Input: Data from 119 men and 40 women undergoing coronary angiography provide an opportunity to compare these associations in relation to a direct and continuous measure of atherosclerosis while controlling for age, sex, income, hypertension, serum cholesterol, smoking, angina, diabetes, family history of heart disease, Type A behavior pattern, and hostility.


Input: The presence in such patients of antibodies to adrenaline and noradrenaline is indicative of considerable disruption of catecholamine biotransformation.


Input: Effects of a low-energy laser beam on the cells of the newt embryo


Input: Samples from 1415 neurological patients were used to study the diagnostic value of acid alpha 1-glycoprotein in the lumbar cerebrospinal fluid.

acid alpha 1-glycoprotein


Input: Comparison of the amino acid sequence of the M RNA product of Uukuniemi virus with that of Punta Toro and Rift Valley fever viruses showed in both cases a weak homology that was more pronounced for the proteins located at the COOH-terminal end of the precursor.

M RNA product of Uukuniemi virus


Input: The purpose of this study is twofold: (1) to present a parallel form of the Gudjonsson Suggestibility Scale (GSS, Form 1); (2) to study test-retest reliabilities of interrogative suggestibility.


Input: The average deviations in the X-ray counts of the constant elements from the series means were used to correct the recorded count of the variable element in each block.


Input: To evaluate the relative accuracy of continuous wave (CW) and high pulse repetition frequency (HPRF) Doppler for estimating aortic transvalvular pressure gradients, Doppler examinations with both devices were obtained in 87 consecutive patients with aortic valve disease.


Input: The number of fecal pellets ingested peaked at 5 to 6 weeks old (13 pellets/day) and gradually decreased, thereafter (2. 1 pellets at 78 weeks old, 1. 5 pellets at 104 weeks old).


Input: Two of these six cases showed mucosal spread without stromal invasion (type A); the remaining four cases presented a direct extension (type B) from muscle-invasive carcinomas of the bladder.


Input: The development of a data base is described which can be used as common reference for ECG computer programs analyzing 12 or 15 simultaneously recorded leads.


Input: Contraction of the tracheal muscle and the activity of stretch receptors in the trachea


Input: The selenium level and glutathione peroxidase activity in the blood, liver, and stomach mucosa were significantly higher in the high-selenium diet group than in the low-selenium diet group.

glutathione peroxidase


Input: Amikacin was the most stable and tobramycin was the least stable aminoglycoside under the conditions tested.


Input: This may explain in part a secular trend towards reduced birthweight for gestation in preterm infants.


Input: Nickel is the most common cause of allergic contact dermatitis in Singapore, resulting in positive reactions in patch tests between 7 and 14%.


Input: Findings of positive potentials showed that N1 originated in the area of ventral gray matter through the ventro-lateral column and N2 through the dorsal column.


Input: Splenectomized patients are predisposed toward developing overwhelming bacterial infections.


Input: The rats were used for the study of the effects of sepsis on the utilization of exogenous fat emulsion.


Input: The possibility of a hereditary disorder leading to a minor defect in elastic fibre structure which could be responsible for the spontaneous lesions is discussed.


Input: N-Substituted trimethylsilylcarbamates were tested as derivatizing reagents for gas chromatographic analysis.


Input: The growing drug problem is also reflected in the increasing number of cases of hepatitis B and of drug-related deaths.


Input: Under the same hematocrit and flow conditions, the rate of oxygen saturation decrease was significantly higher for the sickle cells than for normal cells.


Input: The risk for these complications is increased by the following factors: multiple gestation, the combination of magnesium sulfate and beta-adrenergic agonist, and the use of adrenocortico-steroids to hasten fetal pulmonary maturity.


Input: Intensification of human myocardial contractile activity as affected by blood serum


Input: Inhibition of histalog-stimulated gastric secretion by 40 749 RP, a new long-acting gastric antisecretory agent.


Input: Five-year prospective study of peripheral white blood cells in infectious mononucleosis.


Input: Novel multigene families encoding highly repetitive peptide sequences.


Input: The M-3 subtype was an adverse prognostic factor.


Input: In addition, marked hypertension accompanied this disorder and all abnormalities, including the hypertension, responded to 1-desamino-8-D-arginine vasopressin therapy.

1-desamino-8-D-arginine vasopressin


Input: In 19 patients vagotomy not only curbed the bleeding but provided definitive therapy (Visick I-II); 4 patients died (mortality rate 16%).


Input: A yeast DNA fragment carrying the gene CP A1 encoding the small subunit of the arginine pathway carbamoyl-phosphate synthetase has been sequenced.

gene CP A1

carbamoyl-phosphate synthetase


Input: The H2 receptor antagonists and sucralfate cost about the same and have few side effects.

H2 receptor


Input: Such studied acquired with low energy or medium energy collimation and a window centered on the 159 keV 123I photopeak contain appreciable septal breakthrough signals originating from Compton scatter of high energy photons primarily from 124I.


Input: The concentrations of apo A-I and apo A-II of abstainers decreased significantly compared with the corresponding changes in controls.

apo A-I

apo A-II


Input: Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle.

Thyrotropin-releasing hormone


Input: Results of this study indicate that GLC of short chain fatty acids produced on agar medium by anaerobes, combined with simple tests such as Gram' s stain and colonial morphology, may allow fir direct presumptive genus identification from an initial pure agar culture.


Input: Tissue pressure, rCBF, and water content were measured from gray matter in the central core and the peripheral margin of the MCA territory over 6 h after MCAO.


Input: Dissolution of the Pt-30% Ir microelectrode tip was observed by scanning electron microscopy at charge densities as low as 200 microC/cm2 X ph (1 A/cm2), whereas erosion of activated iridium microelectrodes occurred only at the highest charge and current densities (3200 microC/cm2 X ph, 16 A/cm2).


Input: The results from the first five years of follow up in 1972 showed a 4. 7-fold excess mortality for ischaemic and other heart diseases (ICD A83-A84) compared with a comparable reference cohort of paper mill workers.


Input: The primary CT findings were misinterpreted as a brain infarct or possibly a tumour.


Input: However, kidneys perfused for 72 hr demonstrated more similar renal functions when tested by either IMPK or IBPK.


Input: It has been reported that rat blood chloroform levels were significantly decreased after treatment with ClO2.


Input: For this purpose, a simple respiration-control device has been developed that enables the patient to monitor breath-holding during successive scans.


Input: In the 10 patients with a more severe degree of steatorrhea the decrease in fat loss approached 20% and a close relationship was found (r = 0. 84, p less than 0. 01) between the extent of the fatty acid loss on placebo and the decrease of this loss on taurine.


Input: Polysorbate 80 did not have a direct stimulant or relaxant effect on either guinea pig ileum or rat uterus, however, it antagonised the contractions induced by acetylcholine, histamine, barium, 5-hydroxytryptamine and carbachol in a dose-dependent manner.


Input: Either a UV detector set at 268 nm or an electrochemical (EC) detector set at a potential of + 0. 9 V (versus Ag/AgCl/3 M NaCl) was used to monitor the drug.


Input: The mean transfer ratios of the drug into the genital tissues to the concentration in the uterine arterial blood were such that the transfer ratio into the portio vaginalis was the highest, followed by the uterine cervix and the myometrium, and that into the oviduct was the lowest with about 1/2 that into the portio vaginalis.


Input: Lower extremity weight bearing under various standing conditions in independently ambulatory patients with hemiparesis.


Input: These results were compared with those obtained in-D mothers and pups, after giving the mothers an oral supplement (10 i. u. vitamin D3/day) during the period of lactation (20 days).


Input: Treatment with oxyphenylbutazone and hydrocortisone failed to inhibit the raised serum CPN levels.

serum CPN


Input: 40, 000).


Input: Duration of remission in advanced gastric cancer patients responding to sequential dose of MTX and 5-FU


Input: The fast real-time digital processing of the N2 and flow signals incorporated filtering, delay compensation, and corrections for the effects of changes in gas composition and temperature.


Input: National Institutes of Health Consensus Development Conference Statement.


Input: Diagnosis: progressive multifocal leukoencephalopathy.


Input: The imino proton of T3 in the O6meG. T 12-mer and G3 in the O6meG. N 12-mer helix, which are associated with the modification site, resonate at unusually high field (8. 5 to 9. 0 ppm) compared to imino protons in Watson-Crick base pairs (12. 5 to 14. 5 ppm).


Input: Postnatal volumetric development of the prefrontal cortex in the rat.


Input: We also observed that the predictive ability of the selected attitudes and orientations increased considerably from 1975 to 1982.


Input: They also discuss the existing nomenclature.


Input: Estral cycle in white rats in the low and high mountains of Kirghizia


Input: Studies on the organic matrix of human ear ossicles


Input: Sensitization to hyperlactatemia induced by phenformin after subtotal ablation of the pancreas.


Input: Effect of variations in time interval between treatment with BCG and quartz dust on translocation of quartz dust from the lungs to their regional lymph nodes.


Input: Metastasis of colon carcinoma to the lip.


Input: Pre-beta-1 lipoprotein and early detection of risk factors for coronary heart disease.

Pre-beta-1 lipoprotein


Input: I.


Input: A study in vivo of adrenergic receptors in the rectum and in the internal and sphincter of the cat.

adrenergic receptors


Input: Problems common to pediatrics and anesthesiology


Input: Clinical course and nursing care of patients with decubitus ulcer--use of pillows stuffed with buckwheat chaff


Input: Re-examining methylbenzene (toluene) as a treatment for Ancylostomum caninum.


Input: Teratological studies on SF-837.


Input: 60th birthday of colonel prof. e. cerny m. d.


Input: Morphology of bacteriophages of Klebsiella bacilli.


Input: Benign intramural tumors of the esophagus


Input: Methyl mercury intoxication in rat kidneys.


Input: Disability insurance under social security.


Input: Analysis of clearance curve of rose bengal-I-131


Input: VII.


Input: Effect of a high-intensity SHF field on the blood coagulation system


Input: Plastic solution of elbow joint ankylosis with a decorticated cylindrical flap


Input: Effects of ionizing radiation in the human oral cavity and oropharynx: results of a survey.


Input: The Twentieth Anniversary of the Pomeranian Medical Academy.


Input: Study of antinuclear autoantibodies by immunofluorescence technic in collagen diseases

collagen


Input: Some reflexions apropos of a personal statistical study of 513 arterial embolisms


Input: Reactivities to horse anti-lymphocyte globulin.

horse anti-lymphocyte globulin


Input: The effect of osmotic flow on the distribution of horseradish peroxidase within the intercellular spaces of toad bladder epithelium.

horseradish peroxidase


Input: Nitrogen-hydrogen tautomerism in porphyrins and chlorins.


Input: A possible role for the mixed function oxidase enzyme system in the requirement for selenium in the rat.

oxidase


Input: Periodic breathing and apnea in preterm infants.


Input: Working session report: in vivo-in vitro screening.


Input: Dynamics of hospital stay in peptic ulcer patients


Input: A case of M hemoglobinosis


Input: Results of the official inspection of the commercial anti-inflammatory enzyme preparations containing chymotrypsin and trypsin by means of modified NF 13 methods

chymotrypsin

trypsin


Input: The content of glucosamine and galactosamine in tartar


Input: The non-role of fluoride in the control of plasma calcium in the parathyroidectomized rat.


Input: Modification of the growth of Tetrahymena by compounds which affect the adrenergic mechanism.


Input: Factors influencing in vitro skin permeability factor production by Vibrio cholerae.

skin permeability factor


Input: Midge control in flood channels.


Input: Tolerance test of HB 419 in animal experiments


Input: The distribution of body fluids following hemorrhage and resuscitation in combat casualties.


Input: Once more Hong Kong influenza in the Netherlands


Input: Early disagnosis of cancer--50 per cent of all patients could be cured


Input: Difficulties bound to measuring of sputum viscosity


Input: The absolute configuration at C-2 in monocrotalic acid.


Input: CO2 assimilation by chloroplasts illuminated on filter paper.


Input: The effect of low dosage radiation on metabolism and function of the rat kidney damaged by ischemia


Input: Quantitation of exocrine IgA in human serum in health and disease.

exocrine IgA


Input: Iodine metabolism in chronic thyroiditis.


Input: Propagation and hormone production by human normal and malignant trophoblast in rats.


Input: Morphogenesis of the trochanter produced by femoral regeneration in the phasmid Carausius morosus Br


Input: Nephrectomy applied to cattle


Input: Evaluation of automatic blood cell counters.


Input: The effect of a constant magnetic field on the phagocytic activity of Paramecia


Input: Relations between adrenergic mechanisms and analgesic effects


Input: The bearing of season and sequence of calving on frequency of male, female and total calvings in Hariana cows.


Input: Effect of castration on pituitary and serum LH and FSH in testosterone-sterilized rats.

pituitary and serum LH

FSH


Input: The significance of the phenolphthalein sulphatase test for the differentiation and identification of Nocardia species.

phenolphthalein sulphatase


Input: Effect of heparin on the inactivation of serum lipoprotein lipase by the liver in unanesthetized dogs.

serum lipoprotein lipase


Input: Experimental chlorpromazine cataracts.


Input: The need in the small hospital.


Input: Statistics of the past 5 years


Input: Naphthalene and paradichlorobenzene in clinical toxicology


Input: Story of a hospital that filmed its employee orientation program.


Input: Value of the method of passive hemagglutination with polysaccharide C in detecting C-reactive protein as compared to precipitation in capillaries and slide latex test with anti-CRP serum

C-reactive protein

anti-CRP


Input: Antimicrobial substance isolated from an acorn extract.


Input: On the amount and significance of the effective glucose level in tumors.


Input: The immuno-purified mRNA in the polysome complex was used to prepare cDNA with which to probe a D. melanogaster genomic library.


Input: Eight recombinant DNA clones of endogenous murine leukemia virus (MuLV)-related DNA sequences have been isolated from a lambdaphage genomic library of Balb/c mouse DNA.


Input: Mature mRNA for cytosolic phosphoenolpyruvate carboxykinase of the chicken is 2. 8 kilobases in length, similar to that previously noted for mRNA coding for the same enzyme in the rat.

cytosolic phosphoenolpyruvate carboxykinase of the chicken


Input: Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the " TATA box ".

CYC1 gene


Input: Plasma and erthrocyte lipid profile and lipoprotein lipase activity in postheparin plasma on vasectomized rabbits were studied and also the incidence of atherosclerosis in different arterial beds.

lipoprotein lipase


Input: Propranolol also effectively controlled her familial tremor.


Input: The distribution phase is followed by an elimination phase with a much longer half-life (mean value 375 min) and a volume of distribution of approximately 200-400 l.


Input: Plasma secretin, pancreozymin, and somatostatin-like hormone in chronic renal failure patients.

Plasma secretin

pancreozymin

somatostatin-like hormone


Input: We have followed 37 phenytoin-treated patients with reduced serum IgA concentrations for 2-7 years.

serum IgA


Input: Unusual course of plasmocytosis.


Input: Toxicity was significant in selected cases; three patients developed WBC counts less than 1, 000/mm3 and one of these patients died with sepsis.


Input: At Cabras (Oristano), a town characterized by a high incidence of thalassaemia and G6PD deficiency less than half the people between 18 and 35 have a fair knowledge of genetic diseases and of their prevention.


Input: Experience with the tensor fasciae latae free flap.


Input: The abluminal surface is often almost entirely encircled by a thick layer of fibrillary connective tissue.


Input: The customary coupling reagent sulfanilic acid has been replaced by 1, 3-dimethylbarbituric acid; CNCl is produced in the flow through system directly from KCN and chloramine T.


Input: Among six different library isolates containing 6. 5-to 7-kb IAP units, some restriction sites were highly conserved whereas others varied in both occurrence and position.

6. 5-to 7-kb IAP units


Input: During the period from May to August, 1978, an epidemic of hand, foot and mouth disease (HFMD) occurred in Gifu prefecture.


Input: We have investigated the requirements of the CH gene switch by characterizing two rearranged gamma 2b genes from a gamma 2b producing mouse myeloma (MPC-11).

CH gene

rearranged gamma 2b genes

gamma 2b


Input: WR-2721 (S-2-(3 aminopropylamino) ethylphosphorothioic acid) has been investigated for its ability to protect gut, lung, and testis, as well as fibrosarcoma (FSa) tumor nodules, in the lungs of mice from gamma-radiation injury.


Input: The ensembles are considered to be one of the forms of activity of the structured morphofunctional cortical units, i. e. the columns.


Input: The strong conservation of the inverted terminal repeat sequence may reflect a common integration mechanism for VL30 elements and MuLV proviruses.

VL30 elements


Input: In conclusion, these studies indicate that LiCl (1) decreases histamine-stimulated gastric acid secretion, and (2) diminishes bile-induced disruption of the gastric mucosal barrier in the canine Heidenhain pouch.


Input: Gel route preparation of low fusing dental porcelain frit.


Input: The dnaQ-lacZ and the rnh-lacZ fused genes were constructed and hybrid proteins with beta-galactosidase activity were produced.

dnaQ

lacZ

rnh

lacZ

beta-galactosidase


Input: The primary structure of the GAL7 5' flanking region has many features common to those of multicellular eukaryotic genes.

GAL7 5' flanking region


Input: Sweet oranges, mandarin, grapefruit, lemon, and lime are generally used for processing.


Input: Bepridil, a calcium antagonist with a half-life of approximately 42 hours, was compared with placebo in a double-blind, randomized, crossover trial.


Input: Climatic treatment of children with respiratory allergy


Input: The susceptibility of the PPNG strains to clinically relevant antibiotics varied with the plasmid pattern; this stresses the necessity of permanent surveillance of gonococcal infections and of regular evaluation of the recommendations for antimicrobial treatment.


Input: If facilities for measurements of O2 consumption and hence metabolic rate are available, these should be utilized.


Input: This generally means an energy intake of 1. 4 to 1. 6 times the energy expenditure, with a N intake of 250 to 400 mg/kg/day.


Input: The statistical analysis of data of TRH test on a sample of 57 healthy volunteers has permitted an evaluation of the upper limits of the normal thyrotropin response; the secretory area (As) was shown to be more discriminating.

TRH

thyrotropin


Input: Transitory subclinical and permanent hypothyroidism in the course of subacute thyroiditis (de Quervain).


Input: It is concluded that axillo-axillary by-pass is a simple solution for a complex haemodynamic, clinical and therapeutic problem.


Input: Endothelium of the central ear artery of an anesthetized rabbit is damaged by placing artery forceps on the ear directly over the vessel.


Input: Hydrocortisone seems to be unable to hinder the postdenervation changes in the muscle membrane whereas high doses of the hormone are able to induce changes in the muscle membrane.


Input: Significant clinical differences between the patients treated with and without AMB were longer survival time following diagnosis of illness (P less than 0. 05) and more frequent cranial nerve signs in the treated patients (P = 0. 089).


Input: Catch-up growth was observed only for a 12-month period in 4 children with a bone age of 7 to 8 years.


Input: The present paper elucidates the existing discrepancies, and offers a consistent terminology incorporating also such terms as " additivity ", " potentiation ", and " simple similarity ".


Input: Brainstem auditory evoked responses (BAERs) and quantitative saccadic eye movement studies provide information on the integrity of pathways traversing the brainstem.


Input: The salient clinical features, the problems of management and the modern approaches to the reconstruction of facial deformities seen in this disease are described.


Input: The rational for the prophylactic treatment, the therapy of the meningopathy and AIL-AIEOP protocols are exposed.


Input: Hepatitis B vaccine


Input: The Sarns 51F cavoatrial cannula decompressed the venous system as efficiently as the double caval cannulas.


Input: Three experiments contrasted the effects of 6-hydroxydopamine-induced lesions of the ventral noradrenergic and dorsal noradrenergic projections, predominantly to hypothalamus and cortex, respectively, upon body weight changes and food-related behaviour in the rat.


Input: Female Wistar rats were fed a liquid diet, Sustacal, which contained ethanol (40% of calories) or isocaloric sucrose.


Input: Introductory remarks.


Input: Combination of a Shwachman syndrome and a complex granulocyte function disorder in a girl


Input: Trial 3 broiler chickens were maintained on control feed until they reached 3 weeks of age at which time they were taken off of feed for 2. 5 hr and then placed on either control feed or feed containing 4. 0 ppm ochratoxin A, and heart rate and blood pressure were measured every half hour through 7 hr.


Input: While these findings may reflect the sensitivity of a thick myocardial wall to ischaemia during surgery, the postoperative recovery was not related to the serum CK-MB level.

serum CK-MB


Input: Using a MOS-Hypersil reversed-phase column with a phosphate buffer--acetonitrile mobile phase, baseline separation of antipyrine, its metabolites 3-hydroxymethylantipyrine, norantipyrine and 4-hydroxyantipyrine, and the internal standard, phenacetin, was achieved within 6 min.


Input: Serum lipids and lipoproteins of 29 insulin dependent diabetic children have been determined and related to the metabolic status of the patients.

insulin


Input: The AD components were markedly more dependent on the affective state of the rat then was the V1 component.


Input: HBB concentration in the fetuses indicated little, if any accumulation.


Input: All samples exhibited a decline in ethanol concentration, with most losses falling within the expected 20 to 40 mg% range.


Input: Pilot study of blood coagulation in gout patients.


Input: Further, the reduction in 5-hydroxytryptophan (5-HTP) accumulation by LSD showed regional differences in inhibition by methiothepin (hypothalamus greater than cortex greater than striatum) which paralleled the autoreceptor antagonist activity of methiothepin in vitro. (ABSTRACT TRUNCATED AT 250 WORDS)


Input: Effects of methiothepin and lysergic acid diethylamide on serotonin release in vitro and serotonin synthesis in vivo: possible relation to serotonin autoreceptor function.

serotonin autoreceptor


Input: In a recent measles epidemic in El Paso, TX, 120, 000 records were screened using these criteria, and as a result 13, 000 students were vaccinated.


Input: Twenty-one percent of these patients had neurologic disease that appeared to be responsible for the tinnitus.


Input: Bullous angiolymphoid hyperplasia with eosinophilia


Input: The hypertension with elevated PRA, however, was resistant to the angiotensin II (AII) analog [Sar1, Ile8] ALL.

angiotensin II

AII


Input: Volume of distribution of total DMDZ (range, 1. 33 to 6. 30 l/kg) and of unbound DMDZ after correction for protein binding (range, 43 to 243 l/kg) was larger in women than in men of all ages, and in the elderly as opposed to the young.


Input: Effects of dopamine and of a dopaminergic blocker, haloperidol, on the responses of carotid body chemoreceptors to hypoxia and hypercapnia were investigated in 16 anesthetized cats.


Input: The alterations in differentiation of osteoprogenitor cells, together with the failure of mineralization, resulted in significantly lower rates of bone formation (as measured by fluorochrome labeling) in the magnesium-deficient rats.


Input: The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes.

immunoglobulin delta genes


Input: There is now a significative difference between age group 1-5 and the others (p Less Than 0, 02).


Input: Factor VIII procoagulant activity, antigen concentration and von Willebrand activity as ristocetin cofactor were determined several times in 10 patients with DIC.

Factor VIII

von Willebrand

ristocetin cofactor


Input: In silicosis, significant relationships between patients and sons were not seen with respect to arterial blood gas determinations and ventilatory responses except for Paco2 of patients and hypercapnic ventilatory responses of sons.


Input: For steers the urinary N values were 403 and 295 mg/kg W0. 75 at 200 and 350 kg live weight respectively and total N excretion including faecal N was 408 and 320 mg/kg W0. 75.


Input: TEMTU and DPTU were the most potent teratogens.


Input: Similar observations were made with unilateral pneumothorax of 15 cmH2O for 30 min.


Input: Fibromuscular intimal thickening was seen in the ascending and thoracic aorta of the swine fed 62, 500 IU of vitamin D3/kg of diet for three months duration; and after 3 months of vitamin D3 withdrawal, atherosclerotic lesions were found.


Input: Detection of exercise-induced asynergy by M-mode echocardiography.


Input: Both groups were subjected to tests of delayed hypersensitivity with Candidin, Trycophytin and Tuberculin.

Candidin

Trycophytin

Tuberculin


Input: Efficacy of cervical spine immobilization methods.


Input: Circulating platelets may be activated by exposed triple-helical collagen in atherosclerotic lesions in Mg-deficient ruminants.

collagen


Input: In the ultramarathon runner the testosterone levels sharply rose at the beginning of the training session (from the 7, 20 ng/ml to 11, 50 ng/ml after 20' training), and subsequently decrease after 3 hours (9, 20 ng/ml) and at the end of the 6 hours training (4, 60 ng/ml).


Input: Terbutaline; a beta2-adrenergic agonist, and aminophyllin, a phosphodiesterase inhibitor, were given separately, or in combination, to rabbit fetuses on the 28th day of gestation.


Input: The hyperacute phase of posterolateral myocardial infarction.


Input: After a year of planning in the Laboratory Assistants' School in Stockholm: new education for laboratory assistants is now arranged


Input: The electrocardiogram.


Input: The Authors have proposed to develop this research employing a preparation containing exclusively a cortisonic, the desametazone, in order to evaluate the alterations of the dentinogenesis to be attributed to such component.


Input: Secretory IgA and serum immunoglobulins as indices of the local immunity of the intestinal mucosa in acute leukemias

Secretory IgA

serum immunoglobulins


Input: Fluorometric methods can also provide information about porphyrin binding sites that is useful in understanding porphyrin transport and clearance.


Input: The monoexponential rate of clearance of tracer--obtained from the portion of the residue-detection curve reflecting metabolism of fatty acid incorporated into neutral lipids--correlated directly with induced changes in tension-time index after injections into the left atrium (r = 0. 96, n = 12), right atrium (r = 0. 86, n = 14), and ear vein (r = 0. 93, n = 14).


Input: Specific IgE levels decreased slightly, but always remained within the pathological range.

IgE


Input: Correlation between intraocular involvement and systemic outcome was poor.


Input: The results indicate that folate compounds decrease formate accumulation after methanol by stimulating formate oxidation or utilization and suggest a possible use for folates in the treatment of certain cases of human methanol poisoning.


Input: The " cracked-tooth " syndrome.


Input: The foregoing results show that CXD has high efficacy and safety and it can be said that it is a drug required in the pediatric field.


Input: Based on peptide map similarities, partial amino-terminal sequence data, and common genetic origin, it is suggested that p60 and p62 have identical amino acid sequences carboxy-terminal to the p60 initiator methionine (residue 21 of p62).


Input: Diagnosis of phenylalanine hydroxylase deficiency (phenylketonuria).

phenylalanine hydroxylase


Input: The uncomplicated cases of typhoid fever were found to have an intact CMIR as compared to the complicated cases.


Input: There was a significant correlation between tubular diameter and spg (r = 0. 68, P less than 0. 001) suggesting that tubular diameter measurements in histological sections could be used to predict sperm production.


Input: The differential investigation of lipoproteins, however, showed that the high-density lipoprotein (HDL) fractions are absolutely or relatively decreased with respect to low-density lipoproteins (LDL) in cerebral infarcts and in transient ischaemic attacks.

high-density lipoprotein

HDL

low-density lipoproteins

LDL


Input: A note on some consequences of UV vision in birds.


Input: Parasitological and pathological findings in capuchin monkeys infected with Schistosoma japonicum or Schistosoma mansoni.


Input: In the past, immunology in Singapore was mainly confined to serology for the diagnosis of certain infectious diseases.


Input: Modification of enteral resorption by cytostatic therapy


Input: In vitro penetration tests of human sperm into cervical mucus were introduced in order to study the interaction between sperm and cervical mucus.


Input: Vibrio fluvialis (group F vibrio) in Maharashtra.


Input: The hormonal response to a standardized bicycle exercise test was studied in 11 male cadets exposed to a course of 107 h of continuous activity with less than 2 h sleep.


Input: At an ambient temperature of 25 degrees C, the responses to spinal cooling are reduced during the dark phase.


Input: Ulcer appeared on the angulus of the stomach at the 28th week and resulted in ulcer scar at the 42nd week.


Input: Results of the recognition task revealed significant effects of consonant voicing, position and vowel context on syllable recognition.


Input: Visual response properties of neurons in four extrastriate visual areas of the owl monkey (Aotus trivirgatus): a quantitative comparison of medial, dorsomedial, dorsolateral, and middle temporal areas.


Input: A unified approach to the standardization of allergens.


Input: A dose-dependent fall in GABA content was observed; GABA decrease was evident 15 min after the administration, reached its nadir at 60 min and disappeared at 120 minutes.


Input: For monocytes, as measured on the Hematrak, it was 13. 4%.


Input: Evoked potential and single unit responses to olfactory nerve volleys in the isolated turtle olfactory bulb.


Input: While all deletions within the sequence coding for the mature tRNA led to inactivity of the mutated genes, substitution of the central portion by concatenated Hind III linkers produced gene units active in transcription.

concatenated Hind III linkers


Input: Survival was calculated both from the date of onset and from the date of diagnosis.


Input: With Sair and So2, mean vital capacity was reduced by 44% from control.


Input: Of the 117 patients (out of the 136) with serologic evidence of chronic thyroiditis who could be studied, eight (7%) had hyperthyroidism and 45 (38%) were hypothyroid.


Input: The new semi-synthetic oral cephalosporin, CGP 9, 000, has been evaluated in a large number of hospitalized patients with urinary infections.


Input: Current status of chemotherapy for Hodgkin' s disease


Input: Over a period of 15 days 16% of the dose administered was excreted with faeces and 0. 9% in the urine.


Input: Electron microscopic picture of the cerebral cortex in rats cooled to 22 degrees C


Input: Thirty-one age-matched, conscious, virgin, male Sprague-Dawley rats and spontaneously hypertensive rats (SHRs) were individually injected with a single subcutaneous dose of 85 mg/kg dl-isoproterenol to determine the degree and time course of drug-induced cardiac failure and functional recovery.


Input: Prevention of transfusion reactions by the use of saline washed red blood cells.


Input: The geometric mean hemagglutination-inhibition antibody titers (GMT) of non-immunized, once-immunized, and twice-immunized chickens were compared at 2-week intervals following primary immunization, secondary immunization, and challenge.


Input: 100 more than in the summer coat).


Input: Two new artifacts in automated coagulation testing.


Input: This relatively simple and easily performed technique of measuring deep muscle temperature appears to be a useful adjunct in choosing the amputation level.


Input: Changes in immunologic reactivity in subjects receiving transfer factor could not be distinguished from those in subjects receiving placebo.

transfer factor


Input: Charcoal-facilitated dialysis.


Input: Retinal changes in pigmentary retinopathy in children


Input: As a result, beta-apo-8'-carotenoic acid ethyl ester (apo-EE) was used as a reference standard in Experiments 4 to 6.


Input: Six hours after the last administration, uterus of Gf and Cv mice were weight 337. 6 mg% and 423. 5 mg% respectively, the difference was statistically significant (p less than 0. 01).


Input: Analysis of an autopsy population.


Input: Autoradiographic localisation of its cellular distribution in the kidney.


Input: Microscopic anatomy and cell population dynamics.


Input: In 11 patients with Horton' s headache morphological investigations (differential white blood cell count), cytoenzymatic determinations (alkaline and acid phosphatase, non-specific esterase) and cytoimmunological tests (IgM and IgG binding) were carried out on capillary blood neutrophils obtained from the area of pain, non-painful area of the skin on the head on the contralateral side, and from the finger.

alkaline and acid phosphatase

non-specific esterase

IgM

IgG


Input: The resulting R protein terminates five codons downstream of the frameshift site at the V protein stop codon.

R protein

V protein


Input: BSE and farmworkers.


Input: Peroxisome proliferator-activated receptors (PPARs) and retinoid X receptors (RXRs) are nuclear hormone receptors that are activated by fatty acids and 9-cis-retinoic acid, respectively.

Peroxisome proliferator-activated receptors

PPARs

retinoid X receptors

RXRs

nuclear hormone receptors


Input: The number of lactotropes, somatotropes, thyrotropes, and gonadotropes was not altered compared with controls, indicating that in the adult pituitary, POMC products are not required to maintain the distribution of cell types.

POMC products


Input: In electrophoretic mobility shift assays, the PERE formed three major complexes (P1, P2 and P3) with proteins in nuclear extracts from HeLa or 293 cells.

PERE


Input: That sequence strongly promoted the transcription of the promotorless chloramphenicol acetyltranferase (CAT) gene in cells of pancreatic origin (AR-42J) but not in cells of non-pancreatic origin (Rat 2 and IEC 6).

chloramphenicol acetyltranferase

CAT


Input: In the absence of E1A243, YY1 represses CRE-dependent transcription of c-fos by physically interacting with ATF/CREB proteins bound to the-67 CRE.

c-fos

ATF

CREB


Input: TPBF has two potential coiled-coil regions, a basic region, a proline-rich region, a histidine-rich N terminus, and a nuclear targeting sequence.

TPBF


Input: To confirm the GapIII protein activity, constructs containing different GapIII-GRD domains were transformed into iral mutant yeast to determine their relative ability to replace IRA1 functionally.

GapIII protein

GapIII

GRD

iral


Input: A water-vapour giga-maser in the active galaxy TXFS2226-184.


Input: These incisors were studied by scanning electron microscopy-energy dispersive spectroscopy analysis (SEM-EDS) and light microscopy to examine the calciotraumatic lines of strontium in the rat incisor labial dentin.


Input: Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA.


Input: Hepatitis B surface antigen was detected in 2 patients, with negative hepatitis C virus antibody.

Hepatitis B surface antigen

hepatitis C virus antibody


Input: Liver transplantation in one patient resolved metabolic complications but did not improve PMN count or the infectious status, while neutropenia was corrected by G-CSF.

G-CSF


Input: Joys and F.


Input: Tyrosine phosphorylation of cellular proteins is the earliest identifiable event following T-cell antigen receptor (TCR) stimulation and is essential for activating downstream signaling machinery.

T-cell antigen receptor

TCR


Input: The interferon-induced RNA-dependent protein kinase (PKR) is considered to play an important role in the cellular defense against viral infection and, in addition, has been suggested to be a tumor suppressor gene because of its growth-suppressive properties.

interferon

RNA-dependent protein kinase

PKR


Input: Moreover, Lck was reversibly co-immunoprecipitated with p95Vav, and the stoichiometry of binding increased in anti-CD3-treated Jurkat cells.

Lck


Input: Interleukin-8 (IL-8) is a potent inflammatory mediator that belongs to the family of C-X-C chemokines.

C-X-C chemokines


Input: Three mutants (pms1, pms2 and pms3) isolated earlier from MW104-1B were shown to correct in vitro constructed plasmids with defined DNA mismatches (G/T, A/C, G/G, etc.) poorly (Kramer et al., 1989a).


Input: Hematopoietic growth factors are being used to accelerate the recovery of myelopoiesis following high-dose chemotherapy in cancer patients.

Hematopoietic growth factors


Input: A particularly striking HpaII tiny fragment island, extending over nearly 2, 000 base pairs, surrounds the USF2 translation initiation site.

HpaII

USF2 translation initiation site


Input: Dilutions of H-2b or H-2d NP peptides indicated that 3-4 logs less H-2b NP peptide was required to sensitize syngeneic target cells for CTL-specific lysis, suggesting that the differing affinities of H-2b and H-2d major histocompatibility complex molecules for their peptides likely account for the total removal of NP CTL in the H-2b mice but only partial removal in H-2d mice made to express thymic NP.

H-2b or H-2d NP peptides

H-2b NP peptide

major histocompatibility complex molecules


Input: Although both transfected cell lines contain FGF-1 cell surface receptors as judged by crosslinking studies, the wild-type transfectants are refractory to exogenous FGF-1, whereas the mutant transfectants respond normally. (ABSTRACT TRUNCATED AT 250 WORDS)

FGF-1 cell surface receptors


Input: The median post-treatment, pre-operative serum PSA was 0. 4 ng/ml.

serum PSA


Input: The amino acid sequences of the predicted RfbA and RfbB homologs showed identities of 75. 7% (87. 9% total similarity) and 78. 0% (86. 5% total similarity), respectively.

RfbA

RfbB homologs


Input: In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells engineered to express the murine Mpl receptor (BaF3/mMpl).

murine Mpl receptor

mMpl


Input: A chicken paxillin cDNA was also cloned and is predicted to encode a protein approximately 90% identical to human paxil-lin.

chicken paxillin cDNA

human paxil-lin


Input: In vivo association between Shb-SH3 domain proteins v-Src and Eps8 was detected by coimmunoprecipitation.

Shb

v-Src


Input: As expected, the insulin effect to increase ras GTP formation and MAP kinase activity was negligible in A/K1018 cells but normal, or supernormal, in Y/F2 cells.

insulin

ras GTP

MAP kinase


Input: Appropriate restriction sites allow one to insert virtually any desired cDNA fragment directly behind the epitope-specific sequence and before a long poly (A) tail.


Input: The gene product of cotS was confirmed to be identical to Cot40-2 by SDS-PAGE and immunoblotting from Escherichia coli transformed with a plasmid containing the cotS region.

cotS

cotS region


Input: The optimal care of CHF patient includes the recognition and management of these electrolyte disturbances.


Input: METHODS: rHb1. 1 or human serum albumin was administered intravenously to fasting male volunteers.

rHb1. 1

human serum albumin


Input: A mutant (residues 1-332) showed complete Ca2 +/CaM-dependent activity.

CaM


Input: The two bases immediately flanking the 5' end of the element proved to be very important to its function as a UAS element as did the two bases immediately 3' of the bHLH core motif.


Input: These results indicate that the PCNA gene is a likely target gene of E2F.

PCNA gene


Input: Differential sensitivity of the MMPI-2 depression scales and subscales.


Input: The chloramphenicol-resistance transposon Tn4451 undergoes precise conjugative deletion from its parent plasmid plP401 in Clostridium perfringens and precise spontaneous excision from multicopy plasmids in Escherichia coli.

chloramphenicol-resistance transposon Tn4451


Input: A general model for ARE-mediated mRNA degradation involving a potential role for certain heterogeneous nuclear ribonucleoproteins and ARE-binding proteins is proposed.

ARE-binding proteins


Input: Individual mutations in motifs III, IV, and V had distinctive effects on the affinity of enzyme for GTP, the rate of covalent catalysis (EpG formation), or the transfer of GMP from enzyme to RNA.


Input: Mutational analysis of mRNA capping enzyme identifies amino acids involved in GTP binding, enzyme-guanylate formation, and GMP transfer to RNA.

mRNA capping enzyme


Input: Staphylococcal enterotoxin A involvement in the illness of a 20-month-old burn patient.

Staphylococcal enterotoxin A


Input: These results suggest that G beta gamma-stimulated Shc phosphorylation represents an early step in the pathway leading to p21ras activation, similar to the mechanism utilized by growth factor tyrosine kinase receptors.

G beta gamma

Shc

growth factor tyrosine kinase receptors


Input: Negative-staining, refractile mycobacteria in Romanowsky-stained smears.


Input: Here we focused on the role of the 5' proximal regulatory cassette (-190; + 53 bp) of the rat enkephalin (rENK) gene in the developmental regulation of the enkephalin phenotype.

rat enkephalin

rENK

enkephalin


Input: Unexpectedly, all ENK-specific motifs formed specific and highly abundant protein-DNA complexes when nuclear extracts from the human tumor cell line (HeLa), which does not express ENK, were used.

ENK-specific motifs

ENK


Input: Infant aged 3. 5 years presents persistence of primordial vitreous body with crystalline dislocation in the camera aquosa and secondary buphthalmos of the left eye and microphthalmos with dislocation of the crystalline in the vitreous body of the right eye.


Input: Imaging features of splenic epidermoid cyst with pathologic correlation.


Input: SL1 trans-splicing specified by AU-rich synthetic RNA inserted at the 5' end of Caenorhabditis elegans pre-mRNA.


Input: Overexpression of wild-type p53 also induces apoptosis in an LCL.

wild-type p53


Input: These observations lead to the proposal that the RNAP II CTD might be an in vivo target for the activated p42mapk and p44mapk MAP kinases.

RNAP II CTD

p44mapk MAP kinases


Input: We also isolated two alternatively spliced forms of human CD6 cDNA lacking sequences encoding membrane-proximal regions of the cytoplasmic domain which maintain the same reading frame as CD6-PB1.

human CD6 cDNA


Input: We have isolated a Drosophila melanogaster (Dm) cDNA encoding a polypeptide that has extensive sequence similarity to the mammalian MAPKAPK-2.

mammalian MAPKAPK-2


Input: A 2. 4-kb MAPKAPK-2 message is expressed throughout development, while two shorter transcripts of 2. 3 and 1. 8 kb appear to be specifically expressed in the germline.

2. 4-kb MAPKAPK-2 message


Input: The integrity of the cDNA sequence was confirmed by analysis of several overlapping genomic clones that span the GAR1 gene.

GAR1 gene


Input: Phorbol esters stimulated phosphorylation of CSK 35H proteins, thus emphasizing that sequences isolated according to PKC binding activity in vitro are also PKC substrates in vivo.

CSK 35H proteins

PKC

PKC


Input: One of these is surrounded by an adenine-uridine rich region that can form an 11-base pair stem structure.


Input: Additionally, the enzyme shows activity towards triglycerides such as olive oil and tributyrin and towards egg-yolk emulsions.


Input: The nucleotide sequence directly upstream of fimA contains two open reading frames, ORF5 and ORF1, whose deduced protein products are homologous to members of a superfamily of ATP-binding cassette membrane transport proteins, including both prokaryotic and eukaryotic uptake and export systems.

fimA

ATP-binding cassette membrane transport proteins


Input: The ORF3 probe also hybridized to a 540 bp transcript consistent with the size of ORF3 alone and supportive of the mutagenesis data of non-linkage.


Input: Mean growth changes in this Class II sample were comparable to those previously reported for male subjects with Class I malocclusions over the same age period, suggesting a similarity in postpubertal development between these two groups.


Input: By in vitro immunoprecipitations and gel shift assays, we identified two classes of high affinity Engrailed-binding sites upstream of each of the two polyhomeotic transcription units.

Engrailed-binding sites


Input: Subjects with a short postexposure time and a dioxin burden > 0. 6 pg/m3 had a significantly higher risk of hypoergy than unexposed subjects (hypoergy I: OR = 9. 51, 95% CI = 1. 96-42. 02; hypoergy II: OR = 2. 92, 95% CI = 1. 14-7. 5).


Input: Analysis of this sequence combined with that previously reported for the 5'-flanking region directly proximal to the start of transcription revealed several putative regulatory sequences.


Input: The experimental design represents a 2 x 3 factorial arrangement of treatments with three dietary levels of incorporation of RSB (0, 50, and 100%), and chickens either infected or uninfected.


Input: A cDNA clone corresponding to the putative GA 20-oxidase genomic sequence was constructed with the reverse transcription-PCR method, and the identity of the cDNA clone was confirmed by analyzing the capability of the fusion protein expressed in Escherichia coli to convert GA53 to GA44 and GA19 to GA20.

GA 20

oxidase


Input: Total cholesterol was also reduced at week 12 by 17. 0% (20 mg/day) and 15. 7% (20-30 mg/day), and at week 52 by 20. 4% (< or = 20 mg/day) and 19. 2% (> or = 30 mg/day).


Input: Piperacillin-tazobactam can be used for the treatment of infections caused by gram-negative, gram-positive, aerobic, and anaerobic bacteria.


Input: This apparently anomalous structure/activity relationship raises important issues for understanding the evolution of regulatory peptides and the mechanisms that control their expression.


Input: This paper summarises the experimental evidence upon which the clinical trials of aldose reductase inhibitors in diabetic patients have been initiated and the results of published drug trials in these patients.

aldose reductase


Input: Increase in urinary calcium and oxalate after fructose infusion.


Input: The Babcock Surgical Clinic.


Input: Histopathological features of relapsed leprosy.


Input: One of these factors, HRF-1, recognizes a cis element consisting of an inverted palindromic motif.


Input: Regulation of Gax homeobox gene transcription by a combination of positive factors including myocyte-specific enhancer factor 2.

Gax homeobox gene

myocyte-specific enhancer factor 2


Input: The carboxyl-terminal transactivation domain of heat shock factor 1 is negatively regulated and stress responsive.

heat shock factor 1


Input: The RAT3 gene encodes an 1157-amino acid protein without similarity to other known proteins.

RAT3 gene


Input: CCAAT/enhancer-binding protein isoforms beta and delta are expressed in mammary epithelial cells and bind to multiple sites in the beta-casein gene promoter.

CCAAT/enhancer-binding protein isoforms beta and delta

beta-casein gene promoter


Input: We have found that the expression of GTPase-deficient mutants of alpha 12 (alpha 12Q229L) or alpha 13 (alpha 13Q226L) leads to robust activation of the Jun kinase/stress-activated protein kinase (JNK/SAPK) pathway.

GTPase

alpha 12

alpha 12Q229L

alpha 13

alpha 13Q226L

Jun kinase

stress-activated protein kinase

JNK

SAPK


Input: Using mutagenesis, we have identified two mutations of the second actin-binding domain that can also suppress the act1 mutations of interest.

actin-binding domain


Input: The normal cell cycle is regulated by several molecules, such as the tumor-suppressor protein pRb, the G1 cyclins, the cyclin-dependent kinases, and their inhibitors.

tumor-suppressor protein pRb

G1 cyclins

cyclin-dependent kinases


Input: These results are very useful for deciding on the doses of hormones and the expected serum estradiol level in HRT for Japanese women.


Input: Comparison of 1. 5 Tesla and 0. 35 Tesla field strength magnetic resonance imaging scans in the morphometric evaluation of the lumbar intervertebral foramina.


Input: A new vector, pHBK280, was designed to facilitate this analysis.


Input: Here we describe an in vitro assay where the NS3-4A polyprotein, NS3, the serine proteinase domain (the N-terminal 181 residues of NS3), and the NS4A cofactor were produced by cell-free translation and tested for trans-processing of radiolabeled substrates.

NS3-4A polyprotein

serine proteinase domain (the N-terminal 181 residues of NS3)

NS4A cofactor


Input: In contrast, over-expression of RAR beta only poorly restored differentiation, although it could replace RAR gamma for the activation of target genes.

RAR beta

RAR gamma


Input: The 5'-terminus of the p-gvpF-M mRNA was located 169 nucleotides upstream of p-gvpF within p-gvpE.

p-gvpF-M mRNA

p-gvpF

p-gvpE


Input: However, the relative binding affinity for the motifs is different.


Input: The transport of a genetically engineered chimeric transmembrane protein connected to this ER leader sequence was as efficient as that of the original protein from which the ER sequence has been derived.


Input: A polymorphic bipartite motif signals nuclear targeting of early auxin-inducible proteins related to PS-IAA4 from pea (Pisum sativum).

PS-IAA4 from pea (Pisum sativum)


Input: The plant hormone auxin transcriptionally activates early genes.

early genes


Input: A new non-LTR retrotransposon provides evidence for multiple distinct site-specific elements in Crithidia fasciculata miniexon arrays.


Input: The CVA16. 4 proteolipid transcript is the most prevalent of the two proteolipid messages in expanding ovules harvested 10 d post-anthesis.

CVA16. 4 proteolipid transcript


Input: The synthetic DNA sequence was constructed to achieve efficient base pairing with Escherichia coli 16S ribosomal RNA, avoidance of internal secondary structure, and optimal codon usage for high-level protein expression in accord with the known preferences in E. coli.

Escherichia coli 16S ribosomal RNA


Input: Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate the expression of tissue-specific genes in a number of mammalian and insect systems.


Input: EsaR can repress its own expression but seems not to regulate the expression of esaI.

EsaR

esaI


Input: We conclude that, in comparison to reports from other regions, Scandinavian renal transplant recipients are at high risk of dying of IHD.


Input: Veterinary certification for livestock export.


Input: Diffuse white matter injury can be attributed to radiation and associated with neurological deficits, but leukoencephalopathy is rarely observed in the absence of chemotherapy.


Input: The ectopic expression of Oct-3/4 in hybrid cells under a constitutive promoter is sufficient for transcriptional activation of an octamer-dependent promoter.


Input: We here demonstrate that a temperature-sensitive fission yeast mutant which has a mutation in a homologous gene, and two of three additional (mtr1/prp20/srm1) mutants accumulate nuclear poly (A) + RNA at 37 degrees C.


Input: Since RCC1p acts as GNRP for Ran, a small nuclear GTPase of the ras superfamily, we have identified two homologs of Ran in S. cerevisiae (CNR1 and CNR2).

GNRP

Ran

small nuclear GTPase

ras superfamily

Ran


Input: Prostate specific antigen shows the metastatic cases better [correction of worse] than prostatic acid phosphatase.

Prostate specific antigen

prostatic acid phosphatase


Input: Of these carriers 149 were diagnosed to be asymptomatic clinically, biochemically and echographically.


Input: Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.

proto-oncogene c-kit

c-kit product


Input: Insulin-like growth factor-binding protein-2 (IGF-BP-2) transcription in rat liver varies with developmental age and fasting.

Insulin-like growth factor-binding protein-2


Input: The presence of the RV 5' (+) SL sequence had the primary enhancing effect on translation.


Input: By contrast, all proteins initiated with a methionine placed one residue upstream of the natural N terminus of PR failed to show specific proteolysis.

PR


Input: Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.

Reverse transcriptase

Gag

Pol


Input: PATIENTS AND METHODS: We report our experience with seven children with active small bowel Crohn' s disease given a casein-based, polymeric feed rich in TGF-beta 2 (Specific Polymeric Diet; Nestle-Clintec; Vevey, Switzerland) as complete nutrition for 8 weeks.

casein

TGF-beta 2


Input: The leader sequence of the isolated cDNA clone contains several small open reading frames upstream of the initiation codon of the largest open reading frame coding for the homeodomain protein.

homeodomain protein


Input: Experimental adhesion prophylaxis with recombinant tissue plasminogen activator.

recombinant tissue plasminogen activator


Input: To determine which sequences in the rat P450c17 promoter may be responsible for basal and cAMP-stimulated gene transcription, deletion constructs containing between-1, 560 and-53 base pairs of 5'-flanking DNA from the rat P450c17 gene were ligated to plasmids expressing the reporter gene luciferase and transfected into two mouse cell lines, adrenal Y-1 cells, and testicular Leydig MA-10 cells.

rat P450c17 promoter

rat P450c17 gene

luciferase


Input: We have cloned and sequenced the mouse NMO1 cDNA, which encodes the NAD (P) H: menadione oxidoreductase [also called NAD (P) H: (quinone acceptor) oxidoreductase; quinone reductase; azo dye reductase; DT diaphorase; EC 1. 6. 99. 2].

mouse NMO1 cDNA

NAD (P) H: menadione oxidoreductase

NAD (P) H: (quinone acceptor) oxidoreductase

quinone reductase

azo dye reductase

DT diaphorase

EC 1. 6. 99. 2


Input: Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles.

VPS45 gene


Input: In 293 cells, expression of the NF-kappa B inhibitor, I kappa B-alpha, reduced the stimulatory activity of LMP.

NF-kappa B

I kappa B-alpha

LMP


Input: Binding of meAda is necessary to activate transcription of the adaptive response genes; accordingly, in vitro transcription of aidB is dependent on the presence of meAda.

meAda

aidB

meAda


Input: No significant differences were identified between groups for pH, PaCO2, intracranial pressure, heart rate, brain temperature, or glucose levels.


Input: Weak allergenicity of recombinant hirudin CGP 39393 (REVASC) in immunocompetent volunteers.

recombinant hirudin CGP 39393


Input: Each dietary treatment was fed to six pen replicates of five chicks per pen for 21 d.


Input: The NarX and NarQ proteins with amino acid substitutions at the first conserved histidine position were also unable to dephosphorylate NarL-phosphate in vitro.

NarX

NarQ proteins

NarL


Input: The Ng/RC3 and PKC-gamma genes have a similar expression pattern in the brain during development.

PKC-gamma genes


Input: Structure and regulation of the gene encoding the neuron-specific protein kinase C substrate neurogranin (RC3 protein).

protein kinase C

neurogranin

RC3 protein


Input: As in Tb, U6 is a single-copy gene and two tRNA genes, tRNAGln and tRNAIle, are found upstream to the gene.

tRNAGln

tRNAIle


Input: Two mammalian enzymes, the haem-controlled repressor (HCR) and the double-stranded RNA-activated inhibitor (dsI), phosphorylate Ser-51 of the alpha subunit, thereby inhibiting the exchange of bound nucleotides on, and thus the recycling of, eIF-2.

haem-controlled repressor

HCR

double-stranded RNA-activated inhibitor

dsI


Input: A triple Ser--> Ala mutant form of yeast eIF-2 alpha was found to be no longer phosphorylated by either of the yeast (or mammalian) casein kinase activities in vitro.

eIF-2 alpha

casein kinase


Input: Binding activity in rat liver nuclear extracts includes these orphan receptors as judged from electromobility supershift experiments and from results obtained with expressed receptors, although the element in CYP2C11 did not bind HNF-4.


Input: Transcript analysis reveals that lethal B block substitutions reduce U6 RNA synthesis at least 10-fold in vivo and 20-fold in vitro.

B block

U6 RNA


Input: Lung function tests (EFR) were performed on these patients for a period of 19. 2 +/-3. 4 months.


Input: Staphylococcus aureus and CNS showed high or moderate resistance rates to methicillin (DMPPC).


Input: Hybridization signals were also detected with total DNAs of Rhizobium leguminosarum bv. phaseoli, Rhodobacter capsulatus and Escherichia coli, but not those of Xanthomonas campestris pv. campestris and Pseudomonas putida.


Input: Serum induction of a MEF2 reporter gene was not observed in a line of NIH 3T3 cells which contain low MEF2 site binding activity.

MEF2 reporter gene

MEF2 site


Input: Since AP-1 is an important mediator of tumor promoter action, these findings may explain the anti-tumor-promoting activity of phenolic antioxidants.


Input: The second complex, when purified, contained four protein components including the 36-kDa protein.


Input: The study was repeated after administration of oral amiodarone, 50 mg/kg/day for 2 days in 8 divided doses (mean dose 6. 9 +/-0. 4 g).


Input: The other two clones, Ash-m and-s, had nucleotide sequences identical with Ash-l cDNA in the amino-terminal region.

Ash-m and-s

Ash-l


Input: MATERIAL AND METHODS: Of the 17 men and 17 women, who were 21 to 80 years of age, 27 had hereditary motor and sensory neuropathy type I and 7 had acquired demyelinating polyneuropathy.


Input: Muscle GSH-Px activity after prolonged exercise, training, and selenium supplementation.

Muscle GSH-Px


Input: We found that PML was expressed at a lower level in S, G2, and M phases and at a significantly higher level in G1 phase.

PML


Input: The roxithromycin doses that were chosen for these studies were less than achievable blood levels.


Input: We demonstrate here that the-DEDDDL sequence stabilizes GDP binding to Ran, and that the domain is required for high affinity interaction with a Ran-binding protein, HTF9A/RanBP1.

Ran

Ran-binding protein


Input: Serial followup strength data for 2 patients were compared to change in creatinine kinase (CK) levels.

creatinine kinase

CK


Input: Transfection of non-deleted expression vector into NIH3T3 cells results in acquisition of focus-forming activity while a deleted form of expression vector fails to show this activity even in the presence of basic FGF.

basic FGF


Input: All ribosomal protein (rp) gene promoters from Saccharomyces cerevisiae studied so far contain either (usually two) binding sites for the global gene regulator Rap1p or one binding site for another global factor, Abf1p.

ribosomal protein

rp


Input: CONCLUSION: The MTD for CPT-11 administered in a 3 consecutive-days-every-3 weeks schedule in this patient population is 115 mg/m2/day.


Input: Otte, Mol.


Input: A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression.


Input: A role for glycogen synthase kinase-3 in the control of gene expression.

glycogen synthase kinase-3


Input: Reconstitution of complexes containing p62 and the src family kinase p59fyn in HeLa cells demonstrated that complex formation resulted in tyrosine phosphorylation of p62 and was mediated by both the SH3 and SH2 domains of p59fyn.

src family kinase p59fyn

SH2 domains


Input: Protein cHMGI binds preferentially to AT-rich DNA with a half-saturation value of 1. 1 nM.

Protein cHMGI


Input: The U14 genes of mouse as well as rat, hamster, human, Xenopus and trout are encoded within introns of the constitutively expressed 70-kDa-cognate-heat-shock protein gene (hsc70).

U14 genes

70-kDa-cognate-heat-shock protein gene


Input: Inclusion in this family of proteins suggests that FliQ and FliR may participate in an export pathway required for flagellum assembly.

FliQ

FliR


Input: Coronary vasoconstriction caused by endothelin-1 is enhanced by ischemia-reperfusion and by norepinephrine present in concentrations typically observed after neonatal cardiopulmonary bypass.


Input: Atcys1, Athyp1, AKin10 and the ORF are very close to each other and organized in the same polarity; hence, the intergenic regions probably contain, within less than 0. 5 kb, all the regulatory elements necessary to govern initiation and termination of transcription.


Input: Southern blot hybridization experiments suggest the presence of one copy of Atcys1, Athyp1 and AKin10 per haploid genome, and Northern blot analysis demonstrates that the three genes are differentially expressed in roots, shoots and leaves.


Input: Between the subgroups of dementia disorders there were no significant differences in basal cortisol levels.


Input: Basal components of the transcription apparatus (RNA polymerase II, TATA-binding protein) contain activation domains: is the repetitive C-terminal domain (CTD) of RNA polymerase II a " portable enhancer domain "? Regions rich in serine, threonine, and proline residues can be found in transcriptional activation domains, as well as in the N-terminal parts of mammalian TATA-binding proteins, where they are interrupted by polyglutamine stretches.

RNA polymerase II

TATA-binding protein

RNA polymerase II

mammalian TATA-binding proteins


Input: Mutagenesis of IM1 enhances the ability of c-Fos to activate an AP1 bearing promoter.

c-Fos

AP1 bearing promoter


Input: Self or foreign cellular proteins provide peptides for presentation by major histocompatibility complex (MHC) class I molecules on the surface of antigen presenting cells (APC).

major histocompatibility complex (MHC) class I molecules


Input: However, cotransfection studies indicate that RVR does not activate transcription when this hormone response element is linked to a reporter gene but rather acts as a potent competitive repressor of ROR alpha function.

RVR

ROR alpha


Input: Molecular cloning and sequencing of a cDNA encoding SR beta revealed that SR beta is a transmembrane protein and, like SR alpha and SRP54, is a member of the GTPase superfamily.

SR beta

SR beta

SR alpha

GTPase superfamily


Input: To understand the function of receptor-linked tyrosine phosphatases in neural development, we sought to identify LAR isoforms preferentially expressed in the nervous system and cellular processes regulating LAR alternative splicing.

receptor-linked tyrosine phosphatases

LAR isoforms

LAR


Input: 135 students had a count of less than 50 eggs/10 ml. urine and 56 had more than 50 eggs/10ml.


Input: Chrispeels [1993] EMBO J 12: 2241-2247).


Input: The mRNAs of the GRF genes are encoded by six exons interrupted by five introns.

GRF genes


Input: A major task for sports scientists may be to verify empirically the nature of an integrated model of the sport performer.


Input: Removal of the GST domain from GST-Tax by thrombin restores Tax' s ability to assemble a ternary Tax-CREB-21-bp-repeat complex. (ABSTRACT TRUNCATED AT 400 WORDS)

GST domain

GST

Tax

thrombin

Tax

Tax

CREB


Input: Specific binding was not observed with either the orthologous rat or mouse fragments using human or rodent extracts.


Input: We have attempted to clone two recessive extragenic suppressors of such ts mutants (sdp1 for mutation pol3-14 and sdp5-1 for mutation pol3-11) by transforming thermoresistant haploid strains pol3-14 sdp1 and pol3-11 sdp5-1 with wild-type genomic libraries in singlecopy or multicopy vectors.

mutation pol3-14

mutation pol3-11

pol3-14 sdp1

pol3-11 sdp5-1


Input: In acute-phase livers, we observed a dramatic reduction in HNF-3 alpha expression which correlates with a decrease in the expression of its target gene, the TTR gene.

HNF-3 alpha

TTR gene


Input: Similarly, in mammalian cells PBP74 is synthesized as a pre-protein that requires membrane potential-dependent import into mitochondria for its maturation.


Input: The first open reading frame of the blueberry scorch carlavirus (BBScV) genome encodes a putative replication-associated protein of 223 kDa (p223).


Input: From sequence alignments with phylogenetically related viruses, including tymoviruses, we predicted that p223 contained a papain-like proteinase domain with a putative catalytic cysteine994 and histidine1075.

papain-like proteinase domain


Input: The p97-depleted nuclei remained largely competent for nuclear protein import.


Input: Using gel retardation assays with HepG2 nuclear extract, we demonstrated the presence of a specific protein which bound to the NRE fragment.


Input: Twenty-two consecutive patients with ischaemic ulcers had tcPO2 measured and the ankle/brachial (ABI) and toe/brachial (TBI) indices calculated.


Input: TcPO2 measurement appears to be a reliable technique that can influence ischaemic ulcer management.


Input: Expression of h6. 1 in COS-1 cells led to the production of a typical type IV PDE activity in that cAMP, but not cGMP, served as substrate and its activity was insensitive to either Ca2 +/CaM or cGMP but was inhibited by low concentrations of rolipram. (ABSTRACT TRUNCATED AT 400 WORDS)

type IV PDE

CaM


Input: The PSD2 gene was heterologously expressed by infection of Sf-9 insect cells with recombinant baculovirus, resulting in a 10-fold increase in PSD activity.

PSD2 gene

PSD


Input: Like Epo, HNF-4 is expressed in kidney, liver, and Hep3B cells but not in HeLa cells.

Epo


Input: Moreover, the hypoxia-induced expression of the endogenous Epo gene was significantly inhibited in Hep3B cells stably transfected with HNF-4 delta C.

Epo gene

HNF-4 delta C


Input: These observations indicate that there are multiple mechanisms by which an individual transcript can be degraded following deadenylation.


Input: Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Small Maf proteins

Fos

NF-E2 transcription factor


Input: Both factors demonstrated significant correlations with rCBF in the medial prefrontal cortex and frontal polar cortex while for each factor there were also unique patterns of correlations with posterior brain regions.


Input: The resulting integrated physical, genetic, and cytogenetic map constitutes a resource for the characterization of genes that may be involved in the WAGR syndrome.


Input: Three classes of test objects were considered: (1) a multicompartment test object for 31P MRS measurements performed with slice-selective sequences; (2) a two-compartment test object for volume-selection 1H MRS; and (3) two-compartment test objects for assessing the performance of experimental systems using ISIS as volume localization sequence in 31P MRS.


Input: Pregnancy screening by uterine artery Doppler velocimetry--which criterion performs best? OBJECTIVE: To test whether repeating Doppler studies of the uteroplacental circulation late in gestation will improve the test' s power for predicting pregnancy-induced hypertension and fetal growth restriction (FGR), and whether analysis based on a combination of quantitative and qualitative assessments of the uterine arterial waveforms will yield better results than analysis based on either alone.


Input: Analysis of disassociation rates indicates that the Grf10-Swi5-DNA complex has a longer half-life than protein-DNA complexes that contain only Swi5 or Grf10.


Input: The mutant allele of the alpha 1-tubulin gene was designated tua1-1.

alpha 1-tubulin gene


Input: Analysis of a set of deletion constructs in transient transfection assays measuring heterologous reporter gene (luciferase) activity demonstrated that the 182-bp 5'-flanking region provides full promoter activity in IL-2-stimulated L2 cells.

luciferase


Input: Northern analysis of RNA samples isolated from ammonium-grown cultures of the ntcA mutant showed reduced amounts of glnA message and the absence of a 1. 7-kb transcript.

ntcA mutant

glnA message


Input: In order to define potential candidate genes for inherited disorders characterized by aberrant gene expression, we utilized Kruppel-related sequences to isolate zinc finger-containing cDNAs.

Kruppel-related sequences


Input: The isolated POT1 clones hybridized to a 1. 4 kb RNA species, which was induced approximately 30-fold when oleate was the carbon source.


Input: The Y. lipolytica genomic POT1 gene was disrupted by replacing 120 bp of its coding sequence with 2. 7 kbp of DNA including the Y. lipolytica LEU2 gene.

LEU2 gene


Input: The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

Notch homologue mouse Notch 3

epidermal growth factor-repeats


Input: Immunoreactive AR content in transfected COS-1 cells was not influenced by exposure to 8-Br-cAMP.

AR


Input: Internal biliary drainage, unlike external drainage, does not suppress the regeneration of cholestatic rat liver after partial hepatectomy.


Input: ORF 2 potentially encoded a hydrophobic protein of 29, 705 Da with six potential membrane-spanning regions.


Input: Plasmids were constructed with the mouse promoter region linked to the reporter gene chloramphenicol acetyltransferase (CAT), and transiently and stably transfected in the INS-1 cells.

reporter gene chloramphenicol acetyltransferase

CAT


Input: Specifically, this study determined the influence of: (1) an awareness strategy, (2) a non-awareness strategy, (3) a Five-Step Approach strategy and (4) a control condition.


Input: Mutually exclusive interaction of the adenovirus E4-6/7 protein and the retinoblastoma gene product with internal domains of E2F-1 and DP-1.

adenovirus E4-6/7 protein

retinoblastoma gene product


Input: The transverse magnetization decays mentioned above exhibited two components, a T2 fast (T2f) and a T2 slow (T2s) component.


Input: Expression of a dominant-negative ras gene also blocks TIS10/PGS2 induction by v-src.

dominant-negative ras gene

v-src


Input: Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.

Tax

NF-kappa B

Rel

I kappa B alpha

RelA (p65)

c-rel gene


Input: These RZR subtypes represent members of a new family of orphan nuclear receptors that most likely regulate specific gene expression.

RZR

orphan nuclear receptors


Input: Interestingly, these response elements display dramatically reduced affinity for retinoic acid receptor-retinoid-X receptor heterodimers.

retinoic acid receptor

retinoid-X receptor


Input: Remarkably, U21 contains a long stretch (13 nt.) of complementarity to a highly conserved sequence in 28S rRNA.

28S rRNA


Input: These results provide evidence of a bypass of p53-induced Waf1/Cip1-mediated cell cycle regulatory pathways by a member of the myb oncogene family.

myb oncogene family


Input: All groups were challenged subsequently with naloxone (0. 4 mg/kg) in the distinctive environment and then observed for signs of opiate withdrawal.


Input: There were 9 patients in NYHA class III and 8 in class IV. (ABSTRACT TRUNCATED AT 250 WORDS)


Input: TG-day and TG-night were 19. 4 +/-6. 1%, 26. 6 +/-5. 3%, (750 mm3 < T.


Input: Ten volunteers were tested at 18, 000 ft (5, 486 m), and through 12, 000, 8, 000, and 5, 000 ft (3, 657, 2, 438, and 1, 524 m) with directional sounds recorded via a dummy head microphone and presented binaurally.


Input: Upon differentiation with retinoic acid (RA), transcription of the Rex-1 gene decreases rapidly.

Rex-1 gene


Input: In general, the filtration rate in relevant areas appears to be an integrative and easily determined parameter, reflecting hormonal and neurogenic vascular as well as local interstitial control of the Starling forces.


Input: Homozygous null embryos also displayed abnormalities in heart development, consistent with the conclusion that Tek is necessary for endocardial/myocardial interactions during development.

Tek


Input: A strong trithorax binding site was found at the cytological location of the fork head gene, a region-specific homeotic gene not located within a homeotic complex.

trithorax binding site

fork head gene

homeotic gene

homeotic complex


Input: C/EBP alpha also activates the promoter of the rat class-I ADH gene in a sequence-specific manner [Potter et al., Arch.

C/EBP alpha

rat class-I ADH gene


Input: C/EBP alpha also activates the promoter of the rat class-I ADH gene in a sequence-specific manner [Potter et al., Arch.

C/EBP alpha

rat class-I ADH gene


Input: Segments with more reduced BMIPP uptake than MIBI uptake (mismatching) showed either normal wall motion or demonstrated inotropic reserve during dobutamine stimulation.


Input: The present data also indicate that patients with TGBM nephropathy often have concomitant IgA nephropathy and mesangial proliferative glomerulonephritis.

IgA


Input: A full-length cDNA clone isolated from a rat lung library was predicted to encode a 55-kDa protein containing at its amino terminus a targeting domain that binds to the ANP-receptor kinase-like domain and containing at its carboxyl terminus a putative protein-serine phosphatase domain.

ANP-receptor kinase-like domain

protein-serine phosphatase


Input: A high-resolution restriction map of over 200 kb of contiguous DNA containing N-myc has been generated by subcloning YACs into cosmids.

N-myc


Input: In the present article, the causes of death or ill-being as found in 10 consecutive carcinogenicity studies--5 studies with 2400 OFA (Sprague-Dawley-derived) and Wistar rats and 5 studies with 2400 OF1 and NMRI mice--were re-examined.


Input: Surprisingly, Northern (RNA) blot analysis and reverse transcriptase-PCRs performed after transfection of COS-7 or HeLa cells with these viral RNAs revealed that Y88S and Y88L RNAs replicated at only very low levels.

reverse transcriptase

Y88L RNAs


Input: Moreover, the ability to selectivity arrest elongation by polIII at defined positions within the tRNA gene transcription unit has permitted the identification of discrete functional properties of paused mammalian polIII ternary complexes.

polIII

mammalian polIII ternary complexes


Input: A recent index (Fluorosis Risk Index) developed by Pendrys (1990) is also included in this review.


Input: The role of HIV tat, which is the main enhancing factor for viral LTR, in the regulation of IL-2 gene transcription has been studied following transient expression of the tat gene in phorbol ester and calcium ionophore-activated Jurkat cells transfected with IL-2 promoter-chloramphenicol acetyltransferase reporter constructs.

HIV tat

viral LTR

IL-2 gene

tat gene

chloramphenicol acetyltransferase


Input: Splice variations in genes coding for the transmembrane FGF receptor (FGFR) result in isoforms that vary in the ectodomain, intracellular juxtamembrane domain, and the intracellular kinase domain.

transmembrane FGF receptor

FGFR


Input: The git1, git3, git5, git7, git8 and git10 genes act upstream of adenylate cyclase, presumably encoding an adenylate cyclase activation pathway.

git10 genes

adenylate cyclase

adenylate cyclase


Input: Deletion studies identified a distal response element that is responsible for the cytokine response and has properties of an inducible transcriptional enhancer.


Input: No drop in oxygen saturation (SaO2) or visual evidence of transient electroencephalographic (EEG) arousals can be found at repeat polysomnography.


Input: This sequenced region of the V beta locus contains an average number of repetitive DNA elements (21 Alu, three L1, three MER, and three retrovirus-related elements.

Alu


Input: However, by an NS35-specific RNA capture assay, the multimers were shown to possess the RNA-binding activity previously demonstrated for NS35.

NS35-specific RNA


Input: Ketamine in the treatment of bronchospasm during mechanical ventilation.


Input: The molecular basis for commitment of progenitors to the eosinophil lineage and mechanisms by which eosinophil-specific genes are expressed and regulated during differentiation is unknown.


Input: Thus, YMIP is a functional homolog of RMIP and represents a new component of the yeast mitochondrial import machinery.

YMIP

RMIP


Input: Tryptic cleavage and peptide sequence analysis demonstrated that the 98-kD protein is identical to a recently cloned protein, special A-T-rich binding protein 1 (SATB1), that binds selectively to nuclear matrix/scaffold-associated regions of DNA (MARs/SARs).

special A-T-rich binding protein 1


Input: Heparin had no effect on rAC-st myosin light chain phosphatase activity, while the B subunit-containing forms were stimulated 2-3-fold.

rAC-st myosin light chain phosphatase


Input: BACKGROUND AND DESIGN: Fifty-nine melanocytic nevi with eccentric foci of hyperpigmentation (" small dark dots ") that measured primarily 1 to 2 mm in diameter were prospectively examined to determine the histologic correlates of the dark dots.


Input: A single NMSC was present in 69. 4%, two in 16%, three in 6. 4%, four in 3. 5%, five to nine in 4. 2%, and 0. 5% had ten or more.


Input: The two ParA proteins that are produced as a result of independent translation initiation at two different start codons within the same open reading frame were overexpressed in Escherichia coli and partially purified.

ParA proteins


Input: To get further insights into the molecular mechanisms that control tal-1 expression, we have isolated 5' sequences of the murine gene and compared them to their human counterparts.


Input: These results demonstrate that a diverse set of carboxyl-terminal sequence motifs and posttranslational modifications lead to functional Ras proteins in yeast.

Ras proteins


Input: Binding of U2 small nuclear ribonucleoprotein (snRNP) to the pre-mRNA is an early and important step in spliceosome assembly.

U2 small nuclear ribonucleoprotein


Input: Our results indicate that the KRAB domain present in the non-finger region of many ZFP genes quenches transcription possibly due to specific protein-protein interactions between the KRAB-A domain and components of the proximal transcriptional apparatus.

KRAB domain

ZFP genes

KRAB-A domain


Input: Marine oils and cardiovascular reactivity.


Input: Significant alterations in CBC results and serum CRP concentration, compared with baseline values, were lacking in dogs of the control group.

serum CRP


Input: The newly recognised skeletogenital syndrome.


Input: Ras-and ultra-violet-responsive protein kinases that phosphorylate c-Jun on serine residues at positions 63 and 73 and stimulate its transcriptional activity have been identified.

Ras-and ultra-violet-responsive protein kinases

c-Jun


Input: A short sequence surrounding the major JNK phosphorylation site of c-Jun is conserved in c-Fos and is part of its activation domain, suggesting that c-Fos may be similarly regulated.

JNK

c-Jun

c-Fos

c-Fos


Input: c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK.

c-Fos

H-Ras-activated protein kinase

JNK

ERK


Input: Essential features of this model are bending of the DNA double helix and contact of operator sites with repressor domains bearing sequence homologies with the helix-turn-helix (HTH) motifs of other DNA-binding proteins.


Input: The binding of transcription factor AP-1 and vitamin D receptor (VDR) to the composite AP-1 plus vitamin-D-responsive promoter region (AP-1 + VDRE) of the human osteocalcin gene was characterized in osteocalcin-producing (MG-63) and non-producing (U2-Os, SaOs-2) human osteosarcoma cell lines.

vitamin D receptor

VDR

AP-1 plus vitamin-D-responsive promoter

AP-1 + VDRE

human osteocalcin gene

osteocalcin


Input: The LTR-binding activities of VBP, a1/EBP, and B-cell nuclear extract protein were compared and mapped by gel shift, DNase I footprinting, and methylation interference assays.

VBP

B-cell nuclear extract protein

DNase I


Input: These results suggest that leader-mRNA fusion in coronavirus transcription does not require direct RNA-RNA interaction between complementary sequences.


Input: These results suggest that leader-mRNA fusion in coronavirus transcription does not require direct RNA-RNA interaction between complementary sequences.


Input: To determine whether P35 could activate the 39k promoter in the absence of IE1, the p35 open reading frame was cloned under the control of the ie1 promoter.

ie1 promoter


Input: In addition, a microsatellite repeat polymorphism with a heterozygosity of 71% at the RET locus and a restriction fragment length polymorphism with a heterozygosity of 42% detected by a lambda clone from the D10S94 locus have been developed for high-resolution genetic linkage mapping and predictive diagnostic testing.

RET locus

D10S94 locus


Input: However, tyrA can be expressed efficiently from an internal promoter which appears to lie within the 3' portion of aroF.

tyrA

aroF


Input: Within the span of attenuator region encoding the three stem-loop structures of mRNA secondary configuration, hot spots of base-residue divergence were localized to looped-out regions.


Input: Previous studies showed that mutations in the 6K protein led to the slow release of aberrant, multi-cored infectious virions.


Input: The RFLP patterns of the isolates from six of these patients remained essentially unchanged (two strains showed one additional band) despite the development of drug resistance.


Input: Southern analysis on genomic DNA isolated from tissues and cell lines from several mouse strains using mCD22 cDNA demonstrated that the Cd22 locus encoding mCD22 is a single copy gene of < or = 30 kb.

mCD22 cDNA

Cd22 locus


Input: The tyrosine hydroxylase gene (TH) contains a single copy of a consensus CRE at-45 to-38 base pair (bp) upstream of the transcription initiation site.

tyrosine hydroxylase gene

TH


Input: Fenoldopam, a dopamine receptor agonist, has been shown, in animal experiments, to improve renal perfusion.

dopamine receptor


Input: The results indicate that hrpRS and hrpL are part of a regulatory cascade in which HrpR and HrpS activate expression of hrpL and HrpL, a putative sigma factor, induces expression of HrpL-responsive genes.

hrpRS

hrpL

HrpR

HrpS

hrpL

HrpL

sigma factor

HrpL-responsive genes


Input: All other normal and transformed lymphoid and nonlymphoid cell lines and normal tissues were negative for PANG expression except for the brain, wherein unique 4. 0-and 6. 1-kb transcripts were detected.

PANG


Input: L., Greer, J. & Carter, G.


Input: Western blotting (immunoblotting) with an antiserum to a partial SOD expressed in Escherichia coli revealed two proteins with estimated molecular masses of 19 and 29 kDa.

SOD


Input: Members of the myocyte-specific enhancer-binding factor 2 (MEF2) family of transcription factors bind a conserved A/T-rich sequence in the control regions of numerous muscle-specific genes.

myocyte-specific enhancer-binding factor 2


Input: Seven of these had counterparts in the US of herpes simplex type 1 (HSV-1), pseudorabies virus (PRV), and equine herpesvirus type 1 (EHV-1).


Input: The previously described enhanced translation of spinach L12 mRNA from its two tandem AUG codons and the two functional rpl12 genes in Arabidopsis probably provide two mechanisms for generating the four copies of L12/chloroplast ribosome, qualitatively different from those attempted in eubacteria.

L12 mRNA

rpl12 genes

L12/chloroplast ribosome


Input: Genomic DNA clones containing the T-cell-specific human MAL gene were isolated.

T-cell-specific human MAL gene


Input: Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters.

furin


Input: Certain spt10 spontaneous alleles are good suppressors but have a normal growth rate, suggesting that the SPT10 protein may have two distinct functions.

SPT10 protein


Input: In Rat 1a cells, m1R stimulation of phospholipase C beta and the marked rise in intracellular calcium stimulated cyclic AMP (cAMP) synthesis, resulting in the activation of protein kinase A.

phospholipase C beta

protein kinase A


Input: The mutations did not affect the repression of CPA1 by arginine.


Input: A segment of mRNA encoding the leader peptide of the CPA1 gene confers repression by arginine on a heterologous yeast gene transcript.

CPA1 gene


Input: Structure and expression of the alternative sigma factor, RpoN, in Rhodobacter capsulatus; physiological relevance of an autoactivated nifU2-rpoN superoperon.

sigma factor

RpoN

rpoN


Input: Insertion of short oligonucleotides encoding the basic amino acid motifs 726-GRKRKSP-732 from IE175 and 500-VRPRKRR-506 from IE110 into deleted cytoplasmic forms of the two proteins restored the karyophilic phenotype and confirmed that these motifs are both necessary and sufficient for proper nuclear localization.


Input: Mapping of intracellular localization domains and evidence for colocalization interactions between the IE110 and IE175 nuclear transactivator proteins of herpes simplex virus.


Input: The revertant TATA boxes accelerated the kinetics of HIV replication when present in the context of an LTR containing a Sp1 mutation (deletion or site specific); no effect was observed on the infectivity of wild-type HIV.


Input: Mitochondrial Mas70p signal anchor sequence.

Mitochondrial Mas70p signal anchor sequence


Input: Response to treatment was better in patients with less pretreatment (one-two prior treatments) than in heavily pretreated ones (more than three) and this relation was found to be statistically significant (p < 0. 05).


Input: The class II Escherichia coli alanine tRNA synthetase aminoacylates RNA miniduplexes, which reconstruct the acceptor end of alanine tRNA with the critical G3: U70 base pair.

class II Escherichia coli alanine tRNA synthetase aminoacylates RNA miniduplexes

alanine tRNA


Input: A second study group, with intact cardiac innervation, consisted of 19 patients with stable angina pectoris class I to III.


Input: Thus, we have separated the signal function from the anchor function of the 6. 7K SA domain.


Input: Exposure to higher TPA concentrations decreased the content of these transcripts.


Input: Our results indicate that the minimal requirements for induction of PEPCK by PKA and inhibition by insulin include: 1) the CREB activation domain, 2) the PEPCK TATA sequence, and 3) insulin-responsive hepatoma cells.

PEPCK

PKA

insulin

CREB activation domain

PEPCK TATA sequence

insulin


Input: Topical L-NNA attenuated the hypercapnic increase of CoBF by 52 +/-6% and CeBF by 29 +/-5% after 45-min exposure.


Input: Restriction analysis and Southern hybridization revealed the presence of Tn5422 in all the plasmid-mediated cadmium-resistant L. monocytogenes strains tested but not in strains encoding cadmium resistance on the chromosome.


Input: The 7-day treatment resulted in a decrease in mitochondrial uptake of Rh123 and an increase in NAO uptake.


Input: Thrombotic thrombocytopenic purpura in systemic lupus erythematosus.


Input: Women' s opportunities for paid work outside the home are constrained by their role as primary carer within the family, writes Trudy Wynne.


Input: Interestingly, the interaction of ZAP-70 with the motif was dependent on the presence of both ZAP-70 SH2 domains and both of the tyrosine residues in the motif, suggesting that ZAP-70 interacts with two phosphotyrosine residues and that the binding of the two SH2 domains is cooperative.

ZAP-70 SH2 domains

SH2 domains


Input: PRL-1 is able to dephosphorylate phosphotyrosine substrates, and mutation of the active-site cysteine residue abolishes this activity.


Input: 50 kDa and 130-170 kDa were detected.


Input: This strategy was used to place both the Tn903 neo gene and the Rhodosporidium toruloides phenylalanine ammonia lyase (PAL)-encoding gene under the transcriptional control of pPGK:: REP2.

Tn903 neo gene

Rhodosporidium toruloides phenylalanine ammonia lyase

PAL

pPGK


Input: In the case of congenital protein C deficiency, vitamin K antagonists must be started cautiously due to the risk of skin necrosis.

protein C


Input: In addition, we observe that the hUBF-promoter interaction is highly sensitive to the antagonistic effects of cisplatin-DNA adducts.

hUBF-promoter


Input: Simultaneous, bilateral and permanent ventilation with a diaphragm pacing in childhood: the implantation technique and indications


Input: The pyrR and pyrP genes encoded polypeptides with calculated molecular masses of 19. 9 and 45. 2 kDa, respectively.

pyrR

pyrP genes


Input: To identify the precise location of the phosphorylation site on the 64-kDa protein, a step-by-step mutagenesis procedures was followed.


Input: Co-transfection of a tat expressing plasmid with these viruses containing the tat ORF mutations resulted in higher levels of virus production demonstrating that the effects of both mutants are tat specific.

tat

tat ORF


Input: Analysis of the gag and rev proteins in the transfected cells demonstrated that these proteins were not detectable in cells transfected with the tat mutants but could be readily detected when the mutations were complemented in trans with a tat expression vector.

gag

rev proteins

tat mutants


Input: SIN-1 had no influence on either the ischemic parameters in the surface electrocardiogram (ECG) or the intracoronary ECG.


Input: Stimulation of [3H] PA production upon CD3 cross-linking was 77% lower in permeabilized CD45-cells than in CD45 + cells, consistent with the reduced activity of p59fyn in CD45-cells.

CD45 +


Input: A Dictyostelium transformant overexpressing DdPTPa does not develop normally.

DdPTPa


Input: We postulate that CaM binding by HIV envelope proteins is likely to exert diverse modulatory effects, and the mechanism for HIV-induced cytotoxicity may involve, in part, inhibition of CaM-regulated cellular functions.

CaM

HIV envelope proteins

CaM


Input: There was no apparent effect of growth temperature on the steady-state levels of fad7 mRNA in wild type plants.

fad7 mRNA


Input: A second important molecule in TCR signal transduction is the guanine nucleotide binding protein, p21ras, which is coupled to the TCR by a protein tyrosine kinase dependent mechanism.

TCR

guanine nucleotide binding protein

TCR

protein tyrosine kinase


Input: A series of 5'-deletions revealed that the fragment-218 to + 4 from the TSS had the highest promoter activity, nearly 1000-fold greater than the promoterless chloramphenicol acetyltransferase construct.

chloramphenicol acetyltransferase construct


Input: The lemdr1 gene was cloned in the expression vector pALTNEO and transfected into wild-type L. enriettii and the resulting transfected cells were resistant to vinblastine but at lower levels than in the selected mutant cells.

lemdr1 gene


Input: The bioavailability of etodolac from capsules exposed to stressed conditions was compared in both dogs and humans to capsules stored at RT conditions.


Input: As regards lipid metabolism, the mean values for total triglycerides, cholesterol, LDL-cholesterol and HDL-cholesterol seen at the end of five years of Norplant-2 rod use and six months postremoval were similar to the preinsertion mean.

LDL-cholesterol

HDL-cholesterol


Input: To our knowledge this is the first case in which a probable association between cholelithiasis and Wildervanck' s syndrome has been recorded.


Input: Addition of phalloidin-stabilized F-actin nuclei and phalloidin restored L266D actin' s ability to polymerize at 4 degrees C.

F-actin

actin


Input: Northern (RNA) analysis demonstrated expression of human PI 3-kinase in all tissues and cell lines tested.

PI 3-kinase


Input: These results demonstrate the existence of different PI 3-kinase isoforms and define a family of genes encoding distinct PI 3-kinase catalytic subunits that can associate with p85.

PI 3-kinase isoforms

PI 3-kinase catalytic subunits


Input: One complex most likely contained Sp1, and another complex showed S-phase-specific binding, suggesting a direct role in the cell-cycle-dependent R1 gene expression.

R1 gene


Input: The rate of enzymic stimulation induced by a given nitrate correlates closely with the rate of measured NO production from the nitrate molecule.


Input: Two patients were treated successfully with a combination of metronidazole (a tissue amoebicide) and diloxanide (a lumenal amoebicide).


Input: We have identified in the 5' untranslated region of the Drosophila copia retrotransposon, 3' to the left LTR, a sequence for transcriptional regulation by homeoproteins.

Drosophila copia retrotransposon


Input: By using the full-length cytoplasmic domain and mutants with progressive carboxy-terminal deletions, internal deletions, or point mutations, we identified the first 150 amino acid residues of LIFR as the minimal region necessary for signaling.

LIFR


Input: Oligonucleotide competitors were used to evaluate the accessibility of the TATA-binding site in TIF-IB, TFIID, and TFIIIB.

TIF-IB

TFIID

TFIIIB


Input: The 227-to-239 region blocked ADR1 activity independently of the TAD present on ADR1, ADR1 DNA binding, and specific ADH2 promoter sequences.

TAD

ADH2 promoter sequences


Input: TGF beta 1 expression is largely governed by three AP-1 binding sites located in two different promoters of this gene.

TGF beta 1

AP-1 binding sites


Input: Repeated administration of GRg2 20 mg/kg i. p. significantly improved the CYP-induced recognitional deficits by increasing the CYP-decreased rate from 55. 8 +/-9. 6 to 80. 8 +/-4. 2 in d 3 learning acquisition (F (1, 14) = 5. 6, p < 0. 05), from 53. 4 +/-8. 4 to 60. 0 +/-8. 2 in 48 h memory acquisition (F (1, 14) = 7. 5, p < 0. 05) and from 55. 0 +/-5. 5 to 88. 3 +/-2. 5 in 24 h memory retention (F (1, 12) 27. 5, p < 0. 01) as well as from 60. 0 +/-6. 8 to 85. 6 +/-6. 9 in 48 h memory retrieval (F (1, 12) = 5. 2, p < 0. 05), respectively.


Input: The therapeutic action of cyclosporin A (Sandimmun): its application in rheumatoid arthritis.


Input: Pentazocine analgesia: is there a niche for Talwin Nx? Pentazocine can be a useful analgesic agent for the management of acute dental pain.


Input: In addition, REP21 plants were resistant to an unusually broad range of tobamoviruses including tomato mosaic virus, tobacco mild green mosaic virus, TMV-U5, green tomato atypical mosaic virus, and ribgrass mosaic virus.


Input: In our studies, we utilized HIV-1 HXB2 and HIV-1 Z2Z6 core enhancers because the Z2Z6 strain has a single point mutation flanking the right ETS-binding site.

Z2Z6 core enhancers

ETS-binding site


Input: Because of the small number of visceral angiography procedures performed (38), no definitive conclusions could be drawn as to the differences between ionic and nonionic agents regarding grade-2 and grade-3 adverse events.


Input: The Stryker frame modification to the standard Dornier HM3 lithotriptor allows for improved visualization and easier localization of distal ureteral calculi compared to the standard gantry.


Input: Glomerular mesangial cells expressed an abundant 1. 1 kb mRNA transcript for Id1, but in contrast to other cell types Id1 mRNA was expressed in both randomly cycling cells and in serum-deprived, quiescent cultures.

Id1 mRNA


Input: A single 1. 8-kb transcript mRNA was detected by Northern (RNA) blot analysis, and its 5' end maps to a position 51 bp upstream from the site of initiation of protein synthesis.


Input: The sequence similarity has suggested that SCG10 and stathmin have been derived from structurally and evolutionarily related genes.

stathmin


Input: These data are consistent with the idea that the neuron-specific SCG10 gene evolved by duplication and modification of the more broadly expressed stathmin/Lap18 gene.

neuron-specific SCG10 gene

stathmin


Input: We found that T3 (10 (-8) M) selectively stimulates transcription from rGH-TRE-and TREpal-, but not ME-TRE-and F2-TRE-, containing templates in which these TREs are linked in front of the rGH minimal promoter containing only the TATA box binding protein, but not any other proximal binding protein, sequence.

rGH

rGH minimal promoter

TATA box binding protein