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15/02/2021 | Efficacy of interpersonal psychotherapy for post-traumatic stress disorder: A systematic review and meta-analysis. | Evidence for the efficacy of treatments for post-traumatic stress disorder (PTSD) is urgently required. This systematic review and meta-analysis examines the efficacy of interpersonal psychotherapy (IPT) in reducing the symptoms of PTSD. Five databases were searched from inception until November 2018 to identify random... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Interpersonal Psychotherapy', 'Psychotherapy', 'Stress Disorders, Post-Traumatic', 'Treatment Outcome', 'Waiting Lists'] | 32,056,763 | 0 | Efficacy of interpersonal psychotherapy for post-traumatic stress disorder: A systematic review and meta-analysis. Evidence for the efficacy of treatments for post-traumatic stress disorder (PTSD) is urgently required. This systematic review and meta-analysis examines the efficacy of interpersonal psychotherapy (IPT) i... |
20/06/2022 | Uric Acid and Diabetic Retinopathy: A Systematic Review and Meta-Analysis. | The relationship between uric acid (UA) and diabetic retinopathy (DR) remains ambiguous, and the results of current studies on the UA levels in patients with DR are conflicting. A meta-analysis was performed to provide a better understanding of the relationship between UA levels and DR. PubMed, Web of Science, Embase, ... | ['Meta-Analysis', 'Systematic Review'] | ['Biomarkers', 'Diabetes Mellitus', 'Diabetic Retinopathy', 'Humans', 'Prospective Studies', 'Severity of Illness Index', 'Uric Acid'] | 35,712,295 | 0 | Uric Acid and Diabetic Retinopathy: A Systematic Review and Meta-Analysis. The relationship between uric acid (UA) and diabetic retinopathy (DR) remains ambiguous, and the results of current studies on the UA levels in patients with DR are conflicting. A meta-analysis was performed to provide a better understanding of ... |
04/04/2023 | Breast cancer liver metastases: systematic review and time to event meta-analysis with comparison between available treatments. | The current gold standard treatment for breast cancer liver metastases (BCLM) is systemic chemotherapy and/or hormonal therapy. Nonetheless, greater consideration has been given to local therapeutic strategies in recent years. We sought to compare survival outcomes for available systemic and local treatments for BCLM, ... | ['Systematic Review', 'Meta-Analysis', 'Journal Article'] | ['Humans', 'Female', 'Breast Neoplasms', 'Prospective Studies', 'Liver Neoplasms', 'Treatment Outcome', 'Hepatectomy', 'Melanoma, Cutaneous Malignant'] | 35,175,853 | 0 | Breast cancer liver metastases: systematic review and time to event meta-analysis with comparison between available treatments. The current gold standard treatment for breast cancer liver metastases (BCLM) is systemic chemotherapy and/or hormonal therapy. Nonetheless, greater consideration has been given to local thera... |
30/09/2022 | Five Years of Sacubitril/Valsartan-a Safety Analysis of Randomized Clinical Trials and Real-World Pharmacovigilance. | In PARADIGM-HF, sacubitril/valsartan showed a significant reduction in mortality and hospitalization for patients with heart failure with reduced ejection fraction. Despite proven efficacy, sacubitril/valsartan has moderate uptake in clinical practice. This study explores the safety profile of sacubitril/valsartan by c... | ['Journal Article', 'Meta-Analysis'] | ['Aminobutyrates', 'Angioedema', 'Angiotensin Receptor Antagonists', 'Angiotensin-Converting Enzyme Inhibitors', 'Biphenyl Compounds', 'Drug Combinations', 'Heart Failure', 'Humans', 'Hyperkalemia', 'Hypotension', 'Kidney Diseases', 'Pharmacovigilance', 'Randomized Controlled Trials as Topic', 'Stroke Volume', 'Tetrazo... | 34,125,356 | 1 | Five Years of Sacubitril/Valsartan-a Safety Analysis of Randomized Clinical Trials and Real-World Pharmacovigilance. In PARADIGM-HF, sacubitril/valsartan showed a significant reduction in mortality and hospitalization for patients with heart failure with reduced ejection fraction. Despite proven efficacy, sacubitril/va... |
06/12/2019 | The Influence of Conflicts of Interest on Outcomes in the Lumbar Disc Arthroplasty Literature: A Systematic Review. | A systematic review. The aim of this study was to determine the association between study outcomes and the presence of a conflict of interest (COI) in the lumbar disc arthroplasty (LDA) literature. Previous studies have evaluated the efficacy of LDA as a surgical alternative to arthrodesis. As investigators may have fi... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Arthroplasty', 'Conflict of Interest', 'Databases, Factual', 'Disclosure', 'Fees and Charges', 'Humans', 'Intervertebral Disc Degeneration', 'Intervertebral Disc Displacement', 'Outcome Assessment, Health Care', 'Research Personnel', 'United States'] | 31,374,001 | 0 | The Influence of Conflicts of Interest on Outcomes in the Lumbar Disc Arthroplasty Literature: A Systematic Review. A systematic review. The aim of this study was to determine the association between study outcomes and the presence of a conflict of interest (COI) in the lumbar disc arthroplasty (LDA) literature. Previo... |
27/07/2023 | Natural History of Non-Functioning Pituitary Adenomas: A Systematic Review and Meta-Analysis. | The management of non-functioning pituitary tumors (NFPTs) relies on the risk of tumor growth and new endocrinopathies. The objective of this systematic review was to assess the risk of growth, new pituitary endocrinopathies, and surgery in patients with conservatively treated NFPTs. We conducted a bibliographical sear... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Pituitary Neoplasms', 'Adenoma', 'Cohort Studies', 'Pituitary Gland'] | 37,494,058 | 0 | Natural History of Non-Functioning Pituitary Adenomas: A Systematic Review and Meta-Analysis. The management of non-functioning pituitary tumors (NFPTs) relies on the risk of tumor growth and new endocrinopathies. The objective of this systematic review was to assess the risk of growth, new pituitary endocrinopathies, ... |
27/11/2023 | Seroprevalence and potential risk factors of brucellosis in sheep from America, Africa and Asia regions: A systematic review and meta-analysis. | Brucellosis, a neglected and global zoonotic disease, infect a variety of mammals, among which sheep are one of the main hosts. This disease results in huge economic losses and is a widespread concern around the world. Based on the selection criteria, 40 articles from 2010 to 2021 of five databases (CNKI, Wanfang, VIP,... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Pregnancy', 'Female', 'Animals', 'Sheep', 'Seroepidemiologic Studies', 'Goats', 'Sheep Diseases', 'Goat Diseases', 'Brucellosis', 'Risk Factors', 'Asia', 'Africa', 'Animal Husbandry'] | 37,866,007 | 0 | Seroprevalence and potential risk factors of brucellosis in sheep from America, Africa and Asia regions: A systematic review and meta-analysis. Brucellosis, a neglected and global zoonotic disease, infect a variety of mammals, among which sheep are one of the main hosts. This disease results in huge economic losses and... |
27/04/2020 | Stage-Specific Sensitivity of Fecal Immunochemical Tests for Detecting Colorectal Cancer: Systematic Review and Meta-Analysis. | Fecal immunochemical tests (FITs) detect the majority of colorectal cancers (CRCs), but evidence for variation in sensitivity according to the CRC stage is sparse and has not yet been systematically synthesized. Thus, our objective was to systematically review and summarize evidence on the stage-specific sensitivity of... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Biomarkers, Tumor', 'Colonoscopy', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Feces', 'Humans', 'Immunochemistry', 'Neoplasm Staging'] | 31,850,933 | 0 | Stage-Specific Sensitivity of Fecal Immunochemical Tests for Detecting Colorectal Cancer: Systematic Review and Meta-Analysis. Fecal immunochemical tests (FITs) detect the majority of colorectal cancers (CRCs), but evidence for variation in sensitivity according to the CRC stage is sparse and has not yet been systemati... |
09/05/2024 | Dyslipidemia among adult HIV patients on antiretroviral therapy and its association with age and body mass index in Ethiopia: A systematic review and meta-analysis. | Dyslipidemia is a common public health problem in people living with human immunodeficiency virus (HIV) who are receiving antiretroviral therapy and increases the risk of cardiovascular disease. Although evidence indicates that the prevalence of dyslipidemia is high, estimated pooled data are not well documented. There... | ['Journal Article', 'Systematic Review', 'Meta-Analysis'] | ['Humans', 'Dyslipidemias', 'Ethiopia', 'HIV Infections', 'Body Mass Index', 'Adult', 'Prevalence', 'Age Factors', 'Triglycerides'] | 38,722,964 | 0 | Dyslipidemia among adult HIV patients on antiretroviral therapy and its association with age and body mass index in Ethiopia: A systematic review and meta-analysis. Dyslipidemia is a common public health problem in people living with human immunodeficiency virus (HIV) who are receiving antiretroviral therapy and increa... |
22/10/2020 | Impact of Renal Hilar Control on Outcomes of Robotic Partial Nephrectomy: Systematic Review and Cumulative Meta-analysis. | During robotic partial nephrectomy (RPN), various techniques of hilar control have been described, including on-clamp, early unclamping, selective/super-selective clamping, and completely-unclamped RPN. To evaluate the impact of various hilar control techniques on perioperative, functional, and oncological outcomes of ... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Constriction', 'Humans', 'Kidney', 'Kidney Neoplasms', 'Nephrectomy', 'Robotic Surgical Procedures', 'Treatment Outcome'] | 29,422,419 | 1 | Impact of Renal Hilar Control on Outcomes of Robotic Partial Nephrectomy: Systematic Review and Cumulative Meta-analysis. During robotic partial nephrectomy (RPN), various techniques of hilar control have been described, including on-clamp, early unclamping, selective/super-selective clamping, and completely-unclamped ... |
28/06/2022 | Feasibility, safety, and effectiveness of adult-sized instruments in pediatric percutaneous nephrolithotomy: A systematic review and meta-analysis. | Little evidence exists regarding the benefits and disadvantages of adult-sized instruments for Percutaneous Nephrolithotomy (PCNL) in pediatric patients. This systematic review aims to clarify the safety and efficacy of this approach. We conducted a systematic literature review using databases of PubMed, Scopus, Embase... | ['Journal Article', 'Meta-Analysis', 'Review', 'Systematic Review'] | ['Adult', 'Child', 'Feasibility Studies', 'Humans', 'Kidney Calculi', 'Nephrolithotomy, Percutaneous', 'Nephrostomy, Percutaneous', 'Reproducibility of Results', 'Retrospective Studies', 'Treatment Outcome'] | 35,534,382 | 1 | Feasibility, safety, and effectiveness of adult-sized instruments in pediatric percutaneous nephrolithotomy: A systematic review and meta-analysis. Little evidence exists regarding the benefits and disadvantages of adult-sized instruments for Percutaneous Nephrolithotomy (PCNL) in pediatric patients. This systematic re... |
22/05/2023 | The evidence framework of traditional Chinese medicine injection (Aidi injection) in controlling malignant pleural effusion: A clustered systematic review and meta-analysis. | Aidi injection (Aidi), a traditional Chinese medicine injection, is often practiced to control malignant pleural effusion (MPE). We performed a registered systematic review and meta-analysis (PROSPERO: CRD42022337611) to clarify the clinical role of Aidi in MPE, reveal optimal combinations of Aidi and chemical agents, ... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Lung Neoplasms', 'Medicine, Chinese Traditional', 'Pleural Effusion, Malignant', 'Drugs, Chinese Herbal', 'Cisplatin'] | 37,149,965 | 1 | The evidence framework of traditional Chinese medicine injection (Aidi injection) in controlling malignant pleural effusion: A clustered systematic review and meta-analysis. Aidi injection (Aidi), a traditional Chinese medicine injection, is often practiced to control malignant pleural effusion (MPE). We performed a re... |
15/04/2024 | Global burden of depression or depressive symptoms in children and adolescents: A systematic review and meta-analysis. | Depression is the leading cause of health-related disability. A proportion of depression cases begin in childhood and increase dramatically during adolescence. This systematic review and meta-analysis aimed to estimate the global prevalence of depression or depressive symptoms in children and adolescents and explore th... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Child', 'Humans', 'Adolescent', 'Depression', 'Depressive Disorder, Major', 'Prevalence', 'Databases, Factual'] | 38,490,591 | 0 | Global burden of depression or depressive symptoms in children and adolescents: A systematic review and meta-analysis. Depression is the leading cause of health-related disability. A proportion of depression cases begin in childhood and increase dramatically during adolescence. This systematic review and meta-analysis ... |
13/10/2020 | Mobile technologies to support healthcare provider to healthcare provider communication and management of care. | The widespread use of mobile technologies can potentially expand the use of telemedicine approaches to facilitate communication between healthcare providers, this might increase access to specialist advice and improve patient health outcomes. To assess the effects of mobile technologies versus usual care for supporting... | ['Journal Article', 'Meta-Analysis', "Research Support, Non-U.S. Gov't", 'Systematic Review'] | ['Adult', 'Bias', 'Cell Phone', 'Community Health Workers', 'Computer Security', 'Dermatologists', 'Diabetic Retinopathy', 'Emergency Service, Hospital', 'Guideline Adherence', 'Health Care Costs', 'Health Personnel', 'Health Status', 'Humans', 'Patient Satisfaction', 'Personal Satisfaction', 'Primary Health Care', 'Qu... | 32,813,281 | 1 | Mobile technologies to support healthcare provider to healthcare provider communication and management of care. The widespread use of mobile technologies can potentially expand the use of telemedicine approaches to facilitate communication between healthcare providers, this might increase access to specialist advice an... |
22/06/2021 | Cardiac amyloidosis imaging with amyloid positron emission tomography: A systematic review and meta-analysis. | Recent progress in amyloid positron emission tomography (PET) has enabled the targeted imaging of cardiac amyloidosis with accuracy. We performed a systematic review and meta-analysis on the diagnostic performance of cardiac amyloidosis using amyloid PET. A systematic search was performed using key words: cardiac amylo... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Amyloid', 'Amyloid Neuropathies, Familial', 'Heart Diseases', 'Humans', 'Positron-Emission Tomography', 'Sensitivity and Specificity'] | 30,022,405 | 0 | Cardiac amyloidosis imaging with amyloid positron emission tomography: A systematic review and meta-analysis. Recent progress in amyloid positron emission tomography (PET) has enabled the targeted imaging of cardiac amyloidosis with accuracy. We performed a systematic review and meta-analysis on the diagnostic performa... |
24/01/2024 | Comparison of the efficacy of Oxford unicondylar replacement for the treatment of spontaneous osteonecrosis of the knee versus medial knee osteoarthritis: a meta-analysis. | Meta-analysis of the comparative efficacy of Oxford unicompartmental knee arthroplasty (OUKA) for the treatment of spontaneous osteonecrosis of the knee (SONK) and medial knee osteoarthritis (MKOA). A computerized search was conducted for literature related to OUKA treatments of SONK and MKOA across various databases, ... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Joint Dislocations', 'Knee Joint', 'Osteoarthritis, Knee', 'Osteonecrosis', 'Pain, Postoperative'] | 38,254,108 | 0 | Comparison of the efficacy of Oxford unicondylar replacement for the treatment of spontaneous osteonecrosis of the knee versus medial knee osteoarthritis: a meta-analysis. Meta-analysis of the comparative efficacy of Oxford unicompartmental knee arthroplasty (OUKA) for the treatment of spontaneous osteonecrosis of the ... |
17/09/2020 | [Systematic review on efficacy and safety of Lanqin Oral Liquid in treatment of hand, foot and mouth disease]. | Lanqin Oral Liquid is a Chinese patent medicine which contains Isatidis Radix, Scutellariae Radix, Gardeniae Fructus, Phellodendri Chinensis Cordex and Sterculiae Lychophorae Semen. It is known for the pharmaceutical effect on the upper respiratory tract infection as it is beneficial for relieving the swelling of phary... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Drugs, Chinese Herbal', 'Hand, Foot and Mouth Disease', 'Humans', 'Medicine, East Asian Traditional', 'Nonprescription Drugs', 'Research Design'] | 32,893,543 | 0 | [Systematic review on efficacy and safety of Lanqin Oral Liquid in treatment of hand, foot and mouth disease]. Lanqin Oral Liquid is a Chinese patent medicine which contains Isatidis Radix, Scutellariae Radix, Gardeniae Fructus, Phellodendri Chinensis Cordex and Sterculiae Lychophorae Semen. It is known for the pharmac... |
16/02/2021 | Factors impacting on retention, success and equitable participation in clinical academic careers: a scoping review and meta-thematic synthesis. | To examine and synthesise current evidence on the factors that affect recruitment, retention, participation and progression within the clinical academic pathway, focusing on equitable participation across protected characteristics including gender, ethnicity and sexual orientation. Scoping review and meta-thematic synt... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Career Choice', 'Ethnicity', 'Faculty', 'Health Occupations', 'Humans', 'Leadership', 'Mentors', 'Personnel Selection', 'Qualitative Research', 'Sex Factors', 'Sexual and Gender Minorities', 'Universities'] | 32,213,518 | 0 | Factors impacting on retention, success and equitable participation in clinical academic careers: a scoping review and meta-thematic synthesis. To examine and synthesise current evidence on the factors that affect recruitment, retention, participation and progression within the clinical academic pathway, focusing on eq... |
01/02/2022 | Prognostic and Diagnostic Values of Novel Serum and Urine Biomarkers in Lupus Nephritis: A Systematic Review. | While renal biopsy remains the gold standard for diagnosing lupus nephritis (LN), the prognostic and diagnostic role of non-invasive biomarkers for LN is currently debated. Available studies published in last 5 years (2015-2020) assessing the diagnostic and prognostic value of urinary and/or serological biomarkers in s... | ['Journal Article', 'Systematic Review'] | ['Adiponectin', 'Biomarkers', 'Biopsy', 'Cytokine TWEAK', 'Hepatitis A Virus Cellular Receptor 1', 'Humans', 'Kidney', 'Lipocalin-2', 'Lupus Nephritis', 'Prognosis', 'Severity of Illness Index', 'Vascular Cell Adhesion Molecule-1'] | 34,515,043 | 1 | Prognostic and Diagnostic Values of Novel Serum and Urine Biomarkers in Lupus Nephritis: A Systematic Review. While renal biopsy remains the gold standard for diagnosing lupus nephritis (LN), the prognostic and diagnostic role of non-invasive biomarkers for LN is currently debated. Available studies published in last 5... |
04/01/2021 | Association Between Small Vessel Disease Markers, Medial Temporal Lobe Atrophy and Cognitive Impairment After Stroke: A Systematic Review and Meta-Analysis. | Two-thirds of stroke survivors suffer from cognitive impairment, and up to one-third of them progress to dementia. However, the underlying pathogenesis is complex and controversial. Recent evidence has found that cerebral small vessel disease (SVD) markers and the Alzheimer's disease (AD) neuroimaging marker medial tem... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Aged, 80 and over', 'Atrophy', 'Cerebral Small Vessel Diseases', 'Cognition', 'Cognitive Dysfunction', 'Female', 'Humans', 'Leukoencephalopathies', 'Male', 'Middle Aged', 'Neuroimaging', 'Predictive Value of Tests', 'Prognosis', 'Risk Assessment', 'Risk Factors', 'Stroke', 'Temporal Lobe'] | 33,227,579 | 0 | Association Between Small Vessel Disease Markers, Medial Temporal Lobe Atrophy and Cognitive Impairment After Stroke: A Systematic Review and Meta-Analysis. Two-thirds of stroke survivors suffer from cognitive impairment, and up to one-third of them progress to dementia. However, the underlying pathogenesis is complex ... |
05/10/2023 | Treatment of urge incontinence in postmenopausal women: A systematic review. | Urinary incontinence and other urinary symptoms tend to be frequent at menopause because of hormonal modifications and aging. Urinary symptoms are associated with the genitourinary syndrome of menopause which is characterized by physical changes of the vulva, vagina and lower urinary tract. The treatment strategies for... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Female', 'Humans', 'Urinary Incontinence, Urge', 'Urinary Incontinence, Stress', 'Postmenopause', 'Pelvic Floor', 'Urinary Incontinence', 'Estrogens', 'Cholinergic Antagonists', 'Randomized Controlled Trials as Topic'] | 37,791,545 | 0 | Treatment of urge incontinence in postmenopausal women: A systematic review. Urinary incontinence and other urinary symptoms tend to be frequent at menopause because of hormonal modifications and aging. Urinary symptoms are associated with the genitourinary syndrome of menopause which is characterized by physical chang... |
08/09/2022 | Prevalence of needle-stick injury among nursing students: A systematic review and meta-analysis. | Needle-stick injuries (NSI) are a serious threat to the health of healthcare workers, nurses, and nursing students, as they can expose them to infectious diseases. Different prevalence rates have been reported for this type of injury in different studies worldwide. Therefore, this study aimedto estimate the pooled prev... | ['Meta-Analysis', 'Systematic Review'] | ['Asia', 'Health Personnel', 'Humans', 'Needlestick Injuries', 'Prevalence', 'Students, Nursing'] | 36,045,726 | 0 | Prevalence of needle-stick injury among nursing students: A systematic review and meta-analysis. Needle-stick injuries (NSI) are a serious threat to the health of healthcare workers, nurses, and nursing students, as they can expose them to infectious diseases. Different prevalence rates have been reported for this type... |
15/04/2022 | The preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery: a systematic review and meta-analysis. | To systematically review the literature and provide a comprehensive understanding of the preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery. We searched three electronic databases for randomized controlled trials comparing the results of preoperative pregabalin and p... | ['Meta-Analysis', 'Systematic Review'] | ['Analgesics', 'Analgesics, Opioid', 'Dizziness', 'Humans', 'Lower Extremity', 'Orthopedic Procedures', 'Pain Management', 'Pain, Postoperative', 'Pregabalin'] | 35,418,085 | 0 | The preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery: a systematic review and meta-analysis. To systematically review the literature and provide a comprehensive understanding of the preemptive effects of oral pregabalin on perioperative pain management in lower lim... |
29/09/2020 | Drug-Coated Balloon for De Novo Coronary Artery Lesions: A Systematic Review and Trial Sequential Meta-analysis of Randomized Controlled Trials. | To investigate the efficacy of drug-coated balloon (DCB) treatment for de novo coronary artery lesions in randomized controlled trials (RCTs). DCB was an effective therapy for patients with in-stent restenosis. However, the efficacy of DCB in patients with de novo coronary artery lesions is still unknown. Eligible stud... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Cardiovascular Agents', 'Coated Materials, Biocompatible', 'Coronary Artery Disease', 'Equipment Design', 'Female', 'Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Randomized Controlled Trials as Topic', 'Risk Factors', 'Time Factors', 'Treatment Outcome'... | 32,934,664 | 0 | Drug-Coated Balloon for De Novo Coronary Artery Lesions: A Systematic Review and Trial Sequential Meta-analysis of Randomized Controlled Trials. To investigate the efficacy of drug-coated balloon (DCB) treatment for de novo coronary artery lesions in randomized controlled trials (RCTs). DCB was an effective therapy for... |
05/08/2021 | Reported sources of health inequities in Indigenous Peoples with chronic kidney disease: a systematic review of quantitative studies. | To summarise the evidentiary basis related to causes of inequities in chronic kidney disease among Indigenous Peoples. We conducted a Kaupapa Māori meta-synthesis evaluating the epidemiology of chronic kidney diseases in Indigenous Peoples. Systematic searching of MEDLINE, Google Scholar, OVID Nursing, CENTRAL and Emba... | ['Journal Article', "Research Support, Non-U.S. Gov't", 'Systematic Review'] | ['Humans', 'Canada', 'Cohort Studies', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Health Services, Indigenous', 'Indigenous Peoples', 'Renal Insufficiency, Chronic', 'Health Inequities'] | 34,301,234 | 1 | Reported sources of health inequities in Indigenous Peoples with chronic kidney disease: a systematic review of quantitative studies. To summarise the evidentiary basis related to causes of inequities in chronic kidney disease among Indigenous Peoples. We conducted a Kaupapa Māori meta-synthesis evaluating the epidemio... |
14/02/2024 | Blood Purification for Adult Patients With Severe Infection or Sepsis/Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials. | This study aimed to conduct a comprehensive and updated systematic review with network meta-analysis (NMA) to assess the outcome benefits of various blood purification modalities for adult patients with severe infection or sepsis. We conducted a search of PubMed, MEDLINE, clinical trial registries, Cochrane Library, an... | ['Systematic Review', 'Meta-Analysis', 'Journal Article'] | ['Adult', 'Humans', 'Shock, Septic', 'Network Meta-Analysis', 'Randomized Controlled Trials as Topic', 'Sepsis', 'Polymyxin B', 'Acute Kidney Injury'] | 37,470,680 | 1 | Blood Purification for Adult Patients With Severe Infection or Sepsis/Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials. This study aimed to conduct a comprehensive and updated systematic review with network meta-analysis (NMA) to assess the outcome benefits of various blood purification modalities ... |
08/02/2021 | Retinal Changes in Schizophrenia: A Systematic Review and Meta-analysis Based on Individual Participant Data. | Retinal assessment has indicated the presence of neuronal loss in neurodegenerative disorders, but its role in schizophrenia remains unclear. We sought to synthesize the available evidence considering 3 noninvasive modalities: optical coherence tomography, electroretinography, and fundus photography, and examine their ... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Biomarkers', 'Humans', 'Retina', 'Schizophrenia'] | 31,626,695 | 0 | Retinal Changes in Schizophrenia: A Systematic Review and Meta-analysis Based on Individual Participant Data. Retinal assessment has indicated the presence of neuronal loss in neurodegenerative disorders, but its role in schizophrenia remains unclear. We sought to synthesize the available evidence considering 3 noninva... |
16/12/2022 | Atrial fibrillation after cardiac surgery: A systematic review and meta-analysis. | New-onset postoperative atrial fibrillation (POAF) after cardiac surgery is common, with rates up to 60%. POAF has been associated with early and late stroke, but its association with other cardiovascular outcomes is less known. The objective was to perform a meta-analysis of the studies reporting the association of PO... | ['Meta-Analysis', 'Systematic Review', 'Journal Article', 'Research Support, N.I.H., Extramural', "Research Support, Non-U.S. Gov't"] | ['Humans', 'Atrial Fibrillation', 'Postoperative Complications', 'Cardiac Surgical Procedures', 'Stroke', 'Myocardial Infarction', 'Risk Factors'] | 33,952,399 | 1 | Atrial fibrillation after cardiac surgery: A systematic review and meta-analysis. New-onset postoperative atrial fibrillation (POAF) after cardiac surgery is common, with rates up to 60%. POAF has been associated with early and late stroke, but its association with other cardiovascular outcomes is less known. The objec... |
18/03/2024 | Cold Snare Polypectomy in Small (<10 mm) Pedunculated Colorectal Polyps: A Systematic Review and Meta-analysis. | Endoscopic removal techniques for colorectal polyps include cold snare polypectomy (CSP) and hot snare polypectomy (HSP). Although HSP is recommended for pedunculated polyps (PPs) larger than 10 mm, data regarding use of CSP for PPs <10 mm continues to emerge. We aimed to investigate outcomes of these techniques in sma... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Colonic Polyps', 'Colonoscopy', 'Colon', 'Postoperative Hemorrhage', 'Colorectal Neoplasms'] | 38,289,665 | 0 | Cold Snare Polypectomy in Small (<10 mm) Pedunculated Colorectal Polyps: A Systematic Review and Meta-analysis. Endoscopic removal techniques for colorectal polyps include cold snare polypectomy (CSP) and hot snare polypectomy (HSP). Although HSP is recommended for pedunculated polyps (PPs) larger than 10 mm, data rega... |
14/06/2021 | First-line Treatment of Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: Systematic Review and Network Meta-analysis. | Combination treatments with immuno-oncology (IO) agents and IO agents plus a vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) have been approved for first-line treatment of patients with metastatic renal cell carcinoma (mRCC). No direct comparisons have been performed among these treatm... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Carcinoma, Renal Cell', 'Humans', 'Immune Checkpoint Inhibitors', 'Kidney Neoplasms', 'Prognosis', 'Survival Rate'] | 32,303,427 | 1 | First-line Treatment of Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: Systematic Review and Network Meta-analysis. Combination treatments with immuno-oncology (IO) agents and IO agents plus a vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) have been approved for first-lin... |
14/07/2022 | Nocebo Response in Attention Deficit Hyperactivity Disorder: Meta-Analysis and Meta-Regression of 105 Randomized Clinical Trials. | To determine nocebo response in ADHD, identify covariates modifying nocebo response, and study the relationship between nocebo response and drug safety. Systematic review of randomized, double-blind, placebo-controlled clinical trials (RCT) investigating the efficacy and safety of pharmacological interventions for ADHD... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Attention Deficit Disorder with Hyperactivity', 'Double-Blind Method', 'Humans', 'Nocebo Effect', 'Randomized Controlled Trials as Topic'] | 35,102,771 | 0 | Nocebo Response in Attention Deficit Hyperactivity Disorder: Meta-Analysis and Meta-Regression of 105 Randomized Clinical Trials. To determine nocebo response in ADHD, identify covariates modifying nocebo response, and study the relationship between nocebo response and drug safety. Systematic review of randomized, doub... |
03/04/2023 | Association between hypoalbuminemia and mortality in patients undergoing continuous renal replacement therapy: A systematic review and meta-analysis. | The review aimed to assess if hypoalbuminemia can predict mortality in patients undergoing continuous renal replacement therapy (CRRT). PubMed, Web of Science, Embase, and CENTRAL were searched for relevant articles published up to 24 July 2022. Adjusted data were pooled to calculate the odds ratio (OR). Sensitivity an... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Male', 'Continuous Renal Replacement Therapy', 'Renal Replacement Therapy', 'Hypoalbuminemia', 'Acute Kidney Injury', 'Metabolic Diseases', 'Retrospective Studies'] | 36,996,133 | 1 | Association between hypoalbuminemia and mortality in patients undergoing continuous renal replacement therapy: A systematic review and meta-analysis. The review aimed to assess if hypoalbuminemia can predict mortality in patients undergoing continuous renal replacement therapy (CRRT). PubMed, Web of Science, Embase, an... |
18/05/2021 | A meta-analysis of preclinical studies using antioxidants for the prevention of cisplatin nephrotoxicity: implications for clinical application. | Cisplatin is an effective chemotherapeutic drug whose clinical use and efficacy are limited by its nephrotoxicity, which affects mainly the renal tubules and vasculature. It accumulates in proximal and distal epithelial tubule cells and causes oxidative stress-mediated cell death and malfunction. Consequently, many ant... | ['Journal Article', 'Meta-Analysis', "Research Support, Non-U.S. Gov't", 'Review'] | ['Animals', 'Antioxidants', 'Cisplatin', 'Drug-Related Side Effects and Adverse Reactions', 'Humans', 'Kidney', 'Kidney Tubules'] | 33,170,047 | 1 | A meta-analysis of preclinical studies using antioxidants for the prevention of cisplatin nephrotoxicity: implications for clinical application. Cisplatin is an effective chemotherapeutic drug whose clinical use and efficacy are limited by its nephrotoxicity, which affects mainly the renal tubules and vasculature. It a... |
14/12/2021 | Energy deficiency impairs resistance training gains in lean mass but not strength: A meta-analysis and meta-regression. | Short-term energy deficits impair anabolic hormones and muscle protein synthesis. However, the effects of prolonged energy deficits on resistance training (RT) outcomes remain unexplored. Thus, we conducted a systematic review of PubMed and SportDiscus for randomized controlled trials performing RT in an energy deficit... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Muscle Strength', 'Muscle, Skeletal', 'Resistance Training', 'Weight Loss'] | 34,623,696 | 0 | Energy deficiency impairs resistance training gains in lean mass but not strength: A meta-analysis and meta-regression. Short-term energy deficits impair anabolic hormones and muscle protein synthesis. However, the effects of prolonged energy deficits on resistance training (RT) outcomes remain unexplored. Thus, we con... |
20/03/2024 | The Relationship between Statin Intake and Risk of Pancreatic Cancer: A Systematic Review and Meta-Analysis. | Pancreatic neoplasm is one of the types of cancer with a high incidence and case-fatality rate. This study was designed to investigate the relationship between statin intake and the risk of pancreatic cancer with a systematic review and meta-analysis approach. This study was a systematic review and meta-analysis of stu... | ['Meta-Analysis'] | [] | 38,523,536 | 0 | The Relationship between Statin Intake and Risk of Pancreatic Cancer: A Systematic Review and Meta-Analysis. Pancreatic neoplasm is one of the types of cancer with a high incidence and case-fatality rate. This study was designed to investigate the relationship between statin intake and the risk of pancreatic cancer wit... |
26/01/2024 | Prognostic value of geriatric nutritional risk index in patients with diffuse large B-cell lymphoma: a meta-analysis. | Geriatric nutritional risk index (GNRI) on the prognosis of patients with diffuse large B-cell lymphoma (DLBCL) remains unclear. The purpose of this meta-analysis was to discuss the value of the GNRI in evaluating long-term outcomes in DLBCL. We systematically and roundly retrieved PubMed, Cochrane Library, Embase, Sco... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Humans', 'Lymphoma, Large B-Cell, Diffuse', 'Multicenter Studies as Topic', 'Prognosis', 'Proportional Hazards Models', 'Prospective Studies'] | 37,438,653 | 0 | Prognostic value of geriatric nutritional risk index in patients with diffuse large B-cell lymphoma: a meta-analysis. Geriatric nutritional risk index (GNRI) on the prognosis of patients with diffuse large B-cell lymphoma (DLBCL) remains unclear. The purpose of this meta-analysis was to discuss the value of the GNRI in... |
20/12/2022 | Ablative fractional carbon dioxide laser combined with autologous platelet-rich plasma in the treatment of atrophic acne scars: A systematic review and meta-analysis. | Atrophic acne scars are the most common cutaneous seqaule of acne vulgaris, representing 80%-90% of all acne scars. Ablative fractional carbon dioxide (FCO<sub>2</sub> ) laser is the gold standard treatment for atrophic scars. Additionally, platelet-rich plasma (PRP) is suggested to accelerate the healing process and c... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Cicatrix', 'Lasers, Gas', 'Carbon Dioxide', 'Acne Vulgaris', 'Platelet-Rich Plasma', 'Atrophy', 'Connective Tissue Diseases', 'Treatment Outcome'] | 36,183,145 | 0 | Ablative fractional carbon dioxide laser combined with autologous platelet-rich plasma in the treatment of atrophic acne scars: A systematic review and meta-analysis. Atrophic acne scars are the most common cutaneous seqaule of acne vulgaris, representing 80%-90% of all acne scars. Ablative fractional carbon dioxide (F... |
29/03/2023 | An Updated Systematic Review on the Effects of Aerobic Exercise on Human Blood Lipid Profile. | Sedentary lifestyle and dyslipidemia are well-recognized risk factors for cardiovascular diseases (CVD). Changes in blood lipid profile (total cholesterol (TC), triglycerides, high-density lipoprotein [HDL], and low-density lipoprotein [LDL]) due to the exercise may be beneficial for decreasing CVD-related events. In t... | ['Journal Article', 'Systematic Review'] | ['Humans', 'Male', 'Middle Aged', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Exercise', 'Lipids', 'Triglycerides'] | 35,016,988 | 1 | An Updated Systematic Review on the Effects of Aerobic Exercise on Human Blood Lipid Profile. Sedentary lifestyle and dyslipidemia are well-recognized risk factors for cardiovascular diseases (CVD). Changes in blood lipid profile (total cholesterol (TC), triglycerides, high-density lipoprotein [HDL], and low-density li... |
02/09/2021 | Traditional Chinese medicine for acute coronary syndrome: A meta-analysis of clinical manifestations and objective indicators. | Modern clinical trials and experimental researches of traditional Chinese medicine (TCM) have been conducted for decades and provided support for the prevention and treatment of acute coronary syndrome (ACS). However the level of evidence and the proper application of TCM were still barely satisfactory. In this study, ... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Acute Coronary Syndrome', 'Humans', 'Medicine, Chinese Traditional'] | 34,414,950 | 0 | Traditional Chinese medicine for acute coronary syndrome: A meta-analysis of clinical manifestations and objective indicators. Modern clinical trials and experimental researches of traditional Chinese medicine (TCM) have been conducted for decades and provided support for the prevention and treatment of acute coronary ... |
13/09/2022 | Caffeine intake and the risk of incident kidney stones: a systematic review and meta-analysis. | Kidney stone disease is increasingly common in the general population, with a high recurrence rate after stone removal. It has been proven that caffeine consumption can reduce the risk of diseases, such as stroke and dementia. However, the effect of caffeine intake on the incidence of kidney stones has not been determi... | ['Journal Article', 'Meta-Analysis', 'Review', 'Systematic Review'] | ['Caffeine', 'Cohort Studies', 'Humans', 'Incidence', 'Kidney Calculi', 'Risk Factors', 'Stroke'] | 35,829,948 | 1 | Caffeine intake and the risk of incident kidney stones: a systematic review and meta-analysis. Kidney stone disease is increasingly common in the general population, with a high recurrence rate after stone removal. It has been proven that caffeine consumption can reduce the risk of diseases, such as stroke and dementia... |
19/07/2021 | Network-based gene deletion analysis identifies candidate genes and molecular mechanism involved in clear cell renal cell carcinoma. | Human clear cell renal cell carcinoma (ccRCC) is the most common and frequently occurring histological subtype of RCC. Unlike other carcinomas, candidate predictive biomarkers for this type are in need to explore the molecular mechanism of ccRCC and identify candidate target genes for improving disease management. For ... | ['Journal Article', 'Meta-Analysis'] | ['Biomarkers, Tumor', 'Carcinoma, Renal Cell', 'Case-Control Studies', 'Gene Deletion', 'Humans', 'Kidney Neoplasms', 'Protein Interaction Maps'] | 33,707,362 | 1 | Network-based gene deletion analysis identifies candidate genes and molecular mechanism involved in clear cell renal cell carcinoma. Human clear cell renal cell carcinoma (ccRCC) is the most common and frequently occurring histological subtype of RCC. Unlike other carcinomas, candidate predictive biomarkers for this ty... |
26/07/2022 | Serum Adiponectin Level in Different Stages of Type 2 Diabetic Kidney Disease: A Meta-Analysis. | Biomarkers in predicting the stages of nephropathy associated with type 2 diabetes mellitus are urgent, and adiponectin may be a promising biomarker. This meta-analysis examined the association of serum adiponectin level with the stages of type 2 diabetic nephropathy. Databases including PubMed, Cochrane Library, EMBAS... | ['Journal Article', 'Meta-Analysis', 'Retracted Publication'] | ['Adiponectin', 'Albuminuria', 'Biomarkers', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Humans'] | 35,872,926 | 1 | Serum Adiponectin Level in Different Stages of Type 2 Diabetic Kidney Disease: A Meta-Analysis. Biomarkers in predicting the stages of nephropathy associated with type 2 diabetes mellitus are urgent, and adiponectin may be a promising biomarker. This meta-analysis examined the association of serum adiponectin level wit... |
10/03/2022 | Impact of AKI care bundles on kidney and patient outcomes in hospitalized patients: a systematic review and meta-analysis. | A bundle of preventive measures can be taken to avoid acute kidney injury (AKI) or progression of AKI. We performed a systematic review and meta-analysis to evaluate the compliance to AKI care bundles in hospitalized patients and its impact on kidney and patient outcomes. Randomized controlled trials, observational and... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Acute Kidney Injury', 'Hospitalization', 'Humans', 'Kidney', 'Patient Care Bundles', 'Treatment Outcome'] | 34,625,046 | 1 | Impact of AKI care bundles on kidney and patient outcomes in hospitalized patients: a systematic review and meta-analysis. A bundle of preventive measures can be taken to avoid acute kidney injury (AKI) or progression of AKI. We performed a systematic review and meta-analysis to evaluate the compliance to AKI care bund... |
15/03/2024 | Concurrent neoadjuvant endocrine therapy with chemotherapy in HR+HER2- breast cancer: a systematic review and meta-analysis. | The role of simultaneous neoadjuvant endocrine therapy in chemotherapy in HR+HER2- breast cancer continues to be controversial. This systematic review and meta-analysis was conducted to further evaluate the effectiveness and safety of this strategy for HR+HER2- breast cancer patients. Trials in which HR+HER2- breast ca... | ['Meta-Analysis', 'Systematic Review'] | ['Humans', 'Female', 'Breast Neoplasms', 'Neoadjuvant Therapy', 'Tamoxifen', 'Combined Modality Therapy', 'Aromatase Inhibitors', 'Randomized Controlled Trials as Topic'] | 38,481,446 | 0 | Concurrent neoadjuvant endocrine therapy with chemotherapy in HR+HER2- breast cancer: a systematic review and meta-analysis. The role of simultaneous neoadjuvant endocrine therapy in chemotherapy in HR+HER2- breast cancer continues to be controversial. This systematic review and meta-analysis was conducted to further e... |
27/04/2020 | Autosomal Dominant Polycystic Kidney Disease Is a Risk Factor for Posttransplantation Diabetes Mellitus: An Updated Systematic Review and Meta-analysis. | Autosomal dominant polycystic kidney disease (ADPKD) is linked with risk for posttransplantation diabetes mellitus (PTDM), but this association has methodologic limitations like diagnostic criteria. The aim of this study was to use contemporary diagnostic criteria for PTDM and explore any risk association for kidney tr... | ['Journal Article'] | [] | 32,548,247 | 1 | Autosomal Dominant Polycystic Kidney Disease Is a Risk Factor for Posttransplantation Diabetes Mellitus: An Updated Systematic Review and Meta-analysis. Autosomal dominant polycystic kidney disease (ADPKD) is linked with risk for posttransplantation diabetes mellitus (PTDM), but this association has methodologic limita... |
05/10/2023 | Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis. | Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. To evaluate associations of lower eGFR based on creatinine alone, lower eGFR based on creatinine combined with cystatin C, and more severe albuminuria with adverse kidney outcomes, card... | ['Journal Article', 'Meta-Analysis', 'Research Support, N.I.H., Extramural'] | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Albuminuria', 'Atrial Fibrillation', 'Creatinine', 'Cystatin C', 'Glomerular Filtration Rate', 'Retrospective Studies', 'Renal Insufficiency, Chronic', 'Aged', 'Albumins', 'Disease Progression', 'Internationality', 'Comorbidity'] | 37,787,795 | 1 | Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis. Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. To evaluate associations of lower eGFR based on creatinine alone, ... |
21/05/2024 | Effectiveness of teach-back for chronic kidney disease patient education: A systematic review. | Education is an essential component in optimising chronic disease self-management. Teach-back is a robust approach in patient education, which is suitable for varying health literacy although its effectiveness in chronic kidney disease patient education is unknown. To evaluate the impact of teach-back method in health ... | ['Systematic Review', 'Journal Article', 'Review'] | ['Humans', 'Renal Insufficiency, Chronic', 'Patient Education as Topic', 'Teach-Back Communication', 'Health Literacy', 'Self-Management'] | 37,010,245 | 1 | Effectiveness of teach-back for chronic kidney disease patient education: A systematic review. Education is an essential component in optimising chronic disease self-management. Teach-back is a robust approach in patient education, which is suitable for varying health literacy although its effectiveness in chronic kidn... |
06/10/2021 | Whey protein supplementation and its potentially adverse effects on health: a systematic review. | Whey protein comprises soluble whey proteins and its benefits are well described in the literature. However, there are not many studies investigating the potential adverse effect of a diet with indiscriminate use of this supplement. The aim of this study was to perform a systematic review of papers that addressed this ... | ['Journal Article', 'Systematic Review'] | ['Diet', 'Dietary Supplements', 'Gastrointestinal Microbiome', 'Health Status', 'Humans', 'Kidney Diseases', 'Liver Diseases', 'Whey Proteins'] | 32,702,243 | 1 | Whey protein supplementation and its potentially adverse effects on health: a systematic review. Whey protein comprises soluble whey proteins and its benefits are well described in the literature. However, there are not many studies investigating the potential adverse effect of a diet with indiscriminate use of this su... |
14/03/2023 | Effects of the Sodium-Glucose Cotransporter Inhibitors on Cardiovascular Death and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Clinical Trials. | Patients with diabetes mellitus are at an increased risk of cardiovascular morbidity and all-cause mortality. Heart failure and type 2 diabetes often occur concomitantly, and each disease independently increases the risk for the other. Emerging data have revealed that some sodium-glucose cotransporter inhibitors (SGLTi... | ['Meta-Analysis', 'Systematic Review'] | ['Humans', 'Diabetes Mellitus, Type 2', 'Cardiovascular Diseases', 'Heart Failure', 'Myocardial Infarction', 'Stroke', 'Glucose', 'Sodium'] | 36,572,841 | 0 | Effects of the Sodium-Glucose Cotransporter Inhibitors on Cardiovascular Death and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Clinical Trials. Patients with diabetes mellitus are at an increased risk of cardiovascular morbidity and all-cause mortality. Heart failure and ... |
05/04/2024 | Thrombopoietin levels in sepsis and septic shock - a systematic review and meta-analysis. | Sepsis is a life-threatening condition implicating an inadequate activation of the immune system. Platelets act as modulators and contributors to immune processes. Indeed, altered platelet turnover, thrombotic events, and changes in thrombopoietin levels in systemic inflammation have been reported, but thrombopoietin-l... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Adult', 'Humans', 'Shock, Septic', 'Thrombopoietin', 'Sepsis'] | 38,037,809 | 0 | Thrombopoietin levels in sepsis and septic shock - a systematic review and meta-analysis. Sepsis is a life-threatening condition implicating an inadequate activation of the immune system. Platelets act as modulators and contributors to immune processes. Indeed, altered platelet turnover, thrombotic events, and changes ... |
14/05/2021 | Comparable outcomes in mini-midvastus versus mini-medial parapatellar approach in total knee arthroplasty: a meta-analysis and systematic review. | Minimally invasive surgery (MIS) techniques in total knee arthroplasties (TKA) have gained popularity over conventional techniques due to benefits of hastened recovery and reduced complications. There are a variety of MIS techniques available and two most common techniques currently employed are the mini-midvastus (mMV... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Arthroplasty, Replacement, Knee', 'Humans', 'Knee Joint', 'Minimally Invasive Surgical Procedures', 'Operative Time', 'Range of Motion, Articular', 'Treatment Outcome'] | 32,062,865 | 0 | Comparable outcomes in mini-midvastus versus mini-medial parapatellar approach in total knee arthroplasty: a meta-analysis and systematic review. Minimally invasive surgery (MIS) techniques in total knee arthroplasties (TKA) have gained popularity over conventional techniques due to benefits of hastened recovery and re... |
13/05/2020 | Hormone replacement therapy after surgery for epithelial ovarian cancer. | Women who have undergone surgical treatment for epithelial ovarian cancer (EOC) may develop menopausal symptoms due to immediate loss of ovarian function following surgery and chemotherapy. Women may experience vasomotor symptoms, sleep disturbance, difficulty concentrating, sexual dysfunction, vaginal symptoms and acc... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Carcinoma, Ovarian Epithelial', 'Female', 'Hormone Replacement Therapy', 'Humans', 'Menopause, Premature', 'Ovarian Neoplasms', 'Quality of Life', 'Randomized Controlled Trials as Topic'] | 31,989,588 | 0 | Hormone replacement therapy after surgery for epithelial ovarian cancer. Women who have undergone surgical treatment for epithelial ovarian cancer (EOC) may develop menopausal symptoms due to immediate loss of ovarian function following surgery and chemotherapy. Women may experience vasomotor symptoms, sleep disturbanc... |
14/04/2022 | The efficacy and safety of roxadustat for the treatment of anemia in non-dialysis dependent chronic kidney disease patients: An updated systematic review and meta-analysis of randomized clinical trials. | Roxadustat (ROX) is a new medication for anemia as a complication of chronic kidney disease (CKD). Our meta-analysis aims to evaluate the efficacy and safety of ROX, especially on the cardiovascular risks, for anemia in NDD-CKD patients. Electronic databases were searched systematically from inception to July 2021 to l... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Anemia', 'Ferritins', 'Glycine', 'Hepcidins', 'Humans', 'Iron', 'Isoquinolines', 'Randomized Controlled Trials as Topic', 'Renal Insufficiency, Chronic', 'Transferrin'] | 35,363,823 | 1 | The efficacy and safety of roxadustat for the treatment of anemia in non-dialysis dependent chronic kidney disease patients: An updated systematic review and meta-analysis of randomized clinical trials. Roxadustat (ROX) is a new medication for anemia as a complication of chronic kidney disease (CKD). Our meta-analysis ... |
07/05/2020 | Asthma control in the quality of life levels of asthmatic patients' caregivers: a systematic review with meta-analysis and meta-regression. | To perform a systematic review with meta-analysis and meta-regression to correlate the total scores of asthma control with the increase in the total scores of health-related quality of life levels of parents of asthmatic children. The search was carried out in the following databases: PubMed (MEDLINE); Embase and Scien... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Adolescent', 'Asthma', 'Caregivers', 'Child', 'Humans', 'Parents', 'Quality of Life', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 30,540,924 | 0 | Asthma control in the quality of life levels of asthmatic patients' caregivers: a systematic review with meta-analysis and meta-regression. To perform a systematic review with meta-analysis and meta-regression to correlate the total scores of asthma control with the increase in the total scores of health-related qualit... |
01/12/2022 | Systematic review and meta-analysis: Artificial intelligence for the diagnosis of gastric precancerous lesions and Helicobacter pylori infection. | The endoscopic diagnosis of Helicobacter-pylori(H.pylori) infection and gastric precancerous lesions(GPL), namely atrophic-gastritis and intestinal-metaplasia, still remains challenging. Artificial intelligence(AI) may represent a powerful resource for the endoscopic recognition of these conditions. To explore the diag... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Artificial Intelligence', 'Helicobacter Infections', 'Helicobacter pylori', 'Precancerous Conditions', 'Prospective Studies', 'Stomach Neoplasms'] | 35,382,973 | 0 | Systematic review and meta-analysis: Artificial intelligence for the diagnosis of gastric precancerous lesions and Helicobacter pylori infection. The endoscopic diagnosis of Helicobacter-pylori(H.pylori) infection and gastric precancerous lesions(GPL), namely atrophic-gastritis and intestinal-metaplasia, still remains ... |
17/09/2020 | [Meta-analysis on effectiveness and safety of Pudilan Xiaoyan Oral Liquid on child upper respiratory infection]. | To systematically review the effectiveness and safety of Pudilan Xiaoyan Oral Liquid on child upper respiratory infection and conduct Meta-analysis. We electronically retrieved databases, including PubMed, Web of Science, VIP, WanFang and CNKI, for published articles of randomized controlled trials(RCTs) of Pudilan Xia... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Child', 'Drugs, Chinese Herbal', 'Humans', 'Pharyngitis', 'Tumor Necrosis Factor-alpha'] | 32,495,572 | 0 | [Meta-analysis on effectiveness and safety of Pudilan Xiaoyan Oral Liquid on child upper respiratory infection]. To systematically review the effectiveness and safety of Pudilan Xiaoyan Oral Liquid on child upper respiratory infection and conduct Meta-analysis. We electronically retrieved databases, including PubMed, W... |
18/02/2021 | Comorbidities in SARS-CoV-2 Patients: a Systematic Review and Meta-Analysis. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the globe at unprecedented speed and is showing no signs of slowing down. The outbreak of coronavirus disease 2019 (COVID-19) has led to significant health burden in infected patients especially in those with underlying comorbidities... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['COVID-19', 'Comorbidity', 'Hospitalization', 'Humans', 'Prevalence', 'Risk Factors', 'SARS-CoV-2', 'Treatment Outcome'] | 33,563,817 | 1 | Comorbidities in SARS-CoV-2 Patients: a Systematic Review and Meta-Analysis. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the globe at unprecedented speed and is showing no signs of slowing down. The outbreak of coronavirus disease 2019 (COVID-19) has led to significant health ... |
15/03/2021 | A meta-analysis of mortality after minor amputation among patients with diabetes and/or peripheral vascular disease. | Foot complications in patients with diabetes or peripheral artery disease (PAD) are serious events in the life of these patients that often lead to amputations and mortality. No evidence synthesis has been reported on the mortality rates after minor lower extremity amputation; thus, a quantitative evidence synthesis wa... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Amputation, Surgical', 'Diabetic Foot', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peripheral Vascular Diseases', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Treatment Outcome'] | 32,835,790 | 1 | A meta-analysis of mortality after minor amputation among patients with diabetes and/or peripheral vascular disease. Foot complications in patients with diabetes or peripheral artery disease (PAD) are serious events in the life of these patients that often lead to amputations and mortality. No evidence synthesis has be... |
06/04/2021 | Risk factors for all-cause hospital readmission following exacerbation of COPD: a systematic review and meta-analysis. | Readmission rates following hospitalisation for COPD exacerbations are unacceptably high, and the contributing factors are poorly understood. Our objective was to summarise and evaluate the factors associated with 30- and 90-day all-cause readmission following hospitalisation for an exacerbation of COPD. We systematica... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Adult', 'Aged', 'Aged, 80 and over', 'Comorbidity', 'Disease Progression', 'Female', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Patient Readmission', 'Prognosis', 'Pulmonary Disease, Chronic Obstructive', 'Risk Assessment', 'Risk Factors', 'Time Factors'] | 32,499,306 | 1 | Risk factors for all-cause hospital readmission following exacerbation of COPD: a systematic review and meta-analysis. Readmission rates following hospitalisation for COPD exacerbations are unacceptably high, and the contributing factors are poorly understood. Our objective was to summarise and evaluate the factors ass... |
22/11/2022 | Efficacy and safety of platelet-rich plasma combined with hyaluronic acid versus platelet-rich plasma alone for knee osteoarthritis: a systematic review and meta-analysis. | To systematically evaluate the curative efficacy and safety of platelet-rich plasma (PRP) combined with hyaluronic acid (HA) in the treatment of knee osteoarthritis (KOA), comparing with platelet-rich plasma alone. Cochrane Library, PubMed, China National Knowledge Infrastructure (CNKI) and Embase were searched for ran... | ['Meta-Analysis', 'Systematic Review'] | ['Humans', 'Hyaluronic Acid', 'Osteoarthritis, Knee', 'Injections, Intra-Articular', 'Platelet-Rich Plasma', 'Minimal Clinically Important Difference'] | 36,403,041 | 0 | Efficacy and safety of platelet-rich plasma combined with hyaluronic acid versus platelet-rich plasma alone for knee osteoarthritis: a systematic review and meta-analysis. To systematically evaluate the curative efficacy and safety of platelet-rich plasma (PRP) combined with hyaluronic acid (HA) in the treatment of kne... |
13/04/2020 | Endovascular coiling versus surgical clipping for the treatment of unruptured cerebral aneurysms: Direct comparison of procedure-related complications. | Endovascular coiling and surgical clipping are routinely used to treat unruptured cerebral aneurysms (UCAs). However, the evidence to support the efficacy of these approaches is limited. We aimed to analyze the efficacy of endovascular coiling compared with surgical clipping in patients with UCAs. A systematic search o... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Endovascular Procedures', 'Hospital Mortality', 'Humans', 'Intracranial Aneurysm', 'Length of Stay', 'Neurosurgical Procedures', 'Postoperative Complications', 'Reoperation'] | 32,221,092 | 0 | Endovascular coiling versus surgical clipping for the treatment of unruptured cerebral aneurysms: Direct comparison of procedure-related complications. Endovascular coiling and surgical clipping are routinely used to treat unruptured cerebral aneurysms (UCAs). However, the evidence to support the efficacy of these appr... |
10/02/2023 | Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review. | A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with utility as biomarkers and therapeutic targets. We aimed to identify and assess all ... | ['Journal Article', 'Review'] | [] | 36,831,050 | 1 | Epigenetic Mechanisms and Nephrotic Syndrome: A Systematic Review. A small subset of people with nephrotic syndrome (NS) have genetically driven disease. However, the disease mechanisms for the remaining majority are unknown. Epigenetic marks are reversible but stable regulators of gene expression with utility as bioma... |
19/04/2024 | Colchicine for the treatment of patients with COVID-19: an updated systematic review and meta-analysis of randomised controlled trials. | We conducted an updated systematic review and meta-analysis to investigate the effect of colchicine treatment on clinical outcomes in patients with COVID-19. Systematic review and meta-analysis. We searched PubMed, Embase, the Cochrane Library, medRxiv and ClinicalTrials.gov from inception to January 2023. All randomis... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'COVID-19', 'Colchicine', 'Hospitalization', 'Respiration, Artificial', 'Randomized Controlled Trials as Topic'] | 38,631,824 | 0 | Colchicine for the treatment of patients with COVID-19: an updated systematic review and meta-analysis of randomised controlled trials. We conducted an updated systematic review and meta-analysis to investigate the effect of colchicine treatment on clinical outcomes in patients with COVID-19. Systematic review and meta... |
23/10/2020 | Effect of fenugreek consumption on serum lipid profile: A systematic review and meta-analysis. | Various studies have shown that Trigonella foenum-graecum (fenugreek) supplementation has lipid-lowering activity. This meta-analysis was performed to evaluate the effect of fenugreek supplementation on human serum lipid profile. Data sources were PubMed, EMBASE, Scopus, and Coherence library which were searched system... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Diabetes Mellitus', 'Female', 'Humans', 'Lipid Metabolism', 'Lipids', 'Male', 'Middle Aged', 'Phytotherapy', 'Plant Extracts', 'Randomized Controlled Trials as Topic', 'Triglycerides', 'Trigonella', 'Young Adult'] | 32,385,866 | 0 | Effect of fenugreek consumption on serum lipid profile: A systematic review and meta-analysis. Various studies have shown that Trigonella foenum-graecum (fenugreek) supplementation has lipid-lowering activity. This meta-analysis was performed to evaluate the effect of fenugreek supplementation on human serum lipid prof... |
21/06/2021 | Impact of obstructive sleep apnea on silent cerebral small vessel disease: a systematic review and meta-analysis. | Cerebral small vessel disease (CSVD) is a well-known cause of vascular dementia, a leading medical morbidity in the aging population. Obstructive sleep apnea (OSA) has been validated as a cardiovascular risk factor. However, the relationship between these two clinical syndromes is not well established. We aimed to asse... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Cerebral Small Vessel Diseases', 'Humans', 'Magnetic Resonance Imaging', 'Neuroimaging', 'Sleep Apnea, Obstructive', 'Stroke, Lacunar'] | 32,028,230 | 0 | Impact of obstructive sleep apnea on silent cerebral small vessel disease: a systematic review and meta-analysis. Cerebral small vessel disease (CSVD) is a well-known cause of vascular dementia, a leading medical morbidity in the aging population. Obstructive sleep apnea (OSA) has been validated as a cardiovascular ris... |
31/01/2022 | Sex differences in chronic kidney disease prevalence in Asia: a systematic review and meta-analysis. | Previous reports on the prevalence of chronic kidney disease (CKD) in Asia have suggested important sex disparities but have been inconsistent in nature. We sought to synthesize available sex-disaggregated CKD prevalence data in Asia to quantify sex disparities in the region. We systematically searched MEDLINE and Emba... | ['Journal Article'] | [] | 35,664,281 | 1 | Sex differences in chronic kidney disease prevalence in Asia: a systematic review and meta-analysis. Previous reports on the prevalence of chronic kidney disease (CKD) in Asia have suggested important sex disparities but have been inconsistent in nature. We sought to synthesize available sex-disaggregated CKD prevalenc... |
24/05/2021 | Frailty and Physical Fitness in Elderly People: A Systematic Review and Meta-analysis. | Frailty is an age-related condition that implies a vulnerability status affecting quality of life and independence of the elderly. Physical fitness is closely related to frailty, as some of its components are used for the detection of this condition. This systematic review and meta-analysis was conducted to investigate... | ['Meta-Analysis', 'Systematic Review'] | ['Aged', 'Cross-Sectional Studies', 'Frail Elderly', 'Frailty', 'Geriatric Assessment', 'Humans', 'Middle Aged', 'Physical Fitness', 'Quality of Life'] | 33,201,455 | 0 | Frailty and Physical Fitness in Elderly People: A Systematic Review and Meta-analysis. Frailty is an age-related condition that implies a vulnerability status affecting quality of life and independence of the elderly. Physical fitness is closely related to frailty, as some of its components are used for the detection o... |
19/04/2022 | Ovarian cancer risk in relation to blood lipid levels and hyperlipidemia: a systematic review and meta-analysis of observational epidemiologic studies. | Epidemiologic evidence regarding association of ovarian cancer risk with blood lipid level and hyperlipidemia is inconsistent. We aimed to synthesize available epidemiologic studies to disentangle associations of cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholester... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Epidemiologic Studies', 'Female', 'Humans', 'Hyperlipidemias', 'Lipids', 'Ovarian Neoplasms', 'Triglycerides'] | 32,483,012 | 0 | Ovarian cancer risk in relation to blood lipid levels and hyperlipidemia: a systematic review and meta-analysis of observational epidemiologic studies. Epidemiologic evidence regarding association of ovarian cancer risk with blood lipid level and hyperlipidemia is inconsistent. We aimed to synthesize available epidemio... |
11/02/2020 | Role of immune checkpoint inhibitor-based therapies for metastatic renal cell carcinoma in the first-line setting: A Bayesian network analysis. | Several novel immune checkpoint inhibitor (ICI)-based treatments exhibited promising survival benefits for metastatic renal cell carcinoma (mRCC), yet there is no current guidance regarding the optimum first-line regimen. We performed this network analysis to compare the efficacy and safety of all available treatments ... | ['Journal Article', 'Meta-Analysis'] | ['Animals', 'Antineoplastic Agents, Immunological', 'Bayes Theorem', 'Biomarkers, Tumor', 'Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Disease Models, Animal', 'Disease Progression', 'Female', 'Humans', 'Immunomodulation', 'Kidney Neoplasms', 'Male', 'Mice', 'Proportional Hazards Models', 'Xenograft Model Antitumor As... | 31,439,476 | 1 | Role of immune checkpoint inhibitor-based therapies for metastatic renal cell carcinoma in the first-line setting: A Bayesian network analysis. Several novel immune checkpoint inhibitor (ICI)-based treatments exhibited promising survival benefits for metastatic renal cell carcinoma (mRCC), yet there is no current guida... |
19/06/2020 | Association of obesity with bone mineral density and osteoporosis in adults: a systematic review and meta-analysis. | Results from previous studies investigating the association of obesity with bone mineral density (BMD) and osteoporosis (OP) are inconsistent. The purpose of the present study was to examine whether obesity is associated with BMD and the risk of OP. This is a meta-analysis. A computerised literature search was conducte... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Adult', 'Bone Density', 'Humans', 'Obesity', 'Osteoporosis'] | 31,837,611 | 0 | Association of obesity with bone mineral density and osteoporosis in adults: a systematic review and meta-analysis. Results from previous studies investigating the association of obesity with bone mineral density (BMD) and osteoporosis (OP) are inconsistent. The purpose of the present study was to examine whether obesi... |
14/08/2023 | Melatonin intervention to prevent delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials. | To determine the preventive effect of melatonin on delirium in the intensive care units. We conducted a systematic search of the PubMed, Cochrane Library, Science, Embase, and CNKI databases, with retrieval dates ranging from the databases' inception to September 2022. Controlled trials on melatonin and placebo for pre... | ['Meta-Analysis', 'Systematic Review', "Research Support, Non-U.S. Gov't"] | ['Humans', 'Melatonin', 'Delirium', 'Randomized Controlled Trials as Topic', 'Intensive Care Units', 'Length of Stay'] | 37,564,987 | 0 | Melatonin intervention to prevent delirium in the intensive care units: a systematic review and meta-analysis of randomized controlled trials. To determine the preventive effect of melatonin on delirium in the intensive care units. We conducted a systematic search of the PubMed, Cochrane Library, Science, Embase, and C... |
29/04/2021 | Sarcopenia as a predictor of postoperative outcomes after urologic oncology surgery: A systematic review and meta-analysis. | Sarcopenia as a reliable prognostic predictor in urologic oncology surgery remains controversial, and no consensus amongst researchers exists regarding the management of patients with sarcopenia. This meta-analysis was conducted to investigate the association between sarcopenia and postoperative outcomes after urologic... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Postoperative Complications', 'Prognosis', 'Sarcopenia', 'Survival Rate', 'Treatment Outcome', 'Urologic Neoplasms', 'Urologic Surgical Procedures'] | 32,268,990 | 0 | Sarcopenia as a predictor of postoperative outcomes after urologic oncology surgery: A systematic review and meta-analysis. Sarcopenia as a reliable prognostic predictor in urologic oncology surgery remains controversial, and no consensus amongst researchers exists regarding the management of patients with sarcopenia. ... |
10/02/2021 | Risk factors associated with penile prosthesis infection: systematic review and meta-analysis. | The aim of this study was to identify the factors associated with infection in patients who undergo penile prosthesis implantation. We performed a systematic review/meta-analysis, including clinical trials, quasi-experiments, retrospective and prospective cohort studies, and case-control studies. Searching was done in ... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Erectile Dysfunction', 'Humans', 'Male', 'Penile Implantation', 'Penile Prosthesis', 'Prospective Studies', 'Retrospective Studies', 'Risk Factors'] | 32,015,525 | 0 | Risk factors associated with penile prosthesis infection: systematic review and meta-analysis. The aim of this study was to identify the factors associated with infection in patients who undergo penile prosthesis implantation. We performed a systematic review/meta-analysis, including clinical trials, quasi-experiments,... |
22/03/2022 | Comparative effectiveness of cardiovascular, renal and safety outcomes of second-line antidiabetic drugs use in people with type 2 diabetes: A systematic review and network meta-analysis of randomised controlled trials. | To compare the cardiovascular, renal and safety outcomes of second-line glucose-lowering agents used in the management of people with type 2 diabetes. MEDLINE, EMBASE and CENTRAL were searched from inception to 13 July 2021 for randomised controlled trials comparing second-line glucose lowering therapies with placebo, ... | ['Comparative Study', 'Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Glucagon-Like Peptide-1 Receptor', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Kidney Diseases', 'Metformin', 'Network Meta-Analysis', 'Pancreatitis', 'Randomized Controlled Trials as Topic', 'Sodium-Glucose Transporter 2 Inhibitors', 'Sulfonylurea Compounds', ... | 34,962,662 | 1 | Comparative effectiveness of cardiovascular, renal and safety outcomes of second-line antidiabetic drugs use in people with type 2 diabetes: A systematic review and network meta-analysis of randomised controlled trials. To compare the cardiovascular, renal and safety outcomes of second-line glucose-lowering agents used... |
25/06/2021 | Cemented versus uncemented hemiarthroplasty for the management of femoral neck fractures in the elderly: a meta-analysis and systematic review. | Hemiarthroplasty is commonly used to treat unstable femoral neck fractures in older patients. However, there is no consensus on the use of cement during hemiarthroplasty. Therefore, we performed a systematic review to focus on the outcomes of cemented and uncemented hemiarthroplasty for the treatment of femoral neck fr... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Bone Cements', 'Female', 'Femoral Neck Fractures', 'Femur', 'Hemiarthroplasty', 'Humans', 'Male', 'Postoperative Complications', 'Randomized Controlled Trials as Topic', 'Treatment Outcome'] | 33,423,078 | 0 | Cemented versus uncemented hemiarthroplasty for the management of femoral neck fractures in the elderly: a meta-analysis and systematic review. Hemiarthroplasty is commonly used to treat unstable femoral neck fractures in older patients. However, there is no consensus on the use of cement during hemiarthroplasty. There... |
16/12/2023 | Success rate and safety of living donor kidney transplantation in ABO blood group incompatible relatives: A systematic review and meta-analysis. | Kidney transplantation is considered an ideal treatment for end-stage renal disease (ESRD) because it provides a longer and better quality of life than dialysis. ABO-incompatible (ABO-I) kidney transplantation relies on two principles: (i) removal of antibodies from a blood group; and (ii) inhibition of reappearance of... | ['Meta-Analysis', 'Systematic Review', 'Journal Article', 'Review'] | ['Humans', 'Kidney Transplantation', 'ABO Blood-Group System', 'Living Donors', 'Quality of Life', 'Renal Dialysis', 'Blood Group Incompatibility', 'Antibodies', 'Graft Survival', 'Graft Rejection'] | 37,648,033 | 1 | Success rate and safety of living donor kidney transplantation in ABO blood group incompatible relatives: A systematic review and meta-analysis. Kidney transplantation is considered an ideal treatment for end-stage renal disease (ESRD) because it provides a longer and better quality of life than dialysis. ABO-incompati... |
01/06/2020 | Effects of kinesio taping alone versus sham taping in individuals with musculoskeletal conditions after intervention for at least one week: a systematic review and meta-analysis. | Kinesiotaping (KT), has emerged as an interesting and relatively novel method for treating musculoskeletal conditions. To date, none of the systematic reviews with meta-analysis have addressed the efficacy of KT alone (without any other intervention) over sham taping (ST). The present meta-analysis aimed to investigate... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Athletic Tape', 'Disability Evaluation', 'Humans', 'Low Back Pain', 'Musculoskeletal Pain', 'Osteoarthritis, Knee', 'Pain Measurement', 'Randomized Controlled Trials as Topic'] | 31,076,093 | 0 | Effects of kinesio taping alone versus sham taping in individuals with musculoskeletal conditions after intervention for at least one week: a systematic review and meta-analysis. Kinesiotaping (KT), has emerged as an interesting and relatively novel method for treating musculoskeletal conditions. To date, none of the s... |
17/07/2019 | A comparison of the prognosis of papillary and clear cell renal cell carcinoma: Evidence from a meta-analysis. | To compare the prognosis of papillary and clear cell renal cell carcinoma (RCC) in order to determine the optimal follow-up and therapy for patients with RCC. A systematic search of Web of Science, EMBASE, Cochrane Library, and PubMed databases was conducted for articles published through July 30, 2018, reporting on a ... | ['Comparative Study', 'Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Carcinoma, Renal Cell', 'Humans', 'Kidney Neoplasms', 'Prognosis'] | 31,277,173 | 1 | A comparison of the prognosis of papillary and clear cell renal cell carcinoma: Evidence from a meta-analysis. To compare the prognosis of papillary and clear cell renal cell carcinoma (RCC) in order to determine the optimal follow-up and therapy for patients with RCC. A systematic search of Web of Science, EMBASE, Coc... |
13/10/2021 | Spontaneous Bladder Rupture after Normal Vaginal Delivery: Description of a Rare Complication and Systematic Review of the Literature. | To identify the possible causes of spontaneous bladder rupture after normal vaginal delivery and to propose a diagnostic and therapeutic algorithm. MEDLINE (PubMed), Web of Science and Scopus databases were searched up to August 2020. Manuscripts considered were published from 1990 and only English articles were includ... | ['Journal Article', 'Review'] | [] | 34,679,583 | 1 | Spontaneous Bladder Rupture after Normal Vaginal Delivery: Description of a Rare Complication and Systematic Review of the Literature. To identify the possible causes of spontaneous bladder rupture after normal vaginal delivery and to propose a diagnostic and therapeutic algorithm. MEDLINE (PubMed), Web of Science and ... |
27/11/2019 | Prophylactic atorvastatin prior to intra-arterial administration of iodinated contrast media for prevention of contrast-induced acute kidney injury: A meta-analysis of randomized trial data
. | The efficacy of high-dose atorvastatin pretreatment in reducing the incidence of contrast-induced nephropathy in patients undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI) has been examined in some randomized studies. However, the results across the trials remain controversial. This stud... | ['Journal Article', 'Meta-Analysis'] | ['Acute Kidney Injury', 'Atorvastatin', 'Contrast Media', 'Coronary Angiography', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Incidence', 'Percutaneous Coronary Intervention'] | 31,347,493 | 1 | Prophylactic atorvastatin prior to intra-arterial administration of iodinated contrast media for prevention of contrast-induced acute kidney injury: A meta-analysis of randomized trial data
. The efficacy of high-dose atorvastatin pretreatment in reducing the incidence of contrast-induced nephropathy in patients underg... |
27/03/2023 | Effectiveness of healthcare workers and volunteers training on improving tuberculosis case detection: A systematic review and meta-analysis. | Tuberculosis is the second most common infectious cause of death globally. Low TB case detection remains a major challenge to achieve the global End TB targets. This systematic review and meta-analysis aimed to determine whether training of health professionals and volunteers increase TB case detection. We performed a ... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Tuberculosis', 'Tuberculosis, Pulmonary', 'Health Personnel'] | 36,952,429 | 0 | Effectiveness of healthcare workers and volunteers training on improving tuberculosis case detection: A systematic review and meta-analysis. Tuberculosis is the second most common infectious cause of death globally. Low TB case detection remains a major challenge to achieve the global End TB targets. This systematic re... |
05/02/2021 | Indocyanine Green Fluorescence Versus Blue Dye or Radioisotope Regarding Detection Rate of Sentinel Lymph Node Biopsy and Nodes Removed in Breast Cancer: A Systematic Review and Meta-Analysis. | Either blue dye (BD) or radioisotope (RI) is mainly used for sentinel lymph node biopsy (SLNB) in breast cancer patients. Unlike the BD, RI has lower false-negative rate of SLNB. However, its lymphoscintigraphy, difficulty in preoperative injection, and undetected sentinel lymph nodes in some cases cause surgeons to re... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Breast Neoplasms', 'Coloring Agents', 'Female', 'Fluorescence', 'Humans', 'Indocyanine Green', 'Methylene Blue', 'Prognosis', 'Radiopharmaceuticals', 'Sentinel Lymph Node'] | 32,458,621 | 0 | Indocyanine Green Fluorescence Versus Blue Dye or Radioisotope Regarding Detection Rate of Sentinel Lymph Node Biopsy and Nodes Removed in Breast Cancer: A Systematic Review and Meta-Analysis. Either blue dye (BD) or radioisotope (RI) is mainly used for sentinel lymph node biopsy (SLNB) in breast cancer patients. Unlik... |
01/09/2021 | SGLT2 inhibitors for prevention of cardiorenal events in people with type 2 diabetes without cardiorenal disease: A meta-analysis of large randomized trials and cohort studies. | To investigate whether sodium glucose cotransporter 2 inhibitors (SGLT2is) can reduce important cardiorenal endpoints in type 2 diabetic adults without established cardiovascular disease (ECD), in those without heart failure (HF), and in those without chronic kidney disease (CKD). We searched PubMed, Embase, Cochrane C... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Aged', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Protective Factors', 'Randomized Controlled Trials as Topic', 'Risk Assessment', 'Risk Factors', 'Sodium-Glucose Transporter 2 Inhibitors', 'Treatment Outcome'] | 32,860,942 | 1 | SGLT2 inhibitors for prevention of cardiorenal events in people with type 2 diabetes without cardiorenal disease: A meta-analysis of large randomized trials and cohort studies. To investigate whether sodium glucose cotransporter 2 inhibitors (SGLT2is) can reduce important cardiorenal endpoints in type 2 diabetic adults... |
11/09/2023 | Primary antibiotic resistance in Helicobacter pylori in China: a systematic review and meta-analysis. | The incidence of Helicobacter pylori (HP) is 25-50% in developed countries and 80% in developing countries, including 56.2% in China. However, antibiotic resistance of HP is a threat to HP control. The purpose of this study was to comprehensively evaluate primary drug resistance of HP in China. The full text of reports... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Adult', 'Humans', 'Metronidazole', 'Clarithromycin', 'Levofloxacin', 'Helicobacter pylori', 'Helicobacter Infections', 'Drug Resistance, Bacterial', 'Anti-Bacterial Agents', 'China'] | 37,315,738 | 0 | Primary antibiotic resistance in Helicobacter pylori in China: a systematic review and meta-analysis. The incidence of Helicobacter pylori (HP) is 25-50% in developed countries and 80% in developing countries, including 56.2% in China. However, antibiotic resistance of HP is a threat to HP control. The purpose of this ... |
21/12/2023 | Vaccine acceptance, determinants, and attitudes toward vaccine among people experiencing homelessness: a systematic review and meta-analysis. | COVID-19 has caused millions of deaths globally, with vulnerable populations such as people experiencing homelessness (PEH) at higher risk. This systematic review and meta-analysis aims to identify the prevalence and key factors contributing to vaccine acceptance experienced by PEH. The protocol of this study was regis... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Female', 'Humans', 'Male', 'COVID-19 Vaccines', 'Ill-Housed Persons', 'Vaccination', 'Patient Acceptance of Health Care', 'Health Knowledge, Attitudes, Practice'] | 38,102,542 | 0 | Vaccine acceptance, determinants, and attitudes toward vaccine among people experiencing homelessness: a systematic review and meta-analysis. COVID-19 has caused millions of deaths globally, with vulnerable populations such as people experiencing homelessness (PEH) at higher risk. This systematic review and meta-analys... |
01/11/2022 | Specific alterations of gut microbiota in patients with membranous nephropathy: A systematic review and meta-analysis. | <b>Background:</b> The pathogenesis of idiopathic membranous nephropathy (IMN) has not yet been thoroughly clarified, and gut dysbiosis may be a contributor to IMN. However, the characterization of gut microbiota in patients with IMN remains uncertain. <b>Methods:</b> Cochrane Library, PubMed, China National Knowledge ... | ['Systematic Review'] | [] | 36,388,089 | 1 | Specific alterations of gut microbiota in patients with membranous nephropathy: A systematic review and meta-analysis. <b>Background:</b> The pathogenesis of idiopathic membranous nephropathy (IMN) has not yet been thoroughly clarified, and gut dysbiosis may be a contributor to IMN. However, the characterization of gut... |
18/03/2024 | Suicidal ideation, attempt, and its associated factors among adult HIV/AIDS patients in Ethiopia: A systematic review and meta-analysis study. | WHO statistics show that someone attempts suicide every three seconds and commits suicide every 40 seconds somewhere in the world. There is a scarcity of aggregate evidence in Ethiopia. The aim of this review was to assess the pooled prevalence of suicidal ideation, attempts, and associated factors among adult HIV/AIDS... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Adult', 'Humans', 'Female', 'Male', 'Suicidal Ideation', 'Ethiopia', 'Acquired Immunodeficiency Syndrome', 'HIV Infections', 'Prevalence', 'Opportunistic Infections'] | 38,484,019 | 0 | Suicidal ideation, attempt, and its associated factors among adult HIV/AIDS patients in Ethiopia: A systematic review and meta-analysis study. WHO statistics show that someone attempts suicide every three seconds and commits suicide every 40 seconds somewhere in the world. There is a scarcity of aggregate evidence in E... |
14/05/2020 | <b><sup>18</sup></b> F-Fluorodeoxyglucose positron-emission tomography for the investigation of malignancy in patients with suspected paraneoplastic neurologic syndromes and negative or indeterminate conventional imaging: a retrospective analysis of the Ontario PET Access Program, with systematic review and meta-analys... | Paraneoplastic neurologic syndrome (pns) is a rare condition indirectly caused by an underlying malignancy. In many cases, the malignancy is occult at the time of the pns diagnosis, and the optimal diagnostic modality to detect the underlying tumour is unclear. In the present study, we aimed to assess the utility of <s... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Male', 'Middle Aged', 'Ontario', 'Paraneoplastic Syndromes, Nervous System', 'Retrospective Studies', 'Sensitivity and Specificity', 'Young Adult'] | 31,548,813 | 0 | <b><sup>18</sup></b> F-Fluorodeoxyglucose positron-emission tomography for the investigation of malignancy in patients with suspected paraneoplastic neurologic syndromes and negative or indeterminate conventional imaging: a retrospective analysis of the Ontario PET Access Program, with systematic review and meta-analys... |
06/10/2020 | Chemical hazard for dental hygienists: a systematic review. | Dental hygienists (DHs) are professionals responsible for oral health. They deal with professional oral hygiene, counselling, and screening patients for oral health, as well as preventing and treating oral diseases. However, DH responsibilities and duties may vary worldwide, characterising changeable occupational expos... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Awareness', 'Dental Hygienists', 'Health Personnel', 'Humans', 'Latex', 'Occupational Exposure', 'Oral Health', 'Risk Assessment', 'Rubber', 'Workplace'] | 31,599,397 | 0 | Chemical hazard for dental hygienists: a systematic review. Dental hygienists (DHs) are professionals responsible for oral health. They deal with professional oral hygiene, counselling, and screening patients for oral health, as well as preventing and treating oral diseases. However, DH responsibilities and duties may ... |
22/10/2021 | Vitamin D and Muscle Health: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials. | The objective of this study was to investigate the effects of vitamin D supplementation versus placebo on muscle health. For this systematic review and trial-level meta-analysis of placebo-controlled trials, a systematic search of randomized controlled trials published until October 2020 was performed in Medline, Embas... | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Cholecalciferol', 'Dietary Supplements', 'Hand Strength', 'Humans', 'Muscles', 'Postural Balance', 'Randomized Controlled Trials as Topic', 'Time and Motion Studies', 'Vitamin D'] | 34,405,916 | 0 | Vitamin D and Muscle Health: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials. The objective of this study was to investigate the effects of vitamin D supplementation versus placebo on muscle health. For this systematic review and trial-level meta-analysis of placebo-controlled trials, a sy... |
11/08/2021 | Fluoroquinolones for BK viral complication after transplantation: Meta-analysis. | BK polyomavirus (BKV) causes two distinct complications after transplantation, hemorrhagic cystitis (BKV-HC) after hematopoietic stem cell transplantation (HSCT), and BKV-associated nephropathy (BKVAN) after kidney transplantation (KT). Although fluoroquinolones show efficacy against BKV proliferation in vitro, the cli... | ['Journal Article', 'Meta-Analysis'] | ['BK Virus', 'Bacteria', 'Drug Resistance, Bacterial', 'Fluoroquinolones', 'Humans', 'Kidney Transplantation', 'Polyomavirus Infections', 'Tumor Virus Infections', 'Viremia'] | 32,744,404 | 1 | Fluoroquinolones for BK viral complication after transplantation: Meta-analysis. BK polyomavirus (BKV) causes two distinct complications after transplantation, hemorrhagic cystitis (BKV-HC) after hematopoietic stem cell transplantation (HSCT), and BKV-associated nephropathy (BKVAN) after kidney transplantation (KT). Al... |
24/05/2021 | Sex Differences in Adaptations in Muscle Strength and Size Following Resistance Training in Older Adults: A Systematic Review and Meta-analysis. | Reductions in muscle size and strength occur with aging. These changes can be mitigated by participation in resistance training. At present, it is unknown if sex contributes to differences in adaptation to resistance training in older adults. The aim of this systematic review was to determine if sex differences are app... | ['Meta-Analysis', 'Systematic Review'] | ['Adaptation, Physiological', 'Aged', 'Aging', 'Female', 'Humans', 'Male', 'Muscle Strength', 'Muscle, Skeletal', 'Resistance Training', 'Sex Characteristics'] | 33,332,016 | 0 | Sex Differences in Adaptations in Muscle Strength and Size Following Resistance Training in Older Adults: A Systematic Review and Meta-analysis. Reductions in muscle size and strength occur with aging. These changes can be mitigated by participation in resistance training. At present, it is unknown if sex contributes t... |
05/03/2024 | Dietary indices underpinning front-of-pack nutrition labels and health outcomes: a systematic review and meta-analysis of prospective cohort studies. | Nutrient profiling systems are increasingly used to characterize the healthfulness of foods for front-of-package (FOP) labeling, which have been proposed as an effective public health strategy to help people make healthier food choices. This study aimed to review available evidence from cohort studies that evaluated th... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Cardiovascular Diseases', 'Consumer Behavior', 'Diet', 'Food Labeling', 'Food Preferences', 'Neoplasms', 'Nutritive Value'] | 38,145,705 | 0 | Dietary indices underpinning front-of-pack nutrition labels and health outcomes: a systematic review and meta-analysis of prospective cohort studies. Nutrient profiling systems are increasingly used to characterize the healthfulness of foods for front-of-package (FOP) labeling, which have been proposed as an effective ... |
08/09/2023 | Prevalence and risk factors of tuberculosis among people living with HIV/AIDS in China: a systematic review and meta-analysis. | To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in China. A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews a... | ['Meta-Analysis', 'Systematic Review', 'Journal Article'] | ['Humans', 'Acquired Immunodeficiency Syndrome', 'BCG Vaccine', 'Coinfection', 'Prevalence', 'Risk Factors', 'Tuberculosis', 'China'] | 37,674,103 | 0 | Prevalence and risk factors of tuberculosis among people living with HIV/AIDS in China: a systematic review and meta-analysis. To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in ... |
14/06/2024 | A systematic review of psychosocial and sex-based contributors to gender disparities in the United States across the steps towards kidney transplantation. | Persistent findings suggest women and patients identified as "female" are less likely to receive a kidney transplant. Furthermore, the limited research on transplantation among transgender and gender diverse people suggests this population is susceptible to many of the same psychosocial and systemic barriers. This revi... | ['Journal Article', 'Systematic Review', 'Review'] | ['Humans', 'Kidney Transplantation', 'United States', 'Female', 'Male', 'Healthcare Disparities', 'Sex Factors', 'Kidney Failure, Chronic'] | 38,729,062 | 1 | A systematic review of psychosocial and sex-based contributors to gender disparities in the United States across the steps towards kidney transplantation. Persistent findings suggest women and patients identified as "female" are less likely to receive a kidney transplant. Furthermore, the limited research on transplant... |
30/07/2023 | The value of functional magnetic resonance imaging in the evaluation of diabetic kidney disease: a systematic review and meta-analysis. | The diversity of clinical trajectories in diabetic kidney disease (DKD) has made blood and biochemical urine markers less precise, while renal puncture, the gold standard, is almost impossible in the assessment of diabetic kidney disease, and the value of functional magnetic resonance imaging in the evaluation of diabe... | ['Meta-Analysis', "Research Support, Non-U.S. Gov't", 'Systematic Review'] | ['Magnetic Resonance Imaging', 'Diabetic Neuropathies', 'Diffusion Tensor Imaging', 'Kidney', 'Diabetes Mellitus'] | 37,484,949 | 1 | The value of functional magnetic resonance imaging in the evaluation of diabetic kidney disease: a systematic review and meta-analysis. The diversity of clinical trajectories in diabetic kidney disease (DKD) has made blood and biochemical urine markers less precise, while renal puncture, the gold standard, is almost im... |
08/11/2022 | Autopsy findings of COVID-19 in children: a systematic review and meta-analysis. | Clinical features of COVID-19 range from mild respiratory symptoms to fatal outcomes. Autopsy findings are important for understanding COVID-19-related pathophysiology and clinical manifestations. This systematic study aims to evaluate autopsy findings in paediatric cases. We searched PubMed, EMBASE, and Cochrane Datab... | ['Meta-Analysis', 'Systematic Review', 'Journal Article', 'Review'] | ['Humans', 'Child', 'Infant', 'Child, Preschool', 'COVID-19', 'SARS-CoV-2', 'Autopsy', 'Lung', 'Thrombosis', 'Fibrin', 'Necrosis'] | 36,048,325 | 1 | Autopsy findings of COVID-19 in children: a systematic review and meta-analysis. Clinical features of COVID-19 range from mild respiratory symptoms to fatal outcomes. Autopsy findings are important for understanding COVID-19-related pathophysiology and clinical manifestations. This systematic study aims to evaluate aut... |
30/12/2022 | Risk of urinary stone formation associated to proton pump inhibitors: A systematic review and metanalysis. | Proton pump inhibitors are widely used as treatment of acid-related disorders. They are considered safe although their long-term use has been associated with some adverse effects including an increased propensity for urinary calculi formation. The aim of this study was to systematically review available data from studi... | ['Systematic Review', 'Meta-Analysis', 'Journal Article'] | ['Humans', 'Proton Pump Inhibitors', 'Magnesium', 'Urinary Calculi', 'Kidney Calculi', 'Citric Acid'] | 36,576,453 | 1 | Risk of urinary stone formation associated to proton pump inhibitors: A systematic review and metanalysis. Proton pump inhibitors are widely used as treatment of acid-related disorders. They are considered safe although their long-term use has been associated with some adverse effects including an increased propensity ... |
27/06/2022 | Reply to Aljabali et al. Comment on "Abbas et al. The Safety and Efficacy of Nusinersen in the Treatment of Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. <i>Medicina</i> 2022, <i>58</i>, 213". | We appreciate Ahmed Sami Aljabali and his colleagues for their interest and comments [...]. | ['Journal Article', 'Meta-Analysis', 'Systematic Review'] | ['Humans', 'Muscular Atrophy, Spinal', 'Oligonucleotides', 'Randomized Controlled Trials as Topic'] | 35,744,055 | 0 | Reply to Aljabali et al. Comment on "Abbas et al. The Safety and Efficacy of Nusinersen in the Treatment of Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. <i>Medicina</i> 2022, <i>58</i>, 213". We appreciate Ahmed Sami Aljabali and his colleagues for their interest and c... |
24/11/2022 | Kidney injury rates after unilateral nephrectomy in childhood-a systematic review and meta-analysis. | Unilateral nephrectomy is a relatively common procedure in children which results in a solitary functioning kidney (SFK). Living with an SFK predisposes to kidney injury, but it remains unknown which children are most at risk. We aimed to investigate kidney injury rates in patients who underwent unilateral nephrectomy ... | ['Meta-Analysis', 'Systematic Review', 'Journal Article', "Research Support, Non-U.S. Gov't"] | ['Humans', 'Nephrectomy', 'Kidney', 'Proteinuria', 'Hypertension'] | 35,099,015 | 1 | Kidney injury rates after unilateral nephrectomy in childhood-a systematic review and meta-analysis. Unilateral nephrectomy is a relatively common procedure in children which results in a solitary functioning kidney (SFK). Living with an SFK predisposes to kidney injury, but it remains unknown which children are most a... |
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