Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Chemokine interleukin-8-like

Disordered

Low complexity

Polar residues

Basic and acidic residues

Initial sequencing and analysis of the human genome.

Humphray S.J.
Oliver K.
Hunt A.R.
Plumb R.W.
Loveland J.E.
Howe K.L.
Andrews T.D.
Searle S.
Hunt S.E.
Scott C.E.
Jones M.C.
Ainscough R.
Almeida J.P.
Ambrose K.D.
Ashwell R.I.
Babbage A.K.
Babbage S.
Bagguley C.L.
Bailey J.
Banerjee R.
Barker D.J.
Barlow K.F.
Bates K.
Beasley H.
Beasley O.
Bird C.P.
Bray-Allen S.
Brown A.J.
Brown J.Y.
Burford D.
Burrill W.
Burton J.
Carder C.
Carter N.P.
Chapman J.C.
Chen Y.
Clarke G.
Clark S.Y.
Clee C.M.
Clegg S.
Collier R.E.
Corby N.
Crosier M.
Cummings A.T.
Davies J.
Dhami P.
Dunn M.
Dutta I.
Dyer L.W.
Earthrowl M.E.
Faulkner L.
Fleming C.J.
Frankish A.
Frankland J.A.
French L.
Fricker D.G.
Garner P.
Garnett J.
Ghori J.
Gilbert J.G.
Glison C.
Grafham D.V.
Gribble S.
Griffiths C.
Griffiths-Jones S.
Grocock R.
Guy J.
Hall R.E.
Hammond S.
Harley J.L.
Harrison E.S.
Hart E.A.
Heath P.D.
Henderson C.D.
Hopkins B.L.
Howard P.J.
Howden P.J.
Huckle E.
Johnson C.
Johnson D.
Joy A.A.
Kay M.
Keenan S.
Kershaw J.K.
Kimberley A.M.
King A.
Knights A.
Laird G.K.
Langford C.
Lawlor S.
Leongamornlert D.A.
Leversha M.
Lloyd C.
Lloyd D.M.
Lovell J.
Martin S.
Mashreghi-Mohammadi M.
Matthews L.
McLaren S.
McLay K.E.
McMurray A.
Milne S.
Nickerson T.
Nisbett J.
Nordsiek G.
Pearce A.V.
Peck A.I.
Porter K.M.
Pandian R.
Pelan S.
Phillimore B.
Povey S.
Ramsey Y.
Rand V.
Scharfe M.
Sehra H.K.
Shownkeen R.
Sims S.K.
Skuce C.D.
Smith M.
Steward C.A.
Swarbreck D.
Sycamore N.
Tester J.
Thorpe A.
Tracey A.
Tromans A.
Thomas D.W.
Wall M.
Wallis J.M.
West A.P.
Whitehead S.L.
Willey D.L.
Williams S.A.
Wilming L.
Wray P.W.
Young L.
Ashurst J.L.
Coulson A.
Blocker H.
Durbin R.
Sulston J.E.
Hubbard T.
Jackson M.J.
Bentley D.R.
Beck S.
Rogers J.
Dunham I.

DNA sequence and analysis of human chromosome 9.

Finishing the euchromatic sequence of the human genome.


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca


Eukaryota Metazoa Hemichordata Enteropneusta Harrimaniidae

BHLH

PAS

PAS

Disordered

Basic and acidic residues

Belato F.A.
Mello B.
Coates C.J.
Halanych K.M.
Brown F.D.
Morandini A.C.
Leme J.M.
Trindade R.I.F.
Costa-Paiva E.M.

Divergence time estimates for the hypoxia-inducible factor-1 alpha (HIF1a) reveal an ancient emergence of animals in low-oxygen environments.

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1 subunit alpha

Hypoxia-inducible factor 1-alpha isoform 1

hypoxia-inducible factor 3-alpha isoform X1

HLH, helix-loop-helix DNA-binding domain


Helical

Helical

Helical

Helical

Helical

Helical

Helical

Disordered

Basic and acidic residues

Rhodopsin 7-helix transmembrane proteins

Family A G protein-coupled receptor-like


Nucleophile

Zhong J.
Gao Y.M.
Mo C.P.
Zhang Y.
Li L.B.
Wei S.T.
Li T.Y.

Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A

HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE

Belongs to the glycosyltransferase 6 family


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Polychaeta Echiura Xenopneusta Urechidae Urechis

Heat shock protein family A member 12 variant X6

F:ATP-dependent protein folding chaperone

Belongs to the heat shock protein 70 family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes

Helical

Helical

Helical

Helical

Pathak J.
Thiruvengadam V.
Gracy G.R.
M M.


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Coleoptera Polyphaga Cucujiformia Curculionidae Scolytinae Hypothenemus

RRM

RRM

Genetic variation in Jamaican populations of the coffee berry borer (Hypothenemus hampei).

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

De novo transcriptome assembly of the two larval stages of Hypothenemus hampei as a tool for identification of candidate genes for RNAi.

P:negative regulation of gene expression

P:negative regulation of mRNA processing

P:positive regulation of signal transduction


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Helical

Helical

Helical

Helical

Helical

Helical

Helical

G-protein coupled receptors family 1 profile

Genome insights into chemosensory and detoxification machineries of broad mite, Polyphagotarsonemus latus (Tarsonemidae: Acari).

CHOLECYSTOKININ-LIKE RECEPTOR AT 17D1-RELATED

Belongs to the G-protein coupled receptor 1 family


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Aplacophora Caudofoveata Chaetodermatida Prochaetodermatidae Spathoderma

BHLH

PAS

PAS

Disordered

Disordered

Low complexity

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1-alpha isoform 1

HLH, helix-loop-helix DNA-binding domain


von Willebrand factor A domain-containing protein-like protein

VWFA

EGF-like

EGF-like

EGF-like

EGF-like

VWFA

VWFA

Disordered

Disordered

Disordered

Pro residues

Basic and acidic residues

Basic and acidic residues

Low complexity

Lacks conserved residue(s) required for the propagation of feature annotation


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Stenopodainae Oncocephalus

CUB

Disordered

Zdenek C.N.
Cardoso F.C.
Robinson S.D.
Mercedes R.S.
Raidjoe E.R.
Hernandez-Vargas M.J.
Jin J.
Corzo G.
Vetter I.
King G.F.
Fry B.G.
Walker A.

Venom adaptation and exaptation during the trophic switch to blood-feeding by kissing bugs (Reduviidae: Triatominae).


Eukaryota Metazoa Porifera Calcarea Calcinea Clathrinida Leucettidae Leucetta

BZIP

Gene networks governing the response of a calcareous sponge to future ocean conditions reveal lineage-specific XBP1 regulation of the unfolded protein response.


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Zygaenoidea Megalopygidae Megalopyge

Pyrrolidone carboxylic acid

Threonine amide

Walker A.A.
Robinson S.D.
Merritt D.J.
Cardoso F.C.
Goudarzi M.H.
Mercedes R.S.
Eagles D.A.
Cooper P.
Zdenek C.N.
Fry B.G.
Hall D.W.
Vetter I.
King G.F.

Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae).

NUCLEOTIDE SEQUENCE [MRNA]
MASS SPECTROMETRY
SYNTHESIS OF 26-55
PYROGLUTAMATE FORMATION AT GLN-26
AMIDATION AT THR-55
SUBCELLULAR LOCATION
TISSUE SPECIFICITY
DEVELOPMENTAL STAGE


NUCLEOTIDE SEQUENCE [MRNA]
MASS SPECTROMETRY
SUBCELLULAR LOCATION
TISSUE SPECIFICITY
DEVELOPMENTAL STAGE


Bacteria
Pseudomonadati
Chlamydiota
Chlamydiia
Chlamydiales
Chlamydiaceae
Chlamydia/Chlamydophila group
Chlamydia

T-Q ester bond containing

Disordered

Polar residues

Intramolecular ester bond-containing repeat domain from Chlamydia trachomatis adhesin.

X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH CA(2+)


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Ostariophysi Cypriniformes Danionidae Danioninae Danio

Cilia- and flagella-associated protein 184 isoform X1

CCDC113/CCDC96 coiled-coil

Disordered

Acidic residues

Polar residues

Acidic residues

Howe K.
Clark M.D.
Torroja C.F.
Torrance J.
Berthelot C.
Muffato M.
Collins J.E.
Humphray S.
McLaren K.
Matthews L.
McLaren S.
Sealy I.
Caccamo M.
Churcher C.
Scott C.
Barrett J.C.
Koch R.
Rauch G.J.
White S.
Chow W.
Kilian B.
Quintais L.T.
Guerra-Assuncao J.A.
Zhou Y.
Gu Y.
Yen J.
Vogel J.H.
Eyre T.
Redmond S.
Banerjee R.
Chi J.
Fu B.
Langley E.
Maguire S.F.
Laird G.K.
Lloyd D.
Kenyon E.
Donaldson S.
Sehra H.
Almeida-King J.
Loveland J.
Trevanion S.
Jones M.
Quail M.
Willey D.
Hunt A.
Burton J.
Sims S.
McLay K.
Plumb B.
Davis J.
Clee C.
Oliver K.
Clark R.
Riddle C.
Elliot D.
Eliott D.
Threadgold G.
Harden G.
Ware D.
Begum S.
Mortimore B.
Mortimer B.
Kerry G.
Heath P.
Phillimore B.
Tracey A.
Corby N.
Dunn M.
Johnson C.
Wood J.
Clark S.
Pelan S.
Griffiths G.
Smith M.
Glithero R.
Howden P.
Barker N.
Lloyd C.
Stevens C.
Harley J.
Holt K.
Panagiotidis G.
Lovell J.
Beasley H.
Henderson C.
Gordon D.
Auger K.
Wright D.
Collins J.
Raisen C.
Dyer L.
Leung K.
Robertson L.
Ambridge K.
Leongamornlert D.
McGuire S.
Gilderthorp R.
Griffiths C.
Manthravadi D.
Nichol S.
Barker G.
Whitehead S.
Kay M.
Brown J.
Murnane C.
Gray E.
Humphries M.
Sycamore N.
Barker D.
Saunders D.
Wallis J.
Babbage A.
Hammond S.
Mashreghi-Mohammadi M.
Barr L.
Martin S.
Wray P.
Ellington A.
Matthews N.
Ellwood M.
Woodmansey R.
Clark G.
Cooper J.
Cooper J.
Tromans A.
Grafham D.
Skuce C.
Pandian R.
Andrews R.
Harrison E.
Kimberley A.
Garnett J.
Fosker N.
Hall R.
Garner P.
Kelly D.
Bird C.
Palmer S.
Gehring I.
Berger A.
Dooley C.M.
Ersan-Urun Z.
Eser C.
Geiger H.
Geisler M.
Karotki L.
Kirn A.
Konantz J.
Konantz M.
Oberlander M.
Rudolph-Geiger S.
Teucke M.
Lanz C.
Raddatz G.
Osoegawa K.
Zhu B.
Rapp A.
Widaa S.
Langford C.
Yang F.
Schuster S.C.
Carter N.P.
Harrow J.
Ning Z.
Herrero J.
Searle S.M.
Enright A.
Geisler R.
Plasterk R.H.
Lee C.
Westerfield M.
de Jong P.J.
Zon L.I.
Postlethwait J.H.
Nusslein-Volhard C.
Hubbard T.J.
Roest Crollius H.
Rogers J.
Stemple D.L.

The zebrafish reference genome sequence and its relationship to the human genome.

COILED-COIL DOMAIN-CONTAINING PROTEIN 113-RELATED

COILED-COIL DOMAIN-CONTAINING PROTEIN 96


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Eupercaria Sciaenidae Argyrosomus

Genetic markers of meagre immune system activation.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae Saxifragales Paeoniaceae Paeonia

Disordered

B3 DOMAIN-CONTAINING PROTEIN REM-LIKE 3-RELATED

B3 DOMAIN-CONTAINING PROTEIN REM14-RELATED


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Aplacophora Solenogastres Pholidoskepia Meiomeniidae Meiomenia

PAS

PAS

Disordered

Disordered

Disordered

Polar residues

Low complexity

Polar residues

Basic and acidic residues


BZIP

Disordered

Disordered

Low complexity

Basic and acidic residues

Basic and acidic residues


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Noctuoidea Erebidae Lymantriinae Lymantria

ETS

Disordered

Disordered

Disordered

Disordered

Basic and acidic residues

Basic and acidic residues

Low complexity

Basic residues

F:DNA-binding transcription activator activity, RNA polymerase II-specific

P:regulation of development, heterochronic

Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain


Helical

Helical

Helical

Helical

Helical

Disordered

Low complexity

F:dopamine neurotransmitter receptor activity, coupled via Gi/Go

Rhodopsin 7-helix transmembrane proteins

ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR

Family A G protein-coupled receptor-like

Belongs to the G-protein coupled receptor 1 family


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Rosales Elaeagnaceae Hippophae

Peptidase S26

Peptidase S26

Zhao J.
Xu Y.
Zhang Z.
Zhao M.
Li K.
Wang F.
Sun K.

Genome-wide analysis of the MADS-box gene family of sea buckthorn (Hippophae rhamnoides ssp. sinensis) and their potential role in floral organ development.

C:mitochondrial inner membrane peptidase complex

P:protein processing involved in protein targeting to mitochondrion

MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1-LIKE

PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space

Heterodimer of 2 subunits, IMP1A/B and IMP12

Belongs to the peptidase S26 family. IMP1 subfamily


Cystatin

F:cysteine-type endopeptidase inhibitor activity


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Hadeninae Mythimna

Helical

Helical

Helical

Helical

Identification and sex expression profiles of olfactory-related genes in Mythimna loreyi based on antennal transcriptome analysis.


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Whippomorpha Cetacea Mysticeti Eschrichtiidae Eschrichtius

Bruniche-Olsen A.
Black A.N.
Fields C.J.
Walden K.
Dewoody J.A.

Whole genome sequence of Eschrichtius robustus ER-17-0199.

F:DNA-binding transcription factor activity

F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

P:regulation of transcription by RNA polymerase II

May be involved in transcriptional regulation

Belongs to the krueppel C2H2-type zinc-finger protein family

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca

FZ

Mikhailov K.
Kravchuk O.
Lyupina Y.
Adameyko K.

Lacks conserved residue(s) required for the propagation of feature annotation


CUB

Disordered

Basic and acidic residues


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Integrin beta subunit VWA

International Human Genome Sequencing Consortium

Lander E.S.
Linton L.M.
Birren B.
Nusbaum C.
Zody M.C.
Baldwin J.
Devon K.
Dewar K.
Doyle M.
FitzHugh W.
Funke R.
Gage D.
Harris K.
Heaford A.
Howland J.
Kann L.
Lehoczky J.
LeVine R.
McEwan P.
McKernan K.
Meldrim J.
Mesirov J.P.
Miranda C.
Morris W.
Naylor J.
Raymond C.
Rosetti M.
Santos R.
Sheridan A.
Sougnez C.
Stange-Thomann N.
Stojanovic N.
Subramanian A.
Wyman D.
Rogers J.
Sulston J.
Ainscough R.
Beck S.
Bentley D.
Burton J.
Clee C.
Carter N.
Coulson A.
Deadman R.
Deloukas P.
Dunham A.
Dunham I.
Durbin R.
French L.
Grafham D.
Gregory S.
Hubbard T.
Humphray S.
Hunt A.
Jones M.
Lloyd C.
McMurray A.
Matthews L.
Mercer S.
Milne S.
Mullikin J.C.
Mungall A.
Plumb R.
Ross M.
Shownkeen R.
Sims S.
Waterston R.H.
Wilson R.K.
Hillier L.W.
McPherson J.D.
Marra M.A.
Mardis E.R.
Fulton L.A.
Chinwalla A.T.
Pepin K.H.
Gish W.R.
Chissoe S.L.
Wendl M.C.
Delehaunty K.D.
Miner T.L.
Delehaunty A.
Kramer J.B.
Cook L.L.
Fulton R.S.
Johnson D.L.
Minx P.J.
Clifton S.W.
Hawkins T.
Branscomb E.
Predki P.
Richardson P.
Wenning S.
Slezak T.
Doggett N.
Cheng J.F.
Olsen A.
Lucas S.
Elkin C.
Uberbacher E.
Frazier M.
Gibbs R.A.
Muzny D.M.
Scherer S.E.
Bouck J.B.
Sodergren E.J.
Worley K.C.
Rives C.M.
Gorrell J.H.
Metzker M.L.
Naylor S.L.
Kucherlapati R.S.
Nelson D.L.
Weinstock G.M.
Sakaki Y.
Fujiyama A.
Hattori M.
Yada T.
Toyoda A.
Itoh T.
Kawagoe C.
Watanabe H.
Totoki Y.
Taylor T.
Weissenbach J.
Heilig R.
Saurin W.
Artiguenave F.
Brottier P.
Bruls T.
Pelletier E.
Robert C.
Wincker P.
Smith D.R.
Doucette-Stamm L.
Rubenfield M.
Weinstock K.
Lee H.M.
Dubois J.
Rosenthal A.
Platzer M.
Nyakatura G.
Taudien S.
Rump A.
Yang H.
Yu J.
Wang J.
Huang G.
Gu J.
Hood L.
Rowen L.
Madan A.
Qin S.
Davis R.W.
Federspiel N.A.
Abola A.P.
Proctor M.J.
Myers R.M.
Schmutz J.
Dickson M.
Grimwood J.
Cox D.R.
Olson M.V.
Kaul R.
Raymond C.
Shimizu N.
Kawasaki K.
Minoshima S.
Evans G.A.
Athanasiou M.
Schultz R.
Roe B.A.
Chen F.
Pan H.
Ramser J.
Lehrach H.
Reinhardt R.
McCombie W.R.
de la Bastide M.
Dedhia N.
Blocker H.
Hornischer K.
Nordsiek G.
Agarwala R.
Aravind L.
Bailey J.A.
Bateman A.
Batzoglou S.
Birney E.
Bork P.
Brown D.G.
Burge C.B.
Cerutti L.
Chen H.C.
Church D.
Clamp M.
Copley R.R.
Doerks T.
Eddy S.R.
Eichler E.E.
Furey T.S.
Galagan J.
Gilbert J.G.
Harmon C.
Hayashizaki Y.
Haussler D.
Hermjakob H.
Hokamp K.
Jang W.
Johnson L.S.
Jones T.A.
Kasif S.
Kaspryzk A.
Kennedy S.
Kent W.J.
Kitts P.
Koonin E.V.
Korf I.
Kulp D.
Lancet D.
Lowe T.M.
McLysaght A.
Mikkelsen T.
Moran J.V.
Mulder N.
Pollara V.J.
Ponting C.P.
Schuler G.
Schultz J.
Slater G.
Smit A.F.
Stupka E.
Szustakowski J.
Thierry-Mieg D.
Thierry-Mieg J.
Wagner L.
Wallis J.
Wheeler R.
Williams A.
Wolf Y.I.
Wolfe K.H.
Yang S.P.
Yeh R.F.
Collins F.
Guyer M.S.
Peterson J.
Felsenfeld A.
Wetterstrand K.A.
Patrinos A.
Morgan M.J.
de Jong P.
Catanese J.J.
Osoegawa K.
Shizuya H.
Choi S.
Chen Y.J.

Hillier L.W.
Graves T.A.
Fulton R.S.
Fulton L.A.
Pepin K.H.
Minx P.
Wagner-McPherson C.
Layman D.
Wylie K.
Sekhon M.
Becker M.C.
Fewell G.A.
Delehaunty K.D.
Miner T.L.
Nash W.E.
Kremitzki C.
Oddy L.
Du H.
Sun H.
Bradshaw-Cordum H.
Ali J.
Carter J.
Cordes M.
Harris A.
Isak A.
van Brunt A.
Nguyen C.
Du F.
Courtney L.
Kalicki J.
Ozersky P.
Abbott S.
Armstrong J.
Belter E.A.
Caruso L.
Cedroni M.
Cotton M.
Davidson T.
Desai A.
Elliott G.
Erb T.
Fronick C.
Gaige T.
Haakenson W.
Haglund K.
Holmes A.
Harkins R.
Kim K.
Kruchowski S.S.
Strong C.M.
Grewal N.
Goyea E.
Hou S.
Levy A.
Martinka S.
Mead K.
McLellan M.D.
Meyer R.
Randall-Maher J.
Tomlinson C.
Dauphin-Kohlberg S.
Kozlowicz-Reilly A.
Shah N.
Swearengen-Shahid S.
Snider J.
Strong J.T.
Thompson J.
Yoakum M.
Leonard S.
Pearman C.
Trani L.
Radionenko M.
Waligorski J.E.
Wang C.
Rock S.M.
Tin-Wollam A.M.
Maupin R.
Latreille P.
Wendl M.C.
Yang S.P.
Pohl C.
Wallis J.W.
Spieth J.
Bieri T.A.
Berkowicz N.
Nelson J.O.
Osborne J.
Ding L.
Meyer R.
Sabo A.
Shotland Y.
Sinha P.
Wohldmann P.E.
Cook L.L.
Hickenbotham M.T.
Eldred J.
Williams D.
Jones T.A.
She X.
Ciccarelli F.D.
Izaurralde E.
Taylor J.
Schmutz J.
Myers R.M.
Cox D.R.
Huang X.
McPherson J.D.
Mardis E.R.
Clifton S.W.
Warren W.C.
Chinwalla A.T.
Eddy S.R.
Marra M.A.
Ovcharenko I.
Furey T.S.
Miller W.
Eichler E.E.
Bork P.
Suyama M.
Torrents D.
Waterston R.H.
Wilson R.K.

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

Belongs to the integrin beta chain family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Hymenoptera Apocrita Aculeata Formicoidea Formicidae Myrmicinae Pogonomyrmex

Glutamine amide

Robinson S.D.
Deuis J.R.
Niu P.
Touchard A.
Mueller A.
Schendel V.
Brinkwirth N.
King G.F.
Vetter I.
Schmidt J.O.

Peptide toxins that target vertebrate voltage-gated sodium channels underly the painful stings of harvester ants.

NUCLEOTIDE SEQUENCE [MRNA]
IDENTIFICATION BY MASS SPECTROMETRY
SUBCELLULAR LOCATION
SYNTHESIS OF 34-60
BIOASSAY
TOXIC DOSE
AMIDATION AT GLN-60

Toxin that causes a rapid and irreversible paralysis when intrathoracically injected into insects (blowflies). Does not cause spontaneous nocifensive behaviors by intraplantar injection in mice

PD(50) [1 hour] is 43.7 nmol/g when intrathoracically injected into insects (blowfly L.caesar)

Negative results: does not exhibit hemolytic and cytotoxic activities on HEK293 cells

Belongs to the formicidae venom clade 2 family


Deleted in malignant brain tumors 1 protein-like protein 1

Helical

SRCR

SRCR

SRCR

SRCR

SRCR

SRCR

Scavenger receptor cysteine-rich protein type 12


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Liliales Liliaceae Lilium

Protein TIFY

Tify

Disordered

P:regulation of jasmonic acid mediated signaling pathway

The jas domain is required for interaction with COI1


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Auchenorrhyncha Fulgoroidea Delphacidae Delphacinae Sogatella

Glycoside hydrolase family 20 catalytic

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Belongs to the glycosyl hydrolase 20 family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Polyneoptera Orthoptera Ensifera Gryllidea Grylloidea Gryllidae Gryllinae Gryllus

Ion transport peptide and ion transport peptide-like regulate ecdysis behavior and water transport during ecdysis in Gryllus bimaculatus.

Belongs to the arthropod CHH/MIH/GIH/VIH hormone family


IF rod

LTD

Disordered

Disordered

Polar residues

Acidic residues

Intermediate filament protein, coiled coil region


Eukaryota Metazoa Ecdysozoa Arthropoda Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Brachyura Eubrachyura Potamoidea Potamidae Paratelphusula

Helical

Shi B.Y.
Pan D.
Zhang K.Q.
Gu T.Y.
Yeo D.C.J.
Ng P.K.L.
Cumberlidge N.
Sun H.Y.

Diversification of freshwater crabs on the sky islands in the Hengduan Mountains Region, China.

Rhodopsin 7-helix transmembrane proteins


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes

Helical

Helical

Helical

Helical

Helical

Helical

Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Stenopodainae Oncocephalus

Calcineurin-like phosphoesterase

a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Epithelial sodium channel/degenerin-like protein

Helical

Disordered

Disordered

Low complexity

Low complexity

Basic and acidic residues

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Ranoidea Ranidae Nidirana

Zheng P.
Gong Y.
Wang B.
Yu H.
Huang S.
Liao X.
Jiang J.
Ran J.
Xie F.

Love Hug-Functional Validation of Nuptial Pad-Secreted Pheromone in Anurans.


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus

Helical

axial binding residue

Selvamani S.B.
Negi N.
Nagarjuna Reddy K.V.
Ramasamy G.G.

Identification of Cytochrome P450s in Maconellicoccus hirsutus.

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Asparagales Orchidaceae Epidendroideae Gastrodieae Gastrodia

P:regulation of DNA-templated transcription

Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1

Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs)


Helical

Helical


Elongation factor 1 beta central acidic region eukaryote

Disordered

Acidic residues

Augustine N.
Selvapandian U.
Muthugoundar M.

Evaluation of reference genes for expression studies in the broad mite, Polyphagotarsonemus latus (Acari: Tarsonemidae).

C:eukaryotic translation elongation factor 1 complex

F:guanyl-nucleotide exchange factor activity

F:translation elongation factor activity

EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Zygentoma Lepismatidae Thermobia

HTH psq-type

HTH psq-type

H-T-H motif

H-T-H motif

Disordered

Disordered

Disordered

Disordered

Disordered

Disordered

Disordered

Low complexity

Polar residues

Polar residues

Polar residues

Basic residues

Basic and acidic residues

Basic and acidic residues

Low complexity

Polar residues

Basic and acidic residues

Acidic residues

Polar residues

P:regulation of transcription by RNA polymerase II


Neonatal crystallizable Fc receptor FcRn splice variant 6

Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles.


axial binding residue

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Peiratinae Ectomocoris


Helical

Helical

Helical

Helical

Helical

Helical

Helical

Genome insights into chemosensory and detoxification machineries of broad mite, Polyphagotarsonemus latus (Tarsonemidae: Acari).

P:adenylate cyclase-activating adrenergic receptor signaling pathway

ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR

Family A G protein-coupled receptor-like

Belongs to the G-protein coupled receptor 1 family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Thysanoptera Terebrantia Thripoidea Thripidae Thrips

Belongs to the major royal jelly protein family


Eukaryota Metazoa Ecdysozoa Arthropoda Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Brachyura Eubrachyura Portunoidea Portunidae Portuninae Scylla

Disordered

Disordered

Polar residues

Basic and acidic residues

Polar residues


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Polychaeta Echiura Xenopneusta Urechidae Urechis

Heat shock protein family A member 14 variant X1

F:ATP-dependent protein folding chaperone

Substrate Binding Domain Of DNAk, Chain A, domain 1

Heat shock protein 70kD (HSP70), peptide-binding domain

Belongs to the heat shock protein 70 family


axial binding residue

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Zygaenoidea Limacodidae Comana

Goudarzi M.H.
Robinson S.D.
Cardoso F.C.
Mitchell M.L.
Cook L.G.
King G.F.
Walker A.A.

Phylogeny, envenomation syndrome, and membrane-permeabilising venom produced by Australia's 'electric' caterpillar Comana monomorpha (Lepidoptera: Limacodidae).


Eukaryota Metazoa Porifera Calcarea Calcinea Clathrinida Leucettidae Leucetta

BZIP

Disordered

Gene networks governing the response of a calcareous sponge to future ocean conditions reveal lineage-specific XBP1 regulation of the unfolded protein response.

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Coleoptera Polyphaga Cucujiformia Nitidulidae Nitidulinae Aethina

Cyclic GMP-AMP synthase-like receptor

Disordered

Polar residues

Evans J.
Huang Q.
Sim S.B.
Corpuz R.L.
Simmonds T.J.
Childers A.
Kuhn K.
Smith T.
Geib S.M.

Chromosome-scale assembly of Aethina tumida.

Li Y.
Slavik K.M.
Toyoda H.C.
Morehouse B.R.
de Oliveira Mann C.C.
Elek A.
Levy S.
Wang Z.
Mears K.S.
Liu J.
Kashin D.
Guo X.
Mass T.
Sebe-Pedros A.
Schwede F.
Kranzusch P.J.

cGLRs are a diverse family of pattern recognition receptors in innate immunity.

F:2',3'-cyclic GMP-AMP synthase activity

CELL FATE DETERMINING PROTEIN MAB21-RELATED

CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED

Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity (PubMed:37379839). Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses (PubMed:37379839). Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the immune response via activation of the NF-kappa-B transcription factor (PubMed:37379839)

pppGp(2'-5')A = 2',3'-cGAMP + diphosphate


Bacteria Bacillati Actinomycetota Actinomycetes Micrococcales Microbacteriaceae Microbacterium

3'-dehydrocarminate deglycosidase beta subunit

Mori T.
Kumano T.
He H.
Watanabe S.
Senda M.
Moriya T.
Adachi N.
Hori S.
Terashita Y.
Kawasaki M.
Hashimoto Y.
Awakawa T.
Senda T.
Abe I.
Kobayashi M.

C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.

NUCLEOTIDE SEQUENCE [GENOMIC DNA]
FUNCTION
CATALYTIC ACTIVITY
COFACTOR
ACTIVITY REGULATION
BIOPHYSICOCHEMICAL PROPERTIES
SUBUNIT

Carbon-carbon bond-cleaving enzyme which participates in a carminate degradation pathway (PubMed:34728636). Cleaves the C-C bond in 3'-dehydrocarminate to form kermesate (PubMed:34728636). Also shows weak activity with other C-glycosides, such as 3''-dehydropuerarin (3''-oxo-puerarin), 3''-dehydroisoorientin (3''-oxo-homoorientin) and 3'-dehydromangiferin (3'-oxo-mangiferin) (PubMed:34728636)

3'-dehydrocarminate + H(+) = kermesate + 1,5-anhydro-D-erythro-hex-1-en-3-ulose

Activity is strongly reduced in the presence of chelating agents

kcat is 23 min(-1) with 3'-dehydrocarminate as substrate. kcat is 0.12 min(-1) with 3''-dehydropuerarin as substrate. kcat is 0.024 min(-1) with 3''-dehydroisoorientin as substrate. kcat is 0.16 min(-1) with 3'-dehydromangiferin as substrate.

Optimum temperature is around 40 degrees Celsius.

Heterodimer composed of an alpha subunit (CarB) and a beta subunit (CarC)

Belongs to the C-glycoside deglycosidase beta subunit family


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Adaptor related protein complex 4 subunit mu 1

Initial sequencing and analysis of the human genome.

Hillier L.W.
Fulton R.S.
Fulton L.A.
Graves T.A.
Pepin K.H.
Wagner-McPherson C.
Layman D.
Maas J.
Jaeger S.
Walker R.
Wylie K.
Sekhon M.
Becker M.C.
O'Laughlin M.D.
Schaller M.E.
Fewell G.A.
Delehaunty K.D.
Miner T.L.
Nash W.E.
Cordes M.
Du H.
Sun H.
Edwards J.
Bradshaw-Cordum H.
Ali J.
Andrews S.
Isak A.
Vanbrunt A.
Nguyen C.
Du F.
Lamar B.
Courtney L.
Kalicki J.
Ozersky P.
Bielicki L.
Scott K.
Holmes A.
Harkins R.
Harris A.
Strong C.M.
Hou S.
Tomlinson C.
Dauphin-Kohlberg S.
Kozlowicz-Reilly A.
Leonard S.
Rohlfing T.
Rock S.M.
Tin-Wollam A.M.
Abbott A.
Minx P.
Maupin R.
Strowmatt C.
Latreille P.
Miller N.
Johnson D.
Murray J.
Woessner J.P.
Wendl M.C.
Yang S.P.
Schultz B.R.
Wallis J.W.
Spieth J.
Bieri T.A.
Nelson J.O.
Berkowicz N.
Wohldmann P.E.
Cook L.L.
Hickenbotham M.T.
Eldred J.
Williams D.
Bedell J.A.
Mardis E.R.
Clifton S.W.
Chissoe S.L.
Marra M.A.
Raymond C.
Haugen E.
Gillett W.
Zhou Y.
James R.
Phelps K.
Iadanoto S.
Bubb K.
Simms E.
Levy R.
Clendenning J.
Kaul R.
Kent W.J.
Furey T.S.
Baertsch R.A.
Brent M.R.
Keibler E.
Flicek P.
Bork P.
Suyama M.
Bailey J.A.
Portnoy M.E.
Torrents D.
Chinwalla A.T.
Gish W.R.
Eddy S.R.
McPherson J.D.
Olson M.V.
Eichler E.E.
Green E.D.
Waterston R.H.
Wilson R.K.

The DNA sequence of human chromosome 7.

Finishing the euchromatic sequence of the human genome.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Lycopodiopsida Lycopodiales Lycopodiaceae Huperzioideae Huperzia

Disordered

Disordered

Lei M.
Li C.
Zhang Z.-j.
Ou X.-l.
Chen X.-y.

F:DNA-binding transcription factor activity

AP2-like ethylene-responsive transcription factor

AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR

ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR RAP2-7

Belongs to the AP2/ERF transcription factor family. AP2 subfamily


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Microhyloidea Brevicipitidae Breviceps

Galectin

Recurrent evolution of adhesive defence systems in amphibians by parallel shifts in gene expression.


Eukaryota Metazoa Spiralia Lophotrochozoa Brachiopoda Rhynchonelliformea Rhynchonellata Rhynchonellida Hemithiridoidea Hemithyrididae Hemithiris

BHLH

PAS

PAS

Disordered

Disordered

Basic and acidic residues

Polar residues

Belato F.A.
Mello B.
Coates C.J.
Halanych K.M.
Brown F.D.
Morandini A.C.
Leme J.M.
Trindade R.I.F.
Costa-Paiva E.M.

Divergence time estimates for the hypoxia-inducible factor-1 alpha (HIF1a) reveal an ancient emergence of animals in low-oxygen environments.

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1-alpha isoform 1

HLH, helix-loop-helix DNA-binding domain


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Coleoptera Polyphaga Cucujiformia Curculionidae Curculioninae Anthonomini Anthonomus

Helical

Segura Leon O.L.
Lechuga-Paredes P.
Cibrian Tovar J.
Torres Huerta B.

Lechuga-Paredes P.
Segura-Leon O.L.
Cibrian-Tovar J.
Torres-Huerta B.
Velazquez-Gonzalez J.C.
Cruz-Jaramillo J.L.

Odorant-Binding and Chemosensory Proteins in Anthonomus eugenii (Coleoptera: Curculionidae) and Their Tissue Expression.

Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3

EJACULATORY BULB-SPECIFIC PROTEIN 3-RELATED


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Polyneoptera Orthoptera Ensifera Tettigoniidea Tettigonioidea Tettigoniidae Tettigoniinae Anabrus

DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase

ENPP1-3/EXOG-like endonuclease/phosphodiesterase

Proton acceptor

F:single-stranded DNA endodeoxyribonuclease activity

Belongs to the DNA/RNA non-specific endonuclease family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus

Cytochrome P450 - CYP3636A1 short isoform

Helical

Helical

Disordered

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes

Helical

Pathak J.
Thiruvengadam V.
Gracy G.R.
M M.


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca

Importin N-terminal

Disordered

Acidic residues

Mikhailov K.
Kravchuk O.
Lyupina Y.
Adameyko K.


Helical

axial binding residue


Helical

Helical


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Ostariophysi Cypriniformes Danionidae Danioninae Danio

Phenazine biosynthesis-like domain-containing protein

Howe K.
Clark M.D.
Torroja C.F.
Torrance J.
Berthelot C.
Muffato M.
Collins J.E.
Humphray S.
McLaren K.
Matthews L.
McLaren S.
Sealy I.
Caccamo M.
Churcher C.
Scott C.
Barrett J.C.
Koch R.
Rauch G.J.
White S.
Chow W.
Kilian B.
Quintais L.T.
Guerra-Assuncao J.A.
Zhou Y.
Gu Y.
Yen J.
Vogel J.H.
Eyre T.
Redmond S.
Banerjee R.
Chi J.
Fu B.
Langley E.
Maguire S.F.
Laird G.K.
Lloyd D.
Kenyon E.
Donaldson S.
Sehra H.
Almeida-King J.
Loveland J.
Trevanion S.
Jones M.
Quail M.
Willey D.
Hunt A.
Burton J.
Sims S.
McLay K.
Plumb B.
Davis J.
Clee C.
Oliver K.
Clark R.
Riddle C.
Elliot D.
Eliott D.
Threadgold G.
Harden G.
Ware D.
Begum S.
Mortimore B.
Mortimer B.
Kerry G.
Heath P.
Phillimore B.
Tracey A.
Corby N.
Dunn M.
Johnson C.
Wood J.
Clark S.
Pelan S.
Griffiths G.
Smith M.
Glithero R.
Howden P.
Barker N.
Lloyd C.
Stevens C.
Harley J.
Holt K.
Panagiotidis G.
Lovell J.
Beasley H.
Henderson C.
Gordon D.
Auger K.
Wright D.
Collins J.
Raisen C.
Dyer L.
Leung K.
Robertson L.
Ambridge K.
Leongamornlert D.
McGuire S.
Gilderthorp R.
Griffiths C.
Manthravadi D.
Nichol S.
Barker G.
Whitehead S.
Kay M.
Brown J.
Murnane C.
Gray E.
Humphries M.
Sycamore N.
Barker D.
Saunders D.
Wallis J.
Babbage A.
Hammond S.
Mashreghi-Mohammadi M.
Barr L.
Martin S.
Wray P.
Ellington A.
Matthews N.
Ellwood M.
Woodmansey R.
Clark G.
Cooper J.
Cooper J.
Tromans A.
Grafham D.
Skuce C.
Pandian R.
Andrews R.
Harrison E.
Kimberley A.
Garnett J.
Fosker N.
Hall R.
Garner P.
Kelly D.
Bird C.
Palmer S.
Gehring I.
Berger A.
Dooley C.M.
Ersan-Urun Z.
Eser C.
Geiger H.
Geisler M.
Karotki L.
Kirn A.
Konantz J.
Konantz M.
Oberlander M.
Rudolph-Geiger S.
Teucke M.
Lanz C.
Raddatz G.
Osoegawa K.
Zhu B.
Rapp A.
Widaa S.
Langford C.
Yang F.
Schuster S.C.
Carter N.P.
Harrow J.
Ning Z.
Herrero J.
Searle S.M.
Enright A.
Geisler R.
Plasterk R.H.
Lee C.
Westerfield M.
de Jong P.J.
Zon L.I.
Postlethwait J.H.
Nusslein-Volhard C.
Hubbard T.J.
Roest Crollius H.
Rogers J.
Stemple D.L.

The zebrafish reference genome sequence and its relationship to the human genome.

Diaminopimelate Epimerase, Chain A, domain 1

PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Peiratinae Ectomocoris

Peptidase S1


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Chondrostei Acipenseriformes Acipenseridae Acipenser

Belongs to the alpha/beta interferon family


Eukaryota Metazoa Ecdysozoa Arthropoda Crustacea Multicrustacea Malacostraca Eumalacostraca Peracarida Isopoda Oniscidea Crinocheta Paraplatyarthridae Paraplatyarthrus

cellulase

Glycoside hydrolase family 9

Javidkar M.
Cooper S.J.B.
Shokri Bousjein N.
Humphreys W.F.
King R.A.
Austin A.D.

Evolution of endoglucanase genes in subterranean and surface isopod crustaceans from Central Western Australia.

F:hydrolase activity, hydrolyzing O-glycosyl compounds

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Belongs to the glycosyl hydrolase 9 (cellulase E) family


Bone morphogenetic protein receptor type 1A

Helical

Activin types I and II receptor

Lander E.S.
Linton L.M.
Birren B.
Nusbaum C.
Zody M.C.
Baldwin J.
Devon K.
Dewar K.
Doyle M.
FitzHugh W.
Funke R.
Gage D.
Harris K.
Heaford A.
Howland J.
Kann L.
Lehoczky J.
LeVine R.
McEwan P.
McKernan K.
Meldrim J.
Mesirov J.P.
Miranda C.
Morris W.
Naylor J.
Raymond C.
Rosetti M.
Santos R.
Sheridan A.
Sougnez C.
Stange-Thomann N.
Stojanovic N.
Subramanian A.
Wyman D.
Rogers J.
Sulston J.
Ainscough R.
Beck S.
Bentley D.
Burton J.
Clee C.
Carter N.
Coulson A.
Deadman R.
Deloukas P.
Dunham A.
Dunham I.
Durbin R.
French L.
Grafham D.
Gregory S.
Hubbard T.
Humphray S.
Hunt A.
Jones M.
Lloyd C.
McMurray A.
Matthews L.
Mercer S.
Milne S.
Mullikin J.C.
Mungall A.
Plumb R.
Ross M.
Shownkeen R.
Sims S.
Waterston R.H.
Wilson R.K.
Hillier L.W.
McPherson J.D.
Marra M.A.
Mardis E.R.
Fulton L.A.
Chinwalla A.T.
Pepin K.H.
Gish W.R.
Chissoe S.L.
Wendl M.C.
Delehaunty K.D.
Miner T.L.
Delehaunty A.
Kramer J.B.
Cook L.L.
Fulton R.S.
Johnson D.L.
Minx P.J.
Clifton S.W.
Hawkins T.
Branscomb E.
Predki P.
Richardson P.
Wenning S.
Slezak T.
Doggett N.
Cheng J.F.
Olsen A.
Lucas S.
Elkin C.
Uberbacher E.
Frazier M.
Gibbs R.A.
Muzny D.M.
Scherer S.E.
Bouck J.B.
Sodergren E.J.
Worley K.C.
Rives C.M.
Gorrell J.H.
Metzker M.L.
Naylor S.L.
Kucherlapati R.S.
Nelson D.L.
Weinstock G.M.
Sakaki Y.
Fujiyama A.
Hattori M.
Yada T.
Toyoda A.
Itoh T.
Kawagoe C.
Watanabe H.
Totoki Y.
Taylor T.
Weissenbach J.
Heilig R.
Saurin W.
Artiguenave F.
Brottier P.
Bruls T.
Pelletier E.
Robert C.
Wincker P.
Smith D.R.
Doucette-Stamm L.
Rubenfield M.
Weinstock K.
Lee H.M.
Dubois J.
Rosenthal A.
Platzer M.
Nyakatura G.
Taudien S.
Rump A.
Yang H.
Yu J.
Wang J.
Huang G.
Gu J.
Hood L.
Rowen L.
Madan A.
Qin S.
Davis R.W.
Federspiel N.A.
Abola A.P.
Proctor M.J.
Myers R.M.
Schmutz J.
Dickson M.
Grimwood J.
Cox D.R.
Olson M.V.
Kaul R.
Raymond C.
Shimizu N.
Kawasaki K.
Minoshima S.
Evans G.A.
Athanasiou M.
Schultz R.
Roe B.A.
Chen F.
Pan H.
Ramser J.
Lehrach H.
Reinhardt R.
McCombie W.R.
de la Bastide M.
Dedhia N.
Blocker H.
Hornischer K.
Nordsiek G.
Agarwala R.
Aravind L.
Bailey J.A.
Bateman A.
Batzoglou S.
Birney E.
Bork P.
Brown D.G.
Burge C.B.
Cerutti L.
Chen H.C.
Church D.
Clamp M.
Copley R.R.
Doerks T.
Eddy S.R.
Eichler E.E.
Furey T.S.
Galagan J.
Gilbert J.G.
Harmon C.
Hayashizaki Y.
Haussler D.
Hermjakob H.
Hokamp K.
Jang W.
Johnson L.S.
Jones T.A.
Kasif S.
Kaspryzk A.
Kennedy S.
Kent W.J.
Kitts P.
Koonin E.V.
Korf I.
Kulp D.
Lancet D.
Lowe T.M.
McLysaght A.
Mikkelsen T.
Moran J.V.
Mulder N.
Pollara V.J.
Ponting C.P.
Schuler G.
Schultz J.
Slater G.
Smit A.F.
Stupka E.
Szustakowski J.
Thierry-Mieg D.
Thierry-Mieg J.
Wagner L.
Wallis J.
Wheeler R.
Williams A.
Wolf Y.I.
Wolfe K.H.
Yang S.P.
Yeh R.F.
Collins F.
Guyer M.S.
Peterson J.
Felsenfeld A.
Wetterstrand K.A.
Patrinos A.
Morgan M.J.
de Jong P.
Catanese J.J.
Osoegawa K.
Shizuya H.
Choi S.
Chen Y.J.

Deloukas P.
Earthrowl M.E.
Grafham D.V.
Rubenfield M.
French L.
Steward C.A.
Sims S.K.
Jones M.C.
Searle S.
Scott C.
Howe K.
Hunt S.E.
Andrews T.D.
Gilbert J.G.
Swarbreck D.
Ashurst J.L.
Taylor A.
Battles J.
Bird C.P.
Ainscough R.
Almeida J.P.
Ashwell R.I.
Ambrose K.D.
Babbage A.K.
Bagguley C.L.
Bailey J.
Banerjee R.
Bates K.
Beasley H.
Bray-Allen S.
Brown A.J.
Brown J.Y.
Burford D.C.
Burrill W.
Burton J.
Cahill P.
Camire D.
Carter N.P.
Chapman J.C.
Clark S.Y.
Clarke G.
Clee C.M.
Clegg S.
Corby N.
Coulson A.
Dhami P.
Dutta I.
Dunn M.
Faulkner L.
Frankish A.
Frankland J.A.
Garner P.
Garnett J.
Gribble S.
Griffiths C.
Grocock R.
Gustafson E.
Hammond S.
Harley J.L.
Hart E.
Heath P.D.
Ho T.P.
Hopkins B.
Horne J.
Howden P.J.
Huckle E.
Hynds C.
Johnson C.
Johnson D.
Kana A.
Kay M.
Kimberley A.M.
Kershaw J.K.
Kokkinaki M.
Laird G.K.
Lawlor S.
Lee H.M.
Leongamornlert D.A.
Laird G.
Lloyd C.
Lloyd D.M.
Loveland J.
Lovell J.
McLaren S.
McLay K.E.
McMurray A.
Mashreghi-Mohammadi M.
Matthews L.
Milne S.
Nickerson T.
Nguyen M.
Overton-Larty E.
Palmer S.A.
Pearce A.V.
Peck A.I.
Pelan S.
Phillimore B.
Porter K.
Rice C.M.
Rogosin A.
Ross M.T.
Sarafidou T.
Sehra H.K.
Shownkeen R.
Skuce C.D.
Smith M.
Standring L.
Sycamore N.
Tester J.
Thorpe A.
Torcasso W.
Tracey A.
Tromans A.
Tsolas J.
Wall M.
Walsh J.
Wang H.
Weinstock K.
West A.P.
Willey D.L.
Whitehead S.L.
Wilming L.
Wray P.W.
Young L.
Chen Y.
Lovering R.C.
Moschonas N.K.
Siebert R.
Fechtel K.
Bentley D.
Durbin R.
Hubbard T.
Doucette-Stamm L.
Beck S.
Smith D.R.
Rogers J.

The DNA sequence and comparative analysis of human chromosome 10.

F:transmembrane receptor protein serine/threonine kinase activity

Receptor protein serine/threonine kinase


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Zygaenoidea Megalopygidae Megalopyge

Walker A.A.
Robinson S.D.
Merritt D.J.
Cardoso F.C.
Goudarzi M.H.
Mercedes R.S.
Eagles D.A.
Cooper P.
Zdenek C.N.
Fry B.G.
Hall D.W.
Vetter I.
King G.F.

Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae).

NUCLEOTIDE SEQUENCE [MRNA]
MASS SPECTROMETRY
SYNTHESIS OF 24-48
SUBCELLULAR LOCATION
TISSUE SPECIFICITY
DEVELOPMENTAL STAGE


Structure-specific endonuclease subunit SLX4

Helical

Helical

Helical

Helical

BTB

Disordered

Disordered

Disordered

Disordered

Disordered

Basic residues

Polar residues

Polar residues

P:resolution of meiotic recombination intermediates

STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Hadeninae Mythimna

Helical

Helical

Identification and sex expression profiles of olfactory-related genes in Mythimna loreyi based on antennal transcriptome analysis.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae Saxifragales Paeoniaceae Paeonia

Disordered

Disordered

Basic and acidic residues

Basic and acidic residues

TRANSCRIPTION FACTOR, PUTATIVE (DUF863)-RELATED


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus

Disordered

Church D.M.
Goodstadt L.
Hillier L.W.
Zody M.C.
Goldstein S.
She X.
Bult C.J.
Agarwala R.
Cherry J.L.
DiCuccio M.
Hlavina W.
Kapustin Y.
Meric P.
Maglott D.
Birtle Z.
Marques A.C.
Graves T.
Zhou S.
Teague B.
Potamousis K.
Churas C.
Place M.
Herschleb J.
Runnheim R.
Forrest D.
Amos-Landgraf J.
Schwartz D.C.
Cheng Z.
Lindblad-Toh K.
Eichler E.E.
Ponting C.P.

Lineage-specific biology revealed by a finished genome assembly of the mouse.

Church D.M.
Schneider V.A.
Graves T.
Auger K.
Cunningham F.
Bouk N.
Chen H.C.
Agarwala R.
McLaren W.M.
Ritchie G.R.
Albracht D.
Kremitzki M.
Rock S.
Kotkiewicz H.
Kremitzki C.
Wollam A.
Trani L.
Fulton L.
Fulton R.
Matthews L.
Whitehead S.
Chow W.
Torrance J.
Dunn M.
Harden G.
Threadgold G.
Wood J.
Collins J.
Heath P.
Griffiths G.
Pelan S.
Grafham D.
Eichler E.E.
Weinstock G.
Mardis E.R.
Wilson R.K.
Howe K.
Flicek P.
Hubbard T.

Modernizing reference genome assemblies.

Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility

Cytoplasm, cytoskeleton, flagellum axoneme


Viruses
Varidnaviria
Bamfordvirae
Preplasmiviricota
Tectiliviricetes
Rowavirales
Adenoviridae
Mastadenovirus
Mastadenovirus tarandri

Removed

Pre-histone-like nucleoprotein

Histone-like nucleoprotein

Disordered

Cleavage; by viral protease

Dastjerdi A.
Jeckel S.
Davies H.
Irving J.
Lounge C.
Plummer C.
Vidovszky M.Z.
Harrach B.
Chantrey J.
Williams J.

Novel adenovirus associated with necrotizing bronchiolitis in a captive reindeer (Rangifer tarandus).

Plays a role in the inhibition of host immune response within the nucleus. Interacts with cellular nucleosomes and immobilizes the host immune danger signal HMGB1 on chromatin. In turn, prevents HMGB1 release out of the cell and thus decreases inflammation. Plays also a role in the wrapping and condensation of the viral DNA. May also promote viral genome import into the nucleus

Interacts with the core-capsid bridging protein; this interaction bridges the virus core to the capsid. Interacts with host NPM1; this interaction might play a role in placing the pre-histone-like nucleoprotein on the viral DNA or regulating viral gene expression. Interacts with host HMGB1; this interaction inhibits host immune response

Located inside the capsid in association with the viral DNA (core). Present in about 1070 copies per virion

Expressed in the late phase of the viral replicative cycle

Cleaved near the N-terminus by the viral protease during virion maturation to form the mature protein

All late proteins expressed from the major late promoter are produced by alternative splicing and alternative polyadenylation of the same gene giving rise to non-overlapping ORFs. A leader sequence is present in the N-terminus of all these mRNAs and is recognized by the viral shutoff protein to provide expression although conventional translation via ribosome scanning from the cap has been shut off in the host cell

Belongs to the adenoviridae histone-like nucleoprotein family

Lacks conserved residue(s) required for the propagation of feature annotation


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Family with sequence similarity 136 member A

Disordered

Basic and acidic residues

Hillier L.W.
Graves T.A.
Fulton R.S.
Fulton L.A.
Pepin K.H.
Minx P.
Wagner-McPherson C.
Layman D.
Wylie K.
Sekhon M.
Becker M.C.
Fewell G.A.
Delehaunty K.D.
Miner T.L.
Nash W.E.
Kremitzki C.
Oddy L.
Du H.
Sun H.
Bradshaw-Cordum H.
Ali J.
Carter J.
Cordes M.
Harris A.
Isak A.
van Brunt A.
Nguyen C.
Du F.
Courtney L.
Kalicki J.
Ozersky P.
Abbott S.
Armstrong J.
Belter E.A.
Caruso L.
Cedroni M.
Cotton M.
Davidson T.
Desai A.
Elliott G.
Erb T.
Fronick C.
Gaige T.
Haakenson W.
Haglund K.
Holmes A.
Harkins R.
Kim K.
Kruchowski S.S.
Strong C.M.
Grewal N.
Goyea E.
Hou S.
Levy A.
Martinka S.
Mead K.
McLellan M.D.
Meyer R.
Randall-Maher J.
Tomlinson C.
Dauphin-Kohlberg S.
Kozlowicz-Reilly A.
Shah N.
Swearengen-Shahid S.
Snider J.
Strong J.T.
Thompson J.
Yoakum M.
Leonard S.
Pearman C.
Trani L.
Radionenko M.
Waligorski J.E.
Wang C.
Rock S.M.
Tin-Wollam A.M.
Maupin R.
Latreille P.
Wendl M.C.
Yang S.P.
Pohl C.
Wallis J.W.
Spieth J.
Bieri T.A.
Berkowicz N.
Nelson J.O.
Osborne J.
Ding L.
Meyer R.
Sabo A.
Shotland Y.
Sinha P.
Wohldmann P.E.
Cook L.L.
Hickenbotham M.T.
Eldred J.
Williams D.
Jones T.A.
She X.
Ciccarelli F.D.
Izaurralde E.
Taylor J.
Schmutz J.
Myers R.M.
Cox D.R.
Huang X.
McPherson J.D.
Mardis E.R.
Clifton S.W.
Warren W.C.
Chinwalla A.T.
Eddy S.R.
Marra M.A.
Ovcharenko I.
Furey T.S.
Miller W.
Eichler E.E.
Bork P.
Suyama M.
Torrents D.
Waterston R.H.
Wilson R.K.

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Detarioideae Saraceae Saraca

Transcriptome analysis of Saraca asoca.


NTR

Disordered

Pro residues


Odorant binding protein/PBP-general odorant binding protein

Helical

Pheromone/general odorant binding protein domain


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Ligated ion channel binding I - glutamate

Genome insights into chemosensory and detoxification machineries of broad mite, Polyphagotarsonemus latus (Tarsonemidae: Acari).


Metabotropic glutamate receptor-like protein

Helical

Helical

Helical

Helical

Helical

Helical

Helical

G-protein coupled receptors family 3 profile

Disordered

Disordered

Disordered

Polar residues

Low complexity

Polar residues

P:phospholipase C-activating G protein-coupled glutamate receptor signaling pathway

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors

Belongs to the G-protein coupled receptor 3 family


Helical


Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Polypodiopsida
Polypodiidae
Polypodiales
Pteridineae
Pteridaceae
Pteridoideae
Pteris
Pteris subgen. Campteria
Pteris sect. Excelsae

Helical

Helical

Helical

Helical

Helical

Helical

F:phosphate transmembrane transporter activity

Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family


axial binding residue

Selvamani S.B.
Negi N.
Nagarjuna Reddy K.V.
Ramasamy G.G.

Identification of Cytochrome P450s in Maconellicoccus hirsutus.

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Helical

Helical

Helical

Helical

Helical

Helical

Helical


Helical

Helical

Helical

Helical

Helical

Helical

Helical

Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Stenopodainae Oncocephalus

Zdenek C.N.
Cardoso F.C.
Robinson S.D.
Mercedes R.S.
Raidjoe E.R.
Hernandez-Vargas M.J.
Jin J.
Corzo G.
Vetter I.
King G.F.
Fry B.G.
Walker A.

Venom adaptation and exaptation during the trophic switch to blood-feeding by kissing bugs (Reduviidae: Triatominae).


P-loop containing nucleotide triphosphate hydrolases

P-loop containing nucleoside triphosphate hydrolases

Belongs to the small GTPase superfamily. Ras family


FZ


Paf1 complex subunit Cdc73 N-terminal

A novel Pathogenic CDC73 Gene Variant in Hyperparathyroidism Jaw Tumor Syndrome.


Glycoside hydrolase family 9

F:hydrolase activity, hydrolyzing O-glycosyl compounds

Belongs to the glycosyl hydrolase 9 (cellulase E) family


Helical

Helical

Helical

Helical

Helical

Helical

Lacks conserved residue(s) required for the propagation of feature annotation


Odorant binding protein/PBP-general odorant binding protein

Pheromone/general odorant binding protein domain


Disordered

Pro residues

Initial sequencing and analysis of the human genome.

Finishing the euchromatic sequence of the human genome.

Gregory S.G.
Barlow K.F.
McLay K.E.
Kaul R.
Swarbreck D.
Dunham A.
Scott C.E.
Howe K.L.
Woodfine K.
Spencer C.C.
Jones M.C.
Gillson C.
Searle S.
Zhou Y.
Kokocinski F.
McDonald L.
Evans R.
Phillips K.
Atkinson A.
Cooper R.
Jones C.
Hall R.E.
Andrews T.D.
Lloyd C.
Ainscough R.
Almeida J.P.
Ambrose K.D.
Anderson F.
Andrew R.W.
Ashwell R.I.
Aubin K.
Babbage A.K.
Bagguley C.L.
Bailey J.
Beasley H.
Bethel G.
Bird C.P.
Bray-Allen S.
Brown J.Y.
Brown A.J.
Buckley D.
Burton J.
Bye J.
Carder C.
Chapman J.C.
Clark S.Y.
Clarke G.
Clee C.
Cobley V.
Collier R.E.
Corby N.
Coville G.J.
Davies J.
Deadman R.
Dunn M.
Earthrowl M.
Ellington A.G.
Errington H.
Frankish A.
Frankland J.
French L.
Garner P.
Garnett J.
Gay L.
Ghori M.R.
Gibson R.
Gilby L.M.
Gillett W.
Glithero R.J.
Grafham D.V.
Griffiths C.
Griffiths-Jones S.
Grocock R.
Hammond S.
Harrison E.S.
Hart E.
Haugen E.
Heath P.D.
Holmes S.
Holt K.
Howden P.J.
Hunt A.R.
Hunt S.E.
Hunter G.
Isherwood J.
James R.
Johnson C.
Johnson D.
Joy A.
Kay M.
Kershaw J.K.
Kibukawa M.
Kimberley A.M.
King A.
Knights A.J.
Lad H.
Laird G.
Lawlor S.
Leongamornlert D.A.
Lloyd D.M.
Loveland J.
Lovell J.
Lush M.J.
Lyne R.
Martin S.
Mashreghi-Mohammadi M.
Matthews L.
Matthews N.S.
McLaren S.
Milne S.
Mistry S.
Moore M.J.
Nickerson T.
O'Dell C.N.
Oliver K.
Palmeiri A.
Palmer S.A.
Parker A.
Patel D.
Pearce A.V.
Peck A.I.
Pelan S.
Phelps K.
Phillimore B.J.
Plumb R.
Rajan J.
Raymond C.
Rouse G.
Saenphimmachak C.
Sehra H.K.
Sheridan E.
Shownkeen R.
Sims S.
Skuce C.D.
Smith M.
Steward C.
Subramanian S.
Sycamore N.
Tracey A.
Tromans A.
Van Helmond Z.
Wall M.
Wallis J.M.
White S.
Whitehead S.L.
Wilkinson J.E.
Willey D.L.
Williams H.
Wilming L.
Wray P.W.
Wu Z.
Coulson A.
Vaudin M.
Sulston J.E.
Durbin R.
Hubbard T.
Wooster R.
Dunham I.
Carter N.P.
McVean G.
Ross M.T.
Harrow J.
Olson M.V.
Beck S.
Rogers J.
Bentley D.R.
Banerjee R.
Bryant S.P.
Burford D.C.
Burrill W.D.
Clegg S.M.
Dhami P.
Dovey O.
Faulkner L.M.
Gribble S.M.
Langford C.F.
Pandian R.D.
Porter K.M.
Prigmore E.

The DNA sequence and biological annotation of human chromosome 1.


Disordered

Disordered

Basic and acidic residues

Acidic residues

Polar residues


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Rosales Elaeagnaceae Hippophae

K-box

Zhao J.
Xu Y.
Zhang Z.
Zhao M.
Li K.
Wang F.
Sun K.

Genome-wide analysis of the MADS-box gene family of sea buckthorn (Hippophae rhamnoides ssp. sinensis) and their potential role in floral organ development.

F:DNA-binding transcription factor activity


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Polychaeta Errantia Eunicida Dorvilleidae Ophryotrocha

Helical

VWFD

Filamin

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

EGF-like

SEA

EGF-like

D or N

Latent-transforming growth factor beta-binding protein 3


Helical

Helical

Helical

Disordered

Polar residues

Crucial to convey clamshell closure to channel opening

Interaction with the cone snail toxin Con-ikot-ikot

F:transmitter-gated monoatomic ion channel activity

P:cell surface receptor signaling pathway

Eye-enriched kainate receptor, isoform B

Glutamate receptor ionotropic, kainate 1

Glutamate receptor ionotropic, kainate 2

Putative glutamate receptor ionotropic kainate 1

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family


Peptidase S1


Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Myrtales
Myrtaceae
Myrtoideae
Myrteae
Pimenta group
Psidium

Terpene synthase N-terminal

Canal D.
dos Santos P.H.D.
Carpinetti-Oliveira P.A.
Silva M.A.
Fernandes M.
Brustolini O.J.B.
Ferreira A.
Ferreira M.F.S.

Comparative genome-wide analysis of two guava cultivars revels plasticity of sesquiterpene biosynthesis.


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca

Ig-like

Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase


Helical


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Peiratinae Ectomocoris

Peptidase S1

Belongs to the peptidase S1 family. CLIP subfamily


Proprotein convertase subtilisin/kexin type 9

Inhibitor I9

Peptidase S8/S53

Peptidase S8 propeptide/proteinase inhibitor I9

PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 9

Lacks conserved residue(s) required for the propagation of feature annotation


Disordered

Acidic residues

Polar residues


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Bivalvia Autobranchia Pteriomorphia Pterioida Pterioidea Pteriidae Pinctada

DED


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Pentatomomorpha Pentatomoidea Pentatomidae Asopinae Arma

Helical

TIR

Disordered

Polar residues

miR-8 maintains the immune homeostasis of Arma chinensis Fallou by inhibiting AcMNPV's essential genes and regulating the innate immune response in host insect.

F:transmembrane signaling receptor activity

Toll/interleukin-1 receptor homology (TIR) domain

Belongs to the Toll-like receptor family


Deleted in malignant brain tumors 1 protein-like protein 2

SRCR

SRCR

SRCR

Ig-like

Ig-like

Protein kinase

Ig-like

DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED


RNase L inhibitor RLI-like possible metal-binding

Disordered

F:rRNA small subunit aminocarboxypropyltransferase activity

RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes


Helical

axial binding residue

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Ranunculales Papaveraceae Fumarioideae Corydalis

Helical

axial binding residue

P:isoquinoline alkaloid biosynthetic process


Reverse transcriptase domain-containing protein

Disordered

Disordered

Disordered

Disordered

Disordered

Basic and acidic residues

Polar residues

Polar residues

Basic and acidic residues

Low complexity

REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN

REVERSE TRANSCRIPTASE-LIKE PROTEIN WITH RNA-DIRECTED DNA POLYMERASE DOMAIN


Helical

Helical

Helical

Helical

F:extracellularly glutamate-gated chloride channel activity

glutamate-gated chloride channel isoform X1

Neurotransmitter-gated ion-channel ligand-binding domain

Neurotransmitter-gated ion-channel transmembrane domain

Neurotransmitter-gated ion-channel transmembrane pore

Nicotinic receptor ligand binding domain-like

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glutamate-gated chloride channel (TC 1.A.9.4) subfamily


Nusbaum C.
Zody M.C.
Borowsky M.L.
Kamal M.
Kodira C.D.
Taylor T.D.
Whittaker C.A.
Chang J.L.
Cuomo C.A.
Dewar K.
FitzGerald M.G.
Yang X.
Abouelleil A.
Allen N.R.
Anderson S.
Bloom T.
Bugalter B.
Butler J.
Cook A.
DeCaprio D.
Engels R.
Garber M.
Gnirke A.
Hafez N.
Hall J.L.
Norman C.H.
Itoh T.
Jaffe D.B.
Kuroki Y.
Lehoczky J.
Lui A.
Macdonald P.
Mauceli E.
Mikkelsen T.S.
Naylor J.W.
Nicol R.
Nguyen C.
Noguchi H.
O'Leary S.B.
O'Neill K.
Piqani B.
Smith C.L.
Talamas J.A.
Topham K.
Totoki Y.
Toyoda A.
Wain H.M.
Young S.K.
Zeng Q.
Zimmer A.R.
Fujiyama A.
Hattori M.
Birren B.W.
Sakaki Y.
Lander E.S.

DNA sequence and analysis of human chromosome 18.


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus

IgG Fc fragment receptor transporter alpha chain

IgG receptor FcRn large subunit p51

Ig-like

Disordered

Low complexity

Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles.

Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation. In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB

FcRn complex consists of two subunits: p51, and p14 which is equivalent to beta-2-microglobulin. It forms an MHC class I-like heterodimer. Interacts with albumin/ALB; this interaction regulates ALB homeostasis

Belongs to the immunoglobulin superfamily


Epithelial sodium channel/degenerin-like protein

Helical

Disordered

Polar residues

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Pentatomomorpha Pentatomoidea Pentatomidae Asopinae Eocanthecona

Pheromone/general odorant binding protein domain


Disordered

Basic residues

P-loop containing nucleotide triphosphate hydrolases

RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY

P-loop containing nucleoside triphosphate hydrolases


Helical

Helical

Helical

Pathak J.
Thiruvengadam V.
Gracy G.R.
M M.


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Clitellata Oligochaeta Enchytraeida Enchytraeidae Enchytraeus

RRM

Disordered

Polar residues

Kostyuchenko R.P.
Nikanorova D.D.
Amosov A.V.

Germ Line/Multipotency Genes Show Differential Expression during Embryonic Development of the Annelid Enchytraeus coronatus.

P:positive regulation of translational initiation


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Diptera Brachycera Muscomorpha Oestroidea Sarcophagidae Sarcophaga Pandelleisca

Expression of genes involved in ecdysteroidogenesis in relation to pupal diapause entry in the flesh fly Sarcophaga similis.


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Zygaenoidea Limacodidae Comana

Goudarzi M.H.
Robinson S.D.
Cardoso F.C.
Mitchell M.L.
Cook L.G.
King G.F.
Walker A.A.

Phylogeny, envenomation syndrome, and membrane-permeabilising venom produced by Australia's 'electric' caterpillar Comana monomorpha (Lepidoptera: Limacodidae).


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Helical


Eukaryota Metazoa Spiralia Lophotrochozoa Phoronida Phoronidae Phoronis

BHLH

PAS

PAS

Disordered

Disordered

Disordered

Disordered

Low complexity

Polar residues

Low complexity

Belato F.A.
Mello B.
Coates C.J.
Halanych K.M.
Brown F.D.
Morandini A.C.
Leme J.M.
Trindade R.I.F.
Costa-Paiva E.M.

Divergence time estimates for the hypoxia-inducible factor-1 alpha (HIF1a) reveal an ancient emergence of animals in low-oxygen environments.

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1 subunit alpha

Hypoxia-inducible factor 1-alpha isoform 1

HLH, helix-loop-helix DNA-binding domain


SCP


Odorant binding protein/PBP-general odorant binding protein


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Polychaeta Sedentaria Canalipalpata Sabellida Siboglinidae Ridgeia

Helical

Ig-like

Disordered

Disordered

Polar residues

Perez M.
Aroh O.
Sun Y.
Lan Y.
Juniper S.K.
Young C.R.
Angers B.
Qian P.Y.

Third-Generation Sequencing Reveals the Adaptive Role of the Epigenome in Three Deep-Sea Polychaetes.

CARTILAGE INTERMEDIATE LAYER PROTEIN 1-LIKE ISOFORM X1

CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae Saxifragales Paeoniaceae Paeonia

Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase

F:shikimate 3-dehydrogenase (NADP+) activity

BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC


Adhesion G protein-coupled receptor L3-like protein

Helical

Helical

Helical

Helical

Helical

Helical

Helical

Disordered

Disordered

Disordered

Polar residues

Polar residues

Basic and acidic residues

Polar residues

Rhodopsin 7-helix transmembrane proteins

Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily


Peptidase S1


Fork-head

Fork-head

Disordered

Polar residues

F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain


Helical

Helical

Helical

Helical

Helical

Helical

Genome insights into chemosensory and detoxification machineries of broad mite, Polyphagotarsonemus latus (Tarsonemidae: Acari).

P:adenylate cyclase-activating adrenergic receptor signaling pathway

ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR

Family A G protein-coupled receptor-like

Belongs to the G-protein coupled receptor 1 family


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Hadeninae Mythimna

Identification and sex expression profiles of olfactory-related genes in Mythimna loreyi based on antennal transcriptome analysis.

Pheromone/general odorant binding protein domain


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Ostariophysi Characiformes Characoidei Acestrorhamphidae Acestrorhamphinae Astyanax

Nuclear receptor

Molecular and hormonal mechanisms underlying oocyte maturation and ovulation and its application to seed production in the lambari (Astyanax altiparanae).

F:DNA-binding transcription factor activity

Erythroid Transcription Factor GATA-1, subunit A

Glucocorticoid receptor-like (DNA-binding domain)


Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding

Augustine N.
Selvapandian U.
Muthugoundar M.

Evaluation of reference genes for expression studies in the broad mite, Polyphagotarsonemus latus (Acari: Tarsonemidae).

F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family


Disordered

Lineage-specific biology revealed by a finished genome assembly of the mouse.

Modernizing reference genome assemblies.

F:rRNA small subunit aminocarboxypropyltransferase activity

RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG


Belongs to the UDP-glycosyltransferase family


Disordered

Basic and acidic residues

Lander E.S.
Linton L.M.
Birren B.
Nusbaum C.
Zody M.C.
Baldwin J.
Devon K.
Dewar K.
Doyle M.
FitzHugh W.
Funke R.
Gage D.
Harris K.
Heaford A.
Howland J.
Kann L.
Lehoczky J.
LeVine R.
McEwan P.
McKernan K.
Meldrim J.
Mesirov J.P.
Miranda C.
Morris W.
Naylor J.
Raymond C.
Rosetti M.
Santos R.
Sheridan A.
Sougnez C.
Stange-Thomann N.
Stojanovic N.
Subramanian A.
Wyman D.
Rogers J.
Sulston J.
Ainscough R.
Beck S.
Bentley D.
Burton J.
Clee C.
Carter N.
Coulson A.
Deadman R.
Deloukas P.
Dunham A.
Dunham I.
Durbin R.
French L.
Grafham D.
Gregory S.
Hubbard T.
Humphray S.
Hunt A.
Jones M.
Lloyd C.
McMurray A.
Matthews L.
Mercer S.
Milne S.
Mullikin J.C.
Mungall A.
Plumb R.
Ross M.
Shownkeen R.
Sims S.
Waterston R.H.
Wilson R.K.
Hillier L.W.
McPherson J.D.
Marra M.A.
Mardis E.R.
Fulton L.A.
Chinwalla A.T.
Pepin K.H.
Gish W.R.
Chissoe S.L.
Wendl M.C.
Delehaunty K.D.
Miner T.L.
Delehaunty A.
Kramer J.B.
Cook L.L.
Fulton R.S.
Johnson D.L.
Minx P.J.
Clifton S.W.
Hawkins T.
Branscomb E.
Predki P.
Richardson P.
Wenning S.
Slezak T.
Doggett N.
Cheng J.F.
Olsen A.
Lucas S.
Elkin C.
Uberbacher E.
Frazier M.
Gibbs R.A.
Muzny D.M.
Scherer S.E.
Bouck J.B.
Sodergren E.J.
Worley K.C.
Rives C.M.
Gorrell J.H.
Metzker M.L.
Naylor S.L.
Kucherlapati R.S.
Nelson D.L.
Weinstock G.M.
Sakaki Y.
Fujiyama A.
Hattori M.
Yada T.
Toyoda A.
Itoh T.
Kawagoe C.
Watanabe H.
Totoki Y.
Taylor T.
Weissenbach J.
Heilig R.
Saurin W.
Artiguenave F.
Brottier P.
Bruls T.
Pelletier E.
Robert C.
Wincker P.
Smith D.R.
Doucette-Stamm L.
Rubenfield M.
Weinstock K.
Lee H.M.
Dubois J.
Rosenthal A.
Platzer M.
Nyakatura G.
Taudien S.
Rump A.
Yang H.
Yu J.
Wang J.
Huang G.
Gu J.
Hood L.
Rowen L.
Madan A.
Qin S.
Davis R.W.
Federspiel N.A.
Abola A.P.
Proctor M.J.
Myers R.M.
Schmutz J.
Dickson M.
Grimwood J.
Cox D.R.
Olson M.V.
Kaul R.
Raymond C.
Shimizu N.
Kawasaki K.
Minoshima S.
Evans G.A.
Athanasiou M.
Schultz R.
Roe B.A.
Chen F.
Pan H.
Ramser J.
Lehrach H.
Reinhardt R.
McCombie W.R.
de la Bastide M.
Dedhia N.
Blocker H.
Hornischer K.
Nordsiek G.
Agarwala R.
Aravind L.
Bailey J.A.
Bateman A.
Batzoglou S.
Birney E.
Bork P.
Brown D.G.
Burge C.B.
Cerutti L.
Chen H.C.
Church D.
Clamp M.
Copley R.R.
Doerks T.
Eddy S.R.
Eichler E.E.
Furey T.S.
Galagan J.
Gilbert J.G.
Harmon C.
Hayashizaki Y.
Haussler D.
Hermjakob H.
Hokamp K.
Jang W.
Johnson L.S.
Jones T.A.
Kasif S.
Kaspryzk A.
Kennedy S.
Kent W.J.
Kitts P.
Koonin E.V.
Korf I.
Kulp D.
Lancet D.
Lowe T.M.
McLysaght A.
Mikkelsen T.
Moran J.V.
Mulder N.
Pollara V.J.
Ponting C.P.
Schuler G.
Schultz J.
Slater G.
Smit A.F.
Stupka E.
Szustakowski J.
Thierry-Mieg D.
Thierry-Mieg J.
Wagner L.
Wallis J.
Wheeler R.
Williams A.
Wolf Y.I.
Wolfe K.H.
Yang S.P.
Yeh R.F.
Collins F.
Guyer M.S.
Peterson J.
Felsenfeld A.
Wetterstrand K.A.
Patrinos A.
Morgan M.J.
de Jong P.
Catanese J.J.
Osoegawa K.
Shizuya H.
Choi S.
Chen Y.J.

Initial sequencing and analysis of the human genome.

Finishing the euchromatic sequence of the human genome.

Cole C.G.
McCann O.T.
Collins J.E.
Oliver K.
Willey D.
Gribble S.M.
Yang F.
McLaren K.
Rogers J.
Ning Z.
Beare D.M.
Dunham I.

Finishing the finished human chromosome 22 sequence.


Bacteria Pseudomonadati Pseudomonadota Alphaproteobacteria Rickettsiales Lyticum

Lon N-terminal

Lon proteolytic

Castelli M.
Nardi T.
Gammuto L.
Bellinzona G.
Sabaneyeva E.
Potekhin A.
Serra V.
Petroni G.
Sassera D.

Host association and intracellularity evolved multiple times independently in the Rickettsiales.

P:protein quality control for misfolded or incompletely synthesized proteins

P-loop containing nucleotide triphosphate hydrolases

P-loop containing nucleoside triphosphate hydrolases

ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner

Hydrolysis of proteins in presence of ATP.

Homohexamer. Organized in a ring with a central cavity

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus

axial binding residue

Identification of Cytochrome P450s in Maconellicoccus hirsutus.

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Heteroptera Panheteroptera Cimicomorpha Reduviidae Stenopodainae Oncocephalus

Venom adaptation and exaptation during the trophic switch to blood-feeding by kissing bugs (Reduviidae: Triatominae).


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Aplacophora Solenogastres Cavibelonia Amphimeniidae Alexandromenia

PAS

Disordered

Disordered

Disordered

Basic and acidic residues

Basic and acidic residues

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca

Disordered

Polar residues

Polar residues


Disordered

Low complexity

Low complexity


F-box

PDZ


Muscrinic acethylcholine receptor-like GPCR protein

Helical

Helical

Helical

Helical

Helical

Helical

Disordered

Disordered

Disordered

Disordered

Low complexity

Low complexity

Polar residues

Polar residues

Basic and acidic residues

Polar residues

Basic and acidic residues

F:G protein-coupled acetylcholine receptor activity

F:G protein-coupled serotonin receptor activity

P:adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Rhodopsin 7-helix transmembrane proteins

MUSCARINIC ACETYLCHOLINE RECEPTOR, B-TYPE, ISOFORM A

Family A G protein-coupled receptor-like

Belongs to the G-protein coupled receptor 1 family


Centromere-associated protein E-like protein

Kinesin motor

Disordered

Disordered

Disordered

Disordered

Disordered

Disordered

Acidic residues

Basic and acidic residues

Basic and acidic residues

Polar residues

P-loop containing nucleoside triphosphate hydrolases

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family


Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Pinopsida
Pinidae
Conifers I
Pinales
Pinaceae
Pinus
Pinus subgen. Pinus

PAZ

RNase III

RNase III

DRBM

Identification of RNAi-Related Genes and Transcriptome Assembly of Loblolly Pine (Pinus taeda, L.) Seedlings Exposed to Insect-Specific dsRNA.


Metalloendopeptidase

Peptidase M12A

DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING

Metalloproteases ('zincins'), catalytic domain

Lacks conserved residue(s) required for the propagation of feature annotation


Eukaryota Metazoa Spiralia Lophotrochozoa Brachiopoda Rhynchonelliformea Rhynchonellata Terebratellidina Laqueoidea Laqueidae Terebratalia

FZ

NTR

Disordered

Basic residues

Vellutini B.C.
Martin-Duran J.M.
Borve A.
Hejnol A.

Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning.

Belongs to the secreted frizzled-related protein (sFRP) family


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Aplacophora Solenogastres Pholidoskepia Macellomeniidae Macellomenia

BHLH

PAS

PAS

Disordered

Disordered

Basic residues

Basic and acidic residues

Polar residues

Low complexity

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1-alpha isoform 1


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Asparagales Asparagaceae Agavoideae Agave

SBP-type

Disordered

Basic residues

Hernandez-Soriano L.
Galvez-Sandre L.
Avila De Dios E.
Simpson J.

How to awaken a sleeping giant: antagonistic expression of flowering locus T homologs and elements of the age related pathway are associated with the flowering transition in Agave tequilana.

SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 4

SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 7


Eukaryota
Viridiplantae
Chlorophyta
core chlorophytes
Chlorophyceae
CS clade
Chlamydomonadales
Dunaliellaceae
Dunaliella

Helical

Malic enzyme N-terminal

Proton donor

Proton acceptor

Combined Effects of Nitrogen Limitation and Overexpression of Malic Enzyme Gene on Lipid Accumulation in Dunaliella parva.

F:malate dehydrogenase (decarboxylating) (NADP+) activity

Aminoacid dehydrogenase-like, N-terminal domain

Divalent metal cations. Prefers magnesium or manganese.


Cystatin

F:cysteine-type endopeptidase inhibitor activity


Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Vibrionales Vibrionaceae Vibrio

Gruschow S.
McQuarrie S.
Ackermann K.
McMahon S.
Bode B.E.
Gloster T.M.
White M.F.

CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23.


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

Disordered

Disordered

Basic and acidic residues

Zody M.C.
Garber M.
Sharpe T.
Young S.K.
Rowen L.
O'Neill K.
Whittaker C.A.
Kamal M.
Chang J.L.
Cuomo C.A.
Dewar K.
FitzGerald M.G.
Kodira C.D.
Madan A.
Qin S.
Yang X.
Abbasi N.
Abouelleil A.
Arachchi H.M.
Baradarani L.
Birditt B.
Bloom S.
Bloom T.
Borowsky M.L.
Burke J.
Butler J.
Cook A.
DeArellano K.
DeCaprio D.
Dorris L.III.
Dors M.
Eichler E.E.
Engels R.
Fahey J.
Fleetwood P.
Friedman C.
Gearin G.
Hall J.L.
Hensley G.
Johnson E.
Jones C.
Kamat A.
Kaur A.
Locke D.P.
Madan A.
Munson G.
Jaffe D.B.
Lui A.
Macdonald P.
Mauceli E.
Naylor J.W.
Nesbitt R.
Nicol R.
O'Leary S.B.
Ratcliffe A.
Rounsley S.
She X.
Sneddon K.M.
Stewart S.
Sougnez C.
Stone S.M.
Topham K.
Vincent D.
Wang S.
Zimmer A.R.
Birren B.W.
Hood L.
Lander E.S.
Nusbaum C.

Analysis of the DNA sequence and duplication history of human chromosome 15.


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Aplacophora Solenogastres Pholidoskepia Dondersiidae Helluoherpia

BHLH

PAS

PAS

Disordered

Disordered

Disordered

Disordered

Disordered

Basic residues

Basic and acidic residues

Basic and acidic residues

Low complexity

Polar residues

Divergence time estimates for the hypoxia-inducible factor-1 alpha (HIF1a) reveal an ancient emergence of animals in low-oxygen environments.

HLH, helix-loop-helix DNA-binding domain


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Helical

Glycosyl transferase family 28 C-terminal

Genome insights into chemosensory and detoxification machineries of broad mite, Polyphagotarsonemus latus (Tarsonemidae: Acari).

Belongs to the UDP-glycosyltransferase family


Disordered

Disordered

COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Bivalvia Autobranchia Pteriomorphia Pterioida Pterioidea Pteriidae Pinctada

Integrase catalytic

ShKT

BPTI/Kunitz inhibitor

Disordered

Disordered

Disordered

Polar residues

Low complexity

Polar residues

The improved chromosome-level genome for the pearl oyster Pinctada fucata martensii using PacBio sequencing and Hi-C.

F:serine-type endopeptidase inhibitor activity

Retrovirus-related Pol polyprotein from transposon 297-like Protein

Retrovirus-related Pol polyprotein from transposon gypsy-like Protein

Pancreatic trypsin inhibitor Kunitz domain

Ribonuclease H-like superfamily/Ribonuclease H

ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED

Retrovirus capsid dimerization domain-like

Lacks conserved residue(s) required for the propagation of feature annotation

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Clitellata Hirudinea Hirudinida Hirudiniformes Hirudinidae Hirudo


Antistasin-like

Belongs to the protease inhibitor I15 (antistasin) family


Eukaryota Sar Alveolata Apicomplexa Aconoidasida Piroplasmida Theileriidae Theileria

Lu X.
Wang S.
Chen L.
Liu M.
Liu Y.
Zhu H.
Jiang B.
Du S.
Bayin C.
Liu D.
Zhang W.

Cloning and prokaryotic expression of Theileria equi rhoptry neck protein 5 gene.

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus

S S.B.
Negi N.
Nagarjuna Reddy K.
R G.G.

Takout-proteins of Maconellicoccus hirsutus.

Haemolymph juvenile hormone binding protein


Helical

Helical

Ionotropic glutamate receptor L-glutamate and glycine-binding

Ionotropic glutamate receptor C-terminal

F:ligand-gated monoatomic ion channel activity

P:detection of stimulus involved in sensory perception

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family

Belongs to the vasopressin/oxytocin family


Eukaryota Metazoa Ecdysozoa Arthropoda Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Caridea Palaemonoidea Palaemonidae Macrobrachium

USP

Disordered

Disordered

Disordered

Disordered

Disordered

Low complexity

Polar residues

Low complexity

Basic and acidic residues

Polar residues

Basic and acidic residues

Basic and acidic residues

Acidic residues

Low complexity

Polar residues

Polar residues

Basic and acidic residues

Low complexity

UBIQUITIN CARBOXYL-TERMINAL HYDROLASE USP2

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).


Eukaryota Metazoa Hemichordata Enteropneusta Harrimaniidae

BHLH

PAS

PAS

Disordered

Basic and acidic residues

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II transcription regulatory region sequence-specific DNA binding

Hypoxia-inducible factor 1 subunit alpha

Hypoxia-inducible factor 1-alpha isoform 1

hypoxia-inducible factor 3-alpha isoform X1

HLH, helix-loop-helix DNA-binding domain


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Zygaenoidea Limacodidae Comana

Phylogeny, envenomation syndrome, and membrane-permeabilising venom produced by Australia's 'electric' caterpillar Comana monomorpha (Lepidoptera: Limacodidae).

Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3

EJACULATORY BULB-SPECIFIC PROTEIN 3-RELATED


Initial sequencing and analysis of the human genome.

Mungall A.J.
Palmer S.A.
Sims S.K.
Edwards C.A.
Ashurst J.L.
Wilming L.
Jones M.C.
Horton R.
Hunt S.E.
Scott C.E.
Gilbert J.G.
Clamp M.E.
Bethel G.
Milne S.
Ainscough R.
Almeida J.P.
Ambrose K.D.
Andrews T.D.
Ashwell R.I.
Babbage A.K.
Bagguley C.L.
Bailey J.
Banerjee R.
Barker D.J.
Barlow K.F.
Bates K.
Beare D.M.
Beasley H.
Beasley O.
Bird C.P.
Blakey S.
Bray-Allen S.
Brook J.
Brown A.J.
Brown J.Y.
Burford D.C.
Burrill W.
Burton J.
Carder C.
Carter N.P.
Chapman J.C.
Clark S.Y.
Clark G.
Clee C.M.
Clegg S.
Cobley V.
Collier R.E.
Collins J.E.
Colman L.K.
Corby N.R.
Coville G.J.
Culley K.M.
Dhami P.
Davies J.
Dunn M.
Earthrowl M.E.
Ellington A.E.
Evans K.A.
Faulkner L.
Francis M.D.
Frankish A.
Frankland J.
French L.
Garner P.
Garnett J.
Ghori M.J.
Gilby L.M.
Gillson C.J.
Glithero R.J.
Grafham D.V.
Grant M.
Gribble S.
Griffiths C.
Griffiths M.
Hall R.
Halls K.S.
Hammond S.
Harley J.L.
Hart E.A.
Heath P.D.
Heathcott R.
Holmes S.J.
Howden P.J.
Howe K.L.
Howell G.R.
Huckle E.
Humphray S.J.
Humphries M.D.
Hunt A.R.
Johnson C.M.
Joy A.A.
Kay M.
Keenan S.J.
Kimberley A.M.
King A.
Laird G.K.
Langford C.
Lawlor S.
Leongamornlert D.A.
Leversha M.
Lloyd C.R.
Lloyd D.M.
Loveland J.E.
Lovell J.
Martin S.
Mashreghi-Mohammadi M.
Maslen G.L.
Matthews L.
McCann O.T.
McLaren S.J.
McLay K.
McMurray A.
Moore M.J.
Mullikin J.C.
Niblett D.
Nickerson T.
Novik K.L.
Oliver K.
Overton-Larty E.K.
Parker A.
Patel R.
Pearce A.V.
Peck A.I.
Phillimore B.
Phillips S.
Plumb R.W.
Porter K.M.
Ramsey Y.
Ranby S.A.
Rice C.M.
Ross M.T.
Searle S.M.
Sehra H.K.
Sheridan E.
Skuce C.D.
Smith S.
Smith M.
Spraggon L.
Squares S.L.
Steward C.A.
Sycamore N.
Tamlyn-Hall G.
Tester J.
Theaker A.J.
Thomas D.W.
Thorpe A.
Tracey A.
Tromans A.
Tubby B.
Wall M.
Wallis J.M.
West A.P.
White S.S.
Whitehead S.L.
Whittaker H.
Wild A.
Willey D.J.
Wilmer T.E.
Wood J.M.
Wray P.W.
Wyatt J.C.
Young L.
Younger R.M.
Bentley D.R.
Coulson A.
Durbin R.
Hubbard T.
Sulston J.E.
Dunham I.
Rogers J.
Beck S.

The DNA sequence and analysis of human chromosome 6.

Finishing the euchromatic sequence of the human genome.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Gentianales Apocynaceae Asclepiadoideae Marsdenieae Gymnema

EF-hand

EF-hand

EF-hand

Disordered

Polar residues

Low complexity

Low complexity

Transcriptomic revealing of plant pathogen interaction in Gymnema sylvestre.


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Eupercaria Spariformes Sparidae Acanthopagrus

Regulatory effects of dietary lipid levels on growth performance, lipid metabolism, ERS and inflammatory response of juvenile black seabream Acanthopagrus schlegelii under low-salinity environment.


Helical

Helical

Helical

Helical

Helical

Helical

Helical

Rhodopsin 7-helix transmembrane proteins

Family A G protein-coupled receptor-like

Belongs to the G-protein coupled receptor 1 family


Eukaryota Metazoa Porifera Demospongiae Heteroscleromorpha Poecilosclerida Latrunculiidae Latrunculia

PAS

Disordered

Disordered

Low complexity

Low complexity

Low complexity

Polar residues

Pro residues

Polar residues


Helical

Helical

Helical

Helical

glutamate receptor ionotropic, NMDA 1 isoform X1

Putative glutamate receptor ionotropic NMDA 2B


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Ostariophysi Cypriniformes Danionidae Danioninae Danio

Howe K.
Clark M.D.
Torroja C.F.
Torrance J.
Berthelot C.
Muffato M.
Collins J.E.
Humphray S.
McLaren K.
Matthews L.
McLaren S.
Sealy I.
Caccamo M.
Churcher C.
Scott C.
Barrett J.C.
Koch R.
Rauch G.J.
White S.
Chow W.
Kilian B.
Quintais L.T.
Guerra-Assuncao J.A.
Zhou Y.
Gu Y.
Yen J.
Vogel J.H.
Eyre T.
Redmond S.
Banerjee R.
Chi J.
Fu B.
Langley E.
Maguire S.F.
Laird G.K.
Lloyd D.
Kenyon E.
Donaldson S.
Sehra H.
Almeida-King J.
Loveland J.
Trevanion S.
Jones M.
Quail M.
Willey D.
Hunt A.
Burton J.
Sims S.
McLay K.
Plumb B.
Davis J.
Clee C.
Oliver K.
Clark R.
Riddle C.
Elliot D.
Eliott D.
Threadgold G.
Harden G.
Ware D.
Begum S.
Mortimore B.
Mortimer B.
Kerry G.
Heath P.
Phillimore B.
Tracey A.
Corby N.
Dunn M.
Johnson C.
Wood J.
Clark S.
Pelan S.
Griffiths G.
Smith M.
Glithero R.
Howden P.
Barker N.
Lloyd C.
Stevens C.
Harley J.
Holt K.
Panagiotidis G.
Lovell J.
Beasley H.
Henderson C.
Gordon D.
Auger K.
Wright D.
Collins J.
Raisen C.
Dyer L.
Leung K.
Robertson L.
Ambridge K.
Leongamornlert D.
McGuire S.
Gilderthorp R.
Griffiths C.
Manthravadi D.
Nichol S.
Barker G.
Whitehead S.
Kay M.
Brown J.
Murnane C.
Gray E.
Humphries M.
Sycamore N.
Barker D.
Saunders D.
Wallis J.
Babbage A.
Hammond S.
Mashreghi-Mohammadi M.
Barr L.
Martin S.
Wray P.
Ellington A.
Matthews N.
Ellwood M.
Woodmansey R.
Clark G.
Cooper J.
Cooper J.
Tromans A.
Grafham D.
Skuce C.
Pandian R.
Andrews R.
Harrison E.
Kimberley A.
Garnett J.
Fosker N.
Hall R.
Garner P.
Kelly D.
Bird C.
Palmer S.
Gehring I.
Berger A.
Dooley C.M.
Ersan-Urun Z.
Eser C.
Geiger H.
Geisler M.
Karotki L.
Kirn A.
Konantz J.
Konantz M.
Oberlander M.
Rudolph-Geiger S.
Teucke M.
Lanz C.
Raddatz G.
Osoegawa K.
Zhu B.
Rapp A.
Widaa S.
Langford C.
Yang F.
Schuster S.C.
Carter N.P.
Harrow J.
Ning Z.
Herrero J.
Searle S.M.
Enright A.
Geisler R.
Plasterk R.H.
Lee C.
Westerfield M.
de Jong P.J.
Zon L.I.
Postlethwait J.H.
Nusslein-Volhard C.
Hubbard T.J.
Roest Crollius H.
Rogers J.
Stemple D.L.

The zebrafish reference genome sequence and its relationship to the human genome.


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Buccinoidea Buccinidae Colubraria

VWFA

VWFA

Modica M.V.
Gerdol M.
Fracarossi D.
Cervelli M.
Reinoso Sanchez J.F.
Leone S.
Tartaglia G.
Milanetti E.
Vassalli Q.A.
Ruggeri Z.M.
Oliverio M.

A vampire's tale: a novel family of anti-platelet proteins from the marine snail Cumia reticulata.

VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 1


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos

Helical

Galectin

Galectin

Rosen B.D.
Bickhart D.M.
Koren S.
Schnabel R.D.
Hall R.
Zimin A.
Dreischer C.
Schultheiss S.
Schroeder S.G.
Elsik C.G.
Couldrey C.
Liu G.E.
Van Tassell C.P.
Phillippy A.M.
Smith T.P.L.
Medrano J.F.

ARS-UCD1.2.

Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions


Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Bivalvia Autobranchia Heteroconchia Palaeoheterodonta Unionida Unionoidea Unionidae Unioninae Sinanodonta

Helical

Apoptosis regulator Bcl-2 family BH4

Molecular identification and functional characterization of a novel Bcl-2 from Anodonta woodiana in response to cadmium exposure and Aeromonas hydrophila infection.

P:extrinsic apoptotic signaling pathway in absence of ligand

P:intrinsic apoptotic signaling pathway in response to DNA damage

P:release of cytochrome c from mitochondria

Bcl-2 inhibitors of programmed cell death


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo


Disordered

Low complexity


Goudarzi M.H.
Robinson S.D.
Cardoso F.C.
Mitchell M.L.
Cook L.G.
King G.F.
Walker A.A.


Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
eudicotyledons
Gunneridae
Pentapetalae
rosids
fabids
Fabales
Fabaceae
Papilionoideae
50 kb inversion clade
NPAAA clade
Hologalegina
IRL clade
Trifolieae
Medicago

Myb-like

Disordered

Disordered

Disordered

Polar residues

Polar residues

MYB_SANT-LIKE DNA-BINDING DOMAIN PROTEIN


Eukaryota Metazoa Cnidaria Scyphozoa Semaeostomeae Ulmaridae Aurelia

Tetraradial symmetry disturbance and recovery at feeding-dependent tentacle initiations in Aurelia aurita polyps.


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Arecaceae Calamoideae Calameae Salaccinae Salacca

Cucumber peeling cupredoxin-like protein

Phytocyanin

Disordered


Disordered

Acidic residues

Basic and acidic residues


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Pyraloidea Crambidae Spilomelinae Leucinodes

Helical

Helical

Helical

Pathak J.
Thiruvengadam V.
Gracy G.R.
M M.


Nusbaum C.
Zody M.C.
Borowsky M.L.
Kamal M.
Kodira C.D.
Taylor T.D.
Whittaker C.A.
Chang J.L.
Cuomo C.A.
Dewar K.
FitzGerald M.G.
Yang X.
Abouelleil A.
Allen N.R.
Anderson S.
Bloom T.
Bugalter B.
Butler J.
Cook A.
DeCaprio D.
Engels R.
Garber M.
Gnirke A.
Hafez N.
Hall J.L.
Norman C.H.
Itoh T.
Jaffe D.B.
Kuroki Y.
Lehoczky J.
Lui A.
Macdonald P.
Mauceli E.
Mikkelsen T.S.
Naylor J.W.
Nicol R.
Nguyen C.
Noguchi H.
O'Leary S.B.
O'Neill K.
Piqani B.
Smith C.L.
Talamas J.A.
Topham K.
Totoki Y.
Toyoda A.
Wain H.M.
Young S.K.
Zeng Q.
Zimmer A.R.
Fujiyama A.
Hattori M.
Birren B.W.
Sakaki Y.
Lander E.S.

DNA sequence and analysis of human chromosome 18.


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Lycosoidea Lycosidae Pardosa

NPC intracellular cholesterol transporter 2-like protein

MD-2-related lipid-recognition


Helical


Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Trombidiformes Prostigmata Eleutherengona Heterostigmata Tarsonemoidea Tarsonemidae Polyphagotarsonemus

Helical

Helical

Helical

Helical

Helical

Helical

Helical

Disordered

Disordered

Disordered

Polar residues

Polar residues

Low complexity


Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Rosales Elaeagnaceae Hippophae

MADS-box

Zhao J.
Xu Y.
Zhang Z.
Zhao M.
Li K.
Wang F.
Sun K.

Genome-wide analysis of the MADS-box gene family of sea buckthorn (Hippophae rhamnoides ssp. sinensis) and their potential role in floral organ development.

F:DNA-binding transcription factor activity, RNA polymerase II-specific

F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

P:positive regulation of transcription by RNA polymerase II


Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Penicillium

Moroz O.V.
Blagova E.
Lebedev A.A.
Skov L.K.
Pache R.A.
Schnorr K.M.
Kiemer L.
Friis E.P.
Nymand-Grarup S.
Ming L.
Ye L.
Klausen M.
Cohn M.T.
Schmidt E.G.W.
Davies G.J.
Wilson K.S.

Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases.

X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH ZN(2+)


Helical

Helical

Helical

Helical


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Endopterygota Lepidoptera Glossata Ditrysia Noctuoidea Noctuidae Hadeninae Mythimna

Identification and sex expression profiles of olfactory-related genes in Mythimna loreyi based on antennal transcriptome analysis.

Pheromone/general odorant binding protein domain


Eukaryota Metazoa Spiralia Lophotrochozoa Annelida Clitellata Oligochaeta Enchytraeida Enchytraeidae Enchytraeus

HMG box

HMG box

Disordered

Disordered

Disordered

Basic and acidic residues

Accumulation of soxC-expressing cells facilitated by MMPreg in the blastema formation in annelid Enchytraeus japonensis.

F:DNA-binding transcription activator activity, RNA polymerase II-specific

P:negative regulation of transcription by RNA polymerase II


Eukaryota Metazoa Porifera Demospongiae Verongimorpha Chondrillida Halisarcidae Halisarca

Helical

Helical

Helical

Helical

Helical

Helical

Helical

Rhodopsin 7-helix transmembrane proteins

Family A G protein-coupled receptor-like


Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Paraneoptera Hemiptera Sternorrhyncha Coccoidea Pseudococcidae Maconellicoccus

axial binding residue

Selvamani S.B.
Negi N.
Nagarjuna Reddy K.V.
Ramasamy G.G.

Identification of Cytochrome P450s in Maconellicoccus hirsutus.

F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus

Disordered

Church D.M.
Goodstadt L.
Hillier L.W.
Zody M.C.
Goldstein S.
She X.
Bult C.J.
Agarwala R.
Cherry J.L.
DiCuccio M.
Hlavina W.
Kapustin Y.
Meric P.
Maglott D.
Birtle Z.
Marques A.C.
Graves T.
Zhou S.
Teague B.
Potamousis K.
Churas C.
Place M.
Herschleb J.
Runnheim R.
Forrest D.
Amos-Landgraf J.
Schwartz D.C.
Cheng Z.
Lindblad-Toh K.
Eichler E.E.
Ponting C.P.

Lineage-specific biology revealed by a finished genome assembly of the mouse.

Church D.M.
Schneider V.A.
Graves T.
Auger K.
Cunningham F.
Bouk N.
Chen H.C.
Agarwala R.
McLaren W.M.
Ritchie G.R.
Albracht D.
Kremitzki M.
Rock S.
Kotkiewicz H.
Kremitzki C.
Wollam A.
Trani L.
Fulton L.
Fulton R.
Matthews L.
Whitehead S.
Chow W.
Torrance J.
Dunn M.
Harden G.
Threadgold G.
Wood J.
Collins J.
Heath P.
Griffiths G.
Pelan S.
Grafham D.
Eichler E.E.
Weinstock G.
Mardis E.R.
Wilson R.K.
Howe K.
Flicek P.
Hubbard T.

Modernizing reference genome assemblies.