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<urn:uuid:00000a6f-3469-4a08-abd9-41af03fc6ee5>
The evidence favors rejection of a causal relation between DT, Td, or tetanus toxoid and encephalopathy (acute or chronic). Seizures are neurologic events that may occur with or without the loss of consciousness and can include a variety of sensory experiences (e.g., auditory seizures), motor manifestations (e.g., foca...
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<urn:uuid:00000e01-281e-4d41-b846-84ab2d191b79>
To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Les...
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<urn:uuid:00001f84-fe21-4e17-9da4-70c5b8dd55ea>
Vomiting is characterized by the contents of the stomach being ejected. Chronic vomiting, meanwhile, is marked by the long duration or frequent recurrence of said vomiting. Diseases of the stomach and upper intestinal tract are the primary cause for this type of vomiting. Secondary implications are diseases of other or...
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<urn:uuid:00002662-1bb4-4d26-9cae-9603001adf06>
Treatment of diabetes (Proceedings) There are many different types of insulin that vary with species of origin and with chemical modifications and formulations that affect onset and duration of action. Porcine insulin, which is identical to canine insulin in its amino acid structure, is available for use in dogs in som...
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<urn:uuid:00004351-492d-4cbd-8e37-be0742f3952a>
Photo Credit: Getty Images Medical advances have transformed the treatment of rheumatoid arthritis (RA), a chronic inflammatory condition in which the immune system attacks the synovium (a thin layer of soft tissue) that lines the joints, causing swelling, pain and, in severe cases, immobility and deterioration of the ...
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<urn:uuid:000050df-0997-451f-991f-006fd9cce543>
Environmental Influences on Neurodevelopment: An Overview This essay is in response to the question: How does the environment influence brain development? What are the exposures of greatest concern? What is the latest science and how can we translate that science into protective public health policy? Brain development ...
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<urn:uuid:0000544a-812e-41b6-ad75-0a741d424382>
Based on studies conducted in laboratories, animals, and people, ginkgo is used for the following: Dementia and Alzheimer's disease Ginkgo is widely used in Europe for treating dementia. At first, doctors thought it helped because it improves blood flow to the brain. Now more study suggests it may protect nerve cells t...
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<urn:uuid:00006c01-702c-4d8c-be07-89b445090697>
UTSA research team closer to tularemia therapy By Christi Fish Public Affairs Specialist (Feb. 3, 2009)--Researchers are closer to developing therapies to combat the deadly tularemia infection, according to a study published Feb. 2 in the Proceedings of the National Academy of Sciences Early Edition. - La Prensa Founda...
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<urn:uuid:00008344-8c31-438b-af0c-00225f12c411>
This information is for reference purposes only. It was current when produced and may now be outdated. Archive material is no longer maintained, and some links may not work. Persons with disabilities having difficulty accessing this information should contact us at: https://info.ahrq.gov. Let us know the nature of the ...
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<urn:uuid:000090ec-a997-4e13-916a-367927756c3b>
For decades, neurologists have known that a diet high in fat and extremely low in carbohydrates can reduce epileptic seizures that resist drug therapy. But how the diet worked, and why, was a mystery — so much so that in 2010, The New York Times Magazine called it "Epilepsy's Big, Fat Miracle." Now, researchers at Dana...
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<urn:uuid:00009892-85af-4f51-a9db-46de9ffa0f42>
Issue Date: September 22, 2008 "IN THE 1980s, if you could give people three months with a monotherapy, it was a big deal," says Roger J. Pomerantz, a doctor who has worked in the HIV arena since 1982. The first anti-HIV drug, GlaxoSmithKline's zidovudine (AZT), was approved in 1987. In the early 1990s, more drugs emer...
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<urn:uuid:0000a941-1031-46fc-9b5e-702511a46316>
The parasitic skin disease tungiasis (caused by the flea Tunga penetrans) affects resource-poor communities in Latin America, the Caribbean and sub-Saharan Africa. Prevalences in endemic areas are high, and severe pathology occurs commonly. However, risk factors for infestation have never been assessed in Africa. Metho...
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<urn:uuid:0000a98b-6bd2-4827-ab2e-5e6a4a60abc1>
Most of us are acutely aware of the limitations of current in silico methods for predicting genes in the human genome. In the May issue of Nature Biotechnology, Saurabh Saha and colleagues at the Johns Hopkins Medical Institutions describe an experimental approach for gene discovery and genome annotation (Nature Biotec...
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<urn:uuid:0000afdc-0b37-4708-abe2-ab64ad0c94ce>
Non-protein-coding RNAs (ncRNAs) are increasingly being recognized as having important regulatory roles. Although much recent attention has focused on tiny 22- to 25-nucleotide microRNAs, several functional ncRNAs are orders of magnitude larger in size. Examples of such macro ncRNAs include Xist and Air, which in mouse...
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<urn:uuid:0000b217-8235-4d52-bec4-01a82771680e>
Controlling High Cholesterol High cholesterol is a well-known risk factor in heart disease. This waxy, fat-like substance comes from the diet, but is primarily made by the liver, and is an essential component of cell membranes. The body also uses it to produce hormones and vitamin D. Cholesterol is carried through the ...
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<urn:uuid:0000b276-e632-46d8-be38-25854a7eda1b>
Third molars or wisdom teeth, as they are more commonly known, are the teeth which are most often missing, impacted and with altered morphology. Advances in dental anthropology states that there is a reduction in the number of teeth and size of jaws on evolutionary basis for the past 100000 years. Third incisors, third...
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<urn:uuid:0000f243-598a-4f25-b947-5bd1ecdbe367>
Investigators at Harvard-affiliated Massachusetts General Hospital (MGH) may have found a way to solve a problem that has plagued ligand-mimicking integrin inhibitors, a group of drugs that have the potential to treat conditions ranging from heart attacks to cancer metastasis. Integrins are receptor proteins found on t...
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<urn:uuid:0001274c-64da-48b0-8a6a-388126acbf89>
A consortium of researchers has detailed the activity of a novel drug compound that kills multiple HIV strains via a unique mechanism of action. The discovery brings with it hope in using this compound in both topical and systemic applications for HIV therapy. The compound is just one belonging to the Ceragenin (CSA) f...
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<urn:uuid:00012d91-20ed-4e71-a046-f89176a0283d>
The first entire genome of an Irish individual has been sequenced. The sequence is reported in BioMed Central's open access journal, Genome Biology and provides insight into the evolutionary history of this distinct lineage. Led by Professor Brendan Loftus, the research team from UCD Conway Institute used data from a p...
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<urn:uuid:00013106-b91c-4831-983e-5d784f99571c>
Foodborne, waterborne and soilborne diseases WHO concluded an agreement with Swiss Disaster Relief to provide technical assistance in epidemic diarrhoea control and preparedness, and established links with other agencies and organizations working in the same field. For instance, collaboration began with the Internation...
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<urn:uuid:00013a08-1f43-4405-a21a-c39c9af5e274>
- National Center for Health Statistics 3311 Toledo Rd Hyattsville, MD 20782 - 1 (800) 232-4636 - Contact CDC–INFO NCHS Health E-Stat Sleep Duration as a Correlate of Smoking, Alcohol Use, Leisure-Time Physical Inactivity, and Obesity Among Adults: United States, 2004-2006 by Charlotte A. Schoenborn, M.P.H., and Patric...
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<urn:uuid:000145ea-dd41-4edc-aaf0-6a83c49e8afd>
Author Affiliations: Division of Pediatric Neurology, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor. A substantial minority of children with epilepsy have continued seizures despite adequate trials of standard antiseizure medications. To maximize seizure control and thereby optim...
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<urn:uuid:000145fe-7507-4ac4-8c9e-d813e78c6a4b>
Treatment Option Overview Key Points for This Section - There are different types of treatment for patients with childhood rhabdomyosarcoma. - Children with rhabdomyosarcoma should have their treatment planned by a team of health care providers who are experts in treating cancer in children. - Some cancer treatments ca...
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<urn:uuid:00016ae0-61c9-4ca0-8b52-306236b3a6ab>
A study that included young patients with a recently recognized rare type of cardiomyopathy (a disorder of the heart muscle) linked to a genetic mutation finds that progression of this disease may be rapid and often results in early death, according to a new study. Mutations in the lysosome-associated membrane protein ...
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<urn:uuid:0001c655-3621-4f37-8fdb-e449b1400931>
Low sexual desire disorder (sexual desire/interest disorder) is lack of interest in sexual activity and sexual thoughts. A temporary reduction in sexual interest is common, often caused by temporary conditions, such as fatigue. In contrast, low sexual desire disorder causes sexual thoughts, fantasies, and desire for se...
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<urn:uuid:0001dcb3-fdf8-4afe-b798-6a3504be279b>
|Classification and external resources| Hyperaldosteronism, also aldosteronism, is a medical condition wherein too much aldosterone is produced by the adrenal glands, which can lead to lowered levels of potassium in the blood (hypokalemia). Signs and symptoms It can be asymptomatic, but these symptoms may be present: -...
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<urn:uuid:0001e2d9-98d4-423c-b365-9ed4e55bc6ab>
University of Texas Medical Branch at Galveston researchers have discovered that a drug already prescribed to millions of people with diabetes could also have another important use: treating one of the world's leading causes of blindness. In laboratory rat and cell-culture experiments, the scientists found that metform...
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<urn:uuid:000209e7-8e15-46fc-a9d0-91d8105ac934>
Human genetic diseases and normal variations can be placed into one of five categories: - single gene disorders (diseases or traits where the phenotypes are largely determined by the action, or lack of action, of mutations at individual loci); - multifactorial traits (diseases or variations where the phenotypes are str...
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<urn:uuid:00020ce3-47c6-49f5-8f24-99d3fb2808e8>
Splenic Torsion in Dogs The spleen exists as a filter to destroy excess red blood cells, and as a reservoir for blood. It is a main support to the immune system. Splenic torsion, or twisting of the spleen, may occur by itself, or in association with gastric dilatation-volvulus (GDV) syndrome, when a dog’s air-filled st...
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<urn:uuid:000213f9-7ac0-4995-be50-cf1dee8f9e92>
Oat bran can lower cholesterol, declares a new study from Syracuse University. But how well it works varies among individuals, says researcher Dr. Wendy Demark-Wahnefried. Her study of 71 men and women with high cholesterol found that a low-fat diet as well as 1.7 ounces a day of ordinary oat bran or 1.5 daily ounces o...
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<urn:uuid:00022031-4c97-4452-a7ea-d50568db8e42>
- Chai, C. and Leong, K. W., Biomaterials approach to expand and direct differentiation of stem cells, Molecular Therapy, vol. 15 no. 3 pp. 467-480 . (last updated on 2010/06/11) Stem cells play increasingly prominent roles in tissue engineering and regenerative medicine. Pluripotent embryonic stem (ES) cells theoretic...
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<urn:uuid:000227d1-927b-435f-a1df-77f9f1183ac0>
The two main types of diabetes, type 1 and type 2, are very different in their onset but very similar in their qualities of destruction. Diabetes is a serious condition, which can lead to blindness, kidney failure, heart disease, stroke and nerve damage that can cause amputation. However, thanks to breakthroughs that c...
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<urn:uuid:00025c13-2b78-48db-989a-cf515f85f0ba>
is a term for a skin reaction resulting from exposure to allergens (allergic contact dermatitis) or irritants (irritant contact dermatitis). Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight. Contact dermatitis is a localized rash or irritation of the skin caused by contact with a fore...
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<urn:uuid:00026aec-d416-4f21-85f5-89a62bbc5320>
For release: Friday, September 30, 1994 Officials at the National Institute of Neurological Disorders and Stroke (NINDS) announced that surgery can prevent stroke in carefully selected individuals who have no outward sign of disease but are at risk for stroke from a severe narrowing of a major artery in the neck. The N...
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<urn:uuid:00027801-f34b-4e58-a9ec-4b0db8634cdd>
Complications from diabetes result from constant elevations in blood glucose, which damage the blood vessels and other tissues. Excess glucose in the bloodstream results in the formation of Advanced Glycation End Products (AGEs) – products formed when sugars react with and consequently damage proteins or fats in the bo...
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<urn:uuid:00028125-8506-4727-a7d8-80fcb9e58d36>
A search for the genetic roots of towering height has led a Johns Hopkins endocrinologist to identify a mutation that causes a rare form of treatable dwarfism. Research results, published in the March issue of the Journal of Clinical Endocrinology and Metabolism, suggest that the mutation could be used as a prenatal sc...
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<urn:uuid:0002924b-c709-4aad-8366-3973b8c7d194>
A genetic variant that substantially improves survival of individuals with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, has been identified by a consortium of researchers led by John Landers, PhD, Associate Professor of Neurology and Robert Brown, MD, DPhil, Chair and Professor of Neurology ...
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<urn:uuid:00029257-a676-45f9-b21a-562f30a91d4d>
A stress fracture is an overuse injury. Bone is constantly attempting to remodel and repair itself, especially when extraordinary stress is applied. When enough stress is placed on the bone, it causes an imbalance between osteoclastic and osteblastic activity and a stress fracture may appear. Muscle fatigue can also pl...
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<urn:uuid:00029761-e4e5-4891-b5c2-4e6372e0a08f>
|Information on Pediatric GIST: A subset of GIST occurs in the pediatric age group. The incidence of pediatric GIST is smaller than in adults. Significant clinical and genetic differences are noted between adult and pediatric forms of GIST. Pediatric cases of GIST typically affect females and are located with predilect...
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<urn:uuid:000299e4-29b9-42bd-88b1-82c28dedaf19>
Magnetic Resonance Imaging Proton nuclear magnetic resonance (NMR) detects the presence of hydrogens (protons) by subjecting them to a large magnetic field to partially polarize the nuclear spins, then exciting the spins with properly tuned radio frequency (RF) radiation, and then detecting weak radio frequency radiati...
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<urn:uuid:00029c5c-f4ca-410d-a9ae-9a2647108930>
In November 1998, James Thomson, a developmental biologist at the University of Wisconsin, Madison, announced that he had isolated human embryonic stem cells. (A few days later, John D. Gearhart of the Johns Hopkins University School of Medicine made a similar claim.) The quiet, publicity-shy Thomson eventually found h...
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<urn:uuid:0002bc62-53f3-4b88-9e93-220d7d862eb0>
Box 2 shows the laboratory criteria for diagnosing mumps. Routine blood testing may show a leucopenia with a relative lymphocytosis or sometimes a neutrophil leucocytosis. Raised C reactive protein and erythrocyte sedimentation rate may also be seen.2 Box 2: Laboratory diagnostic criteria - Isolation of mumps virus or ...
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<urn:uuid:0002cbca-1d98-4f69-ab40-e1caa1194e30>
Although controversial, chemotherapy is one of the most common mainstream medical answers in the treatment of cancer. Not only is its effectiveness questionable — makers claim an extension of life as a “success” — but there is a whole slew of unpleasant and even debilitating side effects. A new analysis from researcher...
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<urn:uuid:0002ced1-da94-4b63-a685-f1acdc70bac7>
Bone densitometry is a special X-ray that measures your bone density and can be used to help predict your risk of bone fractures. This test is used to determine bone mineral content and density to diagnose osteoporosis. Osteoporosis is the loss of bone that may cause the bone to become weak. Osteoporosis commonly occur...
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<urn:uuid:0002ec55-b512-4fb7-92ea-8aa86e0f3abe>
Periodic Limb Movement Disorder (PLMD) in Adults What is periodic limb movement disorder (PLMD)? Periodic limb movement disorder (PLMD) is a condition that was formerly called sleep myoclonus or nocturnal myoclonus. It is described as repetitive limb movements that occur during sleep and cause sleep disruption. The lim...
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<urn:uuid:0002f731-21b6-4740-970e-c2a58b524de7>
Auditory maturation and congenital hearing loss in NICU infants Rijping van het auditieve systeem en congenitaal gehoorverlies bij NICU kinderen The number of preterm births has increased over the past decades as a result of increasing maternal age and in vitro fertilization (1). At the same time the survival of preter...
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<urn:uuid:00031d84-679b-4655-b794-36121c528d96>
Aphasia is an impairment of language ability. This class of language disorder ranges from having difficulty remembering words to being completely unable to speak, read, or write. Aphasia disorders usually develop quickly as a result of head injury or stroke, but can develop slowly from a brain tumor, infection, or deme...
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<urn:uuid:00035f27-bcb2-41da-95d9-15f0374f526a>
Clear cell carcinoma Clear cell carcinoma, also known as clear cell adenocarcinoma, is a very rare malignant epithelial neoplasm composed of a monomorphous population of cells that have optically clear cytoplasm with standard hematoxylin and eosin stains and lack features of other specific neoplasms. Because of inconsi...
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<urn:uuid:00037943-5654-452a-9230-443b633c5cbe>
Artificial insemination achieved widespread popularity as an infertility treatment in the 1970s. Intracervical insemination (ICI), the original technique used for artificial insemination (AI), is fairly uncomplicated in nature. The most common AI technique used today, intrauterine insemination (IUI), offers certain adv...
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<urn:uuid:00038939-9549-4765-ad6c-d5c577f40c76>
Our interventional pulmonologists use medical pleuroscopy to examine and diagnose issues in the lungs, perform biopsies of the pleural space, relieve pleural effusion (abnormal fluid buildup), and administer treatments. During this minimally invasive procedure, our doctors insert a pleuroscope (a thin tube-like scope e...
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<urn:uuid:0003a04c-8525-4433-a475-83c3457a9de1>
Diagnosis is made with reasonable certainty based on history and clinical examination. X-rays may confirm the diagnosis. Patients report good months and bad months or symptom changes with weather changes. Comparing the symptoms of arthrosis of hip on one particular day may not accurately represent the overall progressi...
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<urn:uuid:0003bd35-1913-43b8-bdc5-1e34d60d59a5>
From a presentation at the 2000 Conference of the British Lymphology Society Dr. Anthony Stanton This is most important: ask the appropriate questions and then carefully examine the limb. History of the presenting complaint. Clinical examination of the limb (always compare with the opposite limb): 1. Inspection 2. Palp...
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<urn:uuid:0003c967-9a7f-47f4-94f1-6ad5453e92f2>
A haplogroup has been defined a large cluster of people who share a common DNA heritage. It has been compared to a major branch on the human family tree. This should not be confused with a similar term called haplotype which defines a specific set of genetic mutations which describe the DNA identity of an individual or...
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<urn:uuid:0003ccdf-d9b3-4f6c-8dc1-73f012c65547>
St. Louis, October 1 -- Women who undergo routine mammograms at Missouri Baptist Medical Center now have the option of adding 3D technology to their screening. Missouri Baptist is one of the first breast centers in Missouri to offer 3D tomosynthesis for breast cancer screening.1 Breast tomosynthesis allows radiologists...
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<urn:uuid:0003d34a-0a57-47bc-a0ac-3206a475f45c>
Cerebellar Hypoplasia (CH) has been described in the context of various clinical entities: chromosomal anomalies, in utero exposure to toxins and infectious agents, metabolic disorders and a wide variety of rare genetic neurological diseases. Cerebellar maldevelopment can involve the vermis and/or the cerebellar hemisp...
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<urn:uuid:0003dfa4-04ef-46a9-81a6-867279aee9d9>
A paper examining the diverstiy of human salivary bacteria has recently appeared in the journal Genome Research (Nasidze et al. 2009). The authors looked at 120 individuals from different locations all over the world. They extracted DNA from their saliva and isolated small fragments of DNA copied from a highly variable...
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<urn:uuid:0003e08b-e398-481b-adae-13b016499788>
Sleep Disorders Center: GLOSSARY APNEA - A complete collapse of the breathing passageway during sleep. With the airway blocked, no breathing occurs and oxygen levels drop. In order to breathe again you must wake up briefly gasping for air, which leads to non‑restful sleep. AROUSAL - A shift in a person’s level of sleep...
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<urn:uuid:0003e8ab-0bf1-4619-8942-0ab2e01fd088>
Pulse oximeters measure how much of the hemoglobin in blood is carrying oxygen (oxygen saturation). If you work in healthcare (or have been patient !) you are very likely to have come across pulse oximeters. You can find them in areas such as operating rooms, recovery, critical care, wards, and ambulances. Pulse oximet...
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<urn:uuid:00040a93-7692-4dc6-bb4d-75f18ba53ae2>
The neglected tropical diseases (NTDs) are the most common conditions affecting the poorest 500 million people living in sub-Saharan Africa (SSA), and together produce a burden of disease that may be equivalent to up to one-half of SSA's malaria disease burden and more than double that caused by tuberculosis. Approxima...
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<urn:uuid:00043771-033b-47be-98c1-cb495016febf>
|WHO Recommended Surveillance Standards (WHO - OMS, 1999, 157 p.)| RATIONALE FOR SURVEILLANCE Onchocerciasis is endemic in 34 countries of Africa, the Arabian peninsula and the Americas. Success at controlling the disease in West Africa was achieved through the strategy of larviciding for vector control in order to int...
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<urn:uuid:00044115-4570-4b73-ad92-10a16c9410dc>
Conclusion of a 3-Part Series on Cellular Bioenergetics and CoQ10 Page 1 of 4 The source of life and death for neurons (nerve cells) lies in the mitochondria. These tiny organelles generate the neuron's energy and control its death. The mitochondria tend to develop defects with age. As these defects accumulate, they ca...
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<urn:uuid:00044325-fcc5-4ac7-bc5f-32cb46f91b55>
Cannabinoid receptor type 1 |Cannabinoid receptor 1 (brain)| Rendering of CNR1 from PDB |Symbols||; CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR| |External IDs||IUPHAR: ChEMBL: GeneCards:| |RNA expression pattern| The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located...
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<urn:uuid:00044372-885c-46b3-84a1-eff0676c9ec6>
Two important questions face biologists studying the infectious proteins called prions: What stops prions that infect one species from infecting another species and what causes the invisible transmission barrier between species to fail sometimes? In experiments with yeast prions reported in this week's issue of Nature,...
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<urn:uuid:00045f44-ddeb-4459-9276-e7f9cc457dce>
Prospects seem bright that the first easy-to-administer, truly new HIV drugs in years will soon emerge from the lab, giving doctors and patients hope in the increasingly difficult battle against drug-resistant HIV. Panacos Pharmaceuticals will report on an initial human study of its maturation inhibitor, the first of a...
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<urn:uuid:0004606d-4bc1-46b9-8f39-018abc8f0011>
Henry Gray (18251861). Anatomy of the Human Body. 1918. but the great majority are roundish nucleated cells, the true marrow cells of Kölliker. These marrow cells proper, or myelocytes, resemble in appearance lymphoid corpuscles, and like them are ameboid; they generally have a hyaline protoplasm, though some show gran...
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<urn:uuid:00049369-cb42-4a3f-b7ca-5e880d940739>
Cholesteatoma is a serious but treatable ear condition which can only be diagnosed by medical examination. Persisting earache, ear drainage, ear pressure, hearing loss, dizziness, or facial muscle weakness signals the need for evaluation by an otolaryngologist-head and neck surgeon. Initial treatment may consist of a c...
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<urn:uuid:0004a660-1518-4888-a68f-6ddf8222ba58>
Where DNA’s copy machine pauses, cancer could be next Each time a human cell divides, it must first make a copy of its 46 chromosomes to serve as an instruction manual for the new cell. Normally, this process goes off without a hitch. But from time to time, the information isn't copied and collated properly, leaving ga...
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<urn:uuid:0004c851-9614-4ab9-8ff2-8a6cfce27e6b>
Infants born to mothers who received the influenza vaccine while pregnant are nearly 50% less likely to be hospitalized for the flu than infants born to mothers who did not receive the vaccine while pregnant, according to a study led by researchers at Wake Forest Baptist Medical Center. The Advisory Committee on Immuni...
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<urn:uuid:0004c8e4-4595-4383-bb14-82775cd8880c>
An audiogram is a graph that shows the audible threshold for standardized frequencies as measured by an audiometer. The Y axis represents intensity measured in decibels and the X axis represents frequency measured in Hertz. The threshold of hearing is plotted relative to a standardised curve that represents 'normal' he...
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<urn:uuid:0004d7cf-0d09-4bae-a508-eaaebe50145c>
Laryngitis is an inflammation of your voice box (larynx) from overuse, irritation or infection. Inside the larynx are your vocal cords — two folds of mucous membrane covering muscle and cartilage. Normally, your vocal cords open and close smoothly, forming sounds through their movement and vibration. But in laryngitis,...
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<urn:uuid:0004e467-c2fe-4c28-ad85-354f9f10d392>
Malignant melanoma is a life threatening skin tumour which may arise on the foot. The prognosis for the condition is good when lesions are diagnosed and treated early. However, lesions arising on the soles and within the nail unit can be difficult to recognise leading to delays in diagnosis. These guidelines have been ...
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<urn:uuid:0004f448-1a13-4168-acaa-53e80b336a4e>
A growing literature supports a role for sleep after training in long-term memory consolidation and enhancement. Consequently, interrupted sleep should result in cognitive deficits. Recent evidence from an animal study indeed showed that optimal memory consolidation during sleep requires a certain amount of uninterrupt...
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<urn:uuid:00050669-0e4f-4f6c-9e25-2739cc29bea0>
NEW YORK (Reuters Health) - Having tuberculosis patients wear a surgical mask all day cuts the likelihood of them transmitting the infection through the air by nearly half, according to a new study from South Africa. "It's great to know now that it's very effective," said Dr. Rod Escombe, a researcher at Imperial Colle...
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<urn:uuid:00051944-6667-4d13-863c-dfe626c3ead6>
Date of this Version CANCER Supplement September 1, 2008, Volume 113, Number 5; DOI 10.1002/cncr.23732 BACKGROUND. Gastric cancer incidence rates for American Indians and Alaska Natives (AI/ANs) historically have exceeded those for non-Hispanic whites (NHWs). Previous reports may have underestimated the true burden of ...
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<urn:uuid:000531d4-e1ac-4566-a021-310abe894d2b>
We compared here the suitability and efficacy of traditional morphological approach and DNA barcoding to distinguish filarioid nematodes species (Nematoda, Spirurida). A reliable and rapid taxonomic identification of these parasites is the basis for a correct diagnosis of important and widespread parasitic diseases. Th...
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<urn:uuid:00053e3f-dc64-4086-9392-9f6d0743e8e5>
Medical studies of new interventions involving human subjects are called clinical trials. Such studies test new or improved therapies in volunteer participants, first determining whether they are generally safe, then whether they are effective. Although clinical trials are governed by extensive regulations to ensure th...
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<urn:uuid:000546a2-5bf3-4f38-b352-e4df0d937954>
Search research reports: Bed Bug Biology and Behavior Department of Entomology Bed bugs have a severe impact on the quality of life. This impact extends from rural communities to cities. Management of bed bug infestations is not simple, and is exacerbated by the limited availability and efficacy of insecticides. An und...
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<urn:uuid:00054f78-2e30-46b3-9cf8-2be37d79c6b7>
A recent study presents a technique allowing one to image transcription from a single gene copy in live cells, and highlights the dynamic nature of transcriptional regulation. Transcription of a gene into its messenger RNA occurs through a series of defined steps, from transcription factor binding at the promoter to pr...
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<urn:uuid:00055279-5049-48ed-87f9-eb3ef4a8754f>
Drinking Pattern and Beverage Type Modify Alcohol’s Effect on Risk of Coronary Disease To investigate the effect of drinking patterns on ischemic heart disease in 2 countries (Northern Ireland and France), researchers compared alcohol consumption, heavy episodic (“binge”) drinking,* regular drinking,† consumption frequ...
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<urn:uuid:00055f3f-bcb1-4038-91e5-8708c14d47d5>
Volume 16, Number 5—May 2010 Dengue Virus Surveillance for Early Warning, Singapore In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement...
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<urn:uuid:000571bc-3a1f-48aa-ad7b-d8dd58bc3ec2>
Vitamin D is produced in the epidermis and dermis of the skin by a small band of radiation from the sun (UV-B radiation). The primary function of vitamin D is to maintain serum calcium and phosphorus concentrations to support cellular processes, neuromuscular function, and bone ossification. Vitamin D enhances the effi...
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<urn:uuid:0005773d-c3dc-47d5-b61f-992cc7b9267d>
Myocardial infarction (Heart Attack) From Health Facts A myocardial infarction or MI occurs when the blood supply to some part of the heart muscle is abruptly stopped. MIs are caused by a number of factors. In most cases a thrombus associated with plaque rupture occludes arteries, also less frequently embolization of a...
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<urn:uuid:000598dc-7e31-47aa-95af-da15f60bfbb9>
About the nervous system in the human body In the human body, the nervous system is a complex and arguably sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: 1. The central nervous system consisting of the brain and spinal cord 2. The peripheral nervous system con...
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<urn:uuid:0005a860-e571-473b-9123-bf2fa79ad460>
Furthermore, demand is set to rise as the population's age and girth increase, both of which are risk factors for the disorder, known as obstructive sleep apnoea or OSA for short. OSA is a condition that disrupts breathing during sleep, usually as a result of the relaxation of the muscles and soft tissues in the throat...
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<urn:uuid:0005b197-554a-4dca-bf6a-be8f913c2c3d>
What are Tapeworms? Tapeworms are described as long, segmented worms that primarily live in the intestinal tract of humans and often in the bodies of animals. These parasitic worms belong to the class of Cestoda. Tapeworm infections may be caused by one of the tapeworm species and these include the pork tapeworm (Taeni...
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<urn:uuid:0005b385-36fb-4b3f-84ff-406bb7070891>
Robert C. Stanton, M.D. A normal result of cellular metabolism is the production of highly reactive forms of oxygen called oxidants. These oxidants under physiologic circumstances have important roles in many cellular activities. The normal balance of oxidants in cells is maintained by the interaction of processes that...
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<urn:uuid:0005bf6b-371f-4915-8dd5-51434df8194e>
- NHL Treatment - Hodgkin's Treatment - Clinical Trials - Monoclonal Antibodies - Types of NHL Lymphoma and Pets Monoclonal Antibody Therapy Monoclonal Antibody (mAB) Therapy is a type of immunotherapy. It employs specific antibodies to target cancer cells for removal from the body. This type of therapy relies on the b...
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<urn:uuid:0005c100-3de3-48be-8e9a-86e1de2aca59>
MicroRNAs (miRNAs) are small non-coding RNA molecules that downregulate gene expression by base pairing to the 3′-untranslated region (UTR) of target messenger RNAs (mRNAs). Up to now, rare information for the miRNAs is available in decapod crustaceans. Our previous studies showed that many miRNA-binding sites are pres...
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<urn:uuid:0005ca4c-f3d3-4c4d-9ca6-69f92ae9e80f>
Reoviridae is a family of viruses. They have a wide host range, including vertebrates, invertebrates, plants, and fungi. There are currently 87 species in this family, divided among 30 genera. Reoviruses can affect the gastrointestinal system (such as Rotavirus) and respiratory tract. The name "Reo-" is derived from re...
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<urn:uuid:0005d454-34cd-44c3-9812-21817123108b>
|Skip navigation||Hide thumbnails| Kornberg's success in unraveling the process of coenzyme synthesis established him as a biochemist by the early 1950s. It had also suggested to him that other large molecules such as the nucleic acids RNA and DNA would be synthesized in a similar way. He began his investigations into ...
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<urn:uuid:0005e677-cb27-4959-ad62-402aa19031e8>
Seniors Can Prevent Bone Loss, Fractures Bone loss and fractures in old age aren’t inevitable. Seniors can take a number of actions designed to keep their bones healthy, including eating the right foods, taking supplements and engaging in weight-bearing exercise. “Science is showing us that everything our mothers told ...
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<urn:uuid:00060684-1ad7-4683-968f-aaa432608a75>
Cell fate determination Within the field of developmental biology one goal is to understand how a particular cell (or embryo) develops into the final cell type (or organism), essentially how a cell’s fate is determined. Within an embryo, 4 processes play out at the cellular and tissue level to essentially create the fi...
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<urn:uuid:00061ae3-87c2-49fb-afa8-d33b1295e176>
Epilepsy - Topic Overview What is epilepsy? Epilepsy is a common condition that causes repeated seizures. The seizures are caused by bursts of electrical activity in the brain that are not normal. Nonepileptic Seizures (NES) - Topic Overview People with nonepileptic seizures (NES) have periods of seizure-like activity....
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<urn:uuid:00064390-77bb-4e70-9bb3-28913b07a79e>
|Home | About | Journals | Submit | Contact Us | Français| There is accumulating evidence that universally vaccinating school children would reduce the transmission of influenza. The authors sought to identify target age groups, within the pediatric population, which develop influenza the earliest and which are most st...
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<urn:uuid:00064e72-8b95-4a02-91c0-94b1e7b45fb3>
An ankle equinus deformity is basically one in which the achilles tendon is shorter than needed to allow adequate dorsiflexion during the gait cycle. If the foot is perpendicular to the leg and put through a range of motion where the foot cannot dorsiflex (move upward) more than 10 degrees this is thought of as an equi...
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<urn:uuid:00065d62-8714-4455-bdc5-0bed78c2b40e>
What is it? Echocardiography is used to look at the heart of a child or fetus. An echocardiogram is an ultrasound that helps doctors to see the structure and function of the heart and to evaluate blood flow within the heart and blood vessels. It is very informative, and one of the most common tests that we do. Why is i...
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<urn:uuid:0006741f-9db6-4029-8990-647e9ac86468>
by L. DiAnne Bradford* The basic principles underlying "personalized medicine" require a prescribing physician take into account not only empirically based guidelines, but also the individual characteristics of the person needing therapy. In deliberations about whether or not drug therapy is warranted, the selection of...
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<urn:uuid:00067a77-85e8-497c-bb20-3773b8f13005>
RF-4.1. Removal of Skeletal Atoms without affecting the Number of Rings RF-4.1.1. The removal of an unsubstituted skeletal atom, saturated or unsaturated, from a ring or an unsubstituted skeletal atom from an acyclic portion of a fundamental parent structure with its attached hydrogen atom(s) is described by the prefix...
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<urn:uuid:00068425-405f-4e3d-b79e-37d47469e902>
Hepatitis A outbreak linked to imported frozen berries Food Safety Authority of Ireland advises consumers to boil frozen fruit after 10 diagnosed with virus The FSAI said there is no evidence to suggest fresh Irish or fresh imported berries are implicated in an outbreak of Hepatitis A, which has been linked to imported...
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<urn:uuid:0006868f-03e8-40aa-ab51-41001c28d147>
Over the years, the technological focus of antibody engineering has shifted as new and better strategies were adopted throughout the antibody R&D community. Originally, mAbs were murine, constructed through a slow, laborious process of immunizing mice and fusing lymphocytes with myeloma cell lines. Thousands of such ev...
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