doc_id stringlengths 13 82 | source_group stringclasses 2
values | source_file stringclasses 7
values | pmcid stringlengths 9 11 ⌀ | doi stringlengths 0 121 ⌀ | title stringlengths 0 726 ⌀ | year stringclasses 30
values | text stringlengths 500 60k | text_length_chars int64 500 60k | words int32 100 11.6k ⌀ | has_abstract bool 2
classes | has_refs bool 2
classes | main_field stringlengths 6 61 | is_biology bool 1
class | is_nitrogen bool 2
classes | bio_labels stringlengths 2 1.13k | nitrogen_labels stringlengths 2 1.01k | confidence float64 0 0.99 ⌀ | metadata_json stringlengths 26 42.3k ⌀ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
uniprotkb_text_metadata_unified:8bfcd8bb397b3247ca559ecd2b1d2579 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Uncharacterized protein IIV3-013L
Organism: Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus).
TaxID: 345201
Genes: ORFNames=IIV3-013L;
## Subcellular Location
Host membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. ------------------------------------------------------------------... | 711 | null | null | null | Molecular Biology | true | false | [Cell biology, Virology] | [] | null | {'accessions': [Q197E7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:b90802e3734ac9e3be5b57ef55a4fc9a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Uncharacterized protein 034R
Organism: Frog virus 3 (isolate Goorha) (FV-3).
TaxID: 654924
Genes: ORFNames=FV3-034R;
## Subcellular Location
Host membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. --------------------------------------------------------------------------- Copyrighted by the UniProt ... | 674 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics] | [] | null | {'accessions': [Q6GZU2], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:2cac2469fbc525843f0e49297f2a1f52 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Transmembrane protein 049L
Organism: Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
TaxID: 176652
Genes: ORFNames=IIV6-049L;
## Subcellular Location
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. --------------------------------------------------------------------------- Copyri... | 760 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics] | [] | null | {'accessions': [Q91G50], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:80edf9acd4189918cc0705416278c110 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Putative myristoylated protein 053R
Organism: Frog virus 3 (isolate Goorha) (FV-3).
TaxID: 654924
Genes: ORFNames=FV3-053R;
## Function
May play a critical role in virion formation. Essential for virus replication in vitro. {ECO:0000269|PubMed:20633916}.
## Subcellular Location
Host membrane {ECO:0000305}; Multi-pa... | 836 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [Q6GZS3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:96f1e0663688f0d6c19bdc4dc446a0a3 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Uncharacterized protein 075L
Organism: Frog virus 3 (isolate Goorha) (FV-3).
TaxID: 654924
Genes: ORFNames=FV3-075L;
## Subcellular Location
Host membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. --------------------------------------------------------------------------- Copyrighted by the UniProt C... | 711 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics] | [] | null | {'accessions': [Q6GZQ0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:d3118c687e25d2fe8b81fe99ee2d3b0d | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Olfactory receptor 10D1B {ECO:0000305}
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Or10d1b {ECO:0000312|MGI:MGI:2660716}; Synonyms=Mor224-8 {ECO:0000312|MGI:MGI:2660716}, Olfr149 {ECO:0000312|MGI:MGI:2660716}, Olfr7;
## Function
Odorant receptor. {ECO:0000305}.
## Subcellular Location
Cell membrane {EC... | 1,026 | null | null | null | Biology | true | false | [Cell biology, Molecular Biology, Genetics] | [] | null | {'accessions': [Q60888, B9EJ08, Q7TRA8, Q8VEP7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTI... |
uniprotkb_text_metadata_unified:bd6a417088c5e042aa14dcc40a0271a2 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-13L
Organism: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
TaxID: 10500
Genes: OrderedLocusNames=Mal-018;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host membrane ... | 519 | null | null | null | Virology | true | false | [Virology, Cell biology] | [] | null | {'accessions': [P0C9K1], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:bf50f842baa82ed33fa3782add69c358 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-1L
Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV).
TaxID: 10498
Genes: OrderedLocusNames=BA71V-008; ORFNames=L270L;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular... | 578 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [P18560], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:94befe2a25cb83864b7108d067a47018 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-1L
Organism: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
TaxID: 10500
Genes: OrderedLocusNames=Mal-005;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host membrane {... | 563 | null | null | null | Virology | true | false | [Virology, Cell biology, Molecular biology] | [] | null | {'accessions': [P0C9G3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:613dc31cff5c73966e6bb6fa8164574b | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-1L
Organism: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
TaxID: 561444
Genes: OrderedLocusNames=War-006;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host membran... | 566 | null | null | null | Virology | true | false | [Virology, Cell biology, Molecular biology] | [] | null | {'accessions': [P0C9G1], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:023d95e00684f28d7552e6d7a9aaf0c4 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-4L-B
Organism: African swine fever virus (isolate Portugal/Lis 57/1957) (ASFV).
TaxID: 10499
Genes: ORFNames=LIS124-2;
## Function
Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment. {ECO:0000250|UniProtKB:P18558}.
## Subcellular Location
Virion {ECO:0000250|UniProtKB:P... | 641 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [P26708], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:7aa7a989c78691133af24dc59c500daa | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-4L
Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV).
TaxID: 10498
Genes: OrderedLocusNames=BA71V-011, BA71V-012; ORFNames=XP124L;
## Function
Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment. {ECO:0000269|PubMed:15016891}.
## Subce... | 733 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [P18558], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:dc3d381be79ca07339f2e9ce88fa9da2 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-6L
Organism: African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
TaxID: 10500
Genes: OrderedLocusNames=Mal-011;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host endoplasmi... | 520 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [P0C9H9], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:8159774f14bccb12d8e0b2e698430b65 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-6L
Organism: African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV).
TaxID: 561443
Genes: OrderedLocusNames=Pret-015;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location... | 550 | null | null | null | Virology | true | false | [Virology, Cell biology, Proteomics] | [] | null | {'accessions': [P0C9I0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:463c44c74cd732da2244e58f2fc2d8bb | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 110-9L
Organism: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
TaxID: 561444
Genes: OrderedLocusNames=War-019;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host membran... | 535 | null | null | null | Virology | true | false | [Virology, Cell biology, Molecular biology] | [] | null | {'accessions': [P0C9I9], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:700133a8d121d954008ca8adb55af3db | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 13S globulin seed storage protein {ECO:0000303|PubMed:18980324}
Organism: Fagopyrum tataricum (Tartarian buckwheat) (Polygonum tataricum).
TaxID: 62330
## Function
Seed storage protein. {ECO:0000305}.
## Tissue Specificity
Expressed in seeds (at protein level). {ECO:0000269|PubMed:15277744}.
## Keywords
Allergen, ... | 594 | null | null | null | Plant Biology | true | false | [Plant biochemistry, Plant physiology, Proteomics] | [] | null | {'accessions': [A9NJG2, Q8LGR7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': 'Causes an allergic reaction in human (PubMed:15277744, PubMed:16717422, PubMed:18980324, PubMed:20431913, PubMed:21571740, PubMed:22449541). Natural protein binds to IgE in all 5 buckwheat- allergic patients tested. Natural protein... |
uniprotkb_text_metadata_unified:9add64116c24d7a9c4f953196733972b | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3-like protein GF14 nu
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=GRF7; OrderedLocusNames=At3g02520; ORFNames=F16B3.15;
## Function
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
## Su... | 1,106 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics, Proteomics] | [] | null | {'accessions': [Q96300], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:9caf423c21fc2ee1e92e2cf733aa6233 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein beta/alpha
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
TaxID: 8364
Genes: Name=ywhab; ORFNames=TTpA010k20.1;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partner... | 1,538 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein function, Signal transduction] | [] | null | {'accessions': [Q5XGC8, Q28HK2], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:6b5004a4bda5b40cdb0a08341c1edf03 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein epsilon
Organism: Homo sapiens (Human).
TaxID: 9606
Genes: Name=YWHAE;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:21189250). Binds to a large number of partners, usually by recognition of a phosphoserine or ph... | 6,617 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics, Signal transduction, Protein-protein interactions, Gene regulation, Immune response] | [] | null | {'accessions': [P62258, B3KY71, D3DTH5, P29360, P42655, Q4VJB6, Q53XZ5, Q63631, Q7M4R4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P62258-1; Sequence=Displayed; Name=SV; IsoId=P62258-2; Sequence=VSP_040621;', 'BIOPHY... |
uniprotkb_text_metadata_unified:0716f573eac16106fe03b4321fd73b10 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein gamma {ECO:0000305}
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Ywhag {ECO:0000312|MGI:MGI:108109};
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition ... | 5,351 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction, Protein localization, Protein degradation, Immune response, Neuronal function] | [] | null | {'accessions': [P61982, O70457, P35214, Q3UFD6, Q4FK44, Q9UDP2, Q9UN99], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'D... |
uniprotkb_text_metadata_unified:a80b9f7cfe170b0c81decb4e3578f791 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein gamma {ECO:0000250|UniProtKB:P61981}
Organism: Ovis aries (Sheep).
TaxID: 9940
Genes: Name=YWHAG {ECO:0000250|UniProtKB:P61981};
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually... | 2,109 | null | null | null | Cell Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction, Mitochondrial function] | [] | null | {'accessions': [P68253, P29359], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:407797749eb21dc142753a93b1f0aab1 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein sigma
Organism: Ovis aries (Sheep).
TaxID: 9940
Genes: Name=SFN;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Bi... | 3,944 | null | null | null | Cell Biology | true | false | [Cell biology, Molecular biology, Protein-protein interactions, Signal transduction, Cell cycle regulation, Apoptosis, Immune response, Epithelial cell biology, Protein localization, Transcription regulation] | [] | null | {'accessions': [O77642], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:bba84b4c23f9d82235a53a67c389a267 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein theta
Organism: Xenopus laevis (African clawed frog).
TaxID: 8355
Genes: Name=ywhaq;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosph... | 723 | null | null | null | Cell Biology | true | false | [Cell biology, Protein function, Signal transduction] | [] | null | {'accessions': [Q52M98], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:a29a312a95bb5cee7ac3f3a82d876951 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta/delta
Organism: Bos taurus (Bovine).
TaxID: 9913
Genes: Name=YWHAZ;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:7931346). Binds to a large number of partners, usually by recognition of a phosphoserine or p... | 4,327 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction, Transcription regulation, Cytoskeleton, Neurobiology, Immunology, Developmental biology] | [] | null | {'accessions': [P63103, P29213, P29312, Q3ZCF9], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTI... |
uniprotkb_text_metadata_unified:56030a46e6b6f90ab6d7c0f278bc8144 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta/delta
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Ywhaz;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine... | 4,980 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction, Transcription regulation, Cytoskeleton, Neurobiology, Developmental biology, Immunology] | [] | null | {'accessions': [P63101, P35215, P70197, P97286, Q3TSF1, Q5EBQ1], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE':... |
uniprotkb_text_metadata_unified:1093369fae7aeaa085b23477f9d3bb75 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta/delta
Organism: Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
TaxID: 9601
Genes: Name=YWHAZ;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of... | 1,521 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction, Protein phosphorylation] | [] | null | {'accessions': [Q5R651], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:87bc45f9a530d2c3528d08aaa1e39f6a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta/delta
Organism: Ovis aries (Sheep).
TaxID: 9940
Genes: Name=YWHAZ;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine mo... | 1,513 | null | null | null | Biology | true | false | [Cell biology, Molecular Biology, Proteomics] | [] | null | {'accessions': [P29361], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:869f43faed273cb2d889188343fef533 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta
Organism: Xenopus laevis (African clawed frog).
TaxID: 8355
Genes: Name=ywhaz;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phospho... | 1,037 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction] | [] | null | {'accessions': [Q91896, O57469], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:e09c4bff8c0a396006d6ff0b5c131697 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein zeta
Organism: Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
TaxID: 8364
Genes: Name=ywhaz; ORFNames=TTpA004p03.1;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usu... | 1,464 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction] | [] | null | {'accessions': [Q6P4Z5, Q28CE4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:ddaca8d6e054e9eaef38b098304b86ec | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3-like protein
Organism: Dictyostelium discoideum (Social amoeba).
TaxID: 44689
Genes: Name=fttB; ORFNames=DDB_G0269138;
## Keywords
Reference proteome.
## GO
GO; GO:0005938; C:cell cortex; IDA:dictyBase.
GO; GO:0005813; C:centrosome; IDA:dictyBase.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005829; ... | 1,620 | null | null | null | Cell Biology | true | false | [Cell biology, Molecular biology, Proteomics] | [] | null | {'accessions': [P54632, Q1ZXP9], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:25d3aab45d561d9069a6464f9b94db58 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein beta/alpha-B
Organism: Xenopus laevis (African clawed frog).
TaxID: 8355
Genes: Name=ywhab-b;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine ... | 745 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein function, Signal transduction] | [] | null | {'accessions': [Q8AVQ3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:a13e6dec30d34f023343fa5aa54a60db | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 14-3-3 protein gamma-B
Organism: Xenopus laevis (African clawed frog).
TaxID: 8355
Genes: Name=ywhag-b;
## Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or ph... | 945 | null | null | null | Biology | true | false | [Cell biology, Protein-protein interactions, Signal transduction] | [] | null | {'accessions': [Q6NRY9], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:cb270b6e49e7cd4644f284cbeb137105 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Lectin-like protein BA14k
Organism: Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) (Ochrobactrum anthropi).
TaxID: 439375
Genes: OrderedLocusNames=Oant_3884;
## Function
Has immunoglobulin-binding and hemagglutination properties, and can bind t... | 793 | null | null | null | Microbiology | true | false | [Cell biology, Immunology, Microbial pathogenesis] | [] | null | {'accessions': [A6X5T5], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:97c58812433577b2204a3c23003d4ee0 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Lectin-like protein BA14k
Organism: Brucella canis (strain ATCC 23365 / NCTC 10854 / RM-666).
TaxID: 483179
Genes: OrderedLocusNames=BCAN_B0743;
## Function
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysacchar... | 707 | null | null | null | Microbiology | true | false | [Cell biology, Immunology, Microbial pathogenesis] | [] | null | {'accessions': [A9MC22], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:8e5b835775486a796577ed157602885a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Lectin-like protein BA14k
Organism: Brucella melitensis biotype 1 (strain ATCC 23456 / CCUG 17765 / NCTC 10094 / 16M).
TaxID: 224914
Genes: OrderedLocusNames=BMEII0552;
## Function
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS bio... | 731 | null | null | null | Microbiology | true | false | [Cell biology, Immunology, Microbial pathogenesis] | [] | null | {'accessions': [Q7CNS4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:d7fc3cf56e68244dc22806946a2f6ed0 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Lectin-like protein BA14k
Organism: Brucella suis (strain ATCC 23445 / NCTC 10510).
TaxID: 470137
Genes: OrderedLocusNames=BSUIS_B0727;
## Function
Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide trans... | 678 | null | null | null | Microbiology | true | false | [Cell biology, Immunology, Microbial pathogenesis] | [] | null | {'accessions': [A9WZ33], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:dbb23d792080ca8ccc249b9621f65fb6 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Exo-alpha-(1->6)-L-arabinofuranosidase
Organism: Bifidobacterium longum.
TaxID: 216816
Genes: Name=afuB {ECO:0000303|PubMed:21851513};
## Function
Catalyzes the hydrolysis of p-nitrophenyl-alpha-L- arabinofuranoside (pNP-alphaL-Af) and the hydrolysis of the terminal alpha-L-arabinofuranoside at the C20 position of g... | 1,138 | null | null | null | Biochemistry | true | false | [Enzymology, Carbohydrate metabolism, Glycosidase] | [] | null | {'accessions': [E7CY70], 'cc_topics': {'ACTIVITY REGULATION': 'Completely inhibited by Cu(2+) and partially inhibited by Co(2+) and Ba(2+). {ECO:0000269|PubMed:21851513}.', 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: KM=0.21 mM for p-nitrophenyl-alpha-L-arabinof... |
uniprotkb_text_metadata_unified:7d89de13dd12db8edeffebd6ffeba617 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Popy Class I histocompatibility antigen, A-1 alpha chain
Organism: Pongo pygmaeus (Bornean orangutan).
TaxID: 9600
## Function
Involved in the presentation of foreign antigens to the immune system.
## Subcellular Location
Membrane; Single-pass type I membrane protein.
## Keywords
Disulfide bond, Glycoprotein, Immu... | 1,543 | null | null | null | Immunology | true | false | [Immunology, Cell biology, Molecular biology] | [] | null | {'accessions': [P16211], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:4f17f16dfa49def0a770fa339ef18865 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Saoe class I histocompatibility antigen, A alpha chain
Organism: Saguinus oedipus (Cotton-top tamarin) (Oedipomidas oedipus).
TaxID: 9490
## Function
Involved in the presentation of foreign antigens to the immune system.
## Subcellular Location
Membrane; Single-pass type I membrane protein.
## Keywords
Disulfide b... | 1,566 | null | null | null | Immunology | true | false | [Immunology, Cell biology] | [] | null | {'accessions': [P30515], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:3de312a570cc20121c088beb6591d245 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Probable aminotransferase ACS10
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=ACS10; OrderedLocusNames=At1g62960; ORFNames=F16P17.11;
## Function
Probable aminotransferase. Does not have 1-aminocyclopropane- 1-carboxylate synthase (ACS) activity, suggesting that it is not involved in ethy... | 794 | null | null | null | Biology | true | false | [Biochemistry, Plant biology, Molecular biology] | [] | null | {'accessions': [Q9LQ10], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': 'Contains a Gln instead of a Glu in position 176 and a Phe residue instead of a Tyr in position 209; th... |
uniprotkb_text_metadata_unified:1c0ce401852b74dc97004f46c9eba60a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 1-aminocyclopropane-1-carboxylate synthase
Organism: Dianthus caryophyllus (Carnation) (Clove pink).
TaxID: 3570
Genes: Name=ACS2; Synonyms=CARACC;
## Function
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
## Pathway
Alkene biosynthesis; ethylene bios... | 1,093 | null | null | null | Plant Biology | true | false | [Plant biochemistry, Plant physiology, Molecular biology] | [] | null | {'accessions': [P27486], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + S-methyl-5\'-thioadenosine + H(+); Xref=Rhea:RHE... |
uniprotkb_text_metadata_unified:d63bc5af3f6d83fbc76381e3adc38f9b | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 1-aminocyclopropane-1-carboxylate synthase
Organism: Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
TaxID: 3916
Genes: Name=ACS5;
## Function
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
## Pathway
Alkene biosynthesis; ethylene biosynthes... | 1,107 | null | null | null | Plant Biology | true | false | [Plant biochemistry, Plant physiology, Molecular biology] | [] | null | {'accessions': [Q01912], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + S-methyl-5\'-thioadenosine + H(+); Xref=Rhea:RHE... |
uniprotkb_text_metadata_unified:7f3d722dc8853e1a1b7ec0e80a951087 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Putative 1-aminocyclopropane-1-carboxylate deaminase
Organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
TaxID: 186497
Genes: OrderedLocusNames=PF0010;
## Catalytic Activity
Reaction=1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+); Xref=Rhea:RHEA:16933, ChEBI:CHEBI:15377,... | 622 | null | null | null | Biochemistry | true | false | [Enzymology, Proteomics, Molecular biology] | [] | null | {'accessions': [Q8U4R3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+); Xref=Rhea:RHEA:16933, ChEBI:CHEBI:15377, Ch... |
uniprotkb_text_metadata_unified:cb152852f59f20699c08ec9045ae900c | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 1-aminocyclopropane-1-carboxylate synthase-like protein 1
Organism: Bos taurus (Bovine).
TaxID: 9913
Genes: Name=ACCS;
## Function
Does not catalyze the synthesis of 1-aminocyclopropane-1- carboxylate but is capable of catalyzing the deamination of L- vinylglycine. {ECO:0000250|UniProtKB:Q96QU6}.
## Keywords
Pyrido... | 543 | null | null | null | Biochemistry | true | false | [Enzymology, Protein function, Metabolism] | [] | null | {'accessions': [Q5E9H2], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': 'Similar to plant 1-aminocyclopropane-1-carboxylate synthases but lacks a number of residues which are ... |
uniprotkb_text_metadata_unified:3c49a64656ed9bf4a6fd461917a88c6b | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Replication protein 1a
Organism: Broad bean mottle virus.
TaxID: 12301
Genes: ORFNames=ORF1a;
## Function
Involved in the virus replication. Contains a helicase domain and a methyltransferase domain. The methyltransferase domain is probably involved in viral RNA capping.
## Subcellular Location
Host endoplasmic ret... | 1,082 | null | null | null | Virology | true | false | [Molecular Biology, Virology, Cell biology] | [] | null | {'accessions': [Q00020], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:2371a3bb53fcedc5568f618aedf3a463 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Replication protein 1a
Organism: Peanut stunt virus (strain J) (PSV).
TaxID: 12314
Genes: ORFNames=ORF1a;
## Function
Involved in the virus replication. Contains a helicase domain and a methyltransferase domain. The methyltransferase domain is probably involved in viral RNA capping. Involved in the formation of ER m... | 1,225 | null | null | null | Virology | true | false | [Molecular Biology, Cell biology, Virology] | [] | null | {'accessions': [P28726], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:ac43fd57a9d6d5a653e107c8e9040dd4 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Replication protein 1a
Organism: Tobacco streak virus (strain WC) (TSV).
TaxID: 12318
## Function
Involved in the virus replication. Contains a helicase domain and a methyltransferase domain. The methyltransferase domain is probably involved in viral RNA capping. Involved in the formation of ER membrane spherular in... | 1,202 | null | null | null | Virology | true | false | [Molecular Biology, Cell biology, Virology] | [] | null | {'accessions': [P89680], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:10e7630c50614f7f7a30d5317c5b9f6d | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Patr class I histocompatibility antigen, C alpha chain
Organism: Pan troglodytes (Chimpanzee).
TaxID: 9598
## Function
Involved in the presentation of foreign antigens to the immune system.
## Subcellular Location
Membrane; Single-pass type I membrane protein.
## Keywords
Disulfide bond, Glycoprotein, Immunity, Me... | 1,550 | null | null | null | Immunology | true | false | [Immunology, Cell biology, Proteomics] | [] | null | {'accessions': [P30686], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:e06f24e0f7b0ac0362f0e0c0122f8809 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 1-Cys peroxiredoxin
Organism: Onchocerca volvulus.
TaxID: 6282
Genes: Name=TSA;
## Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. {E... | 973 | null | null | null | Biology | true | false | [Biochemistry, Cell biology, Molecular Biology] | [] | null | {'accessions': [P52570], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=a hydroperoxide + [protein]-dithiol = [protein]-disulfide + an alcohol + H2O; Xref=Rhea:RHEA:10008, Rhea:RHEA-... |
uniprotkb_text_metadata_unified:df1f901d31a14eae0e105311e288f092 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Fructan 1-exohydrolase {ECO:0000312|EMBL:ACI16119.1}
Organism: Aegilops speltoides (Goatgrass) (Triticum speltoides).
TaxID: 4573
Genes: Name=1-FEH {ECO:0000250|UniProtKB:Q84PN8};
## Function
Hydrolyzes inulin-type beta-(2,1)-fructans. May play a role as a beta-(2,1)-trimmer during graminan biosynthesis (By similari... | 764 | null | null | null | Biochemistry | true | false | [Enzymology, Molecular biology, Plant biology] | [] | null | {'accessions': [B6DZD1], 'cc_topics': {'ACTIVITY REGULATION': 'Inhibited by sucrose. {ECO:0000250|UniProtKB:Q84PN8}.', 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=Hydrolysis of terminal, non-reducing (2->1)-linked beta-D- ... |
uniprotkb_text_metadata_unified:30e448bc28afa126f79a822e772d1e4f | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Metalloendoproteinase 1-MMP {ECO:0000303|PubMed:10574937}
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=1MMP {ECO:0000303|PubMed:10574937}; OrderedLocusNames=At4g16640 {ECO:0000312|Araport:AT4G16640}; ORFNames=dl4345c {ECO:0000312|EMBL:CAB10439.1};
## Function
Matrix metalloproteinases (M... | 1,836 | null | null | null | Biology | true | false | [Cell biology, Proteomics, Plant biology] | [] | null | {'accessions': [O23507, Q84W77, Q8LET7], 'cc_topics': {'ACTIVITY REGULATION': 'Inhibited by human TIMP-1 and TIMP-2 and by the peptide hydroxamate inhibitor (BB-94) (PubMed:10574937). Repressed by acetohydroxamic acid (AHA) (PubMed:24156403). {ECO:0000269|PubMed:10574937, ECO:0000269|PubMed:24156403}.', 'ALLERGEN': NUL... |
uniprotkb_text_metadata_unified:d9361230ac6f673dc08f95922415a296 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Uncharacterized protein 234R
Organism: Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
TaxID: 176652
Genes: ORFNames=IIV6-234R;
## Subcellular Location
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. --------------------------------------------------------------------------- Cop... | 673 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics] | [] | null | {'accessions': [Q91FT8], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:01bd06ec7db3443a80e17308df62d053 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 2,5-diketocamphane 1,2-monooxygenase 2 {ECO:0000305|PubMed:23524667}
Organism: Pseudomonas putida (Arthrobacter siderocapsulatus).
TaxID: 303
Genes: Name=camE25-2 {ECO:0000303|PubMed:23524667, ECO:0000312|EMBL:BAN13304.1};
## Function
Involved in the degradation and assimilation of (+)-camphor, which allows P.putida... | 1,760 | null | null | null | Biochemistry | true | false | [Enzymology, Metabolism, Microbiology] | [] | null | {'accessions': [M5AWY0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'pH dependence: Optimum pH is 8.0. {ECO:0000269|PubMed:23524667};', 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=(1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)... |
uniprotkb_text_metadata_unified:9b158c73fd4812dc7a18327b05324403 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 {ECO:0000305}
Organism: Caenorhabditis elegans.
TaxID: 6239
Genes: Name=pptr-1 {ECO:0000312|WormBase:W08G11.4}; ORFNames=W08G11.4 {ECO:0000312|WormBase:W08G11.4};
## Function
Probable regulatory subunit of serine/threonine-protein phosphatase let-92 w... | 2,797 | null | null | null | Molecular Biology | true | false | [Genetics, Cell biology, Developmental biology, Signal transduction] | [] | null | {'accessions': [O18178], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': 'Mutants ... |
uniprotkb_text_metadata_unified:ffc92d931c23f6831e37b2b7ed942f20 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Organism: Rattus norvegicus (Rat).
TaxID: 10116
Genes: Name=Ppp2r5b; Synonyms=LOC100909468 {ECO:0000312|RGD:727786}; ORFNames=rCG_47223 {ECO:0000312|EMBL:EDM12588.1};
## Function
As the regulatory component of the serine/threonine-protein... | 3,068 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein biochemistry, Signal transduction] | [] | null | {'accessions': [Q80W83], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:d14e0b9764d2f5db795881bfc2843859 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
Organism: Oryctolagus cuniculus (Rabbit).
TaxID: 9986
Genes: Name=PPP2R5E;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme... | 843 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein biochemistry, Signal transduction] | [] | null | {'accessions': [Q28654], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': 'Nomenclature used in PubMed:8576224 refers to PP2A B subunit B\' delta isoform, which is cited as PP2A... |
uniprotkb_text_metadata_unified:5a03595d2b72a81a502a5849e9a6b884 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Ppp2r5c;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a parti... | 2,949 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics, Proteomics] | [] | null | {'accessions': [Q60996, O35708, Q6TQF7, Q99KW8, Q99N67, Q99N68], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=4; Name=2; Synonyms=Gamma-2; IsoId=Q60996-1; Sequence=Displayed; Name=1; Synonyms=Gamma-1; IsoId=Q60996-2; Sequence=VSP_014719... |
uniprotkb_text_metadata_unified:06fd6a38ab0e8cf72207e1ed0f67f7d5 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' eta isoform
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=B'ETA; OrderedLocusNames=At3g26020; ORFNames=MPE11.19;
## Function
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may als... | 1,794 | null | null | null | Plant Biology | true | false | [Plant defense, Brassinosteroid signaling pathway, Protein phosphatase, Cell biology, Molecular biology] | [] | null | {'accessions': [Q9LU89, B9DH07], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=1; Comment=A number of isoforms are produced. According to EST sequences.; Name=1; IsoId=Q9LU89-1; Sequence=Displayed;', 'BIOPHYSICOCHEMICAL PROPERTIES': NULL... |
uniprotkb_text_metadata_unified:b77d9eb41ecffb4ae3ae84614256f1fe | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A regulatory subunit sur-6 {ECO:0000305}
Organism: Caenorhabditis elegans.
TaxID: 6239
Genes: Name=sur-6 {ECO:0000312|WormBase:F26E4.1}; ORFNames=F26E4.1 {ECO:0000312|WormBase:F26E4.1};
## Function
Probable regulatory subunit of serine/threonine phosphatase let-92. Together with... | 2,279 | null | null | null | Molecular Biology | true | false | [Cell biology, Developmental biology, Genetics] | [] | null | {'accessions': [G5EDR3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': 'RNAi-med... |
uniprotkb_text_metadata_unified:237009b1325692eac800a6c0b735bb87 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine protein phosphatase 2A regulatory subunit B''beta
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=B''BETA; OrderedLocusNames=At5g28850; ORFNames=F7P1.30;
## Function
Regulatory subunit of type 2A protein phosphatase. Involved in post-transcriptional regulation of HMGR but n... | 692 | null | null | null | Molecular Biology | true | false | [Genetics, Protein biology, Cell biology] | [] | null | {'accessions': [Q5QIT3, Q56WJ0, Q940C6], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5QIT3-1; Sequence=Displayed; Name=2; IsoId=Q5QIT3-2; Sequence=VSP_046803;', 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': ... |
uniprotkb_text_metadata_unified:84401c8041c59ccc05ef142127439fed | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Probable serine/threonine protein phosphatase 2A regulatory subunit B''epsilon
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=B''EPSILON; OrderedLocusNames=At1g03960; ORFNames=F21M11.11;
## Function
Probable regulatory subunit of type 2A protein phosphatase. {ECO:0000250}.
## Keywords
Alt... | 587 | null | null | null | Molecular Biology | true | false | [Genetics, Proteomics, Cell biology] | [] | null | {'accessions': [Q84JI6, F4I2K5, Q9ZWB6], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q84JI6-1; Sequence=Displayed; Name=2; IsoId=Q84JI6-2; Sequence=VSP_046804;', 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': ... |
uniprotkb_text_metadata_unified:652f11f6d7263dba1097fe93ef1b0caf | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=PP2AB1; OrderedLocusNames=At1g51690; ORFNames=F19C24.10;
## Function
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may ... | 824 | null | null | null | Molecular Biology | true | false | [Genetics, Cell biology, Proteomics] | [] | null | {'accessions': [Q38821, Q0WL96, Q27GN0, Q8L842, Q9C8H8], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q38821-1; Sequence=Displayed; Name=2; IsoId=Q38821-2; Sequence=VSP_025610;', 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, '... |
uniprotkb_text_metadata_unified:e4748d8b58d8432d5291ed1d485c21f0 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
Organism: Oryctolagus cuniculus (Rabbit).
TaxID: 9986
Genes: Name=PPP2R2A;
## Function
Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved i... | 1,223 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics, Protein function] | [] | null | {'accessions': [P63150, P50409, Q00007], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENO... |
uniprotkb_text_metadata_unified:c24272e812219bc2f9fb11f2ac07d4a2 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein phosphatase PP2A regulatory subunit B
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
TaxID: 284812
Genes: Name=pab1; ORFNames=SPAC227.07c;
## Function
Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellula... | 1,394 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics, Proteomics] | [] | null | {'accessions': [Q12702, Q9UTD2], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:eab97608483196e152c10cc6d9ecb2e4 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Organism: Carassius auratus (Goldfish).
TaxID: 7957
Genes: Name=ppp2r2b;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to... | 879 | null | null | null | Biology | true | false | [Cell biology, Proteomics, Molecular Biology] | [] | null | {'accessions': [B6VA23], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:cb66e7e160f6310cbac2397d5fcd4ee7 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Organism: Homo sapiens (Human).
TaxID: 9606
Genes: Name=PPP2R2B;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a parti... | 2,348 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics, Neurobiology] | [] | null | {'accessions': [Q00005, A6NEJ2, A8K102, B3KPD0, B7Z2F2, B7Z304, D3DQF7, D3DQF8, G3V149], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=7; Name=1; Synonyms=Bbeta, Bbeta1; IsoId=Q00005-1; Sequence=Displayed; Name=2; Synonyms=Bbeta2; IsoId=... |
uniprotkb_text_metadata_unified:c417c55988d3dcc7c50d3e485e02b472 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Ppp2r2b;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a part... | 2,353 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics, Apoptosis, Mitochondrial biology] | [] | null | {'accessions': [Q6ZWR4, Q3UF60, Q8K413, Q9D3B7, Q9D6I1], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=Bbeta; IsoId=Q6ZWR4-1; Sequence=Displayed; Name=2; Synonyms=Bbeta2; IsoId=Q6ZWR4-2; Sequence=VSP_037983; Name=3; S... |
uniprotkb_text_metadata_unified:83f7911b3a3e718b46688fbdf0ee15e3 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Organism: Oryza sativa subsp. japonica (Rice).
TaxID: 39947
Genes: OrderedLocusNames=Os02g0224200, LOC_Os02g13110; ORFNames=OsJ_005772, P0470A03.14;
## Function
The B regulatory subunit may modulate substrate selectivity and catalytic a... | 692 | null | null | null | Molecular Biology | true | false | [Protein structure and function, Cell biology, Genetics] | [] | null | {'accessions': [Q0E2P1, A3A4Q0, B7ERB7, O82774, Q6Z8B7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, '... |
uniprotkb_text_metadata_unified:4ac440acc1c548d995984f9b0d00d33f | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Organism: Sus scrofa (Pig).
TaxID: 9823
Genes: Name=PPP2R2B;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particula... | 893 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics, Protein structure] | [] | null | {'accessions': [P54614], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:11e7fbb4bc8c53c56fa897168b34c363 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Organism: Danio rerio (Zebrafish) (Brachydanio rerio).
TaxID: 7955
Genes: Name=ppp2r2d; ORFNames=zgc:76887;
## Function
Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling m... | 1,286 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics] | [] | null | {'accessions': [Q6NY64], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:00f6ca37846d1b73df3766202c09c696 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Organism: Homo sapiens (Human).
TaxID: 9606
Genes: Name=PPP2R2D; Synonyms=KIAA1541;
## Function
Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. I... | 1,432 | null | null | null | Molecular Biology | true | false | [Cell biology, Proteomics, Genetics] | [] | null | {'accessions': [Q66LE6, A8KAK0, Q5SQJ2, Q9P1Y7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTI... |
uniprotkb_text_metadata_unified:64d98efdeb4aa3e863d7eba7b646ef2d | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
TaxID: 284812
Genes: Name=par1; Synonyms=pbp1; ORFNames=SPCC188.02;
## Function
The B regulatory subunit might modulate substrate selectivity and catalytic ... | 1,928 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics, Proteomics] | [] | null | {'accessions': [Q10428], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:e1e93ad741534e832a158fe562ecb441 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Suppressor of silencing 2b
Organism: Tobacco streak virus (strain WC) (TSV).
TaxID: 12318
Genes: ORFNames=ORF2b;
## Function
Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Ma... | 796 | null | null | null | Virology | true | false | [Virology, Molecular Biology, Cell biology, Immunology] | [] | null | {'accessions': [P89679], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:2fc2eadaf85e898ef9b2df5ec08849be | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Metalloendoproteinase 2-MMP {ECO:0000303|PubMed:10574937}
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=2MMP {ECO:0000303|PubMed:10574937}; Synonyms=MMP {ECO:0000312|EMBL:AEE35027.1}; OrderedLocusNames=At1g70170 {ECO:0000312|Araport:AT1G70170}; ORFNames=F20P5.11 {ECO:0000312|EMBL:AAB61099.... | 2,392 | null | null | null | Plant Biology | true | false | [Plant development, Proteolysis, Stress response, Cell biology] | [] | null | {'accessions': [O04529, Q0WVU1], 'cc_topics': {'ACTIVITY REGULATION': 'Repressed by acetohydroxamic acid (AHA). {ECO:0000269|PubMed:24156403}.', 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'pH dependence: Optimum pH is 7-8. {ECO:0000269|PubMed:24156403}; Temperature dependence: Opti... |
uniprotkb_text_metadata_unified:9da0a6af587a943b3743a7921de7c687 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Napin-like polypeptide
Organism: Brassica oleracea var. alboglabra (Chinese kale) (Brassica alboglabra).
TaxID: 3714
## Function
Inhibits cell-free protein synthesis. Inhibits trypsin and chymotrypsin. Does not inhibit ribonuclease of protease activity. Has antibacterial activity against Gram-negative bacterium P.fl... | 1,195 | null | null | null | Biology | true | false | [Proteomics, Molecular Biology, Cell biology, Microbiology] | [] | null | {'accessions': [P84782], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:bc00fcb0f3a546999001b577735b9a68 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 2S seed storage albumin protein {ECO:0000305}
Organism: Fagopyrum tataricum (Tartarian buckwheat) (Polygonum tataricum).
TaxID: 62330
## Function
Seed storage protein. {ECO:0000305}.
## Tissue Specificity
Expressed in seeds (at protein level) (PubMed:21645012, PubMed:29306152). Expressed in seeds (PubMed:29306152).... | 635 | null | null | null | Biology | true | false | [Plant biology, Proteomics, Molecular biology] | [] | null | {'accessions': [E9NX73], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': 'Causes an allergic reaction in human. Binds to IgE of patients allergic to buckwheat (PubMed:21645012, PubMed:29306152, PubMed:33412487). Binds to IgE in 74% of the 23 tartarian buckwheat- allergic patients tested (PubMed:29306152). IgE-bi... |
uniprotkb_text_metadata_unified:2161c50f028b140935e97f9187f8876e | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 300-1L
Organism: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
TaxID: 561444
Genes: OrderedLocusNames=War-025;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. {ECO:0000250}.
## Subcellular Location
Host membran... | 537 | null | null | null | Virology | true | false | [Virology, Cell biology, Molecular biology] | [] | null | {'accessions': [P0C9K4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:d646249c52cabe43eea5619dada44aeb | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Spermatogenesis-associated protein 31F1B {ECO:0000305}
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Spata31f1b {ECO:0000312|MGI:MGI:3701946}; Synonyms=Fam205a2 {ECO:0000312|MGI:MGI:3701946}, Gm13298 {ECO:0000312|MGI:MGI:3701946}, Spata31f1-2 {ECO:0000305};
## Subcellular Location
Membrane {ECO:0000255}; ... | 500 | null | null | null | Molecular Biology | true | false | [Cell biology, Genetics] | [] | null | {'accessions': [C0HKD1, A2APU8], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': N... |
uniprotkb_text_metadata_unified:1970e83c7f61cce855bfd7f8ce9df599 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # DRBM domain-containing protein 340R
Organism: Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
TaxID: 176652
Genes: ORFNames=IIV6-340R;
## Keywords
Reference proteome, RNA-binding.
## GO
GO; GO:0016442; C:RISC complex; IEA:TreeGrafter.
GO; GO:0070578; C:RISC-loading complex; IEA:TreeGrafter.
GO; GO... | 558 | null | null | null | Molecular Biology | true | false | [Genetics, Virology, RNA biology] | [] | null | {'accessions': [Q91FI4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:da714c1b505fc8afe908e6fc524b958a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Salivary protein SG34 {ECO:0000305}
Organism: Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
TaxID: 7159
Genes: ORFNames=AAEL003600 {ECO:0000303|PubMed:31265906};
## Function
(Microbial infection) Enhances replication of dengue virus type 2 in human keratinocytes, probably by suppressing the production of typ... | 671 | null | null | null | Biology | true | false | [Molecular Biology, Immunology, Cell biology] | [] | null | {'accessions': [A0A1S4F550, Q17F12, Q1HRF7, Q1HRW0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISR... |
uniprotkb_text_metadata_unified:5750f04d2c57a7c3cda3ae0c556aeaea | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 360-11L
Organism: African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV).
TaxID: 561443
Genes: OrderedLocusNames=Pret-033;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. In addition, inhibits the phosphorylat... | 1,241 | null | null | null | Virology | true | false | [Immunology, Virology, Cell biology] | [] | null | {'accessions': [P0C9P8], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:698047ba6215bd623f5157090747922a | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 360-14L
Organism: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV).
TaxID: 561445
Genes: OrderedLocusNames=Ken-038;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. Also inhibits the host cGAS/STING-mediated type I interfe... | 992 | null | null | null | Virology | true | false | [Virology, Immunology, Cell biology] | [] | null | {'accessions': [P0C9Q6], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:cb5ecaf457c0c8715d3e454a7ba85147 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 360-14L
Organism: African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) (ASFV).
TaxID: 561443
Genes: OrderedLocusNames=Pret-037;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. Also inhibits the host cGAS/STING-medi... | 1,011 | null | null | null | Virology | true | false | [Virology, Immunology, Cell biology] | [] | null | {'accessions': [P0C9Q7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:5feacadb33770fa40e8511c375991925 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Protein MGF 360-14L
Organism: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
TaxID: 561444
Genes: OrderedLocusNames=War-035;
## Function
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages. Also inhibits the host cGAS/STING-mediated type I i... | 983 | null | null | null | Virology | true | false | [Virology, Immunology, Cell biology] | [] | null | {'accessions': [P0C9Q5], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:5aeeb897ca47983976cd601c178da12b | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Coumaroyl-CoA:anthocyanidin 3-O-glucoside-6''-O-coumaroyltransferase 2
Organism: Arabidopsis thaliana (Mouse-ear cress).
TaxID: 3702
Genes: Name=3AT2; OrderedLocusNames=At1g03495; ORFNames=F21B7.12;
## Function
Involved in the acylation of the 6'' position of the 3-O- glucose residue of anthocyanin. Also able to use... | 744 | null | null | null | Plant Biology | true | false | [Plant biochemistry, Plant genetics, Plant molecular biology] | [] | null | {'accessions': [Q9LR73], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: KM=6.6 uM for p-coumaroyl-CoA (with cyanidin 3,5-diglucoside as cosubstrate) {ECO:0000269|PubMed:17425720}; KM=9.4 uM for feruloyl-CoA (with cyanidin ... |
uniprotkb_text_metadata_unified:b84b774f103a3789a3502ade4f905aff | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Anthocyanidin 3-O-glucoside 6''-O-acyltransferase
Organism: Perilla frutescens (Beefsteak mint) (Perilla ocymoides).
TaxID: 48386
## Function
Catalyzes the transfer of the p-coumaric and caffeic acids from their CoA esters to the 3-glucosyl moiety of a range of anthocyanidin 3-O-glucosides, 3,5-di-O-glucosides and c... | 1,380 | null | null | null | Biology | true | false | [Plant biology, Biochemistry, Enzymology] | [] | null | {'accessions': [Q9MBC1], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=an anthocyanidin 3-O-beta-D-glucoside + (E)-4-coumaroyl-CoA = an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-b... |
uniprotkb_text_metadata_unified:5b3ca6d58d94f70729787c867bb533d2 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 3-beta-hydroxysteroid dehydrogenase {ECO:0000303|PubMed:36933555}
Organism: Klebsiella aerogenes (Enterobacter aerogenes).
TaxID: 548
Genes: ORFNames=NUT96_16600 {ECO:0000312|EMBL:UUX43973.1};
## Function
Catalyzes the degradation of estradiol into estrone (PubMed:36933555). Can also degrade testosterone (PubMed:369... | 813 | null | null | null | Biochemistry | true | false | [Enzymology, Metabolism, Molecular Biology] | [] | null | {'accessions': [P0DX23], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=testosterone + NADP(+) = androst-4-ene-3,17-dione + NADPH + H(+); Xref=Rhea:RHEA:14981, ChEBI:CHEBI:15378, ChE... |
uniprotkb_text_metadata_unified:82fb2ba5cb62ee2f63b6f2a825843efd | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
Organism: Homo sapiens (Human).
TaxID: 9606
Genes: Name=HSD3B1 {ECO:0000312|HGNC:HGNC:5217}; Synonyms=3BH, HSDB3A;
## Function
A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo- ... | 3,758 | null | null | null | Biochemistry | true | false | [Enzymology, Steroid metabolism, Protein structure, Cell biology] | [] | null | {'accessions': [P14060, A8K691, Q14545, Q8IV65], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: KM=0.13 uM for dehydroepiandrosterone (in the presence of NAD(+)) {ECO:0000269|PubMed:1401999}; KM=0.33 uM for pregnenolone (i... |
uniprotkb_text_metadata_unified:a0cf75bd5536c958abbb1995081ee9cc | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # NADPH-dependent 3-keto-steroid reductase Hsd3b5 {ECO:0000305|PubMed:7491113}
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Hsd3b5 {ECO:0000312|MGI:MGI:104645};
## Function
Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestostero... | 2,728 | null | null | null | Biochemistry | true | false | [Enzymology, Steroid metabolism, Cell biology] | [] | null | {'accessions': [Q61694, Q91X27], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: KM=0.47 uM for dihydrotestosterone {ECO:0000269|PubMed:7491113};', 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=5alpha-androstane-3b... |
uniprotkb_text_metadata_unified:d11892a1d3d68ba438d6b18c4dcd49c2 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 3 beta-hydroxysteroid dehydrogenase type 7 {ECO:0000305}
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Hsd3b7 {ECO:0000312|MGI:MGI:2141879};
## Function
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydr... | 2,517 | null | null | null | Biochemistry | true | false | [Enzymology, Lipid metabolism, Steroid biosynthesis, Cell biology] | [] | null | {'accessions': [Q9EQC1, A2RTR5], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=(24S)-7alpha-dihydroxycholesterol + NAD(+) = (24S)-7alpha,24- dihydroxycholest-4-en-3-one + NADH + H(+... |
uniprotkb_text_metadata_unified:64aa0e0542606e0e004ae7a5c7f04700 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)).
TaxID: 10254
Genes: Name=OPG174; OrderedLocusNames=VACWR170; ORFNames=SALF7L;
## Function
Catalyzes the oxidative conversion of Delta(5)-ene-3-beta- hydroxy steroid, and th... | 1,265 | null | null | null | Virology | true | false | [Molecular Biology, Virology, Biochemistry] | [] | null | {'accessions': [P26670, Q76ZN3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=a 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid; Xref=Rhea:RHEA:14709, ChEBI:CHEBI:47907, ChEBI:CH... |
uniprotkb_text_metadata_unified:4adb1522f65928483214cbb1326ecbbf | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # SH3 domain-binding protein 1
Organism: Rattus norvegicus (Rat).
TaxID: 10116
Genes: Name=Sh3bp1 {ECO:0000312|RGD:1306275};
## Function
GTPase activating protein/GAP which specifically converts GTP-bound Rho-type GTPases including RAC1 and CDC42 in their inactive GDP-bound form. By specifically inactivating RAC1 at t... | 3,814 | null | null | null | Cell Biology | true | false | [Cell biology, Molecular biology, Protein function, Cell migration, Actin cytoskeleton, Phagocytosis, Cell junctions, Angiogenesis, Signal transduction] | [] | null | {'accessions': [D3ZFJ3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:446e0c294fc1af2f29cc842851c3c225 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # SH3 domain-binding protein 5
Organism: Mus musculus (Mouse).
TaxID: 10090
Genes: Name=Sh3bp5; Synonyms=Sab {ECO:0000303|PubMed:10339589};
## Function
Functions as a guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (By similarity). Inhibits the auto- and transphosphorylation activity of ... | 1,609 | null | null | null | Molecular Biology | true | false | [Cell biology, Protein biochemistry, Signal transduction] | [] | null | {'accessions': [Q9Z131, Q3TTD6, Q8C903, Q8VCZ0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': 'Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9Z131-1; Sequence=Displayed; Name=2; IsoId=Q9Z131-2; Sequence=VSP_010882; Name=3; IsoId=Q9Z131-3; Sequence=VSP_022572, VSP_0... |
uniprotkb_text_metadata_unified:415eb2a7901fa948953073bd72a4e0a9 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # (+)-3-carene synthase 1, chloroplastic {ECO:0000303|PubMed:21323772, ECO:0000303|PubMed:21385377}
Organism: Picea sitchensis (Sitka spruce) (Pinus sitchensis).
TaxID: 3332
Genes: Name=TPS-3car1 {ECO:0000303|PubMed:21323772, ECO:0000303|PubMed:21385377};
## Function
Terpene synthase (TPS) involved in the biosynthesis... | 1,797 | null | null | null | Biology | true | false | [Plant biology, Biochemistry, Molecular biology, Plant defense mechanisms] | [] | null | {'accessions': [F1CKI6, C0PSU3, F1CKI7], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: KM=6.88 uM for geranyl diphosphate {ECO:0000269|PubMed:21323772}; Vmax=32.1 pmol/sec/ug enzyme with geranyl diphosphate as substrate {... |
uniprotkb_text_metadata_unified:7c36b7515de34e3ab789ad5c0056a427 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # (+)-3-carene synthase 1, chloroplastic {ECO:0000303|PubMed:21385377}
Organism: Picea engelmannii x Picea glauca (Hybrid white spruce).
TaxID: 373101
Genes: Name=TPS-3car1 {ECO:0000303|PubMed:21385377};
## Function
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer... | 1,491 | null | null | null | Biology | true | false | [Plant biology, Biochemistry, Molecular biology] | [] | null | {'accessions': [F2XF94], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=(2E)-geranyl diphosphate = (+)-car-3-ene + diphosphate; Xref=Rhea:RHEA:32539, ChEBI:CHEBI:7, ChEBI:CHEBI:33019... |
uniprotkb_text_metadata_unified:04b448be9389840439dfc4f4ac97ceab | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Carene synthase 3, chloroplastic
Organism: Picea sitchensis (Sitka spruce) (Pinus sitchensis).
TaxID: 3332
Genes: Name=TPS-3car3;
## Function
Terpene synthase (TPS) involved in defensive oleoresin formation in conifers in response to insect attack or other injury. {ECO:0000269|PubMed:21323772}.
## Subcellular Locat... | 1,086 | null | null | null | Biology | true | false | [Plant biology, Biochemistry, Molecular biology] | [] | null | {'accessions': [F1CKI9, F1CKJ0], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': 'Kinetic parameters: Note=kcat is less than 0.00001 sec(-1) with geranyl diphosphate as substrate. {ECO:0000269|PubMed:21323772};', 'BIOTECHNOLOGY': NULL, 'CATALYT... |
uniprotkb_text_metadata_unified:ab4e50e92c34a3b219f57007c79700ac | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Tricyclic peptide MS-271 {ECO:0000303|PubMed:8689231, ECO:0000303|PubMed:8689232}
Organism: Streptomyces sp.
TaxID: 1931
## Function
Inhibits chicken myosin light chain kinase with an IC(50) of 8 M. Does not inhibit bovine cAMP-dependent protein kinase or rat protein kinase C. Antibacterial activity against the Gram... | 970 | null | null | null | Microbiology | true | false | [Microbiology, Biochemistry, Molecular Biology] | [] | null | {'accessions': [P85078], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': NULL, 'CAUTION': NULL, 'COFACTOR': NULL, 'DEVELOPMENTAL STAGE': NULL, 'DISEASE': NULL, 'DISRUPTION PHENOTYPE': NULL, 'DO... |
uniprotkb_text_metadata_unified:a178c7de9a37be21f6517516f2124ec6 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Catabolic 3-dehydroquinase 2 {ECO:0000255|HAMAP-Rule:MF_03136}
Organism: Aspergillus terreus (strain NIH 2624 / FGSC A1156).
TaxID: 341663
Genes: Name=qutE2 {ECO:0000255|HAMAP-Rule:MF_03136}; ORFNames=ATEG_07673.2;
## Function
Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon sour... | 1,047 | null | null | null | Biochemistry | true | false | [Enzymology, Metabolism, Microbiology] | [] | null | {'accessions': [P0CI63, Q0CF61], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=3-dehydroquinate = 3-dehydroshikimate + H2O; Xref=Rhea:RHEA:21096, ChEBI:CHEBI:15377, ChEBI:CHEBI:1663... |
uniprotkb_text_metadata_unified:3027f32243256a4b27d4a420285e5347 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Catabolic 3-dehydroquinase {ECO:0000255|HAMAP-Rule:MF_03136}
Organism: Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
TaxID: 284592
Genes: Name=DQD1 {ECO:0000255|HAMAP-Rule:MF_03136}; OrderedLocusNames=DEHA2F23584g;
## Function
Is in... | 1,152 | null | null | null | Biochemistry | true | false | [Enzymology, Metabolism, Microbiology] | [] | null | {'accessions': [Q6BKA3], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=3-dehydroquinate = 3-dehydroshikimate + H2O; Xref=Rhea:RHEA:21096, ChEBI:CHEBI:15377, ChEBI:CHEBI:16630, ChEBI... |
uniprotkb_text_metadata_unified:99fc2db0f7304c4c5073c062579764f7 | non_pmc_labels | uniprotkb_text_metadata_unified.parquet | null | null | null | null | # Catabolic 3-dehydroquinase {ECO:0000255|HAMAP-Rule:MF_03136}
Organism: Neurospora africana.
TaxID: 5143
Genes: Name=qa-2 {ECO:0000255|HAMAP-Rule:MF_03136};
## Function
Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway. {ECO:0000255|HAMAP-Rul... | 988 | null | null | null | Biochemistry | true | false | [Enzymology, Metabolism, Molecular biology] | [] | null | {'accessions': [Q58HK4], 'cc_topics': {'ACTIVITY REGULATION': NULL, 'ALLERGEN': NULL, 'ALTERNATIVE PRODUCTS': NULL, 'BIOPHYSICOCHEMICAL PROPERTIES': NULL, 'BIOTECHNOLOGY': NULL, 'CATALYTIC ACTIVITY': 'Reaction=3-dehydroquinate = 3-dehydroshikimate + H2O; Xref=Rhea:RHEA:21096, ChEBI:CHEBI:15377, ChEBI:CHEBI:16630, ChEBI... |
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