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"description": "Case definition for suspected polio", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T11:56:57Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Kenya", + "language": "English", + "organization": "Ministry of Health", + "authors": [ + "Division of Disease Surveillance and Response" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "name": "Weakness or floppiness of the limbs in a child 15 years old or less", + "values": [ + { + "type": "symptom", + "name": "Acute flaccid paralysis", + "description": "Weakness or floppiness of the limbs of sudden onset not due to trauma" + }, + { + "type": "demographic_criteria", + "name": "15 years old or less", + "attribute": "age", + "operator": "<=", + "value": 15, + "unit": "years" + } + ] + }, + { + "type": "professional_judgment", + "name": "Clinical suspicion of polio", + "description": "Any person of any age in whom a clinician suspects polio" + } + ] + } + ], + "references": [ + { + "url": "https://nphi.go.ke/sites/default/files/2024-02/Case%20definition%20Chart_0.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Any case with weakness or floppiness of the limbs of sudden onset not due to trauma in a c hild less than \n15 years of age, or any person of any age in whom a clinician suspects polio", + "target_public_health_threats": [ + "poliomyelitis" + ], + "keywords": [ + "polio", + "poliomyelitis", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/arbovirosis_paraguay_cd.json b/machine_readable/json/arbovirosis_paraguay_cd.json new file mode 100644 index 0000000000000000000000000000000000000000..99e520518807dde6e166fbd45a02174453b92892 --- /dev/null +++ b/machine_readable/json/arbovirosis_paraguay_cd.json @@ -0,0 +1,65 @@ +{ + "title": "Open Syndrome Arbovirosis in General", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Paraguay", + "language": "English", + "organization": "Ministry of Health and Social Welfare", + "authors": [ + "Dirección General de Vigilancia de la Salud", + "Ministerio de Salud Pública y Bienestar Social" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "professional_judgment", + "name": "History of arthropod bite", + "description": "Arthropod refers to insects or arachnids, such as mosquitoes" + }, + { + "type": "symptom", + "name": "Acute fever of unknown origin (FUO)", + "description": "Fever persisting for more than 3 days without an identified cause" + } + ], + "code": { + "system": "ICD-10", + "code": "A92.9" + } + } + ], + "references": [ + { + "title": "Guía Nacional de Vigilancia y Control de Eventos de Notificación Obligatoria. Sistema Nacional de Vigilancia Epidemiológica. Paraguay, 2022", + "url": "https://dgvs.mspbs.gov.py/files/guiaNacional/Guia_de_Vigilancia_2022_act_28_julio.pdf" + } + ], + "notes": [ + "Human-readable definition was automatically translated from Spanish to English." + ], + "status": "draft", + "human_readable_definition": "Undifferentiated fever due to mosquito bite. Acute febrile syndrome with no apparent cause", + "target_public_health_threats": [ + "arbovirosis" + ], + "keywords": [ + "arbovirosis", + "Latin America" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/arbovirosis_paraguay_sd.json b/machine_readable/json/arbovirosis_paraguay_sd.json new file mode 100644 index 0000000000000000000000000000000000000000..5e4e9899562444c4d10ca765a067bfa0134d7eb2 --- /dev/null +++ b/machine_readable/json/arbovirosis_paraguay_sd.json @@ -0,0 +1,59 @@ +{ + "title": "Open Syndrome Arbovirosis in General (Syndrome Definition)", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Paraguay", + "language": "English", + "organization": "Ministry of Health and Social Welfare", + "authors": [ + "Dirección General de Vigilancia de la Salud", + "Ministerio de Salud Pública y Bienestar Social" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "diagnosis", + "name": "Mosquito-borne viral fever, unspecified", + "code": { + "system": "ICD-10", + "code": "A92.9" + } + } + ] + } + ], + "references": [ + { + "title": "Guía Nacional de Vigilancia y Control de Eventos de Notificación Obligatoria. Sistema Nacional de Vigilancia Epidemiológica. Paraguay, 2022", + "url": "https://dgvs.mspbs.gov.py/files/guiaNacional/Guia_de_Vigilancia_2022_act_28_julio.pdf" + }, + { + "url": "https://icd.who.int/browse10/2019/en#/A92.9" + } + ], + "notes": [ + "Human-readable definition was automatically translated from Spanish to English." + ], + "status": "draft", + "human_readable_definition": "Undifferentiated fever due to mosquito bite. Acute febrile syndrome with no apparent cause", + "target_public_health_threats": [ + "arbovirosis" + ], + "keywords": [ + "arbovirosis", + "Latin America", + "syndrome definition" + ], + "definition_type": "syndrome_definition" +} diff --git a/machine_readable/json/avianinfluenzainhumans_australia.json b/machine_readable/json/avianinfluenzainhumans_australia.json new file mode 100644 index 0000000000000000000000000000000000000000..dc2e78134f8e070ee7c2740989fd2a5b8adc4e6e --- /dev/null +++ b/machine_readable/json/avianinfluenzainhumans_australia.json @@ -0,0 +1,117 @@ +{ + "title": "Open Syndrome Avian Influenza in Humans (AVIH)", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2015-07-01T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Australia", + "language": "English", + "organization": "Government of Western Australia", + "authors": [ + "Department of Health Public Health and Clinical Services Division" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "Fever", + "description": ">38°C" + }, + { + "type": "symptom", + "name": "history of fever" + } + ] + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "cough" + }, + { + "type": "symptom", + "name": "rhinorrhoea" + }, + { + "type": "symptom", + "name": "myalgia" + }, + { + "type": "symptom", + "name": "headache" + }, + { + "type": "symptom", + "name": "dyspnoea" + }, + { + "type": "symptom", + "name": "diarrhoea" + } + ] + } + ] + }, + { + "type": "symptom", + "name": "conjunctivitis" + }, + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Infiltrates or evidence of an acute pneumonia on chest radiograph" + }, + { + "type": "symptom", + "name": "acute respiratory insufficiency", + "description": "hypoxaemia, severe tachypnoea" + } + ] + } + ] + } + ], + "references": [ + { + "url": "http://www.health.gov.au/casedefinitions" + } + ], + "notes": [], + "status": "draft", + "human_readable_definition": "Clinical evidence \nAn acute illness characterised by: \n \n1. Fever (>38°C) or history of fever AND one or more of; cough OR rhinorrhoea OR \nmyalgia OR headache OR dyspnoea OR diarrhoea; \nOR \n2. Conjunctivitis \nOR \n3. Infiltrates or evidence of an acute pneumonia on a chest radiograph plus evidence \nof acute respiratory insufficiency (hypoxaemia, severe tachypnoea). \n", + "target_public_health_threats": [ + "Avian Influenza in Humans" + ], + "keywords": [ + "Avian Influenza in Humans", + "AIH", + "Oceania" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/babesiosis_canada.json b/machine_readable/json/babesiosis_canada.json new file mode 100644 index 0000000000000000000000000000000000000000..09e5aafeed7f984988c93d2a2a17f013f29b7dee --- /dev/null +++ b/machine_readable/json/babesiosis_canada.json @@ -0,0 +1,81 @@ +{ + "title": "Open Syndrome Babesiosis", + "description": "Case definition for suspected babesiosis", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Canada", + "language": "English", + "organization": "Public Health Agency of Canada", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "fever" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "fatigue" + }, + { + "type": "symptom", + "name": "chills" + }, + { + "type": "symptom", + "name": "sweats" + }, + { + "type": "symptom", + "name": "headache" + }, + { + "type": "symptom", + "name": "anorexia" + }, + { + "type": "symptom", + "name": "hemolytic anemia" + }, + { + "type": "symptom", + "name": "thrombocytopenia" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "National Case Definition for Babesiosis, Canada", + "url": "https://www.canada.ca/en/public-health/services/diseases/babesiosis/health-professionals/national-case-definition.html" + } + ], + "status": "draft", + "human_readable_definition": "Babesiosis infections range in severity from asymptomatic to severe\n(occasionally fatal) depending on host and parasite factors. Most\nsymptomatic infections caused by B. microti are mild and self-limiting,\ndeveloping 1 to 4 weeks after the tick bite and 1 to 9 weeks after\ncontamination of blood products. The salient features are fever and\nnon-specific flu-like illness (malaise, fatigue, chills, sweats, and\nheadache).\n", + "target_public_health_threats": [ + "Babesiosis" + ], + "keywords": [ + "North America", + "Babesiosis" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/cholera_colombia.json b/machine_readable/json/cholera_colombia.json new file mode 100644 index 0000000000000000000000000000000000000000..2829e95601fdd594561a9af5c018cacf450f4d68 --- /dev/null +++ b/machine_readable/json/cholera_colombia.json @@ -0,0 +1,52 @@ +{ + "title": "Open Syndrome Confirmed Case of Cholera", + "description": "Laboratory confirmation with positive fecal culture for toxigenic Vibrio cholerae O1 or O139", + "scope": "specific", + "category": "confirmed", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-27T16:16:26Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Colombia", + "language": "English", + "organization": "Instituto Nacional de Salud", + "inclusion_criteria": [ + { + "type": "criterion", + "name": "Confirmation by Laboratory with Positive Culture of Stool", + "logical_operator": "OR", + "values": [ + { + "type": "diagnostic_test", + "name": "Confirmation by Laboratory with Positive Culture of Stool for Vibrio cholerae O1" + }, + { + "type": "diagnostic_test", + "name": "Confirmation by Laboratory with Positive Culture of Stool for O139 Toxigenic" + } + ] + } + ], + "references": [ + { + "citation": "Colombia. Instituto Nacional de Salud. Protocolo de Vigilancia\nen Salud Pública de Cólera. versión 4. [Internet] 2022.\nhttps://doi.org/10.33610/infoeventos.5", + "url": "https://www.ins.gov.co/buscador-eventos/Lineamientos/Pro_C%C3%B3lera.pdf" + } + ], + "notes": [ + "Human-readable definition was automatically translated from Spanish to English." + ], + "status": "draft", + "human_readable_definition": "This is a suspect case that meets any of the following criteria.\n Confirmation by laboratory with positive stool culture for toxigenic Vibrio cholerae O1 or O139.\n Confirmation by epidemiological link:\n • Individual who fits the definition of a suspect case, and has history of contact with a confirmed cholera patient within a period of five days\n • or a history of active circulation of V. cholerae serotype O1 or O139 toxigenic in the workplace or residence of the case.\n An area of active circulation is considered one where toxigenic Vibrio cholerae O1 or O139 has been isolated from biological or environmental samples (water, food or food remains).", + "target_public_health_threats": [ + "Cholera" + ], + "keywords": [ + "Latin America", + "Cholera" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/cholera_ghana.json b/machine_readable/json/cholera_ghana.json new file mode 100644 index 0000000000000000000000000000000000000000..c88fc931641c648309f20bd2dea4ff7b7ac798ad --- /dev/null +++ b/machine_readable/json/cholera_ghana.json @@ -0,0 +1,54 @@ +{ + "title": "Open Syndrome Cholera", + "description": "Case definition for suspected case of cholera", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Ghana", + "language": "English", + "organization": "Ministry of Health", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "demographic_criteria", + "name": "5 years old or more", + "attribute": "age", + "operator": ">=", + "value": 5, + "unit": "years" + }, + { + "type": "symptom", + "name": "Acute watery diarrhea" + } + ] + } + ], + "notes": [ + "If there is a cholera epidemic, a suspected case is a person age 5 years or more with acute watery diarrhoea, with or without vomiting." + ], + "references": [ + { + "url": "https://www.moh.gov.gh/wp-content/uploads/2016/02/Integrated-Disease-Surveillance-and-Response-Ghana-Guidelines.pdf" + } + ], + "status": "draft", + "human_readable_definition": "In a patient age 5 years or more, severe dehydration or death from acute watery diarrhoea\n(rice water stool).\nIf there is a cholera epidemic, a suspected case is a person age 5 years or more with acute\nwatery diarrhoea, with or without vomiting.", + "target_public_health_threats": [ + "Cholera" + ], + "keywords": [ + "Cholera", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/covid19_egypt.json b/machine_readable/json/covid19_egypt.json new file mode 100644 index 0000000000000000000000000000000000000000..8d46c44f66c9bd9b01b322d47d5f511b91aeb45d --- /dev/null +++ b/machine_readable/json/covid19_egypt.json @@ -0,0 +1,90 @@ +{ + "title": "Open Syndrome COVID-19 (Egypt)", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2020-05-30T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Egypt", + "language": "English", + "organization": "Ministry of health and population (MOHP)", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "name": "A. Any one of the epidemiological history with any of the clinical features", + "logical_operator": "OR", + "values": [ + { + "type": "epidemiological_history", + "name": "History of travel to or residence in communities where cases reported within the last 14 days" + }, + { + "type": "epidemiological_history", + "name": "In contact with a patient who has fever or respiratory symptoms or from a community with confirmed cases reported within the last 14 days" + } + ] + }, + { + "type": "criterion", + "name": "B. Assessing the presence of at least two of the following clinical features", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "symptom", + "name": "Fever and/or respiratory symptoms" + }, + { + "type": "professional_judgment", + "name": "Imaging characteristics" + }, + { + "type": "professional_judgment", + "name": "Differential CBC findings", + "description": "White blood cells is normal or decreased, with decreased lymphocytic count." + } + ] + }, + { + "type": "criterion", + "name": "C. Severe Acute Respiratory Infection (SARI) with no other obvious cause", + "logical_operator": "OR", + "values": [ + { + "type": "professional_judgment", + "name": "Severe Acute Respiratory Infection (SARI) with other obvious cause for SARI" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Masoud, Hossam & Elassal, Gehan & Zaky, Samy & Baki, Amin & Ibrahem, Hamdy & Amin, Wagdy & Abdelbary, Akram & Abdalmohsen, Ahmad & Hassany, Mohamed & Eid, Alaa & Asem, Noha & Kamal, Ehab. (2020). Management Protocol for COVID-19 Patients Version 1.4/30th May 2020 Ministry of health and population (MOHP), Egypt.", + "url": "https://www.researchgate.net/publication/344078546_Management_Protocol_for_COVID-19_Patients_Version_1430th_May_2020_Ministry_of_health_and_population_MOHP_Egypt" + } + ], + "notes": [], + "status": "draft", + "human_readable_definition": "A\nAny one of the epidemiological \nhistory with any of the clinical \nfeatures.\nepidemiological history:\n1. History of travel to or \nresidence in communities \nwhere cases reported within \nthe last 14 days.\n2. In contact with viral RNA \npositive people\nwithin the last 14 days.\n3. In contact with a patient who \nhas fever or respiratory \nsymptoms or from a \ncommunity\nwith confirmed cases reported \nwithin the last 14 days.\nB\nAsessing the presence of at \nleast two of the following \nclinical features:\n1.Fever and/or respiratory \nsymptoms.\n2.Imaging characteristics. \nCT scan is preferred, if not \nappicable do CXR\n3.Differential CBC findings:\nwhite blood cells is normal \nor decreased, with decreased \nlymphocytic count.\nC\nSevere Acute Respiratory \nInfection\n(SARI) with no other \nobvious cause.\n", + "target_public_health_threats": [ + "COVID-19" + ], + "keywords": [ + "COVID-19", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/covid19_philippines.json b/machine_readable/json/covid19_philippines.json new file mode 100644 index 0000000000000000000000000000000000000000..7a1d4c69abfb3f81e297c06bc984dd9405518972 --- /dev/null +++ b/machine_readable/json/covid19_philippines.json @@ -0,0 +1,102 @@ +{ + "title": "Open Syndrome COVID-19 (Philippines)", + "description": "COVID-19 suspected case definition for the Philippines", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Philippines", + "language": "English", + "organization": "Department of Health", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "fever" + }, + { + "type": "symptom", + "name": "cough" + } + ] + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 3 + ], + "values": [ + { + "type": "symptom", + "name": "fever" + }, + { + "type": "symptom", + "name": "cough" + }, + { + "type": "symptom", + "name": "general weakness" + }, + { + "type": "symptom", + "name": "fatigue" + }, + { + "type": "symptom", + "name": "headache" + }, + { + "type": "symptom", + "name": "myalgia" + }, + { + "type": "symptom", + "name": "sore throat" + }, + { + "type": "symptom", + "name": "coryza" + }, + { + "type": "symptom", + "name": "dyspnea" + }, + { + "type": "symptom", + "name": "anorexia/nausea/vomiting/diarrhea" + }, + { + "type": "professional_judgment", + "name": "altered mental status" + } + ] + } + ] + } + ], + "references": [], + "status": "draft", + "human_readable_definition": "A. Suspect Case \n1. A person who meets the clinical AND epidemiologic criteria: \na. Clinical criteria \ni. Acute onset of fever AND cough OR \nii. Acute onset of any of the three or more of the following signs or symptoms: \nfever, cough, general weakness, fatigue, headache, myalgia, sor e throat, \ncoryza, dyspnea, anorexia/nausea/vomiting/diarrhea, altered men tal \nstatus \nb. Epidemiologic criteria \ni. Residing or working in an area with high risk of transmissio n of the virus: \nfor example, closed residential settings and humanitarian settings such as \ncamp and camp-like settings for displaced persons, any time within the 14 \ndays prior to symptoms onset; OR \nii. Residing in or travel to an area with community transmission anytime within \nthe 14 days prior to symptom onset OR \niii. Working in health settings including within health facilit ies and within \nhouseholds, anytime within the 14 days prior to symptoms onset \nc. Patient with severe acute respiratory illness (SARI: acute r espiratory infection \nwith history of fever or measured fever > 38 C, and cough with onset within the \nlast 10 days and who require hospitalization) \n", + "target_public_health_threats": [ + "COVID-19" + ], + "keywords": [ + "COVID-19", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/dengue_usa.json b/machine_readable/json/dengue_usa.json new file mode 100644 index 0000000000000000000000000000000000000000..b0e2305ada16c358b751b12455861713bc4efbf7 --- /dev/null +++ b/machine_readable/json/dengue_usa.json @@ -0,0 +1,124 @@ +{ + "title": "Open Syndrome Dengue", + "description": "Case definition for dengue surveillance based on chief complaints and multiple diagnostic coding systems", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "United States", + "language": "English", + "organization": "CDC", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "diagnosis", + "name": "Dengue in chief complaint", + "description": "Dengue word in chief complaint field", + "operator": "regex", + "regex_pattern": "dengue", + "regex_flags": "i" + }, + { + "type": "diagnosis", + "name": "Dengue fever", + "description": "Dengue fever (A90) or Dengue hemorrhagic fever (A91)", + "code": { + "system": "ICD-10", + "code": "A90" + } + }, + { + "type": "diagnosis", + "name": "Dengue hemorrhagic fever", + "code": { + "system": "ICD-10", + "code": "A91" + } + }, + { + "type": "diagnosis", + "name": "Dengue", + "code": { + "system": "ICD-9", + "code": "061", + "display": "Dengue" + } + }, + { + "type": "diagnosis", + "name": "Dengue", + "code": { + "system": "SNOMED-CT", + "code": "38362002", + "display": "Dengue" + } + }, + { + "type": "diagnosis", + "name": "Severe Dengue", + "code": { + "system": "SNOMED-CT", + "code": "20927009", + "display": "Severe Dengue" + } + }, + { + "type": "diagnosis", + "name": "Dengue shock syndrome", + "code": { + "system": "SNOMED-CT", + "code": "409671005", + "display": "Dengue shock syndrome" + } + }, + { + "type": "diagnosis", + "name": "Myelitis caused by Dengue virus", + "code": { + "system": "SNOMED-CT", + "code": "866057003", + "display": "Myelitis caused by Dengue virus" + } + }, + { + "type": "diagnosis", + "name": "Encephalitis caused by Dengue virus", + "code": { + "system": "SNOMED-CT", + "code": "1163101003", + "display": "Encephalitis caused by Dengue virus" + } + } + ] + } + ], + "references": [ + { + "citation": "Dengue Case Definition v1", + "url": "https://knowledgerepository.syndromicsurveillance.org/dengue-v1" + } + ], + "notes": [ + "Case definition based on Chief Complaint Discharge Diagnosis (CCDD) parsed field", + "No exclusion terms or codes are used in this query" + ], + "status": "draft", + "human_readable_definition": "", + "target_public_health_threats": [ + "Dengue" + ], + "keywords": [ + "Dengue", + "North America", + "Arbovirus" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/denguefever_malaysia.json b/machine_readable/json/denguefever_malaysia.json new file mode 100644 index 0000000000000000000000000000000000000000..1d74e0d78ea4a3afdf46b3b9bbd17eb5e3cd514a --- /dev/null +++ b/machine_readable/json/denguefever_malaysia.json @@ -0,0 +1,83 @@ +{ + "title": "Open Syndrome Dengue Fever", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Malaysia", + "language": "English", + "organization": "Ministry of Health", + "authors": [ + "Vector Borne Disease Sector - Disease Control Division" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Acute onset of high grade fever of usually 2-5 days or more" + }, + { + "type": "criterion", + "name": "Other symptoms", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "symptom", + "name": "headache" + }, + { + "type": "symptom", + "name": "retro-orbital pain" + }, + { + "type": "symptom", + "name": "myalgia" + }, + { + "type": "symptom", + "name": "arthralgia" + }, + { + "type": "symptom", + "name": "rash" + }, + { + "type": "symptom", + "name": "mild haemorrhagic manifestation", + "description": "e.g. epistaxis, gums bleeding and petechiae" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Case Definition of Infectious Disease 3rd Edition 2017", + "url": "https://www2.moh.gov.my/moh/resources/Penerbitan/Garis%20Panduan/Pengurusan%20KEsihatan%20&%20kawalan%20pykit/Case_Definition_Of_Infectious_Disease_3rd_Edition_2017.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Acute onset of high grade fever of usually 2-5 days or more associated with two or more\nof the following: headache, retro-orbital pain, myalgia, arthralgia, rash and mild\nhaemorrhagic manifestation (epistaxis, gums bleeding and petechiae).", + "target_public_health_threats": [ + "Dengue fever" + ], + "keywords": [ + "Dengue", + "Arbovirosis", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/diabetesmellitusnoinsulinodepedientetypeII_mexico.json b/machine_readable/json/diabetesmellitusnoinsulinodepedientetypeII_mexico.json new file mode 100644 index 0000000000000000000000000000000000000000..82cc4c534fa98595cdd110d70f6433f538ab4ee3 --- /dev/null +++ b/machine_readable/json/diabetesmellitusnoinsulinodepedientetypeII_mexico.json @@ -0,0 +1,61 @@ +{ + "title": "Open Syndrome Non-Insulin-Dependent Diabetes Mellitus 'Type II' (E11-E14)", + "description": "", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2021-03-01T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Mexico", + "language": "English", + "organization": "Secretaría de Salud", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "poliuria" + }, + { + "type": "symptom", + "name": "polidipsia" + }, + { + "type": "symptom", + "name": "polifagia" + }, + { + "type": "diagnostic_test", + "name": "Casual plasma glucose greater than or equal to 200 mg/dL.", + "operator": ">=", + "value": 200, + "unit": "mg/dL" + } + ] + } + ], + "references": [ + { + "url": "https://epidemiologia.salud.gob.mx/gobmx/salud/documentos/manuales/DefinicionesOperacionales_Padecimientos_Sujetos_a_VE.pdf" + } + ], + "notes": [ + "Type of diabetes in which there is insulin resistance and a concomitant deficiency in its production, which can be absolute or relative. Patients are usually over 30 years of age when the diagnosis is made, they are obese and have relatively few classic symptoms." + ], + "status": "draft", + "human_readable_definition": "Toda persona que reúna los siguientes criterios:\npoliuria, polidipsia y polifagia, más una glucemia plasmática casual mayor\no igual a 200 mg/dl", + "target_public_health_threats": [ + "Diabetes" + ], + "keywords": [ + "Diabetes", + "North America" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/diarrhea_pacificislands.json b/machine_readable/json/diarrhea_pacificislands.json new file mode 100644 index 0000000000000000000000000000000000000000..21b52ecd774f5085b8a3a8427a4e46f991043abc --- /dev/null +++ b/machine_readable/json/diarrhea_pacificislands.json @@ -0,0 +1,49 @@ +{ + "title": "Open Syndrome Diarrhea", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "location": "Pacific Islands", + "language": "English", + "organization": "Pacific Public Health Surveillance Network (PPHSN)", + "inclusion_criteria": [ + { + "type": "symptom", + "name": "Three or more loose or watery stools", + "attribute": "stools", + "operator": ">=", + "value": 3, + "unit": "occurrences" + }, + { + "type": "professional_judgment", + "name": "Less than 24 hours", + "attribute": "Time period", + "operator": "<", + "value": 24, + "unit": "hours" + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T13:59:09Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "references": [ + { + "url": "https://www.pphsn.net/wp-content/uploads/2018/06/Towards_standardised_syndromic_event-based_surv_system_Pacific.pdf" + } + ], + "status": "draft", + "human_readable_definition": "3 or more loose or\nwatery stools in 24 hrs", + "target_public_health_threats": [ + "Diarrhea" + ], + "keywords": [ + "Diarrhea", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/ebola_spain.json b/machine_readable/json/ebola_spain.json new file mode 100644 index 0000000000000000000000000000000000000000..e43ac050a974a733437d682dc187fe4468f28acb --- /dev/null +++ b/machine_readable/json/ebola_spain.json @@ -0,0 +1,89 @@ +{ + "title": "Open Syndrome Ebola", + "description": "", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "location": "Spain", + "language": "English", + "organization": "Ministerio de Sanidad, Consumo y Bienestar Social", + "authors": [ + "Ponencia de Alertas de Salud Pública y Planes de Preparación y Respuesta", + "Ponencia de Salud Laboral" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Fever", + "attribute": "body_temperature", + "operator": ">=", + "value": 37.7, + "unit": "celsius" + }, + { + "name": "At least one of the following symptoms", + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Severe headache", + "description": "intense" + }, + { + "type": "symptom", + "name": "Vomiting" + }, + { + "type": "symptom", + "name": "Diarrhea" + }, + { + "type": "symptom", + "name": "Abdominal pain" + }, + { + "type": "symptom", + "name": "Muscle pain" + }, + { + "type": "symptom", + "name": "Unexplained hemorrhagic manifestation" + } + ] + } + ] + } + ], + "notes": [ + "Para valorar la fiebre, se deberá tener en cuenta si está tomando antitérmicos, está en situación de inmunodepresión o cualquier otra situación que pueda afectar a la temperatura corporal, como son los niños, ancianos, etc. En los lactantes, especialmente en los menores de 3 meses, la fiebre puede no ser evidente y se deben valorar como criterio clínico los síntomas y signos de afectación sistémica." + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T13:41:32Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "open_syndrome_version": "1.0.0", + "references": [ + { + "url": "https://www.sanidad.gob.es/profesionales/saludPublica/ccayes/alertasActual/ebola/documentos/Protocolo_actuacion_Ebola.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Se considerará caso en investigación aquella persona que cumpla los criterios epidemiológico y clínico descritos a\ncontinuación. A la hora de considerar un caso en investigación, el criterio epidemiológico debe ser determinante.\nCriterio epidemiológico: al menos uno de los siguientes antecedentes de posibles exposiciones durante los\n21 días previos al inicio de síntomas:\n– Antecedente de estancia en un área con transmisión de EVE y haber tenido durante esa estancia\ncontacto con un caso (en investigación o confirmado)1 o con sus fluidos corporales/muestras\nbiológicas, o contacto con una persona enferma con sintomatología compatible.\n– Sin antecedente de estancia en un área donde hay transmisión de EVE: contacto con un caso (en\ninvestigación o confirmado) o con sus fluidos corporales/muestras biológicas.\nY\nCriterio clínico: Fiebre* (≥ 37,7 º C) con al menos otro síntoma compatible con la clínica de la enfermedad\n(cefalea intensa, vómitos, diarrea, dolor abdominal, dolor muscular o manifestación hemorrágica no\nexplicada)\n* Para valorar la fiebre, se deberá tener en cuenta si está tomando antitérmicos, está en situación de\ninmunodepresión o cualquier otra situación que pueda afectar a la temperatura corporal, como son\nlos niños, ancianos, etc. En los lactantes, especialmente en los menores de 3 meses, la fiebre puede no\nser evidente y se deben valorar como criterio clínico los síntomas y signos de afectación sistémica.\nEl criterio clínico en contactos en seguimiento por haber estado expuestos a un caso de EVE será fiebre o\nun cuadro clínico compatible con la enfermedad.", + "target_public_health_threats": [ + "Ebola" + ], + "keywords": [ + "Ebola", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/equineencephalitis_guatemala.json b/machine_readable/json/equineencephalitis_guatemala.json new file mode 100644 index 0000000000000000000000000000000000000000..a53d80232c59b2c3be870b6d8700e57f3f0f660f --- /dev/null +++ b/machine_readable/json/equineencephalitis_guatemala.json @@ -0,0 +1,108 @@ +{ + "title": "Open Syndrome Suspected Case of Equine Encephalitis", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-27T17:02:03Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "status": "draft", + "open_syndrome_version": "1.0.0", + "scope": "broad", + "version": "1.0.0", + "language": "English", + "organization": "Ministerio de Salud Pública y Asistencia Social", + "location": "Guatemala", + "category": "suspected", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Sudden onset fever" + }, + { + "type": "criterion", + "name": "One or more of the following neurological signs", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Headache" + }, + { + "type": "symptom", + "name": "Disorientation" + }, + { + "type": "symptom", + "name": "Tremors" + }, + { + "type": "symptom", + "name": "Convulsions" + }, + { + "type": "symptom", + "name": "Paresthesias" + }, + { + "type": "symptom", + "name": "Paralysis" + }, + { + "type": "symptom", + "name": "Somnolence" + }, + { + "type": "symptom", + "name": "Alteration of consciousness" + }, + { + "type": "symptom", + "name": "Stupor" + }, + { + "type": "symptom", + "name": "Rigidity of neck" + } + ] + }, + { + "type": "criterion", + "name": "Travel history", + "logical_operator": "OR", + "values": [ + { + "type": "epidemiological_history", + "name": "Visited regions with presence of equids (horses, donkeys and mules)" + }, + { + "type": "epidemiological_history", + "name": "Suffered mosquito bites in areas with suspected equine encephalitis deaths" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Protocolos de Vigilancia Epidemiológica Enfermedades Zoonóticas. Ministerio de Salud Pública y Asistencia Social. Guatemala. 2018.", + "url": "http://bvs.gt/eblueinfo/VS/VS_008.pdf" + } + ], + "human_readable_definition": "Toda persona que presente fiebre de inicio\nrepentino, asociada a uno o más de los siguientes signos neurológicos: cefalea,\ndesorientación, temblores, convulsiones, parestesias, o algún tipo de parálisis,\nsomnolencia, alteración del estado de conciencia, estupor, rigidez de nuca y que hayan\nvisitado regiones con presencia de équidos (caballos, asnos y mulas) o bien, haber sufrido\npicaduras de mosquitos en áreas con muerte de estos équidos sospechosos de padecer\nencefalitis equina.", + "target_public_health_threats": [ + "Equine encephalitis" + ], + "keywords": [ + "Equine encephalitis", + "North America" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/extremetemperaturescold_argentina.json b/machine_readable/json/extremetemperaturescold_argentina.json new file mode 100644 index 0000000000000000000000000000000000000000..7326f17ccaa0add75e6b3cd8bfbf04c79ddd85a3 --- /dev/null +++ b/machine_readable/json/extremetemperaturescold_argentina.json @@ -0,0 +1,84 @@ +{ + "title": "Open Syndrome Cold Exposure", + "description": "Case definition for suspected cold exposure in individuals with history of extreme cold exposure during Early Temperature Extreme Alert by National Meteorological Service, and clinical symptoms attributable to low body temperature (36°C or lower) and 2 or more of the following: shivering, altered consciousness, weak pulse, slow breathing, local tissue damage due to freezing.", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "location": "Argentina", + "language": "English", + "organization": "Ministerio de Salud", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Low body temperature", + "attribute": "body_temperature", + "operator": "<=", + "value": 36, + "unit": "celsius" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "symptom", + "name": "Shivering" + }, + { + "type": "symptom", + "name": "Altered consciousness" + }, + { + "type": "symptom", + "name": "Weak pulse" + }, + { + "type": "symptom", + "name": "Slow breathing" + }, + { + "type": "symptom", + "name": "Local tissue damage due to freezing" + }, + { + "type": "symptom", + "name": "Cold, red skin in babies" + } + ] + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T12:20:55Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "notes": [ + "ICD-10 code COLD: X31 (Exposure to excessive natural cold)" + ], + "references": [ + { + "url": "https://www.argentina.gob.ar/sites/default/files/2019/10/msal-manual_de_normas_y_procedimientos_de_vigilancia_y_control_de_eno_2022.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Toda persona con antecedentes de\nexposición a frío extremo en circunstancia de Alerta Temprana por Temperatura\nExtrema (frío) del Servicio Meteorológico Nacional, y sintomatología clínica\natribuible. Temperatura corporal igual o menor a 36 ºC y 2 o más de los siguientes\nsíntomas, a saber:\nSignos y síntomas atribuibles: escalofríos, alteración del estado de conciencia, pulso\ndébil, bradipnea, daño tisular local causado por el enfriamiento. Piel fría y roja en\nbebés.", + "target_public_health_threats": [ + "Cold" + ], + "keywords": [ + "Cold", + "South America", + "Climate-related" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/extremetemperaturesheat_argentina.json b/machine_readable/json/extremetemperaturesheat_argentina.json new file mode 100644 index 0000000000000000000000000000000000000000..be0073b56ea63c037821725bc47ef7cc3ca8503a --- /dev/null +++ b/machine_readable/json/extremetemperaturesheat_argentina.json @@ -0,0 +1,101 @@ +{ + "title": "Open Syndrome Heat Exposure", + "description": "Case definition for suspected heat exposure in individuals with history of extreme heat exposure during Early Temperature Extreme Alert by National Meteorological Service, and clinical symptoms attributable to high body temperature (39°C or higher) and 2 or more of the following: sweating, nausea/vomiting, hypotension, tachycardia, tachypnea, altered consciousness, seizures, fainting. In infants: excessive sweating, irritated skin due to sweating.", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "location": "Argentina", + "language": "English", + "organization": "Ministerio de Salud", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "High body temperature", + "attribute": "body_temperature", + "operator": ">=", + "value": 39, + "unit": "celsius" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "symptom", + "name": "Warm skin" + }, + { + "type": "symptom", + "name": "Sweating" + }, + { + "type": "symptom", + "name": "Nausea/vomiting" + }, + { + "type": "symptom", + "name": "Hypotension" + }, + { + "type": "symptom", + "name": "Tachycardia" + }, + { + "type": "symptom", + "name": "Tachypnea" + }, + { + "type": "symptom", + "name": "Altered consciousness" + }, + { + "type": "symptom", + "name": "Seizures" + }, + { + "type": "symptom", + "name": "Fainting" + }, + { + "type": "symptom", + "name": "Excessive sweating (infants)", + "description": "Irritated skin due to sweating (infants)" + } + ] + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T12:20:55Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "notes": [ + "ICD-10 code HEAT: X30 (Exposure to excessive natural heat), T67 (Effects of heat and light)" + ], + "references": [ + { + "url": "https://www.argentina.gob.ar/sites/default/files/2019/10/msal-manual_de_normas_y_procedimientos_de_vigilancia_y_control_de_eno_2022.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Toda persona con antecedentes de\nexposición a calor extremo en circunstancia de Alerta Temprana por Temperatura\nExtrema (calor) del Servicio Meteorológico Nacional, y sintomatología clínica\natribuible - Temperatura corporal mayor o igual a 39 ºC y 2 o más de los siguientes\nsíntomas, a saber:\nSignos y síntomas atribuibles: piel caliente, sudoración abundante en un primer\nmomento o escasa, náuseas y/o vómitos, hipotensión, taquicardia y taquipnea,\nalteración del estado de conciencia, convulsiones, desmayo. En bebés: sudoración\nabundante, piel irritada por sudor.", + "target_public_health_threats": [ + "Heat" + ], + "keywords": [ + "Heat", + "South America", + "Climate-related" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/humannipahvirus_bangladesh.json b/machine_readable/json/humannipahvirus_bangladesh.json new file mode 100644 index 0000000000000000000000000000000000000000..cbe3ac375e987e34b975501f7944cde5e94e0cfb --- /dev/null +++ b/machine_readable/json/humannipahvirus_bangladesh.json @@ -0,0 +1,68 @@ +{ + "title": "Open Syndrome Nipah Like Illness", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Bangladesh", + "language": "English", + "organization": "", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "Fever (axillary temperature >38.5°C)" + }, + { + "type": "professional_judgment", + "name": "history of raised temperature prior to hospitalization" + } + ] + }, + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "any sign/symptom of lung pathology" + }, + { + "type": "symptom", + "name": "any sign/symptom of brain pathology" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Satter SM, Aquib WR, Sultana S, Sharif AR, Nazneen A, et al. (2023) Tackling a global epidemic threat: Nipah surveillance in Bangladesh, 2006–2021. PLOS Neglected Tropical Diseases 17(9): e0011617.", + "url": "https://doi.org/10.1371/journal.pntd.0011617" + } + ], + "status": "draft", + "human_readable_definition": "Fever (axillary temperature > 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of brain pathology\nOR\nFever (axillary temperature > 38.5 °C) or history of raised temperature prior to hospitalization AND any sign/symptom of lung pathology", + "target_public_health_threats": [ + "Nipah virus" + ], + "keywords": [ + "Nipah virus", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/influenzalikeillness_africa_africacdc.json b/machine_readable/json/influenzalikeillness_africa_africacdc.json new file mode 100644 index 0000000000000000000000000000000000000000..474c654482921d10a7c1dbb3fe9d3110fc5ae8fe --- /dev/null +++ b/machine_readable/json/influenzalikeillness_africa_africacdc.json @@ -0,0 +1,55 @@ +{ + "title": "Open Syndrome Influenza-Like Illness (ILI) Africa CDC", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "language": "English", + "organization": "Africa CDC", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Measured fever", + "attribute": "body_temperature", + "operator": ">=", + "value": 38, + "unit": "degrees Celsius" + }, + { + "type": "symptom", + "name": "Cough" + }, + { + "type": "symptom", + "name": "Onset within the last 10 days" + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T19:20:46Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "open_syndrome_version": "1.0.0", + "references": [ + { + "url": "https://au.int/sites/default/files/documents/38350-doc-protocol_for_enhanced_sari_and_ili_surveillance_for_covid-19_in_africa_eng.pdf" + } + ], + "location": "Africa", + "status": "draft", + "human_readable_definition": "An acute respiratory infection with:\n•\nmeasured fever of ≥ 38 °C\n•\nand cough\n•\nwith onset within the last 10 days", + "target_public_health_threats": [ + "Influenza-like illness" + ], + "keywords": [ + "Influenza-like illness", + "Africa" + ], + "definition_type": "case_definition" +} \ No newline at end of file diff --git a/machine_readable/json/influenzalikeillness_brazil.json b/machine_readable/json/influenzalikeillness_brazil.json new file mode 100644 index 0000000000000000000000000000000000000000..90f39ce70c7c4e7ed66737fd7ee232469c3e3d42 --- /dev/null +++ b/machine_readable/json/influenzalikeillness_brazil.json @@ -0,0 +1,86 @@ +{ + "title": "Open Syndrome Influenza-like Illness (ILI)", + "description": "Standardized case definition of suspected influenza-like illness for adults", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org/case-definitions", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Brazil", + "language": "English", + "organization": "Ministry of Health", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Fever", + "description": "Sudden onset fever, even if self-reported" + }, + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "Cough" + }, + { + "type": "symptom", + "name": "Sore throat" + } + ] + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Headache" + }, + { + "type": "symptom", + "name": "Myalgia" + }, + { + "type": "symptom", + "name": "Arthralgia" + } + ] + } + ] + } + ], + "exclusion_criteria": [ + { + "type": "diagnosis", + "name": "Other specific diagnosis", + "description": "Presence of any other specific diagnosis that explains the symptoms" + } + ], + "references": [ + { + "url": "https://www.gov.br/ebserh/pt-br/hospitais-universitarios/regiao-sudeste/hc-ufu/saude/epidemiologia/protocolos/protocolo/protocolo-de-sindrome-gripal-e-sindrome-respiratoria-aguda-grave-com-enfase-em-influenza" + } + ], + "status": "draft", + "human_readable_definition": "Indivíduo que apresente febre de início súbito, mesmo que referida,\nacompanhada de tosse ou dor de garganta e pelo menos um dos seguin-\ntes sintomas: cefaleia, mialgia ou artralgia, na ausência de outro diagnós-\ntico específico.", + "target_public_health_threats": [ + "Influenza-like Illness (ILI)" + ], + "keywords": [ + "Influenza-like Illness (ILI)", + "South America" + ], + "definition_type": "case_definition" +} \ No newline at end of file diff --git a/machine_readable/json/intussusception_vietnam.json b/machine_readable/json/intussusception_vietnam.json new file mode 100644 index 0000000000000000000000000000000000000000..4bccc56e397f719b0ade33b018fa7b48d5e4837e --- /dev/null +++ b/machine_readable/json/intussusception_vietnam.json @@ -0,0 +1,277 @@ +{ + "title": "Open Syndrome Acute Intussusception in infants", + "description": "Case definition for acute intussusception in infants", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Vietnam", + "language": "English", + "organization": "Vietnam Ministry of Health", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "criterion", + "name": "Evidence of intestinal obstruction", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "bile-stained vomiting" + }, + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "examination findings of acute abdominal distension and abnormal or absent bowel sounds" + }, + { + "type": "symptom", + "name": "fluid levels and dilated bowel loops on plain abdominal radiograph" + } + ] + } + ] + }, + { + "type": "criterion", + "name": "Features of intestinal invagination", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "abdominal mass" + }, + { + "type": "symptom", + "name": "rectal mass" + }, + { + "type": "symptom", + "name": "intestinal prolapse" + }, + { + "type": "diagnostic_test", + "name": "plain abdominal radiograph showing a visible intussusceptum or soft tissue mass" + }, + { + "type": "diagnostic_test", + "name": "abdominal ultrasound showing a visible intussusceptum or soft tissue mass" + }, + { + "type": "diagnostic_test", + "name": "abdominal CT scan showing a visible intussusceptum or soft tissue mass" + } + ] + }, + { + "type": "criterion", + "name": "Evidence of intestinal vascular compromise", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "blood per rectum" + }, + { + "type": "symptom", + "name": "stool containing red currant jelly material" + }, + { + "type": "symptom", + "name": "blood on rectal examination" + } + ] + } + ] + }, + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "criterion", + "name": "Evidence of intestinal obstruction", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "bile-stained vomiting" + }, + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "examination findings of acute abdominal distension and abnormal or absent bowel sounds" + }, + { + "type": "symptom", + "name": "fluid levels and dilated bowel loops on plain abdominal radiograph" + } + ] + } + ] + }, + { + "type": "criterion", + "name": "Features of intestinal invagination", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "abdominal mass" + }, + { + "type": "symptom", + "name": "rectal mass" + }, + { + "type": "symptom", + "name": "intestinal prolapse" + }, + { + "type": "diagnostic_test", + "name": "plain abdominal radiograph showing a visible intussusceptum or soft tissue mass" + }, + { + "type": "diagnostic_test", + "name": "abdominal ultrasound showing a visible intussusceptum or soft tissue mass" + }, + { + "type": "diagnostic_test", + "name": "abdominal CT scan showing a visible intussusceptum or soft tissue mass" + } + ] + }, + { + "type": "criterion", + "name": "Evidence of intestinal vascular compromise", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "blood per rectum" + }, + { + "type": "symptom", + "name": "stool containing red currant jelly material" + }, + { + "type": "symptom", + "name": "blood on rectal examination" + } + ] + } + ] + }, + { + "type": "criterion", + "name": "Evidence of intestinal vascular compromise", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 3 + ], + "values": [ + { + "type": "criterion", + "name": "Predisposing factors: age <1 year and male sex", + "logical_operator": "AND", + "values": [ + { + "type": "demographic_criteria", + "name": "Less than one year old", + "attribute": "age", + "operator": "<=", + "value": 1, + "unit": "years" + }, + { + "type": "demographic_criteria", + "name": "Male gender", + "attribute": "gender", + "operator": "==", + "value": "male" + } + ] + }, + { + "type": "symptom", + "name": "abdominal pain" + }, + { + "type": "symptom", + "name": "vomiting" + }, + { + "type": "symptom", + "name": "lethargy" + }, + { + "type": "symptom", + "name": "pallor" + }, + { + "type": "symptom", + "name": "hypovolemic shock" + }, + { + "type": "diagnostic_test", + "name": "Plain abdominal radiograph showing an abnormal but non-specific bowel gas pattern", + "value": "abnormal but non-specific bowel gas pattern" + } + ] + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Validation of clinical case definition of acute intussusception in infants in Viet Nam and Australia", + "url": "https://iris.who.int/handle/10665/269695" + } + ], + "status": "draft", + "human_readable_definition": "Level 1 of diagnostic certainty\nSurgical criteria:\nThe demonstration of invagination of the intestine at surgery;\nand/or\nRadiological criteria:\nThe demonstration of invagination of the intestine by either air or liquid contrast enema;\nor\nThe demonstration of an intra-abdominal mass by abdominal ultrasound with specific characteristic featuresb that is proven to be reduced by\nhydrostatic enema on post-reduction ultrasound;\nand/or\nAutopsy criteria:\nThe demonstration of invagination of the intestine.\nLevel 2 of diagnostic certainty\nClinical criteria:\nTwo major criteria (see table for major and minor criteria for diagnosis below);\nor\nOne major criterionc and three minor criteria (see table for major and minor criteria for diagnosis below).\nLevel 3 of diagnostic certainty\nClinical criteria:\nFour or more minor criteria (see minor criteria for diagnosis below).\nAny level of diagnostic certainty\nIn the absence of surgical criteria with the definitive demonstration of an alternative cause of bowel obstruction or intestinal infarction at surgery\n(e.g., volvulus or congenital pyloric stenosis).\nMajor and minor criteria used in the case definition for the diagnosis of intussusception\nMajor criteria\n1. Evidence of intestinal obstruction: 2. Features of intestinal invagination 3. Evidence of intestinal vascular\ni. History of bile-stained vomiting; One or more of the following: compromise or venous congestion:\nand either i. abdominal mass; i. Passage of blood per rectum;\nii. Examination findings of acute ii. rectal mass; or\nabdominal distension and abnormal iii. intestinal prolapse; or absent bowel sounds; iv. plain abdominal radiograph showing a ii. Passage of a stool containing\n“red currant jelly” material;\nor visible intussusceptum or soft tissue mass; or\niii. Plain abdominal radiograph showing v. abdominal ultrasound showing a visible iii. Blood detected on rectal\nfluid levels and dilated bowel loops.\nintussusceptum or soft tissue mass; examination.\nvi. abdominal CT scan showing a visible\nintussusceptum or soft tissue mass.\nMinor criteria\ni. Predisposing factors: age <1 year and male sex; ii. Abdominal pain; iii. Vomiting;d v. Pallor;e\nvi. Hypovolemic shock;\nvii. Plain abdominal radiograph showing an abnormal but non-specific\niv. Lethargy;e bowel gas pattern.", + "target_public_health_threats": [ + "Intussusception" + ], + "keywords": [ + "Intussusception", + "Asia" + ], + "definition_type": "case_definition" +} \ No newline at end of file diff --git a/machine_readable/json/legionnairesdisease_uk.json b/machine_readable/json/legionnairesdisease_uk.json new file mode 100644 index 0000000000000000000000000000000000000000..9c42695eb4f6d19d4181cbd9141fb3d96bae6c29 --- /dev/null +++ b/machine_readable/json/legionnairesdisease_uk.json @@ -0,0 +1,49 @@ +{ + "title": "Open Syndrome Probable Legionnaires' Disease", + "description": "Case definition for a probable case of Legionnaires' disease in the context of an outbreak", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "location": "England", + "language": "English", + "organization": "Public Health England", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "name": "Suspected case of pneumonia and exposure to an outbreak", + "values": [ + { + "type": "diagnosis", + "name": "Pneumonia", + "description": "Clinical or radiological diagnosis of pneumonia" + }, + { + "type": "epidemiological_history", + "name": "Outbreak exposure", + "description": "Location and onset date(s) meet the outbreak-specific case definition for the exposure category: community-acquired, healthcare-associated and travel-associated." + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T13:23:40Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "references": [ + { + "url": "https://www.gov.uk/government/publications/legionnaires-disease-clinical-case-definitions/legionnaires-disease-case-definitions" + } + ], + "status": "draft", + "human_readable_definition": "A case with clinical or radiological diagnosis of pneumonia but no\nmicrobiological evidence for confirmation of Legionella infection (above) is\nconsidered a probable case where the location and onset date(s) meet the\noutbreak-specific case definition for the exposure category", + "target_public_health_threats": [ + "Legionnaires' disease" + ], + "keywords": [ + "Legionnaires' disease" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/leptospirosis_germany.json b/machine_readable/json/leptospirosis_germany.json new file mode 100644 index 0000000000000000000000000000000000000000..bea2e82f4cdb15c2ebfeaf2a575a64599dd8c545 --- /dev/null +++ b/machine_readable/json/leptospirosis_germany.json @@ -0,0 +1,80 @@ +{ + "title": "Open Syndrome Leptospirosis", + "description": "Case definition for suspected leptospirosis in Germany", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T09:13:10Z", + "language": "English", + "location": "Germany", + "organization": "Robert Koch Institute", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "General symptoms" + }, + { + "type": "symptom", + "name": "Dyspnea (respiratory distress)" + }, + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "symptom", + "name": "Hemorrhagia (e.g., pulmonary hemorrhage, subconjunctival hemorrhage)" + }, + { + "type": "symptom", + "name": "Cough" + }, + { + "type": "symptom", + "name": "Icterus (jaundice)" + }, + { + "type": "professional_judgment", + "name": "Meningitis or meningoencephalitis" + }, + { + "type": "symptom", + "name": "Myocarditis (myocardial inflammation)" + }, + { + "type": "symptom", + "name": "Renal function disorder" + }, + { + "type": "professional_judgment", + "name": "Death due to disease" + } + ] + } + ], + "published_by": [ + "Open Syndrome Initiative" + ], + "references": [ + { + "citation": "", + "url": "https://www.rki.de/DE/Content/Infekt/IfSG/Falldefinition/Downloads/Falldefinitionen_des_RKI_2023.pdf?__blob=publicationFile" + } + ], + "status": "draft", + "human_readable_definition": "Klinisches Bild einer akuten Leptospirose, definiert als mindestens eines der neun folgenden Kriterien:\n- ►allgemeine Krankheitszeichen,\n- Dyspnoe (Atemstörung),\n- ►Fieber,\n- Hämorrhagien (z.B. Lungenblutungen, subkonjunktivale Blutungen),\n- Husten,\n- Ikterus (Gelbsucht),\n- Meningitis oder Meningoenzephalitis,\n- Myokarditis (Herzmuskelentzündung),\n- ►Nierenfunktionsstörung\nODER ►krankheitsbedingter Tod.", + "target_public_health_threats": [ + "Leptospirosis" + ], + "keywords": [ + "Leptospirosis", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/malaria_nigeria.json b/machine_readable/json/malaria_nigeria.json new file mode 100644 index 0000000000000000000000000000000000000000..5424ce4b7b2b9d20c2d49d42799bbe3ee52ab77f --- /dev/null +++ b/machine_readable/json/malaria_nigeria.json @@ -0,0 +1,48 @@ +{ + "title": "Open Syndrome Unconfirmed Severe Malaria", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "status": "draft", + "location": "Nigeria", + "language": "English", + "organization": "Nigeria Centre for Disease Control and Prevention", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "description": "Any patient hospitalized with severe febrile disease with accompanying vital organ dysfunction diagnosed clinically.", + "values": [ + { + "type": "symptom", + "name": "severe febrile illness" + }, + { + "type": "professional_judgment", + "name": "vital organ dysfunction" + } + ] + } + ], + "references": [ + { + "url": "https://ncdc.gov.ng/themes/common/docs/protocols/31_1503912332.pdf" + } + ], + "human_readable_definition": "Any patient hospitalized with severe febrile disease with accompanying vital organ\ndysfunction diagnosed clinically.", + "target_public_health_threats": [ + "Malaria" + ], + "keywords": [ + "Malaria", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/measles_ethiopia.json b/machine_readable/json/measles_ethiopia.json new file mode 100644 index 0000000000000000000000000000000000000000..6a47ce5a5ecfd9d91d1a32b6aa4f4d7372436d4f --- /dev/null +++ b/machine_readable/json/measles_ethiopia.json @@ -0,0 +1,93 @@ +{ + "title": "Open Syndrome Measles", + "description": "Case definition for measles", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-26T18:17:45Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Ethiopia", + "language": "English", + "organization": "WHO Africa", + "authors": [ + "Mekonen Getahun", + "Berhane Beyene", + "Ayesheshem Ademe", + "Birke Teshome", + "Mesfin Tefera", + "Anjelo Asha", + "Aklog Afework", + "Yoseph HaileMariyam", + "Esete Assefa", + "Kathleen Gallagher" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "name": "Symptoms or professional judgement", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "name": "Measles symptoms", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Generalized maculopapular rash" + }, + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "cough" + }, + { + "type": "symptom", + "name": "coryza" + }, + { + "type": "symptom", + "name": "conjunctivitis" + } + ] + } + ] + }, + { + "type": "professional_judgment", + "name": "any person in whom a clinician suspects measles" + } + ] + } + ], + "references": [ + { + "citation": "Getahun, M., Beyene, B., Ademe, A. et al. Epidemiology of laboratory confirmed measles virus cases in Amhara Regional State of Ethiopia, 2004–2014. BMC Infect Dis 16, 133 (2016).", + "url": "https://doi.org/10.1186/s12879-016-1457-7" + } + ], + "status": "draft", + "human_readable_definition": "National guidelines for measles surveillance are based on\nthe WHO/-AFRO Measles and Rubella Surveillance guide-\nline, and define a suspected measles case as any person\nwith a generalized maculopapular rash and fever plus one or\nmore of the following: 1) cough, 2) coryza), or 3) conjunc-\ntivitis OR any person in whom a clinician suspects measles.", + "target_public_health_threats": [ + "Measles" + ], + "keywords": [ + "Measles", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/measles_india.json b/machine_readable/json/measles_india.json new file mode 100644 index 0000000000000000000000000000000000000000..72b3865929727a018fe73c2ecd0a7db5be9cfe9e --- /dev/null +++ b/machine_readable/json/measles_india.json @@ -0,0 +1,61 @@ +{ + "title": "Open Syndrome Measles", + "description": "Case definition for suspected measles in India", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "India", + "language": "English", + "organization": "Ministry of Health and Family Welfare", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "name": "Fever with rash", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "symptom", + "name": "Maculopapular rash", + "description": "non-vesicular" + } + ] + }, + { + "type": "professional_judgment", + "name": "Clinical suspicion of measles", + "description": "Any person in whom a health worker or clinician suspects measles infection" + } + ] + } + ], + "references": [ + { + "citation": "Guidelines for Measles Surveillance - India", + "url": "https://drive.google.com/file/d/1qX0lxKjFe_qlSSnqP5pvW2gOrTNPvdrS/view" + } + ], + "status": "draft", + "human_readable_definition": "National guidelines for measles surveillance are based on\nthe WHO/-AFRO Measles and Rubella Surveillance guide-\nline, and define a suspected measles case as any person\nwith a generalized maculopapular rash and fever plus one or\nmore of the following: 1) cough, 2) coryza), or 3) conjunctivitis OR any person in whom a clinician suspects measles.", + "target_public_health_threats": [ + "Measles" + ], + "keywords": [ + "Measles", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/meningococcalmeningitis_mozambique.json b/machine_readable/json/meningococcalmeningitis_mozambique.json new file mode 100644 index 0000000000000000000000000000000000000000..ce259297a124a4666a7ba6a9da6480768ca9e107 --- /dev/null +++ b/machine_readable/json/meningococcalmeningitis_mozambique.json @@ -0,0 +1,79 @@ +{ + "title": "Open Syndrome Meningococcal Meningitis", + "description": "Suspected case definition of meningococcal meningitis in Mozambique", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Mozambique", + "language": "English", + "organization": "Ministry of Health of Mozambique", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Sudden fever", + "logical_operator": "OR", + "values": [ + { + "type": "criterion", + "name": "Rectal fever", + "description": "Temperature > 38.5°C in rectum" + }, + { + "type": "criterion", + "name": "Axillary fever", + "description": "Temperature ≥ 38.0°C in armpits" + } + ] + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Stiff neck" + }, + { + "type": "symptom", + "name": "Altered consciousness" + }, + { + "type": "symptom", + "name": "Meningeal signs", + "description": "Any other meningeal signs" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Integrated Disease Surveillance and Response in Mozambique", + "url": "https://docs.bvsalud.org/biblioref/2021/11/1344189/vigilancia-integrada-de-doencas-e-resposta-em-mocambique.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Uma pessoa com\nmanifestação súbita de febre\n(>38,5º C no recto ou 38,0º C nas\naxilas), e pescoço rígido, con-\nsciência alterada ou quaisquer\noutros sinais meníngeos.\nCaso confirmado: caso suspeito\nconfirmado através do isolamen-\nto de N. meningitidis do LCR ou\ndo sangue", + "target_public_health_threats": [ + "Meningococcal meningitis" + ], + "keywords": [ + "Meningococcal meningitis", + "Africa" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/middleeastrespiratorysyndrome_saudiarabia.json b/machine_readable/json/middleeastrespiratorysyndrome_saudiarabia.json new file mode 100644 index 0000000000000000000000000000000000000000..6d5bc59981dcde8855e3bb954aa2371fe3cdb11a --- /dev/null +++ b/machine_readable/json/middleeastrespiratorysyndrome_saudiarabia.json @@ -0,0 +1,93 @@ +{ + "title": "Open Syndrome Middle East Respiratory Syndrome (MERS)", + "description": "MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T01:18:47Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Saudi Arabia", + "language": "English", + "organization": "Ministry of Health", + "authors": [ + "Ministry of Health Command and Control Center" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "syndrome", + "name": "fever with/without respiratory symptoms" + }, + { + "type": "criterion", + "logical_operator": "AND", + "name": "Gastrointestinal symptoms with blood count abnormalities", + "values": [ + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "name": "gastrointestinal symptoms", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "diarrhea" + }, + { + "type": "symptom", + "name": "vomiting" + } + ] + }, + { + "type": "criterion", + "name": "Blood count abnormalities", + "logical_operator": "OR", + "values": [ + { + "type": "diagnostic_test", + "name": "Leukopenia", + "description": "WBC ≤ 3.5x10⁹/L" + }, + { + "type": "diagnostic_test", + "name": "Thrombocytopenia", + "description": "Platelets < 150x10⁹/L" + } + ] + } + ] + } + ] + } + ], + "exclusion_criteria": [], + "notes": [ + "Usage of Suspected case definition (section 4.1 - children and adults)." + ], + "references": [ + { + "citation": "Saudi Ministry of Health. (2018). Middle East respiratory syndrome coronavirus: Guidelines for healthcare professionals (Version 5.1)", + "url": "https://www.moh.gov.sa/ccc/healthp/regulations/documents/mers-cov%20guidelines%20for%20healthcare%20professionals%20-%20may%202018%20-%20v5.1%20%281%29.pdf#page4" + } + ], + "status": "draft", + "human_readable_definition": "Acute febrile illness (T ≥380 C)\nwith/without respiratory symptoms\nOR\nIV. Gastrointestinal symptoms\n(diarrhea or vomiting), AND\nleukopenia (WBC≤3.5x109 /L) or\nthrombocytopenia (platelets <\n150x109/L)", + "target_public_health_threats": [ + "MERS" + ], + "keywords": [ + "MERS", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/mpox_france.json b/machine_readable/json/mpox_france.json new file mode 100644 index 0000000000000000000000000000000000000000..d22a15a9f0554e04131850febed5735f5eb22009 --- /dev/null +++ b/machine_readable/json/mpox_france.json @@ -0,0 +1,64 @@ +{ + "title": "Open Syndrome Monkeypox", + "description": "", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T07:38:03Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "France", + "language": "English", + "organization": "Ministère de la Santé et de la Prévention", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Cutaneous eruption or genital, anal, or buccal mucosal ulceration", + "description": "evocative of mpox" + }, + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "description": "Greater than 38 degrees Celsius", + "name": "Fever" + }, + { + "type": "symptom", + "name": "Lymphadenopathy" + }, + { + "type": "symptom", + "name": "Odynophagia" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Cas de Mpox en Europe, définitions et conduite à tenir", + "url": "https://www.santepubliquefrance.fr/content/download/437302/file/def_cas_CAT_mpox_20042023.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Un patient suspect d'infection par le virus Monkeypox est une personne présentant\n- Une éruption cutanée ou une ou des ulcérations de la muqueuse génitale, anale ou buccale,\névocatrice de mpox\n- Isolée, ou précédée ou accompagnée d'une fièvre ressentie ou mesurée (>38°C),\nd'adénopathies ou d'une odynophagie.", + "target_public_health_threats": [ + "Monkeypox" + ], + "keywords": [ + "Monkeypox", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/mumps_ireland.json b/machine_readable/json/mumps_ireland.json new file mode 100644 index 0000000000000000000000000000000000000000..7d35d1a71c56aafea5e3c7656de576c46e45da37 --- /dev/null +++ b/machine_readable/json/mumps_ireland.json @@ -0,0 +1,50 @@ +{ + "title": "Open Syndrome Mumps", + "description": "Mumps (Mumps virus)", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2019-01-24T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Ireland", + "language": "English", + "organization": "Health Protection Surveillance Centre", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "symptom", + "name": "Sudden onset of unilateral or bilateral tender swelling of the parotid or other salivary glands" + } + ] + } + ], + "references": [ + { + "url": "https://www.hpsc.ie/a-z/vaccinepreventable/mumps/casedefinition/" + } + ], + "notes": [ + "Mumps may also present as aseptic meningitis, encephalitis, hearing loss, orchitis, oophoritis, parotitis or other salivary gland swelling, mastitis or pancreatitis." + ], + "status": "draft", + "human_readable_definition": "Any person with fever AND sudden onset of unilateral or bilateral tender swelling of the parotid or other salivary glands without other apparent cause. Mumps may also present as aseptic meningitis, encephalitis, hearing loss, orchitis, oophoritis, parotitis or other salivary gland swelling, mastitis or pancreatitis.\n\n", + "target_public_health_threats": [ + "Mumps" + ], + "keywords": [ + "Mumps", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/plague_peru.json b/machine_readable/json/plague_peru.json new file mode 100644 index 0000000000000000000000000000000000000000..1b4c0472f39e7792e2429ac0671f919cc783e345 --- /dev/null +++ b/machine_readable/json/plague_peru.json @@ -0,0 +1,69 @@ +{ + "title": "Open Syndrome Suspected Plague", + "description": "Case definition for suspected plague", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2011-01-01T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Peru", + "language": "English", + "organization": "Peru Ministry of Health", + "authors": [ + "Dirección General de Epidemiología" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Clinical presentation compatible with plague" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "name": "History of exposure to infected humans or animals", + "values": [ + { + "type": "epidemiological_history", + "name": "Exposure to infected humans or animals" + }, + { + "type": "professional_judgment", + "name": "Evidence of flea bites", + "description": "Indicates presence of fleas on the patient" + }, + { + "type": "epidemiological_history", + "name": "Residence or travel to an endemic area, within the 10 days prior" + } + ] + } + ] + } + ], + "references": [ + { + "url": "http://bvs.minsa.gob.pe/local/MINSA/3255.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Paciente con presentación clínica compatible, y con antecedentes\nepidemiológicos consistentes de:\n• Exposición a humanos o animales infectados, y/o\n• Evidencia de picaduras de pulgas, y/o\n• Residencia o viaje a un área endémica conocida, dentro de los 10 días\nprevios.", + "target_public_health_threats": [ + "Plague" + ], + "keywords": [ + "Plague", + "South America" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/smallpox_costarica.json b/machine_readable/json/smallpox_costarica.json new file mode 100644 index 0000000000000000000000000000000000000000..053589a34217df706ef3278a5bc0db8c08a8d1c6 --- /dev/null +++ b/machine_readable/json/smallpox_costarica.json @@ -0,0 +1,161 @@ +{ + "title": "Open Syndrome Smallpox", + "language": "English", + "version": "1.0.0", + "location": "Costa Rica", + "scope": "broad", + "category": "suspected", + "organization": "Caja Costarricense de Seguro Social", + "authors": [ + "Dirección de Desarrollo de Servicios de Salud" + ], + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T17:44:54Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Acute unexplained rash", + "attribute": "onset_date", + "operator": "<", + "value": "2022-03-15" + }, + { + "type": "criterion", + "name": "One or more of the following symptoms", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Headache" + }, + { + "type": "symptom", + "name": "Sudden onset fever", + "description": "Sudden onset fever (>38.5°C)" + }, + { + "type": "symptom", + "name": "Muscle pain" + }, + { + "type": "symptom", + "name": "Back pain" + }, + { + "type": "symptom", + "name": "Fatigue" + }, + { + "type": "symptom", + "name": "Lymphadenopathy" + } + ] + } + ] + } + ], + "exclusion_criteria": [ + { + "name": "Cause of ruling out acute exanthema", + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "diagnosis", + "name": "Chickenpox" + }, + { + "type": "diagnosis", + "name": "Shingles" + }, + { + "type": "diagnosis", + "name": "Measles" + }, + { + "type": "diagnosis", + "name": "Rubella" + }, + { + "type": "diagnosis", + "name": "Zika virus" + }, + { + "type": "diagnosis", + "name": "Dengue fever" + }, + { + "type": "diagnosis", + "name": "Chikungunya virus" + }, + { + "type": "diagnosis", + "name": "Common cold herpes" + }, + { + "type": "diagnosis", + "name": "Bacterial skin infections" + }, + { + "type": "diagnosis", + "name": "Disseminated gonococcal infection" + }, + { + "type": "diagnosis", + "name": "Primary or secondary syphilis" + }, + { + "type": "diagnosis", + "name": "Chancroid" + }, + { + "type": "diagnosis", + "name": "Lymphogranuloma venereum" + }, + { + "type": "diagnosis", + "name": "Granuloma inguinale" + }, + { + "type": "diagnosis", + "name": "molluscum contagiosum" + }, + { + "type": "diagnosis", + "name": "allergic reaction (for example, to plants)" + }, + { + "type": "diagnosis", + "name": "vesicular or papular rash" + } + ] + } + ], + "references": [ + { + "citation": "", + "url": "https://www.cendeisss.sa.cr/wp/wp-content/uploads/2024/04/Protocolo-Viruela-Simica.CCSS_.pdf" + } + ], + "status": "draft", + "human_readable_definition": "Persona de cualquier edad que se presenta con un exantema agudo inexplicable y que\npresentó uno o más de los siguientes signos o síntomas, con fecha de inicio posterior al 15\nde marzo de 2022:\n- Cefalea\n- Inicio súbito fiebre (>38,5°C)\n- Mialgia\n- Dolor de espalda\n- Astenia\n- Linfadenopatía\nY\npara los cuales se ha descartado, las siguientes y otras causas de exantema agudo que se\nmencionan a continuación: varicela, herpes zóster, sarampión, rubéola, zika, dengue,\nchikungunya, herpes simple, infecciones bacterianas de la piel, infección gonocócica\ndiseminada, sífilis primaria o secundaria, chancroide, linfogranuloma venéreo, granuloma\ninguinal, molusco contagioso, reacción alérgica (por ejemplo, a las plantas); y cualquier otra\ncausa común, localmente relevante de erupción vesicular o papular.\nNo es necesario tener resultados negativos de todas las enfermedades exantemáticas para\ndeterminar un caso como sospechoso.", + "target_public_health_threats": [ + "Smallpox" + ], + "keywords": [ + "Smallpox", + "North America" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/syphiliscongenitalandneonatal_greece.json b/machine_readable/json/syphiliscongenitalandneonatal_greece.json new file mode 100644 index 0000000000000000000000000000000000000000..00055d57c8cdaef78261d5d8e19ca7dafd82c3c4 --- /dev/null +++ b/machine_readable/json/syphiliscongenitalandneonatal_greece.json @@ -0,0 +1,99 @@ +{ + "title": "Open Syndrome Syphilis congenital and neonatal", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Greece", + "language": "English", + "organization": "National Public Health Organization", + "inclusion_criteria": [ + { + "type": "criterion", + "name": "Age < 2 years and at least 1 symptom", + "logical_operator": "AND", + "values": [ + { + "type": "demographic_criteria", + "name": "age", + "description": "< 2 years", + "attribute": "age", + "operator": "<=", + "value": 2, + "unit": "years" + }, + { + "type": "criterion", + "name": "With at least one of the following ten symptoms", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "hepatosplenomegaly" + }, + { + "type": "symptom", + "name": "mucocutaneous lesions" + }, + { + "type": "symptom", + "name": "flat warts" + }, + { + "type": "symptom", + "name": "persistent rhinitis" + }, + { + "type": "symptom", + "name": "jaundice" + }, + { + "type": "symptom", + "name": "Pseudoparalysis (due to periostitis and osteochondritis)" + }, + { + "type": "symptom", + "name": "Signs from the central nervous system" + }, + { + "type": "symptom", + "name": "anemia" + }, + { + "type": "symptom", + "name": "nephrotic syndrome" + }, + { + "type": "symptom", + "name": "reduced food intake" + } + ] + } + ] + } + ], + "references": [ + { + "url": "https://eody.gov.gr/wp-content/uploads/2022/04/orismoi-loimodon-nosimaton-20220413.pdf" + } + ], + "published_at": "2025-02-08T11:15:13Z", + "status": "draft", + "human_readable_definition": "Any infant aged 0–< 2 years with at least one of the following ten:\n– Hepatosplenomegaly\n– Mucocutaneous lesions\n– Flat warts\n– Persistent rhinitis\n– Jaundice\n– Pseudoparalysis (due to periostitis and osteochondritis)\n– Signs from the central nervous system\n– Anemia\n– Nephrotic syndrome\n– Reduced food intake", + "target_public_health_threats": [ + "Syphilis" + ], + "keywords": [ + "Syphilis", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/tuberculosis_europe_ecdc.json b/machine_readable/json/tuberculosis_europe_ecdc.json new file mode 100644 index 0000000000000000000000000000000000000000..53e2ea8d0a49a20c40d41f532e8b7245fe20b722 --- /dev/null +++ b/machine_readable/json/tuberculosis_europe_ecdc.json @@ -0,0 +1,57 @@ +{ + "title": "Open Syndrome Tuberculosis", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "language": "English", + "organization": "ECDC", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Signs, symptoms and/or radiological findings consistent with active tuberculosis in any site" + }, + { + "type": "criterion", + "logical_operator": "OR", + "values": [ + { + "type": "professional_judgment", + "name": "A clinician's decision to treat the person with a full course of anti-tuberculosis therapy" + }, + { + "type": "professional_judgment", + "name": "A case discovered post-mortem with pathological findings consistent with active tuberculosis that would have indicated anti-tuberculosis antibiotic treatment had the patient been diagnosed before dying" + } + ] + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T18:51:19Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "open_syndrome_version": "1.0.0", + "references": [ + { + "url": "https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0945&from=EN" + } + ], + "location": "Europe", + "status": "draft", + "human_readable_definition": "Any person with the following two:\n— Signs, symptoms and/or radiological findings consistent with active tuberculosis in any site\nAND\n— A clinician's decision to treat the person with a full course of anti-tuberculosis therapy\nOR\nA case discovered post-mortem with pathological findings consistent with active tuberculosis that would have indicated\nanti-tuberculosis antibiotic treatment had the patient been diagnosed before dying", + "target_public_health_threats": [ + "Tuberculosis" + ], + "keywords": [ + "Tuberculosis", + "Europe" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/viralhepatitis_turkey.json b/machine_readable/json/viralhepatitis_turkey.json new file mode 100644 index 0000000000000000000000000000000000000000..60669c14cbd6b431205826f673a4b535db84d873 --- /dev/null +++ b/machine_readable/json/viralhepatitis_turkey.json @@ -0,0 +1,75 @@ +{ + "title": "Open Syndrome Hepatitis A", + "description": "Viral hepatitis", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Turkey", + "language": "English", + "organization": "Turkish Ministry of Health's General Directorate of Public Health", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Sudden onset of abdominal pain, loss of appetite, weakness, nausea, vomiting" + }, + { + "type": "criterion", + "name": "At least one of the following clinical criteria", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 1 + ], + "values": [ + { + "type": "symptom", + "name": "Fever" + }, + { + "type": "symptom", + "name": "Jaundice" + }, + { + "type": "symptom", + "name": "Increased serum aminotransferase (ALT and AST), urobilinogen in urine" + } + ] + } + ] + } + ] + } + ], + "references": [ + { + "type": "web", + "url": "https://hsgm.saglik.gov.tr/depo/birimler/bulasici-hastaliklar-ve-erken-uyari-db/Dokumanlar/Sunumlar/TVHKP_Viral_Hepatitlerin_Bildirimi.pdf" + } + ], + "notes": [ + "It should be remembered that it may be mostly asymptomatic and/or anicteric" + ], + "status": "draft", + "human_readable_definition": "The presence of the following two clinical criteria.\n1. Sudden onset of abdominal pain, loss of appetite, fatigue, nausea, vomiting in an individual\n2. Presence of at least one of the following clinical criteria:\n• Fever\n• Jaundice\n• Elevated serum aminotransferases (ALT and AST) and increased levels of urobilinogen in urine\n(NOTE: It should be remembered that it may often be asymptomatic and/or anicteric.)", + "target_public_health_threats": [ + "Hepatitis A" + ], + "keywords": [ + "Hepatitis A", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/wheezeorapneaorcyanosis_pakistan.json b/machine_readable/json/wheezeorapneaorcyanosis_pakistan.json new file mode 100644 index 0000000000000000000000000000000000000000..394b3f84ed89c06391c0e3915ca4abbac6cc13ca --- /dev/null +++ b/machine_readable/json/wheezeorapneaorcyanosis_pakistan.json @@ -0,0 +1,73 @@ +{ + "title": "Open Syndrome Respiratory syncitial virus (RSV)", + "description": "Wheeze or apnea or cyanosis", + "scope": "specific", + "category": "suspected", + "version": "1.0.0", + "open_syndrome_version": "1.0.0", + "published_in": "https://opensyndrome.org", + "published_at": "2025-01-29T12:00:00Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "location": "Pakistan", + "language": "English", + "organization": "Hubert Department of Global Health", + "authors": [ + "Omer, Saad B. PhD", + "Bednarczyk, Robert PhD", + "Kazi, Momin MBBS", + "Guterman, L. Beryl MSPH", + "Aziz, Fatima MBBS", + "Allen, Kristen E. MPH", + "Yildirim, Inci PhD", + "Ali, S. Asad MBBS" + ], + "inclusion_criteria": [ + { + "type": "criterion", + "name": "Severe chest indrawing", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Severe chest indrawing" + }, + { + "type": "criterion", + "name": "Either cough or tachypnea", + "logical_operator": "OR", + "values": [ + { + "type": "symptom", + "name": "Cough" + }, + { + "type": "symptom", + "name": "Tachypnea" + } + ] + } + ] + } + ], + "references": [ + { + "citation": "Omer, Saad B. PhD*,†,‡,§; Bednarczyk, Robert PhD*,†,§; Kazi, Momin MBBS; Guterman, L. Beryl MSPH*; Aziz, Fatima MBBS; Allen, Kristen E. MPH*; Yildirim, Inci PhD†,‡; Ali, S. Asad MBBS. Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Testing in a Low Resource Population. The Pediatric Infectious Disease Journal 38(3):p e57-e59, March 2019. | DOI: 10.1097/INF.0000000000002159", + "url": "https://journals.lww.com/pidj/Fulltext/2019/03000/Assessment_and_Validation_of_Syndromic_Case.29.aspx" + } + ], + "notes": [ + "The syndromic screening definitions included:\n“wheeze or apnea or cyanosis” (the classic manifestation of RSV) (section Screening and Sample Selection, second paragraph)" + ], + "status": "draft", + "human_readable_definition": "severe chest indrawing with either cough or tachypnea", + "target_public_health_threats": [ + "Respiratory syncytial virus" + ], + "keywords": [ + "Respiratory syncytial virus", + "Asia" + ], + "definition_type": "case_definition" +} diff --git a/machine_readable/json/zika_paho.json b/machine_readable/json/zika_paho.json new file mode 100644 index 0000000000000000000000000000000000000000..2d88ba1e4f38b2e74f0344a75565d19ab4eb45a6 --- /dev/null +++ b/machine_readable/json/zika_paho.json @@ -0,0 +1,76 @@ +{ + "title": "Open Syndrome Zika", + "description": "", + "scope": "broad", + "category": "suspected", + "version": "1.0.0", + "location": "Americas", + "language": "English", + "organization": "PAHO", + "inclusion_criteria": [ + { + "type": "criterion", + "logical_operator": "AND", + "values": [ + { + "type": "symptom", + "name": "Rash", + "description": "Usually pruritic and maculopapular" + }, + { + "type": "criterion", + "logical_operator": "AT_LEAST", + "logical_operator_arguments": [ + 2 + ], + "values": [ + { + "type": "symptom", + "name": "Fever", + "attribute": "body_temperature", + "operator": ">=", + "value": 38.5, + "unit": "Celsius" + }, + { + "type": "symptom", + "name": "Conjunctivitis (non-purulent/hyperemic)" + }, + { + "type": "symptom", + "name": "Arthralgia" + }, + { + "type": "symptom", + "name": "Myalgia" + }, + { + "type": "symptom", + "name": "Peri-articular edema" + } + ] + } + ] + } + ], + "published_in": "https://opensyndrome.org", + "published_at": "2025-02-08T18:05:28Z", + "published_by": [ + "Open Syndrome Initiative" + ], + "open_syndrome_version": "1.0.0", + "references": [ + { + "url": "https://www.paho.org/en/topics/zika/zika-resources-case-definitions" + } + ], + "status": "draft", + "human_readable_definition": "Patient with rash* with two or more of the following signs or symptoms:\n\n fever, usually <38.5 ° C\n conjunctivitis (non-purulent/hyperemic)\n arthralgia\n myalgia\n peri-articular edema\n\n*usually pruritic and maculopapular", + "target_public_health_threats": [ + "Zika virus" + ], + "keywords": [ + "Zika virus" + ], + "definition_type": "case_definition" +}