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dbcffef4-237b-4da7-81be-685af2222372
Hypothalamic glutamate neurotransmission is crucial to energy balance.
[{"id": "11886686", "score": 1}, {"id": "25007443", "score": 1}]
540
test
b949b101-7b19-462c-843e-faaab940bc23
The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events.
[{"id": "11335781", "score": 1}]
1278
test
e4c4100e-dcea-4730-91d8-77533ca2b876
Occupancy of ribosomes by IncRNAs mirror 5 0-UTRs
[{"id": "8426046", "score": 1}]
880
test
4f7cfad8-909b-4850-a96c-41349cfa7dba
Hypoglycemia increases the risk of dementia.
[{"id": "13282296", "score": 1}]
539
test
d2ae12c9-fc0a-4efd-9ecc-321753cd8414
Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake.
[{"id": "3553087", "score": 1}]
300
test
6e0531cd-687a-42d5-8a94-40dcd12f2442
Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.
[{"id": "4456756", "score": 1}]
1121
test
e0b67953-17c0-49a9-a8a3-ec50d2d5f041
Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls.
[{"id": "1834762", "score": 1}]
721
test
f6d6bf13-f46a-4ff1-b87f-fafa6ae3273b
Cold exposure increases BAT recruitment.
[{"id": "970012", "score": 1}]
268
test
46fda99b-6ae5-47f8-aa64-6174aac3eeea
The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins.
[{"id": "12428814", "score": 1}, {"id": "27731651", "score": 1}, {"id": "4406819", "score": 1}]
1274
test
d071938e-bf66-43e4-a8aa-78ea7441f375
Occupancy of ribosomes by IncRNAs do not make functional peptides.
[{"id": "8426046", "score": 1}]
879
test
87cf003e-9336-4cb3-81df-55238017a34b
Hypocretin neurones induce panicprone state in rats.
[{"id": "16056514", "score": 1}]
536
test
e70ab356-d9f0-4b36-99fa-79a2eb1d2d03
Suboptimal nutrition is not predictive of chronic disease
[{"id": "13770184", "score": 1}]
1110
test
062bdb4b-0214-436b-94f4-be395af1a0ee
ADAR1 binds to Dicer to cleave pre-miRNA.
[{"id": "5953485", "score": 1}]
49
test
2f49c01e-1d83-413f-8876-5ee1b59686f9
Cell autonomous sex determination in somatic cells occurs in Passeriformes.
[{"id": "4388470", "score": 1}]
236
test
55c5a0fb-a71d-4a05-b5ed-90c608b345a5
Low nucleosome occupancy correlates with low methylation levels across species.
[{"id": "17587795", "score": 1}]
718
test
329e3472-66ad-470e-ac28-25ec429089a6
Obesity is determined solely by environmental factors.
[{"id": "1180972", "score": 1}, {"id": "19307912", "score": 1}, {"id": "27393799", "score": 1}, {"id": "29025270", "score": 1}, {"id": "3315558", "score": 1}]
873
test
c6ac0230-7a0b-445b-a907-4dae0d81747b
The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.
[{"id": "11041152", "score": 1}]
1273
test
1fb3ca97-8d25-4164-87b4-e93e72b0bfaa
Hypertension is frequently observed in type 1 diabetes patients.
[{"id": "39368721", "score": 1}]
535
test
4a9293ed-b886-4165-ae46-7a130cf4b63f
Subcutaneous fat depots undergo extensive browning processes after cold exposure.
[{"id": "20532591", "score": 1}]
1107
test
6e9a9120-3f71-4c0e-ad4d-da2be432b2ff
Low expression of miR7a exerts a biological function in testis.
[{"id": "18421962", "score": 1}]
716
test
76f981e4-0a67-4dcd-a7b9-7d616b9d298d
Cellular aging closely links to an older appearance.
[{"id": "14079881", "score": 1}]
239
test
dd6c9a06-73cb-461d-8826-3eaa3eea7e54
Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin.
[{"id": "3898784", "score": 1}]
1104
test
3bceb69a-7682-4b60-b44f-f33b3eb05a7c
Hyperfibrinogenemia increases rates of femoropopliteal bypass thrombosis.
[{"id": "12991445", "score": 1}]
533
test
8af91e26-0978-40fa-98ea-36c5d1e258a0
The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells.
[{"id": "17081238", "score": 1}]
1272
test
f62bc712-5f39-4319-905a-d425ee5598c8
Obesity decreases life quality.
[{"id": "195689316", "score": 1}]
870
test
35e0a016-a3af-4a24-9afb-04dfa0d97f6b
Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is effective at treating KRAS mutant tumors.
[{"id": "4961038", "score": 1}, {"id": "14241418", "score": 1}, {"id": "14819804", "score": 1}]
275
test
3ce2e4e7-f24d-4264-bb1e-0592c14f5ca4
Low expression of miR7a does represses target genes and exerts a biological function in ovaries.
[{"id": "18421962", "score": 1}]
715
test
a7f6a4ad-37b2-4474-94a1-9b5cb4d60d27
Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.
[{"id": "1122279", "score": 1}, {"id": "10697096", "score": 1}]
261
test
5f7c3c80-dd91-4966-a2c8-d3325ac35bc4
The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI.
[{"id": "13768432", "score": 1}]
1271
test
41682b25-6bcd-4af7-ba8a-4ebeb1bbe483
ALDH1 expression is associated with poorer prognosis in breast cancer.
[{"id": "45638119", "score": 1}]
53
test
0371e67f-7e31-4dd2-8b09-0f34b16f9093
Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis.
[{"id": "12991445", "score": 1}]
532
test
22b3ea2c-09fb-474c-b3a5-3a6f9275c59f
Normal expression of RUNX1 has tumor-promoting effects.
[{"id": "1982286", "score": 1}]
859
test
abe97dc6-9fe5-47a1-b461-edf2e59015c1
Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax.
[{"id": "5476778", "score": 1}]
528
test
135897a2-07f2-4fcf-a26b-6b221a1b6d18
Localization of PIN1 in the roots of Arabidopsis does not require VPS9a
[{"id": "4350400", "score": 1}]
702
test
90972af5-3691-48a6-956f-7d07a4f62b1a
Statins increase blood cholesterol.
[{"id": "7662206", "score": 1}]
1100
test
1ca921fc-f02c-4a0e-b612-88255feeb185
Chenodeosycholic acid treatment increases whole-body energy expenditure.
[{"id": "1568684", "score": 1}]
248
test
56100b13-9a5c-43ee-a8d6-edd044cf4e8b
The risk of male prisoners harming themselves is ten times that of female prisoners.
[{"id": "13900610", "score": 1}]
1270
test
478ab5e9-a06b-41ee-9b8b-15021f8d8457
Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment.
[{"id": "13843341", "score": 1}]
852
test
faee91fe-28e9-446f-bc7a-517c37dcbc07
Birth-weight is positively associated with breast cancer.
[{"id": "16322674", "score": 1}, {"id": "27123743", "score": 1}, {"id": "23557241", "score": 1}, {"id": "17450673", "score": 1}]
179
test
880fb7f7-c803-452c-9876-4c428e16b9b2
Statins decrease blood cholesterol.
[{"id": "7662206", "score": 1}]
1099
test
d3772d41-15a6-499b-8c25-647c10218645
Localization of PIN1 in the Arabidopsis embryo does not require VPS9a
[{"id": "4350400", "score": 1}]
700
test
4b0181b0-f9b7-4481-b405-9637e59ab8c6
Cells undergoing methionine restriction may activate miRNAs.
[{"id": "2251426", "score": 1}]
238
test
a81494ba-2651-44ee-92e9-011d45dbe7c5
The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.
[{"id": "37480103", "score": 1}]
1266
test
22820658-2bed-4739-beb8-acb8870a719f
Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils.
[{"id": "17741440", "score": 1}]
845
test
42d1ee73-abeb-4dc3-a7f8-72a426d1564a
Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.
[{"id": "10582939", "score": 1}]
142
test
644b606f-f2dd-4c16-8ed1-e054bc883c3f
New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.
[{"id": "16787954", "score": 1}]
847
test
b4c84abe-069c-4cb7-8666-50e98493db39
Cell autonomous sex determination in somatic cells does not occur in Galliformes.
[{"id": "4388470", "score": 1}]
233
test
b4e5b6ce-64a9-4f0f-ba9c-b5d53249230e
Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.
[{"id": "3863543", "score": 1}]
527
test
631f4f58-7522-4243-86ee-1d295984e603
Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding.
[{"id": "17628888", "score": 1}]
1089
test
6ed08f03-446c-4d16-9404-73d58a69d64c
Leuko-reduced blood reduces infectious complications in red blood cell transfusion.
[{"id": "24088502", "score": 1}]
693
test
513f9772-6104-432f-b208-5e9ec48561b3
The repair of Cas9-induced double strand breaks in human DNA is error-prone.
[{"id": "44172171", "score": 1}]
1262
test
be5a9e1d-20f9-44ab-a112-3c85016e2217
Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.
[{"id": "13639330", "score": 1}]
525
test
da2ba8f9-d8e6-45da-a21b-d49aa1c6c429
Arterioles have a larger lumen diameter than venules.
[{"id": "8290953", "score": 1}]
128
test
0cdcb009-405f-45d4-b1a1-d2ec27d90da4
Silencing of Bcl2 is important for the maintenance and progression of tumors.
[{"id": "37549932", "score": 1}]
1088
test
24f4f15a-ff40-4821-b0b4-cbf1bed9573c
Leukemia associated Rho guanine nucleotide-exchange factor represses RhoA in response to SRC activation.
[{"id": "10991183", "score": 1}]
691
test
55ebc309-d7b7-4125-b057-760781ec724a
High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI).
[{"id": "34873974", "score": 1}]
521
test
7dd13202-d246-4652-9a31-1624a5107be7
Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles.
[{"id": "1469751", "score": 1}]
839
test
aebc29f3-e2ac-45e6-b16f-a385c7cb855d
Leuko-increased blood increases infectious complications in red blood cell transfusion.
[{"id": "24088502", "score": 1}]
692
test
ed67ed2a-3a6c-4fe2-be27-9aa2c5efa0f4
Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.
[{"id": "39281140", "score": 1}]
1086
test
c47a16a4-dee5-4954-a985-9d68dd2655ea
Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae.
[{"id": "10874408", "score": 1}]
294
test
5c605c23-5691-4dc8-a248-4f8f18588a04
The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up.
[{"id": "24341590", "score": 1}]
1259
test
ad3777d2-e3ee-427f-b4d6-e9499baa2e4f
CX3CR1 on the Th2 cells impairs T cell survival
[{"id": "21366394", "score": 1}]
216
test
c4d38333-738c-4137-b5b0-808513d4159a
Autophagy declines in aged organisms.
[{"id": "1084345", "score": 1}]
148
test
c9353edd-a38d-46f1-854d-26002fc365ce
The one-child policy has been successful in lowering population growth.
[{"id": "7662395", "score": 1}]
1245
test
af29b2fa-5cca-4023-ac07-c1865e61ce6b
NR5A2 is important in development of endometrial tissues.
[{"id": "15928989", "score": 1}]
837
test
cf572920-365a-42b0-b7a2-da6a1016bb2d
High levels of copeptin decrease risk of diabetes.
[{"id": "15663829", "score": 1}]
517
test
7851bb9a-ad99-4506-95f5-6e39593bfe65
The myocardial lineage develops from cardiac progenitors of mesodermal origin.
[{"id": "4427392", "score": 1}]
1241
test
86040f8d-5538-44ba-aa9b-4003cdf06763
High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).
[{"id": "29564505", "score": 1}]
516
test
ceac94fc-02a7-4be7-a192-b9d1c7b39bfc
Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src.
[{"id": "38485364", "score": 1}, {"id": "6969753", "score": 1}, {"id": "17934082", "score": 1}, {"id": "16280642", "score": 1}, {"id": "12640810", "score": 1}]
133
test
7908c00b-b698-4c01-8b1a-c3ffd57fb78d
Ribosomopathies have a low degree of cell and tissue specific pathology.
[{"id": "12486491", "score": 1}]
1049
test
ea688e04-e1c2-43c2-a3a1-b4a668b8b89a
DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region.
[{"id": "4388470", "score": 1}]
303
test
a4b67023-93cc-4e04-a5ab-7cf1ea3b1f5c
Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells.
[{"id": "4942718", "score": 1}]
684
test
590dc8e1-b50a-47c7-b11a-a5351b3cc678
S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases.
[{"id": "20381484", "score": 1}]
1062
test
b70dd43b-9c13-4a08-b9ea-40a167a11264
Less than 10% of the gabonese children with Schimmelpenning-Feuerstein-Mims syndrome (SFM) had a plasma lactate of more than 5mmol/L.
[{"id": "18750453", "score": 1}]
690
test
abe2e81f-d3e4-478c-9420-5cb0a5b65440
NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.
[{"id": "5483793", "score": 1}]
834
test
bdd1121c-4e11-4bac-9f10-d6aa190fe095
Chenodeosycholic acid treatment reduces whole-body energy expenditure.
[{"id": "1568684", "score": 1}]
249
test
cc23b4ca-b099-4aed-adf8-4e49db831f0b
The minor G allele of FOXO3 is related to more severe symptoms of Crohn's Disease.
[{"id": "13905670", "score": 1}]
1232
test
e69105ba-d0d6-44e8-8168-b55ab038e055
High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.
[{"id": "16256507", "score": 1}]
514
test
f8c09952-a6e3-4b14-8cb4-4d287c5397f7
NFAT4 activation requires IP3R-mediated Ca2+ mobilization.
[{"id": "30303335", "score": 1}]
832
test
0d74188b-a00c-49f6-a1ad-4fa77c7e6cc2
Cataract and trachoma are the primary cause of blindness in Southern Sudan.
[{"id": "10536636", "score": 1}]
232
test
f85740f0-5cc0-404a-8ae2-cd95aab4cab1
Deleting Raptor reduces G-CSF levels.
[{"id": "2014909", "score": 1}]
324
test
e2e2fdd2-e1e2-41fd-ae2a-eecdc2338fa8
LDL cholesterol has no involvement in the development of cardiovascular disease.
[{"id": "2095573", "score": 1}]
674
test
d3988624-c0a3-40d1-a0aa-12cb6895f338
Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes.
[{"id": "25254425", "score": 1}, {"id": "16626264", "score": 1}]
1041
test
a2b10f0d-6fa8-4e1f-9659-f474b682d50f
p16INK4A accumulation is linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).
[{"id": "17717391", "score": 1}]
1395
test
338bdd51-4a6c-4cc7-b926-03138d6846cd
The loss of the TET protein functions may have dire biological consequences, such as myeloid cancers.
[{"id": "13777138", "score": 1}]
1226
test
e52d94e6-a308-4cae-ba03-98ffb5ac5d34
NF2 (Merlin) prevents phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila.
[{"id": "1897324", "score": 1}]
831
test
d3de4679-ceb7-4827-a517-7b12d86cac7a
High cardiopulmonary fitness causes increased mortality rate.
[{"id": "13230773", "score": 1}]
513
test
64e8ae6b-426b-4a8b-aab5-0901087a46c3
Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis.
[{"id": "4942718", "score": 1}]
237
test
56685cc7-f005-4954-bb80-943934c9178f
mTORC2 regulates intracellular cysteine levels through xCT inhibition.
[{"id": "23895668", "score": 1}]
1389
test
84a5fde0-44d6-47b9-97e8-f36def9e0071
Ivermectin is used to treat onchocerciasis.
[{"id": "1215116", "score": 1}]
660
test
825ab590-bd30-4f3c-8250-78ab8ec6e73e
Hematopoietic Stem Cell purification reaches purity rate of up to 50%.
[{"id": "13980338", "score": 1}]
508
test
a4eefc3c-5c24-46cf-a10f-ca0f9d702b4e
NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases.
[{"id": "1897324", "score": 1}]
830
test
6969fd2d-54b3-4a67-81c1-be5887f78344
Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries.
[{"id": "3067015", "score": 1}]
230
test
c5cc5fa2-e786-4f31-b11e-45738d33751f
Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.
[{"id": "13923140", "score": 1}, {"id": "13940200", "score": 1}, {"id": "11899391", "score": 1}]
1029
test
d99a220f-de65-4f15-9c37-fe42bf6eca45
The locus rs647161 is associated with colorectal carcinoma.
[{"id": "9650982", "score": 1}]
1225
test
523517e5-a19e-4a56-b470-10d26d93d816
A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection.
[{"id": "13734012", "score": 1}]
48
test
ba46c799-bdf8-46aa-b0db-b05c52b03f4c
Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events.
[{"id": "7873737", "score": 1}, {"id": "5884524", "score": 1}]
343
test
11175290-98d2-40c7-b6e0-b455007434a3
cSMAC formation enhances weak ligand signalling.
[{"id": "306006", "score": 1}]
1385
test
29eb0a7d-923e-4505-87cf-f251cf59e050
Recurrent mutations occur frequently within CTCF anchor sites adjacent to oncogenes.
[{"id": "5373138", "score": 1}]
1024
test
74391f62-b32a-402e-9e9c-3c718541ff32
Ivermectin is used to treat lymphatic filariasis.
[{"id": "1215116", "score": 1}]
659
test