Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Validity of the Incremental Shuttle Walk Test to Assess Exercise Safety When Initiating Cardiac Rehabilitation in Low-Resource Settings. | PURPOSE: To evaluate the validity of the Incremental Shuttle Walk Test (ISWT) for determining risk stratification in cardiac rehabilitation (CR).METHODS: This is a cross-sectional study at a major CR center in a middle-income country. Clinically stable adult cardiac patients underwent an ISWT and an exercise test (ET),... | ['Cardiac Rehabilitation', 'Coronary Artery Disease', 'Costs and Cost Analysis', 'Cross-Sectional Studies', 'Exercise Tolerance', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Reproducibility of Results', 'Risk Factors', 'Walk Test'] | 31,022,005 | [['E02.760.169.063.500.185', 'E02.831.185', 'H02.403.680.600.250', 'N02.421.784.244'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['N03.219.151'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.680.270'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Variable laterality of corticospinal tract axons that regenerate after spinal cord injury as a result of PTEN deletion or knock-down. | Corticospinal tract (CST) axons from one hemisphere normally extend and terminate predominantly in the contralateral spinal cord. We previously showed that deleting the gene phosphatase and tensin homolog (PTEN) in the sensorimotor cortex enables CST axons to regenerate after spinal cord injury and that some regenerati... | ['Animals', 'Axons', 'Female', 'Functional Laterality', 'Gene Knockdown Techniques', 'Male', 'Mice', 'Mice, Knockout', 'Nerve Regeneration', 'PTEN Phosphohydrolase', 'Pyramidal Tracts', 'Spinal Cord Injuries'] | 26,878,190 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['F02.830.297.425', 'G11.561.225.425'], ['E05.393.335.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.50... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toxigenic V. cholerae, V. parahaemolyticus | Oysters can accumulate potentially pathogenic bacteria, such as Vibrio cholerae, V. parahaemolyticus, and V. vulnificus. The aim of this study was to detect the presence of these Vibrio species and their toxigenic variants in oysters from the Gulf of Mexico sold in Mexico City. Oyster samples were studied using traditi... | ['Animals', 'Bacterial Toxins', 'Colony Count, Microbial', 'Food Microbiology', 'Genotype', 'Gulf of Mexico', 'Mexico', 'Ostreidae', 'Polymerase Chain Reaction', 'Seafood', 'Seasons', 'Vibrio'] | 30,479,158 | [['B01.050'], ['D23.946.123'], ['E01.370.225.875.220', 'E05.200.875.220'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['G05.380'], ['Z01.756.092.325'], ['Z01.107.567.589'], ['B01.050.500.644.080.643'], ['E05.393.620.500'], ['G07.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Isolation and characterization of islet stellate cells in rat. | The central role of PSCs in pancreatic fibrogenesis is well established. However, the mechanism responsible for the islet fibrosis presenting in the late stage of T2DM has not been fully elucidated. This study was designed to determine whether the endocrine pancreatic islets contain cells resembling PSCs. PSCs were iso... | ['Actins', 'Animals', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Collagen Type I', 'Collagen Type III', 'Diabetes Mellitus, Type 2', 'Fibronectins', 'Fibrosis', 'Glial Fibrillary Acidic Protein', 'Islets of Langerhans', 'Lipid Metabolism', 'Pancreas', 'Pancreatic Stellate Cells', 'Rats', 'Rats, Wistar',... | 25,483,957 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['C18.452.394.750.149', 'C19.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Observations on quality senior health business: success patterns and policy implications. | OBJECTIVE: Population ageing is a global issue that affects almost every country. Most ageing researches focused on demand side and studies related to supply side were relatively scarce. This study selected quality enterprises focus on ageing health and analysed their patterns on providing quality services successfully... | ['Aged', 'Cross-Sectional Studies', 'Health Facility Administrators', 'Health Services for the Aged', 'Humans', 'Interviews as Topic', 'Organizational Policy', 'Quality of Health Care', 'Taiwan'] | 26,968,683 | [['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.526.070.490', 'M01.526.485.430', 'N02.360.430'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['I01.655.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Comparison of different methods of ventilation via cannula cricothyroidotomy in a trachea-lung model. | BACKGROUND: Cannula cricothyroidotomy is recommended in recent guidelines as a rescue intervention in the 'cannot-intubate cannot-ventilate' scenario. Several methods of providing ventilation via a cannula cricothyroidotomy have been described, but there are no data comparing these methods and using cannulae of differi... | ['Airway Obstruction', 'Cricoid Cartilage', 'Humans', 'Models, Anatomic', 'Respiration, Artificial', 'Thyroid Cartilage', 'Tracheostomy'] | 19,797,248 | [['C08.618.846.185'], ['A02.165.257.625.211', 'A02.165.407.500.211', 'A04.329.591.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['A02.165.257.625.870', 'A02.165.407.500.870', 'A04.329.591.870'], ['E02.04... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Management in general practice of patients with persistent dyspepsia. A decision analysis. | To determine whether an empirical drug treatment strategy (empirical group) instead of upper gastrointestinal endoscopy followed by treatment (conventional group) in patients with persistent dyspepsia increases appropriate use of endoscopy facilities, we did a decision analysis based on data found in the literature. We... | ['Decision Trees', 'Disease Management', 'Dyspepsia', 'Endoscopy', 'Gastroenterology', 'Humans', 'Omeprazole', 'Treatment Outcome'] | 9,451,663 | [['G17.162.500'], ['N04.590.607'], ['C23.888.821.236'], ['E01.370.388.250', 'E04.502.250'], ['H02.403.429.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.640.074.500', 'D03.383.725.024.500', 'D03.633.100.103.034.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A stress "deafness" effect in European Portuguese. | Research on the perception of word stress suggests that speakers of languages with non-predictable or variable stress (e.g., English and Spanish) are more efficient than speakers of languages with fixed stress (e.g., French and Finnish) at distinguishing nonsense words contrasting in stress location. In addition, segme... | ['Cues', 'Discrimination, Psychological', 'Female', 'Humans', 'Male', 'Phonetics', 'Pitch Discrimination', 'Sound Spectrography', 'Speech Acoustics', 'Speech Perception', 'Speech Production Measurement', 'Time Factors', 'Voice Quality'] | 25,935,937 | [['F02.463.425.234'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.518'], ['F02.463.593.071.700.408', 'G07.888.125.700.408'], ['E05.855'], ['G11.561.812.650', 'G11.561.820'], ['F02.463.593.071.875', 'G07.888.125.875'], ['E01.370.760'], ['G01.910.857'], ['G09.772.925.960']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Electron microscopic study of the kinetics of smallpox vaccine interaction with alveolar macrophages when administered intratracheally]. | Electron microscopy was applied to the study of the dynamics of endocytosis of smallpox vaccine by alveolar macrophages in intratracheal immunization of guinea pigs; 5 to 15 minutes after administration of smallpox vaccine the viruses were absorbed on the macrophage surface, penetrated into the cells by invagination an... | ['Administration, Oral', 'Aerosols', 'Animals', 'Guinea Pigs', 'Immunization', 'Kinetics', 'Macrophages', 'Microscopy, Electron', 'Pulmonary Alveoli', 'Rabbits', 'Smallpox Vaccine', 'Time Factors'] | 948,955 | [['E02.319.267.100'], ['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['B01.050.150.900.649.313.992.550'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['G01.374.661', 'G02.111.490'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFêB pathway. | Paclitaxel (Taxol) is currently used as the front-line chemotherapeutic agent for several cancers including ovarian carcinoma; however, the drug frequently induces drug resistance through multiple mechanisms. The new strategy of using natural compounds in combination therapies is highly attractive because those compoun... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Line, Tumor', 'Down-Regulation', 'Drug Resistance, Neoplasm', 'Drug Synergism', 'Female', 'Humans', 'Isoflavones', 'NF-kappa B', 'Ovarian Neoplasms', 'Paclitaxel', 'Phosphatidylinositol 3-Kinases', 'Proto-Oncogene Proteins c-akt', 'Receptors, Estrogen', 'Signal T... | 23,027,625 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G07.690.773.984.395'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['D05.500.672', 'D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urethral prolapse in a premenarchal Asian girl. | BACKGROUND: Urethral prolapse is an uncommon condition characterized by complete circular eversion of the urethral mucosa through the external meatus.CASE: We present the case of a 9-year-old Asian girl who presented with 3 days of vaginal spotting and a painless vulvar mass. After several unsuccessful attempts of manu... | ['Child', 'Female', 'Humans', 'Prolapse', 'Urethral Diseases', 'Urologic Surgical Procedures', 'Vaginal Diseases'] | 19,155,936 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.842'], ['C12.777.767', 'C13.351.968.767'], ['E04.950.774'], ['C13.351.500.894']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Functional genetic polymorphisms in cytokines and metabolic genes as additional genetic markers for susceptibility to develop type 1 diabetes. | Genetic association with type 1 diabetes (T1D) has been established for two chromosomal regions: HLA DQ/DR (IDDM1) and INS VNTR (IDDM2). To identify additional genetic markers, we tested polymorphisms in regulatory regions of several cytokine and important metabolic genes. These polymorphisms exhibit functional consequ... | ['Adolescent', 'Child', 'Child, Preschool', 'Cytokines', 'Diabetes Mellitus, Type 1', 'Female', 'Gene Frequency', 'Genetic Markers', 'Genetic Predisposition to Disease', 'Genetic Testing', 'HLA-DR Antigens', 'Humans', 'Male', 'Metabolism', 'Polymorphism, Genetic'] | 14,735,147 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G05.330'], ['D23.101.387', 'G05.695.450'], ['C23.550.291.687.500', 'G05.380.355'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In situ monitoring of the DNA hybridization by attenuated total reflection surface-enhanced infrared absorption spectroscopy. | In situ monitoring of DNA hybridization kinetics is achieved via an attenuated total reflection surface-enhanced infrared absorption spectroscopy (ATR-SEIRAS) technique using a sandwich assay structure. The synergistic enhancement effect gives this ATR-SEIRAS-based detection strategy promise to be a convenient and uniq... | ['DNA', 'In Situ Hybridization', 'Kinetics', 'Methods', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties'] | 22,246,240 | [['D13.444.308'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['G01.374.661', 'G02.111.490'], ['E05.581'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ectopic expression of RET results in microphthalmia and tumors in the retinal pigment epithelium. | The retinal pigment epithelium (RPE) is essential for eye development by interacting with the overlaying neuroepithelium. Regulatory sequences of the gene encoding for tyrosinase-related protein 1 (TRP-1), linked to the lacZ reporter gene, lead to strong and specific beta-galactosidase expression in the RPE. We asked h... | ['Animals', 'Drosophila Proteins', 'Eye Neoplasms', 'Female', 'Gene Expression', 'Lac Operon', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microphthalmos', 'Oxidoreductases', 'Pigment Epithelium of Eye', 'Proteins', 'Proto-Oncogene Proteins', 'Proto-Oncoge... | 9,935,163 | [['B01.050'], ['D12.776.093.500.462'], ['C04.588.364', 'C11.319'], ['G05.297'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lead (Pb) exposure promotes diabetes in obese rodents. | BACKGROUND: Pb (lead) exposure occurs at elevated frequency in urban inner city populations that also have high rates of obesity and diabetes.OBJECTIVES: To determine if Pb can promote the development of diabetes in a setting of obesity, we examined the effect of Pb exposure on glucose metabolism in a rodent model of o... | ['Animals', 'Cells, Cultured', 'Diabetes Mellitus, Experimental', 'Female', 'Glucose Intolerance', 'Hyperglycemia', 'Lead', 'Obesity', 'Rats', 'Rats, Zucker'] | 27,908,418 | [['B01.050'], ['A11.251'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.952.500'], ['C18.452.394.952'], ['D01.268.556.435', 'D01.552.544.435'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis. | BACKGROUND: Previous studies have examined the association between polymorphisms in the coagulation factor VII gene and the risk of coronary heart disease (CHD), but those studies have been inconclusive. This study was conducted to assess the associations between these polymorphisms and CHD and evaluated the associatio... | ['Asian Continental Ancestry Group', 'Case-Control Studies', 'Coronary Disease', 'European Continental Ancestry Group', 'Factor VII', 'Humans', 'Odds Ratio', 'Polymorphism, Genetic', 'Risk Factors'] | 21,838,885 | [['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C14.280.647.250', 'C14.907.585.250'], ['M01.686.508.400'], ['D08.622.432', 'D12.776.124.125.325', 'D12.776.811.243.432', 'D23.119.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.600', 'G17.68... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insulin-like growth factor I stimulates human erythroid colony formation in vitro. | The effects of human GH and insulin-like growth factor I on the proliferation and differentiation of erythroid progenitor cells from the bone marrow and peripheral blood of children were studied in a hormone-depleted culture system. Growth of erythroid progenitors was quantified by directly scoring colonies and by bioc... | ['Bone Marrow Cells', 'Cell Differentiation', 'Child', 'Child, Preschool', 'Colony-Forming Units Assay', 'Erythrocytes', 'Erythropoiesis', 'Growth Hormone', 'Humans', 'Hydroxymethylbilane Synthase', 'In Vitro Techniques', 'Insulin-Like Growth Factor I', 'Somatomedins'] | 3,584,401 | [['A11.148', 'A15.378.316'], ['G04.152'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G04.152.825.414', 'G09.188.343.414'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Non-universal tracer diffusion in crowded media of non-inert obstacles. | We study the diffusion of a tracer particle, which moves in continuum space between a lattice of excluded volume, immobile non-inert obstacles. In particular, we analyse how the strength of the tracer-obstacle interactions and the volume occupancy of the crowders alter the diffusive motion of the tracer. From the detai... | ['Computer Simulation', 'Diffusion', 'Indicators and Reagents', 'Models, Biological'] | 25,474,476 | [['L01.224.160'], ['G01.202', 'G02.196'], ['D27.720.470.410'], ['E05.599.395']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Personal training simulator for asynchronous learning of obstetric ultrasound. | To meet the challenges of providing affordable, efficient ultrasound training, a low-cost, portable personal ultrasound training simulator with structured curriculums and integrated assessment methods has been developed. By using extended image volumes for training, the realistic experience of scanning over a larger bo... | ['Computer-Assisted Instruction', 'Female', 'High Fidelity Simulation Training', 'Humans', 'Image Interpretation, Computer-Assisted', 'Manikins', 'Obstetrics', 'Phantoms, Imaging', 'Ultrasonography, Prenatal', 'User-Computer Interface'] | 24,732,517 | [['I02.903.771.500.208'], ['I02.903.847.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['J01.897.280.500.545.129.400', 'L01.178.820.090.545.129.400'], ['H02.403.810.450'], ['E07.671'], ['E01.370.350.850.865', 'E01.370.378.630.865'], ['L01.224.9... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis. | Our objective was to assess the copper(II) complex of diacetylbis(4-methylthiosemicarbazone) [Cu(II)(atsm)] for its preclinical potential as a novel therapeutic for ALS. Experimental paradigms used were designed to assess Cu(II)(atsm) efficacy relative to treatment with riluzole, as a function of dose administered, and... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Copper', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Transgenic', 'Organometallic Compounds', 'Random Allocation', 'Superoxide Dismutase', 'Thiosemicarbazones', 'Treatment Outcome'] | 23,952,668 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fast and simple method for semiquantitative determination of calcium propionate in bread samples. | Calcium propionate has been widely used as a preservative in bakery and in bread. It is sometimes not carefully used, or a high concentration is added to preserve products. High consumption of calcium propionate can lead to several health problems. This study aims to develop a fast and simple semiquantitative method ba... | ['Bread', 'Chromatography, High Pressure Liquid', 'Propionates', 'Thailand'] | 28,911,666 | [['G07.203.300.100', 'J02.500.100'], ['E05.196.181.400.300'], ['D02.241.081.751', 'D10.251.400.706'], ['Z01.252.145.841']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
The role of assessment in the student learning process. | Assessment is a powerful learning tool that can enhance learning and education. The process of student assessment should align with curricular goals and educational objectives. Identifying the assessment strategies necessary for the proper evaluation of students' progress within individual programs is as important as e... | ['Canada', 'Clinical Competence', 'Curriculum', 'Education, Veterinary', 'Educational Measurement', 'Humans', 'Program Development', 'Role', 'Students, Medical'] | 22,023,924 | [['Z01.107.567.176'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.588'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.760'], ['F01.829.316.616'], ['M01.848.769.602']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Paracetamol vs piroxicam to relieve pain in renal colic. Results of a randomized controlled trial. | PURPOSE: We tested whether paracetamol could improve pain relief in patients visiting the emergency department with acute renal colic as compared to piroxicam, a nonsteroidal anti-inflammatory drug (NSAID).MATERIALS AND METHODS: Patients with a diagnosis of acute renal colic were prospectively randomized to receive eit... | ['Acetaminophen', 'Adult', 'Analgesics, Non-Narcotic', 'Anti-Inflammatory Agents, Non-Steroidal', 'Female', 'Humans', 'Male', 'Pain', 'Pain Measurement', 'Piroxicam', 'Prospective Studies', 'Renal Colic', 'Tunisia'] | 20,934,829 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.116'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'],... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Roux-en-Y jejunal loop and bile reflux. | BACKGROUND: The current opinion is that the reflux of jejunal juice over the whole length of a long Roux-en-Y jejunal loop is very uncommon. We aimed to challenge this concept by monitoring the presence of bile in the organ proximal to a 60-cm loop during a 24-hour period with use of the Bilitec device, an optoelectron... | ['Adult', 'Aged', 'Anastomosis, Roux-en-Y', 'Bile Reflux', 'Cholecystectomy', 'Duodenum', 'Female', 'Fiber Optic Technology', 'Follow-Up Studies', 'Gastrectomy', 'Humans', 'Jejunum', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Postoperative Complications', 'Vagotomy, Truncal'] | 10,875,990 | [['M01.060.116'], ['M01.060.116.100'], ['E04.035.070', 'E04.210.070'], ['C06.130.140', 'C06.405.748.240.140'], ['E04.210.120.172'], ['A03.556.124.684.124', 'A03.556.875.249'], ['H01.671.617.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.419'], ['B01.050.150.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of 670-nm low laser therapy on herpes simplex type 1. | OBJECTIVE: The purpose of this work was to study the effect of low-level laser therapy (LLLT) on the healing and relapse intervals in patients with recurrent labial herpes simplex infections.BACKGROUND DATA: Several pharmaceuticals are available to reduce symptoms and improb? healing of labial herpes, but only LLLT has... | ['Adolescent', 'Adult', 'Antiviral Agents', 'Female', 'Herpes Labialis', 'Herpesvirus 1, Human', 'Humans', 'Lasers, Semiconductor', 'Low-Level Light Therapy', 'Male', 'Middle Aged', 'Recurrence', 'Young Adult'] | 22,047,597 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388'], ['C01.925.256.466.382.316', 'C01.925.825.320.320', 'C07.465.409.466', 'C17.800.838.790.320.320'], ['B04.280.382.100.750.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.480', 'E07.710.520.480'], ['E02.594.540', 'E02.774.500'], ['M01.060.11... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-chain polyunsaturated fatty acids promote paclitaxel cytotoxicity via inhibition of the MDR1 gene in the human colon cancer Caco-2 cell line. | OBJECTIVE: Accumulating evidence in both humans and animal models indicates that dietary intake of long-chain polyunsaturated fatty acids (PUFAs) can improve response to chemotherapy. The intent of this study was to determine the mechanisms by which PUFAs affect the response to anticancer chemotherapy.METHODS: Human co... | ['ATP Binding Cassette Transporter, Subfamily B', 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antineoplastic Agents', 'Apoptosis', 'Blotting, Western', 'Caco-2 Cells', 'Docosahexaenoic Acids', 'Drug Resistance, Multiple', 'Eicosapentaenoic Acid', 'Fatty Acids, Omega-6', 'Fatty Acids, Unsaturated', 'Fish... | 21,917,707 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aphagia, behavior sequencing and body weight set point following orbital frontal lesions in rats. | Discrete lesions were made in the orbital frontal neocortex of rats and eating, drinking, sensorimotor responsiveness, and sequencing of motor acts were studied. Duration of aphagia was related to palatability/texture of food. Rats were aphagic for a mean of two days to palatable cookie mash presented on a spatula, six... | ['Animals', 'Body Weight', 'Brain Mapping', 'Brain Stem', 'Drinking', 'Eating', 'Energy Metabolism', 'Frontal Lobe', 'Grooming', 'Hypothalamus', 'Male', 'Neural Pathways', 'Prefrontal Cortex', 'Psychomotor Performance', 'Rats', 'Rats, Long-Evans', 'Serial Learning', 'Taste'] | 11,803,698 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132'], ['G07.203.650.283.249', 'G10.261.330.249'], ['G07.203.650.283', 'G10.261.330'], ['G03.295'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protection of tree shrews by pVAX-PS DNA vaccine against HBV infection. | The immunological protection of pVAX-PS, a DNA vaccine, was assessed in the tree shrews model. pVAX-PS was constructed by inserting the gene encoding the middle (pre-S2 plus S) envelope protein of HBV into a plasmid vector pVAX1. Tree shrews (Tupaia belangeri chinenesis) were experimentally infected with human HBV by i... | ['Animals', 'Disease Models, Animal', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Vaccines', 'Humans', 'Liver', 'Time Factors', 'Tupaiidae', 'Vaccines, DNA'] | 12,932,306 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.548.114.254.450.504'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinicopathological characteristics of interstitial foam cells in membranous nephropathy. | BACKGROUND: Interstitial foam cells are occasionally observed in various renal diseases, and they have been reported to belong to the monocyte/macrophage (M phi) lineage and to be associated with heavy proteinuria and hyperlipidemia. We investigated the characteristics of interstitial foam cells and their association w... | ['Adult', 'Aged', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Female', 'Foam Cells', 'Glomerulonephritis, Membranous', 'Humans', 'Immunohistochemistry', 'Intercellular Adhesion Molecule-1', 'Kidney', 'Lymphocyte Function-Associated Antigen-1', 'Male', 'Middle Aged'] | 10,412,760 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['A11.329.372.368', 'A11.627.482.368', 'A11.733.397.368', 'A15.382.670.522.368', 'A15.382.680.397.368'], ['C12.777.419.570.363.625', 'C13.351.968.419.570.363.625', 'C20.111.535'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis. | Small GTPase Ras homologue enriched in brain (RHEB) binds and activates the key metabolic regulator mTORC1, which has an important role in cancer cells, but the role of RHEB in cancer pathogenesis has not been shown. By performing a meta-analysis of published cancer cytogenetic and transcriptome databases, we defined a... | ['Animals', 'Cell Line, Tumor', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Keratinocytes', 'Mechanistic Target of Rapamycin Complex 1', 'Mice', 'Mice, Transgenic', 'Monomeric GTP-Binding Proteins', 'Multiprotein Complexes', 'Neurope... | 20,388,784 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['A11.409.500', 'A11.436.397'], ['D05.500.337', 'D08.811.913.696.620.682.700.931.500', 'D12.776.476.925.500'], ['B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gonorrhea in the United States 1975-1984: is the giant only sleeping? | After a decade of increase, the number of cases of gonorrhea declined by 12% in the United States between 1975 and 1984. During the same period gonorrhea rates declined by 20%. We examined age-, sex-, and race-specific gonorrhea cases and rates to determine whether the national trend has been occurring in all populatio... | ['Adolescent', 'Adult', 'African Americans', 'Age Factors', 'Child', 'European Continental Ancestry Group', 'Female', 'Gonorrhea', 'Humans', 'Male', 'Sex Factors', 'United States'] | 3,616,855 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.686.508.400'], ['C01.150.252.400.625.275', 'C01.150.252.734.401', 'C01.221.812.281.401', 'C01.778.281.401', 'C12.294.668.281.401', 'C13.351.500.711.281.401'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Infection of chimpanzee peripheral blood mononuclear cells by human immunodeficiency virus type 1 requires cooperative interaction between multiple variable regions of gp120. | We have recently reported the isolation and molecular cloning of a human immunodeficiency virus type 1 isolate (HIV-1 DH125) that exhibits rapid replication kinetics and marked cytopathicity in both human and chimpanzee peripheral blood mononuclear cells (PBMC). To identify the viral determinants responsible for infect... | ['Animals', 'HIV Envelope Protein gp120', 'HIV Infections', 'HIV-1', 'Humans', 'Leukocytes, Mononuclear', 'Pan troglodytes', 'Reassortant Viruses'] | 8,794,390 | [['B01.050'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.164.249', 'D23.050.327.520.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
o-Diphenol oxidase activity of molluscan hemocyanins. | Diphenoloxidase activities of two molluscan hemocyanins, isolated from the marine snails Rapana venosa and garden snails Helix vulgaris were studied using o-diphenol and L-Dopa as substrates. The dimers of H. vulgaris Hc show both, diphenol (K(m)=2.86 mM and K(cat)=4.48) and L-Dopa activity due to a more open active si... | ['Amino Acid Sequence', 'Animals', 'Catalysis', 'Catechol Oxidase', 'Hemocyanins', 'Kinetics', 'Molecular Sequence Data', 'Mollusca', 'Oxidation-Reduction', 'Protein Subunits'] | 18,162,195 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.130'], ['D08.811.682.690.708.125'], ['D12.776.093.375', 'D12.776.556.462', 'D23.767.482'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['B01.050.500.644'], ['G02.700', 'G03.295.531'], ['D12.776.813']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation. | Phosphorylation of the MAPK isoform ERK by G protein-coupled receptors involves multiple signaling pathways. One of these pathways entails growth factor receptor transactivation followed by ERK activation. This study demonstrates that a similar signaling pathway is used by the mu-opioid receptor (MOR) expressed in HEK2... | ['Animals', 'Calmodulin', 'Cell Line', 'Colforsin', 'Cross-Linking Reagents', 'Dose-Response Relationship, Drug', 'Enzyme Activation', 'ErbB Receptors', 'Humans', 'MAP Kinase Signaling System', 'Mitogen-Activated Protein Kinases', 'Models, Biological', 'Mutation', 'Phenanthrolines', 'Phosphorylation', 'Precipitin Tests... | 11,457,825 | [['B01.050'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['A11.251.210'], ['D02.455.849.291.300'], ['D27.720.470.410.210'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.263', 'G03.328'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer. | The majority of tumors from patients affected by hereditary nonpolyposis colorectal cancer (HNPCC) exhibit a mutator phenotype characterized by widespread microsatellite instability (MSI) and somatic mutations in repeated sequences in several cancer-associated genes. An inverse relationship between MSI and chromosomal ... | ['Adaptor Proteins, Signal Transducing', 'Carrier Proteins', 'Chromosome Aberrations', 'Colonic Neoplasms', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'DNA Mutational Analysis', 'DNA, Neoplasm', 'Female', 'Flow Cytometry', 'Genetic Heterogeneity', 'Genetic Predisposition to Disease', 'Humans', 'In Situ Hybridizat... | 11,996,796 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.157'], ['C23.550.210', 'G05.365.590.175'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.30... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Comparative efficiency of a course of multi-factor physiotherapeutic treatment and a complex of instrumental physiotherapy technics for medical rehabilitation of patients with stable angina pectoris]. | Examination of comparable groups of patients with angina of efforts has demonstrated identical clinical efficiency of multi-factor therapeutic modalities and methods of instrumental physiotherapy for medical rehabilitation of patients with stable angina of effort. The results of this study suggest the possibility to av... | ['Angina Pectoris', 'Autonomic Nervous System', 'Hemostasis', 'Humans', 'Lipid Metabolism', 'Physical Therapy Modalities', 'Treatment Outcome'] | 19,882,888 | [['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['A08.800.050'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['E02.779', 'E02.831.535'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Developmental toxicity, uptake and distribution of sodium chromate assayed by frog embryo teratogenesis assay-Xenopus(FETAX). | The embryotoxicity and teratogenicity of Cr(VI) on the survival and morphology of the anuran Xenopus laevis have been assessed by frog embryo teratogenesis assay-Xenopus (FETAX). The lethal median (LC(50)) and teratogenic median (TC(50)) concentration values of Cr(VI) were 890 microM and 260 microM, respectively. The c... | ['Animals', 'Chromates', 'Chromatography, Gel', 'DNA Adducts', 'Female', 'Larva', 'Sodium Compounds', 'Teratogens', 'Xenopus laevis'] | 19,540,565 | [['B01.050'], ['D01.220.150', 'D01.248.497.158.235'], ['E05.196.181.400.250'], ['D13.444.308.135', 'G05.200.104'], ['B05.500.500', 'G07.345.500.550.500.500'], ['D01.857'], ['D27.888.569.864'], ['B01.050.150.900.090.180.610.500.562']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. | We presently describe the full-length cloning and functional characterization of an HIV-1-inducible gene, astrocyte elevated gene (AEG)-1. Additionally, a novel method is outlined for producing tag-free recombinant protein in a baculovirus system and its use in producing AEG-1 protein. AEG-1 mRNA is expressed ubiquitou... | ['Amino Acid Transport System X-AG', 'Antibodies', 'Astrocytes', 'Blotting, Northern', 'Blotting, Western', 'Brain', 'Cell Adhesion', 'Cell Adhesion Molecules', 'Cell Line', 'Cell Line, Tumor', 'Cell Proliferation', 'Cells, Cultured', 'Cloning, Molecular', 'DNA, Complementary', 'Excitatory Amino Acid Transporter 2', 'F... | 15,927,426 | [['D12.776.157.530.200.249.500', 'D12.776.157.530.937.250', 'D12.776.543.585.200.249.500', 'D12.776.543.585.937.250'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A08.637.200', 'A11.650.200'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.30... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biomechanical comparison of wire osteosynthesis techniques in craniofacial surgery. | The biomechanical stability of 20 different craniofacial wire osteosynthesis methods were tested in a simulated bone model. Utilizing wire fixation across a curved osteotomy site of an acrylic bar fixed at one end, compressive loading at the suspended end was used to test the resistance of the ligatures to stretch fail... | ['Analysis of Variance', 'Bone Plates', 'Bone Wires', 'Child', 'Humans', 'Materials Testing', 'Models, Structural', 'Osteotomy', 'Skull', 'Stainless Steel', 'Tensile Strength'] | 8,031,977 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['J01.897.280.500.545',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Irreducible distal radioulnar joint occurring in a Galeazzi fracture - case report. | This is a report of an irreducible distal radioulnar joint associated with a Galeazzi fracture. The irreducible dislocation of the radioulnar joint was not appreciated until 2 weeks following compression plating of the radius fracture. The extensor carpi ulnaris was found to be wrapped anteriorly about the ulnar border... | ['Adult', 'Bone Plates', 'Fracture Fixation, Internal', 'Humans', 'Joint Dislocations', 'Male', 'Orthopedic Fixation Devices', 'Postoperative Complications', 'Radiography', 'Radius Fractures', 'Ulna', 'Ulna Fractures'] | 7,240,681 | [['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['E07.858.442.660', 'E07.858.690.725'], ['C23.550.767'], ['E01.370.350.700'], ['C26.088.268.556', 'C26.404.562'], ['A02.835.232.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sexual disorders in Huntington's disease. | This study assessed the frequency and type of sexual disorders associated with Huntington's disease (HD) in an unbiased sample. Of 39 HD patients and 32 of their partners, 82% and 66%, respectively, had one or more sexual disorders by DSM-III-R criteria. The most frequent for both groups was hypoactive sexual disorder.... | ['Adult', 'Aged', 'Female', 'Humans', 'Huntington Disease', 'Libido', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Paraphilic Disorders', 'Personality Assessment', 'Sexual Dysfunctions, Psychological'] | 8,044,036 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.545', 'C10.228.140.380.278', 'C10.228.662.262.249.750', 'C10.574.500.497', 'C16.320.400.430', 'F03.615.250.400', 'F03.615.400.390'], ['F02.739.794.511'], ['M01.060.116.630'], ['F04.711.513'], ['F03.657'], ['F04.513... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of multiple antigen substrates to detect antinuclear antibody in canine sera. | The presence of antinuclear antibody in serum has been used to serologically support the clinical diagnosis of systemic lupus erythematosus. Most often, diagnostic support is conferred if the titer is above a "cut-off" value determined by the particular laboratory. The precision estimates of these commonly used serolog... | ['Animals', 'Antibodies, Antinuclear', 'Dog Diseases', 'Dogs', 'Fluorescent Antibody Technique', 'Hemagglutination Tests', 'Lupus Erythematosus, Systemic', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 2,053,272 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Computer-based design of novel HIV-1 entry inhibitors: neomycin conjugated to arginine peptides at two specific sites. | Aminoglycoside-arginine conjugates (AAC and APAC) are multi-target inhibitors of human immunodeficiency virus type-1 (HIV-1). Here, we predict new conjugates of neomycin with two arginine peptide chains binding at specific sites on neomycin [poly-arginine-neomycin-poly-arginine (PA-Neo-PA)]. The rationale for the desig... | ['Aminoglycosides', 'Anti-HIV Agents', 'Arginine', 'Computer Simulation', 'Drug Design', 'HIV Envelope Protein gp120', 'HIV-1', 'Humans', 'Ligands', 'Models, Molecular', 'Neomycin', 'Oligopeptides', 'Peptides', 'Protein Synthesis Inhibitors', 'Receptors, CXCR4', 'Static Electricity'] | 19,057,930 | [['D09.408.051'], ['D27.505.954.122.388.077.088'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['L01.224.160'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.164.249', 'D23.050.327.520.350'], ['B0... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Sialendoscopy enhances salivary gland function in Sj?gren's syndrome: a 6-month follow-up, randomised and controlled, single blind study. | OBJECTIVES: To assess the effect of sialendoscopy of the major salivary glands on salivary flow and xerostomia in patients with Sj?gren's syndrome (SS).METHODS: Forty-nine patients with SS were randomly assigned to a control group (n=15) and two intervention groups: irrigation of the major glands with saline (n=16) or ... | ['Adult', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Recovery of Function', 'Reference Values', 'Saline Solution', 'Saliva', 'Salivary Glands', 'Salivation', 'Severity of Illness Index', 'Single-Blind Method', "Sjogren's Syndrome", 'Therapeutic Irrigation', 'Treatment Outcome', 'Triamcinolone', 'Xerostomi... | 29,475,854 | [['M01.060.116'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G16.757'], ['E05.978.810'], ['D26.776.498.500.750'], ['A12.200.666'], ['A03.556.500.760', 'A10.336.779', 'A14.549.760'], ['G07.203.650.250.800', 'G10.261.190.800'], ['E05.318.308.980.438.475.456... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. | Three structures have been determined for complexes between HhaI methyltransferase (M.HhaI) and oligonucleotides containing a G:A, G:U or G:AP (AP = abasic or apurinic/apyrimidinic) mismatch at the target base pair. The mismatched adenine, uracil and abasic site are all flipped out of the DNA helix and located in the e... | ['Base Pair Mismatch', 'Crystallography, X-Ray', 'DNA-Cytosine Methylases', 'Models, Molecular', 'Nucleic Acid Conformation', 'Oligodeoxyribonucleotides', 'Protein Conformation', 'S-Adenosylhomocysteine'] | 9,783,745 | [['G05.365.590.060'], ['E05.196.309.742.225'], ['D08.811.913.555.500.350.100'], ['E05.599.595'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424.450'], ['G02.111.570.820.709'], ['D02.886.030.498.050', 'D03.633.100.759.590.138.240', 'D12.125.166.498.050', 'D13.570.583.138.240', 'D13.570.800.096.262']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Integrating spatial fuzzy clustering with level set methods for automated medical image segmentation. | The performance of the level set segmentation is subject to appropriate initialization and optimal configuration of controlling parameters, which require substantial manual intervention. A new fuzzy level set algorithm is proposed in this paper to facilitate medical image segmentation. It is able to directly evolve fro... | ['Algorithms', 'Brain', 'Carotid Arteries', 'Cluster Analysis', 'Diagnostic Imaging', 'Fuzzy Logic', 'Humans', 'Image Processing, Computer-Assisted', 'Liver', 'Radiography', 'Ultrasonography'] | 21,074,756 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['A07.015.114.186'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E01.370.350'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A03.620'], ['E01.370.350.700'], ['E01.370.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Clinical and epidemiologic features of group a streptococcal pneumonia in Ontario, Canada. | BACKGROUND: Since the 1960s, group A streptococcus (GAS) has accounted for less than 1% of cases of community-acquired pneumonia. During the past 2 decades there has been a resurgence of invasive GAS infection, but no large study of GAS pneumonia has been performed.METHODS: To determine the clinical and epidemiologic f... | ['Chi-Square Distribution', 'Cross Infection', 'Disease Outbreaks', 'Fasciitis, Necrotizing', 'Hospital Mortality', 'Humans', 'Incidence', 'Ontario', 'Pneumonia', 'Population Surveillance', 'Risk Factors', 'Shock, Septic', 'Streptococcal Infections', 'Streptococcus pyogenes'] | 12,588,207 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C01.248', 'C23.550.291.875.500'], ['N06.850.290'], ['C05.321.550'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Acetabular revision with the Burch-Schnieder antiprotrusio cage and cancellous allograft bone. | A retrospective review of 25 patients who underwent 28 acetabular revisions with the Burch-Schnieder antiprotrusio cage (Protek, Berne, Switzerland) and cancellous allograft bone was performed. Follow-up periods averaged 33 months. Patients had averaged 2.1 prior operations per hip. Twenty-two hips had American Academy... | ['Acetabulum', 'Adult', 'Aged', 'Female', 'Foreign-Body Migration', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Prosthesis Failure', 'Treatment Outcome'] | 7,673,909 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['M01.060.116.100'], ['C26.392.500'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767.865', 'E05.325.771'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of glutaraldehyde on cultured cells--restraining effect on multiplication of L cells]. | Glutaraldehyde (GA) was tested for its cytotoxic effect on L cell tissue culture system in comparison with formaldehyde (FA). In the first study, the replanted cells were grown to monolayers on the flattened bases of the culture tubes, and then exposed to the drug. In the second study, the drug was added to the cell su... | ['Aldehydes', 'Animals', 'Antineoplastic Agents', 'Cell Adhesion', 'Cells, Cultured', 'Depression, Chemical', 'Formaldehyde', 'Glutaral', 'L Cells', 'Mice', 'Mitosis'] | 3,095,205 | [['D02.047'], ['B01.050'], ['D27.505.954.248'], ['G04.022'], ['A11.251'], ['G07.690.773.750'], ['D02.047.407'], ['D02.047.532'], ['A11.251.210.505', 'A11.329.228.505'], ['B01.050.150.900.649.313.992.635.505.500'], ['G04.144.220.220.781', 'G05.113.220.781']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The anti-hypertensive drug prazosin induces apoptosis in the medullary thyroid carcinoma cell line TT. | BACKGROUND/AIM: Medullary thyroid carcinoma (MTC) is a tumor associated with poor prognosis since it exhibits high resistance against conventional cancer therapy. Recent studies have shown that quinazolines exhibit a pro-apoptotic effect on malignant cells. The aim of the present study was to elucidate whether MTC cell... | ['Antihypertensive Agents', 'Antineoplastic Agents', 'Apoptosis', 'Carcinoma, Medullary', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Humans', 'Prazosin', 'Receptors, Adrenergic, alpha-1', 'Thyroid Neoplasms'] | 25,550,532 | [['D27.505.954.411.162'], ['D27.505.954.248'], ['G04.146.954.035'], ['C04.557.465.625.650.240.315', 'C04.557.470.200.025.370.315', 'C04.557.470.615.315', 'C04.557.580.625.650.240.315'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First trimester contingent testing with either nuchal translucency or cell-free DNA. Cost efficiency and the role of ultrasound dating. | OBJECTIVE: To evaluate the performance and cost efficacy of different first-trimester contingent screening strategies based on an initial analysis of biochemical markers.DESIGN: Retrospective study.SETTING: Swedish National Quality Register for prenatal diagnosis.POPULATION: 35,780 women with singleton pregnancies.METH... | ['Adult', 'Aneuploidy', 'Biomarkers', 'Cell-Free System', 'Chromosome Disorders', 'Cost-Benefit Analysis', 'DNA', 'False Positive Reactions', 'Female', 'Genetic Markers', 'Gestational Age', 'Humans', 'Maternal Serum Screening Tests', 'Nuchal Translucency Measurement', 'Pregnancy', 'Pregnancy Trimester, First', 'Registr... | 25,581,307 | [['M01.060.116'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['D23.101'], ['A11.284.835.168'], ['C16.131.260', 'C16.320.180'], ['N03.219.151.125'], ['D13.444.308'], ['E01.354.506'], ['D23.101.387', 'G05.695.450'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Risk of Myocardial Infarction in Inflammatory Bowel Disease: A Population-based National Study. | BACKGROUND & OBJECTIVE: Chronic inflammation is linked to increased cardiovascular risk. Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract and elevated pro-inflammatory markers. The association between IBD and myocardial infarction (MI) is not well understood. We so... | ['Adult', 'Aged', 'Databases, Factual', 'Female', 'Follow-Up Studies', 'Humans', 'Inflammatory Bowel Diseases', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Ohio', 'Prevalence', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Young Adult'] | 30,500,938 | [['M01.060.116'], ['M01.060.116.100'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.205.731', 'C06.405.469.432'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Dietary Inadequacies Among US Homeless Families: An Enduring Problem. | We reviewed the literature on eating patterns, prevalent diet-related illnesses, barriers to healthy eating, and interventions to improve diet among the U.S. homeless family population. Our search returned 17 articles and one literature review. We found that families experiencing homelessness tend to have poor diets, l... | ['Anemia, Iron-Deficiency', 'Cooking', 'Dental Caries', 'Diet', 'Diet, Healthy', 'Family', 'Homeless Persons', 'Humans', 'Malnutrition', 'Nutritional Status', 'Overweight', 'United States'] | 30,449,741 | [['C15.378.071.196.300', 'C18.452.565.100'], ['J01.576.423.200.200'], ['C07.793.720.210'], ['G07.203.650.240'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['F01.829.263', 'I01.880.853.150'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.521'], ['G07.203.650.650', 'N01.224.425.525'], ['C23... | ['Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'G... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Prevalence of urinary incontinence and associated risk factors in postmenopausal women. Heart & Estrogen/Progestin Replacement Study (HERS) Research Group. | OBJECTIVE: To determine the prevalence of stress, urge, and mixed urinary incontinence and associated risk factors in postmenopausal women.METHODS: Before enrollment in a 4-year, randomized trial of combination hormone therapy to prevent coronary heart disease, 2763 participants completed questionnaires on prevalence a... | ['Aged', 'Estrogen Replacement Therapy', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Medroxyprogesterone Acetate', 'Postmenopause', 'Prevalence', 'Risk Factors', 'Urinary Incontinence'] | 10,389,720 | [['M01.060.116.100'], ['E02.319.452.150'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.829.395.700.500'], ['G08.686.157.500.625', 'G08.686.841.249.500.625'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Whole blood serotonin and tryptophan in autism: temporal stability and the effects of medication. | Whole blood serotonin (5-HT) was significantly increased in a drug-free autistic group (n = 17) compared to age- and sex-matched normal control (n = 20). Blood tryptophan (TRP) values and platelet counts were similar in unmedicated autistics and normal subjects; but whole blood concentrations of TRP were significantly ... | ['Adolescent', 'Adult', 'Anticonvulsants', 'Autistic Disorder', 'Female', 'Haloperidol', 'Humans', 'Male', 'Phenothiazines', 'Platelet Count', 'Serotonin', 'Time Factors', 'Tryptophan'] | 2,708,296 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.080'], ['F03.625.164.113.500'], ['D02.522.352.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.369', 'D03.633.300.783'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.195.107.740', 'E05.200.625.107... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A new generation of cyanide ion-selective membranes for flow injection application: part II. Comparative study of cyanide flow-injection detectors based on thin electroplated silver chalcogenide membranes. | Using induced cathodic electrodeposition a number of silver chalcogenide thin layer membranes of non-trivial composition have been synthesized and their performance as ion-selective flow-injection potentiometric detectors (FIPDs) for free cyanide has been critically estimated in the context of the stringent requirement... | ['Calibration', 'Chalcogens', 'Cyanides', 'Electrochemistry', 'Indicators and Reagents', 'Membranes, Artificial', 'Metals', 'Silver', 'Silver Compounds'] | 17,386,543 | [['E05.978.155'], ['D01.268.185'], ['D01.248.497.158.291', 'D01.625.400.100'], ['H01.181.529.307'], ['D27.720.470.410'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D01.552'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['D01.847']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Validation of Inertial Measurement Units for Upper Body Kinematics. | The purpose of this study was to validate a commercially available inertial measurement unit (IMU) system against a standard lab-based motion capture system for the measurement of shoulder elevation, elbow flexion, trunk flexion/extension, and neck flexion/extension kinematics. The validation analyses were applied to 6... | ['Adult', 'Biomechanical Phenomena', 'Elbow', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Movement', 'Neck', 'Range of Motion, Articular', 'Torso'] | 27,918,696 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['A01.378.800.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['E04.502'], ['G07.568', 'G11.427.410'], ['A01.598'], ['E01.370.600.700', 'G11.427.760'], ['A01.923']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants. | We have examined mutant lines of Chinese hamster ovary cells that have increased resistance to the antimicrotubule drug Colcemid. Analysis of the functional properties of purified microtubule protein indicates that increased tolerance to the drug in vivo is reflected in altered properties of microtubules and tubulin in... | ['Animals', 'Cells, Cultured', 'Cricetinae', 'Cricetulus', 'Demecolcine', 'Drug Resistance', 'Female', 'Isoelectric Point', 'Microtubules', 'Mutation', 'Ovary', 'Protein Binding', 'Tubulin'] | 6,946,501 | [['B01.050'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D03.132.225.374'], ['G07.690.773.984'], ['E05.301.300.663.500', 'G02.300.500'], ['A11.284.430.214.190.750.602'], ['G05.365.590'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Catheter ablation of paroxysmal atrial fibrillation using a 3D mapping system. | BACKGROUND: We treated paroxysmal recurrent atrial fibrillation (AF) with radiofrequency (RF) catheter ablation by creating long linear lesions in the atria. To achieve line continuity, a 3D electroanatomic nonfluoroscopic mapping system was used.METHODS AND RESULTS: In 27 patients with recurrent AF, a catheter incorpo... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Catheter Ablation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Recurrence', 'Treatment Outcome'] | 10,484,541 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.291.937'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antiarrhythmic effects of the quaternary propranolol analog that does not induce beta-adrenergic blockade. | Pranolium chloride (dimethylpropranolol chloride) is a nonbeta blocking quaternary ammonium that has structural similarities to propranolol and bretylium that exert antiarrhythmic effects in animals. In initial studies, eight patients with chronic ventricular arrhythmias were given gradually increasing intravenous dose... | ['Adult', 'Anti-Arrhythmia Agents', 'Arrhythmias, Cardiac', 'Dose-Response Relationship, Drug', 'Drug Evaluation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nausea', 'Propranolol'] | 7,083,729 | [['M01.060.116'], ['D27.505.954.411.097'], ['C14.280.067', 'C23.550.073'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.821.712'], ['D02.033.100.624.698.711', 'D02.033.755.624.698.711', 'D02.092.063.624.698.711', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid measurement of brain macromolecular proton fraction with transient saturation transfer MRI. | PURPOSE: To develop an efficient MRI approach to estimate the nonwater proton fraction (f) in human brain.METHODS: We implement a brief, efficient magnetization transfer (MT) pulse that selectively saturates the magnetization of the (semi-) solid protons, and monitor the transfer of this saturation to the water protons... | ['Adult', 'Algorithms', 'Brain', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Macromolecular Substances', 'Magnetic Resonance Imaging', 'Middle Aged', 'Molecular Imaging', 'Myelin Sheath', 'Proton Magnetic Resonance Spectroscopy', 'Reproducibility of Results', 'Sensitivity and Specificity'... | 27,342,121 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['D05'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.557', 'E05.601.555'], ['A08.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Muscle response to heavy resistance exercise in children with spastic cerebral palsy. | Fourteen ambulatory children with spastic diplegia participated in a bilateral quadriceps strengthening program in an attempt to decrease the amount of knee crouch during gait. Each child exercised three times a week for six weeks using free ankle weights at a load of 65 per cent of maximum. A normal comparison group o... | ['Adolescent', 'Biomechanical Phenomena', 'Cerebral Palsy', 'Child', 'Exercise Therapy', 'Female', 'Follow-Up Studies', 'Gait', 'Humans', 'Isometric Contraction', 'Male', 'Muscle Spasticity', 'Muscle, Skeletal'] | 7,672,470 | [['M01.060.057'], ['G01.154.090', 'G01.374.089'], ['C10.228.140.140.254'], ['M01.060.406'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ketoisophorone transformation by Marchantia polymorpha and Nicotiana tabacum cultured cells. | Stereospecific olefin (C=C) and carbonyl (C=O) reduction of the readily available prochiral compound ketoisophorone (2,2,6-trimethyl-2-cyclohexene-1,4-dione) (1) by Marchantia polymorpha and Nicotiana tabacum cell suspension cultures produce the chiral products (6R)-levodione (2), (4R,5S)-4-hydroxy-3,3,5-trimethylcyclo... | ['Cells, Cultured', 'Cyclohexanones', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Marchantia', 'Polymorphism, Genetic', 'Spectrum Analysis', 'Stereoisomerism', 'Tobacco'] | 18,669,027 | [['A11.251'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['B01.650.940.800.575.462.750'], ['G05.365.795'], ['E05.196.867'], ['G02.607.445.682'], ['B01.650.940.800.575.912.250.908.500.900']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life sentence. | Seven years ago nurse Dee Winzar was given a life sentence for murdering her husband Nic McCarthy. But a growing body of opinion says the verdict was unsafe. | ['Homicide', 'Humans', 'Prisoners', 'Spouses', 'United Kingdom'] | 18,087,874 | [['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.729'], ['F01.829.263.500.660', 'I01.880.853.150.500.670', 'M01.816'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Membrane oxidation assay--a novel lipoxygenase-based evaluation of membrane oxidizability. | A membrane oxidation assay is presented which uses isolated erythrocyte membranes ("ghosts") alipoxygenase as a selective catalyst for the transfer of oxygen to cis-cis-1,4-pentadiene-moieties. The latter are, for instance, present in linoleic and arachidonic acids, both of which are integral parts of membranes. These ... | ['Antioxidants', 'Arachidonic Acid', 'Blood Chemical Analysis', 'Cell Membrane', 'Cholesterol', 'Erythrocyte Membrane', 'Free Radicals', 'Humans', 'Lipoxygenase', 'Oxygen', 'Oxygen Consumption', 'Time Factors'] | 12,747,735 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['E01.370.225.124.100', 'E05.200.124.100'], ['A11.284.149'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity. | AlphaII-spectrin is a major cortical cytoskeletal protein contributing to membrane organization and integrity. The Ca2+-activated binding of calmodulin to an unstructured insert in the 11th repeat unit of alphaII-spectrin enhances the susceptibility of spectrin to calpain cleavage but abolishes its sensitivity to sever... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Calmodulin', 'Calpain', 'Cattle', 'Circular Dichroism', 'Crystallography, X-Ray', 'Humans', 'Molecular Sequence Data', 'Protein Binding', 'Protein Conformation', 'Sequence Homology, Amino Acid', 'Spectrin'] | 16,945,920 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D08.811.277.656.262.500.120', 'D08.811.277.656.300.200.120'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.867.151'], ['E05.196.309.742.225'], ['B01.050.150.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cytotoxicity and DNA damage associated with pyrazoloacridine in MCF-7 breast cancer cells. | We examined the effects of pyrazoloacridine (PZA), an investigational anticancer agent in clinical trials, on cytotoxicity, DNA synthesis, and DNA damage in MCF-7 human breast carcinoma cells. With PZA concentrations ranging from 0.5 to 50 microM for durations of 3-72 hr, cytotoxicity increased in proportion to the tot... | ['Acridines', 'Antineoplastic Agents', 'Breast Neoplasms', 'Carcinoma', 'Cell Count', 'DNA', 'Dose-Response Relationship, Drug', 'Electrophoresis', 'Female', 'Humans', 'Pyrazoles', 'Time Factors'] | 8,687,480 | [['D03.633.300.046'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.12... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of mobile laminar airflow units on airborne bacterial contamination during neurosurgical procedures. | BACKGROUND: Surgical site infections (SSIs) after neurosurgery are potentially life-threatening and entail great costs. SSIs may occur from airborne bacteria in the operating room, and ultraclean air is desired during infection-prone cleaning procedures. Door openings and the number of persons present in the operating ... | ['Air Microbiology', 'Bacteria', 'Colony Count, Microbial', 'Environment, Controlled', 'Humans', 'Mobile Health Units', 'Neurosurgical Procedures', 'Non-Randomized Controlled Trials as Topic'] | 29,580,895 | [['H01.158.273.540.274.110', 'N06.850.425.110'], ['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.230.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.421.702', 'N02.421.726.233.628'], ['E04.525'], ['E05.318.372.250.250.365.250', 'N05.715.360.330.250.250.365.250', 'N06.850.520.450.250.250.365... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of surface potential on aggregation and transport of titania nanoparticles. | To investigate the effect of pH on nanoparticle aggregation and transport in porous media, we quantified nanoparticle transport in two-dimensional structures. Titania was used as a model compound to explore the effects of surface potential on particle mobility in the subsurface. Results show that pH, and therefore, sur... | ['Chromatography, High Pressure Liquid', 'Hydrogen-Ion Concentration', 'Nanoparticles', 'Surface Properties', 'Titanium'] | 17,256,514 | [['E05.196.181.400.300'], ['G02.300'], ['J01.637.512.600'], ['G02.860'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Irreversible inhibition of glutamate decarboxylase by alpha-(fluoromethyl)glutamic acid. | alpha-(Fluoromethyl)glutamic acid (FMG) was synthesized and shown to be an active site directed irreversible inhibitor of glutamate decarboxylase (EC 4.1.1.15) from Escherichia coli. The KI for the active enantiomer is 1.4 microM, and the kinh = 5.9 X 10(-3) s-1. Substrates for the enzyme, such as L-glutamate, and comp... | ['Binding, Competitive', 'Carbon Radioisotopes', 'Carboxy-Lyases', 'Citrates', 'Escherichia coli', 'Glutamate Decarboxylase', 'Glutamates', 'Kinetics', 'Spectrophotometry', 'Tritium'] | 7,011,364 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D08.811.520.224.125'], ['D02.241.081.901.434'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.520.224.125.250'], ['D12.125.067.625', 'D12.125.119.409'], ['G01.374.661', 'G02.111.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the absence of the detrusor muscle in initial transurethral resected specimens and the presence of residual tumor tissue. | OBJECTIVE: To investigate the relationship between surgeon's experience, tumor characteristics, absent detrusor muscle (DM) tissue in resected specimens, and residual tumor after an initial transurethral resection.PATIENTS AND METHODS: We conducted an analysis of 216 patients from two centers over a 3-year period. Pati... | ['Aged', 'Female', 'Humans', 'Male', 'Medical Oncology', 'Middle Aged', 'Multivariate Analysis', 'Muscle, Smooth', 'Neoplasm, Residual', 'Odds Ratio', 'Reproducibility of Results', 'Treatment Outcome', 'Urethra', 'Urinary Bladder Neoplasms', 'Urology'] | 22,922,447 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['A02.633.570', 'A10.690.467'], ['C04.697.700', 'C23.550.727.700'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.... | ['Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenosine action on interneurons and synaptic transmission onto interneurons in rat hippocampus in vitro. | To investigate the action of adenosine on interneurons as well as on excitatory synaptic transmission onto interneurons in the hippocampus, intracellular recordings were made from electrophysiologically identified interneurons in the CA1 region of the hippocampal slice in vitro. The effects of adenosine and the prefere... | ['2-Chloroadenosine', 'Adenosine', 'Animals', 'Anti-Arrhythmia Agents', 'Hippocampus', 'Interneurons', 'Male', 'Membrane Potentials', 'Purinergic P1 Receptor Agonists', 'Pyramidal Cells', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Purinergic P1', 'Synaptic Transmission'] | 11,068,019 | [['D03.633.100.759.590.138.300', 'D13.570.583.138.300', 'D13.570.800.096.300'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['D27.505.954.411.097'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['A08.675.358', 'A11.671.358'], ['G01.154.535', 'G04.580', 'G07.265.675', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphometry of the optic nerve and retinal vessels in children by computer-assisted image analysis of fundus photographs. | BACKGROUND: The retinal fundus in childhood has a different morphology than in adulthood. Existing methods are not suitable for evaluation of fundus photographs from children. Therefore, a new method for quantitative analysis of fundus morphology utilizing a personal computer-assisted digital mapping system was develop... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Fetal Alcohol Spectrum Disorders', 'Fundus Oculi', 'Humans', 'Image Processing, Computer-Assisted', 'Observer Variation', 'Optic Disk', 'Optic Nerve', 'Photography', 'Reproducibility of Results', 'Retinal Vessels', 'Sensitivity and Specificity'] | 7,758,982 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C13.703.277.220', 'C16.300.070', 'C25.775.100.087.323'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['A08.800.800.120.6... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The role of cultural models in local perceptions of SFM--differences and similarities of interest groups from three boreal regions. | Differences in the way local and regional interest groups perceive Sustainable Forest Management in regions with different forest use histories were studied using Southeastern Finland, the Mauricie in Quebec and Central Labrador in Canada as examples of regions with high, medium and low importance of commercial forestr... | ['Cultural Characteristics', 'Finland', 'Models, Theoretical', 'Newfoundland and Labrador', 'Quebec', 'Trees'] | 18,321,636 | [['I01.076.201.450.324', 'I01.880.853.100.329'], ['Z01.542.816.186'], ['E05.599'], ['Z01.107.567.176.540'], ['Z01.107.567.176.791'], ['B01.650.915']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
A study on household headship, living arrangement, and recipient of pension among the older adults in association with suicidal risks. | BACKGROUND: This study aims to examine whether variation in socioeconomic factors indicative of lower status within families in later life, such as the elderly losing their household headship, living with descendants, and having no pension are associated with suicidal risks among the older adults aged 60 years and abov... | ['Aged', 'Cross-Sectional Studies', 'Family Characteristics', 'Family Relations', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pensions', 'Regression Analysis', 'Residence Characteristics', 'Socioeconomic Factors', 'Suicide'] | 31,299,443 | [['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A survey of resident perspectives on surgical case minimums and the impact on milestones, graduation, credentialing, and preparation for practice: AOA critical issues. | Residency education continues to evolve. Several major changes have occurred in the past several years, including emphasis on core competencies, duty-hour restrictions, and call. The Accreditation Council for Graduate Medical Education (ACGME) Next Accreditation System (NAS) implemented educational milestones in orthop... | ['Attitude of Health Personnel', 'Clinical Competence', 'Credentialing', 'Data Collection', 'Education, Medical, Graduate', 'Humans', 'Internship and Residency', 'Orthopedics', 'Personnel Staffing and Scheduling', 'United States', 'Workload'] | 25,471,921 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N03.706.110', 'N05.700.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Pneumonia eosinofilic in pediatrics, clinical cases. | INTRODUCTION: Eosinophilic Pneumonia (EP) is a very rare disorder in Pediatrics. It is characterized by the infiltra tion of eosinophils in the pulmonary and alveolar interstitium, and may be primary or secondary as well as present an acute or chronic progress.OBJECTIVE: to present 2 pediatric EP clinical cases which w... | ['Biopsy', 'Bronchoalveolar Lavage', 'Eosinophilia', 'Humans', 'Infant', 'Lung', 'Male', 'Oxygen', 'Pneumonia, Viral', 'Pulmonary Eosinophilia', 'Respiration, Artificial', 'Respiratory Insufficiency'] | 32,186,589 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.927.100'], ['C15.378.553.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A04.411'], ['D01.268.185.550', 'D01.362.670'], ['C01.748.610.763', 'C0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Multimodal approach to postoperative analgesia in patients with neuropathic pain]. | Chronic neuropathic pain syndrome observed prior to surgery not only influences the intensity of pain, but also reduces the efficiency of selective use of analgesics. The purpose of the investigation was to study the efficiency of various analgesics and their combinations after lumbar microdiskectomy. Seventy-six patie... | ['Adult', 'Analgesics', 'Back Pain', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Humans', 'Intervertebral Disc Displacement', 'Male', 'Pain Measurement', 'Pain, Postoperative', 'Time Factors', 'Treatment Outcome'] | 19,102,243 | [['M01.060.116'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['C23.888.592.612.107'], ['E02.319.283'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['E01.370.600.550.324'], ['C23.550.767.700', 'C23.888.592.612.832'], ['G01.910.857'], ['E01.789.800', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Demonstrating the pharmacogenetic effects of angiotensin-converting enzyme inhibitors on long-term prognosis of diastolic heart failure. | The objective of this study was to evaluate the effects of angiotensin-converting enzyme (ACE) inhibitors and pharmacogenetic interaction on the survival of the patients with diastolic heart failure (DHF). A total of 285 subjects with DHF confirmed by echocardiography were recruited in the period between 1995 and 2003.... | ['Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Female', 'Follow-Up Studies', 'Gene Deletion', 'Heart Failure, Diastolic', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Mutagenesis, Insertional', 'Peptidyl-Dipeptidase A', 'Polymorphism, Genetic', 'Prognosis', 'Propensity Score', 'Prospective Studies'... | 19,752,885 | [['M01.060.116.100'], ['D27.505.519.389.745.085'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.365.590.762.320', 'G05.558.800.320'], ['C14.280.434.611'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Allosteric communication between signal peptides and the SecA protein DEAD motor ATPase domain. | SecA, the preprotein translocase ATPase is built of an amino-terminal DEAD helicase motor domain bound to a regulatory C-domain. SecA recognizes mature and signal peptide preprotein regions. We now demonstrate that the amino-terminal 263 residues of the ATPase subdomain of the DEAD motor are necessary and sufficient fo... | ['Adenosine Triphosphatases', 'Allosteric Site', 'Bacterial Proteins', 'Binding Sites', 'Cross-Linking Reagents', 'Cytoplasm', 'Escherichia coli Proteins', 'Kinetics', 'Membrane Transport Proteins', 'Models, Genetic', 'Mutation', 'Protein Binding', 'Protein Conformation', 'Protein Sorting Signals', 'Protein Structure, ... | 11,825,907 | [['D08.811.277.040.025'], ['G02.111.570.120.147'], ['D12.776.097'], ['G02.111.570.120'], ['D27.720.470.410.210'], ['A11.284.430.214'], ['D12.776.097.275'], ['G01.374.661', 'G02.111.490'], ['D12.776.157.530', 'D12.776.543.585'], ['E05.599.395.397'], ['G05.365.590'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Reactivation of Escherichia coli inactivated by ultraviolet light by cell extracts of propionic acid bacteria]. | For the first time reactivation of cell extract of three strains of Propionibacterium shermanii in UV inactivated not filament-forming strain Escherichia colli AB 1157 is shown. Reactivation was demonstrated in preincubated and postincubated test-culture and increased as survival of E. coli decreased in a range 1.8-0.0... | ['Carbon', 'Culture Media', 'Dialysis', 'Enzymes', 'Escherichia coli', 'Propionibacterium', 'Species Specificity', 'Temperature', 'Ultraviolet Rays'] | 8,114,646 | [['D01.268.150'], ['D27.720.470.305', 'E07.206'], ['E05.196.353', 'G02.186'], ['D08.811'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.510.024.990.600', 'B03.510.460.400.400.600.600'], ['G16.824'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.72... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ca2+- and calmodulin-dependent stimulation of smooth muscle actomyosin Mg2+-ATPase by fodrin. | Fodrin, a spectrin-like actin and calmodulin binding protein, was purified to electrophoretic homogeneity from a membrane fraction of bovine brain. The effect of fodrin on smooth muscle actomyosin Mg2+-ATPase activity was examined by using a system reconstituted from skeletal muscle actin and smooth muscle myosin and r... | ['Actins', 'Actomyosin', 'Animals', 'Brain', 'Ca(2+) Mg(2+)-ATPase', 'Calcium', 'Calmodulin', 'Carrier Proteins', 'Cattle', 'Chickens', 'Gizzard, Avian', 'Kinetics', 'Microfilament Proteins', 'Muscle, Smooth', 'Myosins', 'Nerve Tissue Proteins', 'Rabbits'] | 2,952,165 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.776.210.500.154'], ['B01.050'], ['A08.186.211'], ['D08.811.277.040.025.095'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157'], ['B01.050.150.900... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Additive effect of cyclooxygenase and nitric oxide synthase blockade on the cerebrocortical microcirculation. | The contribution of vasodilator cyclooxygenase (COX) metabolites to the maintenance of the cerebrocortical blood flow (CBF) has been studied under physiological conditions and in nitric oxide (NO) deficiency. Inhibition of COX decreased resting CBF without changing arterial blood pressure. NO synthase blockade resulted... | ['Animals', 'Blood Pressure', 'Cerebral Cortex', 'Cerebrovascular Circulation', 'Cyclooxygenase Inhibitors', 'Dinoprostone', 'Enzyme Inhibitors', 'Epoprostenol', 'Hypertension', 'Indomethacin', 'Male', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Prostaglandin-Endoperoxide Synthases', 'Ran... | 19,579,269 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.186.211.200.885.287.500'], ['G09.330.100.159'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.500'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D27.505.519.389'], ['D10... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhanced solubility, stability, and transcorneal permeability of ä-8-tetrahydrocannabinol in the presence of cyclodextrins. | The purpose of this study was to investigate the effect of cyclodextrins (CDs) on aqueous solubility, stability, and in vitro corneal permeability of delta-8-tetrahydrocannabinol (Ä(8)-THC). Phase solubility of Ä(8)-THC was studied in the presence of 2-hydroxypropyl-â-cyclodextrin (HPâCD), randomly methylated-â-cyclode... | ['Administration, Topical', 'Animals', 'Cornea', 'Cyclodextrins', 'Dronabinol', 'Drug Carriers', 'Drug Stability', 'Male', 'Permeability', 'Rabbits', 'Solubility'] | 21,637,944 | [['E02.319.267.120'], ['B01.050'], ['A09.371.060.217'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D02.455.849.090.810'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.330'], ['G02.723'], ['B01.050.150.900.649.313.968.700'], ['G02.805']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin-28B rs12979860C/T and rs8099917T/G contribute to spontaneous clearance of hepatitis C virus in Caucasians. | Two single nucleotide polymorphisms rs12979860C/T and rs8099917T/G around interleukin-28B (IL28B) locus have been extensively investigated in their association with hepatitis C virus (HCV) spontaneous clearance. However, with the variable and even inconsistent results, it is necessary to conduct a meta-analysis. A lite... | ['European Continental Ancestry Group', 'Genetic Variation', 'Genotype', 'Hepacivirus', 'Hepatitis C', 'Hepatitis C, Chronic', 'Humans', 'Interferons', 'Interleukins', 'Polymorphism, Single Nucleotide', 'Remission, Spontaneous', 'Viral Load'] | 23,266,640 | [['M01.686.508.400'], ['G05.365'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of three models of saccade disconjugacy in strabismus. | In pattern strabismus the horizontal and vertical misalignments vary with eye position along the orthogonal axis. The disorder is typically described in terms of overaction or underaction of oblique muscles. Recent behavioral studies in humans and monkeys, however, have reported that such actions are insufficient to fu... | ['Animals', 'Evoked Potentials, Visual', 'Macaca mulatta', 'Models, Neurological', 'Saccades', 'Strabismus'] | 28,904,108 | [['B01.050'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E05.599.395.642'], ['G14.350.500'], ['C10.292.562.887', 'C11.590.810']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disability in post-earthquake Haiti: prevalence and inequality in access to services. | PURPOSE: To assess the prevalence of disability and service needs in post-earthquake Haiti, and to compare the inclusion and living conditions of people with disabilities to those without disabilities.METHODS: A population-based prevalence survey of disability was undertaken in 2012 in Port-au-Prince region, which was ... | ['Adolescent', 'Adult', 'Age Distribution', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Disabled Children', 'Earthquakes', 'Employment', 'Family Characteristics', 'Female', 'Haiti', 'Health Services Needs and Demand', 'Healthcare Disparities', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate ... | 25,178,862 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['M01.150.200'], ['G01.311.250', 'N06.230.100.230.200'], ['N01.824.245'], ['F01.829.263.315', 'I01.240.361', 'I01... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Impaired relaxation of the human mammary artery after temporary clamping. | Internal mammary artery specimens from 17 patients were each divided into three separate rings. One ring (control) remained in Krebs solution and the other two were clamped for 30 minutes with either a soft or hard jaw clamp. Isometric tensions were measured in an organ chamber by contracting the rings twice with a thr... | ['Acetylcholine', 'Constriction', 'Endothelium, Vascular', 'Humans', 'In Vitro Techniques', 'Mammary Arteries', 'Muscle Relaxation', 'Myocardial Revascularization', 'Nitroprusside', 'Papaverine', 'Prostaglandin Endoperoxides, Synthetic'] | 1,405,697 | [['D02.092.211.111'], ['E05.225'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A07.015.114.891.525'], ['G11.427.494.554'], ['E04.100.376.719', 'E04.928.220.520'], ['D01.248.497.158.291.350.550', 'D01.490.100.300.550', 'D01.625.400.100.325.550'], ['D03.132.098.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Onset and persistence of daily smoking: the interplay of socioeconomic status, gender, and psychiatric disorders. | UNLABELLED: Gains in reducing the prevalence of smoking observed over the past 40 years have been substantially lower among lower socioeconomic status (SES) groups and women. In parallel, there have been strong and consistent associations of psychiatric disorders with SES, gender, and smoking. Yet few studies have exam... | ['Adolescent', 'Adult', 'Age of Onset', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Longitudinal Studies', 'Male', 'Mental Disorders', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Sex Factors', 'Smoking', 'Smoking Cessation', 'Social Class', 'United States', 'Young Adult'] | 19,487,086 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Ozone tolerance in lichens: a possible explanation from biochemical to physiological level using Flavoparmelia caperata as test organism. | Lichens are among the best biomonitors of airborne pollutants, but surprisingly they reveal high tolerance to ozone (O3). It was recently suggested that this might be due to the high levels of natural defences against oxidative stress, related to their poikilohydric life strategy. The objective of this work is to give ... | ['Antioxidants', 'Chlorophyll', 'Chlorophyll A', 'Desiccation', 'Fluorescence', 'Humidity', 'Italy', 'Lichens', 'Organ Specificity', 'Oxidants, Photochemical', 'Ozone', 'Reactive Oxygen Species', 'Water'] | 25,105,236 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['E05.196.335', 'G02.176'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G16.500.275.063.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Self-report INH adherence measures were reliable and valid in Latino adolescents with latent tuberculosis infection. | BACKGROUND AND OBJECTIVE: To test the reliability and validity of 8-day and 30-day self-report measures of adherence to daily isoniazid (INH) for treatment of latent tuberculosis infection (LTBI).METHODS: Participants were 286 Latino adolescents (ages 13-18, 55.6% male) with LTBI recruited from 10 public middle and hig... | ['Adolescent', 'Adolescent Behavior', 'Antitubercular Agents', 'Disclosure', 'Female', 'Hispanic Americans', 'Humans', 'Isoniazid', 'Male', 'Patient Compliance', 'Reproducibility of Results', 'Tuberculosis'] | 15,878,479 | [['M01.060.057'], ['F01.145.022'], ['D27.505.954.122.085.255'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Thrombotic risk factors in patients with antiphospholipid syndrome: a single center experience. | Patients with primary or secondary antiphospholipid syndrome (APS) have an increased risk of recurrent venous, arterial thrombosis and pregnancy complications. Therefore, determining thrombotic risk is important when individualizing antithrombotic therapy in patients with APS. To identify thrombotic risk factors in a c... | ['Adult', 'African Continental Ancestry Group', 'Anticoagulants', 'Antiphospholipid Syndrome', 'Autoimmune Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Precision Medicine', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Thrombosis'] | 30,835,035 | [['M01.060.116'], ['M01.686.508.100'], ['D27.505.954.502.119'], ['C20.111.197'], ['C20.111'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.782', 'H02.403.200.700'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Nutritional aspects in allogeneic hematopoietic stem cell transplantation in children and adolescents in a tertiary hospital. | Introduction: Introduction: during hematopoietic stem cell transplantation (HSCT) some factors may impact on the patient's nutritional status (NS). Conditioning regimen, as well as signs and symptoms of the gastrointestinal tract, can negatively infl uence on oral food intake. Patients may require the use of complement... | ['Adolescent', 'Child', 'Child, Preschool', 'Energy Intake', 'Enteral Nutrition', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Nutritional Status', 'Nutritional Support', 'Parenteral Nutrition', 'Retrospective Studies', 'Tertiary Care Centers', 'Transplantation, H... | 30,816,791 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['G07.203.650.240.340'], ['E02.421.360', 'E02.642.500.360'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['G07.203.650.650', 'N01.224.425.525'], ['E02.642.500'], ['E02.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neoplastic transformation-associated stimulation of the in vitro resolution of concatemer junction fragments from minute virus of mice DNA. | Minute virus of mice (MVM) shows an oncotropic behavior reflected by its ability to amplify its genome more efficiently in a number of transformed versus normal cells. In vivo and in vitro studies revealed that the major effect of cell transformation on MVM DNA replication occurs at the level of double-stranded replica... | ['Cell Transformation, Neoplastic', 'DNA Replication', 'DNA, Viral', 'Gene Amplification', 'Humans', 'Minute Virus of Mice', 'Virus Replication'] | 9,971,842 | [['C04.697.098.500', 'C23.550.727.098.500'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.280.580.650.600.550'], ['G06.920.925']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glycaemic index values in the Finnish food composition database: an approach to standardised value documentation. | BACKGROUND/OBJECTIVES: The glycaemic index (GI) is used to describe the blood glucose-raising potential of carbohydrate-containing foods. Only a few descriptions of the addition of GI values to national food composition databases (FCDBs) exist. We tested whether the value documentation framework established within the ... | ['Blood Glucose', 'Databases, Factual', 'Dietary Carbohydrates', 'Documentation', 'Finland', 'Food', 'Food Analysis', 'Glycemic Index', 'Humans', 'Reference Standards', 'Surveys and Questionnaires'] | 21,045,854 | [['D09.947.875.359.448.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['L01.453.245'], ['Z01.542.816.186'], ['G07.203.300', 'J02.500'], ['E05.362', 'J01.576.423.850.100'], ['G07.203.650.660.500', 'J01.576.423.850.730.750.500', 'N06.850.601.750.500'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Upright face-preferential high-gamma responses in lower-order visual areas: evidence from intracranial recordings in children. | Behavioral studies demonstrate that a face presented in the upright orientation attracts attention more rapidly than an inverted face. Saccades toward an upright face take place in 100-140 ms following presentation. The present study using electrocorticography determined whether upright face-preferential neural activat... | ['Adolescent', 'Child', 'Electric Stimulation', 'Electrocorticography', 'Evoked Potentials, Visual', 'Facial Recognition', 'Female', 'Gamma Rhythm', 'Humans', 'Male', 'Photic Stimulation', 'Visual Cortex'] | 25,579,446 | [['M01.060.057'], ['M01.060.406'], ['E05.723.402'], ['E01.370.376.300.294', 'E01.370.405.245.431'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['F02.463.593.524.250.500', 'F02.463.593.524.500.500', 'F02.463.593.932.622.500'], ['E01.370.376.300.150.906', 'E01.370.405.245.287.906', 'G07.265.087.906', 'G11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture. | Epithelial cell adhesion molecule (EpCAM) is overexpressed in most solid cancers and is an ideal antigen for clinical applications in cancer diagnosis, prognosis, imaging, and therapy. Currently, most of the EpCAM-based diagnostic, prognostic, and therapeutic strategies rely on the anti-EpCAM antibody. However, the use... | ['Antigens, Neoplasm', 'Aptamers, Nucleotide', 'Biomarkers, Tumor', 'Cell Adhesion Molecules', 'Cell Line, Tumor', 'Epithelial Cell Adhesion Molecule', 'Female', 'Flow Cytometry', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Gene Expression', 'Humans', 'Inverted Repeat Sequences', 'Neoplastic Stem Cells', 'Opti... | 23,480,100 | [['D23.050.285'], ['D13.695.578.424.224'], ['D23.101.140'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.395.550.200.263', 'D12.776.543.550.200.263', 'D23.050.285.357', 'D23.050.301.350.263'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Patterns of intracranial glioblastoma recurrence after aggressive surgical resection and adjuvant management: retrospective analysis of 43 cases. | The present retrospective study evaluated the recurrence patterns after aggressive surgical removal of intracranial glioblastomas in 43 consecutive adult patients. The resection rate of the enhanced lesion on magnetic resonance imaging was 100% and 95-99% in 22 and 21 cases, respectively. All patients received postoper... | ['Adolescent', 'Adult', 'Aged', 'Brain Neoplasms', 'Cancer Vaccines', 'Chemoradiotherapy, Adjuvant', 'Combined Modality Therapy', 'Female', 'Glioblastoma', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Retrospective Studies', 'Survival Analysis', 'Young Adult'] | 22,976,141 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D20.215.894.200'], ['E02.186.079.500', 'E02.319.164.500', 'E02.815.160.500'], ['E02.186'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel COL7A1 gene mutation causing pretibial epidermolysis bullosa: report of a Chinese family with intra-familial phenotypical diversity. | Pretibial epidermolysis bullosa (PEB) is an extremely rare subtype of dominant dystrophic epidermolysis bullosa (DDEB) caused by mutation of the COL7A1 gene. More than 730 mutations have been identified in patients with DDEB, but only five mutations have been found to be related to PEB. In this study, a novel heterozyg... | ['Adolescent', 'Adult', 'Amino Acid Substitution', 'Asian Continental Ancestry Group', 'Child', 'Collagen Type VII', 'Epidermolysis Bullosa Dystrophica', 'Exons', 'Female', 'Humans', 'Inheritance Patterns', 'Male', 'Middle Aged', 'Mutation', 'Pedigree', 'Phenotype', 'Severity of Illness Index', 'Young Adult'] | 23,624,125 | [['M01.060.057'], ['M01.060.116'], ['E05.393.420.601.035', 'G05.558.109'], ['M01.686.508.200'], ['M01.060.406'], ['D12.776.860.300.250.400.300'], ['C16.131.831.493.160', 'C16.320.850.275.160', 'C17.300.200.367', 'C17.800.804.493.160', 'C17.800.827.275.160', 'C17.800.865.410.160'], ['G05.360.340.024.340.137.232'], ['B01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues. | A series of tricyclic analogues of acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine substituted in the 6 position with thien-2-yl, 5-bromothien-2-yl or furan-2-yl group were synthesized. The new compounds 5a-f were evaluated for their activity in vitro against varicella-zoster virus (VZV) an... | ['Acyclovir', 'Antiviral Agents', 'Cell Line', 'Guanine', 'Herpesvirus 3, Human', 'Humans'] | 19,339,082 | [['D03.633.100.759.758.399.454.250'], ['D27.505.954.122.388'], ['A11.251.210'], ['D03.633.100.759.758.399.454'], ['B04.280.382.100.900.460'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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