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README.md
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3794 3D structural MRI brain scans (T1-weighted MPRAGE NIfTI files) from 2607 individuals included in five publicly available datasets: [IXI](https://brain-development.org/ixi-dataset/), [DLBS](https://fcon_1000.projects.nitrc.org/indi/retro/dlbs.html), [NKI-RS](https://fcon_1000.projects.nitrc.org/indi/enhanced/sharing_neuro.html), [OASIS-1](https://sites.wustl.edu/oasisbrains/home/oasis-1/), and [OASIS-2](https://sites.wustl.edu/oasisbrains/home/oasis-2/). Subjects have a mean age of 45 ± 24. 3773 scans come from cognitively normal individuals and 261 scans from individuals with an Alzheimer's disease clinical diagnosis. Scans dimensions are 113x137x113, 1.5mm^3 resolution, aligned to MNI152 space (see methods).
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Scans
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# License
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```
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# Example usage
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```
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# install Hugging Face Datasets library
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pip install datasets
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# Methods
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## Image processing
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T1-weighted structural MRI scans were processed with [CAT12](https://neuro-jena.github.io/cat12-help/) ([Gaser et al, 2024](https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae049/7727520)). The image processing steps were:
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- correct for bias, noise and intensity
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- mask to brain-only (gray matter + white matter + CSF)
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- register to ICBM 2009c Nonlinear Asymmetric space (MNI152NLin2009cAsym 1.5mm^3) using linear affine registration with 12 degrees of freedom in [FSL FLIRT](https://fsl.fmrib.ox.ac.uk/fsl/docs/#/registration/flirt/index) ('flirt -in t1.nii.gz -ref mni_icbm152_t1_tal_nlin_asym_09c_brain_1_5_mm.nii.gz -dof 12 -noresampblur').
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author = {Jesse Brown and Clayton Young},
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title = {Brain-Structure: A Collection of Processed Structural MRI Scans},
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year = {2025},
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url = {
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note = {Version 1.0},
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publisher = {
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}
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```
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---
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license: odc-by
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language:
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- en
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task_categories:
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- image-classification
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tags:
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- medical
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- brain-data
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- mri
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pretty_name: 3D Brain Structure MRI Scans
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---
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# Dataset Description
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**Homepage:** [Radiata](https://radiata.ai/)
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**Contact:** [Jesse Brown](https://huggingface.co/jesse-radiata)
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## Dataset Summary
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3794 3D structural MRI brain scans (T1-weighted MPRAGE NIfTI files) from 2607 individuals included in five publicly available datasets: [IXI](https://brain-development.org/ixi-dataset/), [DLBS](https://fcon_1000.projects.nitrc.org/indi/retro/dlbs.html), [NKI-RS](https://fcon_1000.projects.nitrc.org/indi/enhanced/sharing_neuro.html), [OASIS-1](https://sites.wustl.edu/oasisbrains/home/oasis-1/), and [OASIS-2](https://sites.wustl.edu/oasisbrains/home/oasis-2/). Subjects have a mean age of 45 ± 24. 3773 scans come from cognitively normal individuals and 261 scans from individuals with an Alzheimer's disease clinical diagnosis. Scans dimensions are 113x137x113, 1.5mm^3 resolution, aligned to MNI152 space (see methods).
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Scans have been processed and all protected health information (PHI) is excluded. Only the skull-stripped scan, integer age, biological sex, clinical diagnosis, and scan metadata are included. [Radiata](https://radiata.ai/) compiles and processes publicly available neuroimaging datasets to create this open, unified, and harmonized dataset. For more information see https://radiata.ai/public-studies. Example uses including developing foundation-like models or tailored models for brain age prediction and disease classification.
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# License
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```
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# Example usage
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```
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# install Hugging Face Datasets library
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pip install datasets
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# Methods
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## Image processing
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T1-weighted structural MRI scans were processed with [CAT12](https://neuro-jena.github.io/cat12-help/) ([Gaser et al, 2024](https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae049/7727520)). The image processing steps were:
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- correct for bias, noise, and intensity
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- mask to brain-only (gray matter + white matter + CSF)
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- register to ICBM 2009c Nonlinear Asymmetric space (MNI152NLin2009cAsym 1.5mm^3) using linear affine registration with 12 degrees of freedom in [FSL FLIRT](https://fsl.fmrib.ox.ac.uk/fsl/docs/#/registration/flirt/index) ('flirt -in t1.nii.gz -ref mni_icbm152_t1_tal_nlin_asym_09c_brain_1_5_mm.nii.gz -dof 12 -noresampblur').
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author = {Jesse Brown and Clayton Young},
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title = {Brain-Structure: A Collection of Processed Structural MRI Scans},
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year = {2025},
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url = {https://huggingface.co/datasets/radiata-ai/brain-structure},
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note = {Version 1.0},
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publisher = {Hugging Face}
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}
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```
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