Duplicate from pzweuj/EVOScore-2

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README.md

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+---
+language:
+- en
+tags:
+- biology
+- ESM
+- language-model
+- protein
+- VEP
+pretty_name: EVOScore-2
+size_categories:
+- 100M<n<1B
+license: mit
+---
+
+# Proteome-wide VESM-3B Variant Effect Scores (MIT Clean Mirror)
+
+![License: MIT](https://img.shields.io/badge/License-MIT-yellow.svg)
+![Commercial Status](https://img.shields.io/badge/Status-Commercial--Safe-brightgreen)
+
+## ⚠️ Compliance & Mirror Notice
+
+This repository is a **strict subset** of the original [ntranoslab/vesm_scores](https://huggingface.co/datasets/ntranoslab/vesm_scores). 
+
+To ensure commercial compliance and safety, all non-commercial components (VESM3, Sequence-only VESM3, and VESM++) have been **permanently removed** from this mirror. 
+
+**This repository contains ONLY the `VESM_3B` predictions**, which are based on the ESM2-3B architecture and explicitly released under the MIT License.
+
+---
+
+## Dataset Description
+
+This repository provides precomputed **proteome-wide (UniProtKB, hg19, and hg38) variant-effect prediction scores** using the **VESM_3B** model.
+
+### Included Model
+* **VESM_3B:** A protein language model based on **ESM2 (3B parameter)** architecture. 
+
+*(Note: The original VESM3 and VESM++ models based on ESM3 have been excluded from this repository).*
+
+For more scientific details, please refer to the original GitHub repo: https://github.com/ntranoslab/vesm
+
+## Files Included
+* `hg38_VESM_3B_scores.parquet.gzip`
+* `hg19_VESM_3B_scores.parquet.gzip`
+* `hg38_VESM_3B_scores.vcf.gz`
+* `hg19_VESM_3B_scores.vcf.gz`
+* *(And any other Uniprot/metadata files strictly related to VESM_3B)*
+
+## Threshold Recommend
+
+| P_threshold     | <-11.6    |
+| --------------- | ----------- |
+| **B_threshold** | **>-8.5** |
+
+## License <a name="license"></a>
+
+The data provided in this repository is distributed under the **MIT License**.
+
+> **Attribution:**
+> This dataset is a mirror of the VESM_3B predictions generated by Ntranos Lab.
+> While the original repository contained mixed licenses, the content hosted here is exclusively sourced from the MIT-licensed portion.

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