Input: In the 8 patients the difference betweent he mean diastolic values of delta PU and delta PM was-0. 54 +/-1. 0 (SD) mmHg.


Input: The biochemistry of amniotic fluid with poor fetal growth.


Input: Resistance to the simulated physiologic environment was tested by measured retention of mechanical properties after immersion times in pseudo-extracellular fluid (PECF) at 37 degrees C for as long as three years.


Input: This expression assumes: (1) a laminar flow regimen during expiration, and (2) a constant CT value over the range of VT.


Input: Their conduction velocity ranged from 0. 23 to 0. 98 m/sec (group C).


Input: The major urinary metabolites were 3-(3-carboxyphenyl)-5-hydroxymethyl-2-oxazolidinone and a glucuronide of toloxatone.


Input: The ventilation did not increase when PACO2 was increased.


Input: Changes of thirtynine serum protein components following surgical stress.


Input: These differences are smaller than those described in standard textbooks.


Input: The present study examined the dependence of difference tone level [L (f2-f1)] on the following parameters of the two-tone input: f1, f2/f1 (f2 greater than f1), L1, L2, and L1 = L2.


Input: With certain exceptions the method was considered suitable in the routine intravenous cholangiography.


Input: Delayed mortality of mice following inhalation of acute doses of CH2O, SO2Cl2, and Br2.


Input: Guinea pigs weighing 300 approximately 350 g were used.


Input: None of the cystometrograms showed uninhibited detrusor contractions.


Input: Treatment of Graves' disease.


Input: Allergic reaction to Patent Blue Violet during lymphography.


Input: One-third of the men with azoospermia and with sperm density of less than 10 million had marked FSH elevation and our experience confirms the work of others that this indicates a poor prognosis.

FSH


Input: It was concluded that both of these surgical procedures were as effective as pinealectomy in reversing the pineal-induced alterations in the reproductive physiology of the blind-anosmic female rat.


Input: This implies that the groups do not just differ along one dimension, but along three dimensions.


Input: Deep tans were induced over the backs of volunteers with repeated exposure to longwave ultraviolet radiation (UV-A).


Input: Elimination of bagassosis in Louisiana paper manufacturing plant workers.


Input: Evaluation of the Du Pont aca ammonia procedure.


Input: 2) The time-sharing principle was applied to gain high stability.


Input: In three of the seven, inhalation of 2 ml normal saline produced FEV1 falls of 25% to 30%, but these falls were not as great as each subject' s reactions to the test solutions.


Input: Potency of enflurane in dogs: comparison with halothane and isoflurane.


Input: Measurement of magnesium absorption in man using stable 26Mg as a tracer.


Input: Female mice were significantly more resistant to infection than males.


Input: During the following 9 1/2 years three sequential liver biopsies were performed.


Input: Thromboplastic and fibrynolytic activity of the blood after administration of intralipid in men with history of myocardial infarction up to 45 year of life


Input: The authors report the clinicopathologic findings in four cases of adult women with rhabdomyosarcomas that originated in the endometrium or cervix, or both.


Input: Urine antibodies could not be demonstrated in any other cases.


Input: 99mTc phytate, 198Au colloid, and 99mTc antimony sulfide have been used; the last appears to have been the most satisfactory.


Input: A suspected hypothalamic dysfunction and a slightly impaired pituitary function manifested as GH deficiency were their common endocrinological features.

GH


Input: A one-way analysis of variance, performed separately for men and women for differences among the three phobic groups on field dependence, showed significance (rho less than. 05) for the females, with the famale agoraphobic being more field dependent than the female simple phobic groups, but not for the males.


Input: Residues removed from transcripts by splicing were identified.


Input: The histochemistry and ultrastructure of calcified cerebellar deposits described by Tonge et al.


Input: A 36 year-old woman was given Ergotamine Tartrate 4. 5 mg p. d. during seven days, after an abortion (a still birth).


Input: As expected, the heparin did produce increased recalcification times and the development of occasional subcutaneous hematomas.


Input: The overall incidence of SIDS was 1. 43 per 1, 000 live births.


Input: Significant increases in mean serum E2 concentration (100 to 150 pg/ml) were noted at 6 and 8 hours after administration on day 1 and at 8 hours on day 4.


Input: We remain convinced that antilymphocyte globulin (ALG) is a potent immunosuppressive agent in humans.

antilymphocyte globulin

ALG


Input: Patients were subclassified into age-matched groups of primary untreated cancer (21), recurrent cancer (18), and " cured " patients who had been free of disease for at least 9 months (16).


Input: Bacteriostatic and bacteriacidal activity of hydroxy-9 ellipticine in vitro


Input: Personal satisfaction in nursing: an encounter with extremely hostile patients


Input: The effect of hydrostatic pressure on the swimming activity of three hyponeustonic crustacea, Anomalocera patersoni, Pontella mediterranea, Labidocera wollastoni


Input: Abnormal calcium metabolism in normocalcaemic sarcoidosis.


Input: A five-phase experiment was designed to investigate (a) whether contingent music-listening would act as a reinforcer to increase arithmetic performance of EMR children and (b) whether this contingent reinforcement would affect preference for that reinforcer.


Input: The responsiveness of visual cortex (VC) and superior colliculus (SC) was simultaneously compared following conditioning " ON " or " OFF " stimulation, in the rabbit.


Input: During activity III, one patient developed angina.


Input: Estimation of L-alanine in serum or plasma using the LKB reaction rate analyser.


Input: Infants who died in the first 12 hours from' IVH only' had suffered severe birth asphyxia but in those who died later the main symptom was recurrent apnoea.


Input: Wherever the site of the conditioning stimulation, these modifications disappeared after ischaemia of the leg.


Input: Near term, under experimental conditions, maternal and fetal blood gases, pH, uterine and umbilical blood flows were measured or calculated.


Input: It was concluded that patients with acute respiratory failure requiring artificial ventilation have two componenents of the pulmonary shunt, one parallel with and the other inversely related with the PAO2.


Input: The most common cause of renal deterioration in the spinal cord injured patient is irreversible vesicoureteral reflux.


Input: Circulatory arrest in the operating room.


Input: Iodine-123 was satisfactorily imaged only with the MEC and pinhole collimators, which in turn yielded MTF values comparable to those measured for 99mTc.


Input: Petrous meningioma en plaque presenting as a right middle ear tumor.


Input: The difficulties to analyse prostaglandins (PG) by gas-liquid chromatography are mainly due to the lack of sensitivity of the gas-chromatograph itself (higher than 200 ng) and to the poor resolution of the packed columns.


Input: Also, samples of serum were absorbed with the various solid-phase allergens and the reactivity of the remaining IgE antibodies was determined.

IgE antibodies


Input: Extramedullary plasmacytoma of the parotid gland


Input: The recovered calves were tested for immunity to homologous severe challenge, 50 or 73 days after the first infection.


Input: Oxygen tension of the small lymph vessels (PLO2) of the rabbit hind limb was measured with both a flow-through micro chamber and a polarographic catheter-tip oxygen electrode to obtain experimental data on the source of oxygen in the lymph.


Input: I.


Input: Since 1968, a steep decrease in the number of strains resistant to three or more antibiotics (multiple-resistant) and in strains of the 83A complex was noticed.


Input: The contraceptive pattern of 157 women was analysed and 13. 8 percent were using inefficient methods.


Input: I.


Input: Nerve stimulation (1. 5-12 cycles/s) produced frequency-dependent reductions in CBF, a decrease of 50 percent occurring with the highest frequency.


Input: Risk of infection in the treatment of fractures


Input: Prolonged heavy work effected an increase of 10. 3 plus or minus 0. 9 mmHg in in vivo P50 (7. 30 PH-v, 41 degrees C-v, and 45 Pv-CO2); due entirely to the additive effects of increased venous temperature and [H +].


Input: This sequence is almost identical with that of human luteinizing hormone (Sairam, M.

human luteinizing hormone


Input: At the very high dose levels used, sodium saccharin and sodium cyclamate were weak solitary carcinogens producing 4/253 and 3/228 bladder tumours respectively, and the first of these tumours did not appear for more than 80 weeks.


Input: However, a 10--15% lengthening of the partial thromboplastin time is evident after 24 hours of storage.

thromboplastin


Input: No evidence of either positive or negative chemography was found.


Input: A study of chromosomes of lymphocytes from patients treated with hycanthone.


Input: Study of the physico-chemical state of plutonium-239 in a citrate solution-blood system


Input: Maternal lactation


Input: In both cases, at the end of exposure the same level of blood carboxyhemoglobin (COHb) (about 50%) was reached.

blood carboxyhemoglobin

COHb


Input: The results indicate that increased pulmonary blood flow and decreased pulmonary vascular resistance with advancing gestation are due to an increase in the total number of vessels and increased vasomotor reactivity is related to an increase in the total amount of smooth muscle while the thickness of muscle in individual vessels remains constant.


Input: Reduction in dosage restored normal taste sense in all three, but in two the drug had to be discontinued because of persisting high transaminase levels.


Input: A late diagnosis of retinoblastoma is an unquestionable fact that allows its growth and leads to a deterioration in the outlook.


Input: The concept of " structural identifiability " is employed in this analysis to determine which model parameters can be and which cannot be determined " uniquely " from given input-output data; a step-by-step procedure based on an extension of this concept is presented for adapting the overall approach to the experimental design problem.


Input: Acquired factor VIII inhibitor in non-hemophilic patients

factor VIII


Input: The study of calcium metabolism in ten thalassaemic children comperatively with controls after oral administration of 47Ca has shown diminished intestinal absorption.


Input: AP was induced by intraductal infusion of two different concentrations of glycodeoxycholic acid (GDOC 17 mmol and 34 mmol).


Input: Tissue plasminogen activator, its inhibitor and other parameters of fibrinolysis in blood of patients operated for mild hypertrophy of the prostate

Tissue plasminogen activator


Input: The mean (+/-SD) PaO2 increased from 80. 8 +/-26. 9 mmHg before to 89. 8 +/-27. 3 mmHg after the infusion (P < 0. 05) and the PaCO2 decreased from 42. 4 +/-8. 3 to 39. 6 +/-7. 9 mmHg (P < 0. 05).


Input: The two drugs increase the rate of early diastolic filling.


Input: We cloned the third human gene for the LD78, termed LD78 gamma and the sequence analysis showed that it is a 5'-truncated pseudogene.

LD78 gamma


Input: In the absence of histological criteria, which it is difficult to demand in view of the variability of results and potential dangers of endomyocardial biopsy involving such thin and fragile ventricular walls, the diagnosis of ACRV is based upon the concomitant existence of: (1) electrophysiological criteria: ventricular arrhythmias, in particular sustained monomorphous VT, with the particular feature of a very high degree of sensitivity to adrenergic stimulation (exercise), the existence of late potentials on the high amplification ECG, a highly specific sign, though unfortunately of poor sensitivity in localized froms, those which are most difficult to identify (2); segmentary morphological and kinetic RV abnormalities, most often resulting in localized akinetic or dyskinetic parietal vaulting, with stasis " in situ ".


Input: 66: 469-479, 1992).


Input: Possibly, the scr1-1 mutation does not affect signal recognition or translational arrest but instead results in maintenance of translational arrest of AEP synthesis.

scr1-1 mutation

AEP


Input: Both Rep78 and Rep68 cut the terminal AAV sequence at the same site (nucleotide 124).


Input: Nucleotide sequence analysis revealed that TAR-binding protein is very similar to the CREB2 protein.

TAR-binding protein

CREB2 protein


Input: A patient suffering from heparin-associated thrombocytopenia (HAT), recurrent arteriothromboses, and acute renal failure after treatment with standard heparin is described.


Input: Comparison with the sequence databanks show that Tactile is a member of the immunoglobulin gene superfamily, with similarity to Drosophila amalgam, the melanoma Ag MUC-18, members of the carcinoembryonic Ag family, the poliovirus receptor, and the neural cell adhesion molecule.

Tactile

immunoglobulin gene superfamily

Drosophila amalgam

melanoma Ag MUC-18

carcinoembryonic Ag family

poliovirus receptor

neural cell adhesion molecule


Input: The phenotypes of the ICP0 nonsense mutants were intermediate between those of the wild-type virus and 7134 in that the more ICP0-coding sequence expressed by a given nonsense mutant, the more wild type-like was its phenotype.

ICP0-coding sequence


Input: In contrast, gel mobility shift experiments have failed to reveal that HAP2 or HAP3 binds to domain 1 or that hap3 mutations affect the complexes bound to it.


Input: The experiment results showed: (i) not only 1O2, but also free radicals (O2-.. OH and YHPD-.) can be formed by the aid of YHPD; and (ii) as to the ability of producing 1O2, YHPD less than BHPD, while for generating O2-. and. OH, YHPD greater than BHPD.


Input: Two points are indicated: first, the photosensitized damage of YHPD is interrelated to not only 1O2, but also free radicals (O2-.. OH and YHPD-.); second, although the photosensitized damage of YHPD is stronger than that of BHPD, yet the photosensitized damage is negatively correlated to the yield of 1O2 but positively correlated to those of O2-. and OH.


Input: The unphosphorylated form of RNA polymerase II is designated IIA, whereas the phosphorylated form is designated IIO.

RNA polymerase II


Input: RNA polymerase IIA was recovered in transcriptionally active complexes in reactions in which the input enzyme was RNA polymerase IIA.

RNA polymerase IIA

RNA polymerase IIA


Input: Fructokinase activity is elevated up to twofold when Z. mobilis was grown on fructose instead of glucose, and there was a parallel increase in frk mRNA levels.

Fructokinase

frk mRNA


Input: The enhancer region of Akv murine leukemia virus contains the sequence motif ACAGATGG.


Input: Two splice variants of ALF1 cDNA have been found, differing by a 72-bp insertion, coding for putative proteins of 682 and 706 amino acids.

ALF1 cDNA


Input: Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain.


Input: The-64/-37 region interacted with purified Sp1 and an unidentified protein (s), proximal regulatory factor (s) I (PRF-I).

proximal regulatory factor (s) I

PRF-I


Input: This soluble form of the HGFr (sHGFr) bound HGF with an affinity similar to that of the authentic, membrane-associated receptor.

HGFr

sHGFr

HGF


Input: Also, the human glycoprotein alpha-subunit promoter was induced 10-fold by FSK in GH4 rat pituitary cells. (ABSTRACT TRUNCATED AT 400 WORDS)

human glycoprotein alpha-subunit promoter

FSK


Input: Some research studies have related this kind of tumors with prolonged ingestion of H2 inhibitors and others antacid.


Input: The rationale for continuous dopaminergic stimulation in patients with Parkinson' s disease.


Input: Amino acid sequence comparison revealed significant homology between the yeast and Escherichia coli gamma-glutamyl kinases throughout their lengths.

yeast and Escherichia coli gamma-glutamyl kinases


Input: This computation is performed by a parallel network of locally connected neuron-like elements.


Input: Neither gene possesses a distinct transcriptional start site as shown by nuclease S1 analysis.

nuclease S1


Input: Gene and pseudogene of the mouse cation-dependent mannose 6-phosphate receptor.

mannose 6-phosphate receptor


Input: The chick axon-associated surface glycoprotein neurofascin is implicated in axonal growth and fasciculation as revealed by antibody perturbation experiments.

neurofascin


Input: Entry of yeast cells into the mitotic cell cycle (Start) involves a form of the CDC28 kinase that associates with G1-specific cyclins encoded by CLN1 and CLN2 (ref.

CDC28 kinase

cyclins


Input: From all clinically important yeasts species, a total of 96% were identified by ATB method according to conventional methods.


Input: Consequently, significant differences between the measured and calculated methods were noted in oxygen uptake (213 +/-41 ml/min vs 193 +/-25 ml/min, p < 0. 001), oxygen delivery (780 +/-297 ml/min vs 716 +/-296 ml/min, p < 0. 001), and cardiac output (5. 8 +/-2. 2 L/min vs 5. 3 +/-1. 8 L/min, p < 0. 001).


Input: Negatively supercoiled plasmid pUC19 did not compete, whereas an otherwise identical plasmid pUC19 (CG), which contained a (dG-dC) 7 segment in the Z-form was an excellent competitor.


Input: In contrast, the lumenal domains of Sec12p, Stl1p and Stl2p are very different in size and do not show any appreciable homology.


Input: The gene sequence also identified a 340-nucleotide RNA in total yeast RNA and in purified RNase MRP enzyme preparations.

RNase MRP enzyme


Input: The RNase MRP RNA gene was deleted by insertional replacement and found to be essential for cellular viability, indicating a critical nuclear role for RNase MRP.

RNase MRP RNA gene

RNase MRP


Input: Mutational analysis of essential IncP alpha plasmid transfer genes traF and traG and involvement of traF in phage sensitivity.

traF

traG

traF


Input: The promoter was stimulated 8-20-fold by phorbol esters accounting for the previously observed transcriptional activation of protein kinase C beta.

protein kinase C beta


Input: In the eight patients with persistent generalized lymph-adenopathy (PGL) and nontender, nonenlarging nodes, pathologic analysis revealed lymphoid hyperplasia.


Input: We found that both the E26 virus-encoded v-ets and the myeloid/B-cell-specific factor PU. 1 bind efficiently to this site in vitro.

v-ets

myeloid/B-cell-specific factor PU. 1


Input: Localization of the brachial plexus with the nerve stimulator is equally effective at the interscalene, supraclavicular, and axillary sites.


Input: The second method, the " macro " assay, has a sensitivity range of 0. 03-5. 0 micrograms phosphorus with 100-500 microliters HClO4.


Input: Anti-CRK antibodies detect a 53kDa protein in extracts of C. fasciculata in agreement with the size predicted from the nucleotide sequence of the cloned gene.

Anti-CRK antibodies


Input: Use of free-access minerals.


Input: Respiratory interaction after spinal anesthesia and sedation with midazolam.


Input: V.


Input: Rice dwarf phytoreovirus segment S12 transcript is tricistronic in vitro.

Rice dwarf phytoreovirus segment S12 transcript


Input: Cold cardioplegia was administered at 45 mm Hg every 20 minutes for 2 hours.


Input: Comparable amounts of alpha 5 beta 1 integrin were isolated from these cells by chromatography of detergent extracts on a fibronectin cell-binding fragment affinity column and elution with EDTA.

alpha 5 beta 1 integrin

fibronectin


Input: From this library, LEU2 and HIS3 cDNAs were recovered at a frequency of about 1 in 10 (4) and in 12 out of 13 cases these were expressed in a galactose-dependent manner.


Input: Among these, ACT1 was isolated four times, and NSR1 three times.


Input: BiP670 retains basal and Ca2 + ionophore A23187-inducible activities.


Input: As a part of a large examination, total and free serum cholesterol, total lipid and triglyceride levels were determined.


Input: DIBA was more sensitive and had a better negative predictive value and a lower false negative percentage than DFAT.


Input: Caries and parodontitis have been one of the most spread diseases of mankind.


Input: ME1a1, a 16-base-pair nuclear factor binding site residing between the c-MYC P1 and P2 transcription initiation sites, is required for P2 activity.

c-MYC P1 and P2 transcription initiation sites


Input: The next twenty years of prevention in Indian country: visionary, complex, and practical.


Input: The cDNA has an open reading frame of 900 amino acids capable of encoding a 97-kDa protein.


Input: The gene encoding TRP-2 maps to mouse chromosome 14, in the region of the coat colour mutation slaty.

coat colour mutation slaty


Input: A comparison of the amino acid sequence of the T. thermophilus enzyme with that of the Escherichia coli enzyme showed (i) a 37% overall similarity; (ii) the conservation of the Ser residue, which is known to be phosphorylated in the E. coli enzyme, and of the surrounding sequence; and (iii) the presence of 141 extra residues at the C terminus of the T. thermophilus enzyme.


Input: Because single-chamber rate-adaptive atrial pacing leaves the patient exposed to the risk of future development of AV block and DDD pacing does not provide chronotropic support, it is likely that the new rate-adaptive dual-chamber (DDDR) devices will be used in a significant number of these patients. (ABSTRACT TRUNCATED AT 250 WORDS)


Input: When transiently transfected into K562 cells, this Lg genomic clone is actively transcribed, suggesting that, although it possesses the characteristics of a processed pseudogene, it is likely to correspond to the gene encoding this new ferritin subunit.

Lg

ferritin subunit


Input: The p130 and p62 tyrosine-phosphorylated proteins that complexed v-Src SH2 in vitro also associated with v-Src in v-src-transformed Rat-2 cells; this in vivo binding was dependent on the v-Src SH2 domain.

v-Src SH2

v-Src

v-src

v-Src SH2


Input: These data support a possible biological significance of the frameshift to occur at this position of the large overlap by including the putative RNA template-binding site of the PLRV replicase in the ORF2a/ORF2b transframe protein.

PLRV replicase

ORF2a/ORF2b transframe protein


Input: The MET4 gene was cloned, and its sequence reveals that it encodes a protein related to the family of the bZIP transcriptional activators.

bZIP transcriptional activators


Input: It is believed that these domains are important for directing specific protein-protein interactions necessary for the proper functioning of Src.

Src


Input: The recently developed gamma-interferon (IFN-gamma) assay system for the diagnosis of bovine tuberculosis in cattle has been accredited by the Standing Committee on Agriculture for use in Australia.

gamma-interferon

IFN-gamma


Input: Control Tmuscle was 35. 8 +/-0. 7 degrees C, with control Wi, max being 51. 6 (SD 8. 7) W. kg-1.


Input: However, other regions of the plasmid are also efficiently repaired.


Input: Thus, the human D1A gene belongs to the category of tissue-specific, regulated genes that have housekeeping-type promoters.

human D1A gene


Input: Computer-aided " FRAME " analysis revealed four possible open reading frames (ORFs), three in one direction and one in the opposite direction.


Input: Domain II is highly homologous to the LDL receptor and contains four repeats with perfect conservation of all 6 consecutive cysteines.

LDL receptor


Input: Here, we present evidence for a model in which mRNA sequences up to around 100 nucleotides downstream from the start codon of 21K fold back and base-pair to the 21K translation initiation region, thereby decreasing the translation initiation frequency.


Input: In the last 20 years, the therapeutic uses of botulinum toxin, a potent neurotoxin, have been investigated.

botulinum toxin


Input: At the C-terminus of the protein is a domain that contains sequences very similar to those found in the breakpoint cluster region gene product, n-chimerin, and rho GAP, all of which have been shown to possess intrinsic GAP activity on small GTPases.

n-chimerin

rho GAP

GAP

small GTPases


Input: The circadian rhythmicity of sleep was pronounced.


Input: The sequence data now permit a detailed interpretation of the X-ray crystallographic structure of the enzyme and the cloning and expression of the clostridial gene will facilitate site-directed mutagenesis.


Input: AgMNPV and Orgyia pseudotsugata MNPV (OpMNPV) are similar in terms of promoter structure and polyhedrin primary sequence, and the polyhedrin gene of both viruses is transcribed in the anti-clockwise direction in relation to their physical maps.

polyhedrin primary sequence

polyhedrin gene


Input: These results are consistent with the roles that CCK and trypsin inhibitors are believed to play in the negative feedback control of pancreatic exocrine function.

CCK

trypsin


Input: A 724-bp segment of the 5'-flanking region consisting of the proximal E-box flanked upstream by a mammalian-specific 352-bp region was sufficient for maximal transcriptional activation in postconfluent BC3H1 myoblasts.


Input: These results indicate that baculovirus-expressed TR mediates transcriptional activation and repression in a promoter-specific manner in vitro.

TR


Input: The serum erythropoietin (EPO) concentrations of 15 male triathletes (26. 3 U. ml-1) were significantly lower than those of 45 male distance runners (31. 6 U. ml-1; P less than 0. 05).

erythropoietin

EPO


Input: These results support the diagnostic validity of NFPD in CP/NCA patients, because such patients had a family history of panic disorder similar to patients with a more classical panic disorder presentation.


Input: FDA regulations for growth factors and related products.


Input: DESIGN: Serum aldosterone and plasma renin activity were measured supine prior to and 60, 90, 120 minutes after oral captopril, 25 mg.

plasma renin


Input: Both parents are clinically normal and unrelated.


Input: UF-021 ophthalmic solution (0. 03 to 0. 24%), when topically applied to the eyes of rabbits, caused dose-dependent IOP reduction (2. 8 to 5. 2 mmHg), without transient IOP rise.


Input: This is in contrast with the classical' oxygen debt hypothesis', which states that the oxygen debt and lactate clearance are linked.


Input: In addition a greater proportion of women in the sweeping group had a cervical dilatation of 4 cm or more at the first vaginal examination in the labour ward (16/33 (49%) vs 5/32 (16%); OR 4. 39; 95% CI 1. 56 to 12. 32; P = 0. 005).


Input: A control group of nine women (age 23-40 years) on oral contraceptives (Nordette-28) was also studied four times during a pill cycle.


Input: Patients with an enzymatic activity below X--1 manifested a decrease of the content of IgA, IgG, IgM, T and B lymphocytes, and of phagocytic activity of neutrophils as compared to patients exhibiting a high enzymatic activity.

IgA

IgG

IgM


Input: The relation between myocardial beta-adrenergic receptor and left ventricular (LV) function was studied in 10 patients, aged 41 to 61 years (average 51), with LV volume overload mainly due to chronic mitral regurgitation.

myocardial beta-adrenergic receptor


Input: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

receptor tyrosine kinase


Input: The single most important element, by linker-scanning analysis, is a 10-bp region that contains a CCAAT motif.


Input: Capnography curves of 40 HVS patients, 40 non-HVS patients with psycho-somatic complaints and 26 healthy controls were analyzed.


Input: However, alterations in electrostatic and hydrophobic interactions created by the three amino acid substitutions prevent the conformational change in the enzyme usually produced by calmodulin binding.

calmodulin


Input: Transfer RNA genes from Dictyostelium discoideum are frequently associated with repetitive elements and contain consensus boxes in their 5' and 3'-flanking regions.


Input: Histamine-2 blockade in psoriasis


Input: A third is a partial element terminating at a probable internal restriction site used for cloning.


Input: No such benefits were seen for children with CD4 + counts below 0. 2 x 10 (9) per liter at entry.

CD4 +


Input: Because the human Antp TATAA binding protein is expressed in both lymphoid and non-lymphoid cells, we suggest that this homeobox gene has evolved a more general transcriptional regulatory function in higher eukaryotic cells.

human Antp TATAA binding protein

homeobox gene


Input: Venkatesan, and D.


Input: Stable expression of the chimeric alpha i (54)/s polypeptide in Chinese hamster ovary (CHO) cells constitutively increased both cAMP synthesis and cAMP-dependent protein kinase activity.

alpha i (54)/s

cAMP-dependent protein kinase


Input: Surprisingly, there is no sequence homology between this region of Ly-6E and the established consensus for the interferon-stimulated response element, which has been shown functionally important to all previously characterized alpha/beta interferon-inducible promoters.

interferon-stimulated response element

alpha/beta interferon


Input: Relatively large DNA rearrangements spanning the region with tandem direct repeats encoding the carboxy-terminal histone H1-like structure of AlgP were detected in several strains upon conversion from the mucoid to the nonmucoid phenotype.

histone H1-like

AlgP


Input: It is, however, extremely homologous to a third' non-classical' gene, HLA-5. 4, and to the chimpanzee gene, Ch28.

HLA-5. 4


Input: Although the N13-N20 interpeak interval remained stable because of the parallel shift of the 2 peaks, the central conduction time measured from onset latencies of N11 and N20 significantly increased.


Input: Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin.

statin


Input: Chem.


Input: This report substantiates that at least two of the 18 kDa hsps in maize are products of different but related genes.

hsps


Input: Finally, some point mutations in the Gag-Pol PR domain inhibited activation of RT in trans by a wild-type PR, suggesting that the correct conformation of the PR domain in Gag-Pol is prerequisite for activation of RT.

Gag

Pol

RT

PR

PR

Gag

Pol

RT


Input: Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation.

CDC2-related kinase

budding yeast cdc28


Input: E., Hession, C., Goff, D., Griffiths, B., Tizard, R., Newman, B., Chi-Rosso, G., and Lobb, R., (1990) Cell 63, 1349-1356).


Input: The above results mean that the increase in alpha-adrenergic receptors makes the prostate, which has been already hypertrophied, less elastic, inhibiting external urinary sphincter function.

alpha-adrenergic receptors


Input: An approximately 2-kilobase B2 transcript was expressed in all alfalfa organs tested.

2-kilobase B2 transcript


Input: In some early B cells and Abelson murine leukemia virus-transformed pre-B-cell lines, LT mRNA is constitutively expressed.

LT mRNA


Input: Testosterone, free testosterone, non-sex hormone-binding globulin-bound testosterone, and free androgen index: which testosterone measurement is most relevant to reproductive and sexual function in men with epilepsy?

non-sex hormone-binding globulin


Input: One patients had plasma C-peptide greater than 3 pM and was therefore excluded from analysis.

plasma C-peptide


Input: Complex repetitive discharges were observed in muscles of mdx mice but no complex repetitive discharges or other abnormalities were observed in muscles of normal control mice.


Input: W. G.


Input: A mouse brain beta-spectrin of cDNA was identified within a lambda Gt11 expression library using an antibody which specifically binds with the 235 kDa spectrin beta-subunit.

mouse brain beta-spectrin

235 kDa spectrin beta-subunit


Input: We obtained quantitative evidence on the coding of interaural time differences (ITDs) of click stimuli by 40 single neurons in the auditory cortex of anesthetized albino rats.


Input: Pulmonary hypertension, with or without coronary arterial narrowing, is the major condition leading to isolated atrial infarction.


Input: Diltiazem decreased the total body clearance from 34. 0 +/-8. 0 to 28. 6 +/-6. 1 mL/min (P less than. 01), and prolonged the elimination half-life from 12. 6 +/-3. 0 to 14. 3 +/-2. 5 hours (P less than. 01) of antipyrine without any changes in volume of distribution.


Input: The model is able to anticipate why the effect of water fluoridation on caries prevalence is most pronounced when caries is diagnosed at cavity level.


Input: An 8-h exposure to 10 mg DMEA/m3 corresponds to a postexposure plasma concentration and 2-h postexposure urinary excretion of 4. 9 mumol/l and 75 mmol/mol creatinine, respectively.


Input: Marked thrombocytopenia, depletion of serum fibrinogen and prolonged prothrombin and activated partial thromboplastin time, were recorded at 5 to 10 and 30 to 40 minutes after intravenous envenomation.

serum fibrinogen

prothrombin

thromboplastin


Input: Auditory threshold shifts, as measured by the auditory evoked brainstem response, were measured at 2, 4, 8, 12, 16, 20 and 24 kHz.


Input: Interspecific backcross analysis using progeny derived from matings of (C57BL/6J x Mus spretus) F1 x C57BL/6J mice indicates that the thrombospondin gene is tightly linked to the Fshb, Actcl, Ltk, and B2M loci on murine chromosome 2.

thrombospondin gene

Fshb

Actcl

Ltk

B2M loci


Input: If delay has occurred between centrifugation and the measurement, causing substantial loss of CO2, equilibration of the sample with a gas mixture corresponding to PCO2 = 5. 3 kPa prior to the measurement is recommended.


Input: The EPO levels were distinctly increased before transfusion; they did not significantly change just after transfusion, but subsequently decreased.

EPO


Input: Felodipine did not alter the baseline FEV1, but showed a small significant inhibitory effect upon histamine and AMP induced bronchoconstriction.


Input: Relatively little is known regarding the role of 5-HT2 receptor activity in male rat sexual behavior.

5-HT2 receptor


Input: The present study reports visual evoked potential responses to pattern reversal (VEP-P) in ten third trimester pregnant women and changes in latency of NPN complex when compared with these responses in the non pregnant state.


Input: In all instances the apparent alcohol responses were very small and never exceeded a reading of 1 microgram/100ml for breath samples more than 10min post-exposure.


Input: The gene is 1, 139 base pairs (bp) long, and, like other members of the SIG family, the beta TG gene is divided into 3 exons.

SIG family

beta TG gene


Input: Thus, the positive effect of NS1 on the steady-state levels of P4 transcripts depends on the amplification of gene copy number and the integrity of the terminal repeats.

P4 transcripts


Input: It is transparent, cheap to be made, and easy to empty and was tested in 118 animals for two and four weeks.


Input: The Thr161Val mutation causes a lethal phenotype in the fission yeast Schizosaccharomyces pombe, while replacement of Thr161 with glutamic acid, potentially mimicking phosphorylation, causes uncoordination of mitosis and multiple cytokinesis.


Input: Deregulation of their expression may contribute to malignant transformation associated with HTLV-1 infection.


Input: In conclusion, we observed a great regeneration ability following mechanical injury in the nasal mucosa.


Input: There occurred a linear relationship between the drop in glucose-6-phosphatase dehydrogenase activity and in vitamin E level, on one hand, and the duration of poisoning with sodium nitrite.

glucose-6-phosphatase dehydrogenase


Input: A vector containing a transcriptionally inactive neomycin phosphotransferase II gene was used to select promoter sequences from a pool of random genomic DNA fragments.

neomycin phosphotransferase II gene


Input: Previous analysis of the 98-bp sequence has delineated several protein-binding domains that are recognized by nuclear factors present in human brain cells.


Input: Naturally acquired antibodies were demonstrated in some rabbits kept on commercial farms.


Input: Biol.


Input: Nucleotide sequences between the env gene and the LTR of SFV-1 were determined.

env gene

LTR of SFV-1


Input: The human cDNA was used to demonstrate that tumor necrosis factor-alpha could rapidly stimulate MARCKS gene transcription in the human promyelocytic leukemia cell line HL60.

tumor necrosis factor-alpha

MARCKS gene


Input: Dd PK1 RNA decreases after 6 h of starvation to re-accumulate once the cells have aggregated.

Dd PK1 RNA


Input: Young CD-1 mice, 4 days old, exposed to 0. 1% nicotine sulfate on gestational days 6-20 were compared with untreated pups of the same age to determine its effect on the development of mandibular first molars.


Input: USF synthesized in an in vitro transcription and translation system also binds to the ADH promoter as well as to the MLP.

USF

ADH promoter


Input: Arterial radioactivity content after the intravenous administration of HMPAO in seven human subjects was analyzed.


Input: Linear regression analysis was performed and the following result was obtained: clearance (HMPAO) = 0. 07 + 0. 43. rCBF with a high significance (p less than 0. 001).


Input: Saccharomyces cerevisiae has been used widely both as a model system for unraveling the biochemical, genetic, and molecular details of gene expression and the secretion process, and as a host for the production of heterologous proteins of biotechnological interest.


Input: Formalin activated both SNO NS and NnS neurones, but, when they responded, NS neurones (n = 5) showed only the first phase of activity while NnS neurones showed either one (n = 13) or two phases (n = 6).


Input: Uptake of ofloxacin by Escherichia coli


Input: A deletion series of the 5' flanking region was created from position-1329 to-74 relative to the transcriptional initiation site and similarly examined in transgenic tobacco.


Input: Toxicity was very mild with both regimens, although sedation was significantly higher in arm B (p less than 0. 001).


Input: Limits of energy turnover in relation to physical performance were addressed in terms of upper and lower limit, changes during a training programme and how to regulate energy balance at a changing energy turnover.


Input: Moreover, promoters containing a TATA box in the absence of Sp1 sites or Sp1 sites in the absence of a TATA box were equally inducible in vitro, as was an RNA polymerase III promoter.

Sp1 sites

Sp1 sites

RNA polymerase III promoter


Input: Ivermectin uptake and distribution in the plasma and tissue of Sudanese and Mexican patients infected with Onchocerca volvulus.


Input: The currently proposed extended arch repair should be reserved for the small group of infants with transverse aortic arch to ascending aorta diameter ratios (arch indices) of less than 0. 25.


Input: DNA hybridization analysis revealed that both pigmented and nonpigmented cells of Y. pestis possess a DNA locus homologous to the Escherichia coli fur gene.

Escherichia coli fur gene


Input: We report two patients receiving maintenance valproate, one with resolving acute hepatitis C and the other with chronic persistent hepatitis C, with incidental microvesicular steatosis demonstrated on oil-red O stains.


Input: UDP-Gal: Gal beta 1----4GlcNAc alpha 1----3-galactosyltransferase is a terminal glycosyltransferase that is widely expressed in a variety of mammalian species, with the notable exception of man, apes, and Old World monkeys.

UDP-Gal: Gal beta 1----4GlcNAc alpha 1----3-galactosyltransferase

terminal glycosyltransferase


Input: A synthetic oligonucleotide containing the SRE sequence from the mouse c-fos gene promoter (-299 to-322) was radioactively labeled, used as a probe for the mobility shift assay and Southwestern (DNA-protein) blotting, and also used for sequence-specific affinity chromatography.

mouse c-fos gene promoter


Input: This study indicates that this dose-intense regimen can be safely administered, even with the use of purged marrow, with an acceptable toxicity profile.


Input: INTERVENTIONS: Patients received rt-PA, heparin, and aspirin.

rt-PA


Input: Sequence analysis of the sMtCK genomic upstream sequences reveals a typical TATAA box within the 80 base pairs (bp) that, by transfection experiments, are sufficient to promote expression of chimeric plasmids with the chloramphenicol acetyltransferase reporter.

sMtCK genomic upstream sequences

chloramphenicol acetyltransferase reporter


Input: Sequence analysis of the sMtCK genomic upstream sequences reveals a typical TATAA box within the 80 base pairs (bp) that, by transfection experiments, are sufficient to promote expression of chimeric plasmids with the chloramphenicol acetyltransferase reporter.

sMtCK genomic upstream sequences

chloramphenicol acetyltransferase reporter


Input: The cDNA segment is flanked by the immunoglobulin gene recombination signal sequences so that the cDNA segment can invert and the human IL-2R L chain is subsequently expressed under the control of the SV40 promoter.

immunoglobulin gene recombination signal sequences

human IL-2R L chain

SV40 promoter


Input: Habituation of completely isolated neurons of the edible snail to electrical stimulation.


Input: Insulin-like growth factor 1 (IGF-1) in burn patients.

Insulin-like growth factor 1


Input: The suppression was also demonstrated in a transient expression assay in vivo using isolated barley endosperms.


Input: RNA gel retardation and competition analyses indicate that TRP-185 binding is strongly dependent on the TAR RNA loop sequences.


Input: This generalization of MFP involves defining an appropriate high-resolution cost function, parametrizing the search space of the environment and source, constructing solutions of the wave equation, and utilizing a nonlinear optimization method to search the parameter landscape for the global minimum of the cost function.


Input: The original technique was developed in the 1960' s to analyze the inner ear fluid as a diagnostic procedure (i. e., diagnostic labyrinthotomy) in acoustic neuroma suspects.


Input: Evolution of lesions did not necessarily follow a regular progression through the later stages of the vitelliform classification.


Input: Urine specimens containing either phencyclidine (PCP) or 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (9-THC-COOH) were adulterated with sodium chloride, bleach, vinegar, potassium hydroxide, liquid soap, 2-propanol, and ammonia.


Input: Along with previously mapped genes including Ly-1 and CD20, OSBP defines a new conserved syntenic group on the long arm of chromosome 11 in the human and the proximal end of chromosome 19 in the mouse.

OSBP


Input: Here we show that these synthetic binding sites have a more restricted and specific ability to enhance transcription when assayed in transformed embryos.


Input: After base-line CBF was established, hexamethonium bromide (2 mg/kg iv), ipratropium bromide (0. 5 microgram/kg iv), indomethacin (2 mg/kg iv), or intravenous 0. 9% saline was administered.


Input: This study suggests that BSPMs are useful in the assessment of AMI in terms of diagnosis, location and extent of myocardial infarct.


Input: Examination of immediate-early transcription factor expression during the MDI regimen revealed that RA mediated an elevated, prolonged expression of c-Jun mRNA accompanied by diminished expression of c-Fos and Jun-B mRNAs.

immediate-early transcription factor

c-Jun mRNA

c-Fos

Jun-B mRNAs


Input: Although heart rate and diastolic pressure rose in some degree 1 min after intubation, free and total CA concentrations did not increase during study period.


Input: Processing, secretion, and immunoreactivity of carboxy terminally truncated dengue-2 virus envelope proteins expressed in insect cells by recombinant baculoviruses.

carboxy terminally truncated dengue-2 virus envelope proteins


Input: Seven clones encoding interferon response element binding factors have been isolated from a mouse fibroblast lambda gt11 cDNA library by using a 32P end-labeled tandem trimer of the mouse (2'-5') oligoadenylate synthetase gene interferon response element as a probe.

interferon response element binding factors

mouse (2'-5') oligoadenylate synthetase gene


Input: DNA-protein UV cross-linking studies indicated that UHF-1 has an electrophoretic mobility on sodium dodecyl sulfate-acrylamide gels of approximately 85 kDa and suggested that additional proteins, specific to each promoter, bind to each site.


Input: The specific interaction between a defined structural element of the human immunodeficiency virus mRNA (RRE, the Rev response element) and the virus-encoded protein Rev has been implicated in the regulation of the export of unspliced or singly spliced mRNA from the nucleus to the cytoplasm.

RRE

Rev response element

virus-encoded protein Rev


Input: Radiation-induced changes in the area of alveoli and septa as well as collagen content were seen 11 weeks after irradiation.

collagen


Input: The first follow-up was at a nearly constant interval of 5. 1 years in Caerphilly and 3. 2 years in Speedwell; 251 major IHD events had occurred.


Input: Once the proliferation of fibroblasts and collagen synthesis had led to an increase of mechanical strength, no negative effect on wound healing could be detected applying the same chemotherapeutic agents.

collagen


Input: During the years 1980-87 a total of 287 persons received disability pensions in the municipality of Nordreisa in northern Norway.


Input: HeLa and Jurkat cell lines carrying the nef gene linked to the CMV promoter or the HIV-1 LTR were isolated by coselection for neomycin resistance.

nef gene

HIV-1 LTR


Input: Two patients had immediate adverse effects from NMF; one had a grand mal seizure and the other developed severe abdominal pain.


Input: The muscles from the ischemic group had significantly lower (P less than. 05) values for capillary density and capillary to fiber ratio and significantly higher intercapillary distance than those from the normal group.


Input: Serum TNF concentrations were elevated at diagnosis and gradually decreased toward the reference limits by week 16.

Serum TNF


Input: Conclusion: inlet type VSD and perimembranous type TOF have anatomic features in which the proximal His bundle tends to be jeopardized by suturing for VSD closure.


Input: The remainder (18. 4%) was with IgA nephropathy, which was histologically mild.

IgA


Input: Grossly, the experimental vulvitis was identical to the field condition, and bacteria indistinguishable from the inoculated strains were reisolated.


Input: Hemorrhagic shock and bacterial translocation in a swine model.


Input: A method for establishing stimulus control of ethanol responding was developed.


Input: In all cases, high-level expression of the truncated avian integrins was obtained.

truncated avian integrins


Input: In adulthood these rats were hyperactive and learned the active avoidance response later than the controls.


Input: The N-terminal 115 amino acids correspond to a putative DNA-binding domain and show significant sequence similarity with other cloned IFN response factors (IRF-1 and IRF-2).

IFN response factors


Input: The patients were divided into 3 subgroups: 1) 13 N + patients with multiple hot spots (greater than 2) (N + IM); 2) 24 N + patients with single hot spots (less than or equal to 2) (N + IS); 3) 12 N-patients with single hot spots (less than or equal to 2) (N-IS).


Input: Further, they are consistent with the suggestion that sites homologous to the CAR1 URS may be situated in the 5'-flanking regions of multiple unrelated yeast genes.

CAR1 URS


Input: Uses of orthoclone OKT3 for prophylaxis of rejection and induction in initial nonfunction in kidney transplantation.


Input: Uses of orthoclone OKT3 for prophylaxis of rejection and induction in initial nonfunction in kidney transplantation.


Input: In Denmark only 1-3 cases of transfusion-associated hepatitis NANB (TAH-NANB) are registered annually or about 1 case per 100, 000 units transfused.


Input: Hence, the replacement of Phe-62 with Ser specifically affects a determinant on the lambda I light chain that is necessary for the intracellular transport of this molecule.

lambda I light chain


Input: The deduced amino acid sequence has the greatest homology (61%) to the green alga Scenedemus obliquus plastocyanin.

green alga Scenedemus obliquus plastocyanin


Input: Higher fasting serum gastrin concentration (102. 0 +/-21. 1 vs 63. 3 +/-8. 3 ng. l-1), and greater postprandial gastrin release (AUC0-120: 16690 +/-2648 vs 10654 +/-1283 ng. l-1 min) were observed after VTP-HM than after VTP-Cas.

gastrin

gastrin


Input: The experimental group consisted of 61 examinees class II/2 orthodontic anomalies.


Input: Subjects were 16 male chronic schizophrenics consisting of 8 DST suppressors and 8 nonsuppressors.


Input: In this article we propose to find out the percentage of normal occlusion and the distribution of maloclusions, according to the anteroposterior relationship between the dental archs (following the ANGLE3 classification).


Input: We have previously identified, by screening a lambda gt11 expression library, murine protein mXBP, which binds to a sequence which overlaps the 3' end of the murine class II major histocompatibility complex A alpha gene X box, a conserved transcription element found upstream of all class II genes.

murine protein mXBP

murine class II major histocompatibility complex A alpha gene X box


Input: A contiguous and sequentially occupied secondary Fur-binding site in entC was protected at higher Fur concentrations, extending the protected region to + 49, and sequestering the putative Shine-Dalgarno sequence.

Fur-binding site

entC

Fur


Input: The major promoter responds strongly to virus-encoded trans activators EIA and EIV and contains four elements: a TAGA motif analogous to the TATA box, two EIIF sites present in an inverted orientation, and an ATF/CREB site.

EIA

EIV

EIIF sites

ATF

CREB


Input: Luteinizing hormone-releasing hormone analog therapy of uterine fibroid: analysis of results obtained with buserelin administered intranasally and goserelin administered subcutaneously as a monthly depot.

Luteinizing hormone-releasing hormone


Input: Although there are no octamer elements in the adenovirus genome that are known to be important for transcription, there are octamer elements in the viral terminal repeat sequences.


Input: A 4. 8-kilobase BamHI-HindIII fragment encoding the entire Neurospora crassa CuZn superoxide dismutase gene (herein designated sod-1) was isolated from a genomic library using two 60-base deoxyoligonucleotide probes corresponding to the published N. crassa amino acid sequence.

BamHI

HindIII

entire Neurospora crassa CuZn superoxide dismutase gene


Input: Using appropriate synthetic HSE oligonucleotides, three types of clones with potential HSE binding domains were isolated from a tomato lambda gt11 expression library by DNA-ligand screening.


Input: This result indicates that separate complexes exist containing ankyrin and fodrin with either uvomorulin or Na +, K +-ATPase.

ankyrin

fodrin

uvomorulin

Na +, K +-ATPase


Input: These genes are expressed within a few hours of the initiation of development; their mRNAs accumulate to a peak at 12 hr and persist until culmination.


Input: In transient cotransfection assays using Chang liver cells (CCL 13), pM1 DNA exerts a 6-to 10-fold trans-activating effect on the expression of the pSV2CAT reporter plasmid.


Input: We have determined the nucleotide (nt) sequence of the 7. 5-kb COR segment that encompasses a cluster of six genes (CYC1, UTR1, UTR3, OSM1, tRNA (Gly) and RAD7) located on chromosome X of the yeast Saccharomyces cerevisiae.

7. 5-kb COR segment

tRNA (Gly)


Input: No recombination signal sequences have been found contiguous to the recombination point.


Input: The antinociceptive properties, as measured by the tail-flick and hot-plate tests, and the motor effects of an intrathecally-administered benzodiazepine agonist midazolam, alone, and in combination with morphine, was examined in rats.


Input: To identify these sites, the deduced amino acid sequence of the 3T3-L1 adipocyte insulin receptor of the mouse was determined.

adipocyte insulin receptor


Input: PAO blocks turnover of the phosphoryl group of pp15, causing its accumulation, and thereby appears to interrupt signal transmission from the receptor to the glucose-transport system.


Input: It is likely that the sequence similarities reflect a common molecular architecture of the two heme binding sites and of a copper binding site in these enzymes.


Input: The TraD protein (83, 899 Da) contains three hydrophobic regions, of which two are located near the amino-terminal region.

TraD protein (83, 899 Da)


Input: The protein product of orfD, which is probably a new tra gene (named traX), contains 65% hydrophobic amino acids, especially rich in alanine and leucine.

orfD

tra gene

traX


Input: A gene in Drosophila melanogaster that maps cytologically to 2C1-3 on the distal portion of the X-chromosome encodes a member of the steroid/thyroid hormone receptor superfamily.

steroid/thyroid hormone receptor superfamily


Input: A portion of Region II also resembles part of the human c-jun oncoprotein' s leucine zipper, which in turn, has been demonstrated to be the heterodimerization site between the jun and fos oncoproteins.

c-jun

jun

fos oncoproteins


Input: To determine whether vanadate could inhibit PEPCK gene transcription, a series of chimeric genes containing several deletions in the P-enolypyruvate carboxykinase promoter between-550 and-68 was linked to the structural genes for either amino-3-glycosyl phosphotransferase (neo) or chloramphenicol acetyltransferase and introduced into hepatoma cells using three methods: (a) infection with a Moloney murine leukemia virus-based retrovirus, (b) transfection and stable selection for neo expression, or (c) transient expression of chloroamphenicol acetyltransferase.

PEPCK gene

P-enolypyruvate carboxykinase promoter

amino-3-glycosyl phosphotransferase

neo

chloramphenicol acetyltransferase

neo

chloroamphenicol acetyltransferase


Input: Significant correlations were obtained between changes in SSEP in response to AS and the presence of not deep residual-organic disturbances, so-called " ground " in psychogenic disorders.


Input: Both strains grew very poorly, or not at all, on nonfermentable carbon sources and exhibited, at most, only 5% of wild-type ubiquinol-cytochrome c oxidoreductase activity.

wild-type ubiquinol-cytochrome c oxidoreductase


Input: Regulation of irgA by iron in V. cholerae occurs at the transcriptional level, and there is an interrupted dyad symmetric sequence in the vicinity of the promoter that is homologous to Fur binding sites of E. coli.

irgA

Fur binding sites


Input: The recombinant contains the normal beta A-globin gene, the mutant gene and Ylp vector sequences between the two copies.

beta A-globin gene


Input: The characterized Y' repeated sequence families provide an experimental system in which repeated sequence interactions and subsequent evolution can be studied.

Y' repeated sequence families


Input: However, primary transcripts of a variant tRNA (Val) (UAC) gene are processing deficient under standard growth conditions (30 degrees C), due to a slightly altered 5' flanking region.

variant tRNA (Val) (UAC) gene


Input: Three of the short ORFs in the central region of BIV have been identified by location and structural similarity to the nonstructural/regulatory genes (vif, tat, and rev) of other lentiviruses; we also discovered two unique ORFs, termed W and Y, which may serve as exons for novel genes.

vif

tat

rev


Input: The contribution that alternative splicing events in c-myb expression may make on c-myb function remains to be elucidated.

c-myb

c-myb


Input: IgG and IgM antibody activity was determined by adding a 1: 100 dilution of serum to plates coated with A60 antigen.

IgG

IgM

A60 antigen


Input: 1, among which nine have been cloned and two (potentially functional) sequenced.


Input: The urinary protein, serum albumin, BUN and SCr all had very significant improvement.

albumin


Input: Patients with detectable serum TNF levels had significantly lower serum T3 concentrations compared to those with undetectable levels [1. 072 +/-0. 588 vs.

TNF


Input: Rats with one olfactory bulb removed and the contralateral naris closed can detect odors.


Input: Expression of the human T cell receptor (TCR) alpha gene is regulated by a T cell-specific transcriptional enhancer that is located 4. 5 kilobases (kb) 3' to the C alpha gene segment.

T cell receptor (TCR) alpha gene

C alpha gene segment


Input: The Ets-1 binding site was localized to a 17-base pair (bp) region from the 3' end of T alpha 2.

Ets-1 binding site

T alpha 2


Input: Human T-cell leukemia virus type I (HTLV-I) encodes a 40-kDa nuclear protein, Tax, which stimulates transcription from three 21-base pair (bp) repeats in its U3 region.

Tax


Input: We have now identified, after 21 serial undiluted passages of MHV, a small DI RNA, DIssF, which is efficiently packaged into virions.

small DI RNA

DIssF


Input: This, together with the data obtained with haloperidol, suggests that a minimal increase in the firing rate of LC cells (+ 140%) is required before it could influence the turnover of NA, as measured by DOPAC changes.


Input: The Mauriceville and Varkud mitochondrial plasmids are closely related, closed-circular DNAs (3. 6 and 3. 7 kb, respectively) that have characteristics of mtDNA introns and retroid elements.


Input: The circadian rhythm, however, was not affected and the difference between minimum (12. 00 h) and maximum (18. 50 h) serum concentrations was 31. 3%.


Input: Most strains (95%) of S. lugdunensis produced a delta hemolysin like that seen with nine other species of CNS.

delta hemolysin


Input: Experiments showed that temporary arrest of pulmonary circulation under conditions of extracorporeal circulation is attended by the development of ischemia of the respiratory pulmonary tissue.


Input: Taste reactivity tests were used to examine the orofacial responses of alcohol preferring (P) rats and alcohol nonpreferring (NP) rats to the taste of alcohol.


Input: 1 (" long method ") and the HML method.


Input: No causal relations may be inferred from the correlation between the level of trapezius activity and complaints, though it indicates that individual, inexpedient muscle activity patterns may constitute an important risk factor for development of musculo-skeletal complaints.


Input: Analysis with additional anti-peptide antibodies specific for alpha, beta, or gamma PKC indicated that all three types of PKC are expressed in JK cells; however, JKPE cells lost a major approximately 82 kDa immunoreactive cytosolic protein detectable with anti-PKC alpha antibody.

alpha, beta, or gamma PKC

PKC

anti-PKC alpha antibody


Input: Erythrocyte protoporphyrin concentration increased significantly (P less than 0. 05) by 14 days in dogs fed the basal diet, and remained significantly high relative to that in dogs of the other dietary groups for the remainder of the study.


Input: The coding sequences of the Crry gene encompass over 25 kb of DNA, whereas the Crry-ps sequences are included within a single 5. 6-kb Eco-R1 fragment.

Crry gene

Crry

ps

5. 6-kb Eco-R1 fragment


Input: The genomic and transcriptional complexity of the Crry and Crry-ps genes.

Crry

Crry

ps


Input: Determination of three-dimensional imaging properties of a light microscope system.


Input: Methods used include Cobb angle and a segmental evaluation (T7-T12) of each of convex and concave rib-vertebra angles (RVAs), rib-vertebra angle differences (RVADs), vertebral rotation, tilt and displacement.


Input: Lars has AIDS--a more dignified life with care at home.


Input: Accumulations of Tl + 1 (202Tl label) were 6 times those for Ga or In in the brain and muscles, and. 1 times in plasma.


Input: A poor correlation was also observed between PbB and ALAD activity of the stearate workers.

ALAD


Input: Since the UfAP and UTMP share many biosynthetic and structural features that include site of biosynthesis in the endometrium, P4-responsiveness, the presence of the mannose 6-phosphate lysosomal recognition marker, and considerable sequence similarity, the UfAP and the UTMP may have homologous function which for both still remains obscure.

UfAP

UTMP

UfAP

UTMP


Input: Fifteen light for dates infants and their placentae were compared to 15 well-grown infants and their placentae.


Input: Treating renal anaemia with recombinant human erythropoietin.

erythropoietin


Input: Basing on experimental toxicity research it was established that, out of 50 atmosphere metal corrosion inhibitors, some 14 per cent were found extremely hazardous, 42 per cent--of high level hazardous, 33 percent--of moderate and 11 per cent--of low hazardous.


Input: The effects on reflex latencies but not on paCO2 or pHa were blocked by naloxone (2 mg/kg), and were not present in morphine-tolerant animals.


Input: Of the remaining seven, five reacted either with immediate and strong symptoms or had spontaneously reduced gluten intake, or had an acquired IgA deficiency.

gluten

IgA


Input: In addition serum IgE concentrations were not statistically different.

serum IgE


Input: The findings suggest that, although iodine deficiency is the most probable cause of goiter among immigrants of the 1928 cohort, where the native population is concerned (both men and women), some other goitrogenic factor (s) must be involved.


Input: Co-administration of 5FU, angiotensin II and microspheres via the hepatic artery may reduce drug exposure in the systemic compartment and therefore may increase the therapeutic ratio of 5FU administration via the hepatic artery.

angiotensin II


Input: In contrast, 2, 397 (74%) had one or more risk factors (not low risk); of these, 5. 3% died in 6 weeks (p less than 0. 001).


Input: Comparison of propofol and thiopentone as anaesthetic agents for electroconvulsive therapy.


Input: Nonvascular ophthalmic and neurologic disorders that can be confused with amaurosis fugax are listed, and an algorithm for evaluation (which includes ophthalmic examination, laboratory studies, and noninvasive carotid artery studies) is given.


Input: These characteristics of N22/P22 indicate that it is a localized synaptically dependent event conforming to a transverse dipole with dorsal negativity and a simultaneous anterior positivity.


Input: We evaluated the likelihood of tissues to be positive for carcinoembryonic antigen and the intensity of carcinoembryonic antigen staining in specimens of villous adenomas, mixed polypoid villous adenomas, polypoid adenomas, and diverticulitis using the peroxidase-antiperoxidase technique.

carcinoembryonic antigen

carcinoembryonic antigen

peroxidase

antiperoxidase


Input: These results support the view that clonidine and 6-OHDA, but not alpha-MD, have central pressor actions in the rat that oppose their antihypertensive action.


Input: We conclude that Hansel' s stain substantially improves the recognition of eosinophiluria as compared with Wright' s stain.


Input: The study included 139 eyes with presumed ocular histoplasmosis syndrome (POHS) and age-related macular degeneration (AMD).


Input: Rarely, patients with locally advanced, uncontrollable, non-metastatic prostatic cancer enjoy prolonged survival.


Input: ATP gamma S inhibition can be overcome by high concentrations of ATP, dATP, araATP, or ddATP.


Input: Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes.

alpha 1-fetoprotein gene


Input: The gene is contained within a 1. 8-kilobase AccI-EcoRI restriction fragment mapping at map coordinates 0. 136 to 0. 148 in the UL region of the EHV-1 genome and is transcribed from right to left.

AccI

EcoRI


Input: Spontaneous sensitization to cross-reacting chemicals in a proportion of control animals is strongly suggested, somewhat akin to spontaneous sensitization in patients with anaphylactoid reactions to neuromuscular blockers on first exposure, and in whom IgE antibodies are detected.

IgE antibodies


Input: The 84. 1C mAb recognizes a site on IgE which is identical or very close to the Fc epsilon R binding site, and 95. 3 recognizes a site on IgE which is related, but not identical to the Fc epsilon R binding site.

84. 1C mAb

IgE

Fc epsilon R binding site

IgE

Fc epsilon R binding site


Input: Endocrine cells were studied by means of Grimelius' silver staining and immunostaining for chromogranin, a general marker of endocrine cells.

chromogranin


Input: A potential TATA box is located 29 base pairs upstream of the first transcription initiation site.


Input: In 76% of 59 lead-toxic children, bone lead values measured by LXRF were equal to or greater than those measured in normal and industrially exposed adults.


Input: When considered with the known neurotoxic effects on children of " low levels " of exposure to lead, these results also suggest that either an excessively narrow margin of safety or insufficient safety is provided by present U. S. guidelines, which classify an elevated blood lead concentration as 25 micrograms/dl or greater.


Input: In resting 3T3 cells, jun-D is expressed at a higher level compared to c-jun and jun-B, and its transcription is stimulated only slightly by serum growth factors.

jun-D

c-jun

jun-B


Input: Functional rearranged antibody genes were detected with JH and VH heavy chain probes and with Jk and Vk light chain probes.

JH

VH heavy chain

Jk

Vk light chain


Input: Isolation of Weeksella virosa (formerly CDC group IIf) from a vaginal sample.


Input: Growth of tracheal anastomoses in growing animals


Input: The ORF1 product was required for competence, while ORF2, which was cotranscribed with ORF1 and encoded a predicted protein of 126 amino acids, was not.


Input: In all sessions under IFN, the latency of the P100 component of the VEP was shortened as compared to baseline conditions.

IFN


Input: This paper presents the reasons why countries to which Chagas disease is endemic should carry out the relevant research themselves.


Input: The PETCO2 measurement during precordial compression predicted the success of defibrillation with return of spontaneous circulation.


Input: Gastric CO2/HCO3 was determined in absence of simultaneous inhibition of acid secretion by intra-and extragastric pCO2/pH measurements in 23 persons and calculated using the equation of Henderson-Hasselbalch. pCO2 was measured with use of a new electrode.


Input: Inefficacy of phosphine fumigation against ticks.


Input: According to the published sequence of the CHS1 gene, this fragment contains four repeats of a TGAAACA consensus sequence previously identified in the alpha-factor-inducible BAR1 promoter [Kronstad, J.

CHS1 gene

alpha-factor

BAR1 promoter


Input: Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes.

Xenopus homolog of the mos protooncogene


Input: Southern blot analyses demonstrated a low, if not single, copy number for this gene and conservation of this domain in other vertebrates.


Input: We conclude that (a) the likelihood of detecting carcinoma or atypical hyperplasia exclusively in the adipose tissue component of grossly benign breast biopsies is extremely low, and (b) a possible cost-effective method of sampling grossly benign breast biopsies consists of initially submitting a maximum of 10 blocks of fibrous parenchyma for each case, then examining the remaining tissue histologically only if carcinoma or atypical hyperplasia is found among these blocks.


Input: A brief account of the 1988 seminar in Shanghai on viral hepatitis A


Input: Erythrocytic stages of mammalian malarial parasites contain acristate mitochondria whose functions are not well understood.


Input: Restriction maps of the cloned plasmids revealed that their chromosomal inserts consisted of overlapping fragments.


Input: In contrast, a similar fragment lacking the 38-base-pair region had no such stabilizing effect.


Input: This TC-II enhanson, which is identical to the kappa B motif from the kappa chain enhancer, was active in both lymphoid and non-lymphoid cells, which contrasts with the previously reported lymphoid cell specificity of the kappa B motif.

TC-II enhanson

kappa B motif

kappa chain enhancer

kappa B motif


Input: The DNA sequences predict proteins for SRP54sc and SRP54sp that are 47% and 52% identical to SRP54mam, respectively.


Input: Antihistamines in asthma.


Input: We have therefore evaluated the efficacy and safety of doxazosin, a new orally active selective alpha 1 blocker, in patients with systemic hypertension with concomitant airflow limitation.

alpha 1


Input: The discussion focuses primarily on the newer drugs like angiotensin converting enzyme inhibitors, alpha-adrenergic receptor blockers, and calcium antagonists.

angiotensin converting enzyme

alpha-adrenergic receptor


Input: A 736-bp sequence of the 5' flanking region adjacent to the cap site of the human AFP gene shows a 61% similarity with the corresponding region of the mouse AFP gene.

human AFP gene

mouse AFP gene


Input: Nodular involvement of the left lung and infiltration of the mucosa of the left lower lobe bronchus followed very gradually and a monoclonal gammopathy (IgA--Type Kappa) was demonstrated.

IgA--Type Kappa


Input: These data locate the aniridia gene (AN2) and a recurrent T-cell leukemia breakpoint (TCL2) in the marker sequence, on opposite sides of MIC1.

aniridia gene

T-cell leukemia breakpoint


Input: A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids.


Input: Most of them were situated at Sylvius fissure (13 cases).


Input: Intracellular activity studies indicated that, at ten times MBC, only penicillin had any significant activity against intracellular staphylococci, reducing survival by 28%.


Input: The lowest detectable concentration was 1. 0 ng/ml in the serum.


Input: The antigen-specific IgG4 antibody seems to be an index in evaluating immunotherapy objectively.

antigen-specific IgG4 antibody


Input: The differential diagnosis of both affections is based on the clinical course, sialography and CT examination which along with modern ATB treatment significantly modify hitherto used surgical therapy.


Input: An FP mutant, AcFP875-2, had a 1. 6-kbp insertion of S. frugiperda DNA near the 5' end of these transcripts which by S1 analysis were shown to initiate within the host cell sequence.

FP mutant


Input: Postcoital contraception: a family planning study.


Input: A 0. 5 rating was intended to characterize subjects in whom mild cognitive impairment due to senile dementia of the Alzheimer type was suspected but was insufficient in degree to warrant a diagnosis of definite dementia.


Input: An implant may release a drug either by diffusion concurrent with dissolution of the polymeric implant material without depolymerization (Type A) or by bioerosion involving depolymerization (Type B).


Input: Improved cosmesis, extension of the scope of the problems that can be addressed with this repair (including treatment of a distal urethrocutaneous fistula) and the ease with which the Arap procedure can be performed are the advantages that this operation has over other 1-stage distal hypospadias repairs.


Input: The galactose transporter shows both sequence and structural homology with a superfamily of sugar transporters which includes the human HepG2-erythrocyte and fetal muscle glucose transporters, the rat brain and liver glucose transporters, the Escherichia coli xylose and arabinose permeases, and the S. cerevisiae glucose, maltose, and galactose transporters.

galactose transporter

sugar transporters

human HepG2-erythrocyte and fetal muscle glucose transporters

rat brain and liver glucose transporters

Escherichia coli xylose and arabinose permeases

S. cerevisiae glucose, maltose, and galactose transporters


Input: The calcium requirement for hypothermic storage of the cardiac explant.


Input: The seventh cysteine residue of CTSE is located within the activation peptide region of the proenzyme.

CTSE


Input: With both wild-type and the mutant enzymes, ATP activates both [14C] Asp in equilibrium N-carbamyl-L-aspartate (C-Asp) and the [32P] carbamyl phosphate (C-P) in equilibrium Pi exchanges.


Input: Mapping results suggested that the complementation group identified by these mutants is allelic to the ag alpha 1 mutation identified previously.

ag alpha 1


Input: Recently, an alternatively spliced form of c-myb-encoded mRNA has been identified in murine cells containing either normal or rearranged c-myb genes.

c-myb-encoded mRNA

c-myb genes


Input: Metformin plasma concentrations remained unchanged except for patients transferred from 1. 5 to 2. 0 g daily to 850 mg twice daily; in these patients plasma concentrations increased from 1. 83 +/-0. 87 to 2. 50 +/-0. 89 micrograms/l (p less than 0. 01).


Input: A significant relationship existed during the evolution of the disease between CRS/BW and gas exchange parameters (FIO2 and a/AO2 ratio) (P less than 0. 01), but gas exchange improved earlier than lung mechanics.


Input: Liquid chromatography with amperometric detection (LC/AD) is used to determine fluazifop acid produced from the metabolism or base hydrolysis of fluazifop-butyl in soybeans and soybean oil.


Input: The dichloromethane is removed, mobile phase solvent is added, and aliquots are injected onto a PRP-1 liquid chromatographic column; fluazifop acid is separated from coextracted compounds and detected at an applied potential of + 1. 25 V, using an amperometric electrochemical detector in the oxidation mode.


Input: The titer of anti HSV type 1 and anti HSV type 2 antibodies in the mothers' and cord blood was determined and compared.

anti HSV type 1

anti HSV type 2 antibodies


Input: Kidney weight and kidney-to-body weight ratio were significantly elevated at the highest dose level after 10 weeks and at the two higher dose levels after 15 weeks of exposure.


Input: Swim-over: an alternative method for harvesting motile spermatozoa.


Input: A raised amplitude of the aggregation of plates and a decrease in the threshold of their sensitivity to ADP were established in the persons with types IIa and IIb HLP and in CHD without HLP.


Input: In Experiment 2, we again used classification, but the fixed standard 75 was not at the center of the range of target numbers (20, 21,...


Input: Among booked patients the maternal mortality rate was 0. 32 and among unbooked patients 11. 13 per 1000 deliveries.


Input: Evidence from the structure of a number of cDNA clones, as well as S1 nuclease and primer extension studies supports the hypothesis that the PTHrP gene contains at least two mRNA transcription start points that define two putative regulatory domains.

S1 nuclease

PTHrP gene


Input: The transcription initiation site was determined by S1 nuclease mapping.

S1 nuclease


Input: A larval albumin-like protein was not detectable by silver staining in serum of tadpoles before the beginning of metamorphosis at stage 48.

larval albumin-like protein


Input: Behaviorally, a pain-tolerant group (PT = 29 Ss) tolerated the entire 3-min test (means = 180 +/-0 sec), while a pain-sensitive group (PS = 13 Ss) averaged only 50. 31 +/-20. 81 sec of the cold-pressor test (t = 16. 75, P less than 0. 0001), replicating our earlier studies.


Input: Isolated proteinuria (i. e. without hematuria and/or pyuria) is a frequent finding.


Input: Lithium delays the circadian rhythm of wheel-running in Syrian hamsters at plasma concentrations (0. 59-0. 74 mM) that also cause toxic weight loss.


Input: When two-dimensional polyacrylamide gel electrophoretic patterns of [35S] methionine-labeled proteins secreted from cells infected with parental and recombinant viruses were compared, a spot missing from the latter corresponded in molecular weigh and isoelectric point with that predicted from the N1L ORF.

N1L ORF


Input: Buflomedil (i. v.) induced a dose-dependent increase of cardiac output at 0. 16-0. 64 mg/kg, biphasic changes at 1. 28 and 2. 56 mg/kg and a marked decrease and subsequent slight increase at a large dose of 5. 12 mg/kg.


Input: We use the term corticosteroid-dependent IA to refer to the serious problem of chronic IA requiring maintenance prednisone therapy.


Input: The two IL6 mRNA species are generated by alternative polyadenylation at sites separated by a distance of 1. 2 kilobases.

IL6 mRNA


Input: In one acromegalic patient visual improvement was obtained while the abnormal GH secretion remained unaltered.

GH


Input: In contrast, the PPSF + DBP side showed large amounts of bone formation, and bone almost covered the implant.


Input: In 44 evaluable patients the response rate was 50%, with one complete response.


Input: Thus, multiple myogenic factors that vary qualitatively and quantitatively may be responsible for the different and complex modulatory programs of actin gene expression observed during in vivo muscle differentiation.

actin gene


Input: The effect of acetazolamide (ACZ) on HCO3-and Cl-activities in inner ear fluid was investigated by ion-selective microelectrode methods.


Input: The predicted L mRNA was 6398 nucleotides long and contained a single open reading frame corresponding to an L protein encompassing 2109 amino acids with a MW of 241, 546.

L mRNA

L protein encompassing 2109 amino acids


Input: Aplastic crisis in sickle cell disorders: bone marrow necrosis and human parvovirus infection.


Input: The bactericidal activity of six new rifamycin derivatives--rifabutin (RBU), FCE 22250 (F22), rifapentine (RPE), CGP 29861 (C29), CGP 7040 (C70) and CGP 27557 (C27) and rifampicin (RMP)--have been measured against log phase and, as a better test of sterilising activity, against stationary phase cultures of Mycobacterium tuberculosis, H37Rv.


Input: Mo + SV M-MuLV-inoculated animals became moribund at 3 to 13 months postinoculation, whereas delta Mo + SV M-MuLV-inoculated animals became moribund at 6 to 24 months postinoculation.


Input: RVEF and LVEF both increased by about 14% (p less than 0. 05 and p less than 0. 01).


Input: The levels of NPY-ir in the rat vas deferens were not affected by either surgical or pharmacological treatment.

NPY


Input: The primary structure and cotranscription of the petCA genes encoding the Rieske-FeS (nuclear encoded in plants) and apocytochrome f proteins has been described previously (Kallas, T., Spiller, S., and Malkin, R.

petCA genes

Rieske-FeS

nuclear encoded in plants

apocytochrome f proteins


Input: The Nostoc petBD genes are not closely linked to the psbB gene (encoding the 51-kDa photosystem II polypeptide) and do not contain introns as do the closely related chloroplast genes.

petBD genes

psbB gene

photosystem II polypeptide


Input: RNA blot hybridizations identified an 1. 8-kb mRNA common to cytochrome b6 and subunit IV, and an intensely hybridizing 0. 8-kb mRNA specific to the subunit IV gene probe.

cytochrome b6


Input: All of the indigo-producing bacteria had an indoxyl phosphatase with a pI of 6. 4.

indoxyl phosphatase


Input: The number of polymerases active in vitro at the E strand promoter was similar to the number of polymerases at the L strand promoter.


Input: A family of RNA molecules in the 2. 0-2. 2-kilobase range identified with a probe from this gene was overexpressed in the resistant cells.


Input: Intravesical chemotherapy.


Input: Studies were performed on several superficial veins from the rabbit face to examine the relationship between beta adrenoceptor subtype distribution, intrinsic myogenic tone and sympathetic nerve innervation.

beta adrenoceptor subtype


Input: Two polyadenylation sites were used, one at the end of the early (E) region of the viral DNA, the other at the end of the late (L) region.

early (E) region

late (L) region


Input: We propose that the technique of low-frequency kindling is a useful experimental model in assessing the effects of antipsychotic or antiepileptic drugs on the excitability of the limbic regions.


Input: The biosynthesis and stability of the three mutant proteins were similar to those of the wild-type erbB protein, and all three retained the ability to transform chicken embryo fibroblasts.

wild-type erbB protein


Input: Codon usage in C. reinhardtii mitochondria is highly biased, with eight codons entirely absent from all protein-coding genes; however, even though codon usage is restricted, it appears that C. reinhardtii mtDNA cannot encode the minimum number of tRNAs needed to support mitochondrial protein synthesis.


Input: Like scrotal testes, undescended testes were hypointense to fat on sequences with a short repetition time (TR) and echo time (TE) in all cases, and hyperintense or isointense to fat on long TR/TE sequences in all but two cases.


Input: The East African dik-dik antelope represents a miniature model ruminant for comparative studies.


Input: Efficacy and field evaluation of Bacillus thuringiensis (H-14) and B. sphaericus against floodwater mosquitoes in California.


Input: 2 cases of type II tyrosinosis (Richner-Hanhart syndrome)


Input: This loss was independent of drug concentration and a correction factor was employed to calculate the true free diazepam concentration.


Input: Effects of a perfluorochemical blood substitute on diazepam binding by human albumin.

human albumin


Input: A second promoter activity was identified in the region between the two major transcriptional start sites.


Input: Computer analysis included digital averaging, followed by digital filtering in different frequency bands in order to determine the frequency range corresponding to notches and slurs.


Input: We also examined the relationship between the side of sinusitis and the cleft side in patients with unilateral cleft palate.


Input: Successful use of transureteroureterostomy to salvage ureterosigmoidostomy after anastomotic failure.


Input: We have identified and characterized the structure of the Spec1 gene in the sea urchin Strongylocentrotus purpuratus.

Spec1 gene


Input: Functional flow was evaluated using laser Doppler flowmetry (LDF), for which the output signal, blood cell flux (BCF), is expressed in terms of volts.


Input: Our data, however, did not suggest the existence of a conversion factor for LDF signal to absolute flow values from experiment to experiment.


Input: Quantitative analysis of the coronary stenosis was assessed before and after PTCA, and the dilatation resulted in an increase in minimal luminal cross-sectional area from 1. 1 +/-0. 8 to 2. 7 +/-1. 2 mm2.


Input: In a previous study (Brandl, C.


Input: The seco-steroid hormone 1, 25-dihydroxyvitamin D3 is known to induce the expression of a calcium binding protein termed calbindin-D28K in a variety of target tissues.


Input: In addition, the calbindin-D28K promoter is composed of a variety of simple repeated sequences, some of which are components of putative regulatory signals.

calbindin-D28K promoter


Input: Organ transplantation in Denmark.


Input: A 114-base pair sequence of predominantly repeating purine-pyrimidine nucleotides separates these two d (AC) repeats.


Input: Evidence for a role of endogenous corticotropin-releasing factor in cold, ether, immobilization, and traumatic stress.

endogenous corticotropin-releasing factor


Input: The 210 kDa precursor is converted slowly (t 1/2 = 2 h) by proteolytic processing into a 125 kDa (alpha') and 83 kDa (beta') species.


Input: Its predicted amino acid sequence shows extensive homology to those of Drosophila hsp70, trout hsp70, Xenopus hsp70, yeast hsp70, and some homology to the heat-inducible dnaK gene product of Escherichia coli.

Drosophila hsp70

trout hsp70

Xenopus hsp70

yeast hsp70

heat-inducible dnaK gene product


Input: At temperatures permissive for transformation, 6m2 cells contain P58gag produced from the 4. 0-kilobase (kb) viral RNA genome and P85gag-mos translated from a 3. 5-kb spliced mRNA.

mos


Input: Multistep transformation by defined fragments of herpes simplex virus type 2 DNA: oncogenic region and its gene product.


Input: One group (n = 9) was premedicated with midazolam, 0. 1 mg kg-1, and atropine 0. 2-0. 4 mg i. m.


Input: In order to study the influence of iron overload on the polymorphonuclear leucocyte (PMN) metabolism of patients on chronic hemodialysis, generation of superoxide anion (O2-) by PMN in whole blood was compared in two groups of hemodialyzed patients: group A consisted of twenty-one individuals with serum ferritin levels above 1000 ng/ml and group B of nineteen individuals with serum ferritin levels below 1000 ng/ml.

ferritin

ferritin


Input: Diazepam (3 mg/kg) generalized to Ro 11-6896 whereas the structurally related Ro 5-4864 (3 mg/kg and 30 mg/kg) did not.


Input: Five patients developed metastatic spread, and all of them died of tumor.


Input: There were no interfering peaks in the quantitation of sulbactam.


Input: Translation of specific cellular genes from the chimeric viral-cellular transcripts seems to be unlikely.


Input: Two mutants, each representative of a separate pet complementation group, have been analyzed.

pet


Input: A centromere in S. cerevisiae consists of a region of DNA, approximately 150 bp in length, containing three important sequence elements, which are folded with proteins into a specific conformation in the chromatin (the yeast kinetochore).


Input: Two separate NF1-binding loci were also found in the equivalent IE68 gene of HCMV (Towne) DNA, but in this case the DNA sequence and competition filter binding experiments indicated a maximum of only four to five consensus binding sites encompassing the promoter-enhancer region.

NF1-binding loci

IE68 gene


Input: The previously described four sets of 13-to 18-base-pair interspersed repeat elements between-55 and-580 provide most of the high basal transcriptional strength, whereas the arrangement of further upstream tandemly repeated NF1-binding sites may contribute significantly to the expanded biological host range for expression of SCMV IE94 compared with HCMV IE68.

NF1-binding sites

SCMV IE94

HCMV IE68


Input: Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines.

lambda and kappa antibody gene


Input: Influence of cyclo-oxygenase inhibition and of leukotriene receptor blockade on pulmonary vascular pressure/cardiac index relationships in hyperoxic and in hypoxic dogs.

cyclo-oxygenase

leukotriene receptor


Input: Northern analyses of RNAs from mouse tissues and cell lines indicated that p11 mRNA levels vary widely.

p11 mRNA


Input: Morphine produced a dose-dependent bradycardia followed by tachycardia.


Input: The PSS gene was subcloned into a 1. 1-kb fragment of the yeast DNA on the YEp13 vector.

PSS gene


Input: The gene is essential for yeast vegetative growth.


Input: Bacteriologic culture of pancreatic tissue was positive in 6/8 IB and 3/17 NIB rats (p less than 0. 01).


Input: These similarities suggest that these E2 proteins are structurally and evolutionarily related.

E2 proteins


Input: Histological examination revealed a small simple renal cyst associated with renal cell carcinoma.


Input: Thus, prostacyclin enhanced the autoregulative property of the inner ear vessels.


Input: The method is accurate, with good precision and adequate sensitivity.


Input: Factors influencing the bond strength between glass polyalkenoate (ionomer) cements and dentine.


Input: Van der Ende, R.


Input: Clinical findings were: height 183 cm, weight 62 kg, increased length of lower limbs, P2-A2 pilosity and micropenis.


Input: The 8 patients receiving Ir192 implant in addition to external radiation showed improved (p = 0. 06) survival compared to the 9 receiving external only: median 15 months (range 1. 5-34 + months) versus 7 months (range 2. 5-21 months).


Input: No effect was found on grooming behavior.


Input: Clinical and biological correlates of panic states.


Input: Effects of long-term parenteral nutrition on gastrin release in dogs.

gastrin


Input: The mean weight and height velocities were 148% and 122% of the standard, respectively.


Input: In 64% a small cardiac vein does not exist, but its origin, the right marginal vein, joins the system of anterior cardiac veins.


Input: The results of these experiments indicate that at least two upstream activator sequences (UAS) mediate maximum induction by galactose.


Input: Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments.


Input: The genetic basis for the expression of a latent VH allotype in the rabbit was investigated.

VH allotype


Input: Potentiation of the thrombolytic efficacy of single-chain urokinase (Pro-urokinase) by heparin.

single-chain urokinase

Pro-urokinase


Input: The variability is most likely a result of alternative splicing of exons from the primary elastin transcripts.

elastin transcripts


Input: This led to the conclusion that the metatarsal artery should be used for toe MP joint grafts, while the unilateral proper digital artery is suitable for toe PIP joint grafts, together with concomitant or dorsal cutaneous vein.


Input: Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

RNA polymerase II

TFIID


Input: You make the diagnosis.


Input: Conservative treatment of bladder carcinoma by partial cystectomy and interstitial iridium 192.


Input: The results presented suggest that TIQ reduces the turnover rate of the nigrostriatal dopamine neurons after repeated administration for a long period in mice.


Input: During a 28-week promotion bioassay, groups of 30 male CD-1 mice were treated once with 50 microliter of either DMBA (1. 0 mg/ml) or acetone, rested for 2 weeks, and then treated twice per week with test material for the remaining 25 weeks.


Input: An 11-month-old girl suffering from Dandy-Walker malformation (DWM) associated with tetralogy of Fallot (TOF) is presented.


Input: The median survival is not reached with a median follow-up time of 9. 6 years.


Input: Critical evaluation of various methods of determining markers of fetal maturity in amniotic fluid


Input: Neuromyelitis optica (Devic' s syndrome): not always multiple sclerosis.


Input: Effect of the methods of cutaneous administration of methyl isobutyl ketone on its toxicity


Input: The temporal and static plasma concentration-effect relationships were evaluated by pharmacodynamic modeling and linear regression.


Input: Fourteen patients were in the multifocal disease group; 13 were detected by SPECT and 10 by TCT.


Input: The SSB-poly (dT) affinity is too high to measure in buffers containing even 5 M NaCl; however, in 1. 8-2. 5 M NaBr, we measure alpha log Kobsd/alpha log [NaBr] =-5. 7 +/-0. 7, with a lower value of omega T/O = 130 +/-70.

SSB


Input: Minor differences were noted with latamoxef producing mild persistant elevation of prothrombin time (0. 7 second) associated with depression of factor II and factor VII.

prothrombin

factor II

factor VII


Input: Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone.

Plasma renin


Input: Cephradine 250 mg at night for 12 months was given as a prophylactic measure to 33 female patients of mean age 41. 6 years, who had a history in the preceding 12 months of between three and 24 (median = 7) episodes of frequency and/or dysuria.


Input: The activity of the EGF receptor promoter can be modulated by E1A protein and receptor RNA levels increased by stimulation with phorbol ester or fetal calf serum.

EGF receptor promoter

E1A protein


Input: By Felix Lagrange, 1918.


Input: The epidermal growth factor (EGF) receptor, which exhibits intrinsic protein tyrosine kinase activity, undergoes a rapid, intramolecular self-phosphorylation reaction following EGF activation.

epidermal growth factor (EGF) receptor

protein tyrosine kinase

EGF


Input: A case of AIDS-related complex (ARC/LAS) in a health worker


Input: Vimentin positivity was noted in the undifferentiated and fibroblastic components.

Vimentin


Input: The spermicide nonoxynol-9 is a member of a homologous series of alkylphenol-ethoxylates (polyethoxyethanols) of general formula C9H19-C6H6-O-(CH2CH2O) n-1 CH2CH2OH.


Input: Depending on the location and size of the mass, a wide range of clinical presentations is associated with the lesion.


Input: The development and distribution of Trypanosoma congolense, T vivax and T brucei in the skin of goats was examined after the animals were bitten by infected Glossina morsitans centralis.


Input: During the observation period of 0. 4-30 weeks, cardiac white spots on the right ventricle of BALB/c mice were first detected at three weeks (6 of 20 mice; 30%), and the maximal incidence of cardiac white spots was obtained at nine weeks (39 of 44 mice; 88%).


Input: Increasing the RH beyond 32% resulted in solvation of the peroxy radical, sterically hindering the radical from entering the propagation transition state.


Input: PATIENTS and METHODS: Thallium-201 myocardial scintigraphy was performed at rest and after 0. 56 mg/kg intravenous dipyridamole during four minutes in 16 patients with sarcoidosis.


Input: Which cineangiographically assessed anatomic variable correlates best with functional measurements of stenosis severity? A comparison of quantitative analysis of the coronary cineangiogram with measured coronary flow reserve and exercise/redistribution thallium-201 scintigraphy.


Input: Water content and equilibrium water partition in immature cartilage.


Input: Ischemic heart disease, age of more than 75 years, and the fact that the patient was a woman were independent predictors of poor cardiac function.


Input: Liquid chromatographic method for determination of citreoviridin in corn and rice.


Input: The incidence of cryptosporidiosis in young children was determined by staining of faecal specimens with a modified Kinyoun stain.


Input: The 4 degrees stimuli were found to elicit scalp distributions for the pattern reversal P100 and the pattern onset C1 consistent with striate and extrastriate visual cortical origins respectively.


Input: A Golgi study of the sixth layer of the cerebral cortex.


Input: Man and insect, past, present, future


Input: Mean fluorosis scores, however, were similar.


Input: Autonomic dysfunctions were restricted to tonic pupils.


Input: On the other hand, if the measured angle ANB is smaller than the calculated angle, the skeletal relation is Class III.


Input: These data should be useful in developing reagents for heterozygote detection and prenatal diagnosis of 11 beta-hydroxylase deficiency, the second most frequent cause of congenital adrenal hyperplasia.

11 beta-hydroxylase


Input: Neither ethanol nor estrogen has been shown to cause UROD-deficiency in animals.

UROD


Input: Although not common, the disorder is the most frequently diagnosed disturbance of porphyrin metabolism in many countries, and further insight into its unusual pathogenesis may clarify the hepatotoxic effects of the 4 etiologic agents.


Input: This means that the loss of recessives must be calculated by using a hypergeometric and not a binomial model as Fisher did.


Input: The poly (A) segment of the RNA was selectively cross-linked to the 72, 000-molecular-weight protein (72K protein).


Input: Possible pathogenetic mechanisms of hemopoietic changes in response to space flight effects are described.


Input: Development of a yeast system to assay mutational specificity.


Input: As a last resort, it may be possible to maintain a patient on dialysis in reasonable health with a DiaTAP button graft complex infected with Staphylococcus epidermidis and intermittent positive blood cultures using long term vancomycin therapy.


Input: Reward value of prosodic features of language for autistic, mentally retarded, and normal children.


Input: Due to its relatively soluble chemical form, 90Sr was rapidly translocated from lung to bone where a substantial portion was retained for a long period of time.


Input: Artificial ventilation was conducted using a tidal volume of 10 ml X kg-1 and a rate of 10 to 12 c X min-1.


Input: Significantly lower heart rate reactivity and significantly less pronounced left temporal artery pulse amplitude responses were found in non-medicated TH subjects than in controls.


Input: An epidemiological survey of rheumatic valve disease and rheumatic fever in primary and secondary school students in Jiangxi Province


Input: Heat-labile-like enterotoxin (LT) was produced by 26 of 42 stool isolates (62%), while only 1 of the 42 isolates (2%) produced enterotoxinlike activity in suckling mice; 65% of the cytotoxin-producing strains also produced an LT-like material.

LT

LT-like


Input: The nucleotide sequences of the human and murine ornithine decarboxylase mRNAs share an 85% homology, even in their 3'-noncoding regions.

human and murine ornithine decarboxylase mRNAs


Input: The absolute concentrations of alpha 2-plasmin inhibitor, alpha 2-macroglobulin, and antithrombin III increased with exercise (all P less than 0. 005), but when concentrations were corrected for acute shifts of plasma water during exercise, the quantity of these inhibitors actually decreased (all P less than 0. 005).

alpha 2-plasmin

alpha 2-macroglobulin

antithrombin III


Input: In the normal, basal (unstimulated) condition there were no significant correlations (p greater than 0. 05) between the systolic blood pressure and dopamine (r = 0. 09), norepinephrine (r = 0. 26), or epinephrine (r = 0. 27), nor were there significant correlations between melatonin and dopamine (r =-0. 01), norepinephrine (r =-0. 26), or growth hormone (r = 0. 17).

growth hormone


Input: In cases of 1 degrees HPT, the plasma 1, 25-(OH) 2D level rose significantly in all cases (P less than 0. 05), although the pattern of the increase was not uniform.


Input: It is largely predicted by lupus anticoagulant (estimated by activated partial thromboplastin time) and/or antibody to cardiolipin.

thromboplastin