{"sha256": "d6a869a9050d6ee2ced2dd0a9c63a28954c9f4ffb3880ae5d465bce7a90ad6f9", "doi": "10.1177/2158244015575557", "title": "On the Sidelines: Labor Force Participation of Prime Age Men", "author": "Joseph S. Falzone", "keyword": "labor force participation, labor market, human capital, gender, labor/leisure choice ", "abstract": "For more than a century, labor force participation rates of men have been falling, representing one of the most significant trends in the labor market. The concomitant rise in non-participation of prime age men has been attributed to both cyclical and structural factors. Over the past two decades, participation rates of prime age men have fallen by almost 5%, representing both a problem and a paradox. The author describes changes in men’s labor force participation, focusing on human capital and demographic variables, and then estimates non-participation of prime age men over selected years. A model of labor/ leisure choice and estimation of non-participation over selected years is presented using a probit model.", "pub_time": "2015"}
{"sha256": "35a6a7cc42ef7fba435f762fcaa1f0cef9aebd5c071d26e17ff01e759d9dc321", "doi": "10.1177/0267659117706834", "title": "Air in intravenous lines: a need to review old opinions", "author": "Gerard J Myers RT, CCP Emeritus", "keyword": "intravenous lines，air embolism,Paradoxical Air Emboli, PAE,venous air emboli, VAE,endothelial glycocalyx,intravenous-line air filters", "abstract": "", "pub_time": "2017"}
{"sha256": "35b2a8c77dbb4c711dbc0b59d470b206f1e949def831da5f2ac564df39251303", "doi": "10.1177/1757177420963829", "title": "Ability of chlorhexidine, octenidine, polyhexanide and chloroxylenol to inhibit metabolism of biofilm-forming clinical multidrug-resistant organisms", "author": "Frank Günther, Brigitte Blessing, Ulrike Dapunt, Alexander Mischnik, Nico T Mutters", "keyword": "Chlorhexidine, octenidine, multidrug resistant gram-negatives, hospital-acquired infection, MRSA, biofilm", "abstract": " Purpose: This in vitro study was designed to determine if standard antiseptics used for skin and environmental surface cleansing can disrupt the metabolic activity (as a measure of viability) of multidrug-resistant gram-negative bacteria, methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus isolates within their native biofilms. Methods: Sixty clinical isolates of multidrug-resistant bacteria were selected for testing in different chlorhexidine gluconate, octenidine, polyhexanide and chloroxylenol concentrations. Metabolic inhibition of biofilm for each clinical isolate was analysed using a biofilm viability assay. Results: Chlorhexidine gluconate (mean = 83.8% ± 9.8%) and octenidine (mean = 84.5% ± 6.8%) showed the greatest efficacy against biofilms of the tested microorganisms, with the greatest efficacies against MRSA. The antiseptics demonstrated the least efficacy against biofilms of Pseudomonas aeruginosa. Conclusion: Chlorhexidine gluconate and octenidine showed the greatest level of bacterial metabolic inhibition and were statistically equivalent. Polyhexanide was more effective than chloroxylenol, but both were inferior to chlorhexidine gluconate and octenidine against the tested organisms", "pub_time": "2021"}
{"sha256": "d6a4e86c49b806fd87b2ba904e163ac10d79f602dd7ba4c40bc3cc05b8b47cc6", "doi": "10.1177/23779608221119124", "title": "The Impact of Work Environment on Nurses’ Compassion: A Multicenter Cross-Sectional Study", "author": "Sepideh Naseri, MSc , Mansour Ghafourifard, PhD, Akram Ghahramanian, PhD", "keyword": "compassionate care, compassion, critical care nurses, work environment", "abstract": " Introduction: Compassionate care is considered as the main part of the nurses’ identity and a core component of nursing care. One clinical environment where patients experience a lot of pain and nurses play a vital role in delivering care is the intensive care unit (ICU). Objective: Considering the importance of compassionate care in intensive care units, this study aimed to assess the relation ship between the work environment and nurses’ compassion in intensive care units. Methods: In this cross-sectional survey, a total of 235 nurses were randomly selected from the intensive care units of four educational hospitals of Tabriz University of Medical Sciences from January to March 2021. Data were collected by demo graphic questionnaire, the Sussex-Oxford Compassion for Others Scale (SOCS-O) and the Practice Environment Scale of the Nursing Work Index (PES-NWI). Results: The results showed that there was a significant and inverse relationship between the patient per nurse ratio and the mean score of nurses’ compassion (P<.05). Moreover, Pearson correlation coefficient showed that the mean total score of the nursing work index had a significant positive relationship with the mean score of the compassion for others (r = 0.16, P = .016). Conclusion: Health care managers and leaders should pay more attention to the promotion of nurses’ working environ ments and they should remove the organizational barriers of compassionate care delivery", "pub_time": "2022"}
{"sha256": "d6a637a2ee4e18fac9384d7d25bd92ee376ec5002c56718a277f07e4e6c170d1", "doi": "10.4081/jphr.2021.2144", "title": "The presence of Leptospira sp. and leptospirosis risk factor analysis in Boyolali district", "author": "Yuliani Setyaningsih, Nurdin Bahtiar, Apoina Kartini, Siti Fatimah Pradigdo, Lintang Dian Saraswati", "keyword": "Leptospira sp., leptospirosis, water bodies", "abstract": "Background: Leptospirosis is a health problem that causes death in Indonesia. In 2017, Boyolali District was reported that the number of leptospirosis cases reached 40.62 per 100,000 popula tion with a CFR of 23.52%. The determination of risk factors and Leptospira bacteria's presence in the body of water plays an essen tial role in the transmission of leptospirosis. Design and methods: This study aims to determine the risk factors and Leptospira bacteria's presence in water bodies in Boyolali District. This research is descriptive research with a sur vey method using a cross-sectional design and an analytical study using an observational method with a case-control approach. The sample was 100 water samples from wells, rivers, and paddy fields in endemic and non-endemic areas of leptospirosis. This study's population was 34 people with leptospirosis in Boyolali Regency in January 2017 - August 2018. Results: There was a significant relationship between lep tospirosis incidence in the Boyolali Regency with garbage, the pet presence, a history of injuries, and field activity. Leptospira bac teria are found in rivers (18.18%) and rice fields (6.67%), while in sub-districts with cases occur almost every year. Leptospira are found in wells (18.18%) and rice fields (6.67%). Conclusions: People should pay more attention to home sani tation and the surrounding environment to avoid leptospirosis.", "pub_time": "2021"}
{"sha256": "d6b29390bff137f116bc4e3808b25bd8f743642239ea20ea38a76debac73915f", "doi": "10.1177/1094428116642013", "title": "The Added Value of Neuroscience Methods in Organizational Research", "author": "David A. Waldman, Danni Wang, Virgil Fenters", "keyword": "neuroscience, individual characteristics, teams", "abstract": " Historically, the lack of availability and prohibitive expense of brain imaging technology have limited the application of neuroscience research in organizational settings. However, recent advances in technology have made it possible to use brain imaging in organizational settings at relatively little expense and in a practical manner to further research efforts. In this article, we weigh the advantages and disadvantages of neuroscience applications to organizational research. Further, we present three key methodological issues that need to be considered with regard to such applications: (a) level of assessment, (b) intrinsic versus reflexive brain activity, and (c) the targeting of brain region(s) or networks. We also pose specific examples of how neuroscience may be applied to various topical areas in organizational behavior research at both individual and team levels", "pub_time": "2019"}
{"sha256": "35d31951cebad4df26dec994bd1ff264eb1fec77fe890f11acf5eb406cad355d", "doi": "10.1177/0022185609353980", "title": "Symposium Introduction Labour, Capital and Change: Selected Papers from AIRAANZ 2009", "author": "John Lewer, Shaun Ryan", "keyword": "", "abstract": "", "pub_time": "2009"}
{"sha256": "35d77e2832e7d0eb9917866cd08388c3a241211521a507268c51c7f0ce55a57e", "doi": "10.1177/1078087420984241", "title": "Beyond Neoliberalism: A Policy Agenda for a Progressive City", "author": "Meghan Joy, Ronald K. Vogel", "keyword": "progressive city, public transit and equity, climate change, affordable housing, work and income", "abstract": " The urban crisis—poverty and inequality, un—and under-employment, inadequate and unaffordable housing and public transportation, pollution and climate disasters—is the result of the failure of the neoliberal agenda to produce adequate funds and capacities to ensure the provision of services necessary for the city to function and its residents to thrive, especially the most vulnerable, and increasingly, the middle class. In the last few years, there appears to be a potential for a new more radical direction in urban policy. Yet, urban scholars and practitioners have been slow to notice the new possibilities that reopens the question of whether cities may engage in redistributive policies. In reviewing the history and current practice of progressive politics and policy in cities, this paper explores what a policy agenda for a progressive city might entail and identifies themes and questions for a renewed urban politics research agenda.", "pub_time": "2021"}
{"sha256": "a15fe6303692a5953ab2c22e92353e37881a101e30202df73305533116c0e9ca", "doi": "", "title": "Three-Dimensional Structure of Dimeric Human Recombinant Macrophage Colony-Stimulating Factor", "author": "Jayvardhan Pandit, Andrew Bohm, Jarmila Jancarik, Robert Halenbeck, Kirston Koths, Sung-Hou Kim", "keyword": "", "abstract": "", "pub_time": "1992"}
{"sha256": "35b98cb6c95e257751324d60f2d5c59edef010d0e98a16472dd914141c8bba5b", "doi": "", "title": "PHTHALIDEISOQUINOLINE ALKALOIDS AND RELATED COMPOUNDS", "author": "D. B. MacLean", "keyword": "", "abstract": "", "pub_time": "1985"}
{"sha256": "35bd48c6d8221a9ee0304d65a9e50cf4c82f4b21a636ea1a9064f133b1a42b6d", "doi": "10.1191/1477153504li105oa", "title": "The contribution of vehicle lights in urban and peripheral urban environments", "author": "A Bacelar", "keyword": "", "abstract": "", "pub_time": "2003"}
{"sha256": "00093542a436d1aea90f42bb7537c5bbf23eaf4d322c9c99740fb2caf19aea11", "doi": "", "title": "THE USE OF REACTIVE COATINGS ON FILTERS FOR THE REMOVAL OF INDOOR GASEOUS POLLUTANTS", "author": "H.D. Gesser, I.E. Gesser, P. Wong", "keyword": "", "abstract": "", "pub_time": "1992"}
{"sha256": "0010b5b39ccc806c646971bfbdc3c1a708a71a0d969e740d1c1ce0e7d4798956", "doi": "", "title": "STUDIES ON THE STEREOSELECTIVITY AND SUBSTITUTED GROUPS OF (+)-CAMPHOR DERIVATIVES", "author": "GUO PENG, LIU GUI-LAN, JIANG YAO-ZHONG, ZHOU ZHONG-YUAN", "keyword": "(+)-camphor derivatives, configuration, stereoselectivity", "abstract": "From (+)-camphor, six new (+)-camphor derivatives were synthesized. According to the structure and chemical properties of the derivatives, the relation between the substituted groups and the stereoselectivity of alkylation and reduction was examined. It is found that the chemical shift of protons of C(8), C(9) methyl groups and chemical properties of carbonyl O(2) are associated with the substituted groups.", "pub_time": "1990"}
{"sha256": "000f8b157ecb2aa14b3d49e6a51f722d116cec3f90193714c7354e38df433772", "doi": "", "title": "術後に癌性胸膜炎を発症し長期生存中の乳癌の 1 例", "author": "渕之上祐子, 堀口和美, 山下年成, 堀口慎一郎,  黒井克昌", "keyword": "再発乳癌, 癌性胸膜炎, 長期生存", "abstract": "症例は，62歳時に右乳癌T1N0M0 StageⅠの診断で右乳房部分切除・腋窩リンパ節 郭清を施行された．病理は浸潤性乳管癌，浸潤径 ８ mm，リンパ節転移陰性，enzyme immunoassay（EIA）でER（－），PgR（－）であった．術後残存乳房照射を行った．術 後 ３ 年目に胸水を認め，細胞診で乳癌術後癌性胸膜炎と診断した．CTで他臓器転移を 認めなかった．再発時に原発巣の免疫染色を再検し，ER（＋），PgR（－），HER2（－） と判明した．胸膜癒着術後，doxifluridine（ ５ ’DFUR）＋medroxyprogesteroneacetate （MPA）＋cyclophosphamide（CPA）の内服を開始した．その後増悪なく再発後 ４ 年 目に治療を中止した．以降 ９ 年経過した現在まで寛解を維持している．今回，癌性胸膜 炎発症後13年間に亘り長期生存を得られている １ 例を経験したので報告する.", "pub_time": "2016"}
{"sha256": "00084b7788db02026a6d27fe568d8414ad12f95471d89bf3551f0ea213a00817", "doi": "", "title": "Double-Tracer Radiography with Sulfur-35 and Phosphorus-32 Using Imaging Plates in Brassica napus L.", "author": "Hiroki ISHIBASHI, Masato YAMAWAKI, Atsushi HIROSE, Akihiko NODA, Satomi KANO, Takayuki SAITO, Sayaka MASUDA, Syohei SEYAMA, Keitaro TANOI, Tomoko M. NAKANISHI", "keyword": "double-tracer radiography, sulfur-35, sulfuric acid, phosphorus-32, phosphoric acid, Brassica napus L", "abstract": "We present double-tracer autoradiography with ³⁵S and ³²P using imaging plates and an aluminum plate to visualize the individual distribution of sulfur and phosphorus in Brassica napus L.. Because of the different attenuation efficiencies of β-rays emitted from ³⁵S and ³²P, the specific image of ³²P was taken when an aluminum plate was placed between the sample and the imaging plate. The specific image of ³⁵S was obtained by subtracting the ³²P image from the ³⁵S and ³²P image. It was observed that high amount of ³⁵S was distributed at the edge of the leaves and in root tips. The ³²P was distributed throughout the whole plant and it was found that the phosphorous amount was higher at the shoot apical meristems than those in leaves.", "pub_time": "2010"}
{"sha256": "00103e245fcdf4f12707af4091026a9e10f770f77a5c75d0f1cfe23157ebaaa0", "doi": "", "title": "Effect of Cardiac Rehabilitation in Preventing Implantable Cardioverter Defibrillator Therapy in Patients with Reduced Left Ventricular Ejection Fraction", "author": "Ko OGAWA, Mitsuharu KAWAMURA*, Shinji KOBA, Yumi MUNETSUGU, Yuya NAKAMURA, Akinori OCHI, Koichiro INOKUCHI, Yuya YOKOTA, Tatsuya ONUKI, Fumiyoshi TSUNODA, Makoto SHOJI, Norikazu WATANABE and Youichi KOBAYASHI", "keyword": "cardiac rehabilitation, ICD, therapy event, inappropriate therapy event", "abstract": "In patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronization therapy defibrillators (CRT-D), appropriate and inappropriate shocks lead to a higher risk of mortality. Cardiac rehabilitation (CR) is an established therapy for patients with ischemic heart disease and/or congestive heart failure. However, it is unclear whether CR could reduce the need for device therapies. The purpose of the present study was to investigate whether CR reduces device therapies and mortality in patients with severe cardiac dysfunction and ICD or CRT-D. Of the 390 patients who were implanted with an ICD or CRT-D between 1998 and 2015, 222 (178 men, 44 women) with a low ejection fraction (EF; < 45%) were investigated in this present study. The study cohort was divided into two groups, the CR group (n = 70) and the non-CR group (n = 152), and baseline clinical characteristics of the two groups were compared. Furthermore, the number of all device therapies, appropriate therapies, inappropriate therapies, and mortality for 1 year after ICD or CRT-D implantation were compared. There were no significant differences in baseline characteristics between the CR and non-CR groups (e.g. age 68.5 vs 66.2 years [P = 0.16]; EF 27.9% vs 29.7% [P = 0.14]). Kaplan-Meier analysis revealed that all device therapy events and inappropriate therapy events were lower in the CR than non-CR group (P = 0.01 and P = 0.03, respectively). Appropriate therapy events and mortality did not differ significantly between the two groups (5.7% vs 13.1% [P = 0.09] and 11.4% vs 17.0% [P = 0.28], respectively). CR may have beneficial effects in preventing therapy events, especially inappropriate therapy, in patients with an ICD or CRT-D.", "pub_time": "2017"}
{"sha256": "001a9d63aee0c66b5f3920b00dc766f53cb60ac344d3983a56d1259156051121", "doi": "", "title": "II. 治療の進歩\n2. 感染症治療時の全身管理", "author": "古西満, 善本英一郎, 三笠桂一, 成田亘啓", "keyword": "敗血症、ショック、播種性血管内凝固症候群（DIC）、低アルブミン血症", "abstract": "敗血症の臨床像は患者の基礎疾患により異なり、ショックや播種性血管内凝固症候群（DIC）を合併した症例は予後が不良で、敗血症治療時には合併症治療も行なう必要がある。敗血症性ショックの病態は末梢血管拡張と血管透過性亢進による循環障害で、治療の基本は体液補正である。敗血症によるDICは線溶抑制型で、より臓器障害を起こし易いので積極的な治療が求められる。したがって感染症治療時には原因治療とともに全身管理が重要な課題となる。", "pub_time": "1998"}
{"sha256": "0002214a114ae8d8d49606d7122d1c5aa20e0ee12d160739e517865a65f3f927", "doi": "", "title": "Weiss-Weinstein bound of frequency estimation error for very weak GNSS signals", "author": "Xin Zhang, Xingqun Zhan, Jihong Huang, Jiahui Liu, Yingchao Xiao", "keyword": "", "abstract": "Tightness remains the center quest in all modern estimation bounds. For very weak signals, this is made possible with judicial choices of prior probability distribution and bound family. While current bounds in GNSS assess performance of carrier frequency estimators under Gaussian or uniform assumptions, the circular nature of frequency is overlooked. In addition, of all bounds in Bayesian framework, Weiss-Weinstein bound (WWB) stands out since it is free from regularity conditions or requirements on the prior distribution. Therefore, WWB is extended for the current frequency estimation problem. A divide-and-conquer type of hyperparameter tuning method is developed to level off the curse of computational complexity for the WWB family while enhancing tightness. Synthetic results show that with von Mises as prior probability distribution, WWB provides a bound up to 22.5% tighter than Ziv-Zakaï bound (ZZB) when SNR varies between -3.5 dB and -20 dB, where GNSS signal is deemed extremely weak.", "pub_time": ""}
{"sha256": "0003f32dc40c99ec88c911adee9b435bff0ea4af9d708edbd87693075de481e3", "doi": "", "title": "ADI schemes for valuing European options under the Bates model", "author": "Karel J. in ’t Hout, Jari Toivanen", "keyword": "partial integro-differential equations, operator splitting methods, alternating direction implicit schemes, stability, Bates model", "abstract": "This paper is concerned with the adaptation of alternating direction implicit (ADI) time discretization schemes for the numerical solution of partial integro-differential equations (PIDEs) with application to the Bates model in finance. Three different adaptations are formulated and their (von Neumann) stability is analyzed. Ample numerical experiments are provided for the Bates PIDE, illustrating the actual stability and convergence behaviour of the three adaptations.", "pub_time": "2017"}
{"sha256": "000fd02da75b752c19b8a61124f0d3947c967314ea0493045c83135d6c760998", "doi": "", "title": "A time-domain numerical method for Biot-JKD poroelastic waves in 2D heterogeneous media", "author": "Emilie Blanc, Guillaume Chiavassa, Bruno Lombard", "keyword": "bers: 43.20.-Gp Keywords: porous media, elastic waves, Biot-JKD model, fractional derivatives, numerical modeling, diffusive representation, finite difference methods, Cartesian grid", "abstract": "Tightness remains the center quest in all modern estimation bounds. For very weak signals, this is made possible with judicial choices of prior probability distribution and bound family. While current bounds in GNSS assess performance of carrier frequency estimators under Gaussian or uniform assumptions, the circular nature of frequency is overlooked. In addition, of all bounds in Bayesian framework, Weiss-Weinstein bound (WWB) stands out since it is free from regularity conditions or requirements on the prior distribution. Therefore, WWB is extended for the current frequency estimation problem. A divide-and-conquer type of hyperparameter tuning method is developed to level off the curse of computational complexity for the WWB family while enhancing tightness. Synthetic results show that with von Mises as prior probability distribution, WWB provides a bound up to 22.5% tighter than Ziv-Zakaï bound (ZZB) when SNR varies between -3.5 dB and -20 dB, where GNSS signal is deemed extremely weak.", "pub_time": "2012"}
{"sha256": "00108d032f4e91846e24aff2e997bd1fd0fbfcde96ff2c00181ac3fba05dfd41", "doi": "", "title": "VALUE-DISTRIBUTION OF THE RIEMANN ZETA-FUNCTION ALONG ITS JULIA LINES", "author": "JORN STEUDING, ADE IRMA SURIAJAYA", "keyword": "Riemann zeta-function, value-distribution, critical line, Julia line", "abstract": "For an arbitrary complex number a 6= 0 we consider the distribution of values of the Riemann zeta-function ζ at the a-points of the function ∆ which appears in the functional equation ζ(s) = ∆(s)ζ(1 − s). These a-points δa are clustered around the critical line 1/2 + iR which happens to be a Julia line for the essential singularity of ζ at infinity. We observe a remarkable average behaviour for the sequence of values ζ(δa).", "pub_time": "2020"}
{"sha256": "0014e316ee3355c55c6221f3b4a482bce430d5d45b79a3135bfc6ed30ab1e137", "doi": "", "title": "MgNO: E fficient Parameterization of Linear Operators via Multigrid", "author": "Juncai He, Xinliang Liu, Jinchao Xu", "keyword": "", "abstract": "In this work, we propose a concise neural operator architecture for operator learning. Drawing an analogy with a conventional fully connected neural network, we define the neural operator as follows: the output of the ii-th neuron in a nonlinear operator layer is defined by Oi(μ)=σ(∑jWijμ+Bj)Oi(μ)=σ(∑jWijμ+Bj). Here, WijWij denotes the bounded linear operator connecting the jj-th input neuron to the ii-th output neuron, and the bias BjBj takes the form of a function rather than a scalar. Given its new universal approximation property, the efficient parametrization of the bounded operators between two neurons (Banach spaces) plays a critical role. As a result, we introduce MgNO, utilizing multigrid structures to parameterize these linear operators between neurons. This approach offers both mathematical rigor and practical expressivity. Additionally, MgNO obviates the need for conventional lifting and projecting operators typically required in previous neural operators. Moreover, it seamlessly accommodates diverse boundary conditions. Our empirical observations reveal that MgNO exhibits superior ease of training compared to other CNN-based models, while also displaying a reduced susceptibility to overfitting when contrasted with spectral-type neural operators. We demonstrate the efficiency and accuracy of our method with consistently state-of-the-art performance on different types of partial differential equations (PDEs).", "pub_time": "2023"}
{"sha256": "a0ee9d828a85d7fd061c3398b8167afc895ea98030021ecd5edef27a7dd0ebcf", "doi": "", "title": "Inherently Unstable Internal Gravity Waves due to Resonant Harmonic Generation", "author": "Y. Liang, Ahmad Zareei, M.-Reza Alam", "keyword": "", "abstract": " Here we show that there exist internal gravity waves that are inherently unstable, that is, they cannot exist in nature for a long time. The instability mechanism is a one-way (irreversible) harmonic-generation resonance that permanently transfers the energy of an internal wave to its higher harmonics. We show that, in fact, there are countably infinite number of such unstable waves. For the harmonic-generation resonance to take place, nonlinear terms in the free surface boundary condition play a pivotal role, and the instability does not obtain for a linearly-stratified fluid if a simplified boundary condition such as rigid lid or linear form is employed. Harmonic-generation resonance presented here also provides a mechanism for the transfer of the energy of the internal waves to the higher-frequency part of the spectrum where internal waves are more prone to breaking, hence losing energy to turbulence and heat and contributing to oceanic mixing", "pub_time": "2016"}
{"sha256": "a0f933db75aaefdf92e79076ccc8d25cf97e25a8597a93872f1878354e63051c", "doi": "", "title": "Towards computing low-makespan solutions for multi-arm multi-task planning problems", "author": "Valentin N. Hartmann, Marc Toussaint", "keyword": "", "abstract": " We propose an approach to find low-makespan solutions to multi-robot multi-task planning problems in environments where robots block each other from completing tasks simul taneously. Weintroduce a formulation of the problem that allows for an approach based on greedy descent with random restarts for generation of the task assignment and task sequence. We then use a multi-agent path planner to evaluate the makespan of a given assignment and sequence. The planner decomposes the problem into multiple simple subproblems that only contain a single robots and a single task, and can thus be solved quickly to produce a solution for a fixed task sequence. The solutions to the subproblems are then combined to form a valid solution to the original problem. We showcase the approach on robotic stippling and robotic bin picking with up to 4 robot arms. The makespan of the so lutions found by our algorithm are up to 30% lower compared to a greedy approach.", "pub_time": "2023"}
{"sha256": "000026afa59a17089537ea859532054704c42a29b72aefe77965d79c404909a4", "doi": "10.1080/00221589.1992.11516241", "title": "Chilling unit accumulation and forcing effects on carbohydrates of young apple rootstocks", "author": "Julia L. Whitworth, E. Young", "keyword": "", "abstract": "", "pub_time": "1992"}
{"sha256": "0000f42fad1b77d31495b0636618cbb257bc281c3bd5d0ba699c96e922539023", "doi": "", "title": "Fusobacterium nucleatum Involvement in Adult Periodontitis and Possible Modification of Strain Classification", "author": "Christine G. Roques, Said El Kaddouri, Pierre Barthet, Jean-François Duffort, Michel Arellano", "keyword": "Fusobacterium nucleatum, hemagglutination, fatty acids, short-chain, periodontitis/microbiology", "abstract": "", "pub_time": "2000"}
{"sha256": "00029b9880350149fcd2f6276ac53f418f2511a66d2837027c9148f8bfa5bbd4", "doi": "", "title": "СИНТЕЗ И СВОЙСТВА ХРОМАТОГРАФИЧЕСКИХ СОРБЕНТОВ С ПРИВИТЫМИ СЛОЯМИ АЦЕТИЛАЦЕТОНАТА НИКЕЛЯ", "author": "Е.А. Пахнутова, Ю.Г. Слижов", "keyword": "Газовая хроматография, хелатсодержащие сорбенты, ацетилацетон", "abstract": "Синтезированы хелатсодержащие хроматографические сорбенты с привитыми слоями ацетилацетоната никеля с помощью последовательной сборки на поверхности носителя через стадию хлорирования силикагеля. Исследованы их структурные и хроматографические характеристики физико-химическими методами. Показано, что полученные сорбенты могут применяться в газовой хроматографии для разделения легких олефиновых, ароматических, насыщенных углеводородов, а также спиртов, альдегидов и кетонов.", "pub_time": "2013"}
{"sha256": "0002b08ab275b904916d2b57807236027fee9c29351203de760f07e21b195b50", "doi": "", "title": "Collaborative Sensing for Cognitive Radio under Log-Normal Shadowing ", "author": "Nedaa Al Hussien, Mohammed Abdel-Hafez, Khaled Shuaib", "keyword": "spectrum sensing, cognitive radio, log-normal shadowing, probability of detection, collaborative sensing, soft (data) combining, hard (decision) combining", "abstract": "Spectrum sensing is an essential function in cognitive radio networks. It defines spectrum opportunities that can be used by secondary users to increase spectrum utilization. However, sensing performance is highly affected by shadowing. In this paper, sensing in a log-normal shadowing environment is investigated, where a closed-form for the probability of detection based on Gauss-Hermite integration is derived, and the accuracy of this form is studied. In addition, collaborative sensing in log-normal shadowing is addressed, where the performance of different soft combining schemes is evaluated via Complementary Receiver Operating Characteristic (CROC) curves.", "pub_time": "2015"}
{"sha256": "0002bb8b1881c1f78adcc1af00f6ee2507514ed7c20247f40e100d89941b85db", "doi": "10.1080/24740527.2017.1412254", "title": "To look or not to look during vaccination: A pilot randomized trial", "author": "Priyanjali Mithal, Pamela Simmons, Tessa Cornelissen, Horace Wong, Rebecca Pillai Riddell, C. Meghan McMurtry, Lisa Burry, Derek Stephens, Anna Taddio", "keyword": "vaccination, pain, fear, needle, looking preference", "abstract": " Background: Clinicians commonly advise patients to look away fromthe needle during vaccinations;however, thisrecommendationisnotevidencebased. Aim: Theaimof thisstudywas todeterminewhether lookingat theneedleversus looking awayaffectspainandfearduringvaccinations inadults. Methods:Thiswasapilotrandomizedtwo-groupparallel trialwithuniversitystudentsreceiv inginfluenzavaccinations.Participantswerestratifiedaccordingtotheir initialneedle-looking preferenceandrandomlyassignedtoeither lookatversusawayfromtheneedle.Participants self-reportedtheirpainandfearduringvaccination. Results:Ofthe184subjectswhoagreedtoparticipate,160wereenrolled;66%werefemale.A three-wayanalysisofvariance(ANOVA;Lookingallocationassignment×Lookingpreference× Sex) revealedasignificantmaineffectof lookingallocationassignmentonfear (P=0.025); thosewhowererandomizedtolookhadhigherfearscoresthanthosewhowererandomized tolookaway.Therewasalsoasignificantmaineffectof lookingpreferenceonfear(P<0.001); thosewhopreferredtolookawayhadhigher fear scores thanthosewhopreferredtolook. Therewasnoevidenceofaneffectof lookingallocationassignmentor lookingpreferenceon pain.Therewasasignificantmaineffectofsexonfearandpain,withfemalesreportinghigher painand fear scores thanmales (P=0.017 andP=0.001, respectively). Therewereno significant interactions. Conclusion: Thesepreliminary findings suggest thatadvising individuals to lookaway from theneedlereducesfear.Alargertrial includingmoreindividualsandadifferentpopulationis recommendedtoconfirmtheresults", "pub_time": "2018"}
{"sha256": "0002d012d42d67ba8a3cdaf611c01677808dc3fbaa3999d2f70e72e67fc271ec", "doi": "", "title": "LA CLASSE COMME REPRÉSENTATION ET COMME VOLONTÉ ", "author": "Raymond Aron", "keyword": "", "abstract": "La discussion scientifique sur le problème des classes continue d'être empoisonnée par les arrière-pensées teurs et commentateurs idéologiques qu'au- se prêtent réciproquement. A qui écrit un livre sur les classes et la lutte de classes, la première posée est celle de la conformité question des thèses présentées avec la pensée marxiste, quitte pour chaque ou de la non-conformité à se faire son interprétation interrogateur « pensée marxiste », entre les textes de jeunesse abandonnés « à la personnelle de la critique des souris » et tournés en dérision V Idéologie allemande, par Marx lui-même et les textes de YAnti-Dühring, dès approuvés par Marx mais désavoués par la plupart des philosophes qui, en France, se déclarent marxistes (mais non marxistes-léninistes), c'est-à-dire fidèles au vrai Marx. Le vrai Marx étant le Marx qui a dit ce qu'ils tiennent pour la vérité, ils appliquent sans le savoir ou, en tout cas, sans l'avouer la devise d'Alain : le vrai Marx est le Marx qui est vrai. Peut-être la discussion est-elle empoisonnée, les soupçons idéologiques, autant que par par l'équivoque du vocabulaire. Quand on lit sous la plume d'un sociologue (Alain Touraine), que classes et civilisation industrielle sont des réalités incompatibles et sous la plume d'un autre sociologue (Georges Gurvitch) que toute société industrialisée comporte des classes et des luttes de classes, on aurait tort d'en conclure immédiatement que les deux propo- sitions portent sur les mêmes faits et résultent d'un déchiffrement radicalement autre de la réalité. Pour une part qui reste à déter- miner, le dissentiment porte sur le vocabulaire, sur le sens donné aux mots, ce qui n'exclut pas qu'entre les définitions et la vision de la société le lien ne soit significatif et étroit. Nous tâcherons, dans la communication la méthode qui permet, nous semble-t-il, adoptées qui suit, d'esquisser de tourner les obstacles", "pub_time": "1965"}
{"sha256": "0003eaf45da925c0e5271435bbe88876e0553b5cc5df604f803a54f9a5ab62c9", "doi": "", "title": "Identification and Characterization of NDT 9513727 [N,N-bis(1,3-Benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a Novel, Orally Bioavailable C5a Receptor Inverse Agonist", "author": "Robbin M. Brodbeck, Daniel N. Cortright, Andrzej P. Kieltyka, Jianying Yu, Carolyn O. Baltazar, Marianne E. Buck, Robin Meade, George D. Maynard, Andrew Thurkauf, Du-Shieng Chien, Alan J. Hutchison, James E. Krause", "keyword": "", "abstract": " The complement system represents an innate immune mech anism of host defense that has three effector arms, the C3a receptor, the C5a receptor (C5aR), and the membrane attack complex. Because of its inflammatory and immune-enhancing properties, the biological activity of C5a and its classical recep tor have been widely studied. Because specific antagonism of the C5aR could have therapeutic benefit without affecting the protective immune response, the C5aR continues to be a prom ising target for pharmaceutical research. The lack of specific, potent and orally bioavailable small-molecule antagonists has limited the clinical investigation of the C5aR. We report the dis covery of NDT 9513727 [N,N-bis(1,3-benzodioxol-5-ylmethyl) 1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a small molecule, orally bioavailable, selective, and potent inverse agonist of the human C5aR. NDT 9513727 was discovered based on the integrated use of in vitro affinity and functional assays in conjunction with medicinal chemistry. NDT 9513727 inhibited C5a-stimulated responses, including guanosine 5-3 O-(thio)triphosphate binding, Ca2 mobilization, oxidative burst, degranulation, cell surface CD11b expression and chemotaxis in various cell types with IC50 s from 1.1 to 9.2 nM, respectively. In C5a competition radioligand binding experiments, NDT 9513727 exhibited an IC50 of 11.6 nM. NDT 9513727 effectively inhibited C5a-induced neutropenia in gerbil and cynomolgus macaque in vivo. The findings suggest that NDT 9513727 may be a promising new entity for the treatment of human inflammatory diseases", "pub_time": "2008"}
{"sha256": "0003ec1aae416acc7a291de0b743bede9b53dda5e08280d672ca2565a2a3635a", "doi": "10.3382/ps/pez444", "title": "Chromium propionate in broilers: human food and broiler safety", "author": "J. W. Spears, K. E. Lloyd, C. A. Pickworth, Y. L. Huang, K. Krafka,  J. Hyda, J. L. Grimes", "keyword": "chromium, broilers, tissue chromium", "abstract": "Chromium propionate (Cr Prop) is approved by the U.S. Food and Drug Administration Center for Veterinary Medicine for supplementation to broiler diets up to 0.20 mg Cr/kg diet. A 49-day study was conducted to: 1) determine the safety of Cr Prop when supplemented at 2 and 10 times (×) the approved feeding level over the normal life span of broilers, and 2) determine the effects of supplementing Cr Prop on Cr concentrations of tissues consumed by humans. On day zero, 216 Ross 708 broilers were stratified by weight within sex and randomly assigned to treatments. Dietary treatments were 0 (control), 0.40, and 2.0 mg supplemental Cr/kg diet from Cr Prop. There were 6 replicate cages each of male and female broilers per treatment. At the end of the study, blood was collected for determination of plasma biochemical measurements and tissue samples were collected for Cr analysis. Supplementing 0.40 mg Cr/kg diet (2×) did not adversely affect broiler performance, mortality, plasma biochemical measurements or Cr concentrations in breast muscle, skin with adhering fat, or liver. Chromium propionate supplemented at 2.0 mg Cr/kg (10×) did not affect Cr concentrations in breast muscle or skin with adhering fat, but increased (P < 0.05) liver Cr concentrations. Supplementing Cr Prop at 10× the approved feeding level decreased feed intake and gain in male but not female broilers from days 21 to 49. Results of this study support the safety of Cr Prop in broiler diets, and indicate that Cr Prop supplementation to broiler diets at 2 or 10× the approved feeding level does not present a human health concern.", "pub_time": "2019"}
{"sha256": "0005b62c8efc93e17fbf2e336636f5256efe37ec1f16aefe434db1ea2ddcd3e2", "doi": "10.1063/1.5109498", "title": "3D-printing quality in relation to melt flow and fusion behavior of polymer materials ", "author": "Dietmar Auhl, Falk Rohnstock, Oliver Löschke, Konstanze Schäfer, Peng Wang, Manfred H. Wagner", "keyword": "", "abstract": " Full fusion and layer contact are essential for the mechanical, but also optical quality of 3D-printed parts. A comprehensive study on relations of 3D-printing quality to melt flow and fusion behavior is presented for a wide range of thermoplastic polymer materials. We investigated the influence of polymer structure and chain length as well as processing temperature, which largely determine material viscosity and surface tension. Furthermore, the influence of particle or layer dimensions is investigated. Comparisons of experimental and simulated data using well-established models and sets of parameters allow drawing valuable conclusions for optimizations of 3D-printing conditions and product quality. ", "pub_time": "2019"}
{"sha256": "35aad37222492defb1da5f96c69fd9da717e60b606ec955269d7fff5c0ff616c", "doi": "", "title": "砂生槐根际促生菌的筛选及干旱胁迫下对其种子萌发和幼苗生长的促生效应研究", "author": "王孝先", "keyword": "砂生槐，根际促生菌，干旱胁迫，促生效应", "abstract": "随着社会经济的发展，加上环境污染、能源枯竭等一系列问题的出现，严重危害了地球生态系统的平衡，全球经济也遭受了巨大的破坏。西藏高原是一个自然环境独特、社会经济发展状况迥异于其他地区的地方，脆弱的生态环境以及所处荒漠化区域严重影响到了藏区工农业生产和藏区人民的生活水平，给西藏自治区综合开发和经济发展构成了直接威胁。砂生槐作为高原主要建群种之一，具有固沙、保持水土的生态功能，并且饲用和药用价值可观。由于砂生槐分布的特殊地理环境，一年中遭受低温和大风的时间较长，还有放牧、人为砍伐、水灾和干旱等多种不利因素的影响，再加上砂生槐本身造林成活率低下，一直制约着雅鲁藏布江流域生态的恢复与发展。\n植物在生长过程中产生的植物根际促生菌（PGPR），包括生长调节剂（植物激素）、固氮菌、溶磷菌和生长素等物质。一方面直接影响着植物的新陈代谢，另一方面也提高了植物从土壤中吸收其他养分的适应能力，直接或间接地使植物更加容易吸收营养物质，防止流失，是一种新型的提高作物产量、缓解胁迫、保护环境的微生物肥料，因此如何筛选出具有高效促生能力的菌株至关重要。本试验以筛选具有良好促生作用的砂生槐植物根际促生菌为研究目标，在西藏农牧学院生物技术中心展开实验，探究筛选获得的根际促生菌的溶磷、固氮和产IAA能力，通过使用平板对峙法来测定菌株的拮抗作用，采用革兰氏染色探究菌株的生理生化特性。研究干旱胁迫下筛选菌株对砂生槐种子萌发和幼苗生长的影响，在模拟自然干旱条件下设立盆栽试验进一步验证菌株促生能力，探讨干旱胁迫下接种PGPR对砂生槐幼苗的影响。最终实验结果如下：\n（1）本研究从西藏米林县、朗县、加查县、林周县、白朗县、拉萨市、日喀则市、贡嘎县、扎囊县等地采集盛花期和结荚期砂生槐根际土壤进行微生物分离、纯化及促生性测试获得固氮菌株12株，解有机磷菌株10株，解无机磷菌株4株，其中有10株菌株产IAA。\n（2）通过采用半微量凯氏定氮法和钼锑抗比色法分别测定菌株氮含量和有效磷含量，测定结果显示：筛选得到的菌株氮含量在108~225μg/mL之间，其中菌株N24-2氮含量最高为225μg/mL，其次是菌株N23-3，氮含量为200μg/mL。14株溶磷菌中菌株SR21-的D/d比值最大为3.8，菌株SR15-1和SR10-6的D/d比值最小为2.0；解磷菌中有效磷含量最高的菌株是SR19-2，有效磷含量为96.13μg/mL，其次为SR19-1，为92.13μg/mL。有效磷含量最低的菌株为SR10-3，有效磷含量仅有33.25μg/mL，溶磷圈大小也较小，D/d比值为2.4。\n其中筛选得到的菌种中有10株菌株具有分泌IAA的能力，菌株SR26-3产IAA的量最高，为43.28mg/L，产IAA量最低的是菌株SR21-1，分泌IAA量为19.02mg/L。\n（3）菌株与病原菌的拮抗实验结果显示筛选所得的菌株N40-4和N22-5对小麦纹枯病原菌、小麦赤霉病原菌、小麦根腐病原菌、马铃薯干腐病原菌和玉米大斑病原菌均有拮抗作用，其中其中N21-1只对马铃薯干腐病原菌不产生拮抗作用，SR19-2只对小麦赤霉病原菌不产生拮抗作用，对其余四种病原菌均产良好的抑制效果；大多数菌株对小麦赤霉病原菌、小麦根腐病原菌和玉米大班病原菌有拮抗作用，相比较而言，菌株对小麦纹枯病原菌和马铃薯干腐病原菌的抑制整体来说相对较弱。\n（4）PGPR对砂生槐种子萌发和在PEG模拟干旱胁迫条件下的促生实验表明在种子萌发期间，接种菌悬液的情况下对砂生槐种子萌发影响较大，种子萌发期间接种固氮菌和溶磷菌时，除N35-2和SR22-3外，其余菌株均对砂生槐种子萌发有一定的促进作用，其中菌株N21-1和SR21-1对种子促生效果最好。在不同PEG浓度的影响下，通过对照CK1（无菌水条件）和CK2（有机磷对照培养液）的种子萌发以及各项指标综和分析，不同菌株的处理在不同PEG浓度梯度下对砂生槐种子萌发表现出不同的促进或抑制作用，其中SR21-1、SR26-3两个菌株综合评价最好，耐旱等级为1级，在模拟干旱条件下促进了砂生槐种子的萌发并显著增强了砂生槐的抗旱性。\n（5）通过菌株形态特征观察发现：两组菌株均呈白色，不透明，隆起度为凸起。其中SR21-1为椭圆形，齿状边缘，表面较为干燥；SR26-3为圆形，边缘完整，表面较为湿润。通过对菌株的细胞特征观察发现，SR21-1和SR26-3细胞形态均呈杆状，均不产生芽孢，且革兰氏染色均为阴性（G-）；菌株经16SrDNA分子鉴定初步结果显示：菌株SR21-1鉴定结果为曼格洛维杆菌；菌株SR26-3鉴定结果为普利茅斯沙雷氏菌。\n（6）自然干旱胁迫下在对砂生槐幼苗接种PGPR的盆栽实验结果表明，干旱胁迫下随着时间梯度的进行接种PGPR后的砂生槐幼苗体内脯氨酸和丙二醛含量均会随着不同的干旱时间而做出改变，均有增长的趋势，并且在接种促生菌后，叶绿素的含量较CK明显增加，表明接种植物根际促生菌能够促进叶绿素的合成，明显提高光合速率，促进砂生槐幼苗的生长。\n试验结果表明，最终筛选获得的SR26-3和SR21-1具有良好的耐干旱能力，可初步作为缓解砂生槐在干旱胁迫下生长的优良菌株，为后期砂生槐根际促生菌的筛选提供科学合理的理论依据。", "pub_time": "2020"}
{"sha256": "6b70b1ca9b9de6badb766b2283cd743a293b592377c5e8741551129c39b17a71", "doi": "", "title": "具有硅交联结构的高导离子杂化凝胶聚合物电解质的制备及性能研究", "author": "张德洒", "keyword": "凝胶聚合物电解质, 溶胶－凝胶法, 电化学性能, 热性能, 电致变色性能", "abstract": "凝胶聚合物电解质（GPEs）结合了固态聚合物电解质和液态电解质的优势，易于配置成所需尺寸和形状，具有制备轻巧、薄而小的电化学器件的潜力。本文选用溶胶-凝胶法制备具有硅氧烷结构的高导离子有机/无机杂化 GPEs，并研究了其性能。以均苯四甲酸二酐（PMDA）与聚丙二醇双（2-氨基丙基醚）（2-APPG）为原料，反应形成带端氨基的聚酰亚胺基预聚体，利用异氰酸酯丙基三甲氧基硅烷（ICS）与末端氨基反应引入甲氧基硅烷结构，通过适量的γ-缩水甘油醚氧基丙基三甲氧基硅烷（GLMO）与电解质体系中残留的酰胺酸反应，最后利用溶胶-凝胶法制备得到有机-无机杂化 APiG-x。在聚合物基体中，GLMO 添加的比例对杂化 APiG-x 的性能有显著影响。APiG-25 具有优异的热稳定性，在 280°C 的温度下无明显的分解，高离子电导率（1.62×10⁻³ S/cm）及良好的光学调制性能（CE 值为 198.9 cm²/C），以此电解质组装得到的电致变色器件（ECDs）具有良好的循环稳定性。\n在上述试验的基础上，为了得到无色透明的聚合物电解质，以进一步提高电致变色器件的光学调制性能，以异佛尔酮二异氰酸酯（IPDI）作为原料，在聚合物电解质结构中引入稳定的脲基结构。得到的聚合物基体水解缩合成膜后，在电解液中溶胀得到无色透明的杂化凝胶聚合物电解质 AlI-x。研究了 2-APPG 的分子量对杂化 AlI-x 的性能的影响。与其他 AlI-x 相比，AlI-50 具有最低的玻璃化转变温度（-57.54°C）、最高的溶胀率（477%）和离子电导率（1.43×10⁻³ S/cm）。设计得到的 AlI-x 电解质确为无色透明的聚合物电解质，并且以 AlI-50 为电解质制备成的电致变色器件具有良好的光学调制性能（着色效率 CE 值=278.6 cm²/C）。\n在杂化 AlI-x 的基础上，通过在聚合物主链结构中引入另一种由 ICS 与聚乙二醇单甲醚（MPEG）反应合成的前驱体，通过水解和缩合反应在聚合物主链中形成柔软支链结构。研究了两种前驱体的不同配比对具有硅氧烷结构的脲基改性 AM-x 的结构、热性能、电化学性能的影响，并进一步探讨了 AM-x 组装的 ECDs 的电致变色性能。采用傅立叶变换红外光谱测试（FTIR）和²⁹Si 核磁谱图对 AM-x 结构进行分析，证实了在聚合物主链中成功引入柔性支链。由差示扫描量热法（DSC）和电化学测试证实，引入支链结构确实降低了聚合物基体的玻璃化转变温度，增大了在电解液中溶胀率和离子电导率。同 APiG-25 和 AlI-50 相比，AM-9 具有最低的玻璃化转变温度（-58.57°C）、良好的热稳定性（315°C 之前无明显质量损失）、最高的溶胀率（507%）、最高的离子电导率（1.67×10⁻³ S/cm），制备成的电致变色器件具有最好的光学调制性能（CE 值=282.9 cm²/C）和良好的循环性能（550 次）。", "pub_time": "2021"}
{"sha256": "6b7903da1c7f8453f44d5c8460980f35278bb5938f630c0c9921c03b24aa4860", "doi": "", "title": "转录因子 DDIT3 的相分离及其影响乳腺癌细胞增殖和迁移能力的研究", "author": "张林", "keyword": "DDIT3, IDR, 液液相分离, 突变体, 抑癌因子 ", "abstract": "DDIT3 (DNA damage-inducible transcript 3)，也被称为CHOP (C/EBP homologous protein)，在内质网应激过程中促进细胞凋亡。通过对DDIT3的结构进行分析，发现其蛋白序列中有一段内在无序的低复杂序列（Intrinsically disordered region, IDR）。近年来的多项研究发现，许多带有IDR的蛋白能够通过该区域的相互作用而发生相分离，进而调控蛋白的各种生物学功能。因此，本论文的研究目的是鉴定DDIT3是否发生相分离，并通过相分离机制调控细胞的增殖与迁移。研究结果包括：\n（1）设计了四个DDIT3突变体，包括一个只含有转录激活域（TAD）的突变体DDIT3(34-124)、一个含有IDR的C端碱性亮氨酸拉链结构域（bZIP）突变体DDIT3(125-192)和两个突变了核定位信号的突变体DDIT3(4A)和DDIT3(3A)，并构建了野生型（WT）和这些突变体的原核和真核细胞表达载体。\n（2）在大肠杆菌表达和纯化了WT和各突变体的EGFP-DDIT3融合蛋白。在聚乙二醇作为拥挤剂的体外条件下，EGFP-DDIT3(WT)能够形成动态液滴，表明发生了相分离；DDIT3(125-192)，DDIT3(4A)和DDIT3(3A)虽然也能够进行相分离，但能力明显减弱；而DDIT3(34-124)失去了体外相分离的能力。\n（3）在HeLa和U2OS细胞中表达时，DDIT3(WT)能够在细胞核内形成对1,6-己二醇敏感的聚集点，从而鉴定了DDIT3在细胞核内也能够发生相分离。在各DDIT3突变体中，仅有DDIT3(125-192)能够在细胞内发生相分离。\n（4）在凝胶电泳迁移（EMSA）实验中，DDIT3(WT)及其突变体均显示与DR4基因启动子探针的结合能力，其中，DDIT3(125-192)显示出以多聚体形式与DR4启动子探针相结合。\n（5）在检测DDIT3对乳腺癌细胞影响的实验中，内源DDIT3的敲低促进了乳腺癌细胞增殖；在表达外源DDIT3时，DDIT3(WT)显示出对乳腺癌细胞最强的抑制活性，DDIT3(4A)的抑制癌细胞活性与WT相似，DDIT3(34-124)和DDIT3(3A)都显示出活性降低，而DDIT3(125-192)丧失了最多的抑制活性。在细胞划痕实验中，这些DDIT3(WT)和突变体对乳腺癌细胞迁移的抑制活性也显示相似的变化趋势。\n本论文的实验结果表明，DDIT3能够在体外及细胞内发生相分离。与以往报道的转录因子不同，DDIT3蛋白中负责相分离的IDRs不仅存在于TAD区域，还与其DNA结合区域有所重叠。缺失TAD或bZIP区域，均会影响DDIT3的抑癌活性。同时，我们首次鉴定了DDIT3是一个具有多个DNA结合位点的转录因子。\n本研究揭示了DDIT3蛋白能够发生相分离，这为解析DDIT3抑癌活性的分子机制提供了理论和实验基础。\n", "pub_time": "2022"}
{"sha256": "000b82068c71096c7605c2821f83ad786515cc380a1f7652f5822f7f77741fec", "doi": "", "title": "¹⁸F-FDG PET/CT 联合临床指标在初治多发性骨髓瘤中的预后价值", "author": "李俊龙", "keyword": "多发性骨髓瘤, 18F-FDG, PET/CT, 预后", "abstract": "目的 多发性骨髓瘤（multiple myeloma, MM）属于增殖性浆细胞肿瘤，患者预后差异显著。临床常用的判断预后的传统分期系统仅针对临床指标而在局限性。¹⁸F-FDG PET/CT 作为一种全面评估 MM 病情的影像学手段，能提供代谢层面的疾病信息。本研究旨在综合应用 ¹⁸F-FDG PET/CT 影像参数和临床指标，对未经治疗的新诊断 MM 患者的预后进行评估，以期获得更佳的预后评价指标。\n方法 回顾性收集 2014.08.01–2020.07.31 期间临床明确诊断为 MM、且未经治疗的患者 133 例，其中男性 77 例，女性 56 例，平均年龄 59.0±9.6 岁，所有患者均进行 ¹⁸F-FDG PET/CT 检查，且临床资料及随访资料完整，中位随访时间 22 月。记录患者无进展生存期（progression free survival, PFS）和总生存期（overall survival, OS）。利用 Mann-Whitney U 及 χ² 检验或 Fisher 精确检验分析 ¹⁸F-FDG PET/CT 参数间的差异，Cox 比例风险模型评估 ¹⁸F-FDG PET/CT、临床参数对 PFS 和 OS 的预测能力。按每个独立预测因子的积分法构建新预后预测系统（new prognostic prediction system, NPPS），Kaplan-Meier 估计 NPPS 对患者生存期的影响。比较 NPPS 与 ISS、修订的国际分期系统（revised-ISS, R-ISS）的预测效能。\n结果 在 133 例患者中，26 例进展或复发，53 例死亡，54 例无病生存。通过 χ²/U 检验得出，当以最大标准化摄取值（maximum standard uptake value, SUVmax）≥ 2.5 为分界点时，高 SUVmax 组的血清钙（sCa）、骨髓浆细胞浸润百分比（BMPC%）较低水平升高（p < 0.05）；SUVmax ≥ 5.3 的男性比例大于女性，β₂ 微球蛋白（β2-microglobulin, β2-MG）、血肌酐（sCr）、白蛋白（sAlb）、C 反应蛋白（creative protein, CRP）、ISS 及 R-ISS 分期水平有升高趋势。以局灶性病灶数（focal lesions, Fls）以3个分组，组间的sCa、血清游离轻链比（sFLC比）、BMPC%、R-ISS分期出现统计学差异，FIs≥10时，高水平组sCr、sCa值、DSS（Durie-salmon staging）分期更高，且更易出现髓外病灶（extremely malignant disease, EMD）。以梅奥骨髓瘤分层及风险调整治疗分层系统（Mayo Stratification of Myeloma And Risk-adapted Therapy, mSMART）3.0确立的高危患者（n=62）中，Kaplan-Meier显示“双打击”与“非双打击”组间OS（24.0 vs 48.0月，χ²=20.3，p=0.023）有显著差异。生存分析显示¹⁸F-FDG PET/CT阳性组的生存期明显差于阴性组。Cox多因素分析显示SUVmax≥5.3、受累与非受累血清游离轻链（serum free-light chain, sFLC）比＞100、EMD存在、高sCa是PFS的独立预测因子（p＜0.05）；SUVmax≥5.3、EMD存在、sFLC比＞100是OS的独立危险因素（p＜0.05）。ISS分期I期与II期、R-ISS分期II期与III期患者间OS无统计学差异（χ²分别为0.705、3.184，p＞0.05）；而本研究中利用上述独立因素构建NPPS后，能对MM的总生存期进行新的分期，从而对患者的OS进行更好地区分（χ²分别为17.344 [ISS I期vs II期]、29.966 [R-ISS II期vs III期]，p＜0.05）。\n结论：本研究结果显示，基于 ¹⁸F-FDG PET/CT（阳性或阴性、SUVmax 和 EMD）及临床指标（sFLC 比、sCa）能够很好地预测 MM 患者的 OS 和 PFS。由此构建的新预后预测系统（NPPS）比传统分期（ISS 和 R-ISS）更有效。以 mSMART 3.0 将骨髓瘤患者划分为高危组后，若伴有任意两个高危细胞遗传学异常的“双打击”标记“非双打击”组预后不良。此外，¹⁸F-FDG PET/CT 的影像学参数与临床指标关系密切，高 SUVmax、FIs 与较高的 sCa、sCr、CRP、sβ2-MG 以及髓外病灶的出现有一定关联，且与较晚的临床分期有关。", "pub_time": "2022"}
{"sha256": "a0fcd696aa5fb4cdbc2e4425caa38e696ffb43ab8ee876a0582a4f55582092bd", "doi": "", "title": "大口黑鲈转食过程中肝脏转录组与肠道微生物研究", "author": "何阔", "keyword": "大口黑鲈, 转食, 转录组, 肠道微生物, 16S rDNA, 消化酶, 肠道组织学观察 ", "abstract": "近年来，大口黑鲈逐渐成为中国最受欢迎的名优养殖品种之一，已经成为我国“第五家鱼”。转食是大口黑鲈养殖过程中最重要的生产环节，但其仔稚鱼转食成活率不稳定，死亡率高，一直制约着产业的发展。本研究利用第二代测序技术，对大口黑鲈转食三个阶段（转食前、中、后：pre，mid，post-weaning stages）肝脏转录组和肠道微生物进行研究以揭示大口黑鲈在转食过程中的肝脏代谢和肠道菌群的动态变化特征；同时通过消化酶活活性来探讨其转食过程中消化能力的大小及变化。主要结果如下：\n（1）对转食三个时期肝脏、肠道中三个重要消化酶（胰蛋白酶、脂肪酶、淀粉酶）检测发现：肠道中三种消化酶在转食中期均出现显著下降（p<0.5）；肝脏中淀粉在转食三个时期呈下降趋势，而在肝脏中未检测出脂肪酶和胰蛋白酶。随着转食进程的推进，大口黑鲈前肠道绒毛高度、宽度、肠壁厚度以及吸收面积在转食后显著高于转食前、中期；而肠道在转食中期肠壁厚度最薄和吸收面积最小。\n（2）通过对三个转食阶段两两之间进行差异表达基因分析，相较于其他两个时期，肝脏中在转食前有156个基因表达较高、260个表达较低；在转食中有60个基因表达较高、20个表达较低；在转食后有206个基因表达较高、165个表达较低。转食前高表达基因富集在胆固醇代谢、维生素消化吸收、氨基酸的生物合成和代谢等通路；转食前低表达基因富集在不饱和脂肪酸的生物合成、PPAR信号通路、脂肪消化吸收等通路。转食中高表达基因富集在环境信息处理、蛋白质消化吸收、运输和分解代谢等通路；转食中低表达基因富集在补体和凝血级联、血小板活化、抗坏血酸和新陈代谢等通路。转食后期高表达基因富集在PPAR信号通路、不饱和脂肪酸的生物合成、脂肪酸代谢、碳代谢等通路；转食后期低表达基因富集在氨基酸代谢、氨基酸的生物合成、胆汁分泌等代谢通路。\n（3）三个转食阶段肠道菌群主要分布在厚壁菌门、软壁菌门、梭杆菌门、拟杆菌门、放线菌门、变形菌门和蓝藻菌门。其中变形菌门和厚壁菌门变化最为显著，变形菌门丰度从转食前的56.32%下降到转食中、后阶段的28.91%、16.84%，而厚壁菌门丰度从25.29%上升到60.70%、62.81%。在转食中后期变形菌门中邻单胞菌属、鞘氨醇单胞菌属、不动杆菌属和寡养单胞菌属的丰度下降较为明显，而厚壁菌门中梭菌属丰度增长最为明显。\n总体而言，本研究揭示了大口黑鲈转食过程中肝脏转录组、肠道微生物及肠道消化酶的动态变化特征，为今后大口黑鲈转食研究提供一定的依据和参考。", "pub_time": "2020"}
{"sha256": "35dffb0877e0fa904b55800bfddc851abc3740f545c04aecb07b1a92e80f3ec1", "doi": "", "title": "过共晶 Al-14wt%Si 合金裂纹扩展行为研究", "author": "田源", "keyword": "过共晶铝硅合金, 裂纹扩展, 原位观察, 断口形貌, 热处理 ", "abstract": "到目前为止，科学工作者们对于过共晶Al-Si合金断裂机制的研究都是对于宏观表征的研究，对于过共晶Al-Si合金断裂过程中裂纹扩展机制的研究较少。\n本文针对过共晶铝硅合金裂纹萌生及扩展过程不清楚的问题，以Al-14wt%Si合金为研究对象，通过使用带有拉伸功能的高温激光共聚焦扫描显微镜，原位观察了裂纹的扩展过程，研究了裂纹的萌生位置及扩展路径、计算了裂纹在不同相中的扩展速率以及分析不同形貌硅相对裂纹扩展行为的影响规律。\n实验发现，裂纹首先在大尺寸硅相表面萌生、裂纹在初生硅内存在呈阶梯式扩展的现象。明确了裂纹萌生与扩展过程和硅相尺寸及形貌之间的对应关系。\n揭示了硅相尺寸越大，裂纹越容易在硅相表面萌生，硅相尺寸越小，裂纹萌生的方式逐渐向硅相与基体界面开裂转变；硅相内裂纹以直线方式扩展为主，以阶梯式及分叉方式扩展为辅；硅相开裂后裂纹首先选择硅相与基体界面为扩展路径，向硅相尖角处扩展，而后进入基体，其次直接进入基体，向就近的硅相扩展；硅相尺寸是导致过共晶铝硅合金断裂的主要因素、形貌影响较小的规律。\n研究表明，裂纹在硅相内直线扩展时，其扩展速率高达200~606μm/s，呈阶梯式扩展时扩展速率会降低90%。裂纹沿硅相界面最快扩展速率为4.97μm/s，在α（Al）基体内的扩展速率只有0.98μm/s。", "pub_time": "2021"}
{"sha256": "a12a233c920da463f0f3ae43116ed6c6a592406ae3caf80bd5f46e563ce1f9e6", "doi": "", "title": "气候变化背景下黄河流域植被变化成因及未来预估", "author": "赵倩倩", "keyword": "黄河流域, 植被变化, 气候变化, 人类活动, CＭIP６, 预估", "abstract": "全球气候变暖已成事实，这对人类社会、经济及生态环境产生重要影响。作为陆地生态系统中最重要的组成部分，植被在改善生态环境、减少水土流失等方面发挥巨大作用，但随着我国人口和经济的快速增长，人类活动可以直接或间接影响植被覆盖，加之气候变化的区域差异性，使植被覆盖变化十分复杂。深入研究植被覆盖的时空变化特征并探究其驱动因素对于制定生态文明建设的政策具有重要意义。\n黄河流域大部分位于干旱半干旱区，对气候变化十分敏感，也是人类活动最剧烈的地区之一。近年来，随着气候呈现出暖干化的趋势和“退耕还林还草”政策的实施，使整个流域植被覆盖发生了显著变化。2019年9月18日，习近平总书记在郑州召开“黄河流域生态保护和高质量发展”座谈会，黄河流域生态保护和高质量发展上升为国家战略。因此，研究气候变化背景下黄河流域植被变化及其成因，并基于未来气候变化条件，准确预测未来植被动态变化特征对了解黄河流域生态系统现状和未来植被变化特点具有重要意义。本文基于归一化植被指数（Normalized Difference Vegetation Index, NDVI）、气温、降水、scPDSI数据和土地利用数据，运用线性趋势、相关性分析、多元回归和残差分析等方法，从不同时空尺度分析近20年黄河流域植被变化与气候变化特征，探究NDVI变化与驱动因素之间的关系，评估气候和人类活动对植被变化的相应贡献；最后，通过历史气象和植被数据资料构建植被预测模型，预测2021-2050年在SSP2-4.5和SSP5-8.5两种情景下的植被动态变化特征。主要结论如下：\n(1) 2001-2020年黄河流域及子流域NDVI呈上升趋势且趋势基本一致，其中黄河中游NDVI增长速率（约为0.05/10a）高于整个流域（约为0.03/10a），而黄河上游增长趋势（约为0.02/10a）相对较小。夏季和生长季NDVI分别以0.06/10a和0.05/10a的速率呈明显波动上升趋势，而春季NDVI的线性趋势相对较小，为0.03/10a。空间尺度上，黄河流域植被指数总体呈现东南高西北低的分布特征。从NDVI变化趋势及显著性看，近20年黄河流域NDVI整体呈增加的趋势，较显著增加和显著增加区域占流域总面积的79.85%，显著减少主要集中在城市集中发展区。\n(2) 2001-2020年黄河流域年平均气温以0.12℃/10a的速率呈显著上升趋势，各子流域的升温速率排序为黄河下游＞黄河上游＞黄河中游。四个季节均有增温趋势，其中春季增温幅度最大。空间上，黄河下游等区域增温速率最大，而在陕西中部等区域，增温速率较小。黄河流域年降水量以24.63mm/10a的速率呈增加趋势，其中黄河上游增加趋势最快，而黄河下游增加趋势最慢。各季节降水量均呈增加趋势，生长季降水量增加最快；空间上，黄河流域降水量变化趋势存在较大的空间异质性。黄河流域年平均scPDSI以1.12/10a的速率呈增加趋势，其中黄河上游的增加速率最快，而黄河下游的增加速率最慢。季节尺度上，各个季节均呈增加趋势，其中夏季增加速率最快。空间上，scPDSI在四川省、青海省和甘肃省西部等区域以超过0.15/a速率呈增加趋势，而在黄河下游，scPDSI呈下降趋势，其值低于-0.02/a。\n(3) 黄河流域NDVI与气温、降水和scPDSI在大部分区域均呈正相关，且植被变化受降水和scPDSI两者的影响较大。在黄河上游，NDVI与降水和scPDSI的关系最为密切，其对NDVI变化趋势的贡献分别达到57.76%和67.24%；温度与NDVI的相关性在黄河下游最高，对其变化趋势的贡献达30.25%。季节尺度上，春季，NDVI与气温和scPDSI的相关性最高，而在夏季NDVI与降水量的相关性最高。近20年气候变化和人类活动对黄河流域NDVI变化的影响分别是0.76×10-3/a和0.27×10-2/a，相对贡献率分别为22%和78%。2000-2020年黄河流域土地利用变化较大，主要表现为草地与耕地、林地、未利用地之间的相互转换以及建筑用地的进一步扩张。可见，人类活动对黄河流域的植被变化有较大的影响。\n(4) 2021-2050年黄河流域年均气温和季节气温在SSP2-4.5和SSP5-8.5情景下均呈增加趋势且SSP5-8.5情景下增加幅度更大。季节尺度上，夏季气温增幅最大，春季增幅最小；年际降水量在SSP5-8.5情景下的线性趋势低于SSP2-4.5情景。季节尺度上，秋季降水增幅最大，其次是生长季。不同情景下，气温和降水量的趋势分布在空间上存在较大的差异性。未来黄河流域植被覆盖普遍增加，在年际、春季、秋季和生长季，SSP5-8.5情景下的植被覆盖增加程度大于SSP2-4.5情景，而夏季时，SSP2-4.5情景下植被指数上升速率高于SSP5-8.5情景。未来中游北部植被覆盖呈上升趋势，而在陕西中部区域，植被变率为负值，表明植被在退化。", "pub_time": "2022"}
{"sha256": "a12f35c122cb1027a5a1d8e7b9fd7e807194e6a340031fad6ca2e84057771b27", "doi": "", "title": "基于网络评论的情感分析与用户行为研究", "author": "李明烛", "keyword": "机器学习, 特征提取, 循环神经网络, 卷积神经网络, 自注意力机制 ", "abstract": "随着电子商务行业的飞速发展，消费者越来越注重商品质量和购物体验，为方便商家和物流公司听取消费者意见，电商平台通常会具备商品评论功能。商品评论包含了消费者对商品质量，物流效率和平台的使用情况等多方面的评价。商家、物流公司和电商平台可以根据商品评论规划发展策略，提升服务质量。\n由于文本数据自身的抽象性和复杂性加之商品评论口语化和网络化的特点，使基于情感词典按规则计算的方式或采用机器学习实现商品评论情感分析的效果都不甚理想。为提升模型的情感倾向识别能力，本文在卷积神经网络（CNNs）、循环神经网络（RNNs）和自注意力机制的基础上提出 TextInception 卷积网络和两种融合模型：\n（1）本文在文本卷积神经网络（TextCNN）的基础上结合图像处理领域的 Inception 模型结构的设计思想，提出 TextInception 文本卷积模型。\n（2）基于 RNNs、多头自注意力机制（Multi-Self-Attention）、句嵌入自注意力机制和 TextInception 四种网络结构设计了 SA-BiLSTM-TextInception 融合模型。Multi-Self-Attention 用来增强各个输入节点的上下文信息，通过 SA-BiLSTM 和 TextInception 两种不同的编码方式实现特征二次提取并分别输出句向量，最后由 Add 层融合两种句向量后作为 SA-BiLSTM-TextInception 的输出结果。\n（3）本文基于预训练神经网络语言模型（ELMo）的迁移学习方法提出 SA-ELMo-TextInception 融合模型。通过 ELMo 生产词向量，能显著增强模型特征提取能力，使模型理解更复杂的句法和语义信息。\n将上述两种融合模型分别在预处理后的商品评论数据训练后分析实验结果，验证 ELMo 特征提取方式和焦点损失函数（Focal Loss）对模型分类能力的提升。", "pub_time": "2021"}
{"sha256": "a10fc17da14d6ef3b91479ac2f7889c68695af35631b8a74d7fdf0cad9cc5815", "doi": "", "title": "污泥-薰衣草生物炭及绿色合成材料对亚甲基蓝吸附性能研究", "author": "赵居芳", "keyword": "生物炭, 绿色合成, 纳米零价铁, 吸附, 亚甲基蓝 ", "abstract": "近年来，伴随着我国染料行业和工业化迅速发展的浪潮，在自然环境中产生了大量的污泥并且有一大部分的染料在生产和使用过程中直接或间接地释放到环境中，其中多数染料不稳定，排放到水中难以自然降解。去除废水中染料的方法较多，吸附法因具有简单、高效、廉价等优势，因而被广泛应用。污泥中含有多种复杂成分且产量广泛，对其进行资源化管理是保护环境的大势所趋；薰衣草中含有羟基、氨基等多种有机基团，是一种优良吸附剂且以薰衣草作为吸附材料去除染料亚甲基蓝(MB)的研究较少。本文利用污水处理厂的污泥和薰衣草混合制备生物炭，薰衣草提取液合成生物炭负载纳米零价铁(LA-nZVI/BC)作为生物炭材料，其中纳米零价铁的英文名称为(Nano zero valent iron)，简写(nZVI),用吸附法研究在水溶液中混合生物炭和绿色合成生物炭对MB的吸附特性。主要结论如下：\n（1）通过扫描电镜(SEM)可以观察到干污泥呈块状结构，其表面较平整光滑。高温热解后，生物炭表面块状结构减少，且孔隙散乱分布，表面粗糙，有结团现象，孔隙度大于干污泥，比表面积显著增大，此现象与比表面积与孔径分析仪(BET)测试结果一致。通过傅立叶红外光谱(FTIR)发现：污泥生物炭(SL)含有较丰富的含氧官能团和芳香化结构，为吸附MB提供了有利条件。\n（2）按照相同质量对污泥、薰衣草进行热解、按照3:2和1:1的质量比将污泥与薰衣草混合后再进行热解制备生物炭，热解温度500℃，热解时间180min，在此条件下热解制得四种比例的生物炭分别为污泥生物炭(SL)、薰衣草生物炭(LA)、污泥和薰衣草混合质量比3:2生物炭(SL-LA40%)、污泥和薰衣草混合质量比1:1生物炭(SL-LA50%)。通过吸附实验，得出对MB吸附的最佳条件：溶液初始pH为8，投加量为0.05g，吸附平衡时间为360min，初始浓度50mg/L，在此条件下实验得出对MB的吸附量由大到小依次为LA＞SL-LA50%＞SL-LA40%＞SL，在MB初始浓度为20~500mg/L的范围内，对MB的吸附量随初始浓度的增大而增大，LA在30℃下对MB的最大吸附量为144.50mg/g，SL在30℃下对MB的最大吸附量为114.29mg/g。准二级动力学和Langmuir吸附等温线模型可以较好地描述该吸附过程。SL、SL-LA40%、SL-LA50%、LA吸附速率常数在投加量为0.05g、溶液初始pH为8，MB水溶液初始浓度为50mg/L时，分别为：0.00471、0.00694、0.00723、0.00365 g/(mg·min)⁻¹。\n（3）动力学模型和等温线模型表明，四种比例的生物炭对MB的吸附主要是单分子层吸附，整个吸附过程是吸热反应，升温对吸附反应有促进作用，且以化学吸附为主。\n（4）四种比例中，SL对MB的吸附性能最低，因此对污泥生物炭进行绿色合成负载纳米零价铁来提高它的吸附性能。选取薰衣草萃取液浓度、固液比、FeSO₄·7H₂O浓度为影响因素，以MB吸附容量为实验指标，通过正交实验，得到固液比(A)＞薰衣草萃取液浓度(B) > FeSO₄·7H₂O(C)浓度。最佳条件为：A₃B₁C₁，固液比为1:200 g/mL，薰衣草萃取液浓度为100 g/L，FeSO₄·7H₂O浓度0.1 mol/L。通过绿色合成对水溶液中MB的吸附性能和吸附机理进行研究。结果表明，与SL相比，LA-nZVI/BC对MB的吸附性能明显提高。在中性或弱碱性条件下，投加0.05 g绿色合成材料，在30 ℃下震荡360 min，在MB初始浓度20–500 mg/L范围内，MB初始浓度越大，吸附量越大，LA-nZVI/BC对MB的最大吸附量为205.34 mg/g，吸附动力学符合准二级动力学模型，Langmuir吸附等温线模型能较好地描述该吸附过程，吸附机理与静电相互作用、氢键、配位络合作用、π-π、离子交换等有关。\n（5）对绿色合成材料做了 SEM、FTIR、XPS(X 射线光电子能谱)表征，结果表明：薰衣草提取液能将二价铁离子还原成纳米零价铁颗粒，在生物炭表面形成球形颗粒，均匀地附着在生物炭表面形成 LA-nZVI/BC 材料，薰衣草提取液中的有机物，如黄铜、多糖、多酚等有机物附着在 LA-nZVI/BC 的表面，提高对材料的稳定性和 MB 的吸附性。", "pub_time": "2022"}
{"sha256": "6b6cdae00fbaa5d42dccb29a65cc31c96f1145735c5d8317763697e69c38134c", "doi": "", "title": "复杂环境中非对称半潜式起重平台及系泊系统耦合动力响应特性研究", "author": "刘传艺", "keyword": "非对称半潜式起重平台, 耦合动力响应, 系泊系统特性, 安全校核 ", "abstract": "非对称半潜式起重平台拥有超强的吊装能力，它的结构比较新颖，不同于传统的半潜式平台，具有非对称的下体结构，在平台主体的右侧配备有重型起重机，载有起重机的一侧的浮体尺寸明显大于另外一侧。非对称的结构会使此平台在系泊系统的水动力及运动响应不同于常规的半潜式起重平台，所以研究其水动力及运动响应具有重要的意义。\n本文采用势流理论并进行相关的数值计算，对一新型非对称的半潜式起重平台及系泊系统的耦合工作响应进行研究，具体相关工作为：\n（1）建立三维水动力模型，根据三维势流理论对非对称半潜式起重平台进行水动力性能分析，获得非对称半潜式起重平台的运动响应幅值 RAO、一阶波浪力、二阶波浪力、附加质量等计算结果，分析非对称结构对平台水动力性能的影响。结果显示：平台的横荡、横摇、艏摇运动受受峰向值的影响较大。横荡运动的 90°和-90°的 RAO 数值存在一定偏差，90°的峰值为 1.308m/m，-90°的峰值为 1.302m/m。横荡 90°浪向下的最大值为 0.700°/m，-90°的浪向下的最大值为 0.657°/m。船舶运动主要出现在斜浪 60°和-60°下，分别为 0.287°/m、0.271°/m。\n（2）本文对非对称半潜式起重平台系泊系统特性展开研究，对系泊系统进行布置，研究不同缆绳数目、系泊缆悬链松弛度等系泊系统参数，计算分析这些参数对平台运动及系泊受力情况的影响。结果发现：在系泊缆数目参数分析中，比较了 8 根和 12 根系泊缆下的平台运动和系泊缆张力情况，发现在同时满足规范要求的情况下，8 根系泊缆的经济性更好；在研究系泊缆悬链松弛度时，选择了 5 种不同的松弛度的系泊缆，发现悬链松弛度为 7.5 的系泊缆运动性能和经济性最好。\n（3）对非对称半潜式起重平台及系泊进行时长3小时的时域短期预报，得到不同工况下的运动响应时历曲线，系泊张力统计值，分析总结不同方向海况下不同缆绳的分布规律以及运动响应的统计特性，并对三种工况下系泊系统进行安全校核。结果发现：当有义波高为6m，风浪流入射方向为-180°时，非对称半潜式起重平台系泊缆中受力最大的是8#缆绳，系泊张力为8.29×10⁶N，安全系数为5.33；当有义波高为2.5m，风浪流入射方向为-90°时，非对称半潜式起重平台系泊缆中受力最大的是4#缆绳，系泊张力为3.75×10⁶N，安全系数为11.77，这两种工况下的系泊系统都可以满足规范要求。当有义波高为13.5m时，风浪流入射方向为180°，8#缆绳存在最大张力3.4671×10⁷N，安全系数为1.28，小于规范要求的安全系数1.67，此极限海况下的系泊系统已无法满足规范要求，但没有超过破断强度，尚可以处于生存状态。所以总体来说三种工况的系泊系统基本可以满足要求。", "pub_time": "2020"}
{"sha256": "6bb400093d478c4d66e5355fa9687f3de770fb54ad3b1a49acf6dac8e7883b9d", "doi": "", "title": "靶向乳腺癌高亲和力融合肽探针诊疗一体化体系的构建", "author": "姚兰琳", "keyword": "⁶⁸Ga-DOTA-RGD-ATWLPPR, 乳腺癌, RGD, ATWLPPR，PET 显像", "abstract": "目的：已有相关文献证实 Neuropilin-1（NRP-1）和整合素 αvβ3 受体在乳腺癌组织中均有表达。我们将 Arg-Gly-Asp（RGD）和 Ala-Thr-Trp-Leu-Pro-Pro-Arg（ATWLPPR）肽团合成二聚体 RGD-ATWLPPR，通过标记放射性核素 ⁶⁸Ga，来靶向 αvβ3 受体和 NRP-1 受体。研究 ⁶⁸Ga-DOTA-RGD-ATWLPPR 对乳腺癌显像和诊断的价值，并对其作为乳腺癌靶向示踪剂进行生物学评价。\n方法：①通过 DOTA 上的羧基与融合肽 RGD-ATWLPPR 对应的游离氨基反应，所得到的前体被进一步纯化。通过 ⁶⁸Ga 进行放射性标记，测定标记物的放射化学纯度以及药物体外的稳定性。②在人乳腺癌 MCF7 荷瘤裸鼠体内进行小动物 PET/CT 显像，并与 ⁶⁸Ga-DOTA-RGD、⁶⁸Ga-DOTA-ATWLPPR 两种单肽显像剂在 PET/CT 研究中进行对比。③研究该药物在 MCF7 荷瘤裸鼠体内的药代动力学，注射 ⁶⁸Ga-DOTA-RGD-ATWLPPR 后 5、15、30 和 60 分钟立即进行生物分布研究。④MCF7 肿瘤组织中 αvβ3 和 NRP-1 的表达水平检测。\n结果：⁶⁸Ga-DOTA-RGD-ATWLPPR 在 25 分钟内标记，衰减校正产率 86.1±4.8%（n=3），比活性为 59.1-73.9 GBq/μmol，体外表现出较高的稳定性。静态 PET/CT 成像研究中，MCF7 荷瘤裸鼠肿瘤在注射 ⁶⁸Ga-DOTA-RGD-ATWLPPR 后 30 分钟可清晰显示，并表现出比 ⁶⁸Ga-DOTA-RGD 或 ⁶⁸Ga-DOTA-ATWLPPR 单肽显像剂更高的摄取，绘制感兴趣区域（ROI）以量化肿瘤对不同显像剂的摄取能力。MCF7 对 ⁶⁸Ga-DOTA-RGD-ATWLPPR（4.94±1.05 %ID/g）的摄取高于⁶⁸Ga-DOTA-RGD（3.69±0.72%ID/g，P<0.05）和 ⁶⁸Ga-DOTA-ATWLPPR（2.59±0.56%ID/g，P<0.001），说明 ⁶⁸Ga-DOTA-RGD-ATWLPPR 具有更高的靶向亲和力。用 Arg-Gly-Asp（RGD）和 Ala-Thr-Trp-Leu-Pro-Pro-Arg（ATWLPPR）冷肽进行阻断研究显示了 ⁶⁸Ga-DOTA-RGD-ATWLPPR 高特异性，PET/CT 延迟显像中，MCF7 荷瘤裸鼠肿瘤 60 分钟后对 ⁶⁸Ga-DOTA-RGD-ATWLPPR 的摄取值仍然较高，能清晰的反应肿瘤病灶，T/N 比值高于 ⁶⁸Ga-DOTA-RGD、⁶⁸Ga-DOTA-ATWLPPR 对照组。生物分布显示 ⁶⁸Ga-DOTA-RGD-ATWLPPR 示踪剂主要通过肾脏清除。\n结论：⁶⁸Ga-DOTA-RGD-ATWLPPR 是一种 αvβ3 和 Neuropilin-1 双受体靶向示踪剂，与单体 ⁶⁸Ga-DOTA-RGD 和 ⁶⁸Ga-DOTA-ATWLPPR 相比，具有更高的结合亲和力、靶向效率和更长的肿瘤保留时间，提示其具有应用于乳腺癌成像诊断的前景，为进一步的诊疗一体化研究建立基础。", "pub_time": "2021"}
{"sha256": "6bb49d396b8e164257d7606fdb75a9801c23bdb81fd1950acd69be6cf42daa6a", "doi": "10.26434/chemrxiv-2024-3l5bg-v2", "title": "Cationic Polaron Delocalization in Porphyrin Nanoribbons", "author": "Sebastian M. Kopp, Jie-Ren Deng, Ashley J. Redman, Henrik Gotfredsen, Robert M. J. Jacobs, Harry L. Anderson, Christiane R. Timmel", "keyword": "porphyrin tapes, delocalization, polarons, electron paramagnetic resonance, spectroelectrochemistry, organic polymers, nanoribbons", "abstract": "Long-range delocalization of unpaired electrons in organic p-conjugated oligomers is an important requirement to achieve high charge carrier mobilities in molecular transistors. We have investigated the polaron delocalization in the radical cations of a series of b,meso,b-edge-fused porphyrin oligomers consisting of up to 18 porphyrin units by a combination of cw-EPR, 1 H and 14N ENDOR, HYSCORE and vis-NIR-MIR spectroscopy, supported by DFT simulations. The results demonstrate coherent delocalization of the radical cation over more than ten porphyrin units, which corresponds to an effective coherence length >8.5 nm. We discovered a remarkably non-uniform distribution of the radical spin density and an increase in phase memory time with increasing delocalization length (up to Tm ≈ 4 µs at 50 K). This study opens new avenues towards the design of molecular electronic and spintronic materials.", "pub_time": "2024"}
{"sha256": "d6b16519dda796013bcd1f4e9c3aee74b0ec13d8db0dbe96db9bc3449a2f847f", "doi": "10.26434/chemrxiv-2024-mx605", "title": "Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution of Tetra-substituted Morpholinone and Benzoxazinone Lactols", "author": "Haoxiang Zhu, Alejandro Manchado, Abdikani Omar Farah, Aidan P. McKay, David B. Cordes, Paul Ha-Yeon Cheong, Kevin Kasten, Andrew D. Smith", "keyword": "", "abstract": "The development of methods to allow the selective acylative dynamic kinetic resolution (DKR) of tetra-substituted lactols is a recognised synthetic challenge. In this manuscript, a highly enantioselective isothiourea-catalysed acylative DKR of tetra substituted morpholinone and benzoxazinone-derived lactols is reported. The scope and limitations of this methodology have been developed, with high enantioselectivity and good to excellent yields (up to 89%, 99:1 er) observed across a broad range of substrate derivatives incorporating substitution at N(4) and C(2), di- and spirocyclic substitution at C(5)- and C(6)-position, as well as benzannulation (>35 examples in total). The DKR process is amenable to scale-up on a 1 g laboratory scale. The factors leading to high selectivity in this DKR process have been probed through computation, with an N-C=O•••isothiouronium interaction identified as key to producing ester products in highly enantioenriched form. ", "pub_time": "2024"}
{"sha256": "368e84d45f1177d306dcfa731c0a26c6925ec44c9ea0d5e9c7473accadff7bd4", "doi": "", "title": "Organomagnesium crown ethers and their binding affinities with Li⁺, Na⁺, K⁺, Be²⁺, Mg²⁺, and Ca²⁺ ions - A theoretical study", "author": "Krishnan Thirumoorthy, Uday Kumar Padidela, Pothiappan Vairaprakash, Venkatesan S. Thimmakondu", "keyword": "organomagnesium crowns, host-guest molecules, alkali metal ions, alkaline earth metal ions, binding energies, Be²⁺ encapsulation", "abstract": " Novel organomagnesium crown ether molecules have been computationally char acterized for the rst time using density functional theory (DFT). Monomer units of MgC6 have been used as building blocks. The potential energy surface of the par ent elemental composition, MgC6H2, has been extensively explored using both DFT and coupled-cluster methods. It is concluded that the seven-membered ring isomer, 1-magnesacyclohept-4-en-2,6-diyne, is the thermodynamically most stable molecule at all levels. Thus, the latter has been used as the building block for organomagnesium crown ethers. Both alkali (Li+, Na+, and K+) and alkaline-earth (Be2+, Mg2+, and Ca2+) metal ions selective complexes have been theoretically identi ed. Binding ener gies ( E at 0 K) and thermally corrected Gibbs free energies ( G at 298.15 K) have been computed for these metal ions with MgC6-9-crown-3 and MgC6-12-crown-4 to gauge their binding a nities", "pub_time": "2021"}
{"sha256": "a12e91df12ceab22479624e482037bd2c18828371d6f2bf2d606250ad1a0378e", "doi": "", "title": "Does φ-Aromaticity exist in prismatic {Bi6}-based clusters? ", "author": "Dariusz W. Szczepanik1* and Miquel Solà2*", "keyword": "", "abstract": "", "pub_time": "2023"}
{"sha256": "0020fbcd510b5794fa7fb1aebb1fad7ae04ce312f0d141c3cafda10478ea3dbc", "doi": "", "title": "Effect of Bimetallic Doping in Cobalt Titanate for Methane Reforming", "author": "Disha Jain", "keyword": "", "abstract": "Unlike conventional supported bimetallic Ni catalysts, where Ni forms alloy with other metal, this study focuses on the incorporation of Ni and Pt in the lattice of the perovskite oxide. Perovskites offer high thermal stability and their properties can be tailored easily. In this study, the ionic substitution of Ni and Pt in CoTiO₃ was done by sonochemical method. The catalytic activity of the monometallic Ni and Pt samples were compared bimetallic catalysts towards SRM. The reducibility of the synthesized samples was examined by H₂ TPR and the appearance of multiple features mark the existence of complex interaction between metal ions and the support. The catalytic activity and stability towards steam (SRM) and dry reforming of methane (DRM) was studied over bimetallic Ni-Pt catalyst. A comprehensive reaction mechanism was proposed over bimetallic Ni-Pt-CoTiO₃ for SRM and DRM, with insights from ex situ and in situ characterization to understand the catalyst behavior.\n\n\n\n\n\n\n\n\n ", "pub_time": ""}
{"sha256": "d6df44764ed7cd8c8a0ff979345e407e84a50add602692b0504b7062cc0a37dc", "doi": "10.26434/chemrxiv-2023-g3lmq-v3", "title": "A guidebook for sustainability in laboratories", "author": "T. Freese, R. Kat, S. D. Lanooij, T. C. Böllersen, C. M. De Roo, N. Elzinga, M. Beatty, B. Setz, R. R. Weber, I. Malta, T. B. Gandek, P. Fodran, R. Pollice, M. M. Lerch", "keyword": "", "abstract": "", "pub_time": "2024"}
{"sha256": "a0f3d61a810d03c7e0ca3ac63f9f2270585fc25f42c77acd59ce58fbdf29fe78", "doi": "", "title": "Mechanochemistry of Spiropyran Under Internal Stresses of a Glassy Polymer", "author": "Richard Janissen, Georgy A. Filonenko", "keyword": "mechanophores, residual stress, polymers, polymeric glass, stress imaging", "abstract": "Mechanophores are powerful molecular tools used in polymers to track bond rupture and characterize mechanical damage. The majority of mechanophores are known to respond to external stresses and in this study we report the first precedent of a mechanochemical response to internal, residual stresses that accumulate during polymer vitrification. While internal stress is intrinsic to polymers that can form solids, we demonstrate that it can dramatically affect the mechanochemistry of spyropyran probes and alter their intramolecular isomerization barriers by up to 70 kJꞏmol-1. This new behavior of spiropyrans enables their application for analysis of internal stresses and their mechanochemical characterization on the molecular level. Spectroscopy and imaging based on spiropyran mechanochemistry showed high topological sensitivity and allowed to discern different levels of internal stress in various locations along the polymer chain. The nature of the developed technique allows for wide field imaging of stress heterogeneities in polymer samples of irregular shapes and dimensions, making it feasible to directly observe molecular level manifestations of mechanical stresses that accompany the formation of a vast number of solid polymer.", "pub_time": ""}
{"sha256": "a0f61ec5d018f1d54a5038b5678a97f07c40badfd61f12284a9e9c4349f0d3f7", "doi": "", "title": "Mechanistic Evidence for a Radical-Radical Recombination Pathway of Flavin-based Photocatalytic Tyrosine Labeling", "author": "Taylor O. Hope, Tamara Reyes-Robles, Keun Ah Ryu, Nicole Removski, Jacinthe Maisonneuve, Rob C. Oslund, Olugbeminiyi O. Fadeyi, Mathieu Frenette", "keyword": "Photocatalysis, proximity labeling, phenol-coupling, riboflavin tetraacetate, photoredox catalysis, radical recombination", "abstract": "We recently introduced flavin-based photocatalysts such as riboflavin tetraacetate (RFT) as a robust platform for light mediated protein labeling via phenoxyl radical-mediated tyrosine-biotin phenol coupling on live cells. To gain insight into this cou pling reaction, we conducted detailed mechanistic analysis for RFT-photomediated activation of phenols for tyrosine labeling. Con trary to previously proposed mechanisms, we find that the initial covalent binding step between the tag and tyrosine is not radical addition, but rather radical-radical recombination. Radical addition to a phenol, while often proposed in the literature, is prohibitively unfavorable according to DFT calculations. Radical-radical recombination, followed by rearomatization, is the preferred pathway for the phenol-phenol coupling presented herein, but may also explain the mechanism of other tyrosine-tagging approaches described in the literature. Competitive kinetics experiments show that phenoxyl radicals are generated by the reaction of phenols with several reactive intermediates in the proposed mechanism: primarily with the riboflavin-photocatalyst excited state or singlet oxygen, but also possibly with the semi-reduced photocatalyst or hydroperoxyl radicals produced at key steps in the mechanism.", "pub_time": ""}
{"sha256": "a125b099e6e6b038c0e89ab95d74ab1119f0d7c7d3bd186179bf8455224d2040", "doi": "", "title": "Chemical Synthesis of Glycopeptides containing L-Arabinosylated Hydroxyproline and Sulfated Tyrosine", "author": "Jasper W. van de Sande, Bauke Albada", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35c9e7e19b0507e4447c79cfdeeb9d78995076d85c76eb7453d5ce33ef5cacdc", "doi": "", "title": "Ester Transfer Reaction of Aromatic Esters with Haloarenes and Arenols by a Nickel Catalyst", "author": "Ryota Isshiki, Naomi Inayama, Kei Muto, Junichiro Yamaguchi", "keyword": "", "abstract": "A catalytic ester transfer reaction of aromatic es ters with aryl halides/arenols was developed. The present re action can transfer an ester functional group from certain aro matic esters to haloarenes. This ester transfer reaction involves two oxidative additions— one from the C–C bond of the ar omatic ester and one from the C–halogen bond of haloarenes— onto a nickel catalyst. The utilization of a Ni/dcypt catalyst capable of cleaving both chemical bonds was a key for the reaction progress. Furthermore, naphthol based aryl electrophiles were also applicable to the catalytic system via C–O bond activation. ", "pub_time": ""}
{"sha256": "d69cffc100916f9c4c2a7a7ac8e6919efe6b3e3c1b45fe38ca167dbf0643df36", "doi": "10.13023/jah.0301.05", "title": "Cancer Curriculum for Appalachian Kentucky Middle and High Schools", "author": "Lauren Hudson, Katherine Sharp, Chris Prichard, Melinda Ickes, Sahar Alameh, Nathan L. Vanderford", "keyword": "Appalachia, cancer, school curriculum, middle school, high school, students, teachers", "abstract": "Background: Appalachian Kentucky faces the highest cancer incidence and mortality rates in the country due to poor health behaviors and lifestyle choices. These poor health behaviors are facilitated by a lack of cancer education. Youth represent a vulnerable population that could be greatly impacted by increased cancer education. Teachers have the power to facilitate this learning. Purpose: This study examined the need for cancer education curriculum in Appalachian Kentucky middle and high schools from the perspective of educators. Methods: An online survey was conducted with science and health teachers (n=21) in Appalachian Kentucky, consisting of questions that investigated existing cancer education efforts, relevance of cancer education, and feasibility of such curriculum being delivered in the classroom. Content analysis was used to analyze teacher comments. A 3-part cancer education curriculum was developed that is culturally relevant and aligned with science and health education standards. Results: All participating teachers agree that cancer education is important to students’ lives. Teachers also agree that there is an inconsistent amount of cancer education within schools, and qualitative content analysis revealed that cancer education likely fits best in certain course subjects. Cancer education could feasibly be integrated into science and health classrooms, although the perception of needing to teach to the academic standards and having limited time to teach additional lessons outside of the standards are significant barriers. To combat this, a cancer curriculum that aligns with state and national science and health education standards was developed. Implications: Cancer education curriculum could play an important role in improving the cancer outlook in Appalachian Kentucky. Teachers have expressed a desire for increased cancer education in the classroom. By disseminating and implementing cancer curriculum in schools in the region and revising the curriculum -based on teacher and student feedback to better fit their needs, it has the potential to increase cancer literacy and improve related health behaviors and outcomes. ", "pub_time": "2021"}
{"sha256": "d6a2f87953e8cd8f358ee4185c45b7796719db517c6125664ade779b164bfc3f", "doi": "10.1016/j.obpill.2023.100082", "title": "The complexity of obesity-related health problems after bariatric surgery: The patient perspective", "author": "G. Konings, M. Drukker, R. Severeijns, R. Ponds", "keyword": "Long-term results Bariatric surgery Health problems Patient perspective ", "abstract": "Background: Bariatric surgery aims to improve quality of life by means of weight loss. Obesity-related physical and psychological health problems should improve, but long-term data are scarce. Objectives: To evaluate preoperative physical and mental health problems perceived by the patient and the as sociation with weight loss and quality of life, 5 years after bariatric surgery. Methods: 101 persons (response rate 67%) who had had bariatric surgery an average of 4.6 years before this study completed a written survey on obesity-related physical and psychological health problems and three psycho logical questionnaires collecting information on eating behavior and quality of life. Over half of the participants (55%) had had a laparoscopic adjustable gastric banding. Results: Preoperatively reported health problems improved but were not necessarily associated with weight loss. Minimal improvement in tiredness, shame and weight instability were associated with significantly less weight loss. Preoperative type 2 diabetes mellitus (T2D) improved but participants had significantly less weight loss and more dissatisfaction regarding the bariatric trajectory than participants without T2D. Eating concerns, emotional eating and external eating improved but not restrained eating. Compared to the Dutch population reference, most quality of life scores of the participants were lower. Conclusion: In this analysis, participants did report satisfaction although from a patients’ perspective, improve ments of weight and health did not necessarily lead to satisfaction regarding the bariatric trajectory. Participants with postoperative reported fatigue and shame as well as participants with preoperative T2D showed significant less weight loss. More long-term research is necessary to close the current knowledge gap. ", "pub_time": "2023"}
{"sha256": "d6a87c901377ed8275ec839922d1546106eaa7785182b83ca4dedb51f4f00c11", "doi": "10.1074/jbc.RA118.003348", "title": "From micelles to bicelles: Effect of the membrane on particulate methane monooxygenase activity", "author": "Soo Y. Ro, Matthew O. Ross, Yue Wen Deng, Sharon Batelu, Thomas J. Lawton, Joseph D. Hurley, Timothy L. Stemmler, Brian M. Hoffman, X Amy C. Rosenzweig", "keyword": "", "abstract": "Particulate methane monooxygenase (pMMO) is a copper-dependent integral membrane metalloenzyme that converts methane to methanol in methanotrophic bacteria. Studies of isolated pMMO have been hindered by loss of enzymatic activity upon its removal from the native membrane. To characterize pMMO in a membrane-like environment, we reconstituted pMMOs from Methylococcus (Mcc.) capsulatus (Bath) and Methylomicrobium (Mm.) alcaliphilum 20Z into bicelles. Reconstitution into bicelles recovers methane oxidation activity lost upon detergent solubilization and purification without substantial alterations to copper content or copper electronic structure, as observed by electron paramagnetic resonance (EPR) spectroscopy. These findings suggest that loss of pMMO activity upon isolation is due to removal from the membranes rather than caused by loss of the catalytic copper ions. A 2.7 Å resolution crystal structure of pMMO from Mm. alcaliphilum 20Z reveals a mononuclear copper center in the PmoB subunit and indicates that the transmembrane PmoC subunit may be conformationally flexible. Finally, results from extended X-ray absorption fine structure (EXAFS) analysis of pMMO from Mm. alcaliphilum 20Z were consistent with the observed monocopper center in the PmoB subunit. These results underscore the importance of studying membrane proteins in a membrane-like environment and provide valuable insight into pMMO function.", "pub_time": "2018"}
{"sha256": "d6a8c7a57cfb0ed79f1d2f2414f606f1b4eb037b1ba2d815f33a9eac0988f922", "doi": "10.1093/humrep/deq183", "title": "Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation", "author": "Rod T. Mitchell, Philippa T.K. Saunders, Andrew J. Childs, Claire Cassidy-Kojima, Richard A. Anderson, W. Hamish B.Wallace, Chris J.H. Kelnar, Richard M. Sharpe", "keyword": "fetal testis, disorders of sexual differentiation, testicular dysgenesis syndrome, xenografts, fetal germ cell differentiation", "abstract": " background: Abnormal fetal testis development can result in disorders of sex development (DSDs) and predispose to later testicular dysgenesis syndrome (TDS) disorders such as testicular germ cell tumours. Studies of human fetal testis development are hampered by the lack of appropriate model, and intervention systems. We hypothesized that human fetal testis xenografts can recapitulate normal development. methods: Humanfetal testes (at 9 weeks, n ¼ 4 and 14–18 weeks gestation, n ¼ 6) were xenografted into male nude mice for 6 weeks, with or without hCG treatment of the host, and evaluated for normal cellular development and function using immunohistochemistry, triple immunofluorescence and testosterone assay. The differentiation and proliferation status of germ cells within xenografts was quantified and compared with age-matched controls. results: Xenografts showed .75% survival with normal morphology. In the first-trimester xenografts seminiferous cord formation was initiated and in first- and second-trimester grafts normal functional development of Sertoli, Leydig and peritubular myoid cells was demon strated using cell-specific protein markers. Grafts produced testosterone when hosts were treated with hCG (P ¼ 0.004 versus control). Proliferation of germ cells and differentiation from gonocytes (OCT4+) into pre-spermatogonia (VASA+) occurred in grafts and quantification showed this progressed comparably with age-matched ungrafted controls. conclusions: Human fetal testis tissue xenografts demonstrate normal structure, function and development after xenografting, including normal germ cell differentiation. This provides an in vivo system to study normal human fetal testis development and its susceptibility to disruption by exogenous factors (e.g. environmental chemicals). This should provide mechanistic insight into the fetal origins of DSDs and TDS disorders", "pub_time": "2010"}
{"sha256": "35a6a903d126687537d61594137cbe19f53893b7424edfd18e9b56c5365442b4", "doi": "10.1186/1748-5908-2-26", "title": "Applying psychological theories to evidence-based clinical practice: Identifying factors predictive of managing upper respiratory tract infections without antibiotics", "author": "Martin P Eccles, Jeremy M Grimshaw, Marie Johnston, Nick Steen, Nigel B Pitts, Ruth Thomas, Elizabeth Glidewell, Graeme Maclennan, Debbie Bonetti, Anne Walker", "keyword": "", "abstract": " Background: Psychological models can be used to understand and predict behaviour in a wide range of settings. However, they have not been consistently applied to health professional behaviours, and the contribution of differing theories is not clear. The aim of this study was to explore the usefulness of a range of psychological theories to predict health professional behaviour relating to management of upper respiratory tract infections (URTIs) without antibiotics. Methods: Psychological measures were collected by postal questionnaire survey from a random sample of general practitioners (GPs) in Scotland. The outcome measures were clinical behaviour (using antibiotic prescription rates as a proxy indicator), behavioural simulation (scenario-based decisions to managing URTI with or without antibiotics) and behavioural intention (general intention to managing URTI without antibiotics). Explanatory variables were the constructs within the following theories: Theory of Planned Behaviour (TPB), Social Cognitive Theory (SCT), Common Sense Self-Regulation Model (CS-SRM), Operant Learning Theory (OLT), Implementation Intention (II), Stage Model (SM), and knowledge (a non-theoretical construct). For each outcome measure, multiple regression analysis was used to examine the predictive value of each theoretical model individually. Following this 'theory level' analysis, a 'cross theory' analysis was conducted to investigate the combined predictive value of all significant individual constructs across theories. Results: All theories were tested, but only significant results are presented. When predicting behaviour, at the theory level, OLT explained 6% of the variance and, in a cross theory analysis, OLT 'evidence of habitual behaviour' also explained 6%. When predicting behavioural simulation, at the theory level, the proportion of variance explained was: TPB, 31%; SCT, 26%; II, 6%; OLT 24%. GPs who reported having already decided to change their management to try to avoid the use of antibiotics made significantly fewer scenario-based decisions to prescribe. In the cross theory analysis, perceived behavioural control (TPB), evidence of habitual behaviour (OLT), CS-SRM cause (chance/bad luck), and intention entered the equation, together explaining 36% of the variance. When predicting intention, at the theory level, the proportion of variance explained was: TPB, 30%; SCT, 29%; CS-SRM 27%; OLT, 43%. GPs who reported that they had already decided to change their management to try to avoid the use of antibiotics had a significantly higher intention to manage URTIs without prescribing antibiotics. In the cross theory analysis, OLT evidence of habitual behaviour, TPB attitudes, risk perception, CS-SRM control by doctor, TPB perceived behavioural control and CS-SRM control by treatment entered the equation, together explaining 49% of the variance in intention. Conclusion: The study provides evidence that psychological models can be useful in understanding and predicting clinical behaviour. Taking a theory-based approach enables the creation of a replicable methodology for identifying factors that predict clinical behaviour. However, a number of conceptual and methodological challenges remain", "pub_time": "2007"}
{"sha256": "35b4231be31c34e5b6043868340cc828ee6d6a822714d8e6edeba6d161f5f491", "doi": "10.21315/mjms2022.29.1.10", "title": "Association between Dietary Diversity and Weight Status of Aboriginal Primary School Children in Negeri Sembilan, Malaysia", "author": "Divanirsh Devindran, Vaidehi Ulaganathan, Zhe Yee Oeh, Lih Xuan Tan, Silambarasi Kuralneethi, Zen Yang Eddie Eng, Lih Shiow Lim, Wei Ni Grace Chieng, Jia Ling Tay, Sook Yee Lim", "keyword": "aborigine children, food groups, diet diversity status, weight status", "abstract": " Background: The purpose of this study is to determine the association between dietary diversity and weight status of aboriginal primary school children. Methods: Dietary diversity measures food intake diversity in food groups, whereas weight status indicates nutritional status. Dietary serving score (DSS) method was used to determine dietary diversity status, while weight status was assessed using BMI-for-Age (BAZ). Results: Results reported that 51.9% and 54.2% were male and 10 years old-12 years old children, respectively. A total of 36.4% of children consumed cereal/grains diversely while fruits were not diversely consumed by 96.4% of them. Approximately 60.8% of children were reported to have normal weight status, which was followed by overweight (17.7%), obese (16.7%) and thinness to severe-thinness (4.8%). There was an association between DSS of fruits, meat/fish/ eggs, legumes/lentils and milk/dairy products with age group, vegetables DSS with gender and BAZ with parental employment status (P < 0.05). The association between DSS of all food groups and total with BAZ were reported to be insignificant, indicating no association between both variables (0.00 < r < 0.30; P > 0.05). Conclusion: Children from this study were shown to practice a monotonous diet, although the majority of them were within normal weight status.", "pub_time": "2022"}
{"sha256": "000ef75425d33b3bc398e2daff9fd5cfd16fd9aac7de90a7cd5f88842db86aa8", "doi": "10.1007/s00406-020-01164-5", "title": "Combined antisaccade task and transcranial direct current stimulation to increase response inhibition in binge eating disorder", "author": "Sebastian M. Max, \nChristian Plewnia, \nStephan Zipfel, \nKatrin E. Giel, Kathrin Schag ", "keyword": "Antisaccade, Binge eating disorder, Cognitive control, Impulsivity, Response inhibition, Transcranial direct current stimulation", "abstract": "Binge eating disorder (BED) is associated with deficient response inhibition. Malfunctioning response inhibition is linked to hypoactivation of the dorsolateral prefrontal cortex (dlPFC), where excitability could be increased by anodal transcranial direct current stimulation (tDCS). Response inhibition can be assessed using an antisaccade task which requires supressing a dominant response (i.e. saccade) towards a newly appearing picture in the visual field. We performed a double-blind, randomised, placebo-controlled proof-of-concept-study in which we combined a food-modified antisaccade task with tDCS in people with BED. We expected task learning and modulatory tDCS effects. Sixteen people were allocated to a 1 mA condition, 15 people to a 2 mA condition. Each participant underwent the food-modified antisaccade task at three measurement points: baseline without stimulation, anodal verum and sham stimulation at the right dlPFC in a crossover design. The error rate and the latencies of correct antisaccades decreased over time. No tDCS effect on the error rate could be observed. Compared to sham stimulation, 2 mA tDCS decreased the latencies of correct antisaccades, whereas 1 mA tDCS increased it. Self-reported binge eating episodes were reduced in the 2 mA condition, while there was no change in the 1 mA condition. Participants demonstrated increased response inhibition capacities by a task learning effect concerning the error rate and latencies of correct antisaccades over time as well as a nonlinear tDCS effect represented by ameliorated latencies in the 2 mA and impaired latencies in the 1 mA condition. The reduction of binge eating episodes might indicate a transfer effect to everyday life. Given that the reduction in binge eating was observed before tDCS administration, this effect could not be the result of neuromodulation. Randomized clinical trials are needed to fully understand this reduction, and to explore the efficacy of a combined antisaccade and tDCS training for BED.", "pub_time": "2020"}
{"sha256": "0012e431b8f04d8090211ca09c3e7cfc415930a1bab0837e31b0b384b8d073db", "doi": "10.1007/s40619-023-01248-z", "title": "Denosumab dopo teriparatide in donne premenopausali con osteoporosi idiopatica", "author": "Salvatore Minisola", "keyword": "", "abstract": "", "pub_time": "2023"}
{"sha256": "0014516be0d1ad20694176ce4c04fab477fc7e5e614759b6df1d3a260e360e29", "doi": "10.1007/s11295-020-01459-7", "title": "Correction to: Chloroplast genome sequences of Carya illinoinensis from two distinct geographic populations", "author": "Xinwang Wang, Hormat Shadgou Rhein, Jerry Jenkins, Jeremy Schmutz, Jane Grimwood, L. J. Grauke, Jennifer J. Randall", "keyword": "", "abstract": "", "pub_time": "2020"}
{"sha256": "0014f08104a0351063ca114668fae15481ff3cafcf833c41d966a234af4f924d", "doi": "10.1186/1754-1611-8-19", "title": "“NiCo Buster”: engineering E. coli for fast and efficient capture of cobalt and nickel", "author": "Alexandre Duprey, Viviane Chansavang, Franck Frémion, Clémence Gonthier, Yoann Louis, Philippe Lejeune, Fanny Springer, Valérie Desjardin, Agnès Rodrigue, Corinne Dorel", "keyword": "Bioremediation, Cobalt, Nickel, Biofilm, Biofilter, NiCoT, Synthetic biology", "abstract": " Background: Metal contamination is widespread and results from natural geogenic and constantly increasing anthropogenic sources (mainly mining and extraction activities, electroplating, battery and steel manufacturing or metal finishing). Consequently, there is a growing need for methods to detoxify polluted ecosystems. Industrial wastewater, surface water and ground water need to be decontaminated to alleviate the contamination of soils and sediments and, ultimately, the human food chain. In nuclear power plants, radioactive metals are produced; these metals need to be removed from effluents before they are released into the environment, not only for pollution prevention but also for waste minimization. Many physicochemical methods have been developed for metal removal from aqueous solutions, including chemical coagulation, adsorption, extraction, ion exchange and membrane separation; however, these methods are generally not metal selective. Bacteria, because they contain metal transporters, provide a potentially competitive alternative to the current use of expensive and high-volume ion-exchange resins. Results: The feasibility of using bacterial biofilters as efficient tools for nickel and cobalt ions specific remediation was investigated. Among the factors susceptible to genetic modification in Escherichia coli, specific efflux and sequestration systems were engineered to improve its metal sequestration abilities. Genomic suppression of the RcnA nickel (Ni) and cobalt (Co) efflux system was combined with the plasmid-controlled expression of a genetically improved version of a specific metallic transporter, NiCoT, which originates from Novosphingobium aromaticivorans. The resulting strain exhibited enhanced nickel (II) and cobalt (II) uptake, with a maximum metal ion accumulation of 6 mg/g bacterial dry weight during 10 min of treatment. A synthetic adherence operon was successfully introduced into the plasmid carrying the improved NiCoT transporter, conferring the ability to form thick biofilm structures, especially when exposed to nickel and cobalt metallic compounds. Conclusions: This study demonstrates the efficient use of genetic engineering to increase metal sequestration and biofilm formation by E. coli. This method allows Co and Ni contaminants to be sequestered while spatially confining the bacteria to an abiotic support. Biofiltration of nickel (II) and cobalt (II) by immobilized cells is therefore a promising option for treating these contaminants at an industrial scale. Keywords: Bioremediation, Cobalt, Nickel, Biofilm, Biofilter, NiCoT, Synthetic biolog", "pub_time": "2014"}
{"sha256": "d67641a2f3a353d81db83dd764c3bb7b39f577c17382be9e93e316c9fb46ecd7", "doi": "10.1007/s11469-020-00355-4", "title": "Malay Version of the Fear of COVID-19 Scale: Validity and Reliability", "author": " Nicholas Tze Ping Pang1 &Assis Kamu1 &Nurfarah Lydia Binti Hambali1 & Ho Chong Mun1 &Mohd Amiruddin Kassim1 & Noor Hassline Mohamed1 & Friska Ayu2 & Syed Sharizman Syed Abdul Rahim1 & Azizan Omar1 & Mohammad Saffree Jeffree1", "keyword": "COVID-19, Coronavirus. COVID-19 fear, FCV-19S Malay, Fear of COVID-19 scale, Malaysia", "abstract": " The newly developed Persian Fear of COVID-19 Scale (FCV-19S) is a seven-item uni-dimensional scale that assesses the severityof fearofCOVID-19.Atranslation and validation of the FCV-19S in the Malay language was expedited due to the severe psychological sequelae of COVID-19 in Malaysia. Formal WHO forward and backward translation sequences were employed in translating the English version into Malay. Malaysian university participants were recruited via conve nience sampling online using snowball methods. The reliability and validity prop erties of the Malay FCV-19S were rigorously psychometrically evaluated (utilising both confirmatory factor analysis and Rasch analysis) in relation to socio demographic variables and response to the depression, anxiety and stress subscales of the Malay validation of the DASS-21. The sample comprised 228 Malaysian participants. The Cronbach α value for the Malay FCV-19S was 0.893 indicating very good internal reliability. The results of the confirmatory factor analysis showed that the uni-dimensional factor structure of the FCV19S fitted well with the data. The FCV-19S-M was significantly correlated with anxiety (r=0.481, p <0.001) and stress (r=0.389, p<0.001) subscales of DASS-21. The FCV-19S M’s properties tested using Rasch analysis were also satisfactory. Hence, the Malay FCV-19S is valid and reliable, with robust psychometric properties from classical and modern psychometric methods. It therefore is a highly crucial and timely addition to the psychological toolkit both in operational and research settings in identifying, managing and responding to the psychological distress engendered by COVID-19", "pub_time": "2020"}
{"sha256": "6b348f901371fc9a4f991e2b33f62a5ce9176460fb9c442886aeed5364b1d034", "doi": "10.1186/s10086-021-01996-2", "title": "Comparison of durability of treated wood using stake tests and survival analysis", "author": "Ikuo Momohara, Haruko Sakai, Yuji Kubo", "keyword": "Stake test, Field test, Survival analysis, Wood preservative", "abstract": "The stake test is widely used to evaluate the efficacy of wood preservatives. This test monitors the deterioration level observed in treated stakes partially inserted into the ground. The results are conventionally expressed as the relation ship between deterioration levels and exposure periods. The preservative efficacy is compared among the stake groups treated with different retention levels based on the test results; however, there is no scientific basis for the comparison. We applied survival analysis to the conventional stake test to include a scientific basis to the test. Stakes impregnated with different types and retention levels of preservatives were subjected to deterioration at two test sites for approximately 30 years. The deterioration levels were monitored according to the conventional procedure and survival analysis was applied to the monitored data. Kaplan–Meier plots of the survival probabilities against the exposure periods indicated that there is a significant difference between the durability of the stakes treated with alkylammonium chloride (AAC-1) at K2 and K3 retention levels, whereas no significant difference was observed between those at K3 and K4 retention levels. Contrastingly, emulsified copper naphthenate (NCU-E) was found to be a reliable preservative, and the stakes impregnated with NCU-E showed a significant increase in durability in accord ance with preservative retention. Alkaline copper quaternary (ACQ-1) also appeared to be a reliable preservative; how ever, the increase in stake durability after ACQ-1 treatment differed between the test sites. These results were verified using the modified Gehan–Breslow–Wilcoxon test with Holm’s p adjusting method", "pub_time": "2021"}
{"sha256": "a12ceaab3c2d8bfc8d70d4dd6c126908769405c0fa3606edccdffa038402eef4", "doi": "10.1016/j.physletb.2020.135296", "title": "Improved upper limits on baryon-number violating dinucleon decays to dileptons", "author": "Sudhakantha Girmohanta, Robert Shrock", "keyword": "", "abstract": "We consider effects of n - n̄ oscillations and resultant matter instability due to dinucleon decays. We point out that existing upper bounds on the rates for the dinucleon decays nn → 2π⁰, nn → π⁺ π⁻, and np → π⁺ π⁰ imply upper bounds on the rates for dinucleon decays to dileptons nn → e⁺ e⁻, nn → μ⁺ μ⁻, nn → νℓ ν̄ℓ, and np → ℓ⁺ νℓ, where ℓ = e, μ, τ. We present estimates for these upper bounds. Our bounds are substantially stronger than corresponding limits from direct searches.", "pub_time": "2020"}
{"sha256": "35d3680f428f14c430485e6c7e38d3245abf07ae842c0303b506fb95b4081043", "doi": "10.1103/PhysRevD.101.126004", "title": "Boundary entropy under ambient RG flow in the AdS/BCFT model", "author": "Yoshiki Sato", "keyword": "", "abstract": " We discuss the change of the boundary entropy under an ambient renormalization group flow. We use conformal perturbation theory to calculate the change of the boundary entropy for d-dimensional BCFTs between two nearby fixed points. We also use the AdSdþ1=BCFTd model to calculate the boundary entropy. We show that the boundary entropy can increase under the ambient renormalization group flow both in conformal perturbation theory and the AdSdþ1=BCFTd model. In a special case, the change of the boundary entropy in the AdSdþ1=BCFTd model reduces to that of the conformal perturbation theory", "pub_time": "2020"}
{"sha256": "a0fe9a528d9605f48440bb2ca9835ce0f7b61e0febd1ac0a2f40652d60dbba58", "doi": "10.1103/PhysRevD.102.084003", "title": "Stable circular orbits in higher-dimensional multi–black-hole spacetimes", "author": "Takahisa Igata, Shinya Tomizawa", "keyword": "", "abstract": "We consider the dynamics of particles, particularly focusing on circular orbits in the higher-dimensional Majumdar-Papapetrou (MP) spacetimes with two equal mass black holes. It is widely known that in the 5D Schwarzschild-Tangherlini and Myers-Perry backgrounds, there are no stable circular orbits. In contrast, we show that in the 5D MP background, stable circular orbits can always exist when the separation of two black holes is large enough. More precisely, for a large separation, stable circular orbits exist from the vicinity of horizons to infinity; for a medium one, they appear only in a certain finite region bounded by the innermost stable circular orbit and the outermost stable circular orbit outside the horizons; for a small one, they do not appear at all. Moreover, we show that in MP spacetimes in more than 5D, they do not exist for any separations.", "pub_time": "2020"}
{"sha256": "35d6301173d2a928fc6ba07226d5c639c46f315ada5a7d33d2dc9c9b57e60980", "doi": "10.1016/j.physletb.2024.138644", "title": "Transverse momentum weighted Sivers asymmetries in SIDIS and Drell-Yan processes at COMPASS", "author": "Shi-Chen Xue a,b, Shuailiang Yang a, Xiaoyu Wang a, ,∗, De-Min Li a, Zhun Lu", "keyword": "", "abstract": " We investigate the transverse momentum weighted Sivers asymmetries in the processes with transversely polarized proton target, including the 𝑃ℎ𝑇 𝑧𝑀𝑝 sin(𝜙ℎ − 𝜙𝑆) weighted asymmetry in charged hadron production in semi-inclusive deeply inelastic scattering (SIDIS) and the 𝑞𝑇 𝑀𝑝 sin(𝜙𝑆) weighted asymmetry in 𝜋−𝑝 Drell Yan process. These asymmetries can be expressed as the product of the transverse-moments of the transverse momentum dependent (TMD) parton distribution functions (PDFs) and fragmentation functions (FFs). Using the parametrization for the Sivers function of the proton, the unpolarized PDFs of proton and pion, and the unpolarized FF of charged hadron, we present the numerical calculation for weighted Sivers asymmetries in SIDIS and Drell-Yan processes at the kinematics of COMPASS. We find that our prediction for the SIDIS process is in agreement with the recent COMPASS measurement. Recent new high-statistics data of Sivers asymmetry measured in SIDIS process and Drell-Yan process from COMPASS favored the sign change of Sivers function. High-precision experimental data of weighted asymmetries are still needed to test the sign change property o", "pub_time": "2024"}
{"sha256": "d8c8382c8847fdcdf4043acfd03c1b5125f159405b772d99960cc9129d8b531c", "doi": "10.1071/HC22005", "title": "Australian general practitioners’ perceptions of the barriers and opportunities for community-based care of patients with viral hepatitis: a mixed methods study", "author": "Belaynew Taye, Patricia Valery, Burglind Liddle, Aidan Woodward, Shaouli Shahid, Rebecca Farley, Donata Sackey, Paul Clark", "keyword": " access to healthcare, culturally and linguistically diverse populations, engagement of primary care, general practitioners, mixed methods, models of care, primary health care, shared model of care, viral hepatitis.", "abstract": "Introduction. Engagement of general practitioners (GPs) is essential to improving rates of diagnosis and treatment of viral hepatitis, as traditional tertiary hospital-based models of care often face challenges. Aim. We investigated Australian general practitioners’ perceptions of a community-based model of care for patients with viral hepatitis. Methods. We conducted a mixed methods study using survey questionnaires (23 GPs) and an open-ended interview guide (10 GPs) at primary care clinics in Brisbane, Queensland, Australia. Quantitative data were analysed using descriptive statistics in Stata 15.1 and qualitative data were analysed using thematic analysis following an inductive approach. Results. Patient loss to follow up and high cost of diagnostic tests were identified as the biggest challenges to providing care for patients with viral hepatitis. Most GPs interviewed believe a more community-based model of care with support to GPs may improve uptake of care and increase both GP and patient engagement. General practitioners felt a community-based model of care could also improve viral hepatitis testing and follow-up rates. Discussion. For Australian GPs, improving patient retention and diagnostics access were key pressure points in the viral hepatitis care pathway. A broader and more profound capacity-building allows community-based viral hepatitis care to be sustainable. ", "pub_time": "2022"}
{"sha256": "6dc6c1756c6080a6ddc99fa1fc258baa32a47a7c649434b953cab67928a72d2e", "doi": "10.1071/MA22007", "title": "‘The awesome power of yeast’", "author": "Ian MacreadieA, Sudip Dhakal", "keyword": "ageing research, cancer research, drug discovery, gene engineering, mitochondrial function, Nobel prizes, teaching, yeast-derived vaccines", "abstract": "Yeast is one of the most useful microorganisms in society. Aside from the well known traditional uses in beer, wine and bread making, yeast is currently providing new opportunities for our society. This article examines some of those new opportunities which include using yeast as a model organism, yeast as a cell factory for valuable proteins, including vaccines and new therapeutics, and yeast as a very convenient tool for teaching. ", "pub_time": "2022"}
{"sha256": "d94c8cc4ab107c9f54b7a1e7787df215a1440b349da03c14f0c8ddec258acca4", "doi": "10.1071/RD21161", "title": "Changes in mononuclear immune cells during bovine pregnancy", "author": "Heloisa M. Rutigliano, Kelsy A. Leppo, Kira P. Morgado", "keyword": " bovine gestation, diestrous, endometrium, gene expression, immune cell, leukocyte, lymphocyte, maternal–fetal interface, placenta, regulatory T cell.", "abstract": "This study aimed to determine the differences in gene expression between mononuclear cells derived from peripheral blood and endometrium during pregnancy in cattle and to determine the proportion of mononuclear cells in the endometrium of pregnant and diestrous cows. Endometrial tissue and peripheral blood were collected from Day 34 ± 2 pregnant cows, and mononuclear cell populations were quantified and sorted (n = 5). The relative mRNA levels of inflammatory mediators was assessed by quantitative real time polymerase chain reaction. During pregnancy, the proportion of CD8+ , CD4+,CD4+CD25− and CD4+CD25dim cells among mononuclear cells was greater in blood than endometrium, and cells positive for CD14 and CD68 expressed greater mRNA amounts of interleukin (IL) 6, CXCL8 and IL10 in endometrium compared with blood. Cells positive for γ/δ-T cell receptor expressed greater amounts of IL1A transcript in the endometrium than in blood of diestrous cows, CD4+CD25bright cells expressed more CTLA4 mRNA in the endometrium compared with blood of diestrous cows, and endometrial natural killer cells expressed greater CXCL8 mRNA compared with blood of pregnant and diestrous cows. The percentages of CD21+ , NCR1+ , CD8+ , FoxP3+ , CD3+ and CD68+ cells were greater in the endometrium of Day 35 pregnant cows compared with diestrous cows.", "pub_time": "2022"}
{"sha256": "6f538b8c48d124db6a0fc96a2c073c148368ca64c5cc7236ec9b3811902272c4", "doi": "10.1071/SH22024", "title": "Optimising the delivery of sexual health services in Australia: a qualitative study", "author": "Varsicka Kularadhan, Christopher K. Fairley, Marcus Chen, Jade Bilardi, Ria Fortune, Eric P. F. Chow, Tiffany Philips, Jason J. Ong", "keyword": "Australian sexual health services, health service delivery, HIV, priority populations, service providers, sexually transmitted infection, strategies, strategies to optimise", "abstract": "Background. With a rise in sexually transmitted infections in Australia, it is important to evaluate and optimise current sexual health services to reduce barriers to access and increase testing. We aimed to describe the range of sexual health services in Australia, focusing on strategies to improve testing among priority populations, and any future strategies participants believed would improve service delivery. Methods. We conducted 20 semi-structured interviews with key informants working in Australian sexual health services from July to December 2020, and collected data on service characteristics and strategies to improve access. We used content analysis, then coded and categorised the data into recurring themes and sub-themes. Results. We identified two major themes: ‘Expanding Traditional Service Delivery’ and ‘Thinking Outside the Box’. The first theme outlines strategies that build upon pre-existing service delivery models, such as express clinics and an increased focus on confidentiality. The second theme outlines new strategies introduced to fill gaps in service delivery, such as self-testing and outreach. Conclusions. To improve access to HIV/STI testing, there is a need for multiple access points to cater for a range of populations and their preferences. Establishing strategies to accomplish this involves utilising a combination of expanding traditional service models and implementing new approaches to service delivery.", "pub_time": "2022"}
{"sha256": "da77336fdfe6568415c4b43a284edcff8d98752918ed40be19f3a9212cf1bc38", "doi": "", "title": "Statistical modelling of tropical cyclones’ longevity after landfall in Australia ", "author": "Kamal K Saha, Saleh A Wasimi", "keyword": "", "abstract": "Most of the devastation caused by a tropical cyclone occurs on land, and there fore, its longevity after landfall is of critical importance. Published literature identifies many factors including inland environmental characteristics that influ ence this longevity as well as power dissipation rate. These have been studied in this research in the context of tropical cyclones that hit Australian coasts during the period 1984-2010. For obvious reasons, tropical cyclones which manifested recurrence or multiple landfalls have been excluded. After applying several sta tistical tools to the observed data, it has been found, from the list of variables identified in literature related to tropical cyclones, that storm intensity at land fall, translation speed, relative humidity, surface temperature, upper level diver gence, and surface roughness exhibited statistical significance. However, step wise regression retained only surface roughness and central pressure which yielded a coefficient of determination of 76 percent during calibration and 59 percent during validation with 60%/40% split in data. The influence of surface roughness is well understood, but as yet, no consistent metric for the purpose of tropical cyclones’ propagation exists, and therefore, this paper introduces a method of assigning surface roughness based on terrain characteristics.", "pub_time": "2015"}
{"sha256": "71cebfda6feb9a90381617df190539af5b149a0ddd838d8b75427ca316a5b097", "doi": "10.1071/WF20168", "title": "Bureaucratic inertia in dealing with annual forest fires in Indonesia", "author": "Eko Priyo Purnomo, Rijal Ramdan, Agustiyara , Achmad Nurmandi, Dina Wahyu Trisnawati, Aqil Teguh Fathani", "keyword": "bureaucratic inertia, collaboration, coordination, forest fire, Indonesia", "abstract": " Indonesia has sustained annual forest fires since the 1990s related to land clearing activities for agriculture. The Indonesian Government has made substantial efforts to resolve annual fires by improving intergovernmental coordination at national and local levels. Overall, 96 government agencies are liable for controlling forest fire. This study explores local to central government’s bureaucratic reluctance in addressing forest fires, focusing on Riau Province, the most forest fire-prone region in Indonesia. Data were collected from 2015 to 2019 using participatory observation, engaging in meetings of key players; in-depth interviews with key heads of relevant agencies, officials, and NGOs; and a questionnaire forSocialNetworkAnalysis.Theresultsshowthatthereareseveninfluentialinstitutionsforaddressingland andforestfires inRiau.However,thepowerofthedecision-makingprocessisconcentratedatthelevelofthePresidentand the Governor as the regional leader, which implies that large institutions involved in fire response have less power and responsibility owing in part to bureaucratic inertia as bureaucracy is overly centralised and less responsive. In the long term,devolutionofgovernmentauthorityfromthecentraltothelocallevelisrequiredtofurnishfront-lineinstitutionswith the power to deal with the fires", "pub_time": "2021"}
{"sha256": "d6b8aff0be2d4516fd43c3a13470c14d7f4b51d29ff05bfdf0fa9123a4dbc86e", "doi": "10.25338/B81S5M", "title": "Nudging consumers toward greener air travel by adding carbon to the equation in online flight search", "author": "Angela Sanguinetti, Nina Amenta", "keyword": "Carbon Emissions, Air Travel, Flight Search, Interface Design, Online Travel Booking ", "abstract": "This study explores the potential to promote lower-emissions air travel by providing consumers with information about the carbon emissions of alternative flight choices in the context of online flight search and booking. We surveyed over 450 employees of the University of California, Davis, asking them to choose among hypothetical flight options for university-related business trips. Emissions estimates for flight alternatives were prominently displayed alongside cost, layovers and airport, and the lowest-emissions flight was labeled “Greenest Flight”. We found an impressive rate of willingness to pay for lower-emissions flights: around $200/ton of CO2e saved, a magnitude higher than that seen in carbon offsets programs, and consistent with findings from a prior study with a non-university-based sample. In a second step of analysis, we estimated the carbon and cost impacts if the university were to adopt a flight-search interface that prioritizes carbon emissions information and displays alternatives from multiple regional airports in their employee travel-booking portal. We estimated potential annual savings of 79 tons of CO2e, while reducing airfare costs by $56,000, mainly due to an increased willingness of travelers to take advantage of cheaper nonstop (lower-emissions) flights from a more distant airport in the region over indirect flights from their preferred airport for medium-distance flights. Institutionalizing this strategy within organizations with large travel budgets could reduce personal and organizational carbon footprints. If implemented across major flight search engines, it could potentially reduce the demand for higher-emissions flights leading to an industry-wide impact on aviation emissions. ", "pub_time": "2021"}
{"sha256": "35a5419e4b7309d6b6b71b0f9a893dabeb56863e41d1f6cc531c38af09f54cdf", "doi": "", "title": "The Effect of Electoral Institutions on Tort Awards", "author": "Eric Helland,  Alexander Tabarrok", "keyword": "", "abstract": "Politicians are not neutral maximizers of the public good, they respond to incentives just like other individuals. We apply the same reasoning to those politicians in robes called judges. We argue that elected judges, particularly partisan elected judges, have an incentive to redistribute wealth from out-of-state defendants (non-voters) to in-state plaintiffs (voters). The partisan electoral hypothesis is tested first using data on 75,000 tort awards from across the states. We control for differences in injuries, state incomes, poverty levels, selection effects and other factors that may cause awards to differ across the states. One difference which appears difficult to control for is that each state has its own body of tort law. We take advantage of a peculiar aspect of American Federalism to make this distinction. In cases involving citizens of different states, aptly called diversity of citizenship cases, Federal judges apply state law to decide disputes. Diversity of citizenship cases allows us to test whether differences in awards are caused by differences in electoral systems or differences in state law. The evidence from the cross-state regressions and from the diversity of citizenship cases, strongly supports the partisan election hypothesis. In cases involving out-of-state defendants and in-state plaintiffs the average award (conditional on winning) is 42% higher in partisan than in non-partisan states; approximately 2/3 ds of the larger award is due to a bias against out-of-state defendants and the remainder due to generally higher awards against businesses in partisan states.", "pub_time": "2001"}
{"sha256": "0006a57c04ffd00af1fa0ef2c9de5325fe8b05f03faa3eb5ac8739a28d3b3af2", "doi": "10.5194/acp-4-215-2004", "title": "Tethered balloon measurements of biogenic volatile organic compounds at a Boreal forest site", "author": "C. Spirig, A. Guenther, J. P. Greenberg, P. Calanca, V. Tarvainen", "keyword": "", "abstract": " Measurements of biogenic volatile organic com pounds (VOCs) were performed at Hyyti¨al¨a, a Boreal for est site in Southern Finland as part of the OSOA (origin and formation of secondary organic aerosol) project in August 2001. At this site, frequent formation of new particles has been observed and the role of biogenic VOCs in this pro cess is still unclear. Tethered balloons served as platforms to collect VOC samples within the planetary boundary layer at heights up to 1.2km above ground during daytime. Mean mixed layer concentrations of total monoterpenes varied be tween 10 and 170pptv, with α-pinene, limonene and 13 carene as major compounds, isoprene was detected at levels of 2–35pptv. A mixed layer gradient technique and a budget approach are applied to derive surface fluxes representative for areas of tens to hundreds of square kilometres. Effects of spatial heterogeneity in surface emissions are examined with a footprint analysis. Depending on the source area consid ered, mean afternoon emissions of the sum of terpenes range between 180 and 300µgm−2h−1 for the period of 2–12 Au gust 2001. Surface fluxes close to Hyyti¨al¨a were higher than the regional average, and agree well with mean emissions predicted by a biogenic VOC emission model. Total rates of monoterpene oxidation were calculated with a photochemi cal model. The rates did not correlate with the occurrence of new particle formation, but the ozone pathway was of more importance on days with particle formation. Condens able vapour production from the oxidation of monoterpenes throughout the mixed layer can only account for a fraction of the increase in aerosol mass observed at the surface", "pub_time": "2004"}
{"sha256": "0017f8dfa12f73d3c67f939f180cc94cbde8e9a835949cdcd763f8be7363389c", "doi": "", "title": "Gestational Surrogacy: Participants’ Discussion and Decision Making Regarding Pregnancy Management, Including Prenatal Testing and Pregnancy Complication ", "author": "Susy Malca", "keyword": "", "abstract": "While gestational surrogacy has grown in popularity in the last decade, the surrogacy process is far from homogeneous. This lack of standardization can cause problems between surrogates and intended parents and can be troublesome for healthcare providers. The purpose of this study was to understand the current practices regarding discussion of potential pregnancy complications and prenatal testing in an attempt to determine how these decisions are made. This study also examined how comfortable surrogates felt expressing their opinions with the intended parents regarding these topics. Surveys were distributed through four surrogacy agencies and included several topics that could pose a potential conflict between the surrogates and intended parents. One hundred and eleven participants were included in this study. Decisional topics included carrier screening, fetal anomalies, and screening/testing options. The number of topics discussed by the surrogates varied, with about 1/3 of participants reporting that they discussed most or all of these topics before being matched with the intended parents. Decisions during the pregnancy were most often made by medical professionals, followed by the gestational surrogate and intended parent(s) together. Most participants felt comfortable voicing their opinions and that their opinions were vi considered throughout the surrogacy experience. These results indicate that surrogates generally feel comfortable and empowered throughout their experience. The results of this study revealed overall positive experiences for the surrogates. Having standardized guidelines may increase satisfaction with the surrogacy process and be beneficial in preventing serious conflicts between surrogates and intended parents. Given the recent increase in prenatal screening and testing options, standardized guidelines are needed to assist genetic counselors with facilitating discussions between surrogates and intended parent(s)", "pub_time": "2016"}
{"sha256": "6b4c79aee6adb6df2e71faa851009134aba4faf34331ec14be1753e751a23b61", "doi": "", "title": "Who Cares for Infants and Toddlers? A Mixed Methods Study of Child Care for Low-Income Families", "author": "Jennifer Lynn Marcella", "keyword": "", "abstract": "Despite trends indicating that low-income, Latino families underuse licensed child care (Chaudry et al., 2011; Howes et al., 2007), questions remain about why these mothers do not use infant and toddler child care programs. Therefore, this mixed methods case study of a Los Angeles community illustrates the interplay of licensed child care availability with maternal preferences regarding infant and toddler care arrangements. Community demographic data as well as availability and quality of licensed child care data provided the descriptive community context. Family survey data depicted trends in child care use of a predominantly low-income sample of 556 mothers living in the community. Lastly, semi-structured interviews were conducted with a subsample of 28 family survey mothers to shed light on mothers’ beliefs about infant and toddler child care. Taken together, these sources of data indicated that limited infant and toddler licensed care was available, and few programs served specifically low-income families. Within this ii community child care context, mothers had a limited awareness of the available licensed care. Additionally, these mothers expressed negative impressions of licensed care, which seemed warranted based on the observational data on programs serving low-income families. From this study, policymakers should strive to improve the quality of care for all infant and toddler programs while also better designing and marketing child care assistance programs to meet the needs of low-income families. Practitioners can utilize these findings by learning about the concerns of low-income mothers, addressing any shortcomings their programs face, and better communicating with new mothers to allay fears about group care. ", "pub_time": "2014"}
{"sha256": "39025c9a849702b60387c547a604b6d43659b7a67cd87eb8ae16ae51d1855ab7", "doi": "10.3174/ajnr.A7223", "title": "Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement", "author": " L. Saba, W. Brinjikji, J.D. Spence, M. Wintermark, M. Castillo, G.J. de Borst, Q. Yang, C. Yuan, A. Buckler, M. Edjlali, T. Saam, D. Saloner, B.K. Lal, D. Capodanno, J. Sun, N. Balu, R. Naylor, A.v.d. Lugt, B.A. Wasserman, Kooi, J. Wardlaw, J. Gillard, G. Lanzino, U. Hedin, D. M.E. Mikulis, A. Gupta, J.K. DeMarco, C. Hess, J.V. Goethem, T. Hatsukami, P. Rothwell, M.M. Brown and A.R. Moody", "keyword": "", "abstract": " Current guidelines for primary and secondary prevention of stroke in patients with carotid atherosclerosis are based on the quantification of the degree of stenosis and symptom status. Recent publications have demonstrated that plaque morphol ogy and composition, independent of the degree of stenosis, are important in the risk stratification of carotid atherosclerotic dis ease. This finding raises the question as to whether current guidelines are adequate or if they should be updated with new evidence, including imaging for plaque phenotyping, risk stratification, and clinical decision-making in addition to the degree of ste nosis. To further this discussion, this roadmap consensus article defines the limits of luminal imaging and highlights the current evi dence supporting the role of plaque imaging. Furthermore, we identify gaps in current knowledge and suggest steps to generate high-quality evidence, to add relevant information to guidelines currently based on the quantification of stenosis", "pub_time": "2021"}
{"sha256": "a607eb96ec8730db857de38bdaba24ff74e6715c06087917a64e51ece5e91046", "doi": "10.3174/ajnr.A6209", "title": "White Matter Abnormalities in Multiple Sclerosis Evaluated by Quantitative Synthetic MRI, Diffusion Tensor Imaging, and Neurite Orientation Dispersion and Density Imaging", "author": "A. Hagiwara, K. Kamagata, K. Shimoji, K. Yokoyama, C. Andica, M. Hori, S. Fujita, T. Maekawa, R. Irie, T. Akashi, A. Wada, M. Suzuki, O. Abe, N. Hattori, S. Aoki", "keyword": "", "abstract": " BACKGROUNDANDPURPOSE:AnumberofMR-derivedquantitativemetricshavebeensuggestedtoassess thepathophysiol ogyofMS, but thereportsaboutcombinedanalysesof thesemetricsarescarce.Our aimwas toassess thespatial distribu tionofparameters forwhitemattermyelinandaxon integrity inpatientswithrelapsing-remittingMSbymultiparametricMR imaging. MATERIALSANDMETHODS:Twenty-four patientswith relapsing-remittingMSand24age- andsex-matchedcontrolswerepro spectively scannedbyquantitativesyntheticand2-shell diffusionMR imaging. SyntheticMR imagingdatawereusedtoretrieve relaxometryparameters (R1 andR2relaxationratesandprotondensity) andmyelinvolumefraction.Diffusiontensormetrics (frac tional anisotropyandmean, axial, andradial diffusivity) andneuriteorientationanddispersion indexmetrics (intracellular volume fraction, isotropicvolume fraction, andorientationdispersion index)were retrievedfromdiffusionMR imagingdata. Thesedata wereanalyzedusingTract-BasedSpatialStatistics. RESULTS:PatientswithMSshowedsignificantlylower fractionalanisotropyandmyelinvolumefractionandhigher isotropicvolume fraction inwidespreadwhitematter areas.Areaswithdifferent isotropicvolumefractionswere includedwithinareaswith lower fractional anisotropy.Myelinvolumefractionshowednosignificantdifference insomeareaswithsignificantlydecreasedfractional anisotropy inMS, including inthegenuof thecorpuscallosumandbilateral anteriorcoronaradiata,whereasmyelinvolumefrac tionwas significantlydecreasedinsomeareaswherefractional anisotropyshowednosignificantdifference, includingthebilateral posterior limboftheinternalcapsule,externalcapsule, sagittal striatum, fornix, anduncinatefasciculus. CONCLUSIONS:Wefounddifferences inspatialdistributionofabnormality infractional anisotropy, isotropicvolumefraction, and myelinvolumefractiondistributioninMS,whichmightbeuseful forcharacterizingwhitematter inpatientswithMS.", "pub_time": "2019"}
{"sha256": "db6f896fa4a15ed550cc1c045783bbe6c05dc61cd59dd2228045d1f6f6b63de6", "doi": "10.3174/ajnr.A7464", "title": "PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice", "author": "C. Pedersen, M. Aboian, J.E. McConathy, H. Daldrup-Link, and A.M. Franceschi", "keyword": "", "abstract": "SUMMARY: Modern pediatric imaging seeks to provide not only exceptional anatomic detail but also physiologic and metabolic information of the pathology in question with as little radiation penalty as possible. Hybrid PET/MR imaging combines exquisite softtissue information obtained by MR imaging with functional information provided by PET, including metabolic markers, receptor binding, perfusion, and neurotransmitter release data. In pediatric neuro-oncology, PET/MR imaging is, in many ways, ideal for follow-up compared with PET/CT, given the superiority of MR imaging in neuroimaging compared with CT and the lower radiation dose, which is relevant in serial imaging and long-term follow-up of pediatric patients. In addition, although MR imaging is the main imaging technique for the evaluation of spinal pathology, PET/MR imaging may provide useful information in several clinical scenarios, including tumor staging and follow-up, treatment response assessment of spinal malignancies, and vertebral osteomyelitis. This review article covers neuropediatric applications of PET/MR imaging in addition to considerations regarding radiopharmaceuticals, imaging protocols, and current challenges to clinical implementation.", "pub_time": "2022"}
{"sha256": "082bd6d1842cecfeb587546dd5efad77fe51b84c0551a9995f12a88d1b122a35", "doi": "10.3174/ajnr.A7358", "title": "Deep Learning Enables 60% Accelerated Volumetric Brain MRI While Preserving Quantitative Performance: A Prospective, Multicenter, Multireader Trial", "author": "S. Bash, L. Wang, C. Airriess, G. Zaharchuk, E. Gong, A. Shankaranarayanan, L.N. Tanenbaum", "keyword": "", "abstract": "BACKGROUND AND PURPOSE: In this prospective, multicenter, multireader study, we evaluated the impact on both image quality and quantitative image-analysis consistency of 60% accelerated volumetric MR imaging sequences processed with a commercially available, vendor-agnostic, DICOM-based, deep learning tool (SubtleMR) compared with that of standard of care.\nMATERIALS AND METHODS: Forty subjects underwent brain MR imaging examinations on 6 scanners from 5 institutions. Standard of care and accelerated datasets were acquired for each subject, and the accelerated scans were enhanced with deep learning processing. Standard of care, accelerated scans, and accelerated–deep learning were subjected to NeuroQuant quantitative analysis and classified by a neuroradiologist into clinical disease categories. Concordance of standard of care and accelerated–deep learning biomarker measurements were assessed. Randomized, side-by-side, multiplanar datasets (360 series) were presented blinded to 2 neuroradiologists and rated for apparent SNR, image sharpness, artifacts, anatomic/lesion conspicuity, image contrast, and gray-white differentiation to evaluate image quality.\nRESULTS: Accelerated–deep learning was statistically superior to standard of care for perceived quality across imaging features despite a 60% sequence scan-time reduction. Both accelerated–deep learning and standard of care were superior to accelerated scans for all features. There was no difference in quantitative volumetric biomarkers or clinical classification for standard of care and accelerated–deep learning datasets.\nCONCLUSIONS: Deep learning reconstruction allows 60% sequence scan-time reduction while maintaining high volumetric quantification accuracy, consistent clinical classification, and what radiologists perceive as superior image quality compared with standard of care. This trial supports the reliability, efficiency, and utility of deep learning–based enhancement for quantitative imaging. Shorter scan times may heighten the use of volumetric quantitative MR imaging in routine clinical settings.", "pub_time": "2021"}
{"sha256": "733b0250bc54a98b94a2c2ef19d2a2bfb9394766d4dcfbd57a79972a3f6a312f", "doi": "10.3174/ajnr.A3113", "title": "Whither the Hippocampus? FDG-PET Hippocampal Hypometabolism in Alzheimer Disease Revisited", "author": "J.A. Maldjian, C.T. Whitlow", "keyword": "", "abstract": " BACKGROUNDANDPURPOSE: ThehippocampusisawidelyrecognizedareaofearlychangeinAD,yet voxelwiseanalysesofFDG-PETactivitydifferencesbetweenADandCNcontrolshaveconsistently failedto identifyhippocampal hypometabolism. Inthisarticle,weproposeahigh-dimensionalPET specificanalysisframeworktodeterminewhetherimportanthippocampalmetabolicFDG-PETactivity differencesbetweenpatientswithADandCNsubjectsareembedded intheJacobian information generatedduringspatialnormalization. MATERIALSANDMETHODS: RestingFDG-PETdatawereobtainedfrom102CNand92participantswith ADfromtheADNIdatabase.APET-study-specifictemplatewasconstructedusingsymmetricdiffeomor phicregistration.SpatiallynormalizedrawFDGmaps,Jacobiandeterminantmaps,andmodulatedmaps weregenerated for all subjects. Statistical parametricmappingand tensor-basedmorphometrywere performed,comparingpatientswithADwithCNsubjects. RESULTS:Whole-brainspatiallynormalizedrawFDGmapsdemonstratedrobusthypometabolismin cingulategyrusandbilateral parietal areas.Nohippocampal differenceswerepresent, except on ROI-basedanalyseswithahippocampalmask.Whole-brainmodulatedmapsdemonstratedrobust bilateralhippocampalhypometabolism,andsomehypometabolismintheposteriorcingulate.Tensor basedmorphometrydemonstratedrobusthippocampaldifferencesonly. CONCLUSIONS: Theseresultsdemonstratethathippocampalmetabolicdifferencesareembeddedin theJacobian informationfromthespatial normalizationprocedure.We introduceavoxelwisePET specificanalysisframeworkbasedontheuseofaPET-population-specifictemplate,high-dimensional symmetricdiffeomorphicnormalization, and theuseof Jacobian information,whichcanprovide substantiallyincreasedstatisticalpowerandanorderofmagnitudedecreaseinimagingcosts.", "pub_time": "2012"}
{"sha256": "dcb6a63364cc8af0a68cc037f6e6979a277dc36d854963d52e277c08922b52bd", "doi": "10.3174/ajnr.A2402", "title": "Magic Angle Effect: A Relevant Artifact in MR Neurography at 3T?", "author": "T. Kästel, S. Heiland, P. Bäumer, A.J. Bartsch, M. Bendszus, M. Pham", "keyword": "", "abstract": " BACKGROUNDANDPURPOSE:MRNisanemergingdiagnosticmethod for disordersof peripheral nerves.However, it isunclearwhether the influenceof theMAon intraneural T2signal issevere enoughtoprovokefalse-positivefindings. MATERIALSANDMETHODS: Twenty-fivehealthysubjectsunderwentMRNofthesciaticnerveofthe proximalthighat3T.TheT2appwascalculatedfromaDE-TSEsequence(TR 3000ms,TE1 12ms, TE2 69ms)at7anglesof thesciaticnerverelativetoB0 0°,30°,35°,40°,45°,50°,and55°. Precise angle adjustmentswereperformedwith a dedicated in-borepositioning aid. Qualitative evaluationofintraneuralT2-weightedcontrastbetweenthisgroupofhealthysubjectsand14patients withneuropathic lesionswasperformedbycomparingCNRsofaTIRMsequence(TR 5000ms, TE 76ms,TI 180ms). RESULTS: Inhealthysubjects, theprolongationofT2app from0° to55°was from74.5 13.4to 104.0 16.9ms(P .001).TheincreaseinT2apprelativetobaseline(0°)was9.6%(30°),18.4%(35°), 25%(40°),27.6%(45°),and37%(55°). IntraneuralCNRincreasedby1.98 0.69at40°and2.93 0.46at55°.Nevertheless, themeanCNRofhealthysubjectswassubstantially lower thanthat in patientsat40°(P .0001)andevenatthepositionofmaximumMA(55°:20.6 5.11versus52.6 7.12,P .0001). CONCLUSIONS: Neuropathiclesionsareclearlydistinguishablefromanartificial increaseofintraneural T2bytheMA.EvenatamaximumMA(55°),thefalse-positivedeterminationofaneuropathiclesion isunlikely", "pub_time": "2011"}
{"sha256": "08abeadc9bddd1ed1752af229387a97d2a1083e2ac41510ac04c42094f2c37c0", "doi": "10.3174/ajnr.A4336", "title": "Evolution of Flow-Diverter Endothelialization and Thrombus Organization in Giant Fusiform Aneurysms after Flow Diversion: A Histopathologic Study", "author": "I. Szikora, E. Turányi, M. Marosfoi", "keyword": "", "abstract": "BACKGROUND AND PURPOSE: Treatment of giant fusiform aneurysms with flow diverters has been associated with a relatively high rate of complications. Our goal was to study the evolution of flow-diverter endothelialization and thrombus organization at different time points after flow-diverter treatment in giant fusiform aneurysms to better understand reasons for flow-diverter thrombosis and delayed aneurysm ruptures. \nMATERIALS AND METHODS: Two giant anterior and 2 posterior circulation aneurysms, all of which had partially thrombosed before treatment, were studied. An unruptured, untreated posterior circulation aneurysm was used as a control. Each specimen was removed at 7 days or at 6, 9, or 13 months after flow-diverter treatment. The 3 patients who survived longer than 7 days were followed up by angiography and MR imaging. Formaldehyde-fixed paraffin-embedded sections were stained by using H&E, Van Gieson elastic, CD34, h-Caldesmon, and Picrosirius stains and studied by light microscopy. RESULTS: According to angiography, aneurysms were found to be obliterated partially at 6 and 9 months and completely at 13 months. MR imaging revealed that mass effect remained unchanged in each case. Sections of the flow diverter within the normal parent artery were covered by an endothelialized fibrous layer as early as 6 months, but there was no tissue coverage or endothelialization seen even at 13 months inside the aneurysm itself. Each treated aneurysm had a thin wall with complete lack of smooth muscle cells. No signs of thrombus organization were found at any of the time points studied. \nCONCLUSIONS: Endothelialization of the flow diverter in giant fusiform aneurysms may not occur and thrombus organization may not be initiated inside these aneurysms for as long as 1 year, which explains delayed flow-diverter thrombosis and the possibility of delayed ruptures.", "pub_time": "2015"}
{"sha256": "a936ec60aa6db7b1a5fdb8d74ecb16e68b14d3fa30c63abfd2a2e4635b0ed64b", "doi": "10.3174/ajnr.A5452", "title": "Hemodynamic Changes Caused by Multiple Stenting in Vertebral Artery Fusiform Aneurysms: A Patient-Specific Computational Fluid Dynamics Study", "author": "N. Lv, W. Cao, I. Larrabide, C. Karmonik, D. Zhu, J. Liu, Q. Huang, Y. Fang", "keyword": "", "abstract": " BACKGROUNDANDPURPOSE: Themultiplestentplacementtechniquehaslargelyimprovedthelong-termoutcomesofintracranial fusiformaneurysms,butthehemodynamicmechanismsremainunclear. Inthisstudy,weanalyzedthehemodynamicchangescausedby differentstent-placementstrategies inpatient-specificmodelsusingthecomputationalfluiddynamicstechnique, aimingtoprovide evidenceforclinicaldecision-making. MATERIALSANDMETHODS: Tenvertebral arteryfusiformaneurysmswereincluded, andtheirpatient-specificcomputationalfluid dynamicsmodelswerereconstructed.Afastvirtualstentplacementtechniquewasusedtosimulatesequentialmultiplestentplacements (fromasinglestenttotriplestents) inthevertebralarteryfusiformaneurysmmodels.Hemodynamicparameters, includingwallshear stress,pressure,oscillatoryshear index, relativeresidencetime,andflowpattern,werecalculatedandcomparedamonggroupswith differentnumbersofstents. RESULTS: Virtualstentsweredeployedinall10casessuccessfully,consistentwiththerealstentconfiguration.Wallshearstressdecreased progressivelyby7.2%,20.6%,and25.8%asthenumberofstentsincreased.Meanwhile,relativeresidencetimeandpressureincreasedon averageby11.3%, 15.4%, and45.0%andby15.7%,21.5%, and28.2%.Theoscillatoryshear indexshowednostablevariationtrend. Flow patternsimprovedbyweakeningtheintensityofthevorticesanddisplacingthevortexcenterfromtheaneurysmalwall. CONCLUSIONS: Stentplacementmodifieshemodynamicpatterns invertebralarteryfusiformaneurysms,whichmightfavorthrombosis formationintheaneurysmalsac.Thiseffectisamplifiedwiththenumberofstentsdeployed.However,apotentialriskofruptureorrecanaliza tionexistsandshouldbeconsideredwhenplanningtousethemultiplestentplacementtechniqueinvertebralarteryfusiformaneurysms.", "pub_time": "2018"}
{"sha256": "3c7fc1c7aff2ab29617055903195b879545a0563a48a29a5b720f3247a44cd43", "doi": "10.3174/ajnr.A2721", "title": "Intracranial Meningeal Hemangiopericytomas in Children and Adolescents: CT and MR Imaging Findings", "author": "Q. Chen, X.-Z. Chen, J.-M. Wang, S.-W. Li, T. Jiang, J.-P. Dai", "keyword": "", "abstract": " SUMMARY: Intracranialmeningeal hemangiopericytomas inchildrenandadolescentsareprone to bleedingduringsurgery.CTandMRimagingmayservearoleinpreoperativediagnosis.Thepurpose of thisreportwastodescribetheradiologicfindings in9pathologicallyprovedcasesof intracranial meningealhemangiopericytomasinchildrenandadolescents.Theaveragedurationofsymptomswas short (mean,4.0months;median,1.5months).Theintraoperativebloodlosswaslarge(mean,3561 mL;median,1000mL).Tumorswereextra-axial, irregularlymultilobular,andhypervascular.Radiolog ically, theyshowedmixedattenuationonprecontrastCTimages,heterogeneoussignal intensityon precontrastMRimaging,andmarkedandheterogeneousenhancementonpostcontrastMRimaging. Boneerosionwassometimespresent,buthyperostosiswasnotpresent.OnMRimaging,multiple signal intensityvoidsofvesselswereobservedin100%(8/8)oftumorswithAVM-likesignal intensity flowvoidsin25%(2/8)of tumors.Theseresultssuggest thatCTandMRimagingfindingsmaybe helpful forpreoperativediagnosis", "pub_time": "2012"}
{"sha256": "a31394474d19c7194249b5e4a22297eaf46b337f0528191747e017a2e44f3d9c", "doi": "10.3174/ajnr.A5564", "title": "Relationship between Ischemic Injury and Patient Outcomes after Surgical or Endovascular Treatment of Ruptured Anterior Communicating Artery Aneurysms", "author": "S. Mugikura, S. Takahashi, K. Takase", "keyword": "", "abstract": "", "pub_time": "2018"}
{"sha256": "3a6a4028a7c162cf7bc246a0899cced0f855e3a0d0ad9284d4bed96a5a9007e0", "doi": "10.3174/ajnr.A6582", "title": "Tandem Carotid Lesions in Acute Ischemic Stroke: Mechanisms, Therapeutic Challenges, and Future Directions", "author": "A.Y. Poppe, G. Jacquin, D. Roy, C. Stapf, L. Derex", "keyword": "", "abstract": " SUMMARY: Approximately 15% of patients undergoing endovascular thrombectomy for anterior circulation acute ischemic stroke have a tandem lesion, defined as a severe stenosis or occlusion of the cervical internal carotid artery ipsilateral to its intracranial occlusion. Patients with tandem lesions have worse outcomes than patients with isolated intracranial occlusions, but the optimal management of their carotid lesions during endovascular thrombectomy remains controversial. The main options commonly used in current practice include acute stent placement in the carotid lesion versus thrombectomy alone without definitive revasculariza tion of the carotid artery. While treatment decisions for these patients are often complex and strategies vary according to clinical, anatomic, and technical considerations, only results from randomized trials comparing these approaches are likely to strengthen current recommendations and optimize patient care", "pub_time": "2020"}
{"sha256": "a12062e84024465d2e3d82b8c2f651f85da4b88910bf48f3bab743bcbe5c8887", "doi": "", "title": "对《招标投标法》的误解和滥用是落实供应链战略的障碍", "author": "陈川生", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "6b7970b27493a9428acac88cc40fd51239fc449cd6945d119da9d081ffdb35f2", "doi": "10.3760/cma.j.cn221370-20211230-00376", "title": "基于同伴支持的延续护理模式对直肠癌永久性结肠造口术患者的效果", "author": "李辉, 吴艳芳", "keyword": "同伴支持, 延续护理, 直肠癌, 永久性结肠造口术", "abstract": "目的 探讨基于同伴支持的延续护理模式对直肠癌永久性结肠造口术患者的效果。方法选取2019年7月至2021年6月烟台市烟台山医院收治的直肠癌永久性肠造口术患者120例为研究对象，根据随机数字表法将其分为传统组和研究组各60例。传统组实施常规护理，研究组实施基于同伴支持的延续护理模式，观察并比较两组患者自我管理能力、自我护理能力及造口并发症发生情况。结果研究组自我管理能力评分、自我护理能力评分均显著优于传统组，研究组并发症发生率显著低于传统组（P<0.05）。结论基于同伴支持的延续护理可有效改善患者自我管理行为，显著提升患者自我护理能力，降低并发症发生风险，该护理可为永久性肠造口术患者居家康复质量提供持续性保障。", "pub_time": "2023"}
{"sha256": "366d66cbf765f2e680c58baffe4312c080e5055d36b62b62f7954066c745b798", "doi": "", "title": "以高质量发展为主题的时代特征与价值", "author": "黄泰岩, 杨杰东", "keyword": "", "abstract": "", "pub_time": "2021"}
{"sha256": "d7fbc346e33ce643daad58ef5b1ed941c4663df56c9c6d55025937898e93bffc", "doi": "10.3969/j.issn.2096-059X.2021.01.016", "title": "环境信息披露研究主题及其动态演变 ——基于 CiteSpace 的知识图谱分析", "author": "张俭, 何依琳", "keyword": "环境信息披露, CiteSpace, 知识图谱", "abstract": "：基于WOS和CSSCI核心数据库历年文献，采用CiteSpace软件绘制国内外环境信息披露研究领 域知识图谱，探讨发现，环境信息披露研究主题热点及其动态演变，随着时间的推移，环境信息披露研究越 来越受重视：国外研究更注重商业合法性和企业可持续发展主题，国内则主要把重污染行业上市公司作为研 究对象，并注重市场化进程的影响。近期的研究前沿表明，国外不断探索环境信息披露与财务绩效的关联性， 国内研究则偏向于政治因素和绿色金融方向。", "pub_time": "2021"}
{"sha256": "d80a928e89b5880c7dd1df2dd30033b8423052c759e4f8e775ff749886f8a6c1", "doi": "10.3969/j.issn.1008-9993.2022.01.006\n", "title": "运动恐惧在急性心肌梗死经皮冠状动脉介入治疗术后患者自我效能与运动依从性间的中介效应", "author": "任鹏娜, 张月, 丁琳, 汤爱玲, 董里, 葛颜, 袁红艳, 许方蕾, 朱张逸", "keyword": "急性心肌梗死, 经皮冠状动脉介入治疗, 自我效能, 运动恐惧, 运动依从性, 中介效应 ", "abstract": "　目的　探讨运动恐惧在急性心肌梗死经皮冠状动脉介入治疗(percutaneouscoronaryintervention,PCI)术后患者自我效 能与运动依从性间的中介效应.方法　采用便利抽样法,于２０２１年５－８月选取上海２所医院心内科急性心肌梗死行PCI术的 ４３５例患者,采用心脏病患者运动恐惧量表、运动自我效能量表、运动依从性量表对其进行调查.结果　急性心肌梗死PCI术后 患者运动依从性总分为(１．９８±１．１０)分,处于中等水平;自我效能与运动依从性呈正相关(r＝０．５１１,P＜０．０１),运动恐惧与自我效 能、运动依从性呈负相关(r＝－０．２７、－０．５０１;均P＜０．０１).中介模型显示,自我效能对运动依从性存在直接正向预测作用,运动 恐惧在自我效能与运动依从性间起部分中介效应,贡献率为２５．０５％.结论　自我效能可通过运动恐惧间接影响急性心肌梗死 PCI术后患者运动依从性,医护人员应采取系统化措施降低患者的运动恐惧程度,增强其自我效能,进而提高运动依从性. 【关键词】　急性心肌梗死;经皮冠状动脉介入治疗;自我效能;运动恐惧;运动依从性;中介效应", "pub_time": "2022"}
{"sha256": "6b6e080175e5e2883d56a9e468b582062ddbb90c56266c0f30590a0f194a914d", "doi": "10.3760/cma.j.cn221370-20220727-01055", "title": "感染预防护理对牙髓炎椅旁护理感染及满意度的影响", "author": "石志岩, 李申, 付素伟", "keyword": "感染预防, 护理, 牙髓炎, 椅旁护理", "abstract": " 探讨感染预防护理对牙髓炎椅旁护理感染情况及满意度的影响。方法 选择河南省人 民医院2018年6月至2020年10月符合纳入标准且自愿参加该项研究的需行牙髓炎根管治疗的患者为研究对 象，共98例。随机数字法均分为两组，对照组49例，观察组49例，对照组采用常规椅旁护理，观察组在对照组基 础上采用感染预防护理。综合观察患者护理期间的治疗依从性、院内感染的发生情况、焦虑、抑郁情况、护理满意 度。结果 观察组患者治疗总依从率87.76%（43/49），优于对照组的71.43%（35/49），差异有统计学意义（Z= 4.021,P=0.045）。观察组患者院内感染的总发生率4.18%（2/49），低于对照组的16.33%（8/49），差异有统计 学意义(X²=4.009,P=0.045）。两组焦虑、抑郁、心率干预前比较差异无统计学意义（P>0.05）；干预后，观察组 焦虑（43.24±4.21)分显著低于对照组（54.53±4.63）分，差异有统计学意义（t=12.629、P<0.001）；观察组抑郁 （44.64±3.63）分显著低于对照组（53.52±4.04）分，差异有统计学意义（t=11.445、P<0.001）；观察组心率 （100.24±9.53）次显著低于对照组（110.53±12.46）次，差异有统计学意义（t=4.598、P<0.001）。观察组护理满 意度93.88%（46/49），高于对照组的79.59%（39/49），差异有统计学意义（x²=4.346,P0.037）。结论仑感染预 防护理能显著降低牙髓炎椅旁护理的院内感染发生情况，一定程度上提高患者根管治疗的效率，缩短手术时间和 术后疼痛，有利于建立良好的护患关系，提高患者的满意度，值得推广。", "pub_time": "2023"}
{"sha256": "6b4c7595f9c83639ec6016f873d69e7322f3d7d18a530d13de3d3873c2656658", "doi": "10.1088/1367-2630/aa70af", "title": "Twinned-domain-induced magnonic modes in epitaxial LSMO/STO films", "author": "Erik Wahlström, Ferran Macià, Jos E Boschker, Åsmund Monsen, Per Nordblad, Roland Mathieu, Andrew D Kent, Thomas Tybell", "keyword": "magnonics, epitaxial LSMO/STO films, FMR, twin domains", "abstract": "The use of periodic magnetic structures to control the magneto-dynamic properties of materials— magnonics—is a rapidly developing field. In the last decade, a number of studies have shown that metallic films can be patterned or combined in patterns that give rise to well-defined magnetization modes, which are formed due to band folding or band gap effects. To explore and utilize these effects in a wide frequency range, it is necessary to pattern samples at the sub-micrometer scale. However, it is still a major challenge to produce low-loss magnonic structures with periodicities at such length scales. Here, we show that for a prototypical perovskite, La0.7 Sr0.3 MnO3, the twinned structural order can be used to induce a magnetic modulation with a period smaller than 100 nm, demonstrating a bottom-up approach for magnonic crystal growth", "pub_time": "2017"}
{"sha256": "001010e945e5c439bbb55d2283bb128b21ba6bdda5cdf90a0d968dac17123408", "doi": "10.1149/2162-8777/abe8b4", "title": "Review—Brief Review of the Solid-State Graphenothermal Reduction for Processing Metal Oxide-Reduced Graphene Oxide Nanocomposites for Energy Applications", "author": "Harita Pant, Shaikshavali Petnikota, Venkata Satya Siva Srikanth Vadali", "keyword": "", "abstract": "In the recent past, metal oxide (MO)-reduced graphene oxide (rGO) nanocomposites have attracted great attention in energy applications, especially as active electrode materials in Li-ion batteries and supercapacitors. These nanocomposites are specifically designed to simultaneously tap the properties of metal oxide and graphene, making them advantageous for energy applications. The processing methods of MO-rGO nanocomposites can be broadly classified into i) rudimentary combustion, ii) post-immobilization, and ii) in situ bonding methods. Herein, the only solid-state in situ bonding method named Graphenothermal Reduction (GTR) in preparing various MO-rGO nanocomposites is reviewed. In the GTR method, the catalytic ability of carbon is used in processing the MO-rGO nanocomposites. The carbon in the starting graphenaceous material (typically GO) lowers the activation energy of the reduction reaction (which also lowers the reduction temperature) to in situ form metal oxide while the starting GO reduces to rGO in the nanocomposite. Immediate future perspectives pertaining to the GTR method are also discussed.", "pub_time": "2021"}
{"sha256": "359729bdc3459d7c987d062116c2eb674baff9ddb75c039feece6247852ef56a", "doi": "10.3847/1538-4357/ac3cb7", "title": "Relativistic X-Ray Reflection Models for Accreting Neutron Stars", "author": "Javier A. García, Thomas Dauser, Renee Ludlam, Michael Parker, Andrew Fabian, Fiona A. Harrison, Jörn Wilms", "keyword": "", "abstract": "We present new reflection models specifically tailored to model the X-ray radiation reprocessed in accretion disks around neutron stars, in which the primary continuum is characterized by a single-temperature blackbody spectrum, emitted either at the surface of the star or at the boundary layer. These models differ significantly from those with a standard power-law continuum, typically observed in most accreting black holes. We show comparisons with earlier reflection models and test their performance in the NuSTAR observation of the neutron star 4U 1705−44. Simulations of upcoming missions such as XRISM-Resolve and Athena X-IFU are shown to highlight the diagnostic potential of these models for high-resolution X-ray reflection spectroscopy. These new reflection models xillverNS, and their relativistic counterpart relxillNS, are made publicly available to the community as an additional flavor in the RELXILL suite of reflection models.", "pub_time": "2022"}
{"sha256": "6b64914649fe8eed0a57aa59d4fab3e9fed2f67394d62248f2e2d95626e8294e", "doi": "10.1088/2053-1591/ac608d", "title": "Experimental investigation on multi-layered filament wound basalt/ E-glass hybrid fiber composite tubes", "author": "K Thirumavalavan, D Sarukasan", "keyword": "Multi layered hybrid fiber composite, Filament winding technique, Mechanical properties, Basalt fiber composite, Microstructure analysis", "abstract": "In this study, the mechanical damage of Basalt/E-glass hybrid fiber-reinforced polymer composite tubes was evaluated experimentally using Micro hardness on transverse direction, uni-directional static tensile loading, and Quasi-static compressive loading. The Burn-off test method has been studied for the volumetric fraction of hybrid composite tubes. The multi-layer hybrid composite tubes composed of eight layers of plies at constant fiber tension of 20N, a constant mandrel rotation speed of 45 RPM and constant winding angle of ±55° for basalt fiber and ±90° for E-glass fiber were fabricated through a 3-axis filament winding machine with a seamless amalgamation of the stage by stage curing in the furnace. Eleven tube arrangements with fiber content proportion of {100%, 25:75%, 50:50% and 75:25%} with various stacking sequence were studied. The test results provide that these mechanical property’s behavior was moderately affected by the proportion of fiber content and most of the time affected by the variation of layer stacking sequence. Adding 50% of basalt and 50% E-glass fiber sharing of BGH7 hybrid combination of basalt laminate placed in the outer side increases the mechanical characterization compared to the 25% and 75% sharing of basalt and E-glass fiber. The fractured fibrous matrix of the tensile specimens and compressive specimens was assessed using a scanning electron microscope (SEM).", "pub_time": "2022"}
{"sha256": "6b7286c3047f87fa600b5edf23af714e0597ddd5f3ebf9943f4bdd180ad1479b", "doi": "10.1088/2632-2153/acab4c", "title": "Convolutional neural network analysis of x-ray diffraction data: strain profile retrieval in ion beam modified materials", "author": "A Boulle, A Debelle", "keyword": "x-ray diffraction, strain, convolutional neural networks, machine learning, ion irradiation, ion implantation", "abstract": "This work describes a proof of concept demonstrating that convolutional neural networks (CNNs) can be used to invert x-ray diffraction (XRD) data, so as to, for instance, retrieve depth-resolved strain profiles. The determination of strain distributions in disordered materials is critical in several technological domains, such as the semiconductor industry for instance. Using numerically generated data, a dedicated CNN has been developed, optimized, and trained, with the ultimate objective of inferring spatial strain profiles on the sole basis of XRD data, without the need of a priori knowledge or human intervention. With the example ZrO2 single crystals, in which atomic disorder and strain are introduced by means of ion irradiation, we investigate the physical parameters of the disordered material that condition the performances of the CNN. Simple descriptors of the strain distribution, such as the maximum strain and the strained depth, are predicted with accuracies of 94% and 91%, respectively. The exact shape of the strain distribution is predicted with a 82% accuracy, and 76% for strain levels <2% where the amount of meaningful information in the XRD data is significantly decreased. The robustness of the CNN against the number of predicted parameters and the size of the training dataset, as well as the uniqueness of the solution in some challenging cases, are critically discussed. Finally, the potential of the CNN has been tested on real, experimental, data. Interestingly, while the CNN has not been trained to operate on experimental data, it still shows promising performances with predictions achieved in a few seconds and corresponding root-mean-square errors in the 0.12–0.17 range for a fully automated approach, vs. a 0.06–0.12 range for a classical, human-based, approach that, in turn, requires several tens of minutes to optimize the solution. While the overall accuracy of the CNN has to be improved, these results pave the way for a fully automated XRD data analysis.", "pub_time": "2022"}
{"sha256": "35c5c163388c57e3a377f54f55b8795a0893886e806f46db11bed141c37b3b37", "doi": "10.3847/PSJ/acd348", "title": "Dual-band Fourier-transform Millimeter-wave Spectrometry for In Situ Gas Sensing", "author": "Brian J. Drouin, Deacon J. Nemchick, Ananda Nole, Adrian Tang, Chung-Tse Michael Wu, Neda Khiabani", "keyword": "Millimeter-wave spectroscopy, Molecular spectroscopy, High resolution spectroscopy, Comet surfaces, Space vehicle instruments", "abstract": "The exploration of icy body composition in the solar system has often involved spectroscopic measurements of volatiles detected with remote sensing, such measurements portray materials naturally expelled from the surface that enter the exosphere and potentially escape into space. Variations in the ratio of deuterium and hydrogen in these measurements have led to inconclusive hypotheses regarding potential cometary origins of Earth’s ocean water and/or organics. Observational biases regarding unknown previous processing of the observable ejected materials necessitates studies of more dormant, less-processed bodies. Landed missions on comets have brought focus onto the development of small, sensitive instrumentation capable of similar composition measurements of the nascent surface and near-surface materials. We present an evolution of our compact Fourier-transform millimeter wave cavity spectrometer that is tuned for sensitivity at 80.6 and 183 GHz where HDO and H2O exhibit resonance features. We discuss both a low-SWaP (size–weight and power) architecture that uses custom microchip transceiver elements as well as a modular configuration using traditional GaAs-based millimeter-wave hardware. Newdesign features for these systems including quartz-based coupling elements, system thermal management, and a separable clocking board are discussed in addition to sensitivity studies and applications in potential mission scenarios.", "pub_time": "2022"}
{"sha256": "d69a4a456052c24308a96afc23fe8d39200fe97c4dfdcafb67acb7d9f19a283a", "doi": "10.3847/1538-4357/ac69d5", "title": "Sun-as-a-star Spectroscopic Observations of the Line-of-sight Velocity of a Solar Eruption on 2021 October 28", "author": "Yu Xu, Hui Tian, Zhenyong Hou, Zihao Yang, Yuhang Gao, Xianyong Bai", "keyword": "", "abstract": " The propagation direction and true velocity of a solar coronal mass ejection, which are among the most decisive factors for its geo-effectiveness, are difficult to determine through single-perspective imaging observations. Here we show that Sun-as-a-star spectroscopic observations, together with imaging observations, could allow us to solve this problem. Using observations of the Extreme Ultraviolet Variability Experiment onboard the Solar Dynamics Observatory, we found clear blueshifted secondary emission components in extreme-ultraviolet spectral lines during a solar eruption on 2021 October 28. From simultaneous imaging observations, we found that the secondary components are caused by a mass ejection from the flare site. We estimated the line-of-sight (LOS) velocity of the ejecta from both the double Gaussian fitting method and the red-blue asymmetry analysis. The results of both methods agree well with each other, giving an average LOS velocity of the plasma of ∼423kms−1. From the 304 Å image series taken by the Extreme ultraviolet Imager onboard the Solar Terrestrial Relation Observatory-A (STEREO-A) spacecraft, we estimated the plane-of-sky velocity from the STEREO-A viewpoint to be around 587 kms−1. The full velocity of the bulk motion of the ejecta was then computed by combining the imaging and spectroscopic observations, which turns out to be around 596 km s−1 with an angle of 42°.4 to the west of the Sun Earth line and 16°.0 south to the ecliptic plane.", "pub_time": "2022"}
{"sha256": "6ba64d23ecf07790781ec32f2536b33ae292947acc35c2b9859825eec955d1aa", "doi": "10.1088/1475-7516/2022/07/039", "title": "New constraints on axion-gauge field dynamics during inflation from Planck and BICEP/Keck data sets ", "author": "Paolo Campeti, Ogan Özsoy, Ippei Obata, Maresuke Shiraishi", "keyword": "axions, CMBR experiments, gravitational waves and CMBR polarization, inflation", "abstract": "We present new constraints on spectator axion-U(1) gauge field interactions during inflation using the latest Planck (PR4) and BICEP/Keck 2018 data releases. This model can source tensor perturbations from amplified gauge field fluctuations, driven by an axion rolling for a few e-folds during inflation. The gravitational waves sourced in this way have a strongly scale-dependent (and chiral) spectrum, with potentially visible contributions to large/intermediate scale B-modes of the CMB. We first derive theoretical bounds on the model imposing validity of the perturbative regime and negligible backreaction of the gauge field on the background dynamics. Then, we determine bounds from current CMB observations, adopting a frequentist profile likelihood approach. We study the behaviour of constraints for typical choices of the model’s parameters, analyzing the impact of different dataset combinations. We find that observational bounds are competitive with theoretical ones and together they exclude a significant portion of the model’s parameter space. We argue that the parameter space still remains large and interesting for future CMB experiments targeting large/intermediate scales B-modes. ", "pub_time": "2022"}
{"sha256": "003b4d5f1d991e3dd0e0d445e351ed8c40ab73b07c8d92a6495f3be0388d7435", "doi": "10.1088/2043-6262/2/3/035003", "title": "Magnetic heating characteristics of La₀.₇SrₓCa₀.₃₋ₓMnO₃ nanoparticles fabricated by a high energy mechanical milling method", "author": "Hung Manh Do, Hong Nam Pham, Van Chien Nguyen, Thi Bich Hoa Phan, Dai Lam Tran, Anh Tuan Nguyen, Quoc Thong Phan, Van Hong Le, Xuan Phuc Nguyen", "keyword": "magnetic inductive heating, hyperthermia, manganite, reactive milling method", "abstract": "Magnetic inductive heating (MIH) of nanoparticles (NPs) attracts considerable research attention, first because of its application to hyperthermia in biological tissues. Most reports so far have dealt with magnetite NPs with a Curie temperature, TC, of as high as above 500 °C. In this paper, we present results of a MIH study in an ac field of frequency 219 and 236 kHz and strength of 40–100 Oe for several samples of La₀.₇SrₓCa₀.₃₋ₓMnO₃ NPs of TC in the region of hyperthermia, that is some tens of degrees above human body temperature. The particle materials were fabricated by a high energy mechanical milling method combined with calcining at various temperatures in the range of 600–900 °C. The heating temperatures of the samples were observed to saturate at a field irradiating time of less than 10 min and at temperatures ranging from 40 to 75 °C depending on the strontium content, the NP concentration, c, and the field parameters. A sudden change in heating rate was clearly revealed in several heating curves for the case of low applied field and low c, which was considered to be related to the onset of a strong decrease in zero-field cooling (ZFC) magnetization of NPs. The initial temperature increase slope, dT/dr, and the saturation temperature, Ts will be analyzed as dependent on the NP concentration. Field dependences of the specific loss power will be analyzed and discussed for various concentrations, c. Evidence of fluid viscosity influence will also be noted.", "pub_time": "2011"}
{"sha256": "003df86367ed0995c5b5ec9aa96521962126fd1b25e1a369c621524f39ee019e", "doi": "10.1088/1367-2630/15/6/063009", "title": "Entanglement and analytical continuation: an intimate relation told by the Riemann zeta function ", "author": "C Feiler, W P Schleich", "keyword": "", "abstract": " We propose measurements on a quantum system to realize the Riemann zeta function ζ. A single system, that is classical interference, suffices to create the Dirichlet representation of ζ. In contrast, we need measurements performed on two entangled quantum systems to extend ζ into the critical strip of complex space where the non-trivial zeros of ζ are located. As a consequence, we can view these zeros as a result of a Schr¨ odinger cat which is by its very construction similar to, but in its details very different from, the superposition formed by two coherent states of identical amplitudes but opposite phases. This interpretation suggests that entanglement in quantum mechanics is the analogue of analytic continuation of complex analysis", "pub_time": "2013"}
{"sha256": "42e3b9c89bd994cb886d061f532d27a38ba1e395b44265728a4814430ad4f16b", "doi": "10.12267/j.issn.2096-5931.2023.10.001", "title": "超高速大容量光传输系统关键技术与产业发展研究", "author": "刘宇旸, 闫飞, 冯立鹏, 吕凯, 冯振华, 陈欢", "keyword": "超高速大容量光传输, 光纤通信系统;单波速率, 扩展波段, 新型光纤", "abstract": "随着互联网新兴业务的兴起,数据流量迎来了爆炸式增长。 围绕超高速大容量光传输系统中的超高速单波技术、扩展波段技术与新型光纤技术,详细介绍了其关键技术、发展现状以及相关产业发展情况,并对超高速大容量光传输系统关键技术与产业的未来发展方向进行了展望。", "pub_time": "2023"}
{"sha256": "0ffd0920eacfacec15d26762958e3e417b0af1c461a572a564560826c1bc651c", "doi": "10.12267/j. issn.2096-5931.2023.10.008", "title": "面向自智光网络的数字孪生技术研究及示范应用", "author": "匡立伟, 曾至诚, 韵湘, 邹菲", "keyword": "光传送网络;智慧光网络;数字孪生;仿真建模", "abstract": ":信息通信技术处于加速融合、系统创新和智能引领的重大变革期,基于数字孪生技术构建具备自 配置、自优化、自修复能力的自智光网络,实现光网络规划、建设、维护、优化、运营全生命周期智能化、自 动化已经成为研究热点。 全面分析数字孪生技术国内外研究现状,提出新型自智光通信网络体系架构, 设计基于高维空间的光网数据量化表示模型,构建完备的数字孪生仿真建模运算集合,并针对当前光网 络运维挑战梳理出三类数字孪生应用场景;利用光网传输质量评估和自动优化案例阐述数字孪生技术 的应用效果,并对数字孪生技术进行总结与展望。", "pub_time": "2023"}
{"sha256": "b54c58d41b4374deffeddb1799a799ae79d237c540ae9c50df6452669122ca2b", "doi": "10.12267/j.issn.2096-5931.2023.11.012", "title": "基于微服务架构的数字孪生仿真平台设计方法", "author": "高月红, 张吉, 严靖炜, 刘奕彤, 郑青碧", "keyword": "微服务, 数字孪生, 仿真\n", "abstract": "提出了一种基于微服务架构的数字孪生仿真平台的设计方法,以多维度资源精准调配的网络节能优化场景为例,通过拆分平台中松耦合的仿真单元,设计通信接口,并基于 Docker 及 Kubernetes 平台实现微服务仿真组件的部署,完成数字孪生仿真平台的架构升级。 通过融合微服务架构的优势,可以为平台未来的升级改造、功能扩展、部署实施等提供便捷。 测试结果表明,该方法可以以容器的形式实现并行计算,在计算量较大的场景下,显著缩短平台运行时间。", "pub_time": "2023"}
{"sha256": "ded078aa8878e34b0747d31875e7cbc28ae6c9b0d5103759d068d1681ad2e079", "doi": "10.12267/j.issn.2096-5931.2023.11.003", "title": "一种面向标识公共递归解析节点的数据安全加固策略", "author": "刘文军, 陈晨, 狄航", "keyword": "工业互联网, 标识解析, 安全加固, 二级节点", "abstract": "为解决工业互联网标识解析体系公共递归解析节点信息透明、缺乏隐私数据保护和身份权限管理等问题,提出了一种面向标识公共递归解析节点的数据安全加固策略。 通过设计加密机制及细粒度权限查验机制,实现了标识解析二级节点的编码注册和解析服务的安全加固,提高了标识解析数据共享的安全性,验证了该方案的有效性。", "pub_time": "2023"}
{"sha256": "2587833944b2668bb12734960450c86048055d5525f214da640f92b564829eaa", "doi": "", "title": "超宽光通信技术及产业趋势", "author": "张成良", "keyword": "超宽光通信；超高速大容量光传输系统；光纤到房间；超高速 PON；光网络开放解耦；WDM PON；自由空间光通信技术", "abstract": "", "pub_time": "2023"}
{"sha256": "3597a3aadc6e8294542c2e92a04755c82d92cee4e1b42de24622e789ff4c0ae1", "doi": "", "title": "REASONING WITH IMPERATIVES USING CLASSICAL LOGIC ", "author": "Joseph S. Fulda", "keyword": "Imperatives; Classical logic; Declaratives; Sanction; Translation scheme; Argument validity", "abstract": "Traditionally, imperatives have been handled with deontic logics, not the logic of propositions which bear truth values. Yet, an imperative is issued by the speaker to cause (stay) actions which change the state of affairs, which is, in turn, described by propositions that bear truth values. Thus, ultimately, imperatives affect truth values. In this paper, we put forward an idea that allows us to reason with imperatives using classical logic by constructing a one-to-one correspondence between imperatives and a particular class of declaratives.", "pub_time": "1995"}
{"sha256": "35a9b907000e6e3425f63fe13569fda38ce3170153d8eaf01a405b46197e99a8", "doi": "", "title": "Different Views of Laws of Nature", "author": "ÖMER FATİH TEKİN", "keyword": "Laws of Nature, regularity theory, nomic necessitation, dispositional essentialism", "abstract": "There are roughly two main understanding in philosophy of science: Epistemology of Science and Metaphysics of Science. It is ex amined that some concept such as Laws of Nature, Causation, Time and Space into the metaphysics of Science. In this paper, it has been studied laws of nature which is one the most important subjects in metaphysics of science. Let’s think outside the box, there are three significant views about laws of nature; Regularity Theory, Necessita tion Theory and Dispositional Essential views. It has been worked the views of David Lewis in regularity theory. In the section of nomic ne cessitation we have been scrutinised the arguments put forward by David Armstrong and finally the last section; it has been discussed Al exander Bird’s views of dispositional essentialism comparing with the other two aspects.", "pub_time": "2017"}
{"sha256": "a0fa7f68abe8c4f4c2df69661ad0ef5c94889be8ccab475d0b860588547bb8bc", "doi": "10.1017/S0003055419000431", "title": "Feminist Trouble: Intersectional Politics in Post-Secular Times", "author": "Éléonore Lépinard", "keyword": "Feminism；Intersectionality；Femonationalism；Sexcularism；Male Privilege；Misogyny；Relational Cosmopolitanism；Patriarchy", "abstract": "", "pub_time": "2021"}
{"sha256": "6b3ec01c572f9061785e6bfbe51429d0b1ef014f7226a3243e8e4fcdaabecba2", "doi": "10.1177/0090591706297714", "title": "The Rights of the Guilty : Punishment and Political Legitimacy", "author": "Corey Brettschneider", "keyword": "punishment, legitimacy, contractualism, criminal justice, rights\n", "abstract": "In this essay I develop and defend a theory of state punishment within a wider conception of political legitimacy. While many moral theories of punishment focus on what is deserved by criminals, I theorize punishment within the specific context of the state’s relationship to its citizens. Central to my account is Rawls’s “liberal principle of legitimacy,” which requires that all state coercion be justifiable to all citizens. I extend this idea to the justification of political coercion to criminals qua citizens. I argue that the liberal principle of legitimacy implicitly requires states to respect the basic political rights of those who are guilty of committing crimes, thus prohibiting capital punishment.", "pub_time": "2007"}
{"sha256": "6b41c5887b15e50aa99d893ba47e378951dc66fdecab61055d4dc1805b41c5e6", "doi": "", "title": "Drug legalization；Drug prohibition；Decriminalization；Harm reduction；Paternalism；Consequentialism；Contractualism；Victim-less crimes", "author": "Kalle Grill", "keyword": "", "abstract": "", "pub_time": "2005"}
{"sha256": "0008a89552c7ed3bb7d44b40f19169b09767c04cdcb084dca916aa1d8f239af7", "doi": "", "title": "Extension of the picture-superiority effect over multiple lists", "author": "RONALD BARNHART, ARTHUR GLENBERG", "keyword": "", "abstract": "In general, pictures are freely recalled better than words, but results of a pilot experiment in dicated that this picture-superiority effect diminished with successive lists. We report here an experiment in which we investigated how the diminution over lists would respond to manipula tion of rate of presentation and list length. Although the diminution over lists did not replicate, the experiment serves to extend the generality of the picture-superiority effect. ", "pub_time": "1990"}
{"sha256": "35ac353189a2eda235a00f4ee543b13e5e69015882d86ce27f9b63522771f032", "doi": "10.1080/13642819108207592", "title": "Bond ordering in amorphous Si₁₋ₓNₓ ", "author": "S. J. Gurman", "keyword": "", "abstract": "We describe the application of a standard thermodynamic model, the quasi-chemical approximation, to the problem of bond arrangement in amorphous Si₁₋ₓNₓ and use it to interpret X-ray photoelectron spectroscopy data to obtain the distribution of nitrogen atoms in this material. We find that, although amorphous Si₁₋ₓNₓ is chemically ordered in the sense that nitrogen atoms are coordinated only by silicon atoms, the nitrogen atoms are distributed essentially randomly throughout the sample.\n", "pub_time": "1991"}
{"sha256": "35ac57da1bbbb9d532fb39bdfadd31fc6a37f12e725856c7ba212d691c9c07f2", "doi": "10.1016/j.suc.2004.06.017", "title": "Professionalism in the match process: the rules and ethics of recruitment", "author": "Karen R. Borman", "keyword": "", "abstract": "The portal through which most allopathic medical students enter graduate surgical education programs in the United States is the National Resident matching Program (NRMP) process, known as ‘‘the match.’’ Recently, the match has come under intense scrutiny, as the NRMP defends itself against a class action, antitrust lawsuit. In this article, I review the structure of the match, discuss available data about match participant behaviors, examine the ethical linkages inherent in the match, and make suggestions to strengthen the professional and ethical framework of the match.", "pub_time": "2004"}
{"sha256": "35ac595bb814158b33e0a2dd0d30721a0e2fb4e3bdc0fa52efb621ca52289bc8", "doi": "", "title": "A SCIENCE CLUB THAT HAD A FUTURE", "author": "CARROL C. HALL", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35ac5d0026607b2ed788ee47a7904ca3e18a2e0cd919cc65c33ab7f16ef1319c", "doi": "10.1016/j.aquaculture.2010.02.006", "title": "Survival, growth, sexual maturity and tissue histamine accumulation of the mysis, Neomysis awatschensis and N. japonica Nakazawa, fed histamine supplemented diets", "author": "Xiaozhen Yang, Jinfeng Wang, Peng Fan, Liulan Zhao, Yongxu Cheng, Xugan Wu, Chaoshu Zeng", "keyword": "Dietary histamine concentration, Neomysis awatschensis, Neomysis japonica Nakazawa, Survival, Sexual maturity, Tissue histamine level", "abstract": " Estuaries are often subjected to intensive aquaculture activities. Finfish and crustacean culture frequently involve the use of trash fish, which can contain high amounts of histamine. This has the potential to be a major ecological concern since this trash fish often becomes a feed source for naturally occurring small aquatic animals, such as mysis. The present study evaluated the effects of dietary histamine supplementation on survival, growth, sexual maturity and tissue accumulation of two estuarine mysis, Neomysis awatschensis and N. japonica Nakazawa. Both N. awatschensis and N. japonica Nakazawa were fed specially formulated diets containing 0 (control), 1, 2 and4g/kg supplemented histamine (5 replicates per treatment; 110 neonates per replicate) from the time they became capable of effectively feeding on formulated diets (10 and 17 day-post-hatch for N. awatschensis and N. japonica Nakazawa, respectively). The feeding experiment continued until the mysis reached sexual maturity. Our current findings indicate that dietary histamine had negative effects on both mysis species although their sensitivity to histamine appeared to be species-specific. Results showed that survival was significantly lower for N. awatschensis fed diet containing 4 g/kg supplemented histamine (56.8%) when compared to that of the control (78.3%), while for N. japonica Nakazawa, survival was significantly lower in both 2 (52.1%) and 4g/kg (51.5%) histamine treatments than in the control group (74.3%) (pb0.05). Histamine containing diets also significantly impacted body length of sexual matured N. japonica Nakazawa, however,nosignificantdifferencesoneitherbodyweightorlengthweredetectedforN.awatschensis(pN0.05).It generally took longer for both males and females of the two mysis species to reach sexual maturity when they were fed diets containing higher levels of histamine and the differences were often significant (pb0.05). Compared to the control, the whole tissue histamine concentration increased significantly for N. japonica Nakazawa fed diets containing 2 and 4g/kg supplemented histamine (pb0.05), however, no significant differences in tissue histamine levels were found among all treatments for N. awatschensis. These results suggest that the consumption of stale aquaculture feeds containing histamine could significantly impact naturally existing aquatic animals that play an important role in the marine food web and ecosystem.", "pub_time": "2010"}
{"sha256": "35ac6c37e764345cea404dabb9fb4390f6eff62611d6aa39473eca75671a3576", "doi": "10.3390/en4040599", "title": "A Smart Online Over-Voltage Monitoring and Identification System ", "author": "Jing Wang, Qing Yang, Wenxia Sima, Tao Yuan, Markus Zahn", "keyword": "smart grid, over-voltage, identification, S-transform, fuzzy expert system", "abstract": "This paper proposes a complete and effective smart over-voltage monitoring and identification system. In recent years, smart grids are of the greatest interest in power system research. One of the main features of smart grid is their self-healing, which can continuously carry out online self-evaluation, discover existing faults, and correct them immediately. The over-voltage smart monitoring-identification-suppression systems play a key role in the construction of self-healing grids. In this paper, eight kinds of common over-voltage are discussed and analyzed. The S-transform algorithm is used to extract features of over-voltage. Aiming at the main features of each kind of over-voltage, six different characteristic quantities are proposed. A well designed fuzzy expert system and a support vector machine are employed as the classifiers to build a two-step identification model. The accuracy of the identification system is verified by field records. Results show that this system is feasible and promising for real applications. ", "pub_time": "2011"}
{"sha256": "35ac7c2a36e1855c258896fe0faf8af48c178c3b88d26af01c825a98b4e059db", "doi": "", "title": "Интервью с Сергеем Грибачевым, генеральным директором «Скани-Рус»", "author": "", "keyword": "«Скани-Рус»；Texas Instruments (TI)；цифровые сигнальные процессоры (ЦСП)；продвижение продукции；дистрибьюторский договор；радиочастотная идентификация；автомобильная электроника", "abstract": "", "pub_time": "2000"}
{"sha256": "6b5966c52a5bb34008c048d36cf68375a4cba0f4e8e269f113062f447649246c", "doi": "10.5281/zenodo.10907366", "title": "Rules for dissipationless topotronics", "author": "Qing Yan, Hailong Li, Hua Jiang, Qing-Feng Sun, X. C. Xie", "keyword": "", "abstract": "Topological systems hosting gapless boundary states have attracted huge attention as promising components for next-generation information processing, attributed to their capacity for dissipationless electronics. Nevertheless, recent theoretical and experimental inquiries have revealed the emergence of energy dissipation in precisely quantized electrical transport. Here, we present a criterion for the realization of truly no-dissipation design, characterized as $ N_{\\text{in}} = N_{\\text{tunl}} + N_{\\text{bs}} $, where $ N_{\\text{in}} $, $ N_{\\text{tunl}} $, and $ N_{\\text{bs}} $ represent the number of modes participating in injecting, tunneling, and backscattering processes, respectively. The key lies in matching the number of injecting, tunneling, and backscattering modes, ensuring the equilibrium among all engaged modes inside the device. Among all the topological materials, we advocate for the indispensability of Chern insulators exhibiting higher Chern numbers to achieve functional devices and uphold the no-dissipation rule simultaneously. Furthermore, we design the topological current divider and collector, evading dissipation upon fulfilling the established criterion. Our work paves the path for developing the prospective topotronics.\n", "pub_time": ""}
{"sha256": "d6e8b2ee1b5665b47e97fad2859f1076129be858ac8c65474c92ff34b9dcbed7", "doi": "", "title": "EFFECTIVE SUPPORT, DIRAC COMBS, AND SIGNAL RECOVERY", "author": "G. GARZA, K. GUREVICH, A. IOSEVICH, A. MAYELI, K. NGUYEN, N. SHAFFER", "keyword": "", "abstract": " Let f : Zd N → C be asignal with the Fourier transform f : Zd N → C. A classical result due to Matolcsi and Szucs ([10]), and, independently, to Donoho and Stark ([3]) states if a subset of frequencies {f(m)}m∈S of f are unobserved due to noise or other interference, then f can be recovered exactly and uniquely provided that |E| · |S| < Nd 2 , where E is the support of f, i.e., E = {x ∈ Zd N : f(x)= 0}. In this paper, we consider signals that are Dirac combs of complexity γ, meaning they have the form f(x) = γ i=1ai1Ai (x), where the sets Ai ⊂ Zd N are disjoint, ai are complex numbers, and γ ≤ Nd. We will define the concept of effective support of these signals and show that if γ is not too large, a good recovery condition can be obtained by pigeonholing under additional reasonable assumptions on the distribution of values. Our approach produces a non-trivial uncertainty principle and a signal recovery condition in many situations when the support of the function is too large to apply the classical theory", "pub_time": "2024"}
{"sha256": "d6e9cca5c647a315c915654205cb37367bdf8416198eca5766e710ed3eec7ad5", "doi": "", "title": "VesselSAM: Leveraging SAM for Aortic Vessel Segmentation with LoRA and Atrous Attention", "author": "Adnan Iltaf, Rayan Merghani Ahmed, Zhenxi Zhang, Bin Li, Shoujun Zhou", "keyword": "SAM, Parameter efficient fine-tuning, LoRA, Atrous attention, Aortic vessel segmentation", "abstract": " Medical image segmentation is crucial for clinical diagnosis and treatment planning, especially when dealing with complex anatomical structures such as vessels. However, accurately segmenting vessels remains challenging due to their small size, intricate edge structures, and susceptibility to artifacts and imaging noise. In this work, we propose VesselSAM, an enhanced version of the Segment Anything Model (SAM), specifically tailored for aortic vessel segmentation. VesselSAM incorporates AtrousLoRA, a novel module integrating Atrous Attention and Low-Rank Adaptation (LoRA), to enhance segmentation performance. Atrous Attention enables the model to capture multi-scale contextual information, preserving both fine-grained local details and broader global context. Additionally, LoRA facilitates efficient fine-tuning of the frozen SAM image encoder, reducing the number of trainable parameters and thereby enhancing computational efficiency. We evaluate VesselSAM using two challenging datasets: the Aortic Vessel Tree (AVT) dataset and the Type-B Aortic Dissection (TBAD) dataset. VesselSAM achieves state-of-the-art performance, attaining DSC scores of 93.50%, 93.25%, 93.02%, and 93.26% across multi-center datasets. Our results demonstrate that VesselSAM delivers high segmentation accuracy while significantly reducing computational overhead compared to existing large-scale models. This development paves the way for enhanced AI-based aortic vessel segmentation in clinical environments. The code and models will be released at https://github.com/Adnan-CAS/AtrousLora", "pub_time": "2025"}
{"sha256": "d6f0c6a9834ac17e288047b3c4583d43be24edece229ab51dcd7085d8ee04578", "doi": "", "title": "Distributed Computing for Huge-Scale Linear Programming", "author": "Luoyi Tao", "keyword": "", "abstract": " This study develops an algorithm for distributed computing of linear programming problems of huge-scales. Global consensus with single common variable, multiblocks, and augmented Lagrangian are adopted. The consensus is used to partition the constraints of equality and inequality into multi-consensus blocks, and the subblocks of each consensus block are employed to partition the primal variables into M sets of disjoint subvectors. The block-coordinate Gauss-Seidel method, the proximal point method, and ADMM are used to update the primal variables, and descent models used to update the dual. Convergence of the algorithm to optimal solution is shown and the rate of convergence of the augmented Lagrangian sequence, of O(1/k) is obtained, under the dual sequences supposedly bounded. This boundedness of the dual sequences needs to be ensured through adequate choice of the control parameter values and initialization of the primal and dual sequences; further to help resolve the issue, it is to be explored that explicit bounds are imposed for the dual variables associated with the global consensus equality constraints.", "pub_time": "2025"}
{"sha256": "d6f562d36c867499da89c6994d7f79f1775e2e85f1120203c06845ec81cd112b", "doi": "", "title": "MedVAE: Efficient Automated Interpretation of Medical Images with Large-Scale Generalizable Autoencoders", "author": "Maya Varma, Ashwin Kumar, Rogier van der Sluijs, Sophie Ostmeier, Louis Blankemeier, Pierre Chambon, Christian Bluethgen, Jip Prince, Curtis Langlotz, Akshay Chaudhari\n", "keyword": "", "abstract": " Medical images are acquired at high resolutions with large fields of view in order to capture fine-grained features necessary for clinical decision-making. Consequently, training deep learning models on medical images can incur large computational costs. In this work, we address the challenge of downsizing medical images in order to improve downstream computational efficiency while preserving clinically relevant features. We introduce MedVAE, a family of six large-scale 2D and 3D autoencoders capable of encoding medical images as downsized latent representations and decoding latent representations back to high-resolution images. We train MedVAE autoencoders using a novel two-stage training approach with 1,052,730 medical images. Across diverse tasks obtained from 20 medical image datasets, we demonstrate that (1) utilizing MedVAE latent representations in place of high-resolution images when training downstream models can lead to efficiency benefits (up to 70x improvement in throughput) while simultaneously preserving clinically-relevant features and (2) MedVAE can decode latent representations back to high-resolution images with high fidelity. Our work demonstrates that large-scale, generalizable autoencoders can help address critical efficiency challenges in the medical domain. Our code is available at https://github.com/StanfordMIMI/MedVAE", "pub_time": "2025"}
{"sha256": "28b4852d0fd105e81be9912aed5dc4e4eb2e5e035c5668c0ec159c99200f1a7f", "doi": "10.4236/oalib.1111308", "title": "Visual Design as the Impetus for Access and Utilization of Information in Digital Resource Platforms in University Libraries", "author": "Anne Nakhumicha Tenya, Jane Cherono Maina, Fredrick Mzee Awuor", "keyword": "Visual Design, Access, Digital Resource Platforms, Utilization, University Libraries", "abstract": "The study sought to examine the visual design in digital resource platforms in selected public universities in Kenya. The study adopted a descriptive survey research design. Data was collected from a targeted population comprising of 86 academic staff, 23 library staff in charge of e-content and 4 university li brarians from four selected universities namely: University of Nairobi, Ke nyatta University, Moi University and Egerton University. Questionnaires were administered to academic staff and library staff in charge of e-content while an interview guide was used to gather data from university librarians. Data was analyzed using descriptive statistics, and presented in form of tables, charts and graphs and verbatim reports. Findings showed that the layout of content was unappealing, no clear paths for navigation, use of images and color for attraction was lacking while search features were complicated to understand. The visual design in the digital platforms lacked user considera tion and did not adequately facilitate effective access and utilization of infor mation. The study concludes that visual design is an important component in digital resource platforms for attracting users to access and utilize digital in formation hence the need to develop user-centered platforms.", "pub_time": "2024"}
{"sha256": "7358294d70943a98d7fb6a913ba7b2162ee46b864bf6ca2e97ef1d3524662e17", "doi": "10.4236/oalib.1111259", "title": "A Study of “Profession + Foreign Language” Based Curriculum Design of College English", "author": "Yan Cui", "keyword": "Profession + Foreign Language, College English, ESP, Curriculum Design", "abstract": "Internationalization and globalization require students to have a certain level of foreign language communication ability, so for non-English majors, to have the dual ability of both comparatively high level of foreign languages and knowledge and skills in majors is of significance. The familiarity and mastery of professional related content by students in the general English stage of universities can help them better carry out their subsequent bilingual courses, making them versatile professionals in line with market demand, and thereby enhancing their employment competitiveness. The present study has designed a “profession + foreign language” curriculum which aims for culti vating students’ language proficiency by creating the dynamic system of Eng lish learning. ", "pub_time": "2024"}
{"sha256": "dbd011a0c3e3dc463225314275ae547d69adb1270c16f814a18f0bc72a52f975", "doi": "10.4236/oalib.1111271", "title": "Electrocoagulation as a Pretreatment of Electrooxidation for Killing Escherichia coli", "author": "Djamel Ghernaout, Noureddine Elboughdiri", "keyword": "Pathogens, Chemical Coagulation (CC), Electrocoagulation (EC), Electrophoretic Mobility, Natural Organic Matter (NOM)", "abstract": "Although the literature mainly reports on the inactivation of bacteria by var ious electrochemical disinfectants, the impact of process variables and reactor design on bactericidal performance is not fully understood. This review con centrates on recent achievements of electrocoagulation (EC) and electrooxi dation (EO) in killing pathogens such as Escherichia coli. Lynn et al. [1] [2] showed that in addition to EC alone, EC-EO enhanced E. coli reduction only after pH adjustment. They proposed that additional process optimization may lead to further improvements, such as adjusting the iron dosage for nat ural organic matter (NOM) removal, which would limit the effectiveness of oxidant scavengers. Additionally, more efficient filtration techniques (e.g., granular filtration) will reduce NOM and total iron content in the EO feed water, decreasing the need for oxidants. Furthermore, continuous EC-EO treatment requires more elevated EO current densities to improve E. coli re moval. Investigating the pathways of demobilizing E. coli in drinking water at high iron concentrations in the EO range will also provide deep insights into ongoing setup design. This review provides crucial, reliable, safe, and versatile alternatives to the widespread trouble of human drinking water pollution. Using and propagating the EC-EO technique will diminish health risks re lated to water quality, economic burden, lost labor time, import washout to the national economy, and natural resource management. Commercial-scale deployment of EC-EO technology will undoubtedly increase the socioeco nomic burden on local communities via secured water supply and result in a reduction in government health expenditures.", "pub_time": "2024"}
{"sha256": "42549d7f335e66918f21e9a53ce97e55d8455438fb66fb402fa020dadf4314a6", "doi": "10.4236/oalib.1111240", "title": "A Comparative Analysis of Indonesia and China on Managing Cultural Diversity in Multinational Corporations", "author": "Felicia Margaretha Putri", "keyword": "Cultural Diversity, Multinational Corporations, Multinational Firm", "abstract": "This study aims to undertake a thorough comparison analysis, diving into the complexities and consequences of cultural diversity management in Indonesian and Chinese multinational firms. This study aims to provide an in-depth exploration of the diverse strategies employed, challenges encountered, and viable solutions implemented by multinational corporations in both countries as they grapple with the complexities of cultural diversity. By examining the various approaches and outcomes, this research aims to provide significant insights for global multinational corporations, serving as a substantive reference based on a sophisticated comparative analysis. The primary goals include gaining a thorough grasp of cultural diversity management strategies, identifying common issues, and developing practical solutions applicable in a variety of global contexts. The technique includes a thorough assessment of the literature in addition to an in-depth investigation into the business practices of multinational corporations in China and Indonesia. The research’s conclusions have the potential to make a significant contribution to the scholarly conversation about cultural diversity management as well as offer practical advice for multinational firms attempting to negotiate the complexities of many cultural contexts. ", "pub_time": "2024"}
{"sha256": "15ff1e2ce8f09e8b2466f783ef8124f335a8e3d19c9132afd544484812dd27df", "doi": "10.4236/oalib.1111446", "title": "Clinical Audit of Beam Output of Cobalt-60 Teletherapy Unit at AECH-BINOR", "author": "Zahid Khan, Muhammad Usman Ghani, Tooba Mujtaba, Saeed Ur Rehman, Kalim Ullah Khan, Muhammad Maaz, Ali Nawaz Muhammad", "keyword": "Clinical Audit, oBeam Output, Cobalt-60 Teletherapy Unit", "abstract": "Uncontrolled cell development is a hallmark of cancer, a leading cause of death globally. Optimal cancer treatment necessitates the use of multiple methods, including surgery, chemotherapy, and radiation treatment. High-energy radiation in radiotherapy eliminates cancer cells by causing irreparable damage to their DNA (deoxyribonucleic acid). The radiation dose is delivered via a teletherapy unit. Dosimetric quality assurance tests are conducted to ensure accurate and safe radiation delivery. Guidelines for dosimetry are provided by AAPM TG 51 and IAEA TRS 398. We followed the dosimetry protocol of the International Atomic Energy Agency (IAEA) TRS 398. Dosimetry data were collected and evaluated for a period of nine years, beginning in 2014 and ending in 2022. The analysis of dosimetry data from 2014 to 2022 showed that the difference between the measured and calculated dose rate is 1.904 ± 1.41, which is below the IAEA guidelines, i.e., ±2%. The results suggest that dosimetry was in accordance with international protocols. It also reflects that radiation dosimetry is well carried out at BINOR cancer hospital.", "pub_time": "2024"}
{"sha256": "120967251fda4bbedb7c664a7cfb18c5373beb38cf101213eaf33907020d5042", "doi": "10.4236/oalib.1111289", "title": "The Regulation of Metaverse through Crime of Insult and Libel", "author": "Xinlei Yuan, Zhaojin Wang", "keyword": "Metaverse, Personality Rights and Interests, Insult and Defamation, Criminal Law Regulation", "abstract": "With the popularization of decentralized Metaverse communities and the functions within it in future, the stealthiness of information sources and data flow will be greatly enhanced. Besides, in an entertaining and commercial environment, the media will be more diverse and the access to information will be more convenient, fast and comprehensive. Moreover, based on its purpose, the Metaverse is better related to the individual rights and interests of property and personality. Hence, individual’s reputation and portrait would become more important in future life and business communication. Therefore, crime of insult and libel, one of crimes that seriously violate the right of personality, would probably break through the infrequent crime zone in practice and turn into one of popular crimes when the Metaverse becomes widely known like Internet. In our research, premised on the theories about Metaverse and domestic criminal law studies on crime of insult and libel, we analyzed the impact and shock towards legal interest, subject and objective constitutive elements of the considered crime. Finally, we concluded the path of regulation through three aspects: they are explaining existing concept and theory, promulgating Judicial Interpretation includes emerging criminal acts, and formulating and enacting new context in the criminal law conform to the trend of misdemeanor.", "pub_time": "2024"}
{"sha256": "1f90b7e6a258c8704f1b49664f37868ebd8d62e93b271a7bdb19c7f26baf7bc3", "doi": "10.4236/oalib.1111319", "title": "A Systematic Review of the Effects of Soil Stabilization on Soil Mechanical Properties: A Comparative Study of Fly Ash, Cement and Lime", "author": "Duke Magara, Haicheng She", "keyword": "Soil Stabilization, Lime, Cement, Fly Ash, Mechanical Properties", "abstract": "tematic literature review methodology based on the PRISMA guidelines. The review was limited to articles published between 2013 and 2023. From the outcomes of the systematic review, it was found that soil stabilization using either lime, cement or fly ash has significant positive effects on the mechanical properties of soil. Precisely, the results indicated that cement, lime, and fly ash can significantly improve soil mechanical properties such as strength, permeability, and stability. Overall, fly ash was found to be the most effective soil stabilizing agent compared to lime and cement. However, it was concluded that whilst fly ash alone can be more effective in soil stabilization, a combination of cement, lime and fly ash can be more effective. Overall, the research highlighted the potential of different soil stabilizing agents in enhancing the mechanical properties of soils and hence providing valuable insights for geotechnical and civil engineers and practitioners. However, further experimental or field studies are required to comprehensively compare the short-term and long-term impacts of fly ash, cement and lime on soil mechanical properties", "pub_time": "2024"}
{"sha256": "e49a1ee9d67c278c29df80861a79a7c4884247e7422780f2fab8306d7f01cb0b", "doi": "10.4236/oalib.1111340", "title": "A Comparative Study of the Origins of Phonography and Ideograph", "author": "Ge Liu, Chen Chen, Tingting Ye", "keyword": "Ideograph, Phonography, Geography, Phonetics, Philosophy", "abstract": "Human script has gone through a long process and many developments, eventually evolving into two main branches, namely, the ideograph and the phonography. However, the reasons for the separation of ideograph and phonography, as well as the features of the two, have been the subject of much disagreement in the academic community. Taking Chinese characters as an example for ideograph, English, Sumerian cuneiform, and Phoenician as examples for phonography, this article makes a detailed study of the reasons for differences in the origins of ideograph and phonography from the aspects of geography, national concepts of time and space, and phonetic structure.", "pub_time": "2024"}
{"sha256": "118aab542079f4c9a41843702da594af0d7b00ed0ab4df41caa51dc899261ca2", "doi": "10.4236/oalib.1111269", "title": "A New Description of the Advertisement Call of Terrestrial Nebulous Treefrog, Scinax nebulosus (Spix, 1824) in Brazil: Implications for Interpopulation Variation", "author": "José R. de Oliveira-Santos, Geraldo J. B. Moura, Marcelo N. C. Kokubum, Priscila G. Gambale", "keyword": "Anuran, Acoustic Parameters, Advertisement Call, Bioacoustics Diversity, Northeastern Brazil", "abstract": "The genus Scinax encompasses 75 recorded species, making it one of the most abundant within the Hylidae group. Scinax nebulosus, a small terrestrial anuran, is distributed throughout northern South America, between Venezuela, Bolívia and northeastern Brazil. This study aimed to characterize the advertisement call of two distinct populations of Scinax nebulosus (Spix, 1824) in the state of Pernambuco, Brazil. Fieldwork was conducted at the Dois Irmãos State Park and the Camocim forest. The advertisement call of this species consists of a single multipulsed note, lasting 0.3 seconds, with an inter-note interval of 0.9 seconds and a dominant frequency of 3.3 kHz. Temporal and spectral parameters of the Northeast Brazilian populations differ from those in the Amazon. The wealth of bioacoustics information from various populations plays a crucial role in propelling comprehensive research in anuran bioacousti", "pub_time": "2024"}
{"sha256": "abd60458841e74297167d87738495bbb50d0ed87fc49035f31a43ce662c23f75", "doi": "10.4236/oalib.1111294", "title": "Anxiety, Depression, and Associated Factors among Teachers during the COVID-19 Pandemic: A Multi-Centre Cross-Sectional Study in Zambia", "author": "Steward Mudenda, Maisa Kasanga, Scott Kaba Matafwali, Roland Nnaemeka Okoro, Ruth Lindizyani Mfune, Tina Haanyanga, Matildah Nyoni, Annie Mumba, Godfrey Mayoka, Victor Daka, Christabel Nang’andu Hikaambo, Webrod Mufwambi, Shafiq Mohamed, Billy Chabalenge\n", "keyword": "COVID-19, Mental Health, Anxiety, Depression, Secondary Schools, Teachers, Zambia", "abstract": "Background: The coronavirus disease 2019 (COVID-19) pandemic inflicted unprecedented work-related strain, negatively impacting the mental health of many, including teachers. This study assessed the impact of COVID-19 on the mental health of secondary school teachers in Lusaka, Zambia. Materials and Methods: This cross-sectional study was conducted among 388 teachers in selected secondary schools in Lusaka district, Zambia, from July 2022 to September 2022. Data were collected using the Hospital Anxiety and Depression Scale (HADS) and analysed using IBM SPSS version 28.0. Statistical significance was determined at a 95% confidence level. Logistic regression was used to determine the factors that influenced anxiety and depression levels among teachers. Results: Among the 388 teachers, the prevalence of anxiety and depression was 72% and 73%, respectively. Factors associated with anxiety were; being quarantined due to COVID-19 (AOR = 1.96, 95% CI: 1.11 - 3.45), having a chronic condition (AOR = 2.45, 95% CI: 1.19 - 5.05), having a friend or relative with COVID-19 (AOR = 1.8, 95% CI: 1.08 - 2.99) and experiencing death of either a friend or relative (AOR = 2.36, 95% CI: 1.48 - 3.76). Factors associated with depression included; having a friend or relative with COVID-19 (AOR = 2.63, 95% CI: 1.38 - 5.00), experiencing the death of either a friend or relative (AOR = 2.03, 95% CI = 1.16 -3 .54) and suffering income disruptions due to COVID-19 (AOR = 1.65, 95% CI: 1.02 - 2.66). Conclusions: This study found that anxiety and depression were highly prevalent, especially among teachers with predisposing factors. These findings demonstrate the need to develop and implement strategies to tackle mental health challenges among teachers, especially during pandemic periods.", "pub_time": "2024"}
{"sha256": "35e2a7a6c651f72f848a515923d5b2e66536917de4219d8c2677c305509c0bc1", "doi": "", "title": "EFFECTS OF GAMIFICATION: ANALYZING STUDENT ACHIEVEMENT, MASTERY, AND MOTIVATION IN SCIENCE CLASSROOMS", "author": "Annie Lee Reichelt ", "keyword": "", "abstract": "I wanted to implement a teaching model that requires students to obtain mastery of a concept. Students typically understand the premise of games and how games are played. Gamification requires that students master a specific level or learning objective before continuing on in the course. Although gamification is a relatively new model of instruction, it incorporates elements of standards based grading and mastery learning.The purpose of this study was to determine if gamification increased student achievement, student mastery and student motivation. Learning objectives were separated and all class activities centered on leveled learning objectives. Students were not able to test out of a set of learning goals until they had demonstrated mastery of the content. Student test and quiz scores were recorded over a 27-week period. Students took surveys, participated in interviews and discussions as part of the study as well.Results showed there was a significant increase in scores with implementation of gamification. Particular success was shown in non-honors classes rather than honors courses. Student mastery and achievement increased with implementation because students were not allowed to move forward in content if they did not receive at least an 80% on quiz scores. I will continue to adjust and modify this learning model based on the positive outcomes of the study.", "pub_time": "2015"}
{"sha256": "d6c47120e2aab55a9f074da4e7890d0174b96b0e7f07d31ed718906c3b062534", "doi": "", "title": "NITROGEN DYNAMICS OF CENTAUREA MACULOSA AND NATIVE SPECIES ", "author": "Elizabeth Anne D’Imperio", "keyword": "", "abstract": "Centaurea maculosa has invaded millions of hectares of disturbed and undisturbed semi-arid grasslands. Its success may be due to an ability to conserve nitrogen (N) or use N more efficiently than native species. It may also be able to acquire more N from early spring pulses than native vegetation.\nGrowth response, N acquisition, allocation, resorption and use efficiency of C. maculosa was compared with Pseudoroegneria spicata, Pascopyrum smithii, and Rudbeckia hirta by growing plants in high and low N supplies, which mimic disturbed and undisturbed sites. 15Nitrogen acquired per unit of root mass was highest in R. hirta. Centaurea maculosa had the lowest C:N ratio. Resorption proficiency was lower in C. maculosa for Harvest 2 and 3, and similar among all species at Harvest 4. Centaurea maculosa had the highest mean residence time (MRT) and lowest N productivity. Centaurea maculosa had the highest nitrogen use efficiency (NUE) for plants receiving the high N supply whereas NUE was similar for all species receiving the low N supply. Centaurea maculosa’s success in disturbed sites may be due to a high NUE, which can be attributed to a high MRT. \nUptake and growth response of C. maculosa receiving an early spring, late spring or steady N treatment were determined in a glasshouse and a field study. Centaurea maculosa’s response was compared with P. spicata, Festuca idahoensis and R. hirta in the glasshouse, and P. spicata, F. idahoensis and Balsamorhiza sagittata in the field. In the glasshouse, with plants receiving the steady N treatment produced the most biomass whereas plants receiving the late N treatment produced the least. Grasses receiving the early N treatment had the highest root mass ratio (RMR), whereas RMRs of C. maculosa were similar among N treatments. Forbs acquired more N than grasses. In the field, biomass was similar among N treatments. Plants took up more N from the early treatments than the late or steady treatments. Centaurea maculosa may be able to acquire more N from pulses than grasses in disturbed sites when plants are small, but as the grasses grow, C. maculosa may lose its advantage in acquiring N. ", "pub_time": "2005"}
{"sha256": "a106f0a655f530f1899c0df4b34512facdd9494f11db6d81e691dff47373a8dd", "doi": "", "title": "PLACE-BASED AND STUDENT-LED CLIMATE CHANGE INSTRUCTION IN THE SCIENCE CLASSROOM", "author": "Elexa Deidre Rendla", "keyword": "", "abstract": "Climate change is a global problem affecting everyone living on Earth. In Florida specifically, intense hurricanes are becoming a familiar event. In response to this phenomenon, I designed hurricane lessons to help students understand the link between climate change and increased hurricane intensity. I used place-based and student-led lessons. During these lessons, 14 students attended in-person and 16 students attended online, which was an option for students during the Covid-19 pandemic.\nIn the Hurricane Webquest, students learned about the structure of hurricanes, tracked Hurricane Irma and read about the link between rising sea-surface temperatures and hurricane intensity. For the Thermodynamics PhET Labs, students investigated the links between climate and heat, and energy transfer. In the Thermodynamics Mini-Project, students looked at how thermal energy can be converted into kinetic energy in hurricanes. Finally, in the Hurricane Building Codes Assignment, students investigated local buildings and how they met the Florida hurricane building codes.\nBoth before and after the hurricane lessons, students participated in the Hurricane Likert Survey and took a Hurricane Knowledge Test. Some students also participated in final interview questions once the lessons were concluded. Students indicated in both pre-and post-surveys that they were aware of climate change. After the hurricane lessons, students reported a greater understanding of the relationship between climate change and hurricanes. After students completed the Hurricane Building Codes Assignment, they were better able to articulate their reasons for evacuating or staying during a hurricane. When in-person and online students were compared, their greatest difference was in-class participation. Students attending in-person participated in classroom discussion, and those who attended from home stayed silent. ", "pub_time": "2021"}
{"sha256": "a113f8e2c75484cbcf9eb80028abedb8dd336a88717034589d6e9c213cbbd2b3", "doi": "", "title": "FOSTERING NURSING STUDENT RESILIENCE", "author": "Gina Nicole Marquardt", "keyword": "", "abstract": "The purpose of this quality improvement project was to identify components of resiliency and create a solution to develop senior-level nursing student resilience. Assessment of Location X nursing school highlighted the need to identify components, tools, and measures of senior-level nursing student resiliency. The American Association of Colleges of Nursing (AACN) cites the importance of the development of nursing student wellbeing and resilience in the 2021 Essentials Domain 10 titled Personal, Professional and Leadership Development. The AACN further advocated for resiliency development during a 2020 Call to Action of United States nursing programs to promote and create a culture of wellness and resiliency among nursing students. The “Thriving in Nursing School” workshop was developed as a solution to equip students with the necessary tools, practices, and skills to develop resilience. The workshop consists of five evidence-based components: relaxation strategies, coping techniques, communication skills for problem solving, community and university resources available, and faculty mentorship. Formal focus and education about resilience has the potential to increase resiliency skills and was measured using the Connor-Davidson Resilience Scale (CD-RISC-10). It was hypothesized that resiliency-development quality improvement implementation will contribute to further development of nursing students’ resiliency skills to meet the demands of the nursing profession. Through a focus on student wellbeing and resiliency, this project has the potential to increase student success and improve skills to thrive in a rigorous education program. This quality improvement project was implemented to gather data and analyze workshop efficacy. ", "pub_time": "2023"}
{"sha256": "0063fa60f7c61493e1fcc9a1953024a7775f86c9dcac867c73550fdc608cd0f1", "doi": "", "title": "BIODIVERSITY POTENTIAL IN THE PACIFIC AND INLAND NORTHWEST: THE RELATIVE IMPORTANCE OF FOREST STRUCTURE AND AVAILABLE ENERGY IN DRIVING SPECIES DIVERSITY", "author": "Jacob Pieter Verschuyl", "keyword": "Biodiversity; Forest structure; Available energy; Bird species richness (BSR); Pacific and Inland Northwest (PINW); Productivity gradients; Forest management; Structural complexity; Species-energy relationship; Disturbance", "abstract": "Currently, the most common strategy of forest biodiversity managers in the Pacific and Inland Northwest (PINW) is to maintain structural complexity within forest stands and create the full range of seral stages across the landscape. Recent advances in ecological theory reveal that biodiversity at regional to continental scales is strongly influenced by available energy (i.e. factors influencing vegetative growth such as precipitation, temperature, radiation, soil fertility). We hypothesized bird species richness (BSR) exhibits a positive or unimodal relationship with energy across landscapes and the relationship between energy and BSR within a landscape is positive in energy limited landscapes and flat or decreasing in energy rich landscapes. Additionally, we hypothesized that structural complexity explains a lower percentage of the variation in BSR in energy limited environments and higher percentage in energy rich environments and that the slope of the relationship between structural complexity and BSR is greatest in energy rich environments. Ours is the first study to test the relative influence of energy and vegetation structure on BSR at local scales, and to offer predictive theory on how these influences differ across energy gradients. We sampled bird communities and vegetation across a matrix of seral stages and biophysical settings at each of 5 landscapes. We analyzed the response of BSR to structural complexity and energy covariates at each landscape. We found that (1) BSR had a unimodal relationship with available energy across the PINW region, (2) the landscape-scale relationships between energy and BSR were positive or unimodal in energy limited locations and were flat or negative in energy rich locations, (3) forest structural complexity explained more of the variation in bird species richness in energy rich landscapes, and (4) the slope of the relationship between forest structural complexity and BSR was steepest in energy limited locations and negative in energy rich locations. In energy rich locations, forest managers will likely increase landscape-scale diversity by providing all seral-stages and a range of forest structural complexity. In low-energy environments, biodiversity will likely be maximized by managing local high-energy hotspots judiciously and adjusting harvest intensities in other locations to compensate for slower regeneration rates.", "pub_time": "2007"}
{"sha256": "3636f86a3a8e8703f955cccfe33dd11c4b1fb0caf82d93aa843b3ce73a79cdd9", "doi": "", "title": "MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF NEUTROPHILS FROM CALVES WITH BOVINE LEUKOCYTE ADHESION DEFICIENCY: COMPARISON OF NORMAL, HETEROZYGOUS, AND HOMOZYGOUS ANIMALS", "author": "Karen May Lambrecht Sipes", "keyword": "", "abstract": "Bovine leukocyte adhesion deficiency (BLAD) is an autosomal recessive disease of Holstein dairy cattle that is characterized by recurrent bacterial infections. The molecular basis for BLAD involves a mutation in CDl8 resulting in the absence of β2 integrin expression on leukocytes. The β2 integrins play key roles in neutrophil adhesion, chemotaxis, phagocytosis, and receptor signaling. The absence of these adhesion molecules severely impairs leukocyte adherence-dependent functions and results in compromised immunity. Thus, BLAD calves provide a model for investigating the role of β integrins in these neutrophil functions. In the studies described here, surface molecule expression, microbicidal activity, cell maturation, and molecular signaling were studied in neutrophils isolated from heterozygous and homozygous BLAD calves and compared with clinically normal calves. With the exception of the β integrins, surface molecule expression on leukocytes from the three bovine genotypes was similar when evaluated with a panel of monoclonal antibodies. Using three different measurements, neutrophils isolated from homozygous BLAD calves expressed increased NADPH oxidase activity after stimulation when compared to normal and heterozygous BLAD neutrophils. Visual comparison of whole blood smears revealed that homozygous BLAD calves had higher levels of immature neutrophils. Antibody cross-linking of the β subunit (CD18) of the β integrins on normal and heterozygous BLAD neutrophils produced a transient rise in intracellular free calcium, exocytosis of specific granules, shedding of L-selectin, up-regulation of CD18, and redistribution of the protein kinase p58fgr. These responses were absent in homozygous BLAD neutrophils. Immunoprecipitation of homozygous BLAD neutrophil membrane lysates with antibodies against β integrins revealed three protein bands with molecular weights corresponding to two of the three a subunits and the β subunit of the β2 integrins. Western blots confirmed that the CD11b α subunit was not present in these lysates, but the lack of antibodies that cross-react with the bovine β2 integrins hindered the identification of the three bands which may represent defective β2 integrin subunits in animals homozygous for BLAD. Overall, these studies contribute to our understanding of the role of β integrins in neutrophil function.", "pub_time": "1999"}
{"sha256": "d7834fa9127c08c1163c2eaf21f7d47f4e53ab25a17fe9cb2e706421344ee528", "doi": "", "title": "FIELD-SCALE SPATIAL DISTRIBUTION, WATER USE, AND HABITAT OF WILD OAT IN THE SEMIARID NORTHERN GREAT PLAINS", "author": "Lee Russell Van Wychen", "keyword": "", "abstract": "Wild oat (Avena fatua L.) is widely dispersed throughout the Northern Great Plains (NGP), typically occurring in patchy distributions at the field-scale. If weeds are patchy, the environmental impact of weed control and input costs can be reduced through site-specific weed management (SSWM). However, the mechanisms regulating wild oat spatial distribution and the cost effectiveness of SSWM in the NGP need to be understood. Field experiments were conducted to map wild oat distributions and quantify the. accuracy of continuous weed presence/absence maps produced by crop consultants for use in SSWM. The accuracy of wild oat seedling maps was 70%. SSWM of wild oat could be profitable compared to a traditional broadcast herbicide application, even with the associated technology cost and seedling map inaccuracy. Greater increases in SSWM profitability could be realized if scouting and management efforts were directed to field areas with suitable wild oat habitat. I hypothesized that wild oat habitat may be limited by field-scale heterogeneity in plant available water. The effects of water stress on wild oat growth and fecundity was quantified in a greenhouse experiment. Lower soil matric potentials reduced wild oat relative growth rate and unit leaf rate due to an allometric tradeoff of assimilates from leaf tissue in favor of root tissue, but allowed wild oat to reproduce under adverse climatic conditions. Wild oat was estimated to produce seed above soil matric potentials of-1.66 MPa. In three grower-managed cereal grain fields, wild oat was seeded in areas with and without historic wild oat patches to delineate field-scale habitat quality. Almost all wild oat habitat-defining variables (leaf area growth rate, harvest biomass, seeds per plant, biomass water use efficiency, and competitive ratio) were similar between existing patch and non-patch areas. Wild oat grew and produced seed regardless of existing patch boundaries and field-scale heterogeneity in soil water use. Wild oat habitat may be unlimited in agroecosystems of the NGP. Future research efforts should focus on limiting weed fecundity and dispersal instead of correlating soil properties to predict wild oat distribution.", "pub_time": "2002"}
{"sha256": "6c4d19b2c47884790f1ee42668257409df54cf39ec6a4b313d591589994d2465", "doi": "", "title": "Part I - Pinacol rearrangement Part II - chemistry of 4,7,8,9-tetrahydrophthalans Part III - a synthesis of frontalin", "author": "Rodney Dale Otzenberger", "keyword": "", "abstract": " An attempt was made to study the effects of ring size and glycol stereochemistry on the pinacol rearrangement using cis- and trans-perhydrpindan-8, 9-diols. Since only the more stable of the two possible spiroketone products, spiro [4,4 ] nonan-1-one, was obtained, it was concluded that under the conditions used product distribution was determined by product stability, The effect of the oxygen in the tetrahydrophthalans upon the reactivity of the alkene bond was investigated using competitive oxymercuration experiments, A trans-annular stabilization of positive charge by the oxygen non-bonding electrons was proposed to account for the increased reactivity of cis-4, 7,8,9-tetrahydrophthalan, A new synthesis of frontalin, a sex attractant pheromone of the southern pipe beetle, Dendroctonous frontalis, is described utilizing the Diels-Alder reaction of methyl vinyl ketone with methyl methacrylate, lithium aluminum hydride reduction of the adduct to the corresponding alcohol, and cyclization to 1,5-dimethyl-6, 8-dioxabicyclo [3,2,l ] octane, frontalin, by oxymercuration-demercuration.", "pub_time": "1971"}
{"sha256": "6b6c8af83916f3fce78be77116e0066214c88a678180eb7150d827acee054951", "doi": "", "title": "The effects of baclofen on CaM Kinase following cerebral ischemia", "author": "Andrea Joe Mary Everingham", "keyword": "", "abstract": "One enzyme thought to be important in delayed cell death in the CA1 region of the hippocampus following cerebral ischemia is calcium calmodulin kinase II (CaM kinase), which has been shown to disappear in cells that will later die. This study was conducted to confirm the neuroprotective properties of baclofen and evaluate its effectiveness at preserving CaM kinase in the CA1 region of the hippocampus. In Experiment I, Mongolian gerbils were divided into baclofen and saline groups and were anesthetized. Animals were given baclofen (50 mg/kg, i.p.) or saline five minutes before common carotid artery occlusion (five minutes). Animals were also injected with saline or baclofen 24 and 48 hours after ischemia. Three days after surgery sections of the hippocampus were collected and cresyl violet staining was used to assess presence of cells in the CA1 region of the hippocampus. Baclofen significantly protected the cells from damage due to ischemia. Experiment II was conducted to determine the effect of baclofen on CaM kinase 24 hours after ischemia. Four groups of animals were used: baclofen-ischemia, baclofen-sham, saline-ischemia, and saline-sham. The animals were habituated to a T-maze for one week and then trained to perform a delayed non-matched to sample task. Animals underwent occlusion or sham operations with injections of baclofen or saline five minutes before. They were tested in the T-maze task 23 hours after ischemia and were perfused 24 hours after ischemia. Immunohistochemistry for CaM kinase was performed on the brain sections collected. There was no significant difference between the baclofen treated animals and the saline treated animals on the T-maze task, but there was a significant difference between ischemic and sham groups. We also found a significant difference between the baclofen treated animals and saline treated animals in the immunoreactivity of CaM kinase. These studies suggest that baclofen is neuroprotective and also preserves CaM kinase in the CA1 region of the hippocampus. The behavioral test used as a marker of cell death indicates that although it is sensitive to ischemia, there may be factors influencing its effectiveness in testing with baclofen.  ", "pub_time": "1997"}
{"sha256": "002149abdbbe3fb9819b3f3c4e1c23adc538cf78187e0827ca66e844e568abce", "doi": "10.1016/j.fshw.2022.07.064", "title": "Electrospun gelatin/chitosan nanofi bers containing curcumin for multifunctional food packaging", "author": "Mengxia Duan, Jishuai Sun, Yequn Huang, Haixin Jiang, Yaqin Hu, Jie Pang, Chunhua Wu\n", "keyword": "Electrospun nanofibers, Curcumin, NH3 indicator, Active and intelligent packaging, Antibacterial and antioxidant activities", "abstract": "Recently, food grade nanofi ber-based materials have received growing attentions in food packaging. In this work, novel active and intelligent packaging nanofi bers based on gelatin/ chitosan with curcumin (GA/CS/ CUR) were developed via electrospinning technique. Effects of the incorporation of CUR content (0.1% 0.3%, m/m) on the microstructure and functional properties of the electrospun nanofi bers were investigated. Morphological studies using scanning electron microscopy indicated that loading CUR can affect the average diameter of nanofi ber mats, which remained around 160-180 nm. The addition of an appropriate level CUR (0.2%, m/m) led to a stronger intermolecular interaction, and thus enhanced the thermal stability and tensile strength of the obtained nanofi bers. Meanwhile, the incorporation of CUR signifi cantly improved antioxidant activity and the antimicrobial activity of GA/CS/CUR nanofibers. Moreover, the sensitivity of nanofibers to ammonia results indicated that GA/CS nanofibers containing 0.2% CUR (GA/CS/CUR II) presented high sensitivity of colorimetric behavior to ammonia (within 3 min). These results suggest GA/CS/CUR II nanofi bers has great potential as a multifunctional packaging to protect and monitor the freshness of protein rich animal foods, such as meat and seafood.", "pub_time": "2022"}
{"sha256": "6b5d21b6066c040783e3649200cfd4ad6ce92ff5fb5150aa4e4512c89c046b7b", "doi": "10.1016/j.cj.2013.07.009", "title": "HrcQ is necessary for Xanthomonas oryzae pv. oryzae HR-induction in non-host tobacco and pathogenicity in host rice", "author": "Xiaoping Zhang, Chunlian Wang, Chongke Zheng, Jinying Che, Yanqiang Li, Kaijun Zhao", "keyword": "Xanthomonas oryzae pv. oryzae, Tn5-insertion mutant, Type III secretion system, Pathogenicity", "abstract": "Bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most destructive diseases of rice (Oryza sativa L.) worldwide. The type III secretion system (T3SS) of Xoo, encoded by the hrp (hypersensitive response and pathogenicity) genes, plays critical roles in conferring pathogenicity in host rice and triggering a hypersensitive response (HR) in non-host plants. To investigate the major genes conferring the pathogenicity and avirulence of Xoo, we previously constructed a random Tn5-insertion mutant library of Xoo strain PXO99A. We report here the isolation and characterization of a Tn5-insertion mutant PXM69. Tn5-insertion mutants were screened on indica rice JG30, which is highly susceptible to PXO99A, by leaf-cutting inoculation. Four mutants with reduced virulence were obtained after two rounds of screening. Among them, the mutant PXM69 had completely lost virulence to the rice host and ability to elicit HR in non-host tobacco. Southern blotting analysis showed a single copy of a Tn5-insertion in the genome of PXM69. PCR walking and sequencing analysis revealed that the Tn5 transposon was inserted at nucleotide position 70,192–70,201 in the genome of PXO99A, disrupting the type III hrc (hrp-conserved) gene hrcQ, the first gene in the D operon of the hrp cluster inXoo. To confirm the relationship between the Tn5-insertion and the avirulence phenotype of PXM69, we used the marker exchange mutagenesis to create a PXO99A mutant, ΔhrcQ::KAN, in which the hrcQ was disrupted by a kanamycin-encoding gene cassette at the same site as that of the Tn5-insertion. ΔhrcQ::KAN showed the same phenotype as mutant PXM69. Reintroduction of the wild-type hrcQ gene partially complemented the pathogenic function of PXM69. RT-PCR and cellulase secretion assays showed that the Tn5-disruption of hrcQ did not affect transcription of downstream genes in the D operon and function of the type II secretion system. Our results provide new insights into the pathogenic functions of clustered hrp genes in Xoo.", "pub_time": "2013"}
{"sha256": "6b914c1d80f367a0338d1ed36bd910186455645612453c739a2d7b4f84a26c9e", "doi": "10.1016/j.cj.2013.12.001", "title": "Induced defense responses in rice plants against small brown planthopper infestation", "author": "Canxing Duan⁎, Jiaojiao Yu, Jianyu Bai, Zhendong Zhu, Xiaoming Wang", "keyword": "Defense enzyme, Defense gene, Real-time PCR, Rice", "abstract": " Thesmallbrownplanthopper(SBPH),LaodelphaxstriatellusFallén(Homoptera:Delphacidae),is a serious pest of rice (Oryza sativa L.) in China. To understand the mechanisms of rice resistance to SBPH, defense response genes and related defense enzymes were examined in resistant and susceptible rice varieties in response to SBPH infestation. The salicylic acid (SA) synthesis-related genes phenylalanine ammonia-lyase (PAL), NPR1, EDS1 and PAD4 were induced rapidly and to a much higher level in the resistant variety Kasalath than in the susceptible cultivar Wuyujing3inresponsetoSBPHinfestation.TheexpressionlevelofPALin the Kasalath rice at 12 h post-infestation (hpi) increased 7.52-fold compared with the un-infested control, and the expression level in Kasalath was 49.63, 87.18, 57.36 and 75.06 times greater than that in Wuyujing 3 at 24, 36, 48 and 72 hpi, respectively. However, the transcriptional levels of the jasmonic acid (JA) synthesis-related genes LOX and AOS2 in resistant Kasalath were significantly lower than in susceptible Wuyujing 3 at 24, 36, 48 and 72 hpi. The activities of the defense enzymes PAL, peroxidase (POD), and polyphenol oxidase (PPO) increased remarkably in Kasalath in response to SBPH infestation, and were closely correlated with the PAL gene transcript level. Our results indicated that the SA signaling pathway was activated in the resistant Kasalath rice variety in response to SBPH infestation and that the gene PAL playeda considerable role in the resistance to SBPH. ©2013 Crop Science Society of China and Institute of Crop Science, CAAS. Production and hosting by Elsevier B.V. All rights reserved", "pub_time": "2013"}
{"sha256": "00abc2bbb021cde6e262608408f4e3375cbe24986260269f4aca54d49229fc56", "doi": "10.1016/j.cj.2018.05.002", "title": "Red fluorescent protein (DsRed2), an ideal reporter for cotton genetic transformation and molecular breeding", "author": "Lin Sun, Muna Alariqi, Yi Zhu, Jianying Li, Zelin Li, Qing Wang, Yajun Li, Hangping Rui, Xianlong Zhang, Shuangxia Jin", "keyword": "DsRed2；Reporter gene；Transgenic cotton；Molecular breeding；DNA methylation", "abstract": "Genes encoding reporter proteins are used as visual marker-assisted tools in genetic transformation as well as plant breeding. In this study, the red fluorescent protein identified in Discosoma sp. coral (DsRed2) was successfully used as a visual marker for cotton genetic engineering. DsRed2 was successfully expressed in two cotton cultivars, JIN668 and YZ1, driven by the CaMV-35S promoter via the Agrobacterium-mediated transformation. Our results suggest that DsRed2 expression provides an early-stage selection tool for the transgenic calli via visual observation. Red fluorescence can be detected not only in callus and somatic embryos but also in most tissues and organs of mature plants. The transgenic line Yz-2-DsRed2 was crossed with four different cotton cultivars to assess the transgene heritability and stability in different genetic backgrounds. The heritability of the red color was highly stable when Yz-2-DsRed2 was used as a male parent. The DsRed2 gene expressed 100% in the F1 hybrids. To investigate the relationship between DsRed2 transcription and DNA methylation, a methylation-specific PCR approach was applied to the CaMV-35S promoter region. The results showed a negative association between DNA methylation level in the promoter region and the transgene transcription. Taken together, these findings suggest DsRed2 a visual reporter gene for cotton genetic transformation and molecular breeding programs.", "pub_time": "2018"}
{"sha256": "a16b7ffe91b88c569bc1c40374280cbe607eea1b17974f74b2c986b0af9b51c9", "doi": "10.46690/capi.2023.08.01 ", "title": "Molecular insights into structural and dynamic properties of water molecules in calcium silicate hydrate nanopores: The roles of pore size and temperature", "author": "Shaoyan Liu, Hubao A, Shengwen Tang, Ming-feng Kai, Zhibing Yang", "keyword": "Calcium silicate hydrate, water molecule, structural property, dynamic property, pore size, temperature", "abstract": "Calcium silicate hydrate is the primary hydration product of Portland cement and plays a crucial role in determining the strength of cement-based materials. The structural and dynamic properties of water molecules within calcium silicate hydrate nanopores have significant implications for the mechanical and durability performance of these materials. However, the influences of pore size and temperature on the properties of water molecules have not been fully explored. In this work, using molecular dynamics simulations and theoretical analysis, the evolution and mechanisms of the structural and dynamic properties of water molecules in different scenarios with various pore sizes and temperatures are systematically investigated. It is shown that the diffusion coefficients of water molecules increase with both pore size and temperature. Moreover, water molecules have a tendency to adsorb onto calcium silicate hydrate substrates, forming a distinct layered structure. As a result, the water molecules near the surfaces of calcium silicate hydrate substrates exhibit limited mobility, leading to smaller diffusion coefficients compared to those in other regions. Additionally, the distinctions in properties between water molecules and Ca2+ ions are elucidated and the underlying mechanisms behind these differences are also unveiled. The results and findings in this work deepen the understanding of structural and dynamic properties of water molecules within calcium silicate hydrate nanopores, providing valuable insights for improving the mechanical and durability performance of cement-based materials. ", "pub_time": "2023"}
{"sha256": "a175f9e0777d2b7067ca9512e467c78bb14cc8f4ba3c3f96e4b59c79140f13e5", "doi": "10.1007/s12274-017-1876-9", "title": "Silica nanoparticle with a single His-tag for addressable functionalization, reversible assembly, and recycling", "author": "Yuye Cao, Yangdong Cui, Yu Yang, Jie Hua, Zheng-Mei Song, Haifang Wang, Yuanfang Liu, Aoneng Cao", "keyword": "His-tagged nanoparticle, solid phase, reversible assembly, addressable functionalization, protein orientation", "abstract": "For many biomedical and catalytic applications, such as encapsulation of proteins/enzymes in nanoparticles (NPs), it is preferable to have well-dispersed small NPs that are stable in solution and behave quasi-homogeneously. However, conventional liquid phase methods for small-NP synthesis and functionalization usually face great difficulties in separation/purification and recycling. In addition, controlling the orientation of proteins inside NPs is also a crucial issue to maximize the activity of the encapsulated proteins. Herein, we report a solid phase method to solve these problems. Using His-tagged proteins as cores, well-dispersed core-shell silica NPs are facilely synthesized and functionalized in a column. The core His-tagged proteins are kept bound on the surface of the resin beads in the column during the entire process, making the separation/purification of NPs and their precursors during the multiple-step process as simple as a few-minutes procedure of draining and washing the column. Each obtained silica NP has an adjustable eccentric core-shell structure with only one His-tag sticking out of the particle. This single His-tag on the surface of each NP not only makes it easy for addressable and stoichiometric functionalization of the NP but also provides an easy way to reversibly assemble NPs into dimers or be oriented on the surface of large particles. Notably, this solid phase approach also provides a versatile means to control the orientation of proteins inside NPs, and the His-tag makes it easy to recycle those well-dispersed small NPs. ", "pub_time": "2018"}
{"sha256": "6bfb281b9f6ae486b9540cc392c19dbf3ad4bcb19cfc665d42061c59634f15fb", "doi": "10.1007/s12274-021-3764-6", "title": "Natural polymers based triboelectric nanogenerator for harvesting biomechanical energy and monitoring human motion", "author": "Hong Chen, Qixin Lu, Xia Cao, Ning Wang, Zhong Lin Wang", "keyword": "triboelectric nanogenerator, natural polymers, biomechanical energies, human motion monitoring", "abstract": " Triboelectric nanogenerator (TENG) has been proved as a promising energy harvester in recent years, but the challenges of exploring economically triboelectric materials still exist and have aroused interests of many researchers. In this paper, chitosan silk fibroin-airlaid paper composite film (CSA film) was fabricated and then the CSA film based-triboelectric nanogenerator (CSA TENG) was constructed, which presents an opportunity for natural polymers to be applied in triboelectric materials. Due to the excellent electron donating ability of CSA film, the CSA-TENG can harvest environmental energy with a high efficiency. More importantly, the as-designed CSA film based dual-electrode triboelectric nanogenerator (CSA-D-TENG) is successfully assembled into hand clapper and trampoline to harvest mechanical energies generated by human bodies, it is also capable of monitoring human movement while harvesting biomechanical energies. This work provides a simple and environmental-friendly way to develop TENG for biomechanical energies harvesting and human motion monitoring", "pub_time": "2021"}
{"sha256": "d83e265951f4548f9687005ceb7b020b865d91c6002a4507fa784b61cdab8b92", "doi": "10.1007/s12274-023-5703-1", "title": "Enhanced electroreduction of CO₂ to C₂+ fuels by the synergetic effect of polyaniline/CuO nanosheets hybrids", "author": "Lian Ma, Qinghong Geng, Longlong Fan, Jun-Xuan Li, Dawei Du, Junli Bai, Cuiling Li\n", "keyword": "electrochemical CO₂ reduction, CuO nanosheets (NSs), electrocatalysis, polyaniline (PANI), C₂+ selectivity", "abstract": "Electrochemically converting CO₂ to value-added multi-carbon (C₂+) fuels and chemicals is a favorable way to achieve carbon neutrality. Here, polyaniline/CuO nanosheets (PANI/CuO NSs) hybrid electrocatalysts are developed in order to achieve superior C₂+ selectivity by imparting PANI functional component to the CuO NSs. The decorated PANI nanoparticles (NPs) can effectively stabilize the •CO intermediates and increase their coverage on the active Cu sites, which facilitates the C–C coupling to form multi-carbon products. Benefiting from the synergic effect of PANI and CuO NSs, best Faradaic efficiency (FE) for C₂+ product up to 66.4% at −1.6 V vs. reversible hydrogen electrode (RHE) in a H-cell measurement and 60.0% at 400 mA·cm⁻² in a flow cell measurement are demonstrated by PANI/CuO NSs-25 sample. More importantly, the C₂+ selectivity keeps stable even in a continuous measurement time period of 92 h in H-cell. The present study may provide more insights for designing efficient hybrid materials toward superior C₂+ production from electrocatalytic CO₂ reduction.", "pub_time": "2023"}
{"sha256": "6b4b36ded7010a7a4c33bb7f07385f78f2fdf8880ebc3af74f114735a90c17aa", "doi": "10.12677/jc.2024.121023", "title": "温州市公众科普需求调研分析及对策研究", "author": "张小华, 徐欢欢, 刘光道, 范成武", "keyword": "科技创新, 科普需求, 科普教育", "abstract": "伴随着科技日益的发展进步，公众的科普需求也日渐提高，如何提高科普工作的有效性和针对性成为需要关注的问题。因此，有必要梳理公众的科普需求特征，为基于公众视角提高科普工作提供参考。本研究采用问卷调研法、比较分析法等方法对温州市的科普需求进行调查和分析，并对当前科普工作存在的问题提出相关对策建议，提高科普工作的效果。", "pub_time": "2024"}
{"sha256": "d82dd722e447298c6b7bccc305d7fd300bb449ca5b9303c7353c5e44ddefcd85", "doi": "10.12677/ap.2017.73052", "title": "双薪夫妇成人依恋对婚姻质量的影响：家庭结构和家庭周期的调节作用", "author": "吴梦玲", "keyword": "双薪夫妇, 家庭结构, 家庭周期, 成人依恋, 婚姻质量\n", "abstract": "本研究以98对(196人)双薪夫妇为样本考察了中国双薪夫妇婚姻质量的特点，并采用分组结构方程模型 分别检验了家庭结构和家庭周期对成人依恋和婚姻质量关系的调节效应。结果发现：(1) 依恋回避和依 恋焦虑都对婚姻质量存在显著的负向影响；(2) 婚姻质量在家庭结构和家庭周期上存在显著差异；(3) 家 庭结构和家庭周期分别对成人依恋和婚姻质量的关系起调节作用。这些结果说明，成人依恋是影响婚姻 质量的重要因素，家庭结构和家庭周期在其中起着重要的调节作用。", "pub_time": "2017"}
{"sha256": "35b7a482ec4a1c09126c03ff9a020cf02685e828e30360957fa88beaa7dbad2c", "doi": "10.12677/acm.2024.141014", "title": "肿瘤放化疗患者营养管理模式研究进展", "author": "孙丽丽, 明洁, 代晓雪, 王海娟, 徐笑, 魏玉玲", "keyword": "肿瘤放化疗, 营养管理, 营养筛查, 营养评估, 营养护理", "abstract": "肿瘤放化疗患者的营养管理对其治疗、康复至关重要，目前肿瘤放化疗患者营养管理模式仍是处于探索 实践阶段，尚无统一标准。笔者从营养管理团队、营养筛查、评价指标、营养管理内容及模式等方面总 结分析近年来肿瘤患者营养管理模式与护理进展，为营养管理的开展提供决策支持和科学依据。 ", "pub_time": "2024"}
{"sha256": "002be7cdfc191fd01d1b6bb9552909907d7508f5c51b0f5919f1fe83e28b6c74", "doi": "10.12677/md.2022.122023", "title": "2018~2020年大理市某三甲医院嗜血杆菌感染分布及耐药性分析", "author": "周宇, 刘永磊, 樊玉娟, 徐世豪, 杨林", "keyword": "嗜血杆菌, 呼吸道感染, 耐药性", "abstract": "目的：分析大理大学第一附属医院流感嗜血杆菌感染分布特点、耐药性及其变化趋势。方法：对大理大学 第一附属医院2018年1月初至2020年12月底患者的口痰、咽拭子标本进行分离培养和细菌鉴定、药敏试 验和结果判定，对数据进行统计分析。结果：共分离205株流感嗜血杆菌，流感嗜血杆菌195株，副流感 嗜血杆菌15株。标本主要来源于痰液(93.16%)、咽拭子(5.79%)；男性(69.47%)比女性(30.53%)患病率 更高。流感嗜血杆菌与副流感嗜血杆菌均对氨苄西林的耐药率高于63.74%，对复方磺胺甲噁唑的耐药率 高于53.33%，对头孢呋辛耐药率高于26.37%，而对氨曲南、氯霉素、美罗培南、头孢他啶、阿奇霉素的 耐药率低(0.00%~33.33%)，尤以美罗培南耐药率最低(0.00%~2.20%)。结论：嗜血杆菌感染好发于低龄 儿童、免疫力低下以及患有慢性呼吸系统疾病的人群，嗜血杆菌对药物复方磺胺甲噁唑和氨苄西林耐药性 高，但对美罗培南耐药性较低，临床医生应根据药敏结果合理选用抗生素，避免耐药菌株的产生。 ", "pub_time": "2022"}
{"sha256": "d845c30c98a48c3921cadd9a8a8e7f8d27b23156b74c92bd1154ff1293e90c4b", "doi": "10.12677/AMB.2021.104023", "title": "嗜盐菌对高盐废水处理的研究进展", "author": "魏莉荣, 王纪晗, 徐毓东, 耿合定, 赵辉, 闫华晓, 韩作振", "keyword": "嗜盐菌, 高盐废水, 废水处理, 经济节约, 环境友好", "abstract": "许多工业生产活动都会产生废水，有些废水含高盐度、高有机质和其他可危害环境的污染物。目前， 含盐废水的处理已成为许多国家关注的重要问题之一。本文介绍了高盐废水的来源、特点，以及传统 处理高盐废水的方法和存在的缺陷。嗜盐菌因为其生长环境特殊，利用其具有的独特功能来处理高盐 废水，是一种经济节约、环境友好的好方法。嗜盐菌在高盐废水处理中有巨大应用潜力。本文阐述了 嗜盐菌的分类及嗜盐机理，同时对去除高盐废水中的石油烃类、重金属以及氮磷等的研究进展进行了 综述，最后，展望了嗜盐菌在处理废水中的应用前景和面临的挑战，为后续的嗜盐菌处理高盐废水等 研究提供参考。", "pub_time": "2021"}
{"sha256": "35c289b3a22bdec38c09b4cb3155c9be49c4488de2e346425141bf7be7112cb4", "doi": "10.12677/gser.2024.131018", "title": "基于信息流视角的甘肃省城市网络结构特征研究", "author": "许联鑫", "keyword": "城市网络, 百度指数, 甘肃省", "abstract": "从不同视角剖析中国城市网络的结构特征对于深刻认识中国城市网络结构及模式具有重要意义。信息流得益于互联网的发展突破了传统时空距离的约束，是表征区域联系的重要指标。基于百度指数对甘肃省城市网络结构特征进行研究，结果发现：1) 基于信息流视角的甘肃省城市网络结构表现出明显的核心-边缘特征，兰州是省内唯一的核心，且核心地位仍在进一步加强，省内缺乏明显的信息流强度第二位的城市。2) 甘肃省城市信息流的离散程度较高，各城市信息流分布比较分散。3) 甘肃省河西地区城市间信息联系普遍下降，黄河以东以南的地区城市对信息联系普遍增强；除省会兰州之外的其他城市间信息联系整体较弱，且这种弱势程度还在进一步加深。本研究可以为甘肃城市与区域协同发展以及更好发挥甘肃区位优势提供一些思路和参考。", "pub_time": "2024"}
{"sha256": "35caa18f4766291750eed16e8d9b039c2bd0952e1f55fb91d95b81d9180047d7", "doi": "10.12677/ap.2020.102023", "title": "面孔熟悉度对4~5岁幼儿注视追随的影响", "author": "刘来", "keyword": "注视追随, 熟悉度, 4~5岁幼儿, 注视线索范式", "abstract": "注视追随是指个体追随他人眼睛注视方向转移注意的现象，本研究使用标准注视线索范式来检验面孔熟悉度对幼儿注视追随的影响。结果显示，当SOA为200 ms时，幼儿追随了高熟悉度面孔的注视，但没有追随低熟悉度面孔的注视；SOA为800 ms时，幼儿既没有追随高熟悉度面孔的注视，也没有追随低熟悉度面孔的注视。说明熟悉度调节注视追随的自动化加工成分，对幼儿注视追随的影响是快速且自动的。未来研究需进一步明确影响注视追随是自动化加工或控制加工的情境因素。 ", "pub_time": "2020"}
{"sha256": "35ceadbed98daa289ba4dfd004b296530c00762cda84b1676e8176a3986de202", "doi": "10.12677/aepe.2023.111001", "title": "基于IBAS-BP神经网络的风功率预测", "author": "掌旭, 刘文超, 徐世龙, 邹邦柱, 吴昊, 修唯, 张煜", "keyword": "风电功率预测, BP神经网络, 改进天牛须算法, 鲸鱼算法", "abstract": "风电功率预测精度对风电场调度有着重要意义。针对目前预测方法中模型预测精度不高且训练速度较慢 等问题，提出一种改进天牛须算法优化神经网络参数的短期风电功率预测模型。采用群体寻优的方式改 进BAS算法，并在信息选取利用时提出精英个体概念，对现有精英个体继续进行寻优，从而改善了原始 模型在权重更新的过程中易出现局部极值的问题。", "pub_time": "2023"}
{"sha256": "0012426d62e7ecda687d975d3668ac466b078b46e86e140fd8d9b97e24e7cbd7", "doi": "10.12677/ae.2023.135483", "title": "汉语方言背景下海外华裔学生习得汉语语法偏误研究的现状与思考", "author": "李芯梦", "keyword": "汉语方言, 海外华裔, 习得, 语法偏误", "abstract": "汉语作为第二语言教学在海外发展日渐蓬勃，但在国际中文教学中，如何处理好普通话与方言之间的关 系，也是二语教学中需要注意的问题。普通话和方言，在语音、词汇、语法等方面存在差异，这些差异 容易导致有汉语方言背景的华裔汉语学习者受到母语方言的影响。通过对中国知网、维普和万方2009 年至2021年间关于海外华裔学生习得汉语语法偏误研究文献的整理，发现以海外华裔学生为研究对象的 汉语语法习得研究数量不多，仅17篇。其中，以有汉语方言背景的华裔学生为研究对象的相关研究数量 仅见2篇。以上研究主要以华裔习得语法句式偏误分析研究为主，在分析研究现状的基础上，结合国际 中文教育的现实需要，对该领域提出了研究展望和未来的研究方向。", "pub_time": "2023"}
{"sha256": "6b92b9a867cc3af789e170889be9dc82136d012062b4ba8e026c925a0885516e", "doi": "10.12677/jee.2017.54038", "title": "光伏水泵群控系统的最大功率跟踪及稳定控制", "author": "陈彦丰, 苏建徽, 刘鹏", "keyword": "光伏水泵, 非均衡功率搜索, 最大功率点跟踪, 水泵饱和", "abstract": "本文将非均衡功率扰动搜索应用于光伏水泵系统中，通过非均衡功率扰动搜索阵列的最大功率，研究了如何在保持已运行水泵频率不变的前提下，更加准确的获取阵列最大功率。同时在水泵系统的运行时，防止系统的阵列功率有大幅度跌落，在比例控制的基础上，加入了频率闭环，即使阵列功率出现大幅跌落，系统仍可保持稳定。", "pub_time": "2017"}
{"sha256": "d7ceccdbeb88c925d22cacb9bfae7d53ce640c0840103187c514e683abf66fc0", "doi": "10.3390/children10040606", "title": "Visual Autism", "author": "Margaret Reynolds, Susan M. Culican", "keyword": " blindism; visual autism; congenital blindness; autism spectrum disorder", "abstract": " Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors. It affects approximately 2.2% of children. Both genetic and environmental risk factors have been identified for ASD. Visual comorbidities are relatively common among children with ASD. Between 20 and 44% of ASD children have visually significant refractive error, on-third have strabismus, and one-fifth have amblyopia. In addition, ASD is 30 times more common in children with congenital blindness. It is unknown whether the association of ASD with visual morbidity is causal, comorbid, or contributing. Structural and functional abnormalities have been identified in MRIs of ASD children, and ASD children have been noted to have aberrant eye tracking. ASD children with visually significant refractive errors and poor spectacle compliance (present in 30% of ASD children) offer the opportunity for investigation into how improved visual acuity influences ASD behaviors. In this review, we focus on what is known of the visual system, refractive surgery, and ASD", "pub_time": "2023"}
{"sha256": "d7ddb587645bb924355a0e92f6a5c2ca4a3929e820d8aeb005d760482567ad04", "doi": "10.3390/antibiotics10121447", "title": "In Silico Analysis of PKS and NRPS Gene Clusters in Arisostatin- and Kosinostatin-Producers and Description of Micromonospora okii sp. nov.", "author": "Hisayuki Komaki, Natsuko Ichikawa, Akira Hosoyama, Moriyuki Hamada and Yasuhiro Igarashi\n", "keyword": "arisostatin; classification; kosinostatin; Micromonospora; polyketide; quinolidomicin; secondary metabolite", "abstract": "Micromonospora sp. TP-A0316 and Micromonospora sp. TP-A0468 are producers of arisostatin and kosinostatin, respectively. Micromonospora sp. TP-A0316 showed a 16S rRNA gene sequence similarity of 100% to Micromonospora oryzae CP2R9-1ᵀ whereas Micromonospora sp. TP-A0468 showed a 99.3% similarity to Micromonospora haikouensis 232617ᵀ. A phylogenetic analysis based on gyrB sequences suggested that Micromonospora oryzae TP-A0316 is closely related to Micromonospora oryzae whereas Micromonospora sp. TP-A0468 is an independent genomospecies. As Micromonospora sp. TP-A0468 showed some phenotypic differences to its closely related species, it was classified as a novel species, for which the name Micromonospora okii n. nov. is proposed. The type strain is TP-A0468ᵀ (= NBRC 110461ᵀ). Micromonospora sp. TP-A0316 and M. okii TP-A0468ᵀ were both found to harbor 15 gene clusters for secondary metabolites such as polyketides and nonribosomal peptides in their genomes. Arisostatin-biosynthetic gene cluster (BGC) of Micromonospora sp. TP-A0316 closely resembled tetrocacin A-BGC of Micromonospora chalcea NRRL 11289. A large type-I polyketide synthase gene cluster was present in each genome of Micromonospora sp. TP-A0316 and M. okii TP-A0468ᵀ. It was an ortholog of quinolimidomicin-BGC of M. chalcea AK-N57 and widely distributed in the genus Micromonospora.\n", "pub_time": "2021"}
{"sha256": "d7e2ca777bfd8681dee30ba009e721287b8697af0fd750c57c3b02f11f2c6cf7", "doi": "10.3390/ijms241612819", "title": "Bridging the Gap between Gut Microbiota and Alzheimer’s Disease: A Metaproteomic Approach for Biomarker Discovery in Transgenic Mice", "author": "Esra Ayan, Hasan DeMirci, Muhittin Abdulkadir Serdar, Francesca Palermo and Ahmet Tarık Baykal", "keyword": "neurodegeneration; Alzheimer’s Disease; proteomics; metaproteomics; gut microbiota; 5xFAD mice", "abstract": "Alzheimer’s Disease (AD) is a progressively debilitating form of dementia that affects millions of individuals worldwide. Although a vast amount of research has investigated the complex interplay between gut microbiota and neurodegeneration, the metaproteomic effects of microbiota on AD pathogenesis remain largely uncharted territory. This study aims to reveal the role of gut microbiota in AD pathogenesis, particularly regarding changes in the proteome and molecular pathways that are intricately linked to disease progression. We operated state-of-the-art Nano-Liquid Chromatography Mass Spectrometry (nLC-MS/MS) to compare the metaproteomic shifts of 3-month-old transgenic (3M-ALZ) and control (3M-ALM, Alzheimer’s Littermate) mice, depicting the early onset of AD with those of 12-month-old ALZ and ALM mice displaying the late stage of AD. Combined with computational analysis, the outcomes of the gut–brain axis-focused inquiry furnish priceless knowledge regarding the intersection of gut microbiota and AD. Accordingly, our data indicate that the microbiota, proteome, and molecular changes in the intestine arise long before the manifestation of disease symptoms. Moreover, disparities exist between the normal-aged flora and the gut microbiota of late-stage AD mice, underscoring that the identified vital phyla, proteins, and pathways hold immense potential as markers for the early and late stages of AD. Our research endeavors to offer a comprehensive inquiry into the intricate interplay between gut microbiota and Alzheimer’s Disease utilizing metaproteomic approaches, which have not been widely adopted in this domain. This highlights the exigency for further scientific exploration to elucidate the underlying mechanisms that govern this complex and multifaceted linkage.", "pub_time": "2023"}
{"sha256": "d7e48b9de8200cecefcef401ccf28c8de03dc98f5c670b7294dee6d56e9001c6", "doi": "10.3390/IECPS2020-08604", "title": "Plants Biodiversity in Olive Orchards and Surrounding Landscapes from a Conservation Biological Control Approach", "author": "María Villa, Sónia A. P. Santos, Carlos Aguiar and José Alberto Pereira\n", "keyword": "food sources; pollen; nectar; natural enemies; pest control; Mediterranean areas", "abstract": "Many natural control agents of olive pests need pollen and nectar from non-crop plants in order to complete their life cycles. However, a deep knowledge about the occurring plant species in the agroecosystem is necessary to select the plant species to be maintained or enhanced from a conservation biological control approach. Thus, in this study, the goal was to increase the understanding about the plants’ biodiversity in an important olive-producing region in the northeast of Portugal. For that, on a weekly basis during the spring and every other week in the summer and autumn, blooming plant inventories were accomplished in three olive orchards with spontaneous vegetation and its surroundings (woody and herbaceous vegetation areas) from April to December of 2012 and 2013. The percentage ground cover for each flowering plant species was recorded following the Daubenmire cover scale modified by Bailey. A total of 258 plant species belonging to 47 families were identified. The most abundant family was Asteraceae, followed by Poaceae, Fabaceae and Brassicaceae. Several species were specific to each land use and presented different flowering periods, representing a potential variety of food sources across the seasons. Additionally, some of the identified species are known for their implications as providers of the key requisites for natural control agents. These results provided us with valuable information for the implementation of conservation biological control measures. ", "pub_time": "2020"}
{"sha256": "d7e6c45cf2c985ac4ea3a176796b3340256e43687a5d1075f2ca5709c43eb223", "doi": "10.3390/land13060781", "title": "Long-Term Response of Floodplain Meadow Normalized Difference Vegetation Index to Hydro-Climate and Grazing Pressure: Tamir River Plains, Mongolia", "author": "Lkhaakhuu Nyamjav, Soninkhishig Nergui, Byambakhuu Gantumur, Munkhtsetseg Zorigt and Roland Jansson", "keyword": "NDVI; climate change; hydro-climatic factors; grazing intensity; dzud events; floodplains; Mongolia", "abstract": "The greenery of floodplain meadows in arid regions, such as Mongolia, is influenced by climate, hydrology, and land use. In this study, we analyzed the NDVI (Normalized Difference Vegetation Index) of two floodplain meadows located along the South Tamir and Tamir Rivers using LANDSAT images. Our goal was to observe NDVI spatial changes, variations, and mean values in mid-August every six years from 1991 to 2015 and to identify the factors driving these differences. To achieve this, we conducted variance analysis to identify changes in NDVI and implemented Principal Component Analysis to determine the influence of hydro-meteorological factors and grazing intensity. Our findings indicate a significant decrease in greenness, as measured by pixel-scale NDVI, during the late summer period. This decrease was consistently observed, except for a series of harsh winters that followed relatively dry summers, resulting in a disastrous event called dzud, which led to the death of livestock. The decrease in NDVI was amplified by lower precipitation in June, higher temperatures and wind speed in July, and increased precipitation in August, along with a higher frequency of days with convective rain. Our findings have important implications for managing grazing in Mongolia’s grasslands, promoting sustainable land use, and mitigating sandstorms. The variance and average values of NDVI at the pixel level can serve as reliable markers of sustainable pasture management in areas where other vegetation measures are limited.", "pub_time": "2024"}
{"sha256": "35ae796913eca3c71d3c0a84dcbd08c20ba06ca55f43340ab0f6deb8469aec89", "doi": "10.3390/systems11050233 ", "title": "Path Optimization of Technological Innovation Efficiency Improvement in China’s High-Tech Industries Based on QCA and GA-PSO-BP Neural Network", "author": "Yuanyuan Kou, Huiying Chen, Kai Liu, Yanping Zhou, Huajie Xu", "keyword": "technological innovation efficiency; path optimization; China’s high-tech industries; qualitative comparative analysis; GA-PSO-BP neural network", "abstract": "Innovation is the main driving force to promote national technological progress. It is of great significance to explore the optimal path to improve innovation efficiency by using the qualitative method and neural network prediction model to promote the high-quality development of the national economy. This study focuses on high-tech industries in the eastern, central and western regions of China; a factor-dependent research framework for innovation efficiency improvement in high-tech industries is constructed in China. The fuzzy-set qualitative comparative analysis method (QCA) is used to explore multiple paths to enhance the innovation efficiency of China’s high-tech industries. Then, a GA-PSO-BP neural network is used to construct an optimization model for the enhancement path of technological innovation efficiency, which clarifies the optimal path for the enhancement of innovation efficiency of high-tech industries in the eastern, central and western regions of China. Finally, innovation management strategies for high-tech industries are presented with regional features. The study finds that none of the individual conditions are necessary to promote the innovation efficiency of China’s high-tech industries, and only the linkage effect of the factors can achieve the goal of improving the innovation efficiency level of China’s high-tech industries. There are four configuration paths to improve the innovation efficiency of China’s high-tech industries, which are: “Multinational company (MNC) innovation—economic development—government support”; “MNC innovation—government support”; “economic development—government support”; and “economic development”. The characteristics of regional heterogeneity make differences in the optimal paths of innovation efficiency improvement in high-tech industries in eastern, central and western regions of China.", "pub_time": "2023"}
{"sha256": "d6fd3156b2e927cf82c118abaaa1e93e9304d7c1521e6fa00448138b54e769c2", "doi": "", "title": "THE IMPACT OF TERRORIST ATTACKS UPON THE GLOBAL ECONOMY", "author": "Codrin Horaţiu Miron, Lucian Cernuşca", "keyword": "terrorism, global economy, Business Continuity Plan", "abstract": "", "pub_time": "2008"}
{"sha256": "d700226157e01d5e9aaf48735b54dd8411ce867fadf37f5737a6ec6202ca3333", "doi": "", "title": "基于线性自抗扰的开关磁阻电机控制器设计", "author": "吴江", "keyword": "开关磁阻电机, 双闭环控制, PI控制, 线性自抗扰控", "abstract": "开关磁阻电机（Switched Reluctance Motor，SRM），机械结构简单、稳定性好，应用范围广，工作状态时的绕组相互独立，具有调速范围宽、效率高、动态响应好等优异性能，在航空工业、新能源电动汽车、油田抽油机、家电等领域得到广泛的应用。但是，由于电机运行时磁路的非线性和转矩脉动严重，并且难以精确建立开关磁阻电机的动态模型，导致对开关磁阻电机转速的控制较为复杂，因此高性能的转速控制研究尤为重要。针对上述问题，本文提出了一种基于线性自抗扰控制（LADRC）的SRM转速双闭环控制策略，主要的工作内容有：\n针对传统的PI双闭环控制SRM转速的问题，设计了基于LADRC的SRM转速控制器，为了验证LADRC转速控制策略的可行性和高效性，分别设计了转速外环PI控制和电流内环PI控制、转速外环LADRC控制和电流内环PI控制、转速外环PI控制和电流内环LADRC控制、转速外环LADRC控制和电流内环LADRC控制四种双闭环调速控制器，并且对四种控制方式在设定转速、转速突变和负载突变情况下进行仿真，验证了LADRC双闭环控制的可行性，能够较好的解决SRM调速的快速性与超调的矛盾。\n针对LADRC双闭环控制SRM转速的实验验证问题，设计了基于LADRC的SRM调速控制的软硬件系统，搭建了额定功率1.5KW的三相12/8极开关磁阻电机实验平台，然后对双闭环的LADRC控制方式和双闭环的PI控制方式控制效果进行实验验证，实验结果表明，基于LADRC控制的转速双闭环控制策略在快速、超调和抗扰动方面均优于PI控制。\n本文所提出的基于LADRC的转速双闭环控制策略，实现了对SRM的高性能转速控制，设计的基于LADRC的SRM控制器，具有一定工程应用价值。", "pub_time": "2019"}
{"sha256": "d702bb30d414f360a9b6dc983d6d7790ba715ac4d84bff3413588a7f8348c138", "doi": "10.1515/eoik-2015-0010", "title": "PREDUZETNIČKO OKRUŽENJE I KONKURENTNOST U BIH I SRBIJI", "author": "Jelena Mićić, Marko Šarčević", "keyword": "preduzetništvo, konkurentnost, produktivnost, preduzetničko okruženje, indikatori konkurentnosti", "abstract": " Bosnia and Herzegovina together with Serbia shows the poor economic performance com pared to neighbor countries, while the European average remains a remote and largely unattaina ble category. The reasons for this unsatisfactory situation are many, and this paper aims to high light the entrepreneurial aspect of the econom ic dynamics of these countries compared to the world, European and regional average. We will use comparative, statistical, dynamical and cog nitive analysis and synthesis in order to get better insight into the causes of our current situation, as well as recognizing the potential comparative advantages. Through presentation of the BiH and Serbia position in the Reports of the World Economic Forum in relation to the weighted av erages of the world, Europe and the region, and further through the analysis of the basic param eters of competitiveness and detailed analysis of business environment indicators we will reach important conclusions about the most important shortcomings and potential advantages of en trepreneurship in BiH and Serbia. These results should be kept in mind while creating future eco nomic measures, and they have considerable us able value for current and future entrepreneurs.", "pub_time": "2015"}
{"sha256": "d703683911dc67e9465ae77b98fef6b817518979370b6c61ede68da1587fd2ed", "doi": "", "title": "Unfamiliar Journey: Baudelaire in the Work of Jean-Luc Godard", "author": "Ioan Pop-Curșeu", "keyword": "Baudelaire, Godard, Poe, cinema, poetry, film theory. ", "abstract": "This paper examines the importance of Baudelaire and his work in the cinematographic activity of Jean Luc Godard. In the introduction, the focus is placed on the context, because the film directors of the Nouvelle Vague were very interested in reading and interpreting Baudelaire through their creations. Godard participates to this cultural trend, but he engages more than any other director in a dialogue with Baudelaire. This dialogue occurs on three levels, each one being analysed in a distinct part of the paper. Firstly, the allusions and references to Baudelaire’s work in Godard’s films are gathered and interpreted. Secondly, Baudelaire is seen through Godard’s interest in Poe’s stories and narratives. Thirdly, we emphasise and discuss the importance of Baudelaire, the art critic, for Godard, as a film theorist.", "pub_time": "2018"}
{"sha256": "d703a4989b069efb3c879a44585ffef09ffbcb77dffa78cc66fd12739fa0d5a3", "doi": "", "title": "Global Large Debt Reduction: Lessons for the Caribbean", "author": "CHARLES AMO-YARTEY, JOEL CHIEDU OKWUOKEI", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "d703e76382b2d4325b544a08272b611959b184bf888d32cc45b3a7dea0ef95e0", "doi": "", "title": "中国核心通货膨胀率的测算研究", "author": "汪静文", "keyword": "通货膨胀, 核心通货膨胀, SVAR模型, 截尾平均法", "abstract": "通货膨胀是一种常见的经济现象，但是在经济学理论中，通货膨胀将会影响财富分配和产出、就业，所以有效的观测和度量通货膨胀尤为重要。\n度量通货膨胀的常用指标有：居民价格指数、生产者价格指数、GDP平减指数和批发物价指数等。我国通常将CPI作为重要的度量指标，但是宏观经济形势的变动往往是多种复杂的冲击相互作用造成的结果，这也使得CPI无法准确表达国内的真实状况，成为制定货币政策的有效依据。西方经济学家认为应该根据核心通货膨胀来制定经济政策。通货膨胀应该关注的是其中能够被货币政策影响的中长期的趋势性部分。目前很多国家都用核心通货膨胀指数来评估经济状况如美国，英国，加拿大。然而，国家统计局还未正式公布核心通货膨胀指标相关信息，而且是全球主要经济体中唯一不公布核心通货膨胀率的，这对我国要在未来要应对诡谲多变的经济环境不得不说是一个缺憾。\n核心通货膨胀不是一个新的概念，是对通货膨胀的一种度量方法，是较原有的度量指标，如CPI、PPI等更优的度量指标。但是，核心通货膨胀不是对原有的度量指标的替代，而是补充。关于核心通货膨胀的度量方法包括剔除法、截尾平均法、SVAR模型法和加权中位数法等。\n本文旨在系统的引入核心通货膨胀理论，对通货膨胀理论和现有度量指标、核心通货膨胀定义、作用、优势、度量方法等方面做了详细的介绍和比较分析。基于Wynne（1999）、Vega和Wynne（2003）提出的核心通货膨胀率度量方法的期望性质及评价，结合中国国情，本文认为采用截尾平均法和结构向量自回归（SVAR）方法更为合理可靠。最后在核心通货膨胀的应用和方法的选择以及国家统计部门在发布通货膨胀指数的时效性和准确性上提出了建议和意见。\n在目前的学术研究中采用的样本的时间不是最新的，对于现在的核心通货膨胀的研究的参考价值将会下降。一般文章都只采用一种测度方法来研究估计核心通货膨胀，但是任何一种测度方法都有其缺陷。\n本文在借鉴以前学术观点的基础上进行修改，首先定义了核心通货膨胀是什么，其次构建了计量模型进行估算。本文选用SVAR模型和30％单侧截尾平均模型相结合来估算核心通货膨胀率。本文的创新之处：（1）先分别用SVAR和截尾平均法模型测算出估计值，再用加权得到最终的估计值。（2）新性的将两种模型结合，融合了两种方法的优点并做到优势互补。", "pub_time": "2018"}
{"sha256": "d704dd6505ce2aae08a5d1592a19d6c64f72e00f0f1c6076e3d117eb19c9d08a", "doi": "", "title": "霍山石斛（栽培）抗炎多糖的结构鉴定及活性评", "author": "王淑琪", "keyword": "霍山石斛, 多糖, 抗炎活性, 结构特征, 巨噬细胞", "abstract": "霍山石斛（Dendrobium huoshanense）是我国一种传统的药用植物，其茎部位可经加工成为枫斗，是一种珍贵的补品。本文以栽培的霍山石斛茎部位为原料提取多糖，以小鼠 Raw264.7 巨噬细胞为模型评价多糖的抗炎活性，并对高活性组分的结构进行解析，对其抗炎信号转导机制进行探讨，以期为阐明霍山石斛多糖功能与结构之间的联系奠定基础。\n（1）以巨噬细胞释放炎性介质 NO 水平为指标，对霍山石斛不同成分进行活性导向分离，经脱脂、水提醇沉、DE-52 阴离子交换树脂分离、乙醇分级，获得 抗炎活性不同的 5 种组分，其中以多糖组分 cDHP-W1 抗炎活性最佳。\n（2）理化性质分析表明，cDHP-W1 是一相对分子质量为 24 kDa、主要由 Man 和 Glc 按 1.00 : 8.21 摩尔比所组成的均一多糖，其碳水化合物含量为 97.79%， 特性粘度（ŋ）为 0.7192，并含有 4.3%乙酰基和 1.4%的糖醛酸。高碘酸氧化、FT-IR、GC-MS 及 1D 和 2D NMR 分析揭示，cDHP-W1 的主链由 1,4-linked-Glcp、 1,4-linked-Manp 和 1,4,6-linked-Glcp 所组成，其支链为 T-linked-Glcp。\n（3）利用 LPS 诱导的巨噬细胞炎症模型，初步探讨了 cDHP-W1 的抗炎活性及其作用机制。浓度梯度实验表明，cDHP-W1 能够剂量依赖地抑制 LPS 诱导的 NO、PGE2、TNF-α 和 IL-1β 等炎性介质的分泌，当浓度达到 200 μg/mL 时，抑制效果最为显著。LPS 及 cDHP-W1 处理时间实验表明，当 cDHP-W1 预处理时间为 1 h、LPS 处理时间为 24 h 时，cDHP-W1 对 NO、PGE2、TNF-α 和 IL-1β 分泌的 抑制效果最佳。\nRT-PCR 分析表明，不同的 LPS 及 cDHP-W1 处理时间下，iNOS、COX-2、 TNF-α 和 IL-1β 的表达量各不相同，当 cDHP-W1 预处理时间为 1 h、LPS 处理时间为 12 h 时，cDHP-W1 可显著下调 iNOS、COX-2、TNF-α 和 IL-1β 的表达。\nWestern Blot 分析表明，cDHP-W1 预处理 1 h 可有效抑制 LPS 激发的 p38、 ERK、JNK 的磷酸化和 IκB、p65 的核移位，提示 cDHP-W1 可通过抑制 LPS 激活的由 TLR4 介导的 NF-κB 和 MAPK 信号通路，从而抑制巨噬细胞炎性介质的表达与分泌。", "pub_time": "2018"}
{"sha256": "d704f27c7f8a6e6468be17aa5bdff34e7e9d06bca2a0a8feae9ea4995513304b", "doi": "", "title": "概念图在初中数学教学中的应用", "author": "孟梦 ", "keyword": "概念图, 初中数学教学, 教学实例, 实验研究", "abstract": "近几年，随着我国初中数学课程改革的实行推进，如何在提高课堂教学效率的同时，又能培养学生各方面的能力，成为教学者越来越关注的问题。根据新《数学课程标准》的要求：“数学学习应当是现实的、有意义的、富有挑战性的，有利于学生主动地进行观察、实验、猜测、验证、推理与交流等数学活动，动手实践、自主探索与合作交流是学生学习数学的重要方式”。很多学者提出了小组合作，分层教学等有效的教学手段，并进行研究，撰写了相关文献。然而从小学到初中，数学知识容量增加且变得抽象，加上混合编班，班级人数多，小组合作的实施显得较为困难。\n数学知识是呈现出网络结构的，数学概念、定义、算法、法则和定理之间都有一定联系。在教学中如果将数学知识用网络图呈现，则更能突出数学知识间的网络结构特征，这对数学教学也有积极作用。而概念图，可以通过形象直观的方式呈现出思维的过程和知识的关联，这对引导学生进行有意义的建构非常有帮助。所以利用概念图辅助制作教学设计，并且运用于课堂教学，可以提高课堂效率。\n本文首先对国内外概念图的相关研究成果和理论基础进行综述，然后结合理论基础对当前初中数学学科教学和教学实例进行分析。并通过实验教学，分析概念图在初中数学教学中的功能和影响，希望从中归纳概念图在数学教学中的应用策略，并进行研究总结。", "pub_time": "2017"}
{"sha256": "d706663fac5ab327f2af63393888b692f290c5ef099327207409ce2fb90ae9f2", "doi": "", "title": "新创企业动态能力与商业模式创新研究——基于制度环境的调节效应", "author": "胡涛", "keyword": "动态能力, 商业模式创新, 制度环境, 新创企业 ", "abstract": "伴随着网络经济的兴起，商业模式的概念被企业界所普遍接受，面对复杂和动荡的市场环境，以及日益加重的成本和竞争压力，持续不断地创新商业模式以适应市场变化成为新创企业获取竞争优势的制胜之道。以组织惯性和管理技能为基础的动态能力在企业感知市场机会、整合与重构企业内外部资源中发挥关键作用，帮助企业应对商业环境变化带来的影响，实现商业模式的调整与变革。然而，新创企业进行商业模型创新是一个复杂的演化过程，动态能力影响商业模式创新的机制依旧需要深入研究，动态能力的不同要素在商业模式创新过程中如何发挥作用还值得分析。为此，本文将基于动态能力视角，探究新创企业动态能力不同要素与商业模式创新的关系，并探讨制度环境在此过程中产生的影响。\n本文针对新创企业在商业模式创新实践中存在的现实问题和理论研究的不足，提出了动态能力、商业模式创新、制度环境之间关系的框架。根据动态能力理论的观点，本文提出新创企业之所以无法有效地实施商业模式创新，在于大多数企业对于动态能力的认知不足，无法充分利用其具有的动态能力来促进商业模式创新。通过分析机会识别能力、机会利用能力、资源重构能力、风险控制能力这四种动态能力对商业模式创新的影响，本文从理论上揭示了新创企业动态能力与商业模式创新内在联系。同时引入制度环境作为调节变量，将制度理论引入到动态能力理论的框架中，探究企业外部的制度环境如何影响动态能力与商业模式创新的关系。本文利用问卷调研获得的146个企业的样本数据对理论假设进行了实证验证。实证检验结果表明：（1）新创企业动态能力正向影响商业模式创新，且这种正向关系在动态能力的四个维度上均得到体现；（2）新创企业机会识别能力正向影响机会利用能力，机会利用能力在机会识别能力与商业模式创新之间起部分中介作用；（3）新创企业资源重构能力正向影响风险控制能力，风险控制能力在资源重构能力与商业模式创新之间起部分中介作用；（4）新创企业的机会利用能力、资源重构能力、风险控制能力与商业模式创新的关系不受制度环境影响，但制度环境正向调节机会识别能力与商业模式创新的关系。最后，本文基于相关研究结论，分别从新创企业和政府部门两个方面提出了相关建议。", "pub_time": "2020"}
{"sha256": "d706cf328624240d22f28520d90f71029b2c77ce7b2538293afdab2794cc3f0b", "doi": "", "title": "微纳结构铝基高能燃料的制备与燃烧性能", "author": "姜艾锋 ", "keyword": "球磨法, 铝纳米粒子, 纳米铝热剂, 微纳结构, 润湿性", "abstract": "随着科技的发展，中国航天事业迅速崛起。作为航天领域的“动力来源”，推进剂的选择成为了重中之重，因此推进剂组分的筛选便成为了研究重点。由于火箭推进过程需要较高的能量，因此具有高放热量的金属燃烧剂便被广泛研究。铝粉由于具有耗氧量低、燃烧热高、密度大、原材料丰富、成本较低等优点，在众多金属材料中脱颖而出。目前使用的多为微米铝粉，但微米铝粉有较厚的氧化层，这使得它的燃烧速率和燃烧效率都偏低，甚至还可能带来两相流损失、尾迹热辐射和喷管污染等问题，因此需要对铝粉进行纳米化和掺杂以提高其活性；另外，新制的纳米粒子具有极高的活性，一遇空气或水便立即自燃，因此需要将其表面稳定化以保存其能量；最后为了解决纳米粒子难以和其它组分均匀混合的问题，也需对其粒径、形貌和亲水性进行改善。\n首先，利用球磨技术对微米铝粉进行了纳米化研究，通过改变球磨助剂的种类、球磨助剂的添加量、球磨时间以及球料比等参数确定了高活性铝纳米粒子的制备工艺，并通过稳定化处理获得了类球形的、高比表面积的和可快速燃烧的核壳结构纳米粒子。结果表明，球磨时间的长短直接影响铝粉的活性，当球磨时间为14h，制备出的铝粉呈类球形，粒径约为30nm，比表面积超过30m2/g。此外，球磨14h的铝纳米粒子能够实现快速燃烧，产物在12V的电压下即可点燃且在2s内便可达到1000℃以上，而微米铝粉在25V的电压下仍无燃烧迹象。另外，使用乙烯基三甲氧基硅烷(A171)对纳米铝粉进行稳定化，相应的产物的热稳定性和疏水性都大大提高。\n为了进一步提高铝纳米粒子的燃烧性质，通过向铝纳米粒子中掺杂氧化类物质对其进行改性，分别使用原位球磨法和传统的超声共混法制备出了高活性的Al/Fe2O3纳米铝热剂，并对两组产物的结构和性质进行了对比。结果表明，原位球磨法制备的纳米铝热剂混合的均匀程度更高，而传统的超声共混法制备的纳米铝热剂混合的均匀性较差，甚至会出现各自团聚的现象。此外，原位球磨法制备并稳定化的纳米铝热剂的接触角为113.01°，明显大于相应的传统的超声共混法制备产物的接触角(96.54°)，表明原位球磨法所制备的纳米铝热剂更易于保存。通过原位球磨法制备的纳米铝热剂的最优掺杂Fe2O3量为17wt%，产物的氧化速率更快，起始燃烧温度更低，初始燃烧时所需的电压更低(12V)，明显低于传统的超声共混法制备产物的燃烧电压(15V)，并且燃烧火焰更稳定和均匀。\n在添加Fe2O3的基础上，又对掺杂FeF3的纳米铝热剂进行了研究，通过原位球磨技术制备了高活性的Al/FeF3纳米铝热剂，通过改变FeF3的添加量确定了Al/FeF3纳米铝热剂的制备工艺。结果表明，掺杂17wt%的FeF3样品最优。产物粒子呈类球形，平均直径为23.2nm，比表面积为26.33m2/g。另外，与未掺杂的铝纳米粒子和掺杂Fe2O3的纳米铝热剂相比，Al/FeF3纳米铝热剂的疏水性几乎没有变化，然而其初始氧化温度更低，燃烧速率更快。说明掺杂氧化类元素能够提高铝纳米粒子的燃烧性能，且所掺杂元素的氧化性越强，其提高铝纳米粒子燃烧性能的效果越明显。\n利用自制的溶剂挥发法技术对微纳结构粒子的构造进行了研究，最优的产物粒子呈现球形杨梅状，粒径分布均匀且平均粒径约为10μm。制备的产物不仅保留了纳米铝热剂本身在热稳定性及燃烧方面等优异性质，其疏水角也比相应的纳米铝热剂减少了54.7%(115.12°→52.20°)，大幅度地增加粒子的流动性和润湿性，进而提高了其应用在推进剂组分中的可能性。", "pub_time": "2020"}
{"sha256": "d70774f460b009913ad4833f461ea2e31da534b6e8f53c600e06ed8997d0cbfd", "doi": "", "title": "城乡结合地区初中生化学元素观的构建", "author": "马小洪", "keyword": "化学元素观, 初中化学, 化学基本观念 初中化学教材, 城乡结合地区", "abstract": "笔者经过调查发现城乡结合地区的学生在初中毕业后能够升入普通高中继续学习化学课程的人数比较少；学生的学习兴趣比较低下，缺乏学习热情。大多数学生在初中毕业后只能进入没有开设化学课程的中等职业技术学校学习，意味着上述地区的大多数学生能够学习化学课程的时间只有短短的一年。然而，九年义务教育新课程目标明确要求学生在学习化学课程以后，能够从以化学的眼光认识自然、社会和环境；会利用化学手段和方法解决实际问题。因此，需要在教学过程中帮助学生进行观念的构建，养成从化学的角度分析看待事物的习惯。本文回归教材，从城乡结合地区的学生获取化学知识的主要途径入手，分析化学元素观在初中化学课程中的具体内涵；挖掘元素观在教材具体章节知识中的体现和建构体系；结合教学经验立足于该类地区的实际情况提出具有针对性的帮助学生构建化学元素观的教学方法：\n把握初三年龄阶段学生的发展认知规律，以恰当的方式激发学生在学习化学学科方面的兴趣；对教材中较难知识点进行分散处理，由浅入深的进行教学；将元素概念史渗透到教学过程中发挥其价值；在学生已有生活经验之上创设教学情境；充分利用课本中的学生体验活动，消除学生在学习过程中出现的疑惑和枯燥感；充分利用现代化的仿真教学平台构建思维导图，拓展学生的活动空间等。\n根据维果茨基的最近发展区理论，设计了人教版九年义务教育化学教材第三单元元素的教学案例，将提出的构建学生元素观的方法应用到教学中。大多数学生通过学习掌握了教材中元素的概念；能够快速的区分元素和原子；会利用元素符号表示常见的元素；理解了元素符号的意义；会利用元素周期表查找指定元素的信息；能够在教师的引导下梳理本课题的知识框架并画出思维导图；会从元素的角度分析看待事物。实现了教学目标的达成与元素观构建相结合，学生在跳一跳够的着的状态下轻松愉快的学习，达到教学要求的同时实现了观念的转变和构建，科学素养在一定程度上得到了提升。", "pub_time": "2015"}
{"sha256": "d7077d3a556c7a7bab84ea07db6c835ab29fae2c8d8d276d11bdbfeb98b012aa", "doi": "", "title": "课例研究促进幼儿教师教学能力发展的个案研究", "author": "陈志玲", "keyword": "课例研究, 幼儿教师, 教学能力 ", "abstract": "幼儿教师教学能力是决定幼儿教育教学活动有效的关键因素，不仅关系到幼儿教师自身专业发展，还关系到幼儿的学习与发展。经研究表明，课例研究是基于真实课堂教学，在有效教学理念下对教师行为有效地研究，帮助教师达成专业成长的目标。然而，在当下幼儿园的课例研究中，对课例研究价值大都围绕促进幼儿教师专业成长，《幼儿教师专业标准（试行）》中的教师各种能力是怎样发展的？哪些能力可以较快发展起来？哪些能力需要时间的延续？在课例研究中都比较笼统。因此，当下幼儿园课例研究需要寻找新的突破口，解决幼儿教师教学能力的发展问题。\n本研究从课例研究的视角研究幼儿教师教学能力发展的变化过程，采用个案研究法。描述了“体验式”课例下突破教师活动准备能力、“参与式”课例下提高教师活动实施能力、“换位式”课例下整合教师教学能力的课例研究过程。之后，研究结合《幼儿教师教学能力评价表》对六名幼儿教师活动准备能力、活动实施能力以及活动总结能力进行分组前、后测，验证课例成效。\n本研究在对课例研究的解读过程中，结合测查法，对教研组教师和非教研组教师进行的独立样本T检验和配对样本T检验，结果分析得出：课例研究中幼儿教师教学能力从整体上都得到了较大发展。还发现，课例研究中幼儿教师教学能力发展机制是课例研讨具体情境中问题引发幼儿教师关于目标和设计的认知冲突，基于专业共同体下形成以学为中心，在诊断、反思的作用下相互促进、相互融合，最终实现幼儿教师教学能力的发展。", "pub_time": "2018"}
{"sha256": "d708b9727c81e62d579e04be2a65b1485dc18c0ebba8590828c449d53d2911be", "doi": "", "title": "Ｚ银行安徽分行银医业务服务营销策略研究", "author": "周璐", "keyword": "银医合作, 产品定位, 营销策略", "abstract": "随着利率市场化改革的不断加深，各项信息化技术的不断发展，市场竞争的急速加剧，商业银行与各单位的合作模式趋向专业化，服务内容精细化，因此，为了有效地营销医疗单位，各家商业银行也针对性地推出了专业化的银医合作模式。所谓的银医合作，指的是银行与医院行业，在互联网高速发展的情况下，利用不断成熟的互联网技术和支付技术，结合银行的金融领域的业务，从而赢得医院的公司业务受理权限，推广自身金融产品，拓宽银行客户群，为医院提供更加快捷、安全的结算方式和专业化的金融服务，最终获得双赢的合作模式。\n随着人口环境的压力不断增大，老百姓对医疗水平的要求不断提升，就医难的问题也愈发突出，因此我国卫生部提出“三好一满意”活动的分解指标，即“服务好、质量好、医德好，群众满意”活动，并在全国各级医疗机构开展。因此，通过银医合作模式的升级带动就诊模式的技术改造，对实现各级医疗单位就诊结算流程的整合、提升民生医疗服务质量和效率，达成“三好一满意”的民生建设目标，具有重要意义。\n虽然ｚ银行安徽分行目前已经意识到了营销策略在银医合作业务中的重要性，并通过营销环境评估、产品设计等方面做了许多工作，但就营销的结果来看，仍然存在银医合作模式单一、产品服务同质化严重、缺乏有效的营销渠道、服务质量下降、过程管理流程复杂、物质环境不满足需求等问题。\n本文通过对ｚ银行安徽分行银医业务服务进行详细分析，了解安徽银医市场的竞争情况和客户对银医业务服务、技术的需求，设计符合顾客导向的营销战略，创造新的合作契机。再结合Ｚ银行安徽分行银医业务一直以来发展的营销优势，修正目前存在的营销劣势，识别和定位目标市场，通过差异化的银医合作服务新模式，形成竞争优势和品牌效应，最终通过创新的产品战略和多渠道的营销传播组合，达到营销目标。\n本文的第一章将对论文的研究背景、国内发展现状、研究目的和意义、研究思路和方法、研究创新点进行了阐述，了解当前ｚ银行安徽分行银医业务服务的发展现状和研究其营销策略的重要性；第二章详细介绍了本论文应用的相关理论基础；第三章运用７Ｐ营销理论对Ｚ银行安徽分行银医业务服务的基本情况进行了介绍，分析了其存在的营销问题和产生问题的原因；第四章通过ＰＥＳＴ分析对Ｚ银行安徽分行银医合作业务服务的营销宏观环境进行了分析，并对其在安徽银医市场上的竞争者情况和客户需求进行了详细分析，再通过ＳＷＯＴ分析方法，了解Ｚ银行安徽分行在银医业务服务的优缺点；第五章通过综合分析的结论有针对性地对Ｚ银行安徽分行银医业务服务提出营销策略建议，分别对产品策略、价格策略、促销策略、渠道策略、人员策略、过程管理策略、有形展示策略一一进行阐述，同时对如何保证以上策略的实施提出了保障性建议。以实现稳定和发展Ｚ银行安徽分行在银医业务服务的营销目标。", "pub_time": "2019"}
{"sha256": "35ae2e40504df429ddcf791323f3feddab4cb786329271b107a0f71e773f0114", "doi": "", "title": "配料秤在包钢烧结厂的应用", "author": "郝建军", "keyword": "配料秤, 标定, 应用, 烧结, 配料", "abstract": "论述了烧结配料过程中的检测技术，标定的方法及自动配料的方式，并对现有的问题进行了说明。", "pub_time": "1999"}
{"sha256": "35aedf8e99a1a9f2649b627167cfb7bfba160f01967dfef2214c426699bcff60", "doi": "", "title": "出三招除腐败", "author": "吴昌鸿", "keyword": "", "abstract": "", "pub_time": "2000"}
{"sha256": "35b10762258eb26d6292bae6636e61c4af136fe1a96ecfd5b7cab0b5ced7467c", "doi": "", "title": "森林生物多样性与林木害虫的自然防治", "author": "谷昭威, 曲爱军, 朱承美", "keyword": "biodiversity, natural control", "abstract": "The relationship between forest biodiversity and natural control of tree pests is analysed and natural control of harmful insects in plantation ecosystem is discussed in the paper.", "pub_time": "1998"}
{"sha256": "35b17a232566d1c2389551460f52ad234ba6c593e2489ba2625d7f32b9c1ca68", "doi": "", "title": "莫高窟保护档案数据库系统", "author": "王宝义, 侯文芳", "keyword": "", "abstract": "", "pub_time": "1996"}
{"sha256": "35b1f2c1096e3eb54c65fd6990e0f6b4f9e1a38ddd3b390e64ed13a84ae11e4b", "doi": "", "title": "码域滤波的基本原理", "author": "王艺, 赵明, 杜志敏, 吴伟陵", "keyword": "信号处理, 多用户检测, 码变换阵, 离散码变换对", "abstract": "本文基于DS-CDMA系统中的线性多用户检测提出了码变换、离散码变换时的概念，主要阐述了时域滤波的基本原理，指出线性多用户检测是一种码/时域滤波，但有关码变换的研究仍有待深入。", "pub_time": "2001"}
{"sha256": "35b465bce34684f3cce245160c9ef9d4bc684e5f2138a1faaaecda7d11e13a0f", "doi": "", "title": "现代国有企业制度论略\n——对国有企业活力与企业制度改革的分析", "author": "孟庆琳", "keyword": "", "abstract": "", "pub_time": "1997"}
{"sha256": "35b5b5dffb729e8ddf00f1865322ca3399f34b5d1a358e664c530e10795aca14", "doi": "", "title": "小剂量氯胺酮静脉麻醉用于人工流产术20例临床观察", "author": " 柳少君", "keyword": "", "abstract": "", "pub_time": "2001"}
{"sha256": "35b89425ec48492655b766c9adef57466b622963f3522d7c4a9ee45cd676926b", "doi": "", "title": "单线自动循环脱挂式厢式客运索道的维修", "author": "方旭东", "keyword": "单线循环脱挂式, DOPPELMAYR, 故障, 维修", "abstract": "本文详细介绍了黄山玉屏索道——从奥地利DOPPELMAYR公司引进的单线循环脱挂式厢式客动索道自投入运行以来所碰到的各种故障，以及为排除这些故障所采取的技术措施。可供同类索道从事设备维修的人员参考。", "pub_time": "2001"}
{"sha256": "362195f40b442b6e1590448c0582f6305c2ed09592af38ede9a1e70e739db7fe", "doi": "10.1146/annurev-anthro-102218-011044", "title": "How Maya Archaeologists Discovered the 99% Through the Study of Settlement Patterns", "author": "Jeremy A. Sabloff", "keyword": "Maya, archaeology, settlement patterns, elite, commoners, landscapes", "abstract": " Thisarticle presents an autobiographical perspective on the changing nature of Maya archaeology, focusing on the role of settlement pattern studies in illuminating the lives of commoners as well as onthetraditional emphasis on the ruling elite. Advances in understanding the nature of nonelite peoples in ancient Maya society are discussed,as are the many current gaps in scholarly understandings of pre-Columbian Maya civilization, especially with regard to the diversity of ancient “commoners”and the difficulty in analyzing them as a single group", "pub_time": "2019"}
{"sha256": "6c09d572147e53da1884b66da484b21c088751bc89880400ff69e25aa9f290c1", "doi": "10.1146/annurev-psych-010814-015135", "title": "Causality in Thought", "author": "Steven A. Sloman, David Lagnado", "keyword": "causal reasoning, causal judgment, causal decision making, causal attribution", "abstract": " Causal knowledge plays a crucial role in human thought, but the nature of causal representation and inference remains a puzzle. Can human causal inference be captured by relations of probabilistic dependency, or does it drawonricherformsofrepresentation?Thisarticleexploresthisquestionby reviewingresearchinreasoning,decisionmaking,variousformsofjudgment, and attribution. We endorse causal Bayesian networks as the best normative framework and as a productive guide to theory building. However, it is incomplete as an account of causal thinking. On the basis of a range of experimentalwork,weidentifythreehallmarksofcausalreasoning—therole of mechanism, narrative, and mental simulation—all of which go beyond mere probabilistic knowledge. We propose that the hallmarks are closely related. Mental simulations are representations over time of mechanisms. When multiple actors are involved, these simulations are aggregated into narratives", "pub_time": "2014"}
{"sha256": "36781acd1d7c275c37b4121c4372f0c6880056149cfe0fc9e31014c5cfb40d7d", "doi": "10.1146/annurev-physiol-021317-121615", "title": "The Evolving Understanding of Dopamine Neurons in the Substantia Nigra and Ventral Tegmental Area", "author": "Stephanie C. Gantz, Christopher P. Ford, Hitoshi Morikawa, John T. Williams", "keyword": "pacemaker, bursting, synaptic transmission, dendritic transmission, intrinsic properties, plasticity", "abstract": " Inrecentyears, thepopulationofneurons intheventral tegmental area (VTA)andsubstantianigra(SN)hasbeenexaminedatmultiplelevels.The resultsindicatethattheprojections,neurochemistry,andreceptorandion channelexpressioninthiscellpopulationvarywidely.Thisreviewcenters ontheintrinsicpropertiesandsynapticregulationthatcontroltheactivity ofdopamineneurons.Althoughalldopamineneuronsfireactionpotentials inapacemakerpatternintheabsenceofsynapticinput,theintrinsicprop ertiesthatunderliethisactivitydifferconsiderably.Likewise,thetransition intoaburst/pausepatternresults fromcombinationsof intrinsicioncon ductances, inhibitoryandexcitatorysynapticinputsthatdifferamongthis cellpopulation.Finally,synapticplasticityisakeyregulatoroftherateand patternofactivityindifferentgroupsofdopamineneurons.Throughthese fundamentalproperties, theactivityofdopamineneuronsisregulatedand underliesthewide-rangingfunctionsthathavebeenattributedtodopamine.", "pub_time": "2017"}
{"sha256": "0070b1bc393784870581aa9a7f2a94bcd0d97d345a5fbf1ebf44be49eb32515c", "doi": "10.1146/annurev-ecolsys-102220-011451", "title": "Consistent Individual Behavioral Variation: What Do We Know and Where Are We Going?", "author": "Kate L. Laskowski, Chia-Chen Chang, Kirsten Sheehy, Jonathan Aguiñaga", "keyword": "animal personality, behavioral syndromes, temperament, coping styles", "abstract": "The study of individual behavioral variation, sometimes called animal personalities or behavioral types, is now a well-established area of research in behavioral ecology and evolution. Considerable theoretical work has developed predictions about its ecological and evolutionary causes and consequences, and studies testing these theories continue to grow. Here, we synthesize the current empirical work to shed light on which theories are well supported and which need further refinement. We find that the major frameworks explaining the existence of individual behavioral variation, the pace-of-life syndrome hypothesis and state-dependent feedbacks models, have mixed support. The consequences of individual behavioral variation are well studied at the individual level but less is known about consequences at higher levels such as among species and communities. The focus of this review is to reevaluate and reestablish the foundation of individual behavioral variation research: What do we know? What questions remain? And where are we going next?", "pub_time": "2022"}
{"sha256": "6cb2e13a09d12189b0225ed8b7c11b62bffb4563a3286254da3bdcd4fb1613e6", "doi": "10.1146/annurev-economics-080218-02590", "title": "Capital Flows and Leverage", "author": "Sebnem Kalemli-Özcan, Jun Hee Kwak", "keyword": "capital flows, leverage, intermediation, banking flows, corporate debt", "abstract": " This article surveys the literature on capital flows and leverage. We summa rize results from the existing papers and document new facts. The empirical literature takes both a macro and a micro approach.The macroapproachfo cuses on aggregate data both over time and in the cross-section of countries, andit documentsapositivecorrelation between total capital flows,build-ups in terms of external and domestic debt to GDP ratio, and financial crises. The micro approach uses granular data and focuses on leverage at the firm and bank level and associates this leverage with country-level capital flows and related exchange rate movements. We document new facts from a hy brid approach that focuses on the relationship between sector-level capital f lows and sectoral leverage. We highlight the interconnections between dif ferent approaches and argue that harmonization of the macro and micro approaches can yield a more complete understanding of the effect of capital f lowsoncountry-,sector-,and firm- and bank-level leverage associated with credit booms and busts", "pub_time": "2020"}
{"sha256": "00a1122e18c2e6fa5b3ff9ddca4134192a150ed9b6074754f52bb531ebab98c5", "doi": "10.1146/annurev-animal-020518-115206", "title": "One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development", "author": "Constance E. Clare, Amey H. Brassington, Wing Yee Kwong, Kevin D. Sinclair", "keyword": " folate, vitamin B12, epigenetics, genetic variants, DNA methylation, Developmental Origins of Health and Disease, assisted reproduction", "abstract": " One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that include the methionine and folate cycles that are central to cellular function, providing 1C units (methyl groups) for the synthe sis of DNA, polyamines, amino acids, creatine, and phospholipids. S adenosylmethionine is a potent aminopropyl and methyl donor within these cycles and serves as the principal substrate for methylation of DNA, asso ciated proteins, and RNA. We propose that 1C metabolism functions as a key biochemical conduit between parental environment and epigenetic reg ulation of early development and that interindividual and ethnic variability in epigenetic-gene regulation arises because of genetic variants within 1C genes, associated epigenetic regulators, and differentially methylated tar get DNA sequences. We present evidence to support these propositions, drawing upon studies undertaken in humans and animals. We conclude that future studies should assess the epigenetic effects of cumulative (multigener ational) dietary imbalances contemporaneouslyinbothparents,asthisbetter represents the human experience", "pub_time": "2018"}
{"sha256": "a2da5b266942efb51ddc94d83776de56791717d7b274cccb8e75d1d624568c7d", "doi": "10.1146/annurev.biophys.31.082901.134147", "title": "MY ROAD TO BIOPHYSICS: Picking Flowers on the Way to Photosynthesis", "author": "George Feher", "keyword": "EPR, ENDOR, fluctuation spectroscopy, nuclear polarization, bacterial photosynthesis, protein crystallization", "abstract": "", "pub_time": "2002"}
{"sha256": "35a18890e329bbf1ed029e4bbfc4c59ceaf5f92055336012ee0bf814e9fdb2a0", "doi": "", "title": "Single-Crystal Infrared Detectors Based Upon Intrinsic Absorption", "author": "F. F. RIEKEt, L. H. DEVAUX, A. J. TUZZOLINO", "keyword": "", "abstract": "", "pub_time": "1959"}
{"sha256": "35a1b3287acb9098f7e35c8aafb2c90b8531f2b49c515b8b11734ed295a73d72", "doi": "10.1016/j.jclepro.2021.126027", "title": "Energy transition and the role of system integration of the energy, water and environmental systems", "author": "Hrvoje Mikulčić, Jakov Baleta, Jiří Jaromír Klemes, Xuebin Wang", "keyword": "Energy transition, Decarbonisation, Sustainability, System integration, Climate change", "abstract": "Time is running out, while it is becoming obvious that many countries may fail to meet Paris Agreement goals. More intensive efforts should be invested with a strong emphasis on emissions decarbonisation of all sectors and energy transition towards more renewable energy sources. This work provides an overview of the impact of the energy transition on the environment, energy and water systems and the need for integration of these systems. Reduction of carbon-related emissions has been identified as the common topic through reliance on the circular economy concept, taking into account the economic dimension in an attempt to decouple economic growth from emissions. Advanced control concepts, mathematical modelling and integration of renewable energy sources with carbon capture and storage and sewage sludge treatment can be recognised as dominant topics through the recognition that energy transition offers a solution to emission problem, but raises further challenges by introducing disbalance between supply and demand side of energy systems. It is expected that present contribution will identify dominant trends under the common divisor of the energy transition and foster discussion among the experts for future studies.", "pub_time": "2021"}
{"sha256": "35a5be361015bda47d0f1faf6518ed3c7e6972839fd46bcd9add7abca1efdf67", "doi": "10.5194/amt-16-4723-2023", "title": "Development of low-cost air quality stations for next-generation monitoring networks: calibration and validation of NO₂ and O₃ sensors", "author": "Alice Cavaliere, Lorenzo Brilli, Bianca Patrizia Andreini, Federico Carotenuto, Beniamino Gioli, Tommaso Giordano, Marco Stefanelli, Carolina Vagnoli, Alessandro Zaldei, and Giovanni Gualtieri", "keyword": "", "abstract": "A pre-deployment calibration and a field validation of two low-cost (LC) stations equipped with O₃ and NO₂ metal oxide sensors were addressed. Pre-deployment calibration was performed after developing and implementing a comprehensive calibration framework including several supervised learning models, such as univariate linear and non-linear algorithms, and multiple linear and non-linear algorithms. Univariate linear models included linear and robust regression, while univariate non-linear models included a support vector machine, random forest, and gradient boosting. Multiple models consisted of both parametric and non-parametric algorithms. Internal temperature, relative humidity, and gaseous interference compounds proved to be the most suitable predictors for multiple models, as they helped effectively mitigate the impact of environmental conditions and pollutant cross-sensitivity on sensor accuracy. A feature analysis, implementing dominance analysis, feature permutations, and the SHapley Additive exPlanations method, was also performed to provide further insight into the role played by each individual predictor and its impact on sensor performances. This study demonstrated that while multiple random forest (MRF) returned a higher accuracy than multiple linear regression (MLR), it did not accurately represent physical models beyond the pre-deployment calibration dataset, so a linear approach may overall be a more suitable solution. Furthermore, as well as being less computationally demanding and generally more suitable for non-experts, parametric models such as MLR have a defined equation that also includes a few parameters, which allows easy adjustments for possible changes over time. Thus, drift correction or periodic automatable recalibration operations can be easily scheduled, which is particularly relevant for NO₂ and O₃ metal oxide sensors. As demonstrated in this study, they performed well with the same linear model form but required unique parameter values due to intersensor variability.", "pub_time": "2023"}
{"sha256": "35a83a0b25805268241fcf9c205a3d2bdffe060d4f34b5bed46b408510bbc286", "doi": "", "title": "Membership datoriale e contrattazione collettiva in Italia: evidenze empiriche da un’indagine INAPP ", "author": "FRANCESCA BERGAMANTE, MANUEL MAROCCO", "keyword": "two-tier system of bargaining; decentralisation of collective bargaining; Italian firms", "abstract": "Decentralization of collective bargaining is considered a key element to introduce innovations and changes work’s organization. Since 2011, European institutions too have promoted the dissemination of collective agreements more sensitive to corporate market conditions.\nWhat is the role of employer’s associations in this context? The article intends to provide an analysis in this regard, using data from the INAPP-RIL survey conducted on a sample of about 26,000 Italian firms. After studying the trend of membership rates and membership density over time, as well as the determinants that influence membership, the article focuses on the latter's influence on the dissemination and coverage of collective cross-sector bargaining.\nOn the basis of the main evidence contained in the descriptive analyses, it may seemingly be stated that the barycentre of the Italian collective bargaining system - the «National Collective Labour Agreement» - has not been affected by the European, legislative and social partners “multilevel” drive in favour of its decentralisation.\nIndeed the multi-employer bargaining has continued to be applied outside of an association membership logic: there has been an increase in the share of firms that state to apply a sectoral agreement spontaneously, without joining an Employers’ Association. The Employers’ Association fragmentation is a context which conceals the proliferation of the so called Pirate Agreements, that is a system characterised by a self-opting out of the collective agreement.\nAt the same time, and perhaps for the same reasons, second-level bargaining is at a standstill. In fact, traditional motivations related to competitiveness continue to make it preferable for small and medium sized firms to maintain the centrality of the national sectoral collective agreement.", "pub_time": "2018"}
{"sha256": "35a91652764e1c9833973011f759515e2be020cd22a7dd30206c556e186890c6", "doi": "10.1039/C6CC02729F", "title": "A New Approach for the Facile Preparation of Metal–Organic Framework Composites Directly Contacting with Metal Nanoparticles through Arc Plasma Deposition", "author": "Masaaki Sadakiyo, Shotaroo Yoshimaru, Hidetaka Kasai, Kenichi Kato, Masaki Takata, Miho Yamauchi", "keyword": "", "abstract": "The arc plasma deposition (APD) method is first applied to prepare metal–organic framework (MOF) composites loading metal nanoparticles having a direct contact with the MOF. We demonstrate the detailed growth mechanism of metal particles on the MOFs and the applicability of the APD for various combinations of metals and MOFs.", "pub_time": "2016"}
{"sha256": "a5162943bb1c6f04de16c4e36ebeb5e2ff57ffcb3a31120fff6b930d126c2d72", "doi": "10.1128/mBio.03471-20", "title": "Gene Replacement by a Selectable Marker in the Filamentous Fungus Magnaporthe oryzae", "author": "Nalleli Garcia, Alexa N. Farmer, Richmond Baptiste, Jessie Fernandez", "keyword": "Magnaporthe oryzae, Primer design, Protoplast transformation, Gene deletion, Split marker, Homologous recombination, ILV1, Hygromycin, DNA extraction", "abstract": "Magnaporthe oryzae is a filamentous fungus responsible for the detrimental rice blast disease afflicting rice crops worldwide. For years, M. oryzae has served as an excellent model organism to study plant pathogen interactions due to its sequenced genome, its amenability to functional genetics, and its capacity to be tracked in laboratory settings. As such, techniques to genetically manipulate M. oryzae for gene deletion range from genome editing via CRISPR-Cas9 to gene replacement through homologous recombination. This protocol focuses on detailing how to perform gene replacement in the model organism, M. oryzae, through a split marker method. This technique relies on replacing the open reading frame of a gene of interest with a gene conferring resistance to a specific selectable chemical, disrupting the transcription of the gene of interest and generating a knockout mutant M. oryzae strain. ", "pub_time": "2023"}
{"sha256": "dc9e0a84cca7277acdabeefeaf24f5bc57bffadaa2db2470d0060b70b8e5ec28", "doi": "10.21769/BioProtoc.3413", "title": "Implementing VIPER for Imaging Cellular Proteins by Fluorescence Microscopy", "author": "Julia K. Doh, Caroline A. Enns, Kimberly E. Beatty", "keyword": "Protein tag, Fluorescence, Labeling, Microscopy, Cell biology, Peptide, Biochemistry", "abstract": "Genetically-encoded tags are useful tools for multicolor and multi-scale cellular imaging. Versatile Interacting Peptide (VIP) tags, such as VIPER, are new genetically-encoded tags that can be used in various imaging applications. VIP tags consist of a coiled-coil heterodimer, with one peptide serving as the genetic tag and the other (“probe peptide”) delivering a reporter compatible with imaging. Heterodimer formation is rapid and specific, allowing proteins to be selectively labeled for live-cell and fixed-cell imaging. In this Bio-Protocol, we include a detailed guide for implementing the VIPER technology for imaging receptors on live cells and intracellular targets in fixed cells. This protocol is complemented by two other Bio-Protocols outlining the use of VIPER (Doh et al., 2019a and 2019b).", "pub_time": "2019"}
{"sha256": "3acf00d1b1c899d348d650707b8807a00647ff17d0d88a377ddf2fa4137b9a10", "doi": "10.21769/BioProtoc.4471", "title": "Isolation and ex vivo Expansion of Limbal Mesenchymal Stromal Cells", "author": "Naresh Polisetti, Lyne Sharaf, Thomas Reinhard, Günther Schlunck", "keyword": "Limbal mesenchymal stromal cells, Limbal niche cells, Limbal stem cells, Cornea, Isolation, Expansion", "abstract": "Limbal mesenchymal stromal cells (LMSC), a cellular component of the limbal stem cell niche, have the capability of determining the fate of limbal epithelial progenitor cells (LEPC), which are responsible for the homeostasis of corneal epithelium. However, the isolation of these LMSC has proven to be difficult due to the small fraction of LMSC in the total limbal population, and primary cultures are always hampered by contamination with other cell types. We recently published the efficient isolation and functional characterization of LMSC from the human corneal limbus using CD90 as a selective marker. We observed that flow sorting yielded a pure population of LMSC with superior self-renewal capacity and transdifferentiation potential, and supported the maintenance of the LEPC phenotype. Here, we describe an optimized protocol for the isolation of LMSC from cadaveric corneal limbal tissue by combined collagenase digestion and flow sorting with expansion of LMSC on plastic. ", "pub_time": "2022"}
{"sha256": "d71d94c22e2668d062648a93f715703424d07138283359b8d80320fdb715ae74", "doi": "10.21769/BioProtoc.3645", "title": "Primed Track: Reliable Volumetric Single-cell Tracking and Lineage Tracing of Living Specimen with Dual-labeling Approaches", "author": "Maaike Welling, Konstantinos Kalyviotis, Periklis Pantazis", "keyword": "Pre-implantation embryos, Mouse, Lineage tracing, Tracking, Primed conversion, Photoconvertible proteins, Live imaging, Dual color fluorescent labeling", "abstract": "Mammalian embryonic development starts with a single fertilized zygote that develops into a blastocyst embryo consisting of three cell types that evolve into either embryonic or extra-embryonic tissues. Lineage tracing of these cells can provide important information about the molecular and cellular dynamics contributing to fate allocation during early development. While global labeling techniques allow for visualization of all cells at the same time, lineage tracing of cells over several divisions can become complicated due to embryo movement and rotation as well as increasing cell densities. Here, we use green-to-red photoconvertible proteins for both global and sparse labeling of cells of interest in the developing murine embryo. We use primed conversion to achieve precise photoconversion of single nuclei in 4-cell stage embryos followed by volumetric live imaging to capture development up to the blastocyst stage. We developed an image analysis pipeline, called primed Track, that uses the dual labeling strategy for both straightforward segmentation and registration of all cells in the embryo as well as correction of rotational and spatial drift. Together, this strategy allows for reliable and fast tracking and lineage tracing of individual cells, even over increased imaging time intervals that result in a major reduction in data volume, all essential conditions for volumetric long-term imaging techniques.", "pub_time": "2020"}
{"sha256": "0441600e204e85326828a8995ae699a317480336c193ce517793752dffc5b4f1", "doi": "10.21769/BioProtoc.2896", "title": "Increasing the Membrane Permeability of a Fern with DMSO", "author": "Marcelo Garcés", "keyword": "Filmy ferns, Membrane permeability, DMSO, Propidium iodide", "abstract": "Cell membrane prevents the entrance of extra molecules (e.g., transcription and translation inhibitors) into the cell. For studying the physiological effects of transcription and translation inhibitors on Hymenophyllum caudiculatum fronds, we incubate fronds with 0.1% DMSO to test if this increases cell membrane permeability relative to incubation with ultrapure water. The study showed that DMSO could significantly improve the cell membrane permeability of filmy fronds.", "pub_time": "2018"}
{"sha256": "35a52fd77dc9ad0f3dae57d46676004de3fa791e22a8bb3110c6e2399451fa0b", "doi": "", "title": "Y Ferch ym Myd y Faled Delweddau o’r ferch ym maledi’r ddeunawfed ganrif", "author": "Siwan M. Rosser", "keyword": "", "abstract": "", "pub_time": "2005"}
{"sha256": "001585cba71e638f510371f46e9a1816eca10eef579812133b62128de54ffb44", "doi": "", "title": "The Imam’s Daughter", "author": "Hannah Shah ", "keyword": "", "abstract": "", "pub_time": "2009"}
{"sha256": "d7084e97125a83346bea6ebf3afa074021daca3b14c15c5619fe52323a8f0ea7", "doi": "", "title": "Scandalizing Jesus?: Kazantzakis's The last temptation of Christ fifty years on", "author": "Darren J. N. Middletori", "keyword": "", "abstract": "", "pub_time": "2005"}
{"sha256": "6b3625d134b8ef74db37c976614c8cf8ca67ee5c941cde9a05f5a2cdaf9f8614", "doi": "", "title": "Rydin’ the Storm Out", "author": "P.J. Fiala", "keyword": "", "abstract": "", "pub_time": "2015"}
{"sha256": "6b3d33738a71764f6f802bedb47700844e635e38440ffbee1afc295935f2b892", "doi": "10.1007/978-3-662-61709-0 ", "title": "Heilung oder Humbug? 150 alternativmedizinische Verfahren von Akupunktur bis Yoga", "author": "Edzard Ernst", "keyword": "", "abstract": "", "pub_time": "2021"}
{"sha256": "d6bbee2d21023531df2a5d24cba21a28f320d9f2b598f7d0f2b3675a5171be59", "doi": "", "title": "Office of Kink and Karma: Tri Me", "author": "Celia Kyle", "keyword": "", "abstract": "", "pub_time": "2007"}
{"sha256": "35b7b8b669ef87846f7deb00bbb58e3da42b93778ee03d35058fa5242752c814", "doi": "", "title": "RUNNING TO PARADISE Yeats's Poetic Art", "author": "M. L. ROSENTHAL ", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35b89cd33f4172b242afa4bc9e5c5b32cff740d445ce7309368cf8439035e275", "doi": "", "title": "The war at home : a wife’s search for peace (and other missions impossible) ", "author": "Rachel Starnes ", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35b8a446f1fd71ce42a5e29b6ccd300a1ee0273d312e1251a8aa8185554d84df", "doi": "", "title": "Careers for Legal Eagles & Other Law-and-order Types VGM Careers for You Series", "author": "Camenson, Blythe", "keyword": "", "abstract": "", "pub_time": "1998"}
{"sha256": "35c1b013c1989652be81a461dc8a059f192f152870a096c80a612e8c2d8d1f04", "doi": "", "title": "The Enthusiast’s Guide to DIY Photography", "author": "MIKE HAGEN ", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35d673c4d6ab31d6b8de3db5ae04b264f9d5739603984ae3255adb2df7ab020b", "doi": "", "title": "ENGENDERING A NATION A feminist account of Shakespeare’s English histories", "author": "Jean E.Howard, Phyllis Rackin", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "a104d69555301cf9be06d7bda6158b5cadec16a19906a474399a6a67b55215d9", "doi": "", "title": "The Book of the Links\na Symposium on Golf", "author": "Martin H.E Sutton, Bernard Darwin, H.S. Colt", "keyword": "", "abstract": "The Book of the Links features selected writings from prominent golf figures of the early 20ᵗʰ century, including Martin H.E Sutton, Bernard Darwin, and H.S. Colt. Written in 1912, this collaborative guide provides rare insight into the methods and philosophies that were used to design, construct, and maintain the world’s most renowned golf courses.\nAccording to Sutton, “In producing this volume, it has been my aim to provide in the first instance a compendium of information, of a more complete character than has before been compressed into a single volume, on all the points upon which golf secretaries, green committees, and greenkeepers desire instruction.” \nInside this classic of golf literature, the authors detail the essential features of an ideal golf course and provide insight on the proper methods of greenkeeping and design. Along with their first-hand narrative, all of the original photos and sketches have been included, ensuring that every element of the first edition has a been carefully preserved.", "pub_time": ""}
{"sha256": "a0f3a35bb6383441a4e559a6e1c180c7499f991db5fb60a2a8bab2d62f7c60f2", "doi": "", "title": "Ressources minérales et énergie dans le contexte de la transition énergétique", "author": "Olivier Vidal", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "a0f488a74157fc390db97426da5b16ff889f9ae2b3af45e1ca485421cbdc176b", "doi": "", "title": "Love Lasts Forever", "author": "Dominiqua Douglas", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "a0f74e8e8632ad7aaa9fa12c59407d1a223994ff942330162ff36de0213162fe", "doi": "", "title": "It's Not Me, It's You", "author": "Mhairi McFarlane", "keyword": "", "abstract": "", "pub_time": "2014"}
{"sha256": "6b5c3f836c1196a4afd67744a7f338a9f2f3def74ef161d9281b8240b7856acd", "doi": "", "title": "PREGNANT ON THE UPPER EAST SIDE?", "author": "Emilie Rose", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "a14a07bb39699f3fa068d5b57357d23c2ab0985a78d1af4e1095bb0e7b5c0017", "doi": "10.3790/vjh.81.2.199", "title": "Kann die Riester-Rente die Absenkung des Rentenniveaus kompensieren?", "author": "Tim Köhler-Rama", "keyword": "Pension reform in Germany, Riester pension, Riester subsidy", "abstract": "Eine sozialpolitische Bewertung der Riester-Förderung ist auf der Grundlage der bislang verfügbaren Datenlage und Messkonzepte nicht möglich. Zum einen bedarf es einer transparenten und nach sozialen Kriterien differenzierten Darstellung der Leistungsrücknahmen in der gesetzlichen Rentenversicherung. Zum anderen muss die Frage beantwortet werden, ob das Ziel der Riester-Förderung erreicht wird, nämlich die reduzierten individuellen Ansprüche aus der ersten Säule mit neu erworbenen Ansprüchen aus der zweiten und dritten Säule zu kompensieren. Der Beitrag plädiert für Wirkungs- und Verteilungsanalysen von Rentenreformen, so wie sie für Arbeitsmarktreformen selbstverständlich existieren.", "pub_time": "2012"}
{"sha256": "3646e03cba5613f7ac994bb14256792848d91c167e6e1ddcb531a18b4d0b83c2", "doi": "", "title": "Existenzgründungsförderung für Arbeitslose – Neue Ergebnisse für Deutschland ", "author": "Marco Caliendo, Viktor Steiner, Hans J.Baumgartner", "keyword": "", "abstract": "", "pub_time": "2006"}
{"sha256": "d81c754e80598434e6bfe2790688352e47a1a0ef9cf4c87eba0a4cea9ffb0032", "doi": "10.18723/diw_wb:2018-42-6", "title": "Werden die Sozialdemokraten nicht mehr gebraucht?", "author": "Alexander Kritikos", "keyword": "", "abstract": "", "pub_time": "2018"}
{"sha256": "a1dfd31eb24f3ea30df5ad3a01388287a719d3fbd00698a4dbf68dd6a54d8fab", "doi": "10.18723/diw_wb:2018-26-2", "title": "INTERVIEW MIT C. KATHARINA SPIESS „Infoworkshop bestärkt vor allem Nichtakademikerkinder in ihrer Studienabsicht“", "author": "C. Katharina Spiess", "keyword": "", "abstract": "", "pub_time": "2018"}
{"sha256": "003876c6151ac373d5fb2490be7d5f7c5227e70a508b7c0e73599f77200dde8d", "doi": "10.18723/diw_wb:2019-41-2", "title": "\"Wenn wir heute investieren, dannitte in zukunftsfähige Technologien\"", "author": "Prof Dr. Claudia Kemler", "keyword": "", "abstract": "", "pub_time": "2019"}
{"sha256": "3683ab5241ad2bec002e5d57f978571211013595712d83b862da1d72369546fe", "doi": "", "title": "Ostsee-Pipeline: Die Gewinne werden neu verteilt", "author": "Franz Hubert, Irina Suleymanova", "keyword": "", "abstract": "", "pub_time": "2009"}
{"sha256": "6c1b3dd057be8707694d0d510e9c60e61a319f12a14e12fa0bd6f9f252497a2a", "doi": "", "title": "Grundlinien der Wirtschaftsentwicklung 2006/2007", "author": "", "keyword": "", "abstract": "", "pub_time": "2006"}
{"sha256": "35b643b610c57c4dd4bed687d5a4610bc1d03e3c7067b485cc682f17bebcc122", "doi": "", "title": "IAB-BAMF-SOEP-Befragung von Geflüchteten: Überblick und erste Ergebnisse", "author": "Herbert Brücker, Nina Rother, Jürgen Schupp", "keyword": "", "abstract": "", "pub_time": "2016"}
{"sha256": "d6bd5c284dbc98b305f380abea89be6830aafbd18049f76660a641c72bfe5019", "doi": "", "title": "Wandel in der Arbeitswelt", "author": "   \nMichael Arnold, Anselm Mattes, Cert G. Wagner, Aleksandar Zalkan, Claudia Kemfert, Stefan Bach\n \n ", "keyword": "labor force participation, middle class, atypical employment, SOEP", "abstract": "Since the 1980s, in (West)Germany has been a substantial decline in the number of people of working age who are not in paid employment. Accordingly, the share of 18- to 67-year-olds without a job has also fallen. This increase in employment figures primarily benefited those in marginal employment or solo entrepreneurs and had less of an impact on those in typical employment. In fact, the present analysis, based on data from the Socio-Economic Panel (SOEP) study, shows that there has been no decline in the share of those of working age who are in typical employment. However, individuals in atypical employment are exposed to some very specific risks. There are various possible measures that may help counteract this type of employment, including abolishing the special legislation on “mini-jobs” (salary of up to 450 euros per month), expanding childcare options, and introducing mandatory retirement and accident insurance for the uninsured self-employed.", "pub_time": "2016"}
{"sha256": "d766d3677e2fba484d34fee7ef97df9dd082289d504e2781bdd436e5c9996061", "doi": "", "title": "Ein Instrument zur Messung der Preisentwicklung auf dem Wohnungsmarkt: Das Beispiel Berlin", "author": "Konstantin A. Kholodilin, Andreas Mense ", "keyword": "Home rents and prices, hedonic regression, German regions, Berlin", "abstract": "", "pub_time": "2012"}
{"sha256": "d76e3a2a79c70193237a7ec0b89389087ae40629d1e34e9a5b99c5d4f56803c4", "doi": "", "title": "Power Exchanges in the Liberalised Electricity Market", "author": "Barbara Praetorius", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "00002c1043ca350cf87e20d17bf0c0e9df6664d27eb2660b1a43c1925f406f46", "doi": "", "title": "基于 SOM 聚类的典型车况和动力匹配分析与决策", "author": "高 涛, 丁伟东, 张敏, 谭魏盟, 赵祥模", "keyword": "典型车况, 动力匹配分析, 自组织特征映射网络", "abstract": "在残酷的重型卡车市场竞争环境下，如何客观分析用户的动力配置需求，并对其进行最优配置是车企始终追求的目标。基于车速与车辆工况最强相关的观点，首先对车载数据终端所采集的样本数据进行预处理，采用自组织特征映射网络 (self-organizing feature map，SOM) 聚类分析方法进行速度分布聚类。然后针对不同类型车辆真实数据的聚类结果，总结出各 类车型的典型工况。最后结合典型工况与车辆具体配置进行动力匹配分析，从而挖掘出各类车辆的工况需求和动力配置要求。数据化的需求分析为车企在研发、生产、销售等环节消除了歧义，降低了质量投诉以及售后支出，这表明该方案在实践中有着重要的实用价值。", "pub_time": "2017"}
{"sha256": "0000328b7f7115b2a6377ca9ca837526592e99a15ea0555c5e53c0270a6cffff", "doi": "", "title": "为中国式现代化贡献中国工人力量", "author": "", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "000080b7ffcdbadb6619613d3e68379548849b8e9cac991febdac72b5ad471ec", "doi": "", "title": "扛责上肩持续发力推进党风廉政建设", "author": "段卫国", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "00008c90a4506f5a8c00dbf02635951784db83be9b0a4e1f8f45559a940d099a", "doi": "", "title": "高职高专护理专业协同育人培养模式的探索与实践", "author": "戢慧", "keyword": "医教协同,护理教育,培养模式", "abstract": "如何培养高素质技能型护理人才是专科护理教育长期研究的重要课题。本研究以楚雄医药高等专科学校护理教学改革为切入点，在深入教学医院调研基础上，指出护理协同育人应重视医教协同宣传，明确实用型护理人才培养目标，加强师资队伍建设，推进教学模式改革。", "pub_time": "2019"}
{"sha256": "0000a49d1abb1421834cddd728e4d4e8a72a7509be403f797f12efdb70560d4c", "doi": "", "title": "气相色谱法测定地表水中三溴甲烷", "author": "季向阳", "keyword": "吹扫捕集,气相色谱法,地表水,三溴甲烷", "abstract": "建立了吹扫捕集气相色谱法测定地表水中三溴甲烷的方法。该方法具有灵敏度高、检出限低、定量准确、操作简便等特点。三溴甲烷在一定浓度范围内线性关系良好，当进样量为5mL时，检出限为0.08μg/L，加标回收率在93.9%~104.5%之间，适用于地表水中三溴甲烷的测定。", "pub_time": "2016"}
{"sha256": "0000b24e111451806302e1d876a3c06698655b63ad29527b86dcdde1e098b244", "doi": "", "title": "石粉含量对再生混凝土氯离子渗透性能的影响", "author": "王磊, 张军豪, 洪陈凯, 白龙臻", "keyword": "再生混凝土,石粉,氯离子渗透,拟合公式,作用机理", "abstract": "以C60混凝土破碎、筛分成再生骨料配置C30、C40、C50混凝土为试验对象，研究机制砂石粉含量变化对再生混凝土抗氯离子渗透性能影响. 研究结果表明，C40、C50混凝土石粉含量在8%左右，C30混凝土石粉含量在 12%左右，抗氯离子渗透性能最佳，并从微观角度给出了石粉对不同强度等级再生混凝土抗氯离子渗透性能作用机理. 同时，通过对氯离子渗透系数时变规律的研究，给出了C30~C50再生混凝土氯离子渗透系数的拟合公式.", "pub_time": "2016"}
{"sha256": "0000e5ef5c24d489235d5fbba66017160bc78672e08c527d5be17590baf387dc", "doi": "", "title": "油田数字化建设存在问题与对策分析", "author": "吴迪", "keyword": "油田数字化,建设,问题,对策", "abstract": "油田的数字化建设主要是在信息技术等高科技手段的加持下，采用地理信息数据、电子地图数据以及高分辨率的地理信息卫星来实现油田的勘探、开发、运输、销售的全流程作业，实现油田日常管理的高效与科学，同时在节省大量资源与成本的同时达到最高的经济效益。我国石油储量总量比较丰富，经过一段时间以来的发展，石油勘探开采已经取得了一定的成果，然而依然还存在着许多问题， 采用数字化的管理模式能够在一定程度上解决这些油田管理的痼疾，并实现石油企业的现代化升级，从而向着更高、更远的发展目标迈进。", "pub_time": "2022"}
{"sha256": "0001ace88c32aa750633c9a85658eebaf60d3a6bf032b3585722cb3e517d6633", "doi": "", "title": "房地产企业土地增值税税收筹划相关问题及对策", "author": "黄小迪, 万伟", "keyword": "房地产企业,土地增值税,税收筹划", "abstract": "房地产行业的健康发展对我国经济健康增长有举足轻重的作用。作为开发成本的重要组成部分， 土地增值税是房地产企业税收筹划的重要对象。本文在对土地增值税的理论概述基础上，基于目前我国房地产企业土地增值税税收筹划的四条路径和三项原则，提出了企业在税收筹划过程中面临的困境，并列出应对策略，以期对房地产企业的税收筹划提供经验参考，促进行业 的持续健康发展。", "pub_time": "2023"}
{"sha256": "0001b99a9334af329a32fe765f5d693953734010d1a90c2473702a52f4ee9cad", "doi": "10.3969/j.issn.1671-332X.2016.08.019", "title": "奥美拉唑预防应激性黏膜病变的临床观察", "author": "林小玲", "keyword": "应激性,奥美拉唑,黏膜病变", "abstract": "目的 探讨分析使用奥美拉唑预防应激性黏膜病变的临床效果和药效作用机制。方法 按数字表法随机选取 2013 年 5 月－2015 年 3 月就诊并接受骨科手术患者 100 例，根据用药的不同而分成对照组和观察组各 50 例，观察组使用奥美拉唑预防应激性黏膜病变，而对照组使用雷尼替丁加以预防，统计比较两组患者预防效果。 结果 观察组患者术后黑便、出血等应激反应发生率合计为24.00% ，而对照组各术后应激反应发生率合计则为 68.00% ，观察组应激反应发生率显著较低，且组间差异在统计学上有意义( P ＜ 0. 05) ; 观察组用药后抑酸效果相对观 察者速度较慢，但是最终 pH 值差异无统计学意义( P ＞ 0.05) ; 观察组患者用药后出现恶心、皮疹等不良用药反应概率合计12.0% 低于对照组的 26. 0% ，组间差异在统计学上无意义( P ＞ 0. 05) 。结论 使用奥美拉唑预防应激性黏膜病变效果明显，奥美拉唑能够改善患者胃液 pH 值、通过抑制胃酸分泌保护黏膜细胞，明显降低患者应激性黏膜病变的发生率，用药后患者感染、黑便等各应激反应发生率明显降低，且安全可靠。", "pub_time": "2016"}
{"sha256": "0001c87b0491712a68a8edcb7104c5f70c6e293e213736bed8ed4427f7c9436b", "doi": "", "title": "移情在英语教学中的应用", "author": "李君", "keyword": "移情, 赏识, 英语教学", "abstract": "学生在教学中获得良好的情感体验，是提高其学习积极性与主动性的关键。在英语教学过程中，教师要科学运用教材的情感资源，进行移情性备课，并要以情移情，彰显教师的真爱。同时，教师要赏识学生，提高学生的自信心，让学生产生良好的情感体验，真正促进学生的学习。", "pub_time": "2015"}
{"sha256": "0001c8d98f8757e0fc6f935009dc41cc52a472ec046708859182fe8b35f0e72e", "doi": "10.13733/j.jcam.issn.2095-5553.2016.05.048", "title": "基于GSM网络和485总线的农业监控系统设计", "author": "可晓海, 张文超, 唐开辉, 路翀", "keyword": "分体式, 监控系统, GSM, 485总线, 传感器", "abstract": "针对传统农业检测仪器的不足，结合西北地区实际需求，融合仪器仪表检测技术、自动化控制技术、传感器技术、远程监控和局域网技术，采用分体式模块结构的思想，设计一种远程监控、智能调节的农业仪器监控系统来调节大棚的环境气候，确保农作物处于适宜的生长环境。", "pub_time": "2016"}
{"sha256": "0001ecbc0c5a38f1f02bb7b8b77223d0e87074ac576425224235fc4ecdf08e15", "doi": "", "title": "汉中：思想赋能，争当新时代高质量发展排头兵", "author": "苏红义", "keyword": "", "abstract": "", "pub_time": "2022"}
{"sha256": "0002052867a25505cb94854419a08f74a0a12fd224048c2d27e359aa78b34720", "doi": "", "title": "《中国药业》重返“中国科技核心期刊”", "author": "", "keyword": "", "abstract": "", "pub_time": "2017"}
{"sha256": "00020fc036fb2dfd193501fc2f32ec52737ba84f1fbf6273d512612bde992fbf", "doi": "10.3969/j.issn.1008-0287.2016.01.04", "title": "3 种复合材料的体内相容性比较", "author": "银保, 汤逊, 熊成东, 何祺, 尹劲", "keyword": "聚-D，L-乳酸, β-磷酸三钙, 可吸收材料, 组织学, 电镜", "abstract": "目的 观察 3 种可吸收柱状材料植入动物体内的组织相容性，为临床应用提供依据。方法 选择 60 只 新西兰大白兔，按随机数字表法分成 3 组，每组 20 只，雌雄各半，分别将 6% β-磷酸三钙( β-TCP) /聚-D，L-乳 酸( PDLLA) 、12% β-TCP/PDLLA 和纯 PDLLA 3 种可吸收柱状材料植入兔右侧股骨髁及臀外侧肌肉内; 左侧为对照组。术后 4、8、12、16 及 24 周取出材料进行大体观察和光镜观察。6% β-TCP/PDLLA 复合材料行植入前及术后 8、16、24 周电镜观察。结果 所有动物术后一般情况良好。术后伤口无红肿，均一期愈合，2 周内缝线自行脱落。实验周期内无感染、化脓及组织液化。24 周时 6% β-TCP/PDLLA 组柱状材料，部分被新生骨组织吸收替代，骨小梁排列较整齐，可见哈弗管及致密骨形成; 12% β-TCP/PDLLA 组柱状材料见大量新生骨组织替代，也可见致密骨形成，但其降解吸收相对较快; 纯 PDLLA 组柱状材料骨组织形成相比另 2 组成骨量较少。6% β-TCP/PDLLA 材料 24 周时电镜下材料内层水解明显，因被降解吸收，多部位出现塌陷而结构紊乱破损，内部见大量无裂隙的扭曲样改变。对照组 24 周时骨小梁进行改建，可见致密的板层骨，但仍有较多腔隙。结论 3 种可吸收柱状材料的组织相容性良好，6% β-TCP/PDLLA 材料降解过程较另 2 组材料平稳，可能是较为理想的椎体重建可吸收复合材料。", "pub_time": "2016"}
{"sha256": "35a7fd6ffa6f611ae2a2d50713ec28b82b9f7306e497599bccdee923e500358c", "doi": "10.1101/2022.01.17.476555", "title": "Capturing the signalling dynamics of the MAPK-AKT-mTOR pathway in a single targeted phosphoproteomics assay", "author": "Donna O. Debets, Juan Manuel Valverde, Maarten Altelaar", "keyword": "", "abstract": "The MAPK-AKT-mTOR protein network integrates extra- and intracellular signals to determine cellular fate, regulating pivotal biological processes such as cell growth and metabolism. Due to this crucial role, pathway dysregulation has been implicated in multiple diseases, such as metabolic disorders and cancer. The MAPK-AKT-mTOR pathway consists of dozens of proteins and signal transduction is primarily driven by protein phosphorylation. Here, we present a targeted phosphoproteomics assay to study the phosphorylation dynamics of the MAPK-AKT-mTOR pathway in detail with high sensitivity and in a high throughput manner. By using a multi-protease approach, we increased the pathway coverage with phosphosites that were previously inaccessible. This novel approach yields the most comprehensive method for the detailed study of mTOR signalling to date (covering 150 phosphopeptides on more than 70 phosphoproteins), which can be applied to in vitro and in vivo systems and has the sensitivity to be compatible with small sample amounts. We demonstrate the feasibility of this assay to monitor the plasticity of MAPK-AKT-mTOR phosphorylation dynamics in response to cellular stimuli with high temporal resolution and amino acid residue specificity. We found highly dynamic phosphorylation events upon treatment with growth factors, revealing the sequential nature of phosphosites in this signalling pathway. Furthermore, starvation of glucose and amino acids showed upregulation of AKT-targets PRAS40T246 and FOXO3T32, highlighting the role of AKT in cellular response to starvation. These findings illustrate the potential of this assay to obtain new biological insight when monitoring dynamics of functional phosphosites.", "pub_time": "2022"}
{"sha256": "35ae79ef4a928385a088eebd5a20193337f0eb4c6dd06273c80dc6e332b23a71", "doi": "10.1101/334839", "title": "Interplay between coding and exonic splicing regulatory sequences", "author": "Nicolas Controdona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvêche, Sébastien Lemaire, Léon-Charles Tranchevent, Laurent Modolo, Franck Mortreux, Cyril F. Bourgeois, Didier Auboeuf", "keyword": "", "abstract": "The inclusion of exons during the splicing process depends on the binding of splicing factors to short low-complexity regulatory sequences. The relationship between exonic splicing regulatory sequences and coding sequences is still poorly understood. We demonstrate that exons that are coregulated by any splicing factor share a similar nucleotide composition bias. We next demonstrate that coregulated exons preferentially code for amino acids with similar physicochemical properties because of the non-randomness properties of the genetic code. Indeed, amino acids sharing physicochemical properties correspond to codons that have the same nucleotide composition bias. These observations reveal an unanticipated bidirectional interplay between the physicochemical features encoded by exons and exon splicing regulation by splicing factors. We propose that the splicing regulation of an exon by a splicing factor is tightly interconnected with the physicochemical properties of the exon-encoded protein domain depending on the splicing-factor affinity for specific nucleotides.\n", "pub_time": "2018"}
{"sha256": "d6b7ceabe60552a1bb84abd05818ecbf15db98bd2a6b435131049de83bce4750", "doi": "10.1101/2021.05.07.440146", "title": "Elevated nest temperature has opposing effects on host species infested with parasitic nest flies", "author": "Lauren Albert, Samantha Rumschlag, Alexandra Parker, Grace Vaziri, Sarah A. Knutie", "keyword": "eastern bluebird, ectoparasites, host defenses, Protocalliphora sialia, 20 temperature effects, tree swallow, resistance", "abstract": "Environmental factors, such as elevated temperature, can have varying effects on hosts and their parasites, which can have consequences for disease outcomes. The individual direct effects of temperature must be disentangled to determine the net-effect in host-parasite relationships, yet few studies have determined the net-effects in a multi-host system. To address this gap, we experimentally manipulated temperature and parasite presence in the nests of two host species infested by parasitic blowflies (Protocalliphora sialia). We conducted a factorial experiment by increasing temperature (or not) and removing all parasites (or not) in the nests of eastern bluebirds (Sialia sialis) and tree swallows (Tachycineta bicolor). We then measured nestling morphometrics, blood loss, and survival and quantified parasite abundance. We predicted that if temperature had a direct effect on parasite fitness, then elevated temperature would cause similar directional effects on parasite abundance across host species. If temperature had a direct effect on hosts, and therefore an indirect effect on the parasite, parasite abundance would differ across host species. Heated swallow nests had fewer parasites compared to non-heated nests. In contrast, heated bluebird nests had more parasites compared to non-heated nests. The results of our study demonstrate that elevated temperature can have differential effects on host species, which can impact infestation susceptibility. Furthermore, changing climates could have complex net-effects on parasite fitness and host health across multi-host-parasite interactions.", "pub_time": "2022"}
{"sha256": "6b60d033c47f2cddee6d49e702aeb3ec148a09f6ec44a48f019192a3aae3d7a7", "doi": "10.1101/2020.09.01.277335", "title": "iBRAB: in silico based-designed Broad-spectrum Fab against H1N1 Influenza A Virus", "author": "Phuc-Chau Do, Trung H. Nguyen, Uyen T.M. Vo, Ly Le", "keyword": "H1N1, antigen-binding fragment, protein modeling, flexible docking", "abstract": "Influenza virus A is a significant agent involved in the outbreak of worldwide epidemics, causing millions of fatalities around the world by respiratory diseases and seasonal illness. Many projects had been conducting to investigate recovered infected patients for therapeutic vaccines that have broad-spectrum activity. With the aid of the computational approach in biology, the designation for a vaccine model is more accessible. We developed an in silico protocol called iBRAB to design a broad-reactive Fab on a wide range of influenza A virus. The Fab model was constructed based on sequences and structure of available broad-spectrum Abs or Fabs against a wide range of H1N1 influenza A virus. As a result, the proposed Fab model followed iBRAB has good binding affinity over 27 selected HA of different strains of H1 influenza A virus, including wild-type and mutated ones. The examination also took by computational tools to fasten the procedure. This protocol could be applied for a fast designed therapeutic vaccine against different types of threats.", "pub_time": "2020"}
{"sha256": "35a87ec1fda4c7290333b491c8d802c7a8336d2e0e70b6b25892a764e765e6ae", "doi": "", "title": "从《春波影》看徐士俊的戏曲观 ———兼与卓人月比较", "author": "梁雪", "keyword": "徐士俊, 《春波影》, 主情说, 卓人月, 悲怨说", "abstract": "明末清初文人徐士俊一生文学创作颇丰，诗、词、文、曲等创作成绩斐 然，特别是杂剧《春波影》问世后，产生很大反响。 《春波影》体现了徐士俊“主情说” 与“悲怨说”的戏曲观。 其“主情说” 提倡抒写真情，将摹写真情融入戏曲创作中。 “悲怨说”则是深受好友卓人月影响。 徐士俊通过作品主题、关注人物内心变化、故 事模式及故事结局，实践卓人月的“悲怨”曲论。 徐士俊与卓人月有着共同的戏曲观 念，即“主情”，徐、卓二人“悲怨”的戏曲观既存在相同之处，亦同中有异。 从《春波 影》看徐士俊的戏曲观，有利于深化对徐士俊戏曲思想的认识，对于了解明末清初文 人的戏曲思想具有重要意义。", "pub_time": "2021"}
{"sha256": "35a93ebfa02196655c70696843a633c5bd136ffc8594054a746bc8ba30dbeb9c", "doi": "", "title": "要重视计量单位的规范化教学", "author": "张善金", "keyword": "计量单位,符号,标准", "abstract": "本文依据国家技术监督局颁布的中华人民共和国国家标准，概述了我国法定计量单位构成及其同时并用、科研和生产实践中易出现的非法定计量单位进行了归纳分析，给出了规范计量单位教学的一般原则和方法。", "pub_time": "2000"}
{"sha256": "35a974af81f92c4715bd4728568e4a7a1ac17d76917648a33a31b001edfa1a20", "doi": "10.16653/j.cnki.32-1034/f.2019.018.032", "title": "基于海外技术技能人才培养的工业汉语课程标准研究", "author": "陈曼倩, 刘建国, 张向辉", "keyword": "职业教育,国际化,工业汉语,课程标准", "abstract": "文章以国际化背景下工业汉语课程标准开发为研究对象，在系统阐释课程标准制定依据和开发思路的基础上，深入分析了工业汉语系列课程标准的设计路径与创新特色，并就课程标准实施提出若干建议，以突破传统研究概念化、浅层化、片面化的局限，以促进具有国际化视野和国际化素质的高技术技能人才的培养，同时，在国际舞台上传播中国先进技术与职业教育成果，增强我国高等职业教育的国际影响力。", "pub_time": "2019"}
{"sha256": "35a97cf7c9b6f6e4981aa6836b8b2a592abf6fac52ac4c52a15a6f9874af8796", "doi": "", "title": "美丽的成熟——记中国十大女杰刘中慧", "author": "", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35a992ee7120cbf2fff7239d85a2ce0249ff0e61573e26cf4bc7951adb95e1a2", "doi": "   \n10.3969/j.1mm.2009-0126.20.01.04\n \n ", "title": "电生理指标联合应用在颅内巨大动脉瘤手术中的作用", "author": "姜燕, 许百男, 孙正辉, 姜金利, 卜博", "keyword": "颅内动脉瘤, 诱发电位, 躯体感觉, 脑电描记术, 外科手术", "abstract": "目的 研究躯体感觉诱发电位（SEP）、脑电图、脑干听觉诱发电位（BAEP）联合应用在颅内巨大动脉瘤手术治疗中的影响及临床意义。方法 分别对23例颅内巨大动脉瘤患者进行手术直接夹闭或动脉瘤孤立加旁路移植手术，同时行SEP、脑电图和BAEP实时监测，观察手术操作对其的影响。结果 23例患者行颅内巨大动脉瘤手术操作时，均不同程度引起SEP、脑电图和BAEP的变化。其中SEP的N20、P25潜伏期延长3～5 ms，波幅较术前降低50%；BAEP的Ⅰ、Ⅲ、Ⅴ波潜伏期延长0.7～1.0 ms，Ⅰ～Ⅲ、Ⅲ～Ⅴ波幅间期及Ⅰ、Ⅴ波幅电位较术前降低30%～50%以上。结论 术中动态监测SEP、脑电图和BAEP的电位变化，可以提示颈动脉阻断后的脑灌注状态，对调整手术时间及手术方式具有重要的指导意义。", "pub_time": "2010"}
{"sha256": "35a9bc99dcef0d324821c1e1b3b7080062c329d9be5e8153b8711240cdac214f", "doi": "", "title": "两类B样条模糊系统及其应用", "author": "谭彦华, 李洪兴, 许吉祥", "keyword": "B样条, 模糊系统, 逼近精度, 模糊控制, 泛逼近性", "abstract": "能够同时逼近函数及其导函数的模糊系统在应用中具有重要意义．本文利用B样条函数作为推理前件，得到了两类能够同时逼近函数及其导函数的B样条模糊系统．其中第一类B样条模糊系统是插值系统且对函数及其一阶导函数分别具有二阶和一阶逼近精度，第二类B样条模糊系统是拟插值系统且对函数及其一阶、二阶导函数均具有二阶逼近精度．最后，将这两类模糊系统应用到一级倒立摆的稳定控制中，仿真结果表明利用这两类模糊系统设计的控制器是可行的，且具有一定的鲁棒性．", "pub_time": "2011"}
{"sha256": "35ab1910767e40f505dc4f2b2b3846afe9ee1f0b2c5b6a9ac5048a1f5768a6e7", "doi": "10.3969/j.issn.1672-7193.2011.04.030", "title": "综合治疗疱疹样溃疡疗效观察 ", "author": "王雯", "keyword": "疱疹样溃疡, 综合治疗, 疗效观察", "abstract": "目的 探讨综合疗法对疱疹样溃疡的治疗作用。方法 对96例疱疹样溃疡患者用甲硝唑联合利多卡因含漱液含漱，用消毒棉签蘸云南白药粉末涂敷病损面，口服余麦口咽合剂，评价其综合治疗效果。结果 痊愈70例，治愈率73%，好转24例，好转率25%，无效2例，无效率2%，总有效率98%。结论 疱疹样溃疡为复发性口腔溃疡（RAU）中的一种，采取综合疗法治疗具有较好临床疗效，能缩短病程、有效降低复发率。", "pub_time": "2011"}
{"sha256": "35ab513fd0a9871136f9ad0afcbc7ae57c27722e6acf114dc61bf177b8f074d2", "doi": "10.3969/j.issn.1006-4931.2021.Z2.003", "title": "右美托咪定复合氟哌利多预防剖宫产术中卡前列素氨丁三醇不良反应效果观察", "author": "孙宇睿, 陈建平", "keyword": "右美托咪定, 氟哌利多, 卡前列素氨丁三醇, 剖宫产, 药品不良反应", "abstract": "目的 观察剖宫产术中右美托咪定复合小剂量氟哌利多预防卡前列素氨丁三醇不良反应的临床效果。方法 选择山西白求恩医院2018年12月至2019年6月收治的足月妊娠行择期剖宫产手术患者60例，按随机数字表法分为氟哌利多组（A组）和右美托咪定复合氟哌利多组（B 组），各 30 例。两组产妇剖宫产术中子宫体肌层注射卡前列素氨丁三醇，A 组给予氟哌利多，B 组给予氟哌利多+右美托咪定。结果 两组注射卡前列素氨丁三醇后5 min（T1 ）的血压及心率较入室静卧5 min（T0 ）显著升高，且A组显著高于B组（P < 0.05）。两组手术结束即刻（T2 ）平均动脉压及心率较T1时均显著降低，且B组显著低于A组（P < 0.05）。B组恶心呕吐及面部潮红发生率显著低于A组（P < 0.05）。结论 右美托咪定泵注复合氟哌利多能有效减少剖宫产术中应用卡前列素氨丁三醇所引起的不良反应，血流动力学相对稳定，且镇静满意，效果优于单用氟哌利多，安全性好。", "pub_time": "2021"}
{"sha256": "35acb234502259433983564adf8f51f39ac53b73b4658e90ffd053f0782f2b0a", "doi": "", "title": "针织工业 2010年第5期", "author": "陈文婷", "keyword": "", "abstract": "", "pub_time": "2010"}
{"sha256": "35b60ef0b95abe619499a2ed34dfa444d94b56a795a0723b7bf8b74b76bf8f4a", "doi": "", "title": "DEBT OVERHANG, ROLLOVER RISK, AND CORPORATE INVESTMENT: EVIDENCE FROM THE EUROPEAN CRISIS", "author": "Sebnem Kalemli-Ozcan, Luc Laeven, David Moreno", "keyword": "", "abstract": "We quantify the role of financial factors behind the sluggish post-crisis performance of European firms. We use a firm-bank-sovereign matched database to identify separate roles for firm and bank balance sheet weaknesses arising from changes in sovereign risk and aggregate demand conditions. We find that firms with higher debt levels and a higher share of short-term debt reduce their investment more after the crisis. This negative effect is stronger for firms linked to weak banks with exposures to sovereign risk, signifying increased rollover risk. These financial channels explain about 60% of the decline in aggregate corporate investment.", "pub_time": "2018"}
{"sha256": "000ea5a0acc3b4496e0fe9d876b7178ca941661604982aee8de3b94d8683b1bc", "doi": "", "title": "Commodity Price Cycles: The Perils of Mismanaging the Boom", "author": "Gustavo Adler, Sebastián Sosa", "keyword": "Commodity prices, terms of trade, economic policies", "abstract": "Commodity-exporting countries have significantly benefited from the commodity price boom of recent years. At the current juncture, however, uncertain global economic prospects have raised questions about their vulnerability to a sharp fall in commodity prices and the policies that can shield it from such a shock. To address these questions, this paper takes a long term (4 decade) view at emerging markets’ commodity dependence, the history of commodity price busts and the role of policies in mitigating or amplifying their economic impact. The paper highlights the stark difference in trends between Latin America—one of the most vulnerable regions given its high, and rising, commodity dependence—and emerging Asia—which has evolved from being a net exporter to a net importer of commodities in the last 40 years. We find evidence, however, that while commodity dependence is an important ingredient, a country’s ultimate degree of vulnerability to commodity price shocks is to a great extent determined by the flexibility and quality of its policy framework. Policies in the run-up of sharp terms-of-trade drops—especially when those are preceded by booms—play a particularly important role. Limited exchange rate flexibility, a weak external position, and loose fiscal policy tend to amplify the negative effects of these shocks on domestic output. Financial dollarization also appears to act as a shock “amplifier.”", "pub_time": "2011"}
{"sha256": "0042bf909411732ba8f22b315d8b36b3919725d7990b20b2db41dfab8a79dd04", "doi": "", "title": "农民失地及其附属权利的丧失", "author": "谭术魁", "keyword": "农民, 失地问题, 土地权利", "abstract": "农民失地问题表面上看是农民失去土地本身，其本质内容则是农民丧失多种土地附属权利。本文借助充足的数据和实例，对农民丧失土地占有使用权、承包权、收益权、经营决策权、知情参与权等附属权利作了专门剖析。", "pub_time": ""}
{"sha256": "d6c6c1e01793d608f84267d9ae0b1731a1df99f6ddab29213f17d5af63c645f8", "doi": "", "title": "Pedagogy versus School Readiness: The Impact of a Randomized Reading Instruction Intervention and Community-Based Playgroup Intervention on Early Grade Reading Outcomes in Tonga", "author": "Kevin Macdonald, Sally Brinkman, Wendy Jarvie, Myrna Machuca-Sierra, Kris McDonall, Souhila Messaoud-Galusi, Siosiana Tapueluelu and Binh Thanh Vu", "keyword": "early literacy", "abstract": "Identifying cost-effective interventions to improve early literacy is vital to developing countries, given the importance of early literacy for an individual’s future education outcomes and subsequent human capital formation. This paper presents the impact on early grade reading outcomes of two low-cost randomized interventions in Tonga: a reading instruction intervention and a community play-based activity intervention. The first intervention aims to improve early grade reading outcomes specifically; estimated impacts are approximately 0.3 standard deviation, although in some reading domains impacts are substantial, ranging from 0.6 to 0.7 standard deviation. The second intervention aims to improve school readiness and subsequently early grade reading outcomes, by providing communities with support to establish a community play-based activity. Using an instrumental variables approach, the play-based activity demonstrates positive impacts of around 0.2 standard deviation in many but not all reading domains. For the domains where a statistically significant impact is measured, the community play-based activity intervention is as at least as cost effective as the reading instruction intervention. The play-based activity intervention is shown to improve test scores by 0.21 to 0.47 standard deviation per US$100, depending on the reading test domain. The reading instruction intervention improves test scores by 0.08 to 0.34 standard deviation per US$100. These findings contribute further evidence on the effectiveness of reading instruction interventions, and possibly the first estimates of the impact of play group-type interventions on primary school reading outcomes", "pub_time": "2017"}
{"sha256": "362483694afd187ac66867b5715673cf93dc4aa9280322cef93fbd11e7b1fdb6", "doi": "", "title": "Understanding Poverty Reduction in Sri Lanka: Evidence from 2002 to 2012/13", "author": "Lidia Ceriani, Gabriela Inchauste, Sergio Olivieri", "keyword": "poverty, micro-decompositions, micro-simulations, Sri Lanka", "abstract": "This paper quantifies the contributions to poverty reduction observed in Sri Lanka between 2002 and 2012/13. The methods adopted for the analysis generate entire counterfactual distributions to account for the contributions of demographics, labor, and non-labor incomes in explaining poverty reduction. The findings show that the most important contributor to poverty reduction was growth in labor income, stemming from an increase in the returns to salaried nonfarm workers and higher returns to self-employed farm workers. Although some of this increase in earnings may point to improvements in productivity, defined as higher units of output per worker, some of it may simply reflect increases in food and commodity prices, which have increased the marginal revenue product of labor. To the extent that there have been no increases in the volumes being produced, the observed changes in poverty are vulnerable to reversals if commodity prices were to decline significantly. Finally, although private transfers (domestic and foreign) helped to reduce poverty over the period, public transfers were not as effective. In particular, the reduction in the real value of transfers of the Samurdhi program during 2002 to 2012/13 slowed down poverty reduction.", "pub_time": "2015"}
{"sha256": "3640b2f135b5a511192ab81b23e4a683608999c6ff02ae0116a3a92c9fe17bd5", "doi": "", "title": "A manual for the identification and removal of administrative barriers to investment Module 1: About the manual: the cycle of reform", "author": "", "keyword": "", "abstract": "", "pub_time": "2006"}
{"sha256": "a173a0e87155bf60291269d0fdde027c6342a53fdf363c178247f45a9b7cae75", "doi": "", "title": "LESSONS FROM THE FAMILY PLANNING EXPERIENCE FOR COMMUNITY-BASED ENVIRONMENTAL EDUCATION", "author": "Winifred Weekes-Vagliani", "keyword": "", "abstract": "This paper starts out reviewing and comparing the World Population Plan of Action and the UNESCO-UNEP Global Strategy for Environmental Education: the objectives, tactics, actors and institutions. Subsequently, the examination of numerous materials from the family planning field provides some examples to be emulated by community-based environmental activities in developing countries. Population, cultural and gender variables are also sought in some existing environmental education and protection efforts. It is hoped that such information will increase the ability to integrate these concerns into environmental education and public awareness programmes. The analysis builds on the author's previous research on gender issues.\n", "pub_time": "1992"}
{"sha256": "6c2815804dc93136a5d4849ca808f4480849dcdea8fecc4162adefc97b8bd804", "doi": "10.1787/f0394ef5-en", "title": "ORGANISED DECENTRALISATION OF COLLECTIVE BARGAINING – CASE STUDIES OF GERMANY, NETHERLANDS AND DENMARK", "author": "Christian Lyhne Ibsen, Maarten Keune", "keyword": "", "abstract": "This paper investigates different varieties of so called organised decentralisation of collective bargaining in Germany, the Netherlands and Denmark. Organised decentralisation occurs within the framework of sector agreements, which explicitly allow determination of terms and conditions at company level, and often set certain (minimum) level standards as well as procedure that have to be respected. German decentralisation is based on its dual-channel system and extensive use of opening clauses, which make workplace derogation from sector-level agreements possible. Dutch decentralisation is based on the dual-channel system and on framework agreements that allow company level bargaining as long as minimum stipulations are observed. Finally, Denmark combines a single-channel system with framework agreements setting minimum levels. Germany stands out as the least organised of the three. Opening and derogation clauses mean that terms and conditions in multi-employer agreements can be undercut. Vertical control over these derogations has suffered from the dual-channel representation in which works councils have a new role. The Netherlands exhibit some, very limited, elements of disorganisation and stable bargaining coverage. Decentralisation has mainly happened through framework agreements setting minimum levels or through the organised transfer of competencies to works councils. The Danish system leaves a lot of scope for local bargaining, the minimum levels are generally observed and bargaining coverage has not suffered. Based on these findings, we draw the conclusion that organised decentralisation requires articulation that preserves a regulatory function of multi-employer agreements. Preservation of multi-employer agreements in turn requires high bargaining coverage. ", "pub_time": "2018"}
{"sha256": "d743a3570277744f057fdaa9728af7d783b3ffa364a1ac58447e0bae6818d7f0", "doi": "10.1787/5jlv81sclr35-en", "title": "Cross-Country Comparison of Farm Size Distribution", "author": "Raushan Bokusheva, Shingo Kimura ", "keyword": "Agriculture, farm size distribution, structural change", "abstract": "This report summarises selected measures of the farm size distribution for fourteen OECD countries: Canada, Estonia, France, Germany, Ireland, Italy, Japan, Korea, Latvia, the Netherlands, Norway, Sweden, the United Kingdom (England) and the United States over the period 1995-2010. The farm size statistics are presented for four major production systems: crop, dairy, cattle and pig farming. The report documents consolidation of agricultural production in large-scale farms in most countries and sub-sectors covered by the report. Nevertheless, farm size growth rates show substantial differences across countries and periods which underlines the importance of country-specific natural, social, and economic conditions and the regulatory and policy environment for the evolution of farm structures. Increased inequality in farm size distributions, as captured using Gini coefficients, indicates a trend towards more polarized farm structures.", "pub_time": "2016"}
{"sha256": "a0f8a90372032623eaabc140edb77b46b16c2d0f1a36628a057bcbd5981addee", "doi": "", "title": "Optimal predictiOn pools", "author": "John Geweke, Gianni Amisano", "keyword": "forecasting, GARCH, log scoring, Markov mixture, model combination, S&P 500 returns, stochastic volatility", "abstract": "A prediction model is any statement of a probability distribution for an outcome not yet observed. This study considers the properties of weighted linear combinations of n prediction models, or linear pools, evaluated using the conventional log predictive scoring rule. The log score is a concave function of the weights and, in general, an optimal linear combination will include several models with positive weights despite the fact that exactly one model has limiting posterior probability one. The paper derives several interesting formal results: for example, a prediction model with positive weight in a pool may have zero weight if some other models are deleted from that pool. The results are illustrated using S&P 500 returns with prediction models from the ARCH, stochastic volatility and Markov mixture families. In this example models that are clearly inferior by the usual scoring criteria have positive weights in optimal linear pools, and these pools substantially outperform their best components.", "pub_time": "2009"}
{"sha256": "35a579175d6d3a951cc4bf57bdc7c4cb38c5b0dfa750cca630c5d03488c00cde", "doi": "10.1530/EDM-17-0173", "title": "Hepatotoxicity in hyperthyroid patient after consecutive methimazole and propylthiouracil therapies", "author": "Fernando Gomez-Peralta, Pablo Velasco-Martínez, Cristina Abreu, María Cepeda and Marta Fernández-Puente", "keyword": "", "abstract": "Methimazole (MMI) and propylthiouracil (PTU) are widely used antithyroid drugs (ATD) that have been approved for the treatment of hyperthyroidism. Hepatotoxicity may be induced by these drugs, though they exert dissimilar incidence rates of hepatotoxicity and, possibly, with different underlying pathogenic mechanisms. We report the case of a 55-year-old woman with no relevant medical history diagnosed with hyperthyroidism due to Graves’ disease, who developed two episodes of acute hepatitis concurrent with the consecutive administration of two different ATDs, first MMI and then PTU. Given the impossibility of administering ATDs, it was decided to perform a total thyroidectomy because the patient was found to be euthyroid at that point. Pathological anatomy showed diffuse hyperplasia and a papillary thyroid microcarcinoma of 2mm in diameter. Subsequent clinical check-ups were normal. This case suggests the importance of regular monitoring of liver function for hyperthyroid patients. Due to the potential severity of this side effect, it is recommended to determine baseline liver function prior to initiation of treatment.", "pub_time": "2018"}
{"sha256": "35a916f3f3d7576d16e0699fe212814daf1ab84e6f4945340d74f3de757ec4a5", "doi": "10.3389/fcvm.2021.723542", "title": "Doppler Echocardiography Assessment of Coronary Microvascular Function in Patients With Angina and No Obstructive Coronary Artery Disease", "author": "Jakob Schroder, Eva Prescott", "keyword": "coronary flow velocity reserve, stress echocardiography, coronary microvascular dysfunction, prognosis, sex", "abstract": "Echocardiographic evaluation is an essential part of the diagnostic work-up in patients with known or suspected cardiovascular disease. Transthoracic Doppler echocardiography (TTDE) enables straightforward and reliable visualization of flow in the left anterior descending artery. In the absence of obstructive coronary artery disease, low TTDE-derived coronary flow velocity reserve (CFVR) is considered a marker of coronary microvascular dysfunction (CMD). TTDE CFVR is free from ionizing radiation and widely available, utilizing high-frequency transducers, pharmacologic vasodilator stress, and pulsed-wave Doppler quantification of diastolic peak flow velocities. European Society of Cardiology guidelines recommend TTDE CFVR evaluation only following preceding anatomic invasive or non-invasive coronary imaging excluding obstructive CAD. Accordingly, clinical use of TTDE CFVR is limited and CMD frequently goes undiagnosed. An evolving body of evidence underlines that low CFVR is an important and robust predictor of adverse prognosis and continuing symptoms in angina patients both with and without obstructive CAD. The majority of angina patients have no obstructive CAD, particularly among women. This has led to the suggestion that there may be a gender-specific female atherosclerotic phenotype with less epicardial obstruction, and a low CFVR signifying CMD instead. Nevertheless, available evidence indicates low CFVR is an equally important prognostic marker in both men and women. In this review, TTDE CFVR was evaluated regarding indication, practical and technical aspects, and interpretation of results. Association with symptoms and prognosis, comparison with alternative invasive and non-invasive imaging modalities, and possible interventions in angina patients with low CFVR were discussed, and key research questions were proposed.", "pub_time": "2021"}
{"sha256": "35afacce2c7225a1c9616c92603ebb6831fa154c362d84a83f411281037c59c4", "doi": "10.1093/jas/sky387", "title": "Effects of pyrroloquinoline quinone supplementation on growth performance and small intestine characteristics in weaned pigs", "author": "Xindi Yin, Dongxu Ming, Lili Bai, Fei Wu, Hu Liu, Yifan Chen, Linlin Sun, Yidong Wan, Philip Alfred Thacker, Guoyao Wu", "keyword": "", "abstract": "This study was conducted to explore the effect of graded levels of pyrroloquinoline quinone disodium (PQQ·Na₂) on the performance and intestinal development of weaned pigs. A total of 216 pigs weaned at 28 d were assigned in a randomized complete block design to 6 diets containing 0, 1.5, 3.0, 4.5, 6.0, or 7.5 mg/kg PQQ·Na₂ for 28 d. Performance, diarrhea incidence, intestinal morphology, redox status, cytokines, and the expression of tight junction proteins were determined. Pig had increased ADG (linear, P < 0.01), GF (quadratic, P < 0.01), and lower diarrhea incidence (P < 0.01) with the increase of PQQ·Na₂ supplementation. Villus height increased (quadratic, P < 0.01) in all segments of the small intestine, and crypt depth in the duodenum and jejunum was decreased (linear, P < 0.05) in pigs with the increase of PQQ·Na₂ supplementation. Pigs fed PQQ·Na₂-supplemented diets had higher (P < 0.05) activities of antioxidant enzymes including total superoxide dismutase in duodenum, jejunum, and ileum; glutathione peroxidase (GSH-Px) in jejunum and ileum; catalase (CAT) in duodenum and ileum; and lower (P < 0.05) malondialdehyde concentrations in the intestinal mucosa of all segments. In the intestinal mucosa, cytokines including interleukin (IL)-1β, IL-2, and interferon-γ were significantly decreased (P < 0.05) in pigs fed PQQ·Na₂-supplemented diets. The protein expression of zonula occludens protein-1 (ZO-1) and occludin in jejunum was significantly increased (P < 0.05) in pigs fed diets containing PQQ·Na₂. In conclusion, these results have indicated that dietary PQQ·Na₂ supplementation improves growth performance and gut health in weaned pigs. Moreover, pigs fed diet with as low as 1.5-mg/kg PQQ·Na₂ have better performance compared with pigs fed no PQQ·Na₂-supplemented diet; pigs fed diet with 4.5-mg/kg PQQ·Na₂ have highest GF among treatments during the whole period.", "pub_time": "2018"}
{"sha256": "35b0b98fc6a93e0530c05b3cb805eb111d6ccfe39385dfab7b4adeb686425475", "doi": "", "title": "An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual", "author": "S. Pawaria, K.L. Moody, P. Busto, K. Nündel, R. Baum, S. Sharma, E.M. Gravallese, K.A. Fitzgerald, A. Marshak-Rothstein", "keyword": "TLR7, TLR9, DNaseII, arthritis, autoantibody, anti-nuclear antibody, splenomegaly, extramedullary haematopoiesis, STING, bifunctional antibody", "abstract": "Objective. The goal of this study was to determine whether endosomal Tolllike receptors (TLRs) contribute to the clinical manifestation of systemic autoimmunity exhibited by mice that lack the lysosomal nuclease DNaseII.\nMethods. DNaseII/IFNaR double deficient mice were intercrossed with Unc93b13d/3d mice to generate DNaseII-/- mice with non-functional endosomal TLRs. The resulting triple deficient mice were evaluated for arthritis, autoantibody production, splenomegaly, and extramedullary haematopoiesis. B cells from both strains were evaluated for their capacity to respond to endogenous DNA by using small oligonucleotide based TLR9 ligands and a novel class of bifunctional anti-DNA antibodies.\nResults. Mice that fail to express DNaseII, IFNaR, and Unc93b1 still develop arthritis but do not make autoantibodies, develop splenomegaly, or exhibit extramedullary haematopoiesis. DNaseII-/- IFNaR-/- B cells can respond to synthetic ODNs, but not to endogenous dsDNA.\nConclusion. RNA-reactive TLRs, presumably TLR7, are required for autoantibody production, splenomegaly, and extramedullary haematopoiesis in the DNaseII-/- model of systemic autoimmunity.", "pub_time": "2015"}
{"sha256": "35b5f4df7fdf5343d82f31ddc6f18606466918fdc8efd37c618f3a1e807e5617", "doi": "10.1186/s40359-022-00822-8", "title": "Processes of change, pros, cons, and self‑efficacy as variables associated with stage transitions for effective stress management over a month: a longitudinal study", "author": "Ke Deng, Akira Tsuda, Satoshi Horiuchi, Shuntaro Aoki", "keyword": "", "abstract": "Background: The transtheoretical model of intentional health behavior change categorizes people into experiencing five stages in understanding the process of initiating and maintaining effective stress management (i.e., engagement in any form of healthy activity that is practiced for at least 20 min per day). The first purpose of this study was to observe whether any cases would disclose stage misclassification over one month. The second was to examine whether different model’s variables are associated with the stage transitions for effective stress management at different stages.\nMethods: Data from 946 Chinese students and workers were subjected to analyses. This study is a part of a larger, longitudinal web-based study in which three surveys were conducted in March, April, and September 2014. This study analyzes the data of demographic variables, perceived stress, stages of change, processes of change, pros, cons, and self-efficacy at the point of the first survey and stages of change at the point of the second survey.\nResults: Of 144 participants who progressed from the pre-Action stages to the post-Action stages, 44 then progressed to Maintenance (practicing effective stress management for six months or longer). These patterns could not technically occur, and thus, these participants were excluded from the following analyses. Data from the remaining 902 participants were subject to a series of logistic regression analyses. Generally, the model’s variables failed to predict the stage transitions. Exceptions were found that higher experiential processes (the cognitive activities required to progress through stages) and lower self-efficacy (the confidence that one can engage in effective stress management despite barriers to it) predicted the forward and backward stage transitions from Precontemplation (with no intention to initiate effective stress management in the next six months) and Action/Maintenance (practicing effective stress management).\nConclusions: Evidence of stage misclassification indicated the limitations of the model’s stage classification. Experiential processes and self-efficacy as predictors at different stages were in line with the model’s assumption that different variables are assumed to be predictors of stage transitions at different stages, partially supporting the utility of the stage classification.", "pub_time": "2022"}
{"sha256": "35b975df0dd815723f97ba3ac960882593a42b5869d497462ed211024bec90d4", "doi": "10.1177/2397847317707370", "title": "An integrated approach to the safety assessment of food additives in early life", "author": "Anne Constable, Brinda Mahadevan, Peter Pressman, Jossie A Garthoff, Leo Meunier, Dieter Schrenk, Gerrit Speijers, Aaron O’Sullivan, and A Wallace Hayes", "keyword": "Infant formula, food additives, early life, juvenile toxicity, safety assessments", "abstract": "During the development of international standards by the Codex Alimentarius Commission, infant foods and their constituent ingredients are subject to rigorous risk analysis and are strictly regulated by many authorities. Various jurisdictions have approved only a limited number of additives specifically with regard to infant foods to fulfill specific technical requirements of quality. As part of the approval process, a rigorous safety assessment is essential to confirm that the use of additives does not pose any health risk for the consumer. An acceptable daily intake (ADI) may be derived from the toxicological databases. However, the ADI may not be applicable to infants because of the possible developmental sensitivities and potentially high exposure scenarios, leading to possible lower margins of safety than would often be determined for adult populations. There is interest in defining better food safety assessment approaches for pre-weaned infants aged less than 12–16 weeks. To confirm safe use in infants, we reviewed the suitability of the existing safety databases of six additives with historical uses in infant nutrition products. To determine further toxicity testing strategies, it is necessary to understand whether the chemical used in the additives is identical to endogenous physiological metabolites and/or whether immature organs of infants are targets of toxicity. Combined with an in-depth review of the existing relevant toxicological and nutritional studies, this integrated approach will facilitate decision-making. We propose a decision tree as a tool within this approach to help guide appropriate data requirements and identify data gaps. In cases of reasonable uncertainty, studies of targeted juvenile should be considered to investigate the safe use levels in food products.", "pub_time": "2017"}
{"sha256": "35aa993a0423c2a2927b11662123c2c528757fc2ef3005968f240cb2959cbea6", "doi": "10.3389/fpsyt.2024.1345447", "title": "Augmentative and alternative communication in autism spectrum disorder: transitioning from letter board to iPad – a case study", "author": "Dionisia Mavritsakis", "keyword": "autism spectrum disorder (ASD), communication and language, augmentative and alternative communication (AAC), cognitive abilities, apraxia", "abstract": "This case study examines the effective use of Augmentative and Alternative Communication (AAC) tools in enhancing communication skills in a 15-year-old male with Autism Spectrum Disorder (ASD). Initially exhibiting non-verbal tendencies, the subject experienced significant improvements in communication and social interaction following the introduction of a letter board and subsequent transition to an iPad. These AAC tools facilitated a marked development in his ability to articulate thoughts, engage in academic activities, and express complex ideas, particularly in science. The study highlights the role of AAC in expanding the communicative capabilities of individuals with limited or no verbal language, demonstrating notable advancements in both verbal expression and cognitive engagement. The findings underscore the transformative impact of personalized AAC interventions and suggest the potential for broader application in ASD support strategies. This case highlights the need for further research, including randomized controlled trials, to explore the efficacy of AAC tools in diverse ASD contexts.", "pub_time": "2024"}
{"sha256": "35b2a1dd7467d4bbdd73c00952e17141d7504f2abe816d9de3b9ef7eb17a7534", "doi": "10.3389/fenrg.2023.1253206", "title": "Data-driven methods for situation awareness and operational adjustment of sustainable energy integration into power systems", "author": "Shi Jin, Qian Liu, Wenlu Zhang, Zhihong He, Yuxiong He, Lihong Zhang, Yuan Liu, Peidong Xu, Xiao Zhang, Yuhong He", "keyword": "power system, situation awareness, operational adjustment, forecasting, reinforcement learning", "abstract": "In the context of increasing complexity in power system operations due to the integration of renewable energy sources, two main challenges arise: accurate short-term wind power forecasting and power flow convergence control. Accurate wind power forecasting plays a crucial role in power system scheduling, while controlling power flow convergence is essential for system stability. This study proposes a concise short-term wind power generation prediction model that combines a feature selection-based convolutional neural network-bidirectional long short-term memory network (CNN-BiLSTM) model. By effectively screening multidimensional feature datasets, the model optimizes the selection of highly correlated feature parameters and assigns weights to input data based on feature correlation. The CNN-BiLSTM combination model is then employed to establish a predictive model for wind power generation based on multiple features. Additionally, this study introduces an automatic adjustment model for power flow convergence using the D3QN (Double Dueling Q Network) reinforcement learning algorithm. This addresses the challenge of power imbalance leading to flow non-convergence, enabling effective control of power flow convergence and adaptive adjustment of operating modes. Experiments conducted using the KDD Cup 2022 wind power prediction dataset validate the wind power prediction method. The results demonstrate that the CNN-BiLSTM model effectively utilizes time-series data, surpassing other neural networks in prediction accuracy. Simulation results based on the PYPOWER case39 standard case reveal that the reinforcement learning model’s reward value increases with training rounds and stabilizes at 40. Remarkably, more than 72% of abnormal flow samples achieve rapid convergence within 10 steps, affirming the proposed method's efficacy and computational efficiency. The findings of this study contribute to enhancing the accurate awareness of new energy integration into power systems and provide a novel adaptive control method for power flow.", "pub_time": "2023"}
{"sha256": "000970f77e09d326dbe0ac7ed63b13449aa335df105bb94b877b293fe29b322b", "doi": "10.3389/fimmu.2022.839197", "title": "Predicting diagnostic gene expression profiles associated with immune infiltration in patients with lupus nephritis", "author": "Lin Wang, Zhihua Yang, Hangxing Yu, Wei Lin, Ruoxi Wu, Hongtao Yang and Kang Yang", "keyword": "lupus nephritis, immune infiltration, comprehensive bioinformatics, biomarkers, CIBERSORT", "abstract": "Objective: To identify potential diagnostic markers of lupus nephritis (LN) based on bioinformatics and machine learning and to explore the significance of immune cell infiltration in this pathology.\nMethods: Seven LN gene expression datasets were downloaded from the GEO database, and the larger sample size was used as the training group to obtain differential genes (DEGs) between LN and healthy controls, and to perform gene function, disease ontology (DO), and gene set enrichment analyses (GSEA). Two machine learning algorithms, least absolute shrinkage and selection operator (LASSO) and support vector machine-recursive feature elimination (SVM-RFE), were applied to identify candidate biomarkers. The diagnostic value of LN diagnostic gene biomarkers was further evaluated in the area under the ROC curve observed in the validation dataset. CIBERSORT was used to analyze 22 immune cell fractions from LN patients and to analyze their correlation with diagnostic markers.\nResults: Thirty and twenty-one DEGs were screened in kidney tissue and peripheral blood, respectively. Both of which covered macrophages and interferons. The disease enrichment analysis of DEGs in kidney tissues showed that they were mainly involved in immune and renal diseases, and in peripheral blood it was mainly enriched in cardiovascular system, bone marrow, and oral cavity. The machine learning algorithm combined with external dataset validation revealed that C1QA(AUC = 0.741), C1QB(AUC = 0.758), MX1(AUC = 0.865), RORC(AUC = 0.911), CD177(AUC = 0.855), DEFA4(AUC= 0.843)and HERC5(AUC = 0.880) had high diagnostic value and could be used as diagnostic biomarkers of LN. Compared to controls, pathways such as cell adhesion molecule cam, and systemic lupus erythematosus were activated in kidney tissues; cell cycle, cytoplasmic DNA sensing pathways, NOD-like receptor signaling pathways, proteasome, and RIG-1-like receptors were activated in peripheral blood. Immune cell infiltration analysis showed that diagnostic markers in kidney tissue were associated with T cells CD8 and Dendritic cells resting, and in blood were associated with T cells CD4 memory resting, suggesting that CD4 T cells, CD8 T cells and dendritic cells are closely related to the development and progression of LN.\nConclusion: C1QA, C1QB, MX1, RORC, CD177, DEFA4 and HERC5 could be used as new candidate molecular markers for LN. It may provide new insights into the diagnosis and molecular treatment of LN in the future.", "pub_time": "2022"}
{"sha256": "a0e7d2624676c4aed6ecd38dc30c71d6388149be0f169b425a595ccfcc1e3fe9", "doi": "10.3389/fcvm.2024.1287852", "title": "Research progress of drug eluting balloon in arterial circulatory system", "author": "Keji Lu, Xianglin Ye, Yaoxuan Chen, Peng Wang, Meiting Gong, Bing Xuan, Zhaobing Tang, Meiling Li, Jun Hou, Ke Peng and Haifeng Pei", "keyword": "drug eluting balloon, arterial circulatory system diseases, coronary artery diseases, instent restenosis, paclitaxel", "abstract": "The arterial circulatory system diseases are common in clinical practice, and their treatment options have been of great interest due to their high morbidity and mortality. Drug-eluting balloons, as a new type of endovascular interventional treatment option, can avoid the long-term implantation of metal stents and is a new type of angioplasty without stents, so drug-eluting balloons have better therapeutic effects in some arterial circulatory diseases and have been initially used in clinical practice. In this review, we first describe the development, process, and mechanism of drug-eluting balloons. Then we summarize the current studies on the application of drug-eluting balloons in coronary artery lesions, in-stent restenosis, and peripheral vascular disease. As well as the technical difficulties and complications in the application of drug-eluting balloons and possible management options, in order to provide ideas and help for future in-depth studies and provide new strategies for the treatment of more arterial system diseases.", "pub_time": "2024"}
{"sha256": "35a271eee862b04a65686814e681004d44e6b5f79ff7eae0712562fdd081b902", "doi": "", "title": "利用重要节日培养中职学生核心素养研究", "author": "柏桧", "keyword": "", "abstract": "重要节日作为文化传承的载体，对于中职学生的成长具有重要意义。本文从核心素养的概念出发，探讨了重要节日与培养中职学生核心素养的关系，包括传统节日对于文化素养的培养、现代节日对于 全球视野的拓展、节日庆祝活动对于社交能力的锻炼和节日心理对于情感素养的培养等多个方面。", "pub_time": "2022"}
{"sha256": "35a293d73183717e4b499654c50c3816aecb0c7a3f7f78e219d689bd452a9019", "doi": "", "title": "淮安水利发展现状分析及发展对策思考", "author": "尤其中", "keyword": "", "abstract": "", "pub_time": "2016"}
{"sha256": "35a2c62c79b7cdc54e87f84e804c942be711f093eb43b2ae34d75519c5afb215", "doi": "", "title": "事业单位党建工作质量:问题与对策", "author": "李红, 赵国付", "keyword": "事业单位, 党建工作, 信用记录", "abstract": "事业单位党建工作发展现状中存在学习内容缺乏吸引力、政策保障不足、入党标准良莠不齐、理论学习时间仓促等问题，从提升队伍素质水平、加强政治学习效果与宣传效果的角度出发，应丰富宣传载体，注重学习内容设计，增加信用记录为入党门槛条件，加大政治理论学习深度，突出党建文化宣传引导，从而提高事业单位党建工作质量。", "pub_time": "2017"}
{"sha256": "35a2d3ec147454c159c84c79d2410a92762baa1a7d99fe0f6cf87b341f2a651c", "doi": "", "title": "上海轻工—沃尔玛 零距离接触", "author": "东桥, 山水", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "35a2e28e4065892be1ea368ba66716580bb64d6dd8cd34e9b2c42d59a6cc0da7", "doi": "", "title": "透视房地产开发融资渠道的变化", "author": "李楠, 赵财福", "keyword": "", "abstract": "房地产开发是典型的投资额大、投资回收期长的资金密集型行业，资金是制约行业发展的瓶颈，如何有效融资一直是房地产开发商最关心的问题。\n目前对于我国的房地产开发企业来说，商业银行贷款仍然是最主要的融资渠道，具体表现有：凭借开发商的资信获取的贷款、开发商以自己的房地产或其他资产作抵押或质押担保获取的贷款、由第三者提供担保的贷款等。在90年代初期，银行较为宽松的融资贷款环境，促进了房地产行业的迅猛发展，但同时也使银行承担了巨大的贷款风险，因房地产开发过热，银行出现了大量坏帐。经过几年的低潮期，房地产行业从去年开始叉表现出了强劲的上升势头，房地产业被定位为国民经济新的增长点和支柱产业，而房地产开发企业进入资本市场的禁令解除、房地产投资基金从理论探讨到实际操作以及中国加入世贸组织都为房地产开发融资提供了全新的渠道，这些扩展的融资渠道将有力地推动房地产市场的发展，对未来的房地产行业具有重要影响。", "pub_time": "2002"}
{"sha256": "35a2ec5671a328986f1108e7a6d11bfeef79770937c10b5ced39182d75dbf0fe", "doi": "", "title": "“低筋小麦粉 + 白灵菇”无糖营养饼干的工艺优化及消化特性研究", "author": "陈旭斌, 陈培泓", "keyword": "无糖营养饼干, 工艺优化, 消化特性", "abstract": "本研究以黑龙江新良粮油集团有限公司的低筋小麦粉为基础材料，结合福建武夷山夷达菇业有限公司的白灵菇粉，通过正交试验设计和单因素试验，优化了无糖营养饼干的工艺配方。最终确定的最佳工艺条件为白灵菇粉 10%、木糖醇 25%、食盐 0.5%、油脂 30%、泡打粉 3%。通过验证试验，表明该配方在感官评分和剪切力方面表现出较高的稳定性和可重复性。", "pub_time": "2024"}
{"sha256": "35a312b562f8055b4af4fd954b8696f80f5fcdc079bd4d0f582813a314ae7b4d", "doi": "", "title": "万般滋味，都是生活", "author": "", "keyword": "", "abstract": "", "pub_time": "2019"}
{"sha256": "35a31d93289da9d6d88165cf0dcb2052b1d534b8876c2aac2b67cebb12780f27", "doi": "", "title": "388例宫颈上皮内瘤样病变筛查结果分析", "author": "白合尼莎, 房新志, 迪丽努尔", "keyword": "", "abstract": "近年随着宫颈细胞学采用描述性诊断(TBS)的应用，临床上结合阴道镜及活检检查提高了对宫颈病变，特别是对官颈早期癌及癌前病变的诊断率达到了早期诊断、早期治疗的目的现总结对新疆肿瘤医院388例宫颈细胞学涂片异常的患者阴道镜下检查及多点活检，作组织病理学检查，结果作对照研究。 ", "pub_time": "2007"}
{"sha256": "35a3791780dd942ffaa47b4e9fdbaf5d3f9c2f5015309543a9b28a03af0cabd1", "doi": "", "title": "为测试工具选择正确的保险丝", "author": " 美国福禄克公司", "keyword": "", "abstract": "本文介绍了在使用那些内部未设计有保险丝保护功能的测试仪进行电压和电流测量时的潜在危险 , 这些危险会造成严重的烧伤，甚至可能会导致生命危险 。", "pub_time": "2005"}
{"sha256": "35a3d4d275b2e509d5778ad3b662ea7b96655b429a15689cfc2e02de2993ff53", "doi": "", "title": "智能压力变送器多种应用方式的探讨", "author": "刘洋, 孙克梅", "keyword": "压力, 变送器, 测量方式", "abstract": "压力、差压变送器是过程变量变送器中最重要的一类，随着生产过程自动化程度的不断提高，在生产过程控制领域得到越来越广泛的应用，除了可用于压力、差压测量之外，还可用于流量、液位、比重等其他参数测量，以差压原理的流量测量技术更是在流量测量领域占有绝对的高的比例。差压变送器在各种应用领域中的安装及设置方法也多种多样，针对其在这些测量领域的测量方法及原理进行分类的阐述。\n", "pub_time": "2006"}
{"sha256": "35a3ea5f6563545b5651bd6443255a51e5727ab02986ac934c99472838fd8b93", "doi": "", "title": "浅议手术室安全护理及术前健康教育的重要性", "author": "王安先, 李方燕", "keyword": "", "abstract": "近年来我院对手术室护理工作进行了改革，重视了术前对手术病人的健康教育和术后的随访工作，形成了以病人为中心，以工作为轴心，满足了护患需求，并逐步完善术中护理质量，使护理工作有了新的起色和进步，受到了病人的好评，也得到了护理人员的认可，现结合实践对我院术中安全护理的点滴体会浅议如下。", "pub_time": "2004"}
{"sha256": "359a8ba67ad5cfd29e1ab96f67bd5b13c26f016c110bcb57baaadedb440327a0", "doi": "", "title": "Indirect illusory inferences from disjunction: a new bridge between deductive inference and representativeness ", "author": "Mathias Sablé-Meyer, Salvador Mascarenhas", "keyword": "", "abstract": "We provide a new link between deductive and probabilistic reasoning fallacies. Illusory inferences from disjunction are a broad class of deductive fallacies traditionally explained by recourse to a matching procedure that looks for content overlap between premises. In two behavioral experiments, we show that this phenomenon is instead sensitive to real-world causal dependencies and not to exact content overlap. A group of participants rated the strength of the causal dependence between pairs of sentences. This measure proved to be a near perfect predictor of fallacious reasoning by an independent group of participants in illusory inference tasks with the same materials. In light of these results, we argue that all extant accounts of these deductive fallacies require non-trivial adjustments. Crucially, these novel indirect illusory inferences from disjunction bear a structural similarity to seemingly unrelated probabilistic reasoning problems, in particular the conjunction fallacy from the heuristics and biases literature. This structural connection was entirely obscure in previous work on these deductive problems, due to the theoretical and empirical focus on content overlap. We argue that this structural parallelism provides arguments against the need for rich descriptions and individuating information in the conjunction fallacy, and we outline a unified theory of deductive illusory inferences from disjunction and the conjunction fallacy, in terms of Bayesian confirmation theory.", "pub_time": "2021"}
{"sha256": "d6d2ba3c8733823b77a162e645174c493dc73b17e7f65c121926ea9e0933c879", "doi": "", "title": "Study protocol: Social Health Impact of Network Effects (SHINE) Study", "author": "Danielle Cosme, Yoona Kang, José Carreras-Tartak, Jeesung Ahn, Faustine Corbani, Nicole Cooper, Bruce P. Doré, Xiaosong He, Chelsea Helion, Mia Jovanova, Silicia Lomax, Arun S. Mahadevan, Amanda L. McGowan, Alexandra M. Paul, Rui Pei, Anthony Resnick, Ovidia Stanoi, Tianyun (Sky) Zhang, Yi Zhang, Dani S. Bassett, Zachary M. Boyd, David M. Lydon-Staley, Peter J. Mucha, Kevin N. Ochsner, Emily B. Falk\n", "keyword": "mindfulness, perspective-taking, social influence, intervention, longitudinal data ", "abstract": "Humans are a fundamentally social species whose well-being depends on how we connect with and relate to one another. As such, scientific understanding of factors that promote health and well-being requires insight into causal factors present at multiple levels of analysis, ranging from brain networks that dynamically reconfigure across situations to social networks that allow behaviors to spread from person to person. The Social Health Impacts of Network Effects (SHINE) study takes a multilevel approach to investigate how interactions between the mind, brain, and community give rise to well-being. The SHINE protocol assesses multiple health and psychological variables, with particular emphasis on alcohol use, how alcohol-related behavior can be modified via self-regulation, and how thoughts, feelings, and behaviors unfold in the context of social networks. An overarching aim is to derive generalizable principles about relationships that promote well-being by applying multilayer mathematical models and explanatory approaches such as network control theory. The SHINE study includes data from 711 college students recruited from social groups at two universities in the northeastern United States of America, prior to and during the COVID-19 pandemic. Participants completed at least one of the following study components: baseline self-reported questionnaires and social network characterization, self-regulation intervention assignment (mindful attention or perspective taking), functional and structural neuroimaging, ecological momentary assessment, and longitudinal follow-ups including questionnaires and social network characterization. The SHINE dataset enables integration across modalities, levels of analysis, and timescales to understand young adults’ well-being and health-related decision making. Our goal is to further our understanding of how individuals can change their thoughts, feelings, and behaviors, and of how these changes unfold in the context of social networks.", "pub_time": ""}
{"sha256": "a14107ce9dfaed7ce1a00f07e1eed94fb517c55f52117b716bec766298378788", "doi": "", "title": "Temporal change in pronoun use and its application to cultural psychology: the case of the Russian language in the 20th century", "author": "Borysenko L. H.", "keyword": "", "abstract": "", "pub_time": "2017"}
{"sha256": "003d8fa991e02c989edfe487b3294c0bb76a4c6236843026cae176666dff8598", "doi": "", "title": "From distal to proximal to interactive: Behavioral and brain synchrony during attraction, courtship, and sexual interaction ", "author": "James G. Pfaus, Ellen Zakreski, Adam Safron", "keyword": "", "abstract": "We tend move in time and space in what feels like a synchronous flow. Flow appears as movement along a steady and continuous stream, and is determined by external contingencies or operants, Pavlovian associations among stimuli, and a set of internal neural mechanisms that make the required movements appear fluid, goal directed, and meaningful. Some movements are relatively hardwired, such as those required to suckle a breast for food or to scratch an itch. Others are formed as motor habits, such as those required to ride a bike or drive a car, and become automated and hardwired with practice. Some movements become self-synchronized and coordinated with other movements, for example, body and limb movements with the production of phonemes and meaningful speech (e.g., Condon, 1977; 1979; Fentress, 1984). Such movements become gestures that convey emphasis and emotional meaning.", "pub_time": ""}
{"sha256": "0047dbfd74cca63d44f9ca070abd5ca17337a06d771288ee73fad8c5a39a6cad", "doi": "", "title": "Harmless bodily pleasures are moralized because they are perceived as reducing self-control and cooperativeness", "author": "Léo Fitouchi, Jean-Baptiste André, Nicolas Baumard & Daniel Nettle\n", "keyword": "morality; cooperation; self-control; values; social cognition; evolutionary psychology", "abstract": "Why do many people moralize harmless bodily pleasures, such as gluttony, masturbation, and drinking alcohol? In three pre-registered experiments (N > 1,600), we investigated whether this is because they perceive bodily pleasures as indirectly facilitating antisocial behaviors by altering self-control. In Study 1 and 2, participants judged that targets who increased (vs. decreased) their indulgence harmless sex, food, alcohol, and laziness had become less cooperative, an effect mediated by the perception that they had become less self-controlled. In Study 3, participants judged that relaxing regulations over sex, food, and alcohol in a village would decrease self-control and cooperation in the village, although they judged enforcing puritanical prohibitions even more negatively. In all studies, the perception that indulgence reduces self-control and cooperativeness predicted the moral condemnation of harmless bodily pleasures. This supports the idea that some purity violations, although apparently harmless, are moralized because they are perceived as indirectly affecting cooperation. ", "pub_time": ""}
{"sha256": "6c31593349c21838257d442af1cfa2d334d0a0d8d12865c140581377e7c42cec", "doi": "10.1007/978-3-319-97529-0_7", "title": "Technology Habits: Progress, Problems, and Prospects", "author": "Joseph B. Bayer, Robert LaRose", "keyword": "Internet, Online, Smartphone, Digital, Addiction, Components, Cues, Contexts", "abstract": "Technology habits have been objects of research for over 100 years and provided heuristic cases for the study of habits over the last two decades. This chapter traces the history of research on information and communication technologies in daily life, with an eye toward measurement and conceptualization problems. Similar to the new technologies of earlier eras, the prominence of current habitual manifestations has raised challenging questions for both researchers and societies. These new-er media habits may exaggerate core habitual mechanisms by providing a wide spectrum of potential cues, possible contexts, and complex rewards—resulting in dynamic habits that appear to be “special”. We discuss how research on technology habits serves to uncover the assumptions, boundaries, and moderators of habit, while calling for a revised approach to address recurring problems in the literature. Altogether, the chapter clarifies how technology habit research contributes to a broader understanding of habitual behaviour.", "pub_time": "2018"}
{"sha256": "0054a5ff1a20400f992d2d2f1a4bf084601c109cd9e174c53ea2583a757d8be2", "doi": "", "title": "GROUPS 4 HEALTH versus Cognitive Behaviour Therapy in young people with depression and loneliness: A randomized, Phase 3, non-inferiority trial with 12-month", "author": "Tegan Cruwys, Catherine Haslam, Joanne A Rathbone, Elyse Williams, S Alexander Haslam, Zoe C Walter\n", "keyword": "loneliness, group psychotherapy, mood disorders, depression, mental health, adolescence, youth, social isolation, social identity", "abstract": "Background. Depression treatments are typically less effective for young people than for adults. However, extant treatments rarely target loneliness, which is a key risk factor in the onset, maintenance, and development of depression.\nAims. This study evaluated the efficacy of a novel loneliness intervention, GROUPS 4 HEALTH (G4H), relative to best-practice treatment Cognitive Behaviour Therapy (CBT) in reducing loneliness and depression over a 12 month period.\nMethods. The study was a Phase 3, randomised non-inferiority trial comparing G4H to dose-controlled group CBT. Participants were 174 young people aged 15-25 years experiencing loneliness and clinically significant symptoms of depression, who were not in receipt of adjunct treatment. Participants were recruited from mental health services in Southeast Queensland, Australia. Randomisation was conducted using computer software. Follow-up assessments and statistical analyses were blind to allocation. Both interventions consisted of 5 x 75 min group-based psychotherapy sessions. The primary outcomes were depression and loneliness, with a non-inferiority margin of 2.20 for depression. The trial was prospectively registered on the Australian New Zealand Clinical Trial Registry (ACTRN12618000440224) on 27 March 2018 and is closed to new participants.\nResults. 174 participants were enrolled between 24 April 2018 and 25 May 2019, with 84 in the G4H condition and 90 in the CBT condition. All randomised participants were included in the intention-to-treat analyses (N=174). The pre-post effect sizes for depression were d=- .71G4H and d=-.91CBT. For loneliness, they were d=-1.07G4H and d=-0.89CBT. At 12-month follow-up, the absolute difference between groups in depression was 1.176 (95%CI: -1.94, 4.29), and in loneliness was -0.679 (95%CI: -.1.43, .07). No adverse effects were observed.\nConclusions. G4H was non-inferior to CBT for depression and showed a slight advantage over CBT for loneliness that emerged after treatment completion.", "pub_time": "2021"}
{"sha256": "a0ef1ea55027ff422585792f3a3d81e40b209340ba604e757b787a6305fc5249", "doi": "", "title": "Benefits of Adaptive Learning Transfer from Typing-Based Learning to Speech-Based Learning", "author": "Thomas Wilschut, Florian Sense, Maarten van der Velde, Zafeirios Fountas, Sarah C. Maaß, Hedderik van Rijn", "keyword": "adaptive learning, memory, pronunciation, speech, vocabulary learning, reaction times, ACT-R", "abstract": "Memorizing vocabulary has led to an important aspect of formal foreign-language learning. Advances in cognitive psychology have led to the development of adaptive learning systems that make vocabulary learning more efficient. One way these computer-based systems optimize learning is by measuring learning performance in real time to create optimal repetition schedules for individual learners. While adaptive learning systems have been successfully applied to word learning using keyboard-based input, they have thus far seen little application in spoken word learning. Here we present a system for adaptive, speech-based word learning using an adaptive model that was developed for and tested with typing-based word learning. We show that typing- and speech-based learning result in similar behavioral patterns that can be used to reliably estimate individual memory processes, and we extend earlier findings demonstrating that a response-time based adaptive learning system outperforms an accuracy-based, Leitner flashcard learning algorithm. In short, we show that adaptive learning benefits transfer from typing-based learning, to speech based learning. Our work provides a basis for the development of language learning applications that use real-time pronunciation assessment software to score the accuracy of the learner's pronunciations. The development of adaptive, speech-based learning applications is important for two reasons. First, by focusing on speech, the model can be applied for individuals whose typing skills are insufficient—as is demonstrated by the successful application of the model in an elderly participant population. Second, speech-based learning models are educationally relevant because they focus on what may be the most important aspect of language learning: to practice speech.", "pub_time": ""}
{"sha256": "d7992a7164c16a3d94819bb19f747a9897f81da381d4e1375fc45c4ace78d9c0", "doi": "", "title": "Elevated moral condemnation of third-party violations in multiple sclerosis patients", "author": "Indrajeet Patil, Liane Young, Vladimiro Sinay, Ezequiel Gleichgerrcht", "keyword": "morality, punishment, alexithymia, multiple sclerosis , moral luck", "abstract": "Recent research has demonstrated impairments in social cognition associated with multiple sclerosis (MS). The present work asks whether these impairments are associated with atypical moral judgment. Specifically, we assessed whether MS patients are able to integrate information about intentions and outcomes for moral judgment (i.e., appropriateness and punishment judgments) in the case of third-party acts. We found a complex pattern of moral judgments in MS patients: although their moral judgments were comparable to controls’ for specific types of acts (e.g., accidental or intentional harms), they nevertheless judged behaviors to be less appropriate and endorsed more severe punishment across the board, and they were also more likely to report that others’ responses would be congruent with theirs. Further analyses suggested that elevated levels of externally oriented cognition in MS (due to co-occurring alexithymia) explain these effects. Additionally, we found that the distinction between appropriateness and punishment judgments, whereby harmful outcomes influence punishment judgments to a greater extent than appropriateness judgments, was preserved in MS despite the observed disruptions in affective and motivational components of empathy. The current results inform the two-process model for intent-based moral judgments as well as possible strategies for improving the quality of life in MS patients. ", "pub_time": ""}
{"sha256": "6b460b676793f9db0cc7ea5326c217e73cfe5797794e769b301a5cd7dd649d3d", "doi": "10.1016/j.jde.2005.02.003", "title": "Periodic solutions of perturbed isochronous hamiltonian systems at resonance", "author": "Christian Fabry, Alessandro Fonda", "keyword": "Periodic solution, Hamiltonian systems, opological degree", "abstract": "We look for periodic solutions of planar systems obtained by adding an asymptotically positively homogeneous nonlinear term to an isochronous hamiltonian system. Precise computations of the topological degree are obtained by elementary phase-plane analysis.", "pub_time": "2005"}
{"sha256": "6b4a869978df928bca8170387d9bcb97bf19704c00062afd12d4d70a259f4601", "doi": "10.1002/mame.200800158", "title": "Influence of Clay Modification on the Properties of Resol Nanocomposites", "author": "Liliana B. Manfredi, Debora Puglia, Annalisa Tomasucci, José M. Kenny, Analia Vázquez", "keyword": "", "abstract": "Two organically modified (Cloisite1 30B and 10A) and one unmodified clay (Cloisite1 Na) were added to a resol-type phenolic prepolymer. The modified montmorillonites showed a better dispersion in the prepolymer. The dispersion of the clay, the chemical structure as well as the thermal degradation behavior of the cured polymer and nanocomposites were studied. It was observed that the addition of Cloisite1 Na leads to enhanced crosslinking of the cured polymer, leading to a higher activation energy for thermal degradation. The resol with Cloisite1 10A contained a higher percentage of voids, which seems to be one of the major factors that reduce hardness and adhesive strength when the nanocomposite was applied to a metal substrate.", "pub_time": "2008"}
{"sha256": "6b4d9f7bbd9f1cf70527a58fb2286496053fcbe6a59acf47493715d89426a479", "doi": "10.7202/700803ar", "title": "Bérenger, Jean, L’Europe danubienne de 1848 à nos jours, Paris, Presses Universitaires de France, 268 p.", "author": " Stanislav Kirschbaum", "keyword": "", "abstract": "", "pub_time": "1977"}
{"sha256": "6b549aa7fee31e99f175c3dba8d74bcc733d09562a4432f6986c666ab76f8481", "doi": "", "title": "The ‘molten globule’ state is involved in the translocation of proteins across membranes?", "author": "Valentina E. Bychkova, Roger H. Pain, Oleg B. Ptitsyn", "keyword": "   \nProtein folding, Molten globule state, Protein translocation, Membrane translation, Deraturation\n \n ", "abstract": "Strong evidence exists that the translocation of proteins across a variety of membranes involves a non-native or denatured conformational state. On the other hand a compact state having secondary but not rigid tertiary structure and called the 'molten globule' state has been identified as being stable under mild denaturing conditions. A similar state has been shown to accumulate on the folding pathway of globular proteins. These states are compact though sufficiently expanded to include water, and they are internally mobile. It is proposed that these molten globule states may be suitable candidates for protein translocation across biological membranes.", "pub_time": "1988"}
{"sha256": "6b5a6e6e6287b59762b5a23c71c06e33e8a7f448d83facdc756976fa2b5efe0a", "doi": "10.7202/012955ar", "title": "Précis de Literal Meaning", "author": "François Recanati", "keyword": "", "abstract": "", "pub_time": "2006"}
{"sha256": "6b5b786495548ea2844e665eeed4b421f4163354e027f077102a626fc004ee3c", "doi": "10.1163/15685373-13010034", "title": "Neither Fish nor Fowl. How EU Delegations Challenge the Institution of Diplomacy: The Cases of Moscow and Washington", "author": "Heidi Maurer, Kristi Raik", "keyword": "diplomacy, EU foreign policy, EU delegations, United States, Russia", "abstract": "The paper explores European diplomatic cooperation abroad since 2009 by studying the diplomatic structures and practices in two key locations, Moscow and Washington. It analyses the functions of EU delegations as part of the hybrid EU foreign policy system and their way of engaging with the changing global patterns of diplomatic practice. The empirical analysis draws on extensive semi-structured interviews conducted in Moscow and Washington in 2013/14. Our cases confirm the deeper institutionalisation and intensification of European diplomatic cooperation abroad. The EU delegations increasingly took over traditional diplomatic tasks and coordinated member states on the ground. The ability of the EU delegations to establish a good working relationship with member states as well as the leadership of key individuals (notably EU ambassadors) were key factors in shaping the way this new system fell into place, which shows the continued prevalence of hybridity in EU foreign policy making.", "pub_time": "2018"}
{"sha256": "a0e5097f71dc20bf104aca528601fe2bae2d0b39bfdea78b332201b301ca7b3f", "doi": "10.1088/1755-1315/50/1/012035", "title": "A Method of Effective Quarry Water Purifying Using Artificial Filtering Arrays", "author": "M Tyulenev, E Garina, A Khoreshok, O Litvin, Y Litvin, E Maliukhina", "keyword": "", "abstract": "The development of open pit mining in the large coal basins of Russia and other countries increases their negative impact on the environment. Along with the damage of land and air pollution by dust and combustion gases of blasting, coal pits have a significant negative impact on water resources. Polluted quarry water worsens the ecological situation on a much larger area than covered by air pollution and land damage. This significantly worsens the conditions of people living in cities and towns located near the coal pits, and complicates the subsequent restoration of the environment, irreversibly destroying the nature. Therefore, the research of quarry wastewater purifying is becoming an important mater for scholars of technical colleges and universities in the regions with developing open-pit mining. This paper describes the method of determining the basic parameters of the artificial filtering arrays formed on coal pits of Kuzbass (Western Siberia, Russia), and gives recommendations on its application. ", "pub_time": "2017"}
{"sha256": "a0e56c2c81258083a05534eeabefb9084c2c51f87b02bd160b3f1f122349ef22", "doi": "10.3390/pr7020086", "title": "Life Cycle Assessment and Economic Analysis of an Innovative Biogas Membrane Reformer for Hydrogen Production", "author": "Gioele Di Marcoberardino, Xun Liao, Arnaud Dauriat, Marco Binotti, Giampaolo Manzolini", "keyword": "biogas, hydrogen production, fluidized bed membrane reactor, life cycle assessment, economic analysis\n", "abstract": "This work investigates the environmental and economic performances of a membrane reactor for hydrogen production from raw biogas. Potential benefits of the innovative technology are compared against reference hydrogen production processes based on steam (or autothermal) reforming, water gas shift reactors and a pressure swing adsorption unit. Both biogas produced by landfill and anaerobic digestion are considered to evaluate the impact of biogas composition. Starting from the thermodynamic results, the environmental analysis is carried out using environmental Life cycle assessment (LCA). Results show that the adoption of the membrane reactor increases the system efficiency by more than 20 percentage points with respect to the reference cases. LCA analysis shows that the innovative BIONICO system performs better than reference systems when biogas becomes a limiting factor for hydrogen production to satisfy market demand, as a higher biogas conversion efficiency can potentially substitute more hydrogen produced by fossil fuels (natural gas). However, when biogas is not a limiting factor for hydrogen production, the innovative system can perform either similar or worse than reference systems, as in this case impacts are largely dominated by grid electric energy demand and component use rather than conversion efficiency. Focusing on the economic results, hydrogen production cost shows lower value with respect to the reference cases (4 €/kgH2 vs 4.2 €/kgH2) at the same hydrogen delivery pressure of 20 bar. Between landfill and anaerobic digestion cases, the latter has the lower costs as a consequence of the higher methane content.", "pub_time": "2019"}
{"sha256": "35a853cfcb053c01c71ced2a2ae1f405fbd566a1e291969024fddb432a16258b", "doi": "10.1371/journal.pone.0093190", "title": "Small Theropod Teeth from the Late Cretaceous of the San Juan Basin, Northwestern New Mexico and Their Implications for Understanding Latest Cretaceous Dinosaur Evolution", "author": "Thomas E. Williamson, Stephen L. Brusatte", "keyword": "", "abstract": "Studying the evolution and biogeographic distribution of dinosaurs during the latest Cretaceous is critical for better understanding the end-Cretaceous extinction event that killed off all non-avian dinosaurs. Western North America contains among the best records of Late Cretaceous terrestrial vertebrates in the world, but is biased against small-bodied dinosaurs. Isolated teeth are the primary evidence for understanding the diversity and evolution of small-bodied theropod dinosaurs during the Late Cretaceous, but few such specimens have been well documented from outside of the northern Rockies, making it difficult to assess Late Cretaceous dinosaur diversity and biogeographic patterns. We describe small theropod teeth from the San Juan Basin of northwestern New Mexico. These specimens were collected from strata spanning Santonian – Maastrichtian. We grouped isolated theropod teeth into several morphotypes, which we assigned to higher-level theropod clades based on possession of phylogenetic synapomorphies. We then used principal components analysis and discriminant function analyses to gauge whether the San Juan Basin teeth overlap with, or are quantitatively distinct from, similar tooth morphotypes from other geographic areas. The San Juan Basin contains a diverse record of small theropods. Late Campanian assemblages differ from approximately co-eval assemblages of the northern Rockies in being less diverse with only rare representatives of troodontids and a Dromaeosaurus-like taxon. We also provide evidence that erect and recurved morphs of a Richardoestesia-like taxon represent a single heterodont species. A late Maastrichtian assemblage is dominated by a distinct troodontid. The differences between northern and southern faunas based on isolated theropod teeth provide evidence for provinciality in the late Campanian and the late Maastrichtian of North America. However, there is no indication that major components of small-bodied theropod diversity were lost during the Maastrichtian in New Mexico. The same pattern seen in northern faunas, which may provide evidence for an abrupt dinosaur extinction.", "pub_time": "2014"}
{"sha256": "35aba079efe1a1012cbee15dcda0bc32cbaaac6349840496c2ffa554e1637b64", "doi": "10.1002/hyp.6586", "title": "Composite suspended sediment particles in river systems: their incidence, dynamics and physical characteristics", "author": "J. C. Woodward, D. E. Walling", "keyword": "suspended sediment, composite particles, aggregation, flocculation, particle size, water elutriation, time-integrated sampling", "abstract": "Most of the existing data on the effective particle size characteristics of fluvial suspended sediment derive from instantaneous sampling methods that may not be representative of the overall suspended sediment loads. This presents difficulties when there is a need to incorporate effective particle size data into numerical models of floodplain sedimentation and sediment-associated contaminant transfer. We have used a field-based water elutriation apparatus (WEA) to assemble a large (36 flood) database on the time-integrated nature of the effective and absolute particle size characteristics of suspended sediment in four subcatchments of the River Exe basin of southwest England. These catchments encompass a wide range of terrains and fluvial environments that are broadly representative of much of the UK and temperate, low relief northwest Europe. The WEA provides important data on the physical characteristics of composite particles that are not attainable using other methods. This dataset has allowed, for the first time, detailed interbasin comparisons of the time-integrated particle size characteristics of suspended sediment and reliable estimates of the contribution of five effective size classes to the mean annual suspended sediment load of the study catchments. The suspended sediment load of each river is dominated by composite rather than primary particles, with, for example, almost 60% (by mass) of the sediment load of the River Exe at Thorverton transported as composite particles >16 µm in size. All the effective size classes contain significant clay components. A key outcome of this study is the recognition that each catchment has a distinctive time-integrated effective particle size signature. In addition, the time-integrated effective particle size characteristics of the suspended loads in each of the catchments display much greater spatial variability than the equivalent absolute particle size distributions. This indicates that the processes producing composite particles vary significantly between these catchments, and this has important implications for our understanding of the dynamics of suspended sediment properties.", "pub_time": "2006"}
{"sha256": "35ad8623ca20cda6b564f478904a1cb465345dbe9f064c999bfb6494d3040ae7", "doi": "10.1007/978-3-642-14282-6_23", "title": "Addressing the Privacy Paradox by Expanded Privacy Awareness - The Example of Context-Aware Services", "author": "André Deuker ", "keyword": "Privacy Paradox, Privacy Awareness, Economics of Privacy, Context-Aware Services ", "abstract": "When interacting with applications, users are less restrictive in disclosing their personal data than if asked in an application-independent context. On a more general level this behavior is termed as privacy paradox. The creation of privacy awareness can assist users in dealing with context-aware services without harming their privacy unintentionally, thereby addressing the privacy paradox. The paper in hand provides a research approach towards the integration of privacy awareness on an application-specific level, especially taking into account conflicting interests between users and providers of context-aware services. It shows that expanding privacy awareness towards knowledge about methods and tools to react turns out to be useful. ", "pub_time": "2009"}
{"sha256": "35b3bd73ac379a008e28c3edb5d598ffeef75b01577303c4b6cd2ce1e9e1965e", "doi": "", "title": "Oxidation and Volatilization from Tungsten Brush High Heat Flux Armor During High Temperature Steam Exposure", "author": "G. R. Smolik, R. J. Pawelko, R. A. Anderl, D. A. Petti", "keyword": "", "abstract": "Tungsten brush accommodates thermal stresses and high heat flux in fusion reactor components such as plasma facing surfaces or armor. However, inherently higher surface areas are introduced with the brush design. We have tested a specific design of tungsten brush in steam between 500 and 1100ºC. Hydrogen generation and tungsten volatilization rates were determined to address fusion safety issues. The brush prepared from 3.2-mm diameter welding rods had a packing density of 85 percent. We found that both hydrogen generation and tungsten volatilization from brush, fixtured to represent a unit within a larger component, were less than projections based upon the total integrated surface area (TSA). Steam access and the escape of hydrogen and volatile oxide from void spaces within the brush are restricted compared to specimens with more direct diffusion pathways to the test environment. Hydrogen generation rates from restrained specimens based on normal surface area (NSA) remain about five times higher than rates based on total surface areas from specimens with direct steam access. Volatilization rates from restrained specimens based upon normal surface area (NSA) were only 50 percent higher than our historic cumulative maximum flux plot (CMFP) for tungsten. This study has shown that hydrogen generation and tungsten volatilization from brush do not scale according to predictions with previously determined rates, but in fact, with higher packing density could approach those from flat surfaces. ", "pub_time": "2000"}
{"sha256": "a0f7ac7d6e7d81998754ef16358889a4c4e12aa90fb172db8ca0563d47db4830", "doi": "", "title": "Subcontracting and the Size and Composition of the Informal Sector: Evidence from Indian Manufacturing", "author": "Ana I. Moreno-Monroy, Janneke Pieters, Abdul A. Erumban", "keyword": "informal sector, formal sector, subcontracting, manufacturing, India", "abstract": "This paper analyzes the relationship between formal sector subcontracting and the evolution of the informal sector using nationally representative survey data of Indian manufacturing enterprises for the period 1995-2006. In these years of fast economic growth, subcontracting by formal enterprises gained importance, while the informal sector continued to account for 90 per cent of total manufacturing employment. In order to contrast between a ‘modernization’ and a ‘stagnation’ view on formal-informal production linkages, we test whether subcontracting is related to the size of more modern versus more traditional segments of the informal sector. The results show that formal sector subcontracting is positively related to the size of the informal sector only for the most modern informal activities, supporting the view that subcontracting is related to informal sector modernization. We find no support for the claim that the continued expansion of very traditional informal activities is related to increased outsourcing by formal manufacturing enterprises.", "pub_time": "2012"}
{"sha256": "3639591577f478947975e4f95dcabd079491829a598251308a23d74fbf3b60c9", "doi": "", "title": "Lost in Transition: The Influence of Locus of Control on Delaying Educational Decisions", "author": "Katharina Jaik, Stefan C. Wolter", "keyword": "locus of control, school-to-school transition, school-to-work transition", "abstract": "The transition from compulsory schooling to upper-secondary education is a crucial and frequently difficult step in the educational career of young people. In this study, we analyze the impact of one non-cognitive skill, locus of control, on the intention and the decision to delay the transition into post-compulsory education in Switzerland. We find that locus of control, measured at ages 13–14, has a significant impact on the intention to delay the transition into upper-secondary education. Furthermore, we find that the intention to delay the transition is strongly correlated with the actual delay, measured one and a half years after the intention. Finally, students with the initial intention to delay but successfully continuing into upper-secondary education show a stronger internal locus of control than comparable students who do delay their transition. ", "pub_time": "2016"}
{"sha256": "363a124d249ad8e55a09446602196946ef919c010f6addcd03b8e07ae310ed95", "doi": "", "title": "Gender Diversity, Labour in the Boardroom and Gender Quotas", "author": "Astrid Kunze Katrin, Scharfenkamp", "keyword": "affirmative action, employee representation, shared governance, co-determination, women, boards of directors, firm size", "abstract": "This study investigates boards of (non-executive) directors and whether employee representation has a positive effect on gender diversity on boards. We exploit rich, newly assembled board–director matched panel data for Norway and Germany, which contain unique information on whether a director represents shareholders or employees during the period around 2008, when a Norwegian board gender quota came into effect. We present two novel results that challenge previous thinking about the effects of board gender quotas on women directors. First, we find a positive impact of employee representation before the gender quota reform on gender diversity. Second, although the Norwegian gender quota has increased the probability of a director being female, the effect through employee representation has relatively decreased after the implementation of the reform. We discuss potential mechanisms and implications for the design of co-determination laws and gender quotas.", "pub_time": "2022"}
{"sha256": "00537e12ea0a2949786aad7dda202568d4574a0ca34c0b3a7e829ea92d5ad29a", "doi": "", "title": "Demand for Redistribution, Support for the Welfare State, and Party Identification in Austria", "author": "Andreas Kuhn ", "keyword": "subjective inequality measures, demand for redistribution, support for the welfare state, party identification", "abstract": "This paper describes subjective wage inequality and the demand for redistribution in Austria using individuals' estimates of occupational wages from the International Social Survey Program. Although these estimates differ widely across individuals, the data clearly show that most individuals would like to decrease wage inequality, relative to the level of inequality which they perceive to exist. The empirical analysis also shows that the demand for redistribution is strongly associated not only with variables describing self-interested motives for redistribution, but also with perceptions of and social norms with respect to inequality. Further, the demand for redistribution is a strong predictor for whether an individual is supportive of redistribution by the state. On the other hand, however, I find almost no evidence for an empirical association between the demand for redistribution and individuals' party identification.", "pub_time": "2009"}
{"sha256": "d873766e8c0d4a61e649e2cfbdddadd25f965b8b2f39b563c94dfeb2888b018c", "doi": "", "title": "Recession Experiences during Early Adulthood Shape Prosocial Attitudes Later in Life", "author": "Jan Bietenbeck, Uwe Sunde, Petra Thiemann", "keyword": "prosocial attitudes, impressionable years, experience effects, cohort effects", "abstract": "This paper explores whether the experience of a severe recession during early adulthood shapes individuals’ prosocial attitudes. The analysis uses survey responses to experimentally validated questions that measure prosocial attitudes for approximately 65,000 respondents in 75 countries. The identification approach exploits variation in recession experiences across 78 different birth cohorts. We find that exposure to a recession during early adulthood is associated with lower levels of prosociality later in life. The effect only emerges for experiences during impressionable years (age 18–25), mainly affects prosocial attitudes among men, and is orthogonal to the effect of experiences with democracy.", "pub_time": "2023"}
{"sha256": "35fd3be6fa401ac50ba415e31be981d36c061074e6a7e421b0587e06b26d6511", "doi": "", "title": "Firms, Industries, and Unemployment Insurance: An Analysis Using Employer-Employee Data", "author": "Miles Corak, Wen-Hao Chen", "keyword": "unemployment insurance, payroll taxes", "abstract": "Administrative data on the universe of employees, firms, and unemployment insurance (UI) recipients in Canada over an 11 year period are used to examine the operation of UI using the firm as the unit of analysis. Persistent transfers through UI are present at both industry and firm levels, and an analysis using firm fixed effect indicates that an important fraction of variation in them can be attributed to firm effects. Calculations of overall efficiency loss are very sensitive to the degree to which firm level information is used. A full appreciation of how UI interacts with the labour market requires recognition of the characteristics and human resource practices of firms.", "pub_time": "2003"}
{"sha256": "015ccb2d2dfd3062673fc954058504b5838e09473105339ced378ed12c2e028e", "doi": "", "title": "The Effectiveness of Health Screening", "author": "Franz Hackl, Martin Halla, Michael Hummer, Gerald J. Pruckner", "keyword": "health screening, health care costs, sick leave, mortality", "abstract": "Using a matched insurant-general practitioner panel data set, we estimated the effect of a general health-screening program on individuals’ health status and health care cost. To account for selection into treatment, we used regional variations in the intensity of exposure to supply-determined screening recommendations as an instrumental variable. We found that screening participation substantially increased inpatient and outpatient health care costs for up to two years after treatment. In the medium term, we found cost savings in the outpatient sector, whereas in the long run, no statistically significant effects of screening on either health care cost component could be discerned. In summary, screening participation increases health care costs. Since we did not find any statistically significant effect of screening participation on insurants’ health status at any point in time, we do not recommend a general health-screening program. However, given that we found some evidence for cost-saving potentials for the sub-sample of younger insurants, we suggest more targeted screening programs.", "pub_time": "2012"}
{"sha256": "6bac03efa2b7fdfa17f5a8f2585b92bc25004de93ffae2241da6ad5b94493c39", "doi": "", "title": "Inference with Imperfect Randomization: The Case of the Perry Preschool Program", "author": "James Heckman, Rodrigo Pinto, Azeem M. Shaikh, Adam Yavitz", "keyword": "multiple testing, multiple outcomes, randomized trial, randomization tests, imperfect randomization, Perry Preschool Program, program evaluation, familywise error rate, exact inference, partial identification", "abstract": "This paper considers the problem of making inferences about the effects of a program on multiple outcomes when the assignment of treatment status is imperfectly randomized. By imperfect randomization we mean that treatment status is reassigned after an initial randomization on the basis of characteristics that may be observed or unobserved by the analyst. We develop a partial identification approach to this problem that makes use of information limiting the extent to which randomization is imperfect to show that it is still possible to make nontrivial inferences about the effects of the program in such settings. We consider a family of null hypotheses in which each null hypothesis specifies that the program has no effect on one of several outcomes of interest. Under weak assumptions, we construct a procedure for testing this family of null hypotheses in a way that controls the familywise error rate – the probability of even one false rejection – infinite samples. We develop our methodology in the context of a reanalysis of the HighScope Perry Preschool program. We find statistically significant effects of the program on a number of different outcomes of interest, including outcomes related to criminal activity for males and females, even after accounting for the imperfectness of the randomization and the multiplicity of null hypotheses. ", "pub_time": "2011"}
{"sha256": "01c2e78a96a2b1a6cd1aedc48ec1566087f0733999e51d96a8cb4be185b2a331", "doi": "", "title": "Downward Nominal Wage Rigidity in Services: Direct Evidence from a Firm Survey", "author": "Daniel Radowski, Holger Bonin", "keyword": "nominal wage rigidity, efficiency wages, manufacturing, services, Germany", "abstract": "The paper uses a new German employer survey on wage setting practices to analyze incidence and sources of nominal wage rigidity in services vs. manufacturing. We observe that wage freezes are significantly more frequent and wage cuts less frequent in services. Reasons preventing wage cuts reported by employers suggest that fear of excess worker turnover could explain this distinct behavior. ", "pub_time": "2009"}
{"sha256": "a124b99a0e3eb27bbbfb75fee6434d1210ac04d877474c8f7c01ea0f8b1bed7d", "doi": "", "title": "Family Ceremonies as a Constraint on Informal Sector Investment: The Case of Sénégal", "author": "John Bennett, Stephanie Levy", "keyword": "informality, investment behaviour, family ceremonies", "abstract": "We analyze how intermittent large expenditures on family ceremonies may affect an entrepreneur’s investment decision in an informal enterprise. Our hypothesis is that the barrier between family and enterprise is thin and permeable. We test this hypothesis using a survey from Sénégal that combines informal sector and household data. We estimate a measure of exposure to spending on births, weddings and funerals, and show this has a significant negative relationship with the decision to invest and the amount of investment. These results are robust to changes in specifications of the determinants of investment, controlling for both enterprise- and family-related variables.", "pub_time": "2018"}
{"sha256": "a12f1b08aad1d6005c7d3abedf5f468ea62d14f872362d0c906d8faa99daaa93", "doi": "", "title": "Disability in the Welfare State: An Unemployment Problem in Disguise?", "author": "Bernt Bratsberg, Elisabeth Fevang, Knut Røed", "keyword": "disability, displacement, social insurance, employment opportunities", "abstract": "Economies with low unemployment often have high disability rates. In Norway, the permanent disability insurance rolls outnumber registered unemployment by four to one. Based on administrative register data matched with firms’ financial statements and closure data collected from bankruptcy proceedings, we show that a large fraction of Norwegian disability insurance claims can be directly attributed to job displacement and other adverse shocks to employment opportunities. For men, we estimate that job loss more than doubles the risk of entry to permanent disability and that displacements account for fully 28 percent of all new disability insurance claims. We conclude that unemployment and disability insurance are close substitutes.", "pub_time": "2010"}
{"sha256": "3632dcedebc8aae62fec749bc68be9d6579a523fb9c4b7bb6823dc8f60998fda", "doi": "", "title": "Innovation, Employment and Skills in Advanced and Developing Countries: A Survey of the Literature", "author": "Marco Vivarelli ", "keyword": "technology, innovation, employment, skill, skill-biased technological change", "abstract": "This paper critically discusses the theoretical and empirical literature on the quantitative and qualitative employment impact of technological change, compares the relative explanatory power of the competing theories, and explains in detail the macro and micro evidence on the issue, with reference both to the advanced economies and the developing countries (DCs). ", "pub_time": "2012"}
{"sha256": "365337e65895d0d229e91aae8a2db83e8b47204eee9c71ffbf5e020e88a6e23b", "doi": "", "title": "Immigrant Networks and the U.S. Bilateral Trade: The Role of Immigrant Income", "author": "Kusum Mundra ", "keyword": "immigrant networks, immigrant assimilation, demand effect, trade", "abstract": "demand effect. First, we examine the effect of immigration on trade when the immigrants consume more of the goods that are abundant in their home country than the natives in a standard Heckscher-Ohlin model and find that the effect of immigration on trade is a priori indeterminate. Our econometric gravity model consists of 63 major trading and immigrant sending countries for the U.S. over 1991-2000. We find that the immigrants’ income, mostly through the demand effect, has a significant negative effect on U.S. imports. However, if we include the effect of the immigrant income interacted with the size of the immigrant network, measured by the immigrant stock, we find that the higher the immigrant income the lower is the immigrant network effect for both U.S. exports and imports. This we find in addition to the immigrant stock elasticity of 0.27% for U.S. exports and 0.48% for U.S. imports. Capturing the immigrant assimilation with the level of immigrant income, this paper finds that the immigrant network effect on trade flows is weakened by the increasing level of immigrant assimilation. ", "pub_time": "2010"}
{"sha256": "36ed0e20626c0cf879b617e8d054171a7207cec45e0213ed84903be454ad6613", "doi": "", "title": "Trainspotting: “Good Jobs”, Training and Skilled Immigration", "author": "Andrew Mountford, Jonathan Wadsworth", "keyword": "immigration, training, income distribution", "abstract": "While skilled immigration ceteris paribus provides an immediate boost to GDP per capita by adding to the human capital stock of the receiving economy, might it also reduce the number of ‘good jobs’, i.e. those with training, available to indigenous workers? We analyse this issue theoretically and empirically. The theoretical model shows how skilled immigration can affect the sectoral allocation of labor and how it may have a positive or negative effect on the training and social mobility of native born workers. The empirical analysis uses UK data from 2001 to 2018 to show that training rates of UK born workers have declined in a period where immigration has been rising strongly, and have declined significantly more in high wage non-traded sectors. At a more disaggregated level however this link is much less strong, though there is evidence of different training effects of skilled immigration across traded and non-traded sectors. Hiring of UK born workers in high wage non-traded sectors has also been negatively affected by skilled immigration, although this effect is not large. Taken together the theoretical and empirical analyses suggest that skilled immigration may have some role in allocating native born workers away from ‘good jobs’ sectors but it is unlikely to be a major driver of social mobility.", "pub_time": "2019"}
{"sha256": "35d9370af0422255131af6f3d6a19e35ee42c5a9d12c625d7d287fa05bafc3cd", "doi": "", "title": "Salafism, Jihadism and Radicalisation: Between A Common Doctrinal Heritage and The Logics of Empowerment", "author": "Mohamed-Ali Adraoui", "keyword": "", "abstract": "", "pub_time": "2019"}
{"sha256": "a1381ae5a95fa216f16f9baf0f8187700e91fcf4e4f9de8837921fddc7a6e2ce", "doi": "", "title": "The Birth of Energy", "author": "CARA NEW DAGGETT ", "keyword": "", "abstract": "", "pub_time": "2019"}
{"sha256": "6b95384ae4eac82970b626d2c5f3b75abb9f4e107106a35d4d65dd5577baaca0", "doi": "", "title": "Occupy in Deutschland", "author": "Lars Geiges ", "keyword": "", "abstract": "", "pub_time": "2024"}
{"sha256": "6b94a541a1981320a420c4fc51e18376514cd6f113dbd8759a94a8ee5463cb55", "doi": "", "title": "The Quest for Security in the Age of Austerity: Opportunities and Challenges", "author": "Alexandra Gheciu", "keyword": "", "abstract": "Addressing the issue of transatlantic security in times of defense budget cuts, this article provides operational solutions to improve burden-sharing and enhance NATO’s strategic relevance in the coming decades. It analyzes how Smart Defense could help transatlantic partners balance their defense effort and military engagement in the world. It also examines the necessary evolutions that will be experienced by NATO in the near future, especially in terms of integration of new global partners. ", "pub_time": "2013"}
{"sha256": "6b9edf6dd2530e8749fdc52a273548686a6f505901820a7717845dc15080275e", "doi": "", "title": "Other Native Modernists: What’s in a Name", "author": "J. J. BRODY", "keyword": "", "abstract": "", "pub_time": "2006"}
{"sha256": "d7ec0faf5d4e01efb7fef15b757dd67239d41e92862add1eeb2a4c59593bd8a8", "doi": "", "title": "Problems of Tellability in German Eighteenth-Century Criticism and Novel-Writing ", "author": "karin Kukkonen ", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "00df989a261c11af3782fb74518e688c48096f2bb06efb3671af640479bc8382", "doi": "", "title": "The Qur’an and the Sunnah", "author": "Ismaʿīl Rājī al Fārūqī, Lois Lamyā’ al Fārūqī", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "0000314f63bbd57f113f99fe2346e815e5307ac8e32c6d29cd6460ea45a854f1", "doi": "", "title": "城市分布式泵站排水系统综合节能与协调优化控制研究", "author": "何中杰", "keyword": "分布式泵站排水, 综合节能, 协调优化调度, 多目标, 机泵群, 分层控制结构", "abstract": "城市排水系统属多输入、多目标的广地域分布复杂非线性祸合系统，不合理的排放控制方式易造成泵站高能耗及污水溢出污染。针对城市分布式泵站排水系统综合节能与协调优化控制问题，本论文主要研究内容和成果如下：\n（1）建立了基于机泵群控制、具有时滞和相互链级关系的分布式泵站排水控制系统模型。依据机泵相似律推导出调速特性模型通式，以及基于指数律的机泵调速特性数值模型。探讨了一种基于机泵调速特性模型的实时流量优化测算方法，通过实验检验了该方法的有效性。\n（2）以分布式泵站的节能运行为目标，分析了降低静扬程和动扬程的综合节能机理，并给出了适用于不同工况的两种机泵调速节能优化方法针对扬程变化幅度大且不易控制、或扬程与机泵效率比值不满足递减规律的工况，推导了机泵保持等效运行的充要条件，从而得到一种跟随静扬程变化的自适应高效控制法对于静扬程易自主调节且扬程效率比可满足递减规律的一类工况，综合考虑机泵功率与效率，可得依据扬程效率比的节能法。通过实验比较了两种节能控制法的节能效果。\n（3）针对广地域城市排水系统的协调优化需求，以及引入网络控制后带来的控制品质下降问题，构造了城市排水系统的分层协调控制结构。推导求证了区域泵站控制系统可控和可观测的充要条件。给出了一种初值匹配参数自适应辨识方法，以及结合该方法的多模型预测函数控制法仿真结果表明，将该方法用于区域泵站的闭环控制，系统辨识效果优于采用模型的参数辨识方法，且具有较好的控制鲁棒性。\n（4）为改善广地域分布系统工况差异性带来的合流制溢流分流制溢流问题，提出了一种适用于分布式泵站排水系统的流量协调优化调度方法引入相互作用预测法，结合流量协调优化调度法，将最优控制转化为最优控制和协调优化调度的多目标综合协调优化。仿真结果表明，当入流量不超过各级泵站的排水能力之和时，综合协调优化能根据工况差异有效利用各分布泵站排水能力，确保全局无溢流，不受时滞和决策变量变化的影响。\n（5）设计了一个基于开放标准以太网和的多回路并行网络结构，实现了城市分布式泵站排水网络控制系统中多类型、多回路控制器的网络协调优化调度，为基于分层控制结构的分布式泵站排水系统综合协调优化控制提供了软件平台。", "pub_time": "2009"}
{"sha256": "0002205447c043bc5a288c5a098b7d1eb20290b9f11713721144390b24dab451", "doi": "", "title": "鸡肉的热致变化研究", "author": "吴兵", "keyword": "三黄鸡, 清远麻鸡, 鸡胸肉, 鸡腿肉, 加热, 盐腌, 热致变化", "abstract": "本论文对三黄鸡和清远麻鸡的鸡胸肉和鸡腿肉在不同加热温度、时间及盐腌条件下的物理化学变化、嫩度、质构和肌纤维微观结构进行了研究和比较，初步探索肌肉蛋白在加热和盐腌条件下各种特性的变化机制及其对鸡肉品质的影响。具体研究内容和结果如下：\n1、分别研究了在55℃、65℃、75℃、85℃、95℃下加热30min后，三黄鸡和清远麻鸡鸡胸肉和鸡腿肉的理化特性、嫩度及组织学状态的变化情况。结果表明：\n（1）三黄鸡与清远麻鸡鸡胸肉和鸡腿肉的蒸煮损失分别在65~85℃和55~85℃间显著增加（p＜0.05），三黄鸡胸肉、腿肉的蒸煮损失比清远麻鸡的大；两种鸡种鸡腿肉在55-65℃间蒸煮损失比相应的鸡胸肉小，但是在温度超过75℃后，鸡腿肉的蒸煮损失大于相应的鸡胸肉。\n（2）与生肉相比，热处理后鸡胸肉、腿肉pH值显著增大（p＜0.05），之后随温度的升高，pH变化不明显；清远麻鸡鸡胸肉pH值比三黄鸡的大，鸡腿肉pH值比鸡胸肉的大。\n（3）加热后鸡胸肉的亮度值L*和黄度值b*显著增加（p＜0.05），之后随温度升高变化不明显，红度值a*变化不显著（p＞0.05）；鸡腿肉亮度值在受热后先增大，在65℃时达到最大值后又开始略有减小；黄度值则先显著增大（p＜0.05），在75℃时达到最大后则变化不显著（p＜0.05）；红度值随温度的升高呈现极显著下降趋势（p＜0.05）。\n（4）随着热处理温度的升高，两种鸡胸肉、腿肉的硬度显著增大（p＜0.05）；咀嚼性、弹性及恢复性先显著增大（p＜0.05），在65-75℃时达到最大值后又显著降低；鸡胸肉硬度和恢复性比腿肉大，腿肉的弹性和咀嚼性比胸肉大，清远麻鸡鸡胸肉比三黄鸡鸡胸肉的硬度小，弹性、恢复性和咀嚼性大。\n（5）鸡胸肉剪切力在65℃时剪切力值达到最小，之后在75~85℃之间又显著增大（p＜0.05）；鸡腿肉剪切力值随着温度的升高不断增大，三黄鸡鸡腿肉在55-75℃间剪切力值增加不显著（p＞0.05），在85-95℃间剪切力显著增加（p＜0.05），而清远麻鸡鸡腿肉在55-65℃间剪切力值增加不显著（p＞0.05），在65-85℃间显著增加（p＜0.05），之后随温度继续升高，剪切力值不存在明显变化；总体上清远麻鸡鸡胸肉加热后剪切力大于三黄鸡，鸡腿肉剪切力值大于胸肉剪切力值。\n（6）随着温度的升高，鸡肉盐溶性蛋白溶解度不断减小，在75℃后变化不明显，且鸡种和鸡肉部位间的差异不显著（p＞0.05）；随着加热温度的增加，热溶性胶原蛋白溶解度不断增大，鸡腿肉的热溶性胶原蛋白溶解度大于鸡胸肉。\n（7）从扫描电镜呈现的肌肉组织微观结构图可以得出如下变化规律：55℃时肌内膜和肌束膜发生轻微的弱化收缩，与肌纤维发生初步分离；65℃肌纤维结构发生明显收缩，肌纤维直径显著减小，肌纤维空隙清晰明显，肌内膜和肌束膜与肌纤维出现明显分离；75℃肌内膜和肌束膜完整性结构受到破坏，颗粒化现象更明显，肌纤维间隙有所减小；85℃颗粒化物质明显减少，肌纤维间进一步减小，肌纤维直径继续增大；95℃相邻肌纤维彼此排列紧实、致密，肌肉硬度在此时达到最大。\n（8）随着温度的升高，鸡胸肉的肌纤维直径在分别在55-65℃和65-75℃两个温度区间内出现显著减小和显著增大（p＜0.05），而在75-95℃间变化不明显（p＞0.05）；温度及鸡种对鸡腿肉肌纤维直径变化的影响不显著（p＞0.05）。\n（9）鸡肉全肌蛋白电泳图谱表明，大部分的蛋白条带如热稳定性较强的肌动蛋白在加热前后无明显变化，受热后伴有新的小分子蛋白条带产生和消失，而渗出液电泳图谱在75℃以上时检测出新的高分子量胶原蛋白谱带β，α1以及α2。\n2、研究了80℃下，鸡胸肉和腿肉分别加热5min、10min、15min、20min、30min、40min后的热致变化情况。结果表明：在加热5-15min内，鸡肉蒸煮损失显著增加（p＜0.05）；在0-20min内鸡肉硬度、咀嚼性和弹性变化显著（p＜0.05），在加热30-40min内各指标无显著变化，说明在加热初期0-30min时间段内对鸡肉品质影响最为关键；在20-40min内剪切力值增加显著。\n3、以鸡胸肉为原料，经浓度分别为0、2%、4%、6%（w/w）食盐溶液浸渍12h后，再经80℃加热30min，研究食盐溶液浓度对鸡肉热致改变的影响。结果如下：盐溶液浓度的增加，胸肉中肌球蛋白和肌动蛋白变性温度逐渐向低温方向移动；盐溶液浸渍处理对鸡胸肉肌原纤维蛋白的崩解起促进作用，肌原纤维结构棱廓模糊，经2%和4%氯化钠溶液处理鸡肉样的剪切力显著减小。", "pub_time": "2011"}
{"sha256": "000237ed5d4d8f1af951619678f3b5c745d3f7a8129aab71570435198bc79492", "doi": "", "title": "情商、逆商与工作绩效研究", "author": "周蓓蓓", "keyword": "情商, 逆商, 绩效, 正相关, 人力资源管理", "abstract": "随着科学技术的进步和经济的飞速发展，人们所面对的竞争和环境也日趋激烈和复杂。越来越多的人们意识到一个人的成功不单单依靠智商，而是各种能力综合作用的结果。因此各种商数名词随之产生，例如情商、逆商等。情商也称为情绪智力，是一个人后天形成的自我情绪认知、他人情绪认知、自我情绪管理、他人情绪管理能力的总和。逆商也称为逆境商，是一个人面对逆境、摆脱逆境和战胜逆境的能力。情商理论和逆商理论在世纪末盛行起来并得到广泛的关注和研究。但是情商和逆商作为一个心理学名词，关于它的研究多集中在心理学和教育领域，与其他学科的结合研究比较少。\n情商、逆商理论在我国的发展还处在比较年轻的阶段，为了充实我国现有的情商和逆商方面的研究，使人力资源理论得到充实，特进行此研究。\n本研究首先对情商、逆商理论的产生和发展进行梳理，然后从情商和逆商的定义与理论维度出发，在国内外研究的基础上，设计实验，做出两个假设：\n1、情商和绩效之间存在显著地正向关系，即情商越高，工作绩效越高；\n2、逆商和绩效之间存在显著地正向关系，即逆商越高，工作绩效越高。\n通过调査问卷对国有企业和私营企业的员工的情商、逆商和绩效水平进行调查，运用和软件，采用相关分析和回归分析的技术方法，分别对情商与绩效、逆商与绩效的关系进行了研究，得出数据显示情商、逆商分别与绩效存在很显著的正向关系，假设得到验证。\n现代先进的人力资源管理的发展趋势是由基于工作的转向基于能力的，该能力不仅指技术层面的，也包含精神、心里层面的能力，而且发挥着不可小觑的力量。因而，本研究对于现代先进的人力资源管理有重要的实践意义：情商可以帮助打破思维定势，整合优化企业的资源，为企业带来新的希望；逆商对绩效的影响贯穿人力资源管理始终，特别是在人力资源的管理的两个重要阶段—输入阶段和输出阶段有显著的作用。基于以上的分析，显然提高情商和逆商是十分有意义的。\n为了使本研究的结论得到更好地应用，本研究也提出了提高情商、逆商的途径和方法，主要有加强理论教育和增加拓展性训练两个途径。理论教育可以帮助人们对于情商、逆商的定义和内容有清晰的了解，拓展训练可以根据情商、逆商理论的维度和参与者的情商、逆商现有水平设计活动，有针对性的对某一个或几个方面进行提高。\n由于作者理论水平的限制，本研究还存在一些不足之处。本研究的结尾部分提出本研究的不足和对未来发展的展望。", "pub_time": "2012"}
{"sha256": "00025d44ee22725a719b8c7d6b9dde0eff0309c28627ef76687b8ebcc90df36b", "doi": "", "title": "药物与蛋白质的相互作用研究", "author": "李道金", "keyword": "", "abstract": "人血清白蛋白（HSA）是体内最重要的转运蛋白质，能和许多内源和外源性的物质如代谢物、药物和其它具有生物活性的化合物结合，起到在储存和转运作用。因此对药物等小分子与 HSA 的相互作用的研究有助于理解药物的分配、传输、代谢和功效。溶菌酶（Lys）是一种球状蛋白质，具有水解细菌细胞壁杀死细菌的作用。过氧化氢酶（CAT）是一种重要的抗氧化剂，它能把过氧化氢分子氧化分解为水和氧气。Lys 和 CAT 像 HSA 一样也能和许多小分子物质如药物结合，从而对药物的代谢和功效以及酶的活性等产生影响。该领域已成为从事生命科学、化学和临床医学科研工作者共同关注的课题之一。本论文基于开展小分子与蛋白质相互作用的重要意义及国内外研究趋势，在前人工作的基础上，综合利用荧光光谱、紫外-可见吸收光谱、圆二色谱和计算机分子模拟技术，从以下几方面进行了创新性研究：\n1. 研究了模拟生理条件下石吊兰素与几种蛋白质（HSA，Lys 和 CAT）的相互作用。根据 Stern-volmer 方程等研究了石吊兰素与蛋白质结合的作用机制（包括荧光猝灭机理、结合常数和结合位点数），并且计算了结合距离，讨论了主要作用力类型。\n2. 探讨了 Stern-volmer 曲线向上弯曲的原因。\n3. 利用圆二色谱考察了石吊兰素对蛋白质二级结构的影响。\n4. 研究了石吊兰素对 Lys 和 CAT 活性的影响。\n5. 用计算机模拟方法研究了石吊兰素与 HSA 的对接，获得与试验一致的结果。\n论文共分为三部分：\n第一章：简要介绍了蛋白质的结构、功能和性质综述了小分子物质与蛋白质相互作用的研究方法以及研究现状等。\n第二章：利用荧光光谱、圆二色谱和分子模拟研究了模拟生理条件下石吊兰素与人血清白蛋白（HSA）的相互作用。实验结果表明，石吊兰素通过静态机理猝灭 HSA 的内在荧光，计算了不同温度下药物与 HSA 相互作用的结合常数及位点数，分析了药物对 HSA 二级结构的影响，并根据热力学参数确定了作用力类型。分子模拟结果显示药物很好地结合在 HSA 的 II A 子域（位置 I）。\n第三章：利用荧光光谱、圆二色谱和酶的活性实验研究了模拟生理条件下石吊兰素与溶菌酶（Lys）和牛肝过氧化氢酶（BLC）的相互作用。系统阐述了石吊兰素猝灭 Lys 和 BLC 的内在荧光的机理。计算了不同温度下药物与 Lys 和 BLC 相互作用的结合常数及位点数，探讨了药物的结合对 Lys 和 BLC 构象产生的影响。热力学分析可知，药物与 Lys 或 BLC 之间主要以硫水作用为主。此外，Lys 和 BLC 的酶活性试验表明石吊兰素与 Lys 和 BLC 的结合引起了酶活性的减少。", "pub_time": "2007"}
{"sha256": "000279ef9e3b9a74c2553b14145311854ac0675987e2ac31c980b3c40cb7eb64", "doi": "", "title": "关于静电开关动态响应的数学分析", "author": "赵乐", "keyword": "微电子机械系统, 静电开关, 能量方法", "abstract": "本文首先简要介绍了微电子机械系统的各种模型, 前人已做的工作, 发展前景等背景知识以及本文的主要结论.\n其次研究了静电开关动态响应中不含阻尼项的达芬系统, 得到周期解的存在条件和非周期解的存在条件.\n再次研究了静电开关动态响应中含阻尼项却不含非线性劲度的方程, 得到局部解的存在性, 整体解的存在条件和平衡解的稳定性.", "pub_time": "2010"}
{"sha256": "000343a05a5d4067e99521a67512348d25070ad001639b4129641e89fe9d86f9", "doi": "", "title": "剪力墙结构在地震作用下的Pushover分析研究", "author": "侯少颖", "keyword": "剪力墙结构, 地震作用, Pushover 分析, 破坏机理, 加载模式, 非线性时程分析, 薄弱层", "abstract": "由于国民经济的飞速发展和人口数量的增长，大量的高层建筑不断涌现，剪力墙作为一种有效的抗侧力构件得到广泛应用，近年来世界各地的地震也显示出剪力墙在结构安全体系中扮演着很重要的角色。Pushover分析 (也称为非线性静力分析)被认为是基于性能设计中一个重要的工具，已被引入我国新的建筑结构抗震设计规范，很多学者对该分析方法进行了不同方面的研究，但是该方法在结构分析中的合理运用仍然存在许多问题。本文主要采用Pushover分析对剪力墙结构体系进行分析和探讨。\n首先对不同类型剪力墙结构在地震作用下的破坏机理进行了研究，论述了其现状和进展。由此可知目前对于剪力墙结构的破坏形态主要是针对结构的某个部分进行研究，而对整体剪力墙抗震性能评估的研究甚少。因此本文对整体剪力墙结构在强烈地震作用下受力特性和抗震性能进行分析研究，有很强的理论与工程应用价值。\n由于Pushover分析方法目前处于研究阶段，对于加载模式的合理运用还有待探讨，本文分别采用均匀分布、倒三角分布和多振型分布三种水平加载模式对一座12层整体剪力墙结构进行分析，并与非线性时程分析结果相对比，探讨加载模式选取的合理性。\n最后得出Pushover分析在考虑高阶振型影响的情况下得到的结果更加准确可靠，通过楼层的层间位移角、二阶差值位移角曲线判断出整体剪力墙结构的薄弱层，为剪力墙结构在Pushover分析中侧向力的选取提出了建议。", "pub_time": "2008"}
{"sha256": "0003a71ad024cad65e1a403ff3e784c1c13da77b09f2bc06dd911b58218c2d36", "doi": "", "title": "慢性间歇性低压低氧对发育大鼠心脏的保护作用及其热休克蛋白机制", "author": "布会敏", "keyword": "慢性间歇性低压低氧, 热休克蛋白, 急性低氧/复氧, 心脏功能, 大鼠", "abstract": "目的：大量研究表明，慢性间歇性低压低氧（CIHH）对成年大鼠具有明显的心脏保护作用，显著提高心肌抗缺血/再灌注或缺氧/复氧损伤能力，减轻缺血/再灌注后心脏舒缩功能的降低，预防缺血/再灌注心律失常的发生。幼年动物心脏与成年动物心脏在形态、功能等多方面存在差异，而有关CIHH对发育心脏作用的研究甚少。亦未见有关CIHH对发育大鼠心脏热休克蛋白表达的研究报道。本研究旨在应用功能学及分子生物学方法探讨CIHH对发育大鼠心脏的保护作用，及其热休克蛋白机制。\n方法：60只新生雄性Sprague-Dawley（SD）大鼠，随机分为六组：CIHH处理28天组（CIHH28）、CIHH处理42天组（CIHH42）和CIHH处理56天组（CIHH56）、28天对照组（Con28）、42天对照组（Con42）和56天对照组（Con56）。CIHH动物（连同母鼠）置于低压氧舱，分别接受28、42、56天相当于3000米海拔（Pb=525mmHg, P₀₂=108.8mmHg）低压低氧处理（5hrs/day）。对照组动物除不给予慢性低氧外其余处理同CIHH动物。应用导管法描记动脉血压（BP）、心率（HR）、左室收缩压（LVSP）、左室舒张末压（LVEDP），左室压力最大变化速率（±LVdp/dtmax），并观察急性低氧/复氧对其影响。应用半定量RT-PCR和Western-blotting技术检测各组动物心肌热休克蛋白 27（HSP27）、热休克蛋白 70（HSP70）和热休克蛋白 90（HSP90）mRNA 及蛋白的表达。\n结果：1、常氧状态下，Con 各组动物左心室功能无明显差异（P>0.05）。Con28 大鼠 HR 明显快于 Con42 和 Con56 大鼠（P<0.05）；CIHH28 组动物 LVSP 和 +LVDp/dtmax 明显高于 CIHH42 和 CIHH56 组动物（P<0.05）。CIHH28 组动物 LVSP 亦明显高于 Con28 动物（P<0.05）。急性低氧/复氧导致大鼠心功能损伤，表现为 BP、HR、LVSP 和±LVDp/dtmax、LVEDP 升高（P<0.05），但 CIHH 大鼠各心功能参数变化明显小于对照动物（P<0.05）。CIHH 动物相比较，CIHH28 动物抗心肌急性低氧/复氧损伤作用明显好于 CIHH42 和 CIHH56 动物（P<0.05）。\n2、常氧状态下，各组动物 HSP mRNA 表达无明显差异（P>0.05）。急性低氧/复氧状态下，Con 动物 HSP90 mRNA 表达均明显增加（P<0.05）；CIHH 动物 HSP27 mRNA、HSP70 mRNA 和 HSP90 mRNA 表达均显著增加（P<0.05），而 CIHH28 动物 HSP70 mRNA 和 HSP90 mRNA 表现尤为突出（P<0.05）。与 Con 动物相比较，CIHH 动物 HSPs mRNA 表达明显增加（P<0.05）。\n3、常氧状态下，28 天 Con 组动物左心室 HSP 蛋白表达明显高于 42 天和 56 天 Con 组（P<0.01）；CIHH 能增强大鼠 HSP27、HSP70 和 HSP90 蛋白基础表达（P<0.05-0.01），且 CIHH28 大鼠三种 HSPs 表达明显高于 CIHH42 和 CIHH56 大鼠。急性低氧/复氧导致所有动物 HSP27、HSP70 蛋白表达增加（P<0.05），而 CIHH 动物 HSPs 蛋白表达明显大于 Con 动物（P＜0.05），CIHH28 动物 HSPs 表达最为显著。\n结论：慢性间歇性低压低氧可通过增加心肌热休克蛋白 mRNA 及其蛋白表达，增强发育大鼠心脏抗急性低氧/复氧损伤能力。", "pub_time": "2009"}
{"sha256": "0003b072855d77add5fdd4c8e9c39b51661ed7233dc02c4e03e93b5bb19e6e6a", "doi": "", "title": "木兰县农业保险发展对策研究", "author": "刘赛", "keyword": "农民, 灾害, 农业保险, 体系建设", "abstract": "农业作为农民生产生活的根本，是全国各行业赖以运行的根本，也是国民经济发展的根本。然而，农业生产是存在较大风险的，尤其木兰县的种植业由于地形、地貌等各种自然原因导致风险相对较大，这就迫切要求加快木兰县农业保险体系建设。年“中央一号文件”明确提出加大农业保险支持力度。鼓励保险机构开展特色优势农产品保险，有条件的地方提供保费补贴，中央财政通过以奖代补等方式予以支持。可见政府在农业保险的发展方面将做出较大的投入，也只有通过政府的政策扶持，农业保险才能够快速稳定的发展。\n文中运用定性分析与定量分析相结合的方法，对黑龙江省木兰县种植业的农业保险体系建设进行了分析，通过分析可以看出，尽管近年来木兰县的农业保险发展较为迅速，但是从整体来看，仍然存在极大的发展空间。本文首先对当前木兰县农业保险的发展现状进行了描述，从侧面提出了木兰县发展农业保险的必要性；其次，分析了木兰县农业保险发展中存在的问题及影响因素，再次，根据实际提出的问题给出了相应的对策建议。\n本文综合运用外部性理论、市场失灵理论、信息不对称理论、马克思关于农业保险的理论以及新制度经济学理论等相关理论，以木兰县农业保险为研究对象，运用文献法、定性分析与定量分析相结合以及静态分析和动态分析相结合等研究方法，在研究思路上，对国内外关于农业保险的相关研究成果进行梳理，以形成本研究的切入点，以此为基础，对木兰县农业保险现状进行分析，阐述木兰县农业发展现状、农业灾害概况、农业保险机构概况，并对木兰县农业保险市场进行调查，研究发现木兰县农业保险的发展中存在农购买力与购买意愿低、农民投保意识低、投保人结构恶化、法制不完善、农业保险经营技术落后、政府补贴尚欠完善以及政府政策引导力不足等问题，最后，根据木兰县农业保险发展过程中存在的问题提出针对性的对策建议。木兰县以种植业为主，具有较强的事实根据和较强的代表性，本人查阅大量资料，对每一个不同的问题都从不同的角度加以分析并提出对策。希望本文具有较强的理论指导意义和应用价值，以期在农业保险存在的问题及相应解决对策方面有所贡献。", "pub_time": "2014"}
{"sha256": "0003dc81b5ce900463c964ccdeaf3e4e4711e9d5682b94ee974845614f93d4ab", "doi": "", "title": "非利息收入对我国上市商业银行风险的影响研究", "author": "吴雨翘", "keyword": "商业银行, 非利息收入, 银行风险", "abstract": "原先严格的分业经营制度在一定程度上限制了我国资本市场与货币市场的联系，随着近年来我国逐步放松对外资银行、民营资本准入的限制，利率市场化进程的实质性改革，社会融资方式的多样化均导致间接融资规模及占比逐年下降，商业银行传统的利差模式已经无法满足其稳健增长的目标，银行业愈发感受到金融脱媒带来的阵阵凉意，开始将新的利润增长点放到了非利息业务上。年起我国商业银行非利息收入增长率已经超越净利息收入，进入蓬勃发展时期，但是在大力发展非利息业务的进程中，也应该理性的认识到，商业银行开展的非利息业务在带来效益的同时是否会改变银行的风险状况。\n从商业银行的非利息业务出发，本文首先简要介绍了国内外相关文献的研究成果，并对非利息收入的相关概念、发展背景及其必要性进行了梳理，然后分析了我国上市商业银行年的非利息业务发展情况。实证部分，首先阐述了非利息业务与银行风险之间关系的理论基础及风险传导机制，并在此基础上建立回归模型，选取我国家上市商业银行年第季度到年第季度的面板数据，对非利息收入与银行风险之间的关系进行了考察并得出以下结论：（1）手续费及佣金收入占比与银行风险之间呈负相关关系，即手续费及佣金收入占比的增加会导致银行风险的减少；（2）投资收益占比与银行风险呈正相关关系，即投资收益占比的提高会加剧银行风险；（3）除此以外的其他非利息收入包括公允价值变动损益、汇兑损益、其他业务收入三者在内的占比与银行风险的关系不显著，但系数显示此项收入占比的增加会减小银行风险；（4）非利息收入中具备降低银行风险功能的业务恰好构成中间业务，商业银行应大力发展中间业务。最后结合发展现状与实证分析结果，为我国商业银行发展非利息收入提供一些新的思路，以期对商业银行业务转型及风险控制优化起到指导和警示意义。", "pub_time": "2014"}
{"sha256": "0004d4a281d3c427d2a640ad32766538e63bb4dbf0efa3318a27515ca3858736", "doi": "", "title": "企业全面预算管理优化研究--以 G 公司为例", "author": "白芸萱", "keyword": "全面预算管理, 经营预算, 预算优化", "abstract": "全面预算管理在现代社会和现代的单位中，是一种综合而又全面的管理系统，它不断地引起各类单位的不断重视，并且全面预算管理系统在单位实现自己经营目标水平上发挥着让人意想不到的作用，努力推进全面预算管理成了企业的投资者和经营高管人员在当今新形势之下的必然选择,是现代国有企业和大型企业中财务管理与经营管理高度融合下的一种管理方式，也是公司内部控制的一种主要综合的手段。它从一开始的计划变成到目前的既能控制、又能评价这一系列功能的全面性的、实现公司经营战略的预算系统。实践证明，要想强化单位的经营风险管控能力，使单位的发展能力和综合价值达到一个更好的平台，以及使得单位领导可以更好的掌控公司和使单位创造利润的水平达到一个更高的水平，进而更好的达到提升公司经营水平，那么就可以通过运用完善的全面预算的系统。\n预算管理水平需要进一步的提高和发展，在我国相当部分的企业中都是只重视财务方面的预算，只看重现金的掌控，涉及的范围比较狭窄，不广泛。即使在财务预算中也只是单纯的编制一些企业在管理方面必须的支出和一些为了销售商品等连带的支出。而且，现在大多数的电力企业对企业预算的重视还提不上日程，它分析的内容比较简单。而且这个理论在以电为主营业务产品的这个行业的起步比较慢也比较迟，加上这个行业的特征也特别具有它自己的独特性，在单位的进一步实施中有不少主观的思想方面和实践上的误区，他的科学性和合理性还等着更好的发展。在上述背景下，本论文主要内容是在G单位全面预算管理的编制过程中，通过全面预算管理的相关理论概念，进而引出G单位的现在基本情况的概述，然后通过大量篇幅说明它从始至终的编制过程。来分析G单位在编制中发挥出来的作用以及G单位在全面预算中存在的问题，最后根据在编制过程中发现的问题来提出解决问题的有针对性的建议。这样，为G单位以后作为电力企业的龙头企业可以在市场上越走越远奠基。", "pub_time": "2017"}
{"sha256": "00053682a299304c88c99ff25264c9a245515887595e1c7c6ce0c4205ffa030a", "doi": "", "title": "儿童生长发育状况与血液微量元素浓度的相关性研究", "author": "陈亚楠", "keyword": "儿童, 健康管理, 体格生长, 微量元素, 相关性", "abstract": "目的：以儿童生长发育及儿童健康管理为理论基础，了解不同性别、不同年龄组儿童的生长发育状况与血液微量元素浓度情况，分析不同生长发育状态下血液微量元素浓度差异性及血液微量元素与儿童生长发育的相关性，进一步探索不同血液微量元素之间的相关性，为临床及日常生活中应用微量元素促进儿童良好的生长发育提供研究依据，不断提升儿童的健康及营养水平。\n方法：选取2015年12月~2016年12月浙江省某市级妇幼保健院儿保科716名儿童为研究对象，通过实验室检测和体格测量获取其血液微量元素浓度和体格生长情况，采用标准差离差法对体格生长测量值和微量元素测定值进行标化，利用独立样本t检验比较不同性别的血液微量元素浓度差异，卡方检验比较不同性别、年龄组微量元素的异常率，方差分析比较不同年龄组、不同体格生长水平下儿童血液微量元素的差异，利用Pearson相关分析了解儿童生长发育情况与血液微量元素间的相关性及微量元素之间的关联，多重线性回归了解不同血液微量元素对体格生长状况影响的程度。\n结果：\n（1）基本情况716例研究对象中男童418例（58.3%），女童298例（41.7%）；婴儿期0~1岁组34例（4.8%），幼儿期~3岁组138例（19.3%），学龄前期~6.5岁组191例（26.7%），学龄期~15岁组353例（49.2%）。716例研究对象中低血锌47例（6.6%），低血铁46例（6.4%），低血钙75例（10.5%）；高血铅3例（0.4%），高血锌1例（0.1%）。\n（2）不同性别、年龄组儿童血液微量元素的比较男童血铅元素浓度高于女童，男童血钙浓度低于女童（p＜0.05）；男女微量元素异常率比较差异无统计学意义（p＞0.05）。不同年龄组血液微量元素浓度差异有统计学意义（p＜0.05），其中铅、锌、铁浓度随着年龄的增长呈现增高的趋势，而铜、钙、镁元素则相反。各年龄组低铁、低锌、低钙发生率比较有统计学意义（p＜0.05）：1~3岁组低铁率最高，6~15岁组低锌率、低钙率高与其他三组。\n（3）不同生长发育状况的血液微量元素的比较身高、体重处于低水平组儿童的血锌浓度均低于其中等水平和高水平组的血锌浓度，BMI低水平组的血锌浓度高于其中等和高水平组的血锌；身高、体重、BMI处于低水平组儿童的血铁浓度低于其高水平组的血铁，BMI低水平的血铁低于其中等水平的血铁；身高、体重、BMI低水平组的血镁低于其高水平组的血镁，BMI低水平的血镁低于其中等水平的血镁；骨龄延迟组的血锌、血铁低于骨龄超前组的血锌、血铁浓度。\n（4）儿童生长发育状况与血液微量元素的关系在本研究的取值范围内，血液锌、铁、镁均与身高、体重水平呈正相关，血锌对身高、体重影响较大（p＜0.05）；血液铁、镁与BMI水平正相关，血锌与BMI水平显著负相关，血铁对BMI的影响较大（p＜0.05）；血液微量元素与骨龄的相关无统计学意义（p＞0.05）；血液铅、钙、镁、铜对身高、体重及BMI影响无统计学意义（p＞0.05）。\n（5）血液微量元素之间的关联血液铜、铁浓度与铅浓度呈负相关（p＜0.05）；血液铜、铁、钙浓度与血锌浓度呈正相关，与血镁浓度呈正相关（p＜0.05）；血钙浓度与血铜浓度显著正相关，血镁浓度与血锌浓度正相关（p＜0.05）。\n结论：\n（1）0~15岁儿童存在明显的血液低钙、低铁、低锌及高铅情况，低钙人数最多。\n（2）男童血铅浓度高于女童，血钙浓度低于女童;血液铅、锌、铁浓度随着年龄增长呈现增加趋势，铜、钙、镁则相反。\n（3）身高、体重均与血液锌、铁、镁正相关，BMI与血液铁、镁正相关，但与血锌负相关，骨龄成熟情况与血液微量元素相关无统计学意义。\n（4）血锌浓度对身高、体重影响较大，血铁浓度对BMI影响较大。\n（5）血液微量元素之间存在紧密的关联。", "pub_time": "2017"}
{"sha256": "000693c617b12970a753a6f60478388064d5cc499950c7a485eb0dc5d0d8d6fa", "doi": "", "title": "明代文昌信仰研究", "author": "刘娇娇", "keyword": "明代, 文昌信仰, 文昌宫, 科举神", "abstract": "文昌帝君是掌管士人功名利禄的神祇。文昌信仰伴随着科举制度的发展在中国延续千年，对中国政治思想、文化教育和社会生活等方面都产生了重大而深刻的影响。明代是文昌信仰发展的关键时期，而学界系统论述明代文昌信仰的成果颇少，本文分以下三方面论述了明代文昌信仰。\n明代文昌帝君的神职已集中到执掌功名桂籍上，而其余神职，如掌管生育、庇护官员，或多或少均与其掌功名桂籍相关。而唐宋时期惩治内叛，抵御外敌之职，在明代已消失无踪。与之相适应，文昌帝君武将形象消失，文职官员形象则成为明代最为普遍的形象。同时文昌帝君有了自己的神灵体系，有了侍从天聋和地哑。随着文昌信仰的发展，文昌宫祠遍布全国，在经济发达的江南地区更是普遍。同时出现了与文昌帝君相关的民俗，如敬惜字纸、文昌洞经音乐。\n文昌帝君的地位在明代起伏较大。明初，文昌帝君的发展受到明王朝的支持。明英宗重修京师文昌庙。然弘治元年（1488），明孝宗却同意礼部尚书周洪谟等人贬抑文昌帝君的请求。明王朝对文昌信仰态度的转变，其原因有四：一是弘治初年，明廷财政困难，拆毁文昌祠可省无益之费；二是文昌信仰源流不清，本身存在缺陷；三是崇祀文昌帝君与儒家思想有抵牾；四是明孝宗为肃清社会风气，整顿祀典。明王朝对文昌帝君的贬抑，在执行过程中却因监督不力、政策的倡议者或逝世，或离职、士子对崇祀文昌帝君看法不一及文昌信仰深入人心等原因，明廷的一纸禁令已难以抑制文昌信仰的发展。\n宋时，文昌帝君偶尔有奉祀于学宫的现象。至明代，文昌宫祠普遍附祀于学宫。文昌宫祠普遍附祀学宫的原因有三：一是文昌信仰可弥补科举考试的缺陷；二是修筑文昌宫祠可振兴地方文风；三是士子普遍奉祀。对于文昌帝君附祀学宫，士人意见不一，有持反对意见者，认为文昌信仰源流不清，应撤出学宫。有持支持意见者，认为文昌信仰“在有功于儒教”。", "pub_time": "2017"}
{"sha256": "0006a7d36c53010a9341ef64af25f849bb79a627bc0704690f529ef115b539be", "doi": "", "title": "山东黄金矿业多金属综合回收技术经济分析", "author": "姚福善", "keyword": "黄金,多金属,技术指标,经济分析,评价", "abstract": "黄金矿业企业在我国是一个特殊行业。次贷危机引发的经济通胀使黄金价格居高不下，随着欧美经济的复苏，使得黄金价格牛市已尽。尽管目前黄金市场供不应求，但多数黄金矿业企业已经处于微利宭境，甚至徘徊在成本边缘。通过对黄金矿企多金属综合回收技术经济分析研究，实现对矿产资源的充分利用，达到企业效益的最大化，摆脱企业在成本边缘挣扎的微利局面，为企业的可持续发展提供技术和管理方面的指导。\n本文以山东黄金矿业企业为分析研究主体，通过工艺矿物学研究，在大量的试验数据基础上，从技术、经济、环保等方面分析研究开展多金属综合回收的重要性，从经济效益、社会效益、环境效益分析研究开展多金属回收的必要性；同时对企业多金属综合回收进行相关评价。主要研究内容为：（黄金矿业企业开展多金属综合回收的可行性、必要性以及行业影响。（山东黄金矿业企业开展多金属综合回收的技术分析、经济效益分析、社会效益分析、环境效益分析。（对山东黄金矿业企业开展多金属综合回收的综合评价。通过开展多金属回收利用，达到对矿产资源的充分利用，实现矿业企业向生态矿业的发展，为企业的可持续发展提供技术和经济支撑。所幵展的金精矿工艺矿物学研究，为今后黄金行业的规划、设计、工艺选择提供技术支撑。", "pub_time": "2014"}
{"sha256": "00071bb035f2d148e81cff69d5042fbc73c6110aa319a74f341043e1e4615203", "doi": "", "title": "螺内酯通过miRNA-1调节大鼠心肌梗死后HCN通道蛋白表达的研究", "author": "余华东", "keyword": "心肌梗死, HCN2, HCN4, 螺内酯, miRNA-1", "abstract": "目的：多项研究发现心肌梗死（myocardial infarction, MI）后室性心律失常与超极化活化环核苷酸门控通道（hyperpolarization-activated cyclic nucleotide-gated channel, HCN）基因在心室异常表达密切相关，最新证据已显示醛固酮阻断剂（aldosterone blockers, ABs）减少了心肌梗死病人室性心律失常的发生，但具体机制尚不明确。我们研究探讨了螺内酯调节大鼠心肌梗死后缺血心肌中HCN通道蛋白表达的机制，从而为醛固酮阻断剂在心肌梗死后抗室性心律失常的治疗提供理论基础。\n方法：通过开胸结扎冠状动脉左前降支的方法成功建立大鼠心肌梗死模型，心梗后24小时存活的18只大鼠随机分为三组：MI组，Sham组，螺内酯组。6只Sham组的大鼠仅穿线绕过左冠状动脉前降支而不结扎动脉。心肌梗死后一周取心梗大鼠的梗死周边区心肌组织，而假手术组取相对应的心肌组织，用荧光定量PCR方法检测HCN2、HCN4的mRNA水平和miRNA-1水平，用Western blot方法检测HCN2、HCN4的蛋白水平。\n结果：螺内酯明显增加了心肌梗死后miRNA-1的水平，而下调了HCN2、HCN4的蛋白以及mRNA水平。用antagomir-1沉默miRNA-1后明显增加了HCN2、HCN4的蛋白水平，然而对HCN2、HCN4的mRNA水平却无影响。\n结论：螺内酯能增加心肌梗死后缺血心肌中miRNA-1的表达，而上调的miRNA-1在转录后水平抑制了HCN蛋白的表达，这可能是螺内酯减少心肌梗死相关的室性心律失常发生的机制之一。", "pub_time": "2015"}
{"sha256": "3787764744f1b450239105540b301cc98972669df347549de1fb37fc988f370b", "doi": "", "title": "Transformers for Ischemic Stroke Infarct Core Segmentation from Spatio-temporal CT Perfusion Scans", "author": "Lucas de Vries, Bart Emmer, Charles Majoie, Henk Marquering, Efstratios Gavves", "keyword": "CT Perfusion, Transformers, Ischemic stroke, Infarct core segmentation", "abstract": "The infarct core size is a crucial biomarker for treatment selection for ischemic stroke patients. For this purpose, we present a novel approach to perform infarct core segmentation using CT perfusion (CTP) source data, without ordinary deconvolution analysis. We propose the use of transformers to encode sequential CTP scans in spatial attention maps, which we subsequently use for infarct core segmentation. We report new top results on the ISLES 2018 challenge test data set for infarct core segmentation. This work presents a primary benchmark for infarct core segmentation from CTP source data using transformers.", "pub_time": "2021"}
{"sha256": "3f41052453f7fa670de21ad244fa4cdacd0fd881b015660f12da1c039b98b0eb", "doi": "", "title": "Music Symbol Detection with Faster R-CNN Using Synthetic Annotations", "author": "Kwon-Young Choi, Bertrand Coüasnon, Yann Ricquebourg, Richard Zanibbi", "keyword": "Optical Music Recognition, Deep Learning, Symbol Detection", "abstract": "Accurately detecting music symbols in images of historical, complex, dense orchestral or piano printed scores can be challenging due to old printing techniques or time degradations. Because segmentation problems can vary widely, a data driven approach like the use of deep learning detectors is needed. However, the production of detection annotations (symbol bounding boxes + classes) for such systems is costly and time consuming. We propose to train such model with synthetic data and annotations produced by a music typesetting program. We analyze which classes are relevant to the detection task and present a first selection of music score typesetting files that will be used for training. To evaluate our model, we plan to compute quantitative results on a synthetic test set and provide qualitative results on a few manually annotated historical music scores.", "pub_time": ""}
{"sha256": "e3ac5ad7051eeb4ac9e4aced3d1f770e01dbc3b2be60f4f355cab267d1467842", "doi": "", "title": "Deep Learning for Model Correction in Cardiac Electrophysiological Imaging", "author": "Victoriya Kashtanova, Ibrahim Ayed, Andony Arrieula6, Mark Potse, Patrick Gallinari, Maxime Sermesant", "keyword": "Physics-based learning, Electrophysiology, Deep learning, Simulations", "abstract": "Imaging the electrical activity of the heart can be achieved with invasive catheterisation. However, the resulting data are sparse and noisy. Mathematical modelling of cardiac electrophysiology can help the analysis but solving the associated mathematical systems can become unfeasible. It is often computationally demanding, for instance when solving for different patient conditions. We present a new framework to model the dynamics of cardiac electrophysiology at lower cost. It is based on the integration of a low-fidelity physical model and a learning component implemented here via neural networks. The latter acts as a complement to the physical part, and handles all quantities and dynamics that the simplified physical model neglects. We demonstrate that this framework allows us to reproduce the complex dynamics of the transmembrane potential and to correctly identify the relevant physical parameters, even when only partial measurements are available. This combined model-based and data-driven approach could improve cardiac electrophysiological imaging and provide predictive tools.", "pub_time": "2022"}
{"sha256": "a7901e8444864f582c6675bfc19395cabf4e73885a09411a6b4061e6f912cda1", "doi": "", "title": "Automatic planning of liver tumor thermal ablation using deep reinforcement learning", "author": "Krishna Chaitanya, Chloé Audigier, Laura Elena Balascuta, Tommaso Mansi", "keyword": "Deep reinforcement learning (DRL), liver tumor ablation, thermal ablation, proximal policy optimization (PPO), double deep Q networks (DDQN)", "abstract": "Thermal ablation is a promising minimally invasive intervention to treat liver tumors. It requires a meticulous planning phase where the electrode trajectory from the skin surface to the tumor inside the liver as well as the ablation protocol are defined to reach a complete tumor ablation while considering multiple clinical constraints such as avoiding too much damage to healthy tissue. The planning is usually done manually based on 2D views of pre-operative CT images and can be extremely challenging for large or irregularly shaped tumors. Conventional optimization methods have been proposed to automate this complex task, but they suffer from high computation time. To alleviate this drawback, we propose to leverage a deep reinforcement learning (DRL) approach to find the optimal electrode trajectory that satisfies all the clinical constraints and does not require any labels in training. Here, we define a custom environment as the 3D mask with tumor, surrounding organs, skin labels along with an electrode line and ablation zone. An agent, represented by a neural network, interacts with the custom environment by displacing the electrode and therefore can learn an optimal policy. The reward assignment is done based on the clinical constraints. We explore discrete and continuous action-based approaches with double deep Q networks and proximal policy optimization (PPO), respectively. We perform an evaluation on the publicly available liver tumor segmentation (LITs) challenge dataset and obtain solutions that satisfy all clinical constraints comparable to the conventional method. The DRL method does not need any post-processing steps, allowing a mean inference time of 13.3 seconds per subject compared to the conventional optimization method’s mean time of 135 seconds. Moreover, the best DRL method (PPO) yields a valid solution irrespective of the tumor location within the liver that demonstrates its robustness.", "pub_time": "2022"}
{"sha256": "40431b628c3a5767df3ee7ddf77a71c32d04dd3b832ebd720b4a3ae97a661234", "doi": "", "title": "Overcoming Interpretability and Accuracy Trade-off in Medical Imaging", "author": "", "keyword": "Interpretability, concept based explanations", "abstract": "Neural networks are considered black boxes. Deploying them into the healthcare domain poses a challenge in understanding model behavior beyond final prediction. There have been recent attempts to establish the trustworthiness of a model. Concept learning models provide insight into the model by introducing a bottleneck layer before the final prediction. They encourage interpretable insights into deep learning models by conditioning final predictions on intermediate predictions of explainable high-level concepts. However, using concept-based models causes a drop in performance which poses an accuracy vs explainability trade-off. To overcome this challenge we propose Coop-CBM, a novel concept learning model. We validate the performance of Coop-CBM on diverse dermatology and histopathology images.", "pub_time": "2023"}
{"sha256": "42cdd9d7e1a2442f7bbdaa293f12ef461960ae5ee4f7434f490806b218003dc4", "doi": "", "title": "PlanT: Explainable Planning Transformers via Object-Level Representations", "author": "Katrin Renz, Kashyp Chitta, Otniel-Bogdan Mercea, A. Sophia Koepke, Zeynep Akata, Andreas Geiger", "keyword": "Autonomous Driving, Transformers, Explainability", "abstract": "Planning an optimal route in a complex environment requires efficient reasoning about the surrounding scene. While human drivers prioritize important objects and ignore details not relevant to the decision, learning-based planners typically extract features from dense, high-dimensional grid representations containing all vehicle and road context information. In this paper, we propose PlanT, a novel approach for planning in the context of self-driving that uses a standard transformer architecture. PlanT is based on imitation learning with a compact object-level input representation. On the Longest6 benchmark for CARLA, PlanT outperforms all prior methods (matching the driving score of the expert) while being 5.3× faster than equivalent pixel-based planning baselines during inference. Combining PlanT with an off-the-shelf perception module provides a sensor-based driving system that is more than 10 points better in terms of driving score than the existing state of the art. Furthermore, we propose an evaluation protocol to quantify the ability of planners to identify relevant objects, providing insights regarding their decision-making. Our results indicate that PlanT can focus on the most relevant object in the scene, even when this object is geometrically distant. ", "pub_time": "2022"}
{"sha256": "002efb863c9bf59713d849b28ccaadba73af770bbb1b6266b1dff5808c5bee50", "doi": "", "title": "", "author": "傅伯杰", "keyword": "", "abstract": "", "pub_time": "2017"}
{"sha256": "0087f5b190eedea825beb9713642a8660dc7878dd7d48513ead200091b458c97", "doi": "", "title": "老年护理机构本土化安宁疗护模式的构建", "author": "王华萍, 朱华杰, 祝春满, 潘丹红", "keyword": "老年患者, 护理机构, 本土化, 安宁疗护, 德尔菲技术", "abstract": "背景随着社会老龄化的发展，慢病共病、失能失智患者日益增加的同时，安宁疗护的推行模式值得探讨研究。目的建立科学、规范、可行的老年护理机构安宁疗护模式。方法 通过文献检索和半结构式访谈，初步建立老年护理机构本土化安宁疗护模式函询问卷，选取上海市安宁疗护医疗、护理、行政管理及社工等领域 15 名专家进行 2 轮函询，并邀请资深安宁疗护专家进行团体访谈。结果 通过 2 轮专家函询及团体访谈，确定了老年护理机构本土化安宁疗护模式的构建，包括需具备的资源和条件、内容和流程、考核指标等 3 个一级条目及 36 个二级条目。结论 老年护理机构本土化安宁疗护模式的科学性和可靠性较好，为老年患者的生命末期优质医疗卫生服务提供了借鉴。", "pub_time": "2022"}
{"sha256": "a18e2e41a6e63dad71043bcddb16f43f0f8fc65fd5c20267ceb8cb4731b94f27", "doi": "10.13998/j.cnki.issn1002-1248.23-0741", "title": "高校图书馆服务乡村振兴的知识信息转移模型探讨", "author": "杨玲梅", "keyword": "乡村振兴, 高校图书馆, 知识信息转移模式, 农民, 知识服务", "abstract": "[目的/意义]为了更好地服务乡村振兴战略，高校图书馆挖掘已有资源潜力，服务乡村振兴的知识信息转移，以期提高农民的文化与信息素质、提高农业生产力、丰富农民精神与物质生活，值得探讨。[方法/过程]本文分析了影响农民吸收知识信息的主要原因，高校图书馆服务乡村振兴知识信息转移的变化特点，目前高校服务乡村振兴的主要路径模式及不足。为更有效做好对大多数农民的知识信息转移服务，笔者选取高校图书馆、农村图书馆、涉农企业、农民作为从高校图书馆发出到农民接收的知识信息转移的过程主体，探讨构建了两条知识信息转移的新路径模型和构建了4种知识信息转移的过程模式。[结果/结论]提出了创新高校图书馆体制机制，建设“三农”精准知识资源库与传播系统，提升乡村人员获取知识信息能力，拓宽知识信息转移渠道，缩小知识信息转移情境差距等对策，以实现高效将知识与信息转移给农民，为中国实施乡村振兴作贡献。", "pub_time": "2024"}
{"sha256": "6b42035d4da5203d950a5b7df3b53bc17439e47a64bb05c671c1f59a4d0d363a", "doi": "", "title": "专题：2030年可持续发展目标的理论、指标与实践", "author": "", "keyword": "", "abstract": "", "pub_time": "2018"}
{"sha256": "0041dbb7bdfe7390114814a1c45d304c6a229239c3f124c30c71073a4f2a006f", "doi": "10.1098/rsta.2014.0229", "title": "Gases, God and the balance of nature: a commentary on Priestley (1772) ‘Observations on different kinds of air’", "author": "John G. McEvoy", "keyword": "air(s), phlogiston, pneumatic chemistry, aerial philosopher", "abstract": "Historians of chemistry usually associate the eighteenth century with the Chemical Revolution, but it could just as readily be called ‘the century of gases’ (or ‘airs’, as they were called in the eighteenth century). In the early part of the century, the British pneumatic chemists struggled to replace the traditional notion ‘Air’, understood as an inert chemical element, with the concept of ‘air’, regarded as the third state of matter, encompassing a wide variety of chemical species. These developments constituted a necessary condition for the Chemical Revolution, which occurred in the latter part of the century. In ‘Observations’, Priestley took pneumatic chemistry to a new level, with the discovery of eight simple inorganic gases. Motivated by his belief in a benevolent God and a pious utilitarianism, Priestly explored the role of the atmosphere in the balance of nature and the politics of the state, which he linked to the movement of Rational Dissent. He styled himself an ‘aerial philosopher’ to signal the interdisciplinary nature of his inquiries, which he regarded not as a branch of ordinary chemistry, but as a mode of thought that encompassed physics, chemistry and natural theology. Priestley saw it as a source of principles and secrets of nature more extensive than that of ‘gravity itself’. This commentary was written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society.", "pub_time": "2014"}
{"sha256": "a160fe2479cb67073b5e71ce4cdff7f665993c9365ee7448dea21de9f914eb1b", "doi": "   \n10.1098/rstb.2013.0299\n \n ", "title": "How arbitrary is language?", "author": "Padraic Monaghan, Richard C. Shillcock, Morten H. Christiansen, Simon Kirby", "keyword": "language acquisition, language evolution, vocabulary, arbitrariness of the sign", "abstract": "It is a long established convention that the relationship between sounds and meanings of words is essentially arbitrary—typically the sound of a word gives no hint of its meaning. However, there are numerous reported instances of systematic sound–meaning mappings in language, and this systematicity has been claimed to be important for early language development. In a large-scale corpus analysis of English, we show that sound–meaning mappings are more systematic than would be expected by chance. Furthermore, this systematicity is more pronounced for words involved in the early stages of language acquisition and reduces in later vocabulary development. We propose that the vocabulary is structured to enable systematicity in early language learning to promote language acquisition, while also incorporating arbitrariness for later language in order to facilitate communicative expressivity and efficiency.", "pub_time": "2013"}
{"sha256": "35fe0cb8ddd686aa3421c9c131a39b4ceef6d948b57ec540fe3d9ef9ba73c65c", "doi": "10.1098/rsif.2021.0599", "title": "Transcatheter aortic valve thrombosis: a review of potential mechanisms", "author": "Vrishank Raghav, Prem Midha, Rahul Sharma, Vasilis Babaliaros, Ajit Yoganathan", "keyword": "transcatheter aortic valve, thrombosis, mechanisms", "abstract": "Transcatheter aortic valve (TAV) thrombosis has been recognized as a significant problem that sometimes occurs as early as within 30 days after valve implantation, leading to increased concerns of stroke and long-term valve durability. In this article, a critical summary of the relevant literature on identifying potential mechanisms of TAV thrombosis from the perspective of the well-known Virchow’s triad, which comprises blood flow, foreign materials and blood biochemistry, is presented. Blood flow mechanisms have been the primary focus thus far, with a general consensus on the flow mechanisms with respect to haemodynamic conditions, the influence of TAV placement and expansion and the influence of coronary flow. Less attention has been paid to the influence of blood biochemistry and foreign materials (and related endothelial damage), with little consensus among studies with regards to platelet and/or microparticle levels post-TAV implantation. Finally, we discuss the future outlook for research with unanswered scientific questions.", "pub_time": "2021"}
{"sha256": "6b9663579b28579da48aba782d7d395ff6a11a0ee757a50e0d6b375c0ec179ae", "doi": "10.1098/rsos.160603", "title": "The relationship between health and mating success in humans", "author": "Yong Zhi Foo, Leigh W. Simmons, Gillian Rhodes", "keyword": "health, humans, mating success, sexual selection", "abstract": "Health has been claimed to play an important role in human sexual selection, especially in terms of mate choice. Our preferences for attractive individuals are said to represent evolved adaptations for finding high-quality, healthy mates. If this is true, then we expect health to predict mating success in humans. We tested this hypothesis using several important physiological indicators of health, including immune function, oxidative stress and semen quality, and self-reported measures of sexual behaviour that contribute to mating success. In contrast to our hypothesis, we did not find a relationship between the physiological measures of health and sexual behaviour. Our results provide little support for claims that health, at least the health measures we used, increases mating success in relatively healthy humans.", "pub_time": "2016"}
{"sha256": "35c380ce7c1fe7e366d44a6de58e35900b5777b372735459cc20c92c0a2f28a6", "doi": "", "title": "Nash谈判解预测能力的实验证据", "author": "李建标, 李晓义", "keyword": "双边讨价还价,Nash谈判解,第4公理", "abstract": "讨价还价是人们最基本的交易规则之一。在非结构化的讨价还价中，Nash 谈判解具有重要的预测意义，但之前的实验研究表明，Nash 谈判解的第 4 公理，即效用线性变换无关性公理，并没有得到实验结果支持。本文的工资分配谈判实验表明，即使在完全信息条件下，第 4 公理仍然是不可拒绝的，即 Nash 谈判解具有完全的预测能力。", "pub_time": "2006"}
{"sha256": "001086dd62b571584ca7cfa8a7b0fc77ef41e52749cfe7bfc33c2684b358d777", "doi": "", "title": "美国关于医疗卫生费用的理论研究与政策争论", "author": "张奇林", "keyword": "美国, 医疗卫生费用, 理论研究, 政策争论", "abstract": "如何认识和控制医疗卫生费用的上涨 ,长期以来一直是美国理论界研究和争论的一个焦点问题。技术进步是推动费用上涨最重要的因素。而医疗卫生费用的快速上涨既会 损害公平 ,也会损害效率。政府管制与市场竞争是控制费用的两种理念与方法。但是 ,在美国 这样一个利益分化、文化多元、政治分权的社会 ,要想在医疗卫生费用问题上 ,特别是在费用控制问题上达成某种共识 ,尚有很长的路要走。", "pub_time": "2007"}
{"sha256": "a12dc602273ed7749161309466fe322a272792a83107b3fc33f198dac4b06c4d", "doi": "", "title": "论冯契的广义认识论", "author": "杨国荣", "keyword": "广义认识论,冯契", "abstract": "冯契先生既没有将哲学的演进视为从本体论向狭义认识论的单一衍化，也不赞同将认识论作为克服的对象。以广义认识论为视域，冯契先生将知识与智慧的统一引入认识论，这是对何为哲学与哲学何为一元哲学问题的澄明。", "pub_time": "2006"}
{"sha256": "a14751a0b5e4a56928d6958605b8980a1af1a359b2e1026da24abc9049c5cac4", "doi": "", "title": "自我效能干预与运动愉悦感：年龄差异和相关因素分析", "author": "胡亮,吕佳颖,杨涛,朱燕燕", "keyword": "运动愉悦感, 自我效能, 社会认知理论, 健康促进", "abstract": "对自我效能进行干预可以影响人们对运动的情感体验，但在我国还没有研究通过自我效能干预的方式对运动—自我效能—愉悦感之间关系的年龄差异和影响运动愉悦感的其他社会心理因素进行深入分析。本研究以 56 名老年人、33 名大学生、和 44 名初中生为研究对象，分别将其随机分为高、低自我效能干预组，分别在运动测试后给予积极和消极两种相反的运动能力反馈。结果发现：1）运动能力反馈在老年人和大学生中都未能产生自我效能变化的组间差异；2）高自我效能干预组与低自我效能干预组的初中生相比，自我效能显著提高，对于运动感到更为愉悦；3）老年人的运动愉悦感最高，大学生次之，中学生最低；4）自我效能的改变、特质焦虑和年龄是和运动愉悦感显著相关的因素，这三个指标可以解释运动愉悦感变异的 43%。本研究验证了自我效能干预与愉悦感之间的密切联系，讨论了如何通过调控自我效能，提高人们参与运动的积极体验，更好地进行锻炼和健康促进。", "pub_time": "2011"}
{"sha256": "d84a7489d06befe4491e11d711d5ad075a69ebb3e8df166862b4eeeeb3943eae", "doi": "", "title": "经济增长、电力消费与环境污染关系研究——来自珠江三角洲的证据", "author": "张华, 朱泯静", "keyword": "电力消费, 经济增长, 环境污染, 面板VAR, 面板协整检验", "abstract": "本文主要基于珠江三角洲9个城市1996-2011年的面板数据，运用IPS、LLC、Fisher以及individualADF单位根检验、Westerlund多变量面板协整检验、面板误差修正模型、面板脉冲响应分析与面板格兰杰因果分析对经济增长、电力消费与环境污染三者的关系进行分析。实证结果表明：第一，三个变量均为非平稳序列，且存在长期稳定的协整关系，当三者的均衡关系在短期内偏离长期均衡时，将以57.16%的调整速度将其调整至均衡；第二，电力消费与经济增长存在双向格兰杰因果关系，而电力消费、经济增长分别对环境污染存在单向格兰杰因果关系；第三，珠三角地区9个城市环境污染对GDP的弹性系数排前四位的分别是：佛山、肇庆、惠州、广州，而排在最后两位的是中山和深圳。", "pub_time": "2014"}
{"sha256": "a239d27ca49faa6df83cfd4955b7e44b5e0e7bcdd7ce23828a908a505d29718a", "doi": "", "title": "我国公共图书馆集成管理系统的调查与分析", "author": "刘鎏", "keyword": "公共图书馆, 集成管理系统, 图书馆管理", "abstract": "基于调查结果的分析，本文对国内公共图书馆使用或设计图书馆集成管理系统提出了若干建议，包括实现 系统的高可用性、加强集群化管理能力、应用图书馆开源软件和构建基于云计算理念的图书馆集成管理系统。", "pub_time": ""}
{"sha256": "000c5f2a21ad62164196968ed6b3458e7487005cc436619df541bf49c0dcfafb", "doi": "", "title": "浅谈我国《宪法》中的社会保障思想", "author": "刘永涛", "keyword": "04年宪法,社会保障,效率,公平", "abstract": "我国现行宪法在82年宪法的基础上，历经了四次修正。在 04年宪法中，明确提出了“国家建立健全同经济发展水平相适应的社会保障制度。”本文将从宪法的第十四条第三款、宪法第四十四条以及第四十五条入手深入挖掘其中体现的社会保障思想，希望能够为我国社会保障法律体系的建设提供一些依据。", "pub_time": ""}
{"sha256": "6b4f30b08167c77227b8f8bbb0efd327e6a16a424b640d7db0b5dafb5c2d740a", "doi": "", "title": "PRODUCTION AND DECAY PROCESSES INVOLVING VECTOR MESONS", "author": "William G. Wagner", "keyword": "", "abstract": "Many resonances in the scattering of fundamental particles have been recently discovered, which may be interpreted in terms of unstable particles. One of these may be a vector meson coupled to the hypercharge current, whose decay rates are calculated. Predictions are given for the total decay rate, and branching ratios, in terms of $\\gamma_{H}^{2}/4\\pi$, the strength of the hypercharge coupling. Another resonance may be correlated with the missing member, $\\chi$, of an octet of pseudoscalar mesons in the \"Eightfold Way\" of Gell-Mann; a reasonable estimate of the branching ratio $\\Gamma(\\chi \\to 2\\gamma)/\\Gamma(\\chi \\to \\pi^{-} + \\pi^{+} + \\gamma)$ is obtained. A resonance in the K-$\\pi$ system may be Gell-Mann's M-meson; the role of M in the associated production of $\\Lambda$'s by pions and in $\\Lambda$ production by $\\bar{K}$'s is examined. The existence of a new class of asymptotic cross section equalities, which are generalizations of the Pomeranchuk relations, is demonstrated. The pion plus lepton decays of the kaon are considered, and it is shown that they cannot be determined by an intermediate M-meson. The fraction of $\\rho$'s, the vector mesons that appear as a resonance in the two-pion system, that decay into four pions is estimated to be less than 1%.\n", "pub_time": "1962"}
{"sha256": "35a95db366f814220de8d625dbcad2ec289e47d6275616d7e01e6ea1a59fba38", "doi": "", "title": "CHARACTERIZATION OF MOLECULAR EVENTS IN THE PATHOGENESIS AND DEVELOPMENT OF BREAST CANCER", "author": "Susan Jane Done", "keyword": "", "abstract": "Breast cancer may arise from a progressive accumulation of genetic alterations. The complete spectrum of these and the stages at which they occur is not known. Epidemiological evidence links mammary epithelial hyperplasias and carcinoma in-situ (so called \"early lesions\") with invasive breast cancer. However, whether these lesions represent direct precursors or are merely markers of increased risk is unclear. This thesis is based on the hypothesis that the characterization of the mutational status of genes, such as p53, and loss of heterozygosity (LOH) status of chromosomal regions, in normal tissue, pre-malignant lesions, pre-invasive and invasive breast cancer will yield novel insights into the molecular etiology of breast tumorigenesis.\nA LOH study of the chromosomal region 11q23 in axillary lymph node-negative (ANN) breast cancers found that loss at this location was associated with a higher rate of estrogen receptor (ER) positivity. The onset of LOH in \"early lesions\" surrounding invasive breast cancer was found to be variable between loci, between cases and within cases. Study of a group of synchronous primary breast cancers revealed a markedly lower rate of LOH when compared to a group of solitary ANN tumours.\nStudy of the tumour suppressor gene p53 showed that when a mutation was present in an invasive breast cancer the same mutation could also be found in all surrounding areas of DCIS but not in any areas of epithelial hyperplasia or normal breast tissue. The spectrum of mutations that could be recognized by a widely used anti-p53 antibody (DO7 clone, Novocastra) was characterized. This knowledge was used to screen a panel of new DCIS cases by immunohistochemistry prior to mutational analysis, aiding detection of p53 mutations in DCIS not associated with invasive disease.\nPatterns of LOH in early lesions and synchronous primary tumours is suggestive of an overlapping field effect leading to an hierarchical distribution of genetic alterations with p53 mutation occurring prior to the onset of invasion. Further characterization of these fields could provide improved patient assessment and management. Knowledge of the early genetic steps in breast cancer tumourigenesis may result in new approaches to diagnosis and disease prevention.", "pub_time": "2000"}
{"sha256": "35b73cf9af83002750bd1e43996f36afe1c08ceb1f20ca83cb9c954b9d02f220", "doi": "", "title": "THE OBSERVATION AND CATEGORIZATION OF LOAD AND POWER FACTORS IN CANDIDATES FOR OPEN-HEART SURGERY", "author": "Helen M. Ference, B.S.", "keyword": "", "abstract": "", "pub_time": "1972"}
{"sha256": "35b8a14af07e436d9168bf95550611aac9e5f4b8211931c376db394cc02875be", "doi": "", "title": "COMPUTATIONAL GENOMICS TO CHARACTERIZE THE DISTRIBUTION, DIVERSITY, AND DRUG RESISTANCE OF FUNGAL PATHOGENS", "author": "Kizee A. Etienne", "keyword": "", "abstract": "", "pub_time": "2022"}
{"sha256": "35bdd8a0351e948d5734c3abbc09f03421066424f96a06f627db552b2ec7c5d5", "doi": "", "title": "An Ultra-high Throughput Droplet Microfluidics Platform for the Generation and Screening of SICLOPPS Cyclic Peptide Libraries In Vitro", "author": "Catrin Sohrabi", "keyword": "", "abstract": "In vitro compartmentalisation (IVC) has emerged as an attractive cell-free based technological platform for the miniaturisation and mass parallelisation of biochemical reactions in microscopic aqueous-in-oil emulsion droplets. In implementing this emulsion-based technology, this thesis describes the development of an ultra-high throughput drug discovery platform for the IVC of split-intein based SICLOPPS cyclic peptide libraries in femtolitre-sized aqueous compartments for the rapid identification of novel protein-protein interaction (PPI) inhibitors. In utilising the unique thermoresponsive properties of agarose, the efficient encapsulation and isothermally-mediated pre-DNA amplification of single plasmid DNA copies in approximately 113 fL agarose-in-oil femtodroplets is performed, yielding porous agarose beads comprising highly condensed concentrations of DNA. Solidified beads are thereafter employed in in vitro transcription/translation (IVTT) of the encoded cyclic peptide genes alongside a pETDuet-1 co-encoded Aβ42-GFP fusion assay, whereby the aggregation state of the Aβ42 Alzheimer's disease peptide is linked to the correct folding of GFP, by co-encapsulating individual agarose particles alongside PURExpress IVTT machinery. Fluorescence-activated cell sorting (FACS) is subsequently used to demonstrate the feasibility through which beads exhibiting increased levels of GFP fluorescence, and thus of those comprising cyclic peptides with the ability to modulate the aggregation state of Aβ42, may be efficiently and selectively recovered at rates exceeding 107 per hour. Collectively, the isolation and recovery of a diverse Npu SICLOPPS cyclic peptide library via FACS is achieved, demonstrating the value and widespread utility of the droplet microfluidics screening platform as described herein for the prompt discovery of novel cyclic peptide inhibitors of challenging PPIs.", "pub_time": "2018"}
{"sha256": "a0efbb60731c2ef4c235184a8d5dc3f824fbf6a4ac4c65cdf1ef3f800de3204d", "doi": "", "title": "Strain Heterogeneity in the Anterior Cruciate Ligament and Constitutive Modeling with Full-Field Methods", "author": "Callan M. Luetkemeyer", "keyword": "", "abstract": "Anterior cruciate ligament (ACL) injury rates are rising, particularly for women and young people. These injuries are debilitative; they typically require surgical reconstruction and lead to osteoarthritis within ten years. Still, there is little consensus about what puts someone at risk for an ACL injury, and this knowledge is critical to the development of injury prevention strategies. Finite element models provide an effective platform for systemically determining the effect of proposed injury risk factors on ACL strain concentrations, and thus, determining whether they predispose an individual to injury. However, the accuracy of a finite element model relies on the accuracy of the material models used in its construction.\nInitially, I examined how the shape of the ligament-bone attachment (enthesis) might affect injury risk. Two factors were found to increase effective strain concentrations: more acute attachment angles and more concave enthesis shapes, both of which are more common in women. However, I also discovered that enthesis shape significantly affects the macroscopic (global) mechanical response of the model ligament. As such, I concluded that enthesis geometry (and the deformation heterogeneity it creates) would need to be considered in the construction of material models.\nI also explored the effect of collagen fiber splay (material direction heterogeneity) on the macroscopic mechanical response of the ACL bundles and the patellar tendon (PT), a commonly used graft for ACL reconstruction. Using analytical, computational, and experimental approaches, results clearly demonstrate that splay geometry significantly affects the macroscopic mechanical response of ligaments. Since material properties are, by definition, independent of geometry, this indicates fiber splay is a structural property that prevents the identification of true material properties with standard modeling techniques.\nHence, in the finale of this work, I used displacement-encoded magnetic resonance maging (MRI) to measure full-volume deformation fields of the ovine PT and both ACL bundles under tension. I then employed the virtual fields method (VFM) – a full-field inverse method – to calibrate material models with this data, accounting for strain heterogeneity, material direction heterogeneity (fiber splay), and enthesis shape. Most constitutive parameters were consistent among all specimen groups, demonstrating the universality of ligament material constituents. A material parameter describing the degree of anisotropy, or collagen fiber alignment, however, showed statistically significant differences between groups. It indicated that collagen fibers in the anteromedial (AM) bundle of the ACL were significantly more aligned than those in the posterolateral (PL), which is congruent with optical measurements. My work demonstrates that (when strain heterogeneity and structural properties are accounted for) ligament material microstructure is detectable with measures of mechanical function.", "pub_time": "2020"}
{"sha256": "35ca5f9b64a975af52da83494f68903c69a2540bb193b5f1df0e4d71a87c91d5", "doi": "", "title": "COUPLING AGENT EFFECTS ON THE INTERFACIAL ADHESION IN A SHEATH/CORE TYPE BICOMPONENT FIBER", "author": "Jian-xing Li", "keyword": "", "abstract": "Rayon/nylon-6 and rayon/polypropylene bicomponent S/C fibers were produced by a coating process. The purpose of this research is to promote the interfacial adhesion between skin and core materials to improve the durability of the coating.\nFiber pretreatment techniques were used to improve the surface properties of fiber before it was coated in order to promote the interfacial adhesion of the S/C fiber. Water was used to remove the spin finishes on the synthetic fiber. Coupling agent solutions were used to pretreat the fibers. Both pretreatment techniques were sufficient to promote the interfacial adhesion at the certain conditions. The effects of the pretreatment on both adhesion and tensile properties of the S/C fibers were determined.", "pub_time": "1989"}
{"sha256": "0001eed7a28138b814178a5588cd007065517a2bce4f48d2c144a92e567e1275", "doi": "", "title": "DEVELOPING A NEW INTERATOMIC POTENTIAL AND ATOMISTIC STUDY OF NiTiHf", "author": "Saeed Ataollahi", "keyword": "", "abstract": "With the growing demand for high-temperature shape memory alloys (HTSMAs), NiTi-based HTSMAs have gained more attention for implementation in applications at elevated temperatures. Among NiTi-based alloys, NiTiHf has shown to have great potential, by having high transformation temperatures, lower preparation cost and good thermal stability. However, until today, most studies conducted on NiTiHf have focused on a limited range of compositions due to the difficulties and high cost of the experimental studies. Therefore, there exists a lack of comprehensive research on the thermo-mechanical behavior of these HTSMAs. Computational simulations are a very cost-effective and feasible approach for addressing this shortcoming. Among computational methods, molecular dynamics (MD) simulation as an atomistic method offers comprehensive means to explore microstructural phenomena that govern the behavior of material. An essential requirement for performing MD simulations is interatomic potential which serves as the constitutive equations of MD and determine the forces and interactions between atoms. Since no applicable interatomic potential has been developed for NiTiHf, there has not been any progress in MD studies on NiTiHf alloys. Therefore, in this study, a Second Nearest-Neighbor Modified Embedded Atom Method (2NN MEAM) interatomic potential has been developed to accurately represent the NiTiHf ternary system. Initially, the parameters of constituent unary and binary potentials were calibrated by fitting their reproduced results of physical properties to DFT results. Then, the final ternary MEAM potential was checked for reliability and transferability by performing MD simulations. The results showed that the developed potential can accurately capture temperature-induced and stress-induced martensitic phase transformation in NiTiHf. In addition, the lattice parameters and formation energy of different compositions of NiTiHf were obtained and compared with experimental and DFT (Density Functional Theory) results showing a good agreement. Furthermore, using the developed MEAM potential, MD simulations were conducted to analyze the influence of precipitates on the superelasticity and shape memory effect of NiTiHf alloy. The results showed that in the presence of H-phase precipitates, the transformation temperatures increase. In addition, the thermal cycling of NiTiHf under constant stress was simulated and it was found that reducing the temperature rate results in a narrower thermal hysteresis.", "pub_time": "2023"}
{"sha256": "d738db6d781c0024372861506bc3860dc51d2f5b3fc5045d79abea981d516961", "doi": "", "title": "“我们时代的鲜活记录”", "author": "多罗西娅·兰格", "keyword": "", "abstract": "去看见生活；去看见世界；去目击重大事件；去看穷困者的面庞，也去看骄傲者的身姿；去认识奇怪的事物——机器、军队、大众、丛林里或月球上的阴影；去见证人类的杰作——绘画、高塔、新发现；去眺望千万里之外的事物，去窥见隐蔽在墙后边、房间里的东西，去发现即将到来的危险；去欣赏拥有丈夫和孩子热爱的女人；在观看中发现并获得愉悦，在观看中收获惊奇，在观看中获得教导；所以现在，看和被看会成为一半人的愿景和新期待。", "pub_time": "2014"}
{"sha256": "d73917739a4e65324063e50dbfe87574bd0009d483ef617a27f9f11e22b7f5f0", "doi": "", "title": "创造力与精神障碍：实证心理学的探讨", "author": "邹泓, 曾荣, 王娟", "keyword": "创造力, 精神障碍, 双相谱系障碍, 精神分裂谱系障碍", "abstract": "关于“疯狂天才”的讨论由来已久，但以实证手段探讨创造力与精神障碍之间的关系始于2O世纪80年代末。通过对创造力与双相谱系障碍、精神分裂谱系障碍以及其他几种类型精神障碍之间相关研究的梳理，可以认为虽没有足够证据表明精神疾患可直接带来个体较高的创造性，但两者之间(尤其是在文学和艺术领域中)的确存在一定程度的共生现象。适度的双相障碍症状和轻微的精神分裂症谱系人格特质与创造力有一定关联，而精神分裂症和严重的双相障碍则会损害个体的创造力。对于创造力和精神障碍存在的这一共生现象，文章从认知加工、遗传与脑机制、人格特质及发展背景几个角度回顾了相应的理论解释和研究证据。", "pub_time": "2015"}
{"sha256": "d7391d816c5b46f33e7d3b83f18c2f290f5a5a4fb9fea3e66a7aaaaa02867dab", "doi": "10.16457/j.cnki.hbhjjlw.2023.10.024", "title": "山东省出口贸易状况分析", "author": "杨全坤, 燕敬宇, 周金", "keyword": "", "abstract": "", "pub_time": "2023"}
{"sha256": "d7394f33ab4317ce90d566cf5e0ccf4b3b01a4430990a0d379f32dab58b9cff9", "doi": "", "title": "国家发展改革委举行12月份定时定主题新闻发布会介绍宏观经济情况并回应热点问题", "author": "刘保林", "keyword": "", "abstract": "2017年12月18日上午，国家发展改革委举行12月份定时定主题新闻发布会。政研室副主任、委新闻发言人孟玮出席发布会，介绍电力运行、投资管理、价格运行和监管、经济体制改革、社会信用体系建设、能耗总量和强度“双控”目标完成情况及最新出台的重大政策文件等方面情况，并就保障天然气稳定供应、民营企业境外投资经营行为规范、促进石化产业绿色发展、京津冀民航协同发展、鼓励民间资本参与PPP项目、加强产权保护、应对气候变化等相关问题，回答了与会记者提问。70余家境内外新闻媒体约100名记者参加了本场发布会。", "pub_time": "2017"}
{"sha256": "d739d4e3435953681e364fac11fb0f57a715ac9ae0f57bb7f3bf212c1be298fa", "doi": "", "title": "所有磁铁的磁力都一样吗？", "author": "", "keyword": "", "abstract": "", "pub_time": ""}
{"sha256": "d73a18e8337e94a4742829b761448406f8a00739356d608d5307ca9f24e200a5", "doi": "", "title": "广东省机关事业单位人才发展现状与人才交流机制探析", "author": "郭商羿", "keyword": "机关事业单位,省直事业单位,人才发展,人才交流", "abstract": "广东省的人才发展工作在稳岗扩就业、社保改革、创新活力、技能培养、劳动关系保障等领域取得了一定成就，但也存在着人才分布失衡、人才外流、投入机制不完善等问题。机关事业单位作为关键人才载体，其人才交流机制建设对推进发达地区与欠发达地区的人才互联、互通、互换，引导人才资源合理有序流动具有积极意义，对建设粤港澳大湾区高水平人才高地具有引导作用。构建广东省人才协调发展新格局，应打造广东省人才发展“一盘棋”，梳理各地区人才种类与数量，赋予省级人力资源合理统调的权限，构建具有广东特色的机关事业单位人才储备库；促进互联互通，打造广域线上交流平台；打破专业壁垒，优化内部人员选拔机制。", "pub_time": "2023"}
{"sha256": "d73a3bb2411e519c080176b771b9751a0b478e338a9d45ec5941145b3fdf88a7", "doi": "", "title": "网络犯罪的防范策略", "author": "杨仕梅", "keyword": "网络犯罪,防范策略,犯罪立法,国际合作", "abstract": "网络犯罪是伴随着计算机技术的发展而产生的一种新的犯罪形式，由于其具有很强的隐蔽性，且犯罪手段比较先进，因而较难防控，给社会造成了极大的危害。防范网络犯罪严重的破坏性，应完善立法体系，加强防范网络犯罪的法律宣传力度，加强计算机防范设施和侦查技术设施建设，并加强国际合作及对国际犯罪的侦查力度。", "pub_time": "2014"}
{"sha256": "d73a4209f989fbd1f61ecf820021fcd3bf165d91fc1d2ff9aa8799ebdaebd7d2", "doi": "10.3963/j.issn.1006-8864.2014.6.017", "title": "区域绿色循环低碳交通运输发展评价", "author": "王利军, 李英杰, 陈强", "keyword": "交通运输, 绿色, 低碳, PSR, 区域, 指数", "abstract": "绿色循环低碳交通运输发展包含交通运输的绿色发展、循环发展和低碳发展内涵，这里的“发展”强调的是量的选择，绿色、循环、低碳则是质的要求和对发展方式、量的具体约束，本质是发展模式的转换，特征是“低消耗、低排放、低污染”的“三低”和“高循环、高碳汇、高效率”的“三高”，核心是提高碳生产力。因此，对绿色循环低碳交通运输发展评价需考虑其现状、影响结果、因果关系、发展机理等方面综合评价。联合国可持续发展委员会提出的 PSR（pressure-state-response 即“压力-状态-响应”）模型。欧洲环境局（EEA）综合 PSR 模型和 DSR（drive-state-response 即“驱动力-状态-响应”）模型的优点建立的 DPSIR（即“驱动力-压力-状态-影响-响应”）模型，能有效反映人类活动与资源环境之间的相互作用关系机理，并将复杂的因素作用过程简化，评价指标体系予以清晰，且能连续监测各指标间的反馈机制，具有系统性和综合性等特点，在可持续发展和环境影响评价中得到广泛应用。因此，笔者从有效性出发，试图应用 PSR 模型构建指标体系，对区域绿色循环低碳交通运输发展作出有效评价。", "pub_time": "2014"}
{"sha256": "d7b89215a38df747f0b4b950a5ba56eba6420c1ae9beea1759349d7cde4b5a34", "doi": "10.1108/JMLC-05-2021-0052", "title": "International commercial arbitrator addressing money laundering sua sponte", "author": "Todor Kolarov", "keyword": "Money laundering, International commercial arbitration, 2012 Recommendations of the Financial Action Task Force", "abstract": "Purpose – The purpose of this paper is to evaluate the existing legal basis, and its practical application, of an arbitrator’s competence to raise on her own initiative money laundering issues.\nDesign/methodology/approach – The research focusses on presenting the essence of the problem through evaluation of the legal basis for the arbitrators to raise money laundering concerns on their own initiative and the examples of so being done in international commercial arbitration.\nFindings – This paper concludes that arbitrators do not presently have a solid legal basis that authorises them to actsua sponte against money laundering. \nOriginality/value – The originality and value of this paper lies in its emphasis on theoretical and practical issues related to money laundering in international commercial arbitration. It argues in favour of an explicit recommendation to be incorporated in the 2012 Recommendations of the Financial Action Task Force (FATF) that international commercial arbitrators address money laundering on their own initiative.", "pub_time": "2022"}
{"sha256": "d7b8f22a4b603dc6492dc95449aceae90eac5253ae2eaccefaadd91ca527a486", "doi": "", "title": "青蒿素 B 的立体选择合成", "author": "许吉祥, 朱杰, 周维善", "keyword": "", "abstract": "青蒿素 B 是从中药青蒿中分离到的另一个倍半萜内酯。它的结构早已被测定。最近已见其异构体合成的报道。本文报道首次合成天然青蒿素 B 的结果。", "pub_time": "1982"}
{"sha256": "d7b918587a5c8bc5f930bab72ae19972cfb2fb65336a18e00bc29d2c1078a3cd", "doi": "", "title": "DEVELOPMENT OF TWO-GROUP INTERFACIAL AREA TRANSPORT EQUATION FOR CONFINED FLOW - I: MODELING OF BUBBLE INTERACTtONS", "author": "Xiaodong Sun, Seungjin Kim, Mamoru Ishii, Stephen G. Beus", "keyword": "Interfacial area, Two-group transport equation, Bubble interaction mechanisms, Bubbly flow, Churn-turbulent flow, Two-fluid model", "abstract": "To provide a dynamic and mechanistic constitutive model for the interfacial area concentration in the two-fluid model, a two-group interfacial area transport equation is developed for confined two-phase flows in this series of papers. This paper presents the modeling of bubble interaction mechanisms in the two-group interfacial area transport equation for confined gas-liquid two-phase flow. The transport equation is applicable to bubbly, cap-turbulent, and churn-turbulent flow regimes.\nIn the two-group interfacial area transport equation, bubbles are categorized into two groups: spherical/distorted bubbles as Group 1 and cap/slug/churn-turbulent bubbles as Group 2. Thus, two sets of equations are used to describe the generation and destruction rates of bubble number density, void fraction, and interfacial area concentration for the two groups of bubbles due to bubble expansion and compression, coalescence and disintegration, and phase change. Five major bubble interaction mechanisms are identified for the gas-liquid two-phase flow of interest, such as, bubble coalescence as a result of random collision driven by turbulent eddies, the entrainment of the bubbles following in the wake of preceding bubbles, bubble break-up due to turbulent impact and surface instability for large bubbles, and small bubble shearing-off at the rim of large bubbles. These interaction mechanisms are analytically modeled as the source/sink terms for the transport equations based on certain assumptions for the confined flow. The models include both intra-group (within a certain group) and inter-group (between two groups) bubble interactions.\nA complete set of models close the two-group interfacial area transport equation, which has embedded the mechanisms of the flow regime transition. The comparisons of the prediction by the one-dimensional two-group interfacial area transport equation with experimental data are presented in the second paper of this series.", "pub_time": ""}
{"sha256": "d7ba283c81153953fe66d41b7d0dd32bce01289e2fbab3937d806f6d0fa251d2", "doi": "10.1016/j.apacoust.2022.108976", "title": "Crossing the linguistic causeway: A binational approach for translating soundscape attributes to Bahasa Melayu", "author": "Bhan Lam, Julia Chieng, Karn N. Watcharasupat, Kenneth Ooi, Zhen-Ting Ong, Joo Young Hong, Woon-Seng Gan", "keyword": "Soundscapes, Translation, Psychoacoustics, Bahasa Melayu, Circumplex", "abstract": "Translation of perceptual descriptors such as the perceived affective quality attributes in the soundscape standard (ISO/TS 12913–2:2018) is an inherently intricate task, especially if the target language is used in multiple countries. Despite geographical proximity and a shared language of Bahasa Melayu (Standard Malay), differences in culture and language education policies between Singapore and Malaysia could invoke peculiarities in the affective appraisal of sounds. To generate provisional translations of the eight perceived affective attributes — eventful, vibrant, pleasant, calm, uneventful, monotonous, annoying, and chaotic — into Bahasa Melayu that is applicable in both Singapore and Malaysia, a binational expertled approach supplemented by a quantitative evaluation framework was adopted. A set of preliminary translation candidates were developed via a four-stage process, firstly by a qualified translator, which was then vetted by linguistics experts, followed by examination via an experiential evaluation, and finally reviewed by the core research team. A total of 66 participants were then recruited cross-nationally to quantitatively evaluate the preliminary translation candidates. Of the eight attributes, cross-national differences were observed only in the translation of annoying. For instance, menjengkelkan was found to be significantly less understood in Singapore than in Malaysia, as well as less understandable than membingitkan within Singapore. Results of the quantitative evaluation also revealed the imperfect nature of foreign language translations for perceptual descriptors, which suggests a possibility for exploring corrective measures.", "pub_time": "2022"}
{"sha256": "d7ba83b71b4ea145cbf05bbc6de25579a8cde7702bc3c464508a4ee8dee504d2", "doi": "", "title": "農地制度の変化に伴う都市農地の利用に関する現状分析東京都町田市の農地パンクを事例としてー", "author": "竹島久美子", "keyword": "urban fringe farmland, farmland liquidation, the (former) Farmland Bank", "abstract": "The objective of this analysis is to examine a measure for effective utilization of urban fringe farmland through an agricultural land institutional change. The change extended a measure decided by zoning. We focused on Machida-city in Tokyo, which created a plan called the (former) Farmland Bank for farmland liquidation based on that institutional change. The programme works as an intermediation mechanism between farmland owners and farmers who want to rent farmland either as existing farmers and new entrants. In addition to this programme, Abandoned Farmland Programmes promoted agricultural land lease and resolved the problem of abandoned farmland.", "pub_time": "2015"}
{"sha256": "d7bac04a0e9e29ad294ec9afedfcabb63a4a7250841143d8db45adc38317228c", "doi": "", "title": "闭待ち行列ネットワークによる機能分散形 FMS の最適設計", "author": "長沢啓行,西山徳幸", "keyword": "", "abstract": "フ レ キ シ ブル 製造シ ス テ ム （FMS ）の 設 備 設 計 に お い て は ，ス テ ーシ ョ ン 数 ，機械 台数構成，シ ス テ ム 内パ レ ッ ト 数 ，負荷 （工 具）配分 を同時に決定 しな ければな らな い ．これ を シ ミ ュ レ ーシ ョ ン で行 う に は ，代替 案の 作成 とシ ミ ュ レ ーシ ョ ン に膨 大 な 労力 を要 し ，得 ら れ た 設 計 案 の 最適 性 も保 証 さ れ な い ．そ こ で ，閉待 ち 行列ネ ッ トワ ーク （CQN ） で FMS を モ デル 化 し ，CQN モ デル の 解析 結果 を駆使 して 最適設 計 を行 う試 み が な さ れ ，負荷均 等配 分 の場 合 に 対 して は 最適設 計法が 提案 さ れ て い る ．本研究 で は ，こ の 負荷 均等配 分 の 制約 を除去 し，機械台数構成や 負荷配分 を も意思決 定の 対 象 と した ，よ り．一般的な機能分散型 FMS に 対し ，最適設計 法 を提案 す る ．い くつ か の 数 値例 を解 く こ と に よ り，提 案 ア ル ゴ リズ ム で は 最適解が ご く短 時問 に 得 られ る こ と，負荷均等配分 に よる解が 最適解 と一致す る 場 合が 多 く，一致 しない 場 合 で も精度の 高 い 近似解に な る こ と を明 らか に す る ．", "pub_time": "1996"}
{"sha256": "d7bb21b6fcc25f3b139bc32c623041b0effbf1ef35b10ae36fabebe585329334", "doi": "10.1016/j.cej.2021.132829", "title": "On-site H₂O₂ electro-generation process combined with ultraviolet: A promising approach for odorous compounds purification in drinking water system", "author": "Yiying Zhao, Ning Deng, Zhiheng Fan, Zhong-Ting Hu, Lili Fan, Jizhi Zhou, Xin Huang", "keyword": "Hydrogen peroxide On-site generation Advanced oxidation process Taste and odor (T&O) compounds Trichloroanisoles", "abstract": "The on-site generation of hydrogen peroxide (H2O2) attracts much attention for advanced oxidation processes (AOPs) in water treatment. In this work, we reported a novel on-site H2O2 generation reactor combined with ultraviolet (UV) for taste and odor (T&O) compounds removal in drinking water purification systems. The reactor is equipped with a gas diffusion electrode (GDE) accompanied by a proton-conducting solid electrolyte. In this reactor, GDE is used to improve the oxygen transfer efficiency. The porous solid electrolyte is selected for the proton and electron conduction instead of an electrolyte solution, which is crucial for producing pure H2O2 solution. The production rate and concentration of H2O2 can be controlled through adjusting the applied current efficiency and the flow rate of deionized water in a solid chamber. Meanwhile, this system exhibits long-term stability during a continuous operation for 96 h. For the application of the system, the single-cell was assembled into cell stacks, which improved the H2O2 concentration from 780.9 to 2301.3mg⋅L−1, along with the energy consumption reduced from 23.81 to 6.67kWh⋅kg−1 under the applied current density of 30 mA⋅cm−2. To evaluate the water purification performance of this system, the oxidation degradation of 2,4,6-trichloroanisoles (TCA) was conducted using the on-site H2O2 generation process under both static and dynamic flow conditions combined with UV light. The degradation rate of TCA was >95% with its initial concentration of 1μg⋅L−1 under the hydraulic retention time from 10 to 40 min−1 and H2O2 dosage from 10 to 100mg⋅L−1. Meanwhile, almost no residual H2O2 was detected after the degradation process. This study proposed a promising device for drinking water purification", "pub_time": "2022"}
{"sha256": "3a2ee64048a5c4d4c654be754a8c07fb07ded4d1947066c29045db3548ae13fd", "doi": "", "title": "Hostile Environment?", "author": "Perry A. Zirkel", "keyword": "", "abstract": "", "pub_time": "1998"}
{"sha256": "ade438279825c03a0d06983f2bee5a64bb7cc4dd5810b52a4df67f564fda480c", "doi": "10.1002/anie.202002984", "title": "   \nAtomically Dispersed Ni(I) on Alloy-Encapsulated Nitrogen-Doped Carbon Nanotube Array for High-Performance Electrochemical CO2 Reduction Reaction\n \n ", "author": "   \nTianyu Zhang, Xu Han, Hongbin Yang, Ajuan Han, Enyuan Hu, Yaping Li, Xiaoxiang Yang, Lei Wang, Junfeng Liu, Bin Liu\n \n ", "keyword": "", "abstract": "Single-atom catalysts (SACs) show great promises for electrochemical CO2 reduction reaction (CRR), but the low density of active sites and the poor electrical conduction and mass transport of the single-atom electrode greatly limit their apparent performances. In this study, we have studied the catalytic performance of a single-atom structured and functional single-atom electrode with high density of exposed active sites and promoted electrical conductivity and mass transport. Herein, we prepared a nickel single-atom electrode consisting of isolated, high-density and low-valent nickel(t) sites anchored on the self-standing N-doped carbon nanotube array with a thickness of 0.32nm. The electrochemical performance of the combination of single-atom nickel(t) sites and self-standing array structure gives rise to an excellent electrocatalytic CO2 reduction performance. The introduction of copper tunes the d-band electron configuration and enhances the adsorption of hydrogen, which impedes the hydrogen evolution reaction. The single nickel atom electrode has been successfully synthesized at 32.87mM·cm−1 and turnover frequency of 1.962h−1 at a mild overpotential of 620mV for CO formation with 97%. Faradic efficiency.", "pub_time": "2020"}
{"sha256": "dc9221d3ae0e1a5bf07dcf64777337b6c795d5681d45101e0f5b05af41987943", "doi": "10.1080/00221546.2012.11777255", "title": "Necessary but Not Sufficient: The Impact of Grutter v. Bollinger on Student of Color Enrollment in Graduate and Professional Schools in Texas ", "author": "Liliana M. Garces", "keyword": "", "abstract": "", "pub_time": "2012"}