Input: Among known flea larvae, the genus Anomiopsyllus (Anomiopsyllinae, Anomiopsyllini) is as distinctive in larval form as are the adults.


Input: Here, we have used specific antibody to identify and characterize the SSN6 protein.

SSN6 protein


Input: These latter results showed that the ABFI protein, like the RAP1 protein, bound sequences required for positive as well as negative regulation of gene expression.

ABFI protein

RAP1 protein


Input: Clinical nutrition of adult horses.


Input: The computer-programmed cytocentrifuge is currently most popular.


Input: RNase protection assays reveal that this gene, unr, is transcribed in the same direction as N-ras and that its 3' end is located just 130 base pairs away from the point at which N-ras transcription begins.

RNase

unr

N-ras

N-ras


Input: Isolation of a temperature-sensitive mutant with an altered tRNA nucleotidyltransferase and cloning of the gene encoding tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae.

tRNA nucleotidyltransferase

gene encoding tRNA nucleotidyltransferase in the yeast Saccharomyces cerevisiae


Input: The juxtamembrane region of the insulin receptor (IR) beta-subunit contains an unphosphorylated tyrosyl residue (Tyr960) that is essential for insulin-stimulated tyrosyl phosphorylation of some endogenous substrates and certain biological responses (White, M. F., Livingston, J. N., Backer, J. M., Lauris, V., Dull, T. J., Ullrich, A., and Kahn, C. R.

insulin receptor (IR) beta-subunit

insulin


Input: This gene joins the group of genes whose members are rapidly transcribed in response to insulin and other mitogens.

insulin


Input: The 3' region, GA2, is necessary for maximal expression.


Input: Pups placed into the novel environment with their mothers exhibited an intermediate level of DA turnover.


Input: The efficacy and safety of a novel percutaneous anaesthetic preparation based on amethocaine has been investigated in the paediatric clinical environment.


Input: Homozygous protein C (PC) deficiency is reported in two siblings (girl and boy) who received their proper diagnoses at the ages of 7 4/12 and 1 3/12 years respectively.

protein C

PC


Input: The grandfather and the granddaughter both had microtia and meatal atresia, whereas the daughter had a normal outer ear except for a narrow meatus and auricular appendages.


Input: Abnormal intrapulmonary shunting (IPS), which was proved in 4 cases by whole-body radionuclide scanning with 99mTc-MAA, is suggested as the major cause of cyanosis in liver cirrhosis.


Input: More generally, Ets1 and Ets2 could regulate transcription of cellular genes.


Input: Within this sequence the MSAS gene was identified as a 5322-bp-long open reading frame coding for a protein of 1774 amino acids and 190, 731 Da molecular mass.

MSAS gene


Input: Horseradish peroxidase as a permeability marker in injured rat caudal and iliac arteries.

Horseradish peroxidase


Input: Standardized gastric wall specimens from the area of grossly healed ulcers were obtained, processed, and evaluated by light microscopy and by transmission electron microscopy.


Input: The effects of coenzyme Q10 (CoQ) and captopril on functional capacity, hemodynamics and survival were studied in 154 rats that recovered after experimental myocardial infarction.


Input: Evidence that therapeutic alterations of a circadian rhythm for gastric emptying response may be possible.


Input: The interrelation of the levels of glucocorticoids and insulin in the blood of irradiated animals

insulin


Input: This last includes tissue O2 transfer (Ft') and mitochondrial O2 utilization (Fm').


Input: Foveating saccades, therefore, can be distinguished from other FEMs on the basis of speed.


Input: Incidence correlated with the grade of oral hygiene und periodontal disease.


Input: Our study shows that the area of Alcoy is a medium MS risk region according to the thesis of Kurzke, although high MS areas may be found, thus confirming that MS distribution in southern Europe is not uniform.


Input: On an antithrombin unit basis, CY 216 and CY 222 were equivalent and more potent than UH.

antithrombin


Input: Chick brain actin depolymerizing factor (ADF) is a 19-kDa protein that severs actin filaments and binds actin monomers.

Chick brain actin depolymerizing factor

ADF

actin filaments

actin monomers


Input: Initial experience with a serotonin agonist.


Input: Comprehensive care of the patient exposed to a human teratogen may also include discussion of prenatal diagnostic procedures and other pregnancy management options.


Input: Primer extension analysis and RNA sequencing demonstrates that the transcription start point of rat ODC mRNA is located 303 nt upstream from the A residue in the start codon.

rat ODC mRNA


Input: For 85Sr, larger-than-expected distribution coefficients were obtained in the desorption experiments, an indication of the irreversible formation of metal-oxyhydroxides during a slow reaction.


Input: Gene constructs possessing the complete tat, rev (tat + rev +) and env genes were transiently expressed in COS-1 cells as precursor SU-TM (gp160), SU. TM (gp120 x 41), and nucleolar rev protein.

complete tat

rev

tat + rev +

env genes

precursor SU-TM

SU. TM

gp120 x 41

nucleolar rev protein


Input: This growth arrest is partly suppressed on minimal medium or under conditions in which the cells are less dependent on mitochondrial metabolism.


Input: Giant pilomatrix carcinoma: report and review of the literature.


Input: Further studies of mandibular movement at initial tooth contact.


Input: Each parent interacted with their 4-or 5-year-old son or daughter in each of two conversations--unstructured (social conversation) and structured (task activity).


Input: Droperidol-induced extrapyramidal symptoms in an adolescent following strabismus surgery.


Input: These results indicate that the cis-regulatory elements required for developmental control of the HaG3-A helianthinin gene are located in a 2. 4 kb upstream region of this gene.

HaG3-A helianthinin gene


Input: The induction by pseudorabies virus of an IL-6 construct containing the IL-6 TATA box and the RNA start site (" initiator " or Inr element) but not the MRE region was also repressed by Dex in the presence of wild-type GR.

IL-6 construct

IL-6 TATA box

wild-type GR


Input: Some mutations affected Dhfr in a qualitative manner, such as by changing the startpoint of one of the major Dhfr transcripts or changing the relative abundance of the two major Dhfr transcripts.

Dhfr

Dhfr transcripts

Dhfr transcripts


Input: The glial cyst wall was lined in part by flattened or cuboidal epithelium.


Input: We conclude that class I cytologic smears with moderate to severe inflammation may be associated with findings of condylomata and cervical dysplasia.


Input: As in mammals, considerable nucleotide diversity was observed at the junctions of the variable, diversity, and joining elements in chicken TCR beta cDNAs.

chicken TCR beta cDNAs


Input: The protooncogene c-myb encodes a nuclear transcription factor that binds to DNA in a sequence-specific manner and transactivates transcription of several viral and cellular genes.

c-myb


Input: Modification by this latter compound was so extensive that the amount of membrane-associated N-myristoylated protein was decreased.


Input: S6 kinase activation requires displacement of this inhibitory segment, which is proposed to occur consequent to its multiple phosphorylation.

S6 kinase


Input: Cerebral flow and resistance showed minor reductions with HD.


Input: Utilization of alternative polyadenylation signals was previously shown to generate two sialophorin mRNAs of 1. 9 and 4. 3 kb, which differ in the length of their 3' untranslated regions.

sialophorin mRNAs of 1. 9 and 4. 3 kb


Input: Presidential address 1990--coming in from the cold.


Input: The Jenkins Activity Survey and the CPI-revised: further evidence of adaptive and maladaptive type A traits.


Input: There was evidence of attenuated regression slopes relating recalled to observed portion sizes for 4 of the 10 food groups; adjusted r2 values for the recalled portion sizes ranged from 0. 02 to 0. 94.


Input: The result suggests that this non-invasive TTD method is easily available and useful in monitoring the intraoperative cardiac output.


Input: The TUP1 gene was isolated in a screen for genes that regulate mating type (V. L.

TUP1 gene


Input: The SUP44 suppressor mutation occurs near a region of the protein that corresponds to the known positions of alterations in E. coli S5 ram mutations.

SUP44 suppressor mutation

E. coli S5 ram mutations


Input: Interestingly, disruption of the VPS34 locus resulted in a temperature-sensitive growth defect, indicating that the VPS34 gene is essential for vegetative growth only at elevated growth temperatures.

VPS34 locus

VPS34 gene


Input: We describe a case of a perinephric abscess treated with amphotericin B and nephrectomy.


Input: This interaction occurs over a wide range of both parameters; for charge density from at least 10 to 800 microC/cm2 and, for charge per phase, from at least 0. 05 to 5. 0 microC per phase.


Input: Perceptions of illness intrusiveness were significantly higher when both muscle cramp and headache symptoms occurred during one or more assessment intervals as compared to when muscle cramps or headaches, only, occurred.


Input: Results have surprisingly revealed the presence of three U14 snRNA-homologous regions positioned within introns 5, 6, and 8 of the mouse cognate hsc70 heat shock gene.

U14 snRNA-homologous regions


Input: 65-kilodalton protein phosphorylated by interleukin 2 stimulation bears two putative actin-binding sites and two calcium-binding sites.

interleukin 2

actin-binding sites


Input: The highly restrained girls had a significantly higher EAT score than the low-restrained girls, and shared with their mothers a susceptibility to the disinhibitory effects of negative mood states on their eating behaviour.


Input: Sequence and genetic organization of a Zymomonas mobilis gene cluster that encodes several enzymes of glucose metabolism.


Input: For this, cDNAs containing the 60K, 87K, 110K and 170K protein coding sequences were each provided with an ATG start codon and the cDNA containing the 60K coding sequence with a TAA stop codon immediately downstream of the coding sequence.


Input: Finally, a complementary footprinting analysis of the upstream region of the constitutively expressed HSC82 gene reveals the presence of three discrete protein complexes.

HSC82 gene


Input: Pathophysiology of bone loss in castrated animals.


Input: Auditory-visual interaction in the generation of saccades in man.


Input: First, each lung was cut into slices, from which primary disectors were sampled systematically with a known sampling fraction.


Input: The upstream promoter is located within the coding sequence of a divergent gene expressing a protein of Mr 39 kDa of unknown function.


Input: Assuming O2 consumption of the isolated skin to be same as in situ, calculations showed that when water PO2 was high (150 mm Hg), about 40% of total cutaneous O2 uptake was consumed by the skin.


Input: MCh infusion caused a concentration-dependent increase in airway resistance at constant QBA.


Input: Plasma concentrations of atracurium and laudanosine were 0. 73-3. 11 micrograms ml-1 and 0. 48-8. 65 micrograms ml-1, respectively; CSF concentration of laudanosine was 70-440 ng ml-1.


Input: Plasma Al was obtained during each baseline and drug course.


Input: The survival in the case of these patients was studied five years later.


Input: The occurrence, maintenance and possible involvement of these repeated sequences, capable of forming stable secondary structures, are discussed in relation to their location in the region of control signals.


Input: IST is not the RNA target (TAR) for Tat trans-activation; however, because it relies entirely on cellular factors for activity, IST may serve to provide abundant RNA targets for Tat trans-activation without a requirement for full-length viral mRNA expression.

IST

Tat

IST

Tat


Input: Genotoxic activity of a tobacco-specific nitrosamine.


Input: The endodontal treatment need has been forming a clinical order of magnitude.


Input: These results may suggest involvement of peripheral enkephalins in pain modulation in patients with episodic cluster headache.


Input: Effects of cisapride on upper-gastrointestinal motility and digestive hormones


Input: Common foot pathologies are heel pain, metatarsalgia, hammertoes and clawtoes, bunions, hallux rigidus, corns and calluses, nail pathologies, arthritis, and neuropathies.


Input: Liver dysfunction in the presence of different adverse reactions presented with a higher activity in the blood serum of indicator liver enzymes and its impaired protein-forming function.


Input: Coenzyme Q10: blood levels and metabolic demand.


Input: The CT characteristics are discussed and the recent literature is reviewed.


Input: Unfortunately, these preservatives may also interfere with microbiological assays used to determine product sterility or bioburden levels.


Input: In 26 patients with angina pectoris, the changes of LVEF, LVESV and PSP/LVESV were more sensitive for the detection of exercise-induced ischemia than the appearance of chest pain and the changes of ECG.


Input: In both groups there were 5 management failure of therapy, so that alternative medication or a cesarean section lead to delivery.


Input: Serum Fibrin Degradation Products (FDP) were determined in 50 oral cancer patients and 50 normal individuals prior to any kind of treatment.

Fibrin Degradation Products

FDP


Input: The uteroglobin promoter contains a noncanonical estrogen responsive element.

uteroglobin promoter


Input: Prostaglandin synthesis inhibitors have been shown to delay healing of bone and this has led to limitations on their use clinically in some situations.


Input: The inspiratory oxygen concentration needed (FiO2) and the Horowitz quotient differed in a highly significant manner beginning on the 1st day after trauma.


Input: The corn and mineral oil emulsions were almost as effective as milk but less effective than sucrose (0. 3M) in stimulating ingestion.


Input: Significance of thin glomerular basement membranes in hematuric children.


Input: Significance of cytokine production and adhesion molecules in malarial immunopathology.


Input: The former procedure is economical but complicated, whereas the latter is simple and labour-saving, but a special ultrafiltration tube is required.


Input: Simple method for determination of the cephalosporin DQ-2556 in biological fluids by high-performance liquid chromatography.


Input: Since one group of adolescents more difficult to influence are those whose parents smoke, parental involvement in smoking prevention may be a powerful enhancer.


Input: Further research is recommended to identify the coping styles associated with the high EE/low EE research classification.


Input: Staining with IF MoAB alone of BAL fluid only seemed to be even more sensitive than silver methenamine staining of BAL, TBB and brushing material.


Input: Ultrastructural and morphometric study of the myeloid parenchyma cells of mice prior and after X-ray exposure


Input: Using an audiotape cassette and headphones the duration of the hallucinations decreased significantly.


Input: The mean change in HbA1, adjusted for the initial value, was-0. 4% in the experimental and + 0. 5% in the control group (p less than 0. 05).


Input: Effect of biliary obstruction and cholangitis on serum SPan-1 level

serum SPan-1


Input: Very good accuracy (r greater than 0. 9) was found when except comparing H * 2 with the other machine and the reference methods, except for MCHCH and basophil count.


Input: The second part of this paper shows some medical applications of these two aspects of NMR, with help of some examples, taken from the literature, according to what is concerned with endocrinology.


Input: Interlimb coordination during fictive locomotion in the thalamic cat.


Input: Antileukoproteinase (ALP) is a low mol wt mucosal secretory protein which, in human tissues, inhibits the activities of the neutral serine lysosomal proteinases elastase and cathepsin-G.

Antileukoproteinase

ALP

serine lysosomal proteinases elastase

cathepsin-G


Input: By introducing a series of deletions in the vimentin promoter, we further restrict these sequences to 30 base pairs, located between 241 and 210 base pairs upstream of the mRNA cap site.

vimentin


Input: In particular, 71 and 69% amino acid sequence similarities were identified with hsp70 of Escherichia coli and Bacillus megaterium, respectively.

hsp70 of Escherichia coli and Bacillus megaterium


Input: All 89 participating household members were anti-HIV seronegative, and 78 who were tested were serum p24 antigen negative.

anti-HIV

serum p24 antigen


Input: To those of us who are not satisfied with the present outlook there is much to be investigated and much to be contributed.


Input: To determine the effects on the pulmonary barrier of several surface active agents, a series of metered dose inhalers (MDIs) was prepared and used to dose aerosolized surfactant to the airways of isolated perfused rat lungs.


Input: The beta chain contains five potential N-linked glycosylation sites, and endoglycosidase digestion suggested that the beta chain contained multiple complex carbohydrate side chains.

endoglycosidase


Input: The therapeutic protocole used at the Gustave Roussy Institute for invasive epithelioma of the uterine cervix rests, for limited forms (T1B-T2 proximal), on combined radiology and surgery.


Input: Thyrotropin-induced expression of a gene for a ribosomal protein related to the trk oncogene.

Thyrotropin

ribosomal protein

trk oncogene


Input: The introns are 1. 6-1. 9 kbp long.


Input: After an initial titration period and adjustment of the therapeutic dose, the individual doses were from 21 to 500 micrograms/24 hrs (mean 160 micrograms/24 hrs).


Input: In the first series of experiments, Sprague-Dawley male rats were implanted unilaterally with guide cannulas aimed at the lateral ventricle.


Input: Use of Selenastrum capricornutum and Microfeast as food for Daphnia pulex.


Input: The persistence of members of the prostigmatid families Tydeidae, Nanorchestidae and Tarsonemidae in the moisture-deficient 90%-concentration treatments supports previous evidence of adaptations to low-water-content habitats.


Input: To define the mechanism responsible for the loss of transcription elongation blockage and resulting c-myc deregulation in Burkitt' s lymphoma, we analyzed transcription patterns after transfer of normal and Burkitt' s lymphoma c-myc alleles into murine cells and Xenopus oocyte germinal vesicles.

c-myc

c-myc


Input: From an RNK-16 lambda-gt11 library, we have isolated and sequenced a novel cDNA rat NK cell protease 1 (RNKP-1) that has characteristics unique to serine proteases.

rat NK cell protease 1

serine proteases


Input: The induction of RNKP-1 expression in the Con A-cultured spleen cells is accompanied by increases in both NK and lymphokine-activated killer lymphocyte activities.

Con A


Input: The paper is concerned with the data on change in the blood level of ACTH, STH, TSH, cortisol, T3, insulin, C-peptide during a 25-minute session of respiration using a gaseous hypoxic mixture with 10% oxygen (GHM-10).

ACTH

STH

TSH

insulin

C-peptide


Input: The abscess was debrided and the septum was patched with a single layer of autologous pericardium.


Input: In 18% lymphography was clearly positive and CT negative.


Input: The present study examined the effect of intensity, rate, and polarity on the spectral content of ABRs of 15 normal-hearing subjects.


Input: Similar memory impairments found in medial septal-vertical diagonal band of Broca and nucleus basalis lesioned rats: are memory defects induced by nucleus basalis lesions related to the degree of non-specific subcortical cell loss? The function of nucleus basalis (NB) and medial septal-vertical diagonal band of Broca (MS-VDBB) in a place navigation task requiring reference memory was investigated.


Input: Studies also have alluded to a relationship between the MSMR cyst and certain signs or symptoms of disease.


Input: The BAL-to-plasma specific activity of urea was about twice that of Na +, indicating that urea diffused into the ELF more rapidly than Na + during the 70 s that elapsed between the time the radioactive urea and Na + were injected into the circulation and the time when lavage was complete.


Input: The kappa coefficient of agreement between the Patho Dx Kit and the standard method was 0. 958.


Input: Senior systems--45; Mental health and illness in old age--3.


Input: When normalized for imaging time, all parameters are significantly higher with RASE, with a C/A per unit time that was 338% higher.


Input: Patients with acute myocardial infarction had higher plasma concentrations of neutrophil elastase and the non-peroxide diene conjugated isomer of linoleic acid than normal volunteers or patients with stable ischaemic heart disease.

neutrophil elastase


Input: The cis-acting element, identified as CACGTGACCCG, is located 34 bp upstream from the transcription initiation site, and contains the core sequence of the upstream promoter sequence of Ad2MLP.


Input: The clinical relevance of these findings is strengthened by the observation that similar results were obtained when P. HCl was given by the intravenous route.


Input: TMBr-1 is identical to striated muscle alpha-tropomyosin from amino acids 1 through 258 but contains a novel COOH-terminal region from amino acids 259 through 281.

striated muscle alpha-tropomyosin


Input: The procedure has been applied to three materials: particle board with carpet; gypsum board with wallpaper; and plywood with polyurethane lacquer, for which the steady-state emission factors (mg m-2 h-1) of several compounds are given.


Input: Intron 1 is 6. 5 kb long, and the minimal sizes of introns 2 and 3 are estimated to be 32 kb each.


Input: After 4 h, lesions in the secretory part of the stomach were scored and mucosal prostaglandin E2 synthesis was determined by the ex vivo prostaglandin generation technique.


Input: Comparison of transmembrane and cytoplasmic domains to a third cell-surface proteoglycan, 48K5 from human lung fibroblasts (Marynen, P., Zhang, J., Cassiman, J., Vanden Berghe, H., and David, C.


Input: Approximately 65% of the total cAMP-dependent phosphotransferase activity is recovered in particulate fractions of homogenates prepared from asynchronous populations of C. elegans.

cAMP-dependent phosphotransferase


Input: High levels of C subunits are observed in several subsequent larval and adult stages of development.

C subunits


Input: A second, novel C subunit (CeCAT alpha', 374 residues) has a unique 56-residue carboxyl-terminal region that is generated by the alternative splicing of the C pre-mRNA.

CeCAT alpha'

C pre-mRNA


Input: The alternative exon introduces the novel carboxyl terminus and a new translation stop signal, while simultaneously converting the coding sequence for 40 carboxyl-terminal residues in CeCAT alpha into 3'-untranslated nucleotides.

CeCAT alpha


Input: French, M.


Input: Slowly adapting type I mechanoreceptor discharge as a function of dynamic force versus dynamic displacement of glabrous skin of raccoon and squirrel monkey hand.


Input: Plasma lecithin/cholesterol acyltransferase (LCAT) activity in multiple-organ donors: a predictor of allograft viability in clinical liver transplantation.

lecithin/cholesterol acyltransferase

LCAT


Input: Axillary nodal status, tumour progesterone receptor status, and season of tumour detection significantly influenced survival in both older (greater than 50 yrs) and younger (less than 50 yrs) patients.

progesterone receptor


Input: The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K +] o is presented.


Input: Expression, cellular localization and in vitro transcription studies establish that cloned hUBF encodes a nucleolar factor that binds specifically to the upstream control element and core of the rRNA gene promoter to activate transcription in a binding site-dependent manner.

cloned hUBF


Input: Combining multiple laboratory studies may be of value in predetermining the eventual outcome in near-drowning.


Input: There was a gradual increase in the myocyte diameter according to age in the biopsy and autopsy specimens.


Input: Despite the absence of exercise-induced asthma (EIA) while breathing WH air, asthmatic patients still had significantly higher mean GH increments than normal subjects (9. 2 vs 2. 3 ng/ml, P less than 0. 05).


Input: The afferents' phase of response was unmodified by electrical EVS stimulation.


Input: Solving an age old problem.


Input: The distribution of their fibrinogen levels was Gaussian, but more wide-based than the distribution of our normal controls.

fibrinogen


Input: In a stepwise logistic regression analysis of SPT and RAST data, the occurrence of serum IgE antibodies to P. orbiculare had the highest explanatory value for current eczema.

serum IgE antibodies to P. orbiculare


Input: The examination was focused on assessment of different types of drusen, on evaluation of the development and incidence of risk factors leading to complications and loss of central vision.


Input: They were then subjected to whole-body heat stress (water-perfused suits), and the 3 minutes of LBNP was repeated.


Input: An NF1-related vitellogenin activator element mediates transcription from the estrogen-regulated Xenopus laevis vitellogenin promoter.

NF1-related vitellogenin activator element

Xenopus laevis vitellogenin promoter


Input: At the carboxyl terminus, deletion as far as residue 388 did not affect in vitro TRF. C assembly, although trans-activating activity was abolished.

TRF. C


Input: The effects of mean luminance were also measured and a general expression that would take them into account was derived.


Input: Effect of hyperglycemia on pain threshold in alloxan-diabetic rats.


Input: We have synthesized [7, 7-2H2]-19-OHA with high deuterium content and, together with [7, 7-2H2] A and [9, 11-2H2] estrone (E1), have developed a quantitative assay of serum level 19-OHA, A, and E1 using the gas chromatography/mass spectrometry-mass fragmentography method to monitor individual subjects throughout pregnancy.


Input: Sequence analysis of these genes and their surrounding sequences are presented and compared with other known tRNA genes from plant mitochondria.


Input: Experiments were performed in which brain-stem auditory-evoked responses (BAERs) were elicited by two types of pseudorandom pulse trains: maximum length sequences (MLS) and Legendre sequences (LGS).


Input: The pseudolymphoma syndrome is a reversible reactive condition consisting of fever, lymphadenopathy and generalized rash.


Input: In the local geomagnetic field, the animals preferred the SE-sector.


Input: In the artificial lung, like in the natural lung and peripheral tissues, gas exchanges depend on several parameters: blood inlet conditions, blood flow rate, temperature, composition of the gas mixture used for ventilation, blood tissue perfusion, O2 consumption, etc.


Input: Mean (+/-SE) measurements of clearance (24. 5 +/-2. 06 v 26. 5 +/-2. 05 mL/min/m2), half-life (5. 7 +/-0. 5 v 6. 4 +/-0. 5 hours), and volume of distribution (12. 4 +/-1. 1 v 13. 7 +/-1. 6 L/m2) were not significantly different in patients with jaundice when compared with controls.


Input: Attitudes were found to be multidimensional, with similar dimensions being identified in both samples.


Input: We conclude that DNA ploidy is a major objective prognostic factor and therapeutic determinant for endometrial carcinoma.


Input: A semiautomatic digital system (Videoplan 2) was used.


Input: Environmental factors were more important in the older cohorts (perhaps because of less reliable recall).


Input: Dopamine SERS spectra from these electrodes are similar to those obtained at uncoated electrodes.


Input: These findings indicate that hypergastrinemia induced by surgical removal of acid-producing mucosa in the rat has the same effects on oxyntical mucosal HDC activity, histamine concentration and ECL cell density as hypergastrinemia induced by continuous gastrin infusion or by long-term treatment with effective antisecretagogues.

mucosal HDC


Input: The order of the helicase motif and the nsP3 homology region in the RUB genome is reversed with respect to the alphavirus genome indicating that a genetic rearrangement has occurred during the evolution of these viruses.

helicase motif

nsP3 homology region


Input: The results suggest followings--1) both eosinophils and neutrophils participate in hypersecretion of type Ib in atopic cases, and only eosinophils in non-atopic cases.


Input: There were 5 treatments: control (C); a wooden surround in one rear corner of the cage (S); a fiberglass rollaway hollow in one rear corner of the cage (H); a hollow and a surround (H/S); a nest box attached to the back of the cage, containing a hollow (N).


Input: While no significant differences in the tensile responses or failure characteristics were noted for irradiated and nonirradiated grafts in the drip, in the bath environment the nonirradiated tissues had greater strength and modulus.


Input: The patient was treated with benzathine penicillin, 2, 400, 000 U weekly for three weeks.


Input: A consensus binding site for the transcription factor SP1 was identified in intron As downstream of the proenkephalin germ cell cap site region.

proenkephalin germ cell cap site region


Input: This proposed method is similar in principle to the sets technique but is shown to have much better expected time to alarm properties.


Input: Drug and personnel costs were reduced when batch manufacturing with 40-mL multidose vials was compared with extemporaneous compounding with unit-dose vials.


Input: Changes in prognosis of twin births over 20 years.


Input: Dermal toxicity and carcinogenicity of 4-vinyl-1-cyclohexene diepoxide in Fischer rats and B6C3F1 mice.


Input: Per kg FFM SMR was almost restored to baseline values for the EX group, whereas the non-exercising subjects still showed depressed values (EX 3. 7 per cent and D + DE 15. 8 per cent lower than before treatment; P less than 0. 05).


Input: MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor.

carbonic anhydrase


Input: PCR-derived fragments were used as probes for the isolation of the U3 snRNA genes from a genomic library of Arabidopsis.

U3 snRNA genes


Input: The transcriptional unit spans a chromosomal region of about 55 kilobase pairs (kbp).


Input: 100 of the patients who would have died survive.


Input: The effects of tap (TW) or carbonated (CW) water on arterial pH, partial pressure of carbon dioxide (PCO2) and plasma lactate were determined in heat-stressed broilers.


Input: Transient expression of human and chicken progesterone receptors does not support alternative translational initiation from a single mRNA as the mechanism generating two receptor isoforms.

human and chicken progesterone receptors


Input: The Community Adjustment Scale provided outcome data related to the subjects' degree of productivity, ability to maintain close relationships, and presence/absence of symptomatology an average of 32 years after initial admission.


Input: However, at 18 months of age, significantly higher levels of IgG1 (P less than 0. 05) and of IgG4 (P less than 0. 01) were found in infants with an elevated IgE (greater than or equal to 8. 0 kU/l) than in those with a lower level.

IgE


Input: The protein sequence contains seven potential N-linked glycosylation sites and a threonine/serine-rich region which is a potential site for attachment of O-linked carbohydrate.


Input: Thus adaptation to continuous mild stress has a potent antiarrhythmic effect which occurs due to the increased vagal tone.


Input: The eluent from the column was mixed with the chemiluminescent solution containing lucigenin and Triton X-100 and a 0. 28 M KOH solution by pumps and monitored by a chemiluminescence detector.

lucigenin


Input: On histologic examination the cuboidal epithelium of the mucous membrane was found to be changed into columnar epithelium, with uneven distribution of enlarged nuclei in the vacuolized cytoplasm.


Input: These results suggest an increased risk of developing cancer among polyp patients and the possibility of prophylactic effect of polypectomy against subsequent cancer.


Input: The same trend was noted between YG 4. 5 heifers and YG 5. 5 steers, indicating a sex-related deposition of seam fat in fed cattle.


Input: The nucleotide sequence consists of 48 bp of 5'-end non-coding region, 1695 bp of coding region and 212 bp of 3'-end non-coding region including a 20 bp poly (A) tail.


Input: Toxicities included: nausea/vomiting (69%), headache (25%), chills (69%), pain at tumor sites (63%), hypotension (31%), and hypertension (38%).


Input: The results also showed that although oyster shell supplementation generally increased alkaline phosphatase activity, bone mineralization was relatively uninfluenced as judged by the low coefficients of variation (CV) of 3. 14-3. 51% and 3. 39-4. 82% for calcium and phosphorus content in the femur and tibia respectively.

alkaline phosphatase


Input: In 6 of 24 infants studied (27th-40th weeks of gestation), acquired and congenital structural anomalies of the airways were detected with an ultrathin flexible fiberscope (Olympus PF18 S, 1. 8 mm).


Input: Fatal encephalitis in a patient with chronic graft-versus-host disease.


Input: Compared to its counterpart in the GPB gene, exon 3 of the GPE gene contains several point mutations, an insertion of 24 bp, and a stop codon which shortens the reading frame.

GPB gene

GPE gene


Input: Molecular cloning of a cDNA encoding rat NADH-cytochrome b5 reductase and the corresponding gene.

rat NADH-cytochrome b5 reductase


Input: The results corroborate the idea that the structure of relaxation curves contains information on the distance scale and on the architecture of the pore space, even if it is difficult to extract it without ambiguities.


Input: Serotonin 5-HT2 receptor binding on blood platelets as a state dependent marker in major affective disorder.

Serotonin 5-HT2 receptor


Input: Although% BF was correlated with all the BMIs (r = 0. 60-0. 82), applying objective definitions of obesity based on BMIs or% BF by densitometry often produced conflicting results.


Input: The RF values correlated well with the angiographic semiquantitative scale of severity of aortal insufficiency (r = 0. 805; p less than 0. 001), although they enabled the authors only to make a partial differentiation of haemodynamically severe regurgitations and mild or insignificant ones.


Input: Promoter elements include an atypical TATA box (GTTA), one CCAAT box much further from the initiation site, three reverse compliments of CCAAT (ATTGG), and two pyrimidine-rich nucleotide stretches.


Input: The cloned genes were identified in genetic libraries by hybridization screening using four deoxyoligonucleotide probes which corresponded to the partial amino acid sequence of the purified enzyme.


Input: The pattern for catalytic zinc sites included two ligands close in sequence, a sequence-distant ligand, and a main-chain hydrogen bond joining two ligands.


Input: Results of the long-term observation and treatment of patients with arterial hypertension


Input: Eucaryotic transcription factors that stimulate RNA polymerase II by increasing the efficiency of elongation of specifically or randomly initiated RNA chains have been isolated and characterized.

RNA polymerase II


Input: Sprague-Dawley newborn rats (n = 85) breathed 100% oxygen (O2) or room air (RA) during the first 8 days of life, and then RA.


Input: The Lm increased and the alveoli/mm2 and elastic recoil pressure decreased.


Input: In Experiment II, as performing moderate supine cycling (55% VO2 max) for 50 minutes under several LBNP conditions in 5 sedentary women, there were correspondingly similar changing manners of the cardiovascular adjustments to each of the phases given in Experiment I.


Input: Commercially available formulations of 2. 5% and 5% lambdacyhalothrin can be diluted either with water for ULV cold aerosol space-spraying or with diesel/kerosene for thermal fogging at recommended application rates of 0. 5-1 g ai/ha for mosquito control and 2 g ai/ha for housefly control.


Input: Thus, this reading frame was concluded to encode the precursor of mitochondrial fumarase.

mitochondrial fumarase


Input: Sequence analysis indicates that in addition to an ATA and GC box, this region contains domains that have been implicated in the regulation of other muscle-specific genes: a CArG box at-91 bp; myocyte-specific enhancer-binding nuclear factor 1 binding site homologies at-58,-535, and-583 bp; and a muscle-CAAT consensus sequence at-394 bp relative to the cap site.

myocyte-specific enhancer-binding nuclear factor 1 binding site


Input: The trk-2h oncogene, isolated from the human breast carcinoma cell line MDA-MB 231 by genomic DNA-transfection into NIH3T3 cells, consists of the trk proto-oncogene receptor kinase domain fused to a N-terminal 41 amino acid activating sequence (Kozma, S. C., Redmond, S. M. S., Xiao-Chang, F., Saurer, S. M., Groner, B. and Hynes, N. E.

trk-2h oncogene

trk proto-oncogene receptor kinase domain


Input: Antibodies raised against a bacterially produced beta gal-trk receptor kinase fusion protein recognized a 44 kd phosphoprotein phosphorylated on serine, threonine and tyrosine in extracts of trk-2h transformed NIH3T3 cells.

beta gal

trk


Input: Since very recent scanning-deletion analysis indicates that there is a critical region for activity near Cys-118 and that Cys-118 is necessary for maximal activity, we conclude that the Cys-118 residue is necessary for proper glycosylation and maximal biologic activity of GM-CSF.

GM-CSF


Input: Molecular and functional characterization of the promoter of ETS2, the human c-ets-2 gene.


Input: Information about immunologic drug interactions is needed by pharmacists to make rational drug-use decisions.


Input: Branch occlusion of Heubner' s artery, or perforators from the proximal anterior or middle cerebral arteries were the posited mechanism of infarction.


Input: All ABFI-binding sites, regardless of origin, provided weak UAS function in vivo when examined in test plasmids.

ABFI-binding sites


Input: An examination of the properties of sequences surrounding ARS1 left open the possibility that ABFI enhances the initiation of DNA replication at ARS1 by transcriptional activation.

ABFI


Input: Likewise, whether or not the hypotensive action of converting enzyme inhibitors is age-related is as yet unknown.


Input: Polyclonal antiserum generated to the fusion protein was capable of detecting 42-and 46-kilodalton polypeptides from virus particles; both polypeptides were also shown to contain HBsAg determinants.

HBsAg determinants


Input: Role of superoxide dismutase in cellular oxidative processes and method of its determination in biological materials

superoxide dismutase


Input: At maximum photosensitivity the inhibitory amino acids gamma-aminobutyric acid and taurine were lower, and those of asparagine (metabolite of the excitatory amino acid aspartate) were higher, than when the animals were not photosensitive.


Input: The priming activity of DNA incised by either of the Drosophila enzymes can be enhanced, however, by an additional incubation with E. coli endonuclease IV, which is known to cleave depurinated DNA on the 5'-side of an apurinic site.

E. coli endonuclease IV


Input: A.


Input: Therefore, in conjunction with a positive pregnancy test and the patient' s clinical history, a severely depressed or absent serum PAPP-A level may aid in the diagnosis of extrauterine pregnancy.

PAPP-A


Input: The levels of both MAP1-specific and MAP2-specific mRNAs decline in the postnatal developing brain; the level of MAP1-specific mRNA also increases slightly in rat PC12 cells upon exposure to nerve growth factor.

MAP1-specific and MAP2-specific mRNAs

MAP1-specific mRNA

nerve growth factor


Input: The cDNAs cross-hybridize with genomic sequences in rat, human, and chicken DNA, but not with DNA from frog, Drosophila, or sea urchin.


Input: Colorimetric method of determining glycerin in the blood


Input: Deletion analysis was carried out within a part of the 5'-flanking region showing homology to the upstream region of the yeast CYC1 gene.

yeast CYC1 gene


Input: The N1 and P2 were comparable in amplitude and both had prolonged refractory periods.


Input: Tolerance to fenfluramine anorexia: fact or fiction? Recent findings in this laboratory with regard to tolerance to fenfluramine anorexia are reviewed with respect to generality of the behavioural phenomenon.


Input: In 30 dogs the left limb (tail) of the pancreas was removed but left in the abdominal cavity after cessation of blood flow to produce warm ischemia for 30, 60, and 120 min (10 dogs at each time point), and then was flushed with cold Ringers' lactate and transplanted to the iliac vessels.


Input: Furthermore, beta 2-adrenoceptor sensitivity appears to be unaltered in BHT.

beta 2-adrenoceptor


Input: These results suggest that the negative inotropic action of nicorandil is caused by inhibition of Ca influx and intracellular mobilization of Ca.


Input: Comparison of elastase-1 with amylase, lipase, and trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.

amylase

lipase

trypsin


Input: A probe evoked potentials procedure was used to assess the relative engagement of both cerebral hemispheres during a language task in the following four groups of dextral adults: left hemisphere (LH)-damaged aphasics recovering from stroke, dysarthrics, right hemisphere (RH)-damaged nonaphasic patients, and normal control subjects.


Input: Mucolipidosis type IV: clinical spectrum and natural history.


Input: Two of the three groups were administered dauricine, as a new calcium channel blocker, and verapamil, as a generally recognized calcium channel blocker, respectively, from 15 minutes pre-bypass to the end of the bypass procedure (a period of 95 minutes).


Input: No reflow occurred in approximately 30 percent of the muscle microvasculature upon reperfusion.


Input: Lysozyme activity was evidently increased as well in undiluted as in diluted sera in all our tested patients.

Lysozyme


Input: The first involved measurements of the steady state levels of mRNAs for subunit 5 of cytochrome oxidase and the beta subunit of F1 ATPase in wild type and in a hem2 mutant.

cytochrome oxidase

F1 ATPase

hem2 mutant


Input: A 5. 8S-like structure is present within the 5'-terminal region of all three fungal mitochondrial LSU rRNAs; in contrast, no 4. 5S-like structure is evident at the 3' end of these molecules.

5. 8S-like structure

fungal mitochondrial LSU rRNAs

4. 5S-like structure


Input: The recovery of labelled methoxydextrane is 98 +/-7%.


Input: ASL-8123 demonstrated weak competitive beta-adrenoreceptor blocking activity in isolated guinea pig right atria with a pA2 of 3. 73 +/-0. 07; no agonist-like activity was observed in this tissue at concentrations of ASL-8123 from 3 X 10 (-5) to 1 X 10 (-2) M.

beta-adrenoreceptor


Input: We discuss the results in relation to previous systems for parcellating the posterior ectosylvian gyrus of the cat and consider the possibility that divisions of the feline posterior ectosylvian gyrus correspond directly to areas making up the superior temporal gyrus in primates.


Input: The 4-AP (4-20 mM) effect resulted in a decrease of the sensory activity, which was fully restored by TEA or Ba2 +.


Input: Hybridization of a probe from this region to electrophoretic blots of RNAs from different human tissues showed a predominant 2. 8-kilobase (kb) message accompanied by weaker bands 4. 1 and 2. 1 kb in size.


Input: Prognosis of asymptomatic multiple myeloma.


Input: A new method for the quantitative analysis of sleep spindles during continuous overnight EEG recordings.


Input: Svensson et al.


Input: Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection.


Input: In this report we describe for the first time the complete primary structure of type X collagen, based on cloning and sequencing of cDNA and genomic DNA.

type X collagen


Input: Viable flap areas were established following vascular pedicle ligation (both vessels or only artery or vein), on the third day after flap replantation in both island and free flaps.


Input: The size discrepancy is not due to glycosylation or phosphorylation of Ag35 but may result from a proline-rich sequence which occurs in this polypeptide.


Input: A 9. 5-kb KpnI-SalI fragment, where all the DNA changes associated with su (Hw) mutations were mapped, was able to rescue the su (Hw) mutant phenotype after P-element-mediated germ-line transformation.

KpnI

SalI

su (Hw) mutations

su (Hw) mutant


Input: The corticosterone synthesis inhibitor metyrapone (75 mg/kg i. p.) was given to attenuate the rise of corticosterone to a level typical of stressed males.


Input: The effects of L655, 240, a selective thromboxane and prostaglandin endoperoxide antagonist, on ischemia-and reperfusion-induced cardiac arrhythmias.


Input: In 10 pentobarbitalized dogs, plasma viscosity (Ep) was raised fourfold while apparent blood viscosity (Ea) increased about twofold by two steps of exchange transfusion of 200 ml of plasma with plasma containing high molecular weight dextran (mol wt 500, 000, 20% wt/vol).


Input: The small IGF-binding protein is abundant in human amniotic fluid.

small IGF-binding protein


Input: Serum prostatic acid phosphatase levels showed a significantly weaker correlation with cancer volume (r equals 0. 51) and every other pathological parameter.

prostatic acid phosphatase


Input: The investigation was thereafter continued in an open fashion by administering a single 10 mg dose of the MAO-B inhibitor deprenyl to the same subjects.

MAO-B


Input: Their studies have revealed a considerable increase of CSF AP activity in purulent meningitides whereas in serous meningitides it grows negligibly.

CSF AP


Input: A cDNA encoding a new human lymphocyte cell surface molecule has been isolated and shown to identify a fourth member of a recently discovered family of adhesion proteins.


Input: Dopamine caused a prominent potassium efflux measured as 86Rb + efflux from control glands, but was without effect in denervated glands.


Input: This approach was examined utilizing the fetal protein, HGB F.

HGB F


Input: The investigation was apt at studying the relationship between urinary metabolites of serotonin and catecholamine (5-HIAA and VMA), T-cells (OKT3 +), T-helper (OKT4 +), T-suppressor (OKT8 +) and B-cells (EAC-rosette forming cells) in normal (10 subjects, 1 female, 9 male, age 21 +/-5 years) and stress administered subjects (20 subjects, 3 female, 17 male, age 20 +/-4 years).

OKT3 +

OKT4 +

OKT8 +


Input: Their hydropathic plots are very similar and both possess three hydrophobic segments that are likely alpha-helical transmembrane segments.


Input: Angiotensin converting enzyme inhibitors enhance the antihypertensive efficacy of diuretics and blunt or prevent adverse metabolic effects.

Angiotensin converting enzyme


Input: In addition to the significant reduction in blood pressure, the angiotensin converting enzyme (ACE) inhibitor ramipril caused a significant regression of pathologic left ventricular hypertrophy demonstrated by magnetic resonance imaging and echocardiography.

angiotensin converting enzyme

ACE


Input: The ratio of radioactivity in tumour compared with normal tissue (T: N ratio) was determined after simultaneously injecting microspheres into the portal and arterial circulation of each animal.


Input: The mRNA was converted to cDNA and amplified by the polymerase chain reaction technique.


Input: Tissue necrosis was evaluated using triphenyltetrazolium staining and was related to two major baseline predictors of infarct size: anatomic risk zone size and coronary collateral flow.


Input: To study the retinal surface in the human eye in normal and diseased states we used laser scanning tomography.


Input: Previously, we reported the sequence of the gene encoding human K14 (D.

gene encoding human K14


Input: Cotransfection of either construct with plasmids encoding PKI (1-31) inhibits cAMP-stimulated but not basal-or phorbol ester-stimulated expression.

PKI (1-31)


Input: Sequence analysis of the 5' flanking region revealed several GC boxes but no identifiable TATA box.


Input: The underlying cirrhosis was alcoholic in 11 (53. 3%), cryptogenic in 5 (23. 8%), and hepatitis B chronic infection related in 5 (23. 8%).


Input: Once P-450scc mRNA is induced as a consequence of the LH/hCG surge it is constitutively maintained by luteinized cells in vivo (0-4 days) and in vitro (0-9 days) in the absence of gonadotropins, is susceptible to modulation by prolactin and is no longer regulated by cAMP.

P-450scc mRNA

LH

hCG

gonadotropins

prolactin


Input: Similarly, a human but not a bovine alpha transgene was expressed in placenta in transgenic mice.

bovine alpha transgene


Input: A rapid staining technique for Leishmania parasites in splenic aspirate smears.


Input: NIK-244 suppressed coronary ligation-and digitalis-induced arrhythmias, and the minimum effective plasma concentrations for arrhythmias induced by 24-h and 48-h coronary ligation and digitalis were 0. 41 +/-0. 10 (by 1 mg/kg i. v.), 0. 70 +/-0. 13 (by 1 mg/kg i. v.), and 0. 21 +/-0. 08 (by 0. 5 mg/kg i. v.) microgram/ml, respectively (mean +/-SD of the mean, n = 6).


Input: In TNF-resistant T24 bladder carcinoma cells, TNF failed to alter EGF-R tyrosine protein kinase activity although both EGF and phorbol ester were shown to modulate the enzymatic activity of the receptor in these cells.

TNF

TNF

EGF-R tyrosine protein kinase

EGF


Input: Thus, phosphodiesterase inhibitors that produce an opiate quasi-withdrawal syndrome potentiate interoceptive stimuli and weight loss associated with the withdrawal syndrome precipitated by naltrexone in morphine-dependent rats.


Input: The diagnostic value of blood serum and urinary amylase, lipase, and trypsin in exacerbations of chronic relapsing pancreatitis is discussed.

urinary amylase

lipase

trypsin


Input: On the basis of the mechanism of action, two groups of inodilators are distinguished, the phosphodiesterase inhibitors and the dopaminergic agents.


Input: Structural organization and expression of the mouse estrogen receptor.

mouse estrogen receptor


Input: Intravenous gamma globulins


Input: Following chondroitinase AC and ABC digestion, staining reactions suggested that the highest levels of dermatan sulfate were in the diabetes resistant group (p less than 0. 001 compared to diabetic, p less than 0. 001 compared to diabetes prone) and the highest levels of chondroitin sulfates were in the diabetes prone group (p less than 0. 001).

chondroitinase AC and ABC


Input: Myocardial perfusion was evaluated using the enhanced gray level after contrast injection, and the level was compared with the morphology and degree of collateral development.


Input: Once NGF administration is proven effective it will be possible to develop alternative ways of NGF administration.

NGF

NGF


Input: During the program' s use at the RSNA meeting, the program selected the correct diagnosis in the top five 22% of the time.


Input: Immunoglobulin light chain (IgL) diversity is generated in the chicken by recombination between the single functional variable (VL) and joining (JL) gene segments and subsequent somatic diversification of the rearranged VL region.

Immunoglobulin light chain

IgL

VL

JL

VL


Input: The results were as follows: 1) Total integrated EMG activity of FB group was approximately equal in any occluded position, whereas that of CG and GF group varied from position to position.


Input: Muscle action potential and masticatory rhythm of anterior temporal and masseter muscles in children and adults


Input: The thrombolytic effects of native tissue-type plasminogen activator (AK-124) on experimental canine coronary thrombosis.

tissue-type plasminogen activator


Input: O2 and CO2 in the tracheostomy tube were continuously monitored by mass spectrometry using a special sample-hold phase-locked sampling technique.


Input: Enzyme-linked immunosorbent assay for screening aflatoxin B1 in cottonseed products and mixed feed: collaborative study.


Input: However, experiments with S1 mapping of in vivo transcripts, gene disruptions in the alpha region, and a single-copy transcriptional fusion vector all suggested that these possible promoters were largely inactive during logarithmic growth, that the major promoter for the alpha operon lay upstream from the region cloned, and that the genes in the IF1 to L17 interval were cotranscribed.


Input: Two specific DNA-protein complexes were identified in gel retardation assays using HeLa cell nuclear extracts and an oligonucleotide probe spanning the footprinted region.


Input: After transfection, specific TSH beta promoter activity was evident in both TRH-responsive pituitary-derived GH3 and primary pituitary cell cultures.

TSH beta promoter

TRH


Input: In transformed E. coli, constitutive CAT expression is maintained when as little as 0. 3 kilobase of DNA from the 3' end of the 1. 6-kilobase segment is inserted in the correct orientation in front of the CAT gene.

constitutive CAT

CAT gene


Input: Lowering of the renal blood flow alters the glomerular and tubular excretion processes.


Input: Tonometry of blood samples from patients may also be used in the determination of acid-base quantities and hemoglobin-oxygen affinity e. g. p50.

hemoglobin


Input: 100 and 14 p.


Input: Here, we alter the dimerization specificity of Fos by precisely replacing its leucine zipper with that from GCN4.

Fos


Input: Fourth, sometime between 4 and 24 hours of recovery is necessary to reverse the effect of chronic hypoxia on cerebral blood flow.


Input: Kindling of the primary visual cortex (VC) was compared with that of the amygdala in cats.


Input: Abundant infiltration of lymphocytes and plasma cells was also wide-spread beneath the carcinoma in situ, together with the lymphoid follicles.


Input: These case reports provide further evidence that LiCO3 can be a useful medication in the treatment of aggressive behavior and affective instability after brain injury, but that it has significant potential for neurotoxicity in this population, particularly when used in conjunction with neuroleptic agents.


Input: Among 100 cases of post-transfusion hepatitis, 10 are due to the hepatitis B virus (despite systematic search for HBs Ag), 89 are due to one of the non-A non-B viruses (not detectable by specific serological tests) and 1 to several viruses, specially CMV.

HBs Ag


Input: Recessive lethal mutations were isolated based upon failure to complement the recessive lethality of Df (3L) RR2, a deletion of the DRE region that removes 16-18 polytene chromosome bands.


Input: Current status and future perspectives


Input: K.


Input: A 215-base-pair (bp) region of the mouse MOPC 41 kappa light-chain immunoglobulin gene enhancer has been analyzed for specific binding of lymphoid and nonlymphoid nuclear factors.

mouse MOPC 41 kappa light-chain immunoglobulin gene enhancer


Input: Follow-up study showed 85% of these patients with effectiveness.


Input: The other patients continued the trial with single daily doses of monotherapy.


Input: Neonatal Chagas disease: laboratory diagnosis during the first year of life


Input: Using mutated IL2R alpha promoter constructs in transient transfection and DNA binding assays, we now demonstrate that sequences located immediately upstream and downstream of the kappa B enhancer also contribute to the regulation of IL2R alpha gene expression.

mutated IL2R alpha promoter constructs

kappa B enhancer

IL2R alpha gene


Input: Palindromic rheumatism


Input: Forty patients, divided according to their initial total gastrointestinal transit times and presenting symptoms, were treated with cimetropium bromide 50 mg t. d. s. or placebo for 1 month according to a double-blind, parallel group design.


Input: An immunologically related protein was detected in ribosome and membrane fractions of mitochondria from Saccharomyces cerevisiae.


Input: Mapping of RNA-temperature-sensitive mutants of Sindbis virus: complementation group F mutants have lesions in nsP4.

temperature-sensitive mutants of Sindbis virus: complementation group F mutants


Input: The effect of the thromboxane A2 (TXA2)/prostaglandin endoperoxide receptor antagonist, SQ 29, 548 on pacing-induced ischemia was determined in anesthetized open-chest dogs.

thromboxane A2 (TXA2)/prostaglandin endoperoxide receptor


Input: The recovery index (T25-T75) after the infusion stopped was similar in patients who received mivacurium and those who received suxamethonium.


Input: The sign of Leser-Trelat: does it exist? The sign of Leser-Trelat is usually regarded as a reliable cutaneous marker of internal malignancy.


Input: Three missense mutants in subunit a of the Escherichia coli F1F0-ATPase were isolated and characterized after hydroxylamine mutagenesis of a plasmid carrying the uncB (subunit a) gene.

Escherichia coli F1F0-ATPase

uncB (subunit a) gene


Input: Moreover, exons 2a and 2b share the same 5' sequence but differ from each other by the use of two distinct donor splice sites 171 bp apart in the gene.


Input: S1 nuclease analysis of RNA prepared after transfection of these HIV constructs into HeLa cells infected with wild-type adenovirus indicated that the enhancer, SP1, TATA, and a portion of the transactivation-responsive element were each required for complete E1A/E1B-mediated activation of the HIV LTR.

S1 nuclease

HIV LTR


Input: In supine position, plasma ANP levels ranged from 12 pg/ml to 51. 5 pg/ml, with an average level of 35. 3 +/-11. 5 pg/ml.

ANP


Input: The overall prevalence of HBV markers was higher among staff members than in the blood donors of our area.


Input: Quantitative predictions are confirmed for the positive responses, but not for the negatives, suggesting that the SSTS model is incorrect.


Input: Plasma concentrations of ANF (pANF), aldosterone (PAC) and renin (PRC) were measured daily, as were hemodynamic parameters.

ANF

pANF

renin

PRC


Input: The adenovirus E1A gene encodes a protein that transcriptionally activates viral early genes.

adenovirus E1A gene

viral early genes


Input: Administration of dexamethasone was associated with progressive rises in plasma 17 alpha OH progesterone, 11 beta-desoxycortisol, DHEA sulphate, androstenedione and testosterone, together with increased urinary excretion of androsterone, 11 beta OH androsterone, etiocholanolone, DHEA, and 16 alpha OH DHEA.


Input: RNA transcripts that hybridize to the introduced foreign gene have been identified.


Input: In HeLa cells, it activated transcription from the herpes simplex virus type 1 thymidine kinase promoter linked to the chloramphenicol acetyltransferase gene when located in inverted orientation upstream of the thymidine kinase promoter or downstream of the chloramphenicol acetyltransferase gene coding sequence.

herpes simplex virus type 1 thymidine kinase promoter

chloramphenicol acetyltransferase gene

thymidine kinase promoter

chloramphenicol acetyltransferase gene coding sequence


Input: At the basal unstimulated condition, Ren1d 5' flanking sequence in the sense orientation inhibited basal CAT expression from the TK promoter of pUTKAT1, whereas the same sequence in the antisense orientation did not.

Ren1d 5' flanking sequence

CAT

TK promoter


Input: None were restricted from clinical duties, were given varicella-zoster immune globulin, or developed disease.

varicella-zoster immune globulin


Input: In the formalin test, however, naloxone attenuated morphine analgesia at the lower doses (0. 1 and 0. 3 mg/kg) and potentiated morphine analgesia at the highest dose (10 mg/kg).


Input: We have isolated cDNA clones from rat brain and human liver encoding a putative isoform of the Na, K-ATPase beta subunit.

Na, K-ATPase beta subunit


Input: We have determined that several E1 mutants mapping in both the M and R regions and a single mutant of the upstream regulatory region have a higher transforming activity on mouse C127 cells than the wild-type genome does.

E1 mutants


Input: UbiA is also unique among known polyubiquitin genes in containing four cis-spliced introns within its coding sequence.

UbiA

polyubiquitin genes


Input: That of the T2 gene contains numerous potential sites for binding the mammalian transcription factor SP1, but no TATA or CCAAT sequences are evident near to its 5' end, although these latter features are associated with the human T1 gene.

T2 gene

mammalian transcription factor SP1

human T1 gene


Input: Radiation therapy was effective in controlling symptomatic metastasis in all three patients.


Input: These results indicate that patients who undergo postoperative irradiation for low grade spinal astrocytomas and localized spinal ependymomas achieve excellent survival.


Input: The methylation of nuclear and chloroplast DNAs has been examined in relation to the known differential expression of C4 photosynthesis genes in the bundle sheath and mesophyll cells of etiolated, greening, and fully green maize leaves.

C4 photosynthesis genes


Input: S1 nuclease analysis of RNA from chemically induced B95-8 cells and from Vero cells cotransfected with NotI repeat promoter-CAT and Z showed that Z transactivation increased the level of correctly initiated, stable RNA transcripts.

S1 nuclease

NotI repeat promoter

CAT

Z

Z


Input: Analysis of the DNA from 15 cases of sporadic and familial Wilms' tumor did not reveal any changes, indicating that the translocation breakpoint does not reside in this gene.


Input: We also provide evidence that neither the lambda O and P initiators nor the E. coli DnaJ and DnaK heat shock proteins play a direct role in the propagation of lambda replication forks in vitro.

lambda O

P initiators

E. coli DnaJ

DnaK


Input: Synthetic oligonucleotides representing the 19 bp repeat unit strongly reduced the activity of the IE1/2 enhancer/promoter in cotransfection assays after transient expression.

IE1/2 enhancer/promoter


Input: Effects of nitrogen (PN2: 5 and 14 MPa) and helium (PHe: 13 and 14 MPa) were also tested.


Input: The mustard chloroplast gene rps16 is split by an 887 bp group II (or III) intron.

mustard chloroplast gene rps16


Input: Antibodies raised to the expressed NS3 by immunization of mice detected both NS3 and NS3A in BTV-10-infected BHK cells but not in purified BTV-10 virus particles.


Input: Similarly, supraventricular tachycaydia following resuscitative efforts appeared to be associated with a negative outcome.


Input: The negative calcium balance with hyperparathyroidemia occurred after continuous oral administration of Cd and developed via increased urinary excretion of calcium.


Input: Clone 4c (2681 bp) had a coding region identical to that of clone 22c but it included a putative intron of 959 bp.


Input: The application of ISH and IHC did not change significantly the routine histologic classification of pneumonias into CMV-IP and IIP.


Input: Validity of immunohistology and in situ hybridization in the differential diagnosis of cytomegalovirus pneumonia and idiopathic interstitial pneumonia after allogenic bone marrow transplantation


Input: The unique nature and arrangement of the ANT1 transcriptional control elements may account for this differential expression.

ANT1 transcriptional control elements


Input: The Bacillus subtilis phage phi 105 repressor, a lambda repressor-like transcriptional regulatory protein, was overproduced in Escherichia coli and purified to near homogeneity in order to examine its in vitro DNA-binding properties.

Bacillus subtilis phage phi 105 repressor

lambda repressor


Input: In consequence, the gpI derived from cells infected with mO74 showed antigenic characteristics similar to those of gpI from VZV-infected cells as determined from the immunoprecipitation pattern, although the molecular weight of each polypeptide was different, and antibody produced in rabbits infected with recombinant virus had a high neutralizing activity, when the reaction was performed with complement.

gpI

gpI


Input: However, bilateral diffuse pulmonary infiltrations developed 21 days later.


Input: Grossly, the incidence of a type IIc carcinoma was 46. 5% and that of a IIc + III type was 20. 5%, respectively.


Input: VP5, which encodes the major capsid protein, each fused to the chloramphenicol acetyltransferase gene.

major capsid protein

chloramphenicol acetyltransferase gene


Input: Of 202 initially seronegative caretakers (observed for an average of 305 days per woman), 19 seroconverted, for an annual seroconversion rate of 11 percent.


Input: First, a pet54:: LEU2 cytoductant bearing the' short' mitochondrial genome that lacks both COX1 introns aI5 alpha and aI5 beta is defective only in COX3 gene expression and not in COX1 mRNA splicing or mRNA translation.

COX1 introns aI5 alpha

aI5 beta

COX3 gene

COX1 mRNA


Input: Insert2 contains repetitive non-Ig-related sequences and a small Ig-related sequence.

Ig

small Ig-related sequence


Input: Since considerable variations in length and primary sequence in the CDR3 (complementarity determining region) peptides of all the H-chains are evident, conservation of the D-region structure does not appear to be necessary for effective hapten binding.

complementarity determining region

H-chains

D-region


Input: Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl.

Tyrosine kinase

c-myc

c-myc

v-abl


Input: The DNA helix at the tandemly repeated, 13mer sequence is thermodynamically unstable, as evidenced by hypersensitivity to single-strand-specific nuclease in a negatively supercoiled plasmid, and demonstrated by stable DNA unwinding seen after two-dimensional gel electrophoresis of topoisomers.

single-strand-specific nuclease


Input: There has been similar improvement in treating ampullary and periampullary cancer, gallbladder cancer, or extrahepatic bile duct cancer.


Input: Beta-endorphin, ACTH and cortisol secretion were measured in twelve healthy adult males after nasal spray administration 200 IU salmon calcitonin.

Beta-endorphin

ACTH

salmon calcitonin


Input: The data indicate that calcitonin induced a beta-endorphin increase independent of enhanced corticotrophin-cortisol release.

calcitonin

beta-endorphin

corticotrophin


Input: Other hemostatic values evaluated were activated partial thromboplastin times, prothrombin times, thrombin times, fibrinogen, platelet counts, and fibrin/fibrinogen degradation products.

thromboplastin

prothrombin

thrombin

fibrinogen

fibrin

fibrinogen


Input: Rare neurogenic tumor with metastasis to mouth, jaw and face regions


Input: We have designated the protein " cellular NBP " (CNBP).

" cellular NBP "

CNBP


Input: Responsiveness to beta-2 agonist therapy was retained with both agents (p less than 0. 05).


Input: Drug use in trauma victims.


Input: A critical heart rate and/or appropriate sympathetic state was found to provoke all instances of reentrant or automatic atrial tachycardia and atypical junctional tachycardia.


Input: In contrast, the neu proto-oncogene did not show kinase activity or transforming properties when expressed at similar levels in NIH 3T3 cells. (ABSTRACT TRUNCATED AT 250 WORDS)

neu proto-oncogene


Input: The 65-bp sequence contains the octameric cAMP-responsive enhancer (CRE) TGACGTCA (nucleotides-48 to-41).


Input: Somatostatin gene expression in pancreatic islet cells is directed by cell-specific DNA control elements and DNA-binding proteins.

Somatostatin gene


Input: In contrast, the full mu-opioid agonists fentanyl, morphine, I-methadone and levorphanol produced 50% fentanyl-appropriate responding at doses only 1. 3 to 10. 9 times smaller than those required to decrease response rates by 50%.


Input: After overtraining on the original discrimination, the controls showed the normal difficulty in learning the first reversal.


Input: Isolation and characterization of a cDNA encoding a putative cytokine which is induced by stimulation via the CD2 structure on human T lymphocytes.

CD2 structure


Input: After termination of medication the animals were kindled electrically in the nucleus amygdala.


Input: Haploid cells of mating type A of the basidiomycetous yeast Rhodosporidium toruloides secrete a mating pheromone, rhodotorucine A, which is an undecapeptide containing S-farnesyl cysteine at its carboxy terminus.

rhodotorucine A


Input: Tumour necrosis factor and adult respiratory distress syndrome.

Tumour necrosis factor


Input: Monitoring of rheumatoid arthritis.


Input: The decrease in left ventricular (LV) stroke volume during positive end-expiratory pressure (PEEP) has been attributed to reduced LV filling and a decreased contractile state.


Input: An experiment on the return-of-fear (ROF) was carried out on 40 snake-or spider-phobic subjects in order to determine whether an arousing event that occurs shortly before retest influences the magnitude of the ROF.


Input: Evolutionary conservation of homeodomain-binding sites and other sequences upstream and within the major transcription unit of the Drosophila segmentation gene engrailed.

homeodomain

Drosophila segmentation gene engrailed


Input: To assess the functional importance of these NBS in the overall drug resistance phenotype conferred by mdr1, we introduced amino acid substitutions in the core consensus sequence for nucleotide binding, GXGKST.


Input: When the first twitch of TOF spontaneously recovered to 10% of control value, neostigmine was injected (40 micrograms/kg in adults, 30 micrograms/kg in infants and children).


Input: No significant differences were found in relation to Type A behaviour and beta-adrenoceptor blockade.

beta-adrenoceptor


Input: Selection of the 22 items of the Clinical Institute Withdrawal Assessment-Benzodiazepines (CIWA-B) was based on statistically significant differences between baseline and critical withdrawal periods in high-dose subjects and between symptoms associated with placebo and diazepam in low-dose subjects, using contingency tables and logistic regression analysis.


Input: Northern blot analysis revealed multiple oIGF-I transcripts in a broad band at 800-1, 100 nucleotides and other transcripts of higher molecular weight in liver.

oIGF-I transcripts


Input: Materials science studies on the soldering of different orthodontic wires


Input: The latency time for the lactate concentration to reach the top values was reduced by aerobic training (T2).


Input: In patients resistant to VAD, high-dose therapies with intravenous melphalan, a CBV combination (cyclophosphamide-BCNU-VP-16) or an EDAP regimen (VP-16-platinum) produced responses in about 40% of patients.


Input: The avian cellular homolog of the oncogene jun.

oncogene jun


Input: High ATP/GTP ratios promoted initiation of RNA primer synthesis at 3'-dCTTT sites, whereas low ATP/GTP ratios promoted initiation at 3'-dCCC sites.


Input: After hepatitis B vaccine immunization, serum antibody response was of primary type in 33 cases with anti-HBs less than 2. 1 S/N (S/N Ratio Unit) at T0, the anti-HBs positive rate was 39. 4%, 84. 8%, 96. 7% and 96. 7% in T1, T2, T0 and T12 respectively.

anti-HBs

anti-HBs


Input: The experimental design incorporated a multiple regression model, sequential treatments and a proportional end point (95%) for protection time.


Input: Interspecific complementation tests showed that the P7 proteins are unable to complement P1 parA or parB mutants, and the P1 proteins fail to complement the P7 mutations.

P7 proteins

P1 parA

parB mutants

P1 proteins

P7 mutations


Input: GN101, YC819-9, and SB3.


Input: Analysis of the inferred 1, 859-residue ama-1 product showed considerable identity with the largest subunit of RNAP II from other organisms, including the presence of a zinc finger motif near the amino terminus, and a carboxyl-terminal domain of 42 tandemly reiterated heptamers with the consensus Tyr Ser Pro Thr Ser Pro Ser.

1, 859-residue ama-1 product

RNAP II


Input: None of the measured parameters (heart contents of neutral lipids, total phospholipids, phosphatidylcholine, phosphatidylethanolamine, diphosphatidylglycerol, sphingomyelin and fatty acid composition of each phospholipid class) appeared to be related with the grading of the lesions.


Input: Of 165 women with non-malignant diagnoses 26 (16%) had CA 125 levels in excess of 35 U/ml and 8 (5%) greater than 65 U/ml.

CA 125


Input: We conclude that at steady state the timing of a light meal is unlikely to alter in any clinically important manner the pharmacokinetics of nifedipine released from' biphasic' tablets.


Input: The GALT-primed calves had increased serum IgG, lavage IgG and IgA and increased LNA titers in both lavage fluids and serum following the SC dose of killed bacteria.

IgG

IgG

IgA

LNA


Input: Recent investigations have shown that Grenz rays can suppress the allergic contact dermatitis reaction completely and that Langerhans cells, identified by OKT6 antibodies and electron microscopy, disappear from the epidermis at the same time.

OKT6 antibodies


Input: The elements responsible for glucocorticoid stimulation of ADH gene transcription appear to reside outside of this region.

ADH gene


Input: The present studies compare the biochemical characteristics, Kanagawa hemolysin reactions, and plasmid profiles of 13 patient and 221 environmental isolates of the organism.

hemolysin


Input: High values of both retinol and beta-carotene were found in full fat cheeses and whipping cream: from 179. 0 (cheese, Edam-type) to 318. 7 micrograms/100 g (whipping cream) and from 86. 7 (cheese, Edam-type) to 186. 5 micrograms/100 g (whipping cream) for all-trans retinol and total beta-carotene, respectively.


Input: COGLAB includes measures of preattentional, attentional, conceptual, and psychomotor performance.


Input: With respect to effective diffusivity of platelets (De) and the surface reactivity constant (K), less significant differences were found among artificial materials.


Input: The two most recent patients (35 and 132 days) received only oral dipyridamole (75 mg X 3/day) and aspirin (80 mg/day) after the early recovery period (four-six days), resulting in normal prothrombin and partial thromboplastin times.

prothrombin

thromboplastin


Input: Middle-latency auditory evoked potentials (MAEPs) were recorded in controls and patients with focal lesions in dorsolateral prefrontal cortex.


Input: Specifically, they were performed to determine whether detection of envelope phase disparity was consistent with processing within a single channel in which the AM tones were simply added.


Input: Gel retardation assays combined with DNase I footprinting and diethyl pyrocarbonate interference showed that a nuclear factor from differentiated C2 myotubes and BC3H1 myocytes recognized a conserved A + T-rich sequence within the peripheral activating region.

DNase I


Input: Such transgenic plants should enable not only the mutational analysis of sequence elements within the replication origin region, but also the construction of a new generation of vectors for gene amplification in plants, based on a minimal virus replicon.


Input: Ventral rhinotomy is no more difficult than dorsal rhinotomy, has less patient morbidity and fewer postoperative complications, and is more cosmetically acceptable.


Input: Four full-thickness skin incisions were made in the back of 10 female pigs that treated twice a day for 14 days with 2 ml of epidermal growth factor (300 ng/ml) or 2 ml of Ringer' s lactate solution in a single-blind, randomized fashion.

epidermal growth factor


Input: During challenge, rebiopsy was done when reticulin antibodies turned positive (mean 0. 6 years, range 0. 2-2. 0) or at the end of the two year study.

reticulin antibodies


Input: The effect of iron intake on 59Fe absorption throughout pregnancy, and on maternal and fetal Fe status towards the end of pregnancy, was investigated in rats.


Input: The deduced protein sequence is characterized by a putative 16-residue amino-terminal signal peptide that is cleaved, resulting in a 239-residue polypeptide.


Input: Analysis of the rate constants indicated that the isomerization rate k12 was approximately equal to the apparent degradation rate of the delta 3 ester kdeg, and slower than the hydrolysis rate of the delta 2 ester k24.


Input: A protocol is elaborated for the preparation and characterization of a quality control material (QCM) containing intrinsic concentration of cadmium (Cd) (0. 8 microgram/L) and lead (Pb) (13. 4 micrograms/dL) from bovine blood and an elevated QCM containing Cd (5. 0 micrograms/L), mercury (Hg) (11. 2 micrograms/L), and Pb (34. 5 micrograms/dL) from bovine blood spiked with aqueous spiking-solutions prepared with salts of Cd, Hg, and Pb.


Input: Reagent strips are frequently used in the practice of laboratory medicine as well as outside the professional laboratories.


Input: Precipitating antibodies for Thermophilic actinomycetes and M. f. were negative.


Input: LON-72 (34 isolates), LON-73 (1), LON-71 (2) and LON-10 (2) were found at altitudes around 2000 m, 3 of them in a single village.


Input: Animal experimental and clinical applications of plates, screws and spinal segmental replacement implants made of this composite material have shown good results so far.


Input: Significance of delta-aminolevulinic acid analysis in clinical tests


Input: No changes were evident in the FR-task performance of controls that received daily saline injections.


Input: Although the fertility decline in the black population in the Mississippi Delta between the late 1870' s and early 1930' s closely paralleled that of the national black population, it rose much more dramatically in the 1940' s and 1950' s to almost 1880 levels.


Input: According to their staining affinity for anti-T antibodies, the glandular tissue cells were classified as T-, T +, T + +, and T and the annual changes in the numbers of these cell populations, as well as in the volume occupied by the glandular tissue, were calculated.

anti-T antibodies

T

T

T

T


Input: Ampicillin (AMP) alone or with an aminoglycoside (AMI) was the treatment in 9 and 16 cases, respectively.


Input: Alkoxymetgyl-3, 4-dimethylpyridinium chlorides were synthetized by reacting 3, 4-dimethylpyridine with chloromethyl alkyl ethers, while 1-ethyloxymethyl-3-alkylthiomethylimidazolium chlorides were obtained in reactions of 1-ethyloxymethylimidazol with chloromethyl alkyl sulfides.


Input: We investigated the incidence of congenital color deficiency among Koreans by the use of H-R-R pseudoisochromatic plates.


Input: Eighty patients presenting to HGGM with non-Hodgkin' s lymphomas between 1962 and 1986, were reviewed.


Input: The relation between VE/VO2 and Q/VO2 showed a significant negative correlation (r =-0. 93, p less than 0. 01).


Input: Retrograde filling consists in sealing endodontics system directly at the apical zone after surgical approach.


Input: Collaborative study of Japanese Pharmacopoeia Heparin Sodium Reference Standard


Input: Serological studies at the early relapse stage of this disease showed increased serum ANA, IgA and IgM level with normal IgG and decrease of C3 and C4.

serum ANA

IgA

IgM

IgG


Input: The maximum stress due to the hygroscopic examination of the composite was 0. 74 kg/mm2 at equilibrium of the water absorbed of the composite.


Input: Ischemic heart disease evaluated by exercise stress thallium-201 myocardial scintigraphy: a comparison of SPECT and bull' s eye display


Input: Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum.

47-kilodalton major integral membrane immunogen of Treponema pallidum


Input: Potential consensus sequences for early and late regulatory elements were identified.


Input: Construction of a RIP1 deletion strain and isolation of temperature-sensitive mutants.


Input: These data suggest that hypocitraturia in type I renal tubular acidosis may be due to a defect in proximal tubule function.


Input: Concomitant chronic lymphocytic leukemia, acute myeloid leukemia, and thrombosis with protein C deficiency.

protein C


Input: Vivid visual hallucinations without other psychopathology have been reported for several hundred years.


Input: In the whole group, basal GH and somatomedin-C levels decreased from a mean (+/-standard error of the mean) of 52. 3 +/-12. 7 to 11. 1 +/-6. 3 ng/ml and from 7. 6 +/-0. 7 to 2. 5 +/-0. 5 U/ml, respectively.

GH

somatomedin-C


Input: Application of different criteria of cure revealed that 19 patients (66%) had basal GH levels below 5 ng/ml, 17 patients (59%) had normal somatomedin-C values, 16 patients (55%) had complete GH suppression (less than 1 ng/ml) during OGTT, and 13 patients (45%) met the above-mentioned criteria with disappearance of the paradoxical GH response to TRH/GnRH test.

GH

somatomedin-C

GH

GH

TRH

GnRH


Input: It suggests a sequence of surgical planning that can prevent them and also offers ways of dealing with the problems should they occur.


Input: In Rat-1a cells the expression of human c-jun mRNA was associated with the ability to clone in soft agarose and form tumors in nude mice.

human c-jun mRNA


Input: Furthermore, formation of foci of transformed RECs by the c-jun/ras combination was augmented 3-fold by the tumor promoter phorbol 12-tetradecanoate 13-acetate.

c-jun

ras


Input: Platelet activating factor was given in six doses at 15 minute intervals and airway response measured as change in partial expiratory flow at 30% of vital capacity (Vp30).

Platelet activating factor


Input: There was no significant correlation between baseline PC40 methacholine and the maximal fall in Vp30 after either the first (12 micrograms) or the second dose (24 micrograms) of platelet activating factor.

platelet activating factor


Input: Both BG and IRI concentrations during the OGTT were the lowest in body builders, medium in controls, and the highest in obese men.

IRI


Input: Although it is well known that calcium channel blockers can influence contraction of vascular smooth muscle, there is less knowledge on its effect on excitation contraction coupling in the endocrine glands and more specifically on insulin and glucagon release.

insulin

glucagon


Input: Many studies have pointed out the possibility of " masked " organic factors in erectile impotence, detectable only by means of laboratory investigations: mild hypogonadism, hyperprolactinemia, occlusions selectively located at the site of the sexual arteries, venous incompetence, subclinical neuropathies.


Input: The site-specific DNA inversion system Cin encoded by the bacteriophage P1 consists of a recombinase, two inverted crossing-over sites and a recombinational enhancer.

Cin

recombinase


Input: The terminator region supported termination of transcripts initiated by RNA polymerase I in vivo.

RNA polymerase I


Input: US-Doppler has recently gained attention as a noninvasive method for the functional evaluation of arteriovenous fistulas (FAV).


Input: Doppler echo in evaluating arteriovenous fistulae for dialysis


Input: Following the patients during a course of therapy with a selective vasodilator calcium antagonist, the beta-adrenergic reflex vasodilation became substantially attenuated but was preserved during a placebo course of therapy.


Input: Of 110 previously untreated patients who had entered the study of protocol TCL821, 96 were evaluable.


Input: There were 3/32 (9. 4 per cent) adverse reactions (ADRs), and one case each of nausea, dizziness and increased menstrual flow.


Input: More mRNA corresponding to nagB and nagA is detected than that corresponding to the distal genes, nagC and nagD.

nagB

nagA

nagC

nagD


Input: Tumor necrosis factor (TNF) is reported to cause a shock syndrome similar to that produced by endotoxin (LPS).

Tumor necrosis factor

TNF


Input: The p34. 8 gene has a strong codon usage bias which is strikingly different from that of the polyhedrin gene.

p34. 8 gene

polyhedrin gene


Input: Of the single-stranded DNA transformants, 65% resulted from replacement of the resident met2 mutation by the exogenous wild-type allele.

met2 mutation


Input: The results strongly support the notion that the OBF1-binding sites and the OBF1 protein are important for normal ARS function as an origin of replication.

OBF1-binding sites

OBF1 protein


Input: On the basis of S1 nuclease protection analysis of RNA preparations from several mouse tissues, both dhfr and divergent genes showed similar levels of expression but did show some specificity in start site utilization.

S1 nuclease

dhfr


Input: Four out of 10 patients showed clinical improvement according to Ritchie-Index, pain score, ESR and CRP.

CRP


Input: 62: 2491-2499, 1987).


Input: Survival rates for the original treatment group were 84. 5% and 57. 6% at 12 and 21 months, respectively; for the delayed treatment group, 78. 8% and 64. 6% at 12 and 21 months, respectively, and 78. 8% and 47. 5% at 12 and 21 months, respectively, for 77 subjects with AIDS and 93. 0% and 71. 8%, respectively, for 50 subjects with AIDS-related complex in the original treatment group.


Input: The products of genes ura10 and ura3 are proposed to participate in the channeling of orotidine monophosphate.


Input: After the application of RS 86, REM latency was shortened in all groups under investigation.


Input: Hybridization analysis showed that the size of the mRNA is about 1. 4 kilobases.


Input: Agranulocytosis treatment with rhGM-CSF


Input: The R. meliloti nifH promoter but not the K. pneumoniae nifH promoter showed sigma 54-dependent methylation protection of guanine residues at-14,-25 and-26, the most conserved nucleotides characteristic of sigma 54-dependent promoters.

R. meliloti nifH promoter

K. pneumoniae nifH promoter

sigma 54

sigma 54-dependent promoters


Input: Major clinical symptoms of the disease were defined in this group of patients.


Input: Routine clinical analysis revealed lower hematocrit and hemoglobin, and elevated BUN and alkaline phosphatase in the treated group.

hemoglobin

alkaline phosphatase


Input: To assess the health significance of the early renal changes after chronic exposure to cadmium, 23 workers removed from exposure because of the discovery of an increased urinary excretion of beta 2-microglobulin or retinol binding protein, or both, have been examined once a year for five years.

beta 2-microglobulin

retinol binding protein


Input: In order to study the structural and functional organization of the eukaryotic nucleolus, we have started to isolate and characterize nucleolar components of the yeast Saccharomyces cerevisiae.


Input: A transcription factor exclusion assay was used to show that the PCF1 mutation affects two distinct stages in transcription: one prior to and one after stable complex formation; and that these effects are mediated by a component of the stable complex.

PCF1 mutation


Input: Psychiatry and the skin.


Input: These adverse effects usually abate with time.


Input: The cytosolic glutathione S-transferases (GSTs, EC 2. 5. 1. 18) are a superfamily of dimeric isoenzymes which catalyze the conjugation of electrophilic substrates with glutathione.

glutathione S-transferases

GSTs

EC 2. 5. 1. 18


Input: Furthermore, the 3'-untranslated regions of pmGT10 display a marked degree of homology to the 3' region of the rat Yb1 gene, while this region of pmGT2 displays marked homology to the corresponding region of the rat Yb2 gene.

rat Yb1 gene

rat Yb2 gene


Input: Model IV: primary abutments with the lateral incisor and the second molar as secondary abutments.


Input: The incidence of fetal breathing movements (06. 00-10. 00 h) decreased with increasing gestational age while fetal arterial concentrations of plasma PGE increased significantly over the same period of gestation.


Input: During the first 3 min of recovery, plasma potassium fell rapidly in spite of nearly unchanged blood acidosis and significantly decreasing bicarbonate concentration.


Input: The present data also suggest that when compared to the systemic vascular bed, the pulmonary vascular bed is less responsive to bolus administration of ET-1.


Input: In comparison with normal pregnant women and normal non-pregnant women, women with PIH showed an increase in heart rate, suggesting an increased peripheral sympathetic tone, and an initial derangement in renal function as shown by the increase in serum uric acid and reduction in sodium excretion and total and fractional calcium excretion at any given level of sodium excretion.


Input: We have examined the role of two recombination-and repair-defective mutations, rad1 and rad52, on direct repeat recombination in transcriptionally active and inactive sequences.


Input: The encoded protein has a leader sequence of 27 amino acids.


Input: On the other hand, knowledge of the epidemiology of Parkinson' s disease is necessary in creating etiological hypotheses, since only hypotheses consistent with the epidemiological profile deserve careful testing.


Input: The stereoselectivity of drug action.


Input: Scotchbond 2 showed the least dye penetration but not statistically less than the XR bond/Silus Plus combination.


Input: A combination of cisplatin and 5-fluorouracil, both administered 4 days continuously as infusion, was assessed in advanced head and neck cancer.


Input: Diagnosis of primary sclerosing cholangitis in a blood donor with elevated serum alanine aminotransferase.

serum alanine aminotransferase


Input: When statistically analyzed in various subgroupings, the obtained average sedimentation coefficients and polydispersity profiles supported the following conclusions: (a) loss of proteoglycan aggregation and sedimentability is confirmed to be a primary sign of cartilage matrix degradation; (b) higher S values for proteoglycans of the high weight (HW)-bearing areas and lower values for those of the low weight (LW)-bearing areas were a typical finding in normal cartilage samples; (c) inversion of this pattern was indicative of matrix degradation, suggesting that the HW regions are more affected than the LW-bearing areas; (d) the average S value distribution across cartilage thickness tended to resemble the corresponding proteoglycan content versus distance from articular surface; and (e) the deepest cartilage layer had, in most cases, the smallest amount of aggregates while the highest average sedimentability was observed at the middle zone of the normal samples.


Input: End points measured were perioperative (30-day) myocardial infarction (MI) rate and death.


Input: The predicted molecular weight of the polyprotein encoded by ORF1 is 33 kilodaltons (kDa).


Input: Thus RV O2 demand fell when RC O2 supply was reduced, although a flow reserve was available.


Input: An alternative method of UKM is proposed based on collecting a small fraction of spent dialysate flow for 3 consecutive dialyses.


Input: Primer extension experiments indicated that the transcription initiation site mapped to a position on gene IV that was analogous to that reported for the structurally similar P-450e gene.

gene IV

P-450e gene


Input: Significantly, the polymerase chain reaction results demonstrated that gene IV transcripts were associated with hepatic polysome fractions, indicating their active utilization in this tissue.

gene IV transcripts


Input: Validation of the survey of work styles: a profile measure of the type A behaviour pattern.


Input: Only one ADR was related definitely to ciprofloxacin therapy.


Input: HIV infectiousness and the AIDS epidemic.


Input: From day 30 after turnout, the PFB-group had significantly lower serum pepsinogen levels, which reflects the low degree of abomasal damage in these animals.

serum pepsinogen


Input: The corresponding inhibition of acid phosphatase activity in control male and female guinea pigs was 15. 91% and 20. 33% respectively.

acid phosphatase


Input: Its clinical and histopathologic characteristics.


Input: Normocapnic (PACO2 = 40 mm Hg) ventilatory drive increased significantly (p less than 0. 05) in six subjects (Type 1 response) and decreased substantially in the others (Type 2 response); with hypercapnia, the changes in drive were attenuated in both groups.


Input: Fundus changes in (type II) mesangiocapillary glomerulonephritis simulating drusen: a histopathological report.


Input: Chronic dose effects of methyl parathion on nuthatches: cholinesterase and ptilochronology.

cholinesterase


Input: Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles.

HLA-B

HLA-C sequences

HLA-B alleles


Input: A method for determining optimal development conditions by summary oxygen consumption


Input: Men were more positive about their physical fitness than women.


Input: Handgrip dynamometry was also carried out in 249 of the patients.


Input: In cerebrospinal fluid, an ADA catalytic concentration above 0. 15 mu kat/L strongly suggests tuberculous meningitis in patients older than 7 years (sensitivity 1. 00, specificity 0. 99 and efficiency 0. 99).

ADA


Input: NERVTRACK contains 4000 anatomical data items arranged in a tree-like manner reflecting structural and functional relationships.


Input: Perfusion washout: increasing a microvascular free flap tolerance to ischemia.


Input: Similarly, the sequence of the U2 RNA region shown to be involved in pre-mRNA branchpoint recognition in yeast, and exactly conserved in metazoan U2 RNAs, was totally divergent in trypanosomes.

U2 RNA region

metazoan U2 RNAs


Input: It is striking that the active CHO spacer promoter violated the otherwise universal rule that metazoan RNA polymerase I promoters all have a G residue at position-16.

metazoan RNA polymerase I promoters


Input: Significant intergroup differences are highlighted for both selected dentoskeletal and soft tissue profile variables.


Input: The author provides a rationale for an interactional view and presents a case in which post-surgical hiccups were successfully treated, using principles developed by the Mental Research Institute.


Input: The relative toxicity of nickel oxide (NiO), nickel sulfate hexahydrate (NiSO4. 6H2O), and nickel subsulfide (Ni3S2) was studied in F344/N rats and B6C3F1 mice after inhalation exposure for 6 hr/day, 5 days/week, for 13 weeks.


Input: Light microscopical and routine immunohistochemical studies of a cervical neoplasm in a 32 year old woman initially suggested a histiocytic lymphoma, but histochemical staining for chloroacetate esterase established the correct diagnosis.

chloroacetate esterase


Input: From the National Institutes of Health.


Input: Molecular cloning and characterisation of the two homologous genes coding for nitrate reductase in tobacco.

nitrate reductase in tobacco


Input: In the final model, grade (p = 0. 0002), peritoneal cytologic results (p = 0. 0002), progesterone receptor status (p = 0. 004), and age as a continuous variable (p = 0. 008) were most closely associated with disease-free survival.

progesterone receptor


Input: In contrast, despite external radiation therapy, brain metastases proved fatal.


Input: COUP transcription factor is a member of the steroid receptor superfamily.

COUP transcription factor

steroid receptor superfamily


Input: Cosmid clones containing both VNTR sequences were identified, and restriction mapping showed them to be less than 15 kb apart.


Input: The oxygen uptake (VO2), carbon dioxide output (VCO2), respiratory rate (fR), minute ventilation (VE), alveolar ventilation (VA), alveolar oxygen pressure (PAO2), and VE/VO2 ratio were higher in the cows, while the tidal volume (VT) and physiological dead space (VD) were larger in the horses.


Input: Epithelial damage was not observed in any controls but was in all tissues exposed to SO2.


Input: The present study investigates whether prostaglandins " cytoprotect " the gastric mucosa against hemorrhage-induced stress ulceration by assessing the influence of 16, 16-dimethyl prostaglandin E2 (16, 16-dm PGE2) on gross and microscopic lesion formation, intramucosal tissue pH, H + back-diffusion, and mucosal blood flow in rat gastric mucosa exposed to luminal acid (100 mM HCl) during hemorrhagic shock (13 ml/kg for 20 min).


Input: Transcripts characterized include (i) abundant monocistronic L11e and tricistronic L1e-L10e-L12e transcripts; (ii) less abundant bicistronic NAB-L11e and monocistronic NAB transcripts and (iii) a very rare ORF monocistronic transcript.

NAB

NAB transcripts


Input: Qualitatively, the results are similar for the two species: Both rhesus monkey and man have photopic and scotopic branches, which cross at approximately the same time in the dark and at approximately the same background luminance.


Input: At each level of PaO2 we obtained simultaneous measures of arterial and venous blood gases, venous lactate concentration, and changes in the relative concentrations of inorganic phosphate, phosphocreatine, and ATP measured with 31P magnetic resonance spectroscopy.


Input: Endometrial biopsies and plasma oestradiol (E2) and progesterone (P4) levels in 23 patients were evaluated during 26 replacement therapy cycles for premature ovarian failure.


Input: The mobility of the upper and lower premolars under load was investigated in relation to the interproximal contact and occlusal facets.


Input: This suggested that baboon liver class I ADH is of the same ancestral lineage as the human ADH-beta.

baboon liver class I ADH

human ADH-beta


Input: Each individual shot 25 bullets in about 5 minutes, at an intensity level calculated at 163 dB.


Input: Dynamic and static scintigrams, using 99mtechnetium methylene diphosphonate, were obtained at zero, six, and 12 weeks after fracture.


Input: On admission to our department in September, 1987, the patient was alert and had spastic paraparesis, the impairment of all sensory modalities below the level of Th 10 and urinary disturbance.


Input: Prostaglandins and gallstones