Input: The broad range protein tyrosine kinase inhibitor genistein and the phosphatidylinositol 3-kinase inhibitors wortmannin and LY 294002 (2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one) also blocked adenosine A3 receptor stimulation of p42/p44 MAPK.

protein tyrosine kinase

phosphatidylinositol 3-kinase

adenosine A3 receptor


Input: Defective concanavalin A-induced suppression in bancroftian filariasis.

concanavalin A


Input: Rising antibody titres to the astrovirus particles were demonstrated in one child, and IgM was also demonstrated in this patient' s serum.

IgM


Input: Demonstration of changes in fetal liver erythropoiesis using echo-planar magnetic resonance imaging.


Input: Conversely the rate of bioavailability was significantly different, because from the Reference patch the release rate is fast in the first 24 h, leading to an E2 peak at 8 h and to a Cmax in average at 23 h.


Input: Effects of dexamethasone on the development of radiation nephropathy in the rat.


Input: Reaction of aromatic/heterocyclic sulfonamides possessing free amino, imino or hydrazino moieties with 7-chloro-4-chloromethylcoumarin afforded a series of N-[(7-chloro-4-coumarinyl)-methyl]-derivatives which showed effective inhibition of three carbonic anhydrase (CA) isozymes.

carbonic anhydrase

CA


Input: The present study also emphasizes the need of establishing dose-response curves to correctly assess the relative contribution of the different regions of steroid hormone receptors in activation of transcription.

steroid hormone receptors


Input: (1986) described optic nerve degenerations in patients with Alzheimer' s disease and Sadun published a dropout of retinal ganglion cells that range from 30% to 60%.


Input: In addition, these results suggest that the interactions, and consequently the mechanisms, governing transcriptional activation by CTF are distinct from those mediating DNA replication.

CTF


Input: These proteins, called variant surface glycoproteins (VSGs), are expressed from a specific locus, the VSG gene expression site (ES).

variant surface glycoproteins

VSGs

VSG gene expression site (ES)


Input: The temporal changes in the plasma concentration of immunoreactive atrial natriuretic factor (iANF) were studied in six conscious dogs with an arteriovenous (AV) fistula, a model of chronic high-output heart failure.

immunoreactive atrial natriuretic factor

iANF


Input: In situ hybridization of whole-mount mouse embryos with Mex5 antisense RNA provide no evidence for the exclusion of Mex5 during embryonic development.

Mex5 antisense RNA


Input: Karyo-and cytometric investigations of cortical layer V pyramidal neurons of albino rat after three various fixations


Input: The cloning of human apo B-100 has provided new insights into the structure and physicochemical properties of apo B-100 and will facilitate studies on the factors modulating apo B-100 biosynthesis and the expression of the apo B-100 gene in patients with dyslipoproteinemias.

human apo B-100

apo B-100

apo B-100

apo B-100 gene


Input: In the green unicellular alga Chlamydomonas eugametos, cellular division is readily synchronized by light/dark cycles.


Input: Northern blot analysis linked Plk expression to the proliferative activity of cells and tissues.

Plk


Input: A 1. 5-month-old boy with Sandifer' s syndrome is described.


Input: A 40-fold stimulation of chloramphenicol acetyltransferase activity mediated by four tandem repeats of the SNE could be induced within 2 h (and up to 250-fold within 6 h) after addition of TPA in DNA-transfected U-937 cells, indicating that the stimulation appeared likely to be a true protein kinase C-mediated signal transduction event rather than a differentiation response.

chloramphenicol acetyltransferase

SNE

protein kinase C


Input: A silica-based, fluoride-free placebo containing NaTPP, and a NaF-containing silica-based USP reference standard toothpaste were used as negative and positive control toothpastes, respectively.


Input: Molecular cloning of the alpha-globin transcription factor CP2.

alpha-globin transcription factor CP2


Input: The present study tries to associate some of the causes of hot ischaemia during the agony of the corpse donor and to evaluate those that may be caused by sympathetic efference during removal.


Input: The cost and effectiveness of nurse education--1.


Input: Between 1988 and 1995, 341 children with acute myeloid leukaemia (AML) were treated on the Medical Research Council Acute Myeloid Leukaemia Trial (MRC AML10).


Input: Using the yeast two-hybrid system, we have isolated an 835 amino acid RING finger (C3HC4 zinc finger) protein, TIF1 beta (also named KAP-1), that specifically interacts with the KRAB domain of the human zinc finger factor KOX1/ZNF10.

TIF1 beta

KRAB domain


Input: The N-terminal sequences of isoforms beta to epsilon contain a PEST region which could induce rapid intracellular degradation of isoforms beta and delta.


Input: Their central projections were indistinguishable from those of control axons in all four trigeminal subnuclei.


Input: Typicality is probably a better representation of Alexander, Dunbar and others' conclusions than specificity, which was always too absolute a term.


Input: We then developed a yeast artificial chromosome (YAC) contig for this region.


Input: In addition to TAK1, TGF-beta also stimulated JNK activity.

TGF-beta

JNK


Input: The study was carried out according to the BSI (1980) recommendations for testing restorative materials in vivo.


Input: A case report.


Input: Sixteen patients on maintenance hemodialysis underwent dialysis with either cuprophane (n = 8) or polymethylmethacrylate (PMMA; n = 8) membranes for 1 week and then switched to the opposite membrane during the second week.


Input: No significant difference in plasma ET levels was found between cardiac and peripheral sampling sites (pulmonary artery; 1. 07 +/-0. 28, right atrium; 1. 02 +/-0. 28, peripheral artery; 1. 12 +/-0. 23, peripheral vein; 1. 14 +/-0. 38 fmol/ml: N. S.), or among patients with uncomplicated MI, unstable angina (1. 00 +/-0. 32 fmol/ml), and healthy subjects (1. 01 +/-0. 29 fmol/ml).

ET


Input: Oxalates and the digestive tract


Input: Analysis of the MCV-1 RPO1 revealed high amino acid homologies to the corresponding polypeptides of vaccinia and variola virus.

MCV-1 RPO1


Input: This interaction is functional as it leads to retargeting of NF-kappa B p50 from the nucleus to the cytoplasm.

NF-kappa B p50


Input: Point mutations of Stat3 within the interacting domains blocked both physical interaction of Stat3 with c-Jun and their cooperation in IL-6-induced transcription directed by the alpha (2)-macroglobulin enhancer.

c-Jun

alpha (2)-macroglobulin enhancer


Input: Identification of masked toxins in the exotoxin complex of Staphylococcus pyogenes und Cl. perfringens; significance of their existence for clarifying of the masking mechanism


Input: Correlation coefficients between SF thickness and NIR optical density readings at 940 nm (OD1) and 950 nm (OD2) wavelengths ranged from r =-0. 30 (subscapula) to r =-0. 67 (biceps) for OD1 and r =-0. 39 (axilla) to r =-0. 68 (biceps) for OD2.


Input: Transfer of health care to natives holds much promise, lecturers say.


Input: In the second group, which consisted of babies of 33 to 36 weeks of gestational age, haptoglobin was detected in 6 infants, with levels less than 25 mg/dl in 3.

haptoglobin


Input: The clinical picture, the light and electron microscopic appearance, and the histochemical findings are described in six cases of fibroma of tendon sheath.


Input: We hypothesize that the ability of these acidic activators to specifically interact with multiple components of the transcription initiation complex likely underlies the dramatic functional synergy exhibited by this class of activation domains in vivo.


Input: High and pathological PAI-1 levels before and after the VO test were consistent with a defective fibrinolytic potential due to the inhibitory effect of PAI-1 on plasminogen activation.

plasminogen


Input: S. aureus leakage into the totally submerged test specimens was detected in 1 of 5 samples incubated for 4 weeks, while no leakage was detected in specimens incubated for 3, 5, 6, 7, and 8 weeks.


Input: MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK.

MAPKK kinase

MEKK

MAPK kinase

MEK

MAPK


Input: The Prompt and Praise condition was superior to the other two conditions in encouraging participation in low-interest recreational activities.


Input: The author describes the technique in detail and presents the findings for 25 patients (10 men and 15 women) examined for suspected ileostomy dysfunction, recurrent Crohn' s disease or ileal obstruction remote from the stoma.


Input: Biochemical studies have identified a cellular non-P element-encoded DNA binding protein, termed the inverted repeat binding protein (IRBP), that specifically interacts with the outer half of the 31-bp terminal inverted repeats.

non-P element-encoded DNA binding protein

inverted repeat binding protein

IRBP


Input: These findings suggest that eIF5-eIF2beta interaction plays an essential role in eIF5 function in eukaryotic cells.


Input: The delayed activation of the prostaglandin G/H synthase-2 promoter in bovine granulosa cells is associated with down-regulation of truncated upstream stimulatory factor-2.

prostaglandin G/H synthase-2

upstream stimulatory factor-2


Input: Nb2-11C cells expressed three PNR-related mRNA transcripts of 2. 5, 3. 0 and > 10 kb.

PNR-related mRNA transcripts


Input: E1A + cHa-ras transformed rat embryo fibroblast cells are characterized by high and constitutive DNA binding activities of AP-1 dimers with significantly altered composition.

cHa-ras

AP-1 dimers


Input: In the present study we have used Southern blot analysis to demonstrate that TSG6 is a single-copy gene in the human and murine species.


Input: CONCLUSIONS: Latanoprost administered once daily was significantly more effective in reducing IOP compared with unoprostone administered twice daily in patients with POAG and OH.


Input: Activation of HIV gene expression by UV must therefore involve additional cellular processes, such as those triggered by DNA damage, for generation of a full gene expression response.


Input: One promoter, p53P1, is located 100-250 bp upstream of the 218-bp noncoding first exon; a second, stronger promoter, p53P2, maps within the first intron.


Input: Hydropathy analysis of deduced A4 amino acid sequence revealed four putative membrane-spanning alpha-helices.


Input: This study includes 200 patients treated from 1964 to 1978, with an age range from 15 to 102 years, who required 329 generators.


Input: There is little similarity among the sequences upstream from the CAP site of the Spec2 genes except the TATA consensus sequence and a repeating trinucleotide, AAC.

Spec2 genes


Input: Radiological imaging such as UGI series and CT scan was useful to arrive at an accurate diagnosis.


Input: A case of acquired immune deficiency syndrome before 1980.


Input: In the promoters of many immediate early genes, including c-fos, CArG DNA regulatory elements mediate basal constituitive expression and rapid and transient serum induction.

immediate early genes

c-fos


Input: We propose that optimal transcription of the gD gene depends on the interaction of ICP4 with multiple binding sites across the gene and cellular factors that recognize specific sequence elements in the promoter.

gD gene


Input: Strains lacking a functional RPL16A gene grow as rapidly as wild type, whereas those containing a null allele of RPL16B grow more slowly than wild type.

functional RPL16A gene


Input: Maduromycosis in Italy


Input: Cetn1 possesses the sequence features of an expressed retroposon: the gene lacks introns, the open reading frame is not interrupted by stop codons, and the coding region is flanked by a pair of direct repeats.


Input: Substitutions of Asp11 led to dominant lethality.


Input: The Sty1 kinase is stimulated by a variety of different stress conditions including osmotic and oxidative stress and heat shock.

Sty1 kinase


Input: Acute toxicity tests were conducted to measure the response of first instar Toxorhynchites splendens to commonly used mosquito adulticides: malathion, naled and resmethrin.


Input: We prospectively studied serum prolactin (PRL) elevation after different types of documented seizures in 17 patients.

serum prolactin

PRL


Input: To further identify the residues responsible for the activity, we isolated the mutant viruses that were not neutralized with the soluble form of MHV receptor proteins, since such mutants were expected to have mutations in amino acids responsible for receptor-binding activity.

MHV receptor proteins


Input: When lipid X was combined with ticarcillin, survival differences were both significant and prolonged.


Input: Furthermore, the secondary stress responses were more pronounced and the ability to recover from them seemed to be impaired in exposed fish as compared to unexposed fish.


Input: Focal glomerulosclerosis-like disease with nephrotic syndrome in a horse.


Input: In addition, both activated Ral-GDS-like factor and Raf stimulate cyclin D (1) transcription and E2F activity and act in synergy with PI 3-kinase.

Ral-GDS-like

Raf

cyclin D (1)

PI 3-kinase


Input: Treatment with polyinosinic-polycytidylic acid to induce expression of Cre resulted in complete disruption of the Arnt gene and loss of ARNT messenger RNA (mRNA) expression in liver.

Cre

Arnt gene

ARNT messenger RNA


Input: Twelve patients of leprosy with arthritis and 161 patients without arthritis were studied for immunological parameters like immunoglobulins (IgG, IgM, IgA), C-reactive proteins and rheumatoid factor.

immunoglobulins

IgG

IgM

IgA

C-reactive proteins

rheumatoid factor


Input: The biological functions of rat surfactant protein A (SP-A), an oligomer composed of 18 polypeptide subunits derived from a single gene, are dependent on intact disulfide bonds.

surfactant protein A

SP-A


Input: DIC and low grade fibrinolysis may account for the coagulation abnormalities of the syndrome.


Input: All depressive groups showed improved error measures post-treatment.


Input: Plasmid subclones of the hr1a-containing AcMNPV HindIII-N fragment were examined for their ability to replicate in virus-infected (Spodoptera frugiperda) Sf9 cells, and to stimulate transcription when linked in cis with a 39K gene promoter-beta-glucuronidase fusion and cotransfected into cells along with a plasmid (ple-1) containing the gene encoding the trans-acting factor IE-1.

HindIII

39K gene promoter-beta-glucuronidase fusion


Input: This new receptor, TOR (thymus orphan receptor), is most closely related in both its DNA-binding domain and ligand-binding domain, 90% and 53%, respectively, to ROR alpha/RZR alpha and clusters with these two receptors and RZR beta in a phylogenetic tree, when both the DNA-binding domain and the ligand-binding domain sequences of nuclear receptors are compared.

TOR

thymus orphan receptor

ROR alpha

RZR alpha

RZR beta


Input: Immunofluorescence tests for Borrelia burgdorferi serum antibodies had positive results, but G-penicillin treatment was ineffective.

Borrelia burgdorferi serum antibodies


Input: Laser soldering with exogenous fibrinogen is feasible without topical administration of additional clotting agents, significantly improves the bursting strength of primary laser welded anastomoses, and appears to result from urokinase-resistant fibrinogen cross-linking.

fibrinogen

urokinase

fibrinogen


Input: Raman scattering from VO2 single crystals: A study of the effects of surface oxidation.


Input: Left ventricular insufficiency requires two SP/patient, with good results in approximately 81 p. cent.


Input: Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity.

human thioredoxin reductase


Input: 50-fold increase in foreign protein production.


Input: A rare tRNA-Arg (CCU) that regulates Ty1 element ribosomal frameshifting is essential for Ty1 retrotransposition in Saccharomyces cerevisiae.

tRNA-Arg (CCU)

Ty1 element


Input: In addition, putative binding sites for SH3 and SH2 domains are present in the amino-terminal half of the molecule.

SH2 domains


Input: The technique used by this system involves a transient, externally applied increase in resistance to breathing.


Input: Copyright 1999 Academic Press.


Input: Vorozole (Rivizor) is a potent and stereospecific inhibitor of aromatase having shown promising endocrine effects in phase I studies.

aromatase


Input: Mapping the 5' and 3' termini of TED RNAs indicated that the LTRs have a retroviral U3-R-U5 structural organization that is capable of directing the synthesis of transcripts that represent potential substrates for reverse transcription and intermediates in transposition.

TED RNAs


Input: A Meis1 cDNA clone that encoded a novel member of the homeobox gene family was identified.

Meis1 cDNA

homeobox gene family


Input: Cellular lysates were analyzed for luciferase and beta-galactosidase activities.

luciferase

beta-galactosidase


Input: The protein contains a SHAQKYF amino acid signature motif in the second myb-like repeat, which is highly conserved in a number of recently identified plant myb-related genes, thus defining a new class of plant DNA-binding proteins.

myb-like repeat

plant myb-related genes


Input: However, sphincter length decreased with age from 24. 3 to 14. 8 mm., maximal urethral pressure from 88. 7 to 55 cm. water and maximal urethral pressure during voluntary contraction from 221. 4 to 166. 3 cm. water.


Input: The DF3/MUC1 gene encodes a high molecular weight mucin-like glycoprotein which is overexpressed at the transcriptional level in the majority of human breast cancers.

high molecular weight mucin-like glycoprotein


Input: A cephalothoracophagus disymmetros buffalo calf.


Input: In 32 of them the results of an exercise performance test based on heart rate response to submaximal exercise (VO2, 170 [bpm]) was compared with another index of physical performance capacity, which is independent from heart rate: the ventilatory threshold.


Input: Treatment with KP-45 preparation usually resulted in partial regression of tumor growth, accompanied by improvement of the clinical state of these patients, as well as reappearance of normal values of blood picture and biochemical parameters.


Input: Electromobility shift analysis using oligonucleotides encompassing the proximal, distal, and BED/AP-1-binding regions failed to demonstrate selective transactivation after CD2 signaling of LPMC.


Input: Four families of homing endonucleases have been identified, including the LAGLIDADG, the His-Cys box, the GIY-YIG and the H-N-H endonucleases.

homing endonucleases

LAGLIDADG

His-Cys box

GIY-YIG

H-N-H endonucleases


Input: The use of aluminum hydroxide was associated with an increase in fecal fluoride excretion and a decrease in net absorption of fluoride regardless of the intake fluoride, calcium, phosphorus, or magnesium.


Input: Administration of SnCl2 and ZnSO4 (group V) resulted in a decrease of ALA-D activity and in an increase in CP-U.

ALA-D


Input: Coexistence of Turner' s syndrome and schizophrenia


Input: A selectable marker for transformation was constructed by transcriptional fusion of a Ustilago maydis heat shock gene promoter with the hygromycin B phosphotransferase gene of Escherichia coli.

Ustilago maydis heat shock gene promoter

hygromycin B phosphotransferase gene of Escherichia coli


Input: Moreover, FACT specifically interacts with nucleosomes and histone H2A/H2B dimers, indicating that it may work by promoting nucleosome disassembly upon transcription.

FACT


Input: All exon/intron splice junctions follow the GT/AG rule.


Input: Acetoacetate decarboxylase (ADC) (EC4. 1. 1. 4) of Clostridium acetobutylicum DSM 792 was purified to homogeneity, and its first 25 N-terminal amino acids were determined.

Acetoacetate decarboxylase

ADC

EC4. 1. 1. 4


Input: These studies suggest that tandem alpha-helices located near the C-terminus of PC-TP facilitate membrane binding and extraction of phosphatidylcholines.

PC-TP


Input: In this study, we investigated the mechanism by which Tax activates gene expression in conjunction with members of the ATF/CREB family.

Tax

ATF

CREB


Input: Repression of the herpes simplex virus 1 alpha 4 gene by its gene product (ICP4) within the context of the viral genome is conditioned by the distance and stereoaxial alignment of the ICP4 DNA binding site relative to the TATA box.

herpes simplex virus 1 alpha 4 gene

ICP4 DNA binding site


Input: We studied 18 dogs, anaesthetised and spontaneously breathing both room air and after the inhalation of a gas mixture containing 10% CO2, 20. 9% O2, and 69. 1% N2, to determine the role of histamine, serotonin, and acidaemia in pulmonary hypertension produced by hypercapnia.


Input: Disaster medicine


Input: In both liver and pancreatic islet, glucokinase is subject to inhibition by a regulatory protein (GCKR).

glucokinase

GCKR


Input: At promoters that initiate with + 1 GGG, T7 RNAP synthesizes a ladder of poly (G) products as a result of slippage of the transcript on the three C residues in the template strand from + 1 to + 3.

T7 RNAP


Input: Transcription analysis of the EcoRI D region of the baculovirus Autographa californica nuclear polyhedrosis virus identifies an early 4-kilobase RNA encoding the essential p143 gene.

EcoRI D region

p143 gene


Input: Vectorcardiography in coronary patients with the electrocardiographic RS segment in the V1 lead


Input: In this second clinical paper, the genetic features of the case of microphthalmia in sheep reported by Wagenaar is discussed in greater detail.


Input: Both the arterial and venous thrombi were clearly discernible at 2 to 8 h after injection of 99Tcm-SZ-51.


Input: First aid.


Input: However, the blend of Metanil yellow and Orange II (1: 1) resulted in the D1 50. value of 288 min.


Input: A novel protein kinase C (PKC)-interacting protein was identified by the yeast two-hybrid screening using the regulatory domain of PKC beta I as a bait.

protein kinase C

PKC

PKC beta I


Input: In this study, we show that the activating effect of this mutation is not the result of creating an exonic splicing enhancer (ESE) or disrupting a putative secondary structure.


Input: The architecture of the hRap1 Myb domain is very close to that of each of the Myb domains from TRF1, scRap1p and c-Myb.

hRap1 Myb domain

Myb domains

c-Myb


Input: This was tragically highlighted by the death of a 17 year old dental nurse after taking a single 1 g tablet of sodium nitrite.


Input: However, this posttranslational modification of the gar2 protein does not appear to be essential for normal production of 18S rRNA.

gar2 protein

18S rRNA


Input: The BRSV L gene is 6573 nt in length and the derived polypeptide has 2162 aa.

BRSV L gene


Input: BRAP2 also shares significant homology with a hypothetical protein from yeast Saccharomyces cerevisiae, especially in the zinc finger region.


Input: We have isolated and determined the complete nucleotide sequence of another operon, cpeCD, that encodes the linker proteins associated with phycoerythrin hexamers in the phycobilisome.

cpeCD

phycoerythrin hexamers

phycobilisome


Input: Here, we describe the results of a detailed study aimed at identifying the gene or genes responsible for the rapid growth-arrest response obtained with human chromosome-9.


Input: A novel Cdc42Hs mutant induces cellular transformation.

Cdc42Hs mutant


Input: We identified Tyr (112) and Leu (175) within the RNA-binding domain of the U1 70K protein to be cross-linked to G (28) and U (30) in stem-loop I, respectively.

U1 70K protein


Input: In general, the scallop extract potentiated phototactic suppression.


Input: Magnetic field influence on central nervous system function.


Input: Only Staphylococcus xylosus SX63 was detected as a strain with high adherence activity.


Input: Macrophages: modulators of immunity.


Input: METHODS: The Die Deutsche Diabetes Dialyse Studie is a prospective randomized placebo-controlled trial that tests the hypothesis that atorvastatin, a hydroxymethyl-glutaryl coenzyme A reductase inhibitor, decreases the rate of cardiovascular mortality and of nonfatal myocardial infarction in patients with type 2 diabetes who have been on hemodialysis treatment for no more than two years.

hydroxymethyl-glutaryl coenzyme A reductase


Input: An OD 650 greater than 0. 15 appears to be a rapid, reliable indicator of fetal lung maturity.


Input: This high dose 5-FU + Act-D protocol was effective for drug resistant cases with MEA protocol.


Input: Therefore, it appears that GCN2 protein kinase function is stimulated posttranslationally in amino acid-starved cells.

GCN2 protein kinase


Input: CSEn stimulated transcription of a variety of promoters, including the hCS, human growth hormone, thymidine kinase, and Rous sarcoma virus promoters, in human choriocarcinoma cell lines (BeWo and JEG-3) but not HeLa cells or rat somatolactotrophes (GC).

CSEn

hCS

human growth hormone

thymidine kinase

Rous sarcoma virus promoters


Input: HIV-2 in Spain.


Input: Reversal of mefloquine resistance in rodent Plasmodium.


Input: Airborne rabies encephalitis: demonstration of rabies virus in the human central nervous system.


Input: No promoter activity could be detected with various mouse Fli-1 promoter-CAT constructs containing 600 bp of the 5' flanking region, the complete exon 1, the 5' end of intron 1 and/or retroviral LTR sequence.

mouse Fli-1 promoter

CAT


Input: We now show that the FRAP Ser2035--> Ala mutant displays similar binding affinity when compared with the wild-type protein, whereas all other mutations at this site, including mimics of phosphoserine, abolish binding, presumably due to either unfavorable steric interactions or induced conformational changes.

FRAP


Input: These findings suggest that the mechanism of ribosomal frameshifting at the PVM signal is different from the one described by the' simultaneous slippage' model in that only the string of four adenosine nucleotides represents the slippery sequence involved in a-1 P-site slippage.


Input: The fru gene has seven exons spanning 15-kb encoding two transcripts with ORFs of 841 and 695 amino acids.

fru gene


Input: This sequence can interact with at least two proteins in a fibroblast nuclear extract that have binding characteristics of an Ets family protein and a serum response factor-like protein.

Ets family protein

serum response factor-like protein


Input: Response properties of single units in the accessory optic system of the dark-reared cat.


Input: Effect of tetracycline on the glycogen-producing function of the liver and intestinal microflora in white mice


Input: Significantly higher levels of vitamin C and catalase activity were found in vegetarians (C-63. 6 and 86. 5 mumol/l; CAT-1497 and 1313 U/ml for males and females, respectively) when compared to nonvegetarians (C-41. 3 and 54. 4 mumol/l; CAT-1192 and 1086 U/ml).

catalase


Input: However, only plasma fibrinogen concentrations showed statistically significant positive associations with IMT in both groups.

plasma fibrinogen


Input: METHODS.


Input: Presently, we made chain pair switch, chimeric, and site mutant gamma delta TCRs and transfected them into TCR-mutant Jurkat T cells to examine the effects of changing the TCR gamma junctional region sequences on reactivity to prenyl pyrophosphate Ags.

mutant gamma delta TCRs

TCR gamma junctional region sequences

prenyl pyrophosphate Ags


Input: The molecular dynamics simulations provide insight into the conformational flexibility of these analogs.


Input: Modified Grocott' s methenamine silver nitrate method for quick staining of Pneumocystis carinii.


Input: The control of human aromatase expression is complex in that several promoters drive aromatase expression in a tissue-specific manner.

human aromatase

aromatase


Input: Surprisingly, although Mist1 binds to E-boxes in vivo, the Mist1 protein lacks a functional transcription activation domain.

Mist1 protein


Input: Selective upper abdominal sympathectomy increased basal acid output in rats but was without effect on stimulated acid output, serum gastrin concentration, and gastric mucosal histidine decarboxylase activity.

serum gastrin

gastric mucosal histidine decarboxylase


Input: To isolate genes that contain zinc finger motifs, a human brain cDNA library was screened with an oligonucleotide complementary to the conserved " linker " sequence between adjacent zinc fingers.


Input: Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site.

Transforming growth factor beta

cyclin-dependent kinase

Sp1 consensus site


Input: Thus, in addition to the previously characterized FAS-binding factor 1 interacting with the inositol/choline-responsive-element motif, a second motif common to the promoter regions of both FAS genes could be identified.

FAS-binding factor 1

FAS genes


Input: Kluyveromyces lactis, a budding yeast related to Saccharomyces cerevisiae, can grow on a wider variety of substrates and shows less sensitivity to glucose repression than does Saccharomyces cerevisiae.


Input: Sociological analysis of the family.


Input: Like other known GCD genes, GCD14 and GCD15 are therefore probably required for general translation initiation in addition to their roles in GCN4-specific translational control.

GCD genes


Input: Sorting information to the chloroplastic inner envelope is contained in an NH2-proximal part of mature IEP110 (110N).

mature IEP110


Input: Both algorithms have been implemented and applied to data simulated for a scanner with a large axial aperture (30 degrees), and also to data acquired with the ECAT HR and the ECAT HR + scanners.


Input: BACKGROUND: Murine Nramp is a candidate for the macrophage resistance gene Ity/Lsh/Bcg.

Murine Nramp

Ity

Lsh

Bcg


Input: Serum zinc and copper levels and urine copper concentrations in men were significantly lower than in women, while there were no differences in serum or urinary zinc and copper levels with age.


Input: Pregnancy was ensued in 4 cases in group I.


Input: CONCLUSION: In these patients control of ventricular response rate with either HBA + VVIR pacemaker or atrioventricular modifying drugs + VVI pacemaker will lead to a significant improvement in exercise duration and quality of life.


Input: Western immunoblot analysis detected p55gag and its cleavage products p39 and p27 in purified particles derived by expression of gag and gag-pol, respectively.

gag

gag

pol


Input: These three phases of cyclin E association with chromatin may facilitate the diverse activities of cyclin E--Cdk2 in initiating replication, blocking rereplication, and allowing resetting of origins after mitosis.

cyclin E

cyclin E


Input: It has been shown that renin secretion is stimulated by endothelin, a recently discovered peptide with strong vasoconstrictive properties and stimulating effects on renin secretion.

renin

endothelin

renin


Input: A higher percentage of children with cerebral malaria (40 per cent) than with non-cerebral malaria (29 per cent) or controls (20 per cent) also had either serum ferritin < 100 micrograms/l and inflammation or sTfR > 7. 3 mg/l or both.

serum ferritin

sTfR


Input: Patients received BPB using bupivacaine 2 mg kg-1 with adrenaline 1 in 200, 000, either with or without hyaluronidase 3000 iu, in a volume of 0. 5 ml per 2. 54 cm of the patient' s height.

hyaluronidase


Input: The rifampicin resistance of uvsW-repressed replication suggests that it involves either tertiary initiation or some novel mode of initiation.

uvsW


Input: Association between hyperhomocysteinemia and ischemic heart disease in Sri Lankans.


Input: These findings suggest that the proteolipids of the vacuolar H +-ATPases were evolved in parallel with the eubacterial proteolipid, from a common ancestral gene that underwent gene duplication.

vacuolar H +-ATPases


Input: Coexpression of c-Rel in combination with ATF-1, CREB2, or ATF-1/CREB2 leads to synergistic transactivation of a CD28RE-TRE reporter plasmid in quiescent Jurkat T-cells.

c-Rel

CD28RE-TRE reporter


Input: Characterization of a cDNA encoding CNN predicts a novel structural protein with three leucine zipper motifs and several coiled-coil domains exhibiting limited homology to the rod portion of myosin.

cDNA encoding CNN

myosin


Input: It is suggested that the loss of weight, the decrease in food intake and the increase in brain MOPEG-SO4 induced by cyanamide reflect possible anorectic properties of the drug.


Input: The differential diagnosis of mineral oil lipidosis in lymph nodes with reaction to radiopaque oils and Whipple' s disease is discussed.


Input: The serum levels of cortisol and prolactin after nasal instillation of a suspension of vaginal exudate showed lower values than in control conditions (nasal instillation of saline).

prolactin


Input: This enhancer element functioned in a position-and orientation-independent manner both on the Pax-QNR P0 promoter and the heterologous thymidine kinase promoter.

Pax-QNR P0 promoter

heterologous thymidine kinase promoter


Input: The data when used to stimulate the collection of the information at antenatal or postnatal visits, nonetheless provide an accurate description of under-3 mortality trends and differences for the two periods examined--before 1984 and before 1989.


Input: The BHV-1 UL24, UL25, UL26 and UL26. 5 transcripts all terminated at a common 3'-polyadenylation site and varied significantly in their relative abundance.

BHV-1 UL24

UL26. 5 transcripts


Input: A.


Input: Ligand binding of multi-chain antigen receptors and hematopoietin/cytokine receptors results in rapid activation of protein tyrosine kinase (PTK)-dependent signalling molecules such as phosphatidylinositol 3-kinase (PI 3-kinase).

hematopoietin

protein tyrosine kinase

PTK

phosphatidylinositol 3-kinase

PI 3-kinase


Input: Post-CPB cardiac index was superior in group B (3. 9 +/-0. 3 vs.


Input: The regulatory genes cnrYXH have been cloned, overexpressed, and purified in Escherichia coli.

cnrYXH


Input: Cognitive measures of attention included the Stroop and Controlled Oral Word Association Test using the letters " C, " " F, " and " L " (COWAT, CFL version).


Input: The objectives of this study were 1) to quantify the comparative structural static and fatigue properties of the pointe shoe toe box, and 2) to evaluate the preferred shoe characteristics as determined by a survey of local dancers.


Input: When linked to the herpes simplex thymidine kinase minimal promoter, this fragment acts as an enhancing element in Rcho but not GC cells.

thymidine kinase


Input: We report on a case of a 43-old-male with a bronchogenic cyst in the distal esophagus, which was misdiagnosed as a malignant esophageal tumor based on preoperative imaging and high levels of the tumor markers CA 19-9 and CA 125.

CA 19-9

CA 125


Input: Oscillatory flow is reestablished in the model at the capillary-cerebrospinal fluid and capillary-venous interfaces.


Input: This substrate was cleaved efficiently in trans by protease 3C derived from another recombinant vaccinia virus expressing a 3C precursor protein.

protease 3C

3C precursor protein


Input: Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.

Human and murine cytotoxic T lymphocyte serine proteases


Input: The human Fc gamma receptor gene Fc gamma RIIA is expressed in platelets, neutrophils, monocytes and macrophages.

human Fc gamma receptor gene Fc gamma RIIA


Input: Like the nuclear envelope, the intranuclear double membrane lamellae enclosed a defined cisterna that was interrupted by pores but, unlike the nuclear envelope pores, they lacked NPCs.


Input: Regulation of the human stress response gene GADD153 expression: role of ETS1 and FLI-1 gene products.

human stress response gene GADD153

FLI-1 gene products


Input: On days 7, 21, and 35 postinoculation (PI), all birds received sheep erythrocytes intravenously.


Input: The higher level of calories was attained by an increased intake of carbohydrates.


Input: However, it is now suggested that the use of more slowly digested starchy foods may have positive health benefits.


Input: Each receptor must therefore engage a unique subset of the available signaling elements--at least partly through the selection of proteins with src-homology 2 domains (SH2 proteins).

src-homology 2 domains

SH2 proteins


Input: Hence, it is perhaps not necessary to perform spinal puncture if the only purpose is to determine the CSF/serum ratio.


Input: NSAIDS and the microcirculation of the stomach.


Input: Highly significant similarities were detected between the N-terminal region of P30 and those of GENA [the product of another unidentified gene (geneA) located upstream of the aceEF-lpd operon], and GNTR (a putative transcriptional repressor of the gluconate operon of Bacillus subtilis).

GENA

geneA

aceEF

lpd

GNTR

gluconate operon


Input: Promoting fat utilisation by reducing the carbohydrate-fat ratio of the TPN reduces free radical activity to a similar extent as fat exclusion.


Input: It is postulated that the synthesis of the peptidoglycan layer was affected by the antimetabolites since the morphological effects were strikingly similar to those caused by treatment of E. cloacae with disodium edetate plus lysozyme.

lysozyme


Input: The selective 5-HT2 receptor blocker ketanserin was found to reduce maximal urethral pressures in healthy females by about 40% without reducing blood pressure.

5-HT2 receptor


Input: RESULTS: Of 10, 709, 701 chemistry specimens submitted to the participating laboratories during the data collection period, 37, 208 (0. 35%) were rejected prior to testing.


Input: Interestingly, VDR was able to bind to VDREs with high affinity and to fully activate transcription in intact yeast cells in the presence of the retinoid X receptor (RXR).

VDR

retinoid X receptor

RXR


Input: The newly identified repressor element is a rare example of a naturally occurring perfect palindromic binding motif for the NF-kappa B/Rel family of transcription factors.

NF-kappa B

Rel


Input: UV-cross-linking studies suggested that these two complexes represent one and two molecules of ADR1 bound to DNA.


Input: Finally, the conservation of the two residues most sensitive to mutations (Y949 and Y953) in TM11, and in the homologous TM5, of all mammalian P-gps and also in other ABC transporters, suggests that these residues and domains may play an important role in structural as well as mechanistic aspects common to this family of proteins.

mammalian P-gps

ABC transporters


Input: SF1/mBBP utilizes a " maxi-K homology " (maxi-KH) domain for recognition of the single-stranded BPS and requires a cooperative interaction with splicing factor U2AF65 bound to an adjacent polypyrimidine tract (PPT) for high-affinity binding.

mBBP

" maxi-K homology "

maxi-KH


Input: The in vivo response of the PacC-like decamers to external pH was dependent on the status of the pH-regulated activator YlRim101p, which is homologous to the A. nidulans PacC regulator.

PacC-like decamers

PacC


Input: Spongiosa regeneration in the millipore chamber


Input: MTX therapy decreased Ga-67 uptake in liver, tumor, and muscle.


Input: Each of these materials were placed by means of three different placement techniques (Bulk pack, Horizontal layering and Vertical layering) into class II cavities in extracted human molars.


Input: In contrast, the sequences essential for the transcription of EFT1 were localized to the region between the start ATG and the stop codon of the VPS17 gene that terminates 267 nt upstream on the same strand.

VPS17 gene


Input: No transactivation of the ovalbumin promoter (pLovTATA) template control was observed.

ovalbumin promoter

pLovTATA


Input: Removal of cyclin-dependant kinases (cdks) or cdk2 from these extracts using affinity matrices severely inhibits initiation of S phase.

cyclin-dependant kinases

cdks


Input: Consistent with this hypothesis, stimulation of A (2A)-R or PKA enhanced nuclear aPKC activity.

A (2A)-R

PKA

nuclear aPKC


Input: Foreign DNA inserts contained within the fowlpox virus sequence were transferred to the viral genome by homologous recombination occurring in cells infected with a fowlpox virus temperature-sensitive mutant and transfected with both wild-type viral DNA and plasmid DNA.


Input: JCAHO to use ORYX data to detect sentinel events.


Input: Comparisons of the efficacy of benazepril and hydrochlorothiazide alone and in combination have shown that benazepril 20 mg once daily is as effective as or more effective in lowering diastolic blood pressure than hydrochlorothiazide 25 mg once daily and that the combination of benazepril 20 mg and hydrochlorothiazide 25 mg has a possibly synergistic effect on diastolic blood pressure.


Input: Carcinoma-related protein production may have played a role in the development of the observed renal lesions.

Carcinoma-related protein


Input: METHODS: The study population included 70 patients with acute coronary syndromes (14 with recent acute myocardial infarction and 56 with unstable angina pectoris), 105 patients with stable angina pectoris, and 75 control subjects.


Input: Single amino acid substitutions were shown to result from the mutations pdr1-2 (M308I), pdr1-3 (F815S), pdr1-6 (K302Q), pdr1-7 (P298A) and pdr1-8 (L1036 W), whereas the intragenic suppressor mutant pdr1-100 is deleted for the two amino acids L537 and A538.


Input: However, no statistical difference in the Ca/P ratio, carbon concentration and surface energy were observed with different heat treatments.


Input: These motions were found in the N-and C-terminal tails, in segment 33-35 which forms the turn between beta-strands S1 and S2, and residues 47-52 located in a long loop preceding strand S3.


Input: Enterobius vermicularis eggs were demonstrated during microscopic examination of a smear taken from the posterior fornix of the vagina.


Input: Differentiation of porcine mycoplasma strains by means of a simple paper chromatography test.


Input: D., Hughes, F.


Input: We further showed a significant repression of promoter activity (> 40 fold) by E2-2 (lacking the amino acid sequence RSRS) when the E47 reporter construct, containing a hexameric E-box site, was used.

E47 reporter construct


Input: Sequence analysis of AEBP2 cDNA revealed that it encodes a protein containing three Gli-Kruppel (Cys2-His2)-type zinc fingers.

AEBP2 cDNA

Gli

Kruppel


Input: METHODS: The prevalence of haemagglutination inhibiting (HI) antibodies to JE virus (JEV), West Nile virus (WNV) and dengue-2 virus (DEN-2) was detected by HI test and IgM antibody capture ELISA (MAC ELISA) was performed to determine recent infections with JE virus.

haemagglutination inhibiting (HI) antibodies

IgM antibody


Input: To elucidate the mechanism of these hormonal effects, we have studied the regulatory regions of the PFK-2 gene in transfection experiments.

PFK-2 gene


Input: Tryptophan induction prevents Rho-dependent transcription termination in the leader region of the operon.

Rho


Input: An in vitro Raf-1 kinase assay, however, failed to detect LPS-induced Raf-1 kinase activity in RAW 264. 7 cells, suggesting that in RAW 264. 7 cells, Raf-1 kinase is not an activating component of the LPS signaling pathway regulating MAPK activity or sIL-1Ra promoter activity.

Raf-1 kinase

Raf-1 kinase

Raf-1 kinase

MAPK

sIL-1Ra promoter


Input: Subjects were 73 male and female employees of the Xerox Corporation joining a newly developed health fitness program.


Input: The LT-beta gene is expressed in lymphoid cells and organs, but little is known about its inducible regulation.

LT-beta gene


Input: Dose-dependent pharmacokinetics: emphasis on phase I metabolism.


Input: There were no differences in the incidence of fractured zonas.


Input: Our Northern and Southern blot analyses of meningiomas clearly suggest the CLH-22 gene may be involved in the tumor development and can be considered as a candidate for a tumor suppressor.

CLH-22 gene


Input: The difference between the results in the high dose AHLG and in the control group was significant (p less than 0. 05).

AHLG


Input: The stress/BHV-1 model resulted in a mild respiratory infection in all calves with no difference observed between treatment groups.


Input: Cytomegalovirus infection--modern diagnosis


Input: Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.

human multidrug resistance (MDR1) gene

P-glycoproteins


Input: The pepI gene was overexpressed in Escherichia coli.

pepI gene


Input: Deep bite CL II Div.


Input: Negative modulation of alpha1 (I) procollagen gene expression in human skin fibroblasts: transcriptional inhibition by interferon-gamma.

alpha1 (I) procollagen gene

interferon-gamma


Input: Yet IL-2 and IFN-gamma production are independently regulated, as demonstrated by their differential expression in certain T cell subsets, suggesting that the regulatory elements in these two genes must differ.

IFN-gamma


Input: In summary, FGFR3 signaling pathway utilizes two GRB2-containing complexes; Shc. GRB2. Sos and 80K-H. pp66. GRB2. Sos; these two complexes may alternatively link FGFG3 to mitogen-activated protein kinase.

GRB2-containing complexes

Shc

Sos

Sos

mitogen-activated protein kinase


Input: Resistance to Mup was classified as low (minimal inhibitory concentration [MIC] > or = 8 microg/mL) or high (MIC > or = 512 microg/mL) degree.


Input: STUDY DESIGN: Retrospective review.


Input: One had a 48-hour cycle and the other a 24-hour cycle.


Input: 1 The effects of high doses of piretanide, a new diuretic agent chemically related to frusemide and bumetanide were evaluated in twelve patients with severe chronic renal insufficiency (creatinine clearance below 25 ml/min).


Input: S1 nuclease protection mapping and primer extension analysis allowed us to propose that the A residue located 19 bp upstream from the translation initiation codon is the site of transcription initiation.

S1 nuclease


Input: Various stimuli inactivate IkappaB alpha by triggering phosphorylation of the N-terminal residues Ser32 and Ser36.

IkappaB alpha


Input: A mouse brain cDNA library in lambdagt11 was screened for this association, and two positive clones encoding tyrosine phosphatase SH-PTP2 were isolated.

tyrosine phosphatase SH-PTP2


Input: Intensive therapy of viral hepatitis


Input: Adjusting a steady-state warfarin dose depends on the measured INR values and clinical factors: the dose does not need to be adjusted for a single INR that is slightly out of range, and most changes should alter the total weekly dose by 5% to 20%.


Input: Successful resolution of progressive multifocal leukoencephalopathy after combination therapy with cidofovir and cytosine arabinoside.


Input: The DFGF-R protein may thus participate in receiving spatial cues that guide tracheal cell outgrowth.

DFGF-R protein


Input: FTF (Joint Council of Civil Servants and Functionaries): clarification about membership in the main organizations


Input: The differences in binding (Kdapp), incorporation, and extension kinetics of 8-oxo-dGTP compared to normal dNTP incorporation at template 8-oxo-G adducts indicate that polymerase fidelity does not depend solely upon the overall geometry of Watson-Crick base pairs and reflects the asymmetry of the enzyme active site.


Input: Retroviral vector producer cell populations and cell clones were established for each chLTR vector, and all were capable of yielding high vector titers (> 10 (5) G418R cfu/ml on NIH-3T3).

chLTR


Input: None of these patients developed clinical events before disappearance of the phospholipid-dependent inhibitors of coagulation.


Input: A high titer of anti-HBc, thus suggested to be an indicator of persistent hepatitis B virus infection, was found rarely in seronegative patients with chronic hepatitis, non-alcoholic cirrhosis, or alcoholic liver diseases.

anti-HBc


Input: Using beta 1-AR-luciferase reporter recombinants, we have previously determined that important beta 1-AR genetic elements controlling expression within the C6 glioma cell line are contained within the region-396 to-299, relative to the translational start site.

beta 1-AR

luciferase

beta 1-AR


Input: It is not well known that giant cell arteritis can cause fatal complications due to rupture of aortic aneurysms or cerebral and myocardial infarctions.


Input: Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1.

histone deacetylase

ETS domain transcription factor Elk-1


Input: By screening a human testis cDNA library with a probe containing the mouse PEA3 ETS domain, we isolated a 2. 2 kb clone containing a 510 AA open reading frame.

mouse PEA3 ETS


Input: It is also affected by the HAP2/3/4 transcription factor complex and by SNF1 and SSN6.

HAP2/3/4 transcription factor complex


Input: The gene is predicted to encode an 880-amino-acid protein which contains two C2H2 zinc fingers, a nuclear localization sequence and two transcriptional activation domains.


Input: These results indicate that H-2RIIBP (i) is a member of the superfamily of nuclear hormone receptors and (ii) may regulate not only MHC class I genes but also genes containing the ERE and related sequences.

nuclear hormone receptors

MHC class I genes


Input: Relaxant effect of prostaglandin E1 (PGE1) and papaverine (PAP) were measured in strips of corpus cavernosum smooth muscle taken from a healthy control group of men (A; n = 5), from arteriogenically impotent men (B; n = 6) and from additionally diabetic impotent men (C; n = 5) with venous leakage.


Input: The sensitivity of central dopamine receptors was assessed with the growth hormone response to apomorphine application.

central dopamine receptors

growth hormone


Input: Pathogenesis of fever.


Input: The occurrence of the different types of TCRB rearrangement patterns has implications for PCR-based clonality assessment and for PCR-based detection of minimal residual disease via TCRB gene analysis.

TCRB

TCRB gene


Input: In many other contractile protein gene families, genes encoding cardiac isoforms are expressed early in skeletal muscle development and are later repressed.


Input: The NH2-terminal fragments were tested for susceptibility to modification with Nalpha-(3-maleimidylpropionyl) biocytin, which attaches a biotin group to cysteine sulfhydryls.


Input: Directional growth of a smectic-A-smectic-B interface lying along a forbidden orientation.


Input: METHODS: We performed nasal mupirocin treatment on 10 infants who were MRSA-positive either in the nose or the pharynx and evaluated the effect of mupirocin on the eradication of MRSA.


Input: TOM1 encodes a member of the hect-domain-containing E3 ubiquitin-protein ligase family that is required for growth at elevated temperatures.

hect

E3 ubiquitin-protein ligase


Input: Purified preparations of all four AGT mutants showed an approximately similar degree (74-120-fold) of reduction in the rate of reaction with O6-benzylguanine.


Input: These results demonstrate that m2 receptors couple to both G alpha i2 and G alpha i3 in vivo and that this interaction is integral to both positive and negative regulatory pathways leading to activation of PLC and desensitization of receptor signaling.

m2 receptors

G alpha i2

G alpha i3

PLC


Input: This is the first clinical case report of NIHF due to fetal Kasabach-Merritt syndrome that was prenatally diagnosed by sonography, computerized tomography, and percutaneous umbilical blood sampling.


Input: The cholesterol 7alpha-hydroxylase gene (CYP7A) is transcriptionally regulated by a number of factors, including hormones, bile acids, and diurnal rhythm.

cholesterol 7alpha-hydroxylase gene


Input: Restriction mapping showed that the two recombinant plasmids shared an EcoRI fragment of 8. 9 kb.

EcoRI fragment


Input: Two mutants, mapping at the HindIII site (between the consensus sequences) of the pSC101 tetA promoter, were studied: MA2 corresponds to a 4 bp deletion between positions-12 and-15; B30 bears a 44 bp insertion C (TA) 21 G at the HindIII site.

HindIII site

pSC101 tetA promoter

HindIII site


Input: Meq/c-Jun heterodimers bind to an AP1-like sequence in the meq promoter region with an affinity much greater than that of Meq/Meq or c-Jun/c-Jun homodimers.

Meq

c-Jun

AP1-like sequence

meq promoter region

Meq

Meq

c-Jun

c-Jun


Input: Infra-red spectroscopy of tissues in the 700-400 cm-1 region.


Input: Although no detectable phenotypes are associated with a disruption allele of ABP1, mutations that create a requirement for this protein have now been isolated in the previously identified gene SAC6 and in two new genes, SLA1 and SLA2.

gene SAC6


Input: Comparison of bioreactive and immunoreactive gastrin.

gastrin


Input: The claustrocortical connection was investigated in 13 cats with selective injections of 30% HRP in the three subdivisions of the auditory cortex. (ABSTRACT TRUNCATED AT 400 WORDS)


Input: The authors report a case of a painful wrist related to a " Manieux muscle " of the dorsal aspect of the hand.


Input: A significant reduction in total cellular p27 protein levels and a moderate reduction in p27 mRNA are observed, but no changes in Cdk regulatory kinases and phosphatases occur.

p27 protein

p27 mRNA

Cdk


Input: This result, together with the fact that unrearranged V kappa genes are transcriptionally silent, suggests that structural features of both the V kappa and C kappa loci contribute to the overall transcriptional efficiency of a rearranged V kappa-C kappa gene.

unrearranged V kappa genes

V kappa

C kappa loci

rearranged V kappa-C kappa gene


Input: Level II mosaicism occurred in 0. 9 per cent of CVS mesenchyme and 1. 5 per cent of amniotic fluid cultures and in general was not perceived to be of sufficient concern to warrant cytogenetic follow-up studies.


Input: Measures of sedation, BIS, deltaBIS (absolute change of BIS after a painful stimulus), memory, and drug concentration were obtained at each target drug concentration.


Input: There are three types of problems: problems arising before the drug enters the body (solubilization, stabilization and improved acceptability); problems associated with the penetration and fate of the drug in the body (absorption, barrier crossing, duration of action); problems relating to the therapeutic target (selective local delivery).


Input: The structure elucidation of the iridoid compounds 2 and 3 are discussed in detail.


Input: Characterization of trinucleotide-and tandem repeat-containing transcripts obtained from human spinal cord cDNA library by high-density filter hybridization.


Input: CONCLUSION: Urbanisation is associated with an increase in the prevalence rates of some risk behaviours.


Input: The authors emphasize absence of specific signs of vagal involvement, importance for diagnosis of surgical extirpation, and mildness of post operative course.


Input: Growth factors promote cell survival through phosphorylation of Bad, resulting in its dissociation from Bcl-2 and Bcl-x (L) and its association with 14-3-3tau.

Bad

Bcl-x (L)


Input: Both in the Federal Republic of Germany and in some neighbouring countries the epizootic situation of Aujeszky' s disease has been unsatisfactory for a long time, especially in areas with a high pig density.


Input: The sensitivity of 99mTc-IgG scintigraphy ranged between 71% and 100%.

IgG


Input: Acad.


Input: Aggravation of peripheral-blood cytopenia during the first weeks and hypocellularity of bone-marrow aspirates at the end of therapy suggest that low-dose Ara C exerts its main activity by suppression of leukaemic growth, rather than by induction of differentiation in malignant cells.


Input: Those participating in this investigation (65 centers = 79%) received a series of computer disks containing 50 99mTc-DMSA studies.


Input: Probiotics, prebiotics, vaccination, and acidification of drinking water were assessed as means of reducing Salmonella.


Input: Mutation of this threonine to isoleucine had no observable effect on either nuclear localization of E1 or DNA replication of the intact viral genome.


Input: The inhibition of monoamine oxidase (MAO) by tranylcypromine was studied in 6 healthy volunteers given increasing doses of 10, 15, 20 and 25 mg/day over a 4-week period.

monoamine oxidase

MAO


Input: Myocardial technetium-99m-teboroxime uptake during adenosine-induced hyperemia in dogs with either a critical or mild coronary stenosis: comparison to thallium-201 and regional blood flow.


Input: Both atracurium 1-100 mumol litre-1 and laudanosine 1-50 mumol litre-1 enhanced the release of 3H-NA evoked by field stimulation (2 Hz, 24 stimuli), but did not affect resting release.


Input: The recovery of xanthomegnin added to corn samples at levels of 0. 75--9. 6 mg/kg averaged 41% with a coefficient of variation of 25%.


Input: Because of the data, we suggest that LAC9 contacts positions 6, 7, and 8, both plus and minus, of the UAS, which are separated by more than one turn of the DNA helix, and twists part way around the DNA, thus protecting the broad region of the minor groove between the major-groove contacts.


Input: Istanbul, Turkey.


Input: After Northern blot hybridization, two Cx31 transcripts of 2. 2 and 1. 8 kb were detected in total RNA of the human keratinocyte cell line HaCaT and two transcripts of 2. 2 and 1. 9 kb in total RNA of E6/E7 transfected human keratinocytes (HEK cells).

Cx31 transcripts of 2. 2 and 1. 8 kb


Input: While differential expression of the two transcripts was not found, the promoter controlling LT1/LT2 transcription is regulated in a cell cycle-dependent manner.


Input: SYC1 (suppressor of yeast cbf5-1) was identified as a multicopy suppressor of cbf5-1 and subsequently was found to be identical to RRN3, an RNA polymerase I transcription factor.

suppressor of yeast cbf5-1

RNA polymerase I transcription factor


Input: Developmental regulation of expression of the malate synthase gene in transgenic plants.

malate synthase gene


Input: All three SSV-transformed cells secreted v-sis gene product (p44). p44 was secreted but remained tightly associated with the cell surface.

v-sis gene product


Input: We also identified a DNA fragment, 10. 7 kbp upstream from the first coding exon of human aFGF, whose sequence is conserved in both the primate and rodent genomes.

human aFGF


Input: In this respect, the promoter structure of COX genes resemble those of many house-keeping genes.

COX genes


Input: The predicted amino acid sequence of the FlaB2 polypeptide was 92% identical to that of T. pallidum FlaB2, with a 76% identity at the nucleotide level.

FlaB2 polypeptide

T. pallidum FlaB2


Input: These data demonstrate that CCTalpha can be regulated by lipids by two independent domains: (i) the three amphipathic alpha-helical repeats that interact with both neutral and anionic lipid mixtures and (ii) the last 57 residues that interact with anionic lipids.

CCTalpha


Input: Ion-Bernstein-wave heating and improved confinement in the Alcator C tokamak.


Input: Of 3841 serum samples from sows received from the Tennessee State Diagnostic Laboratory in 1991-1992, 1130 were positive for Toxoplasma gondii antibody.

Toxoplasma gondii antibody


Input: Morphometry of the intestine of the pig.


Input: The subjects were started on indomethacin 25 mg thrice daily.


Input: Human parvovirus B19 gene expression from the viral p6 promoter (B19p6) is restricted to primary human hematopoietic cells undergoing erythroid differentiation.

Human parvovirus B19 gene

viral p6 promoter


Input: To further study the role of tTG in liver disease, we initiated investigations into the effect of a proinflammatory mediator, tumor necrosis factor (TNF)-alpha, on tTG activity in cultured liver cells.

tTG

tumor necrosis factor (TNF)-alpha

tTG


Input: The atopic disposition, indicated by positive skin reactions and IgE antibody titers etc., and the bronchial reactivity to inhaled acetylcholine were examined on the following three groups: (1) 20 young adults with a history of childhood asthma who have been symptom-free for more than 4 yr; (2) 20 current asthmatics, and (3) 20 healthy young adults.

IgE


Input: Continuous arterial blood sampling method based on the microsphere model was used as a quantitative rCBF measurement.


Input: Members of the steroid/hormone nuclear receptor superfamily regulate target gene transcription via recognition and association with specific cis-acting sequences of DNA, called hormone response elements (HREs).

steroid/hormone nuclear receptor superfamily


Input: Thomas, S. S.


Input: In addition to these cases, patients w with high Loa microfilaremia also developed milder neurologic manifestations causing functional impairment lasting for at least one week after treatment.


Input: The patient demographics (means +/-standard deviations) were as follows: age, 57 +/-12 years; sex, nine males and three females; APACHE II score, 15 +/-3; diagnosis, 9 of 12 patients with pneumonia.


Input: Patients with binocular pregeniculate visual loss, patients with balanced binocular pregeniculate loss without RAPD, and patients with monocular pregeniculate visual loss had significantly larger pupils than age-matched controls.


Input: In contrast, corticotropin releasing factor (CRF), injected centrally produces a suppression of punished and non-punished responding in the conflict test consistent with its hypothesized role in mediating behavioral responses to stress.

corticotropin releasing factor

CRF


Input: Analysis of replicative intermediates shows that plasmid YRp7, which contains the chromosomal replicator ARS1, initiates bidirectional replication in a 100 bp region within the sequence required for autonomous replication in vivo.


Input: Tag expression induced apoptosis in mammary epithelial cells during late pregnancy.

Tag


Input: Concentrations of Co, Cu, Fe, Hg, Mn, Sb, Se and Zn in IAEA milk (dry) standard A-11 were re-evaluated with the help of instrumental and radiochemical neutron activation analysis (NAA).


Input: Here we show that these sequences are essential for processing of U18 and snR38 snoRNAs and that they compensate for the lack of a canonical terminal stem.

snR38 snoRNAs


Input: In serum-starved NIH 3T3 cells, v-raf increased mdr1 promoter activity approximately 10-fold compared to a v-raf frame-shift control.

v-raf

mdr1 promoter

v-raf


Input: An insertion sequence element (IS1170) was identified upstream of the nimC gene.

nimC gene


Input: Two genes (ptsI and ptsA) that encode homologues of the energy coupling Enzyme I of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system (PTS) have previously been identified on the Escherichia coli chromosome.

ptsI

ptsA

Enzyme I

phosphoenolpyruvate-dependent sugar-transporting phosphotransferase


Input: We show that the upstream region of the beta-MyHC gene (-5518 to-2490 relative to the transcriptional start site) directed high levels of transcriptional activity only when stably integrated, but not when expressed extrachromosomally in transient assays.

beta-MyHC gene


Input: Although the cDNAs of HMG-14 and HMG-17 do not cross-hybridize, they have several similar structural features: the open reading frame comprises only 23% of the transcripts, the 5'-untranslated region is extremely GC rich whereas the 3'-untranslated region is unusually long and AT rich.


Input: A minimal pheromone induction domain, delineated as residues 301 to 335 of Ste12p, is dependent on the pheromone mitogen-activated protein (MAP) kinase pathway for induction activity.

mitogen-activated protein (MAP) kinase


Input: The IFNAR chain interacts with both IFN-alpha 2 and IFN-beta, as demonstrated by cross-linking.

IFNAR chain

IFN-alpha 2

IFN-beta


Input: To assess the effect on thrombus growth, we determined the accretion of 125I-labeled fibrinogen onto autologous non-radioactive thrombi preformed in the jugular veins of rabbits.

fibrinogen


Input: In the other two cases, fluoxetine adjunct produced benefits with no additional side effects.


Input: This radiolabeled, 900-bp amplicon was used as a hybridization probe to screen a cDNA library constructed from poly (A) (+) RNA isolated from induced Taxus cells, from which a full-length transacetylase sequence was obtained.


Input: Similarly, TAM-67 reverted the morphology of the AdoMetDC-antisense expressors.

AdoMetDC-antisense expressors


Input: For the second phase, it was 12. 5 wk for RIR and 10 for WL males, whereas it was 5 wk for RIR and 6 for WL females.


Input: TFEC RNA is found in many tissues of adult rats, but the relative concentrations of TFEC and TFE3 RNAs vary considerably in these different tissues.

TFEC RNA

TFEC

TFE3 RNAs


Input: RESULTS: Three patients did not tolerate PPI medication and were managed by treatment with type 2 histamine (H2) blockers.


Input: VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase.

VLA-4 integrin

mitogen-activated protein kinase


Input: Diethyldithiocarbamate and amphetamine stereotype behavior.


Input: This result, together with the fact that unrearranged V kappa genes are transcriptionally silent, suggests that structural features of both the V kappa and C kappa loci contribute to the overall transcriptional efficiency of a rearranged V kappa-C kappa gene.

unrearranged V kappa genes

V kappa

C kappa loci

V kappa

C kappa


Input: Oct-1 is a ubiquitously expressed regulatory gene of the POU domain family.

POU domain family


Input: Both RNA14 and RNA15 wild-type genes, when cloned on a multicopy plasmid, are able to suppress the temperature-sensitive phenotype of strains bearing either the rna14 or the rna15 mutation, suggesting that the encoded proteins could interact with each other.

RNA15 wild-type genes

rna15 mutation


Input: Recent studies have concentrated on the methods of preparation of coffee, which vary from country to country.


Input: In addition, while GCN1 is required in vivo for phosphorylation of eIF-2 alpha by GCN2, cell extracts from gcn1 delta strains contained wild-type levels of GCN2 eIF-2 alpha-kinase activity.

eIF-2 alpha

gcn1 delta

GCN2 eIF-2 alpha


Input: Seven patients were without a syndromic diagnosis.


Input: Experimental production of a syndrome analogous to hydramnios in the rat fetus


Input: The phP1 mutation was induced by insertion of a 1. 2-kb P element into the 5' transcribed nontranslated region of the proximal polyhomeotic gene.

P element

polyhomeotic gene


Input: By contrast, clonidine (1 micrograms/kg) elicited an immediate and prolonged fall in blood pressure and heart rate when given into the vertebral artery, but not intravenously.


Input: Forty-eight pregnant adult and 122 fetal guinea pigs were sacrificed at intervals throughout gestation and the carcasses analyzed for a variety of growth parameters.


Input: To investigate the in vivo role of this chimeric bZIP protein in oncogenic transformation, its expression was directed to the lymphoid compartments of transgenic mice.

chimeric bZIP protein


Input: The MALDI-TOF experiment, however, proved to be superior to the GC experiment, particularly with regard to baseline resolution of unsaturated acids.


Input: The mean serum CDT increased from 8. 5 (SD 2. 2) U/l to 16. 6 (SD 7. 2) U/l (P < 0. 001).


Input: In female toads, Bufo bufo, feeding at different rates, the uncorrected value of n was 0. 44, when metabolism and growth were expressed as kJ kJ-1.


Input: In contrast, vRel lacks a strong C-terminal gene activation function, since a LexA fusion protein containing C-terminal vRel sequences alone only weakly activated transcription.

vRel

LexA fusion protein

C-terminal vRel sequences


Input: Our study reveals a consequence of adhesion receptor-mediated signaling in T cells, which is potentially important in the regulation of T cell activation, including production of cytokines and expression of proto-oncogenes, many of which are controlled through 3' AU-rich elements.


Input: Assessment of ammonia and urea blood content in metabolic acid-base disorders in white rats.


Input: 3-5-fold increases in EGF receptor but not p185 (neu) tyrosine phosphorylation occur following Gi-coupled receptor stimulation.

EGF receptor

neu

Gi-coupled receptor


Input: So it is sometimes more convenient to use the back Radon transform R-1 and then to correct the result, taking into account attenuation.


Input: Immune and clinical impact of Lactobacillus acidophilus on asthma.


Input: These results indicate that (1) RXR-TR heterodimers play a role in basal transactivation and T3 suppression of negatively regulated genes, and (2) RXRs increase the dominant negative effect of some mutant TRs on specific negative TREs.

RXR

TR

RXRs

TRs


Input: Injections of PD solutions with 13. 6, 22. 7, and 38. 6 g/liter of glucose reduced the ingestion of sucrose by 12. 4%, 23. 6% and 36. 1%, respectively, but did not affect the ingestion of protein.


Input: To examine the functional relationship between distinct cis-active elements within the distal enhancer region of the rat PRL gene, we have used deletional and mutational analysis of that region in transient transfection studies in GH3 pituitary tumor cells.

rat PRL gene


Input: While there is growing evidence that perception and imagery share common neural substrates, the fact that D. F. shows intact visual imagery in the face of a massive perceptual deficit in form vision challenges recent suggestions that these two psychological processes share common input pathways in early vision.


Input: Site-directed mutagenesis of the conserved cysteine residue (tom1C3235A) in the hect-domain, supposed to be necessary for thioester-bond formation with ubiquitin, abolished the gene function.

hect-domain

ubiquitin


Input: The Seldinger technique for difficult transurethral catheterization: a gentle alternative to suprapubic puncture (Br J Surg 2000; 87: 1729-30).


Input: Gingival retraction for class V restorations.


Input: The amino acid sequence of the protein encoded by MSK1 is homologous to yeast cytoplasmic lysyl-tRNA synthetase and to the product of the herC gene, which has recently been suggested to code for the Escherichia coli enzyme.

yeast cytoplasmic lysyl-tRNA synthetase

herC gene


Input: In contrast to p62 (dok), DOKL lacks YxxP motifs in the C terminus and does not bind to Ras GTPase-activating protein (RasGAP) upon phosphorylation.

dok

DOKL

Ras GTPase-activating protein

RasGAP


Input: The presence of chloroquine in saliva from seven healthy volunteers for 21 days after a single 600 mg oral dose of the drug was established by chromatographic and spectroscopic methods.


Input: In vitro binding studies previously showed that NF-kappa B p50 homodimer binds the switch nuclear B-site protein (SNIP) of the S gamma 3 tandem repeat.

NF-kappa B p50

switch nuclear B-site protein

SNIP

S gamma 3 tandem repeat


Input: If, however, myocardial stunning is severe, and it involves large parts of the LV and thus impairs global LV function, it can be reversed with inotropic agents and procedures.


Input: Similarly, interfering with MEKK, which lies upstream of JNK1, using a dominant negative expression vector reduced MMP-9 promoter activity over the same concentration range which repressed the AP-1-thymidine kinase CAT reporter construct.

MEKK

MMP-9 promoter

thymidine kinase CAT


Input: The 7. 2 kb EcoRI fragment of AfMNPV was cloned and the nucleotide sequences of the polyhedrin coding region and its flanking regions were determined.

7. 2 kb EcoRI fragment of AfMNPV

polyhedrin


Input: Joint ultrasonography demonstrating thickening of synoviae and tendons has become a useful non-invasive diagnostic tool, although it is not specific for beta 2-M amyloidosis, and results depend on observer experience.

beta 2-M


Input: Sequence analyses revealed a partial 941 bp cDNA that encoded a 313-amino-acid polypeptide.


Input: Estimating the health care costs of smokers.


Input: Although paclitaxel alone failed to induce p38 MAPK activation, subsequent (but not prior) exposure to PD98059 induced a dramatic increase in p38 MAPK phosphorylation.


Input: The cyclin-dependent kinase Cdk2 associates with cyclins A, D, and E and has been implicated in the control of the G1 to S phase transition in mammals.

cyclin-dependent kinase Cdk2

cyclins A, D, and E


Input: Sequences within the UAS2 element of the ENO2 gene bound a second protein which corresponded to the ABFI (autonomously replicating sequence-binding factor) protein.

ENO2 gene

ABFI

autonomously replicating sequence-binding factor


Input: Videoanalysis confirms the ballistic character of the initial phase of the reaching movement.


Input: Toward this end, we used two cultured colon cancer cell lines; one (RKO) has a transcriptionally activated u-PAR gene, and the other (GEO) overexpresses the receptor only after phorbol ester treatment.

u-PAR gene


Input: Early detection and signs of hepatoangiosarcoma among vinyl chloride workers.


Input: Many retroviruses, including the human and simian immunodeficiency viruses, contain a leucine zipper-like repeat in a highly conserved region of the external domain of the transmembrane (TM) glycoprotein.


Input: Conversion of an NF-kappaB into a GABP binding site is likely to have occurred also during the worldwide spread of HIV-1, as we noticed the same LTR modification in subtype E isolates from Thailand.

NF-kappaB

GABP


Input: Bedbug (Cimex lectularius) samples adult and nymphs either engorged or starved from Central Security Forces sleeping wards, laboratory animal house and control samples from laboratory reared colonies were ground and subjected to ELISA test of hepatitis B surface antigen together with 276 serum samples from the recruits slept in those wards.

hepatitis B surface antigen


Input: Ciprofloxacin attained a peak serum concentration of 1. 2 mg/l and a serum half-life of 34 min.


Input: As usual tests, such as " time " of cephalin are slightly sensible to LMW-Hep, only anti-Xa activity can be used.


Input: Although they are similar to the IL9R gene (approximately 90% identity), none of these copies encodes a functional receptor: none of them contains sequences homologous to the 5' flanking region or exon 1 of the IL9R gene, and the remaining ORFs have been inactivated by various point mutations and deletions.

IL9R gene

IL9R gene


Input: In two patients, a male homosexual and an hemophiliac, thrombocytopenia was associated with AIDS-related complex.


Input: Choline acetyltransferase immunohistochemistry combined with the retrograde transport of horseradish peroxidase showed that the reticular and mediodorsal thalamic nuclei of the cat receive an important input from cholinergic and non-cholinergic neurons of substantia innominata and adjacent structures in the basal forebrain.

Choline acetyltransferase

horseradish peroxidase


Input: Mortality among patients with CAVB is still high and has not declined within the last decade.


Input: We conclude that in the presence of fatty acids in the medium transcription of SPS19 is directly regulated by both Pip2p-Oaf1p and Adr1p.


Input: The purified RAG1 protein overexpressed in E. coli exhibited the expected cleavage activity when combined with RAG2 purified from transfected 293T cells.

RAG1 protein


Input: Serum triglycerides also showed an increase from birth to 6 months of age, but a decrease from 6 months to 1 years of age.


Input: These mutant rps7 leaders were ligated into an aadA expression cassette and transformed into the chloroplast of C. reinhardtii and into E. coli.

mutant rps7


Input: The use of medication is of minor importance in the treatment of flight phobia.


Input: We previously described the upregulation of the MT2 antigen during urodele limb regeneration and characterized the MT2 antigen as a 310-to 325-kDa chondroitin-sulfated glycoprotein with a core protein of 285-300 kDa.

MT2 antigen

MT2 antigen


Input: Southern blot analysis following reverse transcription and PCR showed that B2R is expressed in most mouse tissues, except the liver and spleen, which is consistent with the wide distribution of B2R activity as deduced from pharmacological studies.


Input: The dynamics of N-interaction and N-retention during 3 hr CPB was quantified with autologous In-111 labeled neutrophils (INN) in 4 groups of 20 Yorkshire pigs (28-35 kg, 5 sham; 5 CPB, 1 hr; 5 CPB, 3 hr and 5 CPB with heparinized circuit, 3 hr); anesthetized pigs were injected with INN (500-650 microCi), 30 min before CPB and heparinized, and underwent CPB with a roller pump, a hollow fiber OX (Bentley CM 50, 5. 0 m2) and AF (Bentley AF 025, 0. 25 m2) at 2. 5-3. 6 l/min for 3 hr.


Input: The effect of the negative regulatory element is negated by the viral IE2 protein (L.

viral IE2 protein


Input: Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells.

GATA-binding protein

endothelin-1 gene


Input: John' s wort


Input: In contrast SF, but not GM-CSF or IL-3, induced tyrosine phosphorylation of phospholipase C-gamma (PLC-gamma).

SF

GM-CSF

phospholipase C-gamma

PLC-gamma


Input: Using the interaction-trap assay to identify candidate proteins that bind the cytoplasmic region of the LAR transmembrane protein tyrosine phosphatase (PT-Pase), we isolated a cDNA encoding a 2861-amino acid protein termed Trio that contains three enzyme domains: two functional GEF domains and a protein serine/threonine kinase (PSK) domain.

LAR transmembrane protein tyrosine phosphatase

PT-Pase

Trio

GEF domains

protein serine/threonine kinase

PSK


Input: The role of the putative C2 domain of Nedd4 has not been elucidated.


Input: The effect on FIV LTR promoter activity of progressively deleting these nuclear factor binding sites was examined by linking LTR deletion mutants to the chloramphenicol acetyltransferase (CAT) gene.

FIV LTR promoter

chloramphenicol acetyltransferase

CAT


Input: Additionally, these findings have important implications for the understanding of the mechanisms of HIV-1 latency and reactivation.


Input: Furthermore, we show that Nck-2 is capable of recognizing several key components of growth factor receptor kinase-signaling pathways including EGF receptors, PDGF receptor-beta, and IRS-1.

growth factor receptor kinase

EGF receptors

PDGF receptor-beta


Input: The average mean difference compared with the low and the intermediate calcium group was 11% for the femoral neck, 8-11% for the lumbar spine and 5-6% for total body BMDs.


Input: Although the number of kits has increased, the precision has improved, showing that more robust methods are now employed.


Input: The predicted amino acid sequence contained all consensus regions for S-adenosyl methionine methyltransferases and presented 26% identity with Saccharomyces cerevisiae DHHB-methyltransferase and 38% identity with the rat protein, as well as with a bacterial (Escherichia coli and Salmonella typhimurium) methyltransferase encoded by the UBIG gene.

S-adenosyl methionine methyltransferases

Saccharomyces cerevisiae DHHB-methyltransferase

methyltransferase

UBIG gene


Input: To investigate its transcription, 1. 1 kilobases of the 5'-flanking sequence were fused to a luciferase reporter gene.

luciferase reporter gene


Input: A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.

estrogen receptor


Input: PATIENT (S): Two hundred thirty-eight patients with RPLs, 48 patients with recurrent IVF-ET failure and 179 nonpregnant and 120 pregnant control group women.


Input: The effects of oxalate-containing products on the exposed dentine surface: an SEM investigation.


Input: The cyanobacterial phycobilisome is a large protein complex located on the photosynthetic membrane.

cyanobacterial phycobilisome


Input: Up to 1988, 145 cases had been reported in literature and 32 cases in our country.


Input: Lamivudine therapy for acute hepatitis B infection following peripheral blood stem cell transplantation.


Input: Disorganization scores of the hypertrophy zone and trabecular bone were low, approaching normal (P < 0. 05), for turkey poults fed on diets with phytase supplementation, and tibial abnormality scores were linearly decreased (P < 0. 001) as nP levels increased (zero score is considered normal).

phytase


Input: The collicular labels found after injections within the MST area exhibited their distribution over the deep SC subdivision, whereas they spared all the superficial layers but the deep part of the SO.


Input: Modern aspects of shock-treatment in extensive burns (author' s transl)


Input: UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins.

tumor necrosis factor (TNF) receptor 1

TNF receptor-associated factor-2

Rel proteins


Input: Mapping of the region in KAP-1 required for HP1 interaction showed that amino acid substitutions which abolish HP1 binding in vitro reduce KAP-1 mediated repression in vivo.


Input: However, whether this was associated with spleen removal after adjustment for risk factors was not determined.


Input: Taken together, these data suggest that the Smad3/Smad4 complex has at least two separable nuclear functions: it forms a rapid, yet transient sequence-specific DNA binding complex, and it potentiates AP1-dependent transcriptional activation.


Input: However, one activity binds preferentially to G + C-rich promoters, and another activity appears to bind preferentially to only two of the promoters tested.


Input: The donors of 10 patients were ABO-incompatible, and for five pairs the ABO incompatibility was major.


Input: In treatments R1 and R2, feed quality was restricted by withholding concentrates for 3 and 4. 5 mo, respectively.


Input: The major promoter element of the Xenopus laevis 5S RNA gene is located within the transcribed region of the gene and forms the binding site for the transcription initiation factor TFIIIA.

Xenopus laevis 5S RNA gene

TFIIIA


Input: However, in transient transfection assays, a truncation of as little as 15 Nurr1 COOH-terminal amino acids diminished transcriptional activation of B1A-thymidine kinase-chloramphenicol acetyltransferase reporter.

thymidine kinase

chloramphenicol acetyltransferase


Input: Small cell tumors in children: contribution to the solution of the problem of differential diagnosis with immunohistochemistry and electron microscopy


Input: Four experiments examined the role of the cholinergic projections from the septum and vertical limb nucleus of the diagonal band of Broca (VDB) in acquisition and performance of a conditional visual discrimination.


Input: Deletion of this consensus element from the spo6 promoter abolished the transcription of spo6 + and resulted in a sporulation deficiency.

spo6 promoter

spo6 +


Input: This region does not contain a consensus estrogen response element, and ER binding to this DNA sequence was not observed.

ER


Input: We have previously reported that analgesic doses of morphine accelerate mortality of rats exposed to hemorrhage (Feuerstein and Siren: Circ Shock 19: 293-300, 1986).


Input: Microsporum persicolor, an easily misinterpreted dermatophyt


Input: When they were exposed to intermittent schedules of punishment (fixed-interval [FI] 120 s or FI 300 s), SIB for all but 1 of the participants increased to levels similar to those observed during baseline.


Input: These results suggest that 1a, which also interacts independently with the ER and viral RNA, is a key organizer of RNA replication complex assembly.


Input: Here we examine the population of gammaS transcripts in adult human lens and the structure of the human CRYGS genes.

gammaS transcripts

human CRYGS genes


Input: PKK exists in three discernible forms at steady state: an underphosphorylated form of 100 kDa; a soluble, cytosolic, phosphorylated form of 110 kDa; and a phosphorylated, detergent-insoluble form of 112 kDa.

PKK


Input: The lamina densa was always interrupted by numerous small gaps and in some areas the basement membrane could not be identified over a long distance.


Input: The human CA11 gene appears to be located between the secretor type alpha (1, 2)-fucosyltransferase gene cluster (FUT1-FUT2-FUT2P) and the D-site binding protein gene (DBP) on chromosome 19q13. 3.

human CA11 gene

secretor type alpha (1, 2)-fucosyltransferase gene cluster

D-site binding protein gene

DBP


Input: A score (APACHE II) was calculated to assess the severity of disease.


Input: To determine the role of elevated FAK expression in facilitating epidermal growth factor (EGF)-stimulated human adenocarcinoma (A549) cell motility, antisense oligonucleotides were used to reduce FAK protein expression > 75%.

FAK

epidermal growth factor

EGF

FAK protein


Input: Evaluation of materials and technics in vascular surgery using 111-Indium


Input: Functional importance of a properly folded surface loop covering the catalytic center.


Input: Hypoxia decreased the rate of spontaneous impulse initiation in SA nodal fibers by decreasing the slope of diastolic depolarization.


Input: Radiative corrections to pi l2 decays.


Input: The availability of a commercial program (PCNONLIN) is needed to carry out matrix handling calculations.


Input: The levels of TPAR1 mRNAs were dramatically down-regulated in regenerating rat liver when compared to normal adult liver.

TPAR1 mRNAs


Input: In the postoperative patient with tetralogy of Fallot with symptomatic ventricular arrhythmias, it is concluded that electrophysiologic study is useful in reproducing clinical episodes of VT and in selecting effective antiarrhythmic medication; a small number of patients with ventricular premature complexes alone will have inducible sustained VT during electrophysiologic study; prognosis of these patients may be improved by treatment that results in prevention of VT induction; and in patients with right ventricular hypertension, VT is likely to be refractory to drug treatment.


Input: Hip fracture mortality and prospective payment system.


Input: Primary care programs for the indigent.


Input: In human myxoid liposarcoma, a chromosomal rearrangement leads to fusion of the growth-arresting and DNA-damage-inducible transcription factor CHOP (GADD153) to a peptide fragment encoded by the TLS gene.

CHOP

TLS gene


Input: Categorisation of the different substructures within the sections allows them to be analysed and displayed separately.


Input: Authors present the anatomical variations of the course of the inferior mesenteric artery and its branches in 62 human fetus.


Input: This mechanism seems to be involved in VIP-induced PRL gene regulation.

VIP

PRL gene


Input: The only quantities which were significantly different between appendicitis and a normal appendix were sex, duration of symptoms, anorexia and vomiting.


Input: Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis.

mitogen-activated protein kinase

Rac

Rho

Ras


Input: The survival of patients with a short bowel, even if they need long-term parenteral nutrition, is good.


Input: Unlike these contaminant-responsive T cells, those that are truly specific for natural AChR epitopes appear less heterogeneous and therefore more suitable targets for selective immunotherapy.

AChR epitopes


Input: CONCLUSIONS: This initial experience indicates that there is short-to middle-term efficiency and safety when using GKS to treat MTLE.


Input: A Brassica cDNA clone encoding a bifunctional hydroxymethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase involved in thiamin biosynthesis.

hydroxymethylpyrimidine kinase

thiamin-phosphate pyrophosphorylase


Input: The aims of this study were to examine whether the EORTC (European Organisation for Research and Treatment of Cancer) QLQ-C30 core questionnaire alone could distinguish between two clinically different groups of patients and to design a module, which included relevant patient-defined gastric cancer-specific variables.


Input: The goal of our work was to determine hearing thresholds in patients with hearing impairment due to hereditary motor and sensory neuropathy (HMSN I).


Input: Causal modeling combines theory and research, and because the interpretation of data is possible only within the context of the proposed theory, it offers an important method for advancing the science while maintaining the specificity of the practice.