image, which structural feature is predominantly present?" "Solid nests of cells without lumina" "Dispersed single cells without a defined architecture" "Sheets of undifferentiated cells" "Organized structures suggestive of glandular or ductal differentiation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4385.jpg" -"4386" "Assessing the nuclear-cytoplasmic ratio, how do the nuclei present in relation to the size of the cytoplasm in the cells?" "The nuclei and cytoplasm are approximately the same size" "The nuclei are disproportionately enlarged compared to the cytoplasm" "The nuclei are large and take up most of the cell volume" "The nuclei are small relative to the abundant cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4386.jpg" -"4387" "What is the predominant cellular morphology observed in this tissue section?" "Squamous cells" "Multinucleated giant cells" "Round to oval cells" "Spindle-shaped cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4387.jpg" -"4388" "Considering the tissue architecture, how are the cells primarily organized within this section?" "Lined up in a pseudostratified manner" "Organized in clusters" "In a diffuse pattern" "Arranged in long fascicles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4388.jpg" -"4389" "In assessing the histological image for potential artifacts, what type of pigment accumulation is most consistent with what is observed in certain areas?" "Hemosiderin pigment, which is a golden yellow-brown color" "Melanin pigment, which appears as a dark brown to black color" "Lipofuscin pigment, which is a fine golden brown pigment granule" "Formalin pigment, which is dark brown and often accumulates in acidic environments" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4389.jpg" -"4390" "Based on the morphology of the nuclei observed, which statement best describes their appearance?" "The nuclei display a 'soap bubble' appearance, with multiple clearings within the nuclear envelope." "Nuclei are hyperchromatic with irregular borders, suggesting possible dysplasia or malignancy." "The nuclei appear pyknotic with condensed chromatin, indicative of necrosis or apoptosis." "Nuclei have prominent nucleoli and evenly distributed chromatin, consistent with active transcription and cell health." "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4390.jpg" -"4391" "In the given microscopic image of the artery, how does the boundary between the intima and the media layers appear?" "Obscured with smooth transition" "Reduplicated with multiple layers" "Accentuated with inflammatory infiltrates" "Distinct and well-delineated" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4391.jpg" -"4392" "Based on the image, which feature suggests cellular destruction and turnover?" "Separation of connective tissue fibers" "Darker staining fragments within the infiltrate" "Regular organization of the epithelium" "Pale pink amorphous material in the tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4392.jpg" -"4393" "Considering the presence of scattered inflammatory cells, what could this indicate about the tissue's condition?" "Chronic inflammatory response" "Immunological tissue tolerance" "Acute tissue injury" "Normal tissue homeostasis" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4393.jpg" -"4394" "In identifying the phase of the menstrual cycle for this endometrial sample, which characteristic is most notably absent?" "Single layer of columnar epithelial cells lining the glands" "Coiled spiral arteries" "Dense and cellular stroma" "Secretory activity within glandular lumens" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4394.jpg" -"4395" "Based on the histological features, what is the cytoplasmic staining characteristic of the cells present in the tissue?" "Amphiphilic" "Basophilic" "Eosinophilic" "Neutrophilic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4395.jpg" -"4396" "Observing the tissue structure and nuclear characteristics, which of the following cell features does not correlate with the observed histology?" "Eosinophilic cytoplasm" "Prominent nucleoli" "High-grade pleomorphism" "Mitotically active" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4396.jpg" -"4397" "Identify the structures within the dermis layer that resemble appendages such as sweat glands or hair follicles." "The densely packed, darker purple stained layers at the top of the tissue" "The clear separation between the uppermost layer and the underlying pink tissue" "The well-encapsulated round to oval shapes with a different staining pattern" "The irregular, pale structures scattered throughout the pink-staining tissue" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4397.jpg" -"4398" "What feature indicates the presence of neurons in this neural tissue section?" "Cells with a smaller, more densely stained nucleus and a perinuclear halo" "Cells with a dark-staining cytoplasm and no visible nucleus" "Cells with small, round nuclei and little cytoplasm" "Larger cells with a prominent nucleolus and visible nucleoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4398.jpg" -"4399" "What is the structural organization of the glands observed in the lower portion of this tissue section?" "Complex branching glands" "Simple coiled tubular glands" "Simple tubular glands" "Simple branched alveolar glands" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4399.jpg" -"4400" "How would you describe the organization of collagen fibers in the connective tissue observed in the image?" "Predominantly circular patterns" "Dense and irregularly arranged" "Regularly arranged parallel bundles" "Loose, randomly oriented" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4400.jpg" -"4401" "What does the granularity in the cytoplasm of the observed cells most likely represent?" "Lipofuscin pigment" "Calcific deposition" "Hemosiderin pigment" "Glycogen deposits" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4401.jpg" -"4402" "Which feature in this image supports the identification of well-differentiated cells?" "The relative homogeneity of nuclear size across the population" "The presence of multiple large nuclei within single cells" "Increased nuclear to cytoplasmic ratio" "Discrete cellular borders between adjacent cells" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4402.jpg" -"4403" "Based on the muscle fibers' diameter, which slide suggests a possible pathological hypertrophy?" "Left slide" "Right slide" "Both slides" "Neither slide" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4403.jpg" -"4404" "Based on the histopathological features observed in the epidermis, which type of cell alteration is most evident in this image?" "Spongiosis" "Acantholysis" "Vacuolar alteration" "Hyperkeratosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4404.jpg" -"4405" "Based on the examination of the tissue's extracellular matrix in this image, what is its likely composition?" "Loose connective tissue" "Nervous tissue" "Dense connective tissue" "Hyaline cartilage" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4405.jpg" -"4406" "What morphological feature indicates a loss of function within some of the glandular structures?" "Solid epithelial nests without lumen formation" "Multilayering of the epithelial cells" "Cilia on the apical surface of the epithelial cells" "Mucinous vacuoles with depleted staining" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4406.jpg" -"4407" "What is the pattern of cellular organization observed in this image?" "Organized in a nested architecture" "Spindle-shaped cells in a storiform pattern" "Disorganized and diffuse infiltration" "Arranged in a rosette formation" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4407.jpg" -"4408" "What is the appearance of the cytoplasm in the majority of the cells in this image?" "Basophilic" "Eosinophilic" "Amphophilic" "Clear" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4408.jpg" -"4409" "Assessing the tissue organization, how are cells arranged in the provided microscopic view?" "In a loose, disorganized pattern with areas of dense cellularity" "In a palisading arrangement around a central structure" "Around the well-formed vascular lumens" "In a well-organized and structured pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4409.jpg" -"4410" "What staining technique was likely used to produce the contrast seen in this renal tissue section?" "Hematoxylin and Eosin (H&E)" "Wright's Stain" "Masson's Trichrome" "Periodic Acid-Schiff (PAS)" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4410.jpg" -"4411" "How do the nuclei of the epithelial cells appear in this section of colon tissue?" "Small and hypochromatic" "Hyperchromatic and elongated" "Regular in size with pale staining" "Enlarged with multi-nucleation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4411.jpg" -"4412" "Analyzing the glandular structures, what can be inferred about the glandular lumens?" "Consistency of intraluminal secretions with necrotic debris" "Devoid of secretory material" "Filled with eosinophilic secretions" "Lined with multiple layers of epithelial cells" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4412.jpg" -"4413" "Compared to the surrounding cells, what is the appearance of the cytoplasm of the cell circled in red?" "The cytoplasm is scant and appears more basophilic" "The cytoplasm is abundant and appears more basophilic" "The cytoplasm is abundant and stains more eosinophilic" "The cytoplasm is scant and stains more eosinophilic" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4413.jpg" -"4414" "What characteristic of the surrounding cells can be observed that differentiates them from the circled cell?" "They have a central pallor indicative of red blood cells" "They exhibit a multi-lobed nucleus typical for monocytes" "They all have large, irregular nuclei" "They are larger in size with a more prominent nucleated appearance" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4414.jpg" -"4415" "What best describes the cellular arrangement observed in the endocrine area of the pancreatic tissue?" "Pale-staining cells with more sparse cellular arrangement" "Fiber-rich stroma with scattered cells" "Cells with clear cytoplasm arranged in a dense cluster" "Basophilic cells with granular cytoplasm dispersed throughout" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4415.jpg" -"4416" "What is the predominant characteristic of the inflammatory cells present in the central area of the artery?" "Predominantly macrophages with abundant foamy cytoplasm" "Predominantly lymphocytes with scant cytoplasm" "Predominantly neutrophils with dark, round nuclei" "Predominantly plasma cells with eccentric nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4416.jpg" -"4417" "What is the predominant staining pattern of the interstitial connective tissue in this histological section?" "Basophilic with a homogeneous appearance" "Eosinophilic with a homogeneous appearance" "Basophilic with numerous nuclei" "Eosinophilic with scattered nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4417.jpg" -"4418" "What structures can be identified as part of the nephron's tubular components in this image?" "Collecting ducts and transitional epithelium" "Proximal and distal convoluted tubules" "Ureteric bud and bladder urothelium" "Thick and thin segments of the loop of Henle" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4418.jpg" -"4419" "What characteristic of the glandular cells can be observed in this histological image?" "Variation in cell size and shape" "An abundance of foamy, vacuolated cytoplasm" "The presence of abundant cytoplasmic keratinization" "The cells exhibit uniformity in size and shape" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4419.jpg" -"4420" "What is the predominant tissue type observed in the histological section?" "Dense irregular connective tissue" "Adipose tissue" "Cardiac muscle tissue" "Dense regular connective tissue" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4420.jpg" -"4421" "What is the predominant cellular morphology seen within the well-circumscribed nodules?" "Spindle-shaped cells with an abundance of cytoplasm" "Tightly packed round cells with scant cytoplasm" "Pleomorphic cells with an irregular nuclear contour" "Multinucleated giant cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4421.jpg" -"4422" "Evaluate the cellular architecture and indicate which description fits the observed pattern in the tissue sample." "Clear lobular configuration" "Disrupted structural arrangement" "Organized glandular architecture" "Unidirectional cellular orientation" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4422.jpg" -"4423" "Based on the histological features observed, what is the predominant cell type making up the cellular aggregates with darkly stained nuclei?" "Lymphocytes" "Fibroblasts" "Neoplastic cells" "Adipocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4423.jpg" -"4424" "What can be said about the cellularity of the tissue in the provided histopathological image?" "The cells have a low nucleus to cytoplasm ratio" "The cells demonstrate clear cytoplasm with centrally placed nuclei" "The cells display a high nucleus to cytoplasm ratio" "The cells show abundant cytoplasm with peripheral nuclei arrangement" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4424.jpg" -"4425" "What type of distinctive inclusion is noticeable within some of the cells?" "Dark blue hematoxylin bodies" "Lipofuscin granules" "Red eosinophilic droplets" "Pale basophilic stippling" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4425.jpg" -"4426" "What typical lymph node architectural feature is noticeably absent in this histological section?" "Megakaryocytes in the interfollicular areas" "High endothelial venules" "Adipocytes within the germinal center" "Hassall's corpuscles" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4426.jpg" -"4427" "What is the predominant cellular morphology observed in this tissue section?" "Spindle-shaped cells with ovoid nuclei" "Round to polygonal cells with abundant cytoplasm" "Cuboidal cells lining a ductal structure" "Disorganized cells with hyperchromatic nuclei" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4427.jpg" -"4428" "In this image, what is the status of the granulomas with regard to necrosis?" "Fibrinoid necrosis present" "Suppurative with abscess formation" "Non-caseating without central necrosis" "Caseating with central necrosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4428.jpg" -"4429" "Based on the histopathological features present, which feature is NOT evident in this image?" "Multinucleated giant cells" "Fibrosis adjacent to granulomas" "Mixed inflammatory infiltrate" "Epithelioid histiocytes" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4429.jpg" -"4430" "What notable nuclear feature is present in the hepatocytes of this liver tissue sample?" "Uniformly large and pleomorphic nuclei" "Uniformly small and hypochromatic nuclei" "Multiple nuclei within a single hepatocyte" "Enlarged and hyperchromatic nuclei" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4430.jpg" -"4431" "How would you describe the arrangement of the liver cells in this image?" "Disorganized architecture with loss of normal trabecular arrangement" "Normal cord-like trabecular arrangement" "Hyperplastic nodular arrangement" "Regular rosette-like pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4431.jpg" -"4432" "What is the morphology of the cells lining the glandular structures in this breast tissue section?" "Squamous in shape with abundant cytoplasm" "Columnar with basal-oriented nuclei" "Cuboidal with central rounded nuclei" "Spindle-shaped with hyperchromatic nuclei" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4432.jpg" -"4433" "What feature in the tissue can be associated with the presence of calcifications?" "Eosinophilic secretion within ducts" "Areas of increased cellular atypia and mitosis" "Dense collagen bundles in the stroma" "The presence of multi-nucleated giant cells" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4433.jpg" -"4434" "Based on the microscopic features observed, what is the predominant nuclear characteristic of the cells within the tissue?" "Large nuclei with prominent nucleoli and clear cytoplasm" "Uniform, small nuclei with abundant cytoplasm" "Small, round nuclei with a high nucleus-to-cytoplasm ratio" "Hyperchromatic nuclei with varying shapes and sizes" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4434.jpg" -"4435" "What tissue type is observed forming the walls of the cyst that is adjacent to the cystic space?" "Stratified columnar epithelium" "Simple squamous epithelium" "Stratified squamous epithelium" "Transitional epithelium" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4435.jpg" -"4436" "What is the predominant feature of the cells within the highlighted area of the tissue section?" "Abundant, vacuolated, pale staining cytoplasm" "Hyperchromatic nuclei with high nuclear-to-cytoplasmic ratios" "Necrotic cells with loss of membrane integrity" "Eosinophilic cytoplasm with spindle-shaped morphology" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4436.jpg" -"4437" "What does the extracellular matrix area in the tissue section predominantly consist of?" "Adipose tissue with empty-looking, clear spaces" "Dense irregular connective tissue with scattered fibroblast nuclei" "Pink to red-hued connective or stromal tissue" "Hyaline cartilage with a glassy, blue appearance" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4437.jpg" -"4438" "What does the pale halo surrounding the dark-staining circles within the structures indicate?" "Cell nuclei" "Cytoplasmic matrix" "Myelin sheath" "Collagen fibers" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4438.jpg" -"4439" "Based on the structure indicated by the arrow, what type of vessel does it represent within the liver tissue?" "Hepatic vein with thin-walled structure" "Portal vein with wide lumen" "Hepatic artery with thick muscular wall" "Central vein lacking supporting connective tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4439.jpg" -"4440" "Based on the observed histological patterns and cellular distribution, the tissue section likely represents which phase of the ovarian cycle?" "Menstrual phase" "Follicular phase" "Proliferative phase" "Luteal phase" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4440.jpg" -"4441" "What can be inferred about the cytoplasmic to nuclear size ratio in the cells shown in this image?" "The cells have a low nucleus to cytoplasm ratio" "The cells have a high nucleus to cytoplasm ratio" "The cells have a balanced nucleus to cytoplasm ratio" "The cells have no discernible nucleus to cytoplasm ratio" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4441.jpg" -"4442" "Based on the morphology of the cells in this microscopic image, what is the most likely characteristic of the nuclei?" "Multiple inconspicuous nucleoli within the nuclei" "Single, prominent nucleoli within the nuclei" "Nuclear inclusions within large, prominent nuclei" "Multinucleation with small, uniform nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4442.jpg" -"4443" "Analyzing the density of the inflammatory infiltrate and the target of the inflammation, what dermatologic condition might the tissue represent?" "Melanoma" "Psoriasis" "Alopecia Areata" "Lichen Planus" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4443.jpg" -"4444" "By closely examining the epithelial cells lining the tubular structures, what can be inferred about their state?" "They exhibit hyperplastic changes with an increased number of layers" "They show signs of significant atypia and pleomorphism" "They appear necrotic with loss of nuclear detail" "They are hypertrophic with an increase in cell size" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4444.jpg" -"4445" "What cytoplasmic characteristic can be observed in the columnar epithelial cells?" "Basophilic cytoplasm" "Eosinophilic cytoplasm" "Clear cytoplasm" "Granular cytoplasm" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4445.jpg" -"4446" "How do Kupffer cells, seen scattered among the hepatocytes, appear morphologically in this image?" "Large cells with pale cytoplasm and multiple nuclei" "Cells with clear cytoplasm and peripheral nuclei" "Darker-staining cells with elongated nuclei" "Cells with granular cytoplasm and hyperchromatic nuclei" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4446.jpg" -"4447" "What is the likely histopathological feature indicated by the clear, rounded inclusions within the hepatocytes?" "Mallory bodies related to alcoholic liver disease" "Glycogen accumulations" "Bile accumulations due to cholestasis" "Lipid vacuoles indicative of steatosis" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4447.jpg" -"4448" "Considering the appearance of the cells at the bottom of the image, what type of cellular modification can be observed?" "Presence of cellular inclusions" "Cell enlargement indicative of hypertrophic chondrocytes" "Cell shrinkage due to apoptosis" "Necrosis with loss of cellular detail" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4448.jpg" -"4449" "Based on the organization of the cells in the tissue section, how would you describe their arrangement?" "Arranged in clusters or aggregates" "Randomly dispersed without a clear pattern" "Forming large, multi-nucleated syncytia" "Arranged in rows resembling stacks of coins" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4449.jpg" -"4450" "Which feature in the image primarily indicates the presence of mucin within the glandular cells?" "The presence of a uniform, light cytoplasmic staining throughout the tissue section" "The presence of dark staining characteristic within some glandular cells" "The presence of a clear, unstained area surrounding the glandular cells" "The presence of a homogenous staining pattern across all glandular cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4450.jpg" -"4451" "Which feature of the dense cell aggregation suggests the presence of a neoplasm?" "Well-organized connective tissue stroma" "Basaloid appearance of cells" "Pinkish-red staining of collagen fibers" "Homogenous eosinophilic centers" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4451.jpg" -"4452" "What feature is prominent in the stratum corneum of this histological section?" "Parakeratosis with retained nuclei" "Hypergranulosis with thickened granular layer" "Acantholysis with loss of intercellular connections" "Orthokeratosis with basket-weave pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4452.jpg" -"4453" "The cells directly beneath the epidermis lack a characteristic feature of normal maturation. What is this feature?" "Lack of keratinization" "Lack of pigment production" "Lack of intercellular bridges" "Lack of vertical maturation" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4453.jpg" -"4454" "Considering the background tissue observed in the image, in what area of the skin's anatomy are the cells most likely located?" "Submucosa" "Epidermis" "Hypodermis" "Dermis" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4454.jpg" -"4455" "What type of pigmentation is predominantly visible within the cells observed in the microscopic image?" "Bilirubin" "Melanin" "Hemosiderin" "Lipofuscin" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4455.jpg" -"4456" "Assuming the presence of goblet cells within the stratified squamous epithelial layer, what distinguishes these cells from surrounding epithelial cells?" "A lighter-staining cytoplasm and a dark-staining nucleus" "Multinucleation within a basophilic cytoplasm" "A darker-staining cytoplasm and smaller nucleus" "A clear cytoplasm with absence of nucleus" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4456.jpg" -"4457" "What is indicated by the presence of deeper staining cells in the superficial dermis?" "Presence of neutrophilic infiltration" "Accumulation of melanophages" "Keratinocyte proliferation" "Increase in mast cells" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4457.jpg" -"4458" "What characteristic feature is indicated by the yellow arrows in the microscopic image?" "Dark pink or red cytoplasm" "Pale-staining cytoplasm" "Blue-purple cytoplasm" "Clear cytoplasm with no visible structures" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4458.jpg" -"4459" "Based on the cellular features highlighted by the pink arrows, what type of cells can be inferred?" "Cells with prominent nucleoli and dark staining" "Cells with highly granular and dense cytoplasm" "Cells with abundant cytoplasm taking up the stain strongly" "Chromophobe cells with pale-staining cytoplasm" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4459.jpg" -"4460" "The cells embedded in the myxoid matrix have a characteristic appearance. What is the shape of these cells primarily?" "Squamous" "Spindle-shaped" "Cuboidal" "Round or oval" "D" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4460.jpg" -"4461" "Based on the eosinophilic material present, which feature of the tissue can be identified?" "Neural tissue" "Dense fibrous connective tissue" "Vascular tissue" "Adipose tissue" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4461.jpg" -"4462" "Based on the morphology of the tissue observed, what is the histopathological condition depicted?" "Acantholysis" "Hyperkeratosis" "Spongiosis" "Acanthosis" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4462.jpg" -"4463" "How would you describe the cytoplasm of the cells in the densely cellular regions of this tissue section?" "Abundant and eosinophilic" "Sparse and basophilic" "Sparse and eosinophilic" "Abundant and basophilic" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4463.jpg" -"4464" "The elongated, slit-like structures within the tissue are suggestive of what type of tissue change?" "Necrosis within the stroma" "Keratin pearl formation" "Neovascularization" "Hyaline degeneration" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4464.jpg" -"4465" "What characteristic of the cytoplasm in most cells is apparent in this tissue sample?" "Basophilic (blue to dark purple staining)" "Eosinophilic (pink staining)" "Clear with no visible staining" "Homogeneous dark purple staining" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4465.jpg" -"4466" "What is the most likely identity of the multi-vacuolated cells based on their morphological features?" "Adipocytes" "Hepatocytes" "Renal tubular cells" "Macrophages" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4466.jpg" -"4467" "Based on the stain characteristics and granularity, what cellular component is likely abundant in the cells with pink-staining cytoplasm?" "Lysosomes" "Ribosomes" "Mitochondria" "Endoplasmic reticulum" "C" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4467.jpg" -"4468" "In the context of the tissue architecture seen in this microscopic image, how would you describe the appearance of the extracellular matrix or stroma?" "Pink-stained, varying in thickness and creating a network" "Thick, homogenous, and evenly dispersed" "Acellular with hyaline deposits" "Blue-stained with a fibrous, reticular pattern" "A" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4468.jpg" -"4469" "Considering the morphology of the nuclei in the cells shown in the image, which description best matches their appearance?" "Clearly visible with prominent nucleoli" "Mostly obscured or not clearly delineated" "Uniform and centrally located in the cells" "Hyperchromatic with irregular shapes" "B" "EduContent" "multiple-choice" "/simple-eval-dataset-loader-dev/dataset/vlmevalkit/images/PathMMU_TEST/4469.jpg"