diff --git a/0179e628a853118df9da75d50a227d9cf3c9b00dfa8825f8efe5e29d0d1c5f4c/metadata.json b/0179e628a853118df9da75d50a227d9cf3c9b00dfa8825f8efe5e29d0d1c5f4c/metadata.json
index 9116d6af49fe6f378b5fc9feb354d659db26ab17..626ca8da3ab07e7fbbf22f38a43a52068fa6db8b 100644
--- a/0179e628a853118df9da75d50a227d9cf3c9b00dfa8825f8efe5e29d0d1c5f4c/metadata.json
+++ b/0179e628a853118df9da75d50a227d9cf3c9b00dfa8825f8efe5e29d0d1c5f4c/metadata.json
@@ -152,5 +152,15 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3192096/v1/d533a98e60d481b64d76f77d.pdf"
+        },
+        {
+            "title": "LiSbatterysensing.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3192096/v1/0007492f0a351a611cbd139c.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/02381398ad3c168dad4fb3121959ba38b9f694fc8f5d7aeae79ef0842f4b081a/metadata.json b/02381398ad3c168dad4fb3121959ba38b9f694fc8f5d7aeae79ef0842f4b081a/metadata.json
index aad38829058eb1749b26578bd3fc54c831933dd9..83b46516d305914f94427f83b8c9895a4688dc1a 100644
--- a/02381398ad3c168dad4fb3121959ba38b9f694fc8f5d7aeae79ef0842f4b081a/metadata.json
+++ b/02381398ad3c168dad4fb3121959ba38b9f694fc8f5d7aeae79ef0842f4b081a/metadata.json
@@ -149,5 +149,11 @@
             "section_text": "Journal of Translational Medicine (2025)\n\nGenome Biology (2025)\n\nJournal of Translational Medicine (2025)\n\nNature Methods (2025)\n\nNature Machine Intelligence (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supptable1.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2824971/v1/34c203f3b243edff727bc1b4.csv"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0297e09c8c2b5e744ded2ba5e84ab6868857ddbdce0ca65775323250f8a61cea/metadata.json b/0297e09c8c2b5e744ded2ba5e84ab6868857ddbdce0ca65775323250f8a61cea/metadata.json
index 57560bfc365fb545609f2de9f1ce9b12957bf851..9d2ff69f37250f37fa1d90766e2b835959789848 100644
--- a/0297e09c8c2b5e744ded2ba5e84ab6868857ddbdce0ca65775323250f8a61cea/metadata.json
+++ b/0297e09c8c2b5e744ded2ba5e84ab6868857ddbdce0ca65775323250f8a61cea/metadata.json
@@ -182,5 +182,11 @@
             "section_text": "Environmental Sciences Europe (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nScientific Reports (2025)\n\nNature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupportingInformation100MB.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-420056/v1/3ea785aebd64a3523798e40b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/02f5f0062184ad10aa0c00a66e174b8fdaab83aacddedff0b58a36c9878f2849/metadata.json b/02f5f0062184ad10aa0c00a66e174b8fdaab83aacddedff0b58a36c9878f2849/metadata.json
index e63144b3cda70348d45b144903743b2a2c161e11..9da785abd00894288abe88f8111793e56d4c2157 100644
--- a/02f5f0062184ad10aa0c00a66e174b8fdaab83aacddedff0b58a36c9878f2849/metadata.json
+++ b/02f5f0062184ad10aa0c00a66e174b8fdaab83aacddedff0b58a36c9878f2849/metadata.json
@@ -237,5 +237,15 @@
             "section_text": "Nature Methods (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nPhotoniX (2024)\n\nNature Reviews Methods Primers (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "20220523DLAOSupplementssubmit.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1690151/v1/a5d8fed858c76c3cf0850573.pdf"
+        },
+        {
+            "title": "SupplementaryVideos.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1690151/v1/6d44cc4454b83382cf883e0c.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0358cbd719cad92a5106a1d23b164c7a9ee9af38881e700bf32a1c27078c4f3f/metadata.json b/0358cbd719cad92a5106a1d23b164c7a9ee9af38881e700bf32a1c27078c4f3f/metadata.json
index 99422238a08085c16809a2315194db10a4ac10af..4d73c810e101b930b3c15ad9ae1ef2772bb4a387 100644
--- a/0358cbd719cad92a5106a1d23b164c7a9ee9af38881e700bf32a1c27078c4f3f/metadata.json
+++ b/0358cbd719cad92a5106a1d23b164c7a9ee9af38881e700bf32a1c27078c4f3f/metadata.json
@@ -130,5 +130,11 @@
             "section_text": "Nature Reviews Chemistry (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinginformation5.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3910735/v1/a723a7953ceff6e16f8deb7b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/03d68cf8e193cb35c9be6144c0f8c2e40f012dc558e3da2c1ab952dea9dac6d5/metadata.json b/03d68cf8e193cb35c9be6144c0f8c2e40f012dc558e3da2c1ab952dea9dac6d5/metadata.json
index c5674316906ff27cc6a28ebc6baa549317d8f54f..b60eca2e2c311ec821ddaa7f6e3ecf834faebca7 100644
--- a/03d68cf8e193cb35c9be6144c0f8c2e40f012dc558e3da2c1ab952dea9dac6d5/metadata.json
+++ b/03d68cf8e193cb35c9be6144c0f8c2e40f012dc558e3da2c1ab952dea9dac6d5/metadata.json
@@ -139,5 +139,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3884985/v1/53b8864822df5bb4e615a5ef.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/078ee3115bb7f9caf7ff08bd41325e1b3d5bc1c68c6da418cda25d198e700819/metadata.json b/078ee3115bb7f9caf7ff08bd41325e1b3d5bc1c68c6da418cda25d198e700819/metadata.json
index 45c1ffb9e9f4e9b505c9738de5a4cb3984c59af7..7a7fdfbab31f19b89ca54bb19a9591f0cf219c42 100644
--- a/078ee3115bb7f9caf7ff08bd41325e1b3d5bc1c68c6da418cda25d198e700819/metadata.json
+++ b/078ee3115bb7f9caf7ff08bd41325e1b3d5bc1c68c6da418cda25d198e700819/metadata.json
@@ -132,5 +132,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIFinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5061922/v1/a0a8713ba410218cdaf04387.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/07f28e497a966d2241ff131830d461c8058880986d6873f21a89c91e352b254e/metadata.json b/07f28e497a966d2241ff131830d461c8058880986d6873f21a89c91e352b254e/metadata.json
index bda2f336595ed170211291c97ae6d59a67dccc35..394367566c98a0f81cf5615d1386b2638ebacaa6 100644
--- a/07f28e497a966d2241ff131830d461c8058880986d6873f21a89c91e352b254e/metadata.json
+++ b/07f28e497a966d2241ff131830d461c8058880986d6873f21a89c91e352b254e/metadata.json
@@ -173,5 +173,11 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinginformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3799527/v1/68baddb59f62515acd8f3609.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/084645ecaf0633670ce86e9b62f37cf8c911eec46c0e61646e18f05eb546a1be/metadata.json b/084645ecaf0633670ce86e9b62f37cf8c911eec46c0e61646e18f05eb546a1be/metadata.json
index 80498255425dcb5297803eaeef1a8652332348dc..429b0f09d88360cfe85576813bb4f01049886d05 100644
--- a/084645ecaf0633670ce86e9b62f37cf8c911eec46c0e61646e18f05eb546a1be/metadata.json
+++ b/084645ecaf0633670ce86e9b62f37cf8c911eec46c0e61646e18f05eb546a1be/metadata.json
@@ -178,5 +178,11 @@
             "section_text": "Nature Communications (2025)\n\nCommunications Biology (2025)\n\nNature Computational Science (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryinformationPGMGAPharmacophoreGuidedDeepLearningApproachforBioactiveMolecularGeneration.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1749921/v1/4b2403f6a8624a9c146b7f70.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0a57595338b1390798459ee5d63f40d3108931b635b32aecd97babb2ece11f54/metadata.json b/0a57595338b1390798459ee5d63f40d3108931b635b32aecd97babb2ece11f54/metadata.json
index d4a34a4320e86050736153bd4c0fbf2a91b13c4d..0b6dae274a87b36d23038e82b40c67e0293cf8a9 100644
--- a/0a57595338b1390798459ee5d63f40d3108931b635b32aecd97babb2ece11f54/metadata.json
+++ b/0a57595338b1390798459ee5d63f40d3108931b635b32aecd97babb2ece11f54/metadata.json
@@ -201,5 +201,19 @@
             "section_text": "Cell Death & Differentiation (2025)\n\nNature Communications (2024)\n\nCell Death & Differentiation (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Video1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1196040/v1/7c38c705e98e6e5c8cd38d4c.mp4"
+        },
+        {
+            "title": "Video2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1196040/v1/9c841af5fb060ae1b74cae15.mp4"
+        },
+        {
+            "title": "Video3.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1196040/v1/7f75dddbf51e7dbffe85d9bd.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0b1a0b4aec6a90ace8891c1807e0877f3f0920fddeddfa564eaec78950d02f91/metadata.json b/0b1a0b4aec6a90ace8891c1807e0877f3f0920fddeddfa564eaec78950d02f91/metadata.json
index 368c97ad22b372028360c0ca532f56dc3ffa2c4b..e89b5da521ab7a06b26e43aa68de784a11777c7b 100644
--- a/0b1a0b4aec6a90ace8891c1807e0877f3f0920fddeddfa564eaec78950d02f91/metadata.json
+++ b/0b1a0b4aec6a90ace8891c1807e0877f3f0920fddeddfa564eaec78950d02f91/metadata.json
@@ -227,5 +227,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4664717/v1/6d53b7533e7cc64001e91a75.zip"
+        },
+        {
+            "title": "SupplementaryMovie.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4664717/v1/b0a5c1c16f983e1608f393a5.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0b483a72e0c58a9950db9f28aced8eb28f2145605ee9fc9e2c0f9dd377ab37bd/metadata.json b/0b483a72e0c58a9950db9f28aced8eb28f2145605ee9fc9e2c0f9dd377ab37bd/metadata.json
index c51cfc1d703bcee9c01bd147af8b25f19bec00c3..23e3dfcfda6327579ce60401613cf9ec7bd616bd 100644
--- a/0b483a72e0c58a9950db9f28aced8eb28f2145605ee9fc9e2c0f9dd377ab37bd/metadata.json
+++ b/0b483a72e0c58a9950db9f28aced8eb28f2145605ee9fc9e2c0f9dd377ab37bd/metadata.json
@@ -167,5 +167,15 @@
             "section_text": "Nature Communications (2025)\n\nGenome Biology (2024)\n\nBMC Genomics (2024)\n\nNature Communications (2022)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-123595/v1/453122938a75bc6da059be86.pdf"
+        },
+        {
+            "title": "SupplementaryNotes.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-123595/v1/2698e1009cc24aead5171edb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0b538509c064388ebcba1020095176d4c755cf1c8ab70bd62ccaf543682f74dd/metadata.json b/0b538509c064388ebcba1020095176d4c755cf1c8ab70bd62ccaf543682f74dd/metadata.json
index ab5848e752a7536e1b19e035e0e5f868e5b9d8ba..1c4fcd2e9154dc66e464f12ba16ee313ea6b28bd 100644
--- a/0b538509c064388ebcba1020095176d4c755cf1c8ab70bd62ccaf543682f74dd/metadata.json
+++ b/0b538509c064388ebcba1020095176d4c755cf1c8ab70bd62ccaf543682f74dd/metadata.json
@@ -159,5 +159,11 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1104345/v1/23e013cf3a96bdf43802f38a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0b552d1a21ef43332bb18edc8636931c3ead50f43d2ebe1d1e7d8d0b0dc55a18/metadata.json b/0b552d1a21ef43332bb18edc8636931c3ead50f43d2ebe1d1e7d8d0b0dc55a18/metadata.json
index e15e9fad756ef287b9b61add0d1bc0846190985f..d4e379646dabc9da8477ffd10c302cf501cde79f 100644
--- a/0b552d1a21ef43332bb18edc8636931c3ead50f43d2ebe1d1e7d8d0b0dc55a18/metadata.json
+++ b/0b552d1a21ef43332bb18edc8636931c3ead50f43d2ebe1d1e7d8d0b0dc55a18/metadata.json
@@ -151,5 +151,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PACTOSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4283857/v1/4f74f8aba6991b03393e3129.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0b9fa4ed624e47e0feb3298b20fd61b8f8fc434f97c84e5e73e11eec0df23a0f/metadata.json b/0b9fa4ed624e47e0feb3298b20fd61b8f8fc434f97c84e5e73e11eec0df23a0f/metadata.json
index f7f25e128f41a9c9f8b147d0a1053fc412673640..92d77b94d89930229937cd314c265e6be12272a4 100644
--- a/0b9fa4ed624e47e0feb3298b20fd61b8f8fc434f97c84e5e73e11eec0df23a0f/metadata.json
+++ b/0b9fa4ed624e47e0feb3298b20fd61b8f8fc434f97c84e5e73e11eec0df23a0f/metadata.json
@@ -156,5 +156,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4253346/v1/bfab412c10b08d31f0d45b8a.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0c0fdd1f1980a187e682cbf3e5e869fcf82f48c1168f402cd0132e7122adb5fe/metadata.json b/0c0fdd1f1980a187e682cbf3e5e869fcf82f48c1168f402cd0132e7122adb5fe/metadata.json
index 8ebd66e181690d6c437addf798ad1dff281271f6..49163dcc9d358729d799b06b1a3e7450f5334b8b 100644
--- a/0c0fdd1f1980a187e682cbf3e5e869fcf82f48c1168f402cd0132e7122adb5fe/metadata.json
+++ b/0c0fdd1f1980a187e682cbf3e5e869fcf82f48c1168f402cd0132e7122adb5fe/metadata.json
@@ -148,5 +148,11 @@
             "section_text": "Journal of Materials Science (2025)\n\nCommunications Physics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "HexGeSiGeQWsExtendedData.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3875137/v1/b79c4116ddee278470d1c65e.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0c34a8e31faa7739408a5ccd9d2f5e997e03e8f8f88c468ddded81aa6cf416eb/metadata.json b/0c34a8e31faa7739408a5ccd9d2f5e997e03e8f8f88c468ddded81aa6cf416eb/metadata.json
index f8c19d5ab6faa8602cdc3175d59777ceee5289eb..07c94fba06a849f879da9570658533efa2b25abe 100644
--- a/0c34a8e31faa7739408a5ccd9d2f5e997e03e8f8f88c468ddded81aa6cf416eb/metadata.json
+++ b/0c34a8e31faa7739408a5ccd9d2f5e997e03e8f8f88c468ddded81aa6cf416eb/metadata.json
@@ -162,5 +162,15 @@
             "section_text": "BMC Genomics (2025)\n\nCommunications Biology (2025)\n\nBMC Genomics (2024)\n\nCommunications Biology (2024)\n\nFisheries Science (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PolicarpoetalSupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2922188/v1/3c54c8e2dd9b5d4d5c1c0d60.pdf"
+        },
+        {
+            "title": "PolicarpoetalSupplementaryFile1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2922188/v1/7f3ddc25780350d599f35b98.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/0f43ab377913d883885fc5b793f1a6d8dbf89b2a4f2bd4ee445349870e3187e4/metadata.json b/0f43ab377913d883885fc5b793f1a6d8dbf89b2a4f2bd4ee445349870e3187e4/metadata.json
index 851d36e174f88734e477e6f5028d2ff642a3a1b1..e85290e4f7790204fde8e254dc8d2c1e6f586a4f 100644
--- a/0f43ab377913d883885fc5b793f1a6d8dbf89b2a4f2bd4ee445349870e3187e4/metadata.json
+++ b/0f43ab377913d883885fc5b793f1a6d8dbf89b2a4f2bd4ee445349870e3187e4/metadata.json
@@ -142,5 +142,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryMaterials.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4521626/v1/57c946f7826418ded4c3ca98.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1014f2957f8a5a80f5a91706c1899e6dcb17ad8f638e3ae989055850203d6b05/metadata.json b/1014f2957f8a5a80f5a91706c1899e6dcb17ad8f638e3ae989055850203d6b05/metadata.json
index c7ab776d183dd7109dee771e49ced81e2a8a7c07..4000d96c711d8811fdb10aa80ed31a80f8d3c78d 100644
--- a/1014f2957f8a5a80f5a91706c1899e6dcb17ad8f638e3ae989055850203d6b05/metadata.json
+++ b/1014f2957f8a5a80f5a91706c1899e6dcb17ad8f638e3ae989055850203d6b05/metadata.json
@@ -188,5 +188,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Reviews Materials (2025)\n\nNature Communications (2025)\n\nScience China Technological Sciences (2025)\n\nStructural and Multidisciplinary Optimization (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3325404/v1/a9979b42303005609a7ba4e2.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/106ed737032cb1e9ae45bb1817b5293def30e028c91669ed59e1c3aaa5a66382/metadata.json b/106ed737032cb1e9ae45bb1817b5293def30e028c91669ed59e1c3aaa5a66382/metadata.json
index de1ac5ff8a21052b5162a40a920f288223ebaab7..5ff71fe8eaef8bccb925cbfd850b264458cdaa23 100644
--- a/106ed737032cb1e9ae45bb1817b5293def30e028c91669ed59e1c3aaa5a66382/metadata.json
+++ b/106ed737032cb1e9ae45bb1817b5293def30e028c91669ed59e1c3aaa5a66382/metadata.json
@@ -160,5 +160,19 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TablesforSubmission.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502164/v1/24b8a571ed6b5559ebcb6c59.xlsx"
+        },
+        {
+            "title": "SupplementaryFigures.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502164/v1/7ff1275a0448ad25d0a3709b.docx"
+        },
+        {
+            "title": "nrreportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502164/v1/f7c9c59db277ce1591c28ffa.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/132662067fd4339398b4b0c2aa91a488cb53e3b3cb0af5e8f911aa65e93e02e9/metadata.json b/132662067fd4339398b4b0c2aa91a488cb53e3b3cb0af5e8f911aa65e93e02e9/metadata.json
index 4230bf98b8f09f64594c2bd7c58568081e342e63..b125a59b8ad00f62a9ad410f246716038a98b99e 100644
--- a/132662067fd4339398b4b0c2aa91a488cb53e3b3cb0af5e8f911aa65e93e02e9/metadata.json
+++ b/132662067fd4339398b4b0c2aa91a488cb53e3b3cb0af5e8f911aa65e93e02e9/metadata.json
@@ -188,5 +188,23 @@
             "section_text": "Nature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3658321/v1/5494ad997874060157ad2c12.xlsx"
+        },
+        {
+            "title": "supplementarytable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3658321/v1/4707fcc9677e59a2e421a326.xlsx"
+        },
+        {
+            "title": "supplementarytable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3658321/v1/dffab191848a935beca6c68f.xlsx"
+        },
+        {
+            "title": "appendixversion20231123.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3658321/v1/1612990e285826189f1ecc6d.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/145ed7adfa8e827fc921eb2a50da5c2f08269c3626b08d3369b33afe80b71ca3/metadata.json b/145ed7adfa8e827fc921eb2a50da5c2f08269c3626b08d3369b33afe80b71ca3/metadata.json
index a8932e2f3597bd45bd15faefa26f673ba61a4d99..c1c07cfb84fac4ab1352d53468da055cc0b17046 100644
--- a/145ed7adfa8e827fc921eb2a50da5c2f08269c3626b08d3369b33afe80b71ca3/metadata.json
+++ b/145ed7adfa8e827fc921eb2a50da5c2f08269c3626b08d3369b33afe80b71ca3/metadata.json
@@ -176,5 +176,19 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MisicREADME.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1296849/v1/fc621035041d80d4a0bd1641.txt"
+        },
+        {
+            "title": "misiccodeflat.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1296849/v1/5b135c5bb21da69dd36b2740.pdf"
+        },
+        {
+            "title": "misicepcflat.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1296849/v1/196e0d44f016ed37bb1a4c01.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/153c75710118b92bafb57fed0d1a10e7b3e9c3d4534e94d2b0e9e7f8db26d4f2/metadata.json b/153c75710118b92bafb57fed0d1a10e7b3e9c3d4534e94d2b0e9e7f8db26d4f2/metadata.json
index 555fe61b8adab0e514822753f1ac3cffecea40cd..4f4a87235120ca8d40a0404bce2b91b0533001ca 100644
--- a/153c75710118b92bafb57fed0d1a10e7b3e9c3d4534e94d2b0e9e7f8db26d4f2/metadata.json
+++ b/153c75710118b92bafb57fed0d1a10e7b3e9c3d4534e94d2b0e9e7f8db26d4f2/metadata.json
@@ -176,5 +176,11 @@
             "section_text": "European Journal of Medical Research (2025)\n\nJournal of Molecular Evolution (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PhylogeographieBoDV1Supplementalsv7231117final.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3640627/v1/da147469f1d902fcdfbc60bd.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/15e32c906ddaf0e1f177d7ed66d4fa3b64eaa6a4da72a59a15b72c91a3f8fa39/metadata.json b/15e32c906ddaf0e1f177d7ed66d4fa3b64eaa6a4da72a59a15b72c91a3f8fa39/metadata.json
index 0fe1ce2615872a5639bcab076bb48e789a35ee79..f821a69cb98777b4227b24a4f83a11771d324584 100644
--- a/15e32c906ddaf0e1f177d7ed66d4fa3b64eaa6a4da72a59a15b72c91a3f8fa39/metadata.json
+++ b/15e32c906ddaf0e1f177d7ed66d4fa3b64eaa6a4da72a59a15b72c91a3f8fa39/metadata.json
@@ -165,5 +165,11 @@
             "section_text": "Communications Biology (2025)\n\nNature Communications (2025)\n\nScientific Reports (2024)\n\nScientific Reports (2024)\n\nBrain Structure and Function (2022)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NCsupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-209477/v1/5e0b74b27246543b4cdebc97.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/16297f08d4bee87d91d82e52bb78067c2240415f69e31ec84422d74b9d45fb14/metadata.json b/16297f08d4bee87d91d82e52bb78067c2240415f69e31ec84422d74b9d45fb14/metadata.json
index 9dc3e9565d4f3aed8644c2200c59078557ad4440..9e3e27a754985422e8c705edcf06a9e3787f685f 100644
--- a/16297f08d4bee87d91d82e52bb78067c2240415f69e31ec84422d74b9d45fb14/metadata.json
+++ b/16297f08d4bee87d91d82e52bb78067c2240415f69e31ec84422d74b9d45fb14/metadata.json
@@ -172,5 +172,51 @@
             "section_text": "Nature Climate Change (2025)\n\nNature Geoscience (2025)\n\nClimate Dynamics (2025)\n\nSurveys in Geophysics (2025)\n\nSurveys in Geophysics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendedDataFig1.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/d800761807945091584f3414.docx"
+        },
+        {
+            "title": "ExtendedDataFig2.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/58bdd66411abd884d36fa780.docx"
+        },
+        {
+            "title": "ExtendedDataFig3.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/8b5abe96b6331dc61fbe1c5b.docx"
+        },
+        {
+            "title": "ExtendedDataFig4.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/e39e099efa860b5352b1f878.docx"
+        },
+        {
+            "title": "ExtendedDataFig5.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/cb730564861f83cec0b99676.docx"
+        },
+        {
+            "title": "ExtendedDataTable1.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/89991d707611dc2829418773.docx"
+        },
+        {
+            "title": "ExtendedDataTable2.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/46a44ed7fcf232adfc31281d.docx"
+        },
+        {
+            "title": "ExtendedDataTable3.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/7b8fd7d321a73c574c5f7340.docx"
+        },
+        {
+            "title": "ExtendedDataTable4.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/f1bea240c5b4e18984b83352.docx"
+        },
+        {
+            "title": "SupplementaryInformationREFSForExtDataTab1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/bef2dedc8b36aa35f5e2626d.pdf"
+        },
+        {
+            "title": "SupplementaryInformationRegressionMethods.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-588180/v1/70797c6e8cfd72f36205203f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/18158261c310b7c6dd7cffda49c0a19498925ef75bcacf1310f2fdd18b6009d4/metadata.json b/18158261c310b7c6dd7cffda49c0a19498925ef75bcacf1310f2fdd18b6009d4/metadata.json
index 3fc7980eb45ed57c82d6a6b5502d40017b174d3b..93469ddbdf9c2569fff49eeffebbbce3037d7f1b 100644
--- a/18158261c310b7c6dd7cffda49c0a19498925ef75bcacf1310f2fdd18b6009d4/metadata.json
+++ b/18158261c310b7c6dd7cffda49c0a19498925ef75bcacf1310f2fdd18b6009d4/metadata.json
@@ -175,5 +175,31 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "DTTEA2118C15H20Cl20m.cif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/48099dc6c3cfa3601473ea50.cif"
+        },
+        {
+            "title": "DTTEA2118C15H20Cl20mcifreport.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/6bd991d2dd250029c2c2e7d9.pdf"
+        },
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/ce9054add795da6c637c7da3.pdf"
+        },
+        {
+            "title": "TEADT2103C28H26O40m.cif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/dfed6f76d40cebc223303795.cif"
+        },
+        {
+            "title": "Schemes.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/126f3e2a11b484238266b649.docx"
+        },
+        {
+            "title": "TEADT2103C28H26O40mcifreport.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3464061/v1/966f2db15023508de84b86fc.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/19b1d6b59efd7b19368f5003a25f24e86cf87b8704c446aba11acfc2ee49035d/metadata.json b/19b1d6b59efd7b19368f5003a25f24e86cf87b8704c446aba11acfc2ee49035d/metadata.json
index 799aa641170bbc07059c45bf0c7b73bc91194713..03d4de89a76fe613ec16a863b57f3bada3772405 100644
--- a/19b1d6b59efd7b19368f5003a25f24e86cf87b8704c446aba11acfc2ee49035d/metadata.json
+++ b/19b1d6b59efd7b19368f5003a25f24e86cf87b8704c446aba11acfc2ee49035d/metadata.json
@@ -144,5 +144,15 @@
             "section_text": "Cell Communication and Signaling (2025)\n\nNature Communications (2024)\n\nCommunications Biology (2024)\n\nEnvironmental Geochemistry and Health (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIMaTiming.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2674610/v1/07a6608615bf8bbaafb153cb.pdf"
+        },
+        {
+            "title": "NCOMMS23104031rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2674610/v1/650cf98f8a13462cafcd2410.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/19bda13049657c47ac8ce1738b38ad6f68e526634bef3af918450a2a87211656/metadata.json b/19bda13049657c47ac8ce1738b38ad6f68e526634bef3af918450a2a87211656/metadata.json
index c844a269343f2f648c6816f423c41e6f2897ccac..fd92ee1b79a9c2da5ed5dedbbec16f730bcdcf86 100644
--- a/19bda13049657c47ac8ce1738b38ad6f68e526634bef3af918450a2a87211656/metadata.json
+++ b/19bda13049657c47ac8ce1738b38ad6f68e526634bef3af918450a2a87211656/metadata.json
@@ -146,5 +146,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformations.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4950329/v1/4a4073b64f3260237c9169f6.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1aa1b3149c7dd2680c529ca5e227196508ccef24c8293f3589b91464342cb633/metadata.json b/1aa1b3149c7dd2680c529ca5e227196508ccef24c8293f3589b91464342cb633/metadata.json
index 5f40b2c885240d946478a74be0ae47efddc39090..1571b11760e1747b0650b0dba632c91315a83274 100644
--- a/1aa1b3149c7dd2680c529ca5e227196508ccef24c8293f3589b91464342cb633/metadata.json
+++ b/1aa1b3149c7dd2680c529ca5e227196508ccef24c8293f3589b91464342cb633/metadata.json
@@ -134,5 +134,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "GencoetalSupplementaryInfo.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4521415/v1/28852a83ec3487aac70f98b7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1afa229c8deb549ae72a63b676ea4be6c76cc06e3602f377ba3a49d77e5238b3/metadata.json b/1afa229c8deb549ae72a63b676ea4be6c76cc06e3602f377ba3a49d77e5238b3/metadata.json
index 97fe659e571ef71c47bec8b1f1ee3ee42166fd99..9a28bfc446d76ef127d4a8781446cc5492522091 100644
--- a/1afa229c8deb549ae72a63b676ea4be6c76cc06e3602f377ba3a49d77e5238b3/metadata.json
+++ b/1afa229c8deb549ae72a63b676ea4be6c76cc06e3602f377ba3a49d77e5238b3/metadata.json
@@ -188,5 +188,39 @@
             "section_text": "Nature Biomedical Engineering (2025)\n\nJournal of Translational Medicine (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplMovie1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/ccec3e5965423c3495b87bab.mp4"
+        },
+        {
+            "title": "SupplMovie2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/2839bc6b6adbeadce8d4604d.mp4"
+        },
+        {
+            "title": "SupplMovie3.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/3fd42e8b4caba2d89879a0d0.mp4"
+        },
+        {
+            "title": "SupplMovie4.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/a193864494db5804c3da22b5.mp4"
+        },
+        {
+            "title": "SupplMovie5.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/0702934c542af189b21939bf.mp4"
+        },
+        {
+            "title": "SupplMovie6.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/71b4dcc5967fa1563a6328a0.mp4"
+        },
+        {
+            "title": "SupplMovie7.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/7e7a39053d076a577f3f1b6c.mp4"
+        },
+        {
+            "title": "SupplementaryInformationSandozKuhnigk2022.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2371463/v1/b9bfb8cfc880035286fa153a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1b6c1006597cec0e09d875f81d5f626f91450dd63ffcf131a78beae5d4796310/metadata.json b/1b6c1006597cec0e09d875f81d5f626f91450dd63ffcf131a78beae5d4796310/metadata.json
index ca22fef95898dd1032ba533e07b5bc1f38126383..49f241fe77ad1f56d712008fe583ae80bb29b044 100644
--- a/1b6c1006597cec0e09d875f81d5f626f91450dd63ffcf131a78beae5d4796310/metadata.json
+++ b/1b6c1006597cec0e09d875f81d5f626f91450dd63ffcf131a78beae5d4796310/metadata.json
@@ -163,5 +163,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "LIBmaterialCFSINatComms.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4385579/v1/54d030bca0d2f7c59af67adf.pdf"
+        },
+        {
+            "title": "NatCommsReviewLIBmaterialCFsubmissionrepo.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4385579/v1/dbdf95b427336cccf2b4b71a.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1db1c6bb3f404505c99e03eb48d565d2d10f08aec36dfc093a647d410779a465/metadata.json b/1db1c6bb3f404505c99e03eb48d565d2d10f08aec36dfc093a647d410779a465/metadata.json
index 4f7dd9770e383a3de183a118d51c1eeedc7e9466..f96c9d3f3421a228302052dcbc7343780c01b508 100644
--- a/1db1c6bb3f404505c99e03eb48d565d2d10f08aec36dfc093a647d410779a465/metadata.json
+++ b/1db1c6bb3f404505c99e03eb48d565d2d10f08aec36dfc093a647d410779a465/metadata.json
@@ -201,5 +201,19 @@
             "section_text": "Scientific Data (2025)\n\nNature Methods (2025)\n\nNature Methods (2025)\n\nNature Neuroscience (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TableS1SEUALLENbrains0615.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3146034/v1/7b7edee36c428b1bb1b56306.xlsx"
+        },
+        {
+            "title": "TableS2somaregion314counts.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3146034/v1/8b4b322acbcace3e7f169b12.xlsx"
+        },
+        {
+            "title": "Tables3Somamorphometry.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3146034/v1/8907ba8c59008968002446a9.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1efc61cb1a3025a54ee34fc3952670a04ac4c14e6eced586791d11b831c53662/metadata.json b/1efc61cb1a3025a54ee34fc3952670a04ac4c14e6eced586791d11b831c53662/metadata.json
index c06ca77ad7e2128d48e6e5d763e4e5f445a695bd..de3c79cf8267049c63d7af2562ba11da3073a416 100644
--- a/1efc61cb1a3025a54ee34fc3952670a04ac4c14e6eced586791d11b831c53662/metadata.json
+++ b/1efc61cb1a3025a54ee34fc3952670a04ac4c14e6eced586791d11b831c53662/metadata.json
@@ -169,5 +169,11 @@
             "section_text": "npj Parkinson's Disease (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MSDNAJC12SupplementaryFiguresFINAL.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3621320/v1/11df684143ffec53d780f1fb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/1fdd6716183b848b4cb6460ca8ad882add822f660a1ffea2933c3b9322d7296b/metadata.json b/1fdd6716183b848b4cb6460ca8ad882add822f660a1ffea2933c3b9322d7296b/metadata.json
index a5185cd065911bbc2f33d5be1a6dcb31870deb38..b54f0edee98ea2377f82530cded8fec14890eb3b 100644
--- a/1fdd6716183b848b4cb6460ca8ad882add822f660a1ffea2933c3b9322d7296b/metadata.json
+++ b/1fdd6716183b848b4cb6460ca8ad882add822f660a1ffea2933c3b9322d7296b/metadata.json
@@ -199,5 +199,39 @@
             "section_text": "Nature (2025)\n\nEMBO Reports (2025)\n\nThe EMBO Journal (2025)\n\nScientific Reports (2025)\n\nLeukemia (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/649d577d88a1c9df116c8361.xlsx"
+        },
+        {
+            "title": "TableS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/7f5fc0aab427a0d6cf5d0c3a.xlsx"
+        },
+        {
+            "title": "TableS3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/55ab807bbe160c4c944632e8.xlsx"
+        },
+        {
+            "title": "TableS4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/016e5bb30d23a882d1d3baa0.xlsx"
+        },
+        {
+            "title": "TableS5.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/d2d3b279a91c23b2e7d05d88.xlsx"
+        },
+        {
+            "title": "TableS6.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/5ffd36d265d5a4eba290b9db.xlsx"
+        },
+        {
+            "title": "TableS7.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/2dea8be706b35fe4ca76625d.xlsx"
+        },
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-228624/v1/e3f7e5b6944865a4747ef1b8.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/20d628b86a95a908ca6a3eea75be8551f429d2e01345048d6cf0538c033a4320/metadata.json b/20d628b86a95a908ca6a3eea75be8551f429d2e01345048d6cf0538c033a4320/metadata.json
index cf63b64fc2f6f84d7dcb383ee834ecf8c5815551..32691b177b4f2a7ff2381f6219abf3286bb93032 100644
--- a/20d628b86a95a908ca6a3eea75be8551f429d2e01345048d6cf0538c033a4320/metadata.json
+++ b/20d628b86a95a908ca6a3eea75be8551f429d2e01345048d6cf0538c033a4320/metadata.json
@@ -168,5 +168,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3074097/v2/5c937fed61184c7229b7c335.pdf"
+        },
+        {
+            "title": "SIdata230912.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3074097/v2/12e051056e7b1e8d21ff1d23.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/243a49347fe121c89fd5ff68e321ef2745156e92ca32c99a7c5615dbaa8c8978/metadata.json b/243a49347fe121c89fd5ff68e321ef2745156e92ca32c99a7c5615dbaa8c8978/metadata.json
index 95e2938a7c0752efe944b25db301fca86f7fe887..a438dbf7f2d34fa89147723d44a1742a58cdfe54 100644
--- a/243a49347fe121c89fd5ff68e321ef2745156e92ca32c99a7c5615dbaa8c8978/metadata.json
+++ b/243a49347fe121c89fd5ff68e321ef2745156e92ca32c99a7c5615dbaa8c8978/metadata.json
@@ -230,5 +230,27 @@
             "section_text": "Genome Biology (2025)\n\nNature Structural & Molecular Biology (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendeddataTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3620990/v1/30e4f2030e9045eb2e55cf7e.xlsx"
+        },
+        {
+            "title": "ExtendeddataTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3620990/v1/624d6a8cfd0b7d9c2b5d32b0.xlsx"
+        },
+        {
+            "title": "ExtendeddataTable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3620990/v1/2cad917c96758dbeab3d5f25.xlsx"
+        },
+        {
+            "title": "ExtendeddataTable4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3620990/v1/d8208cf4f111bc7b2c9ac484.xlsx"
+        },
+        {
+            "title": "ExtendeddataTable5.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3620990/v1/67379df9a1cebfb53502bc2d.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2492f6f288d727a159e794891f1e45651aa47c7b22e9847cc9b84e80832abd28/metadata.json b/2492f6f288d727a159e794891f1e45651aa47c7b22e9847cc9b84e80832abd28/metadata.json
index 9295ecbf78cbc5c27dafb7a5d4d61a40377a301c..300ef797a6e8dc48c569c61f4bafe45c07be1aaa 100644
--- a/2492f6f288d727a159e794891f1e45651aa47c7b22e9847cc9b84e80832abd28/metadata.json
+++ b/2492f6f288d727a159e794891f1e45651aa47c7b22e9847cc9b84e80832abd28/metadata.json
@@ -162,5 +162,23 @@
             "section_text": "Epigenetics & Chromatin (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "FRAPDMSO.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3232485/v1/a985801a13304129624ccf59.mov"
+        },
+        {
+            "title": "FRAPICRF193.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3232485/v1/f4b044c5d69aa1da2f384d8e.mov"
+        },
+        {
+            "title": "FRAPSumoiICRF.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3232485/v1/0448d3b62d8f448348ef4992.mov"
+        },
+        {
+            "title": "AmoiridisSupplementalInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3232485/v1/3ded7ab413d0565afc9a4035.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/24a008a37e7789b34262d8215ba6756a7305ebd33a8193fc1d1321c287f92d0b/metadata.json b/24a008a37e7789b34262d8215ba6756a7305ebd33a8193fc1d1321c287f92d0b/metadata.json
index 7e88536f7484d823f8db8f58d945b80e4e3d6a1b..76d7ec6bbc96b09abec3956a84176f923d4af71f 100644
--- a/24a008a37e7789b34262d8215ba6756a7305ebd33a8193fc1d1321c287f92d0b/metadata.json
+++ b/24a008a37e7789b34262d8215ba6756a7305ebd33a8193fc1d1321c287f92d0b/metadata.json
@@ -183,5 +183,43 @@
             "section_text": "Scientific Reports (2025)\n\nThe EMBO Journal (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nNature Plants (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Video1.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/c2a3c52814ee818ff7411c7d.avi"
+        },
+        {
+            "title": "Video2.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/f8e5b92ae6142b0088932b2b.avi"
+        },
+        {
+            "title": "Video3.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/f350b51a9627fdb65c78e2a6.avi"
+        },
+        {
+            "title": "Video4.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/729c94c760678dbbfc6a007a.avi"
+        },
+        {
+            "title": "Video5.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/0115a54418aa686b2a63b66d.avi"
+        },
+        {
+            "title": "Video6.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/d9bcff51d9ea678ae5076858.avi"
+        },
+        {
+            "title": "Video7.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/9a17658e4c094aeda11d02ff.avi"
+        },
+        {
+            "title": "Video8.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/bcee327e32c855d7b8a919c7.avi"
+        },
+        {
+            "title": "Video9.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2394535/v1/f9c0df68a9539b4fe6325d53.avi"
+        }
     ]
 }
\ No newline at end of file
diff --git a/24c60571af15012393da8ef2f5de83120e71d6efc863787fdb9352b894873949/metadata.json b/24c60571af15012393da8ef2f5de83120e71d6efc863787fdb9352b894873949/metadata.json
index 3bbe33c01cec14e946d9a2bb9c0259b8b8f435a8..7172751567bb8245d1ea61bf561e8f6698cb9507 100644
--- a/24c60571af15012393da8ef2f5de83120e71d6efc863787fdb9352b894873949/metadata.json
+++ b/24c60571af15012393da8ef2f5de83120e71d6efc863787fdb9352b894873949/metadata.json
@@ -188,5 +188,39 @@
             "section_text": "Naunyn-Schmiedeberg's Archives of Pharmacology (2025)\n\nBiomarker Research (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/01d12d6a5ecd7c619f7fa075.xlsx"
+        },
+        {
+            "title": "TableS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/d5b49f8c88ce007bf9a362fd.xlsx"
+        },
+        {
+            "title": "TableS3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/842bd0fc885c2cf28db9991c.xlsx"
+        },
+        {
+            "title": "TableS4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/5125eea0bbaaf99f06741075.xlsx"
+        },
+        {
+            "title": "TableS5.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/ffb2cbf301c813aa5a58eef6.xlsx"
+        },
+        {
+            "title": "TableS6.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/4e6a320d9cb43c94c6d00359.xlsx"
+        },
+        {
+            "title": "TableS7.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/64507a65958b18dbfe7b653b.docx"
+        },
+        {
+            "title": "TableS8.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3290264/v1/5a7341f0baa942137c927dbc.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/260429c99ce5084104d52cd9c018527d3936c44282318b70cd525c563fe65941/metadata.json b/260429c99ce5084104d52cd9c018527d3936c44282318b70cd525c563fe65941/metadata.json
index 1194ac30a3c8fdb8da85dce8f0401804315ca462..7ffdf3a5bc1526bb5d134606062216b4817056b1 100644
--- a/260429c99ce5084104d52cd9c018527d3936c44282318b70cd525c563fe65941/metadata.json
+++ b/260429c99ce5084104d52cd9c018527d3936c44282318b70cd525c563fe65941/metadata.json
@@ -205,5 +205,47 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "FigureS1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/14b947dd557d3084c9f575e8.pdf"
+        },
+        {
+            "title": "FigureS2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/2c21d481f25d12e1029dd174.pdf"
+        },
+        {
+            "title": "FigureS3.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/a0e60cbb8b5a4e102ee502c2.pdf"
+        },
+        {
+            "title": "FigureS4small.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/efffc46ced929fa86ff001b5.pdf"
+        },
+        {
+            "title": "FigureS5small.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/f3a1bf07e84092aa2fba6f57.pdf"
+        },
+        {
+            "title": "FigureS6.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/55f3d52317ea47d4ec5f6842.pdf"
+        },
+        {
+            "title": "FigureS7.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/8f592d544072475ee93ce6d4.pdf"
+        },
+        {
+            "title": "SupplementaryTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/7ef48373a025a91ddc8345b6.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/0f98d89f16b91ce2f84d2d64.xlsx"
+        },
+        {
+            "title": "KDBfusionsPTCLsupplementalrevisedfinal.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-200114/v1/34926cc50dbcb57adb3659a1.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/27924350800667e5e31983b869d13d00f23872a9c57e8f98e1999c224d2e7641/metadata.json b/27924350800667e5e31983b869d13d00f23872a9c57e8f98e1999c224d2e7641/metadata.json
index a4ad2aa3c4c76eb82730c11531bcebb23546ffd9..7aa06c45c599d2fcfc71818c0a23507f83d43c6e 100644
--- a/27924350800667e5e31983b869d13d00f23872a9c57e8f98e1999c224d2e7641/metadata.json
+++ b/27924350800667e5e31983b869d13d00f23872a9c57e8f98e1999c224d2e7641/metadata.json
@@ -188,5 +188,39 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendedDataFigurescombined14Mar2025.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/2b87b4b9a1584360b5b2bac2.pdf"
+        },
+        {
+            "title": "ExtendedDataTable1emmeansWWHvsWWoHavg.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/83afb5149e47f42a02f5db78.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable2emmeansWWHvsWWoHstrat.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/bdaaa0e46e635ada867a4a18.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable3correlationwithCD4andVL.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/63f8a6b2c32ecd9bc9eb19ef.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable4RFWWHvsWWoHbyVisit.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/4ca4606694b295eb2c5d249f.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable5emmeansHEUvsHUUavg.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/403e065fe7733e6996ac6677.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable6emmeansHEUvsHUUstrat.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/8a4059d09f264051c020dadf.xlsx"
+        },
+        {
+            "title": "ExtendedDataTables79GlobalandQuantKTValues.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6229815/v1/5e1e66e682b17a7144914546.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2a70f6fca42a0ab1796c07cdeb938f8e1fc2a923251322318ec8581d8ba6cdbf/metadata.json b/2a70f6fca42a0ab1796c07cdeb938f8e1fc2a923251322318ec8581d8ba6cdbf/metadata.json
index 0762ccf8824d1c47df08a7182be37585dc109402..2de673a6e6cd845cf37cb0075bd1109ea4159c8c 100644
--- a/2a70f6fca42a0ab1796c07cdeb938f8e1fc2a923251322318ec8581d8ba6cdbf/metadata.json
+++ b/2a70f6fca42a0ab1796c07cdeb938f8e1fc2a923251322318ec8581d8ba6cdbf/metadata.json
@@ -132,5 +132,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nCurrent Pollution Reports (2025)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "InventoryofSupportingInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1646168/v1/33a4813e5641924703664f9e.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2b0f6ea9e001b8d5fc2be38173edd65f51a0d7285b0182711c321e987e96610a/metadata.json b/2b0f6ea9e001b8d5fc2be38173edd65f51a0d7285b0182711c321e987e96610a/metadata.json
index abb7aa91ff68216b936e88b1df93ea732b1cde91..de91687805f7aef8469a87be730d288aebc23892 100644
--- a/2b0f6ea9e001b8d5fc2be38173edd65f51a0d7285b0182711c321e987e96610a/metadata.json
+++ b/2b0f6ea9e001b8d5fc2be38173edd65f51a0d7285b0182711c321e987e96610a/metadata.json
@@ -156,5 +156,15 @@
             "section_text": "Nature Communications (2025)\n\nDiscover Oncology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "nreditorialpolicychecklistNCOMMS2237312T.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2006961/v1/b8c6b6d93403e50e9f208896.pdf"
+        },
+        {
+            "title": "nrreportingsummaryNCOMMS2237312T.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2006961/v1/0f79d1ca63db3bf38306fa85.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2ce052fe1d680afbe1af94fbea6482eee6a7adc9740ab863565b687cb664832d/metadata.json b/2ce052fe1d680afbe1af94fbea6482eee6a7adc9740ab863565b687cb664832d/metadata.json
index 8f23373c5cb61239ae47e2a12139c72274104fe9..f96dd2bf3eb6da80bf983fddbc7fbce459331607 100644
--- a/2ce052fe1d680afbe1af94fbea6482eee6a7adc9740ab863565b687cb664832d/metadata.json
+++ b/2ce052fe1d680afbe1af94fbea6482eee6a7adc9740ab863565b687cb664832d/metadata.json
@@ -198,5 +198,43 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MaireetalSupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/328528de780bb306dccb6430.pdf"
+        },
+        {
+            "title": "SupplementaryTable1Maire.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/3c65188d1e56cb4a779f79a9.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2Maire.xls",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/56c0a534163cce3363d929e1.xls"
+        },
+        {
+            "title": "SupplementaryTable4Maire.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/507f624e4ac4c009ac64ff3a.xlsx"
+        },
+        {
+            "title": "SupplementaryVideo1ctrl.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/a8c8143fd098ce6c0639b329.mp4"
+        },
+        {
+            "title": "SupplementaryVideo2ASB2cKO.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/730b56800242ec1ddc4208be.mp4"
+        },
+        {
+            "title": "SupplementaryVideo3DMSOtreated.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/3b7b23cf58611ed75a7fdb8a.mp4"
+        },
+        {
+            "title": "SupplementaryVideo4TSTtreated.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/c85da5ee8bf67b049542a566.mp4"
+        },
+        {
+            "title": "NCOMMS2402393rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3878460/v1/703b162ac47729d3950ae809.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2d5602b748e28373dfb643917ba2dfb3979664627ec3a7d67bbe00aa954dee2e/metadata.json b/2d5602b748e28373dfb643917ba2dfb3979664627ec3a7d67bbe00aa954dee2e/metadata.json
index b22a956d0209c1be95f886cd1926bb3e0e2aa87e..bb10c0313cc7ce5e25b50d2520dde29cde4544ec 100644
--- a/2d5602b748e28373dfb643917ba2dfb3979664627ec3a7d67bbe00aa954dee2e/metadata.json
+++ b/2d5602b748e28373dfb643917ba2dfb3979664627ec3a7d67bbe00aa954dee2e/metadata.json
@@ -173,5 +173,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplTable1HypoxiaWTvsHIF1aKO.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3830704/v1/5e89fe5b927cf1087d839405.xlsx"
+        },
+        {
+            "title": "SupplTable2NormoxiaWTvsHIF1aKO.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3830704/v1/1276112b1b82941d20d8281b.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/2de9a4fc82ff994dd8672bfaa8e66e4ab1f28f221d38c871996f5d667af37fd8/metadata.json b/2de9a4fc82ff994dd8672bfaa8e66e4ab1f28f221d38c871996f5d667af37fd8/metadata.json
index 317d150f53313466b6236212e3fd4ec969403e45..4910e4e3d7df8cd8b0dad31d5126024ef990acc5 100644
--- a/2de9a4fc82ff994dd8672bfaa8e66e4ab1f28f221d38c871996f5d667af37fd8/metadata.json
+++ b/2de9a4fc82ff994dd8672bfaa8e66e4ab1f28f221d38c871996f5d667af37fd8/metadata.json
@@ -163,5 +163,23 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementarytableStatisticsandnnumbers.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5047146/v1/f813788931e9c162eb76e681.pdf"
+        },
+        {
+            "title": "Supplementaryvideo1OptogeneticactivationofPVaxons.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5047146/v1/cf6980167720e5b34cb2d305.mp4"
+        },
+        {
+            "title": "Supplementaryvideo2DBSeffectofmicewithPVcellablation.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5047146/v1/85630fad9835315e28aa8204.mp4"
+        },
+        {
+            "title": "Supplementaryvideo3OptogeneticstimulationofSyt1KDPVaxons.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5047146/v1/c329fef4754dac53492646ba.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3178cef45b8f6224ac0bd57318c086e2d578a6c84b0379c7f84eeeb3862d93e2/metadata.json b/3178cef45b8f6224ac0bd57318c086e2d578a6c84b0379c7f84eeeb3862d93e2/metadata.json
index 923495518f48e336958824af509361d381858c7e..31394d807b1bde8663cfc18c9e50e8e6c7238b74 100644
--- a/3178cef45b8f6224ac0bd57318c086e2d578a6c84b0379c7f84eeeb3862d93e2/metadata.json
+++ b/3178cef45b8f6224ac0bd57318c086e2d578a6c84b0379c7f84eeeb3862d93e2/metadata.json
@@ -213,5 +213,19 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Guelfoetal.MaterialsandMethods.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3150504/v1/7e4c580f47177ef43624ec00.docx"
+        },
+        {
+            "title": "Guelfoetal.DataS1S7.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3150504/v1/a3b57bf1017b057581af2247.xlsx"
+        },
+        {
+            "title": "Guelfoetal.SupplementaryMaterial.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3150504/v1/80bbf32a347e8b80f35d6cde.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/34a06a85a426767e87cb3ef1826a9a91b94ab12100349007e92f54a0b900d1dd/metadata.json b/34a06a85a426767e87cb3ef1826a9a91b94ab12100349007e92f54a0b900d1dd/metadata.json
index d04da586c45e7a1464ff9dc6ae9a7a61ca862cc6..b60f8a0aed8e774475b51f1d5e1e9ad1b1f370c0 100644
--- a/34a06a85a426767e87cb3ef1826a9a91b94ab12100349007e92f54a0b900d1dd/metadata.json
+++ b/34a06a85a426767e87cb3ef1826a9a91b94ab12100349007e92f54a0b900d1dd/metadata.json
@@ -157,5 +157,19 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementarymaterialIRISKpRR.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4582961/v1/218df94479aae53624210464.pdf"
+        },
+        {
+            "title": "supplementarytablesIRISKpRR.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4582961/v1/16ae0164e773eb1e7f8030b8.xlsx"
+        },
+        {
+            "title": "NCOMMS2417508ARS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4582961/v1/b4dba63e85fcdae4cb33dcd9.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/35e23d15b5cd6a6464eae0671a445daff29d5876d370babb087465ffd8c10d42/metadata.json b/35e23d15b5cd6a6464eae0671a445daff29d5876d370babb087465ffd8c10d42/metadata.json
index 1bf8da544e623b58817850bec642ba44aa6b73d4..612ea61bdcd2bec5ff66c52f5d748e4910abc70c 100644
--- a/35e23d15b5cd6a6464eae0671a445daff29d5876d370babb087465ffd8c10d42/metadata.json
+++ b/35e23d15b5cd6a6464eae0671a445daff29d5876d370babb087465ffd8c10d42/metadata.json
@@ -163,5 +163,15 @@
             "section_text": "Experimental & Molecular Medicine (2025)\n\nNature Reviews Molecular Cell Biology (2025)\n\nNature Communications (2025)\n\nStem Cell Research & Therapy (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "dmIRSUPPLEMENTARYINFORMATION20022023.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2607894/v1/7296e008b7d32ed421418753.pdf"
+        },
+        {
+            "title": "nrreportingsummaryNCOMMS2307694AMBrzozowskiFlattened.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2607894/v1/d92e3152249377a78cb0a532.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3666774aaa9006a7fa601b37f1ab0a814895e59d243272164e6bd436e31523a6/metadata.json b/3666774aaa9006a7fa601b37f1ab0a814895e59d243272164e6bd436e31523a6/metadata.json
index 20d7be3c68711c532139b9dc435a161cc9ce6714..bfa13394f5f10864500c8bbe5a7d6b6547a31a37 100644
--- a/3666774aaa9006a7fa601b37f1ab0a814895e59d243272164e6bd436e31523a6/metadata.json
+++ b/3666774aaa9006a7fa601b37f1ab0a814895e59d243272164e6bd436e31523a6/metadata.json
@@ -210,5 +210,19 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MovieS1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-468739/v1/8d1f74387cd6921777321602.mp4"
+        },
+        {
+            "title": "MovieS2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-468739/v1/06ef5cc42d0e7fe263cb1a85.mp4"
+        },
+        {
+            "title": "SupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-468739/v1/925ccc3f71dfbb01eb0d2ecd.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/374c80a1127a3167a1259abdbf7433b94b859983f3b989ac957bcc284d13860b/metadata.json b/374c80a1127a3167a1259abdbf7433b94b859983f3b989ac957bcc284d13860b/metadata.json
index 7c286e65bef5f5cab5611e06695c8b35d43cb6a4..ef47480b26528e83b0edfb8b2c505cd53e1ed4f4 100644
--- a/374c80a1127a3167a1259abdbf7433b94b859983f3b989ac957bcc284d13860b/metadata.json
+++ b/374c80a1127a3167a1259abdbf7433b94b859983f3b989ac957bcc284d13860b/metadata.json
@@ -196,5 +196,27 @@
             "section_text": "BMC Bioinformatics (2025)\n\nBMC Bioinformatics (2025)\n\nScientific Reports (2025)\n\nNature Protocols (2025)\n\nNature Methods (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "nrsoftwarepolicy0908.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2049486/v1/a3bc0a5b59e05d5309264cfd.pdf"
+        },
+        {
+            "title": "nreditorialpolicychecklist0908.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2049486/v1/374c6f057173f380915118ad.pdf"
+        },
+        {
+            "title": "nrreportingsummary0908.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2049486/v1/07a91b31eda64b9a15df16c9.pdf"
+        },
+        {
+            "title": "w2rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2049486/v1/fe6d577112be9f5976a62eeb.pdf"
+        },
+        {
+            "title": "w3code.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2049486/v1/411d6bfeb799477c47c967b6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/397452e1ee14ed5f22812b8e1da6824d4b9b33f94318ceb1dbb6a09dbe89e4c8/metadata.json b/397452e1ee14ed5f22812b8e1da6824d4b9b33f94318ceb1dbb6a09dbe89e4c8/metadata.json
index 61e4e2abb2c8e7dead1402cc4a07b0fa44369a68..ce85143c8f97089dca68ff6a5f576f347c4558fa 100644
--- a/397452e1ee14ed5f22812b8e1da6824d4b9b33f94318ceb1dbb6a09dbe89e4c8/metadata.json
+++ b/397452e1ee14ed5f22812b8e1da6824d4b9b33f94318ceb1dbb6a09dbe89e4c8/metadata.json
@@ -163,5 +163,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryMaterialsOutofsightoutofmindCostofminimizingvisibilityofnationwiderenewableenergysystems.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5017073/v1/e4df9cea4d5fce0c0e0548c6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3a66655d37e36bfe7dda338793f235e4e95053956515eb09ae148574738ab612/metadata.json b/3a66655d37e36bfe7dda338793f235e4e95053956515eb09ae148574738ab612/metadata.json
index fd2ecce65bbdea5fe9b3cca6e2d17b2dbc41dc70..9b95cd0852db60f692fcd33fb00d5580a9759f00 100644
--- a/3a66655d37e36bfe7dda338793f235e4e95053956515eb09ae148574738ab612/metadata.json
+++ b/3a66655d37e36bfe7dda338793f235e4e95053956515eb09ae148574738ab612/metadata.json
@@ -209,5 +209,43 @@
             "section_text": "Molecular Cancer (2025)\n\nNature Communications (2025)\n\nNature Biotechnology (2025)\n\nNature Reviews Genetics (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "20221102SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/ba858de712bbc29a73e58ff5.pdf"
+        },
+        {
+            "title": "TableS1.E135wilcoxallDEGsforallspatialdomains.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/83fd0fb4d6d748fd8a61c426.csv"
+        },
+        {
+            "title": "TableS2.E135regulonRSSforallspatialdomains.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/466c992c696b7faf9aa97b07.csv"
+        },
+        {
+            "title": "TableS3.E135visceralorgansubclusterswilcoxmarkers.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/b3593d3a8852c52d69a0f2a1.csv"
+        },
+        {
+            "title": "TableS4.E135visceralorgansubclusterregulonrsstop5.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/6630720c0bcdf7be14d6b464.csv"
+        },
+        {
+            "title": "TableS5.E135spinalcordAPDEGtopgenes.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/809371dc334c3ec548024181.csv"
+        },
+        {
+            "title": "TableS6.E135DorsalMedialVentralDEGs.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/91fe8839ed985452e8a15c0a.csv"
+        },
+        {
+            "title": "TableS7.E135STSCdeconvultionbyRCTDallweightsconf.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/ed3d19367ba1b909490d10fd.csv"
+        },
+        {
+            "title": "TableS8.E135STcommresults.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2230279/v1/68cff8048e5def14867c4f67.csv"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3a8779812493791762eaae2fa18b44a05cbe747996aeb29ef061c778922d6331/metadata.json b/3a8779812493791762eaae2fa18b44a05cbe747996aeb29ef061c778922d6331/metadata.json
index 3306449fe9df8fe76c1c975754cd5310bd833a21..c52eb7d262021a96229b6635ada99484c4338562 100644
--- a/3a8779812493791762eaae2fa18b44a05cbe747996aeb29ef061c778922d6331/metadata.json
+++ b/3a8779812493791762eaae2fa18b44a05cbe747996aeb29ef061c778922d6331/metadata.json
@@ -141,5 +141,11 @@
             "section_text": "Nature Communications (2025)\n\nnpj Computational Materials (2025)\n\nNature Communications (2024)\n\nNature Materials (2023)\n\nNature Communications (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SInew.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1199006/v1/5c320c4911cc85228f8a7274.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3bfe8562b7f491e8a7e27faa44870885872f1e420ab4e8b487231927aa575f7e/metadata.json b/3bfe8562b7f491e8a7e27faa44870885872f1e420ab4e8b487231927aa575f7e/metadata.json
index c9b5d09752aeb9a228812d014981eec235bae3ae..b6aecfcb8cb29a78f15d6f5b571846c848db8e3b 100644
--- a/3bfe8562b7f491e8a7e27faa44870885872f1e420ab4e8b487231927aa575f7e/metadata.json
+++ b/3bfe8562b7f491e8a7e27faa44870885872f1e420ab4e8b487231927aa575f7e/metadata.json
@@ -167,5 +167,59 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "reportingSummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/b090ffb53f239ecfe33d9177.pdf"
+        },
+        {
+            "title": "7Y4XvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/c92d2c82b53326c4445e1161.pdf"
+        },
+        {
+            "title": "7Y54valreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/faaea621f7dcc3e530d92607.pdf"
+        },
+        {
+            "title": "7Y5JvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/daf6524da1c9f2f1ec1474d3.pdf"
+        },
+        {
+            "title": "7Y5RvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/820cbdbc4c793ccff1636ac2.pdf"
+        },
+        {
+            "title": "7Y6EvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/053c98647eb74c43a099ed38.pdf"
+        },
+        {
+            "title": "7Y6OvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/b6c8e9da2215a35cced08c86.pdf"
+        },
+        {
+            "title": "7Y73valreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/7b4f56254f082cdade85ae4a.pdf"
+        },
+        {
+            "title": "7Y8HvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/1c53285e044d5fe500109da1.pdf"
+        },
+        {
+            "title": "7Y8IvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/75673cb711fddcbbc917427f.pdf"
+        },
+        {
+            "title": "7Y8SvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/a81c430b30eeaefb0e1fc704.pdf"
+        },
+        {
+            "title": "7Y95valreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/273f47aa9a3e4291e3c006c7.pdf"
+        },
+        {
+            "title": "7Y9AvalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1973770/v1/139c1b2753c765d3f37fe704.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3c30fc18e852ee3aa258f2095bd0e59ef5e9263212e635a56b7a776499b09348/metadata.json b/3c30fc18e852ee3aa258f2095bd0e59ef5e9263212e635a56b7a776499b09348/metadata.json
index 5f11aa73c1cb92f34969e69ae983be3da8e08054..4178280b45ce905ef8edd71459cb7be9966d7d5a 100644
--- a/3c30fc18e852ee3aa258f2095bd0e59ef5e9263212e635a56b7a776499b09348/metadata.json
+++ b/3c30fc18e852ee3aa258f2095bd0e59ef5e9263212e635a56b7a776499b09348/metadata.json
@@ -181,5 +181,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4601714/v1/41c2882f7db51bc65b3aaae3.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3d66c399a2dbcfa2ece0132fa58c977bdb5645afd48433f18cd6dc1d49d0d239/metadata.json b/3d66c399a2dbcfa2ece0132fa58c977bdb5645afd48433f18cd6dc1d49d0d239/metadata.json
index 6224a6ccf0a245a2bbc033034f4b68a9d077dc5e..b3faf04ff69453db602f19b40e2921da877f4eee 100644
--- a/3d66c399a2dbcfa2ece0132fa58c977bdb5645afd48433f18cd6dc1d49d0d239/metadata.json
+++ b/3d66c399a2dbcfa2ece0132fa58c977bdb5645afd48433f18cd6dc1d49d0d239/metadata.json
@@ -166,5 +166,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "6.supplementarytable14.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3037031/v1/5c44b81ce41433ee3baf4b59.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3da6f7c1dbe65017857cce6485ddcabd264ffece0167ad76290b885845fabdf6/metadata.json b/3da6f7c1dbe65017857cce6485ddcabd264ffece0167ad76290b885845fabdf6/metadata.json
index 1b612ef143e8482626b08a899a41e0dde45eb881..b2f55cbdcd0705e2c88955f08c206a3bf4fde99e 100644
--- a/3da6f7c1dbe65017857cce6485ddcabd264ffece0167ad76290b885845fabdf6/metadata.json
+++ b/3da6f7c1dbe65017857cce6485ddcabd264ffece0167ad76290b885845fabdf6/metadata.json
@@ -261,5 +261,19 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplMovie.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3220888/v1/6bfdaa68be4d736d7c871fe0.mp4"
+        },
+        {
+            "title": "SupplementalDuering1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3220888/v1/9aec17e0301838cc32bab563.pdf"
+        },
+        {
+            "title": "ValidationHACE1RAC1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3220888/v1/d73357f546658fbcca911710.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/3e9c3359b0dbb9cebdc84cd7c3e91539ac216ffb4da3ccd80d3cfaacff69aa6e/metadata.json b/3e9c3359b0dbb9cebdc84cd7c3e91539ac216ffb4da3ccd80d3cfaacff69aa6e/metadata.json
index f8a485e0da9bd4869d2dba41e06108f23d55db6f..c86459ead954d65c1695fe6dc9ac42fb5bcfe480 100644
--- a/3e9c3359b0dbb9cebdc84cd7c3e91539ac216ffb4da3ccd80d3cfaacff69aa6e/metadata.json
+++ b/3e9c3359b0dbb9cebdc84cd7c3e91539ac216ffb4da3ccd80d3cfaacff69aa6e/metadata.json
@@ -157,5 +157,27 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nNature Communications (2025)\n\nNature Reviews Electrical Engineering (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinformation18.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1903675/v1/fec68adc83968252f2216384.pdf"
+        },
+        {
+            "title": "Video1Secondorderspatialdifferentiation2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1903675/v1/d96a6b52b501370193fd114f.mp4"
+        },
+        {
+            "title": "Video2Firstorderspatialdifferentiation2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1903675/v1/504254f89b08ac1d6a3e806e.mp4"
+        },
+        {
+            "title": "Video3Fourthorderspatialdifferentiation.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1903675/v1/9973f145f56e3e5b24750c2f.avi"
+        },
+        {
+            "title": "Video4Thirdorderspatialdifferentiation.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1903675/v1/acba28bd3cd3234498d13959.avi"
+        }
     ]
 }
\ No newline at end of file
diff --git a/411f68b0072d1982d41fa9ef4552289f25b219c2817e825365f72fd748f7b0cb/metadata.json b/411f68b0072d1982d41fa9ef4552289f25b219c2817e825365f72fd748f7b0cb/metadata.json
index 18957e4a2f001e586e79e2b079a857e1b7bf89bd..783ebbbff3717847a07d446ad8e0543a8c42a87c 100644
--- a/411f68b0072d1982d41fa9ef4552289f25b219c2817e825365f72fd748f7b0cb/metadata.json
+++ b/411f68b0072d1982d41fa9ef4552289f25b219c2817e825365f72fd748f7b0cb/metadata.json
@@ -166,5 +166,11 @@
             "section_text": "Iran Journal of Computer Science (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "HuaxuYumasscubesupplementaryinformation11252024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5530740/v1/dad5d5c4d8b5f9bd92b5de9c.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/413d403d33d701e2de74e57f7015922ff20ebbc6cdf3506db1f6078098c231e6/metadata.json b/413d403d33d701e2de74e57f7015922ff20ebbc6cdf3506db1f6078098c231e6/metadata.json
index cb43cae90d5e22eb6f57ff7e948bd90da4a64abc..236188853e9363af2f11a393dbd952b48005483f 100644
--- a/413d403d33d701e2de74e57f7015922ff20ebbc6cdf3506db1f6078098c231e6/metadata.json
+++ b/413d403d33d701e2de74e57f7015922ff20ebbc6cdf3506db1f6078098c231e6/metadata.json
@@ -170,5 +170,23 @@
             "section_text": "Nature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryinformationAbioinspiredtactilescannerforcomputerhaptics.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3863292/v1/a1ba4a25d8152652553ec674.pdf"
+        },
+        {
+            "title": "SupplementaryVideo1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3863292/v1/e23c78acf2a0abc48d4a29ad.mp4"
+        },
+        {
+            "title": "SupplementaryVideo2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3863292/v1/38aab4ce27eefe3fa4205230.mp4"
+        },
+        {
+            "title": "SupplementaryVideo3.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3863292/v1/104c4bcc17ae6a454e527c1f.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/42236cdce814b6f16452541b829274fa16205f7d595121945ec587de3c00c67c/metadata.json b/42236cdce814b6f16452541b829274fa16205f7d595121945ec587de3c00c67c/metadata.json
index 67a3e8e59414a53b7d0e4c3d149d02ab11adc880..7b02afe9c9489152467e41676a34decbed276b13 100644
--- a/42236cdce814b6f16452541b829274fa16205f7d595121945ec587de3c00c67c/metadata.json
+++ b/42236cdce814b6f16452541b829274fa16205f7d595121945ec587de3c00c67c/metadata.json
@@ -204,5 +204,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "multiprojection.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3118867/v1/70fd05f44e09e7bf4578d6bd.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4347ad13967a0fb2d71346bb2c587edc0d41f311204b855d620ba628a8cbde27/metadata.json b/4347ad13967a0fb2d71346bb2c587edc0d41f311204b855d620ba628a8cbde27/metadata.json
index e5d51842f7f633c5cd109c862509da880eec2b4a..0e0286710f41f62367a167c6c36284004960ca88 100644
--- a/4347ad13967a0fb2d71346bb2c587edc0d41f311204b855d620ba628a8cbde27/metadata.json
+++ b/4347ad13967a0fb2d71346bb2c587edc0d41f311204b855d620ba628a8cbde27/metadata.json
@@ -195,5 +195,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "EDMovie1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5073364/v1/26d7bf52472b0c25eac4247b.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/43f57920d0cc1b4b5cc7738208cf1e5082ada58cf4830c9ce4fa16eabc64f49e/metadata.json b/43f57920d0cc1b4b5cc7738208cf1e5082ada58cf4830c9ce4fa16eabc64f49e/metadata.json
index e2d1b2241648e7f54c168403aab0c0297f144726..a350ec15797a00025055d7fa4232411dc8352eb0 100644
--- a/43f57920d0cc1b4b5cc7738208cf1e5082ada58cf4830c9ce4fa16eabc64f49e/metadata.json
+++ b/43f57920d0cc1b4b5cc7738208cf1e5082ada58cf4830c9ce4fa16eabc64f49e/metadata.json
@@ -151,5 +151,11 @@
             "section_text": "Light: Science & Applications (2025)\n\nNature Communications (2025)\n\nScientific Reports (2025)\n\nInternational Journal of Computer Vision (2025)\n\nLight: Science & Applications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "dataandsupportingfiles.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-129598/v1/1eaa493b2b12460d9db7bf8a.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/441781baa1b2dedeba52491b135464cc88bacc38a173fe0d5b9f563ad3051d30/metadata.json b/441781baa1b2dedeba52491b135464cc88bacc38a173fe0d5b9f563ad3051d30/metadata.json
index c1b06de9d415cd7d4d8206e39727c0ecb24af59f..02e946bac6011a5bd9dbd5274f5ad89d6c67fa89 100644
--- a/441781baa1b2dedeba52491b135464cc88bacc38a173fe0d5b9f563ad3051d30/metadata.json
+++ b/441781baa1b2dedeba52491b135464cc88bacc38a173fe0d5b9f563ad3051d30/metadata.json
@@ -162,5 +162,15 @@
             "section_text": "Biotechnology for Biofuels and Bioproducts (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1809686/v1/b8bfcb124ca13225d13a4b5f.xlsx"
+        },
+        {
+            "title": "SupplementaryTableS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1809686/v1/07c1573c77b3911fe75c04cf.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/441f9407302393914095b7edc3ad47804b8a172b40d660d04f980b77da7e41d6/metadata.json b/441f9407302393914095b7edc3ad47804b8a172b40d660d04f980b77da7e41d6/metadata.json
index e13ed99137be6703a714f62206d903968c6a382a..1db10772ead5cb1ba6b58e0fb10d622c1e6edfc6 100644
--- a/441f9407302393914095b7edc3ad47804b8a172b40d660d04f980b77da7e41d6/metadata.json
+++ b/441f9407302393914095b7edc3ad47804b8a172b40d660d04f980b77da7e41d6/metadata.json
@@ -135,5 +135,11 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementalInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-885489/v1/4f8b9d3d35e2d7b13c2c1308.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/45396c5958b245233b6b2c31915a68bf2e0759229a7b1a5f4508fa98479cf166/metadata.json b/45396c5958b245233b6b2c31915a68bf2e0759229a7b1a5f4508fa98479cf166/metadata.json
index 895612e8653b46554506be7f13dc87c39e020978..3641cbcbb89fb26843dcec69ecf83eaee3d7d5f0 100644
--- a/45396c5958b245233b6b2c31915a68bf2e0759229a7b1a5f4508fa98479cf166/metadata.json
+++ b/45396c5958b245233b6b2c31915a68bf2e0759229a7b1a5f4508fa98479cf166/metadata.json
@@ -161,5 +161,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementarydata.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3312866/v1/585ac9469745d647a2073603.pdf"
+        },
+        {
+            "title": "movie3PCsuper2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3312866/v1/5b4139dbe0a53445fb26c3c9.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4581dc25f72e60dee12903d05362de1d6b78894117cff28f5b1da8e4e217deba/metadata.json b/4581dc25f72e60dee12903d05362de1d6b78894117cff28f5b1da8e4e217deba/metadata.json
index 277fe150549665234d8d9f5711cd66632a86827f..a3ceec63ebdaf20af9126e765ad4b72132e29524 100644
--- a/4581dc25f72e60dee12903d05362de1d6b78894117cff28f5b1da8e4e217deba/metadata.json
+++ b/4581dc25f72e60dee12903d05362de1d6b78894117cff28f5b1da8e4e217deba/metadata.json
@@ -171,5 +171,11 @@
             "section_text": "Nature Plants (2025)\n\nPhytopathology Research (2024)\n\nChemical and Biological Technologies in Agriculture (2024)\n\nNature Communications (2023)\n\nJournal of Plant Biology (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Fanetal.supplementalinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-365288/v1/a8442872cb32a3dd525d4674.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/45f74ca9709712e156fe6f899d732c207d96d2bd47f1119c60253d0e71a68fbb/metadata.json b/45f74ca9709712e156fe6f899d732c207d96d2bd47f1119c60253d0e71a68fbb/metadata.json
index 6943039b1d7dc0cbdfedf32cb70cbbcc05619c65..3c585f76209c790b6ec9ad008b49ad6f28a02691 100644
--- a/45f74ca9709712e156fe6f899d732c207d96d2bd47f1119c60253d0e71a68fbb/metadata.json
+++ b/45f74ca9709712e156fe6f899d732c207d96d2bd47f1119c60253d0e71a68fbb/metadata.json
@@ -158,5 +158,11 @@
             "section_text": "Cellular & Molecular Biology Letters (2025)\n\nLeukemia (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ARFNPM1SUPPLINFO110923RKAPEG.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3592059/v1/eb2d7a371bf90d13e4e4108d.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/46c123409754c654bca4fa07a7aa0a40165fe55a38c2eec2afc939d4848ef074/metadata.json b/46c123409754c654bca4fa07a7aa0a40165fe55a38c2eec2afc939d4848ef074/metadata.json
index 9a0ce947cad7b15db67fd4162627e0521504d8c8..1a2f64e6fe754a075f471c6607d0ae822b44273f 100644
--- a/46c123409754c654bca4fa07a7aa0a40165fe55a38c2eec2afc939d4848ef074/metadata.json
+++ b/46c123409754c654bca4fa07a7aa0a40165fe55a38c2eec2afc939d4848ef074/metadata.json
@@ -133,5 +133,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4964841/v1/96ed5c0d72beeb8c0d346bec.pdf"
+        },
+        {
+            "title": "WeaktransitionenhancementNCommsSIhighlighted.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4964841/v1/be378638baa4d6230cc2efdd.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/46f8225776634ac8d37f18dc2239d5e80c2d86fb9f163fa79002408b3beec78a/metadata.json b/46f8225776634ac8d37f18dc2239d5e80c2d86fb9f163fa79002408b3beec78a/metadata.json
index 4dc7872b734ebe1c4100c20655e4f34d0731c3cd..7f92433963460013a84cb5a49e9ce764d54aa796 100644
--- a/46f8225776634ac8d37f18dc2239d5e80c2d86fb9f163fa79002408b3beec78a/metadata.json
+++ b/46f8225776634ac8d37f18dc2239d5e80c2d86fb9f163fa79002408b3beec78a/metadata.json
@@ -124,5 +124,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "2024VeyratetalAPHESI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4508425/v1/f8a1211f5811806a41245af1.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/47ed76f73bd4fdabb270d5144335729ac54d53f99282c632c26d276655ed3abc/metadata.json b/47ed76f73bd4fdabb270d5144335729ac54d53f99282c632c26d276655ed3abc/metadata.json
index 1816508bebbde0c537b6b005c963c1926583dcb4..e280aa4318939abaefc9f383e5edc0119fc5d3a8 100644
--- a/47ed76f73bd4fdabb270d5144335729ac54d53f99282c632c26d276655ed3abc/metadata.json
+++ b/47ed76f73bd4fdabb270d5144335729ac54d53f99282c632c26d276655ed3abc/metadata.json
@@ -148,5 +148,11 @@
             "section_text": "Nature (2025)\n\nNature (2025)\n\nNature Reviews Neuroscience (2025)\n\nNature Communications (2024)\n\nNature Machine Intelligence (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SMPizaetal.hippocampusprimacyNatureneuroscience.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3231892/v1/af094e3d0b08038127fe1f66.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4819fa60e2ce209b34a157450ed28888546a35fcfa4cdfb7ed96c2ae1ed60b19/metadata.json b/4819fa60e2ce209b34a157450ed28888546a35fcfa4cdfb7ed96c2ae1ed60b19/metadata.json
index 98833ffc007074e820b56f6b8987cbd6d00c8d7b..a42603492d4ff49c3370abcd3c68b0907f5fe5f4 100644
--- a/4819fa60e2ce209b34a157450ed28888546a35fcfa4cdfb7ed96c2ae1ed60b19/metadata.json
+++ b/4819fa60e2ce209b34a157450ed28888546a35fcfa4cdfb7ed96c2ae1ed60b19/metadata.json
@@ -156,5 +156,15 @@
             "section_text": "Nature Physics (2025)\n\nNature Photonics (2025)\n\nNature Physics (2024)\n\nNature Photonics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2150760/v1/030ce41d09e3823c40601bf3.pdf"
+        },
+        {
+            "title": "S1MovieGainLoss.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2150760/v1/b0f3df32e40f6bd6182cdf40.avi"
+        }
     ]
 }
\ No newline at end of file
diff --git a/487268b60d60a57ddf72c596fba8ead5ff013eeab984aee8c25ad6580afe57e1/metadata.json b/487268b60d60a57ddf72c596fba8ead5ff013eeab984aee8c25ad6580afe57e1/metadata.json
index a6fad8411463bbbe48f4f9e0e875efb7447c8adc..f38758f83aaf1746d2d0c54ed54327d37f18111c 100644
--- a/487268b60d60a57ddf72c596fba8ead5ff013eeab984aee8c25ad6580afe57e1/metadata.json
+++ b/487268b60d60a57ddf72c596fba8ead5ff013eeab984aee8c25ad6580afe57e1/metadata.json
@@ -146,5 +146,15 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2025)\n\nLight: Science & Applications (2021)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "VideoS1.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-106483/v1/56d51a9760b25274cdc2934b.avi"
+        },
+        {
+            "title": "RevisedSupportingInformationMichaelStranoNatureNanotechnology.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-106483/v1/b758a34357eb5630ada23657.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/488dd5e7f45f267645d4ecafeb0063d839323925821422c8cf4a42428a5d1df4/metadata.json b/488dd5e7f45f267645d4ecafeb0063d839323925821422c8cf4a42428a5d1df4/metadata.json
index 1d7a3fd679ef8d3dcfee6acd34604690185dc2e4..b8df7ecd9461f4c9dc2df2cadf83c28f3b01acfd 100644
--- a/488dd5e7f45f267645d4ecafeb0063d839323925821422c8cf4a42428a5d1df4/metadata.json
+++ b/488dd5e7f45f267645d4ecafeb0063d839323925821422c8cf4a42428a5d1df4/metadata.json
@@ -164,5 +164,27 @@
             "section_text": "Polar Biology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1472581/v2/50eb4e317e0fc0c1fcb72647.pdf"
+        },
+        {
+            "title": "SIGuide.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1472581/v2/bea194ad00be8f1541511470.docx"
+        },
+        {
+            "title": "SupplementaryTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1472581/v2/67f7aff84cba04ab62b55609.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1472581/v2/2173b0a8ff9e09de3f29ca43.xlsx"
+        },
+        {
+            "title": "SupplementaryVideo1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1472581/v2/729f085c166c292e5453c8bf.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/498fd5c2917d09467144a0e7e2f07487cf520745f96cfa0378c448526a87f516/metadata.json b/498fd5c2917d09467144a0e7e2f07487cf520745f96cfa0378c448526a87f516/metadata.json
index e8da50dab11fffb3cc21ae9511503cdc9f8a8297..80bdd8f6dc1da8ee9214f4ffeed872e271e838e1 100644
--- a/498fd5c2917d09467144a0e7e2f07487cf520745f96cfa0378c448526a87f516/metadata.json
+++ b/498fd5c2917d09467144a0e7e2f07487cf520745f96cfa0378c448526a87f516/metadata.json
@@ -163,5 +163,11 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NMISI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1571398/v1/92ea22ccc94d44f5278649a5.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4997c403ccbdf63e34792b3427909377712af8591f37fed23a643d8e1d3c6575/metadata.json b/4997c403ccbdf63e34792b3427909377712af8591f37fed23a643d8e1d3c6575/metadata.json
index 3795026c99ccd9775bcb02c9db97264ce16e448d..45d8afa5ec70562fa2bb66c8d48c245013451777 100644
--- a/4997c403ccbdf63e34792b3427909377712af8591f37fed23a643d8e1d3c6575/metadata.json
+++ b/4997c403ccbdf63e34792b3427909377712af8591f37fed23a643d8e1d3c6575/metadata.json
@@ -139,5 +139,11 @@
             "section_text": "Plant and Soil (2025)\n\nJournal of Soil Science and Plant Nutrition (2025)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Chomeletal2022.Supmat.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1283195/v1/63999adb725d4bbf0cb01d87.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4a0d9ab801df4bc282768981f75bca37f9f1fed6c762c8d12980f643e4142502/metadata.json b/4a0d9ab801df4bc282768981f75bca37f9f1fed6c762c8d12980f643e4142502/metadata.json
index 6918175b48feb332672c2ef76297aa1924d3c2d3..eb5f88020f208312eae044bdce962a6648a7237d 100644
--- a/4a0d9ab801df4bc282768981f75bca37f9f1fed6c762c8d12980f643e4142502/metadata.json
+++ b/4a0d9ab801df4bc282768981f75bca37f9f1fed6c762c8d12980f643e4142502/metadata.json
@@ -154,5 +154,11 @@
             "section_text": "Collection\n\nFocus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "C7HSINaturecommunicationsdoubleblind20220404.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1521832/v1/7f53540d1dcced5de44b2734.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4ba9a92303b664366f73f0ae958a8568c2b488177b6ecf2f1e414337c58d6632/metadata.json b/4ba9a92303b664366f73f0ae958a8568c2b488177b6ecf2f1e414337c58d6632/metadata.json
index 0cdbe495ec444a929ad2cde06faaf28e83eaf1e9..3f55a3c96fb8dde24ff208e11055134953aa89ed 100644
--- a/4ba9a92303b664366f73f0ae958a8568c2b488177b6ecf2f1e414337c58d6632/metadata.json
+++ b/4ba9a92303b664366f73f0ae958a8568c2b488177b6ecf2f1e414337c58d6632/metadata.json
@@ -117,5 +117,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4682574/v1/1df66ae78448e31ae6a5f45d.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4bad99da6edb5275abb0dfb383ec12ab0d9aa5d140b700116c07d5b2e982d11a/metadata.json b/4bad99da6edb5275abb0dfb383ec12ab0d9aa5d140b700116c07d5b2e982d11a/metadata.json
index 127ba85336f897954b1cbcf73b0ac3a42353f88d..04a7d0b6cc937a7690dbb11356ff3948ba5b80c7 100644
--- a/4bad99da6edb5275abb0dfb383ec12ab0d9aa5d140b700116c07d5b2e982d11a/metadata.json
+++ b/4bad99da6edb5275abb0dfb383ec12ab0d9aa5d140b700116c07d5b2e982d11a/metadata.json
@@ -138,5 +138,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TanakaNakahatabioinspiredwatertreatmentNatCommSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3422705/v1/eb7e91167b1df7a6146f56be.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4d0b72b215f47540c00d43254f05ea5257370e936a593adc3a345a5e880b8cfb/metadata.json b/4d0b72b215f47540c00d43254f05ea5257370e936a593adc3a345a5e880b8cfb/metadata.json
index 2cd9d0af6b15888ddfa745a34bdfb801cee50324..809e4e1a9338d2330c084ed25c614e628506d52b 100644
--- a/4d0b72b215f47540c00d43254f05ea5257370e936a593adc3a345a5e880b8cfb/metadata.json
+++ b/4d0b72b215f47540c00d43254f05ea5257370e936a593adc3a345a5e880b8cfb/metadata.json
@@ -139,5 +139,11 @@
             "section_text": "Scientific Data (2025)\n\nScience China Earth Sciences (2025)\n\nnpj Climate and Atmospheric Science (2024)\n\nNature Ecology & Evolution (2024)\n\nEnvironmental and Ecological Statistics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-827869/v1/9e7d26e992b726ab00c53062.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4ec18687be9919fc1de5ae25a5e6560952e41f3a864533abe3fe3796f91dc08d/metadata.json b/4ec18687be9919fc1de5ae25a5e6560952e41f3a864533abe3fe3796f91dc08d/metadata.json
index 7aa6bedc4841ec5e67f7e1d3f02bdb7a65e77008..7e6d18379db3a78e36ddf3be2c29be01c2d6c0ad 100644
--- a/4ec18687be9919fc1de5ae25a5e6560952e41f3a864533abe3fe3796f91dc08d/metadata.json
+++ b/4ec18687be9919fc1de5ae25a5e6560952e41f3a864533abe3fe3796f91dc08d/metadata.json
@@ -198,5 +198,23 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MaterialsandMethods202257.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1643401/v1/bbfbabb2f1372104cfccfff7.docx"
+        },
+        {
+            "title": "rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1643401/v1/23e103761f309812bbc2880d.pdf"
+        },
+        {
+            "title": "nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1643401/v1/3cf800cecabc9eed36e2344a.pdf"
+        },
+        {
+            "title": "supplementarydata2022510VL.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1643401/v1/a7563ded6a65a41c6eae091f.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4f0865a5a1a5d9cf466a1234ca5120c90691e301d99f83a46db2e623c7e5fab0/metadata.json b/4f0865a5a1a5d9cf466a1234ca5120c90691e301d99f83a46db2e623c7e5fab0/metadata.json
index 3e404418dd4185f48b9af8e598e1dc64d10556ce..4ff625e9ed0f5ff08fb98f199846ba49cdbb46f4 100644
--- a/4f0865a5a1a5d9cf466a1234ca5120c90691e301d99f83a46db2e623c7e5fab0/metadata.json
+++ b/4f0865a5a1a5d9cf466a1234ca5120c90691e301d99f83a46db2e623c7e5fab0/metadata.json
@@ -184,5 +184,39 @@
             "section_text": "Nature Machine Intelligence (2024)\n\nScientific Reports (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ebbesenfroemkesupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/31fa568c279b0e150599c367.pdf"
+        },
+        {
+            "title": "flatNMETHA42579nrreportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/694085792dcc83d7f5084d9e.pdf"
+        },
+        {
+            "title": "flatNMETHA42579nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/18e24d4f8aa84bd8f298848a.pdf"
+        },
+        {
+            "title": "supplementaryvideo1pipeline.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/af43866e22f709dc4a280297.mp4"
+        },
+        {
+            "title": "supplementaryvideo2particles.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/9deb615678e555068ef23331.mp4"
+        },
+        {
+            "title": "supplementaryvideo3smoothing.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/720dca47fc6c4ff338a9bcf9.mp4"
+        },
+        {
+            "title": "supplementaryvideo4social.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/2eec339f79231ca19b90c499.mp4"
+        },
+        {
+            "title": "supplementaryvideo5MousePlayer.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954647/v1/465a907b9d18794d7916a85d.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/4ffb7662bd5443653eee4e5bd2bd42044e10cd6a630d0b46c0e4fa72d9f94e34/metadata.json b/4ffb7662bd5443653eee4e5bd2bd42044e10cd6a630d0b46c0e4fa72d9f94e34/metadata.json
index 7c656818720b4ba84efac38291c6b5ea397ad433..26f5c47ed6237af3819f8d1cf0b88fae88c16191 100644
--- a/4ffb7662bd5443653eee4e5bd2bd42044e10cd6a630d0b46c0e4fa72d9f94e34/metadata.json
+++ b/4ffb7662bd5443653eee4e5bd2bd42044e10cd6a630d0b46c0e4fa72d9f94e34/metadata.json
@@ -162,5 +162,23 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "reportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5474597/v1/ce26cf7949d653db82bf0b32.pdf"
+        },
+        {
+            "title": "nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5474597/v1/31bfcd7a14df431de225d72b.pdf"
+        },
+        {
+            "title": "nrsoftwarepolicy.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5474597/v1/1e4150ad1494f1059e783eae.pdf"
+        },
+        {
+            "title": "DOLPHINSupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5474597/v1/c7f7f8b9ec7f992b798ee23f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/528f1402da5b90d0d0bf8f6d055639a4daa2190e989f953c476d20512ef60e81/metadata.json b/528f1402da5b90d0d0bf8f6d055639a4daa2190e989f953c476d20512ef60e81/metadata.json
index 46b8b9354e45864904b4aa4db7e0b7d0b0be77e3..17db309560a54662446791dd3c23f433fcbb62e8 100644
--- a/528f1402da5b90d0d0bf8f6d055639a4daa2190e989f953c476d20512ef60e81/metadata.json
+++ b/528f1402da5b90d0d0bf8f6d055639a4daa2190e989f953c476d20512ef60e81/metadata.json
@@ -132,5 +132,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "StructuredbathnatureSupplementary20241027.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5340471/v1/da214120216aa6a36df183b0.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/52f59808cf36bfcd5723a4e217b98308818e0be65feb6b84cf7a7afae8ae2666/metadata.json b/52f59808cf36bfcd5723a4e217b98308818e0be65feb6b84cf7a7afae8ae2666/metadata.json
index e273524cf39524faf58a3591563cf4d15e294cda..9cb646906157334e470de04880f0c275f229e035 100644
--- a/52f59808cf36bfcd5723a4e217b98308818e0be65feb6b84cf7a7afae8ae2666/metadata.json
+++ b/52f59808cf36bfcd5723a4e217b98308818e0be65feb6b84cf7a7afae8ae2666/metadata.json
@@ -178,5 +178,11 @@
             "section_text": "Commenting on this article is now closed.\n\nGrant Castillou 5 June 2023, 16:04\n\nIt's becoming clear that with all the brain and consciousness theories out there, the proof will be in the pudding. By this I mean, can any particular theory be used to create a human adult level conscious machine. My bet is on the late Gerald Edelman's Extended Theory of Neuronal Group Selection. The lead group in robotics based on this theory is the Neurorobotics Lab at UC at Irvine.  Dr. Edelman distinguished between primary consciousness, which came first in evolution, and that humans share with other conscious animals, and higher order consciousness, which came to only humans with the acquisition of language.  A machine with primary consciousness will probably have to come first.\n\nWhat I find special about the TNGS is the Darwin series of automata created at the Neurosciences Institute by Dr. Edelman and his colleagues in the 1990's and 2000's.  These machines perform in the real world, not in a restricted simulated world, and display convincing physical behavior indicative of higher psychological functions necessary for consciousness, such as perceptual categorization, memory, and learning.  They are based on realistic models of the parts of the biological brain that the theory claims subserve these functions.  The extended TNGS allows for the emergence of consciousness based only on further evolutionary development of the brain areas responsible for these functions, in a parsimonious way.  No other research I've encountered is anywhere near as convincing.\n\n I post because on almost every video and article about the brain and consciousness that I encounter,  the attitude seems to be that we still know next to nothing about how the brain and consciousness work; that there's lots of data but no unifying theory.  I believe the extended TNGS  is that theory.  My motivation is to keep that theory in front of the public.  And obviously, I consider it the route to a truly conscious machine, primary and higher-order.\n\nMy advice to people who want to create a conscious machine is to seriously ground themselves in the extended TNGS and the Darwin automata first, and proceed from there, by applying to Jeff Krichmar's lab at UC Irvine, possibly. Dr. Edelman's roadmap to a conscious machine is at https://arxiv.org/abs/2105....",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1750692/v1/d6459385ce7925162797dba9.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/55bb50661f85cad20a33e183bbf6373ddd12c2e99f749bafc1f51a628b8f15e9/metadata.json b/55bb50661f85cad20a33e183bbf6373ddd12c2e99f749bafc1f51a628b8f15e9/metadata.json
index 7cb7b3bc52fd373680d52859f9743c9951f5212c..e2439548d8414d80ab8254ab9ea49ce67b9d5a61 100644
--- a/55bb50661f85cad20a33e183bbf6373ddd12c2e99f749bafc1f51a628b8f15e9/metadata.json
+++ b/55bb50661f85cad20a33e183bbf6373ddd12c2e99f749bafc1f51a628b8f15e9/metadata.json
@@ -136,5 +136,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "futurepredictionNatureSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4907904/v1/08e7fada8d01d7ebc3295820.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5c7a7e6fa558bcbe95ddc94963783dd8a908e824ba4837e281c100a02ec57caf/metadata.json b/5c7a7e6fa558bcbe95ddc94963783dd8a908e824ba4837e281c100a02ec57caf/metadata.json
index 72948cafaf98ee7b934f81d60129dccea01c30bc..4927bbee3bb35b77650016d54773f80ae81d403a 100644
--- a/5c7a7e6fa558bcbe95ddc94963783dd8a908e824ba4837e281c100a02ec57caf/metadata.json
+++ b/5c7a7e6fa558bcbe95ddc94963783dd8a908e824ba4837e281c100a02ec57caf/metadata.json
@@ -156,5 +156,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Shenetalsupplfile.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5454185/v1/aa1fc4f6661d1bc4c8e29ace.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5cb48c1794aa7102546fbac0331ac16f269ac0ae1b5e0430e37fcfaec1c23f0b/metadata.json b/5cb48c1794aa7102546fbac0331ac16f269ac0ae1b5e0430e37fcfaec1c23f0b/metadata.json
index 4cdc43ca272d9754e179faa4af0dea01bc592442..9a5ec6516a57f6e1f1da519bbf69594d0985ce4c 100644
--- a/5cb48c1794aa7102546fbac0331ac16f269ac0ae1b5e0430e37fcfaec1c23f0b/metadata.json
+++ b/5cb48c1794aa7102546fbac0331ac16f269ac0ae1b5e0430e37fcfaec1c23f0b/metadata.json
@@ -185,5 +185,27 @@
             "section_text": "Nature Reviews Nephrology (2025)\n\nScience China Information Sciences (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable1druglikecandidatesforSCLC.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3917469/v1/559a92021e28c49fae104128.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2activecandidatesforSCLC.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3917469/v1/7b43d452f40346c5f85f26ba.xlsx"
+        },
+        {
+            "title": "SupplementaryTable3cellinfo.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3917469/v1/4cf5db07813cbbcf041a78f3.csv"
+        },
+        {
+            "title": "SupplementaryTable4drugesalldiseases.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3917469/v1/a02a012d0f31e1e75bdac80d.csv"
+        },
+        {
+            "title": "ExtendedData.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3917469/v1/4205e857b37ecffe57ccee00.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5da9293fd3a72c09288dc9f4aeed70ea54061794aa7804355dda5f96a262956b/metadata.json b/5da9293fd3a72c09288dc9f4aeed70ea54061794aa7804355dda5f96a262956b/metadata.json
index cdb266c08c16bc0967dd81211a99fc2479a7cc68..8ebdc7c605feadb77701f6493a8da3f814ca664f 100644
--- a/5da9293fd3a72c09288dc9f4aeed70ea54061794aa7804355dda5f96a262956b/metadata.json
+++ b/5da9293fd3a72c09288dc9f4aeed70ea54061794aa7804355dda5f96a262956b/metadata.json
@@ -189,5 +189,11 @@
             "section_text": "npj Vaccines (2025)\n\nNature Communications (2025)\n\nnpj Vaccines (2024)\n\nNature Medicine (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementsbooster.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1915346/v1/99ad4045fa802174844c9e09.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5dab773c2d86c7970d5e7d08c1de367d4809dd16d304da120bcfe752642ee7e4/metadata.json b/5dab773c2d86c7970d5e7d08c1de367d4809dd16d304da120bcfe752642ee7e4/metadata.json
index 75d8ccf5129aa49086f4f8cd8726ad59a90a413e..23d9effb758d3024c411aab453d51dc86c8e0439 100644
--- a/5dab773c2d86c7970d5e7d08c1de367d4809dd16d304da120bcfe752642ee7e4/metadata.json
+++ b/5dab773c2d86c7970d5e7d08c1de367d4809dd16d304da120bcfe752642ee7e4/metadata.json
@@ -152,5 +152,15 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "biologicalsupplementary07272023.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3211233/v1/e9693e6c2eca4a0b26963cf0.pdf"
+        },
+        {
+            "title": "RayBNN.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3211233/v1/6ff371e13a3d06dd30844a98.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5dec1ba46730b365d759603d1d2116f86a4a1a735326e292f5bb2c0479c504d1/metadata.json b/5dec1ba46730b365d759603d1d2116f86a4a1a735326e292f5bb2c0479c504d1/metadata.json
index d6a86518bd455c5aa7e036976fabcaa6fd0e18db..b7022c00a6eff06ce376e25e3da07430d118902a 100644
--- a/5dec1ba46730b365d759603d1d2116f86a4a1a735326e292f5bb2c0479c504d1/metadata.json
+++ b/5dec1ba46730b365d759603d1d2116f86a4a1a735326e292f5bb2c0479c504d1/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Computational Science (2025)\n\nNature Computational Science (2025)\n\nCommunications Physics (2025)\n\nNature Computational Science (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementSolid.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1689060/v1/1915312ea53061c900713897.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/5eba29ccae1c95aac940e6fa6003a1704f9e240a9a5c259b2b0e0e35866782ef/metadata.json b/5eba29ccae1c95aac940e6fa6003a1704f9e240a9a5c259b2b0e0e35866782ef/metadata.json
index 6ce0e44d0ff8e59a0b514e976439680c50e1485b..29fcec01aa3b605e415679c7fbd64cad0d725c62 100644
--- a/5eba29ccae1c95aac940e6fa6003a1704f9e240a9a5c259b2b0e0e35866782ef/metadata.json
+++ b/5eba29ccae1c95aac940e6fa6003a1704f9e240a9a5c259b2b0e0e35866782ef/metadata.json
@@ -162,5 +162,39 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformationJW.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/326d4929960ef24a8c6ce4f0.pdf"
+        },
+        {
+            "title": "ExtendedFiguresJW.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/012432feb20dfccd9d22d926.pdf"
+        },
+        {
+            "title": "ExtendedDataFigureandTablelegends.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/b24ab9bce5fd186e94f09322.pdf"
+        },
+        {
+            "title": "ExtendedDataTable1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/94fa70f728e74bb2c24128d5.pdf"
+        },
+        {
+            "title": "ExtendedDataTable2.xls",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/88529f9de6659e3cc06be09b.xls"
+        },
+        {
+            "title": "ExtendedDataTable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/667d5c3265395c8a4bf5eceb.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/c28ab1ab55cdc5a690a2fd2e.xlsx"
+        },
+        {
+            "title": "ExtendedDataTable5.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3353279/v1/a06a2cdb6b9f0653bbc8f581.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/6084efd8ba53e69bcae5bcfdbb304768b0af220b395281bb2cb8036f1f63a3df/metadata.json b/6084efd8ba53e69bcae5bcfdbb304768b0af220b395281bb2cb8036f1f63a3df/metadata.json
index c2e0ce188535a2c50d541399ef5ec47686957a92..d227f64e125a94bd264589d18798a6fdc5e82d1c 100644
--- a/6084efd8ba53e69bcae5bcfdbb304768b0af220b395281bb2cb8036f1f63a3df/metadata.json
+++ b/6084efd8ba53e69bcae5bcfdbb304768b0af220b395281bb2cb8036f1f63a3df/metadata.json
@@ -190,5 +190,23 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-120813/v1/43fd10f9b5d50b2cbbad5211.pdf"
+        },
+        {
+            "title": "Supplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-120813/v1/ada25d3083a36faca49e6ecf.pdf"
+        },
+        {
+            "title": "SupplementaryTableS6.S7.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-120813/v1/55e6132044235f040cdc96d5.xlsx"
+        },
+        {
+            "title": "SupplementaryTableS6.S7.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-120813/v1/0ab09ae4f8904a42187b9492.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/6085cf9f61a58dfec0d524e1ae64a8601a8d85815201512dbff5da80fe3e74a5/metadata.json b/6085cf9f61a58dfec0d524e1ae64a8601a8d85815201512dbff5da80fe3e74a5/metadata.json
index e59024e0097a0bb51d33f3af86079d379cebc32f..307a4c016aa4f2409217f53da4769837d24c0487 100644
--- a/6085cf9f61a58dfec0d524e1ae64a8601a8d85815201512dbff5da80fe3e74a5/metadata.json
+++ b/6085cf9f61a58dfec0d524e1ae64a8601a8d85815201512dbff5da80fe3e74a5/metadata.json
@@ -150,5 +150,11 @@
             "section_text": "Nature Communications (2025)\n\nBMC Infectious Diseases (2024)\n\nBMC Public Health (2024)\n\nCommunications Medicine (2024)\n\nJournal of Biosciences (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1199296/v1/d2b19c47bc23564b081d566b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/60d237eeef8c8371a1c03e5c06f12dccf8853eab463ca0a9b862cc6b1ba6fec8/metadata.json b/60d237eeef8c8371a1c03e5c06f12dccf8853eab463ca0a9b862cc6b1ba6fec8/metadata.json
index bf1810d925d14e2dd6efe802c2db7f27a49f6113..170376e18612c7176b89978d85323ae9512cce0a 100644
--- a/60d237eeef8c8371a1c03e5c06f12dccf8853eab463ca0a9b862cc6b1ba6fec8/metadata.json
+++ b/60d237eeef8c8371a1c03e5c06f12dccf8853eab463ca0a9b862cc6b1ba6fec8/metadata.json
@@ -164,5 +164,27 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementTablesS4.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3684698/v1/eb2db14b04ddef8703d9cf16.pdf"
+        },
+        {
+            "title": "SupplementTablesS5.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3684698/v1/b4e1f7bc92bc23588db4dfe3.pdf"
+        },
+        {
+            "title": "SupplementTablesS6.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3684698/v1/b436c4311adbbc04f9eebba0.pdf"
+        },
+        {
+            "title": "SupplementTablesS7.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3684698/v1/8cede5b8f306ffef2b4fb234.pdf"
+        },
+        {
+            "title": "Supplementsfinal.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3684698/v1/3c5c1d6c4cb2242fe8b655b0.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/63259967b4232ad20aa198a2b23eef28a8928bb707c1bdf35d22f48c35ff4639/metadata.json b/63259967b4232ad20aa198a2b23eef28a8928bb707c1bdf35d22f48c35ff4639/metadata.json
index 35ecdac9e22eb07d7be1f9384d89a123a14be869..2694974bb1a929b6cb5eb827e4366b9a1242a88a 100644
--- a/63259967b4232ad20aa198a2b23eef28a8928bb707c1bdf35d22f48c35ff4639/metadata.json
+++ b/63259967b4232ad20aa198a2b23eef28a8928bb707c1bdf35d22f48c35ff4639/metadata.json
@@ -183,5 +183,15 @@
             "section_text": "Nature Communications (2025)\n\nScience China Physics, Mechanics & Astronomy (2025)\n\nJournal of Fluorescence (2024)\n\nCell Research (2023)\n\nNature Chemical Biology (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "wholenew20210522.mp4.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-557882/v1/318c4424b51d6b2a88c30b57.mp4"
+        },
+        {
+            "title": "SI0524.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-557882/v1/757b5a216a6b46363b60f7a4.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/673ec8ca276487d8211d31a98e125436ec8c367659db23e38051469ea8afb398/metadata.json b/673ec8ca276487d8211d31a98e125436ec8c367659db23e38051469ea8afb398/metadata.json
index 3bdd230b84f93d7f6322ad42e284353c39bb139c..8cd6de740b608a86b08b6ee716fde7fa58b00e04 100644
--- a/673ec8ca276487d8211d31a98e125436ec8c367659db23e38051469ea8afb398/metadata.json
+++ b/673ec8ca276487d8211d31a98e125436ec8c367659db23e38051469ea8afb398/metadata.json
@@ -176,5 +176,15 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Mello062624Supplement.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4651047/v1/b8e78c299e65dce9d3b0d92a.docx"
+        },
+        {
+            "title": "rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4651047/v1/dda8c16cd001a2bfa68150ed.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/6955ed49395055def9d5302d40377996f54800076c1d46e1ea81c3ed680ea9dd/metadata.json b/6955ed49395055def9d5302d40377996f54800076c1d46e1ea81c3ed680ea9dd/metadata.json
index 20276c71d9039fc19148fe6ed959b64cb0daaf0f..a34e39929b752105c0192f005af48ced3b921e69 100644
--- a/6955ed49395055def9d5302d40377996f54800076c1d46e1ea81c3ed680ea9dd/metadata.json
+++ b/6955ed49395055def9d5302d40377996f54800076c1d46e1ea81c3ed680ea9dd/metadata.json
@@ -131,5 +131,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIEXAFSdetails.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3876546/v1/12161e3b2bfff4548d404fd7.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/6e810f38300811758ab7eab9b6c03a87ff1dde2eb852213e3e151c27fbcdf8e5/metadata.json b/6e810f38300811758ab7eab9b6c03a87ff1dde2eb852213e3e151c27fbcdf8e5/metadata.json
index 4259d4770cffbb77c62a5ab5d17772f1897782c7..c12ded1ac9041d22ddd5080e70761136290cc483 100644
--- a/6e810f38300811758ab7eab9b6c03a87ff1dde2eb852213e3e151c27fbcdf8e5/metadata.json
+++ b/6e810f38300811758ab7eab9b6c03a87ff1dde2eb852213e3e151c27fbcdf8e5/metadata.json
@@ -132,5 +132,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "reportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4357677/v1/c06745b61080909860584ca5.pdf"
+        },
+        {
+            "title": "SIR3.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4357677/v1/075bae18a8c28fd997c248a6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/70ee43a6d3657e1336ab71ffaf303dc14502adcee35398a0e24cc96929b64e52/metadata.json b/70ee43a6d3657e1336ab71ffaf303dc14502adcee35398a0e24cc96929b64e52/metadata.json
index b68a37550aa27d43699c08c06968fc29ed3782d3..b4fcc7854ee8f7b07ba85b24d47c88853855a84f 100644
--- a/70ee43a6d3657e1336ab71ffaf303dc14502adcee35398a0e24cc96929b64e52/metadata.json
+++ b/70ee43a6d3657e1336ab71ffaf303dc14502adcee35398a0e24cc96929b64e52/metadata.json
@@ -289,5 +289,35 @@
             "section_text": "Virology Journal (2025)\n\nEpigenetics & Chromatin (2025)\n\nCellular and Molecular Life Sciences (2025)\n\nNature Communications (2025)\n\nVeterinary Research (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable1ONTsequencingstats.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/d214618378fea33e0fe7690f.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2Transcriptssplicingjunctionscounts.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/01b7249232181635c51d587e.xlsx"
+        },
+        {
+            "title": "SupplementaryTable3Machinelearningmodelfeaturesandtrainingresults.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/b2fde65a5858931589f1efb9.xlsx"
+        },
+        {
+            "title": "SupplementaryTable4ONTsequencingdatalist.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/1d86e516e7e50d1fdb0306a9.xlsx"
+        },
+        {
+            "title": "SupplementaryTable5Primerlist.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/7c78f487a1be061413a7eb62.xlsx"
+        },
+        {
+            "title": "ExtendedDataFigures.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/22e5c87b0f5bc4d1a731c886.docx"
+        },
+        {
+            "title": "BaeketalHIVEpitranscriptomeSupplementaryNote031023.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2679540/v1/328fb7b3dcefc1d2512983f5.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/71db9c463f8c5446731402d5aef7b63bae38535e361ac2d5c86ef745bbe875aa/metadata.json b/71db9c463f8c5446731402d5aef7b63bae38535e361ac2d5c86ef745bbe875aa/metadata.json
index c6f102ed0ef2891d61152f54994b70d71fac5079..869d314f51e62c2ebf4a8713fbe915fb7ca0686e 100644
--- a/71db9c463f8c5446731402d5aef7b63bae38535e361ac2d5c86ef745bbe875aa/metadata.json
+++ b/71db9c463f8c5446731402d5aef7b63bae38535e361ac2d5c86ef745bbe875aa/metadata.json
@@ -166,5 +166,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupportingInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3347713/v1/b993880a47b86fbdb665f536.docx"
+        },
+        {
+            "title": "NCOMMS2342987RS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3347713/v1/ee389d614d69b6ab9894ae7f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7206d39aac3140f44125036e400400f2bc6214730597409b3eca3742f3fd110f/metadata.json b/7206d39aac3140f44125036e400400f2bc6214730597409b3eca3742f3fd110f/metadata.json
index 655c741f4d8a9f9025193d70db48707bf8c218cd..5467c3fb78793e03d763c80e91181ba7b4dfa8f0 100644
--- a/7206d39aac3140f44125036e400400f2bc6214730597409b3eca3742f3fd110f/metadata.json
+++ b/7206d39aac3140f44125036e400400f2bc6214730597409b3eca3742f3fd110f/metadata.json
@@ -160,5 +160,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementarytable.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5886826/v1/a027a850301dd664f268d773.xlsx"
+        },
+        {
+            "title": "Supplementaryfiguresandtables.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5886826/v1/d29ea63665815bf3cb5ba5ef.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/731a230687415d6d36aaefcaacecb0f5cf58a78b243d6de90d62a8aa5dd99a0c/metadata.json b/731a230687415d6d36aaefcaacecb0f5cf58a78b243d6de90d62a8aa5dd99a0c/metadata.json
index 4c2e416f33d23f73654df4b4fd807767cf047a17..7f07d1d26c95142530c13731f250959fe48bfc6b 100644
--- a/731a230687415d6d36aaefcaacecb0f5cf58a78b243d6de90d62a8aa5dd99a0c/metadata.json
+++ b/731a230687415d6d36aaefcaacecb0f5cf58a78b243d6de90d62a8aa5dd99a0c/metadata.json
@@ -138,5 +138,15 @@
             "section_text": "Scientific Reports (2025)\n\nScientific Reports (2025)\n\nWorld Journal of Pediatrics (2024)\n\nCommunications Medicine (2023)\n\nScientific Reports (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "COVAC01StatisticalAnalysisPlanV1.1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1327020/v1/ebb721b68a2eb7390bd8997c.pdf"
+        },
+        {
+            "title": "COVAC01ProtocolV6.1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1327020/v1/bafae7c854dad0e8c0976c30.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7329c365184db0d565099581b1cfbb6f0161d689a0c9d63c319a0b43f6297141/metadata.json b/7329c365184db0d565099581b1cfbb6f0161d689a0c9d63c319a0b43f6297141/metadata.json
index beb3babe4682eaddd636d9ff11f085d376bb198b..7f9af1ba3fa9ba2656b3da20e2edf2fadd27731f 100644
--- a/7329c365184db0d565099581b1cfbb6f0161d689a0c9d63c319a0b43f6297141/metadata.json
+++ b/7329c365184db0d565099581b1cfbb6f0161d689a0c9d63c319a0b43f6297141/metadata.json
@@ -155,5 +155,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "OrbiSIMSNoiseSupportingInfov04.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3911895/v1/9ece7959feb10e9ffbceb9ee.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/73d98d5d8881c1121820f198da89ce38f6166c0dfb248619a19f4a6fe2655129/metadata.json b/73d98d5d8881c1121820f198da89ce38f6166c0dfb248619a19f4a6fe2655129/metadata.json
index e0ff2e22cf250c9791a203f2f373c98245eafb1a..722a5c0c27a3e0cea129bd8d8d73b7d8deda21ee 100644
--- a/73d98d5d8881c1121820f198da89ce38f6166c0dfb248619a19f4a6fe2655129/metadata.json
+++ b/73d98d5d8881c1121820f198da89ce38f6166c0dfb248619a19f4a6fe2655129/metadata.json
@@ -217,5 +217,11 @@
             "section_text": "Nature Ecology & Evolution (2025)\n\nNature Ecology & Evolution (2025)\n\nNature (2025)\n\nTheoretical and Applied Genetics (2025)\n\nPlanta (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "repadaptmethodsandsuppsvNature.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3434061/v1/c16b1f4e4219ad6e972dcb0c.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/748dba856ef92eeef811d187e996cf1aa44407a69761618224ab8f3d40930e14/metadata.json b/748dba856ef92eeef811d187e996cf1aa44407a69761618224ab8f3d40930e14/metadata.json
index 626babc583cf7b03870be20ce3852e994b96bebf..cd323a2092f53faba950d9c26bbb42be63ddf8d0 100644
--- a/748dba856ef92eeef811d187e996cf1aa44407a69761618224ab8f3d40930e14/metadata.json
+++ b/748dba856ef92eeef811d187e996cf1aa44407a69761618224ab8f3d40930e14/metadata.json
@@ -169,5 +169,11 @@
             "section_text": "Nature Communications (2025)\n\nCommunications Earth & Environment (2025)\n\nCommunications Earth & Environment (2025)\n\nnpj Climate and Atmospheric Science (2025)\n\nNature Geoscience (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryMaterial.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-267288/v1/b4aa2128ddc99afb5b41e247.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/75e9ef39b6f62ccf75bf229214b8407721f93bbe3c31b7adc5d4915bc2db951c/metadata.json b/75e9ef39b6f62ccf75bf229214b8407721f93bbe3c31b7adc5d4915bc2db951c/metadata.json
index f697a5f11999f0c48fbad7d53ece7d8013bd8ff7..3756c8cacff8e5a00c7b86ddcc8beea15e7d1ffe 100644
--- a/75e9ef39b6f62ccf75bf229214b8407721f93bbe3c31b7adc5d4915bc2db951c/metadata.json
+++ b/75e9ef39b6f62ccf75bf229214b8407721f93bbe3c31b7adc5d4915bc2db951c/metadata.json
@@ -145,5 +145,11 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinginformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4432970/v1/35927f0127c813d02c5d71ab.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7699436b94e612dc84bfef10f9fea0b14d94391ccf673adf80042aed0a39cab6/metadata.json b/7699436b94e612dc84bfef10f9fea0b14d94391ccf673adf80042aed0a39cab6/metadata.json
index d34a1dddfb2b259e7beaac5fbc33fafcb0a0cd49..6e65e36832f4d7d8f80df6a9db7149bddb22c066 100644
--- a/7699436b94e612dc84bfef10f9fea0b14d94391ccf673adf80042aed0a39cab6/metadata.json
+++ b/7699436b94e612dc84bfef10f9fea0b14d94391ccf673adf80042aed0a39cab6/metadata.json
@@ -152,5 +152,11 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NCOMMS2252383Trs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2259938/v1/32dc41e0e214a99ba452e07b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/76b7dd6a04953b696ec1a65fc183a032835ab346752f616d34edef01e65da493/metadata.json b/76b7dd6a04953b696ec1a65fc183a032835ab346752f616d34edef01e65da493/metadata.json
index eeca6cffaf62194c84e185719adc0e597b3540ad..316621e040f4adba884db50b90f49c66df917eb2 100644
--- a/76b7dd6a04953b696ec1a65fc183a032835ab346752f616d34edef01e65da493/metadata.json
+++ b/76b7dd6a04953b696ec1a65fc183a032835ab346752f616d34edef01e65da493/metadata.json
@@ -169,5 +169,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTablesV18.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3338723/v1/0856eaa727d6f66a7a0f24ca.xlsx"
+        },
+        {
+            "title": "SupplementaryMaterial.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3338723/v1/260bf7b686abee5ea30ef9cc.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/778ea26dab6bd3ec8def49d1fc597536a586f8e61866a905240cd17e52a48efd/metadata.json b/778ea26dab6bd3ec8def49d1fc597536a586f8e61866a905240cd17e52a48efd/metadata.json
index 587e08c2cdbade2693064c705967bb7593765d66..9232b523628f1f2ae38df27dda228f2f89cc4c1f 100644
--- a/778ea26dab6bd3ec8def49d1fc597536a586f8e61866a905240cd17e52a48efd/metadata.json
+++ b/778ea26dab6bd3ec8def49d1fc597536a586f8e61866a905240cd17e52a48efd/metadata.json
@@ -155,5 +155,23 @@
             "section_text": "Insectes Sociaux (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Table1subnat.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4107339/v1/21ff6d669b167a25254530cc.docx"
+        },
+        {
+            "title": "TableS1subnat.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4107339/v1/b0ca89218bc4ebe21b413121.docx"
+        },
+        {
+            "title": "TableS2subnat.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4107339/v1/096ebc4a1c63ba45f999fc81.docx"
+        },
+        {
+            "title": "Supplementarysubnat.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4107339/v1/417b48de84caa032d9bb2a3c.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/77b45db9207c39064b1e3d1e50ab1b0601de5f76f9df9909d5ec3ea50c753f0d/metadata.json b/77b45db9207c39064b1e3d1e50ab1b0601de5f76f9df9909d5ec3ea50c753f0d/metadata.json
index 117793897fef73c3fbf1b8b55e821a123b56464f..2601d5084526308b3809c9d2a5cb1fcb2052fbd7 100644
--- a/77b45db9207c39064b1e3d1e50ab1b0601de5f76f9df9909d5ec3ea50c753f0d/metadata.json
+++ b/77b45db9207c39064b1e3d1e50ab1b0601de5f76f9df9909d5ec3ea50c753f0d/metadata.json
@@ -146,5 +146,15 @@
             "section_text": "Collection\n\nCollection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2860638/v1/c962f87414d4464809ed21c0.pdf"
+        },
+        {
+            "title": "DataandScripts.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2860638/v1/149edb83de110e9f6eff56a2.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7a1346c3aa71ed66364e22f3b62d4233d0336f45a947230a0106c21275f96ec9/metadata.json b/7a1346c3aa71ed66364e22f3b62d4233d0336f45a947230a0106c21275f96ec9/metadata.json
index 7267f6dc15248166513c151df8a23a0f61181bc1..7559bd4f0eeb3467f26c4a3666425ea204bc0726 100644
--- a/7a1346c3aa71ed66364e22f3b62d4233d0336f45a947230a0106c21275f96ec9/metadata.json
+++ b/7a1346c3aa71ed66364e22f3b62d4233d0336f45a947230a0106c21275f96ec9/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Nature Materials (2025)\n\nJournal of Electroceramics (2025)\n\nnpj Computational Materials (2024)\n\nNature Communications (2024)\n\nScience China Materials (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-152905/v1/a31d6e5e2a83db99e607865a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7c946f5da4e9b313403273dd8670531797c503279ca27f51961dab0e8e8d8b13/metadata.json b/7c946f5da4e9b313403273dd8670531797c503279ca27f51961dab0e8e8d8b13/metadata.json
index c47fa8a90c79fe90d9f3bccbb25159ec6c8159f4..dc4d230d7fbbdeda78aba9040cecbeb8653f0907 100644
--- a/7c946f5da4e9b313403273dd8670531797c503279ca27f51961dab0e8e8d8b13/metadata.json
+++ b/7c946f5da4e9b313403273dd8670531797c503279ca27f51961dab0e8e8d8b13/metadata.json
@@ -167,5 +167,19 @@
             "section_text": "Virology Journal (2025)\n\nNature Biomedical Engineering (2025)\n\nNature Reviews Methods Primers (2025)\n\nScientific Reports (2025)\n\nnpj Antimicrobials and Resistance (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementarytables.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1231457/v1/2afe181041d0d9e1be4f6f37.docx"
+        },
+        {
+            "title": "Supplementaryvideofile.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1231457/v1/18d6d411727a5aaa57a3c4c8.mov"
+        },
+        {
+            "title": "nrreportingsummaryFERRY.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1231457/v1/9c61d2e59cf6d8eedf957107.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7e1c473154ced3f4c26c8b6bc6a1ccd24c3e92a096ba53571746bb619bcedd31/metadata.json b/7e1c473154ced3f4c26c8b6bc6a1ccd24c3e92a096ba53571746bb619bcedd31/metadata.json
index 9db06dadd896d0fb2a2987c743b1ae116876633a..8e0dc8e220eab6add91db73503932a02331edcb6 100644
--- a/7e1c473154ced3f4c26c8b6bc6a1ccd24c3e92a096ba53571746bb619bcedd31/metadata.json
+++ b/7e1c473154ced3f4c26c8b6bc6a1ccd24c3e92a096ba53571746bb619bcedd31/metadata.json
@@ -171,5 +171,31 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFile1Oligonucleotidesequences.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/17e229be9422a81958dca4c0.xlsx"
+        },
+        {
+            "title": "SupplementaryFile2Antibodies.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/24e5380891172465fa721eb0.xlsx"
+        },
+        {
+            "title": "SupplementaryFile3WGBSbasicmetrics.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/42fd27ebe8639d856e75c56c.xlsx"
+        },
+        {
+            "title": "SupplementaryMovie1UHRF1mClover.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/37fb08375fd0623903a55f97.mp4"
+        },
+        {
+            "title": "SupplementaryMovie2DNMT1mRuby.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/2bb8d7cd5b75207b38de85c4.mp4"
+        },
+        {
+            "title": "SupplementaryMovie3UHRF1mCloverGreenDNMT1mRubyRed.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154646/v1/a7cff191ddf1a32791494f08.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7e6f2e24c1c8d4e3aaa13e2875ea7c7452d975c29a599bbb90931019f462e57c/metadata.json b/7e6f2e24c1c8d4e3aaa13e2875ea7c7452d975c29a599bbb90931019f462e57c/metadata.json
index 6d399443dd25a1eb3f694d7c8c4713ad999f880a..74c04457c272ada1759b14711120e80527f4e1ad 100644
--- a/7e6f2e24c1c8d4e3aaa13e2875ea7c7452d975c29a599bbb90931019f462e57c/metadata.json
+++ b/7e6f2e24c1c8d4e3aaa13e2875ea7c7452d975c29a599bbb90931019f462e57c/metadata.json
@@ -139,5 +139,11 @@
             "section_text": "Experimental & Molecular Medicine (2025)\n\nEthical Theory and Moral Practice (2025)\n\nBMC Public Health (2024)\n\nBMC Medicine (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "adjustedsecondaryattackratesuppmatV2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2510736/v1/2e120ee869e68cdd0b50390d.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/7ea08d3a6b99d16e7f9a32724c54deb41c2325e4e80d5feab1f63b193d958db8/metadata.json b/7ea08d3a6b99d16e7f9a32724c54deb41c2325e4e80d5feab1f63b193d958db8/metadata.json
index 28f348b04ea4141943de06e8a7108273396ab5d4..6ab99153a6885237334730e90819156fd599e7d3 100644
--- a/7ea08d3a6b99d16e7f9a32724c54deb41c2325e4e80d5feab1f63b193d958db8/metadata.json
+++ b/7ea08d3a6b99d16e7f9a32724c54deb41c2325e4e80d5feab1f63b193d958db8/metadata.json
@@ -201,5 +201,15 @@
             "section_text": "Experimental & Molecular Medicine (2025)\n\nHuman Cell (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NatCommunSupplementalData.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1807575/v1/5f9d18bb335eeb092c98e08c.xlsx"
+        },
+        {
+            "title": "NatCommunSupplementalFigXTextXTab.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1807575/v1/4c57f411dcb54269dc67c41c.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/818cc65d1c84199bb5327eea9f1c5ec4d5ffc65c2db77b15d24cfbbe667ab902/metadata.json b/818cc65d1c84199bb5327eea9f1c5ec4d5ffc65c2db77b15d24cfbbe667ab902/metadata.json
index baf8244c61ea5a3bcd1a35858f8f5d82332437b9..98aafee5a868162bde278959a44d842dc34fcd69 100644
--- a/818cc65d1c84199bb5327eea9f1c5ec4d5ffc65c2db77b15d24cfbbe667ab902/metadata.json
+++ b/818cc65d1c84199bb5327eea9f1c5ec4d5ffc65c2db77b15d24cfbbe667ab902/metadata.json
@@ -174,5 +174,15 @@
             "section_text": "Scientific Reports (2025)\n\nBMC Medicine (2025)\n\nTropical Medicine and Health (2024)\n\nInfection (2024)\n\nBMC Infectious Diseases (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Extendedfiles.rar",
+            "link": "https://assets-eu.researchsquare.com/files/rs-995033/v1/10bc4dc8f081717689b13e3a.rar"
+        },
+        {
+            "title": "ExtendedFiguresandTables.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-995033/v1/13f160e70f5165d523b39bc0.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/85326f1e37dad0b8a3746478f1eb197263bf025ef113911b44ca9306b8bc0a53/metadata.json b/85326f1e37dad0b8a3746478f1eb197263bf025ef113911b44ca9306b8bc0a53/metadata.json
index 2ceda538a0a160f8fc1bfd0e365688511c2482e1..55028d6899e3bbe0a199ca5bb3db922344e52346 100644
--- a/85326f1e37dad0b8a3746478f1eb197263bf025ef113911b44ca9306b8bc0a53/metadata.json
+++ b/85326f1e37dad0b8a3746478f1eb197263bf025ef113911b44ca9306b8bc0a53/metadata.json
@@ -159,5 +159,11 @@
             "section_text": "Plant Biotechnology Reports (2025)\n\nPhotosynthesis Research (2025)\n\nTheoretical and Applied Genetics (2024)\n\nTheoretical and Applied Genetics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformatonbouidghaghen.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2879665/v1/d3b00cb40f300489fb006b80.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/85a42ff1875221f9146c2ded40e960a88d115771b9ac7e629d1f95c498ba15ad/metadata.json b/85a42ff1875221f9146c2ded40e960a88d115771b9ac7e629d1f95c498ba15ad/metadata.json
index 3d172530ef22c276aecede6617edaa02790ce0f4..fd49589613186cc6da2b0abfcf116987de64e80b 100644
--- a/85a42ff1875221f9146c2ded40e960a88d115771b9ac7e629d1f95c498ba15ad/metadata.json
+++ b/85a42ff1875221f9146c2ded40e960a88d115771b9ac7e629d1f95c498ba15ad/metadata.json
@@ -161,5 +161,43 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendedFigure1.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/7ec5521182b955ec98d56177.tif"
+        },
+        {
+            "title": "ExtendedFigure2.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/fa300b756fa6a7b0aea29d4f.tif"
+        },
+        {
+            "title": "ExtendedFigure3microglialrepopulationatvascularlocationsfollowingPLX.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/7c851ae1f0b235a72ff94410.tif"
+        },
+        {
+            "title": "ExtendedFigure4.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/de2a1bf3870650f8aeb488d8.tif"
+        },
+        {
+            "title": "ExtendedFigure52Phatalcontrols.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/49397dd33e38b8dda384cf1e.tif"
+        },
+        {
+            "title": "ExtendedFigure6COX1transcriptionalexpression.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/1e90b0a12499760ecebbc6b5.tif"
+        },
+        {
+            "title": "ExtendedFigure7.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/69b72ae4f16dac19c94d6fb9.tif"
+        },
+        {
+            "title": "ExtendedFigure8.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/f7891fa5eaa3f6fb4292e606.tif"
+        },
+        {
+            "title": "ExtendedFigure9.tif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6149132/v1/b8448706905a8d488d7c7871.tif"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8791b021b61f03bc21e25133184325509afe4356ce4f251b23407463a332db33/metadata.json b/8791b021b61f03bc21e25133184325509afe4356ce4f251b23407463a332db33/metadata.json
index 7fb8f2bbe7ac93ed6d66be50bfdbba5efbb7f584..cd8139f2d5f37f3f4c2c02be04aa938f71ebf238 100644
--- a/8791b021b61f03bc21e25133184325509afe4356ce4f251b23407463a332db33/metadata.json
+++ b/8791b021b61f03bc21e25133184325509afe4356ce4f251b23407463a332db33/metadata.json
@@ -165,5 +165,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "DHES0815ASupplementalfigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2322502/v1/dac96514e504587acfb62326.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/87ee35b4b0d5d3dcd42d47fdbb8cd27584473771f2307937fb62faad99105fde/metadata.json b/87ee35b4b0d5d3dcd42d47fdbb8cd27584473771f2307937fb62faad99105fde/metadata.json
index 557a519532d01e56a4decd87922d7f20e6008d42..a4205f57e16de35053d968045756b4615bd1c229 100644
--- a/87ee35b4b0d5d3dcd42d47fdbb8cd27584473771f2307937fb62faad99105fde/metadata.json
+++ b/87ee35b4b0d5d3dcd42d47fdbb8cd27584473771f2307937fb62faad99105fde/metadata.json
@@ -151,5 +151,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "FigureS1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4320313/v1/c9816a74854e28922a34568d.pdf"
+        },
+        {
+            "title": "FigureS2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4320313/v1/270035b830f4dd8ef510b531.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/87ffb794d1cd82106b7e3de51cef9c54cb9e67ed492c80747aa158d8201ab6ee/metadata.json b/87ffb794d1cd82106b7e3de51cef9c54cb9e67ed492c80747aa158d8201ab6ee/metadata.json
index 9705d6f345f6015c5a1ccb11f426af9f9b6da837..8771817fcb88f18a2dc51e795e7df12a56ebf35c 100644
--- a/87ffb794d1cd82106b7e3de51cef9c54cb9e67ed492c80747aa158d8201ab6ee/metadata.json
+++ b/87ffb794d1cd82106b7e3de51cef9c54cb9e67ed492c80747aa158d8201ab6ee/metadata.json
@@ -161,5 +161,11 @@
             "section_text": "Molecular Psychiatry (2025)\n\nMolecular Psychiatry (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SuppleFiguresv6.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-899531/v1/4e1e70bccd6ebaba130f74c7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/88842ca97d9c636605bf056d969855d63b2ce322a76ebc1254e37e55af7092c3/metadata.json b/88842ca97d9c636605bf056d969855d63b2ce322a76ebc1254e37e55af7092c3/metadata.json
index 5be87573988e867d5d07e54a6af4601dac1a2d6f..2c9801ab3cfb5b608f7bd1fdc7a6082409ea38be 100644
--- a/88842ca97d9c636605bf056d969855d63b2ce322a76ebc1254e37e55af7092c3/metadata.json
+++ b/88842ca97d9c636605bf056d969855d63b2ce322a76ebc1254e37e55af7092c3/metadata.json
@@ -159,5 +159,15 @@
             "section_text": "Commenting on this article is now closed.\n\nGrant Castillou 14 November 2022, 20:24\n\nIt's becoming clear that with all the brain and consciousness theories out there, the proof will be in the pudding. By this I mean, can any particular theory be used to create a human adult level conscious machine. My bet is on the late Gerald Edelman's Extended Theory of Neuronal Group Selection. The lead group in robotics based on this theory is the Neurorobotics Lab at UC at Irvine.  Dr. Edelman distinguished between primary consciousness, which came first in evolution, and that humans share with other conscious animals, and higher order consciousness, which came to only humans with the acquisition of language.  A machine with primary consciousness will probably have to come first.\n\nWhat I find special about the TNGS is the Darwin series of automata created at the Neurosciences Institute by Dr. Edelman and his colleagues in the 1990's and 2000's.  These machines perform in the real world, not in a restricted simulated world, and display convincing physical behavior indicative of higher psychological functions necessary for consciousness, such as perceptual categorization, memory, and learning.  They are based on realistic models of the parts of the biological brain that the theory claims subserve these functions.  The extended TNGS allows for the emergence of consciousness based only on further evolutionary development of the brain areas responsible for these functions, in a parsimonious way.  No other research I've encountered is anywhere near as convincing.\n\n I post because on almost every video and article about the brain and consciousness that I encounter,  the attitude seems to be that we still know next to nothing about how the brain and consciousness work; that there's lots of data but no unifying theory.  I believe the extended TNGS  is that theory.  My motivation is to keep that theory in front of the public.  And obviously, I consider it the route to a truly conscious machine, primary and higher-order.\n\nMy advice to people who want to create a conscious machine is to seriously ground themselves in the extended TNGS and the Darwin automata first, and proceed from there, by applying to Jeff Krichmar's lab at UC Irvine, possibly. Dr. Edelman's roadmap to a conscious machine is at https://arxiv.org/abs/2105....",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "BinocularRivalrySI2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-646785/v1/aa716fd575aed773e8c1d417.pdf"
+        },
+        {
+            "title": "NCOMMS2124200rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-646785/v1/abfb34bb594ae53fe17f7a3d.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/891fc89fc9674d2886a5fb98720fc99936cdb8d2a882f09f2a21452681fb0743/metadata.json b/891fc89fc9674d2886a5fb98720fc99936cdb8d2a882f09f2a21452681fb0743/metadata.json
index d56fc502d956b3dc2de2a3c1b6f66da2df524206..72762cce508d43f3efb32887f000ba0d7862bbbe 100644
--- a/891fc89fc9674d2886a5fb98720fc99936cdb8d2a882f09f2a21452681fb0743/metadata.json
+++ b/891fc89fc9674d2886a5fb98720fc99936cdb8d2a882f09f2a21452681fb0743/metadata.json
@@ -190,5 +190,15 @@
             "section_text": "Nature Communications (2025)\n\nInternational Journal of System Assurance Engineering and Management (2024)\n\nNature Communications (2022)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryResultsHiCLSTM.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-878825/v1/f62928751fc21d265012f21d.pdf"
+        },
+        {
+            "title": "rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-878825/v1/030f6c3b9f8e78c25fd01911.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/89f0c1c2bd3340a58766f62539d904de96a4c7e379c22732ad1ef282521de2e7/metadata.json b/89f0c1c2bd3340a58766f62539d904de96a4c7e379c22732ad1ef282521de2e7/metadata.json
index f6243f847cedb50cce8f99ae47124ae424a278c3..69cf7651b053a30101bace7148419f3afb54b5a2 100644
--- a/89f0c1c2bd3340a58766f62539d904de96a4c7e379c22732ad1ef282521de2e7/metadata.json
+++ b/89f0c1c2bd3340a58766f62539d904de96a4c7e379c22732ad1ef282521de2e7/metadata.json
@@ -141,5 +141,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2024)\n\nNano-Micro Letters (2024)\n\nNature Reviews Materials (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIThermodynamicsofOECTs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1143463/v1/ef3e34088a9bc199a7ec4d19.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8a1e092682b94cf2a7396d71e4e3c1d5cc89620e7028b49d31e1b31650b00462/metadata.json b/8a1e092682b94cf2a7396d71e4e3c1d5cc89620e7028b49d31e1b31650b00462/metadata.json
index 4b337944ec66bc39c1177a7b646a1981c1598520..bd17b3b3d5e461e5a8300ab362753d8e543065da 100644
--- a/8a1e092682b94cf2a7396d71e4e3c1d5cc89620e7028b49d31e1b31650b00462/metadata.json
+++ b/8a1e092682b94cf2a7396d71e4e3c1d5cc89620e7028b49d31e1b31650b00462/metadata.json
@@ -149,5 +149,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "RodriguesetalCompoundEventsSouthAtlanticSuppMaterial.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4863778/v1/f61da0bc460e958c018d7b07.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8a9a1d59df396cb756acb04a5be9f4830ae9a00511115f1c97f27f17ec195a92/metadata.json b/8a9a1d59df396cb756acb04a5be9f4830ae9a00511115f1c97f27f17ec195a92/metadata.json
index 944c9cbd65579d394d675e64fe1a259c9c55c44e..161c8bd41d430d15c8398030573216568e61d0da 100644
--- a/8a9a1d59df396cb756acb04a5be9f4830ae9a00511115f1c97f27f17ec195a92/metadata.json
+++ b/8a9a1d59df396cb756acb04a5be9f4830ae9a00511115f1c97f27f17ec195a92/metadata.json
@@ -165,5 +165,19 @@
             "section_text": "Nature Communications (2025)\n\nScience China Chemistry (2025)\n\nScience China Chemistry (2025)\n\nJournal of Nanobiotechnology (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ZTPEEPy.cif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1688722/v1/3da844d39e5b7e76c5e6cfff.cif"
+        },
+        {
+            "title": "ETPEEPy.cif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1688722/v1/5a28625140c146d15158da3e.cif"
+        },
+        {
+            "title": "SupportingInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1688722/v1/cad5b9924ebf80229a66f889.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8ad1d2ea1d165cfb52d74e74eb3c88e5152e7f64ac68578197b2d880bfd4b93d/metadata.json b/8ad1d2ea1d165cfb52d74e74eb3c88e5152e7f64ac68578197b2d880bfd4b93d/metadata.json
index 3cda718b94ddfbd2497003840a1ef975fae3f9e4..ebbb04ce5fd64addc3adc26eb29fb4b52cd53cd5 100644
--- a/8ad1d2ea1d165cfb52d74e74eb3c88e5152e7f64ac68578197b2d880bfd4b93d/metadata.json
+++ b/8ad1d2ea1d165cfb52d74e74eb3c88e5152e7f64ac68578197b2d880bfd4b93d/metadata.json
@@ -170,5 +170,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Video1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5102269/v1/bfe1141b86c729d1fbbe3127.mp4"
+        },
+        {
+            "title": "LiLSIMNatureCommsSuppl.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5102269/v1/e600ee95a148686ca933a4a6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8bb085e15fdf0079d1945e4cdd5ba476d12bf79ab4dd2caeab652f174fe240b0/metadata.json b/8bb085e15fdf0079d1945e4cdd5ba476d12bf79ab4dd2caeab652f174fe240b0/metadata.json
index 090d486e848f6b077e97bfd6a6bb18b175d9327a..e491a0bc516d748eea9c5fe23fd58723865b201f 100644
--- a/8bb085e15fdf0079d1945e4cdd5ba476d12bf79ab4dd2caeab652f174fe240b0/metadata.json
+++ b/8bb085e15fdf0079d1945e4cdd5ba476d12bf79ab4dd2caeab652f174fe240b0/metadata.json
@@ -151,5 +151,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "20231207Supp.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3720367/v1/92eb56eefd46d85213b96efd.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8c9b94bb6f1884cc0a564e761105a3eff631f1b7e27657d4ddcdfa557ec1b3f3/metadata.json b/8c9b94bb6f1884cc0a564e761105a3eff631f1b7e27657d4ddcdfa557ec1b3f3/metadata.json
index 3666857a3a97e2d9b34fc6e20494aac48020269f..38fa686c83b8c6edd515400d7654c70506fb9f3f 100644
--- a/8c9b94bb6f1884cc0a564e761105a3eff631f1b7e27657d4ddcdfa557ec1b3f3/metadata.json
+++ b/8c9b94bb6f1884cc0a564e761105a3eff631f1b7e27657d4ddcdfa557ec1b3f3/metadata.json
@@ -145,5 +145,11 @@
             "section_text": "Nature Communications (2025)\n\nScience China Chemistry (2025)\n\nScience China Chemistry (2025)\n\nJournal of Materials Science: Materials in Electronics (2025)\n\nScience China Chemistry (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "CuZnOMsSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-137209/v1/476d3d7dba8019a57b4028a4.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8d52bd7b38031888a09c14c5203b943d075ce883234c8d9d06e81164a8fb0515/metadata.json b/8d52bd7b38031888a09c14c5203b943d075ce883234c8d9d06e81164a8fb0515/metadata.json
index 4f0d6714975b215cbd2bd13da0dc222bf48ecaeb..a6b8acfc06b89642970870eb15d51cac650e5716 100644
--- a/8d52bd7b38031888a09c14c5203b943d075ce883234c8d9d06e81164a8fb0515/metadata.json
+++ b/8d52bd7b38031888a09c14c5203b943d075ce883234c8d9d06e81164a8fb0515/metadata.json
@@ -185,5 +185,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI12hourphenotypicdrugsusceptibilitytestingforMycobacteriumtuberculosisvariantbovisBCGv2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5052218/v1/c9bc18765cf5bf10371f7549.pdf"
+        },
+        {
+            "title": "SISegmentationperformanceofOmniposeonmycobacteriadata.pptx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5052218/v1/2d002850d0c35f97667c1227.pptx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8d7b7ecec5e7c3a9fc377672e2c129b9c8121d75c2c8603a5840b2789010f3fb/metadata.json b/8d7b7ecec5e7c3a9fc377672e2c129b9c8121d75c2c8603a5840b2789010f3fb/metadata.json
index 1511650bc23c63a7507435d0721af5d0719f7077..49524da933dba6555b570ec48a7c8877546e0d44 100644
--- a/8d7b7ecec5e7c3a9fc377672e2c129b9c8121d75c2c8603a5840b2789010f3fb/metadata.json
+++ b/8d7b7ecec5e7c3a9fc377672e2c129b9c8121d75c2c8603a5840b2789010f3fb/metadata.json
@@ -177,5 +177,39 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Movie1homogeneoustheory.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/89758ff70e0578b023798075.mp4"
+        },
+        {
+            "title": "Movie2heterogeneoustheory.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/e19a6743a004acf671f839d1.mp4"
+        },
+        {
+            "title": "Movie3ControlBP.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/2bc2bc4f00ba6dd7707260c6.avi"
+        },
+        {
+            "title": "Movie4ML7treatedBP.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/5c2ed77e6fb6ed1099732e0a.avi"
+        },
+        {
+            "title": "Movie5Inhibitionintheory.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/3dce3ce6e6dff963e5153539.mp4"
+        },
+        {
+            "title": "Movie6PTXtreatedBP.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/b4377be66c9474b01d783f7e.avi"
+        },
+        {
+            "title": "Movie7modelwithasymmetries.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/bb9fd13e09d2a31b4147bfe3.mp4"
+        },
+        {
+            "title": "Movie8modelwithasymmetryandcurvature.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2508957/v1/3e11fa87dcce1fe9062ab8dd.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8e05d8dd0ccec5a9bfab5e281b1b04f2186ebf5d1ae10bf86aade5b8dc6cb4f8/metadata.json b/8e05d8dd0ccec5a9bfab5e281b1b04f2186ebf5d1ae10bf86aade5b8dc6cb4f8/metadata.json
index 155c4964604a2211cb71acfc847712da47ec2e56..e99432318aaf5118cf7f6733993ebfc435edd575 100644
--- a/8e05d8dd0ccec5a9bfab5e281b1b04f2186ebf5d1ae10bf86aade5b8dc6cb4f8/metadata.json
+++ b/8e05d8dd0ccec5a9bfab5e281b1b04f2186ebf5d1ae10bf86aade5b8dc6cb4f8/metadata.json
@@ -178,5 +178,23 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIGuide.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1909545/v1/3948817674b070a38219f021.docx"
+        },
+        {
+            "title": "SupplementaryTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1909545/v1/35e13e3ff64df07a8e0cbaf7.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1909545/v1/8fc7b30ed57eac904784662c.xlsx"
+        },
+        {
+            "title": "NCOMMS2235634Trs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1909545/v1/cc07677b6064cec5e006fd32.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/8eadda528bffeb2113e9b4f8831b8baf266c7ea569654f004813194147aa5ff2/metadata.json b/8eadda528bffeb2113e9b4f8831b8baf266c7ea569654f004813194147aa5ff2/metadata.json
index 59f8dc473b8fdd68af20d6568408a0d1f1460900..2da2d34e2f1b5b79ea5bf820c41d43c6ea053f33 100644
--- a/8eadda528bffeb2113e9b4f8831b8baf266c7ea569654f004813194147aa5ff2/metadata.json
+++ b/8eadda528bffeb2113e9b4f8831b8baf266c7ea569654f004813194147aa5ff2/metadata.json
@@ -152,5 +152,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "VolcanoSV20240107SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3843810/v1/aa50e5e0e35c7a8b8396ba07.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9016ddbcb377cf6a0d6be1b335e6a7fa8ee7c9a8dda5e10df9ef2347289fdd34/metadata.json b/9016ddbcb377cf6a0d6be1b335e6a7fa8ee7c9a8dda5e10df9ef2347289fdd34/metadata.json
index d8dfcfa4db653585ffb36c089905a8b164c27781..eb407c5f144f69b3c3e072a86ca50cfa8461bc07 100644
--- a/9016ddbcb377cf6a0d6be1b335e6a7fa8ee7c9a8dda5e10df9ef2347289fdd34/metadata.json
+++ b/9016ddbcb377cf6a0d6be1b335e6a7fa8ee7c9a8dda5e10df9ef2347289fdd34/metadata.json
@@ -201,5 +201,19 @@
             "section_text": "Journal of Orthopaedic Surgery and Research (2025)\n\nNature Communications (2025)\n\nIndian Journal of Physics (2025)\n\nJournal of Nanobiotechnology (2024)\n\nBMC Musculoskeletal Disorders (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Video1Invivo3DNIRIImousetibiaimaging.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2582295/v1/649e9ee7b7be1a785356526b.mp4"
+        },
+        {
+            "title": "Video2Exvivo3DNIRIImousetibiaimaging.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2582295/v1/b5a35651212e0b3d11fd93dd.mp4"
+        },
+        {
+            "title": "Supplementaryinformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2582295/v1/119d6e321246df8a5e529a18.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/904a23644017e1eb32facd9cb85aba879565a19438f3ebf2e5f8530ca754c689/metadata.json b/904a23644017e1eb32facd9cb85aba879565a19438f3ebf2e5f8530ca754c689/metadata.json
index 7bfc9613c2b7827ce587b4079b0c41373bc56667..4c488c454c9311aeb011fe1aa41166978cf18260 100644
--- a/904a23644017e1eb32facd9cb85aba879565a19438f3ebf2e5f8530ca754c689/metadata.json
+++ b/904a23644017e1eb32facd9cb85aba879565a19438f3ebf2e5f8530ca754c689/metadata.json
@@ -147,5 +147,11 @@
             "section_text": "BMC Global and Public Health (2025)\n\nScientific Reports (2025)\n\nScientific Reports (2025)\n\nnpj Complexity (2025)\n\nInternational Journal of Data Science and Analytics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1033571/v1/435b0b8b8805d620d020e2d1.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/90d66c3f5dad31570852d1ae0a1476bd5de10b7c013434af556b2c7c95be395d/metadata.json b/90d66c3f5dad31570852d1ae0a1476bd5de10b7c013434af556b2c7c95be395d/metadata.json
index 0f685b9b5134acb7f0ec8e364bf76b004ca0031e..895c9b7bf922246f3db0ae2bb5f6604217bded23 100644
--- a/90d66c3f5dad31570852d1ae0a1476bd5de10b7c013434af556b2c7c95be395d/metadata.json
+++ b/90d66c3f5dad31570852d1ae0a1476bd5de10b7c013434af556b2c7c95be395d/metadata.json
@@ -153,5 +153,11 @@
             "section_text": "Journal of Translational Medicine (2025)\n\nCell Death & Disease (2025)\n\nCell Death Discovery (2025)\n\nNature Biotechnology (2025)\n\nCytotechnology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementarymaterials.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2404504/v1/45a579719f9be9db17eb1b12.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9151962785a654b9595ad90152cf4ed8e572b258ead48302bdce52b75e445aec/metadata.json b/9151962785a654b9595ad90152cf4ed8e572b258ead48302bdce52b75e445aec/metadata.json
index 47d0ce9a2c9fdb2ede7567f691811f94e0bef007..56716a6ff14a8b5084c86fe38300a503e9dc00b1 100644
--- a/9151962785a654b9595ad90152cf4ed8e572b258ead48302bdce52b75e445aec/metadata.json
+++ b/9151962785a654b9595ad90152cf4ed8e572b258ead48302bdce52b75e445aec/metadata.json
@@ -161,5 +161,19 @@
             "section_text": "Nature Communications (2025)\n\nNaunyn-Schmiedeberg's Archives of Pharmacology (2025)\n\nApplied Biochemistry and Biotechnology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementalNatComms2023FINAL.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3143359/v1/209218c17c037eb29c3d59c8.docx"
+        },
+        {
+            "title": "softwarepolicy.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3143359/v1/3cea7cfc610f9bbd766a39ea.pdf"
+        },
+        {
+            "title": "RS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3143359/v1/e5eb907f3c8bb7d4eca05785.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/923daaf6d6c84e51a943b4920e071ca6840a3ba818659bd25b99c75911688fb3/metadata.json b/923daaf6d6c84e51a943b4920e071ca6840a3ba818659bd25b99c75911688fb3/metadata.json
index fed645a56413c480d5e4d2278db217d095db6966..67cc2e8efded42a5c6e27cac0ebced9f439af739 100644
--- a/923daaf6d6c84e51a943b4920e071ca6840a3ba818659bd25b99c75911688fb3/metadata.json
+++ b/923daaf6d6c84e51a943b4920e071ca6840a3ba818659bd25b99c75911688fb3/metadata.json
@@ -132,5 +132,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5500958/v1/cd187e2c827ee6a0524a5cba.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9272bbefc0a51467d23970391afa79520bef1495007ab1ffc41d2e7aefb38835/metadata.json b/9272bbefc0a51467d23970391afa79520bef1495007ab1ffc41d2e7aefb38835/metadata.json
index 42e38ceaf2703b4136c14e0fff851d00cb350295..24820f9bbb0a407e793f843494dade6f3b64fdfa 100644
--- a/9272bbefc0a51467d23970391afa79520bef1495007ab1ffc41d2e7aefb38835/metadata.json
+++ b/9272bbefc0a51467d23970391afa79520bef1495007ab1ffc41d2e7aefb38835/metadata.json
@@ -166,5 +166,11 @@
             "section_text": "Collection\n\nFocus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3715425/v1/2d82bd52c1dc984c865f8f2b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/930d540da429eee1dee1d63b3c7c34b2d27099a5acec95d7404fac7959ade823/metadata.json b/930d540da429eee1dee1d63b3c7c34b2d27099a5acec95d7404fac7959ade823/metadata.json
index 107435472ae910ce06f5470c08a13083087b00b4..7b03172de92cbf90c168aa96e4aea76e025f2f61 100644
--- a/930d540da429eee1dee1d63b3c7c34b2d27099a5acec95d7404fac7959ade823/metadata.json
+++ b/930d540da429eee1dee1d63b3c7c34b2d27099a5acec95d7404fac7959ade823/metadata.json
@@ -150,5 +150,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MECHSSupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3898282/v1/516c49566e5552371dfab937.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/936bc1d66b35ab80d9761ed6dd03e6ab67e2d0a74236f36c7ace4dd9b02eff29/metadata.json b/936bc1d66b35ab80d9761ed6dd03e6ab67e2d0a74236f36c7ace4dd9b02eff29/metadata.json
index 2e63585ddce472443fe3c6a9d8859ec4ff7207ed..4ed274c480062c54f38c20fa2668d0e673fb3b0e 100644
--- a/936bc1d66b35ab80d9761ed6dd03e6ab67e2d0a74236f36c7ace4dd9b02eff29/metadata.json
+++ b/936bc1d66b35ab80d9761ed6dd03e6ab67e2d0a74236f36c7ace4dd9b02eff29/metadata.json
@@ -168,5 +168,11 @@
             "section_text": "Biology of Sex Differences (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-290304/v1/aed683e427f0d40e1a2f63f9.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/93df9d9b42a1334a483938f19fc6c668d0d4f16066613a4d8d7fabcb0a8589f5/metadata.json b/93df9d9b42a1334a483938f19fc6c668d0d4f16066613a4d8d7fabcb0a8589f5/metadata.json
index b2bff8de362a4e2d3c824f03ff4a338bcd46e6e7..88432b89487b62adfeb5233fa18856e421759514 100644
--- a/93df9d9b42a1334a483938f19fc6c668d0d4f16066613a4d8d7fabcb0a8589f5/metadata.json
+++ b/93df9d9b42a1334a483938f19fc6c668d0d4f16066613a4d8d7fabcb0a8589f5/metadata.json
@@ -134,5 +134,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "KellyetalManuscriptSupplementalv4submitted.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-116308/v1/4d5640b477071376135d7ade.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9507ba833aac9d76a645252cc2f73eb413bf634eb8029d3f99d3607b1d63b439/metadata.json b/9507ba833aac9d76a645252cc2f73eb413bf634eb8029d3f99d3607b1d63b439/metadata.json
index 677d52b443b5925bbc9cc40d90e427bba820bf97..b3d13eccd4fc31a01e23acb5a4eec5ddc207e322 100644
--- a/9507ba833aac9d76a645252cc2f73eb413bf634eb8029d3f99d3607b1d63b439/metadata.json
+++ b/9507ba833aac9d76a645252cc2f73eb413bf634eb8029d3f99d3607b1d63b439/metadata.json
@@ -154,5 +154,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "GencSANDINatCommssupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4883534/v1/00e5d059c019f71ce6127055.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/98621a0a9a75bfd4307471acfa62e2ac69cd7da3d48c9482423c2bb4b8db561a/metadata.json b/98621a0a9a75bfd4307471acfa62e2ac69cd7da3d48c9482423c2bb4b8db561a/metadata.json
index c2fc901919dc53ea58037f0ec6b0fe3cb25ba78e..04e477e816097b6600892f134675c45746bf98d0 100644
--- a/98621a0a9a75bfd4307471acfa62e2ac69cd7da3d48c9482423c2bb4b8db561a/metadata.json
+++ b/98621a0a9a75bfd4307471acfa62e2ac69cd7da3d48c9482423c2bb4b8db561a/metadata.json
@@ -148,5 +148,15 @@
             "section_text": "Communications Chemistry (2025)\n\nNature Communications (2025)\n\nBiochemical Genetics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendFigTableLegend.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2819840/v1/cbc27c28059217415a25e69f.pdf"
+        },
+        {
+            "title": "Table.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2819840/v1/688bad9dcec271cfeb745317.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/996a335d085336dc9880221475d34358c76bcd769e11a6cc725b14a00ca20246/metadata.json b/996a335d085336dc9880221475d34358c76bcd769e11a6cc725b14a00ca20246/metadata.json
index 29be8bcd83bd4a7f3f5ebde6a2be0608d234bcea..333fba20b6fc002134dfbd9b2e251403fea0b881 100644
--- a/996a335d085336dc9880221475d34358c76bcd769e11a6cc725b14a00ca20246/metadata.json
+++ b/996a335d085336dc9880221475d34358c76bcd769e11a6cc725b14a00ca20246/metadata.json
@@ -173,5 +173,27 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaltable1.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2714625/v1/fc8da943b07b10fb239b83de.docx"
+        },
+        {
+            "title": "nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2714625/v1/692e4ba7ba8a96a41fdb5ec0.pdf"
+        },
+        {
+            "title": "nrreportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2714625/v1/4d6d2957adc1019033b9fbed.pdf"
+        },
+        {
+            "title": "NCOMMS2322103B2rs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2714625/v1/6b9c1637e396f8491d1a19b4.pdf"
+        },
+        {
+            "title": "ExtendedDataFigures.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2714625/v1/ecfe4d0e7582088757926482.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/99f60a63721bb83d514f6ad00f9e746770fed14bc32d2ddbaf7e58c6f4eac606/metadata.json b/99f60a63721bb83d514f6ad00f9e746770fed14bc32d2ddbaf7e58c6f4eac606/metadata.json
index 5fa070f312985b46f34683134e8900720e19d191..17ef5ccfa78f106c6437124b64386eb98efc603e 100644
--- a/99f60a63721bb83d514f6ad00f9e746770fed14bc32d2ddbaf7e58c6f4eac606/metadata.json
+++ b/99f60a63721bb83d514f6ad00f9e746770fed14bc32d2ddbaf7e58c6f4eac606/metadata.json
@@ -158,5 +158,35 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supportinginformationfinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/6274a69da8b02bb0de8085ba.pdf"
+        },
+        {
+            "title": "NatureCommSourcefile2ndrev.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/cba7f176604ce9d745dbcfcc.xlsx"
+        },
+        {
+            "title": "SIVideo1KCln0p45C.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/40d0af8bc4497af229846b7e.mp4"
+        },
+        {
+            "title": "SIVideo2KCln0p05C.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/ed0c288403c77332fd028877.mp4"
+        },
+        {
+            "title": "SIVideo3CaCl2n0p55C.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/a0866e9f54d5b214b4ca340d.mp4"
+        },
+        {
+            "title": "SIVideo4CaCl2n0p40C.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/4184a753d9f7d543023994b4.mp4"
+        },
+        {
+            "title": "SIVideo5CaCl2n0p15C.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4376877/v1/d7906c6d6bd865607477b772.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9a089f0b64c6026722341d9bd6fbee1b9fe022f02b0d640b071fae68318f7313/metadata.json b/9a089f0b64c6026722341d9bd6fbee1b9fe022f02b0d640b071fae68318f7313/metadata.json
index b1a1815201450ea4c2eab933284de8627eceae77..9252a838366782429f9d770923249d6f6fb282cb 100644
--- a/9a089f0b64c6026722341d9bd6fbee1b9fe022f02b0d640b071fae68318f7313/metadata.json
+++ b/9a089f0b64c6026722341d9bd6fbee1b9fe022f02b0d640b071fae68318f7313/metadata.json
@@ -158,5 +158,15 @@
             "section_text": "npj Aging (2025)\n\nJournal of Molecular Evolution (2025)\n\nMolecular Cancer (2025)\n\nNature Aging (2025)\n\nNature Aging (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Anerillasetal.SupplementaryTableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1263555/v1/657382ddf4c41ce3bc66fa8f.xlsx"
+        },
+        {
+            "title": "Anerillasetal.SupplementalTextandFigurescombined.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1263555/v1/0f37502e6afcbce0546acfb7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9c94f08b27d9c10a04b4afa5ae1a0627f64120c4c9453cc47e084e128bd50420/metadata.json b/9c94f08b27d9c10a04b4afa5ae1a0627f64120c4c9453cc47e084e128bd50420/metadata.json
index cb1c245c4f15c82827d804750c622b67a93b2dc6..089ad0ca6a0c107375094f4a1399c1717ef3c625 100644
--- a/9c94f08b27d9c10a04b4afa5ae1a0627f64120c4c9453cc47e084e128bd50420/metadata.json
+++ b/9c94f08b27d9c10a04b4afa5ae1a0627f64120c4c9453cc47e084e128bd50420/metadata.json
@@ -162,5 +162,15 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "BioRxivsupplemental2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-728824/v1/832468407199eef8f3466fcc.pdf"
+        },
+        {
+            "title": "Lengetal.SupplementaryMaterialsNatComm.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-728824/v1/a01167b4e91f82a611848889.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/9e1e9b181095479ebbfc0321ac48be628dcaf8cfa00b4df2701650a85c2e7122/metadata.json b/9e1e9b181095479ebbfc0321ac48be628dcaf8cfa00b4df2701650a85c2e7122/metadata.json
index 67f18eeee73ab6d6b79c15dd8f81be6dbd825e31..f145a900e44e54fb6d3b579edb3084a8ed2a98ed 100644
--- a/9e1e9b181095479ebbfc0321ac48be628dcaf8cfa00b4df2701650a85c2e7122/metadata.json
+++ b/9e1e9b181095479ebbfc0321ac48be628dcaf8cfa00b4df2701650a85c2e7122/metadata.json
@@ -133,5 +133,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4963495/v1/8738f8844d55278ce8c98557.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a03678e51c1b39adbe92f90105a99a17cce18f1a77f3bf7b7da77e0cfec07267/metadata.json b/a03678e51c1b39adbe92f90105a99a17cce18f1a77f3bf7b7da77e0cfec07267/metadata.json
index 32a700f9aa2882dc6e93d2d586bcc0bf63d5fa91..c19b933c9779e8e464a4a0780e4cca13cbeb7b48 100644
--- a/a03678e51c1b39adbe92f90105a99a17cce18f1a77f3bf7b7da77e0cfec07267/metadata.json
+++ b/a03678e51c1b39adbe92f90105a99a17cce18f1a77f3bf7b7da77e0cfec07267/metadata.json
@@ -211,5 +211,27 @@
             "section_text": "Communications Biology (2025)\n\nThe EMBO Journal (2025)\n\nJournal of Biosciences (2025)\n\nActa Neuropathologica Communications (2024)\n\nJournal of Neuroinflammation (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "RESTsupplementalsubmit.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-102518/v1/463982c93474d384f0daed0e.pdf"
+        },
+        {
+            "title": "SupplementalTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-102518/v1/47c39d33f49981a84e54836d.xlsx"
+        },
+        {
+            "title": "SupplementalTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-102518/v1/f6d929e3a0165b33baab5837.xlsx"
+        },
+        {
+            "title": "SupplementalTable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-102518/v1/319f0704d5925f2e147cc3c4.xlsx"
+        },
+        {
+            "title": "SupplementalTable4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-102518/v1/13927d130dabba37abc38c5d.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a356df8f13972382c82c31950b73b6da0e0b52f19103123f6b7c2ad3d16fb0c3/metadata.json b/a356df8f13972382c82c31950b73b6da0e0b52f19103123f6b7c2ad3d16fb0c3/metadata.json
index 7ced37149500592fbba176a11ea4884361ad32ad..f61669550c5108c6bf11d2f76315ba552ab0d37a 100644
--- a/a356df8f13972382c82c31950b73b6da0e0b52f19103123f6b7c2ad3d16fb0c3/metadata.json
+++ b/a356df8f13972382c82c31950b73b6da0e0b52f19103123f6b7c2ad3d16fb0c3/metadata.json
@@ -201,5 +201,27 @@
             "section_text": "European Journal of Medical Research (2025)\n\nExperimental Hematology & Oncology (2025)\n\nCancer Cell International (2025)\n\nNature Cancer (2025)\n\nScientific Reports (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable3.csv",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1198158/v1/0f6dbd4505234dd089b7b606.csv"
+        },
+        {
+            "title": "SupplementaryTable4.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1198158/v1/6e4eceb73c98f62165fdc831.pdf"
+        },
+        {
+            "title": "SupplementaryTables1and2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1198158/v1/82c2e6643043f078a97568c8.xlsx"
+        },
+        {
+            "title": "SupplementraryDataset1GSEAMDSC.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1198158/v1/b82f4488d4c94163c20fea36.xlsx"
+        },
+        {
+            "title": "SupplementraryDataset2GSEATAMs.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1198158/v1/db0c14c5068c1f6eb6baf0c2.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a3b85b67f9321a4530b60ff6cfe1ab0a84067204fc9e97aa5fdcb2b4121daa60/metadata.json b/a3b85b67f9321a4530b60ff6cfe1ab0a84067204fc9e97aa5fdcb2b4121daa60/metadata.json
index 9003925085007c131fc9c94affd61be5644b3f9c..94cc35e8ed963703e2f2947458d950c167ccf4dd 100644
--- a/a3b85b67f9321a4530b60ff6cfe1ab0a84067204fc9e97aa5fdcb2b4121daa60/metadata.json
+++ b/a3b85b67f9321a4530b60ff6cfe1ab0a84067204fc9e97aa5fdcb2b4121daa60/metadata.json
@@ -219,5 +219,23 @@
             "section_text": "Nature Genetics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5187157/v1/7f6e320d1ef33075841e985f.pdf"
+        },
+        {
+            "title": "SupplementaryNotes.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5187157/v1/b4954a44c885f3a61b025f7e.pdf"
+        },
+        {
+            "title": "SupplementaryTables.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5187157/v1/6bf51961eb56e93ab8109373.xlsx"
+        },
+        {
+            "title": "Tables.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5187157/v1/65aec583826ff938fcd8dcda.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a42b23600537fd23c88e5370b65f268fab4924233bc8334a78821c082fc84d54/metadata.json b/a42b23600537fd23c88e5370b65f268fab4924233bc8334a78821c082fc84d54/metadata.json
index b99ca2f07825912513e9c5d19897a0591b1170d1..1f4156764583b959fb8d9690b80f1cb706815f53 100644
--- a/a42b23600537fd23c88e5370b65f268fab4924233bc8334a78821c082fc84d54/metadata.json
+++ b/a42b23600537fd23c88e5370b65f268fab4924233bc8334a78821c082fc84d54/metadata.json
@@ -243,5 +243,47 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NMICROBIOL24051349ASOM.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/56f61b67b78b53538a1f7a86.pdf"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/bca1e4ad785f2ffb0d255d3a.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/171638da7d946ca83689c247.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/5835a214ca5b2893f389a6df.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/f558e550b686119fc262cf14.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData5.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/7f88d741890db26aa261d64e.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData6.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/abf63a987d925f2850e7e8cc.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData7.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/d6a14209101d9590d151ea9f.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData8.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/2aba4be6c359c797178e98f7.xlsx"
+        },
+        {
+            "title": "NMICROBIOL24051349ASupplementaryData9.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4502330/v1/27399650bca3dc2629ff9317.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a4b1b42944845a84273f93368034ae1d90b9eca8dbd65452e71d9dbc8c52a1f9/metadata.json b/a4b1b42944845a84273f93368034ae1d90b9eca8dbd65452e71d9dbc8c52a1f9/metadata.json
index 4ccee2aeecb6bf10da5a480465b24d766a15f20c..3e338093fc184cfc19da30d1391044a71f8a074b 100644
--- a/a4b1b42944845a84273f93368034ae1d90b9eca8dbd65452e71d9dbc8c52a1f9/metadata.json
+++ b/a4b1b42944845a84273f93368034ae1d90b9eca8dbd65452e71d9dbc8c52a1f9/metadata.json
@@ -151,5 +151,19 @@
             "section_text": "BMC Complementary Medicine and Therapies (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Ld22A1tablesfinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3185204/v1/0212df238fc3c5519a863cd6.pdf"
+        },
+        {
+            "title": "Scheme1.png",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3185204/v1/41352711d519a273f6c4f6bd.png"
+        },
+        {
+            "title": "Ld22A1supplementalfiguresfinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3185204/v1/2d92b21af54c7956a08f31cd.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a6e157cfb42873a916f932d7c04bac38670341427e95d82fc0c39c9863e5a218/metadata.json b/a6e157cfb42873a916f932d7c04bac38670341427e95d82fc0c39c9863e5a218/metadata.json
index 9f1fbf1a6b1553b7bbabbf0f978e57d422e85ff7..cb4bbd27d118ee95c081da0f04108cd126bed654 100644
--- a/a6e157cfb42873a916f932d7c04bac38670341427e95d82fc0c39c9863e5a218/metadata.json
+++ b/a6e157cfb42873a916f932d7c04bac38670341427e95d82fc0c39c9863e5a218/metadata.json
@@ -174,5 +174,11 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TDNHBSupplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1048207/v1/7d28bfac69b6c192fde222a3.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a6e682bb0ef065dedd159ded971a70df6a793b5f752e458a2de87e10223513cf/metadata.json b/a6e682bb0ef065dedd159ded971a70df6a793b5f752e458a2de87e10223513cf/metadata.json
index 83957599ee2e2ad7470d612977405f81dc1974e5..d6d6fc77a94aefe4695d44b7c504ec12004f68be 100644
--- a/a6e682bb0ef065dedd159ded971a70df6a793b5f752e458a2de87e10223513cf/metadata.json
+++ b/a6e682bb0ef065dedd159ded971a70df6a793b5f752e458a2de87e10223513cf/metadata.json
@@ -182,5 +182,39 @@
             "section_text": "Rare Metals (2025)\n\nNano Research (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "video4.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/be4741c2b947919417ea20a5.mp4"
+        },
+        {
+            "title": "EDTNCommunSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/7601909c550075bae770b1e5.pdf"
+        },
+        {
+            "title": "video5.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/47c03436a9d65bdf6be48282.mp4"
+        },
+        {
+            "title": "video3.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/f4c3deeb7e4a10e9d3d11154.mp4"
+        },
+        {
+            "title": "video1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/562580f5a384d79f25f9c407.mp4"
+        },
+        {
+            "title": "video2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/2d210b8c7a7e3ed4178a3cc1.mp4"
+        },
+        {
+            "title": "video7.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/2752b9af6af13cbdcb6e74c6.mp4"
+        },
+        {
+            "title": "video6.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1592209/v1/1197d77220385c35276d8a90.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a846d5a9f9885ad1771e43abef8598278e55bf764450fa2205013d62e578183e/metadata.json b/a846d5a9f9885ad1771e43abef8598278e55bf764450fa2205013d62e578183e/metadata.json
index bb7f16770539dfe8cc8a542e01e531114e20ecb6..f68ca085fef79204cffdceec600d1cc89058dae3 100644
--- a/a846d5a9f9885ad1771e43abef8598278e55bf764450fa2205013d62e578183e/metadata.json
+++ b/a846d5a9f9885ad1771e43abef8598278e55bf764450fa2205013d62e578183e/metadata.json
@@ -155,5 +155,11 @@
             "section_text": "Advanced Fiber Materials (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtendedData.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3882851/v1/766a94d0e416c63ed5c87969.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a8a3e41f924b7a8b28d14a49a3cebcee0b5f265025a1cd23b918a6443b3c394b/metadata.json b/a8a3e41f924b7a8b28d14a49a3cebcee0b5f265025a1cd23b918a6443b3c394b/metadata.json
index 2a1a7e9c08bc8ec378c97b6ff618d104389b3ff0..77fec6a903cdce1dfe602945ca243cf61ac12e4a 100644
--- a/a8a3e41f924b7a8b28d14a49a3cebcee0b5f265025a1cd23b918a6443b3c394b/metadata.json
+++ b/a8a3e41f924b7a8b28d14a49a3cebcee0b5f265025a1cd23b918a6443b3c394b/metadata.json
@@ -165,5 +165,15 @@
             "section_text": "Experimental Hematology & Oncology (2025)\n\nBiomarker Research (2025)\n\nOncogene (2025)\n\nNature Reviews Bioengineering (2025)\n\nNature Cardiovascular Research (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "HsuetalSupplementaldataonly31822SA.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1451724/v1/ac58f1017eddc4c1c6d97a3a.pdf"
+        },
+        {
+            "title": "nrreportingsummaryforNCOMMS2210745T.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1451724/v1/436aa7995b35a7795548e17d.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a910475df1d259d9488446dd084b8e034955b01c296db06fac819551086648af/metadata.json b/a910475df1d259d9488446dd084b8e034955b01c296db06fac819551086648af/metadata.json
index e5d87085bbd8a51c6a874f6dd63e95749fc8596e..ddf899b3a241eacc587aa423279b298fb179cf4e 100644
--- a/a910475df1d259d9488446dd084b8e034955b01c296db06fac819551086648af/metadata.json
+++ b/a910475df1d259d9488446dd084b8e034955b01c296db06fac819551086648af/metadata.json
@@ -160,5 +160,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "JohansenAVX420Supplemental.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3485987/v1/80ed2266fc3d3944226abd3c.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/a94e2a62a18f7c3df96abf794bf48e4d519e1d5f7adb62cdd152250f97631314/metadata.json b/a94e2a62a18f7c3df96abf794bf48e4d519e1d5f7adb62cdd152250f97631314/metadata.json
index 157e0e7968289e50af9dbd70963052d62e5e1a45..23eff5bbdc37ed5bee375c6489b96f65318c9d01 100644
--- a/a94e2a62a18f7c3df96abf794bf48e4d519e1d5f7adb62cdd152250f97631314/metadata.json
+++ b/a94e2a62a18f7c3df96abf794bf48e4d519e1d5f7adb62cdd152250f97631314/metadata.json
@@ -131,5 +131,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supportinginformation.doc",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5912729/v1/0302916a2e0a06a6c7524da1.doc"
+        }
     ]
 }
\ No newline at end of file
diff --git a/aa1848b721c6e63a9274ae2b17cc4960f163b8ebf9ea8a8e155b5e55ae7e08f6/metadata.json b/aa1848b721c6e63a9274ae2b17cc4960f163b8ebf9ea8a8e155b5e55ae7e08f6/metadata.json
index 2ffc9460ad89f3921d415b4f2fe6de55d8b83867..e9968cea0b5661bb7ed1560cd90a38cc0fa572bc 100644
--- a/aa1848b721c6e63a9274ae2b17cc4960f163b8ebf9ea8a8e155b5e55ae7e08f6/metadata.json
+++ b/aa1848b721c6e63a9274ae2b17cc4960f163b8ebf9ea8a8e155b5e55ae7e08f6/metadata.json
@@ -128,5 +128,11 @@
             "section_text": "Nature Catalysis (2025)\n\nNature Communications (2025)\n\nJournal of Nanoparticle Research (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementalInformationNC.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2709219/v1/dac0814cd74100831b3c1dd2.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/aa4f2e4715595cd447d1ebc4774badc3bda2da137f78bb4bc98cfbbd7646bb2f/metadata.json b/aa4f2e4715595cd447d1ebc4774badc3bda2da137f78bb4bc98cfbbd7646bb2f/metadata.json
index f367c89d7156ee324bee3240e8d8a944711e4679..68ea32a088f9022c56c3b85f0c0cb183fc912f4b 100644
--- a/aa4f2e4715595cd447d1ebc4774badc3bda2da137f78bb4bc98cfbbd7646bb2f/metadata.json
+++ b/aa4f2e4715595cd447d1ebc4774badc3bda2da137f78bb4bc98cfbbd7646bb2f/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Water (2025)\n\nNature Communications (2025)\n\nNature Sustainability (2025)\n\nNature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupportingInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3123974/v1/3fbf3ddf90fb1524e0178658.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/aadf2e1216f94b808e4b62d4c3dd6b5c5d63a0d34c512fd58d3723f34bc8f7ea/metadata.json b/aadf2e1216f94b808e4b62d4c3dd6b5c5d63a0d34c512fd58d3723f34bc8f7ea/metadata.json
index d8c10892c49185e6584a848057f16c2e9cc9b83d..83214881be4af15f481757119560c060fc0c796c 100644
--- a/aadf2e1216f94b808e4b62d4c3dd6b5c5d63a0d34c512fd58d3723f34bc8f7ea/metadata.json
+++ b/aadf2e1216f94b808e4b62d4c3dd6b5c5d63a0d34c512fd58d3723f34bc8f7ea/metadata.json
@@ -151,5 +151,11 @@
             "section_text": "Space Science Reviews (2025)\n\nCommunications Physics (2024)\n\nReviews of Modern Plasma Physics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "GUIDEDOA2200435reportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1423536/v1/47afe31a6bf5deccc97602fb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ac993318e6c6ee8ec3c245bacff20a4b7bb502aea6e7f12ef0299898f7a7a4b8/metadata.json b/ac993318e6c6ee8ec3c245bacff20a4b7bb502aea6e7f12ef0299898f7a7a4b8/metadata.json
index 2a47db0885a6e876a81b264fabbba8a2f5e5e673..9c4e7f4b1cfc4599db7c80bdbe2bb30dba89c379 100644
--- a/ac993318e6c6ee8ec3c245bacff20a4b7bb502aea6e7f12ef0299898f7a7a4b8/metadata.json
+++ b/ac993318e6c6ee8ec3c245bacff20a4b7bb502aea6e7f12ef0299898f7a7a4b8/metadata.json
@@ -156,5 +156,11 @@
             "section_text": "Scientific Reports (2025)\n\nIn Silico Pharmacology (2025)\n\nIn Silico Pharmacology (2025)\n\nMolecular Diversity (2025)\n\nMolecular Diversity (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NCOMMS223929302RS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2108355/v1/cbf40a29b903a7464c98e7e7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/acef342d0c08323c0d92369bc6af0300840e377f70fa1e06a7a311245ad01df9/metadata.json b/acef342d0c08323c0d92369bc6af0300840e377f70fa1e06a7a311245ad01df9/metadata.json
index c2a1656926d1b0b8a96d24643ffd0bb7065f06d0..c5a322cb91f4e8c36ab3c169cd5f8139f8b3194e 100644
--- a/acef342d0c08323c0d92369bc6af0300840e377f70fa1e06a7a311245ad01df9/metadata.json
+++ b/acef342d0c08323c0d92369bc6af0300840e377f70fa1e06a7a311245ad01df9/metadata.json
@@ -160,5 +160,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementarymaterials.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3937453/v1/4e45dca3dc116a74425c7a15.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ad1ae1d2d2ff0a5c909c31d36a38e1f3fb83bfd65a3b0ee30a7e346006a3969e/metadata.json b/ad1ae1d2d2ff0a5c909c31d36a38e1f3fb83bfd65a3b0ee30a7e346006a3969e/metadata.json
index 3ea8d905eda5227f82399dc814ac2121e54dbbd8..8555317c5e299b48108f9bb3765b46266fc6c681 100644
--- a/ad1ae1d2d2ff0a5c909c31d36a38e1f3fb83bfd65a3b0ee30a7e346006a3969e/metadata.json
+++ b/ad1ae1d2d2ff0a5c909c31d36a38e1f3fb83bfd65a3b0ee30a7e346006a3969e/metadata.json
@@ -139,5 +139,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupportingInformation20240402final.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4205289/v1/89043fcf861aa181aed4e32f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ad5b0ff769f7f983c9bae9d8e0182747785cad93c8e142e189c601c68ecae456/metadata.json b/ad5b0ff769f7f983c9bae9d8e0182747785cad93c8e142e189c601c68ecae456/metadata.json
index 39ed60f0b42d96d1eb0e36f12d24e8dd4a2d6716..1c3edc49725f512642696f32fe70d46b11671e28 100644
--- a/ad5b0ff769f7f983c9bae9d8e0182747785cad93c8e142e189c601c68ecae456/metadata.json
+++ b/ad5b0ff769f7f983c9bae9d8e0182747785cad93c8e142e189c601c68ecae456/metadata.json
@@ -144,5 +144,11 @@
             "section_text": "npj Quantum Materials (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SungSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3150622/v1/a0567ceb789eda446882493a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ae146ffa8168716e0bd86233daeeabd69c73919871c3d22b2615b5b91b2e7719/metadata.json b/ae146ffa8168716e0bd86233daeeabd69c73919871c3d22b2615b5b91b2e7719/metadata.json
index e67a71938168bdc7ecbcffe7e9a983b18d5a700b..12760ec0ad6dbbe7eb4d89a08190d109eb730a0f 100644
--- a/ae146ffa8168716e0bd86233daeeabd69c73919871c3d22b2615b5b91b2e7719/metadata.json
+++ b/ae146ffa8168716e0bd86233daeeabd69c73919871c3d22b2615b5b91b2e7719/metadata.json
@@ -173,5 +173,11 @@
             "section_text": "Journal of Cheminformatics (2025)\n\nBioNanoScience (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplmentary.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3995849/v1/ca546f69970a1e6a042a8df4.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/afbe78363395291ed6b971d3c844385c0748a18a228ea31019037445dfdfff63/metadata.json b/afbe78363395291ed6b971d3c844385c0748a18a228ea31019037445dfdfff63/metadata.json
index 1fa3bf73a194298af96250e3296dae3b254cf258..db6ea91d1d85c3d970fd16dfe1b63e5f517aec50 100644
--- a/afbe78363395291ed6b971d3c844385c0748a18a228ea31019037445dfdfff63/metadata.json
+++ b/afbe78363395291ed6b971d3c844385c0748a18a228ea31019037445dfdfff63/metadata.json
@@ -144,5 +144,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "DriversofFireRisktoStructuresinWUIsupplemental.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5776626/v1/cf40546af20f71f042cbeb80.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b0a50a0eb4fffe742961b39b88d5479adf990d97c3819564bb4712d87963b34c/metadata.json b/b0a50a0eb4fffe742961b39b88d5479adf990d97c3819564bb4712d87963b34c/metadata.json
index 6725b49e3a01042fd08b3e2a5f46f526cf80639a..5673b3eb926ad444a91992d8cc1b3bf38b882faf 100644
--- a/b0a50a0eb4fffe742961b39b88d5479adf990d97c3819564bb4712d87963b34c/metadata.json
+++ b/b0a50a0eb4fffe742961b39b88d5479adf990d97c3819564bb4712d87963b34c/metadata.json
@@ -171,5 +171,15 @@
             "section_text": "Nature Microbiology (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Dataset1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-966555/v1/f935ddbbf3ce1d212c69ee6e.xlsx"
+        },
+        {
+            "title": "Jaitlyetal.supplenaturecom.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-966555/v1/6675008ea1d0b39a28258b3c.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b0c27dce1a12ed45e5ca5a8a74d0eba640bc749d138724e5456c991f5b1307c8/metadata.json b/b0c27dce1a12ed45e5ca5a8a74d0eba640bc749d138724e5456c991f5b1307c8/metadata.json
index 5a09beefebe1b13884837b9c26931572d1bd3099..c14520b81690cf1ef0ec600974fab914256984ba 100644
--- a/b0c27dce1a12ed45e5ca5a8a74d0eba640bc749d138724e5456c991f5b1307c8/metadata.json
+++ b/b0c27dce1a12ed45e5ca5a8a74d0eba640bc749d138724e5456c991f5b1307c8/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Nature Communications (2025)\n\nScience China Chemistry (2025)\n\nCatalysis Letters (2025)\n\nRare Metals (2025)\n\nScience China Chemistry (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1599351/v1/4ca2b90cbf8cab1b8ac0fcea.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b1105cfec1202c9eb94f66673ebbd8642257ff408a3ffdc812243170f66c2be1/metadata.json b/b1105cfec1202c9eb94f66673ebbd8642257ff408a3ffdc812243170f66c2be1/metadata.json
index fa588649cc08368c52657f3bf6020cb164756857..dd95186ae0135e898df3d8a990616d79016fcec7 100644
--- a/b1105cfec1202c9eb94f66673ebbd8642257ff408a3ffdc812243170f66c2be1/metadata.json
+++ b/b1105cfec1202c9eb94f66673ebbd8642257ff408a3ffdc812243170f66c2be1/metadata.json
@@ -168,5 +168,23 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2025)\n\nLight: Science & Applications (2025)\n\nLight: Science & Applications (2025)\n\nLight: Science & Applications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryEH24.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-332018/v1/6f02945de274d40fa9343ab0.pdf"
+        },
+        {
+            "title": "SupVideo1.gif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-332018/v1/ff747d40b60e9d4fdf807955.gif"
+        },
+        {
+            "title": "SupVideo2.gif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-332018/v1/bbca50cc0c9b45bd92d000a7.gif"
+        },
+        {
+            "title": "SupVideo3.gif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-332018/v1/fb5e942ee48978f5653bbd3f.gif"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b1988a99d059e742e553e40aec0483502940237cd6dd017a5a758045e3a8d650/metadata.json b/b1988a99d059e742e553e40aec0483502940237cd6dd017a5a758045e3a8d650/metadata.json
index 243b3f9d58b5b6339658f881e5fa9f471efb2466..d08f777ba4363b8506b6b890457169b7f3b0b84a 100644
--- a/b1988a99d059e742e553e40aec0483502940237cd6dd017a5a758045e3a8d650/metadata.json
+++ b/b1988a99d059e742e553e40aec0483502940237cd6dd017a5a758045e3a8d650/metadata.json
@@ -162,5 +162,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SwiftSupplFig6A.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3169914/v1/6b4a657185c76dd883847544.avi"
+        },
+        {
+            "title": "SwiftSupplFig6B.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3169914/v1/ebc0e4718e8aa696423d9bef.avi"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b1b52bfe8a35fbe196330a14adb472d090fa41f7e5076b491773f66d22196fe9/metadata.json b/b1b52bfe8a35fbe196330a14adb472d090fa41f7e5076b491773f66d22196fe9/metadata.json
index 1a65740ccc7e04b5ba9e96938ba9d86aeffdf80a..d5f3d03598555b48a0c0e2ddf5570a60c2a4542f 100644
--- a/b1b52bfe8a35fbe196330a14adb472d090fa41f7e5076b491773f66d22196fe9/metadata.json
+++ b/b1b52bfe8a35fbe196330a14adb472d090fa41f7e5076b491773f66d22196fe9/metadata.json
@@ -134,5 +134,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5274115/v1/a2788f3a50bbcc1c1e2ed87c.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b251cb9b68cfd7c5eb8184a2ee87359838adf9bda75dbbd91de5b28e78ac1a25/metadata.json b/b251cb9b68cfd7c5eb8184a2ee87359838adf9bda75dbbd91de5b28e78ac1a25/metadata.json
index ca2818370ff6f1a3a160967403a89d395a10b48e..5512ee3e9d8a2ec3bc1289b254f22ac8eda628ea 100644
--- a/b251cb9b68cfd7c5eb8184a2ee87359838adf9bda75dbbd91de5b28e78ac1a25/metadata.json
+++ b/b251cb9b68cfd7c5eb8184a2ee87359838adf9bda75dbbd91de5b28e78ac1a25/metadata.json
@@ -160,5 +160,15 @@
             "section_text": "Journal of Nanobiotechnology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "9ASGBtaNeovalreportfullP1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4457195/v1/90ebce6ff5fe7c6c1d321921.pdf"
+        },
+        {
+            "title": "MovieS1traj541007fullstep20white.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4457195/v1/80d9ded9150b39108fe91f18.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b2696dfe00d3fc96f7df96d0e7285a41382bab624566a236017b15413472458f/metadata.json b/b2696dfe00d3fc96f7df96d0e7285a41382bab624566a236017b15413472458f/metadata.json
index a208bfab2dc5da029920ff78bbbffefb2dd0d61c..30668b9c23f4e444388dbb84b95863c3de823d49 100644
--- a/b2696dfe00d3fc96f7df96d0e7285a41382bab624566a236017b15413472458f/metadata.json
+++ b/b2696dfe00d3fc96f7df96d0e7285a41382bab624566a236017b15413472458f/metadata.json
@@ -141,5 +141,19 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupportingInformationNCdbr.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1443799/v1/83660e89b1f72d5ca7c74829.pdf"
+        },
+        {
+            "title": "SupplementaryvideoI.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1443799/v1/545094d9d4d358367cf63d74.mp4"
+        },
+        {
+            "title": "SupplementaryvideoII.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1443799/v1/869c1e4b19b6f2fb528a7bb5.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b3a21815fc5fa8e7c39f0e5cfc096db93c0e7dec8f3d8fc214234c874fa62efe/metadata.json b/b3a21815fc5fa8e7c39f0e5cfc096db93c0e7dec8f3d8fc214234c874fa62efe/metadata.json
index f6ea2920b4862637dc4c4e74bff3899de1d1e642..7e971e01aecb896748cdfc635ce51705714faa0f 100644
--- a/b3a21815fc5fa8e7c39f0e5cfc096db93c0e7dec8f3d8fc214234c874fa62efe/metadata.json
+++ b/b3a21815fc5fa8e7c39f0e5cfc096db93c0e7dec8f3d8fc214234c874fa62efe/metadata.json
@@ -180,5 +180,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SINatMaterglassMOF20230509.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2922761/v1/c289c75fa8e4a803eb31e0fe.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b3fb9145f0aa1ea90133bd54a3b4c9195977c2f8dc7fba562e2b6fbf7a6ea38a/metadata.json b/b3fb9145f0aa1ea90133bd54a3b4c9195977c2f8dc7fba562e2b6fbf7a6ea38a/metadata.json
index 8ad6887e7ed4e5b0e291e848b14a257cd89781b4..25d75a7fd4a59ec27362f6d5d4ea600549898c92 100644
--- a/b3fb9145f0aa1ea90133bd54a3b4c9195977c2f8dc7fba562e2b6fbf7a6ea38a/metadata.json
+++ b/b3fb9145f0aa1ea90133bd54a3b4c9195977c2f8dc7fba562e2b6fbf7a6ea38a/metadata.json
@@ -203,5 +203,31 @@
             "section_text": "",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFigureS1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/8f28512a5469d038444ff67c.pdf"
+        },
+        {
+            "title": "SupplementaryFigureS2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/f236eb91a52e7493ffb2c122.pdf"
+        },
+        {
+            "title": "SupplementaryFigureS3.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/b2daace3dcdc7c5d49f5b09d.pdf"
+        },
+        {
+            "title": "SupplementaryTableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/9db52acedd1c994f24d11e47.xlsx"
+        },
+        {
+            "title": "SupplementaryTableS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/95c467c476626f7ad363541c.xlsx"
+        },
+        {
+            "title": "SupplementaryTableS3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2921471/v1/0640e4eb6fd115c4308e032b.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b46b8d2eb3030c20fb151d48a71b46752fa49c1c102bc842028043ad26768782/metadata.json b/b46b8d2eb3030c20fb151d48a71b46752fa49c1c102bc842028043ad26768782/metadata.json
index 8e786fa0b6c6139e832cbd766e5c379876beb255..0fa502ddbe0370b841e49d6e110674e30a8488ab 100644
--- a/b46b8d2eb3030c20fb151d48a71b46752fa49c1c102bc842028043ad26768782/metadata.json
+++ b/b46b8d2eb3030c20fb151d48a71b46752fa49c1c102bc842028043ad26768782/metadata.json
@@ -137,5 +137,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "CoFTsynthesisSupplementaryMaterials.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3970719/v1/49b2fb85a6d4c61f1e2b714b.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b638549dae6f02702fb2f64e39718479108ac2c8534de8111f51c841cd85e594/metadata.json b/b638549dae6f02702fb2f64e39718479108ac2c8534de8111f51c841cd85e594/metadata.json
index e0464f1e65696e2f00140b2137d0b9a3dbe676b1..41d24b04357ee5dfa68d45cf0c4bbb63b3b69a90 100644
--- a/b638549dae6f02702fb2f64e39718479108ac2c8534de8111f51c841cd85e594/metadata.json
+++ b/b638549dae6f02702fb2f64e39718479108ac2c8534de8111f51c841cd85e594/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementaryinformationv2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3929576/v1/11770066e368f7857d59e1f5.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b756b9cd05ab0bbbf409fb4eca5fbec37a72b1bb606fe02ae7d082c579298614/metadata.json b/b756b9cd05ab0bbbf409fb4eca5fbec37a72b1bb606fe02ae7d082c579298614/metadata.json
index 3f95c16f65ffbccdace16e1b0024f4045276b38e..49d1b80503df4c51ad17d42c0d5ff17716b6f5b2 100644
--- a/b756b9cd05ab0bbbf409fb4eca5fbec37a72b1bb606fe02ae7d082c579298614/metadata.json
+++ b/b756b9cd05ab0bbbf409fb4eca5fbec37a72b1bb606fe02ae7d082c579298614/metadata.json
@@ -136,5 +136,11 @@
             "section_text": "Communications Earth & Environment (2025)\n\nBulletin of Volcanology (2025)\n\nCommunications Earth & Environment (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTablesNATGEOL.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1287595/v1/ba4484f85e92de3ebf567530.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b7bd15c5e1107b3d2c6544c53e4e3f5f7910cb81077f69961bbb556b31000887/metadata.json b/b7bd15c5e1107b3d2c6544c53e4e3f5f7910cb81077f69961bbb556b31000887/metadata.json
index 167f63173d57924dd6c7487ba5405655651f3de4..b44802a68e3f12662f6f5f11fac8bfdc0e8dd734 100644
--- a/b7bd15c5e1107b3d2c6544c53e4e3f5f7910cb81077f69961bbb556b31000887/metadata.json
+++ b/b7bd15c5e1107b3d2c6544c53e4e3f5f7910cb81077f69961bbb556b31000887/metadata.json
@@ -129,5 +129,11 @@
             "section_text": "Nature Communications (2025)\n\nnpj Quantum Materials (2025)\n\nCommunications Physics (2025)\n\nNature Communications (2025)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformationAV3Sb5.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2018004/v1/5d001dac330833363ab00df9.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b7f5c1260448beb30cd74be2874649005e72d89bc07294aa5e23e044e8a38921/metadata.json b/b7f5c1260448beb30cd74be2874649005e72d89bc07294aa5e23e044e8a38921/metadata.json
index df7dc7a9ca74dcd0a85dda013bdeca4b6fe31ece..a36b8465f47446d69b3ae0d1aa2604c5d83fa828 100644
--- a/b7f5c1260448beb30cd74be2874649005e72d89bc07294aa5e23e044e8a38921/metadata.json
+++ b/b7f5c1260448beb30cd74be2874649005e72d89bc07294aa5e23e044e8a38921/metadata.json
@@ -130,5 +130,11 @@
             "section_text": "Nature Photonics (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PMLRTDSup20210919.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-919266/v1/6ff4b7ae752faa9e56f7921b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b84e264ea1afb49e4b74c2a05286ee496ffda2552760a607c9081dbb204f697c/metadata.json b/b84e264ea1afb49e4b74c2a05286ee496ffda2552760a607c9081dbb204f697c/metadata.json
index f16ea2d26895c8611b91d9b9a8edf93ae19ce727..d34831b50771cdaf524682c6c0c9a15456ae9504 100644
--- a/b84e264ea1afb49e4b74c2a05286ee496ffda2552760a607c9081dbb204f697c/metadata.json
+++ b/b84e264ea1afb49e4b74c2a05286ee496ffda2552760a607c9081dbb204f697c/metadata.json
@@ -150,5 +150,11 @@
             "section_text": "Science China Materials (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-118565/v1/75a99aafb85b9519ea40caeb.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/b97345618b1744333cf081a8e012a0967d0c99fbb22fb2d942c12d27edfd4af2/metadata.json b/b97345618b1744333cf081a8e012a0967d0c99fbb22fb2d942c12d27edfd4af2/metadata.json
index 558dff30c64350353f49fb824d154107b3ba751e..1e8c32ddb0c8fede28fe2e6d3a0c6c65baec2094 100644
--- a/b97345618b1744333cf081a8e012a0967d0c99fbb22fb2d942c12d27edfd4af2/metadata.json
+++ b/b97345618b1744333cf081a8e012a0967d0c99fbb22fb2d942c12d27edfd4af2/metadata.json
@@ -144,5 +144,11 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PSDarticlesupplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3792254/v1/a73399d9aed78a2dc8e3b718.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/bb2ed326eb0d02d342854b569aa19ec6e08b29985e9280fd30eb39b3f88db529/metadata.json b/bb2ed326eb0d02d342854b569aa19ec6e08b29985e9280fd30eb39b3f88db529/metadata.json
index a43f0dd6e4607958d46a84083b9eaa08b4a87d2c..9e2f9c9e944f05390d48fe8093099479df045ad0 100644
--- a/bb2ed326eb0d02d342854b569aa19ec6e08b29985e9280fd30eb39b3f88db529/metadata.json
+++ b/bb2ed326eb0d02d342854b569aa19ec6e08b29985e9280fd30eb39b3f88db529/metadata.json
@@ -184,5 +184,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "05SupplementaryTables.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3289295/v1/44278070f7936dcc43d7a63f.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/bcac30b1d07ece7ead3e7f4fb623d621f416cd275685f939bacd464f52b122a3/metadata.json b/bcac30b1d07ece7ead3e7f4fb623d621f416cd275685f939bacd464f52b122a3/metadata.json
index fec308394075b23216a8c5898983693cf1b7692b..905d2bd8bad62f5cd528e7318459a8b753bd7889 100644
--- a/bcac30b1d07ece7ead3e7f4fb623d621f416cd275685f939bacd464f52b122a3/metadata.json
+++ b/bcac30b1d07ece7ead3e7f4fb623d621f416cd275685f939bacd464f52b122a3/metadata.json
@@ -143,5 +143,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementalSmallAreaPopEstimates.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5059066/v1/307933085b1923a643879f83.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/bd5fcaa0dd2722734fc6541063d10530776561d4b77c54c8e69600c829212f6c/metadata.json b/bd5fcaa0dd2722734fc6541063d10530776561d4b77c54c8e69600c829212f6c/metadata.json
index 6f5262c00fc1301075fde4675f84b29b53d69cef..c069967d92990d56b5acfdc23f66ad07266b070c 100644
--- a/bd5fcaa0dd2722734fc6541063d10530776561d4b77c54c8e69600c829212f6c/metadata.json
+++ b/bd5fcaa0dd2722734fc6541063d10530776561d4b77c54c8e69600c829212f6c/metadata.json
@@ -189,5 +189,31 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Chernyshev.etal.figures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/473ad7b1f0fa52d446cdb1f9.pdf"
+        },
+        {
+            "title": "Supplementarytable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/fb38d3c252eb49171ed45994.xlsx"
+        },
+        {
+            "title": "Supplementarytable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/8c2792c0ab4af16183c5d3ed.xlsx"
+        },
+        {
+            "title": "Supplementarytable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/196e5be39a3b37f91cc7e113.xlsx"
+        },
+        {
+            "title": "Supplementarytable4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/4041e7448af3ea930bb49829.xlsx"
+        },
+        {
+            "title": "nrreportingsummary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2231608/v1/a516ba31f15ac3460cd7fbcc.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/be83854bda4c545ebe808a0bea3b9cd8d8cbb7463066023fae24ef12259e20a1/metadata.json b/be83854bda4c545ebe808a0bea3b9cd8d8cbb7463066023fae24ef12259e20a1/metadata.json
index 341bd9d19bd98afa43d321457be8a3ebf0fc62a2..3a033bb638f31f078d591d78b99f8f7da767e6df 100644
--- a/be83854bda4c545ebe808a0bea3b9cd8d8cbb7463066023fae24ef12259e20a1/metadata.json
+++ b/be83854bda4c545ebe808a0bea3b9cd8d8cbb7463066023fae24ef12259e20a1/metadata.json
@@ -198,5 +198,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ExtDataFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4414130/v1/c990e51919d099336c28dc62.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/bf2c60cfebe796882a8061ba9814a0cb39590442fc80df7dced3cb1af489ccbb/metadata.json b/bf2c60cfebe796882a8061ba9814a0cb39590442fc80df7dced3cb1af489ccbb/metadata.json
index 0f3aae7032ad88bd7f03d224976414ed4096750a..36001980b2db0eb7177266183885651607d37461 100644
--- a/bf2c60cfebe796882a8061ba9814a0cb39590442fc80df7dced3cb1af489ccbb/metadata.json
+++ b/bf2c60cfebe796882a8061ba9814a0cb39590442fc80df7dced3cb1af489ccbb/metadata.json
@@ -167,5 +167,11 @@
             "section_text": "BMC Plant Biology (2025)\n\nNature Methods (2025)\n\nNature Reviews Bioengineering (2025)\n\nNature Reviews Molecular Cell Biology (2025)\n\nArtificial Intelligence Review (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3922651/v1/bc04f65cfe2f1246fbacbb9f.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c1765bad951de23d2cef1d75af0b24268f1aa9108e4933384968aa975747470f/metadata.json b/c1765bad951de23d2cef1d75af0b24268f1aa9108e4933384968aa975747470f/metadata.json
index 8f29ec63b2e271cee2efa02bc7501b1798b50ed7..fc6f50582027bd019ec1b02629100b6164e53dc6 100644
--- a/c1765bad951de23d2cef1d75af0b24268f1aa9108e4933384968aa975747470f/metadata.json
+++ b/c1765bad951de23d2cef1d75af0b24268f1aa9108e4933384968aa975747470f/metadata.json
@@ -142,5 +142,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5423769/v1/af54481e031fdd3bdb181941.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c1fb25a2109c014fceb48d55aaa3720e44cb2afc8633c236c41e56e71b446dbd/metadata.json b/c1fb25a2109c014fceb48d55aaa3720e44cb2afc8633c236c41e56e71b446dbd/metadata.json
index bcee86bec816d0197c0a069be357eda8e9c26478..41f8ea64ebc5a4ae7ebd9e85fdabc08e16f59e25 100644
--- a/c1fb25a2109c014fceb48d55aaa3720e44cb2afc8633c236c41e56e71b446dbd/metadata.json
+++ b/c1fb25a2109c014fceb48d55aaa3720e44cb2afc8633c236c41e56e71b446dbd/metadata.json
@@ -129,5 +129,11 @@
             "section_text": "Scientific Reports (2025)\n\nScience China Physics, Mechanics & Astronomy (2025)\n\nJournal of High Energy Physics (2025)\n\nJournal of High Energy Physics (2025)\n\nScience China Physics, Mechanics & Astronomy (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "blackholesm.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2029103/v1/57837c572120169cfade5e76.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c22fbaed1ab44b4c57c8b9f7ca571ed07f998166aea422b37f0775331fc45a15/metadata.json b/c22fbaed1ab44b4c57c8b9f7ca571ed07f998166aea422b37f0775331fc45a15/metadata.json
index b1f5be8a0ddcbbce8687edd2406f36537ba1a18b..a46d7616285bd9aa8a66ed4bf3f25ff30d0af866 100644
--- a/c22fbaed1ab44b4c57c8b9f7ca571ed07f998166aea422b37f0775331fc45a15/metadata.json
+++ b/c22fbaed1ab44b4c57c8b9f7ca571ed07f998166aea422b37f0775331fc45a15/metadata.json
@@ -154,5 +154,15 @@
             "section_text": "Nature Communications (2025)\n\nNature Communications (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TISAMIGOSSMR01v02.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1466534/v1/6db6975b9eb32f9e5c1b0869.pdf"
+        },
+        {
+            "title": "nreditorialpolicychecklist.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1466534/v1/dfbb68056436a11d839e28c1.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c3bfa2799de5b45a3a0c176eb8d38eb3ef4d013e88484859815e8446785ad2df/metadata.json b/c3bfa2799de5b45a3a0c176eb8d38eb3ef4d013e88484859815e8446785ad2df/metadata.json
index 728b8519265671d9d34dc5fa4b24ecddc68a90a9..03066d5d3448d17632f405b8d8cbe6bb17de5063 100644
--- a/c3bfa2799de5b45a3a0c176eb8d38eb3ef4d013e88484859815e8446785ad2df/metadata.json
+++ b/c3bfa2799de5b45a3a0c176eb8d38eb3ef4d013e88484859815e8446785ad2df/metadata.json
@@ -158,5 +158,11 @@
             "section_text": "Nature (2025)\n\nScientific Reports (2025)\n\nNature Immunology (2025)\n\nBMC Infectious Diseases (2025)\n\nBMC Infectious Diseases (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaldata1422021.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-241266/v1/80c8aa0f312921a49268407a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c3e7c762f18f881af09afec161986499b331bd0c821db69cfea8371c4f7ca680/metadata.json b/c3e7c762f18f881af09afec161986499b331bd0c821db69cfea8371c4f7ca680/metadata.json
index 254613d0e49938eba6196e7ca1438645815f4630..121e639f18f91f55cbc13f62e54ad2c49b5c474f 100644
--- a/c3e7c762f18f881af09afec161986499b331bd0c821db69cfea8371c4f7ca680/metadata.json
+++ b/c3e7c762f18f881af09afec161986499b331bd0c821db69cfea8371c4f7ca680/metadata.json
@@ -126,5 +126,19 @@
             "section_text": "Nature Communications (2025)\n\nCommunications Materials (2024)\n\nCommunications Materials (2024)\n\nNano Research (2024)\n\nNano Research (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NondefectiveHfUiO66.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2374720/v1/f2bbffcc98286cd10cd0a948.pdf"
+        },
+        {
+            "title": "reoHfUiO66.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2374720/v1/41ffa3a403d9a3ce8da6e5a6.pdf"
+        },
+        {
+            "title": "MartiGastaldoNatureChemsupplementaryinformationor.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2374720/v1/849f346c39040c6477e2bc20.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c3f02c61884421825dfd9ca5a9550fa09ae2ccd7f7566c4558d3182c951bea66/metadata.json b/c3f02c61884421825dfd9ca5a9550fa09ae2ccd7f7566c4558d3182c951bea66/metadata.json
index 2f40cfd3f1888d4e1442a11d5bd689af6b451256..5517377a69287dbbe81ce805ca1cf2950f3999b4 100644
--- a/c3f02c61884421825dfd9ca5a9550fa09ae2ccd7f7566c4558d3182c951bea66/metadata.json
+++ b/c3f02c61884421825dfd9ca5a9550fa09ae2ccd7f7566c4558d3182c951bea66/metadata.json
@@ -145,5 +145,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "OptimizedWeightProgrammingforAnalogueAISupplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1028668/v1/e80e2e36b57f74413c6ff5eb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c487850fa753db00bd2276c5614375412d4bfca25200521ebbb957b52c51e636/metadata.json b/c487850fa753db00bd2276c5614375412d4bfca25200521ebbb957b52c51e636/metadata.json
index 8e8fd23f511068d37f7eb810420ea4bfb4f1d947..2c8027f75582802b449e1590da79700a8b3b2cb3 100644
--- a/c487850fa753db00bd2276c5614375412d4bfca25200521ebbb957b52c51e636/metadata.json
+++ b/c487850fa753db00bd2276c5614375412d4bfca25200521ebbb957b52c51e636/metadata.json
@@ -152,5 +152,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4463391/v1/7673419692c0b118a1d7affb.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c552168ca484db50fd40b145e08ef5ed7ef46b0124aeb0f338dd865b58168594/metadata.json b/c552168ca484db50fd40b145e08ef5ed7ef46b0124aeb0f338dd865b58168594/metadata.json
index d4758cdba7210019452365dfe59bf57832ad9cf1..7ec08dfdf0c8ee5daecf9f4add347281c68208f8 100644
--- a/c552168ca484db50fd40b145e08ef5ed7ef46b0124aeb0f338dd865b58168594/metadata.json
+++ b/c552168ca484db50fd40b145e08ef5ed7ef46b0124aeb0f338dd865b58168594/metadata.json
@@ -127,5 +127,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ELBTSupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4671262/v1/129723189f212b777222f463.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c6cfdacf485c17ba2ff1247036212d130463f3c76efbb9db7eeae3cc6a0bde24/metadata.json b/c6cfdacf485c17ba2ff1247036212d130463f3c76efbb9db7eeae3cc6a0bde24/metadata.json
index 61cbef3cbde2fc378640bd0afc4c7b8a1756d6f6..39e12bda2852346d46f14d4037898f6c28f16a6c 100644
--- a/c6cfdacf485c17ba2ff1247036212d130463f3c76efbb9db7eeae3cc6a0bde24/metadata.json
+++ b/c6cfdacf485c17ba2ff1247036212d130463f3c76efbb9db7eeae3cc6a0bde24/metadata.json
@@ -146,5 +146,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5920918/v1/3ea1e49cd433edc1f4c0d120.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c7a3adbaf992197c2c8f575e5621503843972ccc88569f0102e86e914c9ae23b/metadata.json b/c7a3adbaf992197c2c8f575e5621503843972ccc88569f0102e86e914c9ae23b/metadata.json
index 95d37b1e15aed46d898633c62400a511568d138e..e0bca5c96beaebe64bd9919f91e4c4a0e38c6bf6 100644
--- a/c7a3adbaf992197c2c8f575e5621503843972ccc88569f0102e86e914c9ae23b/metadata.json
+++ b/c7a3adbaf992197c2c8f575e5621503843972ccc88569f0102e86e914c9ae23b/metadata.json
@@ -186,5 +186,15 @@
             "section_text": "Health Nanotechnology (2025)\n\nJournal of Analytical Science and Technology (2025)\n\nCommunications Medicine (2025)\n\nArchives of Microbiology (2025)\n\nScience China Chemistry (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "AutoCARSI.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2586294/v1/6fb989e2460b18e54e7b3484.docx"
+        },
+        {
+            "title": "nrreportingsummaryYLAutoCAR.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2586294/v1/592b9aeb77e48c274500a850.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c7bcbd447683a01536c22ee1e4ce1d0bbb3faf5e2959904709afaeddb2683d74/metadata.json b/c7bcbd447683a01536c22ee1e4ce1d0bbb3faf5e2959904709afaeddb2683d74/metadata.json
index 49d7cb418d5cff18469f736361388d02ac88032d..7b3800d68f775ac3ba7f380df4d1e3259b1ea19b 100644
--- a/c7bcbd447683a01536c22ee1e4ce1d0bbb3faf5e2959904709afaeddb2683d74/metadata.json
+++ b/c7bcbd447683a01536c22ee1e4ce1d0bbb3faf5e2959904709afaeddb2683d74/metadata.json
@@ -128,5 +128,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3577053/v1/d2b4bff7c488930c475f7ca8.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c7fb7bec865f8bf282854fafba3e4ff2766baddfefba6015a0c7d97dc53bd5f5/metadata.json b/c7fb7bec865f8bf282854fafba3e4ff2766baddfefba6015a0c7d97dc53bd5f5/metadata.json
index 5196bb57da334c060840f00e373d2f9f125a68ca..7119c948017573402145f653e49714c57caa0ef2 100644
--- a/c7fb7bec865f8bf282854fafba3e4ff2766baddfefba6015a0c7d97dc53bd5f5/metadata.json
+++ b/c7fb7bec865f8bf282854fafba3e4ff2766baddfefba6015a0c7d97dc53bd5f5/metadata.json
@@ -173,5 +173,19 @@
             "section_text": "Nature Reviews Neuroscience (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementarytable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2347992/v1/80ebff1c7532366ee8fbe6bc.xlsx"
+        },
+        {
+            "title": "Supplementarytable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2347992/v1/75989fd529614d35951b2c23.xlsx"
+        },
+        {
+            "title": "Supplementarytable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2347992/v1/b896bb16c25f08297ea05f00.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c83657734c19d732b84601916db41e87d85c2919460a497327b0b09ca11648ab/metadata.json b/c83657734c19d732b84601916db41e87d85c2919460a497327b0b09ca11648ab/metadata.json
index 73a692b365a698d26946ba916667bcf648520b1f..2e32fadda91162ade91e440bdfdb9291ee3cfd8c 100644
--- a/c83657734c19d732b84601916db41e87d85c2919460a497327b0b09ca11648ab/metadata.json
+++ b/c83657734c19d732b84601916db41e87d85c2919460a497327b0b09ca11648ab/metadata.json
@@ -143,5 +143,11 @@
             "section_text": "npj Computational Materials (2025)\n\nRare Metals (2025)\n\nIonics (2025)\n\nScientific Reports (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "UniMOFSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2923144/v1/1c1d06dfc2273b7bd15e40a4.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c8ea0fd9793775451b1580cefcf4cd08c8dfd9b2baff1b29377d0ff48c5d5b10/metadata.json b/c8ea0fd9793775451b1580cefcf4cd08c8dfd9b2baff1b29377d0ff48c5d5b10/metadata.json
index 2e7ab1fa54bc816b3c3af2e289f8402d2b8ef6e7..82e0e82014201744c5c056b1c3196156c1d78eb9 100644
--- a/c8ea0fd9793775451b1580cefcf4cd08c8dfd9b2baff1b29377d0ff48c5d5b10/metadata.json
+++ b/c8ea0fd9793775451b1580cefcf4cd08c8dfd9b2baff1b29377d0ff48c5d5b10/metadata.json
@@ -158,5 +158,11 @@
             "section_text": "Collection\n\nFocus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MASIHirabayashi.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3598104/v1/e60ebd2de0b9735517d805c7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/c97fae2081b3c70a4db079c3b13b5d4001b9db983346912d2d2d2d08573f4a53/metadata.json b/c97fae2081b3c70a4db079c3b13b5d4001b9db983346912d2d2d2d08573f4a53/metadata.json
index 01b4e19b7b977b8ed3d16d3f22a4785a871ab2a2..02da388bcc21e7f62983e8f67414c6d7b6fe9183 100644
--- a/c97fae2081b3c70a4db079c3b13b5d4001b9db983346912d2d2d2d08573f4a53/metadata.json
+++ b/c97fae2081b3c70a4db079c3b13b5d4001b9db983346912d2d2d2d08573f4a53/metadata.json
@@ -200,5 +200,27 @@
             "section_text": "Chinese Medicine (2025)\n\nJournal of Translational Medicine (2025)\n\nScientific Data (2025)\n\nArchives of Orthopaedic and Trauma Surgery (2025)\n\nSignal Transduction and Targeted Therapy (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementarydatafile1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3166544/v1/e6aef49f8dd262d46e22e8f1.xlsx"
+        },
+        {
+            "title": "Supplementarydatafile2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3166544/v1/e7b9863a9fcdf724a9db47f4.xlsx"
+        },
+        {
+            "title": "Supplementarydatafile3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3166544/v1/e2921a5791eb217080a5a2dc.xlsx"
+        },
+        {
+            "title": "Supplementarydatafile4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3166544/v1/776ce30b16b2703c68dd1be0.xlsx"
+        },
+        {
+            "title": "SupplementaryFiguremerged.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3166544/v1/522912d9cd02e2fd9d6d7051.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cafb410808fd614f4506625850818543b8d477e1606359cb89c19b420bdcce69/metadata.json b/cafb410808fd614f4506625850818543b8d477e1606359cb89c19b420bdcce69/metadata.json
index e4dfb27d62cbb82f3236a38e060d9c9ab1ef5980..cb133b85249a380c9609b3ff2411ce492a2366cc 100644
--- a/cafb410808fd614f4506625850818543b8d477e1606359cb89c19b420bdcce69/metadata.json
+++ b/cafb410808fd614f4506625850818543b8d477e1606359cb89c19b420bdcce69/metadata.json
@@ -128,5 +128,11 @@
             "section_text": "Scientific Reports (2025)\n\nNature Photonics (2024)\n\nLight: Science & Applications (2024)\n\nOptical and Quantum Electronics (2024)\n\nOptical and Quantum Electronics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryandAdditionalMaterial.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-954112/v1/2debb535efa9de8e1c2efc4c.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cb959913632e3d3f8b15a53d9ac80a2e1c17267ddd03a244fa8ef00e58d2db3d/metadata.json b/cb959913632e3d3f8b15a53d9ac80a2e1c17267ddd03a244fa8ef00e58d2db3d/metadata.json
index b7ee6be60d12319c300b9abed51595cc9e3e6a1c..1f3c9479df63ef75c6858cb489ba14fcec2a4ab8 100644
--- a/cb959913632e3d3f8b15a53d9ac80a2e1c17267ddd03a244fa8ef00e58d2db3d/metadata.json
+++ b/cb959913632e3d3f8b15a53d9ac80a2e1c17267ddd03a244fa8ef00e58d2db3d/metadata.json
@@ -137,5 +137,19 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "FinalESI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5010739/v1/45d54cdee8d71602f5688967.pdf"
+        },
+        {
+            "title": "checkcif.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5010739/v1/f8f625311e0f7764f1109262.pdf"
+        },
+        {
+            "title": "bigcif.cif",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5010739/v1/f0e659041cde84b7bc92ecbe.cif"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cd52ab7b54bb8497bc0b7f335b9a00991d1796a26492794124444680710fc23d/metadata.json b/cd52ab7b54bb8497bc0b7f335b9a00991d1796a26492794124444680710fc23d/metadata.json
index 8b839f86f64d90ba80d00a97796eed74afae924a..447d7c23e7b54666dea691c4c4dfd891ac1acdd6 100644
--- a/cd52ab7b54bb8497bc0b7f335b9a00991d1796a26492794124444680710fc23d/metadata.json
+++ b/cd52ab7b54bb8497bc0b7f335b9a00991d1796a26492794124444680710fc23d/metadata.json
@@ -179,5 +179,19 @@
             "section_text": "npj Microgravity (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformationNCOMMS2361122A.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4015466/v1/3ffcb261c17df32e040784ab.docx"
+        },
+        {
+            "title": "SourceDataNCOMMS2361122A.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4015466/v1/ef7a132f2762e04a9426ff0c.xlsx"
+        },
+        {
+            "title": "NCOMMS2361122Ars.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4015466/v1/2198358e9e7ecd7c5ac9f8e6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cd5d5f59492da3c7b88a8bc52af56805f2f4b4e24291d14d88ebf7086173b9a2/metadata.json b/cd5d5f59492da3c7b88a8bc52af56805f2f4b4e24291d14d88ebf7086173b9a2/metadata.json
index 57a47c3f0a18e223f2427cb7ac27d89576840bd8..cc21a86d4dfde1f30e72ce587c29927ca9dd4c74 100644
--- a/cd5d5f59492da3c7b88a8bc52af56805f2f4b4e24291d14d88ebf7086173b9a2/metadata.json
+++ b/cd5d5f59492da3c7b88a8bc52af56805f2f4b4e24291d14d88ebf7086173b9a2/metadata.json
@@ -148,5 +148,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-152918/v1/e496457eeab71b476834b311.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cdc3337a4eaac5a07a449066de8adc73931e3ebeb38ef5189b3d64fd4d1418d9/metadata.json b/cdc3337a4eaac5a07a449066de8adc73931e3ebeb38ef5189b3d64fd4d1418d9/metadata.json
index 10b93bedc55103396794a802fc7cc40a15d17d31..f668a94baa0f7455281dbbc7d0cd2c28fd5b75d0 100644
--- a/cdc3337a4eaac5a07a449066de8adc73931e3ebeb38ef5189b3d64fd4d1418d9/metadata.json
+++ b/cdc3337a4eaac5a07a449066de8adc73931e3ebeb38ef5189b3d64fd4d1418d9/metadata.json
@@ -152,5 +152,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Droughtmanuscriptsupplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2841861/v1/3b322772a114cf35f3d3631e.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ce4c419b66d97b411c116d87e96827c63ef16ad385bf6961ac6d54a43ccd1c25/metadata.json b/ce4c419b66d97b411c116d87e96827c63ef16ad385bf6961ac6d54a43ccd1c25/metadata.json
index 35a712e4f389f2f66367813f8bc238ec2464e2bc..0ca161dc89f5c097e46ae233ded1a65a507cfb98 100644
--- a/ce4c419b66d97b411c116d87e96827c63ef16ad385bf6961ac6d54a43ccd1c25/metadata.json
+++ b/ce4c419b66d97b411c116d87e96827c63ef16ad385bf6961ac6d54a43ccd1c25/metadata.json
@@ -157,5 +157,19 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SISDCHomocompositeHydrogelsNatComFinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-110699/v1/4a4a87704f7f21de100ea887.pdf"
+        },
+        {
+            "title": "SupplementaryVideo1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-110699/v1/015a1b8fed2a839934d1dc19.mp4"
+        },
+        {
+            "title": "SupplementaryVideo2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-110699/v1/c66185e42ab6a859c7c3eecd.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/cf861de02bdbfc120a33c2f28d14ba645664976f3691929cf6371212fce98932/metadata.json b/cf861de02bdbfc120a33c2f28d14ba645664976f3691929cf6371212fce98932/metadata.json
index 298b9df9ffe56a1a2ef8cb9b0b92ec5898bad31d..cf65823662c5a1b65e856d58f3b369091e5c7c1e 100644
--- a/cf861de02bdbfc120a33c2f28d14ba645664976f3691929cf6371212fce98932/metadata.json
+++ b/cf861de02bdbfc120a33c2f28d14ba645664976f3691929cf6371212fce98932/metadata.json
@@ -188,5 +188,15 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryvideo.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-219933/v1/30e657c16a33553d8bad795f.zip"
+        },
+        {
+            "title": "supplementary210207submit.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-219933/v1/e6014cb7a3680641417978e7.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d070c2e5ab8199af7c2620038038b8f0e4d45d87fa95e703e189dcf6d4b25c04/metadata.json b/d070c2e5ab8199af7c2620038038b8f0e4d45d87fa95e703e189dcf6d4b25c04/metadata.json
index 5c630fad79527a5671ff7107abefdc37ddad9697..f34aacbaf2dc02ed7b8a310aba3fd23cbd46f3b6 100644
--- a/d070c2e5ab8199af7c2620038038b8f0e4d45d87fa95e703e189dcf6d4b25c04/metadata.json
+++ b/d070c2e5ab8199af7c2620038038b8f0e4d45d87fa95e703e189dcf6d4b25c04/metadata.json
@@ -140,5 +140,19 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SuppTable1ATACSignificantHIVvARTPWHVd1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4784403/v1/ffdcb21689b14792df8d26ac.xlsx"
+        },
+        {
+            "title": "SuppTable2IPDARawdata.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4784403/v1/57ade618ae49d38c95a5af8d.xlsx"
+        },
+        {
+            "title": "SuppTable3QVOA.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4784403/v1/0aa5ce0d328ff5f87a791cb8.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d0d5cdfcde5cfd64d20bfd9c0122fc34559797f06070cbe8ede3e3f160f8d1c4/metadata.json b/d0d5cdfcde5cfd64d20bfd9c0122fc34559797f06070cbe8ede3e3f160f8d1c4/metadata.json
index 2eb8298d7b5feb4b34e9cd361fc00da950567b3e..97ddbf7c679003369482e41055f44ab520b0d88a 100644
--- a/d0d5cdfcde5cfd64d20bfd9c0122fc34559797f06070cbe8ede3e3f160f8d1c4/metadata.json
+++ b/d0d5cdfcde5cfd64d20bfd9c0122fc34559797f06070cbe8ede3e3f160f8d1c4/metadata.json
@@ -137,5 +137,11 @@
             "section_text": "Meccanica (2025)\n\nScientific Reports (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3097054/v1/cb1142b08fc1b60ffcb338e1.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d2f76ea67b786e4acaaaaa5b49c93e0b9b1e0404c5704b2d29b7c0a97bbc911b/metadata.json b/d2f76ea67b786e4acaaaaa5b49c93e0b9b1e0404c5704b2d29b7c0a97bbc911b/metadata.json
index c01e04aef29fcb56d7117f724de32abd6f66a2cd..230e3b801a7091e0365e3bfd760037e3202aacd7 100644
--- a/d2f76ea67b786e4acaaaaa5b49c93e0b9b1e0404c5704b2d29b7c0a97bbc911b/metadata.json
+++ b/d2f76ea67b786e4acaaaaa5b49c93e0b9b1e0404c5704b2d29b7c0a97bbc911b/metadata.json
@@ -167,5 +167,19 @@
             "section_text": "Nature Communications (2025)\n\nnpj Vaccines (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "JMellorsSupplementaryTablesandFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4693445/v1/63e55e0cff35acd2f42b2c7c.pdf"
+        },
+        {
+            "title": "JMellorsSupplementaryTable3.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4693445/v1/79898323cbc42d1c0afa426e.xlsx"
+        },
+        {
+            "title": "JMellorsSupplementaryTable4.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4693445/v1/d8d6bf0fcfc9fe1e081d18a7.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d31934a4fb63bd8a937b8cb7145e4cc3bd67bf751d65b0ea55bd5f1a62e02bd9/metadata.json b/d31934a4fb63bd8a937b8cb7145e4cc3bd67bf751d65b0ea55bd5f1a62e02bd9/metadata.json
index fcf2e4a54a2f3f98fa3597f5995f7cc9ee7031a6..aa53f50649a9d7064e5f6f3cfcb1413c58c5a47e 100644
--- a/d31934a4fb63bd8a937b8cb7145e4cc3bd67bf751d65b0ea55bd5f1a62e02bd9/metadata.json
+++ b/d31934a4fb63bd8a937b8cb7145e4cc3bd67bf751d65b0ea55bd5f1a62e02bd9/metadata.json
@@ -165,5 +165,19 @@
             "section_text": "Focus",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "D1292148080valreportfullP1pretreatment.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6770178/v1/54d3ae2cea8c652d81e74068.pdf"
+        },
+        {
+            "title": "D1292148074valreportfullP1posttreatment.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6770178/v1/9d225792e1803a125a6dbab3.pdf"
+        },
+        {
+            "title": "SupplementaryAB40fanle138b.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6770178/v1/5073195274df374f3d4ddefb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d3f9e972532e5b9ff738f54d8bdf3ced3446f0901dee7002ff24224e0774df3d/metadata.json b/d3f9e972532e5b9ff738f54d8bdf3ced3446f0901dee7002ff24224e0774df3d/metadata.json
index f5fc2a13a3e02e82113ac924dc23b0639e231c30..077b90bba2afe51ea1d5f79cb9df92cf6d8bb737 100644
--- a/d3f9e972532e5b9ff738f54d8bdf3ced3446f0901dee7002ff24224e0774df3d/metadata.json
+++ b/d3f9e972532e5b9ff738f54d8bdf3ced3446f0901dee7002ff24224e0774df3d/metadata.json
@@ -141,5 +141,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "DataFairNationalCarbonAccountabilityforpastandfutureemissions21November2023.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3655927/v1/4ea780d849e5f1d9da66ece2.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d42277f0db9bdf68799b63611bb87a7bd94efaeeb5841f8503a4446e46be37b2/metadata.json b/d42277f0db9bdf68799b63611bb87a7bd94efaeeb5841f8503a4446e46be37b2/metadata.json
index 04b19fdf5d0357f019b9e7cbfb0ed7c3f0e84c39..0cd91ddf8e977a7e127f7422ecdb675af44f4219 100644
--- a/d42277f0db9bdf68799b63611bb87a7bd94efaeeb5841f8503a4446e46be37b2/metadata.json
+++ b/d42277f0db9bdf68799b63611bb87a7bd94efaeeb5841f8503a4446e46be37b2/metadata.json
@@ -149,5 +149,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supportinginformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5235975/v1/d04f1a6e75b7fc9a6aa53ddc.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d425f9b0b0a38adf596e19644840c54cc090ca7768fad8d81252f1f109e02361/metadata.json b/d425f9b0b0a38adf596e19644840c54cc090ca7768fad8d81252f1f109e02361/metadata.json
index 258615c8e8538e81b52246953e7cfc42be0bddff..dbc40ae37dd07a218c71d7215b43eb7fb4be5332 100644
--- a/d425f9b0b0a38adf596e19644840c54cc090ca7768fad8d81252f1f109e02361/metadata.json
+++ b/d425f9b0b0a38adf596e19644840c54cc090ca7768fad8d81252f1f109e02361/metadata.json
@@ -160,5 +160,11 @@
             "section_text": "BMC Infectious Diseases (2025)\n\nDiscover Public Health (2025)\n\nScientific Reports (2025)\n\nBMC Public Health (2024)\n\nJournal of Epidemiology and Global Health (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Appendix1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-411135/v1/2323e7c43669c78570787dbe.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d62429608af455dfb3898d1ec1dbf35ffe750b30c81658917f22585b63bf7d8a/metadata.json b/d62429608af455dfb3898d1ec1dbf35ffe750b30c81658917f22585b63bf7d8a/metadata.json
index 230d7c220c9c7e1f6f76dc4fa95f9ff2972a0dfc..87c881a71e1ccb5fe5e78b498985456b8d1e760c 100644
--- a/d62429608af455dfb3898d1ec1dbf35ffe750b30c81658917f22585b63bf7d8a/metadata.json
+++ b/d62429608af455dfb3898d1ec1dbf35ffe750b30c81658917f22585b63bf7d8a/metadata.json
@@ -141,5 +141,11 @@
             "section_text": "Nature (2025)\n\nScience China Materials (2025)\n\nJournal of Materials Science: Materials in Electronics (2025)\n\nRare Metals (2025)\n\nJournal of Electronic Materials (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInfor.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-952130/v1/0a7f2ba15f4d2135dd489072.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d632a7173d2acad65ad15f0c25ed840e543186c806052efca27d2b9a9a06896a/metadata.json b/d632a7173d2acad65ad15f0c25ed840e543186c806052efca27d2b9a9a06896a/metadata.json
index 9ba5d03c0cdfa33823eb0f44c0dbbfbf50abd8e7..3bba7bf1446d1bb4ebb29d4f2f56c04d5a1e608d 100644
--- a/d632a7173d2acad65ad15f0c25ed840e543186c806052efca27d2b9a9a06896a/metadata.json
+++ b/d632a7173d2acad65ad15f0c25ed840e543186c806052efca27d2b9a9a06896a/metadata.json
@@ -160,5 +160,15 @@
             "section_text": "BMC Biology (2025)\n\nJournal of Intelligent Manufacturing (2025)\n\nMetallography, Microstructure, and Analysis (2025)\n\nJournal of Materials Engineering and Performance (2025)\n\nThe Journal of Supercomputing (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "GradCAMresults.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-371580/v1/edeb6e20b2622c954e6c2e85.zip"
+        },
+        {
+            "title": "Supplemental.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-371580/v1/cbf3f924522e50a146226cff.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d649553e7f6be7c0fad5d39bb424cf0d8ef3adf0bfcb54de94eb50d96c985f42/metadata.json b/d649553e7f6be7c0fad5d39bb424cf0d8ef3adf0bfcb54de94eb50d96c985f42/metadata.json
index b899f94c553af618662820a8cb5d0e2dc8a35640..948d312c6fe84b7d0e01d14df2bfbaef6058bf93 100644
--- a/d649553e7f6be7c0fad5d39bb424cf0d8ef3adf0bfcb54de94eb50d96c985f42/metadata.json
+++ b/d649553e7f6be7c0fad5d39bb424cf0d8ef3adf0bfcb54de94eb50d96c985f42/metadata.json
@@ -229,5 +229,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "DataS1MerbecovirusSAlignment.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-6097445/v1/9af4e062242f8d8a36c72b34.txt"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d6bdb4a3d6ee8311b69bc2f50f1a3ffe54a2a7bb9036eb60f2d6f70b8faff626/metadata.json b/d6bdb4a3d6ee8311b69bc2f50f1a3ffe54a2a7bb9036eb60f2d6f70b8faff626/metadata.json
index f58f87f8d261ba97393a3b36e99df85b354d6043..5e7149ad8a6c2c1655e6c6ccd82783565911a6d9 100644
--- a/d6bdb4a3d6ee8311b69bc2f50f1a3ffe54a2a7bb9036eb60f2d6f70b8faff626/metadata.json
+++ b/d6bdb4a3d6ee8311b69bc2f50f1a3ffe54a2a7bb9036eb60f2d6f70b8faff626/metadata.json
@@ -128,5 +128,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementarymaterials.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4677647/v1/2fc1b5730b7ff119c3dbd8ed.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d71fd36770c5d63442bd518c5d3e45031b33e8617cb1d616b4a8005bd8b6dbe1/metadata.json b/d71fd36770c5d63442bd518c5d3e45031b33e8617cb1d616b4a8005bd8b6dbe1/metadata.json
index 47aa85e551c41276791bada6b3aabcd5b2e4202e..2699eba91b144cbdce1172fb6476c4433c14b7f8 100644
--- a/d71fd36770c5d63442bd518c5d3e45031b33e8617cb1d616b4a8005bd8b6dbe1/metadata.json
+++ b/d71fd36770c5d63442bd518c5d3e45031b33e8617cb1d616b4a8005bd8b6dbe1/metadata.json
@@ -160,5 +160,15 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTables.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3092600/v1/5c3ffa7bf00093b52250f6ae.pdf"
+        },
+        {
+            "title": "SupplementaryInformation.zip",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3092600/v1/34b8a8fc2e01958bba2845ef.zip"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d7b573c6d87c65a4fb1b8dbf8bbe29ea959ac937bcd4b8bb39e9689674d8dbb3/metadata.json b/d7b573c6d87c65a4fb1b8dbf8bbe29ea959ac937bcd4b8bb39e9689674d8dbb3/metadata.json
index 89e9dbefe81306860ce1813c96a709bdab8b2b43..ad24b28257180efd0e61bdb8ffa75045c53fde4f 100644
--- a/d7b573c6d87c65a4fb1b8dbf8bbe29ea959ac937bcd4b8bb39e9689674d8dbb3/metadata.json
+++ b/d7b573c6d87c65a4fb1b8dbf8bbe29ea959ac937bcd4b8bb39e9689674d8dbb3/metadata.json
@@ -133,5 +133,11 @@
             "section_text": "Nature Reviews Electrical Engineering (2025)\n\nLight: Science & Applications (2025)\n\nnpj Computational Materials (2025)\n\nLight: Science & Applications (2025)\n\nNature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementaryinformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-256140/v1/338ffe0848cca6a04c7c5524.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/d814cb70b0005b18b095ae2b1c060b601af866e50eacd7b2d7abe798c6366e20/metadata.json b/d814cb70b0005b18b095ae2b1c060b601af866e50eacd7b2d7abe798c6366e20/metadata.json
index 8ebb7f32f08d3fb468443a714fe22545ec161a46..e4bec26837f20d302af225cc6c50894e8318c17c 100644
--- a/d814cb70b0005b18b095ae2b1c060b601af866e50eacd7b2d7abe798c6366e20/metadata.json
+++ b/d814cb70b0005b18b095ae2b1c060b601af866e50eacd7b2d7abe798c6366e20/metadata.json
@@ -174,5 +174,39 @@
             "section_text": "Microsystems & Nanoengineering (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/32aeffb9a19ce91a84e8b5f8.pdf"
+        },
+        {
+            "title": "ListofSupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/510b4f24fbb33b0d30fdcf44.docx"
+        },
+        {
+            "title": "Video1cellpointukiss.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/0e51f26d9eb2d2c12d68eccd.mov"
+        },
+        {
+            "title": "Video2aCellregionukiss.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/6d77871279c846d09456eb97.mov"
+        },
+        {
+            "title": "Video2bCellregionukisslinecuts.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/7caa6709f701d64c58f6515a.mov"
+        },
+        {
+            "title": "Video3ukissTf.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/634d2ccc95eaee46d2954cf4.mov"
+        },
+        {
+            "title": "Video4Demecolcineukiss.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/58a6c4453d3ad8727b80a3ce.mov"
+        },
+        {
+            "title": "Video5Latrunculinukiss.mov",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3054679/v1/670f2edb7707278a95e050fc.mov"
+        }
     ]
 }
\ No newline at end of file
diff --git a/da05199fdc75a75bf0a5031bd67977bc7b3ccf30317e35e5387eabadaf2c9b83/metadata.json b/da05199fdc75a75bf0a5031bd67977bc7b3ccf30317e35e5387eabadaf2c9b83/metadata.json
index d538dddc65a8f1b1bca0fcc4395bae3fb0b0609e..e75860592d933288ff0f70f14d9efe162a635b6b 100644
--- a/da05199fdc75a75bf0a5031bd67977bc7b3ccf30317e35e5387eabadaf2c9b83/metadata.json
+++ b/da05199fdc75a75bf0a5031bd67977bc7b3ccf30317e35e5387eabadaf2c9b83/metadata.json
@@ -165,5 +165,11 @@
             "section_text": "Nature Communications (2025)\n\nCell Communication and Signaling (2024)\n\nNature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NCSupplementarydataNEW.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-793134/v1/7d672b167073674239acbbae.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/dae07646a5653348365873e4a58bb3182c9ff29d330772dcd4dec7b5d7d9320c/metadata.json b/dae07646a5653348365873e4a58bb3182c9ff29d330772dcd4dec7b5d7d9320c/metadata.json
index 44ad535e271244f3dda94baad1418bf1aa05f633..5ad1669436343d064f277eda536c803ee229b9c5 100644
--- a/dae07646a5653348365873e4a58bb3182c9ff29d330772dcd4dec7b5d7d9320c/metadata.json
+++ b/dae07646a5653348365873e4a58bb3182c9ff29d330772dcd4dec7b5d7d9320c/metadata.json
@@ -142,5 +142,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIFusedMultimodalTomography.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2777794/v1/b4d52b27164c344f8385f8fb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/dae294b352f20f09dac50509466421c7c5c95b7af41869c3e15552b9836be7e6/metadata.json b/dae294b352f20f09dac50509466421c7c5c95b7af41869c3e15552b9836be7e6/metadata.json
index f179a5af49eba0326a8f67e81b771771dcb970a3..d41407ef1018ddce1cee07f2224b9cb9920fd798 100644
--- a/dae294b352f20f09dac50509466421c7c5c95b7af41869c3e15552b9836be7e6/metadata.json
+++ b/dae294b352f20f09dac50509466421c7c5c95b7af41869c3e15552b9836be7e6/metadata.json
@@ -159,5 +159,11 @@
             "section_text": "PhotoniX (2025)\n\nNature Communications (2025)\n\nScience China Technological Sciences (2025)\n\nLight: Science & Applications (2024)\n\nScientific Reports (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SOSLIsupplementarymaterialV6.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-104907/v1/0983719729d61fe83cc3431c.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/db870608704bd352aca3c30f32878fdf646e70076b91accf57729f03275f4ee6/metadata.json b/db870608704bd352aca3c30f32878fdf646e70076b91accf57729f03275f4ee6/metadata.json
index 7f78f23e48f5b657655046b9c68547df5df66195..e2a5316f8ecb6388feff86cac05216d578c151d9 100644
--- a/db870608704bd352aca3c30f32878fdf646e70076b91accf57729f03275f4ee6/metadata.json
+++ b/db870608704bd352aca3c30f32878fdf646e70076b91accf57729f03275f4ee6/metadata.json
@@ -151,5 +151,11 @@
             "section_text": "Surveys in Geophysics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PolaritytransitionofcoronaactivitySupplementaryinformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3389058/v1/2aa4d6beeded0f24d721b406.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/db8ffa8dfe9d5d2f7eabc2994389482dd18694a824ed33aad8f57e44996bd6ec/metadata.json b/db8ffa8dfe9d5d2f7eabc2994389482dd18694a824ed33aad8f57e44996bd6ec/metadata.json
index 61f8044d1e6bd988823d5f9049ad1bf933562b84..7496098a1921d8d4e4b4ffeeebd536a497d7677d 100644
--- a/db8ffa8dfe9d5d2f7eabc2994389482dd18694a824ed33aad8f57e44996bd6ec/metadata.json
+++ b/db8ffa8dfe9d5d2f7eabc2994389482dd18694a824ed33aad8f57e44996bd6ec/metadata.json
@@ -141,5 +141,11 @@
             "section_text": "Nature Sustainability (2025)\n\nCommunications Earth & Environment (2025)\n\nNature Communications (2025)\n\nKorean Journal of Chemical Engineering (2025)\n\nEnvironmental Science and Pollution Research (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupmaterialFirstsubmissionNEEuropeanhydrogen.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3185467/v1/59b5f76a99539834db423c4e.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/dba14940ed3163f74298434a679d33cecd12cfadccda79a29442060e0c214985/metadata.json b/dba14940ed3163f74298434a679d33cecd12cfadccda79a29442060e0c214985/metadata.json
index 4be2ffb7cd3d1679c74784e024738c695b2d3609..07557aebfa47cc7a7b8587f4895f4570e5672734 100644
--- a/dba14940ed3163f74298434a679d33cecd12cfadccda79a29442060e0c214985/metadata.json
+++ b/dba14940ed3163f74298434a679d33cecd12cfadccda79a29442060e0c214985/metadata.json
@@ -140,5 +140,11 @@
             "section_text": "Journal of Electronic Materials (2025)\n\nNature Communications (2024)\n\nnpj Quantum Materials (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MethodsXExtendeddata.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-929834/v1/5e6e2d1cb7d67cadb97c8ce6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/dc82b16faa4d98cd21bb017c49f8f01aa89b418aa69ecc3aa7a87adc3e1de3f4/metadata.json b/dc82b16faa4d98cd21bb017c49f8f01aa89b418aa69ecc3aa7a87adc3e1de3f4/metadata.json
index a9b9ae2fd524bb011bd80940bf70bd6bd561f530..16404e8b5202ffb7e28bf76eed72eaaf982872b9 100644
--- a/dc82b16faa4d98cd21bb017c49f8f01aa89b418aa69ecc3aa7a87adc3e1de3f4/metadata.json
+++ b/dc82b16faa4d98cd21bb017c49f8f01aa89b418aa69ecc3aa7a87adc3e1de3f4/metadata.json
@@ -154,5 +154,23 @@
             "section_text": "BMC Neurology (2025)\n\nNature Cell Biology (2025)\n\nSignal Transduction and Targeted Therapy (2025)\n\nNature Reviews Cancer (2025)\n\nMolecular Cancer (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2039668/v1/d2725c7a95b2960c3652cf2e.xlsx"
+        },
+        {
+            "title": "SupplementaryTable2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2039668/v1/d7bc393123d7005c83780deb.xlsx"
+        },
+        {
+            "title": "ExtendedDataFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2039668/v1/10f824efc0c42b45f188aa94.pdf"
+        },
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2039668/v1/dd5b7908197645ec4954394f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/dd9c67fea4a3292bcbe0c5f14d2002b72dcb4e8802a0ee1f672dd16ca4e4336a/metadata.json b/dd9c67fea4a3292bcbe0c5f14d2002b72dcb4e8802a0ee1f672dd16ca4e4336a/metadata.json
index 5cb8025353951b03795fb51d956a8716dd3ef3eb..3585f81b643b8331266a5bc3ae34fba2e034c606 100644
--- a/dd9c67fea4a3292bcbe0c5f14d2002b72dcb4e8802a0ee1f672dd16ca4e4336a/metadata.json
+++ b/dd9c67fea4a3292bcbe0c5f14d2002b72dcb4e8802a0ee1f672dd16ca4e4336a/metadata.json
@@ -159,5 +159,11 @@
             "section_text": "Communications Biology (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "PRStuningSupplementaryNotes.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2939390/v1/71f76152b717f8ce56b1f4c1.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/deffadbb7826afdf2ab8ad33c642df1e1e47832002716b5ccbc5b5c2417b4676/metadata.json b/deffadbb7826afdf2ab8ad33c642df1e1e47832002716b5ccbc5b5c2417b4676/metadata.json
index 9cd6dfc353166fc8067efada0fc508c5580165c4..71e270cfe08da13cc9f1ac3dd5df59a781bcf068 100644
--- a/deffadbb7826afdf2ab8ad33c642df1e1e47832002716b5ccbc5b5c2417b4676/metadata.json
+++ b/deffadbb7826afdf2ab8ad33c642df1e1e47832002716b5ccbc5b5c2417b4676/metadata.json
@@ -160,5 +160,15 @@
             "section_text": "BMC Plant Biology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "AsparagalesSupplementarytables20240422.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4312784/v1/0b714494c7b27e83814c5e64.xlsx"
+        },
+        {
+            "title": "Asparagalessupplementarytextandfigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4312784/v1/21e259a5104c56e200227cdb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/df8d6d6325e463d976feb5f3c2a491e81edbbc83f1a51129123d40ceade37bf1/metadata.json b/df8d6d6325e463d976feb5f3c2a491e81edbbc83f1a51129123d40ceade37bf1/metadata.json
index b3e9fd505af6d9c261fabdbd85b2a81908b133dd..2ae45a3cfb5d7f042e1da4056578c7f48dd619b5 100644
--- a/df8d6d6325e463d976feb5f3c2a491e81edbbc83f1a51129123d40ceade37bf1/metadata.json
+++ b/df8d6d6325e463d976feb5f3c2a491e81edbbc83f1a51129123d40ceade37bf1/metadata.json
@@ -147,5 +147,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "AppendixFigures20240613.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4579270/v1/61f3c409cdfa0101c747510e.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e073a2e9ce91b73a0f853e6a671c559f3651dc4805dbdbd1bfdde7aef3359a68/metadata.json b/e073a2e9ce91b73a0f853e6a671c559f3651dc4805dbdbd1bfdde7aef3359a68/metadata.json
index fe9070b0c3895a4a0a5f8746ec5bd81854c4e8ef..8c14bb402e97679607c76e868afa87a106624439 100644
--- a/e073a2e9ce91b73a0f853e6a671c559f3651dc4805dbdbd1bfdde7aef3359a68/metadata.json
+++ b/e073a2e9ce91b73a0f853e6a671c559f3651dc4805dbdbd1bfdde7aef3359a68/metadata.json
@@ -132,5 +132,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "ESRFfryingNatCommSupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4578278/v1/eaf436de5f2857075c5e5958.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e0d109173b568ed601260c6c3130ebb47ab5ff6d0854cd0d4da5bcc84d24795e/metadata.json b/e0d109173b568ed601260c6c3130ebb47ab5ff6d0854cd0d4da5bcc84d24795e/metadata.json
index 83a1f91f7971cb9da6ad64bb7039b2da4cc96ce2..5d0ebf9dcd3323547811b7d10fef7f49ad8ae4ae 100644
--- a/e0d109173b568ed601260c6c3130ebb47ab5ff6d0854cd0d4da5bcc84d24795e/metadata.json
+++ b/e0d109173b568ed601260c6c3130ebb47ab5ff6d0854cd0d4da5bcc84d24795e/metadata.json
@@ -148,5 +148,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "supplementaryfigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3759654/v1/d6e1087879895a4fb7f0c6a0.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e0e48631b97283a211409cd4aa3a79cf17c9ba763b598e2816907d2ad0477be9/metadata.json b/e0e48631b97283a211409cd4aa3a79cf17c9ba763b598e2816907d2ad0477be9/metadata.json
index 156bc051505df67888f77751f71e72bdbbbde595..6fe2c048deb95df7fef531216a75b2927c64a796 100644
--- a/e0e48631b97283a211409cd4aa3a79cf17c9ba763b598e2816907d2ad0477be9/metadata.json
+++ b/e0e48631b97283a211409cd4aa3a79cf17c9ba763b598e2816907d2ad0477be9/metadata.json
@@ -175,5 +175,35 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SMRhythmcontrol20240621combinedBM.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/b0fac9598bac9d3ce7f9eec5.pdf"
+        },
+        {
+            "title": "VideoS1Vibration16HzDemo60fps.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/ba310f59754ab1346722f2b4.mp4"
+        },
+        {
+            "title": "VideoS2MouseonVibration30fpsHEVC.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/de558e28b235edd13414d132.mp4"
+        },
+        {
+            "title": "VideoS3VibrationDemoChirp60fps.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/d5ad5fbdfc38e43a67c068c6.mp4"
+        },
+        {
+            "title": "VideoS4ChirpOpto2vN3.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/284aa45f19aadd6a5fdd97e8.mp4"
+        },
+        {
+            "title": "nBME241901PanDataFileS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/4997cbf0f7d443f7e39948d1.xlsx"
+        },
+        {
+            "title": "nBME241901PanDataFileS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4615547/v1/ce0cdc9531f2d81099761a3a.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e732ec489eb8b652f7f877ef68931801f077db32e6b3f13c35f6cc25dd441c49/metadata.json b/e732ec489eb8b652f7f877ef68931801f077db32e6b3f13c35f6cc25dd441c49/metadata.json
index dde3e6b7ca61c13a245fdb3caaa7fa24f176a2d0..691057b553d435b3e4d9c75070173a8a67decc7e 100644
--- a/e732ec489eb8b652f7f877ef68931801f077db32e6b3f13c35f6cc25dd441c49/metadata.json
+++ b/e732ec489eb8b652f7f877ef68931801f077db32e6b3f13c35f6cc25dd441c49/metadata.json
@@ -175,5 +175,27 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "BERTPhylosupplementaryinfo.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4611601/v1/844a6a93b074e36f6b304142.pdf"
+        },
+        {
+            "title": "BERTPhylosupplementarydataset.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4611601/v1/78c1bfed75dfafe59793c96f.xlsx"
+        },
+        {
+            "title": "BERTPhylosupplementarysourcedata.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4611601/v1/98901c4d540d6a23c4fe411a.xlsx"
+        },
+        {
+            "title": "sp2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4611601/v1/07203ac18ca59fe32c57d2be.pdf"
+        },
+        {
+            "title": "rs1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4611601/v1/03d47def285412c80e397348.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e7c62c51a1fbbd4604d7c4b0b820822cf6221f74fa07d47f3253bbd8c4aff57b/metadata.json b/e7c62c51a1fbbd4604d7c4b0b820822cf6221f74fa07d47f3253bbd8c4aff57b/metadata.json
index d2bbd0b6a5ce455c3a7a3141953d48c498605a37..cfc2f2083e4f4b458e9cae559202dc3f51c027b6 100644
--- a/e7c62c51a1fbbd4604d7c4b0b820822cf6221f74fa07d47f3253bbd8c4aff57b/metadata.json
+++ b/e7c62c51a1fbbd4604d7c4b0b820822cf6221f74fa07d47f3253bbd8c4aff57b/metadata.json
@@ -168,5 +168,11 @@
             "section_text": "Acta Pharmacologica Sinica (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "320231129SuppFiguresNiche.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3683532/v1/3c0207f3cce7171657159fc8.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/e7fc45b897a9c880c15312761bbc0e1255a0612747eb7ba13cec357c1c64d6ff/metadata.json b/e7fc45b897a9c880c15312761bbc0e1255a0612747eb7ba13cec357c1c64d6ff/metadata.json
index 74e6f7c3a1f8a0f6a0a8fbae6848ebfeffb54b77..7c2ad1b3652c099933e780c8182a6d6be96958c2 100644
--- a/e7fc45b897a9c880c15312761bbc0e1255a0612747eb7ba13cec357c1c64d6ff/metadata.json
+++ b/e7fc45b897a9c880c15312761bbc0e1255a0612747eb7ba13cec357c1c64d6ff/metadata.json
@@ -128,5 +128,15 @@
             "section_text": "Communications Earth & Environment (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "14CO2PanamashortformatMethods090723.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3409233/v1/21f2d601ca254e8d73330483.pdf"
+        },
+        {
+            "title": "14CO2PanamashortformatSupplement090723.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3409233/v1/2d9ece9ca0e16bf062ba9e11.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/eb9325fd667fb4c0c5b00f1e354eafc7910a5255800f4fdfb76b6d8cb95650bc/metadata.json b/eb9325fd667fb4c0c5b00f1e354eafc7910a5255800f4fdfb76b6d8cb95650bc/metadata.json
index 07bd6096d7fae4852d0fc168aa46b01ab386306d..772db819058623152d04959ac7804dd7a2541043 100644
--- a/eb9325fd667fb4c0c5b00f1e354eafc7910a5255800f4fdfb76b6d8cb95650bc/metadata.json
+++ b/eb9325fd667fb4c0c5b00f1e354eafc7910a5255800f4fdfb76b6d8cb95650bc/metadata.json
@@ -142,5 +142,11 @@
             "section_text": "Science China Chemistry (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3749314/v1/525705d34f9aba672ec282f6.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ee9cc53224ccafab21d680b33c3ae4d99689de3b8c1b73782c151902b830f4be/metadata.json b/ee9cc53224ccafab21d680b33c3ae4d99689de3b8c1b73782c151902b830f4be/metadata.json
index 07ec0b842016649e8b1aa44e53f8d6179ba408cb..a54d96d6495588ba8c16d18a9b2e77c493824b14 100644
--- a/ee9cc53224ccafab21d680b33c3ae4d99689de3b8c1b73782c151902b830f4be/metadata.json
+++ b/ee9cc53224ccafab21d680b33c3ae4d99689de3b8c1b73782c151902b830f4be/metadata.json
@@ -120,5 +120,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3345186/v1/e944832729e467a5a86a4330.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ef0e80533c18ae3a7964503c340b3dd13939d3ba3307dfa316d1edd1b15ea344/metadata.json b/ef0e80533c18ae3a7964503c340b3dd13939d3ba3307dfa316d1edd1b15ea344/metadata.json
index 2ff9ee82b764a077db931bfb7e176e6c2424fb05..e91ff720089e7f73baf014eab393791d547a618c 100644
--- a/ef0e80533c18ae3a7964503c340b3dd13939d3ba3307dfa316d1edd1b15ea344/metadata.json
+++ b/ef0e80533c18ae3a7964503c340b3dd13939d3ba3307dfa316d1edd1b15ea344/metadata.json
@@ -188,5 +188,23 @@
             "section_text": "Scientific Reports (2025)\n\nClinical and Experimental Medicine (2025)\n\nMolecular Diversity (2025)\n\nJournal of Cardiovascular Translational Research (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "RondeauxMSsupplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-263770/v1/bd3f7f867488ce04c225920a.pdf"
+        },
+        {
+            "title": "Supplementarytable1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-263770/v1/ede66e159000784e5036f5f5.xlsx"
+        },
+        {
+            "title": "Supplementarytable2.xls",
+            "link": "https://assets-eu.researchsquare.com/files/rs-263770/v1/061c2d3ac74c8ba387a7df3d.xls"
+        },
+        {
+            "title": "Supplementarytable3.xls",
+            "link": "https://assets-eu.researchsquare.com/files/rs-263770/v1/995b45c2b47885b51a223d57.xls"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f028c380cf45f69d8918d5d5cc082aeef1b9815986ab85da59857eb6431b87e9/metadata.json b/f028c380cf45f69d8918d5d5cc082aeef1b9815986ab85da59857eb6431b87e9/metadata.json
index 24ead63acaf136b732fbcc85c6d8043c427166c4..3ada59ab4db302381b13d01f8d3ab286c6536720 100644
--- a/f028c380cf45f69d8918d5d5cc082aeef1b9815986ab85da59857eb6431b87e9/metadata.json
+++ b/f028c380cf45f69d8918d5d5cc082aeef1b9815986ab85da59857eb6431b87e9/metadata.json
@@ -129,5 +129,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2382225/v1/97545248785171bd093aad15.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f0aa6563a2e2c1778542a9ccef84fa18db2e04319699022f3d83c3646751a3b0/metadata.json b/f0aa6563a2e2c1778542a9ccef84fa18db2e04319699022f3d83c3646751a3b0/metadata.json
index 0ceb24086eadd4764735b3d0de650a164fe4d221..a9d787569cf2c310ff0303c414bdee806e6a76a4 100644
--- a/f0aa6563a2e2c1778542a9ccef84fa18db2e04319699022f3d83c3646751a3b0/metadata.json
+++ b/f0aa6563a2e2c1778542a9ccef84fa18db2e04319699022f3d83c3646751a3b0/metadata.json
@@ -141,5 +141,11 @@
             "section_text": "Light: Science & Applications (2025)\n\nPhotonic Sensors (2025)\n\nLight: Science & Applications (2024)\n\nLight: Science & Applications (2024)\n\nLight: Science & Applications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1106913/v1/86df909a5f5fbdd428b0a4c2.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f129fea6e26ea3ac2e288c1dd87f8e1456b5719ae4d6f083e545eaee5fc60cb4/metadata.json b/f129fea6e26ea3ac2e288c1dd87f8e1456b5719ae4d6f083e545eaee5fc60cb4/metadata.json
index a624b40d56a5f453cfa2f100366e5bb305213d31..41dc6823b4ca99645690b1ec675873deea1cf686 100644
--- a/f129fea6e26ea3ac2e288c1dd87f8e1456b5719ae4d6f083e545eaee5fc60cb4/metadata.json
+++ b/f129fea6e26ea3ac2e288c1dd87f8e1456b5719ae4d6f083e545eaee5fc60cb4/metadata.json
@@ -138,5 +138,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "20220602EnergytransferSI.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1691869/v1/fe006f1daf0af5e777c3d3ff.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f1ebcf24f9cd16638ca905ba55b36d64ea9a4d2fcda898fdeadbc42e320e0dd0/metadata.json b/f1ebcf24f9cd16638ca905ba55b36d64ea9a4d2fcda898fdeadbc42e320e0dd0/metadata.json
index 596131693977c8d0e8cd919c10185445d63c3d9d..4f03aa84192c2198cae3518a18dbeff800aaf47b 100644
--- a/f1ebcf24f9cd16638ca905ba55b36d64ea9a4d2fcda898fdeadbc42e320e0dd0/metadata.json
+++ b/f1ebcf24f9cd16638ca905ba55b36d64ea9a4d2fcda898fdeadbc42e320e0dd0/metadata.json
@@ -134,5 +134,11 @@
             "section_text": "Nature Communications (2025)\n\nNature Catalysis (2025)\n\nNature Catalysis (2025)\n\nRare Metals (2025)\n\nIonics (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "CCETSINatCommsubmisson.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1157577/v1/7fcf773bcfd7a39130a6934d.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f2b68f50205bed62a31f98a972fde4f2a0025cdff88fcfc0b8bc175a15746c5b/metadata.json b/f2b68f50205bed62a31f98a972fde4f2a0025cdff88fcfc0b8bc175a15746c5b/metadata.json
index b192fdd19c51844aeb9cd215198ca2f5b70c9482..4eb511fdabe8f5d4d7b75a6be444ccc60f04260d 100644
--- a/f2b68f50205bed62a31f98a972fde4f2a0025cdff88fcfc0b8bc175a15746c5b/metadata.json
+++ b/f2b68f50205bed62a31f98a972fde4f2a0025cdff88fcfc0b8bc175a15746c5b/metadata.json
@@ -134,5 +134,11 @@
             "section_text": "eLight (2025)\n\nAAPPS Bulletin (2025)\n\nLight: Science & Applications (2024)\n\nNano Convergence (2023)\n\nNature Communications (2023)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "fftersnatcommsi.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1175998/v1/72a98e19e7333fb6191c808a.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f3189e8bf15783d57480f1fa6e2df708eb242cb707a800d24d0e923935172baa/metadata.json b/f3189e8bf15783d57480f1fa6e2df708eb242cb707a800d24d0e923935172baa/metadata.json
index df334a355d30c003a70797d04bcb7cda7cedd78c..f50dfc83c2b23b48fec72c649a9ea205e9df6721 100644
--- a/f3189e8bf15783d57480f1fa6e2df708eb242cb707a800d24d0e923935172baa/metadata.json
+++ b/f3189e8bf15783d57480f1fa6e2df708eb242cb707a800d24d0e923935172baa/metadata.json
@@ -233,5 +233,47 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "TableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/280e68d2d6aa4b16453b621e.xlsx"
+        },
+        {
+            "title": "20211113Suppfigurelegends.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/07bc90f66ffc6fe61a293814.docx"
+        },
+        {
+            "title": "20211113suppfigs.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/b807a5f9d01f07dd94f51fe9.pdf"
+        },
+        {
+            "title": "20211113methods.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/3eb1cbfb71bf0afd38aaa7aa.docx"
+        },
+        {
+            "title": "Video1GluGCaMP6fIns2RCaMP3G10G.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/8789b293b3b5887d6f1f88a3.avi"
+        },
+        {
+            "title": "Video2GluGCaMP6fIns2RCaMP1.07fastoscillation.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/792910488a3946515d02a53e.avi"
+        },
+        {
+            "title": "Video3GluGCaMP6fIns2RCaMP1.07slowoscillation.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/43be51e1d500a7588d916212.avi"
+        },
+        {
+            "title": "Video4GluGCaMP6fIns2RCaMP1.07mixoscillation.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/662f8660e0469a58d67d7409.avi"
+        },
+        {
+            "title": "Video5.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/0b73ea17b6f7068ad69cd635.avi"
+        },
+        {
+            "title": "Video6.avi",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1076894/v1/9358dda229e2e5fb59b9535b.avi"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f44300daad7bfde8f42444499b417a03a60fd7630cf33946012de00c4fbbb40e/metadata.json b/f44300daad7bfde8f42444499b417a03a60fd7630cf33946012de00c4fbbb40e/metadata.json
index 7ba6dc7813408ec406ed74ae92639edd6362fcda..1ecbcb2a8ed96d7530a063134a4cc0cb54ad3eea 100644
--- a/f44300daad7bfde8f42444499b417a03a60fd7630cf33946012de00c4fbbb40e/metadata.json
+++ b/f44300daad7bfde8f42444499b417a03a60fd7630cf33946012de00c4fbbb40e/metadata.json
@@ -177,5 +177,15 @@
             "section_text": "Nature Communications (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "MtEfpAlipidspathway.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3740027/v1/625d0ebb3adb658e7854e0a4.mp4"
+        },
+        {
+            "title": "MtEfpAconfomationaltransition.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3740027/v1/c67ff124ad114e49d1b2508b.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f53a29425e17251d3e1c353103a5be9747d0b6704d737f57213ffb516d9e8e00/metadata.json b/f53a29425e17251d3e1c353103a5be9747d0b6704d737f57213ffb516d9e8e00/metadata.json
index 3218635970ae88ef61c6fb5bfe17ddb827eac1be..2337c66f2f88a484ec80f85531eb0d5cfec3c5ee 100644
--- a/f53a29425e17251d3e1c353103a5be9747d0b6704d737f57213ffb516d9e8e00/metadata.json
+++ b/f53a29425e17251d3e1c353103a5be9747d0b6704d737f57213ffb516d9e8e00/metadata.json
@@ -186,5 +186,47 @@
             "section_text": "Nature Reviews Rheumatology (2025)\n\nNature Reviews Nephrology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Table1submit.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/f6428cac0bba1482586f57db.pdf"
+        },
+        {
+            "title": "ExtendedDataFigure1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/da763febd84f52a53812766d.pdf"
+        },
+        {
+            "title": "ExtendedDataFigure2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/304c2ebd62ae29f9360842e9.pdf"
+        },
+        {
+            "title": "OnlineMethodsfinal.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/921fb4623edadd8a5622c2b7.docx"
+        },
+        {
+            "title": "SupplementaryFigure1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/9a9fca7c068714585e5fac6b.pdf"
+        },
+        {
+            "title": "SupplementaryFigure2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/9a27c96a2bbdd5de7cdc53fe.pdf"
+        },
+        {
+            "title": "SupplementaryFigure3.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/ef3fb8fd7ce76c910caa01de.pdf"
+        },
+        {
+            "title": "SupplementaryFigure4.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/2572fa50f8521d835d1f95ae.pdf"
+        },
+        {
+            "title": "SupplementaryFigure5.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/416546438c529c6f8d7f8466.pdf"
+        },
+        {
+            "title": "SupplementaryTable1submit.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3221971/v1/ec7956c1d175470c0d2bdf48.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f5c191fda8d94d18c999baff5f69710d0e9e239ddb0f9b42f2c8a2ebb2d755dd/metadata.json b/f5c191fda8d94d18c999baff5f69710d0e9e239ddb0f9b42f2c8a2ebb2d755dd/metadata.json
index 93b5d0e50f56a91b850dd0f6c508dab1691efb4e..4c090ae55f1f32ad9c33adcbaaac84af2b8cfc62 100644
--- a/f5c191fda8d94d18c999baff5f69710d0e9e239ddb0f9b42f2c8a2ebb2d755dd/metadata.json
+++ b/f5c191fda8d94d18c999baff5f69710d0e9e239ddb0f9b42f2c8a2ebb2d755dd/metadata.json
@@ -180,5 +180,27 @@
             "section_text": "World Journal of Pediatrics (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryData1covidvsnovirusDE.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-784784/v1/2b27154bac44c6e9915f9b4e.xlsx"
+        },
+        {
+            "title": "SupplementaryData2covidvsnovirusfgsea.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-784784/v1/1d003f050aaf06aaa5ae493e.xlsx"
+        },
+        {
+            "title": "SupplementaryData3covidpediatricvsadultDE.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-784784/v1/f2b788947737f038616c3a61.xlsx"
+        },
+        {
+            "title": "SupplementaryData4covidpediatricvsadultfgsea.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-784784/v1/470037b02e281c487a099fb9.xlsx"
+        },
+        {
+            "title": "SupplementaryData5deconvolutionresults.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-784784/v1/66381292fef50e5dfcca3459.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f80a87421c6ec02e708255ef23570eee60bb9ad9f78e6f6154db88ce28c02a21/metadata.json b/f80a87421c6ec02e708255ef23570eee60bb9ad9f78e6f6154db88ce28c02a21/metadata.json
index d9b6b58538ea7f35eb88e82bd6324a5fb11e23fa..420264b37adfca06c4f27fe9851c6d34d55ad0bd 100644
--- a/f80a87421c6ec02e708255ef23570eee60bb9ad9f78e6f6154db88ce28c02a21/metadata.json
+++ b/f80a87421c6ec02e708255ef23570eee60bb9ad9f78e6f6154db88ce28c02a21/metadata.json
@@ -177,5 +177,39 @@
             "section_text": "Scientific Reports (2025)\n\nnpj Biofilms and Microbiomes (2025)\n\nJournal of Plant Diseases and Protection (2025)\n\nnpj Antimicrobials and Resistance (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/689a3dd4326b608d390ee928.pdf"
+        },
+        {
+            "title": "SupplementaryDataset1mutations.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/365052184e7204f1b274c39c.xlsx"
+        },
+        {
+            "title": "SupplementaryDataset2volatiles.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/f21bd19b79c6daddb67f27c8.xlsx"
+        },
+        {
+            "title": "SupplementaryDataset3fungalspeciesidentification.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/4062aab878b12b9059dcfdfe.txt"
+        },
+        {
+            "title": "SupplementaryDataset4figuredata.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/7d74382436dda075ae391ca5.xlsx"
+        },
+        {
+            "title": "SupplementaryTable1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/f232ae3e5e53d16e4ff407e7.pdf"
+        },
+        {
+            "title": "SupplementaryVideo1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/8fbd3ce3b88bc7270e5c7792.mp4"
+        },
+        {
+            "title": "SupplementaryVideo2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3025894/v1/31deabe68254460b71a2659f.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f81356cb54a0579cc28f25e5f4a7e5f3a588c8b5646a45f468e9b1846332f663/metadata.json b/f81356cb54a0579cc28f25e5f4a7e5f3a588c8b5646a45f468e9b1846332f663/metadata.json
index 5a4d5fcdd7b457b27217f97e4bdf4a779f20a03e..e3dedd768a5790324c4230fef277f0e901bb382c 100644
--- a/f81356cb54a0579cc28f25e5f4a7e5f3a588c8b5646a45f468e9b1846332f663/metadata.json
+++ b/f81356cb54a0579cc28f25e5f4a7e5f3a588c8b5646a45f468e9b1846332f663/metadata.json
@@ -175,5 +175,15 @@
             "section_text": "BMC Biology (2025)\n\nJournal of Animal Science and Biotechnology (2025)\n\nBMC Genomics (2025)\n\nBMC Genomics (2025)\n\nJournal of Animal Science and Biotechnology (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "3SupplementaryFig.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-253276/v1/66b596cb780be6644e008c2b.pdf"
+        },
+        {
+            "title": "4SupplementaryTable.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-253276/v1/5a51e88a6dfb91857a74d448.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f875bb69a538f2e5c0d84f6b40d542612153ac456be90ef612a022b30bf9f27f/metadata.json b/f875bb69a538f2e5c0d84f6b40d542612153ac456be90ef612a022b30bf9f27f/metadata.json
index 3429d716e9522f6444e3347a3753bd9674011997..6f9bc99a6b236a090596456e84cefb4ae657aea5 100644
--- a/f875bb69a538f2e5c0d84f6b40d542612153ac456be90ef612a022b30bf9f27f/metadata.json
+++ b/f875bb69a538f2e5c0d84f6b40d542612153ac456be90ef612a022b30bf9f27f/metadata.json
@@ -144,5 +144,11 @@
             "section_text": "Nature Computational Science (2024)\n\nScientific Reports (2023)\n\nCommunications Physics (2022)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-286804/v1/31557b4d3a205053d09740ca.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/f8db1fae210260fd8c6fdf136171f8d54ebd99703698d89d8f0774366bc6d12e/metadata.json b/f8db1fae210260fd8c6fdf136171f8d54ebd99703698d89d8f0774366bc6d12e/metadata.json
index 7e1f0d1308c982d2052419fb56488c7586b5fbc6..682e360244545fa342cc5e0f740dd1e2f4aa9f08 100644
--- a/f8db1fae210260fd8c6fdf136171f8d54ebd99703698d89d8f0774366bc6d12e/metadata.json
+++ b/f8db1fae210260fd8c6fdf136171f8d54ebd99703698d89d8f0774366bc6d12e/metadata.json
@@ -153,5 +153,11 @@
             "section_text": "Collection",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementalmaterialandmethods.doc",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3154268/v1/4cf207244e37a6a910fd1f46.doc"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fa441b1c740d5b06b30d7f07ba0980eff6c87bbbe6d3b6a6a986cafccacc2182/metadata.json b/fa441b1c740d5b06b30d7f07ba0980eff6c87bbbe6d3b6a6a986cafccacc2182/metadata.json
index 15239b2c425250668a64dbd670fabdff2f422155..f99906a94242f79275444a369a354b4bdb8714bc 100644
--- a/fa441b1c740d5b06b30d7f07ba0980eff6c87bbbe6d3b6a6a986cafccacc2182/metadata.json
+++ b/fa441b1c740d5b06b30d7f07ba0980eff6c87bbbe6d3b6a6a986cafccacc2182/metadata.json
@@ -140,5 +140,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "Supplementary.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5247129/v1/43df39f2a93fd24cfd459879.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fa97c78911411833ae9c9646ef157ca420d0f3baef0f717fbe1cd7f94ff3d341/metadata.json b/fa97c78911411833ae9c9646ef157ca420d0f3baef0f717fbe1cd7f94ff3d341/metadata.json
index 7a414a8e0c1185911f5408e59349594085778dda..211129bf56636e043f4dfe73ea32cef60263f504 100644
--- a/fa97c78911411833ae9c9646ef157ca420d0f3baef0f717fbe1cd7f94ff3d341/metadata.json
+++ b/fa97c78911411833ae9c9646ef157ca420d0f3baef0f717fbe1cd7f94ff3d341/metadata.json
@@ -212,5 +212,19 @@
             "section_text": "Evolution: Education and Outreach (2025)\n\nMolecular Psychiatry (2025)\n\nNature Human Behaviour (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SITABLE.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3782300/v1/a83f57e2336ab13bebcd8a3c.xlsx"
+        },
+        {
+            "title": "IncomeGWASSupplementaryInformationText.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3782300/v1/2e5c88846db4f5b86c2b1521.pdf"
+        },
+        {
+            "title": "ExtendedFiguresandSupplementaryFigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3782300/v1/b816e3bbc5178bccbb2f32eb.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/faa6cae15f924cdc013d5c1e4c0628d47190a568950c38e967682f547cd8b79e/metadata.json b/faa6cae15f924cdc013d5c1e4c0628d47190a568950c38e967682f547cd8b79e/metadata.json
index 2f0596e433df94dd1935ab4b8782dc2b9f62a805..7393082e69a448e8c7cfd96e75500408f4a9e54b 100644
--- a/faa6cae15f924cdc013d5c1e4c0628d47190a568950c38e967682f547cd8b79e/metadata.json
+++ b/faa6cae15f924cdc013d5c1e4c0628d47190a568950c38e967682f547cd8b79e/metadata.json
@@ -164,5 +164,19 @@
             "section_text": "Transport in Porous Media (2025)\n\nRare Metals (2025)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SIFinalRef.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3378492/v1/7b3fa3816436c175b6e32d8d.pdf"
+        },
+        {
+            "title": "MovieS1.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3378492/v1/3d26c186fc6f695dfc2b84aa.mp4"
+        },
+        {
+            "title": "MovieS2.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3378492/v1/b884d56dff755c50f8158300.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fb09ef9a6fb02215da4f617c465871a9f69adc2400f74d8995885463b96e7aa6/metadata.json b/fb09ef9a6fb02215da4f617c465871a9f69adc2400f74d8995885463b96e7aa6/metadata.json
index d6462fa553ac7b5c9df43b9f07d9c0e91b14c353..e2e2338e89bfe084a0569aa27b6e4434573d9bc3 100644
--- a/fb09ef9a6fb02215da4f617c465871a9f69adc2400f74d8995885463b96e7aa6/metadata.json
+++ b/fb09ef9a6fb02215da4f617c465871a9f69adc2400f74d8995885463b96e7aa6/metadata.json
@@ -130,5 +130,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "OrigamiTrapezoidsSubmissionSupplement.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5045672/v1/d6ec47ffe1e8adc8501fba9b.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fb8d2a5931d4ec01eafccff056cfe8ac2950a7fd4ab5eaf2ccbe21fb33c756e1/metadata.json b/fb8d2a5931d4ec01eafccff056cfe8ac2950a7fd4ab5eaf2ccbe21fb33c756e1/metadata.json
index 99626833e85dcc850e2b0066a34f18daccdc0ff3..8da0ff7071557bda7cbf7530c8b5cb2bc3ae24ec 100644
--- a/fb8d2a5931d4ec01eafccff056cfe8ac2950a7fd4ab5eaf2ccbe21fb33c756e1/metadata.json
+++ b/fb8d2a5931d4ec01eafccff056cfe8ac2950a7fd4ab5eaf2ccbe21fb33c756e1/metadata.json
@@ -215,5 +215,31 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "NBCHEMOOnlineMethodssept21.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/2b1b09b86e627928004e6323.docx"
+        },
+        {
+            "title": "NBCHEMOSupplDataLegendssept20.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/644ca0f8a9a5b177bc5c24fb.pdf"
+        },
+        {
+            "title": "Suppfigures.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/48ffdc0d5de4c333776d75d5.pdf"
+        },
+        {
+            "title": "TableS1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/5872aa99ca31ca592ec66344.xlsx"
+        },
+        {
+            "title": "TableS2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/81174f0ce66559d50e9599c6.xlsx"
+        },
+        {
+            "title": "NCOMMS2240115TRS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-2104205/v1/75eab756e883c26dbbc010b4.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fbea9401fba59081a8670bd116312345f235474acd00d17b9d9a942bff675c13/metadata.json b/fbea9401fba59081a8670bd116312345f235474acd00d17b9d9a942bff675c13/metadata.json
index 1984de1f298c09eae6c288d1d03cc5c06279f4de..2d96d46e2fdebfa1e0c90f6c69a3c5c8becd126c 100644
--- a/fbea9401fba59081a8670bd116312345f235474acd00d17b9d9a942bff675c13/metadata.json
+++ b/fbea9401fba59081a8670bd116312345f235474acd00d17b9d9a942bff675c13/metadata.json
@@ -185,5 +185,35 @@
             "section_text": "Nature Metabolism (2025)\n\nStem Cell Research & Therapy (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "FigureS1.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/45d66f01f2942b49610935d4.pdf"
+        },
+        {
+            "title": "FigureS2.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/eb987ac33da0f698ccfb5dc4.pdf"
+        },
+        {
+            "title": "FigureS3.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/6bc000c97a8e351d5da32a17.pdf"
+        },
+        {
+            "title": "FigureS4.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/4762722f4ca5a7d3d117113b.pdf"
+        },
+        {
+            "title": "FigureS5.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/629a068a7315836026e531a8.pdf"
+        },
+        {
+            "title": "SupplementalNotes.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/f4f71efffd7ec2c5b1db0a9e.pdf"
+        },
+        {
+            "title": "SupplementaryTables.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3149275/v1/98d969e3f7aed257002848a0.xlsx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fe15eb2cd032d1bb4dc83a751895fc6d617c53866565e36ca440ac58bd05b638/metadata.json b/fe15eb2cd032d1bb4dc83a751895fc6d617c53866565e36ca440ac58bd05b638/metadata.json
index cd95e7b751ffac5aff6209342d208ddfddd26a42..2d74b70b6932e8f6e59157a20a0ffdf52a91e178 100644
--- a/fe15eb2cd032d1bb4dc83a751895fc6d617c53866565e36ca440ac58bd05b638/metadata.json
+++ b/fe15eb2cd032d1bb4dc83a751895fc6d617c53866565e36ca440ac58bd05b638/metadata.json
@@ -142,5 +142,11 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SipleCoastSI.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-3340271/v1/00f79008ae42b6f13d447fca.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/fe835bd622d094c7af5deb40228c4be8bf672084ccea7614d8d7761d7279c657/metadata.json b/fe835bd622d094c7af5deb40228c4be8bf672084ccea7614d8d7761d7279c657/metadata.json
index d41378234ed87d71d69d4f829d6c627c9e61ce65..38de2fb899f00ef531b0650a7ddececcf4a68483 100644
--- a/fe835bd622d094c7af5deb40228c4be8bf672084ccea7614d8d7761d7279c657/metadata.json
+++ b/fe835bd622d094c7af5deb40228c4be8bf672084ccea7614d8d7761d7279c657/metadata.json
@@ -117,5 +117,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "EntropyACSM.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-468139/v1/8fefde5d9664cd17853d4c0f.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/feea05672c2cdb6bc220418474b9f6fc3f7a83f70287346525502fd4ab284f66/metadata.json b/feea05672c2cdb6bc220418474b9f6fc3f7a83f70287346525502fd4ab284f66/metadata.json
index 3c23f1e762b62fd325666a1e03e51f129ad39e2c..a1f400b38f5ec087a4af2d2f8c54a809eee75725 100644
--- a/feea05672c2cdb6bc220418474b9f6fc3f7a83f70287346525502fd4ab284f66/metadata.json
+++ b/feea05672c2cdb6bc220418474b9f6fc3f7a83f70287346525502fd4ab284f66/metadata.json
@@ -166,5 +166,35 @@
             "section_text": "Nature Communications (2024)",
             "section_image": []
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/20422c383530ede195303fa7.docx"
+        },
+        {
+            "title": "SupplementaryData1.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/321e3b372e485ace50e98c93.xlsx"
+        },
+        {
+            "title": "SupplementaryData2.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/faa1921ef93223a2f7dbddb6.xlsx"
+        },
+        {
+            "title": "PhrynosomatidaeGeneMatrix.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/7e7efc1dbdd3961f669693bf.txt"
+        },
+        {
+            "title": "PhrynosomatidaeTree.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/392459714174ba445c97e942.txt"
+        },
+        {
+            "title": "Phrynosomatidae500Trees.txt",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/59b8c1de8d78a3eabe924039.txt"
+        },
+        {
+            "title": "RS.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-127587/v1/fa4800cc75c4fbd692656be1.pdf"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ff0b3007e6e9f85c26f5a05e99b2bd917d1b059ae4fc1678681a97f93d871006/metadata.json b/ff0b3007e6e9f85c26f5a05e99b2bd917d1b059ae4fc1678681a97f93d871006/metadata.json
index cd2b2895a3cb2f89eba9afe9ddcf0163bff95861..bdac5ab57109474e51bf9c830706360ea7fbfcbd 100644
--- a/ff0b3007e6e9f85c26f5a05e99b2bd917d1b059ae4fc1678681a97f93d871006/metadata.json
+++ b/ff0b3007e6e9f85c26f5a05e99b2bd917d1b059ae4fc1678681a97f93d871006/metadata.json
@@ -176,5 +176,39 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryTable1PlasmaGCMSMarch2024.xlsx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/55a202b19f24586b1d95621e.xlsx"
+        },
+        {
+            "title": "FigureS1InVivoLabellingMarch2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/a91cc5dd96e70e260a0e9ba7.pdf"
+        },
+        {
+            "title": "FigureS2MIMSEMregistrationmetricsMarch2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/248c3cea29a2c85176e844b5.pdf"
+        },
+        {
+            "title": "FigureS3MIMSEMLiverTissueScaleMarch2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/d43eec6e3eb0221183d3b76e.pdf"
+        },
+        {
+            "title": "FigureS4DLBenchmarksMarch2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/105a86c4ee11f6fb65b3a522.pdf"
+        },
+        {
+            "title": "FigureS5LiverDemographicsJan2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/efedd5e8e387f60c22353b75.pdf"
+        },
+        {
+            "title": "FIgureS6MitoLDERcontactsSpatialMetricsMarch2024.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/8bc6acea6a9fd388f4aceeff.pdf"
+        },
+        {
+            "title": "MaterialandMethodsFinalMarch2023.docx",
+            "link": "https://assets-eu.researchsquare.com/files/rs-4096781/v1/0a5d16205823cdee649f6aa5.docx"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ff88fa27b8e6d34d884a1e30151d8f43c09147c3a1fe877d8f260a0723891ca8/metadata.json b/ff88fa27b8e6d34d884a1e30151d8f43c09147c3a1fe877d8f260a0723891ca8/metadata.json
index 0904d24a4e3f176be3f13b97270a55b259a31eaa..51d6420e58dc8da04ad236ea833ff9f9b3ec7fce 100644
--- a/ff88fa27b8e6d34d884a1e30151d8f43c09147c3a1fe877d8f260a0723891ca8/metadata.json
+++ b/ff88fa27b8e6d34d884a1e30151d8f43c09147c3a1fe877d8f260a0723891ca8/metadata.json
@@ -163,5 +163,19 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformationFinal.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5099506/v1/e8360b049d7b9e02fb5ad6e3.pdf"
+        },
+        {
+            "title": "Demo1Linearslipsensingandmitigation.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5099506/v1/dd1ca9db22c73508843affda.mp4"
+        },
+        {
+            "title": "Demo2Rotationalslipdetectionandmitigation.mp4",
+            "link": "https://assets-eu.researchsquare.com/files/rs-5099506/v1/00e1145557c5cdccab509760.mp4"
+        }
     ]
 }
\ No newline at end of file
diff --git a/ffbf3c8a38baa418ba3b30abb130671bf01454a98bb1b2a446bd1f1fd8eb5a24/metadata.json b/ffbf3c8a38baa418ba3b30abb130671bf01454a98bb1b2a446bd1f1fd8eb5a24/metadata.json
index b89330e9e12f738ea0cd48558a16c0847446ff09..1d8cb3cb54dabda4ed36bfcb95ac0f376b1f6f42 100644
--- a/ffbf3c8a38baa418ba3b30abb130671bf01454a98bb1b2a446bd1f1fd8eb5a24/metadata.json
+++ b/ffbf3c8a38baa418ba3b30abb130671bf01454a98bb1b2a446bd1f1fd8eb5a24/metadata.json
@@ -150,5 +150,11 @@
                 "https://data:image/svg+xml;base64,<svg height="81" width="57" xmlns="http://www.w3.org/2000/svg"><g fill="none" fill-rule="evenodd"><path d="m17.35 35.45 21.3-14.2v-17.03h-21.3" fill="#989898"/><path d="m38.65 35.45-21.3-14.2v-17.03h21.3" fill="#747474"/><path d="m28 .5c-12.98 0-23.5 10.52-23.5 23.5s10.52 23.5 23.5 23.5 23.5-10.52 23.5-23.5c0-6.23-2.48-12.21-6.88-16.62-4.41-4.4-10.39-6.88-16.62-6.88zm0 41.25c-9.8 0-17.75-7.95-17.75-17.75s7.95-17.75 17.75-17.75 17.75 7.95 17.75 17.75c0 4.71-1.87 9.22-5.2 12.55s-7.84 5.2-12.55 5.2z" fill="#535353"/><path d="m41 36c-5.81 6.23-15.23 7.45-22.43 2.9-7.21-4.55-10.16-13.57-7.03-21.5l-4.92-3.11c-4.95 10.7-1.19 23.42 8.78 29.71 9.97 6.3 23.07 4.22 30.6-4.86z" fill="#9c9c9c"/><path d="m.2 58.45c0-.75.11-1.42.33-2.01s.52-1.09.91-1.5c.38-.41.83-.73 1.34-.94.51-.22 1.06-.32 1.65-.32.56 0 1.06.11 1.51.35.44.23.81.5 1.1.81l-.91 1.01c-.24-.24-.49-.42-.75-.56-.27-.13-.58-.2-.93-.2-.39 0-.73.08-1.05.23-.31.16-.58.37-.81.66-.23.28-.41.63-.53 1.04-.13.41-.19.88-.19 1.39 0 1.04.23 1.86.68 2.46.45.59 1.06.88 1.84.88.41 0 .77-.07 1.07-.23s.59-.39.85-.68l.91 1c-.38.43-.8.76-1.28.99-.47.22-1 .34-1.58.34-.59 0-1.13-.1-1.64-.31-.5-.2-.94-.51-1.31-.91-.38-.4-.67-.9-.88-1.48-.22-.59-.33-1.26-.33-2.02zm8.4-5.33h1.61v2.54l-.05 1.33c.29-.27.61-.51.96-.72s.76-.31 1.24-.31c.73 0 1.27.23 1.61.71.33.47.5 1.14.5 2.02v4.31h-1.61v-4.1c0-.57-.08-.97-.25-1.21-.17-.23-.45-.35-.83-.35-.3 0-.56.08-.79.22-.23.15-.49.36-.78.64v4.8h-1.61zm7.37 6.45c0-.56.09-1.06.26-1.51.18-.45.42-.83.71-1.14.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.36c.07.62.29 1.1.65 1.44.36.33.82.5 1.38.5.29 0 .57-.04.83-.13s.51-.21.76-.37l.55 1.01c-.33.21-.69.39-1.09.53-.41.14-.83.21-1.26.21-.48 0-.92-.08-1.34-.25-.41-.16-.76-.4-1.07-.7-.31-.31-.55-.69-.72-1.13-.18-.44-.26-.95-.26-1.52zm4.6-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.07.45-.31.29-.5.73-.58 1.3zm2.5.62c0-.57.09-1.08.28-1.53.18-.44.43-.82.75-1.13s.69-.54 1.1-.71c.42-.16.85-.24 1.31-.24.45 0 .84.08 1.17.23s.61.34.85.57l-.77 1.02c-.19-.16-.38-.28-.56-.37-.19-.09-.39-.14-.61-.14-.56 0-1.01.21-1.35.63-.35.41-.52.97-.52 1.67 0 .69.17 1.24.51 1.66.34.41.78.62 1.32.62.28 0 .54-.06.78-.17.24-.12.45-.26.64-.42l.67 1.03c-.33.29-.69.51-1.08.65-.39.15-.78.23-1.18.23-.46 0-.9-.08-1.31-.24-.4-.16-.75-.39-1.05-.7s-.53-.69-.7-1.13c-.17-.45-.25-.96-.25-1.53zm6.91-6.45h1.58v6.17h.05l2.54-3.16h1.77l-2.35 2.8 2.59 4.07h-1.75l-1.77-2.98-1.08 1.23v1.75h-1.58zm13.69 1.27c-.25-.11-.5-.17-.75-.17-.58 0-.87.39-.87 1.16v.75h1.34v1.27h-1.34v5.6h-1.61v-5.6h-.92v-1.2l.92-.07v-.72c0-.35.04-.68.13-.98.08-.31.21-.57.4-.79s.42-.39.71-.51c.28-.12.63-.18 1.04-.18.24 0 .48.02.69.07.22.05.41.1.57.17zm.48 5.18c0-.57.09-1.08.27-1.53.17-.44.41-.82.72-1.13.3-.31.65-.54 1.04-.71.39-.16.8-.24 1.23-.24s.84.08 1.24.24c.4.17.74.4 1.04.71s.54.69.72 1.13c.19.45.28.96.28 1.53s-.09 1.08-.28 1.53c-.18.44-.42.82-.72 1.13s-.64.54-1.04.7-.81.24-1.24.24-.84-.08-1.23-.24-.74-.39-1.04-.7c-.31-.31-.55-.69-.72-1.13-.18-.45-.27-.96-.27-1.53zm1.65 0c0 .69.14 1.24.43 1.66.28.41.68.62 1.18.62.51 0 .9-.21 1.19-.62.29-.42.44-.97.44-1.66 0-.7-.15-1.26-.44-1.67-.29-.42-.68-.63-1.19-.63-.5 0-.9.21-1.18.63-.29.41-.43.97-.43 1.67zm6.48-3.44h1.33l.12 1.21h.05c.24-.44.54-.79.88-1.02.35-.24.7-.36 1.07-.36.32 0 .59.05.78.14l-.28 1.4-.33-.09c-.11-.01-.23-.02-.38-.02-.27 0-.56.1-.86.31s-.55.58-.77 1.1v4.2h-1.61zm-47.87 15h1.61v4.1c0 .57.08.97.25 1.2.17.24.44.35.81.35.3 0 .57-.07.8-.22.22-.15.47-.39.73-.73v-4.7h1.61v6.87h-1.32l-.12-1.01h-.04c-.3.36-.63.64-.98.86-.35.21-.76.32-1.24.32-.73 0-1.27-.24-1.61-.71-.33-.47-.5-1.14-.5-2.02zm9.46 7.43v2.16h-1.61v-9.59h1.33l.12.72h.05c.29-.24.61-.45.97-.63.35-.17.72-.26 1.1-.26.43 0 .81.08 1.15.24.33.17.61.4.84.71.24.31.41.68.53 1.11.13.42.19.91.19 1.44 0 .59-.09 1.11-.25 1.57-.16.47-.38.85-.65 1.16-.27.32-.58.56-.94.73-.35.16-.72.25-1.1.25-.3 0-.6-.07-.9-.2s-.59-.31-.87-.56zm0-2.3c.26.22.5.37.73.45.24.09.46.13.66.13.46 0 .84-.2 1.15-.6.31-.39.46-.98.46-1.77 0-.69-.12-1.22-.35-1.61-.23-.38-.61-.57-1.13-.57-.49 0-.99.26-1.52.77zm5.87-1.69c0-.56.08-1.06.25-1.51.16-.45.37-.83.65-1.14.27-.3.58-.54.93-.71s.71-.25 1.08-.25c.39 0 .73.07 1 .2.27.14.54.32.81.55l-.06-1.1v-2.49h1.61v9.88h-1.33l-.11-.74h-.06c-.25.25-.54.46-.88.64-.33.18-.69.27-1.06.27-.87 0-1.56-.32-2.07-.95s-.76-1.51-.76-2.65zm1.67-.01c0 .74.13 1.31.4 1.7.26.38.65.58 1.15.58.51 0 .99-.26 1.44-.77v-3.21c-.24-.21-.48-.36-.7-.45-.23-.08-.46-.12-.7-.12-.45 0-.82.19-1.13.59-.31.39-.46.95-.46 1.68zm6.35 1.59c0-.73.32-1.3.97-1.71.64-.4 1.67-.68 3.08-.84 0-.17-.02-.34-.07-.51-.05-.16-.12-.3-.22-.43s-.22-.22-.38-.3c-.15-.06-.34-.1-.58-.1-.34 0-.68.07-1 .2s-.63.29-.93.47l-.59-1.08c.39-.24.81-.45 1.28-.63.47-.17.99-.26 1.54-.26.86 0 1.51.25 1.93.76s.63 1.25.63 2.21v4.07h-1.32l-.12-.76h-.05c-.3.27-.63.48-.98.66s-.73.27-1.14.27c-.61 0-1.1-.19-1.48-.56-.38-.36-.57-.85-.57-1.46zm1.57-.12c0 .3.09.53.27.67.19.14.42.21.71.21.28 0 .54-.07.77-.2s.48-.31.73-.56v-1.54c-.47.06-.86.13-1.18.23-.31.09-.57.19-.76.31s-.33.25-.41.4c-.09.15-.13.31-.13.48zm6.29-3.63h-.98v-1.2l1.06-.07.2-1.88h1.34v1.88h1.75v1.27h-1.75v3.28c0 .8.32 1.2.97 1.2.12 0 .24-.01.37-.04.12-.03.24-.07.34-.11l.28 1.19c-.19.06-.4.12-.64.17-.23.05-.49.08-.76.08-.4 0-.74-.06-1.02-.18-.27-.13-.49-.3-.67-.52-.17-.21-.3-.48-.37-.78-.08-.3-.12-.64-.12-1.01zm4.36 2.17c0-.56.09-1.06.27-1.51s.41-.83.71-1.14c.29-.3.63-.54 1.01-.71.39-.17.78-.25 1.18-.25.47 0 .88.08 1.23.24.36.16.65.38.89.67s.42.63.54 1.03c.12.41.18.84.18 1.32 0 .32-.02.57-.07.76h-4.37c.08.62.29 1.1.65 1.44.36.33.82.5 1.38.5.3 0 .58-.04.84-.13.25-.09.51-.21.76-.37l.54 1.01c-.32.21-.69.39-1.09.53s-.82.21-1.26.21c-.47 0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>"
             ]
         }
+    ],
+    "supplementary_files": [
+        {
+            "title": "SupplementaryInformation.pdf",
+            "link": "https://assets-eu.researchsquare.com/files/rs-1650728/v1/0897ea801037afa774007b9d.pdf"
+        }
     ]
 }
\ No newline at end of file