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human_readable/txt/acuteflaccidparalysis_kenya

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+Suspected case: Any case with weakness or floppiness of the limbs of sudden onset not due to trauma in a child less than
+(Poliomyelitis)
+15 years of age, or any person of any age in whom a clinician suspects polio

human_readable/txt/arbovirosis_paraguay

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+Arbovirosis en
+IV - Vectoriales: arbovirosis y parasitosis
+Fiebre
+indiferenciada
+por picadura
+de mosquito.
+Síndrome febril
+agudo sin
+causa aparente
+A92.9 Universal
+Caso
+sospechoso de
+arbovirosis
+Clínica INDIVIDUAL
+INMEDIATO

human_readable/txt/avianinfluenzainhumans_australia

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+Clinical evidence
+An acute illness characterised by:
+1. Fever (>38°C) or history of fever AND one or more of; cough OR rhinorrhoea OR
+myalgia OR headache OR dyspnoea OR diarrhoea;
+OR
+2. Conjunctivitis
+OR
+3. Infiltrates or evidence of an acute pneumonia on a chest radiograph plus evidence
+of acute respiratory insufficiency (hypoxaemia, severe tachypnoea).

human_readable/txt/babesiosis_canada

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+Clinical evidence
+Clinical description:
+Babesiosis infections range in severity from asymptomatic to severe
+(occasionally fatal) depending on host and parasite factors. Most
+symptomatic infections caused by B. microti are mild and self-limiting,
+developing 1 to 4 weeks after the tick bite and 1 to 9 weeks after
+contamination of blood products. 1
+The salient features are fever and
+non-specific flu-like illness (malaise, fatigue, chills, sweats, and
+headache).
+Laboratory findings can include hemolytic anemia, thrombocytopenia.
+Patients who are asplenic, immunocompromised, elderly, or co-infected
+with other pathogens are at risk for severe disease. 1 2 3
+, ,
+Severe babesiosis is associated with a parasitemia of 10% or greater;
+hemolytic anemia; pulmonary, renal, and hepatic complications; and
+death.
+4
+Clinical criteria:
+Clinical criteria include fever and at least one of fatigue, chills, sweats,
+headache, anorexia, hemolytic anemia, or thrombocytopenia.

human_readable/txt/chlamydia_newzealand

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+Chlamydia Confirmed Probable Laboratory detection of Chlamydia trachomatis in a clinical specimen.
+Cases should be classified as:
+1. uncomplicated infection of the lower anogenital* tract
+* Includes urogenital and anorectal infection.
+2. 3. PID (pelvic inflammatory disease) or epididymitis
+infection of another site (eg, eye or pharynx)

human_readable/txt/cholera_colombia

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+Es el caso sospechoso que cumple con cualquiera de los siguientes criterios.
+Confirmación por laboratorio con cultivo de heces positivo para Vibrio cholerae O1 u O139 toxigénico.
+Confirmación por nexo epidemiológico:
+• Individuo que cumple con la definición de caso sospechoso, y tiene historia de contacto con un
+enfermo de cólera confirmado por laboratorio dentro de un período de cinco días
+• o antecedente de circulación activa del V. cholerae serotipo O1 u O139 toxigénico en el área de
+trabajo o residencia del caso.
+Se considera área de circulación activa aquella en donde el V. cholerae O1 u O139 toxigénico ha sido
+aislado de muestras biológicas o ambientales (agua, alimentos o restos de alimentos).

human_readable/txt/cholera_ghana

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+Suspected case:
+(rice water stool).
+In a patient age 5 years or more, severe dehydration or death from acute watery diarrhoea
+If there is a cholera epidemic, a suspected case is a person age 5 years or more with acute
+watery diarrhoea, with or without vomiting.

human_readable/txt/covid19_egypt

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+A
+Any one of the epidemiological
+history with any of the clinical
+features.
+epidemiological history:
+1. History of travel to or
+residence in communities
+where cases reported within
+the last 14 days.
+2. In contact with viral RNA
+positive people
+within the last 14 days.
+3. In contact with a patient who
+has fever or respiratory
+symptoms or from a
+community
+with confirmed cases reported
+within the last 14 days.
+B
+OR OR
+Asessing the presence of at
+least two of the following
+clinical features:
+1.Fever and/or respiratory
+symptoms.
+2.Imaging characteristics.
+CT scan is preferred, if not
+appicable do CXR
+3.Differential CBC findings:
+white blood cells is normal
+or decreased, with decreased
+lymphocytic count.
+C
+Severe Acute Respiratory
+Infection
+(SARI) with no other
+obvious cause.

human_readable/txt/covid19_philippines

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+A. Suspect Case
+1. A person who meets the clinical AND epidemiologic criteria:
+a. Clinical criteria
+i. Acute onset of fever AND cough OR
+ii. Acute onset of any of the three or more of the following signs or symptoms:
+fever, cough, general weakness, fatigue, headache, myalgia, sore throat,
+coryza, dyspnea, anorexia/nausea/vomiting/diarrhea, altered mental
+status
+b. Epidemiologic criteria
+i. Residing or working in an area with high risk of transmission of the virus:
+for example, closed residential settings and humanitarian settings such as
+camp and camp-like settings for displaced persons, any time within the 14
+days prior to symptoms onset; OR
+ii. Residing in or travel to an area with community transmission anytime within
+the 14 days prior to symptom onset OR
+iii. Working in health settings including within health facilities and within
+households, anytime within the 14 days prior to symptoms onset
+c. Patient with severe acute respiratory illness (SARI: acute respiratory infection
+with history of fever or measured fever > 38 C, and cough with onset within the
+last 10 days and who require hospitalization)

human_readable/txt/dengue_usa

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+ 
+Definition Purpose: Created by the CDC National Syndromic Surveillance Program (NSSP) for use with ED 
+data as part of the rapid reportables  project, which seeks to create queries for all National Notifiable 
+Diseases defined by the National Notifiable Diseases Surveillance System (NNDSS). This query is intended 
+to be a version 1 and may be further improved upon by the NSSP community of practice in the future. This 
+query is intended to be narrow and capture visits with specific terms to support greater monitoring and 
+actionable public health data. More complex and/or broader que ries may exist that more broadly capture 
+symptoms or travel-based terms. 
+ 
+New or Revised Definition: New Definition 
+ 
+Date Added to ESSENCE: July 2024 
+ 
+Definition Description:  Designed to capture emergency department visits associated with dengue infection. 
+ 
+Use-Cases for Definition: 
+☒ Case-finding   
+☒ Trend monitoring  
+☒ Early outbreak detection 
+ 
+Justification: No query definition exists for dengue virus infections. CDC wants to use syndromic data to 
+monitor trends. 
+ 
+Data Source  During Development : Emergency Department Visits. Chief Complaint Query Validation 
+dataset (CCQV) in ESSENCE. 
+ 
+Development Methods:  
+1. The CDC team used the NNDSS case definition of dengue virus Infections to identify diagnostic 
+codes (International Classification of Diseases, 9th & 10th Revision s (ICD-9-CM, ICD -10-CM), 
+SNOMED Clinical Terms (CT)) and chief complaint free text for syndrome development.  
+2. The codes and free text were then categorized as inclusion or exclusion terms. These terms were 
+formatted for querying in ESSENCE.    
+3. Text analysis was conducted on the initial query to find additional inclusion or exclusion terms.     
+4. The query was cross-checked internally by NSSP and by CDC subject matter experts as needed.  
+ 
+Validation Methods: This definition is part of the collection of definitions created by CDC NSSP for the rapid 
+reportables project. The rapid reportables project is led by the CDC NSSP team to create definitions for all 
+nationally reportable diseases. These definitions focus on chief complaint text and diagnostic codes of the 
+Dengue v1 
+Definition Factsheet & Technical Brief 
+ 
+Authors: Andzelika Rzucidlo, MPH 1,2, Dylan Johns, MS 1,3, Anna Frick, MPH 4, Sara Chronister, MPH 5, 
+David Atrubin6, Katharina L. van Santen, MSPH1,3 
+ 
+1 CDC Office of Public Health Data, Surveillance, and Technology (OPHDST), Immediate Office of the Director 
+(IOD), Integrated Monitoring Branch 
+2 InductiveHealth 
+3 ICF  
+4 Alaska Division of Public Health 
+5 Washington State Department of Health 
+6 Florida Department of Health 
+  
+Point of contact:  
+nssp@cdc.gov 
+ disease or its causative agents with no mention of symptoms. Select members of the Community of Practice 
+were then asked to review line -level results for their jurisdictions and provide feedback to ensure the 
+intended results of the definitions were met. 
+ 
+Definition Fields and Structure:  
+The Chief Complaint Discharge Diagnosis (CCDD) parsed field is used to query both the discharge 
+diagnosis codes and chief complaint free text. 
+• Inclusion based on dengue virus chief complaint free-text terms:  
+o The visit is included if it contains:  
+1. Chief complaints related to the pathogen name – (“dengue”) OR  
+• Inclusion based on ICD-10 discharge diagnosis codes related to dengue virus: 
+o The visit is included if it contains: 
+1. A discharge diagnosis code of Dengue fever [classical dengue] (A90) OR  
+2. A discharge diagnosis code of Dengue hemorrhagic fever (A91) OR  
+ 
+• Inclusion based on ICD-9 discharge diagnosis codes related to dengue virus: 
+o The visit is included if it contains: 
+1. A discharge diagnosis code of Dengue (061) OR 
+• Inclusion based on SNOMED discharge diagnosis code s related to active infection with dengue 
+virus: 
+o The visit is included if it contains: 
+1. A discharge diagnosis code of Dengue (38362002) OR 
+2. A discharge diagnosis code of severe Dengue (20927009) OR 
+3. A discharge diagnosis code of Dengue shock syndrome (409671005) OR 
+4. A discharge diagnosis code of myelitis caused by Dengue virus (866057003) OR 
+5. A discharge diagnosis code of Encephalitis caused by Dengue virus (1163101003) 
+• No exclusion terms or codes are used in this query.  
+ 
+Detailed Definition Components  
+Table 1. Inclusion and exclusion terms. 
+Variable 
+Type 
+Terms Description 
+Inclusions 
+Discharge 
+Diagnosis:  
+ICD-10-
+CM 
+A90 Dengue fever [classical dengue] 
+A91 Dengue hemorrhagic fever 
+Discharge 
+Diagnosis:  
+ICD-9-CM 
+061 Dengue 
+Discharge 
+Diagnosis: 
+SNOMED 
+concepts 
+38362002 Dengue 
+20927009 Severe dengue 
+409671005 Dengue shock syndrome 
+866057003 Myelitis caused by Dengue virus 
+1163101003 Encephalitis caused by Dengue virus 
+Chief 
+Complaint 
+Terms 
+Dengue 
+ 
+Table 2. ESSENCE syntax 
+^dengue^,or,^;A9[01]^,or,^;061;^,or,^;38362002;^,or,^;20927009;^,or,^;409671005;^,or,^;866057003;^,or
+,^;1163101003;^ 

human_readable/txt/denguefever_malaysia

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+Dengue Fever
+Acute onset of high grade fever of usually 2-5 days or more associated with two or more
+of the following: headache, retro-orbital pain, myalgia, arthralgia, rash and mild
+haemorrhagic manifestation (epistaxis, gums bleeding and petechiae).

human_readable/txt/diabetesmellitusnoinsulinodepedientetypeII_mexico

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+Caso sospechoso: Toda persona que reúna los siguientes criterios:
+poliuria, polidipsia y polifagia, más una glucemia plasmática casual mayor
+o igual a 200 mg/dl

human_readable/txt/diarrhea_pacificislands

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+3 or more loose or
+watery stools in 24 hrs

human_readable/txt/ebola_spain

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+Criterio clínico: Fiebre* (≥ 37,7 º C) con al menos otro síntoma compatible con la clínica de la enfermedad
+(cefalea intensa, vómitos, diarrea, dolor abdominal, dolor muscular o manifestación hemorrágica no
+explicada)
+* Para valorar la fiebre, se deberá tener en cuenta si está tomando antitérmicos, está en situación de
+inmunodepresión o cualquier otra situación que pueda afectar a la temperatura corporal, como son
+los niños, ancianos, etc. En los lactantes, especialmente en los menores de 3 meses, la fiebre puede no
+ser evidente y se deben valorar como criterio clínico los síntomas y signos de afectación sistémica.
+El criterio clínico en contactos en seguimiento por haber estado expuestos a un caso de EVE será fiebre o
+un cuadro clínico compatible con la enfermedad.

human_readable/txt/ebolaandmarburgvirus_who

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+Suspected case:2
+• any person, alive or dead, suffering or having suffered from sudden onset of high fever, and had
+contact with:
+o a suspected, probable, or confirmed Ebola case, or a dead or sick animal; OR
+• any person with sudden onset of high fever, AND at least three of the following symptoms:
+headache, lethargy, anorexia/loss of appetite, aching muscles or joints, stomach pain, difficulty
+swallowing, vomiting, difficulty breathing, diarrhoea, hiccups; OR
+• any person with inexplicable bleeding; OR
+• any sudden, inexplicable death.

human_readable/txt/equineencephalitis_guatemala

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+Definiciones de caso
+En Población humana
+• Caso sospechoso de encefalitis equina: Toda persona que presente fiebre de inicio
+repentino, asociada a uno o más de los siguientes signos neurológicos: cefalea,
+desorientación, temblores, convulsiones, parestesias, o algún tipo de parálisis,
+somnolencia, alteración del estado de conciencia, estupor, rigidez de nuca y que hayan
+visitado regiones con presencia de équidos (caballos, asnos y mulas) o bien, haber sufrido
+picaduras de mosquitos en áreas con muerte de estos équidos sospechosos de padecer
+encefalitis equina.

human_readable/txt/extremetemperaturescold_argentina

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+FRÍO: X31 (Exposición al frío natural excesivo)
+Efectos en salud asociados al frío extremo: Toda persona con antecedentes de
+exposición a frío extremo en circunstancia de Alerta Temprana por Temperatura
+Extrema (frío) del Servicio Meteorológico Nacional, y sintomatología clínica
+atribuible. Temperatura corporal igual o menor a 36 ºC y 2 o más de los siguientes
+síntomas, a saber:
+Signos y síntomas atribuibles: escalofríos, alteración del estado de conciencia, pulso
+débil, bradipnea, daño tisular local causado por el enfriamiento. Piel fría y roja en
+bebés.

human_readable/txt/extremetemperaturesheat_argentina

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+CALOR: X30 (Exposición al calor natural excesivo), T67 (Efectos del calor y la luz)
+Efectos en salud asociados al calor extremo: Toda persona con antecedentes de
+exposición a calor extremo en circunstancia de Alerta Temprana por Temperatura
+Extrema (calor) del Servicio Meteorológico Nacional, y sintomatología clínica
+atribuible - Temperatura corporal mayor o igual a 39 ºC y 2 o más de los siguientes
+síntomas, a saber:
+Signos y síntomas atribuibles: piel caliente, sudoración abundante en un primer
+momento o escasa, náuseas y/o vómitos, hipotensión, taquicardia y taquipnea,
+alteración del estado de conciencia, convulsiones, desmayo. En bebés: sudoración
+abundante, piel irritada por sudor.

human_readable/txt/humannipahvirus_bangladesh

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+Nipah like illness (Screening case definition) criteria:
+
+Fever (axillary temperature >38.5°C) or history of raised temperature prior to hospitalization AND any sign/symptom of brain pathology
+
+OR
+
+Fever (axillary temperature >38.5°C) or history of raised temperature prior to hospitalization AND any sign/symptom of lung pathology
+
+Suspected Nipah encephalitis criteria:
+Fever or history of fever (axillary temperature >38.5°C) AND evidence of acute brain pathology (e.g., altered mental status, new-onset seizures, or new neurological deficit either diffuse or localized to the brain)
+
+Suspected Nipah pneumonitis criteria:
+Onset of illness within the last seven days AND fever or history of fever (axillary temperature >38.5°C) AND severe shortness of breath (i.e., dyspnea that prevents the patient from walking unassisted for not more than ten steps) AND chest radiograph consistent with diffuse acute respiratory distress syndrome
+
+Probable Nipah infection criteria:
+History of Nipah encephalitis or pneumonitis AND established epidemiological link with at least one confirmed Nipah case but the absence of laboratory confirmation due to the patient's death
+
+Confirmed Nipah infection criteria:
+Laboratory confirmation of the infection; either by identification of anti-Nipah IgM via ELISA (Enzyme-linked immunosorbent assay) OR through identification of viral particles by qRT-PCR (quantitative reverse transcription polymerase chain reaction) with or without a history of Nipah encephalitis/pneumonitis

human_readable/txt/influenzalikeillness_africa_africacdc

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+Influenza-Like Illness (ILI) An acute respiratory infection with:
+•
+measured fever of ≥ 38 °C
+•
+and cough
+•
+with onset within the last 10 days

human_readable/txt/influenzalikeillness_brazil

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+2.1 DeFInIção De caso De sínDrome GrIpal ( sG):
+Indivíduo que apresente febre de início súbito, mesmo que referida, 
+acompanhada de tosse ou dor de garganta e pelo menos um dos seguin-
+tes sintomas: cefaleia, mialgia ou artralgia, na ausência de outro diagnós-
+tico específico.
+Em crianças menores de 2 anos de idade, considera-se também como 
+caso de síndrome gripal: febre de início súbito (mesmo que referida) e 
+sintomas respiratórios (tosse, coriza e obstrução nasal), na ausência de 
+outro diagnóstico específico.

human_readable/txt/intussusception_vietnam

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+Level 1 of diagnostic certainty
+Surgical criteria:
+The demonstration of invagination of the intestine at surgery;
+and/or
+Radiological criteria:
+The demonstration of invagination of the intestine by either air or liquid contrast enema;
+or
+The demonstration of an intra-abdominal mass by abdominal ultrasound with specific characteristic featuresb that is proven to be reduced by
+hydrostatic enema on post-reduction ultrasound;
+and/or
+Autopsy criteria:
+The demonstration of invagination of the intestine.

human_readable/txt/legionnairesdisease_uk

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+A case with clinical or radiological diagnosis of pneumonia but no
+microbiological evidence for confirmation of Legionella infection (above) is
+considered a probable case where the location and onset date(s) meet the
+outbreak-specific case definition for the exposure category (described in the
+section below).

human_readable/txt/leptospirosis_germany

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+Klinisches Bild
+Klinisches Bild einer akuten Leptospirose, definiert als mindestens eines der neun folgenden Kriterien:
+- ►allgemeine Krankheitszeichen,
+- Dyspnoe (Atemstörung),
+- ►Fieber,
+- Hämorrhagien (z.B. Lungenblutungen, subkonjunktivale Blutungen),
+- Husten,
+- Ikterus (Gelbsucht),
+- Meningitis oder Meningoenzephalitis,
+- Myokarditis (Herzmuskelentzündung),
+- ►Nierenfunktionsstörung
+ODER ►krankheitsbedingter Tod.

human_readable/txt/lujo_southafrica

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+A person with acute onset of fever
+>38.5°C, and at least three of the
+following signs and symptoms:
+ severe headache, myalgia,
+ diarrhea,
+ pharyngitis, abdominal pain,
+retrosternal chest pain,
+respiratory distress,
+ moderate thrombocytopenia,
+ increased AST and
+ leukocytosis,
+ proteinuria,
+ neurological signs or
+ sudden inexplicable death
+AND a likely epidemiological exposure
+including any of
+ contact with a suspected,
+probable or confirmed Lujo case,
+or
+ contact with a dead or sick
+animal especially rodents within
+the past 21 days.

human_readable/txt/malaria_nigeria

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+Unconfirmed severe malaria
+Any patient hospitalized with severe febrile disease with accompanying vital organ
+dysfunction diagnosed clinically.

human_readable/txt/measles_china

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+1.疑似病例
+发热,出疹(全身性斑丘疹)并伴有咳嗽,卡他性⿐炎或结膜炎症状之⼀者,或任何经过训练的卫⽣⼈员诊断为麻疹的病例均为疑似麻疹病例.

human_readable/txt/measles_ethiopia

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+National guidelines for measles surveillance are based on
+the WHO/-AFRO Measles and Rubella Surveillance guide-
+line, and define a suspected measles case as any person
+with a generalized maculopapular rash and fever plus one or
+more of the following: 1) cough, 2) coryza), or 3) conjunc-
+tivitis OR any person in whom a clinician suspects measles.

human_readable/txt/measles_india

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+11. Measles • A suspected measles case is any person with fever and maculopapular rash (non-vesicular)
+OR 
+• any person in whom a health worker or clinician suspects measles infection 
+**A probable rabid animal is a suspected rabid animal (as defined above) with additional histor y of a
+bite by another suspected / probable /confirmed rabid animal and/or is a suspected rabid animal that is

human_readable/txt/meningococcalmeningitis_mozambique

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+Caso suspeito: Uma pessoa com
+manifestação súbita de febre
+(>38,5º C no recto ou 38,0º C nas
+axilas), e pescoço rígido, con-
+sciência alterada ou quaisquer
+outros sinais meníngeos.

human_readable/txt/middleeastrespiratorysyndrome_saudiarabia

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+Children
+III. Acute febrile illness (T ≥380 C)
+Within 14 days before symptom
+and adults
+with/without respiratory symptoms
+onset:
+OR
+1. Exposure 4 to a confirmed case
+of MERS-CoV infection OR
+IV. Gastrointestinal symptoms
+2. Visit to a healthcare facility
+(diarrhea or vomiting), AND
+where MERS-CoV patients(s)
+leukopenia (WBC≤3.5x109 /L) or
+has recently (within 2 weeks)
+thrombocytopenia (platelets <
+been identified/treated OR
+150x109/L)
+3. Contact with dromedary
+camels5 or consumption of
+camel products (e.g. raw meat,
+unpasteurized milk, urine)

human_readable/txt/mpox_france

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+Patient suspect de mpox = signes cliniques évocateurs uniquement
+Un patient suspect d’infection par le virus Monkeypox est une personne présentant
+- Une éruption cutanée ou une ou des ulcérations de la muqueuse génitale, anale ou buccale,
+évocatrice de mpox
+- Isolée, ou précédée ou accompagnée d’une fièvre ressentie ou mesurée (>38°C),
+d’adénopathies ou d’une odynophagie.

human_readable/txt/mumps_ireland

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+Clinical criteria
+Any person with fever AND sudden onset of unilateral or bilateral tender swelling of the parotid or other salivary
+glands without other apparent cause. Mumps may also present as aseptic meningitis, encephalitis, hearing loss,
+orchitis, oophoritis, parotitis or other salivary gland swelling, mastitis or pancreatitis.

human_readable/txt/plague_peru

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+Caso Sospechoso de Peste:
+Paciente con presentación clínica compatible, y con antecedentes
+epidemiológicos consistentes de:
+• Exposición a humanos o animales infectados, y/o
+• Evidencia de picaduras de pulgas, y/o
+• Residencia o viaje a un área endémica conocida, dentro de los 10 días
+previos.

human_readable/txt/smallpox_costarica

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+Persona de cualquier edad que se presenta con un exantema agudo inexplicable y que
+presentó uno o más de los siguientes signos o síntomas, con fecha de inicio posterior al 15
+de marzo de 2022:
+- Cefalea
+- Inicio súbito fiebre (>38,5°C)
+- Mialgia
+- Dolor de espalda
+- Astenia
+- Linfadenopatía
+Y
+para los cuales se ha descartado, las siguientes y otras causas de exantema agudo que se
+mencionan a continuación: varicela, herpes zóster, sarampión, rubéola, zika, dengue,
+chikungunya, herpes simple, infecciones bacterianas de la piel, infección gonocócica
+diseminada, sífilis primaria o secundaria, chancroide, linfogranuloma venéreo, granuloma
+inguinal, molusco contagioso, reacción alérgica (por ejemplo, a las plantas); y cualquier otra
+causa común, localmente relevante de erupción vesicular o papular.
+No es necesario tener resultados negativos de todas las enfermedades exantemáticas para
+determinar un caso como sospechoso.

human_readable/txt/syphiliscongenitalandneonatal_greece

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+Κλινικά Κριτήρια
+Κάθε άτομο με μια τουλάχιστον από τις ακόλουθες κλινικές μορφές:
+Γριπώδης Συνδρομή (I.L.I.)
+– Αιφνίδια έναρξη συμπτωμάτων
+ΚΑΙ τουλάχιστον ένα από τα τέσσερα ακόλουθα συστηματικά συμπτώματα:
+– Πυρετός
+– Κακουχία
+– Κεφαλαλγία
+– Μυαλγία
+ΚΑΙ τουλάχιστον ένα από τα τρία ακόλουθα συμπτώματα από το αναπνευστικό:
+– Βήχας
+– Φαρυγγαλγία
+– Αναπνευστική δυσχέρεια
+Οξεία Λοίμωξη του αναπνευστικού (A.R.I)
+– Αιφνίδια έναρξη συμπτωμάτων
+ΚΑΙ τουλάχιστον ένα από τα ακόλουθα τέσσερα συμπτώματα από το αναπνευστικό:
+– Βήχας
+– Φαρυγγαλγία
+– Αναπνευστική δυσχέρεια
+– Καταρροή
+ΚΑΙ
+Εκτίμηση κλινικού ιατρού ότι πρόκειται για λοίμωξη του αναπνευστικού.

human_readable/txt/tuberculosis_europe_ecdc

@@ -0,0 +1,8 @@
+Clinical Criteria
+Any person with the following two:
+— Signs, symptoms and/or radiological findings consistent with active tuberculosis in any site
+AND
+— A clinician's decision to treat the person with a full course of anti-tuberculosis therapy
+OR
+A case discovered post-mortem with pathological findings consistent with active tuberculosis that would have indicated
+anti-tuberculosis antibiotic treatment had the patient been diagnosed before dying

human_readable/txt/viralhepatitis_turkey

@@ -0,0 +1,8 @@
+
+Aşağıdaki iki klinik kriterin görülmesidir.
+1. Bir kişide ani başlayan karın ağrısı, iştahsızlık, halsizlik, bulantı, kusma
+2. Aşağıdaki klinik kriterlerden en az birisinin olması
+• Ateş
+• Sarılık
+• Serum aminotransferaz (ALT ve AST), idrarda ürobilinojen düzeyinin yükselmesi
+(NOT: Çoğunlukla asemptomatik ve/veya anikterik seyredebileceği hatırlanmalıdır.)Hepatit A Epidemiyolojik Kriter

human_readable/txt/wheezeorapneaorcyanosis_pakistan

@@ -0,0 +1 @@
+wheeze or apnea or cyanosis

human_readable/txt/zika_paho

@@ -0,0 +1,8 @@
+Suspected case of Zika virus disease
+Patient with rash* with two or more of the following signs or symptoms:
+• fever, usually <38.5 ° C
+• conjunctivitis (non-purulent/hyperemic)
+• arthralgia
+• myalgia
+• peri-articular edema
+*usually pruritic and maculopapular

machine_readable/json/chlamydia_newzealand.json

@@ -0,0 +1,59 @@
+{
+  "title": "Open Syndrome Chlamydia",
+  "description": "Laboratory detection of Chlamydia trachomatis in a clinical specimen.",
+  "published_in": "https://opensyndrome.org",
+  "published_at": "2025-02-25T12:05:42Z",
+  "published_by": [
+    "Open Syndrome Initiative"
+  ],
+  "open_syndrome_version": "1.0.0",
+  "status": "draft",
+  "organization": "Institute of Environmental Science and Research",
+  "location": "New Zealand",
+  "language": "English",
+  "version": "1.0.0",
+  "category": "confirmed",
+  "scope": "broad",
+  "inclusion_criteria": [
+    {
+      "type": "diagnosis",
+      "name": "uncomplicated infection of the lower anogenital tract",
+      "description": "Anogenital includes urogenital and anorectal infection."
+    },
+    {
+      "logical_operator": "OR",
+      "type": "criterion",
+      "name": "PID (pelvic inflammatory disease) or epididymitis",
+      "values": [
+        {
+          "type": "diagnosis",
+          "name": "pelvic inflammatory disease",
+          "description": "PID"
+        },
+        {
+          "type": "diagnosis",
+          "name": "epididymitis"
+        }
+      ]
+    },
+    {
+      "name": "infection of another site (eg, eye or pharynx)",
+      "description": "eg, eye or pharynx",
+      "type": "diagnosis"
+    }
+  ],
+  "references": [
+    {
+      "url": "https://www.esr.cri.nz/media/0nadzkgc/sticasedefinitions.pdf"
+    }
+  ],
+  "human_readable_definition": "",
+  "target_public_health_threats": [
+    "Chlamydia"
+  ],
+  "keywords": [
+    "Chlamydia",
+    "Oceania"
+  ],
+  "definition_type": "case_definition"
+}

machine_readable/json/ebolaandmarburgvirus_who.json

@@ -0,0 +1,133 @@
+{
+  "title": "Open Syndrome Ebola Marburg Virus Cases",
+  "description": "",
+  "scope": "specific",
+  "category": "suspected",
+  "version": "1.0.0",
+  "published_in": "https://opensyndrome.org",
+  "published_at": "2025-02-08T18:26:37Z",
+  "published_by": [
+    "Open Syndrome Initiative"
+  ],
+  "open_syndrome_version": "1.0.0",
+  "location": "Global",
+  "language": "English",
+  "organization": "Open Syndrome Initiative",
+  "inclusion_criteria": [
+    {
+      "type": "criterion",
+      "logical_operator": "OR",
+      "values": [
+        {
+          "type": "criterion",
+          "logical_operator": "AND",
+          "name": "High fever and epidemiological history",
+          "values": [
+            {
+              "type": "symptom",
+              "name": "Sudden onset of high fever"
+            },
+            {
+              "type": "criterion",
+              "logical_operator": "OR",
+              "values": [
+                {
+                  "type": "epidemiological_history",
+                  "name": "Contact with a suspected, probable, or confirmed Ebola case"
+                },
+                {
+                  "type": "epidemiological_history",
+                  "name": "Contact with a dead or sick animal"
+                }
+              ]
+            }
+          ]
+        },
+        {
+          "type": "criterion",
+          "logical_operator": "AND",
+          "name": "High fever and at least 3 of the following symptoms",
+          "values": [
+            {
+              "type": "symptom",
+              "name": "Sudden onset of high fever"
+            },
+            {
+              "type": "criterion",
+              "logical_operator": "AT_LEAST",
+              "logical_operator_arguments": [
+                3
+              ],
+              "values": [
+                {
+                  "type": "symptom",
+                  "name": "Headache"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Lethargy"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Anorexia/loss of appetite"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Aching muscles or joints"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Stomach pain"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Difficulty swallowing"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Vomiting"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Difficulty breathing"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Diarrhea"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Hiccups"
+                }
+              ]
+            }
+          ]
+        },
+        {
+          "type": "symptom",
+          "name": "Inexplicable bleeding"
+        },
+        {
+          "type": "professional_judgment",
+          "name": "Sudden, inexplicable death"
+        }
+      ]
+    }
+  ],
+  "references": [
+    {
+      "url": "https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/ebola-and-marburg-virus-outbreak-toolbox"
+    }
+  ],
+  "status": "draft",
+  "human_readable_definition": "any person, alive or dead, suffering or having suffered from sudden onset of high fever, and had\ncontact with:\no a suspected, probable, or confirmed Ebola case, or a dead or sick animal; OR\n• any person with sudden onset of high fever, AND at least three of the following symptoms:\nheadache, lethargy, anorexia/loss of appetite, aching muscles or joints, stomach pain, difficulty\nswallowing, vomiting, difficulty breathing, diarrhoea, hiccups; OR\n• any person with inexplicable bleeding; OR\n• any sudden, inexplicable death.",
+  "target_public_health_threats": [
+    "Ebola and Marburg virus"
+  ],
+  "keywords": [
+    "Ebola",
+    "Marburg virus",
+    "WHO"
+  ],
+  "definition_type": "case_definition"
+}

machine_readable/json/lujo_southafrica.json

@@ -0,0 +1,124 @@
+{
+  "title": "Open Syndrome Lujo Hemorrhagic Fever",
+  "description": "Case definition for suspected Lujo viral hemorrhagic fever",
+  "scope": "specific",
+  "category": "suspected",
+  "version": "1.0.0",
+  "open_syndrome_version": "1.0.0",
+  "published_in": "https://opensyndrome.org",
+  "published_at": "2025-01-29T12:00:00Z",
+  "published_by": [
+    "Open Syndrome Initiative"
+  ],
+  "location": "South Africa",
+  "language": "English",
+  "organization": "National Institute for Communicable Diseases (NICD)",
+  "inclusion_criteria": [
+    {
+      "type": "criterion",
+      "logical_operator": "AND",
+      "values": [
+        {
+          "type": "symptom",
+          "name": "fever",
+          "description": ">38.5°C"
+        },
+        {
+          "type": "criterion",
+          "logical_operator": "AT_LEAST",
+          "logical_operator_arguments": [
+            3
+          ],
+          "values": [
+            {
+              "type": "symptom",
+              "name": "severe headache"
+            },
+            {
+              "type": "symptom",
+              "name": "myalgia"
+            },
+            {
+              "type": "symptom",
+              "name": "diarrhea"
+            },
+            {
+              "type": "symptom",
+              "name": "pharyngitis"
+            },
+            {
+              "type": "symptom",
+              "name": "abdominal pain"
+            },
+            {
+              "type": "symptom",
+              "name": "retrosternal chest pain"
+            },
+            {
+              "type": "symptom",
+              "name": "respiratory distress"
+            },
+            {
+              "type": "symptom",
+              "name": "moderate thrombocytopenia"
+            },
+            {
+              "type": "symptom",
+              "name": "increased AST"
+            },
+            {
+              "type": "symptom",
+              "name": "leukocytosis"
+            },
+            {
+              "type": "symptom",
+              "name": "proteinuria"
+            },
+            {
+              "type": "symptom",
+              "name": "neurological signs"
+            },
+            {
+              "type": "symptom",
+              "name": "sudden inexplicable death"
+            }
+          ]
+        },
+        {
+          "type": "criterion",
+          "logical_operator": "AT_LEAST",
+          "logical_operator_arguments": [
+            1
+          ],
+          "values": [
+            {
+              "type": "epidemiological_history",
+              "name": "contact with Lujo case",
+              "description": "Contact with a suspected, probable or confirmed Lujo case within past 21 days"
+            },
+            {
+              "type": "epidemiological_history",
+              "name": "contact with animal",
+              "description": "Contact with a dead or sick animal especially rodents within past 21 days"
+            }
+          ]
+        }
+      ]
+    }
+  ],
+  "references": [
+    {
+      "url": "https://www.nicd.ac.za/wp-content/uploads/2021/08/VIRAL-HAEMORRHAGIC-FEVER-DISEASES_Lujo-case-definition.pdf"
+    }
+  ],
+  "status": "draft",
+  "human_readable_definition": "A person with acute onset of fever\n>38.5°C, and at least three of the\nfollowing signs and symptoms:\n\uF0B7 severe headache, myalgia,\n\uF0B7 diarrhea,\n\uF0B7 pharyngitis, abdominal pain,\nretrosternal chest pain,\nrespiratory distress,\n\uF0B7 moderate thrombocytopenia,\n\uF0B7 increased AST and\n\uF0B7 leukocytosis,\n\uF0B7 proteinuria,\n\uF0B7 neurological signs or\n\uF0B7 sudden inexplicable death\nAND a likely epidemiological exposure\nincluding any of\n\uF0B7 contact with a suspected,\nprobable or confirmed Lujo case,\nor\n\uF0B7 contact with a dead or sick\nanimal especially rodents within\nthe past 21 days.",
+  "target_public_health_threats": [
+    "Lujo hemorrhagic fever"
+  ],
+  "keywords": [
+    "Lujo hemorrhagic fever",
+    "Africa"
+  ],
+  "definition_type": "case_definition"
+}

machine_readable/json/measles_china.json

@@ -0,0 +1,79 @@
+{
+  "title": "Open Syndrome Measles",
+  "description": "",
+  "scope": "broad",
+  "category": "suspected",
+  "version": "1.0.0",
+  "open_syndrome_version": "1.0.0",
+  "published_in": "https://opensyndrome.org",
+  "published_at": "2025-02-27T17:48:51Z",
+  "published_by": [
+    "Open Syndrome Initiative"
+  ],
+  "status": "draft",
+  "language": "English",
+  "organization": "China CDC",
+  "location": "China",
+  "inclusion_criteria": [
+    {
+      "type": "criterion",
+      "name": "Symptoms or professional diagnosis",
+      "logical_operator": "OR",
+      "values": [
+        {
+          "type": "criterion",
+          "logical_operator": "AND",
+          "values": [
+            {
+              "type": "symptom",
+              "name": "Fever"
+            },
+            {
+              "type": "symptom",
+              "name": "Rash (maculopapular rash)"
+            },
+            {
+              "type": "symptom",
+              "name": "Cough"
+            },
+            {
+              "type": "criterion",
+              "logical_operator": "AT_LEAST",
+              "logical_operator_arguments": [
+                1
+              ],
+              "values": [
+                {
+                  "type": "symptom",
+                  "name": "Catarrhal fever"
+                },
+                {
+                  "type": "symptom",
+                  "name": "Conjunctivitis"
+                }
+              ]
+            }
+          ]
+        },
+        {
+          "type": "professional_judgment",
+          "name": "Measles diagnosed by any trained health worker"
+        }
+      ]
+    }
+  ],
+  "references": [
+    {
+      "url": "https://www.chinacdc.cn/jkyj/crb2/yl/mz/jswj_mz/202409/t20240909_299153.html"
+    }
+  ],
+  "human_readable_definition": "未进行流行病学调查或完成调查前失访或死亡的病例,实验室检测结果为阴性或无实验室诊断结果的临床报告病例,且与实验室确诊病例没有流行病联系.",
+  "target_public_health_threats": [
+    "Measles"
+  ],
+  "keywords": [
+    "Measles",
+    "Asia"
+  ],
+  "definition_type": "case_definition"
+}