{"paperId": "a0670e49b888b0b6671a843215eb76dcc7f93919", "title": "Solar and wind power data from the Chinese State Grid Renewable Energy Generation Forecasting Competition", "abstract": "Accurate solar and wind generation forecasting along with high renewable energy penetration in power grids throughout the world are crucial to the days-ahead power scheduling of energy systems. It is difficult to precisely forecast on-site power generation due to the intermittency and fluctuation characteristics of solar and wind energy. Solar and wind generation data from on-site sources are beneficial for the development of data-driven forecasting models. In this paper, an open dataset consisting of data collected from on-site renewable energy stations, including six wind farms and eight solar stations in China, is provided. Over two years (2019–2020), power generation and weather-related data were collected at 15-minute intervals. The dataset was used in the Renewable Energy Generation Forecasting Competition hosted by the Chinese State Grid in 2021. The process of data collection, data processing, and potential applications are described. The use of this dataset is promising for the development of data-driven forecasting models for renewable energy generation and the optimization of electricity demand response (DR) programs for the power grid. Measurement(s) renewable energy generation Technology Type(s) supervisory control and data acquisition system Sample Characteristic - Location China", "year": 2022, "publicationDate": "2022-09-21", "publicationTypes": ["JournalArticle"], "venue": "Scientific Data", "journal": {"name": "Scientific Data", "volume": "9"}, "citationCount": 184, "referenceCount": 20, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s41597-022-01696-6.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2108962596", "name": "Yongbao Chen"}, {"authorId": "2150637946", "name": "Junjie Xu"}], "url": "https://www.semanticscholar.org/paper/a0670e49b888b0b6671a843215eb76dcc7f93919", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "7298d5245d355729fb759489ba13481e7b5756bb", "title": "Comparative techno-economic analysis of various stand-alone and grid connected (solar/wind/fuel cell) renewable energy systems", "abstract": null, "year": 2023, "publicationDate": "2023-06-01", "publicationTypes": ["JournalArticle"], "venue": "International journal of hydrogen energy", "journal": {"name": "International Journal of Hydrogen Energy"}, "citationCount": 83, "referenceCount": 81, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2222186269", "name": "Mansoor Urf Manoo"}, {"authorId": "66544938", "name": "Faheemullah Shaikh"}, {"authorId": "120092394", "name": "Laveet Kumar"}, {"authorId": "93956260", "name": "M. Arıcı"}], "url": "https://www.semanticscholar.org/paper/7298d5245d355729fb759489ba13481e7b5756bb", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "47930b9394fcae5bf26c9ff19fb441f5dc63247f", "title": "Energy Trading Interface for Grid-Tied Wind-Solar Power Generation System", "abstract": "Surging clean energy demand clashes with grid stability concerns, calling for creative solutions. This work explores the synergy between peer-to-peer (P2P) energy trading and grid-connected wind-solar systems. It is apparent that, in the contemporary grid scenario, renewable power injection involving integrated wind-solar power generation is proliferating, and hence grid stability and excess energy utilization become critical challenges. P2P trading emerges as a promising remedy, allowing prosumers (consumers who also produce) to directly exchange surplus energy, fostering a more decentralized and efficient energy system. Leveraging MATLAB simulations, the project assesses the technical feasibility of such systems. It then designs and implements a P2P energy transfer system with a user-friendly dashboard, empowering prosumers to actively participate and optimize their energy usage. By analyzing benefits for both prosumers and the grid, the project showcases the significant potential of P2P trading in paving the way for a sustainable and equitable energy future.", "year": 2024, "publicationDate": "2024-08-02", "publicationTypes": ["Conference"], "venue": "2024 Control Instrumentation System Conference (CISCON)", "journal": {"name": "2024 Control Instrumentation System Conference (CISCON)", "pages": "1-6"}, "citationCount": 9, "referenceCount": 29, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2056800832", "name": "Nitin Patil"}, {"authorId": "2323893957", "name": "Yeetendra Dubey"}, {"authorId": "2323897154", "name": "M. Himani"}, {"authorId": "9311698", "name": "J. Ramprabhakar"}, {"authorId": "2323831196", "name": "A. R."}, {"authorId": "143887511", "name": "V. Meena"}], "url": "https://www.semanticscholar.org/paper/47930b9394fcae5bf26c9ff19fb441f5dc63247f", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "86358b4947d1fcdceda5b079c92fce56f72a887d", "title": "Advances and development of wind–solar hybrid renewable energy technologies for energy transition and sustainable future in India", "abstract": "While solar power projects are built on a continuous ground, wind power projects require scattered land, raising transmission costs and increasing the risk of land-related complications. Wind–solar hybrid (WSH) projects have been proposed to address these issues and accelerate installation. WSH power projects will create a well-defined area with sufficient infrastructure, including evacuation facilities, where the project’s risks can be reduced. The extensive coastline of India is endowed with high wind flow speed and plentiful solar power resources, creating an ideal environment for WSH projects to prosper while simultaneously improving grid stability and reliability. WSH plants guarantee higher transmission efficiency and cost-effectiveness than their stand-alone counterparts. As of 30.11.2021, 3.75 GW of WSH projects have been granted, with 0.148 GW of operational capacity and 1.7 GW of WSH projects in various bidding phases. In this paper, we discussed state-wise WSH potential, the key players in the WSH project, the National WSH, and the State WSH policy and amendments. Also, the WSH project’s physical progress and commercial details are covered. A feasibility study of the WSH plant is performed, and the primary design strategy for deploying WSH power facilities in India is discussed. It covers every step of this process, from design technique to choosing and evaluating potential locations for such hybrid projects, optimally placing wind turbines and solar panels, overall capacity mix for hybrid plants, and ultimately power evacuation optimization. Additionally, a brief study of the savings from these hybrid plants and the environmental, social, and governance standards which are necessary to implement these projects are provided. The potential challenges connected with WSH technologies are examined in depth, and potential solutions and mitigations for the challenges are provided. Designing a WSH for small-scale irrigation is provided along with the size and choice of wind and solar systems. Degradation of PV systems and carbon savings are included, along with some policy measures to boost the proportion of WSH in the entire power mix. In India, the development of large-scale WSH projects is still in its early stages, and more research is required to explore technical, commercial, and policy elements that influence project design. The policy suggestions for improvement of the WSH project are provided. The WSH project developers, potential investors, stakeholders, innovators, policymakers, manufacturers, designers, and researchers will benefit from the recommendations based on the review’s findings.", "year": 2023, "publicationDate": "2023-01-29", "publicationTypes": ["JournalArticle", "Review"], "venue": "Energy & Environment", "journal": {"name": "Energy & Environment", "pages": "2517 - 2565", "volume": "35"}, "citationCount": 22, "referenceCount": 140, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2286294025", "name": "J. Charles"}, {"authorId": "2359130451", "name": "Rajesh S Kumar"}, {"authorId": "151123585", "name": "M. Majid"}], "url": "https://www.semanticscholar.org/paper/86358b4947d1fcdceda5b079c92fce56f72a887d", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "3a07972cb00d6da5c8641cee5e0266d86ee031ca", "title": "Machine learning and the renewable energy revolution: Exploring solar and wind energy solutions for a sustainable future including innovations in energy storage", "abstract": "This article evaluates the present global condition of solar and wind energy adoption and explores their benefits and limitations in meeting energy needs. It examines the historical and evolutionary growth of solar and wind energy, global trends in the usage of renewable energy, and upcoming technologies, including floating solar and vertical‐axis wind turbines. The importance of smart grid technology and energy storage alternatives for enhancing the effectiveness and dependability of renewable energy is explored. In addition, the role of Electric Vehicles (EVs) in a modern smart grid has been assessed. Furthermore, the economic benefits, and most recent technological developments of solar and wind energy and their environmental and social ramifications. The potential of solar and wind energy to meet the increasing global energy demand and the problems and opportunities facing the renewable energy industry have shown excellent promise. Machine learning applications for solar and wind energy generation are vital for sustainable energy production. Machine learning can help in design, optimization, cost reduction, and, most importantly, in improving the efficacy of solar and wind energy, including advancing energy storage. This assessment is a crucial resource for policymakers, industry leaders, and researchers who aim to make the world cleaner and more sustainable. Ultimately, this review has shown the great potential of solar and wind energy in meeting global energy demands and sustainable goals.", "year": 2024, "publicationDate": "2024-01-08", "publicationTypes": ["JournalArticle", "Review"], "venue": "Sustainable Development", "journal": {"name": "Sustainable Development"}, "citationCount": 208, "referenceCount": 132, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/sd.2885", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2266586240", "name": "Abu Danish Aiman Bin Abu Sofian"}, {"authorId": "2110551401", "name": "Hooi Ren Lim"}, {"authorId": "2042771641", "name": "Heli Siti Halimatul Munawaroh"}, {"authorId": "2238135665", "name": "Zengling Ma"}, {"authorId": "27349248", "name": "K. Chew"}, {"authorId": "8813642", "name": "P. Show"}], "url": "https://www.semanticscholar.org/paper/3a07972cb00d6da5c8641cee5e0266d86ee031ca", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "4a323972efe4826713f4386b0d53eea59d03813f", "title": "Mitigating Uncertainty Problems of Renewable Energy Resources Through Efficient Integration of Hybrid Solar PV/Wind Systems Into Power Networks", "abstract": "In recent years, there has been a proliferation of studies focusing on sustainable energy sources aimed at delivering reliable power with reduced greenhouse gas emissions. Among these endeavors, electrification of urban areas through incorporation of renewable energy sources (RESs) stands out as a pivotal application of RES. Increasingly, the integration of RESs like PV and wind into the power grid is being pursued as an alternative to traditional centralized power stations, offering a means to ensure continuous power supply during peak demand periods while simultaneously managing unit costs, thereby providing a systematic and readily accessible power supply to consumers. This paper presents a comprehensive examination of hybrid wind and PV with focus on achieving consistent DC bus-bar voltage through integration with microcontroller system via buck-boost converter. Additionally, hybrid system’s output voltage is tailored to accommodate necessary battery connections. However, given influence of environmental variables like fluctuations in solar irradiation and wind velocity on power output of PV and wind seamless integration of these sources becomes paramount. To address this challenge MATLAB model is developed to simulate grid integration of hybrid wind and PV, enabling a detailed analysis of integrated grid’s performance. Simulation results are then proposed with those obtained from conventional fossil fuel-based power generation methods. In this research underscores importance of integrating RES into existing power grids and highlights efficacy of hybrid wind and PV in meeting this objective. Findings presented herein contribute to advancing discourse on sustainable energy solutions, offering valuable insights for policymakers, industry stakeholders, and researchers.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "IEEE Access", "journal": {"name": "IEEE Access", "pages": "30311-30328", "volume": "12"}, "citationCount": 135, "referenceCount": 118, "influentialCitationCount": 8, "isOpenAccess": true, "openAccessPdfUrl": "https://ieeexplore.ieee.org/ielx7/6287639/6514899/10445249.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2299938607", "name": "M. Ahmed"}, {"authorId": "32794408", "name": "S. Mirsaeidi"}, {"authorId": "2006361672", "name": "M. A. Koondhar"}, {"authorId": "2288591842", "name": "Nabil Karami"}, {"authorId": "2221303828", "name": "E. Tag-Eldin"}, {"authorId": "143815566", "name": "Nivin A. Ghamry"}, {"authorId": "1402333322", "name": "R. El-Sehiemy"}, {"authorId": "30957432", "name": "Z. Alaas"}, {"authorId": "2351996466", "name": "Ibrahim Mahariq"}, {"authorId": "2330530698", "name": "A. M. Sharaf"}], "url": "https://www.semanticscholar.org/paper/4a323972efe4826713f4386b0d53eea59d03813f", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "6439fddc17bf8a8ac9a2dbd2eac8d546b7a7809f", "title": "Research on key technologies of large-scale wind-solar hybrid grid energy storage capacity big data configuration optimization", "abstract": "Due to the uncertainty and randomness of large-scale wind and light, the output power of the power grid has great fluctuations. If it is directly connected to the grid, it will affect the main grid. In addition, when the grid switches between on-grid/off-grid operation modes, there will be power shortages, shocks and oscillations. The scientific and reasonable configuration of energy storage system capacity big data can reduce the load power shortage rate, improve the utilization rate of renewable energy, and ensure the reliable operation of the power grid. For this reason, the key technology of large-scale wind-solar hybrid grid energy storage capacity big data configuration optimization is studied. A large-scale wind-solar hybrid grid energy storage structure is proposed, and the working characteristics of photovoltaic power generation and wind power generation are analyzed, and the probability model of photovoltaic power generation, wind power generation and load, as well as the charging and discharging model of battery and super capacitor are established accordingly. On this basis, the optimization objective function is set, the constraints are determined, and the large-scale wind-solar hybrid grid energy storage capacity big data configuration optimization model is constructed. And the PSO algorithm is used to solve the model to realize the big data configuration optimization of large-scale wind-solar hybrid grid energy storage capacity. The research results show that the proposed method of large-scale wind-solar hybrid grid energy storage system has good power supply reliability and economy, and can effectively improve the utilization rate of renewable energy.", "year": 2023, "publicationDate": "2023-08-21", "publicationTypes": ["JournalArticle"], "venue": "Wind Engineering : The International Journal of Wind Power", "journal": {"name": "Wind Engineering", "pages": "32 - 43", "volume": "48"}, "citationCount": 8, "referenceCount": 14, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2068198710", "name": "X. Tong"}], "url": "https://www.semanticscholar.org/paper/6439fddc17bf8a8ac9a2dbd2eac8d546b7a7809f", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "cb5ac403f6ed0934cd01c51a2c9f7f0d5ae458ea", "title": "Optimizing wind/solar combinations at finer scales to mitigate renewable energy variability in China", "abstract": "Abstract China has set ambitious goals to cap its carbon emissions and increase low-carbon energy sources to 20% by 2030 or earlier. However, wind and solar energy production can be highly variable: the stability of single wind/solar and hybrid wind-solar energy and the effects of wind/solar ratio and spatial aggregation on energy stability remain largely unknown in China, especially at the grid cell scale. To address these issues, we analyzed the newly 2007–2014 hourly wind and solar data, which have higher resolution and quality than those used in previous research. The stability of single wind/solar energy production clearly increased as the wind/solar energy capacity factor increased, and there were significant functional relationships between single wind/solar energy stability and the wind/solar energy capacity factor. Highly stable wind energy was concentrated in eastern Inner Mongolia, northeastern China, and northern China while highly stable solar energy was concentrated in the Tibetan Plateau, Inner Mongolia, and northwestern China. Different wind/solar ratios affected the stability of hybrid wind-solar energy through a unimodal relationship, allowing us to produce a map of optimal wind/solar ratios throughout China in order to minimize the variability of hybrid wind-solar energy production. At the optimal wind/solar ratio, the most stable hybrid wind-solar energy was concentrated in eastern Inner Mongolia, northeastern China, and northern China. The variability of single and hybrid wind/solar energy decreased as the aggregated area size increased, especially for wind-dominated energy systems. These results have important practical applications: (a) using the optimal wind/solar ratio to install simple hybrid wind-solar energy systems locally; (b) prioritizing the deployment of large-scale wind farms or centralized solar photovoltaic stations in regions with high hybrid energy stability; and (c) strongly promoting regional cooperation, such as breaking inter-provincial power grid barriers, to reduce the variability of hybrid wind-solar energy production and thus operational costs.", "year": 2020, "publicationDate": "2020-10-01", "publicationTypes": [], "venue": null, "journal": {"name": "Renewable & Sustainable Energy Reviews", "pages": "110151", "volume": "132"}, "citationCount": 197, "referenceCount": 47, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S1364032120304421/pdf", "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2116204700", "name": "Laibao Liu"}, {"authorId": "2116204700", "name": "Laibao Liu"}, {"authorId": "2116204700", "name": "Laibao Liu"}, {"authorId": "19304355", "name": "Z. Wang"}, {"authorId": "2153676078", "name": "Yang Wang"}, {"authorId": "2152809919", "name": "Jun Wang"}, {"authorId": "2112567216", "name": "Rui Chang"}, {"authorId": "49430802", "name": "Gang He"}, {"authorId": "46479980", "name": "Wenjun Tang"}, {"authorId": "2111125939", "name": "Ziqi Gao"}, {"authorId": "2118505036", "name": "Jiangtao Li"}, {"authorId": "2388628923", "name": "Changyi Liu"}, {"authorId": "2111641996", "name": "Lin Zhao"}, {"authorId": "93773116", "name": "D. Qin"}, {"authorId": "8086867", "name": "Shuangcheng Li"}], "url": "https://www.semanticscholar.org/paper/cb5ac403f6ed0934cd01c51a2c9f7f0d5ae458ea", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "0f7008ef83636634f6ab9a50db0b6c2e5733f4df", "title": "Optimization of hybrid grid-tie wind solar power system for large-scale energy supply in Cameroon", "abstract": null, "year": 2022, "publicationDate": "2022-11-15", "publicationTypes": [], "venue": "International Journal of Energy and Environmental Engineering", "journal": {"name": "International Journal of Energy and Environmental Engineering", "pages": "777-789", "volume": "14"}, "citationCount": 18, "referenceCount": 42, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2132732537", "name": "Kitmo"}, {"authorId": "100958992", "name": "G. B. Tchaya"}, {"authorId": "92633936", "name": "N. Djongyang"}, {"authorId": "2277282920", "name": "on behalf of all the authors"}], "url": "https://www.semanticscholar.org/paper/0f7008ef83636634f6ab9a50db0b6c2e5733f4df", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "ff0d5ec6a24e6acae3179ef3c6283e9089fd4fdc", "title": "Optimized Grid-Connected Hybrid Renewable Energy Power Generation: A Comprehensive Analysis of Photovoltaic, Wind, and Fuel Cell Systems", "abstract": "This paper provides a comprehensive analysis of a grid-connected hybrid microgrid system that seamlessly integrates renewable energy sources, encompassing wind generators, solar arrays, and Fuel Cells (FCs). Emphasis is placed on the pivotal role of power electronic converters in optimizing control and energy management strategies for these diverse sources. The wind and solar subsystems employ Perturb and Observe (P&O) controllers to achieve Maximum Power Point Tracking (MPPT). Additionally, the study delves into the analysis and control design of the grid-connected hybrid system inverter, employing a Proportional-Integral (PI) control technique in the synchronous d-q frame to maximize the output voltage response and active power. In managing renewable grid energy based on artificial neural networks (ANNs), the main goal is to address grid availability concerns by prioritizing renewable sources. The hybrid system acts as a backup during grid unavailability and simultaneously produces hydrogen via electrolysis. The excess energy is seamlessly supplied to the grid upon filling the hydrogen tank. The proposed solution shows great promise for use in renewable energy management systems that combine hybrid technologies.", "year": 2024, "publicationDate": "2024-06-01", "publicationTypes": ["JournalArticle"], "venue": "Engineering, Technology & Applied Science Research", "journal": {"name": "Engineering, Technology & Applied Science Research"}, "citationCount": 15, "referenceCount": 33, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.48084/etasr.6936", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2283158039", "name": "Mohamed A. J. Al-Ani"}, {"authorId": "13319856", "name": "M. A. Zdiri"}, {"authorId": "9222360", "name": "Fatma Ben Salem"}, {"authorId": "2249314089", "name": "Nabil Derbel"}], "url": "https://www.semanticscholar.org/paper/ff0d5ec6a24e6acae3179ef3c6283e9089fd4fdc", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "7299d9e757c87440926dfea4b3c9a697e2e6fc65", "title": "Advancements in hybrid energy storage systems for enhancing renewable energy-to-grid integration", "abstract": "The global energy sector is currently undergoing a transformative shift mainly driven by the ongoing and increasing demand for clean, sustainable, and reliable energy solutions. However, integrating renewable energy sources (RES), such as wind, solar, and hydropower, introduces major challenges due to the intermittent and variable nature of RES, affecting grid stability and reliability. Hybrid energy storage systems (HESS), which combine multiple energy storage devices (ESDs), present a promising solution by leveraging the complementary strengths of each technology involved. This comprehensive review examines recent advancements in grid-connected HESS, focusing on their components, design considerations, control strategies, and applications. It provides a detailed analysis of technological progress in various ESDs and the critical role of power conversion, control, energy management, and cooling systems in optimizing HESS performance. Highlighting case studies of some notable and successful HESS implementations across the globe, we illustrate practical applications and identify the benefits and challenges encountered. By addressing these challenges, HESS can significantly enhance the efficiency and reliability of RES, supporting the shift towards a sustainable and resilient energy infrastructure. The paper concludes by identifying future research directions, highlighting the development of intelligent control systems, sustainable materials, and efficient recycling processes to ensure the widespread adoption and long-term viability of HESS.", "year": 2024, "publicationDate": "2024-07-20", "publicationTypes": ["JournalArticle", "Review"], "venue": "Sustainable Energy Research", "journal": {"name": "Sustainable Energy Research", "volume": "11"}, "citationCount": 182, "referenceCount": 149, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1186/s40807-024-00120-4", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2005391185", "name": "A. M. Adeyinka"}, {"authorId": "1517655943", "name": "Oladapo Christopher Esan"}, {"authorId": "1581837580", "name": "A. Ijaola"}, {"authorId": "79428279", "name": "P. Farayibi"}], "url": "https://www.semanticscholar.org/paper/7299d9e757c87440926dfea4b3c9a697e2e6fc65", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "5e913714d5ab91c3020d5955b8084e8d47f03978", "title": "Sustainable CO2 Refrigeration System for Fish Cold Storage Facility Using a Renewable Integrated System with Solar, Wind and Tidal Energy for Cape Verde—Analyzing Scenarios", "abstract": "This study compares four feasible alternative solutions for an integrated cold storage system in the city of Tarrafal, Santiago, Cape Verde. Integrated systems using grid electricity are compared with autonomous systems generating electrical energy from renewable sources, alongside various types of refrigeration facility systems. Its objective is to assess the energy efficiency, financial feasibility, and environmental impact across four scenarios. Scenario 1 utilizes two R134a refrigeration units powered by the public grid. Scenario 2 employs a transcritical R744 (CO2) system using grid electricity. Scenario 3 incorporates R744 and autonomous renewable energy. Scenario 4 employs R744 for refrigeration with seawater heat exchange and autonomous renewable energy sources. The findings favor Scenario 4, emitting 15,882 kg CO2 eq with a 5-year return on investment. Autonomous electricity production in this scenario reduces emissions by 95%. Despite an initial cost of EUR 769,172.00, Scenario 3 demonstrates financial viability, contributing to energy sustainability. This autonomous production reduces emissions by 360,697 kg CO2 compared to conventional systems, highlighting the positive impact of local renewable energy integration.", "year": 2024, "publicationDate": "2024-05-18", "publicationTypes": ["JournalArticle"], "venue": "Sustainability", "journal": {"name": "Sustainability"}, "citationCount": 15, "referenceCount": 41, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2071-1050/16/10/4259/pdf?version=1716022404", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2302617766", "name": "João Garcia"}, {"authorId": "2302499298", "name": "Arian Semedo"}], "url": "https://www.semanticscholar.org/paper/5e913714d5ab91c3020d5955b8084e8d47f03978", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "2b2036ed534dfeb553cf8aa7a418c90ab7e24f0d", "title": "HyDesign: a tool for sizing optimization of grid-connected hybrid power plants including wind, solar photovoltaic, and lithium-ion batteries", "abstract": "Abstract. Hybrid renewable power plants consisting of collocated wind, solar photovoltaic (PV), and lithium-ion battery storage connected behind a single grid connection can provide additional value to the owners and society in comparison to individual technology plants, such as those that are only wind or only PV. The hybrid power plants considered in this article are connected to the grid and share electrical infrastructure costs across different generation and storing technologies. In this article, we propose a methodology for sizing hybrid power plants as a nested-optimization problem: with an outer sizing optimization and an internal operation optimization. The outer sizing optimization maximizes the net present values over capital expenditures and compares it with standard designs that minimize the levelized cost of energy. The sizing problem formulation includes turbine selection (in terms of rated power, specific power, and hub height), a wind plant wake loss surrogate, simplified wind and PV degradation models, battery degradation, and operation optimization of an internal energy management system. The problem of outer sizing optimization is solved using a new parallel “efficient global optimization” algorithm. This new algorithm is a surrogate-based optimization method that ensures a minimal number of model evaluations but ensures a global scope in the optimization. The methodology presented in this article is available in an open-source tool called HyDesign. The hybrid sizing algorithm is applied for a peak power plant use case at different locations in India where renewable energy auctions impose a monetary penalty when energy is not supplied at peak hours. We compare the hybrid power plant sizing results when using two different objective functions: the levelized cost of energy (LCoE) or the relative net present value with respect to the total capital expenditure costs (NPV/CH). Battery storage is installed only on NPV/CH-based designs, while the hybrid design, including wind, solar, and battery, only occurs on the site with good wind resources. Wind turbine selection on this site prioritizes cheaper turbines with a lower hub height and lower rated power. The number of batteries replaced changes at the different sites, ranging between two or three units over the lifetime. A significant oversizing of the generation in comparison to the grid connection occurs on all NPV/CH-based designs. As expected LCoE-based designs are a single technology with no batteries.\n", "year": 2024, "publicationDate": "2024-04-04", "publicationTypes": ["JournalArticle"], "venue": "Wind Energy Science", "journal": {"name": "Wind Energy Science"}, "citationCount": 23, "referenceCount": 47, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://wes.copernicus.org/articles/9/759/2024/wes-9-759-2024.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2124093010", "name": "J. P. Murcia León"}, {"authorId": "2212815001", "name": "H. Habbou"}, {"authorId": "2265099894", "name": "M. Friis-Møller"}, {"authorId": "2265067606", "name": "Megha Gupta"}, {"authorId": "2264929713", "name": "Rujie Zhu"}, {"authorId": "2265346055", "name": "Kaushik Das"}], "url": "https://www.semanticscholar.org/paper/2b2036ed534dfeb553cf8aa7a418c90ab7e24f0d", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "358d6575a41282a8eee1488c1ad61c347bbfa425", "title": "Advancements and Challenges in Integrating Renewable Energy Sources into Distribution Grid Systems: A Comprehensive Review", "abstract": "\n The issues in integrating renewable energy sources (RES) into distribution grid structures are thoroughly examined in this research. It highlights how important this integration is to updating the energy system and attaining environmental goals. The study explores the specific problems confronted by means of on-grid power structures, along with overall performance metrics and compatibility issues. Additionally, it presents a thorough assessment of the attributes for various RES hybrid systems, together with technology from the fields of solar, wind, batteries, and biomass. to be able to spotlight the significance of innovative solutions inside the dispersed technology environment, the integration of RES with CCHP structures is investigated. This study addresses the numerous problems with RES integration into the grid to better comprehend their intricacies. The viability of RES integration is supported by real-world case studies that provide operational examples of dispersed generation systems. The study concludes by discussing the technical, financial, and grid-related problems associated with distributed generating systems' limits and highlighting the contribution of cutting-edge technology and artificial intelligence to their removal. In conclusion, the report highlights the development toward smarter grids and improved distributed generating capacities as the essential component of a robust and sustainable energy future.", "year": 2024, "publicationDate": "2024-05-10", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of energy resources technology", "journal": {"name": "Journal of Energy Resources Technology"}, "citationCount": 66, "referenceCount": 0, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2301048640", "name": "Surender Singh"}, {"authorId": "2108499004", "name": "Saurabh Singh"}], "url": "https://www.semanticscholar.org/paper/358d6575a41282a8eee1488c1ad61c347bbfa425", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "061d2336fd0d9ebcedcf2598dd1d1e9ac41c9dc5", "title": "Technoeconomic Analysis and Optimization of Hybrid Solar-Wind-Hydrodiesel Renewable Energy Systems Using Two Dispatch Strategies", "abstract": "Sustainable generation is impacted by the adoption of renewable energy, the growth of energy markets, and economic strategies. This paper offers a sustainable strategy and a technoeconomic analysis of off-grid hybrid energy systems (HES) in remote islands of Iran, including Lavan, Larak, and Failaka, utilizing PV module, wind turbine, and hydrokinetic turbines. Hourly wind speed, solar irradiation, and hydrovelocity have been implemented under load following (LF) and cycle charging (CC) dispatch strategies in order to ascertain the most appropriate systems. Lavan Island achieves the winning HES with a CC dispatch strategy, which consists of 3 hydroelectric turbines, 1 wind turbine, 349 kW of solar power, 150 kW of generator power, 316 kWh of batteries, and 287 kW of the converter. This ideal HES, which generates a consistent generation profile and reasonable net present cost (NPC) and cost of energy (COE) of M0.160$ and $0.013 kWh, respectively, can be practically attained in these areas. LF-controlled optimal solutions use less fuel than CC-based ones, leading to a higher share of renewable energy. Compared to Larak and Lavan, the CC- and LF-controlled options on Failaka Island generate cleaner electricity with emissions that are 57% and 44% lower. Regarding the ability to recoup the project’s initial investment costs, long-term energy production would be more financially viable than short-term. Short-term projects with higher financial uncertainty due to the salvage cost should use the CC method.", "year": 2023, "publicationDate": "2023-01-04", "publicationTypes": [], "venue": "International Journal of Photoenergy", "journal": {"name": "International Journal of Photoenergy"}, "citationCount": 27, "referenceCount": 51, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://downloads.hindawi.com/journals/ijp/2023/3101876.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2153166877", "name": "Tiansheng Chen"}, {"authorId": "152176857", "name": "Minglei Wang"}, {"authorId": "30112805", "name": "R. Babaei"}, {"authorId": "2131921794", "name": "Mohammad Esmaeili Safa"}, {"authorId": "143789897", "name": "A. Shojaei"}], "url": "https://www.semanticscholar.org/paper/061d2336fd0d9ebcedcf2598dd1d1e9ac41c9dc5", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "7b8a7374fb3e9eb7309e258c09d338be19f72437", "title": "RETRACTED ARTICLE: Optimization of off-grid hybrid renewable energy systems for cost-effective and reliable power supply in Gaita Selassie Ethiopia", "abstract": "This paper explores scenarios for powering rural areas in Gaita Selassie with renewable energy plants, aiming to reduce system costs by optimizing component numbers to meet energy demands. Various scenarios, such as combining solar photovoltaic (PV) with pumped hydro-energy storage (PHES), utilizing wind energy with PHES, and integrating a hybrid system of PV, wind, and PHES, have been evaluated based on diverse criteria, encompassing financial aspects and reliability. To achieve the results, meta-heuristics such as the Multiobjective Gray wolf optimization algorithm (MOGWO) and Multiobjective Grasshopper optimization algorithm (MOGOA) were applied using MATLAB software. Moreover, optimal component sizing has been investigated utilizing real-time assessment data and meteorological data from Gaita Sillasie, Ethiopia. Metaheuristic optimization techniques were employed to pinpoint the most favorable loss of power supply probability (LPSP) with the least cost of energy (COE) and total life cycle cost (TLCC) for the hybrid system, all while meeting operational requirements in various scenarios. The Multi-Objective Grey Wolf Optimization (MOGWO) technique outperformed the Multi-Objective Grasshopper Optimization Algorithm (MOGOA) in optimizing the problem, as suggested by the results. Furthermore, based on MOGWO findings, the hybrid solar PV-Wind-PHES system demonstrated the lowest COE (0.126€/kWh) and TLCC (€6,897,300), along with optimal satisfaction of the village's energy demand and LPSP value. In the PV-Wind-PHSS scenario, the TLCC and COE are 38%, 18%, 2%, and 1.5% lower than those for the Wind-PHS and PV-PHSS scenarios at LPSP 0%, according to MOGWO results. Overall, this research contributes valuable insights into the design and implementation of sustainable energy solutions for remote communities, paving the way for enhanced energy access and environmental sustainability.", "year": 2024, "publicationDate": "2024-05-13", "publicationTypes": ["JournalArticle"], "venue": "Scientific Reports", "journal": {"name": "Scientific Reports", "volume": "14"}, "citationCount": 45, "referenceCount": 71, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s41598-024-61783-z.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2301195564", "name": "Elsabet Ferede Agajie"}, {"authorId": "1492126833", "name": "T. Agajie"}, {"authorId": "2194455606", "name": "Isaac Amoussou"}, {"authorId": "1416587881", "name": "A. Fopah-Lele"}, {"authorId": "2123129780", "name": "Wirnkar Basil Nsanyuy"}, {"authorId": "2258162337", "name": "Baseem Khan"}, {"authorId": "2222435048", "name": "Mohit Bajaj"}, {"authorId": "2292721993", "name": "I. Zaitsev"}, {"authorId": "2267559704", "name": "E. Tanyi"}], "url": "https://www.semanticscholar.org/paper/7b8a7374fb3e9eb7309e258c09d338be19f72437", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "9c17c94da0c6d2697731b687584c627098a67ff3", "title": "An Innovative Converterless Solar PV Control Strategy for a Grid Connected Hybrid PV/Wind/Fuel-Cell System Coupled With Battery Energy Storage", "abstract": "The proposed work addresses the modeling, control, energy management and operation of hybrid grid connected system with wind-PV-Battery Energy Storage System (BESS) integrated with Fuel Cell (FC) and Electrolyzer. A hybrid PV-Wind-FC with electrolyzer consisting of BESS with the least number of control loops and converters has been proposed. The proposed hybrid system presents a cost efficient solution for integrating PV into a hybrid system by eliminating the PV converter. This includes the design of controllers for grid-connected hybrid systems with a renewable distributed generator (Wind and PV) as a primary source, BESS as a secondary source and FC with Electrolyzer as a tertiary source. In addition, the lead compensator along with integrator is used for obtaining enough phase margin and removing steady state error completely. It increases the stability of the controller and adds phase shift $\\varphi _{s}$ at a cross gain frequency ( $\\omega _{cut}$ ). The Grid Side Controller (GSC) is capable of providing frequency support to the utility grid, when it is linked to the grid. In the proposed configuration, PV power is maximized and injected into grid through GSC. Rotor Side Converter (RSC) and GSC ensure the support for sharing the burden of the grid station. Moreover, the proposed controller of BESS with coordination of FC eliminates the effect of intermittency of power generated from wind and PV. Excess power production by renewable distribution generation is used by Electrolyzer to generate hydrogen. This hydrogen is further used by FC when there is not enough power generation due to unfavorable weather conditions. The energy management has been presented to fulfill the load profile, avoid BESS overcharging and to minimize the intermittency and fluctuation of Wind and PV sources. This method guarantees steady power flow and service continuity. The Simulink model of the proposed system results validate the efficiency of the proposed hybrid system as compared to the conventional hybrid system reported in the literature. The modeling of the proposed system and analysis has been demonstrated using the MATLAB Simulink model. Lastly, the energy management of the system has also been examined and compared with the conventional power system.", "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "IEEE Access", "journal": {"name": "IEEE Access", "pages": "23245-23259", "volume": "11"}, "citationCount": 156, "referenceCount": 59, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://ieeexplore.ieee.org/ielx7/6287639/6514899/10058965.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "145724777", "name": "M. M. Gulzar"}, {"authorId": "46610250", "name": "A. Iqbal"}, {"authorId": "101013761", "name": "Daud Sibtain"}, {"authorId": "117730948", "name": "M. Khalid"}], "url": "https://www.semanticscholar.org/paper/9c17c94da0c6d2697731b687584c627098a67ff3", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "99bf19929fcf001eb5a0d3e0c6778a7a9bf62362", "title": "Research on multiobjective capacity configuration optimization of grid‐connected wind–solar–storage microgrid system based on improved BWO algorithm", "abstract": "How to effectively utilize renewable energy and improve the economic efficiency of microgrid system and its ability to consume renewable energy has become one of the main problems facing China at present. In response to this challenge, this paper establishes a multiobjective capacity optimization model with the minimum levelized cost of energy, the maximum proportion of renewable energy consumption, and the minimum comprehensive system cost. Based on this model, a new improved beluga whale optimization algorithm is proposed to solve the multiobjective optimization problem in the capacity allocation process of wind–solar–storage microgrid system with the goal of ensuring that the microgrid can meet the maximum load demand at different moments throughout the year. In this paper, opposition‐based learning, artificial bee colony, dynamic opposite, and beluga whale optimization are combined to improve the population diversity and convergence accuracy, thereby enhancing the optimization performance of the algorithm. Finally, after finding the optimal Pareto front solution, the Technique for Order Preference by Similarity to an Ideal Solution is used to help decision‐makers select the optimal solution. Using real load data and meteorological data, the results of this paper show that the multiobjective capacity allocation optimization method of grid‐connected scenic storage microgrid system based on the improved beluga whale optimization algorithm can improve the economics of the wind–solar–storage microgrid system and promote the photovoltaic consumption simultaneously, providing a solution for the realization of low‐carbon power and regional economic development. The best‐found levelized cost of energy for the wind–solar–storage microgrid system is 0.192 yuan/kWh.", "year": 2024, "publicationDate": "2024-06-01", "publicationTypes": ["JournalArticle"], "venue": "Energy Science & Engineering", "journal": {"name": "Energy Science & Engineering", "pages": "2365 - 2384", "volume": "12"}, "citationCount": 14, "referenceCount": 34, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ese3.1727", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2306051215", "name": "Ziheng Wang"}, {"authorId": "2306004353", "name": "Tao Wang"}, {"authorId": "2258070039", "name": "Qunfeng Niu"}, {"authorId": "2305804834", "name": "Jianfeng Wu"}, {"authorId": "2112108585", "name": "Mingwei Li"}, {"authorId": "2306056635", "name": "Shuaiqi Zhu"}], "url": "https://www.semanticscholar.org/paper/99bf19929fcf001eb5a0d3e0c6778a7a9bf62362", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "a7d184f4d6584a3d9c96963a8b02d0cbf4c11fb2", "title": "Optimal Modeling and Feasibility Analysis of Grid-Interfaced Solar PV/Wind/Pumped Hydro Energy Storage Based Hybrid System", "abstract": "Access to inexpensive, clean energy is a key factor in a country’s ability to grow sustainably The production of electricity using fossil fuels contributes significantly to global warming and is becoming less and less profitable nowadays. This work therefore proposes to study the different possible scenarios for the replacement of light fuel oil (LFO) thermal power plants connected to the electrical network in northern Cameroon by renewable energy plants. Several scenarios such as the combination of solar photovoltaic (PV) with a pumped hydro storage system (PHSS), Wind and PHSS and PV-Wind-PHSS have been studied. The selected scenarios are evaluated based on two factors such as the system’s total cost (TC) and the loss of load probability (LOLP). To achieve the results, metaheuristics such the non-dominated sorting whale optimization algorithm (NSWOA) and non-dominated sorting genetic algorithm-II (NSGA-II) have been applied under MATLAB software. The optimal sizing of the components was done using hourly meteorological data and the hourly power generated by the thermal power plants connected to the electrical grid. Both algorithms provided satisfactory results. However, the total cost in the PV-PHSS, Wind-PHSS, and PV-Wind-PHSS scenarios with NSWOA is, respectively, 1%, 6%, and 0.2% lower than with NSGA-II. According to NSWOA results, the total cost for the PV-Wind-PHSS scenario at LOLP 0% is 4.6% and 17% less than the Wind-PHS and PV-PHSS scenarios, respectively. The profitability study of all three scenarios showed that the project is profitable regardless of the scenario considered.", "year": 2023, "publicationDate": "2023-01-09", "publicationTypes": [], "venue": "Sustainability", "journal": {"name": "Sustainability"}, "citationCount": 80, "referenceCount": 70, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2071-1050/15/2/1222/pdf?version=1673600070", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2194455606", "name": "Isaac Amoussou"}, {"authorId": "145232749", "name": "E. Tanyi"}, {"authorId": "2112244315", "name": "Ahmed A. Ali"}, {"authorId": "1492126833", "name": "T. Agajie"}, {"authorId": "145724089", "name": "B. Khan"}, {"authorId": "2200203717", "name": "Julien Brito Ballester"}, {"authorId": "2123129780", "name": "Wirnkar Basil Nsanyuy"}], "url": "https://www.semanticscholar.org/paper/a7d184f4d6584a3d9c96963a8b02d0cbf4c11fb2", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "acfcb65f6af6b7e4c99f22de64e9fdfa6f98dfd5", "title": "Optimized Sizing of Energy Management System for Off-Grid Hybrid Solar/Wind/Battery/Biogasifier/Diesel Microgrid System", "abstract": "Recent advances in electric grid technology have led to sustainable, modern, decentralized, bidirectional microgrids (MGs). The MGs can support energy storage, renewable energy sources (RESs), power electronics converters, and energy management systems. The MG system is less costly and creates less CO2 than traditional power systems, which have significant operational and fuel expenses. In this paper, the proposed hybrid MG adopts renewable energies, including solar photovoltaic (PV), wind turbines (WT), biomass gasifiers (biogasifier), batteries’ storage energies, and a backup diesel generator. The energy management system of the adopted MG resources is intended to satisfy the load demand of Basra, a city in southern Iraq, considering the city’s real climate and demand data. For optimal sizing of the proposed MG components, a meta-heuristic optimization algorithm (Hybrid Grey Wolf with Cuckoo Search Optimization (GWCSO)) is applied. The simulation results are compared with those achieved using Particle Swarm Optimization (PSO), Genetic Algorithms (GA), Grey Wolf Optimization (GWO), Cuckoo Search Optimization (CSO), and Antlion Optimization (ALO) to evaluate the optimal sizing results with minimum costs. Since the adopted GWCSO has the lowest deviation, it is more robust than the other algorithms, and their optimal number of component units, annual cost, and Levelized Cost Of Energy (LCOE) are superior to the other ones. According to the optimal annual analysis, LCOE is 0.1192 and the overall system will cost about USD 2.6918 billion.", "year": 2023, "publicationDate": "2023-03-04", "publicationTypes": [], "venue": "Mathematics", "journal": {"name": "Mathematics"}, "citationCount": 67, "referenceCount": 66, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2227-7390/11/5/1248/pdf?version=1678107807", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "153552635", "name": "Ali M. Jasim"}, {"authorId": "46238341", "name": "Basil H. Jasim"}, {"authorId": "52214090", "name": "F. Băiceanu"}, {"authorId": "5881678", "name": "B. Neagu"}], "url": "https://www.semanticscholar.org/paper/acfcb65f6af6b7e4c99f22de64e9fdfa6f98dfd5", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "13491cca5c057ba0487b6d993fc0dd2dc1c0efaf", "title": "Optimizing microgrid integration of renewable energy for sustainable solutions in off/on-grid communities", "abstract": "Rising energy costs, climate change impacts, and transmission losses have increased demand for renewable energy sources and decentralized solutions. As more people seek smart living and working environments, integrated smart microgrids powered by hybrid renewable systems have become attractive solutions for off-grid and on-grid communities. This study proposes designing a solar-wind-battery hybrid microgrid supplying a medical load et al.-Ain Al-Sokhna, Egypt. The optimization objectives aim to minimize the loss of power supply probability (LPSP %) and the levelized cost of energy (LCOE, $/kWh). A key consideration when designing and optimizing hybrid microgrids is the energy management strategy, which coordinates different generation sources and fluctuating load demand. Therefore, optimization algorithms were applied to balance energy flows while meeting loads, mitigating weather impacts, and preventing overcharging/deep discharge of battery storage. Models of wind turbines, photovoltaic panels, and battery storage were developed to simulate and analyze proposed microgrid operations. A multi-objective optimization approach evaluated LPSP and LCOE metrics using transit search, grey wolf, and particle swarm algorithms to find optimal system configurations. The optimization algorithms demonstrated varying performances in minimizing the multi-objective functions for the on-grid and off-grid microgrids. The particle-swarm optimization technique is the best solution for the off-grid system, which contains PV, wind, and battery storage, with a minimum LCOE of 0.3435 $/kWh and an LPSP of 4.5334%. Meanwhile, the transit-search optimization algorithm found the optimal solution for the on-grid configuration according to the objective function, yielding an LCOE of 0.116 $/kWh and an LPSP value of 3.0639 × 10−16. Statistical analysis confirmed that the algorithms generally exhibited stable and robust optimization capabilities. Of the methods, transit search was the most effective overall optimization approach.", "year": 2024, "publicationDate": "2024-12-01", "publicationTypes": ["JournalArticle"], "venue": "Journal of Electrical Systems and Information Technology", "journal": {"name": "Journal of Electrical Systems and Information Technology", "volume": "11"}, "citationCount": 19, "referenceCount": 50, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1186/s43067-024-00186-6", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2337251633", "name": "Amal A. Hassan"}, {"authorId": "3214935", "name": "D. Atia"}], "url": "https://www.semanticscholar.org/paper/13491cca5c057ba0487b6d993fc0dd2dc1c0efaf", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "acbad13d97ead081cdfeda1af500ab8d29dd64a0", "title": "A Cost-Effective Energy Management Approach for On-Grid Charging of Plug-in Electric Vehicles Integrated with Hybrid Renewable Energy Sources", "abstract": "Alternative energy sources have significantly impacted the global electrical sector by providing continuous power to consumers. The deployment of renewable energy sources in order to serve the charging requirements of plug-in electric vehicles (PEV) has become a crucial area of research in emerging nations. This research work explores the techno-economic and environmental viability of on-grid charging of PEVs integrated with renewable energy sources in the Surat region of India. The system is designed to facilitate power exchange between the grid network and various energy system components. The chosen location has contrasting wind and solar potential, ensuring diverse renewable energy prospects. PEV charging hours vary depending on the location. A novel metaheuristic-based optimization algorithm, the Pufferfish Optimization Algorithm (POA), was employed to optimize system component sizing by minimizing the system objectives including Cost of Energy (COE) and the total net present cost (TNPC), ensuring a lack of power supply probability (LPSP) within a permissible range. Our findings revealed that the optimal PEV charging station configuration is a grid-tied system combining solar photovoltaic (SPV) panels and wind turbines (WT). This setup achieves a COE of USD 0.022/kWh, a TNPC of USD 222,762.80, and a life cycle emission of 16,683.74 kg CO2-equivalent per year. The system also reached a 99.5% renewable energy penetration rate, with 3902 kWh/year of electricity purchased from the grid and 741,494 kWh/year of energy sold back to the grid. This approach could reduce reliance on overburdened grids, particularly in developing nations.", "year": 2024, "publicationDate": "2024-08-22", "publicationTypes": ["JournalArticle"], "venue": "Energies", "journal": {"name": "Energies"}, "citationCount": 15, "referenceCount": 51, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.3390/en17164194", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2265276492", "name": "Mohd Bilal"}, {"authorId": "31122837", "name": "P. Bokoro"}, {"authorId": "2150072011", "name": "Gulshan Sharma"}, {"authorId": "2186910377", "name": "Giovanni Pau"}], "url": "https://www.semanticscholar.org/paper/acbad13d97ead081cdfeda1af500ab8d29dd64a0", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "9cd02f83dc6f54fb1718f30889f4e3bcf19a4461", "title": "An Analysis of Hybrid Renewable Energy-Based Hydrogen Production and Power Supply for Off-Grid Systems", "abstract": "Utilizing renewable energy sources to produce hydrogen is essential for promoting cleaner production and improving power utilization, especially considering the growing use of fossil fuels and their impact on the environment. Selecting the most efficient method for distributing power and capacity is a critical issue when developing hybrid systems from scratch. The main objective of this study is to determine how a backup system affects the performance of a microgrid system. The study focuses on power and hydrogen production using renewable energy resources, particularly solar and wind. Based on photovoltaics (PVs), wind turbines (WTs), and their combinations, including battery storage systems (BSSs) and hydrogen technologies, two renewable energy systems were examined. The proposed location for this study is the northwestern coast of Saudi Arabia (KSA). To simulate the optimal size of system components and determine their cost-effective configuration, the study utilized the Hybrid Optimization Model for Multiple Energy Resources (HOMER) software (Version 3.16.2). The results showed that, when considering the minimum cost of energy (COE), the integration of WTs, PVs, a battery bank, an electrolyzer, and a hydrogen tank brought the cost of energy to almost 0.60 USD/kWh in the system A. However, without a battery bank, the COE increased to 0.72 USD/kWh in the same location because of the capital cost of system components. In addition, the results showed that the operational life of the fuel cell decreased significantly in system B due to the high hours of operation, which will add additional costs. These results imply that long-term energy storage in off-grid energy systems can be economically benefited by using hydrogen with a backup system.", "year": 2024, "publicationDate": "2024-06-12", "publicationTypes": ["JournalArticle"], "venue": "Processes", "journal": {"name": "Processes"}, "citationCount": 16, "referenceCount": 35, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2227-9717/12/6/1201/pdf?version=1718181958", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2283780332", "name": "Yahya Z. Alharthi"}], "url": "https://www.semanticscholar.org/paper/9cd02f83dc6f54fb1718f30889f4e3bcf19a4461", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "3f7d59443feef2689294bc1239832ebf09f29184", "title": "On–off-Grid Optimal Hybrid Renewable Energy Systems for House Units in Iraq", "abstract": "This paper addresses the optimal sizing of Hybrid Renewable Energy Systems (HRESs), encompassing wind, solar, and battery systems, with the aim of delivering reliable performance at a reasonable cost. The focus is on mitigating unscheduled outages on the national grid in Iraq. The proposed On–off-grid HRES method is implemented using MATLAB and relies on an iterative technique to achieve multi-objectives, balancing reliability and economic constraints. The optimal HRES configuration is determined by evaluating various scenarios related to energy flow management, electricity prices, and land cover effects. Consumer requirements regarding cost and reliability are factored into a 2D optimization process. A battery model is developed to capture the dynamic exchange of energy among different renewable sources, battery storage, and energy demands. A detailed case study across fifteen locations in Iraq, including water, desert, and urban areas, revealed that local wind speed significantly affects the feasibility and efficiency of the HRES. Locations with higher wind speeds, such as the Haditha lake region (payback period: 7.8 years), benefit more than urban areas (Haditha city: payback period: 12.4 years). This study also found that not utilizing the battery, particularly during periods of high electricity prices (e.g., 2015), significantly impacts the HRES performance. In the Haditha water area, for instance, this technique reduced the payback period from 20.1 to 7.8 years by reducing the frequency of charging and discharging cycles and subsequently mitigating the need for battery replacement.", "year": 2024, "publicationDate": "2024-05-09", "publicationTypes": ["JournalArticle"], "venue": "Clean Technology", "journal": {"name": "Clean Technologies"}, "citationCount": 12, "referenceCount": 64, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2571-8797/6/2/32/pdf?version=1715247105", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2130754516", "name": "H. Alshamri"}, {"authorId": "2300972347", "name": "Timothy Cockerill"}, {"authorId": "2258206081", "name": "Alison S. Tomlin"}, {"authorId": "1416131129", "name": "Moustafa Al-Damook"}, {"authorId": "1792083523", "name": "M. Al Qubeissi"}], "url": "https://www.semanticscholar.org/paper/3f7d59443feef2689294bc1239832ebf09f29184", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "57ac27213748a213d3229b4cd532b4a981178660", "title": "Design and Implementation of a Hybrid Solar-Wind-Biomass Renewable Energy System considering Meteorological Conditions with the Power System Performances", "abstract": "This paper presents a performance evaluation of an off-grid PV-wind-biomass hybrid energy system for a remote area named Kuakata in Bangladesh considering dispatch strategy-based control, power system response, and reliability analysis-based stability and feasibility study. The simulation and optimization of operations of the system have been done by the HOMER software using the real-time field data of solar radiation, wind speed, and biomass of that particular area for ensuring economical and environmental feasibility offering the least net present cost (NPC), cost of energy (COE), and CO2 emission. The result shows that NPC has been reduced by 88 percent, CO2 emissions have been reduced by 99 percent, the operating cost has been lowered by 99 percent, and COE has been reduced by 92 percent than another available work. Besides, in comparison to traditional power sources, COE has been reduced by 40 percent, NPC has been lowered by 90 percent, and CO2 emissions have been reduced by 99 percent. The proposed system has also been analyzed utilizing DIgSILENT PowerFactory software to find the power system responses, i.e., active, reactive powers, voltage, and frequency responses of the proposed microgrid in a per unit fashion on the occurrence of a three-phase fault. To establish the feasibility of the microgrid, a reliability study considering different reliability indices has also been done. The analyzed hybrid energy system might be applicable to other regions of the world where there are similar climatic conditions.", "year": 2022, "publicationDate": "2022-08-02", "publicationTypes": [], "venue": "International Journal of Photoenergy", "journal": {"name": "International Journal of Photoenergy"}, "citationCount": 38, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://downloads.hindawi.com/journals/ijp/2022/8792732.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2344104549", "name": "Md Delwar Hossen"}, {"authorId": "48196668", "name": "Md. Fokhrul Islam"}, {"authorId": "1491236362", "name": "Md. Fatin Ishraque"}, {"authorId": "31022036", "name": "S. Shezan"}, {"authorId": "143959729", "name": "S. M. Arifuzzaman"}], "url": "https://www.semanticscholar.org/paper/57ac27213748a213d3229b4cd532b4a981178660", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "1aaf502dbd6467dfb0bb794307d00ea7575a2d69", "title": "Challenges and opportunities in optimizing hybrid renewable energy systems for grid stability and socio-economic development in rural Sub-saharan Africa: A narrative review", "abstract": "The global shift towards renewable energy systems is critical for combating climate change, enhancing energy security, and achieving sustainability. Hybrid renewable energy systems, which integrate multiple renewable sources such as solar, wind, and hydropower, promise increased reliability and efficiency in energy generation. However, their integration into national grids presents significant technical, economic, and regulatory challenges. This narrative review systematically analyzes the hurdles and opportunities associated with hybrid renewable energy systems, drawing from diverse case studies and technological advancements. It discusses technical challenges, including grid stability and interconnection compatibility, and economic issues related to high initial investments and financing. Furthermore, the review highlights regulatory barriers and the necessity for supportive frameworks. It concludes with insights into the potential of hybrid systems to foster technological innovation and contribute to sustainable development and climate change mitigation.", "year": 2024, "publicationDate": "2024-12-30", "publicationTypes": ["JournalArticle", "Review"], "venue": "KIU journal of science engineering and technology", "journal": {"name": "KIU journal of science engineering and technology"}, "citationCount": 9, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.59568/kjset-2024-3-2-12", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2343763027", "name": "Eze Val Hyginus Udoka"}, {"authorId": "2344009382", "name": "Emmanuel Innocent Eniru"}, {"authorId": "2344004792", "name": "Victor Adacha Itafe"}, {"authorId": "2343970532", "name": "John Ukagwu Kelechi"}, {"authorId": "2268123225", "name": "C. N. Ugwu"}, {"authorId": "2268123219", "name": "F. C. Ogenyi"}, {"authorId": "2344004991", "name": "Charles Ibeabuchi Mbonu"}], "url": "https://www.semanticscholar.org/paper/1aaf502dbd6467dfb0bb794307d00ea7575a2d69", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "bed1becfb82c895e12583aa690b47b2b89a10c7b", "title": "Optimal design and analysis of a grid‐connected hybrid renewable energy system using HOMER Pro: A case study of Tumbatu Island, Zanzibar", "abstract": "This study addresses the pressing issue of quality electricity access in remote regions, with a specific focus on Tumbatu Island in Tanzania. Most studies on quality improvement concentrate on low‐voltage distribution lines and leave high‐voltage (HV) transmission lines behind. It is essential to address quality issues in HV lines due to their critical role in electricity transmission and distribution infrastructure. The objective of the study is to improve the voltage profile on the island's HV transmission line by identifying the optimal hybrid energy system comprising solar PV, wind turbine, and battery technologies. The study begins by presenting the total power demand and consumption on Tumbatu Island, which are important factors in designing an efficient energy system. The findings reveal a power demand of 7173 kW and a consumption of 28540 kWh/day, with an average scaled value of 1507.9 and 6000 kWh/day. To achieve the desired voltage profile improvement, the research incorporates HOMER Pro software for simulating and analyzing various hybrid system configurations. Essential input parameters, such as costs, resources, technology components, and load, are considered in the simulation process. The software generates a ranked list of options based on the system's net present cost (NPC). The simulation results demonstrate that the integration of solar PV, wind turbine, and HV lines provides a substantial improvement in the voltage profile, increasing it from 29.6 to 31.23 kV during peak demand periods. This solution proves to be the most economically viable, with the lowest NPC of $4,003,851 and a relatively short payback period of 3.79 years. In addition, a sensitivity analysis is performed to identify the most influential parameter in the system's performance. Wind speed is found to have the greatest impact, emphasizing its significance in the design and operation of the hybrid energy system. The implementation of this optimal hybrid renewable energy system on Tumbatu Island will not only improve the voltage profile and meet the island's energy needs but also shall contribute to global efforts in reducing pollution and the cost of electricity to the Tumbatu Island population. Moreover, it addresses the current and future demands for clean energy, underlining its importance in achieving sustainable and accessible electricity in sub‐Saharan Africa and beyond.", "year": 2024, "publicationDate": "2024-04-04", "publicationTypes": ["JournalArticle"], "venue": "Energy Science & Engineering", "journal": {"name": "Energy Science & Engineering", "pages": "2137 - 2163", "volume": "12"}, "citationCount": 19, "referenceCount": 97, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ese3.1735", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2295242345", "name": "Thani R. Said"}, {"authorId": "67285180", "name": "Baraka Kichonge"}, {"authorId": "31373979", "name": "T. Kivevele"}], "url": "https://www.semanticscholar.org/paper/bed1becfb82c895e12583aa690b47b2b89a10c7b", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "17e073cb438dfd317c8484cb3599a360319c732d", "title": "A Comprehensive Review on Opportunities and Challenges of Grid Integration of Renewable Energy Resources", "abstract": "The global shift towards sustainable energy has accelerated the integration of Variable Renewable Energy Resources (VRER), such as solar and wind, into mainstream power generation. While VRER offer immense potential for reducing carbon emissions and advancing energy sustainability, their inherent variability poses unique challenges for seamless integration into existing power grids. This paper comprehensively explores challenges and opportunities associated with the efficient grid integration of VRER. A key focus of the paper is to maintain system stability and reliability while improving the economic benefits of incorporating VRER. By offering a balanced examination of challenges and opportunities, this paper aims to guide stakeholders in developing effective policies, technologies, and strategies for navigating the complex landscape of VRER grid integration. Ultimately, the insights presented contribute to realizing a sustainable and resilient future energy system.", "year": 2024, "publicationDate": "2024-04-02", "publicationTypes": ["Conference", "Review"], "venue": "2024 Second International Conference on Smart Technologies for Power and Renewable Energy (SPECon)", "journal": {"name": "2024 Second International Conference on Smart Technologies for Power and Renewable Energy (SPECon)", "pages": "1-6"}, "citationCount": 7, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2171768165", "name": "Shivani Garg"}, {"authorId": "2355620360", "name": "Shivangi Tyagi"}], "url": "https://www.semanticscholar.org/paper/17e073cb438dfd317c8484cb3599a360319c732d", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "2aeab2ed55b90eebb6d0e369d34c6d18e048fc7b", "title": "Grid-Connected Hybrid Renewable Energy System Under Various Operating Conditions", "abstract": "Due to the rapid increase in electricity demand, and the need to tackle climate change; renewable energy systems have been utilized considerably in recent years. The world has recently witnessed a dramatic increase in using solar energy based on photovoltaic (PV) technology and wind energy in different applications due to their sustainability, efficient cost, and mature technology. In addition, one of the many advantages of wind and solar based on PV is the possibility of installing them near the load centers in distribution networks. One of the great challenges of renewable energy based on PV and wind is that they have an intermittent nature. Combing wind and PV in one site increases the reliability of such renewable systems due to the complementary nature of these sources. This paper investigates a grid-connected hybrid renewable system based on wind and PV without storage devices. The performance is evaluated in such hybrid renewable scheme with considering different operating conditions and simulation scenarios. MATLAB/SIMULINK has been used to design and test the hybrid renewable system to evaluate the system's performance.", "year": 2024, "publicationDate": "2024-03-04", "publicationTypes": ["Conference"], "venue": "IEEE International Energy Conference", "journal": {"name": "2024 IEEE 8th Energy Conference (ENERGYCON)", "pages": "1-6"}, "citationCount": 7, "referenceCount": 29, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "9409182", "name": "F. Alsokhiry"}], "url": "https://www.semanticscholar.org/paper/2aeab2ed55b90eebb6d0e369d34c6d18e048fc7b", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "cbe0ae36d1805023045628693b9d7e080b346c57", "title": "A Comprehensive Review of the Current Status of Smart Grid Technologies for Renewable Energies Integration and Future Trends: The Role of Machine Learning and Energy Storage Systems", "abstract": "The integration of renewable energy sources (RES) into smart grids has been considered crucial for advancing towards a sustainable and resilient energy infrastructure. Their integration is vital for achieving energy sustainability among all clean energy sources, including wind, solar, and hydropower. This review paper provides a thoughtful analysis of the current status of the smart grid, focusing on integrating various RES, such as wind and solar, into the smart grid. This review highlights the significant role of RES in reducing greenhouse gas emissions and reducing traditional fossil fuel reliability, thereby contributing to environmental sustainability and empowering energy security. Moreover, key advancements in smart grid technologies, such as Advanced Metering Infrastructure (AMI), Distributed Control Systems (DCS), and Supervisory Control and Data Acquisition (SCADA) systems, are explored to clarify the related topics to the smart grid. The usage of various technologies enhances grid reliability, efficiency, and resilience are introduced. This paper also investigates the application of Machine Learning (ML) techniques in energy management optimization within smart grids with the usage of various optimization techniques. The findings emphasize the transformative impact of integrating RES and advanced smart grid technologies alongside the need for continued innovation and supportive policy frameworks to achieve a sustainable energy future.", "year": 2024, "publicationDate": "2024-08-19", "publicationTypes": ["JournalArticle", "Review"], "venue": "Energies", "journal": {"name": "Energies"}, "citationCount": 134, "referenceCount": 92, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/1996-1073/17/16/4128/pdf?version=1724073832", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2315755244", "name": "M. Kiasari"}, {"authorId": "2317432879", "name": "Mahdi Ghaffari"}, {"authorId": "2292538927", "name": "Hamed H. Aly"}], "url": "https://www.semanticscholar.org/paper/cbe0ae36d1805023045628693b9d7e080b346c57", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "05306d8c3c2a528b4431ca542b2388f87d2f5dda", "title": "Joint Optimal Scheduling of Renewable Energy Regional Power Grid With Energy Storage System and Concentrated Solar Power Plant", "abstract": "Under the path of global low-carbon development, increasing the proportion of renewable energy in the power grid will become the main goal in the future. But, it will also aggravate the problem of wind and solar curtailment. A joint optimal scheduling model of a renewable energy regional power grid with an energy storage system and concentrated solar power plant is proposed in this study. The proposed model takes the lowest comprehensive operation cost of the power grid as the optimization goal and considers various constraints of concentrated solar power plants, energy storage systems, thermal power units, wind power, and photovoltaic power generation. Finally, a modified IEEE 9-bus system is used to verify the validity. The results show that the model can effectively improve the system node voltage, promote the accommodation of wind and solar power, and alleviate the peak shaving of thermal power units under the premise of optimal economy pressure.", "year": 2022, "publicationDate": "2022-07-11", "publicationTypes": [], "venue": "Frontiers in Energy Research", "journal": {"volume": "10"}, "citationCount": 14, "referenceCount": 30, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fenrg.2022.941074/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "16325285", "name": "Yannan Dong"}, {"authorId": "30622100", "name": "Zijiao Han"}, {"authorId": "47057387", "name": "Xiangjun Li"}, {"authorId": "50347839", "name": "Shaohua Ma"}, {"authorId": "2204860439", "name": "F. Gao"}, {"authorId": "2108786179", "name": "Wenwen Li"}], "url": "https://www.semanticscholar.org/paper/05306d8c3c2a528b4431ca542b2388f87d2f5dda", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "8d9d5f6d3ec02271bbddbdaa12f1b7bbdfc71c93", "title": "Robust Control for Optimized Islanded and Grid-Connected Operation of Solar/Wind/Battery Hybrid Energy", "abstract": "Wind and solar energy systems are among the most promising renewable energy technologies for electric power generations. Hybrid renewable energy systems (HRES) enable the incorporation of more than one renewable technology, allowing increased reliability and efficiency. Nevertheless, the introduction of variable generation sources in concurrence with the existing system load demand necessitates maintaining the power balance between the components of the HRES. Additionally, the efficiency of the hybrid power supply system is drastically affected by the number of converters interfacing its components. Therefore, to improve the performance of the HRES, this paper proposes a robust sliding mode control strategy for both standalone and grid-connected operation. The control strategy achieves maximum power point tracking for both the renewable energy sources and stabilizes the DC-bus and load voltages irrespective of the disturbances, change in load demand, variations of irradiance level, temperature, and wind speed ensuring an efficient energy management. Furthermore, the solar PV system is directly linked to the DC-bus obviating the need for redundant interfacing boost converters with decreased costs and reduced system losses. Lyapunov candidate function is used to prove the asymptotic stability and the convergence of the entire system. The robustness of the proposed control strategy is tested and validated under various conditions of HRES, demonstrating its efficacy and performance under various conditions of the HRES.", "year": 2022, "publicationDate": "2022-05-08", "publicationTypes": [], "venue": "Sustainability", "journal": {"name": "Sustainability"}, "citationCount": 44, "referenceCount": 28, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2071-1050/14/9/5673/pdf?version=1652335108", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1965927884", "name": "Muhammad Maaruf"}, {"authorId": "1380670204", "name": "K. Khan"}, {"authorId": "117730948", "name": "M. Khalid"}], "url": "https://www.semanticscholar.org/paper/8d9d5f6d3ec02271bbddbdaa12f1b7bbdfc71c93", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "bedbd71a5183bf3ffb22186c2cb8f275633cb6ca", "title": "Optimal Power Flow of Hybrid Wind/Solar/Thermal Energy Integrated Power Systems Considering Costs and Emissions via a Novel and Efficient Search Optimization Algorithm", "abstract": "The OPF problem has significant importance in a power system’s operation, planning, economic scheduling, and security. Today’s electricity grid is rapidly evolving, with increased penetration of renewable power sources (RPSs). Conventional optimal power flow (OPF) has non-linear constraints that make it a highly non-linear, non-convex optimization problem. This complex problem escalates further with the integration of renewable energy resource (RES), which are generally intermittent in nature. This study suggests a new and effective improved optimizer via a TFWO algorithm (turbulent flow of water-based optimization), namely the ITFWO algorithm, to solve non-linear and non-convex OPF problems in energy networks with integrated solar photovoltaic (PV) and wind turbine (WT) units (being environmentally friendly and clean in nature). OPF in the energy networks is an optimization problem proposed to discover the optimal settings of an energy network. The OPF modeling contains the forecasted electric energy of WT and PV by considering the voltage value at PV and WT buses as decision parameters. Forecasting the active energy of PV and WT units has been founded on the real-time measurements of solar irradiance and wind speed. Eight scenarios are analyzed on the IEEE 30-bus test system in order to determine a cost-effective schedule for thermal power plants with different objectives that reflect fuel cost minimization, voltage profile improvement, emission gases, power loss reduction, and fuel cost minimization with consideration of the valve point effect of generation units. In addition, a carbon tax is considered in the goal function in the examined cases in order to investigate its effect on generator scheduling. A comparison of the simulation results with other recently published algorithms for solving OPF problems is made to illustrate the effectiveness and validity of the proposed ITFWO algorithm. Simulation results show that the improved turbulent flow of water-based optimization algorithm provides an effective and robust high-quality solution of the various optimal power-flow problems. Moreover, results obtained using the proposed ITFWO algorithm are either better than, or comparable to, those obtained using other techniques reported in the literature. The utility of solar and wind energy in scheduling problems has been proposed in this work.", "year": 2023, "publicationDate": "2023-04-10", "publicationTypes": ["JournalArticle"], "venue": "Applied Sciences", "journal": {"name": "Applied Sciences"}, "citationCount": 25, "referenceCount": 106, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2076-3417/13/8/4760/pdf?version=1681176122", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2258609362", "name": "Ali S. Alghamdi"}], "url": "https://www.semanticscholar.org/paper/bedbd71a5183bf3ffb22186c2cb8f275633cb6ca", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "f565b9fcff466f39dc15f6b2570832df5645f3d1", "title": "Mitigating Impact of High Power Ramp Rates in Utility Grid Integrated Wind–Solar System Using an RLMAT Adaptive Control Strategy", "abstract": "With the unremitting progress in renewable energy based systems into a sizeable contributor in global energy mix, the need to address challenges associated with their inherent power variability has also risen. The high power-ramp rates experienced during sudden wind gusts and cloud passing are known to impact the security of the power grid, especially in remotely-located wind-solar systems. These challenges are further intensified with sudden connection/disconnection of large local loads in the system, which demand power at a high ramp rate. This work deals with the use of a coordinated control strategy for power converters, to limit the grid power-ramp rate during the aforementioned high power-ramp events (HPREs). The deficit power during HPREs is absorbed by the energy storage system (ESS). The reference currents for ramp rate limiting control are computed using a robust least mean absolute third (RLMAT) adaptive filter. The RLMAT filter further assists in improving the grid currents power quality in presence of nonlinear, unbalanced and poor power factor local loads in the system. The effectiveness of the control strategy is evaluated through both simulation analysis and test results obtained from a laboratory-scale prototype.", "year": 2023, "publicationDate": "2023-03-01", "publicationTypes": [], "venue": "IEEE transactions on energy conversion", "journal": {"name": "IEEE Transactions on Energy Conversion", "pages": "343-354", "volume": "38"}, "citationCount": 20, "referenceCount": 29, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2109605558", "name": "Souvik Das"}, {"authorId": "49191190", "name": "Bhim Singh"}], "url": "https://www.semanticscholar.org/paper/f565b9fcff466f39dc15f6b2570832df5645f3d1", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "1c40ae0307fdca780b251bd88800efaf944c5427", "title": "Assessing Economic Complementarity in Wind–Solar Hybrid Power Plants Connected to the Brazilian Grid", "abstract": "The share of electricity generation from Variable Renewable Energy Sources (VRES) has increased over the last 20 years. Despite promoting the decarbonization of the energy mix, these sources bring negative characteristics to the energy mix, such as power ramps, load mismatch, unpredictability, and fluctuation. One of the ways to mitigate these characteristics is the hybridization of power plants. This paper evaluates the benefits of hybridizing a plant using an AI-based methodology for optimizing the wind–solar ratio based on the Brazilian regulatory system. For this study, the hybrid plant was modeled using data collected over a period of 10 months. The measurements were obtained using two wind profilers (LIDAR and SODAR) and a sun tracker (Solys 2) as part of the EOSOLAR R&D project conducted in the state of Maranhão, Brazil. After the power plant modeling, a Genetic Algorithm (GA) was used to determine the optimal wind–solar ratio, considering costs with transmission systems. The algorithm achieved a monthly profit increase of more than 39% with an energy curtailment inferior to 1%, which indicates economic complementarity. Later, the same methodology was also applied to verify the wind–solar ratio’s sensitivity to solar energy pricing. The results show that a price increase of 15% would change the power plant’s optimal configuration.", "year": 2023, "publicationDate": "2023-05-31", "publicationTypes": ["JournalArticle"], "venue": "Sustainability", "journal": {"name": "Sustainability"}, "citationCount": 15, "referenceCount": 31, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2071-1050/15/11/8862/pdf?version=1685533674", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2190350760", "name": "Rafael B. S. Veras"}, {"authorId": "9455170", "name": "C. B. M. Oliveira"}, {"authorId": "30743473", "name": "Shigeaki L. de Lima"}, {"authorId": "144072287", "name": "O. Saavedra"}, {"authorId": "48881174", "name": "D. Q. Oliveira"}, {"authorId": "33986086", "name": "F. Pimenta"}, {"authorId": "2190319456", "name": "Denivaldo C. P. Lopes"}, {"authorId": "123743910", "name": "A. R. Torres Junior"}, {"authorId": "1380440015", "name": "F. Neto"}, {"authorId": "32786479", "name": "Ramon M. de Freitas"}, {"authorId": "2753370", "name": "A. Assireu"}], "url": "https://www.semanticscholar.org/paper/1c40ae0307fdca780b251bd88800efaf944c5427", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "48b0cc2f716f93513ad04dd695e870244bc1fc14", "title": "Economic and environmental assessment of solar-wind-biomass hybrid renewable energy system supplying rural settlement load", "abstract": "Abstract Hybrid renewable energy systems are becoming a popular option for rural electrification due to environmental impacts caused by fossil fuels like coal and oil. Iran is a developing country with many renewable energy sources, but most Iranian power plants use non-renewable resources to generate electricity. This study aims to present a hybrid renewable energy system consisting of photovoltaic panels, wind turbines, and biogas generator for rural electrification in Fars province, Iran. The utilization of this off-grid system prevents the development of fossil fuel power plants and CO2 emissions. The optimization problem is solved using the HOMER Pro software, and sensitivity analyses obtain optimal system configurations on input biomass rate, biomass price, and inflation rate parameters. The inflation rate and biomass price are directly related to the cost of electricity (COE). The results show that the COE in optimal systems ranges from 0.128 to $0.223/kW h. Increasing the biomass price from 20 to $60/ton reduces the biogas generator's power generation by at least 86%. The most optimal economic system involves a biogas generator (150 kW), photovoltaic panels (80.7 kW), batteries, and converter. The environmental assessment indicates that CO2 emissions from proposed hybrid renewable energy systems are negligible compared to a coal-based power plant and the grid. Reducing CO2 in the presented approach can save more than $8000 a year.", "year": 2020, "publicationDate": "2020-12-01", "publicationTypes": [], "venue": "Sustainable Energy Technologies and Assessments", "journal": {"name": "Sustainable Energy Technologies and Assessments"}, "citationCount": 157, "referenceCount": 55, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "49793994", "name": "M. Jahangir"}, {"authorId": "108459409", "name": "R. Cheraghi"}], "url": "https://www.semanticscholar.org/paper/48b0cc2f716f93513ad04dd695e870244bc1fc14", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "5a347b27e12a88ea8c7321622608c672a6b32ffc", "title": "Synergizing Wind and Solar Power: An Advanced Control System for Grid Stability", "abstract": "In response to the escalating global energy crisis, the motivation for this research has been derived from the need for sustainable and efficient energy solutions. A gap in existing renewable energy systems, particularly in terms of stability and efficiency under variable environmental conditions, has been recognized, leading to the introduction of a novel hybrid system that combines photovoltaic (PV) and wind energy. The innovation of this study lies in the methodological approach that has been adopted, integrating dynamic modeling with a sophisticated control mechanism. This mechanism, a blend of model predictive control (MPC) and particle swarm optimization (PSO), has been specifically designed to address the fluctuations inherent in PV and wind power sources. The methodology involves a detailed stability analysis using Lyapunov’s theorem, a critical step distinguishing this system from conventional renewable energy solutions. The integration of MPC and PSO, pivotal in enhancing the system’s adaptability and optimizing the maximum power point tracking (MPPT) process, improves control efficiency across key components like the doubly fed induction generator (DFIG), rectifier-sourced converter (RSC), and grid-side converter (GSC). Through rigorous MATLAB simulations, the system’s robust response to changing solar irradiance and wind velocities has been demonstrated. The key findings confirm the system’s ability to maintain stable power generation, underscoring its practicality and efficiency in renewable energy integration. Not only has this study filled a crucial gap in renewable energy control systems, but it has also set a precedent for future research in sustainable energy technologies.", "year": 2024, "publicationDate": "2024-01-17", "publicationTypes": ["JournalArticle"], "venue": "Sustainability", "journal": {"name": "Sustainability"}, "citationCount": 26, "referenceCount": 31, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2071-1050/16/2/815/pdf?version=1705501337", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2175916771", "name": "Chaymae Boubii"}, {"authorId": "30753287", "name": "I. Kafazi"}, {"authorId": "2331736478", "name": "R. Bannari"}, {"authorId": "2254093994", "name": "Brahim El Bhiri"}, {"authorId": "3169595", "name": "B. Bossoufi"}, {"authorId": "50566664", "name": "Hossam Kotb"}, {"authorId": "98374121", "name": "Kareem M. AboRas"}, {"authorId": "2275881189", "name": "A. Emara"}, {"authorId": "2325312948", "name": "Badr Nasiri"}], "url": "https://www.semanticscholar.org/paper/5a347b27e12a88ea8c7321622608c672a6b32ffc", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "8d9b5c72254ac54f08e8f74500efe1b2bb56e6c3", "title": "A Strategy for Multi-Objective Energy Optimization in Smart Grid Considering Renewable Energy and Batteries Energy Storage System", "abstract": "Multi-objective energy optimization is pivotal for reliable and secure power system operation. However, multi-objective energy optimization is challenging due to interdependent and conflicting objectives. Thus, a multi-objective optimization model is needed to cater to conflicting objectives. On this note, a multi-objective optimization model is developed, where a non-dominated genetic sorting algorithm is employed to optimize objectives pollution emission, operation cost, and loss of load expectation (LOLE) considering renewable energy sources (RES). RES, like wind and solar, are intermittent and uncertain, which are modelled using a beta probability density function (PDF). The developed method’s effectiveness and applicability are analyzed by implementing it on the 30-bus system, and the results are compared for two cases. Findings reveal that the developed multi-objective optimization model minimizes operation cost, pollution emission, and LOLE by 59%, 7%, and 2.67%, respectively, compared to existing models.", "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "IEEE Access", "journal": {"name": "IEEE Access", "pages": "33872-33886", "volume": "11"}, "citationCount": 63, "referenceCount": 86, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1109/access.2023.3263264", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2449091", "name": "Ahmad Alzahrani"}, {"authorId": "144534758", "name": "Mujeeb U. Rahman"}, {"authorId": "14342306", "name": "Ghulam Hafeez"}, {"authorId": "2142087419", "name": "Gul Rukh"}, {"authorId": "2165194184", "name": "Sajjad Ali"}, {"authorId": "9326596", "name": "S. Murawwat"}, {"authorId": "133958814", "name": "Faizan Iftikhar"}, {"authorId": "38138466", "name": "Syed Irtaza Haider"}, {"authorId": "2115773552", "name": "Muhammad iftikhar Khan"}, {"authorId": "46203973", "name": "A. Abed"}], "url": "https://www.semanticscholar.org/paper/8d9b5c72254ac54f08e8f74500efe1b2bb56e6c3", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "ec741fa289139e4b2bdfe854a61c1489321510a1", "title": "Techno-Economic Comparative Analysis of Grid-Connected and Islanded Hybrid Renewable Energy Systems in 7 Climate Regions, Turkey", "abstract": "The aim of this study is to evaluate the economic, technical, and environmental performances of grid-tied and stand-alone hybrid renewable energy systems (HRESs) in 21 provinces in seven regions of Turkey, considering different regional solar radiation and wind speed diversity. HRES were designed and modeled using the Hybrid Optimization of Multiple Energy Resources software (HOMER PRO) to meet the daily load of 13.26 kWh/day of a household. The analysis results for each province were compared considering the cost of energy, net present cost (NPC), greenhouse gas emissions, renewable fraction (RF), and optimum system configuration. The findings demonstrated that the optimal system configurations are Grid/PV/WT and PV/WT/DG/BESS for grid-tied and stand-alone HRES, respectively. The value of NPC ranges from <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>2,540.00 to <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>8,951.00 for grid-tied HRES, while it varies from <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>23,372.00 to <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>40,858.00 for stand-alone HRES. The provinces of Çanakkale in the Marmara Region and Artvin in the Black Sea Coast Region have the lowest and highest NPC values, respectively, for all systems. The PV capital cost, WT capital cost, BESS capital cost, solar radiation, and wind speed are considered as sensitivity input parameters that might affect the economic output of the HRES in this study. According to the sensitivity analysis, the NPC value as an economic indicator input decreased for both on-grid and off-grid HRES as the wind speed and solar radiation increased. It was also found that when the capital cost of PV panels and WT were changed, the NPC of the stand-alone HRES was in the range of <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>21,402.27-<inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>29,978.89 for the province of Çanakkale, while it was in the range of <inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>37,518.11-<inline-formula> <tex-math notation=\"LaTeX\">$\\$ $ </tex-math></inline-formula>51,939.00 for the province of Artvin. Moreover, when solar radiation and wind speed were increased, the results showed that NPC and CO2 emissions decreased by 9.30% and 9.23%, respectively, for Çanakkale, and by 25.58% and 66.95%, respectively, for Artvin. Finally, the results indicated that the optimal system configuration changes depending on the PV and WT capital cost variations for the grid-tied HRES. This research can be useful for planning grid-tied and stand-alone HRES from different aspects in Turkey, as well as other countries around the world. It contributes to the literature by comparing grid-tied and stand-alone HRES to determine the optimum system configuration and to find the best optimization results in seven regions of Turkey under different climate conditions. In addition, most of the studies related to HRES for residential areas in the literature are reviewed in this research, which intends to serve as a guide for engineers and researchers.", "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle", "Review"], "venue": "IEEE Access", "journal": {"name": "IEEE Access", "pages": "48797-48825", "volume": "11"}, "citationCount": 39, "referenceCount": 94, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://ieeexplore.ieee.org/ielx7/6287639/10005208/10128107.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "31223881", "name": "Onur Ayan"}, {"authorId": "2916131", "name": "B. Turkay"}], "url": "https://www.semanticscholar.org/paper/ec741fa289139e4b2bdfe854a61c1489321510a1", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "03b2430285871159f07748313c08041cdc7f2382", "title": "Batteries or hydrogen or both for grid electricity storage upon full electrification of 145 countries with wind-water-solar?", "abstract": "Summary Grids require electricity storage. Two emerging storage technologies are battery storage (BS) and green hydrogen storage (GHS) (hydrogen produced and compressed with clean-renewable electricity, stored, then returned to electricity with a fuel cell). An important question is whether GHS alone decreases system cost versus BS alone or BS + GHS. Here, energy costs are modeled in 145 countries grouped into 24 regions. Existing conventional hydropower (CH) storage is used along with new BS and/or GHS. A method is developed to treat CH for both baseload and peaking power. In four regions, only CH is needed. In five, CH + BS is the lowest cost. Otherwise, CH + BS + GHS is the lowest cost. CH + GHS is never the lowest cost. A metric helps estimate whether combining GHS with BS reduces cost. In most regions, merging (versus separating) grid and non-grid hydrogen infrastructure reduces cost. In sum, worldwide grid stability may be possible with CH + BS or CH + BS + GHS. Results are subject to uncertainties.", "year": 2024, "publicationDate": "2024-01-01", "publicationTypes": ["JournalArticle"], "venue": "iScience", "journal": {"name": "iScience", "volume": "27"}, "citationCount": 35, "referenceCount": 27, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "http://www.cell.com/article/S2589004224002098/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2261716813", "name": "Mark Z. Jacobson"}], "url": "https://www.semanticscholar.org/paper/03b2430285871159f07748313c08041cdc7f2382", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "9fedbfd599ba7b3c9dbfbd4dcb64e5d09c845b8d", "title": "A Metaheuristic Approach Based Feasibility Assessment and Design of Solar, Wind, and Grid Powered Charging of Electric Vehicles", "abstract": "This study assesses the integration of renewable energy sources with grid-connected systems to power electric vehicle charging stations (EVCSs) in Riyadh, Kingdom of Saudi Arabia (KSA), emphasizing its significance for sustainable development. An environmentally friendly EVCS model and a novel metaheuristic optimization technique, the Giza Pyramids Construction Algorithm (GPCA) is employed, to determine the optimal sizing of system components. The objective is to ensure dependability, as determined by the lack of power supply probability (LPSP), while minimizing the levelized cost of energy (LCOE) and total net present cost (TNPC). We assess the efficacy of other algorithms in scaling system components by contrasting the performance of the GPCA with those of the Artificial Hummingbird Algorithm (AHA), Flower Pollination Algorithm (FPA), and Whale Optimization Algorithm (WOA). The study also examines the impact of climatic, financial, and technical factors on system costs, providing insights into the challenges, opportunities, and socio-economic factors influencing the deployment of EV infrastructure in KSA. Findings suggest that the optimal EVCS configuration is a solar photovoltaic/wind turbine (SPV/WT) grid-tied system, resulting in an LCOE of ${\\$}$ 0.0796/kWh, a TNPC of ${\\$}$ 102,042, and an annual CO2 emission reduction of 18,840 kg. The system achieves a 67.9% renewable penetration rate with 30.8% annual grid electricity purchase and 32.4% sale. Sensitivity analysis on renewable parameters is also conducted, demand charges, grid purchase prices, discount rates, and inflation rates to assess their impact on the system’s economic variables. By identifying current constraints and potential strategies, our study aims to inform policy-making and investment decisions for expanding electric vehicle charging infrastructure, with broader implications for developing nations.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "IEEE Access", "journal": {"name": "IEEE Access", "pages": "82599-82621", "volume": "12"}, "citationCount": 22, "referenceCount": 55, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1109/access.2024.3411291", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "119669844", "name": "Fayez Alanazi"}, {"authorId": "2305376584", "name": "Mohd Bilal"}, {"authorId": "12459409", "name": "Ammar Armghan"}, {"authorId": "1491246993", "name": "Md. Reyaz Hussan"}], "url": "https://www.semanticscholar.org/paper/9fedbfd599ba7b3c9dbfbd4dcb64e5d09c845b8d", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "b83a5c987d25cd4d72bddaa3adb1c8332371096b", "title": "Operating characteristics analysis and capacity configuration optimization of wind-solar-hydrogen hybrid multi-energy complementary system", "abstract": "Wind and solar energy are the important renewable energy sources, while their inherent natures of random and intermittent also exert negative effect on the electrical grid connection. As one of multiple energy complementary route by adopting the electrolysis technology, the wind-solar-hydrogen hybrid system contributes to improving green power utilization and reducing its fluctuation. Therefore, the moving average method and the hybrid energy storage module are proposed, which can smooth the wind-solar power generation and enhance the system energy management. Moreover, the optimization of system capacity configuration and the sensitive analysis are implemented by the MATLAB program platform. The results indicate that the 10-min grid-connected volatility is reduced by 38.7% based on the smoothing strategy, and the internal investment return rate can reach 13.67% when the electricity price is 0.04 $/kWh. In addition, the annual coordinated power and cycle proportion of the hybrid energy storage module are 80.5% and 90%, respectively. The developed hybrid energy storage module can well meet the annual coordination requirements, and has lower levelized cost of electricity. This method provides reasonable reference for designing and optimizing the wind-solar-hydrogen complementary system.", "year": 2023, "publicationDate": "2023-12-29", "publicationTypes": ["JournalArticle"], "venue": "Frontiers in Energy Research", "journal": {"name": "Frontiers in Energy Research"}, "citationCount": 8, "referenceCount": 48, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fenrg.2023.1305492/pdf?isPublishedV2=False", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2277092037", "name": "Wei Su"}, {"authorId": "2237102779", "name": "Qi Li"}, {"authorId": "2224965124", "name": "Shuoshuo Wang"}, {"authorId": "2277085484", "name": "Wenjin Zheng"}, {"authorId": "2238136974", "name": "Zhang Bai"}, {"authorId": "2277047303", "name": "Yunyi Han"}, {"authorId": "2237062433", "name": "Zhenyue Yu"}], "url": "https://www.semanticscholar.org/paper/b83a5c987d25cd4d72bddaa3adb1c8332371096b", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "b73751a9bc7905edcf3e4c6329bc0016463b6b56", "title": "Renewable energy sources‐based hybrid microgrid system for off‐grid electricity solution for rural communities", "abstract": "Rural electrification is a crucial component of meeting sustainable development goals. In Pakistan, load shedding and power outages are frequent. According to the current data, Pakistan is experiencing a shortfall of power between 6000 and 6500 MW. Microgrid technology has the potential to provide a solution to this problem in an efficient and low‐cost manner. This paper proposes the development of a hybrid microgrid system (HMGS) for rural communities. For that purpose, a technological analysis of the HMGS system for rural electrification is performed. Solar photovoltaic (PV) and wind resource‐based renewable energy systems are considered in this work for the electrification of rural areas of Pakistan. A hybrid PV/wind system is designed using MATLAB software. Simulation results show that a 230‐V sinusoidal output voltage has been produced by the proposed model. The advantage of this model is that it minimizes the impact of transients and provides a sinusoidal output waveform.", "year": 2023, "publicationDate": "2023-07-31", "publicationTypes": ["JournalArticle"], "venue": "Energy Science &amp; Engineering", "journal": {"name": "Energy Science & Engineering", "pages": "3486 - 3499", "volume": "11"}, "citationCount": 33, "referenceCount": 36, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ese3.1535", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2108626923", "name": "Majid Ali"}, {"authorId": "2105860821", "name": "Mohsin Riaz"}, {"authorId": "2006361672", "name": "M. A. Koondhar"}, {"authorId": "2005062452", "name": "Muhammad Sarfraz Akram"}, {"authorId": "145110486", "name": "J. Guerrero"}, {"authorId": "2241541473", "name": "J. Vasquez"}, {"authorId": "145724089", "name": "B. Khan"}], "url": "https://www.semanticscholar.org/paper/b73751a9bc7905edcf3e4c6329bc0016463b6b56", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "1a1d719beea377dab7c38c0ba691e2b682ade743", "title": "A Comparative Study of the Optimal Sizing and Management of Off-Grid Solar/Wind/Diesel and Battery Energy Systems for Remote Areas", "abstract": "Electrification in rural areas is relatively costly compared to urban areas. Therefore, the aim of this research is to identify the best combination of hybrid renewable energy systems (HRESs) to satisfy the load demand in a sustainable and cost-efficient way. The techno-economic study of stand-alone hybrid photovoltaic–wind turbine–diesel–battery-converter energy systems based on the hybrid optimization model for electric renewable (HOMER) simulation has been analyzed for various locations in the Tamil Nadu state, India. Various combinations of the systems have been compared and analyzed based on the performance of their technical parameters, costs, the electrical power production of each source, and unmet load. The findings indicated that the off-grid solar–wind–diesel–battery configuration is the most economical for all the sites among other system configurations. Comparing with conventional diesel generators among all the locations, a combination of solar/wind/diesel/battery is the economically best design for Thoothukudi, with the least and most reliable solution in terms of net present cost and cost of energy. Also, the impact of intermittent variables becomes significant, so sensitivity analysis for the various parameters has been carried out. The study finds that the least cost of electricity and the net present cost of electricity for Thoothukudi are achieved at 0.266 $/kWh and 138,197 $, respectively. This is economical compared to a stand-alone diesel system where the obtained COE is $1.88 and the NPC is $977523. In the stand-alone diesel operating mode, 41854 kg of CO2 is produced, which is higher than CO2 emissions associated with any other renewable energy systems. According to the results, the Kanyakumari location outperforms in terms of producing environmental pollutants with emission of 1,020 kg/y CO2 at their best. Moreover, the results of the proposed study imply that the proposed renewable energy system in remote sites could be a more economical measure.", "year": 2021, "publicationDate": "2021-11-12", "publicationTypes": [], "venue": "Frontiers in Energy Research", "journal": {"volume": "9"}, "citationCount": 52, "referenceCount": 50, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fenrg.2021.752043/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "117035185", "name": "M. Thirunavukkarasu"}, {"authorId": "9352857", "name": "Yashwant Sawle"}], "url": "https://www.semanticscholar.org/paper/1a1d719beea377dab7c38c0ba691e2b682ade743", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "2fedf8258e46f9b8e48b26773bc78e9b38013563", "title": "Comparative assessment of solar photovoltaic-wind hybrid energy systems: A case for Philippine off-grid islands", "abstract": null, "year": 2021, "publicationDate": "2021-12-01", "publicationTypes": [], "venue": null, "journal": {"name": "Renewable Energy", "pages": "1589-1607", "volume": "179"}, "citationCount": 57, "referenceCount": 127, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1486113704", "name": "J. D. Pascasio"}, {"authorId": "94763796", "name": "Eugene A. Esparcia"}, {"authorId": "1576442838", "name": "Michael T. Castro"}, {"authorId": "92665765", "name": "J. Ocon"}], "url": "https://www.semanticscholar.org/paper/2fedf8258e46f9b8e48b26773bc78e9b38013563", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "29bb8c39edfc49edbfab9107b7e97593349b5dfa", "title": "Coupled thermo-electrical dispatch strategy with AI forecasting for optimal sizing of grid-connected hybrid renewable energy systems", "abstract": "In multi-energy systems the full utilisation of the generated energy is a challenge. Integrating heat and electricity supply at the system level design could provide an opportunity to address this challenge. In this paper we introduce and examine two coupled thermal-electrical dispatch strategies for grid-connected hybrid multi-energy systems supplying electrical and thermal demand loads. The dispatch strategy employs forecasting of energy resources and demand loads to prioritise supplying the thermal load in times of renewable surplus. Four forecasting algorithms, namely, baseline forecast, Facebook Prophet (FBP), Neural Prophet (NP), and Long Short-Term Memory model (LSTM) are implemented and used to generate annual forecast data for solar irradiance, wind speed, and thermal and electrical demand loads. To integrate forecast data within the dispatch strategy, new parameters are proposed to quantify the expected available energy within the forecast time horizon. A building complex for the Department of Education in the UK is used for conducting a system design case study. A genetic algorithm-based multi-objective optimisation with the levelised costs of electricity and heat as two objectives is conducted. The results show that the proposed dispatch algorithm produces systems with reduced levelised costs compared to the base case of using utility gas and electricity. Forecasting is particularly useful in reducing cost of heat, as it can prioritise supplying the thermal load in times of renewable surplus. LSTM proved to be the most accurate forecasting algorithm for this case, where the data has strong seasonality and trends. The main contribution of this work is to propose and demonstrate the effectiveness of tightly coupling thermo-electrical dispatch algorithms of HRES from the design stage, and how to effectively integrate forecast data within such algorithms.", "year": 2023, "publicationDate": "2023-10-01", "publicationTypes": ["JournalArticle"], "venue": "Energy Conversion and Management", "journal": {"name": "Energy Conversion and Management"}, "citationCount": 40, "referenceCount": 48, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.enconman.2023.117460", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2331525529", "name": "F. Kahwash"}, {"authorId": "101777009", "name": "B. Barakat"}, {"authorId": "2461868", "name": "A. Maheri"}], "url": "https://www.semanticscholar.org/paper/29bb8c39edfc49edbfab9107b7e97593349b5dfa", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "dd47caac6f31a7cddf86891d66f31023b11e4e77", "title": "Hybrid renewable energy systems: the value of storage as a function of PV-wind variability", "abstract": "As shares of variable renewable energy (VRE) on the electric grid increase, sources of grid flexibility will become increasingly important for maintaining the reliability and affordability of electricity supply. Lithium-ion battery energy storage has been identified as an important and cost-effective source of flexibility, both by itself and when coupled with VRE technologies like solar photovoltaics (PV) and wind. In this study, we explored the current and future value of utility-scale hybrid energy systems comprising PV, wind, and lithium-ion battery technologies (PV-wind-battery systems). Using a price-taker model with simulated hourly energy and capacity prices, we simulated the revenue-maximizing dispatch of a range of PV-wind-battery configurations across Texas, from the present through 2050. Holding PV capacity and point-of-interconnection capacity constant, we modeled configurations with varying wind-to-PV capacity ratios and battery-to-PV capacity ratios. We found that coupling PV, wind, and battery technologies allows for more effective utilization of interconnection capacity by increasing capacity factors to 60%–80%+ and capacity credits to close to 100%, depending on battery capacity. We also compared the energy and capacity values of PV-wind and PV-wind-battery systems to the corresponding stability coefficient metric, which describes the location-and configuration-specific complementarity of PV and wind resources. Our results show that the stability coefficient effectively predicts the configuration-location combinations in which a smaller battery component can provide comparable economic performance in a PV-wind-battery system (compared to a PV-battery system). These PV-wind-battery hybrids can help integrate more VRE by providing smoother, more predictable generation and greater flexibility.", "year": 2023, "publicationDate": "2023-09-19", "publicationTypes": ["JournalArticle"], "venue": "Frontiers in Energy Research", "journal": {"name": "Frontiers in Energy Research"}, "citationCount": 33, "referenceCount": 92, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fenrg.2023.1036183/pdf?isPublishedV2=False", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "1659480155", "name": "Anna H. Schleifer"}, {"authorId": "1422551264", "name": "D. Harrison-Atlas"}, {"authorId": "2244469329", "name": "Wesley J. Cole"}, {"authorId": "2281586026", "name": "Caitlin Murphy"}], "url": "https://www.semanticscholar.org/paper/dd47caac6f31a7cddf86891d66f31023b11e4e77", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "732c69600905a374fec91c81d82dba12fc89f4ad", "title": "Hybridized Renewable Energy for Smart Vehicle-to-Grid (V2G) Systems", "abstract": "Wind and sunlight are increasingly being exploited as energy supplies that never run out. Additionally, renewable energy resources, including sun, wind, and geothermal heat, are being used for different technologies. It was considered the use of hybridized wind-solar energy resources in smart vehicle technology. A thorough understanding of an integrated framework of the hybridized renewable energy for smart vehicle-to-grid (V2G) systems is essential and required to further identify and perhaps maximize existing opportunities. Aiming to develop a vehicle-to-grid (V2G) system where the smart vehicle runs on stored sunshine and wind energy, and vehicle batteries store energy and release it to the electricity grid in peak demand periods. To achieve this aim, mathematical models for solar and wind systems were created and entire 24-h simulations were run for case studies of three smart vehicles, which were assessed for different scenarios and circumstances, using the MATLAB/SIMULINK environment. The estimated values obtained were home load 10 MW, power factor 0.15 MVA, industrial load 0.16 MVA, and smart car-to-grid, solar panel farm, and wind farm power of 4 MW, 8 MW, and 4.5 MW, respectively. Therefore, the hybridized wind-solar energy sources were applicable for all three smart vehicles considered.", "year": 2023, "publicationDate": "2023-10-29", "publicationTypes": ["JournalArticle"], "venue": "Energy Exploration &amp; Exploitation", "journal": {"name": "Energy Exploration & Exploitation", "pages": "292 - 308", "volume": "42"}, "citationCount": 19, "referenceCount": 23, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://journals.sagepub.com/doi/pdf/10.1177/01445987231209770", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1571462148", "name": "Sairoel Amertet"}, {"authorId": "4909435", "name": "G. Gebresenbet"}], "url": "https://www.semanticscholar.org/paper/732c69600905a374fec91c81d82dba12fc89f4ad", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "e6be279b33edbfba609676640dc088c667b0eb03", "title": "An Optimized Framework of the Integrated Renewable Energy and Power Quality Model for the Smart Grid", "abstract": "The smart grid’s structure is distinctive because it incorporates numerous cutting-edge communication and sensor technologies. It is challenging to manage smart grids using conventional power grids’ unified optimum delivery strategy effectively. This work offers a smart grid power production and maintenance collaborative optimization framework with renewable energy based on power generation and maintenance analysis. The operating costs of conventional units, the price of generating solar or wind power, and the cost of maintaining units are the problems of objective functions; the constraints taken into account are primarily system constraints. The genetic algorithm (GA) is used in this research to examine the optimization solution strategy. Depending on the properties of the system, various loads, power sources, and constraints are considered. The difficulty of adjusting load scheduling is transformed into a control problem by developing an efficient objective function. When uncertain system components are considered, the real-time control system can dynamically alter load scheduling to meet the needs of the actual system. In this study, the real-time algorithm put forward in this research is based on a strategy that satisfies the load optimization requirement and achieves dynamic compensation for unpredictable changes in renewable energy power generation. Moreover, the simulation compares the proposed algorithm capabilities with the existing algorithms/study, demonstrating the effectiveness of the suggested approach.", "year": 2023, "publicationDate": "2023-04-14", "publicationTypes": ["JournalArticle"], "venue": "International Transactions on Electrical Energy Systems", "journal": {"name": "International Transactions on Electrical Energy Systems"}, "citationCount": 24, "referenceCount": 33, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://downloads.hindawi.com/journals/itees/2023/6769690.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2116962680", "name": "Naveen Kumar"}, {"authorId": "152754694", "name": "Gopal Singh"}, {"authorId": "1491943773", "name": "Hailemichael Kebede"}], "url": "https://www.semanticscholar.org/paper/e6be279b33edbfba609676640dc088c667b0eb03", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "40717807a533e3a7dff04dc8174132a0199546e2", "title": "Ancillary services from wind and solar energy in modern power grids: A comprehensive review and simulation study", "abstract": "Renewable energy sources like wind and solar have increased demand for surplus power capacity. The demand is primarily fueled by the growing impact of forecasting errors associated with these intermittent energy sources. Implementing advanced control methods for automatic generation control (AGC) is essential to integrate wind and solar power with conventional generation sources to balance the power system and reduce reliance on traditional reserves. Therefore, this paper comprehensively overviews solar and wind energy integration in the AGC framework to provide optimal grid ancillary services. Initially, the paper presents an overview of the basic equations used to integrate reserve power from the photovoltaic (PV) system by employing the de-loading strategy. Subsequently, a comprehensive review is conducted on integrating the PV system in AGC strategies to provide grid ancillary services. The study also analyzes the contribution of wind power in AGC services using relevant equations and past practices. The paper presents a real-time dynamic control strategy to optimize the dispatch of the AGC unit by integrating the operating reserves from wind energy systems in conjunction with thermal power systems. The study simulates an 8-bus, 5-machine model using the Dig-SILENT Power Factory. The findings reveal that utilizing operating reserves from wind power can significantly reduce large-scale forecasting errors in massively renewable energy resources (RES) integrated power systems, thereby ensuring the necessary system operational security and reducing the reliance on traditional generating units.", "year": 2024, "publicationDate": "2024-05-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Renewable and Sustainable Energy", "journal": {"name": "Journal of Renewable and Sustainable Energy"}, "citationCount": 47, "referenceCount": 49, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.aip.org/aip/jrse/article-pdf/doi/10.1063/5.0206835/19962325/032701_1_5.0206835.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2137198173", "name": "Kaleem Ullah"}, {"authorId": "51311325", "name": "Majid Ali Tunio"}, {"authorId": "2248654949", "name": "Zahid Ullah"}, {"authorId": "2301059182", "name": "Muhammad Talha Ejaz"}, {"authorId": "2190312685", "name": "Muhammad Junaid Anwar"}, {"authorId": "2277526725", "name": "Muhammad Ahsan"}, {"authorId": "2301848626", "name": "Ritesh Tandon"}], "url": "https://www.semanticscholar.org/paper/40717807a533e3a7dff04dc8174132a0199546e2", "_run_id": "TUsuxq3NqxXhIrggr", "_dataset_id": "V7HtsBHZNuwVmehZ1"}
{"paperId": "65e4f03b7fc0f5e23fa98023027e09ac5d222a6b", "title": "Dietary sodium intake and mortality: NHANES. The Faculty 31st International Society and Federation of Cardiology 10-day Teaching Seminar in Cardiovascular Disease, Epidemiology and Prevention. National Health and Nutrition Examination Survey.", "abstract": null, "year": 1998, "publicationDate": "1998-09-19", "publicationTypes": ["LettersAndComments", "Review"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          987-8\n        ", "volume": "352 9132"}, "citationCount": 19, "referenceCount": 6, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673605615425/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2411790331", "name": "Neil R. Poulter"}], "url": "https://www.semanticscholar.org/paper/65e4f03b7fc0f5e23fa98023027e09ac5d222a6b", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "d20aeceb4ebdca8e29d3cfd129a148e48165f827", "title": "Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study", "abstract": "Summary Background Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. We aimed to assess the effects on respiratory and cardiovascular responses of walking down a busy street with high levels of pollution compared with walking in a traffic-free area with lower pollution levels in older adults. Methods In this randomised, crossover study, we recruited men and women aged 60 years and older with angiographically proven stable ischaemic heart disease or stage 2 Global initiative for Obstructive Lung Disease (GOLD) COPD who had been clinically stable for 6 months, and age-matched healthy volunteers. Individuals with ischaemic heart disease or COPD were recruited from existing databases or outpatient respiratory and cardiology clinics at the Royal Brompton & Harefield NHS Foundation Trust and age-matched healthy volunteers using advertising and existing databases. All participants had abstained from smoking for at least 12 months and medications were taken as recommended by participants' doctors during the study. Participants were randomly assigned by drawing numbered disks at random from a bag to do a 2 h walk either along a commercial street in London (Oxford Street) or in an urban park (Hyde Park). Baseline measurements of participants were taken before the walk in the hospital laboratory. During each walk session, black carbon, particulate matter (PM) concentrations, ultrafine particles, and nitrogen dioxide (NO2) concentrations were measured. Findings Between October, 2012, and June, 2014, we screened 135 participants, of whom 40 healthy volunteers, 40 individuals with COPD, and 39 with ischaemic heart disease were recruited. Concentrations of black carbon, NO2, PM10, PM2.5, and ultrafine particles were higher on Oxford Street than in Hyde Park. Participants with COPD reported more cough (odds ratio [OR] 1·95, 95% CI 0·96–3·95; p<0·1), sputum (3·15, 1·39–7·13; p<0·05), shortness of breath (1·86, 0·97–3·57; p<0·1), and wheeze (4·00, 1·52–10·50; p<0·05) after walking down Oxford Street compared with Hyde Park. In all participants, irrespective of their disease status, walking in Hyde Park led to an increase in lung function (forced expiratory volume in the first second [FEV1] and forced vital capacity [FVC]) and a decrease in pulse wave velocity (PWV) and augmentation index up to 26 h after the walk. By contrast, these beneficial responses were attenuated after walking on Oxford Street. In participants with COPD, a reduction in FEV1 and FVC, and an increase in R5–20 were associated with an increase in during-walk exposure to NO2, ultrafine particles and PM2.5, and an increase in PWV and augmentation index with NO2 and ultrafine particles. In healthy volunteers, PWV and augmentation index were associated both with black carbon and ultrafine particles. Interpretation Short-term exposure to traffic pollution prevents the beneficial cardiopulmonary effects of walking in people with COPD, ischaemic heart disease, and those free from chronic cardiopulmonary diseases. Medication use might reduce the adverse effects of air pollution in individuals with ischaemic heart disease. Policies should aim to control ambient levels of air pollution along busy streets in view of these negative health effects. Funding British Heart Foundation.", "year": 2017, "publicationDate": "2017-12-05", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "339 - 349", "volume": "391"}, "citationCount": 42, "referenceCount": 36, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673617326430/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "49556850", "name": "R. Sinharay"}, {"authorId": "46272579", "name": "J. Gong"}, {"authorId": "35229765", "name": "B. Barratt"}, {"authorId": "1398816758", "name": "P. Ohman-Strickland"}, {"authorId": "2247275309", "name": "Sabine Ernst"}, {"authorId": "2057028412", "name": "F. Kelly"}, {"authorId": "2108099340", "name": "J. Zhang"}, {"authorId": "2072421423", "name": "Peter Collins"}, {"authorId": "4866288", "name": "P. Cullinan"}, {"authorId": "2107172661", "name": "K. Chung"}], "url": "https://www.semanticscholar.org/paper/d20aeceb4ebdca8e29d3cfd129a148e48165f827", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "d49205eca447638b95ca44e3dbf8b7f4e294c3d5", "title": "Statins: new American guidelines for prevention of cardiovascular disease.", "abstract": null, "year": 2013, "publicationDate": "2013-11-30", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1762-5\n        ", "volume": "382 9907"}, "citationCount": 492, "referenceCount": 23, "influentialCitationCount": 14, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "5957531", "name": "P. Ridker"}, {"authorId": "38075616", "name": "N. Cook"}], "url": "https://www.semanticscholar.org/paper/d49205eca447638b95ca44e3dbf8b7f4e294c3d5", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "c18ef9392d9496ba71061c62d7a2514728a1c3c5", "title": "Nurse-coordinated multidisciplinary, family-based cardiovascular disease prevention programme (EUROACTION) for patients with coronary heart disease and asymptomatic individuals at high risk of cardiovascular disease: a paired, cluster-randomised controlled trial.", "abstract": null, "year": 2008, "publicationDate": "2008-06-14", "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1999-2012\n        ", "volume": "371 9629"}, "citationCount": 560, "referenceCount": 47, "influentialCitationCount": 17, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2114998683", "name": "David R. Wood"}, {"authorId": "5317289", "name": "K. Kotseva"}, {"authorId": "50675785", "name": "S. Connolly"}, {"authorId": "2262100", "name": "C. Jennings"}, {"authorId": "38091998", "name": "A. Mead"}, {"authorId": "49156428", "name": "Jennifer Jones"}, {"authorId": "47442845", "name": "A. Holden"}, {"authorId": "7568115", "name": "D. Bacquer"}, {"authorId": "32406766", "name": "T. Collier"}, {"authorId": "51265876", "name": "G. Backer"}, {"authorId": "5485185", "name": "O. Faergeman"}], "url": "https://www.semanticscholar.org/paper/c18ef9392d9496ba71061c62d7a2514728a1c3c5", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "102bd9899a4168cced9b9b2b0819c6353a6f08ef", "title": "Cardiovascular prevention guidelines in daily practice: a comparison of EUROASPIRE I, II, and III surveys in eight European countries.", "abstract": null, "year": 2009, "publicationDate": "2009-03-14", "publicationTypes": ["JournalArticle", "Study", "Review"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          929-40\n        ", "volume": "373 9667"}, "citationCount": 869, "referenceCount": 53, "influentialCitationCount": 34, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "5317289", "name": "K. Kotseva"}, {"authorId": "120893977", "name": "D. Wood"}, {"authorId": "2247619659", "name": "G. De Backer"}, {"authorId": "2298116976", "name": "D. De Bacquer"}, {"authorId": "6692827", "name": "K. Pyörälä"}, {"authorId": "2439264", "name": "U. Keil"}], "url": "https://www.semanticscholar.org/paper/102bd9899a4168cced9b9b2b0819c6353a6f08ef", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "b22d5720ce5204bf8c18c7e0eefd0dd04371b12f", "title": "Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial.", "abstract": null, "year": 2008, "publicationDate": "2008-10-04", "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1223-30\n        ", "volume": "372 9645"}, "citationCount": 1017, "referenceCount": 69, "influentialCitationCount": 18, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2248931241", "name": "L. Tavazzi"}, {"authorId": "2242772635", "name": "A. Maggioni"}, {"authorId": "2390789104", "name": "Roberto Marchioli"}, {"authorId": "3480751", "name": "S. Barlera"}, {"authorId": "5448923", "name": "M. Franzosi"}, {"authorId": "2252619048", "name": "R. Latini"}, {"authorId": "2407027135", "name": "Donata Lucci"}, {"authorId": "2239631623", "name": "Gianluigi Nicolosi"}, {"authorId": "2264242992", "name": "Maurizio Porcu"}, {"authorId": "2246147998", "name": "Gianni Tognoni"}], "url": "https://www.semanticscholar.org/paper/b22d5720ce5204bf8c18c7e0eefd0dd04371b12f", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "daa1e31fb5e089ac5c278ec47d570150dc8d0826", "title": "Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study.", "abstract": null, "year": 2008, "publicationDate": "2008-03-15", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          915-22\n        ", "volume": "371 9616"}, "citationCount": 432, "referenceCount": 33, "influentialCitationCount": 29, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "153654062", "name": "K. Sliwa"}, {"authorId": "153849649", "name": "David Wilkinson"}, {"authorId": "145332216", "name": "C. Hansen"}, {"authorId": "4259272", "name": "L. Ntyintyane"}, {"authorId": "6436847", "name": "K. Tibazarwa"}, {"authorId": "10635666", "name": "A. Becker"}, {"authorId": "2240746115", "name": "S. Stewart"}], "url": "https://www.semanticscholar.org/paper/daa1e31fb5e089ac5c278ec47d570150dc8d0826", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "d009be23820367b3312d82b88f8c687fbcdd7b81", "title": "Role of MRI in clinical cardiology.", "abstract": null, "year": 2004, "publicationDate": "2004-06-26", "publicationTypes": ["Review", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2162-71\n        ", "volume": "363 9427"}, "citationCount": 195, "referenceCount": 139, "influentialCitationCount": 7, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "5070204", "name": "G. Constantine"}, {"authorId": "2272873875", "name": "Kesavan Shan"}, {"authorId": "2482207", "name": "S. Flamm"}, {"authorId": "4433590", "name": "M. Sivananthan"}], "url": "https://www.semanticscholar.org/paper/d009be23820367b3312d82b88f8c687fbcdd7b81", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "f2e408e897228ad8256208d7053c17c0838946db", "title": "Integrity and the European Society of Cardiology--reply.", "abstract": null, "year": 2015, "publicationDate": "2015-03-28", "publicationTypes": ["LettersAndComments"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1182\n        ", "volume": "385 9974"}, "citationCount": 0, "referenceCount": 5, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673615606365/pdf", "fieldsOfStudy": ["Medicine", "Political Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Political Science", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "144618228", "name": "F. Pinto"}], "url": "https://www.semanticscholar.org/paper/f2e408e897228ad8256208d7053c17c0838946db", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "1d8096a90ab01bf0ed01ed8f5db542bb7be3ed58", "title": "Statins, risk assessment, and the new American prevention guidelines.", "abstract": null, "year": 2014, "publicationDate": "2014-02-15", "publicationTypes": ["LettersAndComments", "Review"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          600-2\n        ", "volume": "383 9917"}, "citationCount": 61, "referenceCount": 15, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S014067361362348X/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1387460828", "name": "D. Lloyd‐Jones"}, {"authorId": "5863028", "name": "D. Goff"}, {"authorId": "4663019", "name": "N. Stone"}], "url": "https://www.semanticscholar.org/paper/1d8096a90ab01bf0ed01ed8f5db542bb7be3ed58", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "8e64dbd6bd538c71c67701b58745b74a31f3807c", "title": "Identification of intact peanut lectin in peripheral venous blood.", "abstract": null, "year": 1998, "publicationDate": "1998-12-05", "publicationTypes": ["LettersAndComments", "Study"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1831-2\n        ", "volume": "352 9143"}, "citationCount": 84, "referenceCount": 5, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Biology", "Medicine"], "s2FieldsOfStudy": [{"category": "Biology", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2153282838", "name": "Qiang Wang"}, {"authorId": "144778192", "name": "Lu-Gang Yu"}, {"authorId": "34147363", "name": "B. Campbell"}, {"authorId": "80163857", "name": "J. Milton"}, {"authorId": "74263933", "name": "J. Rhodes"}], "url": "https://www.semanticscholar.org/paper/8e64dbd6bd538c71c67701b58745b74a31f3807c", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "0b5142f028ed3eca385d7c57c9c7908da0f8fbdb", "title": "Updated Zika virus recommendations are needed.", "abstract": "818 www.thelancet.com Vol 392 September 8, 2018 4 Fihn SD, Blankenship JC, Alexander KP, et al. 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation 2014; 130: 1749–67.", "year": 2018, "publicationDate": "2018-09-01", "publicationTypes": ["LettersAndComments"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          818-819\n        ", "volume": "392 10150"}, "citationCount": 7, "referenceCount": 5, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673618318270/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "8331768", "name": "M. Vouga"}, {"authorId": "4542282", "name": "D. Musso"}, {"authorId": "6545780", "name": "A. Goorhuis"}, {"authorId": "4286318", "name": "D. Freedman"}, {"authorId": "5816393", "name": "D. Baud"}], "url": "https://www.semanticscholar.org/paper/0b5142f028ed3eca385d7c57c9c7908da0f8fbdb", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "0ed6281447fd7c78ccadab002be489635a5a5ec6", "title": "Department of Error", "abstract": "532 www.thelancet.com Vol 386 August 8, 2015 3 National Drug Evidence Centre. Facts and fi gures. http://www.population-health. manchester.ac.uk/epidemiology/NDEC/ factsandfi gures/ (accessed May 1, 2015). 4 Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D. Segmented regression analysis of interrupted time series studies in medication use research. J Clin Pharm Ther 2002; 27: 299–309. 5 Hinkley DV. Inference about the change-point in a sequence of random variables. Biometrika 1970; 57: 1–17. 6 Wilson W, Taubert KA, Gewitz M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007; 116: 1736–54. 7 Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 2009; 30: 2369–413. weight of evidence on which infective endocarditis guidelines are based. The AHA and ACC and European Society of Cardiology guidelines are based on Level C evidence (expert opinion). Our analysis is a cohort study—Level B evidence—the same as a single randomised controlled trial. Although our results might be controversial, we argue that they alter the available weight of evidence (especially in the absence of a randomised controlled trial). We agree with James Wong and colleagues that infective endocarditis coding has improved, especially since secondary coding became important for measurement of quality indicators. However, we restricted our analysis to primary codes that have always been mandatory and are unlikely to have changed. A full assessment of the National Institute for Cardiovascular Outcomes Research dataset could add important information. We hope that our data will provoke further debate about the value of antibiotic prophylaxis for infective endocarditis and lead to further collaborative research eff orts to assess safety and eff ectiveness and to inform international guidelines.", "year": 2018, "publicationDate": "2018-10-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "The Lancet", "volume": "392"}, "citationCount": 0, "referenceCount": 4, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673618323936/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2114345777", "name": "Xinzhong Cui"}], "url": "https://www.semanticscholar.org/paper/0ed6281447fd7c78ccadab002be489635a5a5ec6", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "29c8bcadb286d32c77365551a78d2b77e35be1e2", "title": "Henry Krum.", "abstract": null, "year": 2016, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          120\n        ", "volume": "387 10014"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673615013628/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "97740609", "name": "Alison Snyder"}], "url": "https://www.semanticscholar.org/paper/29c8bcadb286d32c77365551a78d2b77e35be1e2", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "1a5b420012fa74fb8e83af69218eb6c6a670e463", "title": "Quantifying the social impact of research and medical journals.", "abstract": null, "year": 2014, "publicationDate": null, "publicationTypes": ["Editorial"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          557\n        ", "volume": "384 9943"}, "citationCount": 3, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673614613490/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Sociology", "source": "s2-fos-model"}], "authors": [{"authorId": "67187695", "name": "The Lancet"}], "url": "https://www.semanticscholar.org/paper/1a5b420012fa74fb8e83af69218eb6c6a670e463", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "55e36c4fee70e76870795d7264c14e262b13bb66", "title": "Statins: friend or foe?", "abstract": null, "year": 2004, "publicationDate": "2004-08-27", "publicationTypes": [], "venue": "The Lancet", "journal": {"name": "The Lancet", "volume": "364"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673604168761/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "35112839", "name": "D. Carvalho"}], "url": "https://www.semanticscholar.org/paper/55e36c4fee70e76870795d7264c14e262b13bb66", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "bf17e5bed4d607ec5a3304139ea9b0d67c831cc0", "title": "Lipoprotein(a) and cardiovascular disease.", "abstract": "One in five people are at high risk for atherosclerotic cardiovascular disease and aortic valve stenosis due to high lipoprotein(a). Lipoprotein(a) concentrations are lowest in people from east Asia, Europe, and southeast Asia, intermediate in people from south Asia, the Middle East, and Latin America, and highest in people from Africa. Concentrations are more than 90% genetically determined and 17% higher in post-menopausal women than in men. Individuals at a higher cardiovascular risk should have lipoprotein(a) concentrations measured once in their lifetime to inform those with high concentrations to adhere to a healthy lifestyle and receive medication to lower other cardiovascular risk factors. With no approved drugs to lower lipoprotein(a) concentrations, it is promising that at least five drugs in development lower concentrations by 65-98%, with three currently being tested in large cardiovascular endpoint trials. This Review covers historical perspectives, physiology and pathophysiology, genetic evidence of causality, epidemiology, role in familial hypercholesterolaemia and diabetes, management, screening, diagnosis, measurement, prevention, and future lipoprotein(a)-lowering drugs.", "year": 2024, "publicationDate": "2024-09-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 164, "referenceCount": 125, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2267980079", "name": "B. Nordestgaard"}, {"authorId": "7252018", "name": "A. Langsted"}], "url": "https://www.semanticscholar.org/paper/bf17e5bed4d607ec5a3304139ea9b0d67c831cc0", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "983e26bb1d51301682afe35b9a39a6b9db6086ca", "title": "Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease (The Oxford Risk Factors And Non-invasive imaging study): A multicentre, longitudinal cohort study", "abstract": "SUMMARY Background: Coronary computed tomography angiography (CCTA) is the first line investigation for chest pain, and it is used to guide revascularisation. However, the widespread adoption of CCTA has revealed a large group of individuals without obstructive coronary artery disease (CAD), with unclear prognosis and management. Measurement of coronary inflammation from CCTA using perivascular fat attenuation index (FAI) Score could enable cardiovascular risk prediction and guide the management of individuals without obstructive CAD. Methods: Consecutive patients undergoing clinically indicated CCTA in 8 UK hospitals (n=40,091) were followed for Major Adverse Cardiac Events (MACE; myocardial infarction, new onset heart failure, or cardiac death) for a median(IQR) of 2·7(1·4–5·3)years. The prognostic value of FAI Score in the presence and absence of obstructive CAD was evaluated in 3,393 consecutive patients from the 2 hospitals with the longest follow up [7·7(6·4–9·1)years]. An artificial intelligence-enhanced cardiac risk prediction algorithm (AI-Risk), that integrates FAI Score, coronary plaque metrics and clinical risk factors, was then evaluated in this population. Findings: Patients without obstructive CAD (n=32,533, 81·1%) accounted for 66·3% (n=2,857) of MACE and 63·7% (n=1,118) of cardiac deaths during follow up. Increased FAI Score in all the three coronary arteries had an additive impact on the risk for cardiac mortality (HR 29∙8, 95% CI 13∙9–63∙0, P<0.001) or MACE (HR 12∙6, 95% CI 8∙5–18∙6, p<0.001) comparing 3 vessels with FAI Score in the top versus bottom quartile for each artery. FAI Score in any coronary artery predicted cardiac mortality and MACE independently from cardiovascular risk factors and the presence/extent of CAD. The AI-Risk classification was positively associated with cardiac mortality (HR 6∙75, 95% CI 5∙17–8∙82, p<0∙001, for very high vs low/medium risk) and MACE (HR 4∙68, 95% CI 3∙93–5∙57, p<0∙001 for very high vs low/medium risk). Finally, the AI-Risk model was well calibrated against true events. Interpretation: FAI Score captures inflammatory risk beyond the current clinical risk stratification and CCTA interpretation, particularly among patients without obstructive CAD. The AI-Risk integrates this information in a prognostic algorithm, that could be used as an alternative to traditional risk factors-based risk calculators.", "year": 2024, "publicationDate": "2024-05-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "2606 - 2618", "volume": "403"}, "citationCount": 168, "referenceCount": 29, "influentialCitationCount": 8, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/s0140-6736(24)00596-8", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2244739112", "name": "Kenneth Chan"}, {"authorId": "2275412219", "name": "Elizabeth Wahome"}, {"authorId": "6164345", "name": "A. Tsiachristas"}, {"authorId": "153315376", "name": "A. Antonopoulos"}, {"authorId": "2266464299", "name": "P. Patel"}, {"authorId": "1380568283", "name": "M. Lyasheva"}, {"authorId": "2035053846", "name": "L. Kingham"}, {"authorId": "2247531617", "name": "H. West"}, {"authorId": "9899196", "name": "E. Oikonomou"}, {"authorId": "2168264478", "name": "L. Volpe"}, {"authorId": "50591027", "name": "M. C. Mavrogiannis"}, {"authorId": "2275301845", "name": "E. Nicol"}, {"authorId": "2251138307", "name": "Tarun K. Mittal"}, {"authorId": "2218982030", "name": "T. Halborg"}, {"authorId": "12252247", "name": "R. Kotronias"}, {"authorId": "1576982144", "name": "D. Adlam"}, {"authorId": "2293913245", "name": "Bhavik Modi"}, {"authorId": "2068020797", "name": "J. Rodrigues"}, {"authorId": "2238449932", "name": "N. Screaton"}, {"authorId": "2240782455", "name": "Attila Kardos"}, {"authorId": "2250345976", "name": "J. Greenwood"}, {"authorId": "6302282", "name": "N. Sabharwal"}, {"authorId": "1757679", "name": "G. D. De Maria"}, {"authorId": "2271783270", "name": "S. Munir"}, {"authorId": "5859507", "name": "E. McAlindon"}, {"authorId": "2303675781", "name": "Yogesh Sohan"}, {"authorId": "2176921069", "name": "P. Tomlins"}, {"authorId": "2242738865", "name": "M. Siddique"}, {"authorId": "2418051", "name": "A. Kelion"}, {"authorId": "5447189", "name": "C. Shirodaria"}, {"authorId": "143720590", "name": "F. Pugliese"}, {"authorId": "2242129511", "name": "S. Petersen"}, {"authorId": "2238022001", "name": "R. Blankstein"}, {"authorId": "2296833421", "name": "M. Desai"}, {"authorId": "2244895509", "name": "B. J. Gersh"}, {"authorId": "2251739373", "name": "Stephan Achenbach"}, {"authorId": "2237583194", "name": "Peter Libby"}, {"authorId": "2298114196", "name": "Stefan Neubauer"}, {"authorId": "2260535119", "name": "K. Channon"}, {"authorId": "2254523667", "name": "J. Deanfield"}, {"authorId": "2185921046", "name": "Charalambos Antoniades"}], "url": "https://www.semanticscholar.org/paper/983e26bb1d51301682afe35b9a39a6b9db6086ca", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "e5a779f13d3be589ebcd83f1f90b1865c2310548", "title": "The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030.", "abstract": "Cardiovascular disease is the leading cause of death in women. Decades of grassroots campaigns have helped to raise awareness about the impact of cardiovascular disease in women, and positive changes affecting women and their health have gained momentum. Despite these efforts, there has been stagnation in the overall reduction of cardiovascular disease burden for women in the past decade. Cardiovascular disease in women remains understudied, under-recognised, underdiagnosed, and undertreated. This Commission summarises existing evidence and identifies knowledge gaps in research, prevention, treatment, and access to care for women. Recommendations from an international team of experts and leaders in the field have been generated with a clear focus to reduce the global burden of cardiovascular disease in women by 2030. This Commission represents the first effort of its kind to connect stakeholders, to ignite global awareness of sex-related and gender-related disparities in cardiovascular disease, and to provide a springboard for future research.", "year": 2021, "publicationDate": "2021-05-14", "publicationTypes": ["Review", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 1054, "referenceCount": 528, "influentialCitationCount": 55, "isOpenAccess": true, "openAccessPdfUrl": "https://ruj.uj.edu.pl/xmlui/handle/item/278340", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1773961", "name": "B. Vogel"}, {"authorId": "1689806", "name": "M. Acevedo"}, {"authorId": "4198933", "name": "Y. Appelman"}, {"authorId": "2243650947", "name": "C. N. Bairey Merz"}, {"authorId": "4770375", "name": "A. Chieffo"}, {"authorId": "1897829", "name": "G. Figtree"}, {"authorId": "143707193", "name": "M. Guerrero"}, {"authorId": "52212591", "name": "V. Kunadian"}, {"authorId": "48981366", "name": "C. Lam"}, {"authorId": "122920905", "name": "A. Maas"}, {"authorId": "5691079", "name": "A. Mihailidou"}, {"authorId": "8317088", "name": "A. Olszanecka"}, {"authorId": "35174378", "name": "J. Poole"}, {"authorId": "13821472", "name": "C. Saldarriaga"}, {"authorId": "2686338", "name": "J. Saw"}, {"authorId": "31801777", "name": "L. Zühlke"}, {"authorId": "1727907", "name": "R. Mehran"}], "url": "https://www.semanticscholar.org/paper/e5a779f13d3be589ebcd83f1f90b1865c2310548", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "23c0be28ac6e4713e6eb7e229a79e37350988713", "title": "Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention versus usual care on cardiovascular disease (CRHCP): an open-label, blinded-endpoint, cluster-randomised trial.", "abstract": "BACKGROUND\nEffectiveness of a non-physician community health-care provider-led intensive blood pressure intervention on cardiovascular disease has not been established. We aimed to test the effectiveness of such an intervention compared with usual care on risk of cardiovascular disease and all-cause death among individuals with hypertension.\n\n\nMETHODS\nIn this open-label, blinded-endpoint, cluster-randomised trial, we recruited individuals aged at least 40 years with an untreated systolic blood pressure of at least 140 mm Hg or a diastolic blood pressure of at least 90 mm Hg (≥130 mm Hg and ≥80 mm Hg for those at high risk for cardiovascular disease or if currently taking antihypertensive medication). We randomly assigned (1:1) 326 villages to a non-physician community health-care provider-led intervention or usual care, stratified by provinces, counties, and townships. In the intervention group, trained non-physician community health-care providers initiated and titrated antihypertensive medications according to a simple stepped-care protocol to achieve a systolic blood pressure goal of less than 130 mm Hg and diastolic blood pressure goal of less than 80 mm Hg with supervision from primary care physicians. They also delivered discounted or free antihypertensive medications and health coaching for patients. The primary effectiveness outcome was a composite outcome of myocardial infarction, stroke, heart failure requiring hospitalisation, and cardiovascular disease death during the 36-month follow-up in the study participants. Safety was assessed every 6 months. This trial is registered with ClinicalTrials.gov, NCT03527719.\n\n\nFINDINGS\nBetween May 8 and Nov 28, 2018, we enrolled 163 villages per group with 33 995 participants. Over 36 months, the net group difference in systolic blood pressure reduction was -23·1 mm Hg (95% CI -24·4 to -21·9; p<0·0001) and in diastolic blood pressure reduction, it was -9·9 mm Hg (-10·6 to -9·3; p<0·0001). Fewer patients in the intervention group than the usual care group had a primary outcome (1·62% vs 2·40% per year; hazard ratio [HR] 0·67, 95% CI 0·61-0·73; p<0·0001). Secondary outcomes were also reduced in the intervention group: myocardial infarction (HR 0·77, 95% CI 0·60-0·98; p=0·037), stroke (0·66, 0·60-0·73; p<0·0001), heart failure (0·58, 0·42-0·81; p=0·0016), cardiovascular disease death (0·70, 0·58-0·83; p<0·0001), and all-cause death (0·85, 0·76-0·95; p=0·0037). The risk reduction of the primary outcome was consistent across subgroups of age, sex, education, antihypertensive medication use, and baseline cardiovascular disease risk. Hypotension was higher in the intervention than in the usual care group (1·75% vs 0·89%; p<0·0001).\n\n\nINTERPRETATION\nThe non-physician community health-care provider-led intensive blood pressure intervention is effective in reducing cardiovascular disease and death.\n\n\nFUNDING\nThe Ministry of Science and Technology of China and the Science and Technology Program of Liaoning Province, China.", "year": 2023, "publicationDate": "2023-03-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 104, "referenceCount": 34, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2153098043", "name": "Jiang He"}, {"authorId": "2047624262", "name": "Nanxiang Ouyang"}, {"authorId": "8395486", "name": "Xiaofan Guo"}, {"authorId": "36045969", "name": "Guozhe Sun"}, {"authorId": "2156264511", "name": "Zhao Li"}, {"authorId": "47797873", "name": "J. Mu"}, {"authorId": "2116474648", "name": "D. Wang"}, {"authorId": "2163788889", "name": "Lixia Qiao"}, {"authorId": "2625760", "name": "L. Xing"}, {"authorId": "2055939229", "name": "Guocheng Ren"}, {"authorId": "145838427", "name": "Chunxia Zhao"}, {"authorId": "3033433", "name": "Rui-hai Yang"}, {"authorId": "144675840", "name": "Zuyi Yuan"}, {"authorId": "2146410609", "name": "Chang Wang"}, {"authorId": "2113917225", "name": "Chuning Shi"}, {"authorId": "2044675829", "name": "Songyue Liu"}, {"authorId": "2105518979", "name": "W. Miao"}, {"authorId": "2151299792", "name": "Guangxiao Li"}, {"authorId": "1415428087", "name": "Chung-Shiuan Chen"}, {"authorId": "2145323695", "name": "Yingxian Sun"}, {"authorId": "46447910", "name": "Xingang Zhang"}, {"authorId": "2152810139", "name": "Jun Wang"}, {"authorId": "2118860592", "name": "Ying Zhou"}, {"authorId": "145361605", "name": "Ning Ye"}, {"authorId": "2144251424", "name": "Zihan Chen"}, {"authorId": "40627027", "name": "Pengyu Zhang"}, {"authorId": "2113846875", "name": "Zihao Fan"}, {"authorId": "2066092963", "name": "Nan Ye"}, {"authorId": "2107956824", "name": "Linlin Zhang"}, {"authorId": "2044769169", "name": "D. Geng"}, {"authorId": "2118372368", "name": "Shu Zhang"}, {"authorId": "2375698876", "name": "Qiyu Li"}, {"authorId": "2066430585", "name": "Qi Qin"}, {"authorId": "2164277503", "name": "Canru Liu"}, {"authorId": "2152198264", "name": "Xiaoyu Zheng"}, {"authorId": "2156631896", "name": "Tao Wang"}, {"authorId": "88586664", "name": "L. Jing"}, {"authorId": "2404679505", "name": "Boqiang Zhang"}, {"authorId": "2112489851", "name": "Qun Sun"}, {"authorId": "1390715132", "name": "Yu Yan"}, {"authorId": "122565026", "name": "Yueyuan Liao"}, {"authorId": "47428485", "name": "Qiong Ma"}, {"authorId": "2745971", "name": "C. Chu"}, {"authorId": "2116970135", "name": "Yue Sun"}, {"authorId": "2155681638", "name": "Dan Wang"}, {"authorId": "2122829250", "name": "Ling Zhou"}, {"authorId": "1384701010", "name": "H. Ye"}, {"authorId": "2109395283", "name": "Haoran Wei"}, {"authorId": "48446759", "name": "H. Liu"}, {"authorId": "5385862", "name": "Zhaoqing Sun"}, {"authorId": "144524823", "name": "Liqiang Zheng"}, {"authorId": "2109266214", "name": "Yanli Chen"}, {"authorId": "2309003", "name": "Ye Chang"}, {"authorId": "12975011", "name": "Mohan Jiang"}, {"authorId": "47912652", "name": "Hong-mei Yang"}, {"authorId": "5946098", "name": "Shasha Yu"}, {"authorId": "3193186", "name": "Wenna Li"}, {"authorId": "2152171621", "name": "Ning Wang"}, {"authorId": null, "name": "Chunwei Wu"}, {"authorId": "41191181", "name": "Lufan Sun"}, {"authorId": "115195528", "name": "Z. Du"}, {"authorId": "2152884281", "name": "Yan Li"}, {"authorId": "2068203935", "name": "N. Gao"}, {"authorId": "2157356780", "name": "Xinchi Liu"}, {"authorId": "2155515986", "name": "Ying Wang"}, {"authorId": "117337202", "name": "Ming-Shang Huang"}, {"authorId": "2390033040", "name": "Yufang Zhou"}, {"authorId": "2113609786", "name": "L. Meng"}, {"authorId": "2107988137", "name": "Jiawen Zhang"}, {"authorId": "2151326219", "name": "Zhen Huang"}, {"authorId": "2155553694", "name": "Huihui Chen"}, {"authorId": "121240997", "name": "Yuxian Huang"}, {"authorId": "2145125717", "name": "L. Sun"}, {"authorId": "2113309833", "name": "Xin Zhong"}, {"authorId": "2113291724", "name": "Hanmin Wang"}, {"authorId": "48624649", "name": "Xinyan Hou"}, {"authorId": "2112488125", "name": "Huan Han"}, {"authorId": "2057048949", "name": "B. Jin"}, {"authorId": "2182982234", "name": "Huan He"}], "url": "https://www.semanticscholar.org/paper/23c0be28ac6e4713e6eb7e229a79e37350988713", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "35c15c1d9f560708020e9fb6d9d9646c1d35dc9a", "title": "Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial.", "abstract": "BACKGROUND\nMediterranean and low-fat diets are effective in the primary prevention of cardiovascular disease. We did a long-term randomised trial to compare the effects of these two diets in secondary prevention of cardiovascular disease.\n\n\nMETHODS\nThe CORDIOPREV study was a single-centre, randomised clinical trial done at the Reina Sofia University Hospital in Córdoba, Spain. Patients with established coronary heart disease (aged 20-75 years) were randomly assigned in a 1:1 ratio by the Andalusian School of Public Health to receive a Mediterranean diet or a low-fat diet intervention, with a follow-up of 7 years. Clinical investigators (physicians, investigators, and clinical endpoint committee members) were masked to treatment assignment; participants were not. A team of dietitians did the dietary interventions. The primary outcome (assessed by intention to treat) was a composite of major cardiovascular events, including myocardial infarction, revascularisation, ischaemic stroke, peripheral artery disease, and cardiovascular death. This study is registered with ClinicalTrials.gov, NCT00924937.\n\n\nFINDINGS\nFrom Oct 1, 2009, to Feb 28, 2012, a total of 1002 patients were enrolled, 500 (49·9%) in the low-fat diet group and 502 (50·1%) in the Mediterranean diet group. The mean age was 59·5 years (SD 8·7) and 827 (82·5%) of 1002 patients were men. The primary endpoint occurred in 198 participants: 87 in the Mediterranean diet group and 111 in the low-fat group (crude rate per 1000 person-years: 28·1 [95% CI 27·9-28·3] in the Mediterranean diet group vs 37·7 [37·5-37·9] in the low-fat group, log-rank p=0·039). Multivariable-adjusted hazard ratios (HRs) of the different models ranged from 0·719 (95% CI 0·541-0·957) to 0·753 (0·568-0·998) in favour of the Mediterranean diet. These effects were more evident in men, with primary endpoints occurring in 67 (16·2%) of 414 men in the Mediterranean diet group versus 94 (22·8%) of 413 men in the low-fat diet group (multiadjusted HR 0·669 [95% CI 0·489-0·915], log-rank p=0·013), than in 175 women for whom no difference was found between groups.\n\n\nINTERPRETATION\nIn secondary prevention, the Mediterranean diet was superior to the low-fat diet in preventing major cardiovascular events. Our results are relevant to clinical practice, supporting the use of the Mediterranean diet in secondary prevention.\n\n\nFUNDING\nFundacion Patrimonio Comunal Olivarero; Fundacion Centro para la Excelencia en Investigacion sobre Aceite de Oliva y Salud; local, regional, and national Spanish Governments; European Union.", "year": 2022, "publicationDate": "2022-05-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 441, "referenceCount": 37, "influentialCitationCount": 16, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1397905891", "name": "J. Delgado-Lista"}, {"authorId": "1401212094", "name": "J. Alcalá-Díaz"}, {"authorId": "1403460769", "name": "J. Torres-Peña"}, {"authorId": "1398546687", "name": "G. Quintana-Navarro"}, {"authorId": "3136828", "name": "F. Fuentes"}, {"authorId": "1398896044", "name": "A. García-Rios"}, {"authorId": "1402127921", "name": "A. Ortiz-Morales"}, {"authorId": "1435236163", "name": "A. Gonzalez-Requero"}, {"authorId": "1398896023", "name": "Ana I. Perez-Caballero"}, {"authorId": "1401090876", "name": "E. Yubero-Serrano"}, {"authorId": "1398546719", "name": "O. Rangel-Zúñiga"}, {"authorId": "144737987", "name": "A. Camargo"}, {"authorId": "1398896028", "name": "F. Rodríguez-Cantalejo"}, {"authorId": "82091449", "name": "F. López-Segura"}, {"authorId": "143820905", "name": "L. Badimón"}, {"authorId": "2369121", "name": "J. Ordovás"}, {"authorId": "1398546709", "name": "F. Perez-Jimenez"}, {"authorId": "1421889418", "name": "P. Pérez-Martínez"}, {"authorId": "83102709", "name": "J. López-Miranda"}], "url": "https://www.semanticscholar.org/paper/35c15c1d9f560708020e9fb6d9d9646c1d35dc9a", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "ce59d3bd377b7a526379abe53327f84ff82cd83a", "title": "Performance of cardiovascular disease risk prediction equations in more than 14 000 survivors of cancer in New Zealand primary care: a validation study.", "abstract": "BACKGROUND\nPeople with cancer have an increased risk of cardiovascular disease. Risk prediction equations developed in New Zealand accurately predict 5-year cardiovascular disease risk in a general primary care population in the country. We assessed the performance of these equations for survivors of cancer in New Zealand.\n\n\nMETHODS\nFor this validation study, patients aged 30-74 years from the PREDICT open cohort study, which was used to develop the New Zealand cardiovascular disease risk prediction equations, were included in the analysis if they had a primary diagnosis of invasive cancer at least 2 years before the date of the first cardiovascular disease risk assessment. The risk prediction equations are sex-specific and include the following predictors: age, ethnicity, socioeconomic deprivation index, family history of cardiovascular disease, smoking status, history of atrial fibrillation and diabetes, systolic blood pressure, total cholesterol to HDL cholesterol ratio, and preventive pharmacotherapy (blood-pressure-lowering, lipid-lowering, and antithrombotic drugs). Calibration was assessed by comparing the mean predicted 5-year cardiovascular disease risk, estimated using the risk prediction equations, with the observed risk across deciles of risk, for men and women, and according to the three clinical 5-year cardiovascular disease risk groups in New Zealand guidelines (<5%, 5% to <15%, and ≥15%). Discrimination was assessed by Harrell's C statistic.\n\n\nFINDINGS\n14 263 patients were included in the study. The mean age was 61 years (SD 9) for men and 60 years (SD 8) for women, with a median follow-up of 5·8 years for men and 5·7 years for women. The observed cardiovascular disease risk was underpredicted by a maximum of 2·5% in male and 3·2% in female decile groups. When patients were grouped according to clinical risk groups, observed cardiovascular disease risk was underpredicted by less than 2% in the lower risk groups and overpredicted by 2·2% for men and 3·3% for women in the highest risk group. Harrell's C statistics were 0·67 (SE 0·01) for men and 0·73 (0·01) for women.\n\n\nINTERPRETATION\nThe New Zealand cardiovascular disease risk prediction equations reasonably predicted the observed 5-year cardiovascular disease risk in survivors of cancer in the country, in whom risk prediction was considered clinically appropriate. Prediction could be improved by adding cancer-specific variables and considering competing risks. Our findings suggest that the equations are reasonable clinical tools for use in survivors of cancer in New Zealand.\n\n\nFUNDING\nAuckland Medical Research Foundation, Health Research Council of New Zealand.", "year": 2023, "publicationDate": "2023-01-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 21, "referenceCount": 23, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "29403222", "name": "Essa Tawfiq"}, {"authorId": "4830060", "name": "V. Selak"}, {"authorId": "1398428123", "name": "J. M. Elwood"}, {"authorId": "5309969", "name": "R. Pylypchuk"}, {"authorId": "47541823", "name": "S. Tin"}, {"authorId": "48720739", "name": "M. Harwood"}, {"authorId": "48938382", "name": "C. Grey"}, {"authorId": "3842087", "name": "M. McKeage"}, {"authorId": "73774267", "name": "S. Wells"}], "url": "https://www.semanticscholar.org/paper/ce59d3bd377b7a526379abe53327f84ff82cd83a", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "370a714fdfc8fc5a192ab6bb3275dfd877cec486", "title": "Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis", "abstract": "Summary Background The effects of pharmacological blood pressure lowering at normal or high-normal blood pressure ranges in people with or without pre-existing cardiovascular disease remains uncertain. We analysed individual participant data from randomised trials to investigate the effects of blood pressure lowering treatment on the risk of major cardiovascular events by baseline levels of systolic blood pressure. Methods We did a meta-analysis of individual participant-level data from 48 randomised trials of pharmacological blood pressure lowering medications versus placebo or other classes of blood pressure-lowering medications, or between more versus less intensive treatment regimens, which had at least 1000 persons-years of follow-up in each group. Trials exclusively done with participants with heart failure or short-term interventions in participants with acute myocardial infarction or other acute settings were excluded. Data from 51 studies published between 1972 and 2013 were obtained by the Blood Pressure Lowering Treatment Trialists' Collaboration (Oxford University, Oxford, UK). We pooled the data to investigate the stratified effects of blood pressure-lowering treatment in participants with and without prevalent cardiovascular disease (ie, any reports of stroke, myocardial infarction, or ischaemic heart disease before randomisation), overall and across seven systolic blood pressure categories (ranging from <120 to ≥170 mm Hg). The primary outcome was a major cardiovascular event (defined as a composite of fatal and non-fatal stroke, fatal or non-fatal myocardial infarction or ischaemic heart disease, or heart failure causing death or requiring admission to hospital), analysed as per intention to treat. Findings Data for 344 716 participants from 48 randomised clinical trials were available for this analysis. Pre-randomisation mean systolic/diastolic blood pressures were 146/84 mm Hg in participants with previous cardiovascular disease (n=157 728) and 157/89 mm Hg in participants without previous cardiovascular disease (n=186 988). There was substantial spread in participants' blood pressure at baseline, with 31 239 (19·8%) of participants with previous cardiovascular disease and 14 928 (8·0%) of individuals without previous cardiovascular disease having a systolic blood pressure of less than 130 mm Hg. The relative effects of blood pressure-lowering treatment were proportional to the intensity of systolic blood pressure reduction. After a median 4·15 years' follow-up (Q1–Q3 2·97–4·96), 42 324 participants (12·3%) had at least one major cardiovascular event. In participants without previous cardiovascular disease at baseline, the incidence rate for developing a major cardiovascular event per 1000 person-years was 31·9 (95% CI 31·3–32·5) in the comparator group and 25·9 (25·4–26·4) in the intervention group. In participants with previous cardiovascular disease at baseline, the corresponding rates were 39·7 (95% CI 39·0–40·5) and 36·0 (95% CI 35·3–36·7), in the comparator and intervention groups, respectively. Hazard ratios (HR) associated with a reduction of systolic blood pressure by 5 mm Hg for a major cardiovascular event were 0·91, 95% CI 0·89–0·94 for partipants without previous cardiovascular disease and 0·89, 0·86–0·92, for those with previous cardiovascular disease. In stratified analyses, there was no reliable evidence of heterogeneity of treatment effects on major cardiovascular events by baseline cardiovascular disease status or systolic blood pressure categories. Interpretation In this large-scale analysis of randomised trials, a 5 mm Hg reduction of systolic blood pressure reduced the risk of major cardiovascular events by about 10%, irrespective of previous diagnoses of cardiovascular disease, and even at normal or high–normal blood pressure values. These findings suggest that a fixed degree of pharmacological blood pressure lowering is similarly effective for primary and secondary prevention of major cardiovascular disease, even at blood pressure levels currently not considered for treatment. Physicians communicating the indication for blood pressure lowering treatment to their patients should emphasise its importance on reducing cardiovascular risk rather than focusing on blood pressure reduction itself. Funding British Heart Foundation, UK National Institute for Health Research, and Oxford Martin School.", "year": 2021, "publicationDate": "2021-05-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "1625 - 1636", "volume": "397"}, "citationCount": 626, "referenceCount": 47, "influentialCitationCount": 16, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673621005900/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": null, "name": "Amanda Larry Ale Folkert W Nigel S Eivind Henry Frank P J Adler Agodoa Algra Asselbergs Beckett Berge Black "}, {"authorId": "3639449", "name": "A. Adler"}, {"authorId": "34046547", "name": "L. Agodoa"}, {"authorId": "145486242", "name": "A. Algra"}, {"authorId": "39458739", "name": "F. Asselbergs"}, {"authorId": "4323309", "name": "N. Beckett"}, {"authorId": "113010352", "name": "E. Berge"}, {"authorId": "4474719", "name": "H. Black"}, {"authorId": "7889636", "name": "F. P. Brouwers"}, {"authorId": "152581899", "name": "Morris J. Brown"}, {"authorId": "143892455", "name": "C. Bulpitt"}, {"authorId": "81152256", "name": "R. Byington"}, {"authorId": "145973521", "name": "J. Chalmers"}, {"authorId": "6455627", "name": "W. Cushman"}, {"authorId": "1973126", "name": "J. Cutler"}, {"authorId": "39757654", "name": "B. Davis"}, {"authorId": "79582376", "name": "R. Devereaux"}, {"authorId": "2402475", "name": "J. Dwyer"}, {"authorId": "6925635", "name": "R. Estacio"}, {"authorId": "3856244", "name": "R. Fagard"}, {"authorId": "145048359", "name": "K. Fox"}, {"authorId": "3289886", "name": "T. Fukui"}, {"authorId": "2110020123", "name": "Ajay K. Gupta"}, {"authorId": "2317710", "name": "R. Holman"}, {"authorId": "32633461", "name": "Y. Imai"}, {"authorId": "1845200", "name": "M. Ishii"}, {"authorId": "2052439112", "name": "S. Julius"}, {"authorId": "3493975", "name": "Y. Kanno"}, {"authorId": "6213357", "name": "S. Kjeldsen"}, {"authorId": "6020227", "name": "J. Kostis"}, {"authorId": "1700550", "name": "K. Kuramoto"}, {"authorId": "4348490", "name": "J. Lanke"}, {"authorId": "2068825188", "name": "E. Lewis"}, {"authorId": "2109189895", "name": "J. Lewis"}, {"authorId": "143884449", "name": "M. Lièvre"}, {"authorId": "5278153", "name": "L. Lindholm"}, {"authorId": "144784042", "name": "S. Lueders"}, {"authorId": "48040733", "name": "S. MacMahon"}, {"authorId": "6478764", "name": "G. Mancia"}, {"authorId": "32500162", "name": "M. Matsuzaki"}, {"authorId": "14559133", "name": "M. Mehlum"}, {"authorId": "3844310", "name": "S. Nissen"}, {"authorId": "48145507", "name": "H. Ogawa"}, {"authorId": "2504477", "name": "T. Ogihara"}, {"authorId": "145022633", "name": "T. Ohkubo"}, {"authorId": "143613706", "name": "C. Palmer"}, {"authorId": "4138511", "name": "Anushka Patel"}, {"authorId": "5479974", "name": "C. Pepine"}, {"authorId": "145436306", "name": "M. Pfeffer"}, {"authorId": "144526806", "name": "B. Pitt"}, {"authorId": "6786258", "name": "N. Poulter"}, {"authorId": "5030920", "name": "H. Rakugi"}, {"authorId": "153839824", "name": "G. Reboldi"}, {"authorId": "2052732422", "name": "C. Reid"}, {"authorId": "8390357", "name": "G. Remuzzi"}, {"authorId": "2867767", "name": "P. Ruggenenti"}, {"authorId": "4356295", "name": "T. Saruta"}, {"authorId": "48277778", "name": "J. Schrader"}, {"authorId": "2737121", "name": "R. Schrier"}, {"authorId": "26925714", "name": "P. Sever"}, {"authorId": "4797329", "name": "P. Sleight"}, {"authorId": "47149250", "name": "J. Staessen"}, {"authorId": "2111603801", "name": "Hiromichi Suzuki"}, {"authorId": "5265019", "name": "L. Thijs"}, {"authorId": "6916138", "name": "K. Ueshima"}, {"authorId": "5510813", "name": "S. Umemoto"}, {"authorId": "5896382", "name": "W. V. van Gilst"}, {"authorId": "4463638", "name": "P. Verdecchia"}, {"authorId": "3737835", "name": "K. Wachtell"}, {"authorId": "6352525", "name": "P. Whelton"}, {"authorId": "2268042", "name": "L. Wing"}, {"authorId": "145037492", "name": "M. Woodward"}, {"authorId": "2109254", "name": "Y. Yui"}, {"authorId": "113666777", "name": "S. Yusuf"}, {"authorId": "3559625", "name": "A. Zanchetti"}, {"authorId": "50316136", "name": "Zhenyu Zhang"}, {"authorId": "145589412", "name": "C. Anderson"}, {"authorId": "5278382", "name": "C. Baigent"}, {"authorId": "4001102", "name": "B. Brenner"}, {"authorId": "2412365719", "name": "R. Collins"}, {"authorId": "80518345", "name": "D. de Zeeuw"}, {"authorId": "6644958", "name": "J. Lubsen"}, {"authorId": "7349028", "name": "E. Malacco"}, {"authorId": "145259700", "name": "B. Neal"}, {"authorId": "4409983", "name": "V. Perkovic"}, {"authorId": "145188451", "name": "A. Rodgers"}, {"authorId": "3981432", "name": "P. Rothwell"}, {"authorId": "1402005227", "name": "G. Salimi-Khorshidi"}, {"authorId": "144023638", "name": "J. Sundström"}, {"authorId": "3659160", "name": "F. Turnbull"}, {"authorId": "32127108", "name": "G. Viberti"}, {"authorId": "2110139568", "name": "Jiguang Wang"}], "url": "https://www.semanticscholar.org/paper/370a714fdfc8fc5a192ab6bb3275dfd877cec486", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "23ed4f510828cf7b929823c3848ef775f0af0eda", "title": "Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER) in the UK: a cluster-randomised controlled implementation trial.", "abstract": "BACKGROUND\nEarly detection of cardiovascular disease is a global public health priority. Artificial intelligence (AI)-enabled stethoscopes offer robust performance characteristics in point-of-care detection of heart failure, atrial fibrillation, and valvular heart disease (VHD). We conducted a pragmatic, cluster-randomised controlled implementation trial to determine the real-world effect and implementation challenges of AI-stethoscopes.\n\n\nMETHODS\nUK primary care practices were cluster randomised 1:1 to intervention (training and implementation in use of AI-stethoscopes in routine care) or control (routine care). Given the nature of the intervention, masking of participants (practices, clinicians, and patients) was not feasible. During cardiac examinations, the AI stethoscope recorded 15 s of single-lead electrocardiogram and phonocardiogram signals for input to three AI algorithms that returned binary predictions for the presence or absence of reduced left ventricular ejection fraction (≤40%), atrial fibrillation, and VHD (all with regulatory approval). The primary endpoint was incidence of any newly coded diagnosis of heart failure (all subtypes), expressed per 1000 patient-years (incidence rate ratio [IRR]), derived from a UK National Health Service Secure Data Environment. A coprimary endpoint stratified detection of heart failure by place of diagnosis (community-based vs via hospital admission). Secondary endpoints included atrial fibrillation and VHD detection rates, performance characteristics of the AI-stethoscope, use rates, and clinician-reported implementation barriers and enablers.\n\n\nFINDINGS\nBetween Oct 30, 2023, and May 22, 2024, 205 practices were randomly assigned (96 to the intervention arm [701 933 registered patients] and 109 to the control arm [851 242 registered patients]). Intervention practices recorded 12 725 patient examinations with the AI-stethoscope, across 972 clinical users. Intention-to-treat analysis found heart failure detection did not differ between groups (IRR 0·94 [95% CI 0·86-1·02]); with no difference in community-based or hospital-based diagnoses (p>0·05).\n\n\nINTERPRETATION\nImplementation of an AI stethoscope in routine primary care did not significantly increase detection of heart failure or increase community-based diagnosis after 12 months of implementation. AI stethoscope use was independently associated with significantly higher detection rates of heart failure, as well as atrial fibrillation and VHD. This randomised controlled implementation trial establishes a pragmatic design with randomisation that generates real-world data essential for understanding and overcoming the barriers to implementation of innovation in health care.\n\n\nFUNDING\nNational Institute for Health and Care Research, British Heart Foundation, and Imperial Health Charity.", "year": 2026, "publicationDate": "2026-01-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 14, "referenceCount": 44, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(25)02156-7.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "6115881", "name": "M. Kelshiker"}, {"authorId": "2362568363", "name": "Patrik Bächtiger"}, {"authorId": "2362568628", "name": "C. Petri"}, {"authorId": "2362567748", "name": "S. Nakhare"}, {"authorId": "2328152032", "name": "J. Mansell"}, {"authorId": "2328151068", "name": "K. Chhatwal"}, {"authorId": "2295038867", "name": "A. Alrumayh"}, {"authorId": "2407597152", "name": "J. Zaman"}, {"authorId": "2211844872", "name": "Moulesh Shah"}, {"authorId": "2407560515", "name": "H. Young"}, {"authorId": "2097983686", "name": "H. Roy"}, {"authorId": "2328202221", "name": "M. Almonte"}, {"authorId": "1517851271", "name": "C. Costelloe"}, {"authorId": "2401905390", "name": "Y. Razak"}, {"authorId": "2265435098", "name": "A. Majeed"}, {"authorId": "2266266890", "name": "J. P. Howard"}, {"authorId": "2349835057", "name": "C. Barton"}, {"authorId": "2407599999", "name": "D. B. Kramer"}, {"authorId": "2328206758", "name": "C. Plymen"}, {"authorId": "2303510159", "name": "N. S. Peters"}], "url": "https://www.semanticscholar.org/paper/23ed4f510828cf7b929823c3848ef775f0af0eda", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "cf113eb0731b63f80348e5bc3ce44e58f1e1a678", "title": "Pharmacological blood-pressure lowering for the prevention of cardiovascular disease and death across the full spectrum of chronic kidney disease severity: an individual-participant data meta-analysis.", "abstract": "BACKGROUND\nIndividuals with chronic kidney disease (CKD), particularly those at more advanced stages, have been systematically under-represented in randomised controlled trials (RCTs) of blood-pressure-lowering treatment due to safety concerns, leading to a persistent paucity of evidence for cardiovascular risk management in this high-risk group. We investigated the effect of blood-pressure-lowering treatment on the risk of major cardiovascular disease and death across the full spectrum of CKD stages and by key clinical subgroups.\n\n\nMETHODS\nWe conducted a one-stage meta-analysis of individual-participant data from RCTs in which participants were randomly assigned to a blood-pressure-lowering therapy versus a comparator. We used RCTs collated in the Blood Pressure Lowering Treatment Trialists' Collaboration dataset, published at any time in any language, which were eligible for inclusion if they had at least 1000 person-years of follow-up per arm, baseline blood-pressure and creatinine measurements, and time-to-event outcomes; those with unclear randomisation procedures or restricted to heart failure or acute care settings were excluded. Participants with a documented history of heart failure or extreme creatinine values were excluded. No age criteria were applied. The primary outcome was major cardiovascular events, defined as a composite of fatal or non-fatal stroke, ischaemic heart disease, or hospitalisation for, or death from, heart failure. Relative treatment effects were estimated with a stratified Cox proportional hazards model. Heterogeneity of treatment effects was evaluated across prespecified subgroups defined by CKD status, CKD stage (1-5), diabetes, proteinuria, and baseline blood pressure. A stratified network meta-analysis was performed to examine whether treatment effects differed by defined subgroups within each of five principal antihypertensive drug classes. The systematic review was registered in PROSPERO (CRD42018099283).\n\n\nFINDINGS\nFrom 52 RCTs (363 684 participants), a total of 285 124 participants from 46 randomised trials met the eligibility criteria; 116 145 (40·7%) were women, 168 979 (59·3%) were men, 59 185 (20·7%) had CKD at baseline, and 86 067 (30·2%) had type 2 diabetes. During a median follow-up of 4·4 years (IQR 3·2-5·1), a 5 mm Hg reduction in systolic blood pressure reduced the risk of major cardiovascular disease in individuals with CKD (hazard ratio [HR] 0·91 [95% CI 0·87-0·94]) and without CKD (0·90 [0·88-0·93]; pinteraction>0·99). Furthermore, these observed relative risk reductions were consistent across all CKD stages, including severe stages 4-5 (pinteraction>0·99). Similar treatment effects were observed by proteinuria status and across blood-pressure categories, down to <120/70 mm Hg. However, the relative treatment effect in individuals with CKD was notably attenuated among those with coexisting diabetes (HR 0·96 [95% CI 0·90-1·02]) compared with those without (0·88 [0·84-0·93]; pinteraction=0·044). The stratified analysis within each drug class showed that the class-specific effects of antihypertensive agents versus placebo on cardiovascular disease risk remained unchanged across the investigated subgroups.\n\n\nINTERPRETATION\nIn the context of cardiovascular risk reduction, the relative benefit of blood-pressure lowering in patients with CKD is similar to that in individuals without CKD, with consistent efficacy across all CKD stages, blood-pressure thresholds, and proteinuria status. However, notably, this relative benefit is attenuated in patients with CKD and concomitant diabetes, underscoring the requirement for adapted therapeutic strategies in this high-risk subgroup. Moreover, the class-specific effects of principal antihypertensives in CKD mirror those observed in the broader population, independent of CKD stage or proteinuria status.\n\n\nFUNDING\nBritish Heart Foundation.", "year": 2026, "publicationDate": "2026-04-01", "publicationTypes": ["MetaAnalysis", "JournalArticle", "Review"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1626-1638\n        ", "volume": "407 10539"}, "citationCount": 2, "referenceCount": 51, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/s0140-6736(26)00367-3", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2159501888", "name": "Guyu Zeng"}, {"authorId": "4703742", "name": "Z. Bidel"}, {"authorId": "2330396383", "name": "Qianqian Yang"}, {"authorId": "2250018941", "name": "D. Canoy"}, {"authorId": "2247441097", "name": "Mark Woodward"}, {"authorId": "2293312723", "name": "Julia B. Lewis"}, {"authorId": "2276372785", "name": "Sverre E. Kjeldsen"}, {"authorId": "2276980133", "name": "William C Cushman"}, {"authorId": "2240272005", "name": "Jinqing Yuan"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "2250031580", "name": "B. Davis"}, {"authorId": "2245080398", "name": "J. Chalmers"}, {"authorId": "2259964036", "name": "C. Pepine"}, {"authorId": "2308494351", "name": "Kazem Rahimi"}, {"authorId": "2409853", "name": "M. Nazarzadeh"}], "url": "https://www.semanticscholar.org/paper/cf113eb0731b63f80348e5bc3ce44e58f1e1a678", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "a1bc23abaeb985ad4e3fcdf53f5e8301a7674360", "title": "Factors affecting the delivery of community-based salon interventions to prevent cardiovascular disease and breast cancer among ethnically diverse women in South London: a concept-mapping approach.", "abstract": "BACKGROUND\nIn the UK, women from ethnically diverse and socioeconomically deprived communities are at increased risk of underdiagnosis of cardiovascular disease (CVD) and breast cancer. Promoting CVD prevention and awareness of breast cancer screening via community salons and primary health care partnerships can improve uptake of screening services and early detection.\n\n\nMETHODS\nConcept mapping is a multistage mixed methods participatory approach comprised of six stages: preparation, brainstorming, structuring of statements, representing statements, interpretation and utilisation of maps using Group wisdom software. A target of 20 salons, excluding male-only salons were approached. Salons included Salons included hairdressing or hairdressing and beauty salons. Purposeful and convenience sampling (online and face to face) among UK salons (hair and beauty) was conducted. Participants were given a focus prompt \"What would be some factors that can influence the ability of salons to deliver this service?\" and required to generate statements, which were sorted into categories based on similarity and rated for importance and feasibility. Concept maps using multidimensional scaling and hierarchical cluster analyses were produced.\n\n\nFINDINGS\nOf 35 participants invited, 25 (71%) consented and agreed to take part in concept mapping. Reported ages were 26-35 years (n=5, 20%), 36-45 years (n=12, 48%), 46-55 years (n=3, 12%), 56-65 years (n=5, 20%), and no age reported (n=10, 40%). Around 36% (n=9) of participants were from non-White ethnic groups, with 12% (n=3) being male and 88% (n=22) female. Seven clusters emerged. Salon staff capabilities and capacities and engaging in health conversations in community salons scored average bridging values of 0·09 and 0·2 respectively, indicating good cluster homogeneity (similar meaning statements were closely sorted). Facilitating health-care access with GP practices was rated highly important to effectively promote the intervention. Engaging in health conversations in community salons and salon incentives for participation were examples of factors that were highly feasible to address. The r correlation coefficient was 0·68 between importance and feasibility to address factors affecting community health interventions.\n\n\nINTERPRETATION\nSalons are well positioned to support health promotion interventions. Actionable priorities were identified for a salon-GP surgery partnership to promote CVD prevention through lifestyle changes and health check uptake, raising breast cancer screening awareness and address issue of equity.\n\n\nFUNDING\nNational Institute of Health and Care Research (NIHR), Research for Patient Benefit (RfPB) Programme NIHR202769.", "year": 2023, "publicationDate": "2023-11-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          S96\n        ", "volume": "402 Suppl 1"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Sociology", "source": "s2-fos-model"}], "authors": [{"authorId": "2267928583", "name": "Maham Zaman"}, {"authorId": "2224310586", "name": "Marjorie Lima de Vale"}, {"authorId": "2267927425", "name": "Clare Coultas"}, {"authorId": "2267930018", "name": "Louise M. Goff"}, {"authorId": "2224310633", "name": "Ashlyn Mernagh-iles"}, {"authorId": "1404322694", "name": "V. L'Esperance"}, {"authorId": "4886979", "name": "A. Karamanos"}, {"authorId": "2267928921", "name": "S. Ayis"}, {"authorId": "1778446", "name": "V. Curcin"}, {"authorId": "3925134", "name": "S. Durbaba"}, {"authorId": "2267929832", "name": "Muriel I. Inyang"}, {"authorId": "2241289061", "name": "M. Molokhia"}, {"authorId": "2056345672", "name": "S. Harding"}], "url": "https://www.semanticscholar.org/paper/a1bc23abaeb985ad4e3fcdf53f5e8301a7674360", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "ba7b42aab245ba583e1a7be6d401ff07dde9061f", "title": "Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial.", "abstract": "BACKGROUND\nDrug combinations rather than increasing doses of one drug can achieve greater efficacy and lower risks. Thus, as an alternative to high-intensity statin monotherapy, moderate-intensity statin with ezetimibe combination therapy can lower LDL cholesterol concentrations effectively while reducing adverse effects. However, evidence from randomised trials to compare long-term clinical outcomes is needed.\n\n\nMETHODS\nIn this randomised, open-label, non-inferiority trial, patients with atherosclerotic cardiovascular disease (ASCVD) at 26 clinical centres in South Korea were randomly assigned (1:1) to receive either moderate-intensity statin with ezetimibe combination therapy (rosuvastatin 10 mg with ezetimibe 10 mg) or high-intensity statin monotherapy (rosuvastatin 20 mg). The primary endpoint was the 3-year composite of cardiovascular death, major cardiovascular events, or non-fatal stroke, in the intention-to-treat population with a non-inferiority margin of 2·0%. This trial is registered with ClinicalTrials.gov, NCT03044665 and is complete.\n\n\nFINDINGS\nBetween Feb 14, 2017, and Dec 18, 2018, 3780 patients were enrolled: 1894 patients to the combination therapy group and 1886 to the high-intensity statin monotherapy group. The primary endpoint occurred in 172 patients (9·1%) in the combination therapy group and 186 patients (9·9%) in the high-intensity statin monotherapy group (absolute difference -0·78%; 90% CI -2·39 to 0·83). LDL cholesterol concentrations of less than 70 mg/dL at 1, 2, and 3 years were observed in 73%, 75%, and 72% of patients in the combination therapy group, and 55%, 60%, and 58% of patients in the high-intensity statin monotherapy group (all p<0·0001). Discontinuation or dose reduction of the study drug by intolerance was observed in 88 patients (4·8%) and 150 patients (8·2%), respectively (p<0·0001).\n\n\nINTERPRETATION\nAmong patients with ASCVD, moderate-intensity statin with ezetimibe combination therapy was non-inferior to high-intensity statin monotherapy for the 3-year composite outcomes with a higher proportion of patients with LDL cholesterol concentrations of less than 70 mg/dL and lower intolerance-related drug discontinuation or dose reduction.\n\n\nFUNDING\nHanmi Pharmaceutical.", "year": 2022, "publicationDate": "2022-07-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 212, "referenceCount": 27, "influentialCitationCount": 11, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S0140673622009163?via%3Dihub", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "144042779", "name": "Byeong‐Keuk Kim"}, {"authorId": "2435959518", "name": "S. Hong"}, {"authorId": "2109263202", "name": "Yong-Joon Lee"}, {"authorId": "2267276711", "name": "S. Hong"}, {"authorId": "4907958", "name": "K. Yun"}, {"authorId": "36931272", "name": "B. Hong"}, {"authorId": "50234027", "name": "J. Heo"}, {"authorId": "4625168", "name": "S. Rha"}, {"authorId": "72760478", "name": "Yun‐Hyeong Cho"}, {"authorId": "2108154798", "name": "Seung-Jun Lee"}, {"authorId": "46374746", "name": "C. Ahn"}, {"authorId": "22567359", "name": "Jung‐Sun Kim"}, {"authorId": "143766477", "name": "Y. Ko"}, {"authorId": "50614686", "name": "D. Choi"}, {"authorId": "66587645", "name": "Y. Jang"}, {"authorId": "1723368", "name": "M. Hong"}], "url": "https://www.semanticscholar.org/paper/ba7b42aab245ba583e1a7be6d401ff07dde9061f", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "1d2d2d346b517da0d74d538bfcc04be839af40db", "title": "Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study.", "abstract": "BACKGROUND\nThere is a paucity of data on the prevalence of risk factors and their associations with incident cardiovascular disease in women compared with men, especially from low-income and middle-income countries.\n\n\nMETHODS\nIn the Prospective Urban Rural Epidemiological (PURE) study, we enrolled participants from the general population from 21 high-income, middle-income, and low-income countries and followed them up for approximately 10 years. We recorded information on participants' metabolic, behavioural, and psychosocial risk factors. For this analysis, we included participants aged 35-70 years at baseline without a history of cardiovascular disease, with at least one follow-up visit. The primary outcome was a composite of major cardiovascular events (cardiovascular disease deaths, myocardial infarction, stroke, and heart failure). We report the prevalence of each risk factor in women and men, their hazard ratios (HRs), and population-attributable fractions (PAFs) associated with major cardiovascular disease. The PURE study is registered with ClinicalTrials.gov, NCT03225586.\n\n\nFINDINGS\nIn this analysis, we included 155 724 participants enrolled and followed-up between Jan 5, 2005, and Sept 13, 2021, (90 934 [58·4%] women and 64 790 [41·6%] men), with a median follow-up of 10·1 years (IQR 8·5-12·0). At study entry, the mean age of women was 49·8 years (SD 9·7) compared with 50·8 years (9·8) in men. As of data cutoff (Sept 13, 2021), 4280 major cardiovascular disease events had occurred in women (age-standardised incidence rate of 5·0 events [95% CI 4·9-5·2] per 1000 person-years) and 4911 in men (8·2 [8·0-8·4] per 1000 person-years). Compared with men, women presented with a more favourable cardiovascular risk profile, especially at younger ages. The HRs for metabolic risk factors were similar in women and men, except for non-HDL cholesterol, for which high non-HDL cholesterol was associated with an HR for major cardiovascular disease of 1·11 (95% CI 1·01-1·21) in women and 1·28 (1·19-1·39) in men, with a consistent pattern for higher risk among men than among women with other lipid markers. Symptoms of depression had a HR of 1·09 (0·98-1·21) in women and 1·42 (1·25-1·60) in men. By contrast, consumption of a diet with a PURE score of 4 or lower (score ranges from 0 to 8), was more strongly associated with major cardiovascular disease in women (1·17 [1·08-1·26]) than in men (1·07 [0·99-1·15]). The total PAFs associated with behavioural and psychosocial risk factors were greater in men (15·7%) than in women (8·4%) predominantly due to the larger contribution of smoking to PAFs in men (ie, 1·3% [95% CI 0·5-2·1] in women vs 10·7% [8·8-12·6] in men).\n\n\nINTERPRETATION\nLipid markers and depression are more strongly associated with the risk of cardiovascular disease in men than in women, whereas diet is more strongly associated with the risk of cardiovascular disease in women than in men. The similar associations of other risk factors with cardiovascular disease in women and men emphasise the importance of a similar strategy for the prevention of cardiovascular disease in men and women.\n\n\nFUNDING\nFunding sources are listed at the end of the Article.", "year": 2022, "publicationDate": "2022-09-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          811-821\n        ", "volume": "400 10355"}, "citationCount": 108, "referenceCount": 35, "influentialCitationCount": 7, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Psychology", "source": "s2-fos-model"}], "authors": [{"authorId": "1413719128", "name": "M. Walli-Attaei"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "13873313", "name": "Y. Breet"}, {"authorId": "152730155", "name": "S. Abdul-Razak"}, {"authorId": "2184321535", "name": "W. Sharief"}, {"authorId": "3658822", "name": "K. Alhabib"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "2068260581", "name": "R. Díaz"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "1830393563", "name": "B. Hu"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "40548968", "name": "R. Ismail"}, {"authorId": "4924433", "name": "R. Kelishadi"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "2114837813", "name": "X. Lang"}, {"authorId": "2118154469", "name": "Sidong Li"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "2075337902", "name": "V. Mohan"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "1411045076", "name": "Lia M. Palileo-Villanueva"}, {"authorId": "1404787589", "name": "K. Połtyn-Zaradna"}, {"authorId": "2184323182", "name": "R. SreelakshmiP"}, {"authorId": "1404791145", "name": "Lakshmi Pinnaka"}, {"authorId": "3831881", "name": "P. Serón"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "51110761", "name": "Sejil T Verghese"}, {"authorId": "145572557", "name": "A. Wielgosz"}, {"authorId": "3947311", "name": "K. Yeates"}, {"authorId": "47572577", "name": "R. Yusuf"}, {"authorId": "145276610", "name": "Sonia S Anand"}, {"authorId": "144636285", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/1d2d2d346b517da0d74d538bfcc04be839af40db", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "c69769936f4ea824980ca8d8dc7cd1e146d1ebeb", "title": "Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis.", "abstract": "BACKGROUND\nIn randomised controlled trials, fixed-dose combination treatments (or polypills) have been shown to reduce a composite of cardiovascular disease outcomes in primary prevention. However, whether or not aspirin should be included, effects on specific outcomes, and effects in key subgroups are unknown.\n\n\nMETHODS\nWe did an individual participant data meta-analysis of large randomised controlled trials (each with ≥1000 participants and ≥2 years of follow-up) of a fixed-dose combination treatment strategy versus control in a primary cardiovascular disease prevention population. We included trials that evaluated a fixed-dose combination strategy of at least two blood pressure lowering agents plus a statin (with or without aspirin), compared with a control strategy (either placebo or usual care). The primary outcome was time to first occurrence of a composite of cardiovascular death, myocardial infarction, stroke, or arterial revascularisation. Additional outcomes included individual cardiovascular outcomes and death from any cause. Outcomes were also evaluated in groups stratified by the inclusion of aspirin in the fixed-dose treatment strategy, and effect sizes were estimated in prespecified subgroups based on risk factors. Kaplan-Meier survival curves and Cox proportional hazard regression models were used to compare strategies.\n\n\nFINDINGS\nThree large randomised trials were included in the analysis (TIPS-3, HOPE-3, and PolyIran), with a total of 18 162 participants. Mean age was 63·0 years (SD 7·1), and 9038 (49·8%) participants were female. Estimated 10-year cardiovascular disease risk for the population was 17·7% (8·7). During a median follow-up of 5 years, the primary outcome occurred in 276 (3·0%) participants in the fixed-dose combination strategy group compared with 445 (4·9%) in the control group (hazard ratio 0·62, 95% CI 0·53-0·73, p<0·0001). Reductions were also observed for the separate components of the primary outcome: myocardial infarction (0·52, 0·38-0·70), revascularisation (0·54, 0·36-0·80), stroke (0·59, 0·45-0·78), and cardiovascular death (0·65, 0·52-0·81). Significant reductions in the primary outcome and its components were observed in the analyses of fixed-dose combination strategies with and without aspirin, with greater reductions for strategies including aspirin. Treatment effects were similar at different lipid and blood pressure levels, and in the presence or absence of diabetes, smoking, or obesity. Gastrointestinal bleeding was uncommon but slightly more frequent in the fixed-dose combination strategy with aspirin group versus control (19 [0·4%] vs 11 [0·2%], p=0·15). The frequencies of haemorrhagic stroke (10 [0·2%] vs 15 [0·3%]), fatal bleeding (two [<0·1%] vs four [0·1%]), and peptic ulcer disease (32 [0·7%] vs 34 [0·8%]) were low and did not differ significantly between groups. Dizziness was more common with fixed-dose combination treatment (1060 [11·7%] vs 834 [9·2%], p<0·0001).\n\n\nINTERPRETATION\nFixed-dose combination treatment strategies substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularisation, and cardiovascular death in primary cardiovascular disease prevention. These benefits are consistent irrespective of cardiometabolic risk factors.\n\n\nFUNDING\nPopulation Health Research Institute.", "year": 2021, "publicationDate": "2021-08-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 103, "referenceCount": 29, "influentialCitationCount": 6, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145364229", "name": "P. Joseph"}, {"authorId": "5709125", "name": "G. Roshandel"}, {"authorId": "1937104", "name": "P. Gao"}, {"authorId": "50169177", "name": "P. Pais"}, {"authorId": "6798050", "name": "E. Lonn"}, {"authorId": "1950718", "name": "D. Xavier"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "145296845", "name": "Jun Zhu"}, {"authorId": "2109292071", "name": "Li-sheng Liu"}, {"authorId": "153654062", "name": "K. Sliwa"}, {"authorId": "3544074", "name": "H. Gamra"}, {"authorId": "2926304", "name": "S. Bangdiwala"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "2113925707", "name": "A. Dans"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "145574924", "name": "D. Prabhakaran"}, {"authorId": "145023778", "name": "J. Castellano"}, {"authorId": "2106839338", "name": "Valentín Fuster"}, {"authorId": "145188451", "name": "A. Rodgers"}, {"authorId": "4772883", "name": "Mark D. Huffman"}, {"authorId": "144948213", "name": "J. Bosch"}, {"authorId": "4317457", "name": "G. Dagenais"}, {"authorId": "143980596", "name": "R. Malekzadeh"}, {"authorId": "144636283", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/c69769936f4ea824980ca8d8dc7cd1e146d1ebeb", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "12dec7e371a65ba330d4f7ded1891835399d5a0b", "title": "Modifiable risk factors, cardiovascular disease and mortality in 155,722 individuals from 21 high-, middle-, and low-income countries", "abstract": "Background: Global estimates of the impact of common modifiable risk factors on cardiovascular disease (CVD) and mortality are largely based on data from separate studies, using different methodologies. The Prospective Urban Rural Epidemiology (PURE) study overcomes these limitations by using similar methodology to prospectively evaluate the impact of modifiable risk factors on CVD and mortality across 21 countries (spanning five continents) at different economic levels. Methods: In a multi-national, prospective cohort study, we examined associations for 14 potentially modifiable risk factors with mortality and major CVD in 155,722 community-dwelling participants (ages 35–70 years at enrollment) from 21 high-, middle-, or low-income countries (HIC, MIC or LIC) followed for a median of 9·5 years. We describe the prevalence, hazard ratios, and population attributable fractions (PAFs) for CVD and mortality associated with a cluster of behavioural factors (i.e. tobacco, alcohol, diet, physical activity and sodium intake), metabolic factors (i.e. lipids, blood pressure, diabetes, obesity), socioeconomic and psychosocial factors (i.e. education, symptoms of depression), strength, household (solid fuel for cooking) and ambient PM 2·5 air pollution. Findings: Mean age of the population was 50·2 years of age, 58·3% were female, 52·6% were from urban areas, 11·1% from HIC, 65·9% from MIC, and 23·0% from LIC. Over 70% of CVD cases and deaths in the overall cohort were attributed to modifiable risk factors. Metabolic factors were the predominant risk factors for CVD (41·2% of the PAF), with hypertension being the largest (22·3% of the PAF). As a cluster, behavioural risk factors contributed most to deaths (26·3% of the PAF), although the single largest risk factor was a low education level (12.5% of the PAF). Ambient air pollution was associated with 13·9% of the PAF for CVD (although different statistical methods were used for this analysis). In MIC and LIC, the importance of household air pollution, poor diet, low education, and low grip strength were larger compared with HIC. Interpretation: The majority of CVD cases and deaths can be attributed to a small number of common, modifiable risk factors. While some factors have extensive global impacts (e.g. hypertension, education), others (e.g. household air pollution, poor diet) vary by a country’s economic level. Health policies should focus on risk factors that have the greatest effects on averting CVD and death globally, with additional emphasis on risk factors of greatest importance in specific groups of countries.", "year": 2019, "publicationDate": "2019-09-03", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "795 - 808", "volume": "395"}, "citationCount": 1330, "referenceCount": 23, "influentialCitationCount": 27, "isOpenAccess": true, "openAccessPdfUrl": "https://www.ncbi.nlm.nih.gov/pmc/articles/8006904", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "144636283", "name": "S. Yusuf"}, {"authorId": "145364229", "name": "P. Joseph"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "40146339", "name": "S. Islam"}, {"authorId": "5852860", "name": "A. Mente"}, {"authorId": "49012027", "name": "P. Hystad"}, {"authorId": "144460179", "name": "M. Brauer"}, {"authorId": "4693150", "name": "V. Kutty"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "145572557", "name": "A. Wielgosz"}, {"authorId": "3658822", "name": "K. Alhabib"}, {"authorId": "2113925707", "name": "A. Dans"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "144226747", "name": "F. Lanas"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "7002694", "name": "Iolanthé Marike Kruger"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "1977461", "name": "K. Yusoff"}, {"authorId": "9000040", "name": "P. Mony"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "3947311", "name": "K. Yeates"}, {"authorId": "4924433", "name": "R. Kelishadi"}, {"authorId": "37021165", "name": "A. Yusufali"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "48901309", "name": "O. Rahman"}, {"authorId": "6547067", "name": "K. Zatońska"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "2113553874", "name": "Li Wei"}, {"authorId": "2053703770", "name": "Hu Bo"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "49650926", "name": "Manmeet Kaur"}, {"authorId": "2075337902", "name": "V. Mohan"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "2591944", "name": "K. Teo"}, {"authorId": "5744161", "name": "D. Leong"}, {"authorId": "145482133", "name": "M. O’Donnell"}, {"authorId": "144228140", "name": "M. Mckee"}, {"authorId": "4317457", "name": "G. Dagenais"}], "url": "https://www.semanticscholar.org/paper/12dec7e371a65ba330d4f7ded1891835399d5a0b", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "fc76a1ebd7756baa3db7e8bdd66b2327326f543b", "title": "Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.", "abstract": null, "year": 2016, "publicationDate": "2016-03-05", "publicationTypes": ["Review", "MetaAnalysis", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          957-967\n        ", "volume": "387 10022"}, "citationCount": 3007, "referenceCount": 72, "influentialCitationCount": 99, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2401110477", "name": "Dena Ettehad"}, {"authorId": "3594074", "name": "C. Emdin"}, {"authorId": "2260580857", "name": "Amit Kiran"}, {"authorId": "145694558", "name": "S. Anderson"}, {"authorId": "5443154", "name": "T. Callender"}, {"authorId": "5029279", "name": "J. Emberson"}, {"authorId": "145973521", "name": "J. Chalmers"}, {"authorId": "145188451", "name": "A. Rodgers"}, {"authorId": "3296992", "name": "K. Rahimi"}], "url": "https://www.semanticscholar.org/paper/fc76a1ebd7756baa3db7e8bdd66b2327326f543b", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "1ad050e5fbdc47342207dbc05c215b9436dc8a86", "title": "Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis", "abstract": "Summary Background The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-pressure-lowering treatment on the risk of major cardiovascular events in groups of patients stratified by age and blood pressure at baseline. Methods We did a meta-analysis using individual participant-level data from randomised controlled trials of pharmacological blood-pressure-lowering versus placebo or other classes of blood-pressure-lowering medications, or between more versus less intensive treatment strategies, which had at least 1000 persons-years of follow-up in each treatment group. Participants with previous history of heart failure were excluded. Data were obtained from the Blood Pressure Lowering Treatment Triallists' Collaboration. We pooled the data and categorised participants into baseline age groups (<55 years, 55–64 years, 65–74 years, 75–84 years, and ≥85 years) and blood pressure categories (in 10 mm Hg increments from <120 mm Hg to ≥170 mm Hg systolic blood pressure and from <70 mm Hg to ≥110 mm Hg diastolic). We used a fixed effects one-stage approach and applied Cox proportional hazard models, stratified by trial, to analyse the data. The primary outcome was defined as either a composite of fatal or non-fatal stroke, fatal or non-fatal myocardial infarction or ischaemic heart disease, or heart failure causing death or requiring hospital admission. Findings We included data from 358 707 participants from 51 randomised clinical trials. The age of participants at randomisation ranged from 21 years to 105 years (median 65 years [IQR 59–75]), with 42 960 (12·0%) participants younger than 55 years, 128 437 (35·8%) aged 55–64 years, 128 506 (35·8%) 65–74 years, 54 016 (15·1%) 75–84 years, and 4788 (1·3%) 85 years and older. The hazard ratios for the risk of major cardiovascular events per 5 mm Hg reduction in systolic blood pressure for each age group were 0·82 (95% CI 0·76–0·88) in individuals younger than 55 years, 0·91 (0·88–0·95) in those aged 55–64 years, 0·91 (0·88–0·95) in those aged 65–74 years, 0·91 (0·87–0·96) in those aged 75–84 years, and 0·99 (0·87–1·12) in those aged 85 years and older (adjusted pinteraction=0·050). Similar patterns of proportional risk reductions were observed for a 3 mm Hg reduction in diastolic blood pressure. Absolute risk reductions for major cardiovascular events varied by age and were larger in older groups (adjusted pinteraction=0·024). We did not find evidence for any clinically meaningful heterogeneity of relative treatment effects across different baseline blood pressure categories in any age group. Interpretation Pharmacological blood pressure reduction is effective into old age, with no evidence that relative risk reductions for prevention of major cardiovascular events vary by systolic or diastolic blood pressure levels at randomisation, down to less than 120/70 mm Hg. Pharmacological blood pressure reduction should, therefore, be considered an important treatment option regardless of age, with the removal of age-related blood-pressure thresholds from international guidelines. Funding British Heart Foundation, National Institute of Health Research Oxford Biomedical Research Centre, Oxford Martin School.", "year": 2021, "publicationDate": "2021-08-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "1053 - 1064", "volume": "398"}, "citationCount": 192, "referenceCount": 47, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673621019218/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": null, "name": "Kazem Zeinab Milad Emma Dexter Malgorzata Jeannette Rich Rahimi Bidel Nazarzadeh Copland Canoy Wamil Majert"}, {"authorId": "3296992", "name": "K. Rahimi"}, {"authorId": "4703742", "name": "Z. Bidel"}, {"authorId": "2409853", "name": "M. Nazarzadeh"}, {"authorId": "48539179", "name": "E. Copland"}, {"authorId": "4547530", "name": "D. Canoy"}, {"authorId": "46546488", "name": "M. Wamil"}, {"authorId": "15788863", "name": "Jeannette Majert"}, {"authorId": "2095500530", "name": "Richard McManus"}, {"authorId": "2113859664", "name": "A. Adler"}, {"authorId": "34046547", "name": "L. Agodoa"}, {"authorId": "145486242", "name": "A. Algra"}, {"authorId": "39458739", "name": "F. Asselbergs"}, {"authorId": "4323309", "name": "N. Beckett"}, {"authorId": "113010352", "name": "E. Berge"}, {"authorId": "4474719", "name": "H. Black"}, {"authorId": "50276643", "name": "E. Boersma"}, {"authorId": "7889636", "name": "F. P. Brouwers"}, {"authorId": "153856948", "name": "MorrisJ. Brown"}, {"authorId": "4299204", "name": "J. Brugts"}, {"authorId": "143892455", "name": "C. Bulpitt"}, {"authorId": "81152256", "name": "R. Byington"}, {"authorId": "6455627", "name": "W. Cushman"}, {"authorId": "84278208", "name": "Jeffrey Cutler"}, {"authorId": "79582376", "name": "R. Devereaux"}, {"authorId": "2402475", "name": "J. Dwyer"}, {"authorId": "6925635", "name": "R. Estacio"}, {"authorId": "3856244", "name": "R. Fagard"}, {"authorId": "2111997798", "name": "K. Fox"}, {"authorId": "3289886", "name": "T. Fukui"}, {"authorId": "2110020123", "name": "Ajay K. Gupta"}, {"authorId": "2317710", "name": "R. Holman"}, {"authorId": "32633461", "name": "Y. Imai"}, {"authorId": "1845200", "name": "M. Ishii"}, {"authorId": "2052439112", "name": "S. Julius"}, {"authorId": "3493975", "name": "Y. Kanno"}, {"authorId": "6213357", "name": "S. Kjeldsen"}, {"authorId": "6020227", "name": "J. Kostis"}, {"authorId": "1700550", "name": "K. Kuramoto"}, {"authorId": "4348490", "name": "J. Lanke"}, {"authorId": "2068825188", "name": "E. Lewis"}, {"authorId": "2109189895", "name": "J. Lewis"}, {"authorId": "143884449", "name": "M. Lièvre"}, {"authorId": "5278153", "name": "L. Lindholm"}, {"authorId": "144784042", "name": "S. Lueders"}, {"authorId": "48040733", "name": "S. MacMahon"}, {"authorId": "6478764", "name": "G. Mancia"}, {"authorId": "32500162", "name": "M. Matsuzaki"}, {"authorId": "14559133", "name": "M. Mehlum"}, {"authorId": "3844310", "name": "S. Nissen"}, {"authorId": "48145507", "name": "H. Ogawa"}, {"authorId": "2504477", "name": "T. Ogihara"}, {"authorId": "145022633", "name": "T. Ohkubo"}, {"authorId": "143613706", "name": "C. Palmer"}, {"authorId": "4138511", "name": "Anushka Patel"}, {"authorId": "145436306", "name": "M. Pfeffer"}, {"authorId": "144526806", "name": "B. Pitt"}, {"authorId": "6786258", "name": "N. Poulter"}, {"authorId": "5030920", "name": "H. Rakugi"}, {"authorId": "3681615", "name": "G. Reboldi"}, {"authorId": "2052732422", "name": "C. Reid"}, {"authorId": "8390357", "name": "G. Remuzzi"}, {"authorId": "2867767", "name": "P. Ruggenenti"}, {"authorId": "4356295", "name": "T. Saruta"}, {"authorId": "2061479813", "name": "Joachim Schrader"}, {"authorId": "144560419", "name": "R. Schrier"}, {"authorId": "2099887194", "name": "P. Sever"}, {"authorId": "4797329", "name": "P. Sleight"}, {"authorId": "47149250", "name": "J. Staessen"}, {"authorId": "2111603801", "name": "Hiromichi Suzuki"}, {"authorId": "5265019", "name": "L. Thijs"}, {"authorId": "6916138", "name": "K. Ueshima"}, {"authorId": "5510813", "name": "S. Umemoto"}, {"authorId": "5896382", "name": "W. V. van Gilst"}, {"authorId": "4463638", "name": "P. Verdecchia"}, {"authorId": "3737835", "name": "K. Wachtell"}, {"authorId": "6352525", "name": "P. Whelton"}, {"authorId": "2268042", "name": "L. Wing"}, {"authorId": "145037492", "name": "M. Woodward"}, {"authorId": "2109254", "name": "Y. Yui"}, {"authorId": "144636283", "name": "S. Yusuf"}, {"authorId": "3559625", "name": "A. Zanchetti"}, {"authorId": "50316136", "name": "Zhenyu Zhang"}, {"authorId": "2116941132", "name": "C. Anderson"}, {"authorId": "5278382", "name": "C. Baigent"}, {"authorId": "4001102", "name": "B. Brenner"}, {"authorId": "2412365719", "name": "R. Collins"}, {"authorId": "80518345", "name": "D. de Zeeuw"}, {"authorId": "6644958", "name": "J. Lubsen"}, {"authorId": "7349028", "name": "E. Malacco"}, {"authorId": "145259700", "name": "B. Neal"}, {"authorId": "4409983", "name": "V. Perkovic"}, {"authorId": "145188451", "name": "A. Rodgers"}, {"authorId": "152722719", "name": "P. Rothwell"}, {"authorId": "1402005227", "name": "G. Salimi-Khorshidi"}, {"authorId": "144023638", "name": "J. Sundström"}, {"authorId": "3659160", "name": "F. Turnbull"}, {"authorId": "32127108", "name": "G. Viberti"}, {"authorId": "2110139568", "name": "Jiguang Wang"}, {"authorId": "2054101022", "name": "J. Chalmers"}, {"authorId": "39757654", "name": "B. Davis"}, {"authorId": "5479974", "name": "C. Pepine"}, {"authorId": "2591944", "name": "K. Teo"}], "url": "https://www.semanticscholar.org/paper/1ad050e5fbdc47342207dbc05c215b9436dc8a86", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "95617ae716e49f4465e6cf72c984001a064e14f5", "title": "Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.", "abstract": null, "year": 2018, "publicationDate": null, "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1519-1529\n        ", "volume": "392 10157"}, "citationCount": 1447, "referenceCount": 23, "influentialCitationCount": 55, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S014067361832261X/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145577288", "name": "Adrian F. Hernandez"}, {"authorId": "2113479965", "name": "Jennifer B. Green"}, {"authorId": "39769879", "name": "Salim Janmohamed"}, {"authorId": "80899776", "name": "R. D'Agostino"}, {"authorId": "3022170", "name": "C. Granger"}, {"authorId": "5653939", "name": "N. Jones"}, {"authorId": "4438784", "name": "Lawrence A Leiter"}, {"authorId": "2109960419", "name": "A. Rosenberg"}, {"authorId": "10153830", "name": "K. Sigmon"}, {"authorId": "6501388", "name": "M. Somerville"}, {"authorId": "51115712", "name": "Karl M Thorpe"}, {"authorId": "2086700759", "name": "J. McMurray"}, {"authorId": "2224131", "name": "S. Prato"}, {"authorId": "2086700759", "name": "J. McMurray"}, {"authorId": "80899776", "name": "R. D'Agostino"}, {"authorId": "3022170", "name": "C. Granger"}, {"authorId": "145577288", "name": "Adrian F. Hernandez"}, {"authorId": "4438784", "name": "Lawrence A Leiter"}, {"authorId": "2052004", "name": "R. Califf"}, {"authorId": "2317710", "name": "R. Holman"}, {"authorId": "2130281", "name": "D. DeMets"}, {"authorId": "34597626", "name": "M. Riddle"}, {"authorId": "6253036", "name": "S. Goodman"}, {"authorId": "6611621", "name": "D. McGuire"}, {"authorId": "2072267517", "name": "K. Alexander"}, {"authorId": "3872081", "name": "A. DeVore"}, {"authorId": "50476630", "name": "C. Melloni"}, {"authorId": "2057928955", "name": "Chetan R. Patel"}, {"authorId": "152587368", "name": "D. Kong"}, {"authorId": "6385246", "name": "Gerald S Bloomfield"}, {"authorId": "9750027", "name": "M. Roe"}, {"authorId": "6099057", "name": "P. Tricoci"}, {"authorId": "49599209", "name": "R. Harrison"}, {"authorId": "143686509", "name": "R. Lopes"}, {"authorId": "5969664", "name": "R. Mathews"}, {"authorId": "144151551", "name": "R. Mehta"}, {"authorId": "49148806", "name": "W. Jones"}, {"authorId": "2294489", "name": "S. Vemulapalli"}, {"authorId": "5794146", "name": "T. Povsic"}, {"authorId": "5821437", "name": "Zubin J. Eapen"}, {"authorId": "47965755", "name": "K. Dombrowski"}, {"authorId": "4838760", "name": "B. Kolls"}, {"authorId": "1409627275", "name": "Dedrick Jordan"}, {"authorId": "2862983", "name": "A. Ambrosy"}, {"authorId": "2007628", "name": "S. Greene"}, {"authorId": "2390835364", "name": "Aditya Mandawat"}, {"authorId": "49087602", "name": "J. Shavadia"}, {"authorId": "2305629", "name": "L. Cooper"}, {"authorId": "2109325370", "name": "Abhinav Sharma"}, {"authorId": "48737726", "name": "P. Guimarães"}, {"authorId": "145886759", "name": "D. Friedman"}, {"authorId": "152827143", "name": "Matt Wilson"}, {"authorId": "117810419", "name": "P. Endsley"}, {"authorId": "117593296", "name": "T. Gentry"}, {"authorId": "2070317754", "name": "J. Collier"}, {"authorId": "83820236", "name": "K. Perez"}, {"authorId": "2069469329", "name": "K. James"}, {"authorId": "66480403", "name": "Jennifer E. Roush"}, {"authorId": "2068649614", "name": "C. Pope"}, {"authorId": "87729975", "name": "Christina Howell"}, {"authorId": "2109675991", "name": "Megan Johnson"}, {"authorId": "144316432", "name": "M. Bailey"}, {"authorId": "2069465129", "name": "Joanna Cole"}, {"authorId": "2241465543", "name": "T. Akers"}, {"authorId": "116120923", "name": "B. Vandyne"}, {"authorId": "48304418", "name": "Betsy Thomas"}, {"authorId": "122227899", "name": "J. Rich"}, {"authorId": "2111567259", "name": "Susan Bartone"}, {"authorId": "2084019528", "name": "G. Beaulieu"}, {"authorId": "2109645469", "name": "Kim Brown"}, {"authorId": "89227157", "name": "T. Chau"}, {"authorId": "2111561926", "name": "Tamra Christian"}, {"authorId": "46974835", "name": "Rebecca Coker"}, {"authorId": "2059011037", "name": "Deborah Greene"}, {"authorId": "2111563189", "name": "Trevorlyn Haddock"}, {"authorId": "1463489050", "name": "Wendy M. Jenkins"}, {"authorId": "2084238818", "name": "Ghazala Haque"}, {"authorId": "11512514", "name": "M. Marquess"}, {"authorId": "2111567510", "name": "Jean Pesarchick"}, {"authorId": "2111569079", "name": "Renee Rethaford"}, {"authorId": "1620546470", "name": "Allegra Stone"}, {"authorId": "80518431", "name": "F. A. Kawas"}, {"authorId": "32769643", "name": "Michelle Anderson"}, {"authorId": "3888789", "name": "R. Enns"}, {"authorId": "5641915", "name": "I. Sinay"}, {"authorId": "145255822", "name": "C. Mathieu"}, {"authorId": "2335031712", "name": "V. Yordanov"}, {"authorId": "5325310", "name": "I. Hramiak"}, {"authorId": "2104671", "name": "M. Haluzík"}, {"authorId": "5763136", "name": "S. Galatius"}, {"authorId": "3751805", "name": "B. Guerci"}, {"authorId": "144120563", "name": "M. Nauck"}, {"authorId": "5567279", "name": "I. Migdalis"}, {"authorId": "2111728680", "name": "Choon Beng Kathryn Tan"}, {"authorId": "2084298671", "name": "G. Kocsis"}, {"authorId": "6693759", "name": "A. Giaccari"}, {"authorId": "7793548", "name": "Moon-Kyu Lee"}, {"authorId": "12898761", "name": "E. Muñoz"}, {"authorId": "33974612", "name": "J. Cornel"}, {"authorId": "2784964", "name": "K. Birkeland"}, {"authorId": "2435539445", "name": "M. Pinto"}, {"authorId": "1401208714", "name": "L. Tirador"}, {"authorId": "1435306978", "name": "M. Olesińska-Mader"}, {"authorId": "3598132", "name": "M. Shestakova"}, {"authorId": "6322704", "name": "L. Distiller"}, {"authorId": "1389542225", "name": "J. López-Sendón"}, {"authorId": "2505547", "name": "B. Eliasson"}, {"authorId": "145464264", "name": "C. Chiang"}, {"authorId": "8107915", "name": "S. Srimahachota"}, {"authorId": "2386070492", "name": "B. Mankovsky"}, {"authorId": "2111102", "name": "M. A. Bethel"}, {"authorId": "90906219", "name": "K. Dungan"}, {"authorId": "4027961", "name": "M. Kosiborod"}, {"authorId": "2111563135", "name": "A. Alvarisqueta"}, {"authorId": "2348811040", "name": "J. Baldovino"}, {"authorId": "2111487323", "name": "D. Besada"}, {"authorId": "2111568998", "name": "Pedro R F Calella"}, {"authorId": "123705980", "name": "M. C. Cantero"}, {"authorId": "1742425280", "name": "Patricia R. Castaño"}, {"authorId": "17025541", "name": "A. Chertkoff"}, {"authorId": "2059472292", "name": "J. Cuadrado"}, {"authorId": "2094911447", "name": "L. D. Loredo"}, {"authorId": "2054606347", "name": "A. Domínguez"}, {"authorId": "2111567224", "name": "Maria Vanesa Español"}, {"authorId": "2111569131", "name": "H. Finkelstein"}, {"authorId": "6712476", "name": "G. Frechtel"}, {"authorId": "134160825", "name": "José Fretes"}, {"authorId": "2111441896", "name": "Natalia Garrido Santos"}, {"authorId": "2119114853", "name": "Joaquin Gonzalez"}, {"authorId": "2065680341", "name": "M. Litvak"}, {"authorId": "84639066", "name": "Juan Loureyro"}, {"authorId": "50497114", "name": "L. Maffei"}, {"authorId": "152934731", "name": "N. Maldonado"}, {"authorId": "2111561121", "name": "D. Gasparini"}, {"authorId": "2037018887", "name": "Silvia Orio"}, {"authorId": "49488887", "name": "F. P. Manghi"}, {"authorId": "2111567114", "name": "Nelson Rodriguez Papini"}, {"authorId": "2111464952", "name": "Jorgelina Sala"}, {"authorId": "1621187416", "name": "P. Schygiel"}, {"authorId": "7623897", "name": "G. Sposetti"}, {"authorId": "145149517", "name": "M. Ulla"}, {"authorId": "2083934915", "name": "Fernando Verra"}, {"authorId": "2111567465", "name": "Silvina Zabalua"}, {"authorId": "2111469826", "name": "C. Zaidman"}, {"authorId": "8449330", "name": "L. Crenier"}, {"authorId": "35526356", "name": "Corinne Debroye"}, {"authorId": "2111566524", "name": "Francis Duyck"}, {"authorId": "2059044173", "name": "A. Scheen"}, {"authorId": "8310222", "name": "L. Gaal"}, {"authorId": "40187440", "name": "C. Vercammen"}, {"authorId": "2111569812", "name": "V. Damyanova"}, {"authorId": "2066283740", "name": "S. Dimitrov"}, {"authorId": "2111562732", "name": "Snezhina Kovacheva"}, {"authorId": "14120075", "name": "L. Lozanov"}, {"authorId": "93129481", "name": "V. Margaritov"}, {"authorId": "2111563266", "name": "Rositsa Mihaylova-Shumkova"}, {"authorId": "145715112", "name": "A. Nikolaeva"}, {"authorId": "2111560818", "name": "Zhasmina Stoyanova"}, {"authorId": "1420976481", "name": "R. Akhras"}, {"authorId": "7261770", "name": "Y. Beaudry"}, {"authorId": "48000070", "name": "J. Bédard"}, {"authorId": "4334386", "name": "J. Berlingieri"}, {"authorId": "2111565069", "name": "Raja Chehayeb"}, {"authorId": "39526216", "name": "S. Cheung"}, {"authorId": "2052447723", "name": "James Conway"}, {"authorId": "5067186", "name": "J. Cusson"}, {"authorId": "40622041", "name": "A. D. Siega"}, {"authorId": "48501925", "name": "R. Dumas"}, {"authorId": "12527530", "name": "P. Dzongowski"}, {"authorId": "33750531", "name": "Murdo Ferguson"}, {"authorId": "144492311", "name": "D. Gaudet"}, {"authorId": "2386483", "name": "François R. Grondin"}, {"authorId": "2110759859", "name": "Anil Gupta"}, {"authorId": "89430734", "name": "M. Gupta"}, {"authorId": "49729451", "name": "F. Halperin"}, {"authorId": "144353186", "name": "P. Houle"}, {"authorId": "2111329266", "name": "Michael Jones"}, {"authorId": "4856952", "name": "S. Kouz"}, {"authorId": "2074972845", "name": "Christopher Kovacs"}, {"authorId": "31197168", "name": "D. Landry"}, {"authorId": "6798050", "name": "E. Lonn"}, {"authorId": "1404736410", "name": "W. O’Mahony"}, {"authorId": "2112082360", "name": "Sean D. Peterson"}, {"authorId": "37067571", "name": "D. Reich"}, {"authorId": "1486210006", "name": "Allan M. Rosenbloom"}, {"authorId": "1422057175", "name": "F. St-Maurice"}, {"authorId": "11522055", "name": "B. Tugwell"}, {"authorId": "1398331038", "name": "S. Vizel"}, {"authorId": "3038693", "name": "V. Woo"}, {"authorId": "3625894", "name": "T. Brychta"}, {"authorId": "2681216", "name": "V. Čech"}, {"authorId": "5072867", "name": "E. Dvořáková"}, {"authorId": "12404880", "name": "T. Edelsberger"}, {"authorId": "90020613", "name": "Katarína Halčiaková"}, {"authorId": "5608272", "name": "J. Křížová"}, {"authorId": "15324955", "name": "J. Laštůvka"}, {"authorId": "2111567292", "name": "Martin Piperek"}, {"authorId": "87405161", "name": "Vera Prymkova"}, {"authorId": "14729680", "name": "L. Raclavska"}, {"authorId": "1405442191", "name": "Elena Šilhová"}, {"authorId": "46402877", "name": "R. Urbánek"}, {"authorId": "15349261", "name": "J. Vrkoč"}, {"authorId": "40522993", "name": "U. Andersen"}, {"authorId": "1431038513", "name": "J. Brønnum-Schou"}, {"authorId": "69841124", "name": "J. Hove"}, {"authorId": "81269008", "name": "J. Jensen"}, {"authorId": "152159105", "name": "L. Køber"}, {"authorId": "5350579", "name": "O. Kristiansen"}, {"authorId": "123720863", "name": "Per Lund"}, {"authorId": "5730334", "name": "T. Melchior"}, {"authorId": "8476251", "name": "O. Nyvad"}, {"authorId": "35806275", "name": "M. Schou"}, {"authorId": "51125123", "name": "Alain Boye"}, {"authorId": "116920082", "name": "Didier Cadinot"}, {"authorId": "6901039", "name": "D. Gouet"}, {"authorId": "2059975912", "name": "P. Henry"}, {"authorId": "144950678", "name": "L. Kessler"}, {"authorId": "3526114", "name": "J. Lalau"}, {"authorId": "48821113", "name": "C. Petit"}, {"authorId": "144031823", "name": "J. Thuan"}, {"authorId": "31571970", "name": "C. Voinot"}, {"authorId": "7311285", "name": "J. Vouillarmet"}, {"authorId": "3865728", "name": "C. Axthelm"}, {"authorId": "2053459909", "name": "Dirk Berger"}, {"authorId": "2111479993", "name": "T. Bieler"}, {"authorId": "2375114382", "name": "A. Birkenfeld"}, {"authorId": "2111569071", "name": "Jochen Bott"}, {"authorId": "2062053247", "name": "K. Busch"}, {"authorId": "4535114", "name": "K. Caca"}, {"authorId": "15954746", "name": "Julia Chevts"}, {"authorId": "2111564780", "name": "Torsten Donaubauer"}, {"authorId": "2111562838", "name": "Rudolf Erlinger"}, {"authorId": "46775724", "name": "K. Funke"}, {"authorId": "47946010", "name": "J. Grosskopf"}, {"authorId": "4747183", "name": "A. Hagenow"}, {"authorId": "2057271516", "name": "Monika Hamann"}, {"authorId": "48531080", "name": "M. Hartard"}, {"authorId": "11362805", "name": "Peter Heymer"}, {"authorId": "2111569083", "name": "Wolfgang Huppertz"}, {"authorId": "2111560742", "name": "Gabriele Illies"}, {"authorId": "1775598", "name": "S. Jacob"}, {"authorId": "2055669021", "name": "T. Jung"}, {"authorId": "2316662599", "name": "G. Kahrmann"}, {"authorId": "39660823", "name": "P. Kast"}, {"authorId": "114862046", "name": "M. Kellerer"}, {"authorId": "121841081", "name": "H. Kempe"}, {"authorId": "12538114", "name": "A. Khariouzov"}, {"authorId": "12752321", "name": "G. Klausmann"}, {"authorId": "2060237284", "name": "C. Klein"}, {"authorId": "2111562831", "name": "Uwe Kleinecke-Pohl"}, {"authorId": "5211650", "name": "Klaus Kleinertz"}, {"authorId": "2054952460", "name": "Thorsten Koch"}, {"authorId": "2111479978", "name": "C. Kosch"}, {"authorId": "16317497", "name": "B. Lorra"}, {"authorId": "2076752562", "name": "J. Luedemann"}, {"authorId": "2273751922", "name": "M. Luttermann"}, {"authorId": "48486522", "name": "S. Maxeiner"}, {"authorId": "2075838685", "name": "K. Milek"}, {"authorId": "1738615806", "name": "Andre Moelle"}, {"authorId": "2055898846", "name": "G. Neumann"}, {"authorId": "1394631448", "name": "Ruth Nischik"}, {"authorId": "2111563952", "name": "Edith Oehrig-Pohl"}, {"authorId": "1887896", "name": "Georg Plassmann"}, {"authorId": "2111232447", "name": "Lars Pohlmeier"}, {"authorId": "2111562825", "name": "Felix Proepper"}, {"authorId": "11919045", "name": "Stefan Regner"}, {"authorId": "13751275", "name": "Werner Rieker"}, {"authorId": "47326234", "name": "L. Rose"}, {"authorId": "2085359760", "name": "Holger Samer"}, {"authorId": "69046368", "name": "J. Sauter"}, {"authorId": "3233697", "name": "F. Schaper"}, {"authorId": "2091083547", "name": "Clemens Schiffer"}, {"authorId": "2149399868", "name": "Juergen Schmidt"}, {"authorId": "117667839", "name": "B. Scholz"}, {"authorId": "2052778387", "name": "J. Schulze"}, {"authorId": "46470176", "name": "A. Segner"}, {"authorId": "145948837", "name": "J. Seufert"}, {"authorId": "2111562800", "name": "Helena Sigal"}, {"authorId": "2111564688", "name": "Joerg Steindorf"}, {"authorId": "2111562854", "name": "Juergen Stockhausen"}, {"authorId": "2111436015", "name": "Petra Stuebler"}, {"authorId": "2111567183", "name": "Heidrun Taeschner"}, {"authorId": "2111567209", "name": "D. Tews"}, {"authorId": "118320199", "name": "D. Tschoepe"}, {"authorId": "153610481", "name": "Karl Wilhelm"}, {"authorId": "2003034358", "name": "H. Zeller-Stefan"}, {"authorId": "6984744", "name": "Iakovos Avramidis"}, {"authorId": "5755197", "name": "S. Bousboulas"}, {"authorId": "5973346", "name": "M. Bristianou"}, {"authorId": "47121507", "name": "G. Dimitriadis"}, {"authorId": "2056074928", "name": "M. Elisaf"}, {"authorId": "5000340", "name": "K. Kotsa"}, {"authorId": "47490415", "name": "A. Melidonis"}, {"authorId": "4524232", "name": "A. Mitrakou"}, {"authorId": "7527447", "name": "E. Pagkalos"}, {"authorId": "6713106", "name": "N. Papanas"}, {"authorId": "1982370059", "name": "A. Pappas"}, {"authorId": "9965589", "name": "C. Sampanis"}, {"authorId": "66816373", "name": "N. Tentolouris"}, {"authorId": "5229596", "name": "A. Tsapas"}, {"authorId": "35454315", "name": "G. Tzatzagou"}, {"authorId": "2850372", "name": "R. Ozaki"}, {"authorId": "2405142589", "name": "C. Hajdu"}, {"authorId": "11645859", "name": "E. Harcsa"}, {"authorId": "1403400388", "name": "László Konyves"}, {"authorId": "1413218452", "name": "J. Mucsi"}, {"authorId": "12569252", "name": "Z. Pauker"}, {"authorId": "2075269119", "name": "G. Petró"}, {"authorId": "2111567162", "name": "Zsolt Plés"}, {"authorId": "49401529", "name": "K. Révész"}, {"authorId": "2258888617", "name": "V. Sándor"}, {"authorId": "122077967", "name": "Viktor Vass"}, {"authorId": "5079720", "name": "A. Avogaro"}, {"authorId": "2329496", "name": "M. Boemi"}, {"authorId": "6505634", "name": "R. Bonadonna"}, {"authorId": "3352350", "name": "A. Consoli"}, {"authorId": "14743828", "name": "S. Cosmo"}, {"authorId": "6739962", "name": "P. Bartolo"}, {"authorId": "5677483", "name": "F. Dotta"}, {"authorId": "6653320", "name": "S. Frontoni"}, {"authorId": "31585936", "name": "M. Galetta"}, {"authorId": "5485429", "name": "A. Gambineri"}, {"authorId": "3199677", "name": "C. Gazzaruso"}, {"authorId": "4238545", "name": "F. Giorgino"}, {"authorId": "4241177", "name": "D. Lauro"}, {"authorId": "34437707", "name": "E. Orsi"}, {"authorId": "4434602", "name": "G. Paolisso"}, {"authorId": "6386531", "name": "G. Perriello"}, {"authorId": "3777906", "name": "P. Piatti"}, {"authorId": "4922940", "name": "A. Pontiroli"}, {"authorId": "10090243", "name": "P. Ponzani"}, {"authorId": "4772555", "name": "A. Rivellese"}, {"authorId": "3585527", "name": "G. Sesti"}, {"authorId": "6866856", "name": "G. Tonolo"}, {"authorId": "145333192", "name": "R. Trevisan"}, {"authorId": "23640534", "name": "C. Ahn"}, {"authorId": "4705516", "name": "S. Baik"}, {"authorId": "66275028", "name": "B. Cha"}, {"authorId": "6613401", "name": "C. Chung"}, {"authorId": "1948156", "name": "H. Jang"}, {"authorId": "3547683", "name": "C. Kim"}, {"authorId": "2305110019", "name": "Hye Soon Kim"}, {"authorId": "35869932", "name": "I. Kim"}, {"authorId": "2115243635", "name": "Eun Young Lee"}, {"authorId": "3606240", "name": "H. Lee"}, {"authorId": "2145232493", "name": "K. Lee"}, {"authorId": "34501381", "name": "Keon-Woong Moon"}, {"authorId": "6143465", "name": "J. Namgung"}, {"authorId": "34520793", "name": "K. Park"}, {"authorId": "48803257", "name": "S. Yoo"}, {"authorId": "153174689", "name": "J. Yu"}, {"authorId": "1401898240", "name": "Edmundo Alfredo Bayram Llamas"}, {"authorId": "2111560752", "name": "Jose-Luis Cervantes-Escárcega"}, {"authorId": "2111566980", "name": "Luis Fernando Flota-Cervera"}, {"authorId": "1394346018", "name": "J. González‐González"}, {"authorId": "1413301883", "name": "S. Pascoe-González"}, {"authorId": "2111567340", "name": "Emilia Susana Pelayo-Orozco"}, {"authorId": "2111569101", "name": "Santiago-Paulino Ramirez-Diaz"}, {"authorId": "1422599726", "name": "A. Saldaña-Mendoza"}, {"authorId": "2111564600", "name": "Carlos Sánchez Jerjes-Díaz"}, {"authorId": "2111569094", "name": "Jose Juan Torres-Colores"}, {"authorId": "1421597586", "name": "Maricela Vidrio-Velázquez"}, {"authorId": "1429576533", "name": "Juan Villagordoa-Mesa"}, {"authorId": "2111560549", "name": "Hugo Peter Beijerbacht"}, {"authorId": "5835238", "name": "R. Groutars"}, {"authorId": "2111561152", "name": "Boudewijn A Hoek"}, {"authorId": "1398332285", "name": "P. Hoogslag"}, {"authorId": "144125127", "name": "A. Kooy"}, {"authorId": "6675404", "name": "J. Kragten"}, {"authorId": "5358556", "name": "A. Lieverse"}, {"authorId": "7299123", "name": "H. Swart"}, {"authorId": "5543096", "name": "E. Viergever"}, {"authorId": "2111393861", "name": "Jørn Ahlqvist"}, {"authorId": "28968661", "name": "J. Cooper"}, {"authorId": "4764670", "name": "H. Gulseth"}, {"authorId": "2111563869", "name": "Gaute Guttormsen"}, {"authorId": "40098927", "name": "Cecilie Wium"}, {"authorId": "15678694", "name": "H. Arbañil"}, {"authorId": "2068517895", "name": "Jorge Calderon"}, {"authorId": "2111568426", "name": "Luis Camacho"}, {"authorId": "2109949314", "name": "Augusto Dextre Espinoza"}, {"authorId": "2054289779", "name": "E. Garrido"}, {"authorId": "2064251912", "name": "A. Luna"}, {"authorId": "83532516", "name": "Helard Manrique"}, {"authorId": "2090042931", "name": "Frederick Massucco Revoredo"}, {"authorId": "2111567800", "name": "Rolando Gonzales"}, {"authorId": "2111563562", "name": "Luis Zapata Rincon"}, {"authorId": "1404967144", "name": "Carlos Zubiate"}, {"authorId": "2111548129", "name": "G. Ebo"}, {"authorId": "2111567288", "name": "Ellen Morales-Palomares"}, {"authorId": "49942280", "name": "M. Arciszewska"}, {"authorId": "2055542969", "name": "M. Banach"}, {"authorId": "1423235733", "name": "R. Bijata-Bronisz"}, {"authorId": "5671884", "name": "T. Dereziński"}, {"authorId": "1737254339", "name": "W. Gadzinski"}, {"authorId": "6717058", "name": "J. Gajek"}, {"authorId": "2111570449", "name": "Katarzyna Klodawska"}, {"authorId": "6110704", "name": "E. Krzyżagórska"}, {"authorId": "48989263", "name": "A. Madej"}, {"authorId": "4234275", "name": "P. Miękus"}, {"authorId": "2111567154", "name": "Jaroslaw Opiela"}, {"authorId": "2397404668", "name": "Piotr Romańczuk"}, {"authorId": "2053233927", "name": "Anna Siegel"}, {"authorId": "2111563196", "name": "Ewa Skokowska"}, {"authorId": "46632936", "name": "A. Stankiewicz"}, {"authorId": "14842881", "name": "Teresa Stasińska"}, {"authorId": "1432289431", "name": "Iwona Trznadel-Morawska"}, {"authorId": "134687689", "name": "Robert Witek"}, {"authorId": "66921838", "name": "S. Aksentyev"}, {"authorId": "2056035845", "name": "I. Bondar"}, {"authorId": "2076285364", "name": "I. Demidova"}, {"authorId": "145574770", "name": "A. Dreval"}, {"authorId": "2060403618", "name": "O. Ershova"}, {"authorId": "12634645", "name": "G. Galstyan"}, {"authorId": "2123817770", "name": "A. Garganeeva"}, {"authorId": "6452734", "name": "N. Izmozherova"}, {"authorId": "5914386", "name": "V. Karetnikova"}, {"authorId": "2316659207", "name": "Marina Kharakhulakh"}, {"authorId": "2080122389", "name": "A. Khokhlov"}, {"authorId": "47406936", "name": "Z. Kobalava"}, {"authorId": "50596224", "name": "O. Koshelskaya"}, {"authorId": "12723429", "name": "E. Kosmacheva"}, {"authorId": "91712367", "name": "V. Kostin"}, {"authorId": "152569641", "name": "N. Koziolova"}, {"authorId": "39120668", "name": "A. Kuzin"}, {"authorId": "2111567524", "name": "Victor Lesnov"}, {"authorId": "2134689251", "name": "T. Lysenko"}, {"authorId": "2074593880", "name": "Valentin Markov"}, {"authorId": "67100229", "name": "A. Mayorov"}, {"authorId": "2141129603", "name": "S. Moiseev"}, {"authorId": "52539430", "name": "S. Myasoedova"}, {"authorId": "47856791", "name": "N. Petunina"}, {"authorId": "52109917", "name": "A. Rebrov"}, {"authorId": "2111440937", "name": "L. Ruyatkina"}, {"authorId": "67176234", "name": "Julia Samoylova"}, {"authorId": "40609497", "name": "O. Sazonova"}, {"authorId": "150249399", "name": "Natalia E. Shilkina"}, {"authorId": "143938747", "name": "N. Sokolova"}, {"authorId": "81638816", "name": "O. Vasilevskaya"}, {"authorId": "51438848", "name": "N. Verbovaya"}, {"authorId": "2083297524", "name": "E. Vishneva"}, {"authorId": "9045911", "name": "S. Vorobyev"}, {"authorId": "2138298610", "name": "N. Vorokhobina"}, {"authorId": "12614887", "name": "O. Zanozina"}, {"authorId": "2083344318", "name": "E. Zhdanova"}, {"authorId": "6496447", "name": "T. Zykova"}, {"authorId": "32225333", "name": "L. Burgess"}, {"authorId": "151071668", "name": "K. Coetzee"}, {"authorId": "134707978", "name": "S. Dawood"}, {"authorId": "39857647", "name": "L. Lombard"}, {"authorId": "2111545800", "name": "Ellen Makotoko"}, {"authorId": "47143643", "name": "R. Moodley"}, {"authorId": "1404322044", "name": "W. Oosthuysen"}, {"authorId": "2111465222", "name": "Mohamed Sarvan"}, {"authorId": "2150284155", "name": "Carlos Calvo Gómez"}, {"authorId": "9818278", "name": "I. C. Rodríguez"}, {"authorId": "2064158163", "name": "A. Conde"}, {"authorId": "150012450", "name": "Á. C. Fillat"}, {"authorId": "1435987959", "name": "Guillem Cuatrecasas Cambra"}, {"authorId": "145752273", "name": "F. Moreno"}, {"authorId": "2098128763", "name": "L. D. T. Parreño"}, {"authorId": "41224045", "name": "J. D. Lista"}, {"authorId": "152656528", "name": "José Ramón Domínguez Escribano"}, {"authorId": "47546234", "name": "S. D. García"}, {"authorId": "2115206372", "name": "Javier E. Gonzalez"}, {"authorId": "2117021766", "name": "José F. Rodriguez"}, {"authorId": "2078233167", "name": "A. Arno"}, {"authorId": "5419570", "name": "R. G. Huelgas"}, {"authorId": "1974981559", "name": "J. Juanatey"}, {"authorId": "7477985", "name": "A. H. Mijares"}, {"authorId": "144253713", "name": "V. J. Diaz"}, {"authorId": "41329966", "name": "E. Gimeno"}, {"authorId": "2001153143", "name": "T. L. Morante"}, {"authorId": "49341250", "name": "M. Marazuela"}, {"authorId": "151146787", "name": "N. M. Claros"}, {"authorId": "2082173283", "name": "D. M. Puente"}, {"authorId": "79351046", "name": "Elena Mena Ribas"}, {"authorId": "2075317746", "name": "J. F. M. Torres"}, {"authorId": "4138055", "name": "P. M. Raya"}, {"authorId": "2111567270", "name": "Andreu Nubiola Calonge"}, {"authorId": "2076027987", "name": "Xavier Sánchez"}, {"authorId": "52076433", "name": "J. P. Izuel"}, {"authorId": "2250916196", "name": "V. Castilla"}, {"authorId": "2111729806", "name": "A. P. Pérez"}, {"authorId": "2072877239", "name": "Isabel Soto"}, {"authorId": "2095640951", "name": "Miguel Quesada Charneco"}, {"authorId": "2266290675", "name": "A. Simón"}, {"authorId": "2061076469", "name": "J. R. Màs"}, {"authorId": "80947816", "name": "A. R. Iraeta"}, {"authorId": "2110698755", "name": "M. R. Alvarez"}, {"authorId": "2056798840", "name": "I. Rodríguez"}, {"authorId": "80651833", "name": "J. S. Ruiz"}, {"authorId": "2209869888", "name": "A. González"}, {"authorId": "144145169", "name": "F. Madueño"}, {"authorId": "80877741", "name": "C. T. Serrano"}, {"authorId": "2111567070", "name": "Angels Ulied Armiñana"}, {"authorId": "2605361", "name": "E. Bachus"}, {"authorId": "2111563533", "name": "Katarina Berndtsson Blom"}, {"authorId": "46855465", "name": "Kent Eliasson"}, {"authorId": "144301231", "name": "P. Koskinen"}], "url": "https://www.semanticscholar.org/paper/95617ae716e49f4465e6cf72c984001a064e14f5", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "c29568d2c3c924ef1e6250fb132f1fb6ced16fbf", "title": "Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial.", "abstract": "BACKGROUND\nThe SELECT trial found semaglutide reduced major adverse cardiovascular events (MACE) in patients with overweight or obesity with cardiovascular disease but without diabetes. We report a prespecified analysis of the SELECT trial on the relationships between baseline adiposity measures, treatment-induced adiposity changes, and subsequent MACE risk.\n\n\nMETHODS\nPatients aged at least 45 years, with a BMI of at least 27 kg/m2 were enrolled in 41 countries (804 sites) and randomised 1:1 to once-weekly semaglutide 2·4 mg or placebo. The primary outcome was time to first MACE (composite of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke). Adiposity measures included weight and waist circumference. In this analysis, risk of MACE occurring after 20 weeks was assessed between patients by adiposity changes in the first 20 weeks and, in a separate analysis, all in-trial MACE were assessed between patients by adiposity changes over 104 weeks. This trial is registered with ClinicalTrials.gov, NCT03574597.\n\n\nFINDINGS\nSemaglutide significantly reduced MACE incidence compared with placebo among 17 604 patients enrolled in SELECT, with consistent benefits across all baseline weight and waist circumference categories. In the semaglutide group, analyses for linear trends showed lower baseline bodyweight and waist circumference were associated with lower incidence of MACE-an average 4% reduction in risk per 5 kg lower bodyweight (hazard ratio [HR] 0·96 [95% CI 0·94-0·99]; p=0·001) and per 5 cm smaller waist circumference (0·96 [0·93-0·99]; p=0·004). In the placebo group, lower baseline waist circumference (0·96 [0·94-0·99]; p=0·007), but not bodyweight (0·99 [0·97-1·01]; p=0·28), was associated with a lower MACE risk and weight loss was paradoxically associated with increased MACE risk. In those receiving semaglutide there was no linear trend linking weight loss at week 20 to subsequent MACE risk, but greater waist circumference reduction at week 20 was associated with lower subsequent MACE risk, and waist circumference reduction by week 104 was associated with lower in-trial risk of MACE. An estimated 33% of the observed benefit on MACE was mediated through waist circumference reduction (HR 0·86 [95% CI 0·77-0·97] after adjustment for time-varying changes in waist circumference).\n\n\nINTERPRETATION\nThe cardioprotective effects of semaglutide were independent of baseline adiposity and weight loss and had only a small association with waist circumference, suggesting some mechanisms for benefit beyond adiposity reduction.\n\n\nFUNDING\nNovo Nordisk.", "year": 2025, "publicationDate": "2025-10-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 82, "referenceCount": 23, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(25)01375-3.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2266235120", "name": "J. Deanfield"}, {"authorId": "2261931235", "name": "A. M. Lincoff"}, {"authorId": "2317289369", "name": "S. Kahn"}, {"authorId": "2266233481", "name": "S. Emerson"}, {"authorId": "3788935", "name": "I. Lingvay"}, {"authorId": "2274921165", "name": "Benjamin M. Scirica"}, {"authorId": "2306852764", "name": "J. Plutzky"}, {"authorId": "2266233127", "name": "Robert F. Kushner"}, {"authorId": "2306443625", "name": "Helen M. Colhoun"}, {"authorId": "2266896659", "name": "G. Hovingh"}, {"authorId": "2331536648", "name": "S. Stensen"}, {"authorId": "2307909174", "name": "P. E. Weeke"}, {"authorId": "49727989", "name": "O. Jeppesen"}, {"authorId": "2387562883", "name": "Rafael Bravo"}, {"authorId": "2345364372", "name": "Chau-Chung Wu"}, {"authorId": "2251718625", "name": "Issei Komuro"}, {"authorId": "2306277307", "name": "F. Santini"}, {"authorId": "4739225", "name": "J. Hjelmesæth"}, {"authorId": "2345036280", "name": "M. Urina-Triana"}, {"authorId": "2306020784", "name": "Silvio Buscemi"}, {"authorId": "2271593396", "name": "D. Ryan"}], "url": "https://www.semanticscholar.org/paper/c29568d2c3c924ef1e6250fb132f1fb6ced16fbf", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "b350a312f6d53b5b5219b2bd31e143c7b64ad51e", "title": "Variations between women and men in risk factors, treatments, cardiovascular disease incidence, and death in 27 high-income, middle-income, and low-income countries (PURE): a prospective cohort study.", "abstract": "BACKGROUND\nSome studies, mainly from high-income countries (HICs), report that women receive less care (investigations and treatments) for cardiovascular disease than do men and might have a higher risk of death. However, very few studies systematically report risk factors, use of primary or secondary prevention medications, incidence of cardiovascular disease, or death in populations drawn from the community. Given that most cardiovascular disease occurs in low-income and middle-income countries (LMICs), there is a need for comprehensive information comparing treatments and outcomes between women and men in HICs, middle-income countries, and low-income countries from community-based population studies.\n\n\nMETHODS\nIn the Prospective Urban Rural Epidemiological study (PURE), individuals aged 35-70 years from urban and rural communities in 27 countries were considered for inclusion. We recorded information on participants' sociodemographic characteristics, risk factors, medication use, cardiac investigations, and interventions. 168 490 participants who enrolled in the first two of the three phases of PURE were followed up prospectively for incident cardiovascular disease and death.\n\n\nFINDINGS\nFrom Jan 6, 2005 to May 6, 2019, 202 072 individuals were recruited to the study. The mean age of women included in the study was 50·8 (SD 9·9) years compared with 51·7 (10) years for men. Participants were followed up for a median of 9·5 (IQR 8·5-10·9) years. Women had a lower cardiovascular disease risk factor burden using two different risk scores (INTERHEART and Framingham). Primary prevention strategies, such as adoption of several healthy lifestyle behaviours and use of proven medicines, were more frequent in women than men. Incidence of cardiovascular disease (4·1 [95% CI 4·0-4·2] for women vs 6·4 [6·2-6·6] for men per 1000 person-years; adjusted hazard ratio [aHR] 0·75 [95% CI 0·72-0·79]) and all-cause death (4·5 [95% CI 4·4-4·7] for women vs 7·4 [7·2-7·7] for men per 1000 person-years; aHR 0·62 [95% CI 0·60-0·65]) were also lower in women. By contrast, secondary prevention treatments, cardiac investigations, and coronary revascularisation were less frequent in women than men with coronary artery disease in all groups of countries. Despite this, women had lower risk of recurrent cardiovascular disease events (20·0 [95% CI 18·2-21·7] versus 27·7 [95% CI 25·6-29·8] per 1000 person-years in men, adjusted hazard ratio 0·73 [95% CI 0·64-0·83]) and women had lower 30-day mortality after a new cardiovascular disease event compared with men (22% in women versus 28% in men; p<0·0001). Differences between women and men in treatments and outcomes were more marked in LMICs with little differences in HICs in those with or without previous cardiovascular disease.\n\n\nINTERPRETATION\nTreatments for cardiovascular disease are more common in women than men in primary prevention, but the reverse is seen in secondary prevention. However, consistently better outcomes are observed in women than in men, both in those with and without previous cardiovascular disease. Improving cardiovascular disease prevention and treatment, especially in LMICs, should be vigorously pursued in both women and men.\n\n\nFUNDING\nFull funding sources are listed at the end of the paper (see Acknowledgments).", "year": 2020, "publicationDate": "2020-05-20", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 264, "referenceCount": 48, "influentialCitationCount": 6, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Sociology", "source": "s2-fos-model"}], "authors": [{"authorId": "1413719128", "name": "M. Walli-Attaei"}, {"authorId": "145364229", "name": "P. Joseph"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "2595589", "name": "C. Chow"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "3658822", "name": "K. Alhabib"}, {"authorId": "145153062", "name": "K. Davletov"}, {"authorId": "7015123", "name": "A. Dans"}, {"authorId": "144226747", "name": "F. Lanas"}, {"authorId": "3947311", "name": "K. Yeates"}, {"authorId": "49255119", "name": "P. Poirier"}, {"authorId": "2591944", "name": "K. Teo"}, {"authorId": "5159307", "name": "A. Bahonar"}, {"authorId": "2106904342", "name": "F. Camilo"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "22580102", "name": "J. Didkowska"}, {"authorId": "152320647", "name": "V. Irazola"}, {"authorId": "40548968", "name": "R. Ismail"}, {"authorId": "144730173", "name": "M. Kaur"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "2111036755", "name": "Xiaoyun Liu"}, {"authorId": "9912516", "name": "M. Mańczuk"}, {"authorId": "145261794", "name": "J. Miranda"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "1422226007", "name": "Maritza Pérez-Mayorga"}, {"authorId": "6871361", "name": "A. Szuba"}, {"authorId": "4209461", "name": "L. Tsolekile"}, {"authorId": "31936743", "name": "R. Varma"}, {"authorId": "3532835", "name": "A. Yusufali"}, {"authorId": "47572577", "name": "R. Yusuf"}, {"authorId": "2113553874", "name": "Li Wei"}, {"authorId": "145276610", "name": "Sonia S Anand"}, {"authorId": "144636283", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/b350a312f6d53b5b5219b2bd31e143c7b64ad51e", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "9d271288de19e46b49e0726f884b14c0058261ea", "title": "Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70-100 years: a contemporary primary prevention cohort.", "abstract": "BACKGROUND\nFindings of historical studies suggest that elevated LDL cholesterol is not associated with increased risk of myocardial infarction and atherosclerotic cardiovascular disease in patients older than 70 years. We aimed to test this hypothesis in a contemporary population of individuals aged 70-100 years.\n\n\nMETHODS\nWe included in our analysis individuals (aged 20-100 years) from the Copenhagen General Population Study (CGPS) who did not have atherosclerotic cardiovascular disease or diabetes at baseline and who were not taking statins. Standard hospital assays were used to measure LDL cholesterol. We calculated hazard ratios (HRs) and absolute event rates for myocardial infarction and atherosclerotic cardiovascular disease, and we estimated the number needed to treat (NNT) in 5 years to prevent one event.\n\n\nFINDINGS\nBetween Nov 25, 2003, and Feb 17, 2015, 91 131 individuals were enrolled in CGPS. During mean 7·7 (SD 3·2) years of follow-up (to Dec 7, 2018), 1515 individuals had a first myocardial infarction and 3389 had atherosclerotic cardiovascular disease. Risk of myocardial infarction per 1·0 mmol/L increase in LDL cholesterol was augmented for the overall population (HR 1·34, 95% CI 1·27-1·41) and was amplified for all age groups, particularly those aged 70-100 years. Risk of atherosclerotic cardiovascular disease was also raised per 1·0 mmol/L increase in LDL cholesterol overall (HR 1·16, 95% CI 1·12-1·21) and in all age groups, particularly those aged 70-100 years. Risk of myocardial infarction was also increased with a 5·0 mmol/L or higher LDL cholesterol (ie, possible familial hypercholesterolaemia) versus less than 3·0 mmol/L in individuals aged 80-100 years (HR 2·99, 95% CI 1·71-5·23) and in those aged 70-79 years (1·82, 1·20-2·77). Myocardial infarction and atherosclerotic cardiovascular disease events per 1000 person-years for every 1·0 mmol/L increase in LDL cholesterol were highest in individuals aged 70-100 years, with number of events lower with younger age. The NNT in 5 years to prevent one myocardial infarction or atherosclerotic cardiovascular disease event if all people were given a moderate-intensity statin was lowest for individuals aged 70-100 years, with the NNT increasing with younger age.\n\n\nINTERPRETATION\nIn a contemporary primary prevention cohort, people aged 70-100 years with elevated LDL cholesterol had the highest absolute risk of myocardial infarction and atherosclerotic cardiovascular disease and the lowest estimated NNT in 5 years to prevent one event. Our data are important for preventive strategies aimed at reducing the burden of myocardial infarction and atherosclerotic cardiovascular disease in the growing population aged 70-100 years.\n\n\nFUNDING\nNone.", "year": 2020, "publicationDate": "2020-11-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 223, "referenceCount": 33, "influentialCitationCount": 6, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "39915377", "name": "M. Mortensen"}, {"authorId": "145641307", "name": "B. Nordestgaard"}], "url": "https://www.semanticscholar.org/paper/9d271288de19e46b49e0726f884b14c0058261ea", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "06a74606c9672b6a593fe3febe6db47f0141c171", "title": "Xanthine oxidase inhibition for cardiovascular disease prevention.", "abstract": null, "year": 2022, "publicationDate": "2022-10-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          1172-1173\n        ", "volume": "400 10359"}, "citationCount": 9, "referenceCount": 11, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673622017780/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "152780858", "name": "Atsushi Tanaka"}, {"authorId": "6943040", "name": "K. Node"}], "url": "https://www.semanticscholar.org/paper/06a74606c9672b6a593fe3febe6db47f0141c171", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "8a8355e757fd94f46af38057ed4e77e83d969aaa", "title": "The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study.", "abstract": null, "year": 2017, "publicationDate": "2017-12-16", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2643-2654\n        ", "volume": "390 10113"}, "citationCount": 1086, "referenceCount": 44, "influentialCitationCount": 23, "isOpenAccess": true, "openAccessPdfUrl": "https://www.pure.ed.ac.uk/ws/files/157166409/PURE_ID_37640768_AAM_PURE_PA_events_paper_Lancet_fourth_revision_clean.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "4389179", "name": "S. Lear"}, {"authorId": "48594869", "name": "Weihong Hu"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "7330295", "name": "D. Gasevic"}, {"authorId": "2059555282", "name": "D. Leong"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "1700076", "name": "A. Casanova"}, {"authorId": "4467378", "name": "S. Swaminathan"}, {"authorId": "2178673213", "name": "R. Anjana"}, {"authorId": "2152737494", "name": "Rajesh Kumar"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "2113553874", "name": "Li Wei"}, {"authorId": "2117111520", "name": "Wang Yang"}, {"authorId": "12092364", "name": "Chuangshi Wang"}, {"authorId": "2145488651", "name": "Huaxing Liu"}, {"authorId": "4651057", "name": "S. Nair"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "2111596937", "name": "Hany Swidon"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "4906293", "name": "N. Mohammadifard"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "6547067", "name": "K. Zatońska"}, {"authorId": "3831881", "name": "P. Serón"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "49255119", "name": "P. Poirier"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "144636283", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/8a8355e757fd94f46af38057ed4e77e83d969aaa", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "648222c740ddeb7ef67ab3bb837ae00462761355", "title": "Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study.", "abstract": null, "year": 2017, "publicationDate": null, "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2050-2062\n        ", "volume": "390 10107"}, "citationCount": 940, "referenceCount": 53, "influentialCitationCount": 39, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145319397", "name": "M. Dehghan"}, {"authorId": "5852860", "name": "A. Mente"}, {"authorId": "29456285", "name": "Xiaohe Zhang"}, {"authorId": "4467378", "name": "S. Swaminathan"}, {"authorId": "39310367", "name": "Wei Li"}, {"authorId": "2075337902", "name": "V. Mohan"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "47654405", "name": "Rajesh Kumar"}, {"authorId": "1380326663", "name": "E. Wentzel-Viljoen"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "2094397417", "name": "Leela Itty Amma"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "2111036755", "name": "Xiaoyun Liu"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "4906293", "name": "N. Mohammadifard"}, {"authorId": "2068203935", "name": "N. Gao"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "4572647", "name": "A. Ramli"}, {"authorId": "3831881", "name": "P. Serón"}, {"authorId": "2415812854", "name": "Yi Sun"}, {"authorId": "6871361", "name": "A. Szuba"}, {"authorId": "4209461", "name": "L. Tsolekile"}, {"authorId": "145572557", "name": "A. Wielgosz"}, {"authorId": "47572577", "name": "R. Yusuf"}, {"authorId": "37021165", "name": "A. Yusufali"}, {"authorId": "2591944", "name": "K. Teo"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "4317457", "name": "G. Dagenais"}, {"authorId": "2926304", "name": "S. Bangdiwala"}, {"authorId": "40146339", "name": "S. Islam"}, {"authorId": "145276610", "name": "Sonia S Anand"}, {"authorId": "144636283", "name": "S. Yusuf"}, {"authorId": "152132091", "name": "R. Diaz"}, {"authorId": "3632985", "name": "A. Orlandini"}, {"authorId": "119623638", "name": "B. Linetsky"}, {"authorId": "2111488835", "name": "S. Toscanelli"}, {"authorId": "11853116", "name": "G. Casaccia"}, {"authorId": "2111492387", "name": "JM Maini Cuneo"}, {"authorId": "48901309", "name": "O. Rahman"}, {"authorId": "67120686", "name": "R. Yusuf"}, {"authorId": "2125441399", "name": "A. Azad"}, {"authorId": "2101592551", "name": "K. Rabbani"}, {"authorId": "2253304251", "name": "HM Cherry"}, {"authorId": "73826729", "name": "A. Mannan"}, {"authorId": "153561558", "name": "I. Hassan"}, {"authorId": "47449718", "name": "Atlanta Talukdar"}, {"authorId": "2111481927", "name": "RB Tooheen"}, {"authorId": "2299944323", "name": "M. Khan"}, {"authorId": "35483813", "name": "M. Sintaha"}, {"authorId": "80351608", "name": "T. Choudhury"}, {"authorId": "153327188", "name": "R. Haque"}, {"authorId": "78374482", "name": "S. Parvin"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "2111128553", "name": "G.B. Oliveira"}, {"authorId": "66235143", "name": "C. Marcílio"}, {"authorId": "73373147", "name": "A. Mattos"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "144636283", "name": "S. Yusuf"}, {"authorId": "2617668", "name": "J. DeJesus"}, {"authorId": "2111500572", "name": "D. Agapay"}, {"authorId": "2111493566", "name": "T. Tongana"}, {"authorId": "134679092", "name": "R. Solano"}, {"authorId": "113759273", "name": "I. Kay"}, {"authorId": "50303861", "name": "S. Trottier"}, {"authorId": "2343965683", "name": "J. Rimac"}, {"authorId": "2095922740", "name": "W. ElSheikh"}, {"authorId": "104537735", "name": "L. Heldman"}, {"authorId": "2076609319", "name": "E. Ramezani"}, {"authorId": "4317457", "name": "G. Dagenais"}, {"authorId": "49255119", "name": "P. Poirier"}, {"authorId": "7485439", "name": "G. Turbide"}, {"authorId": "51375085", "name": "D. Auger"}, {"authorId": "2111484016", "name": "A. L. D. Bluts"}, {"authorId": "2111493795", "name": "MC Proulx"}, {"authorId": "116736392", "name": "M. Cayer"}, {"authorId": "14743912", "name": "N. Bonneville"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "7330295", "name": "D. Gasevic"}, {"authorId": "118864646", "name": "E. Corber"}, {"authorId": "49601129", "name": "V. D. Jong"}, {"authorId": "5719988", "name": "I. Vukmirovich"}, {"authorId": "145572557", "name": "A. Wielgosz"}, {"authorId": "97004084", "name": "G. Fodor"}, {"authorId": "88777760", "name": "A. Pipe"}, {"authorId": "2055887973", "name": "A. Shane"}, {"authorId": "144226747", "name": "F. Lanas"}, {"authorId": "3831881", "name": "P. Serón"}, {"authorId": "2067626838", "name": "S. Martínez"}, {"authorId": "104160606", "name": "A. Valdebenito"}, {"authorId": "84418640", "name": "M. Oliveros"}, {"authorId": "2113553874", "name": "Li Wei"}, {"authorId": "121421010", "name": "L. Lisheng"}, {"authorId": "8901915", "name": "C. Chunming"}, {"authorId": "12542376", "name": "W. Xingyu"}, {"authorId": "2069594601", "name": "Zhao Wenhua"}, {"authorId": "91189237", "name": "Z. Hongye"}, {"authorId": "2058203486", "name": "Jia Xuan"}, {"authorId": "2053703770", "name": "Hu Bo"}, {"authorId": "2068062567", "name": "Sun Yi"}, {"authorId": "2062644338", "name": "Bo Jian"}, {"authorId": "120854642", "name": "Zhao Xiuwen"}, {"authorId": "66033484", "name": "Chang Xiaohong"}, {"authorId": "2053904845", "name": "Chen Tao"}, {"authorId": "2068963374", "name": "Chen Hui"}, {"authorId": "2057188156", "name": "Deng Qing"}, {"authorId": "66967619", "name": "Chen Xiaoru"}, {"authorId": "2111481981", "name": "He Xinye"}, {"authorId": "49173088", "name": "Li Jian"}, {"authorId": "2106131920", "name": "Li Juan"}, {"authorId": "2112161830", "name": "Liu Xu"}, {"authorId": "72157098", "name": "R. Bing"}, {"authorId": "2118430986", "name": "Wang Wei"}, {"authorId": "2117111520", "name": "Wang Yang"}, {"authorId": "2067671201", "name": "Yang Jun"}, {"authorId": "2105569266", "name": "Z. yi"}, {"authorId": "11230852", "name": "Zhu Manlu"}, {"authorId": "13063138", "name": "L. Fanghong"}, {"authorId": "2095648669", "name": "Wu Jianfang"}, {"authorId": "115353485", "name": "Li Yindong"}, {"authorId": "2282118684", "name": "Hou Yan"}, {"authorId": "66713394", "name": "Zhang Liangqing"}, {"authorId": "72190946", "name": "Guo Baoxia"}, {"authorId": "2021063006", "name": "Li Xiaoyang"}, {"authorId": "2820488", "name": "Zhang Shiying"}, {"authorId": "2080506353", "name": "Bian Rongwen"}, {"authorId": "2072044871", "name": "Tian Xiuzhen"}, {"authorId": "2152289079", "name": "Li Dong"}, {"authorId": "2064328406", "name": "C. Di"}, {"authorId": "49814303", "name": "W. Jianguo"}, {"authorId": "117604304", "name": "Xiao Yize"}, {"authorId": "2095076082", "name": "Liu Tianlu"}, {"authorId": "2107093009", "name": "Zhang Peng"}, {"authorId": "81844993", "name": "Dong Changlin"}, {"authorId": "2105165365", "name": "Li Ning"}, {"authorId": "84278747", "name": "Mao Xiaolan"}, {"authorId": "2027975161", "name": "Y. Yuqing"}, {"authorId": "7422353", "name": "Lei Rensheng"}, {"authorId": "7888362", "name": "Fu Minfan"}, {"authorId": "2026244652", "name": "H. Jing"}, {"authorId": "86910370", "name": "Liu-Yan Yu"}, {"authorId": "72304377", "name": "Xin Xiaojie"}, {"authorId": "36006016", "name": "Z. Qiang"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "2067528899", "name": "P. López"}, {"authorId": "2107196725", "name": "R. Garcia"}, {"authorId": "2111493339", "name": "Lja Jurado"}, {"authorId": "1380326202", "name": "D. Gómez-Arbeláez"}, {"authorId": "144953769", "name": "J. Arguello"}, {"authorId": "10179590", "name": "R. Dueñas"}, {"authorId": "2348898363", "name": "S. Silva"}, {"authorId": "2111482150", "name": "LP Pradilla"}, {"authorId": "2064399508", "name": "F. Ramírez"}, {"authorId": "121920112", "name": "D. Molina"}, {"authorId": "80637593", "name": "C. Cure-Cure"}, {"authorId": "2110827358", "name": "M. Pérez"}, {"authorId": "40501082", "name": "E. Hernandez"}, {"authorId": "39607343", "name": "E. Arcos"}, {"authorId": "107847138", "name": "S. Fernández"}, {"authorId": "123318045", "name": "C. Narváez"}, {"authorId": "2058696132", "name": "J. Paez"}, {"authorId": "15570027", "name": "A. Sotomayor"}, {"authorId": "145173162", "name": "H. García"}, {"authorId": "145282562", "name": "G. Sánchez"}, {"authorId": "153216760", "name": "T. David"}, {"authorId": "2071808055", "name": "Á. Rico"}, {"authorId": "9000040", "name": "P. Mony"}, {"authorId": "145463819", "name": "M. Vaz"}, {"authorId": "6737525", "name": "A. Bharathi"}, {"authorId": "4467378", "name": "S. Swaminathan"}, {"authorId": "2289476981", "name": "K. Kurpad"}, {"authorId": "11001355", "name": "K. Jayachitra"}, {"authorId": "2118654510", "name": "N. Kumar"}, {"authorId": "2110597660", "name": "H. Hospital"}, {"authorId": "2056064008", "name": "V. Mohan"}, {"authorId": "35112328", "name": "M. Deepa"}, {"authorId": "1605065927", "name": "K. Parthiban"}, {"authorId": "49474576", "name": "M. Anitha"}, {"authorId": "32391694", "name": "S. Hemavathy"}, {"authorId": "117002560", "name": "T. Rahulashankiruthiyayan"}, {"authorId": "144820959", "name": "D. Anitha"}, {"authorId": "47376766", "name": "K. Sridevi"}, {"authorId": "67039928", "name": "R. Gupta"}, {"authorId": "152734334", "name": "R. Panwar"}, {"authorId": "4397858", "name": "I. Mohan"}, {"authorId": "46713170", "name": "P. Rastogi"}, {"authorId": "1441533432", "name": "S. Rastogi"}, {"authorId": "14628245", "name": "R. Bhargava"}, {"authorId": "49165677", "name": "R. Kumar"}, {"authorId": "97592129", "name": "J. S. Thakur"}, {"authorId": "48494603", "name": "Badri N. Patro"}, {"authorId": "145775997", "name": "P. Lakshmi"}, {"authorId": "2113791139", "name": "R. Mahajan"}, {"authorId": "49076024", "name": "P. Chaudary"}, {"authorId": "46838873", "name": "V. Kutty"}, {"authorId": "122013527", "name": "K. Vijayakumar"}, {"authorId": "2583527", "name": "K. Ajayan"}, {"authorId": "81831882", "name": "G. Rajasree"}, {"authorId": "46377525", "name": "A. Renjini"}, {"authorId": "6344925", "name": "A. Deepu"}, {"authorId": "1858990", "name": "B. Sandhya"}, {"authorId": "1397399234", "name": "S. Asha"}, {"authorId": "2111483436", "name": "H. Soumya"}, {"authorId": "4924433", "name": "R. Kelishadi"}, {"authorId": "5159307", "name": "A. Bahonar"}, {"authorId": "77931118", "name": "N. Mohammadifard"}, {"authorId": "34855542", "name": "H. Heidari"}, {"authorId": "1977461", "name": "K. Yusoff"}, {"authorId": "2316185795", "name": "T. Ismail"}, {"authorId": "79253065", "name": "Kk Ng"}, {"authorId": "2143783115", "name": "A. Devi"}, {"authorId": "144705206", "name": "N. Nasir"}, {"authorId": "144954985", "name": "M. Yasin"}, {"authorId": "6326737", "name": "M. Miskan"}, {"authorId": "2272012830", "name": "E. Rahman"}, {"authorId": "2111495272", "name": "Mkm Arsad"}, {"authorId": "39632274", "name": "F. Ariffin"}, {"authorId": "69015174", "name": "S. Razak"}, {"authorId": "29423186", "name": "F. Majid"}, {"authorId": "3583229", "name": "N. Bakar"}, {"authorId": "6582237", "name": "M. Yacob"}, {"authorId": "96739907", "name": "N. Zainon"}, {"authorId": "51141526", "name": "R. Salleh"}, {"authorId": "2111483651", "name": "M. Ramli"}, {"authorId": "121762347", "name": "Nammous Halim"}, {"authorId": "2111495203", "name": "SR Norlizan"}, {"authorId": "2276577481", "name": "N. Ghazali"}, {"authorId": "152735556", "name": "M. Arshad"}, {"authorId": "31683145", "name": "R. Razali"}, {"authorId": "2107404794", "name": "S. Ali"}, {"authorId": "2111492575", "name": "HR Othman"}, {"authorId": "2111493424", "name": "Cwjcw Hafar"}, {"authorId": "83606734", "name": "A. Pit"}, {"authorId": "6533158", "name": "N. Danuri"}, {"authorId": "4648748", "name": "F. Basir"}, {"authorId": "2297381102", "name": "S. M. Shahrul Nizan Shikh Zahari"}, {"authorId": "1753612851", "name": "H. Abdullah"}, {"authorId": "2111493352", "name": "MA Arippin"}, {"authorId": "115672260", "name": "Nawfal A. Zakaria"}, {"authorId": "6163324", "name": "I. Noorhassim"}, {"authorId": "2268745231", "name": "M. Hasni"}, {"authorId": "66604835", "name": "M. Azmi"}, {"authorId": "88698243", "name": "Michael J. Zaleha"}, {"authorId": "2111476874", "name": "KY Hazdi"}, {"authorId": "13985568", "name": "A. Rizam"}, {"authorId": "2111492558", "name": "W. Sazman"}, {"authorId": "100882129", "name": "A. Azman"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "4604722", "name": "U. Khammash"}, {"authorId": "150018093", "name": "A. Khatib"}, {"authorId": "1914010207", "name": "R. Giacaman"}, {"authorId": "89779342", "name": "R. Iqbal"}, {"authorId": "143872469", "name": "A. Afridi"}, {"authorId": "1412487840", "name": "R. Khawaja"}, {"authorId": "2057543125", "name": "A. Raza"}, {"authorId": "6511263", "name": "K. Kazmi"}, {"authorId": "3717053", "name": "W. Zatoński"}, {"authorId": "6871361", "name": "A. Szuba"}, {"authorId": "6547067", "name": "K. Zatońska"}, {"authorId": "30319088", "name": "R. Ilow"}, {"authorId": "5639874", "name": "M. Ferus"}, {"authorId": "1380327267", "name": "B. Regulska-Ilow"}, {"authorId": "6382221", "name": "D. Różańska"}, {"authorId": "152183912", "name": "M. Wołyniec"}, {"authorId": "2111476845", "name": "Alkamel"}, {"authorId": "1951714178", "name": "M. Ali"}, {"authorId": "2068133197", "name": "M. A. Kruger"}, {"authorId": "2085477719", "name": "H. Voster"}, {"authorId": "2070114838", "name": "A. Schutte"}, {"authorId": "1380326663", "name": "E. Wentzel-Viljoen"}, {"authorId": "121073108", "name": "F. Eloff"}, {"authorId": "145889139", "name": "H. D. Ridder"}, {"authorId": "40701046", "name": "H. Moss"}, {"authorId": "116450755", "name": "J. Potgieter"}, {"authorId": "143873488", "name": "A. Roux"}, {"authorId": "144547942", "name": "M. Watson"}, {"authorId": "104683208", "name": "G. D. Wet"}, {"authorId": "3666170", "name": "A. Olckers"}, {"authorId": "32110195", "name": "J. Jerling"}, {"authorId": "143831612", "name": "M. Pieters"}, {"authorId": "108238353", "name": "T. Hoekstra"}, {"authorId": "2942584", "name": "T. Puoane"}, {"authorId": "6889172", "name": "E. Igumbor"}, {"authorId": "4209461", "name": "L. Tsolekile"}, {"authorId": "2053355120", "name": "D. Sanders"}, {"authorId": "47392549", "name": "P. Naidoo"}, {"authorId": "14485415", "name": "N. Steyn"}, {"authorId": "6428915", "name": "N. Peer"}, {"authorId": "40636311", "name": "B. Mayosi"}, {"authorId": "2090939032", "name": "B. Rayner"}, {"authorId": "7474774", "name": "V. Lambert"}, {"authorId": "1768385072", "name": "N. Levitt"}, {"authorId": "1380326761", "name": "T. Kolbe-Alexander"}, {"authorId": "4259272", "name": "L. Ntyintyane"}, {"authorId": "96540094", "name": "G. Hughes"}, {"authorId": "48349626", "name": "R. Swart"}, {"authorId": "144795568", "name": "J. Fourie"}, {"authorId": "2329354024", "name": "M. Muzigaba"}, {"authorId": "2111482791", "name": "S. Xapa"}, {"authorId": "2111492686", "name": "N. Gobile"}, {"authorId": "32825404", "name": "K. Ndayi"}, {"authorId": "2111482139", "name": "B. Jwili"}, {"authorId": "2111492695", "name": "K. Ndibaza"}, {"authorId": "13639249", "name": "B. Egbujie"}, {"authorId": "2057942195", "name": "A. Rosengren"}, {"authorId": "25615980", "name": "K. Boström"}, {"authorId": "34770142", "name": "A. Gustavsson"}, {"authorId": "2054271027", "name": "M. Andreasson"}, {"authorId": "2111494347", "name": "M. Snällman"}, {"authorId": "2111482744", "name": "L. Wirdemann"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "5020564", "name": "N. Imeryuz"}, {"authorId": "46891464", "name": "Y. Altuntas"}, {"authorId": "4213309", "name": "S. Gulec"}, {"authorId": "8478460", "name": "A. Temizhan"}, {"authorId": "5469760", "name": "K. Karşıdağ"}, {"authorId": "2111492506", "name": "K. Calik"}, {"authorId": "2111494020", "name": "A. Akalin"}, {"authorId": "2111482141", "name": "O. Caklili"}, {"authorId": "2111476446", "name": "MV Keskinler"}, {"authorId": "2111482102", "name": "AN Erbakan"}, {"authorId": "2111439567", "name": "A. Yusufali"}, {"authorId": "5197438", "name": "W. Almahmeed"}, {"authorId": "1403239107", "name": "H. Swidan"}, {"authorId": "2111476139", "name": "EA Darwish"}, {"authorId": "3106048", "name": "Araz Hashemi"}, {"authorId": "1413225304", "name": "N. Al-khaja"}, {"authorId": "2111482713", "name": "J. Muscat-Baron"}, {"authorId": "2109162840", "name": "Shuaib Ahmed"}, {"authorId": "2111475964", "name": "TM Mamdouh"}, {"authorId": "2111493709", "name": "W. Darwish"}, {"authorId": "2111482910", "name": "Mhs Abdelmotagali"}, {"authorId": "2111491926", "name": "SA Omer Awed"}, {"authorId": "2111493801", "name": "GA Movahedi"}, {"authorId": "2065253815", "name": "F. Hussain"}, {"authorId": "1486132430", "name": "H. Shaibani"}, {"authorId": "2111482725", "name": "Rim Gharabou"}, {"authorId": "2353201326", "name": "D. Youssef"}, {"authorId": "2111495541", "name": "Azs Nawati"}, {"authorId": "2111494192", "name": "Zar Abu Salah"}, {"authorId": "2239921477", "name": "R. Abdalla"}, {"authorId": "2111476234", "name": "SM Al Shuwaihi"}, {"authorId": "1484194461", "name": "M. Omairi"}, {"authorId": "2111493956", "name": "OD Cadigal"}, {"authorId": "2111481752", "name": "R. S. Alejandrino"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "3953743", "name": "Lenon Gwaunza"}, {"authorId": "5306803", "name": "G. Terera"}, {"authorId": "15375191", "name": "C. Mahachi"}, {"authorId": "11793118", "name": "P. Murambiwa"}, {"authorId": "117722785", "name": "T. Machiweni"}, {"authorId": "3701900", "name": "R. Mapanga"}], "url": "https://www.semanticscholar.org/paper/648222c740ddeb7ef67ab3bb837ae00462761355", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "b10a21f43cb8d892cc7fb9f4e56d4c51e2f97386", "title": "The rise and fall of aspirin in the primary prevention of cardiovascular disease.", "abstract": "Aspirin is one of the most frequently used drugs worldwide and is generally considered effective for the secondary prevention of cardiovascular disease. By contrast, the role of aspirin in primary prevention of cardiovascular disease is controversial. Early trials evaluating aspirin for primary prevention, done before the turn of the millennium, suggested reductions in myocardial infarction and stroke (although not mortality), and an increased risk of bleeding. In an effort to balance the risks and benefits of aspirin, international guidelines on primary prevention of cardiovascular disease have typically recommended aspirin only when a substantial 10-year risk of cardiovascular events exists. However, in 2018, three large randomised clinical trials of aspirin for the primary prevention of cardiovascular disease showed little or no benefit and have even suggested net harm. In this narrative Review, we reappraise the role of aspirin in primary prevention of cardiovascular disease, contextualising data from historical and contemporary trials.", "year": 2019, "publicationDate": "2019-05-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2155-2167\n        ", "volume": "393 10186"}, "citationCount": 155, "referenceCount": 102, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "47124619", "name": "Inbar Raber"}, {"authorId": "2512752", "name": "Cian P. McCarthy"}, {"authorId": "5942717", "name": "M. Vaduganathan"}, {"authorId": "3021453", "name": "Deepak L. Bhatt"}, {"authorId": "2010562", "name": "J. McEvoy"}], "url": "https://www.semanticscholar.org/paper/b10a21f43cb8d892cc7fb9f4e56d4c51e2f97386", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "aeff00c2a94c88e135c2f14584acb7b95bc77d48", "title": "Antiplatelet therapy for secondary prevention of cardiovascular disease: challenging the certainties.", "abstract": null, "year": 2021, "publicationDate": "2021-05-14", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 10, "referenceCount": 10, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "13268346", "name": "M. Chiarito"}, {"authorId": "3612460", "name": "G. Stefanini"}], "url": "https://www.semanticscholar.org/paper/aeff00c2a94c88e135c2f14584acb7b95bc77d48", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "cba910cde24636b093c7e526d35d334bb0289e30", "title": "World Heart Day 2021: COVID-19, digital health, and tackling cardiovascular disease", "abstract": null, "year": 2021, "publicationDate": "2021-09-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "1467 - 1468", "volume": "398"}, "citationCount": 8, "referenceCount": 19, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673621021449/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "144618228", "name": "F. Pinto"}, {"authorId": "7007417", "name": "D. Piñeiro"}, {"authorId": "2215115", "name": "A. Banerjee"}, {"authorId": "2662985", "name": "P. Perel"}, {"authorId": "2129297052", "name": "Borjana Pervan"}, {"authorId": "40282757", "name": "J. Eiselé"}], "url": "https://www.semanticscholar.org/paper/cba910cde24636b093c7e526d35d334bb0289e30", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "e4ad7de4afd3a8c4b643fa7e6d2bb7892e83ca34", "title": "Polypills with or without aspirin for primary prevention of cardiovascular disease.", "abstract": null, "year": 2021, "publicationDate": "2021-08-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 2, "referenceCount": 12, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://ora.ox.ac.uk/objects/uuid:8f3d815f-8c9a-403f-a25e-11a60e6c950b", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145342171", "name": "J. Mant"}, {"authorId": "2095500530", "name": "Richard McManus"}], "url": "https://www.semanticscholar.org/paper/e4ad7de4afd3a8c4b643fa7e6d2bb7892e83ca34", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "7cfd02ed842472de15cb76834fae21c04e2d078b", "title": "Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial", "abstract": "Summary Background The use of aspirin in the primary prevention of cardiovascular events remains controversial. We aimed to assess the efficacy and safety of aspirin versus placebo in patients with a moderate estimated risk of a first cardiovascular event. Methods ARRIVE is a randomised, double-blind, placebo-controlled, multicentre study done in seven countries. Eligible patients were aged 55 years (men) or 60 years (women) and older and had an average cardiovascular risk, deemed to be moderate on the basis of the number of specific risk factors. We excluded patients at high risk of gastrointestinal bleeding or other bleeding, or diabetes. Patients were randomly assigned (1:1) with a computer-generated randomisation code to receive enteric-coated aspirin tablets (100 mg) or placebo tablets, once daily. Patients, investigators, and others involved in treatment or data analysis were masked to treatment allocation. The primary efficacy endpoint was a composite outcome of time to first occurrence of cardiovascular death, myocardial infarction, unstable angina, stroke, or transient ischaemic attack. Safety endpoints were haemorrhagic events and incidence of other adverse events, and were analysed in the intention-to-treat population. This study is registered with ClinicalTrials. gov, number NCT00501059. Findings Between July 5, 2007, and Nov 15, 2016, 12 546 patients were enrolled and randomly assigned to receive aspirin (n=6270) or placebo (n=6276) at 501 study sites. Median follow-up was 60 months. In the intention-to-treat analysis, the primary endpoint occurred in 269 (4·29%) patients in the aspirin group versus 281 (4·48%) patients in the placebo group (hazard ratio [HR] 0·96; 95% CI 0·81–1·13; p=0·6038). Gastrointestinal bleeding events (mostly mild) occurred in 61 (0·97%) patients in the aspirin group versus 29 (0·46%) in the placebo group (HR 2·11; 95% CI 1·36–3·28; p=0·0007). The overall incidence rate of serious adverse events was similar in both treatment groups (n=1266 [20·19%] in the aspirin group vs n=1311 [20·89%] in the placebo group. The overall incidence of adverse events was similar in both treatment groups (n=5142 [82·01%] vs n=5129 [81·72%] in the placebo group). The overall incidence of treatment-related adverse events was low (n=1050 [16·75%] vs n=850 [13·54%] in the placebo group; p<0·0001). There were 321 documented deaths in the intention-to-treat population (n=160 [2·55%] vs n=161 [2·57%] of 6276 patients in the placebo group). Interpretation The event rate was much lower than expected, which is probably reflective of contemporary risk management strategies, making the study more representative of a low-risk population. The role of aspirin in primary prevention among patients at moderate risk could therefore not be addressed. Nonetheless, the findings with respect to aspirin’s effects are consistent with those observed in the previously published low-risk primary prevention studies. Funding Bayer.", "year": 2018, "publicationDate": "2018-08-26", "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "1036 - 1046", "volume": "392"}, "citationCount": 743, "referenceCount": 33, "influentialCitationCount": 28, "isOpenAccess": true, "openAccessPdfUrl": "https://www.ncbi.nlm.nih.gov/pmc/articles/7255888", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2302239804", "name": "J. Gaziano"}, {"authorId": "2302239813", "name": "J. M. Gaziano"}, {"authorId": "2302239783", "name": "J. Gaziano"}, {"authorId": "50296885", "name": "C. Brotons"}, {"authorId": "2275423790", "name": "Rosa Coppolecchia"}, {"authorId": "3414773", "name": "C. Cricelli"}, {"authorId": "4050457", "name": "H. Darius"}, {"authorId": "5238126", "name": "P. Gorelick"}, {"authorId": "145767517", "name": "G. Howard"}, {"authorId": "2250493067", "name": "T. A. Pearson"}, {"authorId": "2293943476", "name": "Peter M. Rothwell"}, {"authorId": "2247626227", "name": "Luis M. Ruilope"}, {"authorId": "5484307", "name": "M. Tendera"}, {"authorId": "144045929", "name": "G. Tognoni"}], "url": "https://www.semanticscholar.org/paper/7cfd02ed842472de15cb76834fae21c04e2d078b", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "d3d68e4dde204e374e477d2095539847759186fc", "title": "Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study.", "abstract": null, "year": 2017, "publicationDate": null, "publicationTypes": ["Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2037-2049\n        ", "volume": "390 10107"}, "citationCount": 529, "referenceCount": 51, "influentialCitationCount": 15, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673617322535/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Agricultural and Food Sciences", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145198166", "name": "Victoria Miller"}, {"authorId": "5852860", "name": "A. Mente"}, {"authorId": "145319397", "name": "M. Dehghan"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "29456285", "name": "Xiaohe Zhang"}, {"authorId": "4467378", "name": "S. Swaminathan"}, {"authorId": "4317457", "name": "G. Dagenais"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "2378756982", "name": "V. Mohan"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "2926304", "name": "S. Bangdiwala"}, {"authorId": "4824543", "name": "A. Schutte"}, {"authorId": "1380326663", "name": "E. Wentzel-Viljoen"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "46891464", "name": "Y. Altuntas"}, {"authorId": "1977461", "name": "K. Yusoff"}, {"authorId": "35291134", "name": "Noorhassim Ismail"}, {"authorId": "6428915", "name": "N. Peer"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "145092558", "name": "R. Diaz"}, {"authorId": "48901309", "name": "O. Rahman"}, {"authorId": "4906293", "name": "N. Mohammadifard"}, {"authorId": "6112849", "name": "F. Lana"}, {"authorId": "6547067", "name": "K. Zatońska"}, {"authorId": "145572557", "name": "A. Wielgosz"}, {"authorId": "37021165", "name": "A. Yusufali"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "145052115", "name": "A. Rosengren"}, {"authorId": "4693150", "name": "V. Kutty"}, {"authorId": "39310367", "name": "Wei Li"}, {"authorId": "2144128878", "name": "Jiankang Liu"}, {"authorId": "2111036755", "name": "Xiaoyun Liu"}, {"authorId": "144704400", "name": "Lu Yin"}, {"authorId": "2591944", "name": "K. Teo"}, {"authorId": "145276610", "name": "Sonia S Anand"}, {"authorId": "144636283", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/d3d68e4dde204e374e477d2095539847759186fc", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "e7b7e36fcd8998653b950edf8b7808226d21bfcf", "title": "Excess mortality and cardiovascular disease in type 1 diabetes in relation to age at onset: a nationwide study of 27,195 young adults with diabetes", "abstract": "Background We compared individuals with type 1 diabetes (T1D) to matched controls in order to examine how age at diagnosis of T1D relates to excess mortality and cardiovascular (CV) risk. Methods We studied 27,195 persons with T1D in the Swedish National Diabetes Registry, and 135,178 matched controls from the general population. Using Cox regression, and with adjustment for diabetes duration, we estimated excess risk of all-cause mortality, CV mortality, non-CV mortality, acute myocardial infarction (AMI), stroke, CVD (AMI and stroke), coronary heart disease (CHD), heart failure (HF) and atrial fibrillation (AF). Individuals with T1D were categorized into five groups, according to age at diagnosis: 0–9, 10–14, 15–19, 20–24 and 25–30 years. Findings A total of 27,195 persons with T1D and 135,178 controls were included; 924 persons with T1D and 1,405 controls died during follow-up, of which median was 10 years. Patients who developed T1D at 0–10 years of age displayed hazard ratios (95% CI) of 4.11 (3.24–5.22) for death, 7.38 (3.65–14.94) for CV death, 11.44 (7.95–16.44) for CVD, 30.50 (19.98–46.57) for CHD, 30.95 (17.59–54.45) for AMI, 6.45 (4.04–10.31) for stroke, 12.90 (7.30–22.51) for HF and 1.17 (0.62–2.20) for AF. Corresponding figures for those who developed T1D in the age-range 26–30 were 2.83 (2.38–3.37) for death, 3.64 (2.34–5.66) for CV death, 3.85 (3.05–4.87) for CVD, 6.08 (4.71–7.84) for CHD, 5.77 (4.08–8.16) for AMI, 3.22 (2.35–4.42) for stroke and 5.07 (3.55–7.22) for HF; hence excess risk differed up to 5-fold across the diagnosis age. The highest overall incidence rate, noted for all-cause mortality, was 1.9 (95% CI 1.71 to 2.11) per 100.000 person-years for patients with T1D. Developing T1D before 10 years of age resulted in a loss of 17.7 and 14.2 life years for women and men, respectively, whereas years lost were 10.1 and 9.4 in those diagnosed between 26-30 years of age. Interpretation Age at onset of type 1 diabetes is an important determinant of survival, as well as all cardiovascular outcomes, with highest excess risk in females. Greater focus on cardioprotection maybe warranted in those with early onset T1D. Funding Swedish Heart and Lung Foundation", "year": 2018, "publicationDate": "2018-08-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "477 - 486", "volume": "392"}, "citationCount": 612, "referenceCount": 38, "influentialCitationCount": 25, "isOpenAccess": true, "openAccessPdfUrl": "https://ore.exeter.ac.uk/repository/bitstream/10871/34677/5/Manuscript.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2251590998", "name": "A. Rawshani"}, {"authorId": "50179379", "name": "N. Sattar"}, {"authorId": "48621520", "name": "S. Franzén"}, {"authorId": "152770448", "name": "A. Rawshani"}, {"authorId": "3934374", "name": "A. Hattersley"}, {"authorId": "144543298", "name": "A. Svensson"}, {"authorId": "2505547", "name": "B. Eliasson"}, {"authorId": "4137142", "name": "S. Gudbjörnsdottir"}], "url": "https://www.semanticscholar.org/paper/e7b7e36fcd8998653b950edf8b7808226d21bfcf", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "76c15dc9402b36c123890225ce16e681ec7ee146", "title": "Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial.", "abstract": "BACKGROUND\nSemaglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events (MACE) in people with overweight or obesity, but the effects of this drug on outcomes in patients with atherosclerotic cardiovascular disease and heart failure are unknown. We report a prespecified analysis of the effect of once-weekly subcutaneous semaglutide 2·4 mg on ischaemic and heart failure cardiovascular outcomes. We aimed to investigate if semaglutide was beneficial in patients with atherosclerotic cardiovascular disease with a history of heart failure compared with placebo; if there was a difference in outcome in patients designated as having heart failure with preserved ejection fraction compared with heart failure with reduced ejection fraction; and if the efficacy and safety of semaglutide in patients with heart failure was related to baseline characteristics or subtype of heart failure.\n\n\nMETHODS\nThe SELECT trial was a randomised, double-blind, multicentre, placebo-controlled, event-driven phase 3 trial in 41 countries. Adults aged 45 years and older, with a BMI of 27 kg/m2 or greater and established cardiovascular disease were eligible for the study. Patients were randomly assigned (1:1) with a block size of four using an interactive web response system in a double-blind manner to escalating doses of once-weekly subcutaneous semaglutide over 16 weeks to a target dose of 2·4 mg, or placebo. In a prespecified analysis, we examined the effect of semaglutide compared with placebo in patients with and without a history of heart failure at enrolment, subclassified as heart failure with preserved ejection fraction, heart failure with reduced ejection fraction, or unclassified heart failure. Endpoints comprised MACE (a composite of non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death); a composite heart failure outcome (cardiovascular death or hospitalisation or urgent hospital visit for heart failure); cardiovascular death; and all-cause death. The study is registered with ClinicalTrials.gov, NCT03574597.\n\n\nFINDINGS\nBetween Oct 31, 2018, and March 31, 2021, 17 604 patients with a mean age of 61·6 years (SD 8·9) and a mean BMI of 33·4 kg/m2 (5·0) were randomly assigned to receive semaglutide (8803 [50·0%] patients) or placebo (8801 [50·0%] patients). 4286 (24·3%) of 17 604 patients had a history of investigator-defined heart failure at enrolment: 2273 (53·0%) of 4286 patients had heart failure with preserved ejection fraction, 1347 (31·4%) had heart failure with reduced ejection fraction, and 666 (15·5%) had unclassified heart failure. Baseline characteristics were similar between patients with and without heart failure. Patients with heart failure had a higher incidence of clinical events. Semaglutide improved all outcome measures in patients with heart failure at random assignment compared with those without heart failure (hazard ratio [HR] 0·72, 95% CI 0·60-0·87 for MACE; 0·79, 0·64-0·98 for the heart failure composite endpoint; 0·76, 0·59-0·97 for cardiovascular death; and 0·81, 0·66-1·00 for all-cause death; all pinteraction>0·19). Treatment with semaglutide resulted in improved outcomes in both the heart failure with reduced ejection fraction (HR 0·65, 95% CI 0·49-0·87 for MACE; 0·79, 0·58-1·08 for the composite heart failure endpoint) and heart failure with preserved ejection fraction groups (0·69, 0·51-0·91 for MACE; 0·75, 0·52-1·07 for the composite heart failure endpoint), although patients with heart failure with reduced ejection fraction had higher absolute event rates than those with heart failure with preserved ejection fraction. For MACE and the heart failure composite, there were no significant differences in benefits across baseline age, sex, BMI, New York Heart Association status, and diuretic use. Serious adverse events were less frequent with semaglutide versus placebo, regardless of heart failure subtype.\n\n\nINTERPRETATION\nIn patients with atherosclerotic cardiovascular diease and overweight or obesity, treatment with semaglutide 2·4 mg reduced MACE and composite heart failure endpoints compared with placebo in those with and without clinical heart failure, regardless of heart failure subtype. Our findings could facilitate prescribing and result in improved clinical outcomes for this patient group.\n\n\nFUNDING\nNovo Nordisk.", "year": 2024, "publicationDate": "2024-08-01", "publicationTypes": ["ClinicalTrial", "Study", "JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          773-786\n        ", "volume": "404 10454"}, "citationCount": 197, "referenceCount": 23, "influentialCitationCount": 19, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/s0140-6736(24)01498-3", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2266235120", "name": "J. Deanfield"}, {"authorId": "2249887142", "name": "Subodh Verma"}, {"authorId": "6600728", "name": "B. Scirica"}, {"authorId": "2247459239", "name": "S. Kahn"}, {"authorId": "2266233481", "name": "S. Emerson"}, {"authorId": "2368323649", "name": "Donna H Ryan"}, {"authorId": "3788935", "name": "I. Lingvay"}, {"authorId": "2306443625", "name": "Helen M. Colhoun"}, {"authorId": "2306852764", "name": "J. Plutzky"}, {"authorId": "2261598183", "name": "Mikhail N. Kosiborod"}, {"authorId": "2266896659", "name": "G. Hovingh"}, {"authorId": "2196300394", "name": "S. Hardt-Lindberg"}, {"authorId": "2007057568", "name": "O. Frenkel"}, {"authorId": "2307909174", "name": "P. E. Weeke"}, {"authorId": "2256897269", "name": "S. Rasmussen"}, {"authorId": "2249800203", "name": "A. Goudev"}, {"authorId": "2314394441", "name": "Chim C. Lang"}, {"authorId": "2345036280", "name": "M. Urina-Triana"}, {"authorId": "3907559", "name": "M. Pietilä"}, {"authorId": "2261931235", "name": "A. M. Lincoff"}, {"authorId": "2316695906", "name": "Mitsunori Abe"}, {"authorId": "15879456", "name": "R. Abhaichand"}, {"authorId": "2243443625", "name": "W. Abhayaratna"}, {"authorId": "144317308", "name": "A. Abhyankar"}, {"authorId": "2316662314", "name": "I. Abidin"}, {"authorId": "2322386331", "name": "Hiba Abou Assi"}, {"authorId": "2184728405", "name": "Jose L Accini Mendoza"}, {"authorId": "2316662664", "name": "Mine Adas"}, {"authorId": "66962626", "name": "J. Agaiby"}, {"authorId": "2253639425", "name": "D. K. Agarwal"}, {"authorId": "2316660941", "name": "Maher Agha"}, {"authorId": "2316677290", "name": "Azazuddin Ahmed"}, {"authorId": "5549191", "name": "P. Ahtiainen"}, {"authorId": "3729474", "name": "E. Aigner"}, {"authorId": "2316660425", "name": "Naik Ajay"}, {"authorId": "2316674991", "name": "Norsiah Ali"}, {"authorId": "1441403748", "name": "Amer Al-Karadsheh"}, {"authorId": "2316659766", "name": "Roy Allison"}, {"authorId": "2316659271", "name": "Dale C. Allison"}, {"authorId": "2316661769", "name": "Diana Alpenidze"}, {"authorId": "46891464", "name": "Y. Altuntas"}, {"authorId": "1404732770", "name": "A. Al-Zoebi"}, {"authorId": "1694055115", "name": "Roy Ambuj"}, {"authorId": "2313658910", "name": "J. Amerena"}, {"authorId": "2316803735", "name": "R. J. Anderson"}, {"authorId": "2316663269", "name": "Toshiaki Ando"}, {"authorId": "2295530723", "name": "Robert Andrews"}, {"authorId": "2316660916", "name": "E. Antonova"}, {"authorId": "38287823", "name": "K. Appel"}, {"authorId": "4679375", "name": "F. B. Arantes"}, {"authorId": "5714671", "name": "M. Araz"}, {"authorId": "8905618", "name": "Y. Arbel"}, {"authorId": "2378176275", "name": "José L. Arenas León"}, {"authorId": "7781827", "name": "Georgia Argyrakopoulou"}, {"authorId": "66999599", "name": "M. Ariani"}, {"authorId": "2300751196", "name": "M. A. Arias Mendoza"}, {"authorId": "2253397008", "name": "Ahmed A. Arif"}, {"authorId": "16056700", "name": "J. Arneja"}, {"authorId": "6767192", "name": "V. Aroda"}, {"authorId": "2239290931", "name": "Louis J. Aronne"}, {"authorId": "2250590872", "name": "Margaret Arstall"}, {"authorId": "2316662467", "name": "N?jaimeh Asamoah"}, {"authorId": "47847324", "name": "M. Ašanin"}, {"authorId": "2220529764", "name": "Hanid Audish"}, {"authorId": "2316670367", "name": "Rodica Avram"}, {"authorId": "2111436686", "name": "A. Badat"}, {"authorId": "3971886", "name": "C. Badiu"}, {"authorId": "2111594196", "name": "Wa'el Bakdash"}, {"authorId": "5545363", "name": "O. Bakıner"}, {"authorId": "2316661781", "name": "Vuyokazi N. Bandezi"}, {"authorId": "10708874", "name": "L. H. Bang"}, {"authorId": "2301122443", "name": "Sandeep Bansal"}, {"authorId": "2316660972", "name": "Marietta Baranyai"}, {"authorId": "2295381305", "name": "Olga Barbarash"}, {"authorId": "2242800821", "name": "M. Barber"}, {"authorId": "107897419", "name": "Otis Barnum"}, {"authorId": "2401007043", "name": "G. Barone Rochette"}, {"authorId": "2316659094", "name": "A. Bashkin"}, {"authorId": "2331195578", "name": "Seth J. Baum"}, {"authorId": "2297607562", "name": "Harold E. Bays"}, {"authorId": "1737255085", "name": "A. Bazzoni Ruiz"}, {"authorId": "2316662527", "name": "Maciej Beckowski"}, {"authorId": "2316661074", "name": "Y. Beerachee"}, {"authorId": "2266668413", "name": "S. Bellary"}, {"authorId": "2316661764", "name": "L. Belousova"}, {"authorId": "2226373073", "name": "M. Berk"}, {"authorId": "2316661985", "name": "Marc A. P. Bernstein"}, {"authorId": "39631696", "name": "C. Berra"}, {"authorId": "2316670375", "name": "Isaac Beshay"}, {"authorId": "2311648299", "name": "Ajit Bhagwat"}, {"authorId": "9951118", "name": "A. Bhan"}, {"authorId": "2316661686", "name": "William C. Biggs"}, {"authorId": "2292859271", "name": "Liana Billings"}, {"authorId": "2083419446", "name": "F. Bitar"}, {"authorId": "2316660141", "name": "Bradley Block"}, {"authorId": "2316662658", "name": "Simona Bo"}, {"authorId": "2302482119", "name": "Paweł Bogdański"}, {"authorId": "52319503", "name": "O. Bolshakova"}, {"authorId": "2338642139", "name": "Alla A. Boshchenko"}, {"authorId": "120420135", "name": "H. Bosworth"}, {"authorId": "1404732088", "name": "R. Botero Lopez"}, {"authorId": "2311647656", "name": "Morten Bøttcher"}, {"authorId": "2111550040", "name": "R. Bourgeois"}, {"authorId": "91464099", "name": "D. Brautigam"}, {"authorId": "2316659137", "name": "Cristian F. Breton"}, {"authorId": "2257562491", "name": "A. Broadley"}, {"authorId": "2111377649", "name": "A. Brockmyre"}, {"authorId": "2316658957", "name": "Steven K. Brodie"}, {"authorId": "2316671151", "name": "M. Bucci"}, {"authorId": "3860090", "name": "H. Budinčević"}, {"authorId": "2239010666", "name": "M. Budoff"}, {"authorId": "2316659218", "name": "Barry Buffman"}, {"authorId": "3503872", "name": "N. Buljubasíc"}, {"authorId": "12129938", "name": "Supawan Buranapin"}, {"authorId": "2274398578", "name": "L. Burgess"}, {"authorId": "2275041956", "name": "B. Burguera"}, {"authorId": "2316659049", "name": "Olena Buriakovska"}, {"authorId": "2306020784", "name": "Silvio Buscemi"}, {"authorId": "2297054852", "name": "Robert Busch"}, {"authorId": "2242415528", "name": "John B. Buse"}, {"authorId": "14131369", "name": "R. Buynak"}, {"authorId": "2239666028", "name": "Maria Byrne"}, {"authorId": "13163243", "name": "Elena Caceaune"}, {"authorId": "2187998425", "name": "A. J. Cadena Bonfanti"}, {"authorId": "2240224304", "name": "Cornell Calinescu"}, {"authorId": "2316659065", "name": "Robert S. Call"}, {"authorId": "7287010", "name": "Silvija Canecki Varžić"}, {"authorId": "2253408136", "name": "K. Cannon"}, {"authorId": "2313845703", "name": "Matt Capehorn"}, {"authorId": "2260682738", "name": "Bertrand Cariou"}, {"authorId": "2316661492", "name": "Jeffrey Carr"}, {"authorId": "2316660858", "name": "Rodolfo Carrillo-Jimenez"}, {"authorId": "2316660735", "name": "Marcelo Casas"}, {"authorId": "2289914311", "name": "Almudena Castro"}, {"authorId": "2316661427", "name": "Ahmet Çelik"}, {"authorId": "2301192319", "name": "Cintia Cercato"}, {"authorId": "2097077826", "name": "Ondřej Čermák"}, {"authorId": "4723127", "name": "J. Cha"}, {"authorId": "2316659961", "name": "Carolina Chacón"}, {"authorId": "1423270568", "name": "Tira Chaicha-Brom"}, {"authorId": "2298109126", "name": "Sandeep Chandra"}, {"authorId": "11918489", "name": "M. Chettibi"}, {"authorId": "15954746", "name": "Julia Chevts"}, {"authorId": "2289255232", "name": "J. Christopher"}, {"authorId": "2142902510", "name": "W. Chrustowski"}, {"authorId": "2316661740", "name": "Adriana Cif"}, {"authorId": "2317229635", "name": "Rebecca Clark"}, {"authorId": "2316660836", "name": "W. Clark"}, {"authorId": "2253713358", "name": "Piers Clifford"}, {"authorId": "151071668", "name": "K. Coetzee"}, {"authorId": "2316659053", "name": "Giulia Cogni"}, {"authorId": "2275664820", "name": "Anna Maria Colao"}, {"authorId": "2249285553", "name": "David M. Colquhoun"}, {"authorId": "2283321610", "name": "Mauricio Concha"}, {"authorId": "2316661642", "name": "J. Condit"}, {"authorId": "2316658870", "name": "Christian Constance"}, {"authorId": "2316654141", "name": "C. Constantin"}, {"authorId": "2316644521", "name": "S. Constantinescu"}, {"authorId": "2311649861", "name": "Clive Corbett"}, {"authorId": "2111567777", "name": "George M. Cornett"}, {"authorId": "2316661696", "name": "Marcelo Correia"}, {"authorId": "2316742881", "name": "Fiorenzo Cortinovis"}, {"authorId": "2316660599", "name": "Dana Cosma"}, {"authorId": "2316661017", "name": "Steven Creely"}, {"authorId": "2316675874", "name": "David Cross"}, {"authorId": "2316661736", "name": "Brian Curtis"}, {"authorId": "2316659244", "name": "Wojciech Czochra"}, {"authorId": "2185245090", "name": "N. Daboul"}, {"authorId": "2316660873", "name": "Selçuk Dagdelen"}, {"authorId": "2316662964", "name": "Ronald D'agostino"}, {"authorId": "2316662783", "name": "Cuong Dang"}, {"authorId": "2316748524", "name": "Sudip Datta"}, {"authorId": "2316661007", "name": "A. K. Davuluri"}, {"authorId": "134707978", "name": "S. Dawood"}, {"authorId": "2378175612", "name": "Douwe de Jong"}, {"authorId": "2401008235", "name": "Carmen De La Cuesta"}, {"authorId": "65882548", "name": "M. O. de los Ríos Ibarra"}, {"authorId": "2401008594", "name": "C. de Pablo"}, {"authorId": "2401009426", "name": "Michel De Pauw"}, {"authorId": "2401008671", "name": "Alexander Dela Llana"}, {"authorId": "2316661027", "name": "Maja Delibasic"}, {"authorId": "1405159775", "name": "D. Delić-Brkljačić"}, {"authorId": "2316659234", "name": "Thibaud Demicheli"}, {"authorId": "2316661021", "name": "Ralf J. Denger"}, {"authorId": "2316661078", "name": "Devang Desai"}, {"authorId": "120964130", "name": "Piyush Desai"}, {"authorId": "2250793255", "name": "Cyrus V Desouza"}, {"authorId": "2305586853", "name": "Dror Dicker"}, {"authorId": "12192825", "name": "N. Djenić"}, {"authorId": "2316660143", "name": "Simon Dobson"}, {"authorId": "2352095972", "name": "Masayuki Doi"}, {"authorId": "2316659949", "name": "Jesse Doran"}, {"authorId": "2220115997", "name": "Reinhart Dorman"}, {"authorId": "2316662342", "name": "F. Dotta"}, {"authorId": "2316660794", "name": "C. E. Dukes"}, {"authorId": "2311652235", "name": "E. Duronto"}, {"authorId": "145077787", "name": "R. Durst"}, {"authorId": "35664945", "name": "I. Dvoryashina"}, {"authorId": "2311653256", "name": "Iftikhar O Ebrahim"}, {"authorId": "2316660048", "name": "Holger Eggebrecht"}, {"authorId": "2248371849", "name": "Kenneth Egstrup"}, {"authorId": "2316662566", "name": "E. I. Ekinci"}, {"authorId": "2316658925", "name": "Björn Eliasson"}, {"authorId": "2316660745", "name": "Ken Eliasson"}, {"authorId": "47917737", "name": "G. Enache"}, {"authorId": "2316659201", "name": "Dan Enculescu"}, {"authorId": "2316658955", "name": "Patrick English"}, {"authorId": "2316659795", "name": "P. Ermakova"}, {"authorId": "2316658879", "name": "O. Ershova"}, {"authorId": "49772318", "name": "Hirotaka Ezaki"}, {"authorId": "2307420089", "name": "M. Ezhov"}, {"authorId": "2316658906", "name": "Eduardo Farias"}, {"authorId": "2316653175", "name": "Javier M. Farias"}, {"authorId": "2316659955", "name": "P. S. Farsky"}, {"authorId": "2316814605", "name": "Daniel Ferreira"}, {"authorId": "40911465", "name": "Pierre Filteau"}, {"authorId": "2111436132", "name": "M. P. Finneran"}, {"authorId": "2316661163", "name": "Eric M. Folkens"}, {"authorId": "2393517928", "name": "Alberto G. T. Fonseca"}, {"authorId": "2316661226", "name": "L. Fonseca"}, {"authorId": "2316659026", "name": "Steven Fordan"}, {"authorId": "2235700126", "name": "Nyda Fourie"}, {"authorId": "2316659220", "name": "Sara França"}, {"authorId": "2274348325", "name": "Denise R. Franco"}, {"authorId": "2268048209", "name": "Edward Franek"}, {"authorId": "2311653667", "name": "Keith Friedman"}, {"authorId": "4355829", "name": "L. Frittitta"}, {"authorId": "2316659287", "name": "M. Froer"}, {"authorId": "7487963", "name": "K. Fučkar"}, {"authorId": "2311654478", "name": "Kenshi Fujii"}, {"authorId": "2316659125", "name": "Ryoko Fujita"}, {"authorId": "2316660431", "name": "Yasushi Fukushima"}, {"authorId": "2316660757", "name": "Mohamed Fulat"}, {"authorId": "2311648068", "name": "Mahesh C Fulwani"}, {"authorId": "2307907054", "name": "Grzegorz Gajos"}, {"authorId": "2316659769", "name": "A. Galyavich"}, {"authorId": "7849411", "name": "M. Gambill"}, {"authorId": "66413829", "name": "Dheeraj K. Gandotra"}, {"authorId": "2316670373", "name": "Gandy Winston"}, {"authorId": "2401008839", "name": "P. A. Garcia Hernandez"}, {"authorId": "2401009600", "name": "Raymundo García Reza"}, {"authorId": "2305126829", "name": "Naveen Garg"}, {"authorId": "2347510481", "name": "S. Garg"}, {"authorId": "2309037004", "name": "W. T. Garvey"}, {"authorId": "2316661292", "name": "Juan C. Garza"}, {"authorId": "1401390188", "name": "B. Gatta-Cherifi"}, {"authorId": "47618440", "name": "V. Gelev"}, {"authorId": "2111436275", "name": "Steven A. Geller"}, {"authorId": "2253411657", "name": "Jeffrey G. Geohas"}, {"authorId": "2316662845", "name": "Borislav Georgiev"}, {"authorId": "2280321318", "name": "Adline Ghazi"}, {"authorId": "2242346484", "name": "Matthew P Gilbert"}, {"authorId": "2316662938", "name": "Olga Gilinskaya"}, {"authorId": "2314082451", "name": "G. Gislason"}, {"authorId": "2354298475", "name": "Dilek Gogas Yavuz"}, {"authorId": "2349784832", "name": "O. González Albarrán"}, {"authorId": "2284460518", "name": "I. Gordeev"}, {"authorId": "2316659773", "name": "Sidney C. Gorton"}, {"authorId": "2401010364", "name": "Tone Gretland Valderhaug"}, {"authorId": "2281315126", "name": "B. Groenemeijer"}, {"authorId": "2044226", "name": "Ibrahim Gul"}, {"authorId": "2275413523", "name": "Lars Gullestad"}, {"authorId": "36589021", "name": "I. Gurieva"}, {"authorId": "2316659969", "name": "Galina N. Guseva"}, {"authorId": "4747183", "name": "A. Hagenow"}, {"authorId": "2316026213", "name": "M. Haluzík"}, {"authorId": "2261454229", "name": "S. Halvorsen"}, {"authorId": "2316662574", "name": "Naima Hammoudi"}, {"authorId": "35518152", "name": "K. Hanaoka"}, {"authorId": "2097202105", "name": "Nicolae Hancu"}, {"authorId": "2219710448", "name": "U. Hanusch"}, {"authorId": "2316660999", "name": "Kathleen Harris"}, {"authorId": "2311654850", "name": "Barry E. Harris"}, {"authorId": "14681055", "name": "M. Hartleib"}, {"authorId": "2316660890", "name": "Aaron Hartman"}, {"authorId": "2070291592", "name": "Y. Hata"}, {"authorId": "2316660685", "name": "Brian Heimer"}, {"authorId": "36906338", "name": "Lee Herman"}, {"authorId": "2311648759", "name": "William Herzog"}, {"authorId": "2316659775", "name": "Eric Hewitt"}, {"authorId": "11362805", "name": "Peter Heymer"}, {"authorId": "38973194", "name": "Shirish Hiremath"}, {"authorId": "2316661009", "name": "Joeran Hjelmesaeth"}, {"authorId": "2316661816", "name": "R. G. Høgalmen"}, {"authorId": "1419564019", "name": "H. O. Høivik"}, {"authorId": "2274398338", "name": "Helene Holmer"}, {"authorId": "2316671149", "name": "Olha Horoshko"}, {"authorId": "2316660762", "name": "Patricia M. Houser"}, {"authorId": "2311646422", "name": "Jens D Hove"}, {"authorId": "2311648711", "name": "I-Chang Hsieh"}, {"authorId": "50197490", "name": "J. Hulot"}, {"authorId": "2316670253", "name": "Zanariah Hussein"}, {"authorId": "2305247407", "name": "T. Ilashchuk"}, {"authorId": "6199291", "name": "E. Ilveskoski"}, {"authorId": "2316670377", "name": "Irina Ipatko"}, {"authorId": "2313385556", "name": "A. Iranmanesh"}, {"authorId": "34744125", "name": "T. Isawa"}, {"authorId": "2316659936", "name": "Moises Issa"}, {"authorId": "2239007447", "name": "B. Iteld"}, {"authorId": "2275348701", "name": "Takamasa Iwasawa"}, {"authorId": "2316660743", "name": "Danish Jabbar"}, {"authorId": "2316748853", "name": "Richard A. Jackson"}, {"authorId": "2111567569", "name": "Ewart Jackson-Voyzey"}, {"authorId": "2292229917", "name": "Stephan Jacob"}, {"authorId": "6725847", "name": "N. Jaffrani"}, {"authorId": "2316659193", "name": "M. Jardula"}, {"authorId": "4331161", "name": "Ania M Jastreboff"}, {"authorId": "2242512340", "name": "S. E. Jensen"}, {"authorId": "3814304", "name": "T. Jerkins"}, {"authorId": "2316660588", "name": "Silvia A. Jiménez‐Ramos"}, {"authorId": "2401008017", "name": "Sawhney Jitendra Pal Singh"}, {"authorId": "2316662774", "name": "W. Johnson"}, {"authorId": "2316659953", "name": "J. M. Joyce"}, {"authorId": "2101904227", "name": "Małgorzata Józefowska"}, {"authorId": "2316659465", "name": "Prakash Jugnundan"}, {"authorId": "15732102", "name": "W. Jungmair"}, {"authorId": "1737089344", "name": "J. Jurowiecki"}, {"authorId": "5268096", "name": "T. Kadokami"}, {"authorId": "6560930", "name": "D. Kahali"}, {"authorId": "2316662599", "name": "G. Kahrmann"}, {"authorId": "2297703967", "name": "S. Kaiser"}, {"authorId": "2316661845", "name": "Piotr Kalmucki"}, {"authorId": "2316660979", "name": "Mehmet Kanadasi"}, {"authorId": "9930887", "name": "D. Kandath"}, {"authorId": "2316659425", "name": "Grzegorz Kania"}, {"authorId": "117641462", "name": "J. Kannan"}, {"authorId": "2316659423", "name": "Cornelia Kapp"}, {"authorId": "49494683", "name": "A. Karczmarczyk"}, {"authorId": "2311653001", "name": "Athanasios Kartalis"}, {"authorId": "2316660702", "name": "Susanne Kaser"}, {"authorId": "2311647295", "name": "S. Kasim"}, {"authorId": "2316658863", "name": "Richard Kastelic"}, {"authorId": "2316689829", "name": "Toshiaki Kato"}, {"authorId": "4269293", "name": "T. Katova"}, {"authorId": "2261429988", "name": "Upendra Kaul"}, {"authorId": "2251938211", "name": "A. Kautzky-Willer"}, {"authorId": "2316661048", "name": "M. Kawanishi"}, {"authorId": "2250766794", "name": "M. Kayikcioglu"}, {"authorId": "2316659899", "name": "Elena E. Kazakova"}, {"authorId": "2316659538", "name": "Philip Keeling"}, {"authorId": "121841081", "name": "H. Kempe"}, {"authorId": "5918729", "name": "D. Kereiakes"}, {"authorId": "5848843", "name": "M. Kerneis"}, {"authorId": "2316661802", "name": "Tiina Keski-Opas"}, {"authorId": "3580558", "name": "S. Khadra"}, {"authorId": "2294960652", "name": "L. Khaisheva"}, {"authorId": "2316659207", "name": "Marina Kharakhulakh"}, {"authorId": "13083316", "name": "T. Khlevchuk"}, {"authorId": "2316659085", "name": "Jeffrey Khoo"}, {"authorId": "4011101", "name": "S. Kiatchoosakun"}, {"authorId": "2316661269", "name": "Noriyuki Kinoshita"}, {"authorId": "2316649698", "name": "Masaharu Kinoshita"}, {"authorId": "2316661837", "name": "Ryoji Kitamura"}, {"authorId": "4156869", "name": "A. Kiyosue"}, {"authorId": "2316661215", "name": "Irina Klavina"}, {"authorId": "2316661205", "name": "Eric Klein"}, {"authorId": "51253765", "name": "Zdeněk Klimsa"}, {"authorId": "1381460619", "name": "David Klonoff"}, {"authorId": "2316659921", "name": "Eric Klug"}, {"authorId": "47406936", "name": "Z. Kobalava"}, {"authorId": "2316659859", "name": "Satoshi Kodera"}, {"authorId": "46389000", "name": "T. Koga"}, {"authorId": "2248287071", "name": "A. Kokkinos"}, {"authorId": "2097668447", "name": "P. Kolečkář"}, {"authorId": "2316659986", "name": "László Könyves"}, {"authorId": "2244347332", "name": "Michael J Koren"}, {"authorId": "24420471", "name": "A. Kormann"}, {"authorId": "2249801525", "name": "K. Kostner"}, {"authorId": "2111463813", "name": "Kristin Kreutzmann"}, {"authorId": "66748912", "name": "S. Krishinan"}, {"authorId": "48603985", "name": "Sathya Krishnasamy"}, {"authorId": "2316660820", "name": "Inga Krivosheeva"}, {"authorId": "4316297", "name": "I. Kruljac"}, {"authorId": "2316661170", "name": "Ted Kubicki"}, {"authorId": "8338285", "name": "L. Kuchař"}, {"authorId": "2316661212", "name": "Monika Kujawiak"}, {"authorId": "2316659895", "name": "Hideyuki Kunishige"}, {"authorId": "2316659811", "name": "Melinda Kurtinecz"}, {"authorId": "2401006923", "name": "Hugo R. Kurtz Lisboa"}, {"authorId": "103771333", "name": "M. Kushnir"}, {"authorId": "2316663471", "name": "Yulian Kyyak"}, {"authorId": "2316660592", "name": "Arija Lace"}, {"authorId": "2243172864", "name": "T. Lakka"}, {"authorId": "3542388", "name": "N. Lalic"}, {"authorId": "2267958976", "name": "Katarina Lalić"}, {"authorId": "52025318", "name": "V. Lambadiari"}, {"authorId": "9906573", "name": "Leonidas Lanaras"}, {"authorId": "2314394441", "name": "Chim C. Lang"}, {"authorId": "2240642363", "name": "Marie-France Langlois"}, {"authorId": "2316659106", "name": "Joseph Lash"}, {"authorId": "6418456", "name": "G. Latkovskis"}, {"authorId": "2316660315", "name": "David Lau"}, {"authorId": "2117452105", "name": "J. R. Lazcano Soto"}, {"authorId": "2282115300", "name": "C. L. Le Roux"}, {"authorId": "2316659186", "name": "Gilbert N. Ledesma"}, {"authorId": "2274387440", "name": "L. Y. Lee"}, {"authorId": "115477481", "name": "Thung-Lip Lee"}, {"authorId": "2316779424", "name": "Kelvin Lee"}, {"authorId": "2276284832", "name": "M. Lehrke"}, {"authorId": "2316660886", "name": "Silmara O. Leite"}, {"authorId": "2316659429", "name": "Agata Leksycka"}, {"authorId": "50389016", "name": "Thomas Lenzmeier"}, {"authorId": "2240087894", "name": "Frida Leonetti"}, {"authorId": "2316659399", "name": "Viktoriia Leonidova"}, {"authorId": "2243616355", "name": "Norman Lepor"}, {"authorId": "2316660415", "name": "Melissa Leung"}, {"authorId": "2316659131", "name": "O. Levchenko"}, {"authorId": "91078966", "name": "P. Levins"}, {"authorId": "2316660540", "name": "Louis J. Levy"}, {"authorId": "2316726242", "name": "Matthew L. Lewis"}, {"authorId": "2267975516", "name": "E. Liberopoulos"}, {"authorId": "4678810", "name": "I. Liberty"}, {"authorId": "98384825", "name": "C. Lindholm"}, {"authorId": "2241459485", "name": "A. Linhart"}, {"authorId": "2311682091", "name": "Ming-En Liu"}, {"authorId": "2316667037", "name": "Jenny Liu"}, {"authorId": "2273578037", "name": "Holly Lofton"}, {"authorId": "2316659713", "name": "T. Logemann"}, {"authorId": "2306402761", "name": "Johan J Lombaard"}, {"authorId": "39857647", "name": "L. Lombard"}, {"authorId": "84547162", "name": "R. Lorraine"}, {"authorId": "2316663466", "name": "Charles F. Lovell"}, {"authorId": "2295446905", "name": "B. Ludvik"}, {"authorId": "2316670229", "name": "Monika Lukaszewicz"}, {"authorId": "4286741", "name": "G. Lupkovics"}, {"authorId": "49811661", "name": "S. Lupovitch"}, {"authorId": "2316659848", "name": "Sirona Lupu"}, {"authorId": "2316661328", "name": "Mary Lynch"}, {"authorId": "2269398076", "name": "Zoreslava Lysak"}, {"authorId": "2316660788", "name": "T. A. Lysenko"}, {"authorId": "2316647922", "name": "Hajime Maeda"}, {"authorId": "2316659431", "name": "Itaru Maeda"}, {"authorId": "5784176", "name": "Michael Mæng"}, {"authorId": "2227987287", "name": "Ajaykumar Mahajan"}, {"authorId": "2271068874", "name": "V. Maher"}, {"authorId": "2302138272", "name": "L. N. Maia"}, {"authorId": "2111545800", "name": "Ellen Makotoko"}, {"authorId": "2316670672", "name": "A. Malavazos"}, {"authorId": "2316661199", "name": "Jan Malecha"}, {"authorId": "2022367337", "name": "E. Malicherova"}, {"authorId": "8147197", "name": "M. Manita"}, {"authorId": "5249634", "name": "E. Mannucci"}, {"authorId": "2248023735", "name": "Viacheslav Mareev"}, {"authorId": "2316661565", "name": "L. Marin"}, {"authorId": "2316670540", "name": "Tatiana N. Markova"}, {"authorId": "5986998", "name": "S. Marso"}, {"authorId": "2316660909", "name": "F.M.A.C. Martens"}, {"authorId": "2316700301", "name": "Cuper Martinez"}, {"authorId": "2401009905", "name": "Carlos A. Martinez Cano"}, {"authorId": "2316686708", "name": "C. Martins"}, {"authorId": "2401007529", "name": "Luis Masmiquel Comas"}, {"authorId": "2334847184", "name": "Takashi Matsumoto"}, {"authorId": "2316655151", "name": "Kenneth Mcdonald"}, {"authorId": "2307000888", "name": "Barbara Mcgowan"}, {"authorId": "2241443330", "name": "F. Mcgrew"}, {"authorId": "2061539358", "name": "Barry K. Mclean"}, {"authorId": "2316660842", "name": "David D. Mcpherson"}, {"authorId": "113841325", "name": "J. F. Merino Torres"}, {"authorId": "2316661285", "name": "P. Meyers"}, {"authorId": "2306329785", "name": "S. Meyhöfer"}, {"authorId": "2401008384", "name": "Pedro Mezquita Raya"}, {"authorId": "145501926", "name": "M. Milanova"}, {"authorId": "2265633458", "name": "D. Miličić"}, {"authorId": "2316709323", "name": "G. Miller"}, {"authorId": "2316661738", "name": "Richard E. Mills"}, {"authorId": "89528632", "name": "N. Mîndrescu"}, {"authorId": "2238031542", "name": "G. Mingrone"}, {"authorId": "2316659015", "name": "Dotska A. Minkova"}, {"authorId": "48532135", "name": "M. Mirani"}, {"authorId": "2316661123", "name": "Alexander Miras"}, {"authorId": "1403553388", "name": "Cristina Mistodie"}, {"authorId": "15030575", "name": "S. Mitomo"}, {"authorId": "2257804670", "name": "Sanjay Mittal"}, {"authorId": "20465837", "name": "T. Miyake"}, {"authorId": "2316660099", "name": "Naomasa Miyamoto"}, {"authorId": "2224076725", "name": "David E. Molony"}, {"authorId": "2311648155", "name": "Pedro Monteiro"}, {"authorId": "6606947", "name": "T. Mooe"}, {"authorId": "2218103705", "name": "Naeem Moosa"}, {"authorId": "2027219187", "name": "C. Morales Portillo"}, {"authorId": "2389205297", "name": "Enrique C. Morales Villegas"}, {"authorId": "119430019", "name": "Emily J. Morawski"}, {"authorId": "8425824", "name": "C. Morbey"}, {"authorId": "2316661350", "name": "Robert P. Morin"}, {"authorId": "39574080", "name": "K. Morisaki"}, {"authorId": "84468675", "name": "M. Morosanu"}, {"authorId": "2051855284", "name": "O. Mosenzon"}, {"authorId": "2253384226", "name": "Yuriy Mostovoy"}, {"authorId": "49605084", "name": "I. Munir"}, {"authorId": "2300611600", "name": "Fabrizio Muratori"}, {"authorId": "2316662494", "name": "Ryan Murray"}, {"authorId": "2316660192", "name": "A. Murthy"}, {"authorId": "2316661196", "name": "M. Myint"}, {"authorId": "2316661137", "name": "Galyna Myshanych"}, {"authorId": "2111474929", "name": "Valerica Nafornita"}, {"authorId": "2316659994", "name": "Takuya Nagano"}, {"authorId": "2316663126", "name": "Sunil Nair"}, {"authorId": "8317553", "name": "S. Nakhle"}, {"authorId": "12537935", "name": "M. Natsuaki"}, {"authorId": "2175313075", "name": "Bindu M Nayak"}], "url": "https://www.semanticscholar.org/paper/76c15dc9402b36c123890225ce16e681ec7ee146", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "1866d4b57a0b5670c60bcb0f708d51f14e371dfb", "title": "Global, regional, and national burden of chronic kidney disease in adults, 1990-2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023.", "abstract": "BACKGROUND\nChronic kidney disease (CKD) is common and ranks among the leading causes of mortality and morbidity. This analysis aimed to present global CKD estimates using the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 to inform evidence-based policies for CKD identification and treatment.\n\n\nMETHODS\nThis analysis focused on adults aged 20 years and older over the period 1990 to 2023, from 204 countries and territories. Data sources used were published literature, vital registration systems, kidney failure treatment registries, and household surveys. Estimates of CKD burden, including deaths, incidence, prevalence, and disability-adjusted life-years (DALYs), were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool. A comparative risk assessment approach estimated the proportion of cardiovascular deaths attributable to impaired kidney function and estimated risk factors for CKD.\n\n\nFINDINGS\nGlobally, in 2023, 788 million (95% uncertainty interval 743-843) people aged 20 years and older were estimated to have CKD, up from 378 million (354-407) in 1990. The global age-standardised prevalence of CKD in adults was 14·2% (13·4-15·2), a relative rise of 3·5% (2·7-4·1) from 1990. The region with the highest age-standardised prevalence was north Africa and the Middle East (18·0%; 16·9-19·4). Most people had stage 1-3 CKD, with a combined prevalence of 13·9% (13·1-15·0). In 2023, CKD was the ninth leading cause of death globally, accounting for 1·48 million (1·30-1·65) deaths, and the 12th leading cause of DALYs, with an age-standardised DALY rate of 769·2 (691·8-857·4) per 100 000. Impaired kidney function as a risk factor accounted for 11·5% (8·4-14·5) of cardiovascular deaths. High fasting plasma glucose, body-mass index, and systolic blood pressure were all leading risk factors for CKD DALYs.\n\n\nINTERPRETATION\nCKD is a major global health issue, with rising prevalence and increasing importance as a cause of death and as a risk factor for cardiovascular death. A better understating of aetiology, appropriate screening, and implementation programmes are needed to translate advances in CKD treatment into improved patient outcomes.\n\n\nFUNDING\nGates Foundation, Wellcome, US National Kidney Foundation, and US National Institute of Diabetes and Digestive and Kidney Diseases.", "year": 2025, "publicationDate": "2025-11-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "The Lancet", "journal": {"name": "Lancet"}, "citationCount": 214, "referenceCount": 47, "influentialCitationCount": 26, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/s0140-6736(25)01853-7", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2365180677", "name": "Patrick B Mark"}, {"authorId": "2182557573", "name": "Lauryn K. Stafford"}, {"authorId": "38043924", "name": "Morgan E. Grams"}, {"authorId": "2368364551", "name": "Hasan Aalruz"}, {"authorId": "8006287", "name": "S. A. Abd ElHafeez"}, {"authorId": "2214547919", "name": "Ahmed A. Abdelgalil"}, {"authorId": "3877692", "name": "R. Abdulkader"}, {"authorId": "25879283", "name": "H. Abeywickrama"}, {"authorId": "38309555", "name": "O. Abiodun"}, {"authorId": "2350544597", "name": "Dmitry Abramov"}, {"authorId": "2391399952", "name": "M. Abrar"}, {"authorId": "2205025502", "name": "Lucas Guimarães Abreu"}, {"authorId": "2292286479", "name": "Bilyaminu Abubakar"}, {"authorId": "2255548316", "name": "Salahdein Aburuz"}, {"authorId": "2336125290", "name": "I. Y. Addo"}, {"authorId": "1648641102", "name": "O. Adegboye"}, {"authorId": "2337440317", "name": "N. A. Adegoke"}, {"authorId": "2036896134", "name": "T. AdeyeOluwa"}, {"authorId": "87594019", "name": "Q. Adnani"}, {"authorId": "19240512", "name": "B. Ahinkorah"}, {"authorId": "2051829450", "name": "Sajjad Ahmad"}, {"authorId": "2385622138", "name": "K. Ahmad"}, {"authorId": "2238603971", "name": "Ali Ahmadi"}, {"authorId": "82708878", "name": "A. M. Ahmadzade"}, {"authorId": "2202059613", "name": "Ayman Ahmed"}, {"authorId": "18152864", "name": "A. Ahmed"}, {"authorId": "2382853157", "name": "Nesredin Ahmed"}, {"authorId": "2391957830", "name": "Shahzaib Ahmed"}, {"authorId": "2217281065", "name": "Syed Anees Ahmed"}, {"authorId": "4809369", "name": "Marjan Ajami"}, {"authorId": "2372285041", "name": "Mohammadreza Akbari"}, {"authorId": "2051752762", "name": "Oluwasefunmi Akeju"}, {"authorId": "2321662560", "name": "M. Akkaif"}, {"authorId": "2320578167", "name": "Salah Al Awaidy"}, {"authorId": "29878612", "name": "Hanadi Al Hamad"}, {"authorId": "40018788", "name": "S. A. Al Hasan"}, {"authorId": "15636120", "name": "Yazan Al Thaher"}, {"authorId": "2341728513", "name": "Z. Al-Aly"}, {"authorId": "1441043246", "name": "Fahmi Y. Al-Ashwal"}, {"authorId": "2210896515", "name": "Mohammed ALBashtawy"}, {"authorId": "14984657", "name": "Shereen M. Aleidi"}, {"authorId": "2146189165", "name": "A. Alfalki"}, {"authorId": "5453886", "name": "F. Alhalaiqa"}, {"authorId": "2385617254", "name": "Khalid A. Alhasan"}, {"authorId": "2291144865", "name": "Endale Alemayehu Ali"}, {"authorId": "2290909725", "name": "Rafat Ali"}, {"authorId": "2290859018", "name": "Syed Shujait Shujait Ali"}, {"authorId": "2385889661", "name": "Syed Yusuf Ali"}, {"authorId": "1400876373", "name": "Samah W. Al-Jabi"}, {"authorId": "6302098", "name": "Mohammed Z Allouh"}, {"authorId": "2344605216", "name": "W. Almagharbeh"}, {"authorId": "2290678599", "name": "O. Almidani"}, {"authorId": "2097552290", "name": "K. Alnawafleh"}, {"authorId": "2008046440", "name": "Najim Z. Alshahrani"}, {"authorId": "2290675825", "name": "Awais Altaf"}, {"authorId": "1382885100", "name": "N. Alvis-Guzmán"}, {"authorId": "1403602554", "name": "Y. Al-Worafi"}, {"authorId": "145285996", "name": "K. Alzoubi"}, {"authorId": "5018881", "name": "A. S. Al-zubairi"}, {"authorId": "2382688577", "name": "Masoud Aman mohammadi"}, {"authorId": "5864008", "name": "Hubert Amu"}, {"authorId": "2150587410", "name": "F. Anagnostakis"}, {"authorId": "2284464756", "name": "Abhishek Anil"}, {"authorId": "13251851", "name": "A. Anyasodor"}, {"authorId": "66216574", "name": "G. L. Apostol"}, {"authorId": "2391389798", "name": "Walter Appati"}, {"authorId": "2391389721", "name": "S. O. Araromi"}, {"authorId": "3386308", "name": "A. Aravkin"}, {"authorId": "2237749014", "name": "Johan Ärnlöv"}, {"authorId": "2307957936", "name": "Jesu Arockiaraj"}, {"authorId": "2274209431", "name": "B. Asiamah-Asare"}, {"authorId": "96741630", "name": "Y. Asri"}, {"authorId": "50985321", "name": "Ashagre Molla Assaye"}, {"authorId": "2290678654", "name": "M. Atout"}, {"authorId": "31957553", "name": "Khursheed Aurangzeb"}, {"authorId": "6548829", "name": "A. Awotidebe"}, {"authorId": "2272814893", "name": "S. Aziz"}, {"authorId": "2284963026", "name": "D. Azzolino"}, {"authorId": "2066279699", "name": "Muhammad Badar"}, {"authorId": "2268050697", "name": "Mohamad Amin Bakhshali"}, {"authorId": "5742561", "name": "S. Ballew"}, {"authorId": "7491657", "name": "Ovidiu Constantin Baltatu"}, {"authorId": "2284465594", "name": "Maciej Banach"}, {"authorId": "2278597125", "name": "Mainak Bardhan"}, {"authorId": "17730451", "name": "H. Barqawi"}, {"authorId": "2385618182", "name": "M. Bashar"}, {"authorId": "2346216001", "name": "Shahid Bashir"}, {"authorId": "2301475435", "name": "Mohammad-Mahdi Bastan"}, {"authorId": "2114710407", "name": "S. Basu"}, {"authorId": "4642370", "name": "Neeraj Bedi"}, {"authorId": "2323550267", "name": "Bekalu Mekonen Belay"}, {"authorId": "2165988550", "name": "Makda Abate Belew"}, {"authorId": "145905521", "name": "A. Bello"}, {"authorId": "2257771144", "name": "Luis Belo"}, {"authorId": "51219877", "name": "A. N. Bermudez"}, {"authorId": "5394111", "name": "A. Bhagavathula"}, {"authorId": "2238707441", "name": "Sonu M M Bhaskar"}, {"authorId": "48187469", "name": "A. Bhat"}, {"authorId": "2296901690", "name": "P. Bhattacharjee"}, {"authorId": "2884780", "name": "Jasvinder Singh Bhatti"}, {"authorId": "144543740", "name": "G. K. Bhatti"}, {"authorId": "6052092", "name": "S. Biadgilign"}, {"authorId": "2250916779", "name": "Yacong Bo"}, {"authorId": "4164087", "name": "Trupti Bodhare"}, {"authorId": "31701375", "name": "A. Boloor"}, {"authorId": "2294764509", "name": "Hamed Borhany"}, {"authorId": "2284922699", "name": "Michael Brauer"}, {"authorId": "2239782730", "name": "Raffaele Bugiardini"}, {"authorId": "2230553438", "name": "A. Busari"}, {"authorId": "2252556385", "name": "Yasser K. Bustanji"}, {"authorId": "2095668991", "name": "L. Cámera"}, {"authorId": "2290678913", "name": "L. A. Campos"}, {"authorId": "1390182889", "name": "Ismael Campos-Nonato"}, {"authorId": "2245815118", "name": "J. Carrero"}, {"authorId": "2075424659", "name": "M. Carvalho"}, {"authorId": "2258876114", "name": "A. Catapano"}, {"authorId": "2354898839", "name": "Monica Cattafesta"}, {"authorId": "67265933", "name": "Muthia Cenderadewi"}, {"authorId": "6688893", "name": "E. Cenko"}, {"authorId": "2363016258", "name": "Deepak Chandramohan"}, {"authorId": "3776828", "name": "Vijay Kumar Chattu"}, {"authorId": "2187429646", "name": "L. D. Chau"}, {"authorId": "2387444403", "name": "A. A. Chaudhary"}, {"authorId": "2330995382", "name": "An-Tian Chen"}, {"authorId": "2385645083", "name": "Haojin Cheng"}, {"authorId": "2338113243", "name": "N. Chew"}, {"authorId": "1752776846", "name": "Patrick R. Ching"}, {"authorId": "2348232574", "name": "Hou In Chou"}, {"authorId": "2273628271", "name": "Sonali Gajanan Choudhari"}, {"authorId": "2250539617", "name": "E. Chowdhury"}, {"authorId": "153249891", "name": "D. Chu"}, {"authorId": "4391310", "name": "S. Chung"}, {"authorId": "2056876010", "name": "A. Columbus"}, {"authorId": "2237996248", "name": "P. Cortesi"}, {"authorId": "46716901", "name": "K. Courville"}, {"authorId": "2038003550", "name": "N. Cruz-Martins"}, {"authorId": "2293932074", "name": "O. Dadras"}, {"authorId": "3624717", "name": "L. Dandona"}, {"authorId": "5666172", "name": "R. Dandona"}, {"authorId": "145713163", "name": "Anh Kim Dang"}, {"authorId": "2116118874", "name": "Saswati Das"}, {"authorId": "6060120", "name": "T. Dejenie"}, {"authorId": "2006619137", "name": "Vinoth Gnana Chellaiyan Devanbu"}, {"authorId": "4595776", "name": "Devananda Devegowda"}, {"authorId": "49161416", "name": "Syed Masudur Rahman Dewan"}, {"authorId": "4484167", "name": "M. Dhimal"}, {"authorId": "6458810", "name": "M. Dhimal"}, {"authorId": "2310023815", "name": "D. Díaz"}, {"authorId": "2381171932", "name": "H. Do"}, {"authorId": "2290664960", "name": "Thao Phuong Do"}, {"authorId": "150186187", "name": "L. Doan"}, {"authorId": "2301474533", "name": "Mario D’Oria"}, {"authorId": "2017439674", "name": "Robert Kokou Dowou"}, {"authorId": "2184861570", "name": "A. C. Dsouza"}, {"authorId": "2284822920", "name": "Bruce B Duncan"}, {"authorId": "2385584211", "name": "S. Dutta"}, {"authorId": "2391275287", "name": "Cynthia Edeh"}, {"authorId": "4122865", "name": "H. Edinur"}, {"authorId": "2290675758", "name": "Ferry Efendi"}, {"authorId": "6453700", "name": "Michael Ekholuenetale"}, {"authorId": "52118835", "name": "T. Ekundayo"}, {"authorId": "134097776", "name": "Iman El Sayed"}, {"authorId": "2275383299", "name": "Muhammed Elhadi"}, {"authorId": "1404083458", "name": "W. El‐Huneidi"}, {"authorId": "2382688779", "name": "Sherif Elkannishy"}, {"authorId": "47808779", "name": "Mohamed A. Elmonem"}, {"authorId": "20755719", "name": "M. Elnaem"}, {"authorId": "2336543125", "name": "Christopher Esezobor"}, {"authorId": "2223309037", "name": "Derese Eshetu"}, {"authorId": "1403501810", "name": "Juan Espinosa-Montero"}, {"authorId": "2315476406", "name": "A. Fagbamigbe"}, {"authorId": "2352718251", "name": "M. Farooqui"}, {"authorId": "2238866003", "name": "Alireza Feizkhah"}, {"authorId": "1381096686", "name": "G. Fekadu"}, {"authorId": "2261545784", "name": "N. Ferreira"}, {"authorId": "2238725777", "name": "Florian Fischer"}, {"authorId": "9543363", "name": "F. Fogacci"}, {"authorId": "2324044402", "name": "C. Fortuna Rodrigues"}, {"authorId": "2257476639", "name": "Marisa Freitas"}, {"authorId": "133595936", "name": "A. Fukunaga"}, {"authorId": "2016027149", "name": "A. Gad"}, {"authorId": "2144469", "name": "A. Gaidhane"}, {"authorId": "2339538536", "name": "Abduzhappar Gaipov"}, {"authorId": "38800431", "name": "Balasubramanian Ganesh"}, {"authorId": "2238648712", "name": "M. W. Gebregergis"}, {"authorId": "2332136236", "name": "K. Y. Gete"}, {"authorId": "1492058243", "name": "L. Gharaibeh"}, {"authorId": "2294766515", "name": "Mohammadreza Ghasemi"}, {"authorId": "2321658116", "name": "Zainab Gholami"}, {"authorId": "2301476736", "name": "Ehsan Gholami"}, {"authorId": "123735338", "name": "Alemea girmay"}, {"authorId": "2257792039", "name": "Amit Goel"}, {"authorId": "4479203", "name": "Mahaveer Golechha"}, {"authorId": "2368357564", "name": "Aman Goyal"}, {"authorId": "2321621445", "name": "Ashna Grover"}, {"authorId": "2238754234", "name": "Shi-Yang Guan"}, {"authorId": "2110341354", "name": "R. Gupta"}, {"authorId": "2110344784", "name": "R. Gupta"}, {"authorId": "2285625539", "name": "Anish Gupta"}, {"authorId": "2118972662", "name": "Sapna Gupta"}, {"authorId": "67059011", "name": "J. Guzmán-Esquivel"}, {"authorId": "2238634615", "name": "Najah R. Hadi"}, {"authorId": "2223104577", "name": "Arian Haghtalab"}, {"authorId": "2180892523", "name": "Hailey Hagins"}, {"authorId": "2757243", "name": "N. Hamdy"}, {"authorId": "2385564291", "name": "M. Hamza"}, {"authorId": "2292291783", "name": "Qiuxia Han"}, {"authorId": "120859783", "name": "H. Hasani"}, {"authorId": "2256975570", "name": "Mohammad Hashem Hashempur"}, {"authorId": "152756515", "name": "M. Hasnain"}, {"authorId": "2385614656", "name": "I. Hassan"}, {"authorId": "2253270656", "name": "S. Hay"}, {"authorId": "2028940230", "name": "Jiawei He"}, {"authorId": "1447007561", "name": "G. Heidari"}, {"authorId": "2301474367", "name": "Y. Hiraike"}, {"authorId": "2135606874", "name": "P. hoogar"}, {"authorId": "2348236757", "name": "Alamgir Hossain"}, {"authorId": "101437057", "name": "M. Hosseinzade"}, {"authorId": "4297895", "name": "M. Hostiuc"}, {"authorId": "2349221945", "name": "Mengsi Hu"}, {"authorId": "2182357478", "name": "H. Huynh"}, {"authorId": "1382272510", "name": "S. E. Ibitoye"}, {"authorId": "143885693", "name": "U. Ibrahim"}, {"authorId": "2238869369", "name": "Irena Ilic"}, {"authorId": "1380305981", "name": "M. Imam"}, {"authorId": "12187174", "name": "L. Irham"}, {"authorId": "47199510", "name": "M. A. Isa"}, {"authorId": "2373932537", "name": "D. Islam"}, {"authorId": "2290911595", "name": "M. Islam"}, {"authorId": "2349064467", "name": "Md Fakrul Islam"}, {"authorId": "9125121", "name": "N. Ismail"}, {"authorId": "2304596463", "name": "H. Iso"}, {"authorId": "35056603", "name": "G. Isola"}, {"authorId": "4140212", "name": "M. Iwagami"}, {"authorId": "2266558296", "name": "Vennila Jaganathan"}, {"authorId": "150016895", "name": "A. Jairoun"}, {"authorId": "2391390664", "name": "Navid Jamali"}, {"authorId": "2363793093", "name": "Jazlan Jamaluddin"}, {"authorId": "5753816", "name": "R. Janardhanan"}, {"authorId": "2031828993", "name": "S. Jayaram"}, {"authorId": "2333123323", "name": "Mohammed Jemal"}, {"authorId": "2368401795", "name": "Seogsong Jeong"}, {"authorId": "2075161726", "name": "Vivekanand Jha"}, {"authorId": "2391400311", "name": "Nathan Jibat"}, {"authorId": "1851144", "name": "J. Jonas"}, {"authorId": "2238736456", "name": "Nitin Joseph"}, {"authorId": "2391668328", "name": "A. Joseph"}, {"authorId": "2205339348", "name": "Charity Ehimwenma Joshua"}, {"authorId": "2190967779", "name": "Kripa Josten"}, {"authorId": "144494294", "name": "J. Jozwiak"}, {"authorId": "2149055178", "name": "Sang-Hyuk Jung"}, {"authorId": "2238866203", "name": "Z. Kabir"}, {"authorId": "2142196964", "name": "Alia Kabir"}, {"authorId": "2252002153", "name": "A. Kakkar"}, {"authorId": "2290676360", "name": "Sanjay Kalra"}, {"authorId": "2336132425", "name": "M. Kamal"}, {"authorId": "2257689450", "name": "Ashwin Kamath"}, {"authorId": "6501926", "name": "E. Kanmiki"}, {"authorId": "2301041196", "name": "K. Kanmodi"}, {"authorId": "2348236363", "name": "Debasish Kar"}, {"authorId": "151474399", "name": "Reema A. Karasneh"}, {"authorId": "1381813954", "name": "Samad Karkhah"}, {"authorId": "47469437", "name": "M. A. Kausar"}, {"authorId": "2236867123", "name": "Y. Kebede"}, {"authorId": "2391399383", "name": "Abenezer Zenebe Kebede"}, {"authorId": "2172234799", "name": "Yousef S. Khader"}, {"authorId": "28523733", "name": "H. Khajuria"}, {"authorId": "12210117", "name": "A. Khalil"}, {"authorId": "2368350253", "name": "A. A. Khan"}, {"authorId": "2292305902", "name": "Mohammad Jobair Khan"}, {"authorId": "2368400505", "name": "Sumaiya Khan"}, {"authorId": "2292301404", "name": "A. Khan"}, {"authorId": "2391815482", "name": "I. Khan"}, {"authorId": "1918363346", "name": "S. Khasbage"}, {"authorId": "2282940664", "name": "Z. Khashim"}, {"authorId": "6858939", "name": "M. Khatatbeh"}, {"authorId": "1380168609", "name": "F. F. Khidri"}, {"authorId": "2376789497", "name": "M. Khokhar"}, {"authorId": "2390274875", "name": "A. Kisa"}, {"authorId": "2250941780", "name": "Mika Kivimäki"}, {"authorId": "2385621446", "name": "A. Km"}, {"authorId": "5754021", "name": "N. Kobyliak"}, {"authorId": "2225872788", "name": "M. Kokkorakis"}, {"authorId": "4480853", "name": "F. Kompani"}, {"authorId": "89013013", "name": "Tapos Kormoker"}, {"authorId": "2301555498", "name": "O. Korzh"}, {"authorId": "2316917987", "name": "Karel Kostev"}, {"authorId": "16257031", "name": "S. L. Koulmane Laxminarayana"}, {"authorId": "2350007108", "name": "I. Kretchy"}, {"authorId": "46434163", "name": "K. Krishan"}, {"authorId": "2360196257", "name": "Yuvaraj Krishnamoorthy"}, {"authorId": "6953990", "name": "Barthelemy Kuate Defo"}, {"authorId": "48528674", "name": "M. Kuddus"}, {"authorId": "66664809", "name": "M. Kulimbet"}, {"authorId": "2368484357", "name": "Jogender Kumar"}, {"authorId": "2241655536", "name": "G. Kumar"}, {"authorId": "2386416295", "name": "T. Kumar"}, {"authorId": "2294783614", "name": "Rakesh Kumar"}, {"authorId": "4442939", "name": "S. Kunutsor"}, {"authorId": "2063078588", "name": "M. D. Kurniasari"}, {"authorId": "2092134956", "name": "Ambily Kuttikkattu"}, {"authorId": "6011710", "name": "J. P. Kuwornu"}, {"authorId": "2301477973", "name": "Ville Kytö"}, {"authorId": "6853586", "name": "C. Lahariya"}, {"authorId": "46351403", "name": "I. Landires"}, {"authorId": "2218878739", "name": "Duc Tin Le"}, {"authorId": "2368368210", "name": "Minh H. N. Le"}, {"authorId": "4163808", "name": "C. Ledda"}, {"authorId": "2339251978", "name": "Hwa-Young Lee"}, {"authorId": "2381889811", "name": "D. A. Lemma"}, {"authorId": "2272087652", "name": "A. Levey"}, {"authorId": "2386191957", "name": "Chengfeng Li"}, {"authorId": "2327508759", "name": "Jinbo Li"}, {"authorId": "2245813743", "name": "Lee-Ling Lim"}, {"authorId": "2151059224", "name": "Xuefeng Liu"}, {"authorId": "2385596058", "name": "Zhenyu Liu"}, {"authorId": "2108374969", "name": "Jinshi Liu"}, {"authorId": "2368386479", "name": "Zhe Liu"}, {"authorId": "2294935505", "name": "Erand Llanaj"}, {"authorId": "2276730458", "name": "G. Lucchetti"}, {"authorId": "2301477387", "name": "Jay B. Lusk"}, {"authorId": "6503503", "name": "A. Lutambi"}, {"authorId": "2301477069", "name": "Lei Lv"}, {"authorId": "40960131", "name": "R. Maalman"}, {"authorId": "2003277076", "name": "S. Mahalingam"}, {"authorId": "2348234756", "name": "Nozad Hussein Mahmood"}, {"authorId": "2238835584", "name": "Azeem Majeed"}, {"authorId": "37376396", "name": "O. Makram"}, {"authorId": "2385637706", "name": "Tabarak Malik"}, {"authorId": "2265773022", "name": "A. Malik"}, {"authorId": "2250375140", "name": "A. A. Mamun"}, {"authorId": "2259151718", "name": "R. Martinez-Piedra"}, {"authorId": "2257522259", "name": "Winfried März"}, {"authorId": "2282133600", "name": "Sammer Marzouk"}, {"authorId": "2368364743", "name": "S. Masi"}, {"authorId": "2133227919", "name": "Soroush Masrouri"}, {"authorId": "2238191636", "name": "M. Mazidi"}, {"authorId": "2239774384", "name": "S. M. McPhail"}, {"authorId": "2185638351", "name": "Jitendra Meena"}, {"authorId": "2301474174", "name": "Asim Mehmood"}, {"authorId": "7423751", "name": "S. Mehrabi"}, {"authorId": "1380024449", "name": "H. Meles"}, {"authorId": "4460387", "name": "T. Meštrović"}, {"authorId": "14102951", "name": "C. Mettananda"}, {"authorId": "4688191", "name": "T. Miazgowski"}, {"authorId": "1405541357", "name": "K. Mihretie"}, {"authorId": "2104259944", "name": "Muhammad Agus Naufal Mikrajab"}, {"authorId": "35782788", "name": "Andreea Mirica"}, {"authorId": "48606797", "name": "E. Mirrakhimov"}, {"authorId": "2296920814", "name": "Vinaytosh Mishra"}, {"authorId": "2391508276", "name": "Amaresh Mishra"}, {"authorId": "5666060", "name": "P. Mithra"}, {"authorId": "7518496", "name": "N. Mohamed"}, {"authorId": "2368368130", "name": "Abdolreza Mohammadi"}, {"authorId": "2235340220", "name": "S. Mohammed"}, {"authorId": "2235220257", "name": "A. Mokdad"}, {"authorId": "2257549332", "name": "Stefania Mondello"}, {"authorId": "49853749", "name": "M. Moni"}, {"authorId": "4729444", "name": "N. Morovatdar"}, {"authorId": "2385617428", "name": "Amin Mousavi Khaneghah"}, {"authorId": "13170583", "name": "M. A. Mousnad"}, {"authorId": "88861006", "name": "Godfrey Mudhune"}, {"authorId": "2230284340", "name": "Efrén Murillo-Zamora"}, {"authorId": "2274256521", "name": "Christopher J. L. Murray"}, {"authorId": "1657306907", "name": "M. T. Mustapha"}, {"authorId": "1825640850", "name": "S. Nabipoorashrafi"}, {"authorId": "6663390", "name": "S. Nagaraju"}, {"authorId": "2348232061", "name": "Hiten Naik"}, {"authorId": "81105857", "name": "T. Nair"}, {"authorId": "2180964325", "name": "Shumaila Nargus"}, {"authorId": "2301479224", "name": "Abdallah Y Naser"}, {"authorId": "2320579527", "name": "M. Naser"}, {"authorId": "2348233084", "name": "Mahmoud Nassar"}, {"authorId": "2257558903", "name": "Gopalakrishnan Natarajan"}, {"authorId": "10146859", "name": "Z. Natto"}, {"authorId": "37939950", "name": "J. Nauman"}, {"authorId": "2368360671", "name": "Shalini Ganesh Nayak"}, {"authorId": "2234592224", "name": "Bruce Neal"}, {"authorId": "4067459", "name": "R. Negoi"}, {"authorId": "2210944355", "name": "O. Nekouei"}, {"authorId": "2220690675", "name": "H. Nguyen"}, {"authorId": "2348330958", "name": "Trang Nguyen"}, {"authorId": "2390610784", "name": "N. Nguyen"}, {"authorId": "2385594653", "name": "T. Nguyen"}, {"authorId": "2391315454", "name": "H. T. Nguyen"}, {"authorId": "2386077546", "name": "Huong Lan Thi Nguyen"}, {"authorId": "2249762655", "name": "T. Nguyen"}, {"authorId": "51896804", "name": "R. Niazi"}, {"authorId": "2288198856", "name": "L. Nieddu"}, {"authorId": "2292288750", "name": "Shuhei Nomura"}, {"authorId": "6367314", "name": "M. Noreen"}, {"authorId": "2238025859", "name": "J. J. Noubiap"}, {"authorId": "102248777", "name": "F. Nugen"}, {"authorId": "2238069591", "name": "Chijindu N Nwakama"}, {"authorId": "51980866", "name": "F. Nyande"}, {"authorId": "2254078686", "name": "C. I. Nzoputam"}, {"authorId": "2764609", "name": "B. Oancea"}, {"authorId": "2220355624", "name": "Osaretin Christabel Okonji"}, {"authorId": "2214992269", "name": "P. G. Okwute"}, {"authorId": "5965356", "name": "A. Olagunju"}, {"authorId": "153698763", "name": "T. Olanrewaju"}, {"authorId": "2311805673", "name": "A. Olawuyi"}, {"authorId": "2080133674", "name": "A. Olorukooba"}, {"authorId": "2054879272", "name": "Alberto Ortiz"}, {"authorId": "2348239271", "name": "A. Osman"}, {"authorId": "29002107", "name": "J. Ostrominski"}, {"authorId": "11679645", "name": "Elham H. Othman"}, {"authorId": "144259199", "name": "M. Owolabi"}, {"authorId": "7914257", "name": "I. Oyeyemi"}, {"authorId": "1434981825", "name": "Alicia Padrón-Monedero"}, {"authorId": "3353606", "name": "J. Padubidri"}, {"authorId": "3045706", "name": "A. Pană"}, {"authorId": "2382693583", "name": "Ke Pang"}, {"authorId": "65729311", "name": "Anca Mihaela Pantea Stoian"}, {"authorId": "2368366863", "name": "Ilias Papadimopoulos"}, {"authorId": "5258427", "name": "S. Pardhan"}, {"authorId": "2290679861", "name": "Romil R. Parikh"}, {"authorId": "121248348", "name": "Maja Pasovic"}, {"authorId": "2290679525", "name": "D. Patoulias"}, {"authorId": "51040919", "name": "Prince Peprah"}, {"authorId": "152198853", "name": "N. Perico"}, {"authorId": "2238869023", "name": "Simone Perna"}, {"authorId": "3996446", "name": "K. Polkinghorne"}, {"authorId": "2275463552", "name": "Djordje S. Popovic"}, {"authorId": "4072783", "name": "T. Porntaveetus"}, {"authorId": "4622282", "name": "Akila Prashant"}, {"authorId": "2274273478", "name": "J. Puvvula"}, {"authorId": "2368826701", "name": "Xiang Qi"}, {"authorId": "2080485758", "name": "B. Rachmat"}, {"authorId": "2233622478", "name": "Quinn Rafferty"}, {"authorId": "2238888965", "name": "Muhammad Aziz Rahman"}, {"authorId": "2110138427", "name": "Mosiur Rahman"}, {"authorId": "2240324745", "name": "M. Rahmati"}, {"authorId": "2281854133", "name": "Sunil Kumar Raina"}, {"authorId": "2212269645", "name": "Adarsh Raja"}, {"authorId": "145966304", "name": "P. Rajput"}, {"authorId": "2301475183", "name": "M. Ramadan"}, {"authorId": "83388304", "name": "Sheena Ramazanu"}, {"authorId": "2284151431", "name": "R. K. Rana"}, {"authorId": "2391654058", "name": "Asad Gul Rao"}, {"authorId": "2051687604", "name": "Ashkan Rasouli-Saravani"}, {"authorId": "6938681", "name": "D. Rathish"}, {"authorId": "113382461", "name": "S. K. Rauniyar"}, {"authorId": "2572338", "name": "S. Rawaf"}, {"authorId": "3810067", "name": "Lal B Rawal"}, {"authorId": "2290911651", "name": "M. M. Reddy"}, {"authorId": "2361015866", "name": "E. Redwan"}, {"authorId": "2241644157", "name": "G. Remuzzi"}, {"authorId": "13773828", "name": "N. Rezaei"}, {"authorId": "67298856", "name": "Leonardo Roever"}, {"authorId": "2278572993", "name": "Peter Rohloff"}, {"authorId": "114276654", "name": "Debby Syahru Romadlon"}, {"authorId": "2321381305", "name": "A. G. Ross"}, {"authorId": "2384721832", "name": "Hanieh Rouzbahani"}, {"authorId": "2060088310", "name": "Al Saad"}, {"authorId": "2269775", "name": "B. Saddik"}, {"authorId": "2279174683", "name": "U. Saeed"}, {"authorId": "2368383497", "name": "Mohd Saeed"}, {"authorId": "2290681333", "name": "M. Saeedi"}, {"authorId": "1435266654", "name": "Fatemeh Saheb Sharif‐Askari"}, {"authorId": "2131047983", "name": "A. Sahebkar"}, {"authorId": "2147341892", "name": "A. Salami"}, {"authorId": "2238768674", "name": "Mohamed Saleh"}, {"authorId": "2089481345", "name": "Y. Samodra"}, {"authorId": "32038062", "name": "V. P. Samuel"}, {"authorId": "2161665740", "name": "I. Santos"}, {"authorId": "2219381432", "name": "Aswini Saravanan"}, {"authorId": "2382686402", "name": "Saman Sargazi"}, {"authorId": "2335433943", "name": "Michele Sassano"}, {"authorId": "2433982968", "name": "B. Sathian"}, {"authorId": "6668845", "name": "M. Sawhney"}, {"authorId": "153491039", "name": "M. Schmidt"}, {"authorId": "2151589824", "name": "Art Schuermans"}, {"authorId": "7845551", "name": "H. Seifmanesh"}, {"authorId": "2086752950", "name": "S. Selvaraj"}, {"authorId": "2141388270", "name": "Yashendra Sethi"}, {"authorId": "2051578900", "name": "Allen Seylani"}, {"authorId": "81391579", "name": "M. Shahwan"}, {"authorId": "2199430", "name": "M. Shaikh"}, {"authorId": "79606897", "name": "Sunder Sham"}, {"authorId": "2193587729", "name": "M. A. Shamim"}, {"authorId": "2386565527", "name": "Xian Shao"}, {"authorId": "2324044277", "name": "A. Sharifan"}, {"authorId": "2368451513", "name": "Bunty Sharma"}, {"authorId": "2321654311", "name": "Sourabh Sharma"}, {"authorId": "145713771", "name": "S. Shastry"}, {"authorId": "2395373853", "name": "Wenming Shi"}, {"authorId": "2216881319", "name": "Md. Monir Hossain Shimul"}, {"authorId": "2275449230", "name": "A. Shittu"}, {"authorId": "2313188381", "name": "Abdul-karim Olayinka Shitu"}, {"authorId": "2238186845", "name": "Sunil Shrestha"}, {"authorId": "2123931886", "name": "Aman Shrestha"}, {"authorId": "5753738", "name": "P. Simkhada"}, {"authorId": "2153703275", "name": "Jasvinder A. Singh"}, {"authorId": "2302290831", "name": "Harmanjit Singh"}, {"authorId": "2245934071", "name": "N. Singh"}, {"authorId": "2185411687", "name": "Surjit Singh"}, {"authorId": "2185817858", "name": "Suha Soni"}, {"authorId": "2296835884", "name": "Aayushi Sood"}, {"authorId": "2142759910", "name": "Soroush Soraneh"}], "url": "https://www.semanticscholar.org/paper/1866d4b57a0b5670c60bcb0f708d51f14e371dfb", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "edf0ea011f58b4679d7e3fe9b57ccfb690d76c73", "title": "Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study", "abstract": "Summary Background Worldwide treatment recommendations for lowering blood pressure continue to be guided predominantly by blood pressure thresholds, despite strong evidence that the benefits of blood pressure reduction are observed in patients across the blood pressure spectrum. In this study, we aimed to investigate the implications of alternative strategies for offering blood pressure treatment, using the UK as an illustrative example. Methods We did a retrospective cohort study in primary care patients aged 30–79 years without cardiovascular disease, using data from the UK's Clinical Practice Research Datalink linked to Hospital Episode Statistics and Office for National Statistics mortality. We assessed and compared four different strategies to determine eligibility for treatment: using 2011 UK National Institute for Health and Care Excellence (NICE) guideline, or proposed 2019 NICE guideline, or blood pressure alone (threshold ≥140/90 mm Hg), or predicted 10-year cardiovascular risk alone (QRISK2 score ≥10%). Patients were followed up until the earliest occurrence of a cardiovascular disease diagnosis, death, or end of follow-up period (March 31, 2016). For each strategy, we estimated the proportion of patients eligible for treatment and number of cardiovascular events that could be prevented with treatment. We then estimated eligibility and number of events that would occur during 10 years in the UK general population. Findings Between Jan 1, 2011, and March 31, 2016, 1 222 670 patients in the cohort were followed up for a median of 4·3 years (IQR 2·5–5·2). 271 963 (22·2%) patients were eligible for treatment under the 2011 NICE guideline, 327 429 (26·8%) under the proposed 2019 NICE guideline, 481 859 (39·4%) on the basis of a blood pressure threshold of 140/90 mm Hg or higher, and 357 840 (29·3%) on the basis of a QRISK2 threshold of 10% or higher. During follow-up, 32 183 patients were diagnosed with cardiovascular disease (overall rate 7·1 per 1000 person-years, 95% CI 7·0–7·2). Cardiovascular event rates in patients eligible for each strategy were 15·2 per 1000 person-years (95% CI 15·0–15·5) under the 2011 NICE guideline, 14·9 (14·7–15·1) under the proposed 2019 NICE guideline, 11·4 (11·3–11·6) with blood pressure threshold alone, and 16·9 (16·7–17·1) with QRISK2 threshold alone. Scaled to the UK population, we estimated that 233 152 events would be avoided under the 2011 NICE guideline (28 patients needed to treat for 10 years to avoid one event), 270 233 under the 2019 NICE guideline (29 patients), 301 523 using a blood pressure threshold (38 patients), and 322 921 using QRISK2 threshold (27 patients). Interpretation A cardiovascular risk-based strategy (QRISK2 ≥10%) could prevent over a third more cardiovascular disease events than the 2011 NICE guideline and a fifth more than the 2019 NICE guideline, with similar efficiency regarding number treated per event avoided. Funding National Institute for Health Research.", "year": 2019, "publicationDate": "2019-08-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet (London, England)", "pages": "663 - 671", "volume": "394"}, "citationCount": 36, "referenceCount": 46, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.thelancet.com/article/S0140673619313595/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "3486771", "name": "E. Herrett"}, {"authorId": "46927298", "name": "S. Gadd"}, {"authorId": "97861796", "name": "R. Jackson"}, {"authorId": "49687191", "name": "K. Bhaskaran"}, {"authorId": "152486433", "name": "Elizabeth Williamson"}, {"authorId": "7568209", "name": "T. V. van Staa"}, {"authorId": "6410497", "name": "R. Sofat"}, {"authorId": "118509023", "name": "A. Timmis"}, {"authorId": "3487798", "name": "L. Smeeth"}], "url": "https://www.semanticscholar.org/paper/edf0ea011f58b4679d7e3fe9b57ccfb690d76c73", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "ef71a94b7e6328a13351c392d5b42f3847f5f360", "title": "Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study.", "abstract": "BACKGROUND\nDietary guidelines recommend minimising consumption of whole-fat dairy products, as they are a source of saturated fats and presumed to adversely affect blood lipids and increase cardiovascular disease and mortality. Evidence for this contention is sparse and few data for the effects of dairy consumption on health are available from low-income and middle-income countries. Therefore, we aimed to assess the associations between total dairy and specific types of dairy products with mortality and major cardiovascular disease.\n\n\nMETHODS\nThe Prospective Urban Rural Epidemiology (PURE) study is a large multinational cohort study of individuals aged 35-70 years enrolled from 21 countries in five continents. Dietary intakes of dairy products for 136 384 individuals were recorded using country-specific validated food frequency questionnaires. Dairy products comprised milk, yoghurt, and cheese. We further grouped these foods into whole-fat and low-fat dairy. The primary outcome was the composite of mortality or major cardiovascular events (defined as death from cardiovascular causes, non-fatal myocardial infarction, stroke, or heart failure). Hazard ratios (HRs) were calculated using multivariable Cox frailty models with random intercepts to account for clustering of participants by centre.\n\n\nFINDINGS\nBetween Jan 1, 2003, and July 14, 2018, we recorded 10 567 composite events (deaths [n=6796] or major cardiovascular events [n=5855]) during the 9·1 years of follow-up. Higher intake of total dairy (>2 servings per day compared with no intake) was associated with a lower risk of the composite outcome (HR 0·84, 95% CI 0·75-0·94; ptrend=0·0004), total mortality (0·83, 0·72-0·96; ptrend=0·0052), non-cardiovascular mortality (0·86, 0·72-1·02; ptrend=0·046), cardiovascular mortality (0·77, 0·58-1·01; ptrend=0·029), major cardiovascular disease (0·78, 0·67-0·90; ptrend=0·0001), and stroke (0·66, 0·53-0·82; ptrend=0·0003). No significant association with myocardial infarction was observed (HR 0·89, 95% CI 0·71-1·11; ptrend=0·163). Higher intake (>1 serving vs no intake) of milk (HR 0·90, 95% CI 0·82-0·99; ptrend=0·0529) and yogurt (0·86, 0·75-0·99; ptrend=0·0051) was associated with lower risk of the composite outcome, whereas cheese intake was not significantly associated with the composite outcome (0·88, 0·76-1·02; ptrend=0·1399). Butter intake was low and was not significantly associated with clinical outcomes (HR 1·09, 95% CI 0·90-1·33; ptrend=0·4113).\n\n\nINTERPRETATION\nDairy consumption was associated with lower risk of mortality and major cardiovascular disease events in a diverse multinational cohort.\n\n\nFUNDING\nFull funding sources are listed at the end of the paper (see Acknowledgments).", "year": 2018, "publicationDate": "2018-11-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet", "journal": {"name": "Lancet", "pages": "\n          2288-2297\n        ", "volume": "392 10161"}, "citationCount": 348, "referenceCount": 31, "influentialCitationCount": 12, "isOpenAccess": true, "openAccessPdfUrl": "https://ecommons.aku.edu/pakistan_fhs_mc_chs_chs/682", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Agricultural and Food Sciences", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145319397", "name": "M. Dehghan"}, {"authorId": "5852860", "name": "A. Mente"}, {"authorId": "39289861", "name": "S. Rangarajan"}, {"authorId": "46795405", "name": "P. Sheridan"}, {"authorId": "2075337902", "name": "V. Mohan"}, {"authorId": "2990577", "name": "R. Iqbal"}, {"authorId": "2110340686", "name": "Rajeev Gupta"}, {"authorId": "4389179", "name": "S. Lear"}, {"authorId": "1380326663", "name": "E. Wentzel-Viljoen"}, {"authorId": "2135483634", "name": "Á. Avezum"}, {"authorId": "1380327422", "name": "P. López-Jaramillo"}, {"authorId": "9000040", "name": "P. Mony"}, {"authorId": "31936743", "name": "R. Varma"}, {"authorId": "47654488", "name": "Rajesh Kumar"}, {"authorId": "6901809", "name": "J. Chifamba"}, {"authorId": "3658822", "name": "K. Alhabib"}, {"authorId": "4906293", "name": "N. Mohammadifard"}, {"authorId": "4629628", "name": "A. Oguz"}, {"authorId": "144226747", "name": "F. Lanas"}, {"authorId": "6382221", "name": "D. Różańska"}, {"authorId": "10034785", "name": "K. Bostrom"}, {"authorId": "1977461", "name": "K. Yusoff"}, {"authorId": "1705441118", "name": "Lungiswa P Tsolkile"}, {"authorId": "7015123", "name": "A. Dans"}, {"authorId": "37021165", "name": "A. Yusufali"}, {"authorId": "3632985", "name": "A. Orlandini"}, {"authorId": "49255119", "name": "P. Poirier"}, {"authorId": "3950678", "name": "R. Khatib"}, {"authorId": "1830393563", "name": "B. Hu"}, {"authorId": "2113553874", "name": "Li Wei"}, {"authorId": "144704400", "name": "Lu Yin"}, {"authorId": "1705440796", "name": "Ai Deeraili"}, {"authorId": "3947311", "name": "K. Yeates"}, {"authorId": "47572577", "name": "R. Yusuf"}, {"authorId": "35291134", "name": "Noorhassim Ismail"}, {"authorId": "6096905", "name": "D. Mozaffarian"}, {"authorId": "145005538", "name": "K. Teo"}, {"authorId": "145276610", "name": "Sonia S Anand"}, {"authorId": "144636283", "name": "S. Yusuf"}], "url": "https://www.semanticscholar.org/paper/ef71a94b7e6328a13351c392d5b42f3847f5f360", "_run_id": "xjMrzIAwbP5kw3s1b", "_dataset_id": "90oBOBbBHjwjDPkv8"}
{"paperId": "c416d04a59ef8961356d5e4909c54c112ecab916", "title": "A comprehensive review on direct air carbon capture (DAC) technology by adsorption: From fundamentals to applications", "abstract": null, "year": 2024, "publicationDate": "2024-12-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Energy Conversion and Management", "journal": {"name": "Energy Conversion and Management"}, "citationCount": 54, "referenceCount": 215, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2230448314", "name": "Huijin Xu"}, {"authorId": "2369622925", "name": "Liyang Yu"}, {"authorId": "50561132", "name": "Cheng Chong"}, {"authorId": "2324781708", "name": "Fuqiang Wang"}], "url": "https://www.semanticscholar.org/paper/c416d04a59ef8961356d5e4909c54c112ecab916", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "09cb3c72b0c57a07ac47233438a29ecd3b4af682", "title": "Atmospheric alchemy: The energy and cost dynamics of direct air carbon capture", "abstract": "Amid a relentless global climate crisis, the 28th Conference of the Parties (COP28) spotlighted Direct Air Carbon Capture (DACC) as a key intervention to mitigate escalating temperatures and CO2 levels. The Intergovernmental Panel on Climate Change (IPCC) underscores the urgency of this challenge, stipulating the need for robust CO2 removal strategies. It sets a daunting yet crucial target: capture 85 million metric tons of CO2 by 2030, escalating to 980 million metric tons by 2050, to achieve net-zero emissions (IEA, Executive Summary—Direct Air Capture 2022—Analysis. https://www.iea.org/reports/direct-air-capture-2022/executive-summary). Despite this imperative, the existing 19 operational DAC facilities globally face significant barriers, including prohibitive costs and stringent regulations, which impede their large-scale application (Ozkan et al.). Current status and pillars of direct air capture technologies. Iscience (2022). While COP28 stopped short of delineating a definitive roadmap for DAC, this article addresses a vital aspect of this technology: DAC processes’ substantial energy and heat requirements, which are integral to their operational efficiency and economic viability. This article illuminates pathways for future technological evolution and cost optimization through an in-depth analysis of these requirements, thereby charting a course toward a more effective and scalable DAC infrastructure. With atmospheric CO2 exceeding 420 ppm, the clock is ticking on the climate crisis. DAC offers a revolutionary approach to directly remove this excess CO2, acting as a critical tool in our fight for a sustainable future. However, current DAC systems face the challenge of high energy consumption. Continuous fan operation for air intake and sorbent material regeneration, consuming nearly 2000–3000 kWh per ton of CO2 captured, are major contributors. Optimizing these processes is crucial. Advancements in sorbent efficiency, system design that minimizes parasitic energy losses, and seamless integration with renewable energy sources are key to slashing DAC’s energy demands. By reducing its carbon footprint and enhancing economic viability, these advancements can unlock the full potential of DAC to become a game-changer in combating climate change and securing a cleaner future for our planet. Given the significant energy and heat requirements of DACC processes, what technological innovations are necessary to make these systems more energy efficient and economically viable? Considering the substantial energy demands of DACC processes, what are the most promising avenues for reducing these requirements to enhance the technology's scalability and cost-effectiveness? How can current technological limitations be overcome to scale up DACC effectively? What role could renewable energy sources play in meeting the energy and heat demands of DACC facilities, and how might this integration impact the overall carbon footprint of the carbon capture process? How do the energy and heat requirements of DACC technologies influence their location and infrastructure needs, particularly in relation to energy sources and heat sinks? What technological innovations or advancements are currently being explored to optimize the energy and heat efficiency of DACC processes, and what challenges do they face in terms of implementation and scaling? Given the significant role of DACC in achieving net-zero emissions targets, how can policy and regulatory frameworks be designed to support the development and deployment of energy-efficient DACC solutions?", "year": 2024, "publicationDate": "2024-07-09", "publicationTypes": ["JournalArticle"], "venue": "MRS Energy & Sustainability", "journal": {"name": "MRS Energy & Sustainability", "pages": "46 - 61", "volume": "12"}, "citationCount": 64, "referenceCount": 55, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1557/s43581-024-00091-5.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2254521261", "name": "Mihrimah Ozkan"}], "url": "https://www.semanticscholar.org/paper/09cb3c72b0c57a07ac47233438a29ecd3b4af682", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "88b5b970500ffc384721c7e17173570a56834389", "title": "Enhanced Direct Air Carbon Capture on NaX Zeolite by Electric‐Field Enhanced Physical Adsorption and In Situ CO2 Synergistic Effects of Cold Plasma", "abstract": "Direct air carbon capture (DAC) is vital to achieving negative CO2 emissions, with physical adsorption offering a cost‐effective and energy‐efficient solution. an advanced zeolite modification technique is presented using cold plasma, which enhances the CO2 adsorption efficiency of NaX zeolite by 11.5% after just 60 min. This method utilizes the electric field to reorganize cation distribution and pore structure and significantly improve the adsorption capacity, efficiency, and selectivity. Compared to traditional methods, this technique is simpler and more effective, as demonstrated through first‐principles calculations, thermodynamics, kinetics, and adsorption equilibrium studies.", "year": 2024, "publicationDate": "2024-08-07", "publicationTypes": ["JournalArticle"], "venue": "Advanced Functional Materials", "journal": {"name": "Advanced Functional Materials", "volume": "34"}, "citationCount": 24, "referenceCount": 42, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adfm.202408922", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2260471679", "name": "Minghai Shen"}, {"authorId": "2151079721", "name": "Fulin Kong"}, {"authorId": "2258544787", "name": "Wei Guo"}, {"authorId": "2268170850", "name": "Zhongqi Zuo"}, {"authorId": "2209443190", "name": "Chan Guo"}, {"authorId": "2416898", "name": "Lige Tong"}, {"authorId": "48759241", "name": "Shaowu Yin"}, {"authorId": "2268060853", "name": "Li Wang"}, {"authorId": "93506263", "name": "S. Kawi"}, {"authorId": "2238730040", "name": "Paul. K. Chu"}, {"authorId": "2152151373", "name": "Yulong Ding"}], "url": "https://www.semanticscholar.org/paper/88b5b970500ffc384721c7e17173570a56834389", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "55d9b569c161fcf9b7ac8ae34be011fa469f02df", "title": "Direct air capture (DAC): molten carbonate direct transformation of airborne CO2 to durable, useful carbon nanotubes and nano-onions", "abstract": "The concept and first demonstration of an effective direct air capture molten carbonate chemistry is presented.", "year": 2025, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "RSC Sustainability", "journal": {"name": "RSC Sustainability"}, "citationCount": 12, "referenceCount": 22, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1039/d4su00679h", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "102660149", "name": "G. Licht"}, {"authorId": "2311434834", "name": "Ethan Peltier"}, {"authorId": "2311435284", "name": "Simon Gee"}, {"authorId": "2274565732", "name": "Stuart Licht"}], "url": "https://www.semanticscholar.org/paper/55d9b569c161fcf9b7ac8ae34be011fa469f02df", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "493ba2f52b0c9f972592230aeb1a54c37eeaabb6", "title": "Prospective environmental burdens and benefits of fast-swing direct air carbon capture and storage", "abstract": "Direct air capture (DAC) in combination with storage of CO2 can lower atmospheric CO2 concentrations. This study investigates the environmental impact of a new fast-swing solid sorbent DAC system, including CO2 transport and storage, over its life cycle, using prospective life cycle assessment. This DAC technology is currently on technology readiness level 5 and is expected to operate on an industrial scale by 2030. The technology was upscaled to the industrial scale and future changes in the background over the lifetime of the system were included, such as electricity grid mix decarbonization. Environmental trade-offs for the new DAC system were assessed by comparing environmental benefits from CO2 sequestration with environmental burdens from production, operation and decommissioning. We considered three electricity generation configurations: grid-connected, wind-connected, and a hybrid configuration. We found net environmental benefits for all configurations and background scenarios for ecosystem damage and climate change. Net human health benefits were observed when the electricity grid decarbonizes quickly and without the use of a battery. The environmental benefits increase with decreasing electricity footprint and are comparable with other DAC technologies. This illustrates that the new DAC system can help to meet the climate goals.", "year": 2024, "publicationDate": "2024-07-17", "publicationTypes": ["JournalArticle"], "venue": "Scientific Reports", "journal": {"name": "Scientific Reports", "volume": "14"}, "citationCount": 17, "referenceCount": 46, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1038/s41598-024-66990-2", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1742213725", "name": "Anne B Ottenbros"}, {"authorId": "51034933", "name": "R. van Zelm"}, {"authorId": "34243307", "name": "Jasper Simons"}, {"authorId": "2106732907", "name": "Mitchell K. van der Hulst"}, {"authorId": "2155209496", "name": "Kiane de Kleijne"}, {"authorId": "2311837580", "name": "Hans de Neve"}, {"authorId": "4335045", "name": "M. Huijbregts"}], "url": "https://www.semanticscholar.org/paper/493ba2f52b0c9f972592230aeb1a54c37eeaabb6", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "eb0f4102473d5adfff5380f500933d0ab2013731", "title": "Exploration of a novel electrochemical CN coupling process: Urea synthesis from direct air carbon capture with nitrate wastewater.", "abstract": "Direct air capture (DAC) can be used to decrease the CO2 concentration in the atmosphere, but this requires substantial energy consumption. If residual waste carbon (in the form of bicarbonate solution) from DAC can be directly reused, it might present a novel method for overcoming the aforementioned challenges. Electrochemical CN coupling methods for synthesizing urea have garnered considerable attention for waste carbon utilization, but the carbon source is high-purity CO2. No research has been conducted regarding the application of bicarbonate solution as the carbon source. This study proposes a proof-of-concept electrochemical CN coupling process for synthesizing urea using bicarbonate solution from DAC as the carbon source and nitrate from wastewater as the nitrogen source. These results confirmed the feasibility of synthesizing urea using a three-electrode system employing TF and CuInS2/TF as the working electrodes via potentiostatic electrolysis. Under the optimal conditions (initial pH 5.0 and applied potential of -1.3 V vs. Ag/AgCl), the urea yield after 2 h of electrolysis reached 3017.2 μg h-1 mgcat.-1 and an average Faradaic efficiency of 19.6 %. The in-situ attenuated total reflection surface-enhanced infrared absorption spectroscopy indicated a gradual increase in the intensity of the -CONH bond signal on the surface of the CuInS2/TF electrode as the reaction progressed. This implied that this bond may be a key chemical group in this process. The density functional theory calculations demonstrated that *CONH was a pivotal intermediate during CN coupling, and a two-step CN coupling reaction path was proposed. *NH + *CO primarily transformed into *CONH, followed by the conversion reaction of *CONH + *NO to *NOCONH2. This study offers a groundbreaking approach for waste carbon utilization from DAC and holds the potential to furnish technical underpinnings for advancing electrochemical CN coupling methods.", "year": 2023, "publicationDate": "2023-12-01", "publicationTypes": ["JournalArticle"], "venue": "Science of the Total Environment", "journal": {"name": "The Science of the total environment", "pages": "\n          169722\n        "}, "citationCount": 13, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.scitotenv.2023.169722", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2277432256", "name": "Ying Chen"}, {"authorId": "2272494687", "name": "Yuan Liu"}, {"authorId": "2277450547", "name": "Shujie Hu"}, {"authorId": "2277417891", "name": "Di Wu"}, {"authorId": "2277585970", "name": "Mengyue Zhang"}, {"authorId": "4380637", "name": "Zhiliang Cheng"}], "url": "https://www.semanticscholar.org/paper/eb0f4102473d5adfff5380f500933d0ab2013731", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "835b020246c9ee0541a682ebd72cd924626e27c8", "title": "Thermodynamic loss analysis of a liquid-sorbent direct air carbon capture plant", "abstract": "Direct air capture of CO 2 is often presented as a promising technology to help mitigate climate change, although proposed processes are highly energy intensive. We analyze Carbon Engineering’s 1 Mt-CO 2 /year natural-gas-powered direct air capture (DAC) process, which requires 273.2 MW per plant, where we find that 252 MW are irreversibly lost, corresponding to a second-law efficiency of 7.8%. Our component-level analysis details the mechanisms by which these losses of thermodynamic work potential occur in the most energy-intensive plant segments. Here, we emphasize the effects of chemical exergy dissipation in the air contactor, where stored chemical exergy is released as low-grade heat into the environment. Other major losses occur in the calciner and its preheat cyclones due to the high temperature demanded by its internal chemical reaction, as well as in the water knockout system, CO 2 compression system, and power island. Finally, we illustrate the issues arising from the use of natural gas as a feedstock for heat and power, and suggest directions to pursue for further analysis and process improvements, which we consider imperative to make this DAC process a viable option for large-scale CO 2 removal toward IPCC targets.", "year": 2022, "publicationDate": "2022-03-01", "publicationTypes": [], "venue": "Cell Reports Physical Science", "journal": {"name": "Cell Reports Physical Science"}, "citationCount": 20, "referenceCount": 24, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S2666386422000583/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2158291726", "name": "Ryan Long-Innes"}, {"authorId": "2425346", "name": "H. Struchtrup"}], "url": "https://www.semanticscholar.org/paper/835b020246c9ee0541a682ebd72cd924626e27c8", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "76de0026b0ed90ec5d91cedd22dc9dee9cbcb7d6", "title": "Facile Fabrication of Monodispersed Carbon Sphere: A Pathway Toward Energy-Efficient Direct Air Capture (DAC) Using Amino Acids.", "abstract": "Direct removal of carbon dioxide (CO2 ) from the atmosphere, known as direct air capture (DAC) is attracting worldwide attention as a negative emission technology to control atmospheric CO2 concentrations. However, the energy-intensive nature of CO2 absorption-desorption processes has restricted deployment of DAC operations. Catalytic solvent regeneration is an effective solution to tackle this issue by accelerating CO2 desorption at lower regeneration temperatures. This work reports a one-step synthesis methodology to prepare monodispersed carbon nanospheres (MCSs) using trisodium citrate as a structure-directing agent with acidic sites. The assembly of citrate groups on the surface of MCSs enables consistent spherical growth morphology, reduces agglomeration and enhances water dispersibility. The functionalization-assisted synthesis produces uniform, hydrophilic nanospheres of 100-600 nm range. This work also demonstrates that the prepared MCSs can be further functionalized with strong Brønsted acid sites, providing high proton donation ability. Furthermore, the materials can be effectively used in a wide range of amino acid solutions to substantially accelerate CO2 desorption (25.6% for potassium glycinate and 41.1% for potassium lysinate) in the DAC process. Considering the facile synthesis of acidic MCSs and their superior catalytic efficiency, these findings are expected to pave a new path for energy-efficient DAC.", "year": 2023, "publicationDate": "2023-04-14", "publicationTypes": ["JournalArticle"], "venue": "Small", "journal": {"name": "Small", "pages": "\n          e2300150\n        "}, "citationCount": 19, "referenceCount": 44, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/smll.202300150", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "96944121", "name": "M. Alivand"}, {"authorId": "41092644", "name": "Rebecca V. McQuillan"}, {"authorId": "2133055882", "name": "Arash Momeni"}, {"authorId": "2331243655", "name": "Ali Zavabeti"}, {"authorId": "2061536923", "name": "Geoffrey W. Stevens"}, {"authorId": "92448275", "name": "K. Mumford"}], "url": "https://www.semanticscholar.org/paper/76de0026b0ed90ec5d91cedd22dc9dee9cbcb7d6", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "efac2a73c8986dfa518a0f560e377958648cc980", "title": "Direct Air Capture (DAC) for Achieving Net-Zero CO2 Emissions: Advances, Applications, and Challenges", "abstract": "Carbon dioxide (CO2), as the primary greenhouse gas, has significant impacts on global climate change, leading to severe and irreversible adverse consequences for ecosystems and human environments. To address the issue of excessive CO2 emissions, efforts in recent years have yielded significant progress in the development of clean energy sources and the promotion of carbon capture, utilization, and storage (CCUS) technologies. Conventional CO2 capture techniques are limited in addressing global atmospheric CO2 excess effectively, as they target only high-concentration CO2 emissions and require implementation at specific emission points. Direct air capture (DAC) technology has emerged as a promising solution due to its flexibility in deployment, avoidance of land competition, and ability to capture legacy CO2 emissions. Additionally, DAC offers opportunities for producing synthetic clean fuels, thereby reducing reliance on traditional fossil fuels and aiding in reducing greenhouse gas emissions. This study provides a comprehensive review of DAC technology, encompassing its principles, technological advancements, real-world applications, challenges, and future research directions. By offering insights into the current state and potential of DAC technology, this study aims to guide global efforts in scaling up DAC deployment, ultimately contributing to achieving global carbon neutrality or even negative emissions.", "year": 2024, "publicationDate": "2024-07-04", "publicationTypes": ["JournalArticle", "Review"], "venue": "Engineer", "journal": {"name": "Eng"}, "citationCount": 44, "referenceCount": 198, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2673-4117/5/3/69/pdf?version=1720097329", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2108696639", "name": "Guiheng Li"}, {"authorId": "2267923118", "name": "Jia Yao"}], "url": "https://www.semanticscholar.org/paper/efac2a73c8986dfa518a0f560e377958648cc980", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "58f9b2b9c5636f0a958c4fc2819800eacc2d4770", "title": "Measuring and Modeling Water and Carbon Dioxide Adsorption on Amine Functionalized Alumina under Direct Air Capture Conditions", "abstract": "Water vapor is an unavoidable component of ambient air that sorbents designed for atmospheric CO2 capture must contend with. Amine functionalized sorbents often exhibit an enhancement of CO2 uptake in the presence of moisture through a variety of mechanisms, and in this work, we investigate the coadsorption of water and CO2 on amine functionalized alumina. Sorbent performance is examined under varying levels of humidity and temperature using three common measurement techniques: gravimetric, volumetric, and breakthrough methods. Our findings show that water increasingly enhances CO2 adsorption up to the monolayer saturation point of water, above which no further enhancement is observed. Competitive adsorption is observed primarily at low relative humidities, and a novel dual-site isotherm model is developed that successfully describes these behaviors. Additionally, this study highlights the unique advantages of each measurement technique for accurately characterizing sorbent performance under direct air capture (DAC) conditions. These insights contribute to the understanding and optimization of amine-based sorbents in DAC applications.", "year": 2025, "publicationDate": "2025-03-19", "publicationTypes": ["JournalArticle"], "venue": "Industrial & Engineering Chemistry Research", "journal": {"name": "Industrial & Engineering Chemistry Research", "pages": "7165 - 7175", "volume": "64"}, "citationCount": 18, "referenceCount": 55, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1021/acs.iecr.4c04581", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2231844521", "name": "Quirin Grossmann"}, {"authorId": "2037021355", "name": "Paola A. Saenz-Cavazos"}, {"authorId": "2196794023", "name": "Nicole Ferru"}, {"authorId": "2316508748", "name": "Daryl R. Williams"}, {"authorId": "2237271796", "name": "Marco Mazzotti"}], "url": "https://www.semanticscholar.org/paper/58f9b2b9c5636f0a958c4fc2819800eacc2d4770", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "82a9f3b7444d249bf48787722e6822e640ff25b1", "title": "A review of direct air capture (DAC): scaling up commercial technologies and innovating for the future", "abstract": "Direct air capture (DAC) can provide an impactful, engineered approach to combat climate change by removing carbon dioxide (CO2) from the air. However, to meet climate goals, DAC needs to be scaled at a rapid rate. Current DAC approaches use engineered contactors filled with chemicals to repeatedly capture CO2 from the air and release high purity CO2 that can be stored or otherwise used. This review article focuses on two distinctive, commercial DAC processes to bind with CO2: solid sorbents and liquid solvents. We discuss the properties of solvents and sorbents, including mass transfer, heat transfer and chemical kinetics, as well as how these properties influence the design and cost of the DAC process. Further, we provide a novel overview of the considerations for deploying these DAC technologies, including concepts for learning-by-doing that may drive down costs and material requirements for scaling up DAC technologies.", "year": 2021, "publicationDate": "2021-03-24", "publicationTypes": ["Review"], "venue": "Progress in Energy", "journal": {"name": "Progress in Energy", "volume": "3"}, "citationCount": 553, "referenceCount": 109, "influentialCitationCount": 16, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1088/2516-1083/abf1ce", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1572251171", "name": "N. McQueen"}, {"authorId": "2087926999", "name": "Katherine Vaz Gomes"}, {"authorId": "48757067", "name": "Colin McCormick"}, {"authorId": "151070820", "name": "Katherine Blumanthal"}, {"authorId": "1583576447", "name": "Max Pisciotta"}, {"authorId": "145008880", "name": "J. Wilcox"}], "url": "https://www.semanticscholar.org/paper/82a9f3b7444d249bf48787722e6822e640ff25b1", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "e4987980374fbf3bedac84987a19a146a001dd55", "title": "A new relevant membrane application: CO2 direct air capture (DAC)", "abstract": "Since carbon dioxide (CO2) is the primary greenhouse gas emitted due to human activities into the atmosphere, strong research efforts have been developed towards capturing and 2 decreasing its production. Unfortunately, specific processes and activities make it impossible to avoid CO2 emissions. Among the different strategies scientists propose for CO2 reduction, direct CO2 capture from the atmosphere, also known as direct air capture (DAC), represents a promising alternative in which sorbents have been mainly used. Recently, gas separation membranes have also been speculated to carry out such a separation, thanks to their smaller footprint and simpler setup and operation; however, their application remains a proposition in the field. This paper gives a perspective of the ongoing research and attempts of DAC applications via membrane separation and introduces the main membrane materials and types used for CO2 separation. Finally, the process considerations for DAC using membranes are stated to guide the new researchers in the field.", "year": 2022, "publicationDate": "2022-05-01", "publicationTypes": [], "venue": "Chemical Engineering Journal", "journal": {"name": "Chemical Engineering Journal"}, "citationCount": 196, "referenceCount": 150, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.cej.2022.137047", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1403195847", "name": "Roberto Castro-Muñoz"}, {"authorId": "2135060455", "name": "Mohd Zamidi Ahmad"}, {"authorId": "30728327", "name": "Magdalena Malankowska"}, {"authorId": "145420589", "name": "J. Coronas"}], "url": "https://www.semanticscholar.org/paper/e4987980374fbf3bedac84987a19a146a001dd55", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "c8a1bbfdc2d3bd0674e804f12b9b3e90e3da62f4", "title": "Distributed direct air capture by carbon nanofiber air filters", "abstract": "The rising atmospheric CO2 concentration is one of the biggest challenges human civilization faces. Direct air capture (DAC) that removes CO2 from the atmosphere provides great potential in carbon neutralization. However, the massive land use and capital investment of centralized DAC plants and the energy-intensive process of adsorbent regeneration limit its wide employment. We develop a distributed carbon nanofiber (CNF)–based DAC air filter capable of adsorbing CO2 downstream in ventilation systems. The DAC air filter not only has the potential to remove 596 MtCO2 year−1 globally but can also decrease energy consumption in existing building systems. The CNF-based adsorbent has a capacity of 4 mmol/g and can be regenerated via solar thermal or electrothermal methods with low carbon footprints. Through life cycle assessment, the CNF air filter shows a carbon removal efficiency of 92.1% from cradle to grave. Additionally, techno-economic analysis estimates a cost of $209 to 668 in capturing and storing 1 tonne of CO2 from direct air.", "year": 2025, "publicationDate": "2025-10-17", "publicationTypes": ["JournalArticle"], "venue": "Science Advances", "journal": {"name": "Science Advances", "volume": "11"}, "citationCount": 12, "referenceCount": 81, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2237093078", "name": "Ronghui Wu"}, {"authorId": "2361351450", "name": "Hernan E. Delgado"}, {"authorId": "2280862560", "name": "Yi Xie"}, {"authorId": "2362352190", "name": "Yuanke Chen"}, {"authorId": "2314943580", "name": "Gangbin Yan"}, {"authorId": "2306245025", "name": "Edward Luo"}, {"authorId": "2282788062", "name": "Qizhang Li"}, {"authorId": "2304757580", "name": "Qingsong Fan"}, {"authorId": "2277744246", "name": "Yu Han"}, {"authorId": "2121404011", "name": "Genesis Higueros"}, {"authorId": "2360113777", "name": "Amar Ruthen"}, {"authorId": "51139540", "name": "Chenxi Sui"}, {"authorId": "1391030157", "name": "Adarsh Suresh"}, {"authorId": "2302444021", "name": "David B. Mitzi"}, {"authorId": "2144923282", "name": "Chong Liu"}, {"authorId": "11785626", "name": "A. Elgowainy"}, {"authorId": "2057582421", "name": "Po‐Chun Hsu"}], "url": "https://www.semanticscholar.org/paper/c8a1bbfdc2d3bd0674e804f12b9b3e90e3da62f4", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "bb420cff79c1ea51ddad53d691363d3963f1407e", "title": "Direct air capture-assisted sustainable fuel solution in maritime sector: a carbon footprint perspective", "abstract": "Carbon emissions reduction within the maritime sector is pivotal for realizing zero-carbon goals and mitigating climate impacts. Adopting renewable carbon fuels presents a potent strategy. It is necessary to have a comprehensive understanding of its negative carbon attributes and enduring contributions to future development based on carbon footprint assessment. By using the CO2 captured through direct air capture (DAC) technology and the H2 obtained via water electrolysis as feedstock, electro-methanol (e-methanol) can be produced under renewable energy-driven conditions. Owing to the environmental benefits and economic feasibility of e-methanol, we highlight its potential as a practical alternative to traditional fossil fuel-based technical scenarios. A quantitative analysis of this integrated system from a carbon footprint perspective allows for an environmental sustainability assessment. According to predictions, scaled-up usage of the system can reduce the maritime sector's contribution to global carbon emissions by half by 2050. ∙ Using CO2 from DAC and H2 from water electrolysis, e-methanol can be produced and used within the maritime sector. ∙ A quantitative analysis from a carbon footprint perspective allows for an environmental sustainability assessment. ∙ Scaled-up usage of the system can reduce the maritime sector's contribution to global carbon emissions by half by 2050.", "year": 2025, "publicationDate": "2025-05-16", "publicationTypes": ["JournalArticle"], "venue": "Carbon Research", "journal": {"name": "Carbon Research", "volume": "4"}, "citationCount": 10, "referenceCount": 103, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s44246-025-00209-5.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2355028843", "name": "Shuangjun Li"}, {"authorId": "2278772780", "name": "Zhenyu Du"}, {"authorId": "2278193130", "name": "Junyao Wang"}, {"authorId": "2361655221", "name": "Hao Wang"}, {"authorId": "2327596854", "name": "Xiangkun Elvis Cao"}, {"authorId": "2302995250", "name": "Runkai Chen"}, {"authorId": "2370631661", "name": "Yujia Pang"}, {"authorId": "2152244676", "name": "Shuai Deng"}, {"authorId": "2278111367", "name": "Ondřej Mašek"}, {"authorId": "2239167728", "name": "Xiangzhou Yuan"}, {"authorId": "2290691099", "name": "Ki Bong Lee"}], "url": "https://www.semanticscholar.org/paper/bb420cff79c1ea51ddad53d691363d3963f1407e", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "10a671de0516b753088022bd365ddee2af3bd1c1", "title": "Water-Enhanced Direct Air Capture of Carbon Dioxide in Metal-Organic Frameworks.", "abstract": "We have developed two series of amine-functionalized zirconium (Zr) metal-organic framework-808 (MOF-808), which were produced by postsynthetic modifications to have either amino acids coordinated to Zr ions (MOF-808-AAs) or polyamines covalently bound to the chloro-functionalized structure (MOF-808-PAs). These MOF variants were comprehensively characterized by liquid-state 1H nuclear magnetic resonance (NMR) measurements and potentiometric acid-base titration to determine the amounts of amines, energy-dispersive X-ray spectroscopy to assess the extent of covalent substitution by polyamines, powder X-ray diffraction analysis to verify the maintenance of the MOF crystallinity and structure after postsynthetic modifications, nitrogen sorption isotherm measurements to confirm retention of the porosity, and water sorption isotherm measurements to find the water uptake in the pores of each member of the series. Evaluation and testing of these compounds in direct air capture (DAC) of CO2 showed improved CO2 capture performance for the functionalized forms, especially under humid conditions: In dry conditions, the l-lysine- and tris(3-aminopropyl)amine-functionalized variants, termed as MOF-808-Lys and MOF-808-TAPA, exhibited the highest CO2 uptakes at 400 ppm, measuring 0.612 and 0.498 mmol g-1, and further capacity enhancement was achieved by introducing 50% relative humidity, resulting in remarkable uptakes of 1.205 and 0.872 mmol g-1 corresponding to 97 and 75% increase compared to the dry uptakes, respectively. The mechanism underlying the enhanced uptake efficiency was revealed by 13C solid-state NMR and temperature-programmed desorption measurements, indicating the formation of bicarbonate species, and therefore a stoichiometry of 1:1 CO2 to each amine site.", "year": 2024, "publicationDate": "2024-01-18", "publicationTypes": ["JournalArticle"], "venue": "Journal of the American Chemical Society", "journal": {"name": "Journal of the American Chemical Society"}, "citationCount": 185, "referenceCount": 36, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://hdl.handle.net/10481/107570", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2279894964", "name": "O. Chen"}, {"authorId": "2269827156", "name": "Cheng Liu"}, {"authorId": "2175028395", "name": "Kaiyu Wang"}, {"authorId": "2270619082", "name": "Emilio Borrego-Marin"}, {"authorId": "2280064961", "name": "Haozhe Li"}, {"authorId": "95500833", "name": "Ali H. Alawadhi"}, {"authorId": "2248170636", "name": "Jorge A. R. Navarro"}, {"authorId": "2248367257", "name": "O. Yaghi"}], "url": "https://www.semanticscholar.org/paper/10a671de0516b753088022bd365ddee2af3bd1c1", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "b033a5d05422ede399b79a8bd1e29e7fb805b372", "title": "Distributed direct air capture of carbon dioxide by synergistic water harvesting", "abstract": "Adsorption-based direct air capture (DAC) of carbon dioxide, using chemisorbents like solid amines, has been widely recognized as a sustainable measure to contain atmospheric CO2 concentrations. However, the productivity and economic viability of DAC have been compromised by the high energy consumption for regenerating the adsorbents. Here, we show that by synergistically harvesting water and carbon dioxide from the atmosphere, we can regenerate the unit using in situ vapor purge at low energy and capital cost. The desorption of CO2 is substantially enhanced in the presence of concentrated water vapors at around 100 °C, concurrently producing 97.7% purity CO2 and fresh water without the use of vacuum pumps and steam boilers. Moreover, we demonstrate that the DAC prototype can also be powered by sunlight, which recovers 98% of the adsorbed CO2, with 20% less energy demand, enabling sustainable carbon capture from air in a real distributed manner. Direct air capture of CO2 suffers from high energy consumption. Here, the authors use co-harvested water as in situ vapor purge to regenerate the sorbents, achieving over 98% recovery of the adsorbed CO2, more than 20% reduction in energy penalty, and synergistic production of CO2 and water.", "year": 2024, "publicationDate": "2024-11-11", "publicationTypes": ["JournalArticle"], "venue": "Nature Communications", "journal": {"name": "Nature Communications", "volume": "15"}, "citationCount": 55, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s41467-024-53961-4.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2318930262", "name": "Yongqiang Wang"}, {"authorId": "2301280497", "name": "Longbing Qu"}, {"authorId": "2238920108", "name": "Hui Ding"}, {"authorId": "2330335638", "name": "Paul A. Webley"}, {"authorId": "38278413", "name": "G. Li"}], "url": "https://www.semanticscholar.org/paper/b033a5d05422ede399b79a8bd1e29e7fb805b372", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "27213ea88265365870d910f6baa4781e4276445d", "title": "A Comparative Study of Different Sorbents in the Context of Direct Air Capture (DAC): Evaluation of Key Performance Indicators and Comparisons", "abstract": "Direct air capture can be based on an adsorption system, and the used sorbent (chemisorbents or physisorbents) influences process. In this work, two amine-functionalized sorbents, as chemisorbents, and three different metal organic frameworks, as physisorbents, are considered and compared in terms of some key performance indicators. This was carried out by developing a mathematical model describing the adsorption and desorption stages. An independent analysis was carried out in order to verify data reported in the literature. Results show that the equilibrium loading is a critical parameter for adsorption capacity, energy consumption, and cost. The considered metal organic frameworks are characterized by a lower equilibrium loading (10−4 mol/kg) compared to chemisorbents (10−1 mol/kg). For this reason, physisorbents have higher overall energy consumptions and costs, while capturing a lower amount of carbon dioxide. A reasonable agreement is found on the basis of the operating conditions of the Climeworks company, modelling the use of the same amine cellulose-based sorbent. The same order of magnitude is found for total costs (751 USD/tonneCO2 for our analysis, compared to the value of 600 USD/tonneCO2 proposed by this company).", "year": 2022, "publicationDate": "2022-03-03", "publicationTypes": [], "venue": "Applied Sciences", "journal": {"name": "Applied Sciences"}, "citationCount": 70, "referenceCount": 107, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2076-3417/12/5/2618/pdf?version=1646299419", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "88875862", "name": "Grazia Leonzio"}, {"authorId": "144426641", "name": "P. Fennell"}, {"authorId": "2114061811", "name": "Nilay Shah"}], "url": "https://www.semanticscholar.org/paper/27213ea88265365870d910f6baa4781e4276445d", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "09d8422694a7debf4943ea644facd7f5379442e6", "title": "Direct air capture integration with low-carbon heat: Process engineering and power system analysis", "abstract": "Direct air capture (DAC) of carbon dioxide (CO 2 ) is energy intensive given the low concentration ( < 0.1%) of CO 2 in ambient air, but offers relatively strong verification of removals and limited land constraints to scale. Lower temperature solid sorbent based DAC could be coupled on-site with low carbon thermal generators such as nuclear power plants. Here, we undertake a unique interdisciplinary study combining process engineering with a detailed macro-energy system optimization model to evaluate the system-level impacts of such plant designs in the Texas electricity system. We contrast this with using grid power to operate a heat pump to regenerate the sorbent. Our analysis identifies net carbon removal costs accounting for power system impacts and resulting indirect CO 2 emissions from DAC energy consumption. We find that inefficient configurations of DAC at a nuclear power plant can lead to increases in power sector emissions relative to a case without DAC, at a scale that would cancel out almost 50% of the carbon removal from DAC. Net removal costs for the most efficient configurations increase by roughly 18% once indirect power system-level impacts are considered, though this is comparable to the indirect systems-level emissions from operating grid-powered heat pumps for sorbent regeneration. Our study therefore highlights the need for DAC energy procurement to be guided by consideration of indirect emission impacts on the electricity system. Finally, DAC could potentially create demand pull for zero carbon firm generation, accelerating decarbonization relative to a world without such DAC deployment. We find that DAC operators would have to be willing to pay existing or new nuclear power plants roughly $30–80/tCO 2 or $150–400/tCO 2 respectively, for input energy, to enable nuclear plants to be economically competitive in least cost electricity markets that do not have carbon constraints or subsidies for nuclear energy.", "year": 2024, "publicationDate": "2024-12-01", "publicationTypes": ["JournalArticle"], "venue": "Energy Conversion and Management", "journal": {"name": "Energy Conversion and Management"}, "citationCount": 16, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.enconman.2024.119136", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "118208274", "name": "Aniruddh Mohan"}, {"authorId": "2298109738", "name": "Fangwei Cheng"}, {"authorId": "2266127247", "name": "Hongxi Luo"}, {"authorId": "2265167105", "name": "Chris Greig"}, {"authorId": "2273956575", "name": "Eric D. Larson"}, {"authorId": "2267083268", "name": "Jesse D. Jenkins"}], "url": "https://www.semanticscholar.org/paper/09d8422694a7debf4943ea644facd7f5379442e6", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "10534e06df7c08965899d398816ec57edbd10e35", "title": "Activated Carbon Fiber Felt Composites for the Direct Air Capture of Carbon Dioxide.", "abstract": "Negative emission technologies to mitigate climate change require innovative solutions for the direct air capture (DAC) of CO2 from the atmosphere. K2CO3 readily reacts with CO2 to form KHCO3; however, bulk K2CO3 suffers from very slow sorption kinetics. By incorporating K2CO3 into activated carbon (AC) fiber felts, the sorption kinetics were significantly improved by increasing the surface area of K2CO3 in contact with air. The AC-K2CO3 fiber composite felts are flexible, cheap, easy to manufacture, chemically stable, and show excellent DAC capacity and (de)sorption rates, with stable performance up to ten cycles. Cyclic testing was demonstrated with 4 h sorption and 0.5 h desorption intervals. The best composite felts collected an average of 478 µmol of CO2 per gram of composite during 4 h of exposure to ambient air (19% relative humidity) that had a CO2 concentration of 400-450 ppm after regeneration at 125 °C in an air furnace. An increase in the dew point temperature from 0 °C to 12 °C decreased sorption performance of the composite felts by 40%.", "year": 2024, "publicationDate": "2024-09-21", "publicationTypes": ["JournalArticle"], "venue": "ChemSusChem", "journal": {"name": "ChemSusChem", "pages": "\n          e202401188\n        "}, "citationCount": 14, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2128524364", "name": "Mani Modayil Korah"}, {"authorId": "2613070", "name": "K. Culp"}, {"authorId": "2322083026", "name": "Klaus S. Lackner"}, {"authorId": "2322419367", "name": "Matthew D Green"}], "url": "https://www.semanticscholar.org/paper/10534e06df7c08965899d398816ec57edbd10e35", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "c9131d124a3cd50bc44af0cbc41ba8564b30c20c", "title": "Study of Direct Air Capture (DAC) Using a KOH/K2CO3 Absorbing Solution for CO2 Capture", "abstract": "Direct Air Capture (DAC) consists of sequestrating CO 2 from ambient air using absorption or adsorption mechanisms. Within the former, alkaline solutions, such as KOH, are generally used as the absorbing agent due to the high reached pH values favouring CO 2 absorption. However, these solutions' alkalinity induces high corrosivity and harmful properties, making them challenging to handle. The KOH/K 2 CO 3 mixture solution is studied in this paper and proposed as an alternative to the more generally used strong base solution. This mixture solution aims at taking advantage of the low toxicity and corrosivity of K 2 CO 3 solutions while still including a fraction of KOH. It guarantees sufficiently high alkalinity and counteracts K 2 CO 3 poor mass transfer performance. The purpose of this paper is to have first estimations of the potential of KOH/K 2 CO 3 solutions as the absorbing agent for carbon capture in ambient air by taking only equilibrium considerations and assuming an ideal aqueous solution. Within this framework, CO 2 removal efficiencies are calculated for various pH values and phase ratios, and then the results are compared with literature data. This comparison highlights the importance of kinetics limitations for CO 2 absorption in aqueous solutions. A significant part of this work is focused on the potential precipitation issues that may occur during CO 2 absorption. These issues’ likelihood is compared for the case of a KOH/K 2 CO 3 and a NaOH/K 2 CO 3 solution. It turns out that precipitation is only encountered in the latter situation when extreme concentration conditions are encountered. In further work, the results should be refined by including the absorption kinetics and appropriately modelling the aqueous phase, accounting for the existing interactions. These factors may influence the conditions under which precipitation occurs. Nevertheless, the present study gives the necessary thermodynamics fundamental knowledge for addressing the challenges to be encountered in KOH/K 2 CO 3 solutions.", "year": 2022, "publicationDate": null, "publicationTypes": [], "venue": "Social Science Research Network", "journal": {"name": "SSRN Electronic Journal"}, "citationCount": 11, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.2139/ssrn.4273837", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2190635749", "name": "Antoine Rouxhet"}, {"authorId": "2109699327", "name": "So-mang Kim"}, {"authorId": "33056900", "name": "Grégoire Léonard"}], "url": "https://www.semanticscholar.org/paper/c9131d124a3cd50bc44af0cbc41ba8564b30c20c", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "5b1c92b04a562f390ac4650fbd016e0922a3490e", "title": "Architecting Metal-Organic Frameworks at Molecular Level toward Direct Air Capture.", "abstract": "Escalating carbon dioxide (CO2) emissions have intensified the greenhouse effect, posing a significant long-term threat to environmental sustainability. Direct air capture (DAC) has emerged as a promising approach to achieving a net-zero carbon future, which offers several practical advantages, such as independence from specific CO2 emission sources, economic feasibility, flexible deployment, and minimal risk of CO2 leakage. The design and optimization of DAC sorbents are crucial for accelerating industrial adoption. Metal-organic frameworks (MOFs), with high structural order and tunable pore sizes, present an ideal solution for achieving strong guest-host interactions under trace CO2 conditions. This perspective highlights recent advancements in using MOFs for DAC, examines the molecular-level effects of water vapor on trace CO2 capture, reviews data-driven computational screening methods to develop a molecularly programmable MOF platform for identifying optimal DAC sorbents, and discusses scale-up and cost of MOFs for DAC.", "year": 2025, "publicationDate": "2025-02-07", "publicationTypes": ["Review", "JournalArticle"], "venue": "Journal of the American Chemical Society", "journal": {"name": "Journal of the American Chemical Society"}, "citationCount": 70, "referenceCount": 99, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2343692105", "name": "Zi-Ming Ye"}, {"authorId": "2268851849", "name": "Yi Xie"}, {"authorId": "5282821", "name": "Kent O. Kirlikovali"}, {"authorId": "2244268395", "name": "Shengchang Xiang"}, {"authorId": "5385033", "name": "O. Farha"}, {"authorId": "2244574113", "name": "Banglin Chen"}], "url": "https://www.semanticscholar.org/paper/5b1c92b04a562f390ac4650fbd016e0922a3490e", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "dea4e7f99c0894db1e80b26cb8c7026fbb394174", "title": "Microwave regeneration and thermal and oxidative stability of imidazolium cyanopyrrolide ionic liquid for direct air capture of carbon dioxide.", "abstract": "Understanding the oxidative and thermal degradation of CO2 sorbents is essential for assessing long-term sorbent stability in direct air capture (DAC). The potential degradation pathway of imidazolium cyanopyrrolide, an ionic liquid (IL) functionalized for superior CO2 capacity and selectivity, was evaluated under accelerated degradation conditions to understand the secondary reactions that can occur during repetitive absorption-desorption thermal-swing cycles. The combined analysis from various spectroscopy, chromatography, and thermal gravimetric measurements indicated that radicalic and SN2 mechanisms in degradation are encouraged by the nucleophilicity of the anion. Thickening of the liquid and gas evolution are accompanied by 50% reduction in CO2 capacity after a 7-day exposure to O2 under 80 °C. In order to prevent long exposure to conventional thermal heating, we demonstrate microwave (MW) regeneration of the CO2-reactive IL where dielectric heating at 80 and 100 °C rapidly desorbs CO2 and regenerates the IL without any measurable degradation.", "year": 2023, "publicationDate": "2023-03-13", "publicationTypes": ["JournalArticle"], "venue": "ChemSusChem", "journal": {"name": "ChemSusChem", "pages": "\n          e202300118\n        "}, "citationCount": 25, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cssc.202300118", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "91940421", "name": "Yun-Yang Lee"}, {"authorId": "89562245", "name": "Eda Çağli"}, {"authorId": "1606705351", "name": "Aidan Klemm"}, {"authorId": "1979208", "name": "Yensil Park"}, {"authorId": "2182595563", "name": "Ruth Dikki"}, {"authorId": "144498523", "name": "M. Kidder"}, {"authorId": "2244459944", "name": "Burcu Gurkan"}], "url": "https://www.semanticscholar.org/paper/dea4e7f99c0894db1e80b26cb8c7026fbb394174", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "c1d27d49141762d217b5eec771a7fed2156274ab", "title": "Advancements and Challenges in Direct Air Capture Technologies: Energy Intensity, Novel Methods, Economics, and Location Strategies", "abstract": "Direct air capture (DAC) technology is increasingly recognized as a key tool in the pursuit of climate neutrality, enabling the removal of carbon dioxide directly from the atmosphere. Despite its potential, DAC remains in the early stages of development, with most installations limited to pilot or demonstration units. The main barriers to its widespread implementation include high energy demands and significant capture costs. This literature review addresses the most critical research directions related to the development of this technology, focusing on its challenges and prospects for deployment. Particular attention is given to studies aimed at developing new, cost-effective, and efficient sorbents that could significantly reduce the energy intensity and costs of the process. Alternative technologies, such as electrochemical and membrane-based processes, show promise but require further research to overcome limitations, such as sensitivity to oxygen presence or insufficient membrane selectivity. The economic feasibility of DAC remains uncertain, with current estimates subject to significant uncertainty. Governmental and regulatory support will be crucial for the technology’s success. Furthermore, the location of DAC installations should consider factors such as energy availability, options for carbon dioxide storage or utilization, and climatic conditions, which significantly affect process efficiency. This review highlights the necessity for continued research to overcome existing barriers and fully harness the potential of DAC technology.", "year": 2025, "publicationDate": "2025-01-22", "publicationTypes": ["JournalArticle", "Review"], "venue": "Energies", "journal": {"name": "Energies"}, "citationCount": 29, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/1996-1073/18/3/496/pdf?version=1737554900", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2298681784", "name": "Janusz Kotowicz"}, {"authorId": "2281568078", "name": "Kamil Niesporek"}, {"authorId": "2281559627", "name": "Oliwia Baszczeńska"}], "url": "https://www.semanticscholar.org/paper/c1d27d49141762d217b5eec771a7fed2156274ab", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "0d9251394c0f56bb9f72be1836b7b3884002c3fa", "title": "The role of direct air capture in achieving climate-neutral aviation", "abstract": "Growing demand for air travel and limited scalable solutions pose significant challenges to the mitigation of aviation’s climate change impact. Direct air capture (DAC) may gain prominence due to its versatile applications for either carbon removal (direct air carbon capture and storage, DACCS) or synthetic fuel production (direct air carbon capture and utilization, DACCU). Through a comprehensive and time-dynamic techno-economic assessment, we explore the conditions for synthetic fuels from DACCU to become cost-competitive with an emit-and-remove strategy based on DACCS under 2050 CO2 and climate neutrality targets. We find that synthetic fuels could achieve climate neutrality at lower cost than an emit-and-remove strategy due to their ability to cost-effectively mitigate contrails. Under demand reductions, contrail avoidance, and CO2 neutrality targets the cost advantage of synthetic fuels weakens or disappears. Low electricity cost (€0.02 kWh-1) and high fossil kerosene prices (€0.9 l-1) can favor synthetic fuels’ cost-competitiveness even under these conditions. Strategic interventions, such as optimal siting and the elimination of fossil fuel subsidies, can thus favor a shift away from fossil-reliant aviation. This study examines Direct Air Capture’s role in climate-neutral aviation via synthetic fuels or carbon removal. It finds Direct Air Capture-based fuels can cost-effectively mitigate CO₂ and non-CO₂ effects if cheap renewable energy is used.", "year": 2025, "publicationDate": "2025-01-11", "publicationTypes": ["JournalArticle"], "venue": "Nature Communications", "journal": {"name": "Nature Communications", "volume": "16"}, "citationCount": 27, "referenceCount": 113, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s41467-024-55482-6.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2056535706", "name": "Nicoletta Brazzola"}, {"authorId": "2339754432", "name": "Amir Meskaldji"}, {"authorId": "2295401053", "name": "Anthony Patt"}, {"authorId": "22247404", "name": "T. Tröndle"}, {"authorId": "2238313765", "name": "Christian Moretti"}], "url": "https://www.semanticscholar.org/paper/0d9251394c0f56bb9f72be1836b7b3884002c3fa", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "a57a7ea8110ecfb8ebc49965499a52b23ef5b61f", "title": "Carbonation of MgO Single Crystals: Implications for Direct Air Capture of CO2.", "abstract": "Direct air capture (DAC) may be feasible to remove carbon dioxide (CO2) from the atmosphere at the gigaton scale, holding promise to become a major contributor to climate change mitigation. Mineral looping using magnesium oxide (MgO) is potentially an economical, efficient, and sustainable pathway to gigaton-scale DAC. The hydroxylation and carbonation of MgO determine the efficiency of the looping process, but their rates and mechanisms remain uncertain. In this work, MgO single crystals were reacted in air or CO2 at varying humidities and characterized by X-ray scattering, microscopy, and vibrational spectroscopy. Results show that the hydroxylation formed a brucite (Mg(OH)2)-like layer immediately after crystal cleaving. Concurrently, the carbonation formed hydrated magnesium carbonate phases, including barringtonite (MgCO3·2H2O) and nesquehonite (MgCO3·2H2O), in the layer. Rapid initial growth of the layer is also manifested in short-range bending/warping of nanocrystallites, resulting in multiple orientations of the same phases on the surface. The layer growth slowed down over time, indicating surface passivation. The formation of barringtonite and nesquehonite with 1:1 CO3/Mg ratio indicates an efficient carbonation when compared to other magnesium carbonate phases of lower ratio. Our results are essential for understanding surface passivation mechanisms and tackling the passivation issue of mineral looping DAC technology.", "year": 2025, "publicationDate": "2025-02-10", "publicationTypes": ["JournalArticle"], "venue": "Environmental Science and Technology", "journal": {"name": "Environmental science & technology"}, "citationCount": 21, "referenceCount": 48, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.osti.gov/servlets/purl/2538136", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2239070801", "name": "Peng Yang"}, {"authorId": "13685638", "name": "Jacquelyn N. Bracco"}, {"authorId": "2277124644", "name": "Gabriela Camacho Meneses"}, {"authorId": "2057748506", "name": "Ke Yuan"}, {"authorId": "2270103174", "name": "Joanne E. Stubbs"}, {"authorId": "15811949", "name": "Mavis D. Boamah"}, {"authorId": "2237922877", "name": "M. Brahlek"}, {"authorId": "145593804", "name": "M. Sassi"}, {"authorId": "2261575311", "name": "P. Eng"}, {"authorId": "23583109", "name": "M. Boebinger"}, {"authorId": "2064085976", "name": "A. Borisevich"}, {"authorId": "146219196", "name": "Anna K. Wanhala"}, {"authorId": "2294390054", "name": "Zheming Wang"}, {"authorId": "2238275813", "name": "Kevin M. Rosso"}, {"authorId": "2271064734", "name": "A. Stack"}, {"authorId": "2243917976", "name": "J. Weber"}], "url": "https://www.semanticscholar.org/paper/a57a7ea8110ecfb8ebc49965499a52b23ef5b61f", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "d99a5c26d26aa2558a3a9da23e1e6dc70eb757a2", "title": "Perspective on distributed direct air capture: what, why, and how?", "abstract": "Direct air capture (DAC) is widely considered as a critical negative emission technology to not only mitigate but reverse global climate change. While commercially expanding, its efficiency is limited by energy-intensive sorbent regeneration. Here, we highlight distributed DAC as a complement to centralized systems, analyzing the regeneration energy demands and carbon footprints of various sorbents. A comprehensive evaluation of distributed DAC’s impact is crucial for maximizing its potential.", "year": 2025, "publicationDate": "2025-05-17", "publicationTypes": ["JournalArticle"], "venue": "npj Materials Sustainability", "journal": {"name": "npj Materials Sustainability", "volume": "3"}, "citationCount": 15, "referenceCount": 47, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s44296-025-00056-w.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2362352190", "name": "Yuanke Chen"}, {"authorId": "2354507014", "name": "Ronghui Wu"}, {"authorId": "2057582421", "name": "Po‐Chun Hsu"}], "url": "https://www.semanticscholar.org/paper/d99a5c26d26aa2558a3a9da23e1e6dc70eb757a2", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "de8b788bd5ec322d3cd4ff4a6c499aac171a9c47", "title": "Research needs targeting direct air capture of carbon dioxide: Material & process performance characteristics under realistic environmental conditions", "abstract": null, "year": 2022, "publicationDate": "2022-01-01", "publicationTypes": [], "venue": "Korean Journal of Chemical Engineering", "journal": {"name": "Korean Journal of Chemical Engineering", "pages": "1-19", "volume": "39"}, "citationCount": 86, "referenceCount": 124, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "145624136", "name": "Fanhe Kong"}, {"authorId": "9260782", "name": "G. Rim"}, {"authorId": "144982604", "name": "Min Song"}, {"authorId": "38154419", "name": "Cornelia Rosu"}, {"authorId": "144225341", "name": "P. Priyadarshini"}, {"authorId": "2832408", "name": "Ryan P. Lively"}, {"authorId": "2183931", "name": "M. Realff"}, {"authorId": "37378853", "name": "Christopher W. Jones"}], "url": "https://www.semanticscholar.org/paper/de8b788bd5ec322d3cd4ff4a6c499aac171a9c47", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "c807de39297277b195ae95c824eb9103d59e1a5b", "title": "Environmental, economic and social trade-offs of membrane-based direct air capture technologies integrated with CO2 conversion using life cycle assessment", "abstract": "Technological solutions to address climate change are coalescing around renewable energy deployment. Yet, the deployment of renewables alone may not be sufficient to restrict temperature increases in line with Paris Agreement targets. The emergence of carbon negative technologies to bridge this shortfall is needed and expected to overcome this gap. Among these technologies, direct air capture (DAC) is being deployed at multiple scales using various approaches. This study investigates membrane-based DAC integrated with subsequent carbon dioxide to carbon fuel conversion, i.e. , DAC with utilization (DAC-U). The DAC-U evaluation is undertaken holistically, beginning with a cradle-to-grave life cycle assessment, followed by economic feasibility scenario analysis and social acceptability analysis to establish acceptable deployment pricing and necessary policy interventions. This study reveals that, although the DAC-U represents a carbon negative capable technology with positive lifestyle and environmental outcomes, high capital costs present a significant barrier to deployment. To overcome this barrier, a robust policy regime including subsidies or fuel credits may be necessary. Further technological innovation and efficiency gains will also close this gap, meaning that the membrane-based DAC-U concept may play a role in achieving carbon neutrality goals in the near future.", "year": 2025, "publicationDate": "2025-01-01", "publicationTypes": ["JournalArticle"], "venue": "Journal of CO2 Utilization", "journal": {"name": "Journal of CO2 Utilization"}, "citationCount": 12, "referenceCount": 62, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.jcou.2024.103002", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2277190771", "name": "Tianhui Fan"}, {"authorId": "2072820278", "name": "Siyu Shen"}, {"authorId": "2335942814", "name": "Chun Yat Sit"}, {"authorId": "2802710", "name": "P. Kenis"}, {"authorId": "2277223414", "name": "Andrew Chapman"}], "url": "https://www.semanticscholar.org/paper/c807de39297277b195ae95c824eb9103d59e1a5b", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "ce325bf4c0328494a8b12f98878ce3284af2bf04", "title": "Economically viable geological CO2 storage from direct air capture has critical threshold of 70% CO2 concentration", "abstract": "Direct Air Capture (DAC), a key component of Carbon Capture and Storage (CCS), has been widely studied. However, its large-scale deployment is hindered by the high energy cost of purifying captured CO2. Using impure CO2 can reduce energy consumption and overall costs, but it also lowers storage efficiency. This work employs molecular dynamics simulations to examine storage efficiency by analyzing the impurity systems’ density across a wide temperature and pressure range. The results indicate a strong similarity between the density changes at the macroscopic level and the Van der Waals interaction changes at the molecular level. Additionally, the Normalized Storage Efficiency caused by Impurities (NSEI) is proposed, which can be used for storage potential and cost evaluation. A detailed NSEI analysis suggests that CO2 concentration should reach at least 70% to achieve economically viable storage. This finding provides practical guidance for DAC capture system design and impurity CCS project planning. Le Zhang and colleagues propose that a 70% concentration should be met for economically viable geological storage of carbon dioxide from Direct Air Capture (DAC). This finding provides practical guidance for DAC system design and impurity carbon capture and storage project planning.", "year": 2025, "publicationDate": "2025-07-15", "publicationTypes": ["JournalArticle"], "venue": "Communications Engineer", "journal": {"name": "Communications Engineering", "volume": "4"}, "citationCount": 11, "referenceCount": 67, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2242947712", "name": "Le Zhang"}, {"authorId": "2117875610", "name": "Yunfeng Liang"}, {"authorId": "46984867", "name": "A. Kioka"}, {"authorId": "2240476643", "name": "Takeshi Tsuji"}], "url": "https://www.semanticscholar.org/paper/ce325bf4c0328494a8b12f98878ce3284af2bf04", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "d5d8fbadab25c07d0d73761aa87580727d547cf6", "title": "Integrated direct air CO2 capture and utilization via in-situ catalytic conversion to fuels and chemicals using dual functional materials: Recent progresses and perspectives", "abstract": null, "year": 2025, "publicationDate": "2025-01-10", "publicationTypes": ["JournalArticle", "Review"], "venue": "Frontiers in Energy", "journal": {"name": "Frontiers in Energy", "pages": "586 - 598", "volume": "19"}, "citationCount": 10, "referenceCount": 50, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "46866916", "name": "Yiran Zhang"}, {"authorId": "2278385626", "name": "Jiaqi Feng"}, {"authorId": "2278387909", "name": "Linjia Li"}, {"authorId": "2265444931", "name": "Shu Zhao"}, {"authorId": "144459104", "name": "C. Wu"}, {"authorId": "2279159286", "name": "Zhen Huang"}, {"authorId": "2156502210", "name": "He Lin"}], "url": "https://www.semanticscholar.org/paper/d5d8fbadab25c07d0d73761aa87580727d547cf6", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "e5dae63bdd8f0f337f3bdcd9985a53cb88c5c665", "title": "Carbon Capture from Natural Gas Flue Emissions and Air via (Bi)Carbonate Formation in a Cyclodextrin-Based Metal-Organic Framework.", "abstract": "Carbon capture and utilization or sequestration (CCUS) from industrial point sources and direct air capture (DAC) are both necessary to curb the rising atmospheric levels of CO2. Amine scrubbers, the current leading carbon capture technology, suffer from poor oxidative and thermal stability, limiting their long-term cycling stability under oxygen-rich streams such as air and the emissions from natural gas combined cycle (NGCC) power plants. Herein, we demonstrate that the hydroxide-based cyclodextrin metal-organic framework (CD-MOF) Rb2CO3 CD-MOF ST possesses high CO2 capacities from dry dilute streams at low temperatures and humid streams at elevated temperatures. Additionally, it displays good thermal, oxidative, and cycling stabilities and selective CO2 capture under mixed gas conditions in dynamic breakthrough experiments. Unexpectedly, under dry, hot conditions, a shift in the CO2 adsorption mechanism─from reversibly formed bicarbonate to irreversibly formed carbonate─is observed, as supported by gas sorption and spectroscopic studies coupled with density functional theory (DFT) calculations. This mechanistic switch, akin to urea formation in amine-functionalized sorbents, has not been previously reported in a hydroxide-based material and sheds new light on the interplay between bicarbonate and carbonate species during CO2 capture. Our findings provide valuable insight for the design of next-generation materials containing oxygen-based nucleophiles for carbon capture applications.", "year": 2025, "publicationDate": "2025-07-10", "publicationTypes": ["JournalArticle"], "venue": "Journal of the American Chemical Society", "journal": {"name": "Journal of the American Chemical Society"}, "citationCount": 11, "referenceCount": 54, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2305052975", "name": "S. A. Lim"}, {"authorId": "1416580239", "name": "Mary E. Zick"}, {"authorId": "2248036370", "name": "Jaehwan Kim"}, {"authorId": "2064456229", "name": "B. J. Rhodes"}, {"authorId": "93822588", "name": "Joharimanitra Randrianandraina"}, {"authorId": "112921307", "name": "Tristan A. Pitt"}, {"authorId": "2067315829", "name": "Ronald T Jerozal"}, {"authorId": "2247914895", "name": "Jung-Hoon Lee"}, {"authorId": "6883861", "name": "Alexander C. Forse"}, {"authorId": "5687407", "name": "P. Milner"}], "url": "https://www.semanticscholar.org/paper/e5dae63bdd8f0f337f3bdcd9985a53cb88c5c665", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "6f3a0e38aef3873980c1d0beafbe33edc92d6f93", "title": "Neo-Carbon Food concept: A pilot-scale hybrid biological–inorganic system with direct air capture of carbon dioxide", "abstract": "Abstract The pace at which the human population is growing raises serious concerns related to food security while at the same time conventional agriculture-based food production is becoming a major cause of environmental pollution and greenhouse gas emissions. Numerous solutions have been proposed to boost food production among which edible microbial biomass is considered a promising alternative to conventional sources of food and feed with lower environmental footprint. This work introduces the Neo-Carbon Food concept that is a pilot-scale hybrid biological–inorganic process suitable for the production of microbial biomass. The concept includes integrated hydrogen production by water electrolysis, direct air capture (DAC) of carbon dioxide, and its subsequent assimilation by autotrophic hydrogen-oxidizing bacteria (HOB). The hydrogen production with in situ electrolysis achieved specific energy consumption just below 100 kWh/kgH2 while the specific energy consumption of DAC was around 20 kWh/kgCO2.", "year": 2021, "publicationDate": null, "publicationTypes": [], "venue": null, "journal": {"name": "Journal of Cleaner Production", "pages": "123423", "volume": "278"}, "citationCount": 30, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.jclepro.2020.123423", "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "3107750", "name": "V. Ruuskanen"}, {"authorId": "96884823", "name": "Georgy Givirovskiy"}, {"authorId": "90858417", "name": "Jere Elfving"}, {"authorId": "100733094", "name": "Petteri Kokkonen"}, {"authorId": "103032659", "name": "A. Karvinen"}, {"authorId": "21158867", "name": "Lauri Järvinen"}, {"authorId": "94720567", "name": "J. Sillman"}, {"authorId": "2003535963", "name": "M. Vainikka"}, {"authorId": "34264909", "name": "J. Ahola"}], "url": "https://www.semanticscholar.org/paper/6f3a0e38aef3873980c1d0beafbe33edc92d6f93", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "7dac5d54ac8d44b4b007a9a32492f16d67690e99", "title": "Cost Analysis of Direct Air Capture and Sequestration Coupled to Low-Carbon Thermal Energy in the U.S.", "abstract": "Negative emissions technologies will play an important role in preventing 2°C warming by 2100. The next decade is critical for technological innovation and deployment to meet mid-century carbon removal goals of 10 - 20 GtCO2 /yr. Direct air capture (DAC) is positioned to play a critical role in carbon removal, yet remains under paced in deployment efforts, mainly due to high costs. This study outlines a roadmap for DAC cost reductions through the exploitation of low-temperature heat, recent US policy drivers, and logical, regional end-use opportunities in the US. Specifically, two scenarios are identified that allow for the production of compressed high-purity CO2 for costs  $300/tCO2, net delivered with an opportunity to scale to 19 MtCO2/yr. These scenarios use thermal energy from geothermal and nuclear power plants to produce steam and transport the purified CO2 via trucks to the nearest opportunity for direct use or subsurface permanent storage. While some utilization pathways result in the re-emission of CO2 and cannot be considered true carbon removal, they would provide economic incentive to deploying DAC plants at scale by mid-century. In addition, the federal tax credit 45Q was applied for qualifying facilities, (i.e., producing  100 ktCO2/yr).", "year": 2020, "publicationDate": "2020-05-15", "publicationTypes": ["JournalArticle"], "venue": "Environmental Science and Technology", "journal": {"name": "Environmental science & technology"}, "citationCount": 161, "referenceCount": 50, "influentialCitationCount": 3, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Environmental Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "1572251171", "name": "N. McQueen"}, {"authorId": "13143608", "name": "P. Psarras"}, {"authorId": "117307548", "name": "H. Pilorgé"}, {"authorId": "46763215", "name": "S. Liguori"}, {"authorId": "47752169", "name": "Jiajun He"}, {"authorId": "47548819", "name": "Mengyao Yuan"}, {"authorId": "40100405", "name": "Caleb M. Woodall"}, {"authorId": "92235449", "name": "Kourosh Kian"}, {"authorId": "96402572", "name": "L. Pierpoint"}, {"authorId": "93154362", "name": "J. Jurewicz"}, {"authorId": "2052981966", "name": "J. M. Lucas"}, {"authorId": "153611693", "name": "Rory Jacobson"}, {"authorId": "120288301", "name": "Noah Deich"}, {"authorId": "145008880", "name": "J. Wilcox"}], "url": "https://www.semanticscholar.org/paper/7dac5d54ac8d44b4b007a9a32492f16d67690e99", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "955877f4955dd4211d99c5646d59f517aad81788", "title": "Carbon Purchase Agreements, Dactories, and Supply-Chain Innovation: What Will It Take to Scale-Up Modular Direct Air Capture Technology to a Gigatonne Scale", "abstract": "Natural and engineered carbon dioxide removal have become regular features of climate models which limit warming to 1.5°C or even 2°C above pre-industrial levels. This gives rise to an assumption that solutions, for example direct air capture (DAC)—involving the direct removal of carbon dioxide from ambient air—can be commercialised and deployed at the necessary speed and scale to have a material impact, in the order of gigatonnes, by mid-century. Modular, solid-sorbent DAC on a gigatonne scale will require the mass mobilisation of supply chains to manufacture millions of modular DAC units−20 million of the present state of the art 50 tonne/year modules to deliver 1 gigatonne per year, as well as the large-scale production of novel chemical sorbents. To achieve a climate relevant DAC industry will demand innovative procurement models, for example carbon purchase agreements (CPAs), and dedicated DAC manufacturing facilities or dactories. In addition, insight is offered through the work of DAC start-up Carbon Infinity into the industry supply-chain position, adopting lessons from computing, and energy technologies. In particular, we look at approaches to drive demand and scale-up DAC module production, and opportunities presented in the development of an integrated DAC manufacturing industry.", "year": 2021, "publicationDate": "2021-04-07", "publicationTypes": [], "venue": "Frontiers in Climate", "journal": {"volume": "3"}, "citationCount": 17, "referenceCount": 43, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fclim.2021.636657/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Business", "source": "s2-fos-model"}], "authors": [{"authorId": "2282178917", "name": "David Izikowitz"}], "url": "https://www.semanticscholar.org/paper/955877f4955dd4211d99c5646d59f517aad81788", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "779b2ba2830a15d4e5f5749da6916c93578d0728", "title": "Membrane Separation Technology in Direct Air Capture", "abstract": "Direct air capture (DAC) is an emerging negative CO2 emission technology that aims to introduce a feasible method for CO2 capture from the atmosphere. Unlike carbon capture from point sources, which deals with flue gas at high CO2 concentrations, carbon capture directly from the atmosphere has proved difficult due to the low CO2 concentration in ambient air. Current DAC technologies mainly consider sorbent-based systems; however, membrane technology can be considered a promising DAC approach since it provides several advantages, e.g., lower energy and operational costs, less environmental footprint, and more potential for small-scale ubiquitous installations. Several recent advancements in validating the feasibility of highly permeable gas separation membrane fabrication and system design show that membrane-based direct air capture (m-DAC) could be a complementary approach to sorbent-based DAC, e.g., as part of a hybrid system design that incorporates other DAC technologies (e.g., solvent or sorbent-based DAC). In this article, the ongoing research and DAC application attempts via membrane separation have been reviewed. The reported membrane materials that could potentially be used for m-DAC are summarized. In addition, the future direction of m-DAC development is discussed, which could provide perspective and encourage new researchers’ further work in the field of m-DAC.", "year": 2024, "publicationDate": "2024-01-24", "publicationTypes": ["Review", "JournalArticle"], "venue": "Membranes", "journal": {"name": "Membranes", "volume": "14"}, "citationCount": 37, "referenceCount": 178, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2077-0375/14/2/30/pdf?version=1706089149", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2281225617", "name": "Pavlo Ignatusha"}, {"authorId": "4853864", "name": "Haiqing Lin"}, {"authorId": "2281219867", "name": "Noé Kapuscinsky"}, {"authorId": "11937047", "name": "L. Scoles"}, {"authorId": "2267016046", "name": "Weiguo Ma"}, {"authorId": "92041320", "name": "B. Patarachao"}, {"authorId": "2281135838", "name": "Naiying Du"}], "url": "https://www.semanticscholar.org/paper/779b2ba2830a15d4e5f5749da6916c93578d0728", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "2c09fda753f031ec737ae9f1140c2f12ad5dce24", "title": "Solar-Powered Direct Air Capture: Techno-Economic and Environmental Assessment", "abstract": "Direct air capture (DAC) of CO2 has gained attention as a sustainable carbon source. One of the most promising technologies currently available is liquid solvent DAC (L-DAC), but the significant fraction of fossil CO2 in the output stream hinders its utilization in carbon-neutral fuels and chemicals. Fossil CO2 is generated and captured during the combustion of fuels to calcine carbonates, which is difficult to decarbonize due to the high temperatures required. Solar thermal energy can provide green high-temperature heat, but it flourishes in arid regions where environmental conditions are typically unfavorable for L-DAC. This study proposes a solar-powered L-DAC approach and develops a model to assess the influence of the location and plant capacity on capture costs. The performed life cycle assessment enables the comparison of technologies based on net CO2 removal, demonstrating that solar-powered L-DAC is not only more environmentally friendly but also more cost-effective than conventional L-DAC.", "year": 2024, "publicationDate": "2024-01-25", "publicationTypes": ["JournalArticle"], "venue": "Environmental Science and Technology", "journal": {"name": "Environmental Science & Technology", "pages": "2282 - 2292", "volume": "58"}, "citationCount": 37, "referenceCount": 56, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.acs.org/doi/pdf/10.1021/acs.est.3c08269", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2132584798", "name": "Enric Prats-Salvado"}, {"authorId": "2399060732", "name": "N. Jagtap"}, {"authorId": "21265725", "name": "N. Monnerie"}, {"authorId": "2274783732", "name": "Christian Sattler"}], "url": "https://www.semanticscholar.org/paper/2c09fda753f031ec737ae9f1140c2f12ad5dce24", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "6a745a35c03dd71d78d4d1613af8f0da74a931ca", "title": "How Low-Carbon Heat Requirements for Direct Air Capture of CO2 Can Enable the Expansion of Firm Low-Carbon Electricity Generation Resources", "abstract": "A rapid build-out of direct air capture (DAC), deployed in order to mitigate climate change, will require significant amounts of both low-carbon thermal and electrical energy. Firm low-carbon power resources, including nuclear, geothermal, or natural gas with carbon capture, which also will become more highly valued as variable renewable energy penetration increases, would be able to provide both heat and electricity for DAC. In this study, we examined the techno-economic synergy between a hypothetical DAC plant in the year 2030 and a nuclear small modular reactor, and determined two avenues for which this relationship could benefit the nuclear plant. First, we demonstrated that, under certain assumptions, selling a portion of its energy to a DAC facility allows the nuclear plant to take in 21% less revenue from selling electricity to wholesale markets than its projected levelized cost, and still break even. Second, after estimating a potential revenue stream, we showed that an integration with DAC allows for the nuclear plant's capital costs to be up to 35% higher than what would be required if only selling electricity to wholesale markets. This could enable the nuclear plant to operate economically even in the face of variable and decreasing wholesale electricity prices, and also could offer developers more financial certainty when planning a new project. Ultimately, this study shows that the need for low-carbon energy for DAC plants might incentivize the development of advanced nuclear plants and firm low-carbon resources more broadly.", "year": 2021, "publicationDate": "2021-09-07", "publicationTypes": [], "venue": "Frontiers in Climate", "journal": {"volume": "3"}, "citationCount": 16, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fclim.2021.728719/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2047284150", "name": "Daniel Slesinski"}, {"authorId": "41185706", "name": "Scott J. Litzelman"}], "url": "https://www.semanticscholar.org/paper/6a745a35c03dd71d78d4d1613af8f0da74a931ca", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "cd759fa1911b67598823faa80e9f7e9f420472e0", "title": "Polymer Sorbent Design for the Direct Air Capture of CO2", "abstract": "Anthropogenic activities have resulted in enormous increases in atmospheric CO2 concentrations particularly since the onset of the Industrial Revolution, which have potential links with increased global temperatures, rising sea levels, increased prevalence, and severity of natural disasters, among other consequences. To enable a carbon-neutral and sustainable society, various technologies have been developed for CO2 capture from industrial process streams as well as directly from air. Here, direct air capture (DAC) represents an essential need for reducing CO2 concentration in the atmosphere to mitigate the negative consequences of greenhouse effects, involving systems that can reversibly adsorb and release CO2, in which polymers have played an integral role. This work provides insights into the development of polymer sorbents for DAC of CO2, specifically from the perspective of material design principles. We discuss how physical properties and chemical identities of amine-containing polymers can impact their ability to uptake CO2, as well as be efficiently regenerated. Additionally, polymers which use ionic interactions to react with CO2 molecules, such as poly(ionic liquids), are also common DAC sorbent materials. Finally, a perspective is provided on the future research and technology opportunities of developing polymer-derived sorbents for DAC.", "year": 2024, "publicationDate": "2024-03-30", "publicationTypes": ["Review", "JournalArticle"], "venue": "ACS Applied Polymer Materials", "journal": {"name": "ACS Applied Polymer Materials", "pages": "14169 - 14189", "volume": "6"}, "citationCount": 32, "referenceCount": 165, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.acs.org/doi/pdf/10.1021/acsapm.3c03199", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "144214720", "name": "M. Robertson"}, {"authorId": "2265353840", "name": "Jin Qian"}, {"authorId": "2291777905", "name": "Zhe Qiang"}], "url": "https://www.semanticscholar.org/paper/cd759fa1911b67598823faa80e9f7e9f420472e0", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "ef24c1460d9a0983d51120c4980f046725b53456", "title": "Assessing Impacts of Atmospheric Conditions on Efficiency and Siting of Large-Scale Direct Air Capture Facilities", "abstract": "The cost and efficiency of direct air capture (DAC) of carbon dioxide (CO2) will be decisive in determining whether this technology can play a large role in decarbonization. To probe the role of meteorological conditions on DAC we examine, at 1 × 1° resolution for the continental United States (U.S.), the impacts of temperature, humidity, atmospheric pressure, and CO2 concentration for a representative amine-based adsorption process. Spatial and temporal variations in atmospheric pressure and CO2 concentration lead to strong variations in the CO2 available in ambient air across the U.S. The specific DAC process that we examine is described by a process model that accounts for both temperature and humidity. A process that assumes the same operating choices at all locations in the continental U.S. shows strong variations in performance, with the most influential variables being the H2O gas phase volume fraction and temperature, both of which are negatively correlated with DAC productivity for the specific process that we consider. The process also shows a moderate positive correlation of ambient CO2 with productivity and recovery. We show that optimizing the DAC process at seven representative locations to reflect temporal and spatial variations in ambient conditions significantly improves the process performance and, more importantly, would lead to different choices in the sites for the best performance than models based on a single set of process conditions. Our work provides a framework for assessing spatial variations in DAC performance that could be applied to any DAC process and indicates that these variations will have important implications in optimizing and siting DAC facilities.", "year": 2024, "publicationDate": "2024-05-01", "publicationTypes": ["JournalArticle"], "venue": "JACS Au", "journal": {"name": "JACS Au", "pages": "1883 - 1891", "volume": "4"}, "citationCount": 29, "referenceCount": 40, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.acs.org/doi/pdf/10.1021/jacsau.4c00082", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "96522287", "name": "Xuqing Cai"}, {"authorId": "2212484980", "name": "Mark Coletti"}, {"authorId": "2061805", "name": "D. Sholl"}, {"authorId": "2395777520", "name": "Melissa R. Allen-Dumas"}], "url": "https://www.semanticscholar.org/paper/ef24c1460d9a0983d51120c4980f046725b53456", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "7d0a6885b8e20900bb89f8eeebc88288919ff0bd", "title": "Assessment of the Potential of Electrochemical Steps in Direct Air Capture through Techno-Economic Analysis", "abstract": "Direct air capture (DAC) technologies are proposed to reduce the atmospheric CO2 concentration to mitigate climate change and simultaneously provide carbon as a feedstock independent of fossil resources. The currently high energy demand and cost of DAC technologies are challenging and could limit the significance of DAC processes. The present work estimates the potential energy demand and the levelized cost of capture (LCOC) of liquid solvent absorption and solid adsorption DAC processes in the long term. A consistent framework is applied to compare nonelectrochemical to electrochemical DAC processes and estimate the LCOC depending on the electricity price. We determine the equivalent cell voltage needed for the electrochemical steps to achieve comparable or lower energy demand than nonelectrochemical processes. The capital expenses (CapEx) of the electrochemical steps are estimated using analogies to processes that are similar in function. The results are calculated for a range of initial data of CapEx and energy demand to include uncertainties in the data.", "year": 2024, "publicationDate": "2024-08-05", "publicationTypes": ["JournalArticle"], "venue": "Energy & Fuels", "journal": {"name": "Energy & Fuels", "pages": "15469 - 15481", "volume": "38"}, "citationCount": 22, "referenceCount": 74, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.acs.org/doi/pdf/10.1021/acs.energyfuels.4c02202", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2315215370", "name": "Natalie Rosen"}, {"authorId": "145915066", "name": "Andreas Welter"}, {"authorId": "2315212437", "name": "Martin Schwankl"}, {"authorId": "5865849", "name": "N. Plumeré"}, {"authorId": "2076505574", "name": "Júnior Staudt"}, {"authorId": "2263507060", "name": "Jakob Burger"}], "url": "https://www.semanticscholar.org/paper/7d0a6885b8e20900bb89f8eeebc88288919ff0bd", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "fd44b759059b6a7ce392c8410732fcfb3f9af623", "title": "Integrating direct air capture with small modular nuclear reactors: understanding performance, cost, and potential", "abstract": "Direct air capture (DAC) is a key component in the transition to net-zero society. However, its giga-tonne deployment faces daunting challenges in terms of availability of both financial resources and, most of all, large quantities of low-carbon energy. Within this context, small modular nuclear reactors (SMRs) might potentially facilitate the deployment of DAC. In the present study, we present a detailed thermodynamic analysis of integrating an SMR with solid sorbent DAC. We propose different integration designs and find that coupling the SMR with DAC significantly increases the use of thermal energy produced in the nuclear reactor: from 32% in a stand-alone SMR to 76%–85% in the SMR-DAC system. Moreover, we find that a 50–MW SMR module equipped with DAC could remove around 0.3 MtCO2 every year, while still producing electricity at 24%–42% of the rated power output. Performing a techno-economic analysis of the system, we estimate a net removal cost of around 250 €/tCO2. When benchmarking it to other low-carbon energy supply solutions, we find that the SMR-DAC system is potentially more cost-effective than a DAC powered by high-temperature heat pumps or dedicated geothermal systems. Finally, we evaluate the potential of future deployment of SMR-DAC in China, Europe, India, South Africa and the USA, finding that it could enable up to around 96 MtCO2/year by 2035 if SMRs prove to be cost-competitive. The impact of regional differences on the removal cost is also assessed.", "year": 2024, "publicationDate": "2024-01-29", "publicationTypes": ["JournalArticle"], "venue": "Journal of Physics: Energy", "journal": {"name": "Journal of Physics: Energy", "volume": "6"}, "citationCount": 22, "referenceCount": 33, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://iopscience.iop.org/article/10.1088/2515-7655/ad2374/pdf", "fieldsOfStudy": ["Physics"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2282042133", "name": "Luca Bertoni"}, {"authorId": "92427693", "name": "Simon Roussanaly"}, {"authorId": "2282042555", "name": "Luca Riboldi"}, {"authorId": "40629990", "name": "R. Anantharaman"}, {"authorId": "13501409", "name": "M. Gazzani"}], "url": "https://www.semanticscholar.org/paper/fd44b759059b6a7ce392c8410732fcfb3f9af623", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "0bcae2dc1ae2849e8b3b8a9fb630968e173d42a4", "title": "Probing Structural Transformations and Degradation Mechanisms by Direct Observation in SIFSIX-3-Ni for Direct Air Capture.", "abstract": "Despite global efforts to reduce carbon dioxide (CO2) emissions, continued industrialization threatens to exacerbate climate change. This work investigates methods to capture CO2, with a focus on the SIFSIX-3-Ni metal-organic framework (MOF) as a direct air capture (DAC) sorbent. SIFSIX-3-Ni exhibits promising CO2 adsorption properties but suffers from degradation processes under accelerated aging, which are akin to column regeneration conditions. Herein, we have grown the largest SIFSIX-3-Ni single crystals to date, facilitating single crystal X-ray diffraction analyses that enabled direct observation of the H2O and CO2 dynamics through adsorption and desorption. In addition, a novel space group (I4/mcm) for the SIFSIX-3-Ni is identified, which provided insights into structural transitions within the framework and elucidated water's role in degrading CO2 uptake performance as the material ages. In situ X-ray scattering methods revealed long-range and local structural transformations associated with CO2 adsorption in the framework pores as well as a temperature-dependent desorption mechanism. Pair distribution function analysis revealed a partial decomposition to form nonporous single-layer nanosheets of edge-sharing nickel oxide octahedra upon aging. The formation of these nanosheets is irreversible and reduces the amount of active material for the CO2 sorption. These findings provide crucial insights for the development of efficient and stable DAC sorbents, effectively reducing greenhouse gases, and suggest avenues for enhancing MOF stability under practical DAC conditions.", "year": 2024, "publicationDate": "2024-01-25", "publicationTypes": ["JournalArticle"], "venue": "Journal of the American Chemical Society", "journal": {"name": "Journal of the American Chemical Society"}, "citationCount": 20, "referenceCount": 34, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "118529723", "name": "Michael L. Barsoum"}, {"authorId": "2281322096", "name": "Jan Hofmann"}, {"authorId": "15249840", "name": "Haomiao Xie"}, {"authorId": "95633471", "name": "Zhihengyu Chen"}, {"authorId": "19168066", "name": "Simon M. Vornholt"}, {"authorId": "46710321", "name": "Roberto dos Reis"}, {"authorId": "2212784392", "name": "Nicholas Burns"}, {"authorId": "2238150761", "name": "Stefan W. Kycia"}, {"authorId": "6901045", "name": "K. Chapman"}, {"authorId": "5207880", "name": "V. Dravid"}, {"authorId": "5385033", "name": "O. Farha"}], "url": "https://www.semanticscholar.org/paper/0bcae2dc1ae2849e8b3b8a9fb630968e173d42a4", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "7a89db78ae5096be54df544b19e8ecbbf043e5b6", "title": "Carbon dioxide direct air capture for effective climate change mitigation based on renewable electricity: a new type of energy system sector coupling", "abstract": "Pathways for achieving the 1.5–2 °C global temperature moderation target imply a massive scaling of carbon dioxide (CO 2 ) removal technologies, in particular in the 2040s and onwards. CO 2 direct air capture (DAC) is among the most promising negative emission technologies (NETs). The energy demands for low-temperature solid-sorbent DAC are mainly heat at around 100 °C and electricity, which lead to sustainably operated DAC systems based on low-cost renewable electricity and heat pumps for the heat supply. This analysis is carried out for the case of the Maghreb region, which enjoys abundantly available low-cost renewable energy resources. The energy transition results for the Maghreb region lead to a solar photovoltaic (PV)-dominated energy supply with some wind energy contribution. DAC systems will need the same energy supply structure. The research investigates the levelised cost of CO 2 DAC (LCOD) in high spatial resolution and is based on full hourly modelling for the Maghreb region. The key results are LCOD of about 55 €/t CO2 in 2050 with a further cost reduction potential of up to 50%. The area demand is considered and concluded to be negligible. Major conclusions for CO 2 removal as a new energy sector are drawn. Key options for a global climate change mitigation strategy are first an energy transition towards renewable energy and second NETs for achieving the targets of the Paris Agreement.", "year": 2019, "publicationDate": "2019-02-13", "publicationTypes": [], "venue": "Mitigation and Adaptation Strategies for Global Change", "journal": {"name": "Mitigation and Adaptation Strategies for Global Change", "pages": "43-65", "volume": "25"}, "citationCount": 148, "referenceCount": 50, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s11027-019-9847-y.pdf", "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "9376135", "name": "C. Breyer"}, {"authorId": "51169074", "name": "M. Fasihi"}, {"authorId": "30637601", "name": "A. Aghahosseini"}], "url": "https://www.semanticscholar.org/paper/7a89db78ae5096be54df544b19e8ecbbf043e5b6", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "d150e9b818afa117a00fb5bb80755fa2d2c73bdd", "title": "Life cycle carbon efficiency of Direct Air Capture systems with strong hydroxide sorbents", "abstract": "Abstract Direct Air Capture (DAC) of carbon dioxide (CO2) from ambient air has the potential to combat climate change. DAC systems capture CO2 using a sorbent material and compress it for storage. In this study, we calculated the life cycle carbon efficiency (Ec) of a DAC system which equals the net amount of carbon stored per amount of carbon captured from capture to geological storage. We included greenhouse gas (GHG) emissions during construction of the necessary facilities as well as GHG emissions from energy, water and chemicals needed during operations. The system we analysed includes a hydroxide solution as sorbent material and utilizes the pelletized variant of the Kraft process to regenerate the sorbent and separate the CO2. To our knowledge, the potential climate benefit over the full life cycle of this DAC system has not been fully investigated up to now. Using the baseline scenario, we obtained a positive Ec of 62%. For the optimistic and pessimistic scenarios, we found a Ec of 93% and 10%, respectively. We conclude that this type of DAC system may be a feasible option to help keep limit global temperature increases to well below 2 °C.", "year": 2019, "publicationDate": null, "publicationTypes": [], "venue": "International Journal of Greenhouse Gas Control", "journal": {"name": "International Journal of Greenhouse Gas Control"}, "citationCount": 115, "referenceCount": 38, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://repository.ubn.ru.nl//bitstream/handle/2066/199575/199575pre.pdf", "fieldsOfStudy": ["Environmental Science"], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "1400669641", "name": "Melinda M J de Jonge"}, {"authorId": "2061658911", "name": "J. Daemen"}, {"authorId": "96986935", "name": "J. Loriaux"}, {"authorId": "14921481", "name": "Zoran J. N. Steinmann"}, {"authorId": "4335045", "name": "M. Huijbregts"}], "url": "https://www.semanticscholar.org/paper/d150e9b818afa117a00fb5bb80755fa2d2c73bdd", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "8c725c9be811f5a7a9a49505bdbee3886a4cd721", "title": "Facile Synthesis of Self-supported Solid Amine Sorbents for Direct Air Capture.", "abstract": "Conventional usage of tetraethylenepentamine (TEPA) via being supported on porous solid materials for carbon capture is susceptible to oxidative degradation during regeneration cycles. This study reports a novel method to synthesize a TEPA based solid polymer for efficient CO2 removal via direct air capture (DAC). The polymer was obtained through epoxy-amine crosslinking reaction, leading to the transformation of liquid TEPA to a self-supported solid polymer. The synthesis was conducted under ambient conditions via a one-pot process with no waste products, which is aligned with green synthesis. The performance of the solid amine was evaluated in DAC under realistic conditions and compared with TEPA supported on SiO2 and zeolite 13X prepared through the conventional method. The solid TEPA amine exhibited a high CO2 uptake of 6.2 wt.% comparable to the conventional counterparts. More importantly, the solid TEPA amine demonstrated high resistance to oxidation during the accelerated ageing process at 80 °C in air for 24 h, whereas the two supported TEPA samples experienced severe degradation, with zeolite 13X supported TEPA incurring a reduction of 86.5% in CO2 capturing capacity after the ageing. This work sheds light on the novel usage of TEPA as an efficient solid amine for practical DAC operation.", "year": 2024, "publicationDate": "2024-04-25", "publicationTypes": ["JournalArticle"], "venue": "ChemSusChem", "journal": {"name": "ChemSusChem", "pages": "\n          e202400212\n        "}, "citationCount": 16, "referenceCount": 0, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cssc.202400212", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2274413313", "name": "Zhijian Wan"}, {"authorId": "2280405469", "name": "Russell Hunt"}, {"authorId": "2281024739", "name": "Cameron White"}, {"authorId": "2265554235", "name": "Jeremy Gillbanks"}, {"authorId": "2280391576", "name": "Jason Czapla"}, {"authorId": "14296549", "name": "Gongkui Xiao"}, {"authorId": "2298228881", "name": "Sophia Surin"}, {"authorId": "2280411109", "name": "C. Wood"}], "url": "https://www.semanticscholar.org/paper/8c725c9be811f5a7a9a49505bdbee3886a4cd721", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "ad2190e7a36b20d5bdddba3dfe395d2953a4296a", "title": "Scalable and Highly Porous Membrane Adsorbents for Direct Air Capture of CO2.", "abstract": "Direct air capture (DAC) of CO2 is a carbon-negative technology to mitigate carbon emissions, and it requires low-cost sorbents with high CO2 sorption capacity that can be easily manufactured on a large scale. In this work, we develop highly porous membrane adsorbents comprising branched polyethylenimine (PEI) impregnated in low-cost, porous Solupor supports. The effect of the PEI molecular mass and loading on the physical properties of the adsorbents is evaluated, including porosity, degradation temperature, glass transition temperature, and CO2 permeance. CO2 capture from simulated air containing 400 ppm of CO2 in these sorbents is thoroughly investigated as a function of temperature and relative humidity (RH). Polymer dynamics was examined using differential scanning calorimetry (DSC) and broadband dielectric spectroscopy (BDS), showing that CO2 sorption is limited by its diffusion in these PEI-based sorbents. A membrane adsorbent containing 48 mass% PEI (800 Da) with a porosity of 72% exhibits a CO2 sorption capacity of 1.2 mmol/g at 25 °C and RH of 30%, comparable to the state-of-the-art adsorbents. Multicycles of sorption and desorption were performed to determine their regenerability, stability, and potential for practical applications.", "year": 2024, "publicationDate": "2024-04-16", "publicationTypes": ["JournalArticle"], "venue": "ACS Applied Materials and Interfaces", "journal": {"name": "ACS applied materials & interfaces"}, "citationCount": 17, "referenceCount": 37, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "46602595", "name": "Thien N. Tran"}, {"authorId": "2267025041", "name": "Shweta Singh"}, {"authorId": "2273315212", "name": "Shiwang Cheng"}, {"authorId": "4853864", "name": "Haiqing Lin"}], "url": "https://www.semanticscholar.org/paper/ad2190e7a36b20d5bdddba3dfe395d2953a4296a", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "4a663dcf2f753bb14694969a0cfa7978ed35166b", "title": "The performance of solvent-based direct air capture across geospatial and temporal climate regimes", "abstract": "Liquid-solvent direct air capture (DAC) is a prominent approach for carbon dioxide removal but knowing where to site these systems is challenging because it requires considering a multitude of interrelated geospatial factors. Two of the most pressing factors are: (1) how should DAC be powered to provide the greatest net removal of CO2 and (2) how does weather impact its performance?.To investigate these questions, this study develops a process-level model of a liquid-solvent DAC system and couples it to a 20-year dataset of temperature and humidity conditions at a ~9km resolution across the contiguous US.We find that the amount of CO2 sequestered could be 30% to 50% greater than the amount of CO2 removed from the atmosphere if natural gas is burned on site to power DAC, but that the optimal way to power DAC is independent of capture rate (i.e., weather), depending solely on the upstream GHG intensity of electricity and natural gas. Regardless of how it is powered, air temperature and humidity conditions can change the performance of DAC by up to ~3x and can also vary substantially across weather years. Across the continuous US, we find that southern states (e.g., Gulf Coast) are preferrable locations for a variety of reasons, including higher and less variable air temperature and relative humidity. Lastly, we also find the performance of liquid-solvent DAC calculated with monthly means is within 2% of the estimated performance calculated with hourly data for more than a third of the country, including in the states with weather most favorable for liquid-solvent DAC.", "year": 2024, "publicationDate": "2024-04-29", "publicationTypes": ["JournalArticle"], "venue": "Frontiers in Climate", "journal": {"name": "Frontiers in Climate"}, "citationCount": 15, "referenceCount": 23, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/fclim.2024.1394728/pdf?isPublishedV2=False", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2299069279", "name": "Bjørn-Gustaf J. Brooks"}, {"authorId": "2299062158", "name": "Caleb H. Geissler"}, {"authorId": "2299070600", "name": "Keju An"}, {"authorId": "2299041437", "name": "Sean T. McCoy"}, {"authorId": "2266604482", "name": "R. S. Middleton"}, {"authorId": "1404071009", "name": "Jonathan D. Ogland-Hand"}], "url": "https://www.semanticscholar.org/paper/4a663dcf2f753bb14694969a0cfa7978ed35166b", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "cb83ff9be80fc926b56b09a31b8d4f49a1e3d4be", "title": "Physicochemical Properties, Equilibrium Adsorption Performance, Manufacturability, and Stability of TIFSIX-3-Ni for Direct Air Capture of CO2", "abstract": "The use of adsorbents for direct air capture (DAC) of CO2 is regarded as a promising and essential carbon dioxide removal technology to help meet the goals outlined by the 2015 Paris Agreement. A class of adsorbents that has gained significant attention for this application is ultramicroporous metal organic frameworks (MOFs). However, the necessary data needed to facilitate process scale evaluation of these materials is not currently available. Here, we investigate TIFSIX-3-Ni, a previously reported ultramicroporous MOF for DAC, and measure several physicochemical and equilibrium adsorption properties. We report its crystal structure, textural properties, thermal stability, specific heat capacity, CO2, N2, and H2O equilibrium adsorption isotherms at multiple temperatures, and Ar and O2 isotherms at a single temperature. For CO2, N2, and H2O, we also report isotherm model fitting parameters and calculate heats of adsorption. We assess the manufacturability and process stability of TIFSIX-3-Ni by investigating the impact of batch reproducibility, binderless pelletization, humidity, and adsorption–desorption cycling (50 cycles) on its crystal structure, textural properties, and CO2 adsorption. For pelletized TIFSIX-3-Ni, we also report its skeletal, pellet, and bed density, total pore volume, and pellet porosity. Overall, our data enable initial process modeling and optimization studies to evaluate TIFSIX-3-Ni for DAC at the process scale. They also highlight the possibility to pelletize TIFSIX-3-Ni and the limited stability of the MOF under humid and oxidative conditions as well as upon multiple adsorption–desorption cycles.", "year": 2024, "publicationDate": "2024-06-18", "publicationTypes": ["JournalArticle"], "venue": "Energy & Fuels", "journal": {"name": "Energy & Fuels", "pages": "11947 - 11965", "volume": "38"}, "citationCount": 15, "referenceCount": 49, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.acs.org/doi/pdf/10.1021/acs.energyfuels.4c01368", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "151501114", "name": "M. Low"}, {"authorId": "13797898", "name": "D. Danaci"}, {"authorId": "2132352969", "name": "Hassan Azzan"}, {"authorId": "2307381072", "name": "Amanda Lim Jiayi"}, {"authorId": "2307382620", "name": "Gordon Wu Shun Yong"}, {"authorId": "2165953689", "name": "Ioanna Itskou"}, {"authorId": "2238059903", "name": "Camille Petit"}], "url": "https://www.semanticscholar.org/paper/cb83ff9be80fc926b56b09a31b8d4f49a1e3d4be", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "847fbab17044d5e3bcef7f26faf3f7971915ff3a", "title": "Optimization of a combined power plant CO2 capture and direct air capture concept for flexible power plant operation", "abstract": "Deployment of carbon capture and storage (CCS) equipped fossil fuel power plants on the supply-side and direct air capture (DAC) technologies on the demand side can address the dual challenge...", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Energy &amp; Environmental Science", "journal": {"name": "Energy &amp; Environmental Science"}, "citationCount": 13, "referenceCount": 8, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.rsc.org/en/content/articlepdf/2024/ee/d4ee00309h", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2105864550", "name": "E. Graham"}, {"authorId": "51206568", "name": "Moataz N. Sheha"}, {"authorId": "3121882", "name": "D. Mallapragada"}, {"authorId": "46292745", "name": "H. Herzog"}, {"authorId": "6167860", "name": "E. Gençer"}, {"authorId": "115127152", "name": "P. Cross"}, {"authorId": "97019959", "name": "James Custer"}, {"authorId": "2221064442", "name": "Adam Goff"}, {"authorId": "46231433", "name": "I. Cormier"}], "url": "https://www.semanticscholar.org/paper/847fbab17044d5e3bcef7f26faf3f7971915ff3a", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "c6baa876f83506fdb3e9ddf040c2119046ae4f82", "title": "How Would Ideal Sorbents Improve the Technical and Economic Performance of Adsorption-Based Direct Air Capture?", "abstract": ": Current climate policies and national pledges are insufficient to achieve the necessary reduction in CO 2 emissions, underscoring the urgency of carbon dioxide removal (CDR) from the atmosphere. Direct air capture (DAC) is an engineered CDR process with substantial removal potential but also one with clear technical limits and opportunities for enhancement. One such improvement is the optimization of the material, enabling the separation. To investigate this from a quantitative perspective, this study evaluates DAC performance when replacing existing sorbents with theoretical ones designed to optimize the process. In order to do so, the adsorption isotherm parameters of CO 2 for different isotherm models were optimized along with process design variables to minimize energy and maximize productivity. Combining equilibrium and rate-based models, our analysis offers insights from thermodynamic, reactor, and economic perspectives. The results show that optimal sorbents have the potential to significantly improve the DAC performance obtained with existing sorbents, for example, Lewatit VP-OC-1065 and MIL-101, especially in terms of energy consumption and costs. This requires that some critical sorbent characteristics are met: moderate cost (e.g., <30$/kg), long lifetime (e.g., >2 years), and a linear driving force in line with other gas separation processes (e.g., k LDF > 0.001 s − 1 ). Furthermore, our findings highlight that optimizing productivity and energy consumption enables the identification of minimum-cost configurations for DAC. This work underscores the importance of tailored sorbent design in advancing DAC toward cost-effective, efficient CO 2 removal solutions.", "year": 2024, "publicationDate": "2024-09-12", "publicationTypes": ["JournalArticle"], "venue": "Energy &amp; Fuels", "journal": {"name": "Energy &amp; Fuels"}, "citationCount": 12, "referenceCount": 60, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1021/acs.energyfuels.4c01156", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "136858112", "name": "Alexa Grimm"}, {"authorId": "2248271899", "name": "Gert Jan Kramer"}, {"authorId": "2313837819", "name": "M. Gazzani"}], "url": "https://www.semanticscholar.org/paper/c6baa876f83506fdb3e9ddf040c2119046ae4f82", "_run_id": "oRB06ufKstry5CzsU", "_dataset_id": "fgfeS2Sr4bFGDmBac"}
{"paperId": "6801e48e38c1d49dac04a14ed076642a92c982ae", "title": "Combining LLM Code Generation with Formal Specifications and Reactive Program Synthesis", "abstract": "In the past few years, Large Language Models (LLMs) have exploded in usefulness and popularity for code generation tasks. However, LLMs still struggle with accuracy and are unsuitable for high-risk applications without additional oversight and verification. In particular, they perform poorly at generating code for highly complex systems, especially with unusual or out-of-sample logic. For such systems, verifying the code generated by the LLM may take longer than writing it by hand. We introduce a solution that divides the code generation into two parts; one to be handled by an LLM and one to be handled by formal methods-based program synthesis. We develop a benchmark to test our solution and show that our method allows the pipeline to solve problems previously intractable for LLM code generation.", "year": 2024, "publicationDate": "2024-09-18", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2410.19736"}, "citationCount": 11, "referenceCount": 19, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2305682966", "name": "William Murphy"}, {"authorId": "2305683996", "name": "Nikolaus Holzer"}, {"authorId": "2286875233", "name": "Feitong Qiao"}, {"authorId": "2306632017", "name": "Leyi Cui"}, {"authorId": "2260345250", "name": "Raven Rothkopf"}, {"authorId": "2305682772", "name": "Nathan Koenig"}, {"authorId": "2465596", "name": "Mark Santolucito"}], "url": "https://www.semanticscholar.org/paper/6801e48e38c1d49dac04a14ed076642a92c982ae", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "5bcb7c4aead89b324f38d8deb32978d82b7ed7f9", "title": "Unveiling the Power of Neural Program Synthesis in High Level Code Generation", "abstract": "In this research, we delve into a transformative exploration of the realm of code generation, unveiling three fundamental modules that constitute the backbone of our study: the Text-to-Code Generation Model, Code Autocompletion Model, and the formidable Neural Program Synthesis Model. At the forefront of our investigation, we underscore the paramount importance of Neural Program Synthesis—a dynamic force adept at crafting custom programs from input-output examples. Our exploration delves into the intricate landscape of natural language-to-code generation, offering profound insights and invaluable contributions to the field. The ability to automatically generate code from natural language instructions holds immense significance in streamlining software development processes, reducing manual effort, and enhancing productivity. Furthermore, this research addresses a pressing need within the software engineering community for efficient methods of code generation, particularly in domains where human-program interaction is prevalent. Through rigorous experimentation and meticulous analysis, we shed light on methodologies and promising avenues for future research in this burgeoning domain, paving the way for advancements in automated software development and programming assistance tools.", "year": 2024, "publicationDate": "2024-06-24", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Computing Communication and Networking Technologies", "journal": {"name": "2024 15th International Conference on Computing Communication and Networking Technologies (ICCCNT)", "pages": "1-8"}, "citationCount": 0, "referenceCount": 18, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2295765907", "name": "Gurram Kumar Sai"}, {"authorId": "2289071442", "name": "Koganti Sri"}, {"authorId": "2122687926", "name": "S. Harshith"}, {"authorId": "93515674", "name": "K. A. Varma"}, {"authorId": "2176582996", "name": "G. Kiran"}], "url": "https://www.semanticscholar.org/paper/5bcb7c4aead89b324f38d8deb32978d82b7ed7f9", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "b45ec1cb2ba6b2d1ac24723fa836aee06a3db97a", "title": "Is Your Code Generated by ChatGPT Really Correct? Rigorous Evaluation of Large Language Models for Code Generation", "abstract": "Program synthesis has been long studied with recent approaches focused on directly using the power of Large Language Models (LLMs) to generate code. Programming benchmarks, with curated synthesis problems and test-cases, are used to measure the performance of various LLMs on code synthesis. However, these test-cases can be limited in both quantity and quality for fully assessing the functional correctness of the generated code. Such limitation in the existing benchmarks begs the following question: In the era of LLMs, is the code generated really correct? To answer this, we propose EvalPlus -- a code synthesis evaluation framework to rigorously benchmark the functional correctness of LLM-synthesized code. EvalPlus augments a given evaluation dataset with large amounts of test-cases newly produced by an automatic test input generator, powered by both LLM- and mutation-based strategies. While EvalPlus is general, we extend the test-cases of the popular HumanEval benchmark by 80x to build HumanEval+. Our extensive evaluation across 26 popular LLMs (e.g., GPT-4 and ChatGPT) demonstrates that HumanEval+ is able to catch significant amounts of previously undetected wrong code synthesized by LLMs, reducing the pass@k by up-to 19.3-28.9%. We also surprisingly found that test insufficiency can lead to mis-ranking. For example, both WizardCoder-CodeLlama and Phind-CodeLlama now outperform ChatGPT on HumanEval+, while none of them could on HumanEval. Our work not only indicates that prior popular code synthesis evaluation results do not accurately reflect the true performance of LLMs for code synthesis, but also opens up a new direction to improve such programming benchmarks through automated testing. We have open-sourced our tools, enhanced datasets as well as all LLM-generated code at https://github.com/evalplus/evalplus to facilitate and accelerate future LLM-for-code research.", "year": 2023, "publicationDate": "2023-05-02", "publicationTypes": ["JournalArticle"], "venue": "Neural Information Processing Systems", "journal": {"name": "ArXiv", "volume": "abs/2305.01210"}, "citationCount": 2006, "referenceCount": 92, "influentialCitationCount": 194, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2124960443", "name": "Jiawei Liu"}, {"authorId": "145349987", "name": "Chun Xia"}, {"authorId": "2215893835", "name": "Yuyao Wang"}, {"authorId": "2145398332", "name": "Lingming Zhang"}], "url": "https://www.semanticscholar.org/paper/b45ec1cb2ba6b2d1ac24723fa836aee06a3db97a", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "e81c707040ce604c7102cfe14d78b72385c17b68", "title": "MapCoder: Multi-Agent Code Generation for Competitive Problem Solving", "abstract": "Code synthesis, which requires a deep understanding of complex natural language problem descriptions, generation of code instructions for complex algorithms and data structures, and the successful execution of comprehensive unit tests, presents a significant challenge. While large language models (LLMs) demonstrate impressive proficiency in natural language processing, their performance in code generation tasks remains limited. In this paper, we introduce a new approach to code generation tasks leveraging multi-agent prompting that uniquely replicates the full cycle of program synthesis as observed in human developers. Our framework, MapCoder, consists of four LLM agents specifically designed to emulate the stages of this cycle: recalling relevant examples, planning, code generation, and debugging. After conducting thorough experiments, with multiple LLM ablations and analyses across eight challenging competitive problem-solving and program synthesis benchmarks, MapCoder showcases remarkable code generation capabilities, achieving new state-of-the-art results (pass@1) on HumanEval (93.9%), MBPP (83.1%), APPS (22.0%), CodeContests (28.5%), and xCodeEval (45.3%). Moreover, our method consistently delivers superior performance across various programming languages and varying problem difficulties. We open-source our framework at https://github.com/Md-Ashraful-Pramanik/MapCoder.", "year": 2024, "publicationDate": "2024-05-18", "publicationTypes": ["JournalArticle", "Conference"], "venue": "Annual Meeting of the Association for Computational Linguistics", "journal": {"pages": "4912-4944"}, "citationCount": 258, "referenceCount": 48, "influentialCitationCount": 24, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2302455536", "name": "Md. Ashraful Islam"}, {"authorId": "2302578140", "name": "Mohammed Eunus Ali"}, {"authorId": "3405393", "name": "Md. Rizwan Parvez"}], "url": "https://www.semanticscholar.org/paper/e81c707040ce604c7102cfe14d78b72385c17b68", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "c5836fa8127fe158991486fd8f949c5c02cf0ed0", "title": "AutoSafeCoder: A Multi-Agent Framework for Securing LLM Code Generation through Static Analysis and Fuzz Testing", "abstract": "Recent advancements in automatic code generation using large language models (LLMs) have brought us closer to fully automated secure software development. However, existing approaches often rely on a single agent for code generation, which struggles to produce secure, vulnerability-free code. Traditional program synthesis with LLMs has primarily focused on functional correctness, often neglecting critical dynamic security implications that happen during runtime. To address these challenges, we propose AutoSafeCoder, a multi-agent framework that leverages LLM-driven agents for code generation, vulnerability analysis, and security enhancement through continuous collaboration. The framework consists of three agents: a Coding Agent responsible for code generation, a Static Analyzer Agent identifying vulnerabilities, and a Fuzzing Agent performing dynamic testing using a mutation-based fuzzing approach to detect runtime errors. Our contribution focuses on ensuring the safety of multi-agent code generation by integrating dynamic and static testing in an iterative process during code generation by LLM that improves security. Experiments using the SecurityEval dataset demonstrate a 13% reduction in code vulnerabilities compared to baseline LLMs, with no compromise in functionality.", "year": 2024, "publicationDate": "2024-09-16", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.10737"}, "citationCount": 51, "referenceCount": 28, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2321457019", "name": "Ana Nunez"}, {"authorId": "2215168083", "name": "Nafis Tanveer Islam"}, {"authorId": "39058278", "name": "S. Jha"}, {"authorId": "71756373", "name": "Peyman Najafirad"}], "url": "https://www.semanticscholar.org/paper/c5836fa8127fe158991486fd8f949c5c02cf0ed0", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "75bf5432ad95cd07b2d600b91d57cbcd4255befe", "title": "Guiding Enumerative Program Synthesis with Large Language Models", "abstract": "Pre-trained Large Language Models (LLMs) are beginning to dominate the discourse around automatic code generation with natural language specifications. In contrast, the best-performing synthesizers in the domain of formal synthesis with precise logical specifications are still based on enumerative algorithms. In this paper, we evaluate the abilities of LLMs to solve formal synthesis benchmarks by carefully crafting a library of prompts for the domain. When one-shot synthesis fails, we propose a novel enumerative synthesis algorithm, which integrates calls to an LLM into a weighted probabilistic search. This allows the synthesizer to provide the LLM with information about the progress of the enumerator, and the LLM to provide the enumerator with syntactic guidance in an iterative loop. We evaluate our techniques on benchmarks from the Syntax-Guided Synthesis (SyGuS) competition. We find that GPT-3.5 as a stand-alone tool for formal synthesis is easily outperformed by state-of-the-art formal synthesis algorithms, but our approach integrating the LLM into an enumerative synthesis algorithm shows significant performance gains over both the LLM and the enumerative synthesizer alone and the winning SyGuS competition tool.", "year": 2024, "publicationDate": "2024-03-06", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Computer Aided Verification", "journal": {"name": "ArXiv", "volume": "abs/2403.03997"}, "citationCount": 23, "referenceCount": 45, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2216969357", "name": "Yixuan Li"}, {"authorId": "25161908", "name": "Julian Parsert"}, {"authorId": "2346882258", "name": "Elizabeth Polgreen"}], "url": "https://www.semanticscholar.org/paper/75bf5432ad95cd07b2d600b91d57cbcd4255befe", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "a53c8ba374d430d6c3786d13c04edb200d547750", "title": "A Real-World WebAgent with Planning, Long Context Understanding, and Program Synthesis", "abstract": "Pre-trained large language models (LLMs) have recently achieved better generalization and sample efficiency in autonomous web automation. However, the performance on real-world websites has still suffered from (1) open domainness, (2) limited context length, and (3) lack of inductive bias on HTML. We introduce WebAgent, an LLM-driven agent that learns from self-experience to complete tasks on real websites following natural language instructions. WebAgent plans ahead by decomposing instructions into canonical sub-instructions, summarizes long HTML documents into task-relevant snippets, and acts on websites via Python programs generated from those. We design WebAgent with Flan-U-PaLM, for grounded code generation, and HTML-T5, new pre-trained LLMs for long HTML documents using local and global attention mechanisms and a mixture of long-span denoising objectives, for planning and summarization. We empirically demonstrate that our modular recipe improves the success on real websites by over 50%, and that HTML-T5 is the best model to solve various HTML understanding tasks; achieving 18.7% higher success rate than the prior method on MiniWoB web automation benchmark, and SoTA performance on Mind2Web, an offline task planning evaluation.", "year": 2023, "publicationDate": "2023-07-24", "publicationTypes": ["JournalArticle"], "venue": "International Conference on Learning Representations", "journal": {"name": "ArXiv", "volume": "abs/2307.12856"}, "citationCount": 394, "referenceCount": 100, "influentialCitationCount": 14, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2307.12856", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "3737312", "name": "Izzeddin Gur"}, {"authorId": "2052903664", "name": "Hiroki Furuta"}, {"authorId": "2054859790", "name": "Austin L. Huang"}, {"authorId": "2093894693", "name": "Mustafa Safdari"}, {"authorId": "2153732825", "name": "Yutaka Matsuo"}, {"authorId": "2396681", "name": "D. Eck"}, {"authorId": "145520045", "name": "Aleksandra Faust"}], "url": "https://www.semanticscholar.org/paper/a53c8ba374d430d6c3786d13c04edb200d547750", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "e48e1e69296a1df295a2fc2e4bb125ae048b5ba4", "title": "A Systematic Literature Review of 10 years of Research on Program Synthesis and Natural Language Processing", "abstract": null, "year": 2024, "publicationDate": "2024-12-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Programming and computer software", "journal": {"name": "Programming and Computer Software", "pages": "725 - 741", "volume": "50"}, "citationCount": 3, "referenceCount": 36, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1411786489", "name": "Rolando Ramírez-Rueda"}, {"authorId": "2281188949", "name": "E. Benítez-Guerrero"}, {"authorId": "1405639047", "name": "Carmen Mezura-Godoy"}, {"authorId": "144138367", "name": "E. Bárcenas"}], "url": "https://www.semanticscholar.org/paper/e48e1e69296a1df295a2fc2e4bb125ae048b5ba4", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "0a6bc37a07a37e3573d36e10cc11669eca0ff903", "title": "Execution-based Code Generation using Deep Reinforcement Learning", "abstract": "The utilization of programming language (PL) models, pre-trained on large-scale code corpora, as a means of automating software engineering processes has demonstrated considerable potential in streamlining various code generation tasks such as code completion, code translation, and program synthesis. However, current approaches mainly rely on supervised fine-tuning objectives borrowed from text generation, neglecting unique sequence-level characteristics of code, including but not limited to compilability as well as syntactic and functional correctness. To address this limitation, we propose PPOCoder, a new framework for code generation that synergistically combines pre-trained PL models with Proximal Policy Optimization (PPO) which is a widely used deep reinforcement learning technique. By utilizing non-differentiable feedback from code execution and structure alignment, PPOCoder seamlessly integrates external code-specific knowledge into the model optimization process. It's important to note that PPOCoder is a task-agnostic and model-agnostic framework that can be used across different code generation tasks and PLs. Extensive experiments on three code generation tasks demonstrate the effectiveness of our proposed approach compared to SOTA methods, achieving significant improvements in compilation success rates and functional correctness across different PLs.", "year": 2023, "publicationDate": "2023-01-31", "publicationTypes": ["JournalArticle"], "venue": "Trans. Mach. Learn. Res.", "journal": {"name": "ArXiv", "volume": "abs/2301.13816"}, "citationCount": 122, "referenceCount": 52, "influentialCitationCount": 11, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2301.13816", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2037848556", "name": "P. Shojaee"}, {"authorId": "2171130495", "name": "Aneesh Jain"}, {"authorId": "2121914227", "name": "Sindhu Tipirneni"}, {"authorId": "144417522", "name": "Chandan K. Reddy"}], "url": "https://www.semanticscholar.org/paper/0a6bc37a07a37e3573d36e10cc11669eca0ff903", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "439230dc63370fcece7771215ab794ceb7ad1c7a", "title": "E-code: Mastering Efficient Code Generation through Pretrained Models and Expert Encoder Group", "abstract": "Context: With the waning of Moore's Law, the software industry is placing increasing importance on finding alternative solutions for continuous performance enhancement. The significance and research results of software performance optimization have been on the rise in recent years, especially with the advancement propelled by Large Language Models(LLMs). However, traditional strategies for rectifying performance flaws have shown significant limitations at the competitive code efficiency optimization level, and research on this topic is surprisingly scarce. Objective: This study aims to address the research gap in this domain, offering practical solutions to the various challenges encountered. Specifically, we have overcome the constraints of traditional performance error rectification strategies and developed a Language Model (LM) tailored for the competitive code efficiency optimization realm. Method: We introduced E-code, an advanced program synthesis LM. Inspired by the recent success of expert LMs, we designed an innovative structure called the Expert Encoder Group. This structure employs multiple expert encoders to extract features tailored for different input types. We assessed the performance of E-code against other leading models on a competitive dataset and conducted in-depth ablation experiments. Results: Upon systematic evaluation, E-code achieved a 54.98% improvement in code efficiency, significantly outperforming other advanced models. In the ablation experiments, we further validated the significance of the expert encoder group and other components within E-code. Conclusion: The research findings indicate that the expert encoder group can effectively handle various inputs in efficiency optimization tasks, significantly enhancing the model's performance.", "year": 2024, "publicationDate": "2024-08-23", "publicationTypes": ["JournalArticle"], "venue": "Information and Software Technology", "journal": {"name": "Inf. Softw. Technol.", "pages": "107602", "volume": "178"}, "citationCount": 4, "referenceCount": 71, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2254907794", "name": "Yue Pan"}, {"authorId": "2316859995", "name": "Chen Lyu"}, {"authorId": "2316961155", "name": "Zhenyu Yang"}, {"authorId": "2316956969", "name": "Lantian Li"}, {"authorId": "2355253854", "name": "Qi Liu"}, {"authorId": "2316862033", "name": "Xiuting Shao"}], "url": "https://www.semanticscholar.org/paper/439230dc63370fcece7771215ab794ceb7ad1c7a", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "45849d17fe00b87fc4653d2bb65c95e38ed3b5fa", "title": "Neuro-Symbolic Program Synthesis for Multi-Hop Natural Language Navigation", "abstract": "Solving navigation problems from natural language descriptions is essential for advancing humanrobot interaction and enhancing the usability of autonomous systems. Symbolic approaches to path planning excel in well defined environments but cannot cope with the ambiguity of natural language inputs. On the other hand, neural solutions centered on large language models (LLMs) can parse free-form natural language but lack the reasoning capabilities for solving complex multihop path planning problems. In this paper, we propose a neuro-symbolic framework based on program synthesis for multi-hop natural language navigation called NSPS. The framework uses an LLM to parse the problem definition in natural language, a graph of the environment, and an API of a graph library. Next, the code generation capabilities of the LLM are used to synthesize a program for path planning and verification. The path planning program is executed to generate a solution path that is checked by the verification program. A selfcorrection loop is used to fix both syntax and value errors. The framework is evaluated using 600 multihop navigation tasks with 1 to 10 hops. Compared with neural approaches, the NSPS framework improves the success rate and path efficiency by an average of 64.3% and 19.4% across all tasks, respectively.", "year": 2024, "publicationDate": "2024-10-10", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Applied Algorithms", "journal": {"name": "2024 International Conference on Assured Autonomy (ICAA)", "pages": "114-117"}, "citationCount": 1, "referenceCount": 15, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2320721021", "name": "William English"}, {"authorId": "2276468421", "name": "Dominic Simon"}, {"authorId": "2319398955", "name": "Md Rubel Ahmed"}, {"authorId": "39058278", "name": "S. Jha"}, {"authorId": "2828546", "name": "Rickard Ewetz"}], "url": "https://www.semanticscholar.org/paper/45849d17fe00b87fc4653d2bb65c95e38ed3b5fa", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "afb8128b2c8016326131f5a12b657f2e9589a97f", "title": "Diffusion On Syntax Trees For Program Synthesis", "abstract": "Large language models generate code one token at a time. Their autoregressive generation process lacks the feedback of observing the program's output. Training LLMs to suggest edits directly can be challenging due to the scarcity of rich edit data. To address these problems, we propose neural diffusion models that operate on syntax trees of any context-free grammar. Similar to image diffusion models, our method also inverts ``noise'' applied to syntax trees. Rather than generating code sequentially, we iteratively edit it while preserving syntactic validity, which makes it easy to combine this neural model with search. We apply our approach to inverse graphics tasks, where our model learns to convert images into programs that produce those images. Combined with search, our model is able to write graphics programs, see the execution result, and debug them to meet the required specifications. We additionally show how our system can write graphics programs for hand-drawn sketches.", "year": 2024, "publicationDate": "2024-05-30", "publicationTypes": ["JournalArticle"], "venue": "International Conference on Learning Representations", "journal": {"name": "ArXiv", "volume": "abs/2405.20519"}, "citationCount": 11, "referenceCount": 42, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "40609354", "name": "Shreyas Kapur"}, {"authorId": "2287826196", "name": "Erik Jenner"}, {"authorId": "2304322887", "name": "Stuart Russell"}], "url": "https://www.semanticscholar.org/paper/afb8128b2c8016326131f5a12b657f2e9589a97f", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "28dafb94a87daa71ad3edf9f04f3c8c32753398b", "title": "Improving Code Generation by Training with Natural Language Feedback", "abstract": "The potential for pre-trained large language models (LLMs) to use natural language feedback at inference time has been an exciting recent development. We build upon this observation by formalizing an algorithm for learning from natural language feedback at training time instead, which we call Imitation learning from Language Feedback (ILF). ILF requires only a small amount of human-written feedback during training and does not require the same feedback at test time, making it both user-friendly and sample-efficient. We further show that ILF can be seen as a form of minimizing the KL divergence to the ground truth distribution and demonstrate a proof-of-concept on a neural program synthesis task. We use ILF to improve a Codegen-Mono 6.1B model's pass@1 rate by 38% relative (and 10% absolute) on the Mostly Basic Python Problems (MBPP) benchmark, outperforming both fine-tuning on MBPP and fine-tuning on repaired programs written by humans. Overall, our results suggest that learning from human-written natural language feedback is both more effective and sample-efficient than training exclusively on demonstrations for improving an LLM's performance on code generation tasks.", "year": 2023, "publicationDate": "2023-03-28", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2303.16749"}, "citationCount": 97, "referenceCount": 36, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2303.16749", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "13336152", "name": "Angelica Chen"}], "url": "https://www.semanticscholar.org/paper/28dafb94a87daa71ad3edf9f04f3c8c32753398b", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "19ea368b7f88279899c40813a797dda7adc50c07", "title": "Outline, Then Details: Syntactically Guided Coarse-To-Fine Code Generation", "abstract": "For a complicated algorithm, its implementation by a human programmer usually starts with outlining a rough control flow followed by iterative enrichments, eventually yielding carefully generated syntactic structures and variables in a hierarchy. However, state-of-the-art large language models generate codes in a single pass, without intermediate warm-ups to reflect the structured thought process of\"outline-then-detail\". Inspired by the recent success of chain-of-thought prompting, we propose ChainCoder, a program synthesis language model that generates Python code progressively, i.e. from coarse to fine in multiple passes. We first decompose source code into layout frame components and accessory components via abstract syntax tree parsing to construct a hierarchical representation. We then reform our prediction target into a multi-pass objective, each pass generates a subsequence, which is concatenated in the hierarchy. Finally, a tailored transformer architecture is leveraged to jointly encode the natural language descriptions and syntactically aligned I/O data samples. Extensive evaluations show that ChainCoder outperforms state-of-the-arts, demonstrating that our progressive generation eases the reasoning procedure and guides the language model to generate higher-quality solutions. Our codes are available at: https://github.com/VITA-Group/ChainCoder.", "year": 2023, "publicationDate": "2023-04-28", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Machine Learning", "journal": {"pages": "42403-42419"}, "citationCount": 39, "referenceCount": 63, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2305.00909", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2152934619", "name": "Wenqing Zheng"}, {"authorId": "2005814581", "name": "S. Sharan"}, {"authorId": "145018564", "name": "Ajay Jaiswal"}, {"authorId": "1473176860", "name": "Kevin Wang"}, {"authorId": "2199014014", "name": "Yihan Xi"}, {"authorId": "1575684088", "name": "Dejia Xu"}, {"authorId": "2108404505", "name": "Zhangyang Wang"}], "url": "https://www.semanticscholar.org/paper/19ea368b7f88279899c40813a797dda7adc50c07", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "6a0f1a8a03baba3e54a1a2ef348a1b0c2b8dff4b", "title": "B-Coder: Value-Based Deep Reinforcement Learning for Program Synthesis", "abstract": "Program synthesis aims to create accurate, executable programs from problem specifications, specifically from natural language descriptions in our context. Recent studies have leveraged the power of reinforcement learning (RL) in conjunction with large language models (LLMs), significantly enhancing code generation capabilities. The application of RL focuses on directly optimizing for functional correctness, offering an advantage over conventional supervised methods. Despite policy-based RL methods dominating the literature on RL for program synthesis, the nature of program synthesis tasks hints at a natural alignment with value-based methods. This stems from the rich collection of off-policy programs, including those developed by human programmers and also historical samples, coupled with the straightforward verification of generated programs through automated unit testing, meaning rewards are easy to obtain. Diverging from the dominant use of policy-based algorithms, our work explores the feasibility of value-based approaches, leading to the development of our $\\mathcal{B}$-Coder (pronounced Bellman coder). Yet, training value-based methods presents challenges due to the enormous search space inherent to program synthesis. To this end, we introduce an initialization protocol for RL agents utilizing pre-trained LMs and a conservative Bellman operator to reduce training complexities. Moreover, we demonstrate how to leverage the learned value functions as a dual strategy to post-process generated programs. Our empirical evaluations demonstrated $\\mathcal{B}$-Coder's capability in achieving state-of-the-art performance when compared to policy-based methods. Remarkably, this achievement is reached with minimal reward engineering effort, highlighting the effectiveness of value-based RL, independent of reward designs.", "year": 2023, "publicationDate": "2023-10-04", "publicationTypes": ["JournalArticle"], "venue": "International Conference on Learning Representations", "journal": {"name": "ArXiv", "volume": "abs/2310.03173"}, "citationCount": 21, "referenceCount": 105, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2310.03173", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2143448562", "name": "Zishun Yu"}, {"authorId": "2256318649", "name": "Yunzhe Tao"}, {"authorId": "2254280307", "name": "Liyu Chen"}, {"authorId": "2088150138", "name": "Tao Sun"}, {"authorId": "2255392986", "name": "Hongxia Yang"}], "url": "https://www.semanticscholar.org/paper/6a0f1a8a03baba3e54a1a2ef348a1b0c2b8dff4b", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "dd4155515051bd9f6411244e5457aa93ff72cb44", "title": "Knowledge-Driven Robot Program Synthesis from Human VR Demonstrations", "abstract": "Aging societies, labor shortages and increasing wage costs call for assistance robots capable of autonomously performing a wide array of real-world tasks. Such open-ended robotic manipulation requires not only powerful knowledge representations and reasoning (KR&R) algorithms, but also methods for humans to instruct robots what tasks to perform and how to perform them. In this paper, we present a system for automatically generating executable robot control programs from human task demonstrations in virtual reality (VR). We leverage common-sense knowledge and game engine-based physics to semantically interpret human VR demonstrations, as well as an expressive and general task representation and automatic path planning and code generation, embedded into a state-of-the-art cognitive architecture. We demonstrate our approach in the context of force-sensitive fetch-and-place for a robotic shopping assistant. The source code is available at https://github.com/ease-crc/vr-program-synthesis.", "year": 2023, "publicationDate": "2023-06-05", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Principles of Knowledge Representation and Reasoning", "journal": {"pages": "34-43"}, "citationCount": 2, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2306.02739", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "20763559", "name": "Bastian Alt"}, {"authorId": "2026861852", "name": "Franklin Kenghagho Kenfack"}, {"authorId": "2121821", "name": "Andrei Haidu"}, {"authorId": "2711047", "name": "Darko Katic"}, {"authorId": "2097711638", "name": "Rainer Jakel"}, {"authorId": "1746229", "name": "M. Beetz"}], "url": "https://www.semanticscholar.org/paper/dd4155515051bd9f6411244e5457aa93ff72cb44", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "1a1fa9d1e4625f01794f73d0bc936974a02a032c", "title": "Program Synthesis for Cyber-Resilience", "abstract": "Architectural tactics enable stakeholders to achieve cyber-resilience requirements. They permit systems to react, resist, detect, and recover from cyber incidents. This paper presents an approach to generate source code for architectural tactics typically used in safety and mission-critical systems. Our approach extensively relies on the use of the Event-B formal method and the EventB2Java code generation plugin of the Rodin platform. It leverages the modeling of architectural tactics in the Event-B formal language and uses a set of EventB2Java transformation rules to generate certified code implementations for the said tactics. Since resilience requirements are statements about a system over time, and because of the fact that the Event-B language does not provide (native) support for the writing of temporal specifications, we have implemented a novel Linear Temporal Logic (LTL) extension for Event-B. We support several architectural tactics for availability, performance, and security. The generated code is certified in the following sense: discharging proof obligations in Rodin - the platform we use for writing the Event-B models - attests to the soundness of the architectural tactics modelled in Event-B, and the soundness of the translation encoded by the EventB2Java tool attests to the code correctness. Finally, we demonstrate the usability of our resilience validation approach with the aid of an Autonomous Vehicle System. It further helped us increase our confidence in the soundness of our Event-B LTL extension.", "year": 2023, "publicationDate": "2023-03-01", "publicationTypes": ["JournalArticle"], "venue": "IEEE Transactions on Software Engineering", "journal": {"name": "IEEE Transactions on Software Engineering", "pages": "962-972", "volume": "49"}, "citationCount": 6, "referenceCount": 32, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1768593", "name": "Néstor Cataño"}], "url": "https://www.semanticscholar.org/paper/1a1fa9d1e4625f01794f73d0bc936974a02a032c", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "8073f493f33842979d71c5b05bbbb276493d3c54", "title": "Function-constrained Program Synthesis", "abstract": "This work introduces (1) a technique that allows large language models (LLMs) to leverage user-provided code when solving programming tasks and (2) a method to iteratively generate modular sub-functions that can aid future code generation attempts when the initial code generated by the LLM is inadequate. Generating computer programs in general-purpose programming languages like Python poses a challenge for LLMs when instructed to use code provided in the prompt. Code-specific LLMs (e.g., GitHub Copilot, CodeLlama2) can generate code completions in real-time by drawing on all code available in a development environment. However, restricting code-specific LLMs to use only in-context code is not straightforward, as the model is not explicitly instructed to use the user-provided code and users cannot highlight precisely which snippets of code the model should incorporate into its context. Moreover, current systems lack effective recovery methods, forcing users to iteratively re-prompt the model with modified prompts until a sufficient solution is reached. Our method differs from traditional LLM-powered code-generation by constraining code-generation to an explicit function set and enabling recovery from failed attempts through automatically generated sub-functions. When the LLM cannot produce working code, we generate modular sub-functions to aid subsequent attempts at generating functional code. A by-product of our method is a library of reusable sub-functions that can solve related tasks, imitating a software team where efficiency scales with experience. We also introduce a new\"half-shot\"evaluation paradigm that provides tighter estimates of LLMs' coding abilities compared to traditional zero-shot evaluation. Our proposed evaluation method encourages models to output solutions in a structured format, decreasing syntax errors that can be mistaken for poor coding ability.", "year": 2023, "publicationDate": "2023-11-27", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2311.15500"}, "citationCount": 2, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2268404263", "name": "Patrick Hajali"}, {"authorId": "1951816", "name": "Ignas Budvytis"}], "url": "https://www.semanticscholar.org/paper/8073f493f33842979d71c5b05bbbb276493d3c54", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "b82d48f0946faa2894bd69c3947cf4fd328a81b4", "title": "LogoMotion: Visually-Grounded Code Synthesis for Creating and Editing Animation", "abstract": "Creating animation takes time, effort, and technical expertise. To help novices with animation, we present LogoMotion, an AI code generation approach that helps users create semantically meaningful animation for logos. LogoMotion automatically generates animation code with a method called visually-grounded code synthesis and program repair. This method performs visual analysis, instantiates a design concept, and conducts visual checking to generate animation code. LogoMotion provides novices with code-connected AI editing widgets that help them edit the motion, grouping, and timing of their animation. In a comparison study on 276 animations, LogoMotion was found to produce more content-aware animation than an industry-leading tool. In a user evaluation (n=16) comparing against a prompt-only baseline, these code-connected widgets helped users edit animations with control, iteration, and creative expression.", "year": 2024, "publicationDate": "2024-05-11", "publicationTypes": ["JournalArticle", "Book", "Conference"], "venue": "International Conference on Human Factors in Computing Systems", "journal": {"name": "Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems"}, "citationCount": 21, "referenceCount": 56, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2405.07065", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2301156066", "name": "Vivian Liu"}, {"authorId": "2820401", "name": "Rubaiat Habib Kazi"}, {"authorId": "2017467465", "name": "Li-Yi Wei"}, {"authorId": "2301151346", "name": "Matthew Fisher"}, {"authorId": "2301156025", "name": "Timothy Langlois"}, {"authorId": "2301179415", "name": "Seth Walker"}, {"authorId": "2283931524", "name": "Lydia B. Chilton"}], "url": "https://www.semanticscholar.org/paper/b82d48f0946faa2894bd69c3947cf4fd328a81b4", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "94f5f59e98c1ef87db6eace3e6b1ed916377c7ba", "title": "Automated C/C++ Program Repair for High-Level Synthesis via Large Language Models", "abstract": "In High-Level Synthesis (HLS), converting a regular C/C++ program into its HLS-compatible counterpart (HLS-C) still requires tremendous manual effort. Various program scripts have been introduced to automate this process. But the resulting codes usually contain many issues that should be manually repaired by developers. Since Large Language Models (LLMs) have the ability to automate code generation, they can also be used for automated program repair in HLS. However, due to the limited training of LLMs considering hardware and software simultaneously, hallucinations may occur during program repair using LLMs, leading to compilation failures. Besides, using LLMs for iterative repair also incurs a high cost. To address these challenges, we propose an LLM-driven program repair framework that takes regular $\\mathrm{C} / \\mathrm{C}++$ code as input and automatically generates its corresponding HLS-C code for synthesis while minimizing human repair effort. To mitigate the hallucinations in LLMs and enhance the prompt quality, a Retrieval-Augmented Generation (RAG) paradigm is introduced to guide the LLMs toward correct repair. In addition, we use LLMs to create a static bit width optimization program to identify the optimized bit widths for variables. Moreover, LLM-driven HLS optimization strategies are introduced to add/tune pragmas in HLS-C programs for circuit optimization. Experimental results demonstrate that the proposed LLM-driven automated framework can achieve much higher repair pass rates in 24 real-world applications compared with the traditional scripts and the direct application of LLMs for program repair. The codes are open-sourced at this link: https://github.com/code-source1/catapult.", "year": 2024, "publicationDate": "2024-07-04", "publicationTypes": ["JournalArticle", "Book"], "venue": "Workshop on Machine Learning for CAD", "journal": {"name": "2024 ACM/IEEE 6th Symposium on Machine Learning for CAD (MLCAD)", "pages": "1-9"}, "citationCount": 50, "referenceCount": 28, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1145/3670474.3685953", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2140062033", "name": "Kangwei Xu"}, {"authorId": "31602842", "name": "Grace Li Zhang"}, {"authorId": "35875297", "name": "Xunzhao Yin"}, {"authorId": "2248805727", "name": "Cheng Zhuo"}, {"authorId": "2071332998", "name": "Ulf Schlichtmann"}, {"authorId": "2269058160", "name": "Bing Li"}], "url": "https://www.semanticscholar.org/paper/94f5f59e98c1ef87db6eace3e6b1ed916377c7ba", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "5106c35f5baf26bcc322ac5403e935db628c14ba", "title": "Training Language Models on Synthetic Edit Sequences Improves Code Synthesis", "abstract": "Software engineers mainly write code by editing existing programs. In contrast, language models (LMs) autoregressively synthesize programs in a single pass. One explanation for this is the scarcity of sequential edit data. While high-quality instruction data for code synthesis is scarce, edit data for synthesis is even scarcer. To fill this gap, we develop a synthetic data generation algorithm called LintSeq. This algorithm refactors programs into sequences of synthetic edits by using a linter to procedurally sample across interdependent lines of source code. Synthetic edits sampled with LintSeq reflect the syntax and semantics of their programming language. To test the algorithm, we use it to refactor a dataset of instruction + program pairs into instruction + program-diff-sequence tuples. Then, we fine-tune a series of smaller LMs ranging from 2.6B to 14B parameters on both the re-factored and original versions of this dataset. We perform comprehensive evaluations comparing edit sequence code LMs against baselines on HumanEval, MBPP(+), CodeContests, DS-1000, and BigCodeBench. We show that models fine-tuned to iteratively synthesize code match or outperform baselines on pass@1, and exhibit better scaling across higher pass@k as a function of total test-time FLOPs. Finally, we also pretrain our own tiny LMs for code understanding. We show that fine-tuning these models to synthesize code edit-by-edit results in strong performance on HumanEval and MBPP(+) compared to existing code language models of similar scale such as CodeT5+, AlphaCode, and Codex.", "year": 2024, "publicationDate": "2024-10-03", "publicationTypes": ["JournalArticle"], "venue": "International Conference on Learning Representations", "journal": {"name": "ArXiv", "volume": "abs/2410.02749"}, "citationCount": 10, "referenceCount": 54, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2047734290", "name": "Ulyana Piterbarg"}, {"authorId": "2273667564", "name": "Lerrel Pinto"}, {"authorId": "2273646684", "name": "Rob Fergus"}], "url": "https://www.semanticscholar.org/paper/5106c35f5baf26bcc322ac5403e935db628c14ba", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "d182a68584c80ab58ff4ed325152be7dd041e046", "title": "Towards No-Code Programming of Cobots: Experiments with Code Synthesis by Large Code Models for Conversational Programming", "abstract": "While there has been a lot of research recently on robots in household environments, at the present time, most robots in existence can be found on shop floors, and most interactions between humans and robots happen there. ``Collaborative robots''(cobots) designed to work alongside humans on assembly lines traditionally require expert programming, limiting ability to make changes, or manual guidance, limiting expressivity of the resulting programs. To address these limitations, we explore using Large Language Models (LLMs), and in particular, their abilities of doing in-context learning, for conversational code generation. As a first step, we define RATS, the ``Repetitive Assembly Task'', a 2D building task designed to lay the foundation for simulating industry assembly scenarios. In this task, a `programmer'instructs a cobot, using natural language, on how a certain assembly is to be built; that is, the programmer induces a program, through natural language. We create a dataset that pairs target structures with various example instructions (human-authored, template-based, and model-generated) and example code. With this, we systematically evaluate the capabilities of state-of-the-art LLMs for synthesising this kind of code, given in-context examples. Evaluating in a simulated environment, we find that LLMs are capable of generating accurate `first order code'(instruction sequences), but have problems producing `higher-order code'(abstractions such as functions, or use of loops).", "year": 2024, "publicationDate": "2024-09-17", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.11041"}, "citationCount": 3, "referenceCount": 61, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2046531185", "name": "Chalamalasetti Kranti"}, {"authorId": "2079305", "name": "Sherzod Hakimov"}, {"authorId": "2257274000", "name": "David Schlangen"}], "url": "https://www.semanticscholar.org/paper/d182a68584c80ab58ff4ed325152be7dd041e046", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "148a2dd31775ec743b4120e99253046270d551a8", "title": "Learning to Reason via Program Generation, Emulation, and Search", "abstract": "Program synthesis with language models (LMs) has unlocked a large set of reasoning abilities; code-tuned LMs have proven adept at generating programs that solve a wide variety of algorithmic symbolic manipulation tasks (e.g. word concatenation). However, not all reasoning tasks are easily expressible as code, e.g. tasks involving commonsense reasoning, moral decision-making, and sarcasm understanding. Our goal is to extend an LM's program synthesis skills to such tasks and evaluate the results via pseudo-programs, namely Python programs where some leaf function calls are left undefined. To that end, we propose, Code Generation and Emulated EXecution (CoGEX). CoGEX works by (1) training LMs to generate pseudo-programs, (2) teaching them to emulate their generated program's execution, including those leaf functions, allowing the LM's knowledge to fill in the execution gaps; and (3) using them to search over many programs to find an optimal one. To adapt the CoGEX model to a new task, we introduce a method for performing program search to find a single program whose pseudo-execution yields optimal performance when applied to all the instances of a given dataset. We show that our approach yields large improvements compared to standard in-context learning approaches on a battery of tasks, both algorithmic and soft reasoning. This result thus demonstrates that code synthesis can be applied to a much broader class of problems than previously considered. Our released dataset, fine-tuned models, and implementation can be found at \\url{https://github.com/nweir127/CoGEX}.", "year": 2024, "publicationDate": "2024-05-25", "publicationTypes": ["JournalArticle"], "venue": "Neural Information Processing Systems", "journal": {"name": "ArXiv", "volume": "abs/2405.16337"}, "citationCount": 15, "referenceCount": 45, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "38912638", "name": "Nathaniel Weir"}, {"authorId": "2261284957", "name": "Muhammad Khalifa"}, {"authorId": "2257459530", "name": "Linlu Qiu"}, {"authorId": "47433471", "name": "Orion Weller"}, {"authorId": "2303381821", "name": "Peter Clark"}], "url": "https://www.semanticscholar.org/paper/148a2dd31775ec743b4120e99253046270d551a8", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "efcc35a24c5f3da7bf56b8ce390e1b5a7d77508f", "title": "Reinforcement Learning and Data-Generation for Syntax-Guided Synthesis", "abstract": "Program synthesis is the task of automatically generating code based on a specification. In Syntax-Guided Synthesis (SyGuS) this specification is a combination of a syntactic template and a logical formula, and the result is guaranteed to satisfy both. We present a reinforcement-learning guided algorithm for SyGuS which uses Monte-Carlo Tree Search (MCTS) to search the space of candidate solutions. Our algorithm learns policy and value functions which, combined with the upper confidence bound for trees, allow it to balance exploration and exploitation. A common challenge in applying machine learning approaches to syntax-guided synthesis is the scarcity of training data. To address this, we present a method for automatically generating training data for SyGuS based on anti-unification of existing first-order satisfiability problems, which we use to train our MCTS policy. We implement and evaluate this setup and demonstrate that learned policy and value improve the synthesis performance over a baseline by over 26 percentage points in the training and testing sets. Our tool outperforms state-of-the-art tool cvc5 on the training set and performs comparably in terms of the total number of problems solved on the testing set (solving 23% of the benchmarks on which cvc5 fails). We make our data set publicly available, to enable further application of machine learning methods to the SyGuS problem.", "year": 2023, "publicationDate": "2023-07-13", "publicationTypes": ["JournalArticle", "Conference"], "venue": "AAAI Conference on Artificial Intelligence", "journal": {"pages": "10670-10678"}, "citationCount": 7, "referenceCount": 45, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://ojs.aaai.org/index.php/AAAI/article/download/28938/29783", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "25161908", "name": "Julian Parsert"}, {"authorId": "2346882258", "name": "Elizabeth Polgreen"}], "url": "https://www.semanticscholar.org/paper/efcc35a24c5f3da7bf56b8ce390e1b5a7d77508f", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "a23d109578ebe16652df0fdd46c4c11476c309e0", "title": "From Code to Play: Benchmarking Program Search for Games Using Large Language Models", "abstract": "Large language models (LLMs) have shown impressive capabilities in generating program code, opening exciting opportunities for applying program synthesis to games. In this work, we explore the potential of LLMs to directly synthesize usable code for a wide range of gaming applications, focusing on two programming languages, Python and Java. We use an evolutionary hill-climbing algorithm, where the mutations and seeds of the initial programs are controlled by LLMs. For Python, the framework covers various game-related tasks, including five miniature versions of Atari games, ten levels of Baba is You, an environment inspired by Asteroids, and a maze generation task. For Java, the framework contains 12 games from the TAG tabletop games framework. Across 29 tasks, we evaluated 12 language models for Python and 8 for Java. Our findings suggest that the performance of LLMs depends more on the task than on model size. While larger models generate more executable programs, these do not always result in higher-quality solutions but are much more expensive. No model has a clear advantage, although on any specific task, one model may be better. Trying many models on a problem and using the best results across them is more reliable than using just one.", "year": 2024, "publicationDate": "2024-12-05", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2412.04057"}, "citationCount": 6, "referenceCount": 56, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2202418971", "name": "Manuel Eberhardinger"}, {"authorId": "36470146", "name": "J. Goodman"}, {"authorId": "2389334100", "name": "Alexander Dockhorn"}, {"authorId": "1389741275", "name": "Diego Pérez-Liébana"}, {"authorId": "9213536", "name": "Raluca D. Gaina"}, {"authorId": "2333894101", "name": "Duygu cCakmak"}, {"authorId": "1822482", "name": "Setareh Maghsudi"}, {"authorId": "2277785011", "name": "Simon Lucas"}], "url": "https://www.semanticscholar.org/paper/a23d109578ebe16652df0fdd46c4c11476c309e0", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "05cd63fe72698f9c0db47d4d2c086a0de4327767", "title": "Do Programs Dream of Electromagnetic Signals? Towards GAN-based Code-to-Signal Synthesis", "abstract": "The analysis of EM signals has become a popular approach as a means for achieving non-intrusive and external anomaly detection, particularly in the realm of embedded devices. Previous efforts have shown huge potential in terms of discriminative precision between those signals that correspond to normal versus anomalous operations. However, virtually all research in the area neglects the challenge of gathering high-quality signals for the purpose of fingerprinting all possible execution paths of a program. Today, such efforts are mainly human-driven and because there may be hundreds of alternative paths even in simple programs, EM-based anomaly detection approaches exhibit poor scalability. In this work, we introduce a set of methods for the generation of EM signals directly from code. To the best of our knowledge, this is the first effort that aims to address code-to-signal synthesis for purposes of side-channel analysis. The proposed framework is based on Generative Adversarial Networks (GAN) that receive the corresponding assembly (ASM) code of a program as input and in turn produce artificial signals which bear near-identical morphological characteristics as the corresponding real EM signals. Although the proposed method pertains across a wide range of applications we have evaluated our approach specifically for the task of training anomaly detection models. We experimentally showed that synthetic signals can train models that can then detect even stealthy code injection attacks i.e., very challenging minimal code alterations with great accuracy. More specifically, synthetically trained anomaly detection models achieve a near-perfect AUC score of 0.993 for the detection of four malicious instructions and 0.981 for the detection of two malicious instructions. Interestingly, applying rudimentary feature engineering i.e., considering the maximum amplitude of the signal per cycle as opposed to the entire raw signal leads to perfect detection accuracy.", "year": 2023, "publicationDate": "2023-10-30", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE Military Communications Conference", "journal": {"name": "MILCOM 2023 - 2023 IEEE Military Communications Conference (MILCOM)", "pages": "716-721"}, "citationCount": 2, "referenceCount": 20, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2196143149", "name": "Kurt A. Vedros"}, {"authorId": "2219222", "name": "C. Kolias"}, {"authorId": "19174398", "name": "Robert C. Ivans"}], "url": "https://www.semanticscholar.org/paper/05cd63fe72698f9c0db47d4d2c086a0de4327767", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "ba2d0589cb25c0529c2bd395f3c6b3a2d07c786b", "title": "Learning-Based Automatic Synthesis of Software Code and Configuration", "abstract": "Increasing demands in software industry and scarcity of software engineers motivates researchers and practitioners to automate the process of software generation and configuration. Large scale automatic software generation and configuration is a very complex and challenging task. In this proposal, we set out to investigate this problem by breaking down automatic software generation and configuration into two different tasks. In first task, we propose to synthesize software automatically with input output specifications. This task is further broken down into two sub-tasks. The first sub-task is about synthesizing programs with a genetic algorithm which is driven by a neural network based fitness function trained with program traces and specifications. For the second sub-task, we formulate program synthesis as a continuous optimization problem and synthesize programs with covariance matrix adaption evolutionary strategy (a state-of-the-art continuous optimization method). Finally, for the second task, we propose to synthesize configurations of large scale software from different input files (e.g. software manuals, configurations files, online blogs, etc.) using a sequence-to-sequence deep learning mechanism.", "year": 2023, "publicationDate": "2023-05-25", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2305.15642"}, "citationCount": 0, "referenceCount": 60, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2305.15642", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "48172721", "name": "Shantanu Mandal"}], "url": "https://www.semanticscholar.org/paper/ba2d0589cb25c0529c2bd395f3c6b3a2d07c786b", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "ddb815ed9e291b2cb0678bf0754895f253732aa9", "title": "The Program Testing Ability of Large Language Models for Code", "abstract": "Recent development of large language models (LLMs) for code like CodeX and CodeT5+ shows promise in achieving code intelligence. Their ability of synthesizing program targeting a pre-defined algorithmic coding task has been intensively tested and verified on datasets including HumanEval and MBPP. Yet, evaluation of these LLMs from more perspectives (than just program synthesis) is also anticipated, considering their broad scope of applications. In this paper, we explore their ability of automatic test cases generation. We show intriguing observations and reveal how the quality of their generated test cases can be improved. Following recent work which uses generated test cases to enhance program synthesis, we further leverage our findings in improving the quality of the synthesized programs and show +11.77% and +4.22% higher code pass rates on HumanEval+ comparing with the GPT-3.5-turbo baseline and the recent state-of-the-art, respectively. Our code is publicly available at https://github.com/asdasxzxcq/TestCaseGen.", "year": 2023, "publicationDate": "2023-10-09", "publicationTypes": ["JournalArticle", "Conference"], "venue": "Conference on Empirical Methods in Natural Language Processing", "journal": {"pages": "23-34"}, "citationCount": 19, "referenceCount": 42, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2310.05727", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2386786906", "name": "Weimin Xiong"}, {"authorId": "2243697097", "name": "Yiwen Guo"}, {"authorId": "2257354587", "name": "Hao Chen"}], "url": "https://www.semanticscholar.org/paper/ddb815ed9e291b2cb0678bf0754895f253732aa9", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "b54a3b0b2ddac1986df20adbb5bc0e2f55018bbd", "title": "High-Level Synthesis of the OpenMP runtime to improve the generation of parallel accelerators", "abstract": "Field Programmable Gate Arrays (FPGAs) are reconfigurable hardware components that can be programmed using a hardware specification language such as Verilog or VHDL.Writing code to program an FPGA requires a set of different skills than software programming, for example, related to the use of signals and registers instead of variables and the explicit description of parallelism. High-Level Synthesis (HLS) tools can help by automatically translating software specifications into hardware descriptions.", "year": 2023, "publicationDate": "2023-05-09", "publicationTypes": ["JournalArticle", "Book"], "venue": "ACM International Conference on Computing Frontiers", "journal": {"name": "Proceedings of the 20th ACM International Conference on Computing Frontiers"}, "citationCount": 0, "referenceCount": 4, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://dl.acm.org/doi/pdf/10.1145/3587135.3592182", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2205540124", "name": "Giovanni Gozzi"}, {"authorId": "2044706017", "name": "M. Fiorito"}, {"authorId": "2044708119", "name": "S. Curzel"}, {"authorId": "1842209", "name": "Fabrizio Ferrandi"}], "url": "https://www.semanticscholar.org/paper/b54a3b0b2ddac1986df20adbb5bc0e2f55018bbd", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "f1239277af35b24e174aeb81a1225dfd1e5ff0c0", "title": "Generating Code World Models with Large Language Models Guided by Monte Carlo Tree Search", "abstract": "In this work we consider Code World Models, world models generated by a Large Language Model (LLM) in the form of Python code for model-based Reinforcement Learning (RL). Calling code instead of LLMs for planning has potential to be more precise, reliable, interpretable, and extremely efficient. However, writing appropriate Code World Models requires the ability to understand complex instructions, to generate exact code with non-trivial logic and to self-debug a long program with feedback from unit tests and environment trajectories. To address these challenges, we propose Generate, Improve and Fix with Monte Carlo Tree Search (GIF-MCTS), a new code generation strategy for LLMs. To test our approach in an offline RL setting, we introduce the Code World Models Benchmark (CWMB), a suite of program synthesis and planning tasks comprised of 18 diverse RL environments paired with corresponding textual descriptions and curated trajectories. GIF-MCTS surpasses all baselines on the CWMB and two other benchmarks, and we show that the Code World Models synthesized with it can be successfully used for planning, resulting in model-based RL agents with greatly improved sample efficiency and inference speed.", "year": 2024, "publicationDate": "2024-05-24", "publicationTypes": ["JournalArticle"], "venue": "Neural Information Processing Systems", "journal": {"name": "ArXiv", "volume": "abs/2405.15383"}, "citationCount": 41, "referenceCount": 68, "influentialCitationCount": 3, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2273550686", "name": "Nicola Dainese"}, {"authorId": "2298964763", "name": "Matteo Merler"}, {"authorId": "2112206379", "name": "Minttu Alakuijala"}, {"authorId": "2265492561", "name": "Pekka Marttinen"}], "url": "https://www.semanticscholar.org/paper/f1239277af35b24e174aeb81a1225dfd1e5ff0c0", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "82760fe86186a287f62fd44e9225460b8f8aad00", "title": "Mitigating Gender Bias in Code Large Language Models via Model Editing", "abstract": "In recent years, with the maturation of large language model (LLM) technology and the emergence of high-quality programming code datasets, researchers have become increasingly confident in addressing the challenges of program synthesis automatically. However, since most of the training samples for LLMs are unscreened, it is inevitable that LLMs' performance may not align with real-world scenarios, leading to the presence of social bias. To evaluate and quantify the gender bias in code LLMs, we propose a dataset named CodeGenBias (Gender Bias in the Code Generation) and an evaluation metric called FB-Score (Factual Bias Score) based on the actual gender distribution of correlative professions. With the help of CodeGenBias and FB-Score, we evaluate and analyze the gender bias in eight mainstream Code LLMs. Previous work has demonstrated that model editing methods that perform well in knowledge editing have the potential to mitigate social bias in LLMs. Therefore, we develop a model editing approach named MG-Editing (Multi-Granularity model Editing), which includes the locating and editing phases. Our model editing method MG-Editing can be applied at five different levels of model parameter granularity: full parameters level, layer level, module level, row level, and neuron level. Extensive experiments not only demonstrate that our MG-Editing can effectively mitigate the gender bias in code LLMs while maintaining their general code generation capabilities, but also showcase its excellent generalization. At the same time, the experimental results show that, considering both the gender bias of the model and its general code generation capability, MG-Editing is most effective when applied at the row and neuron levels of granularity.", "year": 2024, "publicationDate": "2024-10-10", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2410.07820"}, "citationCount": 4, "referenceCount": 58, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2308095876", "name": "Zhanyue Qin"}, {"authorId": "2277689256", "name": "H. Wang"}, {"authorId": "2294767159", "name": "Zecheng Wang"}, {"authorId": "2293768616", "name": "Deyuan Liu"}, {"authorId": "117639306", "name": "Cunhang Fan"}, {"authorId": "2308631023", "name": "Zhao Lv"}, {"authorId": "2282568037", "name": "Zhiying Tu"}, {"authorId": "2249633557", "name": "Dianhui Chu"}, {"authorId": "2261388493", "name": "Dianbo Sui"}], "url": "https://www.semanticscholar.org/paper/82760fe86186a287f62fd44e9225460b8f8aad00", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "80ad887805d42e03d3a17cee3ea881c01283af4e", "title": "Constrained Decoding for Fill-in-the-Middle Code Language Models via Efficient Left and Right Quotienting of Context-Sensitive Grammars", "abstract": "Large Language Models are powerful tools for program synthesis and advanced auto-completion, but come with no guarantee that their output code is syntactically correct. This paper contributes an incremental parser that allows early rejection of syntactically incorrect code, as well as efficient detection of complete programs for fill-in-the-middle (FIM) tasks. We extend the Earley parsing algorithm to allow for left and right quotients of context-free grammars, and develop methods to handle quotienting of several context-sensitive features present in the grammars of many common programming languages. The result of these contributions is an efficient, general, and well-grounded method for left and right quotient parsing. To validate our theoretical contributions -- and the effectiveness of certain design decisions -- we evaluate our method on the particularly difficult case of FIM completion for Python 3, with syntax-correctness constraints. Our results demonstrate that constrained generation can significantly reduce the incidence of syntax errors in recommended code.", "year": 2024, "publicationDate": "2024-02-28", "publicationTypes": [], "venue": null, "journal": null, "citationCount": 8, "referenceCount": 27, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2287921227", "name": "Daniel Melcer"}, {"authorId": "2287921064", "name": "N. Fulton"}, {"authorId": "40892818", "name": "Sanjay Krishna Gouda"}, {"authorId": "2287922898", "name": "Haifeng Qian"}], "url": "https://www.semanticscholar.org/paper/80ad887805d42e03d3a17cee3ea881c01283af4e", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "f0db9f97b5b84ab0cfaa472206c1627e65c0d373", "title": "LILO: Learning Interpretable Libraries by Compressing and Documenting Code", "abstract": "While large language models (LLMs) now excel at code generation, a key aspect of software development is the art of refactoring: consolidating code into libraries of reusable and readable programs. In this paper, we introduce LILO, a neurosymbolic framework that iteratively synthesizes, compresses, and documents code to build libraries tailored to particular problem domains. LILO combines LLM-guided program synthesis with recent algorithmic advances in automated refactoring from Stitch: a symbolic compression system that efficiently identifies optimal lambda abstractions across large code corpora. To make these abstractions interpretable, we introduce an auto-documentation (AutoDoc) procedure that infers natural language names and docstrings based on contextual examples of usage. In addition to improving human readability, we find that AutoDoc boosts performance by helping LILO's synthesizer to interpret and deploy learned abstractions. We evaluate LILO on three inductive program synthesis benchmarks for string editing, scene reasoning, and graphics composition. Compared to existing neural and symbolic methods - including the state-of-the-art library learning algorithm DreamCoder - LILO solves more complex tasks and learns richer libraries that are grounded in linguistic knowledge.", "year": 2023, "publicationDate": "2023-10-30", "publicationTypes": ["JournalArticle"], "venue": "International Conference on Learning Representations", "journal": {"name": "ArXiv", "volume": "abs/2310.19791"}, "citationCount": 44, "referenceCount": 88, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "35748708", "name": "Gabriel Grand"}, {"authorId": "2147199509", "name": "L. Wong"}, {"authorId": "2058735196", "name": "Matthew Bowers"}, {"authorId": "1689656957", "name": "Theo X. Olausson"}, {"authorId": "2264511729", "name": "Muxin Liu"}, {"authorId": "2238317928", "name": "J. B. Tenenbaum"}, {"authorId": "2264203454", "name": "Jacob Andreas"}], "url": "https://www.semanticscholar.org/paper/f0db9f97b5b84ab0cfaa472206c1627e65c0d373", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "da883f67a22f8be1aa4d22f45ba84e204e5673fb", "title": "Generation of Compiler Backends from Formal Models of Hardware", "abstract": "Compilers convert between representations -- usually, from higher-level, human writable code to lower-level, machine-readable code. A compiler backend is the portion of the compiler containing optimizations and code generation routines for a specific hardware target. In this dissertation, I advocate for a specific way of building compiler backends: namely, by automatically generating them from explicit, formal models of hardware using automated reasoning algorithms. I describe how automatically generating compilers from formal models of hardware leads to increased optimization ability, stronger correctness guarantees, and reduced development time for compiler backends. As evidence, I present two case studies: first, Glenside, which uses equality saturation to increase the 3LA compiler's ability to offload operations to machine learning accelerators, and second, Lakeroad, a technology mapper for FPGAs which uses program synthesis and semantics extracted from Verilog to map hardware designs to complex, programmable hardware primitives.", "year": 2024, "publicationDate": "2024-08-27", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2408.15429"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "40949637", "name": "Gus Henry Smith"}], "url": "https://www.semanticscholar.org/paper/da883f67a22f8be1aa4d22f45ba84e204e5673fb", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "79680e20f0c8038039b243fb5fd385fbe967c799", "title": "Controlling Large Language Models to Generate Secure and Vulnerable Code", "abstract": null, "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2302.05319"}, "citationCount": 22, "referenceCount": 54, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "8516542", "name": "Jingxuan He"}, {"authorId": "1736447", "name": "Martin T. Vechev"}], "url": "https://www.semanticscholar.org/paper/79680e20f0c8038039b243fb5fd385fbe967c799", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "399edc3a101e6f538d95c39db017c7a39445ab49", "title": "UniTSyn: A Large-Scale Dataset Capable of Enhancing the Prowess of Large Language Models for Program Testing", "abstract": "The remarkable capability of large language models (LLMs) in generating high-quality code has drawn increasing attention in the software testing community. However, existing code LLMs often demonstrate unsatisfactory capabilities in generating accurate, complete tests since they were trained on code snippets collected without differentiating between code for testing and for other purposes. In this paper, we present a large-scale dataset, UniTSyn, which can enhance LLMs for Unit Test Synthesis. Associating tests with the tested functions is crucial for LLMs to infer the expected behavior and the logic paths to be verified. By leveraging Language Server Protocol, UniTSyn achieves the challenging goal of collecting focal-test pairs without per-project execution setups or per-language heuristics, which tend to be fragile and difficult to scale. Containing 2.7 million focal-test pairs across five mainstream programming languages, it can enhance the test generation ability of LLMs. Our experiments demonstrate that, by building an autoregressive LLM based on UniTSyn, we can achieve significant benefits in learning and understanding unit test representations, resulting in improved generation accuracy and code coverage across all the evaluated programming languages.", "year": 2024, "publicationDate": "2024-02-04", "publicationTypes": ["Book", "JournalArticle", "Conference"], "venue": "International Symposium on Software Testing and Analysis", "journal": {"name": "Proceedings of the 33rd ACM SIGSOFT International Symposium on Software Testing and Analysis"}, "citationCount": 24, "referenceCount": 74, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2402.03396", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2118918598", "name": "Yifeng He"}, {"authorId": "2243309683", "name": "Jiabo Huang"}, {"authorId": "144278456", "name": "Yuyang Rong"}, {"authorId": "2243697097", "name": "Yiwen Guo"}, {"authorId": "2283096002", "name": "Ethan Wang"}, {"authorId": "2257354587", "name": "Hao Chen"}], "url": "https://www.semanticscholar.org/paper/399edc3a101e6f538d95c39db017c7a39445ab49", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "01ffc083b82aa3040062aecd23bc18b3d6132578", "title": "Matching Linear Algebra and Tensor Code to Specialized Hardware Accelerators", "abstract": "Dedicated tensor accelerators demonstrate the importance of linear algebra in modern applications. Such accelerators have the potential for impressive performance gains, but require programmers to rewrite code using vendor APIs - a barrier to wider scale adoption. Recent work overcomes this by matching and replacing patterns within code, but such approaches are fragile and fail to cope with the diversity of real-world codes. We develop ATC, a compiler that uses program synthesis to map regions of code to specific APIs. The mapping space that ATC explores is combinatorially large, requiring the development of program classification, dynamic analysis, variable constraint generation and lexical distance matching techniques to make it tractable. We apply ATC to real-world tensor and linear algebra codes and evaluate them against four state-of-the-art approaches. We accelerate between 2.6x and 7x more programs, leading to over an order of magnitude performance improvement.", "year": 2023, "publicationDate": "2023-01-27", "publicationTypes": ["Book", "JournalArticle", "Conference"], "venue": "International Conference on Compiler Construction", "journal": {"name": "Proceedings of the 32nd ACM SIGPLAN International Conference on Compiler Construction"}, "citationCount": 12, "referenceCount": 71, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://dl.acm.org/doi/pdf/10.1145/3578360.3580262", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2185593294", "name": "Pablo Antonio Mart'inez"}, {"authorId": "1423372001", "name": "Jackson Woodruff"}, {"authorId": "1405319696", "name": "Jordi Armengol-Estap'e"}, {"authorId": "2084043446", "name": "Gregorio Bernabé"}, {"authorId": "2203317597", "name": "J. M. Garc'ia"}, {"authorId": "1401533251", "name": "M. O’Boyle"}], "url": "https://www.semanticscholar.org/paper/01ffc083b82aa3040062aecd23bc18b3d6132578", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "d9bd490aba3a7995f728594403b3358cb79aacd6", "title": "Synthesis of Mathematical programs from Natural Language Specifications", "abstract": "Several decision problems that are encountered in various business domains can be modeled as mathematical programs, i.e. optimization problems. The process of conducting such modeling often requires the involvement of experts trained in operations research and advanced algorithms. Surprisingly, despite the significant advances in the methods for program and code synthesis, AutoML, learning to optimize etc., there has been little or no attention paid to automating the task of synthesizing mathematical programs. We imagine a scenario where the specifications for modeling, i.e. the objective and constraints are expressed in an unstructured form in natural language (NL) and the mathematical program has to be synthesized from such an NL specification. In this work we evaluate the efficacy of employing CodeT5 with data augmentation and post-processing of beams. We utilize GPT-3 with back translation for generation of synthetic examples. Further we apply rules of linear programming to score beams and correct beams based on common error patterns. We observe that with these enhancements CodeT5 base gives an execution accuracy of 0.73 which is significantly better than zero-shot execution accuracy of 0.41 by ChatGPT and 0.36 by Codex.", "year": 2023, "publicationDate": "2023-03-30", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2304.03287"}, "citationCount": 13, "referenceCount": 41, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2304.03287", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Business", "source": "s2-fos-model"}], "authors": [{"authorId": "2329571738", "name": "Ganesh Prasath"}, {"authorId": "40151143", "name": "S. Karande"}], "url": "https://www.semanticscholar.org/paper/d9bd490aba3a7995f728594403b3358cb79aacd6", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "b181c979a94a6cd019f2527da4c018de19c59371", "title": "WikiCoder: Learning to Write Knowledge-Powered Code", "abstract": "We tackle the problem of automatic generation of computer programs from a few pairs of input-output examples. The starting point of this work is the observation that in many applications a solution program must use external knowledge not present in the examples: we call such programs knowledge-powered since they can refer to information collected from a knowledge graph such as Wikipedia. This paper makes a first step towards knowledge-powered program synthesis. We present WikiCoder, a system building upon state of the art machine-learned program synthesizers and integrating knowledge graphs. We evaluate it to show its wide applicability over different domains and discuss its limitations. WikiCoder solves tasks that no program synthesizers were able to solve before thanks to the use of knowledge graphs, while integrating with recent developments in the field to operate at scale.", "year": 2023, "publicationDate": "2023-03-15", "publicationTypes": ["JournalArticle"], "venue": "SPIN", "journal": {"pages": "123-140"}, "citationCount": 0, "referenceCount": 31, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2303.08574", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2133332654", "name": "Théo Matricon"}, {"authorId": "8374944", "name": "Nathanaël Fijalkow"}, {"authorId": "2265101182", "name": "Gaëtan Margueritte"}], "url": "https://www.semanticscholar.org/paper/b181c979a94a6cd019f2527da4c018de19c59371", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "688a46050b8a0fa9c9d414af024f68c5c73df11c", "title": "Template-based Neural Program Repair", "abstract": "In recent years, template-based and NMT-based automated program repair methods have been widely studied and achieved promising results. However, there are still disadvantages in both methods. The template-based methods cannot fix the bugs whose types are beyond the capabilities of the templates and only use the syntax information to guide the patch synthesis, while the NMT-based methods intend to generate the small range of fixed code for better performance and may suffer from the OOV (Out-of-vocabulary) problem. To solve these problems, we propose a novel template-based neural program repair approach called TENURE to combine the template-based and NMT- based methods. First, we build two large-scale datasets for 35 fix templates from template-based method and one special fix template (single-line code generation) from NMT-based method, respectively. Second, the encoder-decoder models are adopted to learn deep semantic features for generating patch intermediate representations (IRs) for different templates. The optimized copy mechanism is also used to alleviate the OOV problem. Third, based on the combined patch IRs for different templates, three tools are developed to recover real patches from the patch IRs, replace the unknown tokens, and filter the patch candidates with compilation errors by leveraging the project-specific information. On Defects4J-vl.2, TENURE can fix 79 bugs and 52 bugs with perfect and Ochiai fault localization, respectively. It is able to repair 50 and 32 bugs as well on Defects4J-v2.0. Compared with the existing template-based and NMT-based studies, TENURE achieves the best performance in all experiments.", "year": 2023, "publicationDate": "2023-05-01", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Software Engineering", "journal": {"name": "2023 IEEE/ACM 45th International Conference on Software Engineering (ICSE)", "pages": "1456-1468"}, "citationCount": 26, "referenceCount": 56, "influentialCitationCount": 4, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "47101028", "name": "Xiangxin Meng"}, {"authorId": "2108599817", "name": "Xu Wang"}, {"authorId": "2108881199", "name": "Hongyu Zhang"}, {"authorId": "145631821", "name": "Hailong Sun"}, {"authorId": "2108871532", "name": "Xudong Liu"}, {"authorId": "1767378", "name": "Chunming Hu"}], "url": "https://www.semanticscholar.org/paper/688a46050b8a0fa9c9d414af024f68c5c73df11c", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "0b3c894f6b60032e0b720121e0060f72aff466c1", "title": "RetypeR: Integrated Retrieval-based Automatic Program Repair for Python Type Errors", "abstract": "Python is a widely popular dynamic programming language. While Python's dynamic type system facilitates the development of Python programs, it also introduces type errors at run-time which are often challenging to repair. Large language models (LLMs) have recently demonstrated impressive performance in code understanding and generation, and have been applied to patch synthesis. However, the ability of LLMs to repair type errors is often limited by their finite input context window, which may not fully encompass the repair information necessary for fixing a specific type error, such as valuable context code and fix patterns. In this paper, we introduce RetypeR, an integrated retrieval-based framework to repair Python type errors automatically. RetypeR comprises two stages: external retrieval and internal retrieval. The external retrieval stage retrieves applicable fix patterns from external code repositories containing historical error fixes via an abstract syntax tree (AST)-based retrieval strategy. In the internal retrieval stage, a novel fix ingredient retriever is designed to extract valuable repair ingredients from local context within source files based on both lexical and semantic similarity. To integrate the information retrieved from the aforementioned external and internal stages, RetypeR constructs context-aware repair prompts for LLMs to guide them in generating correct patches for type errors. We evaluate RetypeR on two real-world benchmarks, TypeBugs and BugsInPy. The experimental results demonstrate that RetypeR achieves state-of-the-art performance, improving the best baseline by 12.73% and 11.54% on TypeBugs and BugsInPy benchmarks, respectively.", "year": 2024, "publicationDate": "2024-10-06", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Software Maintenance and Evolution", "journal": {"name": "2024 IEEE International Conference on Software Maintenance and Evolution (ICSME)", "pages": "199-210"}, "citationCount": 3, "referenceCount": 43, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2273981066", "name": "Sichong Hao"}, {"authorId": "2274082995", "name": "Xianjun Shi"}, {"authorId": "2274076318", "name": "Hongwei Liu"}], "url": "https://www.semanticscholar.org/paper/0b3c894f6b60032e0b720121e0060f72aff466c1", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "ae50c8e255ba55bdbbb05ea470aa63437534438e", "title": "Agentless: Demystifying LLM-based Software Engineering Agents", "abstract": "Recent advancements in large language models (LLMs) have significantly advanced the automation of software development tasks, including code synthesis, program repair, and test generation. More recently, researchers and industry practitioners have developed various autonomous LLM agents to perform end-to-end software development tasks. These agents are equipped with the ability to use tools, run commands, observe feedback from the environment, and plan for future actions. However, the complexity of these agent-based approaches, together with the limited abilities of current LLMs, raises the following question: Do we really have to employ complex autonomous software agents? To attempt to answer this question, we build Agentless -- an agentless approach to automatically solve software development problems. Compared to the verbose and complex setup of agent-based approaches, Agentless employs a simplistic three-phase process of localization, repair, and patch validation, without letting the LLM decide future actions or operate with complex tools. Our results on the popular SWE-bench Lite benchmark show that surprisingly the simplistic Agentless is able to achieve both the highest performance (32.00%, 96 correct fixes) and low cost ($0.70) compared with all existing open-source software agents! Furthermore, we manually classified the problems in SWE-bench Lite and found problems with exact ground truth patch or insufficient/misleading issue descriptions. As such, we construct SWE-bench Lite-S by excluding such problematic issues to perform more rigorous evaluation and comparison. Our work highlights the current overlooked potential of a simple, interpretable technique in autonomous software development. We hope Agentless will help reset the baseline, starting point, and horizon for autonomous software agents, and inspire future work along this crucial direction.", "year": 2024, "publicationDate": "2024-07-01", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2407.01489"}, "citationCount": 442, "referenceCount": 120, "influentialCitationCount": 74, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "145349987", "name": "Chun Xia"}, {"authorId": "2156356240", "name": "Yinlin Deng"}, {"authorId": "2309178028", "name": "S. Dunn"}, {"authorId": "2237429253", "name": "Lingming Zhang"}], "url": "https://www.semanticscholar.org/paper/ae50c8e255ba55bdbbb05ea470aa63437534438e", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "af9df109e409b485e1337362431ba61623195145", "title": "Top Leaderboard Ranking = Top Coding Proficiency, Always? EvoEval: Evolving Coding Benchmarks via LLM", "abstract": "LLMs have become the go-to choice for code generation tasks, with an exponential increase in the training, development, and usage of LLMs specifically for code generation. To evaluate the ability of LLMs on code, both academic and industry practitioners rely on popular handcrafted benchmarks. However, prior benchmarks contain only a very limited set of problems, both in quantity and variety. Further, due to popularity and age, many benchmarks are prone to data leakage where example solutions can be readily found on the web and thus potentially in training data. Such limitations inevitably lead us to inquire: Is the leaderboard performance on existing benchmarks reliable and comprehensive enough to measure the program synthesis ability of LLMs? To address this, we introduce EvoEval -- a program synthesis benchmark suite created by evolving existing benchmarks into different targeted domains for a comprehensive evaluation of LLM coding abilities. Our study on 51 LLMs shows that compared to the high performance obtained on standard benchmarks like HumanEval, there is a significant drop in performance (on average 39.4%) when using EvoEval. Additionally, the decrease in performance can range from 19.6% to 47.7%, leading to drastic ranking changes amongst LLMs and showing potential overfitting of existing benchmarks. Furthermore, we showcase various insights, including the brittleness of instruction-following models when encountering rewording or subtle changes as well as the importance of learning problem composition and decomposition. EvoEval not only provides comprehensive benchmarks, but can be used to further evolve arbitrary problems to keep up with advances and the ever-changing landscape of LLMs for code. We have open-sourced our benchmarks, tools, and complete LLM generations at https://github.com/evo-eval/evoeval", "year": 2024, "publicationDate": "2024-03-28", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2403.19114"}, "citationCount": 73, "referenceCount": 54, "influentialCitationCount": 5, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "145349987", "name": "Chun Xia"}, {"authorId": "2156356240", "name": "Yinlin Deng"}, {"authorId": "2237429253", "name": "Lingming Zhang"}], "url": "https://www.semanticscholar.org/paper/af9df109e409b485e1337362431ba61623195145", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "a669ea57529f4db630043c8c75d8f840c485d24d", "title": "RLTF: Reinforcement Learning from Unit Test Feedback", "abstract": "The goal of program synthesis, or code generation, is to generate executable code based on given descriptions. Recently, there has been an increasing number of studies employing reinforcement learning (RL) to improve the performance of large language models (LLMs) for code. However, current representative works either rely solely on offline frameworks, limiting the exploration of new sample spaces, or fall short in the utilization of unit test signals, not accounting for specific error locations within the code. To address these issues, we propose RLTF, i.e., Reinforcement Learning from Unit Test Feedback, a novel online RL framework with unit test feedback of multi-granularity for refining code LLMs. Our approach generates data in real-time during training and simultaneously utilizes fine-grained feedback signals to guide the model towards producing higher-quality code. Extensive experiments show that RLTF achieves state-of-the-art performance on the APPS and the MBPP benchmarks. Our code is available at: https://github.com/Zyq-scut/RLTF.", "year": 2023, "publicationDate": "2023-07-10", "publicationTypes": ["JournalArticle"], "venue": "Trans. Mach. Learn. Res.", "journal": {"name": "Trans. Mach. Learn. Res.", "volume": "2023"}, "citationCount": 137, "referenceCount": 34, "influentialCitationCount": 12, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2307.04349", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2108401097", "name": "Jiate Liu"}, {"authorId": "2269198306", "name": "Yiqin Zhu"}, {"authorId": "2105719095", "name": "Kaiwen Xiao"}, {"authorId": "2091914469", "name": "Qiang Fu"}, {"authorId": null, "name": "Xiao Han"}, {"authorId": "2005150594", "name": "Wei Yang"}, {"authorId": "2055648566", "name": "Deheng Ye"}], "url": "https://www.semanticscholar.org/paper/a669ea57529f4db630043c8c75d8f840c485d24d", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "8e7378140c002a34b7ac30fc1c1eaf1c5dac5ed5", "title": "Synergizing human expertise and AI efficiency with language model for microscopy operation and automated experiment design", "abstract": "With the advent of large language models (LLMs), in both the open source and proprietary domains, attention is turning to how to exploit such artificial intelligence (AI) systems in assisting complex scientific tasks, such as material synthesis, characterization, analysis and discovery. Here, we explore the utility of LLMs, particularly ChatGPT4, in combination with application program interfaces (APIs) in tasks of experimental design, programming workflows, and data analysis in scanning probe microscopy, using both in-house developed APIs and APIs given by a commercial vendor for instrument control. We find that the LLM can be especially useful in converting ideations of experimental workflows to executable code on microscope APIs. Beyond code generation, we find that the GPT4 is capable of analyzing microscopy images in a generic sense. At the same time, we find that GPT4 suffers from an inability to extend beyond basic analyses for more in-depth technical experimental design. We argue that an LLM specifically fine-tuned for individual scientific domains can potentially be a better language interface for converting scientific ideations from human experts to executable workflows. Such a synergy between human expertise and LLM efficiency in experimentation can open new doors for accelerating scientific research, enabling effective experimental protocols sharing in the scientific community.", "year": 2024, "publicationDate": "2024-01-24", "publicationTypes": ["JournalArticle"], "venue": "Machine Learning: Science and Technology", "journal": {"name": "Machine Learning: Science and Technology", "volume": "5"}, "citationCount": 35, "referenceCount": 51, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1088/2632-2153/ad52e9", "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1614041016", "name": "Yongtao Liu"}, {"authorId": "1388893794", "name": "M. Checa"}, {"authorId": "2269471288", "name": "Rama K. Vasudevan"}], "url": "https://www.semanticscholar.org/paper/8e7378140c002a34b7ac30fc1c1eaf1c5dac5ed5", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "94701d9c6cfc1aecc174ff62ccda939f790c1710", "title": "ReGAL: Refactoring Programs to Discover Generalizable Abstractions", "abstract": "While large language models (LLMs) are increasingly being used for program synthesis, they lack the global view needed to develop useful abstractions; they generally predict programs one at a time, often repeating the same functionality. Generating redundant code from scratch is both inefficient and error-prone. To address this, we propose Refactoring for Generalizable Abstraction Learning (ReGAL), a gradient-free method for learning a library of reusable functions via code refactorization, i.e., restructuring code without changing its execution output. ReGAL learns from a small set of existing programs, iteratively verifying and refining its abstractions via execution. We find that the shared function libraries discovered by ReGAL make programs easier to predict across diverse domains. On five datasets -- LOGO graphics generation, Date reasoning, TextCraft (a Minecraft-based text-game) MATH, and TabMWP -- both open-source and proprietary LLMs improve in accuracy when predicting programs with ReGAL functions. For CodeLlama-13B, ReGAL results in absolute accuracy increases of 11.5% on LOGO, 26.1% on date understanding, and 8.1% on TextCraft, outperforming GPT-3.5 in two of three domains. Our analysis reveals ReGAL's abstractions encapsulate frequently-used subroutines as well as environment dynamics.", "year": 2024, "publicationDate": "2024-01-29", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Machine Learning", "journal": {"name": "ArXiv", "volume": "abs/2401.16467"}, "citationCount": 30, "referenceCount": 71, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2281825070", "name": "Elias Stengel-Eskin"}, {"authorId": "1677896557", "name": "Archiki Prasad"}, {"authorId": "2281826842", "name": "Mohit Bansal"}], "url": "https://www.semanticscholar.org/paper/94701d9c6cfc1aecc174ff62ccda939f790c1710", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "85741da758cc3a37bc457b3dcff20b2114dc42f7", "title": "Statically Contextualizing Large Language Models with Typed Holes", "abstract": "Large language models (LLMs) have reshaped the landscape of program synthesis. However, contemporary LLM-based code completion systems often hallucinate broken code because they lack appropriate code context, particularly when working with definitions that are neither in the training data nor near the cursor. This paper demonstrates that tighter integration with the type and binding structure of the programming language in use, as exposed by its language server, can help address this contextualization problem in a token-efficient manner. In short, we contend that AIs need IDEs, too! In particular, we integrate LLM code generation into the Hazel live program sketching environment. The Hazel Language Server is able to identify the type and typing context of the hole that the programmer is filling, with Hazel’s total syntax and type error correction ensuring that a meaningful program sketch is available whenever the developer requests a completion. This allows the system to prompt the LLM with codebase-wide contextual information that is not lexically local to the cursor, nor necessarily in the same file, but that is likely to be semantically local to the developer’s goal. Completions synthesized by the LLM are then iteratively refined via further dialog with the language server, which provides error localization and error messages. To evaluate these techniques, we introduce MVUBench, a dataset of model-view-update (MVU) web applications with accompanying unit tests that have been written from scratch to avoid data contamination, and that can easily be ported to new languages because they do not have large external library dependencies. These applications serve as challenge problems due to their extensive reliance on application-specific data structures. Through an ablation study, we examine the impact of contextualization with type definitions, function headers, and errors messages, individually and in combination. We find that contextualization with type definitions is particularly impactful. After introducing our ideas in the context of Hazel, a low-resource language, we duplicate our techniques and port MVUBench to TypeScript in order to validate the applicability of these methods to higher-resource mainstream languages. Finally, we outline ChatLSP, a conservative extension to the Language Server Protocol (LSP) that language servers can implement to expose capabilities that AI code completion systems of various designs can use to incorporate static context when generating prompts for an LLM.", "year": 2024, "publicationDate": "2024-09-02", "publicationTypes": ["JournalArticle"], "venue": "Proc. ACM Program. Lang.", "journal": {"name": "Proceedings of the ACM on Programming Languages", "pages": "468 - 498", "volume": "8"}, "citationCount": 20, "referenceCount": 86, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1145/3689728", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2113663024", "name": "Andrew Blinn"}, {"authorId": "2345944265", "name": "Xiang Li"}, {"authorId": "2191043213", "name": "J. Kim"}, {"authorId": "2277849476", "name": "Cyrus Omar"}], "url": "https://www.semanticscholar.org/paper/85741da758cc3a37bc457b3dcff20b2114dc42f7", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "14d8a161e467cfb7d6ce6155ea35a683a18369c3", "title": "HumanEval on Latest GPT Models - 2024", "abstract": "In 2023, we are using the latest models of GPT-4 to advance program synthesis. The large language models have significantly improved the state-of-the-art for this purpose. To make these advancements more accessible, we have created a repository that connects these models to Huamn Eval. This dataset was initally developed to be used with a language model called CODEGEN on natural and programming language data. The utility of these trained models is showcased by demonstrating their competitive performance in zero-shot Python code generation on HumanEval tasks compared to previous state-of-the-art solutions. Additionally, this gives way to developing more multi-step paradigm synthesis. This benchmark features 160 diverse problem sets factorized into multistep prompts that our analysis shows significantly improves program synthesis over single-turn inputs. All code is open source at https://github.com/daniel442li/gpt-human-eval .", "year": 2024, "publicationDate": "2024-02-20", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2402.14852"}, "citationCount": 18, "referenceCount": 13, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2281079845", "name": "Daniel Li"}, {"authorId": "2286309017", "name": "Lincoln Murr"}], "url": "https://www.semanticscholar.org/paper/14d8a161e467cfb7d6ce6155ea35a683a18369c3", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "190a0ffb48e3f3ca8115f8e673f5ed98990ffed8", "title": "Large Language Models Synergize with Automated Machine Learning", "abstract": "Recently, program synthesis driven by large language models (LLMs) has become increasingly popular. However, program synthesis for machine learning (ML) tasks still poses significant challenges. This paper explores a novel form of program synthesis, targeting ML programs, by combining LLMs and automated machine learning (autoML). Specifically, our goal is to fully automate the generation and optimization of the code of the entire ML workflow, from data preparation to modeling and post-processing, utilizing only textual descriptions of the ML tasks. To manage the length and diversity of ML programs, we propose to break each ML program into smaller, manageable parts. Each part is generated separately by the LLM, with careful consideration of their compatibilities. To ensure compatibilities, we design a testing technique for ML programs. Unlike traditional program synthesis, which typically relies on binary evaluations (i.e., correct or incorrect), evaluating ML programs necessitates more than just binary judgments. Our approach automates the numerical evaluation and optimization of these programs, selecting the best candidates through autoML techniques. In experiments across various ML tasks, our method outperforms existing methods in 10 out of 12 tasks for generating ML programs. In addition, autoML significantly improves the performance of the generated ML programs. In experiments, given the textual task description, our method, Text-to-ML, generates the complete and optimized ML program in a fully autonomous process. The implementation of our method is available at https://github.com/JLX0/llm-automl.", "year": 2024, "publicationDate": "2024-05-06", "publicationTypes": ["JournalArticle"], "venue": "Trans. Mach. Learn. Res.", "journal": {"name": "Trans. Mach. Learn. Res.", "volume": "2024"}, "citationCount": 14, "referenceCount": 71, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2223017366", "name": "Jinglue Xu"}, {"authorId": "2108961682", "name": "Jialong Li"}, {"authorId": "2276983768", "name": "Zhen Liu"}, {"authorId": "2124290916", "name": "Nagar Anthel Venkatesh Suryanarayanan"}, {"authorId": "2213683981", "name": "Guoyuan Zhou"}, {"authorId": "2301157264", "name": "Jia Guo"}, {"authorId": "2247768141", "name": "Hitoshi Iba"}, {"authorId": "2238040359", "name": "Kenji Tei"}], "url": "https://www.semanticscholar.org/paper/190a0ffb48e3f3ca8115f8e673f5ed98990ffed8", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "3055348a730dcaa4d7634e13f6915db7d6628d0c", "title": "BatFix: Repairing language model-based transpilation", "abstract": "To keep up with changes in requirements, frameworks, and coding practices, software organizations might need to migrate code from one language to another. Source-to-source migration, or transpilation, is often a complex, manual process. Transpilation requires expertise both in the source and target language, making it highly laborious and costly. Languages models for code generation and transpilation are becoming increasingly popular. However, despite capturing code-structure well, code generated by language models is often spurious and contains subtle problems. We propose BatFix, a novel approach that augments language models for transpilation by leveraging program repair and synthesis to fix the code generated by these models. BatFix takes as input both the original program, the target program generated by the machine translation model, and a set of test cases and outputs a repaired program that passes all test cases. Experimental results show that our approach is agnostic to language models and programming languages. BatFix can locate bugs spawning multiple lines and synthesize patches for syntax and semantic bugs for programs migrated from Java to C++ and Python to C++ from multiple language models, including, OpenAI’s Codex.", "year": 2024, "publicationDate": "2024-04-12", "publicationTypes": ["JournalArticle"], "venue": "ACM Transactions on Software Engineering and Methodology", "journal": {"name": "ACM Transactions on Software Engineering and Methodology", "pages": "1 - 29", "volume": "33"}, "citationCount": 12, "referenceCount": 75, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://dl.acm.org/doi/pdf/10.1145/3658668", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2066472021", "name": "Daniel Ramos"}, {"authorId": "1773888", "name": "I. Lynce"}, {"authorId": "3094458", "name": "Vasco M. Manquinho"}, {"authorId": "2253457550", "name": "Ruben Martins"}, {"authorId": "2957803", "name": "Claire Le Goues"}], "url": "https://www.semanticscholar.org/paper/3055348a730dcaa4d7634e13f6915db7d6628d0c", "_run_id": "g1K2QeU5Og9zWCNnc", "_dataset_id": "v7awdONhx0Vmt26nx"}
{"paperId": "4bdcf2dd64af56f75b11f1648fcb0da53744a736", "title": "Biomarker Testing, Targeted Therapy and Clinical Trial Participation by Race Among Patients With Lung Cancer: A Real-World Medicaid Database Study", "abstract": "Introduction Biomarker testing in oncology is fundamental for targeted therapy use and clinical trial participation. Factors contributing to previously identified racial disparities in biomarker testing remain unclear. This study investigated biomarker testing, clinical trial participation, and targeted therapy by race among patients with metastatic lung cancer with Medicaid coverage in the United States. Methods The Merative MarketScan Medicaid claims database was used for this study to identify patients diagnosed with having metastatic lung cancer between 2017 and 2019 with at least 121 days of follow-up. Racial differences in biomarker testing, clinical trial enrollment, and targeted therapy use were analyzed using chi-square/t tests followed by logistic regression for confounding covariates. Results A total of 3845 patients were eligible. A total of 970 (25.2%) patients included in this study were Black. Biomarker testing was observed among 57.0%, targeted therapy among 4.6%, and 2.6% of the study cohort had evidence of clinical trial participation. No significant disparities between Black and White races were identified. Younger age and metastatic disease at initial diagnosis were the strongest independent factors associated with increased biomarker testing. Biomarker testing was positively associated with targeted therapy use (OR = 1.69, p = 0.005). Conclusions Patients with metastatic lung cancer with Medicaid coverage were found to have exceedingly low biomarker testing rates; only 57% had evidence of any biomarker testing. Although no consistent differences between Black and White races were identified, this study calls attention to care experienced by socioeconomically disadvantaged patients with metastatic lung cancer in the United States.", "year": 2024, "publicationDate": "2024-02-01", "publicationTypes": ["JournalArticle"], "venue": "JTO Clinical and Research Reports", "journal": {"name": "JTO Clinical and Research Reports", "volume": "5"}, "citationCount": 6, "referenceCount": 27, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.jtocrr.2024.100643", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2282772676", "name": "Debora S. Bruno"}, {"authorId": "2282906290", "name": "Xiaohong Li"}, {"authorId": "2250359773", "name": "Lisa M. Hess"}], "url": "https://www.semanticscholar.org/paper/4bdcf2dd64af56f75b11f1648fcb0da53744a736", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "da293b832107967204edbe991634964a1acb9783", "title": "Liquid biopsy, big data and artificial intelligence as a new global clinical trial model in targeted therapy", "abstract": "To this day, the phase III trial continues to be, as it was more than 60 years ago, the standard for the incorporation of new treatments in oncology. We currently have new tools such as NGS, Liquid Biopsy (LB), Big Data (BD) and Artificial Intelligence (AI) that will allow us to move towards faster and more universal research. This article analyzes the important weaknesses of phase III trials, the importance and current status of targeted therapy, and the contributions to LB decision-making and the knowledge of what happens in real life (RWD) that we facilitates BD and AI. Finally, what could be a clinical trial model that would take advantage of all these tools is proposed.", "year": 2023, "publicationDate": "2023-09-01", "publicationTypes": ["JournalArticle"], "venue": "The journal of liquid biopsy", "journal": {"name": "The Journal of Liquid Biopsy", "volume": "1"}, "citationCount": 3, "referenceCount": 13, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.jlb.2023.100008", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2240698457", "name": "Albert Abad"}, {"authorId": "2248219237", "name": "J. Vidal"}, {"authorId": "6204556", "name": "L. Layos"}, {"authorId": "2299444837", "name": "C. Morcillo"}, {"authorId": "2248900231", "name": "Izar Achaerandio"}, {"authorId": "2301447991", "name": "S. Viteri"}], "url": "https://www.semanticscholar.org/paper/da293b832107967204edbe991634964a1acb9783", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "548eeadfa6e53a8436afa10a409b6dcc85ea7027", "title": "Impact of pharmacist consultation at clinical trial inclusion: an effective way to reduce drug–drug interactions with oral targeted therapy", "abstract": null, "year": 2021, "publicationDate": "2021-07-20", "publicationTypes": ["JournalArticle"], "venue": "Cancer Chemotherapy and Pharmacology", "journal": {"name": "Cancer Chemotherapy and Pharmacology", "pages": "723 - 729", "volume": "88"}, "citationCount": 8, "referenceCount": 20, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1796778276", "name": "F. Leenhardt"}, {"authorId": "2098638705", "name": "Marie Alexandre"}, {"authorId": "5735390", "name": "S. Guiu"}, {"authorId": "8406999", "name": "S. Pouderoux"}, {"authorId": "6582602", "name": "Mélanie Beaujouin"}, {"authorId": "8872396", "name": "G. Lossaint"}, {"authorId": "6500470", "name": "L. Philibert"}, {"authorId": "2516975", "name": "A. Evrard"}, {"authorId": "6680194", "name": "W. Jacot"}], "url": "https://www.semanticscholar.org/paper/548eeadfa6e53a8436afa10a409b6dcc85ea7027", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "1f76195b83cf0a379c932c21d0cb19e3279d02a2", "title": "A randomized trial of consolidation-targeted adjuvant therapy with encorafenib and cetuximab versus usual care for patients with stage II/III BRAF V600E colon cancer: Alliance for Clinical Trials in Oncology A022004.", "abstract": "TPS3641 Background: Patients with mismatch repair proficient (pMMR) BRAF V600E mutant high-risk stage II (T4) or stage III colon cancer have a substantial risk of recurrence despite standard adjuvant therapy. In patients with metastatic BRAF V600E mutant colorectal cancer, the combination of the RAF inhibitor encorafenib and the EGFR inhibitor cetuximab has been shown to improve overall and progression-free survival compared to standard therapy after at least one prior line of therapy. This study will evaluate if this combination improves disease-free survival (DFS) in patients with resected BRAF V600E mutant pMMR/microsatellite stable (MSS) high-risk stage II (T4) or stage III colon cancer after standard adjuvant therapy. Methods: The study has a seamless phase II/III design, enrolling a maximum of 394 patients. BRAF mutation status can be determined locally or submitted for central testing in trial pre-screening. Eligible patients will be randomized 1:1 to usual surveillance versus 6 months of treatment with encorafenib (300mg oral daily) plus cetuximab (500mg/m2 intravenous every 14 days). Stratification factors are adjuvant chemotherapy regimen (FOLFOX versus CAPOX), duration of adjuvant therapy (3 months versus > 3 months), tumor stage (T4N0 versus T1-3N1 versus T4N1/TanyN2), and ctDNA marker status (detectable versus undetectable) at randomization. Adjuvant therapy must be completed at most 8 weeks prior to registration. For the phase II component, in the ctDNA detectable cohort, the primary endpoint will be ctDNA clearance rate at 6 months, and, in the ctDNA undetectable cohort, the primary endpoint will be 6-month ctDNA recurrence-free survival, where events consist of death, recurrence, or ctDNA positivity. The primary endpoint of the phase III component is DFS, and secondary endpoints are overall survival, adverse events, and alternative DFS calculated from the date of primary resection, rather than date of study randomization. Patient reported symptoms (PRO-CTCAE) will be collected and analyzed as an exploratory endpoint, and serial blood banking will support future correlative studies. The trial will proceed to the phase III portion if either of the two endpoints in the phase II cohorts is statistically superior in patients receiving encorafenib plus cetuximab. The phase III study sample size will provide 80% power at a one-sided α of 0.05 to detect an approximately 10% improvement in the three-year DFS rate, assuming 68% in the control arm. Two interim analyses will be performed for DFS endpoint. Support: U10CA180821, U10CA180882; https://acknowledgments.alliancefound.org . U10CA180820 (ECOG-ACRIN); U10CA180868 (NRG); U10CA180888 (SWOG); Pfizer, Eli Lilly; Clinicaltrials.gov ID: NCT05710406. Clinical trial information: NCT05710406 .", "year": 2023, "publicationDate": "2023-06-01", "publicationTypes": ["JournalArticle"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "4894739", "name": "R. Yaeger"}, {"authorId": "47528826", "name": "Q. Shi"}, {"authorId": "2555114", "name": "A. Dueck"}, {"authorId": "66373925", "name": "E. Dib"}, {"authorId": "33227846", "name": "S. M. Kazmi"}, {"authorId": "3757874", "name": "O. Alese"}, {"authorId": "31971547", "name": "S. Krishnamurthi"}, {"authorId": "6895980", "name": "A. Nixon"}, {"authorId": "3787220", "name": "A. Shergill"}, {"authorId": "1382512190", "name": "E. O’Reilly"}, {"authorId": "3859322", "name": "J. Meyerhardt"}], "url": "https://www.semanticscholar.org/paper/1f76195b83cf0a379c932c21d0cb19e3279d02a2", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "698f9a987521faaca5c3e580e9b02bd121fa7547", "title": "A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma", "abstract": null, "year": 2023, "publicationDate": "2023-03-29", "publicationTypes": ["JournalArticle"], "venue": "Journal of Neuro-Oncology", "journal": {"name": "Journal of Neuro-Oncology", "pages": "317-326", "volume": "162"}, "citationCount": 34, "referenceCount": 51, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2201232701", "name": "B. Zha"}, {"authorId": "82148411", "name": "Junping Yang"}, {"authorId": "2136862087", "name": "Qianqian Dang"}, {"authorId": "48982021", "name": "Peihong Li"}, {"authorId": "2213673318", "name": "Shuling Shi"}, {"authorId": "47875737", "name": "Jingjing Wu"}, {"authorId": "2201343587", "name": "Haiyang Cui"}, {"authorId": "2213040219", "name": "Linkuan Huangfu"}, {"authorId": "2213116484", "name": "Yuxin Li"}, {"authorId": "10296762", "name": "Daoke Yang"}, {"authorId": "46323180", "name": "Yingjuan Zheng"}], "url": "https://www.semanticscholar.org/paper/698f9a987521faaca5c3e580e9b02bd121fa7547", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "95eea64578438be854c2e6f1fc5658b923eb0f1d", "title": "Targeted therapy guided by circulating tumor DNA analysis in advanced gastrointestinal tumors", "abstract": "Although comprehensive genomic profiling has become standard in oncology for advanced solid tumors, the full potential of circulating tumor DNA (ctDNA)-based profiling in capturing tumor heterogeneity and guiding therapy selection remains underexploited, marked by a scarcity of evidence on its clinical impact and the assessment of intratumoral heterogeneity. The GOZILA study, a nationwide, prospective observational ctDNA profiling study, previously demonstrated higher clinical trial enrollment rates using liquid biopsy compared with tissue screening. This updated analysis of 4,037 patients further delineates the clinical utility of ctDNA profiling in advanced solid tumors, showcasing a significant enhancement in patient outcomes with a 24% match rate for targeted therapy. Patients treated with matched targeted therapy based on ctDNA profiling demonstrated significantly improved overall survival compared with those receiving unmatched therapy (hazard ratio, 0.54). Notably, biomarker clonality and adjusted plasma copy number were identified as predictors of therapeutic efficacy, reinforcing the value of ctDNA in reflecting tumor heterogeneity for precise treatment decisions. These new insights into the relationship between ctDNA characteristics and treatment outcomes advance our understanding beyond the initial enrollment benefits. Our findings advocate for the broader adoption of ctDNA-guided treatment, signifying an advancement in precision oncology and improving survival outcomes in advanced solid tumors. In the observational SCRUM-Japan GOZILA study, after a median follow-up of 11 months, patients with metastatic gastrointestinal tumors who received biomarker-matched therapies based on circulating tumor DNA profiling showed a greater clinical benefit than those receiving unmatched therapy.", "year": 2024, "publicationDate": "2024-09-16", "publicationTypes": ["JournalArticle"], "venue": "Nature Medicine", "journal": {"name": "Nature Medicine", "pages": "165 - 175", "volume": "31"}, "citationCount": 49, "referenceCount": 0, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://www.nature.com/articles/s41591-024-03244-8.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1958620496", "name": "Y. Nakamura"}, {"authorId": "2161870580", "name": "Hiroshi Ozaki"}, {"authorId": "47015370", "name": "M. Ueno"}, {"authorId": "2263849985", "name": "Y. Komatsu"}, {"authorId": "2249156720", "name": "S. Yuki"}, {"authorId": "40465243", "name": "T. Esaki"}, {"authorId": "7929339", "name": "H. Taniguchi"}, {"authorId": "4363110", "name": "Y. Sunakawa"}, {"authorId": "2301374827", "name": "Kensei Yamaguchi"}, {"authorId": "2228802193", "name": "Ken Kato"}, {"authorId": "2555327", "name": "T. Denda"}, {"authorId": "5517961", "name": "T. Nishina"}, {"authorId": "2266955528", "name": "Naoki Takahashi"}, {"authorId": "2283782893", "name": "T. Satoh"}, {"authorId": "6251238", "name": "H. Yasui"}, {"authorId": "2265565151", "name": "Hironaga Satake"}, {"authorId": "2280670640", "name": "E. Oki"}, {"authorId": "2110531943", "name": "T. Kato"}, {"authorId": "2262327899", "name": "Takashi Ohta"}, {"authorId": "5373296", "name": "N. Matsuhashi"}, {"authorId": "2267004188", "name": "Masahiro Goto"}, {"authorId": "9527188", "name": "N. Okano"}, {"authorId": "145792531", "name": "K. Ohtsubo"}, {"authorId": "2255337647", "name": "K. Yamazaki"}, {"authorId": "2262383404", "name": "Riu Yamashita"}, {"authorId": "2280393540", "name": "N. Iida"}, {"authorId": "28056624", "name": "Mihoko Yuasa"}, {"authorId": "2270580934", "name": "H. Bando"}, {"authorId": "2276046518", "name": "T. Yoshino"}], "url": "https://www.semanticscholar.org/paper/95eea64578438be854c2e6f1fc5658b923eb0f1d", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "94026e01a9aea145c89684e9f81fafa42adf2b0f", "title": "Toxicity and Efficacy of Local Ablative, Image-guided Radiotherapy in Gallium-68 Prostate-specific Membrane Antigen Targeted Positron Emission Tomography-staged, Castration-sensitive Oligometastatic Prostate Cancer: The OLI-P Phase 2 Clinical Trial.", "abstract": "BACKGROUND\nLocal ablative radiotherapy (aRT) of oligometastatic prostate cancer (PCa) is very promising and has become a focus of current clinical research.\n\n\nOBJECTIVE\nWe hypothesize that aRT is safe and effective in gallium-68 prostate-specific membrane antigen targeted positron emission tomography (PSMA-PET)-staged oligometastatic PCa patients.\n\n\nDESIGN, SETTING, AND PARTICIPANTS\nA nonrandomized, prospective, investigator-initiated phase 2 trial recruited patients with oligometastatic PCa (five or fewer lymph node or osseous metastases) after local curative therapy, without significant comorbidity and androgen deprivation therapy (ADT), at two German centers from 2014 to 2018.\n\n\nINTERVENTION\nAll PSMA-PET-positive metastases were treated with aRT. No systemic therapy was initiated.\n\n\nOUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS\nThe primary endpoint was treatment-related toxicity (grade ≥2) 24 mo after aRT. A one-sided single-sample test of proportions was planned to test whether the endpoint occurs in <15% of the patients. Key secondary endpoints were time to progression of prostate-specific antigen (PSA) and time to ADT, which were associated with potential prognostic factors by Cox regression.\n\n\nRESULTS AND LIMITATIONS\nOf 72 patients, 63 received aRT (13% dropout rate). The median follow-up was 37.2 mo. No treatment-related grade ≥2 toxicity was observed 2 yr after treatment. The median time to PSA progression and time to ADT were 13.2 and 20.6 mo, respectively. Of the patients, 21.4% were free of PSA progression after 3 yr.\n\n\nCONCLUSIONS\nIt was observed that aRT is safe, and midterm PSA progression and ADT-free time were achieved in one of five patients. Randomized clinical trials are indicated to further evaluate the option of delaying ADT in selected patients.\n\n\nPATIENT SUMMARY\nIn this clinical trial, 63 patients with up to five metastases of prostate cancer without androgen deprivation therapy were included. We showed that local ablative radiotherapy is safe and that one in five patients had no recurrent prostate-specific antigen value after 3 yr. Local ablative radiotherapy might be an option to avoid systemic therapy in selected patients.", "year": 2021, "publicationDate": "2021-11-01", "publicationTypes": ["JournalArticle"], "venue": "European Urology Oncology", "journal": {"name": "European urology oncology"}, "citationCount": 35, "referenceCount": 31, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S258893112100184X/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "35223969", "name": "T. Hölscher"}, {"authorId": "2053679324", "name": "M. Baumann"}, {"authorId": "3205319", "name": "J. Kotzerke"}, {"authorId": "2922388", "name": "K. Zöphel"}, {"authorId": "39472329", "name": "F. Paulsen"}, {"authorId": "73841288", "name": "A. Müller"}, {"authorId": "2838825", "name": "D. Zips"}, {"authorId": "5651853", "name": "L. Koi"}, {"authorId": "1405881667", "name": "C. Thomas"}, {"authorId": "6284311", "name": "S. Löck"}, {"authorId": "145415677", "name": "M. Krause"}, {"authorId": "2055806883", "name": "M. Wirth"}, {"authorId": "12558422", "name": "F. Lohaus"}], "url": "https://www.semanticscholar.org/paper/94026e01a9aea145c89684e9f81fafa42adf2b0f", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "ef0fba81b7e88d536cabd38ef37a65d1ee8deb78", "title": "Systematic Next Generation Sequencing is feasible in clinical practice and identifies opportunities for targeted therapy in women with uterine cancer: Results from a prospective cohort study.", "abstract": "BACKGROUND\nBoth incidence and mortality of uterine cancer are on the rise and mortality is higher for African American women. The aim of our study was to evaluate how Next Generation Sequencing (NGS) may facilitate identification of and intervention for treatment disparities when integrated into clinical workflows.\n\n\nRESULTS\nOur cohort included 159 uterine cancer patients with recurrent/progressive and newly diagnosed advanced stage and/or high-risk histology. The most common tumor histological subtypes included EEC (n = 67), SEC (n = 34), UCS (n = 20), and mixed (n = 14). Black patients were most likely to present with aggressive histology: (SEC, 34.0%) and carcinosarcoma (UCS, 14.0%). The four most common mutations across all subtypes were TP53, PIK3CA, PTEN, and ARID1A. There was racial disparity between Black versus non-Black patients who were initiated on targeted therapy (28.2% vs. 38.2%, respectively) and clinical trial (15% vs. 22.6%, respectively). Compared to non-Black patients, Black patients had a significantly higher percentage TP53 mutations (p < 0.05) and a significantly lower percentage ARID1A mutations (p < 0.05).\n\n\nCONCLUSIONS\nNGS for uterine malignancies provides actionable information for targetable mutations and/or clinical trial enrollment in most patients; further investigation is necessary to identify potentially modifiable factors contributing to current disparities that may improve targeted therapy uptake and clinical trial participation.", "year": 2021, "publicationDate": "2021-08-06", "publicationTypes": ["JournalArticle"], "venue": "Gynecologic Oncology", "journal": {"name": "Gynecologic oncology"}, "citationCount": 14, "referenceCount": 35, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://manuscript.elsevier.com/S0090825821005795/pdf/S0090825821005795.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "50215459", "name": "R. Arend"}, {"authorId": "1596719700", "name": "N. Goel"}, {"authorId": "12488777", "name": "B. Roane"}, {"authorId": "88738884", "name": "M. Foxall"}, {"authorId": "51442754", "name": "J. Dholakia"}, {"authorId": "48838912", "name": "A. Londoño"}, {"authorId": "1575124688", "name": "J. Wall"}, {"authorId": "6406133", "name": "C. Leath"}, {"authorId": "1733976", "name": "W. Huh"}], "url": "https://www.semanticscholar.org/paper/ef0fba81b7e88d536cabd38ef37a65d1ee8deb78", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "e33bdbb505d3f71217347254b79241ca2dc91818", "title": "Durvalumab, tremelimumab alone or in combination with low-dose or hypofractionated targeted radiotherapy in metastatic non-small cell lung cancer refractory to prior PD(L)-1 therapy: a multicentre, open-label, randomised, phase 2 trial", "abstract": "Summary Background Patients with PD(L)-1 therapy resistant non-small cell lung cancer (NSCLC) have poor outcomes. Studies suggest radiotherapy may enhance anti-tumor immunity. Therefore, we investigated combined PD-L1 (durvalumab) and CTLA-4 inhibition (tremelimumab) alone or combined with radiation. Methods This multicentre, randomised, open-label phase 2 NCI Experimental Therapeutics Clinical Trials Network trial was conducted at 18 U.S. sites. Patients aged >=18 years with metastatic NSCLC, Eastern Cooperative Oncology Group performance status of 0 or 1, and progression during previous PD(L)-1 therapy were randomised (1:1:1) using a permuted block scheme, without stratification to durvalumab/tremelimumab (1500mg/75mg every 4 weeks, 4 cycles, intravenous) alone (noRT) or with low-dose (LDFRT) or hypofractionated (HFRT) radiotherapy followed by durvalumab until 52 weeks or progression. The primary endpoint was the rate of complete/partial response in patients who initiated study treatment. The trial is registered with ClinicalTrials.gov, NCT02888743, and is now complete. Findings 90 patients were randomised and 78 patients treated between 24 August 2017 and 29 March 2019. Median follow up was 12.4 months (IQR 7.8-15.1). There were no differences in response rates between the noRT arm (3 [11.5%] of 26, 90% CI 1.2-21.8) and the LDFRT (2 [7.7%] of 26, 0-16.3, p=0.64) or HFRT (3 [11.5%] of 26, 90% CI 1.2-21.8, p=0.99) arms. The most common grade 3-4 adverse event was dyspnea (2 [8%] of 26 NoRT, 3 [11%] LDFRT, and 3 [11%] HFRT). Serious adverse events occurred in 4 (15%, NoRT), 8 (31%, LDFRT) and 3 (12%, HFRT) patients. There was 1 grade-5 respiratory failure potentially related to therapy (LDFRT arm). Interpretation Radiation should not be used to increase response to PD-L1/CTLA-4 inhibition in PD(L)-1-resistant NSCLC patients. However, PD-L1/CTLA-4 therapy could be a treatment option for some patients. Future studies should refine predictive biomarkers in this setting. Funding: US National Institutes of Health, Dana-Farber Cancer Institute", "year": 2022, "publicationDate": "2022-01-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet Oncology", "journal": {"name": "The Lancet. Oncology", "pages": "279 - 291", "volume": "23"}, "citationCount": 187, "referenceCount": 29, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "http://manuscript.elsevier.com/S1470204521006586/pdf/S1470204521006586.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2555325", "name": "J. Schoenfeld"}, {"authorId": "1398497611", "name": "A. Giobbie-Hurder"}, {"authorId": "8171645", "name": "S. Ranasinghe"}, {"authorId": "2048173041", "name": "Katrina Z Kao"}, {"authorId": "3931691", "name": "Ana Lako"}, {"authorId": "39909358", "name": "J. Tsuji"}, {"authorId": "2152800746", "name": "Yang Liu"}, {"authorId": "80275048", "name": "Ryan C Brennick"}, {"authorId": "3532201", "name": "R. Gentzler"}, {"authorId": "153897222", "name": "Carrie Lee"}, {"authorId": "6810358", "name": "J. Hubbard"}, {"authorId": "2313707", "name": "S. Arnold"}, {"authorId": "5192828", "name": "J. Abbruzzese"}, {"authorId": "2877244", "name": "S. Jabbour"}, {"authorId": "5942565", "name": "N. Uboha"}, {"authorId": "3606716", "name": "K. Stephans"}, {"authorId": "48912880", "name": "Jennifer M. Johnson"}, {"authorId": "48415613", "name": "Haeseong Park"}, {"authorId": "3793224", "name": "L. Villaruz"}, {"authorId": "66478424", "name": "E. Sharon"}, {"authorId": "36713986", "name": "H. Streicher"}, {"authorId": "144658212", "name": "Mansoor M Ahmed"}, {"authorId": "2075053085", "name": "Hayley Lyon"}, {"authorId": "2150118511", "name": "Carrie Cibuskis"}, {"authorId": "3101872", "name": "N. Lennon"}, {"authorId": "2053756609", "name": "Aashna Jhaveri"}, {"authorId": "39161835", "name": "Lin Yang"}, {"authorId": "15909912", "name": "Jennifer Altreuter"}, {"authorId": "2147162190", "name": "L. Gunasti"}, {"authorId": "1822363", "name": "J. Weirather"}, {"authorId": "1996033", "name": "R. Mak"}, {"authorId": "2566925", "name": "M. Awad"}, {"authorId": "3977072", "name": "S. Rodig"}, {"authorId": "1390823268", "name": "Helen X. Chen"}, {"authorId": "1920712896", "name": "Catherine J. Wu"}, {"authorId": "2239232", "name": "A. Monjazeb"}, {"authorId": "6354569", "name": "F. Hodi"}], "url": "https://www.semanticscholar.org/paper/e33bdbb505d3f71217347254b79241ca2dc91818", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "7da50b3653d44d03cf0afdaeb7723bc8a31d212a", "title": "The role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial", "abstract": "Background The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) remains unclear in the immuno-oncology (IO) era. The results of two randomized trials, CARMENA and SURTIME, questioned the role and timing of CN. However, despite the latest advances in the systemic treatment of mRCC, previous trials have only used targeted therapy, and no studies have fully investigated the role of CN in immune checkpoint inhibitor (CPI) settings, and there is an urgent need for future studies to better define the role and timing of CN. Methods This study is an open-label, multi-center, parallel, prospective, randomized, interventional clinical study to evaluate the efficacy of CN in combination with CPIs in mRCC patients with International mRCC Database Consortium (IMDC) intermediate- and poor-risk. Synchronous mRCC patients with ≤ 3 IMDC risk features will be randomly allocated to three groups (1, upfront CN; 2, deferred CN; and 3, systemic therapy [ST] only). For ST, the nivolumab plus ipilimumab combination regimen, one of the standard regimens for intermediate- and poor-risk mRCC, is chosen. The primary endpoint is overall survival. The secondary endpoints are progression-free survival, objective response rate, number of participants with treatment-related adverse events, and number of participants with surgical morbidity. We will analyze the genetic mutation profiles of the tumor tissue, circulating tumor DNA, urine tumor DNA, and tumor-infiltrating lymphocytes. The gut and urine microbial communities will be analyzed. The study will begin in 2022 and will enroll 55 patients. Discussion This study is one of the few prospective randomized trials to evaluate the benefit of CN in the treatment of synchronous mRCC in the IO era. The SEVURO-CN trial will help identify the role and timing of CN, thereby rediscovering the value of CN. Trial registration ClinicalTrials.gov, NCT05753839. Registered on 3 March 2023.", "year": 2024, "publicationDate": "2024-02-01", "publicationTypes": ["JournalArticle"], "venue": "Trials", "journal": {"name": "Trials", "volume": "25"}, "citationCount": 12, "referenceCount": 22, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1186/s13063-024-08234-2", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2952569", "name": "J. Park"}, {"authorId": "2116400304", "name": "Jongchan Kim"}, {"authorId": "2184379062", "name": "Jinhyung Jeon"}, {"authorId": "2108780019", "name": "Jongsoo Lee"}, {"authorId": "28058584", "name": "W. S. Jang"}, {"authorId": "2169592900", "name": "Seung Hwan Lee"}, {"authorId": "6092729", "name": "W. Han"}, {"authorId": "2247910453", "name": "Y. Choi"}, {"authorId": "6928948", "name": "K. Koo"}, {"authorId": "2256949234", "name": "K. Cho"}, {"authorId": "2272989547", "name": "B. H. Chung"}, {"authorId": "2261173058", "name": "Won Sik Ham"}], "url": "https://www.semanticscholar.org/paper/7da50b3653d44d03cf0afdaeb7723bc8a31d212a", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "090e3ee1c3831daf6219919e7a33455aa4faaaa5", "title": "Targeting Inhibitor of Apoptosis Proteins to Overcome Chemotherapy Resistance—A Marriage between Targeted Therapy and Cytotoxic Chemotherapy", "abstract": "Precision oncology is the ultimate goal of cancer treatment, i.e., to treat cancer and only cancer, leaving all the remaining cells and tissues as intact as possible. Classical chemotherapy and radiotherapy, however, are still effective in many patients with cancer by effectively inducing apoptosis of cancer cells. Cancer cells might resist apoptosis via the anti-apoptotic effects of the inhibitor of apoptosis proteins. Recently, the inhibitors of those proteins have been developed with the goal of enhancing the cytotoxic effects of chemotherapy and radiotherapy, and one of them, xevinapant, has already demonstrated effectiveness in a phase II clinical trial. This class of drugs represents an example of synergism between classical cytotoxic chemo- and radiotherapy and new targeted therapy.", "year": 2023, "publicationDate": "2023-08-29", "publicationTypes": ["Review", "JournalArticle"], "venue": "International Journal of Molecular Sciences", "journal": {"name": "International Journal of Molecular Sciences", "volume": "24"}, "citationCount": 13, "referenceCount": 49, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/1422-0067/24/17/13385/pdf?version=1693299558", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2308381471", "name": "Tiago Barroso"}, {"authorId": "1753265390", "name": "C. Melo-Alvim"}, {"authorId": "36447556", "name": "L. Ribeiro"}, {"authorId": "4053685", "name": "S. Casimiro"}, {"authorId": "2087040358", "name": "L. Costa"}], "url": "https://www.semanticscholar.org/paper/090e3ee1c3831daf6219919e7a33455aa4faaaa5", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "25fb7cf82ab4593582080d2fad065d02251a7f90", "title": "The role of molecular biomarkers in recurrent glioblastoma trials: an assessment of the current trial landscape of genome-driven oncology", "abstract": "For glioblastoma patients, the efficacy-targeted therapy is limited to date. Most of the molecular therapies previously studied are lacking efficacy in this population. More trials are needed to study the actual actionability of biomarkers in (recurrent) glioblastoma. This study aimed to assess the current clinical trial landscape to assess the role of molecular biomarkers in trials on recurrent glioblastoma treatment. The database ClinicalTrials.gov was used to identify not yet completed clinical trials on recurrent glioblastoma in adults. Recruiting studies were assessed to investigate the role of molecular criteria, which were retrieved as detailed as possible. Primary outcome was molecular criteria used as selection criteria for study participation. Next to this, details on moment and method of testing, and targets and drugs studied, were collected. In 76% (181/237) of the included studies, molecular criteria were not included in the study design. Of the remaining 56 studies, at least one specific genomic alteration as selection criterium for study participation was required in 33 (59%) studies. Alterations in EGFR, CDKN2A/B or C, CDK4/6, and RB were most frequently investigated, as were the corresponding drugs abemaciclib and ribociclib. Of the immunotherapies, CAR-T therapies were the most frequently studied therapies. Previously, genomics studies have revealed the presence of potentially actionable alterations in glioblastoma. Our study shows that the potential efficacy of targeted treatment is currently not translated into genome-driven trials in patients with recurrent glioblastoma. An intensification of genome-driven trials might help in providing evidence for (in)efficacy of targeted treatments.", "year": 2024, "publicationDate": "2024-09-24", "publicationTypes": ["JournalArticle"], "venue": "Medical Oncology", "journal": {"name": "Medical Oncology (Northwood, London, England)", "volume": "41"}, "citationCount": 4, "referenceCount": 22, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1007/s12032-024-02501-7", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}], "authors": [{"authorId": "2104699455", "name": "M. P. van Opijnen"}, {"authorId": "2238765041", "name": "F. de Vos"}, {"authorId": "2237843023", "name": "Edwin Cuppen"}, {"authorId": "2253611602", "name": "M. Geurts"}, {"authorId": "2238730222", "name": "S. Maas"}, {"authorId": "152995575", "name": "M. Broekman"}], "url": "https://www.semanticscholar.org/paper/25fb7cf82ab4593582080d2fad065d02251a7f90", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "75897730c1da1ab32bb7339c8e51ca8f73390adf", "title": "Targeted therapy in advanced non-small cell lung cancer: current advances and future trends", "abstract": "Lung cancer remains the leading cause of cancer-related mortality in both men and women in the US and worldwide. Non-small cell lung cancer is the most common variety accounting for 84% of the cases. For a subset of patients with actionable mutations, targeted therapy continues to provide durable responses. Advances in molecular and immunohistochemical techniques have made it possible to usher lung cancer into the era of personalized medicine, with the patient getting individualized treatment based on these markers. This review summarizes the recent advances in advanced NSCLC targeted therapy, focusing on first-in-human and early phase I/II clinical trials in patients with advanced disease. We have divided our discussion into different topics based on these agents' mechanisms of action. This article is aimed to be the most current review of available and upcoming targeted NSCLC treatment options. We will also summarize the currently available phase I/II clinical trial for NSCLC patients at the end of each section.", "year": 2021, "publicationDate": "2021-07-08", "publicationTypes": ["Review", "JournalArticle"], "venue": "Journal of Hematology & Oncology", "journal": {"name": "Journal of Hematology & Oncology", "volume": "14"}, "citationCount": 219, "referenceCount": 124, "influentialCitationCount": 10, "isOpenAccess": true, "openAccessPdfUrl": "https://jhoonline.biomedcentral.com/counter/pdf/10.1186/s13045-021-01121-2", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "46981261", "name": "U. Majeed"}, {"authorId": "8673125", "name": "R. Manochakian"}, {"authorId": "51236053", "name": "Yujie Zhao"}, {"authorId": "14824716", "name": "Y. Lou"}], "url": "https://www.semanticscholar.org/paper/75897730c1da1ab32bb7339c8e51ca8f73390adf", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "19bd05470553c6c168436a8017cc3ea4da5888fe", "title": "The role of immunotherapy and targeted therapy in the multimodal therapy for resectable lung cancer", "abstract": "As the immunotherapeutic milieu in resectable nonsmall cell lung cancer continues to evolve, the field of thoracic oncology actively moves towards better patient selection based on biomarkers and oncogenic drivers. In this article, we review the current standard of oncologic care in this population and discuss the ongoing phase III clinical trials investigating the use of immunotherapy or targeted therapy in the perioperative period. We also discuss genotyping initiatives, biomarkers, and trial endpoints.", "year": 2023, "publicationDate": "2023-01-11", "publicationTypes": ["Review", "JournalArticle"], "venue": "Journal of Surgical Oncology", "journal": {"name": "Journal of Surgical Oncology", "pages": "275 - 281", "volume": "127"}, "citationCount": 4, "referenceCount": 32, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "134508392", "name": "Nathaniel Deboever"}, {"authorId": "2199922756", "name": "M. Eisenberg"}, {"authorId": "3919736", "name": "A. Chidi"}, {"authorId": "7216563", "name": "B. Sepesi"}], "url": "https://www.semanticscholar.org/paper/19bd05470553c6c168436a8017cc3ea4da5888fe", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "8afa2f763ef70d992464fa2efd8605bf54d794a9", "title": "Impact of a Clinical Genomics Program on Trial Accrual for Targeted Treatments: Practical Approach Overcoming Barriers to Accrual for Underserved Patients.", "abstract": "PURPOSE\nClinical trials of novel and targeted agents increasingly require biomarkers for eligibility. Precision oncology continues to evolve, but challenges hamper broad use of molecular profiling (MP) that could increase the number of patients benefiting from targeted therapy. We implemented an integrated clinical genomics program (CGP), including a virtual Molecular Tumor Board (MTB), and examined its impact on MP use and impact on clinical trial accrual in a multisite regional-based cancer system with an emphasis on effects for isolated clinicians.\n\n\nMETHODS\nWe assessed MP and MTB use from 2010 to 2020 by practice location, physician experience, and patient characteristics. Use of MTB-recommended treatments was assessed. Clinical trial enrollment was evaluated for patients with MP versus MP and MTB review.\n\n\nRESULTS\nAfter CGP implementation, the number of physicians using MP and the number of MP tests increased ≥ 10-fold. The proportion of Hispanic patients with MP was the same as that in the system (both 2%) with marginal differences observed in the proportion of African Americans tested compared with the system population (16% v 19%). Physicians followed MTB treatment recommendations in 74% of cases. Rapid clinical decline was the most common reason why physicians did not follow MTB recommendations. Clinical trial accrual was 15% (669 of 4,459) for patients with MP alone and 28% (94 of 334) with both MP and MTB review. Clinical trial availability and patient out-of-pocket costs affected MP use.\n\n\nCONCLUSION\nIntegrating CGP into clinical workflow with decision support tools, trial matching, and management of patient costs led to increased use of MP by physicians with all levels of experience, enhanced clinical trial accrual, and has the potential to reduce disparities in MP.", "year": 2022, "publicationDate": "2022-07-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "JCO Clinical Cancer Informatics", "journal": {"name": "JCO clinical cancer informatics", "pages": "\n          e2200011\n        ", "volume": "6"}, "citationCount": 15, "referenceCount": 25, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://ascopubs.org/doi/pdfdirect/10.1200/CCI.22.00011?role=tab", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "9926397", "name": "C. Farhangfar"}, {"authorId": "82719605", "name": "G. Scarola"}, {"authorId": "122078357", "name": "V. Morris"}, {"authorId": "5153725", "name": "F. Farhangfar"}, {"authorId": "82620037", "name": "K. Dumas"}, {"authorId": "6105930", "name": "J. Symanowski"}, {"authorId": "2342462044", "name": "Jimmy J. Hwang"}, {"authorId": "10768733", "name": "K. Mileham"}, {"authorId": "5884723", "name": "D. Carrizosa"}, {"authorId": "34965501", "name": "R. Naumann"}, {"authorId": "2442127", "name": "C. Livasy"}, {"authorId": "1932580", "name": "Edward S Kim"}, {"authorId": "52606215", "name": "D. Raghavan"}], "url": "https://www.semanticscholar.org/paper/8afa2f763ef70d992464fa2efd8605bf54d794a9", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "c7756cc404a9fe03362e53b9dcd3edd0203bc549", "title": "Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making.", "abstract": "BACKGROUND\nTargeted gene NGS testing is available through many academic institutions and commercial entities and is increasingly incorporated in practice guidelines for glioblastoma (GBM). This single-center retrospective study aimed to evaluate the clinical utility of incorporating NGS results in the management of GBM patients at a clinical trials-focused academic center.\n\n\nMETHODS\nWe identified 1,011 consecutive adult patients with pathologically confirmed GBM (IDHwt or IDHmut) who had somatic tumor sequencing (Oncopanel, ~500 cancer gene panel) at DFCI from 2013-2019. Clinical records of all IDHwt GBM patients were reviewed to capture clinical trial enrollment and off-label targeted therapy use based on NGS results.\n\n\nRESULTS\nOf the 557 IDHwt GBM patients with sequencing, 182 entered clinical trials at diagnosis (32.7%) and 213 (38.2%) entered after recurrence. Sequencing results for 130 patients (23.3%) were utilized for clinical trial enrollment for either targeted therapy indications (6.9 % upfront and 27.7% at recurrent clinical trials and 3.1% for off-label targeted therapy) or exploratory studies (55.4% upfront and 6.9% recurrent clinical trials). Median overall survival was 20.1 months with no survival difference seen between patients enrolled in clinical trials compared to those who were not, in a post hoc analysis.\n\n\nCONCLUSIONS\nWhile NGS testing has become essential for improved molecular diagnostics, our study illustrates that targeted gene panels remain underutilized for selecting therapy in GBM-IDHwt. Targeted therapy and clinical trial design remain to be improved to help leverage the potential of NGS in clinical care.", "year": 2021, "publicationDate": "2021-12-08", "publicationTypes": ["JournalArticle", "Review"], "venue": "Neuro-Oncology", "journal": {"name": "Neuro-oncology"}, "citationCount": 24, "referenceCount": 38, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://academic.oup.com/neuro-oncology/article-pdf/24/7/1140/44371660/noab282.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1405336337", "name": "M. Lim-Fat"}, {"authorId": "40382102", "name": "G. Youssef"}, {"authorId": "4455563", "name": "M. Touat"}, {"authorId": "6251280", "name": "J. Iorgulescu"}, {"authorId": "2044974164", "name": "S. Whorral"}, {"authorId": "2069417281", "name": "M. Allen"}, {"authorId": "144227510", "name": "R. Rahman"}, {"authorId": "51007709", "name": "U. Chukwueke"}, {"authorId": "1401896862", "name": "J. McFaline-Figueroa"}, {"authorId": "1892728", "name": "L. Nayak"}, {"authorId": "32917015", "name": "E. Lee"}, {"authorId": "2070582347", "name": "Tracy T Batchelor"}, {"authorId": "8083287", "name": "O. Arnaout"}, {"authorId": "47378377", "name": "Pierpaolo Peruzzi"}, {"authorId": "2050121397", "name": "E. Chiocca"}, {"authorId": "2648068", "name": "D. Reardon"}, {"authorId": "49115040", "name": "David M. Meredith"}, {"authorId": "48160758", "name": "S. Santagata"}, {"authorId": "2318365", "name": "R. Beroukhim"}, {"authorId": "6559881", "name": "W. Bi"}, {"authorId": "5627829", "name": "K. Ligon"}, {"authorId": "145426034", "name": "P. Wen"}], "url": "https://www.semanticscholar.org/paper/c7756cc404a9fe03362e53b9dcd3edd0203bc549", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "4d312b96a1facbef7b153b220782396ec0954f62", "title": "Molecular Tumor Board–Assisted Care in an Advanced Cancer Population: Results of a Phase II Clinical Trial", "abstract": "PURPOSE Multidisciplinary molecular tumor boards (MTBs) interpret next-generation sequencing reports and help oncologists determine best therapeutic options; however, there is a paucity of data regarding their clinical utility. The purpose of this study was to determine if MTB-directed therapy improves progression-free survival (PFS) over immediately prior therapy in patients with advanced cancer. METHODS This single-arm, prospective phase II clinical trial enrolled patients with advanced cancer with an actionable mutation who received MTB-recommended targeted therapy between January 1, 2017, and October 31, 2020. MTB-recommended both on-label (level 1 evidence) and off-label (evidence levels 2 and 3) therapies. Of the 93 enrolled patients, 43 were treated frontline and 50 received second-line or greater-line therapy. The primary outcome was the probability of patients treated with second-line or greater-line MTB-directed therapy who achieved a PFS ratio ≥ 1.3 (PFS on MTB-directed therapy divided by PFS on the patient's immediately prior therapy). Secondary outcomes included PFS for patients treated frontline and overall survival and adverse effects for the entire study population. RESULTS The most common disease sites were lung (35 of 93, 38%), gynecologic (17 of 93, 18%), GI (16 of 93, 17%), and head and neck (7 of 93, 8%). The Kaplan-Meier estimate of the probability of PFS ratio ≥ 1.3 was 0.59 (95% CI, 0.47 to 0.75) for patients treated with second-line or greater-line MTB-directed therapy. The median PFS was 449 (range 42-1,125) days for patients treated frontline. The median overall survival was 768 (range 22-1,240) days. There were four nontreatment-related deaths. CONCLUSION When treated with MTB-directed therapy, most patients experienced improved PFS compared with immediately prior treatment. MTB-directed targeted therapy may be a strategy to improve outcomes for patients with advanced cancer.", "year": 2022, "publicationDate": "2022-08-01", "publicationTypes": ["JournalArticle"], "venue": "JCO Precision Oncology", "journal": {"name": "JCO Precision Oncology", "volume": "6"}, "citationCount": 24, "referenceCount": 33, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://ascopubs.org/doi/pdfdirect/10.1200/PO.21.00524?role=tab", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2110475366", "name": "Rachel W. Miller"}, {"authorId": "79799456", "name": "M. Hutchcraft"}, {"authorId": "2054553335", "name": "H. Weiss"}, {"authorId": "2131376114", "name": "Jianrong Wu"}, {"authorId": "2144563156", "name": "Chi Wang"}, {"authorId": "2224168", "name": "Jinpeng Liu"}, {"authorId": "5669253", "name": "Rani Jayswal"}, {"authorId": "2167922390", "name": "Mikayla Buchanan"}, {"authorId": "1509096093", "name": "Abigail M. Anderson"}, {"authorId": "40457938", "name": "Derek B. Allison"}, {"authorId": "82772397", "name": "Riham H. El Khouli"}, {"authorId": "2099878804", "name": "Reema A Patel"}, {"authorId": "5305727", "name": "J. Villano"}, {"authorId": "2313707", "name": "S. Arnold"}, {"authorId": "2063104354", "name": "J. Kolesar"}], "url": "https://www.semanticscholar.org/paper/4d312b96a1facbef7b153b220782396ec0954f62", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "ba46805e808ca56b9163cb311be01ef7d415f141", "title": "Pemigatinib: Hot topics behind the first approval of a targeted therapy in cholangiocarcinoma.", "abstract": "Cholangiocarcinoma (CCA) includes a heterogeneous group of malignancies with limited treatment options. Despite recent advances in medical oncology, the prognosis of CCA patients with metastatic disease remains poor, with a median overall survival of less than a year. In the last decade, notable efforts have been made by the CCA medical community in an attempt to improve clinical outcomes of patients, with the development of molecularly targeted therapies in this setting. Among these treatments, the fibroblast growth factor receptor (FGFR) 2 inhibitor pemigatinib has received accelerated approval in April 2020 by the US Food and Drug Administration (FDA) in CCA patients harboring FGFR2 gene fusions or other rearrangements, on the basis of the results of the FIGHT-202 trial, and thus, representing the first molecularly targeted therapy to be approved for the treatment of CCA. However, several issues remain, including the emergence of polyclonal mutations determining resistance to pemigatinib, the identification of biomarkers predictive of response, and the knowledge gaps regarding the role of other FGFR gene aberrations. This review aims to provide an overview of recent development of pemigatinib, especially focusing on the results of the pivotal FIGHT-202 trial, the approval of this FGFR inhibitor, and the future challenges concerning the use of FGFR-directed treatments in CCA patients.", "year": 2021, "publicationDate": "2021-02-18", "publicationTypes": ["Review", "JournalArticle"], "venue": "Cancer Treatment and Research Communications", "journal": {"name": "Cancer treatment and research communications", "pages": "\n          100337\n        ", "volume": "27"}, "citationCount": 78, "referenceCount": 88, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S2468294221000368/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "47411122", "name": "A. Rizzo"}, {"authorId": "1442214926", "name": "A. Ricci"}, {"authorId": "8623613", "name": "G. Brandi"}], "url": "https://www.semanticscholar.org/paper/ba46805e808ca56b9163cb311be01ef7d415f141", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "24e34a9c73968a7b4c2807c8f51e59c8cc5741b9", "title": "Clinical Value of Molecular Targets and FDA-Approved Genome-Targeted Cancer Therapies.", "abstract": "Importance\nThe number of new genome-targeted cancer drugs has increased, offering the possibility of personalized therapy, often at a very high cost.\n\n\nObjective\nTo assess the validity of molecular targets and therapeutic benefits of US Food and Drug Administration-approved genome-targeted cancer drugs based on the outcomes of their corresponding pivotal clinical trials.\n\n\nDesign and Settings\nIn this cohort study, all genome-targeted cancer drugs that were FDA-approved between January 1, 2015, and December 31, 2022, were analyzed. From FDA drug labels and trial reports, key characteristics of pivotal trials were extracted, including the outcomes assessed.\n\n\nMain Outcomes and Measures\nThe strength of evidence supporting molecular targetability was assessed using the European Society for Medical Oncology (ESMO) Scale for Clinical Actionability of Molecular Targets (ESCAT). Clinical benefit for their approved indications was evaluated using the ESMO-Magnitude of Clinical Benefit Scale (ESMO-MCBS). Substantial clinical benefit was defined as a grade of A or B for curative intent and 4 or 5 for noncurative intent. Molecular targets qualifying for ESCAT category level I-A and I-B associated with substantial clinical benefit by ESMO-MCBS were rated as high-benefit genomic-based cancer treatments.\n\n\nResults\nA total of 50 molecular-targeted drugs covering 84 indications were analyzed. Forty-five indications (54%) were approved based on phase 1 or phase 2 pivotal trials, 45 (54%) were supported by single-arm pivotal trials, and 48 (57%) were approved on the basis of subgroup analyses. By each indication, 46 of 84 primary end points (55%) were overall response rate (median [IQR] overall response rate, 57% [40%-69%]; median [IQR] duration of response, 11.1 [9.2-19.8] months). Among the 84 pivotal trials supporting these 84 indications, 38 trials (45%) had I-A ESCAT targetability, and 32 (38%) had I-B targetability. Overall, 24 of 84 trials (29%) demonstrated substantial clinical benefit via ESMO-MCBS. Combining these ratings, 24 of 84 indications (29%) were associated with high-benefit genomic-based cancer treatments.\n\n\nConclusions and Relevance\nThe results of this cohort study demonstrate that among recently approved molecular-targeted cancer therapies, fewer than one-third demonstrated substantial patient benefits at approval. Benefit frameworks such as ESMO-MCBS and ESCAT can help physicians, patients, and payers identify therapies with the greatest clinical potential.", "year": 2024, "publicationDate": "2024-04-04", "publicationTypes": ["JournalArticle"], "venue": "JAMA Oncology", "journal": {"name": "JAMA oncology"}, "citationCount": 21, "referenceCount": 32, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "5038991", "name": "A. Tibau"}, {"authorId": "8140938", "name": "T. Hwang"}, {"authorId": "30923633", "name": "C. Molto"}, {"authorId": "2261007378", "name": "J. Avorn"}, {"authorId": "2261005115", "name": "A. Kesselheim"}], "url": "https://www.semanticscholar.org/paper/24e34a9c73968a7b4c2807c8f51e59c8cc5741b9", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "4292638b7448fc48e9d528ee28b5b2f7deb5c409", "title": "Status of PSMA-targeted radioligand therapy in prostate cancer: current data and future trials", "abstract": "Metastatic prostate cancer continues to be an incurable disease. Despite all the novel therapies approved in the past two decades, overall patient outcomes remain relatively poor, and these patients die on a regular basis. Clearly, improvements in current therapies are needed. Prostate-specific membrane antigen (PSMA) is a target for prostate cancer given its increased expression on the surface of the prostate cancer cells. PSMA small molecule binders include PSMA-617 and PSMA-I&T and monoclonal antibodies such as J591. These agents have been linked to different radionuclides including beta-emitters such as lutetium-177 and alpha-emitters such as actinium-225. The only regulatory-approved PSMA-targeted radioligand therapy (PSMA-RLT) to date is lutetium-177–PSMA-617 in the setting of PSMA-positive metastatic castration-resistant prostate cancer that has failed androgen receptor pathway inhibitors and taxane chemotherapy. This approval was based on the phase III VISION trial. Many other clinical trials are evaluating PSMA-RLT in various settings. Both monotherapy and combination studies are underway. This article summarizes pertinent data from recent studies and provides an overview of human clinical trials in progress. The field of PSMA-RLT is rapidly evolving, and this therapeutic approach will likely play an increasingly important role in the years to come.", "year": 2023, "publicationDate": "2023-01-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "Therapeutic Advances in Medical Oncology", "journal": {"name": "Therapeutic Advances in Medical Oncology", "volume": "15"}, "citationCount": 84, "referenceCount": 48, "influentialCitationCount": 5, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1177/17588359231157632", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1994688447", "name": "Albert Jang"}, {"authorId": "2276629040", "name": "A. Kendi"}, {"authorId": "65914059", "name": "O. Sartor"}], "url": "https://www.semanticscholar.org/paper/4292638b7448fc48e9d528ee28b5b2f7deb5c409", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "04b88f944f216acb4667ed10001d612e31568a8f", "title": "Targeted therapy moves to earlier stages of non-small-cell lung cancer: emerging evidence, controversies and future challenges.", "abstract": "Lung cancer continues to be the leading cause of cancer mortality and a serious health problem despite the numerous advances made in the last decade and the rapid advance of research in this field. In recent years, there has been a decrease in mortality from lung cancer coinciding with the approval times of targeted therapy. To date, targeted therapy has been used in the context of advanced disease in clinical practice, with great benefits in survival and quality of life. The next step will be to incorporate targeted therapy into the treatment of earlier stages of non-small-cell lung cancer, and there is already a randomized trial showing a disease-free survival benefit. However, there are many questions that need to be resolved first. In the present review, the authors discuss the findings of published reports and ongoing clinical trials assessing the role of targeted therapies in nonmetastatic disease.", "year": 2021, "publicationDate": "2021-08-02", "publicationTypes": ["JournalArticle", "Review"], "venue": "Future Oncology", "journal": {"name": "Future oncology"}, "citationCount": 18, "referenceCount": 36, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "1401859340", "name": "X. Mielgo-Rubio"}, {"authorId": "2110743521", "name": "Margarita Martín"}, {"authorId": "40061659", "name": "J. Remon"}, {"authorId": "2906354", "name": "O. Higuera"}, {"authorId": "145163676", "name": "V. Calvo"}, {"authorId": "6148089", "name": "J. Jarabo"}, {"authorId": "145200416", "name": "E. Conde"}, {"authorId": "144352464", "name": "J. Luna"}, {"authorId": "5741118", "name": "M. Provencio"}, {"authorId": "1995688", "name": "J. de Castro"}, {"authorId": "1396013317", "name": "F. López-Rios"}, {"authorId": "1403799423", "name": "F. Hernando-Trancho"}, {"authorId": "5238470", "name": "F. Couñago"}], "url": "https://www.semanticscholar.org/paper/04b88f944f216acb4667ed10001d612e31568a8f", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "2909af9505c7e68e77fb2c6383b66ec3c30bd537", "title": "Preliminary efficacy and safety of Relmacabtagene autoleucel (Carteyva) in adults with relapsed/refractory follicular lymphoma in China: A phase I/II clinical trial", "abstract": "To the Editor: Follicular lymphoma (FL) is an indolent B cell lymphoproliferative disorder and the second most common type of non-Hodgkin lymphoma. The recent development of chimeric antigen receptor (CAR)-T cell therapy has provided a novel and effective treatment strategy for patients with relapsed/refractory (r/r) FL. Relmacabtagene autoleucel (relma-cel, also known as Carteyva and JWCAR029) is a secondgeneration CD19-targeted CAR-T cell with a 4-1BB co-stimulatory domain that was developed in China. A single-arm, multicenter study in China reported that relma-cel achieved a 3-month ORR of 60.3% in patients with r/r diffuse large B-cell lymphoma (LBCL), and relma-cel is approved by the National Medical Products Administration (NMPA) for the treatment of r/r LBCL. However, the efficacy, safety and optimal dose of relma-cel in patients with r/r FL has yet to be determined. This study analyzed the r/r FL cohort in dose expansion and subjects in dose escalation administrated with either 100 10 or 150 10 CAR-T cells of the RELIANCE trial (NCT04089215), which enrolled patients with LBCL or FL at 6 tertiary hospitals in China. The inclusion criteria of r/r FL cohort were as follows: (1) age ≥ 18 yearsold; (2) grade 1, 2 or 3a FL confirmed histologically within 6 months; (3) treated with anthracyclines and rituximab (or other CD20-targeted therapies); (4) primary r/r disease within 24 months after at least two lines of therapy or autologous hematopoietic stem cell transplantation; and (5) Eastern Cooperative Oncology Group performance status (ECOG PS) score of 0–1. Full details of the inclusion and exclusion criteria are provided in Supplementary Methods. All subjects underwent leukapheresis for relma-cel preparation (Figure S1A). Bridging therapy including low-dose chemotherapy or targeted therapy was allowed after leukapheresis, and should be completed 7 days before lymphodepletion chemotherapy. The 3-day lymphodepletion chemotherapy regimen (fludarabine 25 mg/m/day plus cyclophosphamide 250 mg/m/day) was completed 2–7 days before relma-cel infusion. Patients received relma-cel at a fixed dose of either 100 10 CAR-T cells or 150 10 CAR-T cells. Dose adjustments were not generally permitted, and any investigator-agreed adjustment was documented. The primary endpoint of the study was complete response rate (CRR) at 3 months assessed by investigator. Other endpoints are presented in the Supplementary Methods. Based on the primary endpoint and under the null hypothesis assumption of 3-month CRR ≤35% for standard therapy in this setting and an alternative hypothesis assumption of 70% 3-month CRR, with the sample size of 26 patients, this study has 94% power and one-sided α of 0.025. Statistical methods are provided in the Supplementary Methods. Among 30 patients with r/r FL screened for enrollment, 24 patients were treated with relma-cel and included in this study. An additional 4 patients were included from the phase I study. Thus, the final analysis included a total of 28 patients with r/r FL (Figure S1B), among which 9 (32.1%) received bridging therapies. No patient had complete response (CR) following bridging therapy before lymphodepleting chemotherapy. Sixteen patients received 100 10 CAR-T cells, and 12 patients received 150 10 CAR-T cells. The median time from leukapheresis to relma-cel infusion was 34 (range: 24–79) days. One patient treated with relma-cel was diagnosed as a second malignancy (gastric adenocarcinoma). The patient was excluded from the efficacy analysis (n = 27), but included in the safety analysis (n = 28). The median age of the 28 patients was 54 (range: 36–71) years. The baseline characteristics were presented in Table S1. The data cutoff date was December 17, 2021. Among 27 patients in the efficacy analysis, the investigatorassessed 3-month CRR was 85.2% (95% confidence interval [CI]: 66.3%–95.8%) (Figure 1A). The independent review committee (IRC)-assessed 3-month CRR was 81.5% (95% CI: 61.9%–93.7%) and the investigator-assessed 3-month overall response rate (ORR) was 100.0% (95% CI: 87.2%–100.0%) in the entire cohort (Table S2). The investigator-assessed 1-, 6-month and best CRR was 66.7% (95% CI: 46.0%–83.5%), 77.8% (95% CI: 57.7%–91.4%) and 92.9% (95% CI: 76.5%–99.1%), respectively for all patients in the efficacy analysis (Table S2). The time to response was 0.89 (range: 0.76–0.95) month. Among 25 patients with complete response as best response, the time to CR was 0.95 (range: 0.76–12.02) month. The 3-month ORR was 100% in all subgroups and the 3-month CRR was above 60.0% in all subgroups (Figure 1B). With a median follow-up time of 11.7 (range: 5.4–24.7) months, the median duration of response and median progression-free survival were not reached in the overall population or in either of the two dose groups (Figure 1C). No patients died during follow-up. The incidence of treatment-emergent adverse events (TEAEs) was 96.4% in all 28 patients, 93.8% in the 100 10 dose group and 100.0% in the 150 10 dose group (Table S3). The most common TEAEs were leukopenia (78.6%). The incidence of grade ≥3 TEAEs was 64.3% in the entire cohort. The most common grade ≥3 TEAEs were neutropenia (39.3%). The incidence of relma-cel-related Received: 17 June 2022 Revised: 24 August 2022 Accepted: 26 August 2022", "year": 2022, "publicationDate": "2022-09-01", "publicationTypes": ["LettersAndComments", "Review"], "venue": "American journal of hematology/oncology", "journal": {"name": "American Journal of Hematology", "volume": "97"}, "citationCount": 6, "referenceCount": 6, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "4058003", "name": "Z. Ying"}, {"authorId": "2427068", "name": "D. Zou"}, {"authorId": "145394511", "name": "Haiyan Yang"}, {"authorId": "7162138", "name": "Jianqiu Wu"}, {"authorId": "48302192", "name": "Ye Guo"}, {"authorId": "122009199", "name": "Wenyu Li"}, {"authorId": "2146673500", "name": "Hui Liu"}, {"authorId": "2183736783", "name": "Chris Wang"}, {"authorId": "31389463", "name": "Laura Ma"}, {"authorId": "98726726", "name": "Su Yang"}, {"authorId": "15717771", "name": "Zisong Zhou"}, {"authorId": "2167994385", "name": "Yun Qin"}, {"authorId": "2166603979", "name": "Yuqin Song"}, {"authorId": "48566672", "name": "Jun Zhu"}], "url": "https://www.semanticscholar.org/paper/2909af9505c7e68e77fb2c6383b66ec3c30bd537", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "6f0671324cef8477205bb5abc1eab07766464cb7", "title": "NRG-BR002: A phase IIR/III trial of standard of care systemic therapy with or without stereotactic body radiotherapy (SBRT) and/or surgical resection (SR) for newly oligometastatic breast cancer (NCT02364557).", "abstract": "1007 Background: Prospective and retrospective studies of patients (pts) with oligometastatic (OM) disease have supported that metastases (mets) directed treatment (MDT) with SBRT or SR in addition to standard of care systemic therapy (SOC ST) can improve progression-free (PFS) and overall survival (OS) compared with SOC ST alone. However, randomized evidence in oligometastatic breast cancer (OMBC) are lacking. NRG-BR002, a randomized Phase IIR/III trial, sought to determine the efficacy of SOC ST + MDT (SBRT or SR) as first line treatment of OMBC. Methods: OMBC pts with ≤ 4 extracranial mets on standard imaging with controlled primary disease were eligible if on first line SOC ST for ≤ 12 months without progression. Pts were randomized (1:1) to ARM 1 – SOC ST (mainly chemotherapy, endocrine therapy, anti-HER2) or ARM 2 – SOC ST with MDT of all mets. Stratification included mets number (1 vs > 1), ER/PR and Her2 status, and chemotherapy use. Phase IIR targeted sample size was 128 total/116 eligible pts, for 92% power and 1-sided significance level = 0.15 to determine if adding MDT shows a signal for improved PFS (hazard ratio [HR] = 0.55, corresponding to median PFS (mPFS) from 10.5 to 19 months), in order to continue to the full phase III trial for OS. PFS and OS were estimated by Kaplan-Meier and arms compared with log-rank. Results: 125 of the 129 pts randomized were eligible (ARM 1 = 65, ARM 2 = 60). Key characteristics included median age 54, 79% ER+ or PR+/HER2-, 13% HER2+, 8% triple negative. 60% had 1 metastasis and 20% presented synchronously with primary disease. Following randomization, systemic therapy was delivered to 95% in ARM 1 and 93% in ARM 2; ablation: SBRT 93%, SR 2%, and 5% none. The median follow-up was 30 mo. The mPFS (70% CI) in ARM 1 was 23 mo (18, 29) and 19.5 mo (17, 36) in ARM 2; 24 and 36-mo PFS (70% CI) for ARM 1 were 45.7% (38.9, 52.5) and 32.8% (26.0, 39.5) compared with 46.8 (39.2, 54.3) and 38.1 (29.7, 46.6) in ARM 2; HR (70% CI): 0.92 (0.71, 1.17); and 1-sided log-rank p = 0.36. As PFS did not show signal, OS reporting is included: median OS was not reached in either arm; 36-mo OS (95% CI) in ARM 1 71.8% (58.9, 84.7) and ARM 2 68.9% (55.1, 82.6; 2-sided log-rank p = 0.54). Analysis of first failure showed new mets outside index area (Arm 1) /RT field (Arm 2) developed similarly in both arms at 40%. There were fewer new mets inside treated/index area for Arm 2 6.7% vs ARM 1 29.2%, respectively. There were no grade 5 treatment-related adverse events (AEs), 1 grade 4 AE in ARM 1, and 9.7% and 5.3% grade 3 AEs in ARMS 1 and 2, respectively. Circulating tumor cell counts (0 vs ≥1) at baseline were similar in both arms and were not prognostic HR (95% CI): 1.04 (0.54, 2.02). Conclusions: The addition of MDT to SOC ST did not show signal for improved PFS, nor OS difference in patients with OMBC. The trial will not proceed to the Phase III component. Clinical trial information: NCT02364557.", "year": 2022, "publicationDate": "2022-06-01", "publicationTypes": [], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 144, "referenceCount": 0, "influentialCitationCount": 6, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "3574528", "name": "S. Chmura"}, {"authorId": "79269968", "name": "K. Winter"}, {"authorId": "2063609", "name": "W. Woodward"}, {"authorId": "36300971", "name": "V. Borges"}, {"authorId": "2508807", "name": "J. Salama"}, {"authorId": "1396435068", "name": "H. Al-Hallaq"}, {"authorId": "3038811", "name": "M. Matuszak"}, {"authorId": "31027421", "name": "M. Milano"}, {"authorId": "6903939", "name": "N. Jaskowiak"}, {"authorId": "5179617", "name": "H. Bandos"}, {"authorId": "3829256", "name": "J. Bazan"}, {"authorId": "3655369", "name": "R. Nordal"}, {"authorId": "2143996375", "name": "David Lee"}, {"authorId": "2054336", "name": "Benjamin D. Smith"}, {"authorId": "49419069", "name": "E. Mamounas"}, {"authorId": "144669901", "name": "J. White"}], "url": "https://www.semanticscholar.org/paper/6f0671324cef8477205bb5abc1eab07766464cb7", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "e38418068222f41d1f61475751390058dc85a66d", "title": "ClinicalOmicsDB: exploring molecular associations of oncology drug responses in clinical trials", "abstract": "Abstract Matching patients to optimal treatment is challenging, in part due to the limited availability of real-world clinical datasets for predictive biomarker identification. The growing integration of omics profiling into clinical trials presents a new opportunity to tackle this challenge. Here, we introduce ClinicalOmicsDB, a web application for exploring molecular associations of oncology drug responses in clinical trials. This database includes transcriptomic data from 40 clinical trial studies, with 5913 patients spanning 11 cancer types. These studies include 67 treatment arms with a variety of chemotherapy, targeted therapy and immunotherapy drugs, and their combinations, which we organize based on an established ontology for easier navigation. The web application provides users with three options to explore molecular associations of oncology drug responses, focusing on studies, treatments or genes, respectively. Gene set analysis further connects treatment response to pathway activity and tumor microenvironment attributes. The user-friendly web interface of ClinicalOmicsDB streamlines interactive analysis. A Rust-based backend speeds up response time, and application programming interfaces and an R package enable programmatic access. We use three case studies to demonstrate the utility of this resource in human cancer studies. ClinicalOmicsDB is freely available at http://trials.linkedomics.org/.", "year": 2023, "publicationDate": "2023-10-09", "publicationTypes": ["JournalArticle"], "venue": "Nucleic Acids Research", "journal": {"name": "Nucleic Acids Research", "pages": "D1201 - D1209", "volume": "52"}, "citationCount": 12, "referenceCount": 30, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://academic.oup.com/nar/advance-article-pdf/doi/10.1093/nar/gkad871/51956586/gkad871.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2256493547", "name": "C. I. Moon"}, {"authorId": "2256498155", "name": "John M Elizarraras"}, {"authorId": "2256499562", "name": "Jonathan T. Lei"}, {"authorId": "2210523670", "name": "Byron Jia"}, {"authorId": "2243976757", "name": "Bing Zhang"}], "url": "https://www.semanticscholar.org/paper/e38418068222f41d1f61475751390058dc85a66d", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "88470160b5a53b0ea94ab00c71c9abeed3064049", "title": "Efficacy of Neoadjuvant Targeted Therapy in Treatment of Patients with Localised Clear-Cell Renal Cell Carcinoma", "abstract": "Aim This study aimed to evaluate the efficacy of neoadjuvant targeted therapy (TT) in patients with localised clear-cell renal cell carcinoma (RCC). Materials and Methods A special randomised trial was planned and conducted by the Research Department of Plastic and Reconstructive Oncology in the National Cancer Institute of Ukraine for testing the clinical efficacy of neoadjuvant TT in the treatment of clear-cell localised RCC, and the primary endpoint was tumour response evaluation after TT. The secondary endpoints included evaluation of dependence between the use of neoadjuvant TT and the probability of partial nephrectomy and the correlation between tumour size, stage, remaining functioning parenchyma volume, and response to systemic therapy. Results Overall, 118 patients met the inclusion criteria and were randomly assigned to receive combined treatment or surgery alone. The percentage of tumour regression ranged from 0% to 60%, and the median was (95% confidence interval) 20.5 ± 14.3 (16.8–24.3%). Most of the patients had a slightly positive response to TT (3%–29% decrease in tumour size); n = 44 (76.9%) cases. Partial response by the Response Evaluation Criteria in Solid Tumours, version 1.1, was observed in 14 (24.1%) patients and reached a maximum of 60% regression. Tumour reduction in the neoadjuvant TT group allowed kidney preservation in 53 (91.4%) patients. In the control group, the number of organ-sparing procedures was significantly lower (n = 20, 33.3%). The statistical difference was relevant (x2 = 42.1; p < 0.001). Conclusion The positive results of neoadjuvant TT obtained in our study indicate the clinical validity of combined treatment in patients with localised RCC.", "year": 2021, "publicationDate": "2021-04-30", "publicationTypes": ["JournalArticle"], "venue": "Advances in Urology", "journal": {"name": "Advances in Urology", "volume": "2021"}, "citationCount": 7, "referenceCount": 21, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://downloads.hindawi.com/journals/au/2021/6674637.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "16095528", "name": "O. Voylenko"}, {"authorId": "13564358", "name": "O. Stakhovsky"}, {"authorId": "82104420", "name": "I. Vitruk"}, {"authorId": "152944557", "name": "O. Kononenko"}, {"authorId": "50987977", "name": "M. Pikul"}, {"authorId": "82251643", "name": "S. Semko"}, {"authorId": "5789126", "name": "E. Stakhovsky"}], "url": "https://www.semanticscholar.org/paper/88470160b5a53b0ea94ab00c71c9abeed3064049", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "7331e61f5546222a6f1ed149e745bff043bd73ae", "title": "Larotrectinib: A Targeted Therapy for Solid Tumors.", "abstract": "BACKGROUND\nAlthough neurotrophic tyrosine receptor kinase (NTRK) gene fusions are not common in most cancers, they are present in more than 90% of some rare tumors. The U.S. Food and Drug Administration has approved larotrectinib for patients with NTRK gene fusion-positive cancers that meet certain criteria. With ongoing advancements in tumor sequencing, it is anticipated that cancer treatment will be determined by genetic variants rather than by cancer type in the future.\n\n\nOBJECTIVES\nThis article provides an overview of larotrectinib, a targeted therapy.\n\n\nMETHODS\nThis article reviews clinical trial results and highlights implications for oncology nurses caring for patients taking larotrectinib.\n\n\nFINDINGS\nLarotrectinib is an effective treatment option for some patients with NTRK gene fusion-positive cancers. Oncology nurses are key to educating patients on dosing, administration, side effects, and precautions.", "year": 2021, "publicationDate": "2021-04-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Clinical Journal of Oncology Nursing", "journal": {"name": "Clinical journal of oncology nursing", "pages": "\n          181-187\n        ", "volume": "25 2"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2056528676", "name": "Gabriela Mota-George"}, {"authorId": "2977120", "name": "S. Schneider"}], "url": "https://www.semanticscholar.org/paper/7331e61f5546222a6f1ed149e745bff043bd73ae", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "b5ca8ddba37ca54a036174c7d4c44566728360f3", "title": "COGNITION: a prospective precision oncology trial for patients with early breast cancer at high risk following neoadjuvant chemotherapy", "abstract": "Background COGNITION (Comprehensive assessment of clinical features, genomics and further molecular markers to identify patients with early breast cancer for enrolment on marker driven trials) is a diagnostic registry trial that employs genomic and transcriptomic profiling to identify biomarkers in patients with early breast cancer with a high risk for relapse after standard neoadjuvant chemotherapy (NACT) to guide genomics-driven targeted post-neoadjuvant therapy. Patients and methods At National Center for Tumor Diseases Heidelberg patients were biopsied before starting NACT, and for patients with residual tumors after NACT additional biopsy material was collected. Whole-genome/exome and transcriptome sequencing were applied on tumor and corresponding blood samples. Results In the pilot phase 255 patients were enrolled, among which 213 were assessable: thereof 48.8% were identified to be at a high risk for relapse following NACT; 86.4% of 81 patients discussed in the molecular tumor board were eligible for a targeted therapy within the interventional multiarm phase II trial COGNITION-GUIDE (Genomics-guided targeted post neoadjuvant therapy in patients with early breast cancer) starting enrolment in Q4/2022. An in-depth longitudinal analysis at baseline and in residual tumor tissue of 16 patients revealed some cases with clonal evolution but largely stable genetic alterations, suggesting restricted selective pressure of broad-acting cytotoxic neoadjuvant chemotherapies. Conclusions While most precision oncology initiatives focus on metastatic disease, the presented concept offers the opportunity to empower novel therapy options for patients with high-risk early breast cancer in the post-neoadjuvant setting within a biomarker-driven trial and provides the basis to test the value of precision oncology in a curative setting with the overarching goal to increase cure rates.", "year": 2022, "publicationDate": "2022-11-21", "publicationTypes": ["JournalArticle"], "venue": "ESMO Open", "journal": {"name": "ESMO Open", "volume": "7"}, "citationCount": 12, "referenceCount": 29, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.esmoopen.com/article/S205970292200271X/pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2026685061", "name": "C. Pixberg"}, {"authorId": "2290088", "name": "M. Zapatka"}, {"authorId": "6627378", "name": "M. Hlevnjak"}, {"authorId": "2060788849", "name": "S. Benedetto"}, {"authorId": "35464268", "name": "J. P. Suppelna"}, {"authorId": "2300035", "name": "J. Heil"}, {"authorId": "2100595455", "name": "K. Smetanay"}, {"authorId": "83451630", "name": "L. Michel"}, {"authorId": "2293096503", "name": "C. Fremd"}, {"authorId": "117683787", "name": "V. Körber"}, {"authorId": "2260974372", "name": "M. Rübsam"}, {"authorId": "104088409", "name": "L. Buschhorn"}, {"authorId": "2258276037", "name": "S. Heublein"}, {"authorId": "2080535040", "name": "B. Schäfgen"}, {"authorId": "5387406", "name": "M. Golatta"}, {"authorId": "2150285407", "name": "C. Gomez"}, {"authorId": "133681463", "name": "A. von Au"}, {"authorId": "5876867", "name": "M. Wallwiener"}, {"authorId": "2059721381", "name": "S. Wolf"}, {"authorId": "7399971", "name": "N. Dikow"}, {"authorId": "1630919049", "name": "C. Schaaf"}, {"authorId": "1693673891", "name": "E. Gutjahr"}, {"authorId": "47375955", "name": "M. Allgäuer"}, {"authorId": "2149198197", "name": "A. Stenzinger"}, {"authorId": "49142389", "name": "K. Pfütze"}, {"authorId": "143907169", "name": "R. Kirsten"}, {"authorId": "2260928516", "name": "D. Hübschmann"}, {"authorId": "2131388785", "name": "H. Sinn"}, {"authorId": "84610171", "name": "D. Jäger"}, {"authorId": "112983206", "name": "A. Trumpp"}, {"authorId": "153759266", "name": "R. Schlenk"}, {"authorId": "93770425", "name": "T. Höfer"}, {"authorId": "7508211", "name": "V. Thewes"}, {"authorId": "4399118", "name": "A. Schneeweiss"}, {"authorId": "87207213", "name": "P. Lichter"}], "url": "https://www.semanticscholar.org/paper/b5ca8ddba37ca54a036174c7d4c44566728360f3", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "8bf66f3db244eea176c18ea76b5ad1bd75da14f5", "title": "Comparison of Outcomes Between Therapeutic Combinations Based on Immune Checkpoint Inhibitors or Tyrosine Kinase Inhibitor Monotherapy for First-Line Therapy of Patients with Advanced Renal Cell Carcinoma Outside of Clinical Trials: A Real-World Retrospective Multi-Institutional Study", "abstract": null, "year": 2023, "publicationDate": "2023-03-01", "publicationTypes": ["JournalArticle"], "venue": "Targeted oncology", "journal": {"name": "Targeted Oncology", "pages": "209-220", "volume": "18"}, "citationCount": 19, "referenceCount": 49, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2724445", "name": "Hiroki Ishihara"}, {"authorId": "2033289762", "name": "Yukiaki Nemoto"}, {"authorId": "2110774865", "name": "Kazutaka Nakamura"}, {"authorId": "5312087", "name": "H. Tachibana"}, {"authorId": "50378253", "name": "T. Ikeda"}, {"authorId": "11304766", "name": "H. Fukuda"}, {"authorId": "48644458", "name": "Kazuhiko Yoshida"}, {"authorId": "7968043", "name": "Hirohito Kobayashi"}, {"authorId": "2591443", "name": "J. Iizuka"}, {"authorId": "4430076", "name": "H. Shimmura"}, {"authorId": "7342882", "name": "Y. Hashimoto"}, {"authorId": "18902125", "name": "T. Kondo"}, {"authorId": "4090888", "name": "T. Takagi"}], "url": "https://www.semanticscholar.org/paper/8bf66f3db244eea176c18ea76b5ad1bd75da14f5", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "edd7409c5d66da60697a648d428f46a2f8579372", "title": "Operational complexity versus design efficiency: challenges of implementing a phase IIa multiple parallel cohort targeted treatment platform trial in advanced breast cancer", "abstract": "Background Platform trial designs are used increasingly in cancer clinical research and are considered an efficient model for evaluating multiple compounds within a single disease or disease subtype. However, these trial designs can be challenging to operationalise. The use of platform trials in oncology clinical research has increased considerably in recent years as advances in molecular biology enable molecularly defined stratification of patient populations and targeted therapy evaluation. Whereas multiple separate trials may be deemed infeasible, platform designs allow efficient, parallel evaluation of multiple targeted therapies in relatively small biologically defined patient sub-populations with the promise of increased molecular screening efficiency and reduced time for drug evaluation. Whilst the theoretical efficiencies are widely reported, the operational challenges associated with these designs (complexity, cost, regulatory, resource) are not always well understood. Main In this commentary, we describe our practical experience of the implementation and delivery of the UK plasmaMATCH trial, a platform trial in advanced breast cancer, comprising an integrated screening component and multiple parallel downstream mutation-directed therapeutic cohorts. plasmaMATCH reported its primary results within 3 years of opening to recruitment. We reflect on the operational challenges encountered and share lessons learnt to inform the successful conduct of future trials. Key to the success of the plasmaMATCH trial was well co-ordinated stakeholder engagement by an experienced clinical trials unit with expert methodology and trial management expertise, a federated model of clinical leadership, a well-written protocol integrating screening and treatment components and including justification for the chosen structure and intentions for future adaptions, and an integrated funding model with streamlined contractual arrangements across multiple partners. Findings based on our practical experience include the importance of early engagement with the regulators and consideration of a flexible resource infrastructure to allow adequate resource allocation to support concurrent trial activities as adaptions are implemented in parallel to the continued management of patient safety and data quality of the ongoing trial cohorts. Conclusion Platform trial designs allow the efficient reporting of multiple treatment cohorts. Operational challenges can be overcome through multidisciplinary engagement, streamlined contracting processes, rationalised protocol and database design and appropriate resourcing.", "year": 2022, "publicationDate": "2022-05-07", "publicationTypes": ["LettersAndComments"], "venue": "Trials", "journal": {"name": "Trials", "volume": "23"}, "citationCount": 11, "referenceCount": 20, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-022-06312-x", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "47674250", "name": "C. Snowdon"}, {"authorId": "47459447", "name": "S. Kernaghan"}, {"authorId": "1880160", "name": "L. Moretti"}, {"authorId": "28875689", "name": "N. Turner"}, {"authorId": "40440927", "name": "A. Ring"}, {"authorId": "47815593", "name": "K. Wilkinson"}, {"authorId": "153616149", "name": "Sue Martin"}, {"authorId": "2164261413", "name": "S. Foster"}, {"authorId": "5774916", "name": "L. Kilburn"}, {"authorId": "2086127465", "name": "Judith M. Bliss"}], "url": "https://www.semanticscholar.org/paper/edd7409c5d66da60697a648d428f46a2f8579372", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "7dc001c925c6529efa28224ee3984b9acd16079c", "title": "Alliance A031902 (CASPAR): A randomized, phase (ph) 3 trial of enzalutamide with rucaparib/placebo as novel therapy in first-line metastatic castration-resistant prostate cancer (mCRPC).", "abstract": "TPS194 Background: Despite a growing number of treatment options for first line mCRPC, approximately 40% of patients (pts) have radiographic progression within the first year. Androgen receptor (AR) signaling inhibition increases genomic instability with double-strand DNA breaks & co-inhibition of AR & PARP induces synthetic lethality in multiple preclinical models. Homologous recombination repair (HRR) gene aberrations do not appear to be necessary for this synergy as demonstrated in a ph 2 clinical trial of abiraterone & olaparib where this combination improved radiographic progression-free survival (rPFS) in HRR-wild-type pts compared with abiraterone alone. A ph 1b trial has since shown that enzalutamide plus rucaparib has acceptable safety profile & no significant drug-drug interactions (S-DDI). Methods: CASPAR/A031902 (NCT04455750) is a ph 3 study in which 984 pts will be randomized 1:1 to enzalutamide plus rucaparib or placebo. HRR gene aberration is not required for enrollment. All pts will undergo next-generation targeted-exome sequencing from archival tumor tissue (new biopsy only required if no archival tissue available). Treatment will be continued until disease progression & crossover is not allowed. Key eligibility criteria are age ≥ 18 years, ECOG PS 0-2, biopsy-proven prostate adenocarcinoma, progressive (PSA or radiographic) disease per Prostate Cancer Working Group 3 guidelines, measurable or nonmeasurable disease per RECIST 1.1, no prior treatment for mCRPC (prior docetaxel, abiraterone, darolutamide, or apalutamide in non-mCRPC setting is allowed), no significant uncontrolled comorbidity, & no medications with S-DDI with enzalutamide/rucaparib. Hierarchical co-primary endpoints are rPFS & overall survival (OS). The OS analysis will be undertaken as a primary endpoint if the rPFS endpoint is met. For a one-sided logrank test with a type 1 error rate equal to 0.025, the study has 90% power to detect a hazard ratio (HR) of 0.71 in rPFS (median rPFS of 15 & 21 months in control & combination arms, respectively) & 80% power to detect an HR of 0.80 in OS (median OS of 32 & 40 months, respectively). Key secondary endpoints are rPFS & OS in pts with vs without pathogenic BRCA1, BRCA2, or PALB2 alterations; & differences in adverse events & quality of life (QOL) outcomes between the treatment arms. QOL assessments include Functional Assessment of Cancer Therapy–Prostate (FACT-P), Brief Pain Inventory Short Form (BPI-SF) & EQ-5D-5L. A key correlative endpoint is the sensitivity of ctDNA-based testing for alterations in HRR genes. Enrollment to CASPAR began in July 2021 & the study is available for participation to all US-NCTN sites with a projected enrollment of 3 years. Support: U10CA180821, U10CA180882, U24CA196171; U10CA180888; Clovis Oncology; http://acknowledgments.alliancefound.org Clinical trial information: NCT04455750.", "year": 2022, "publicationDate": "2022-02-20", "publicationTypes": [], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 5, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "47652583", "name": "Arpit Rao"}, {"authorId": "145564282", "name": "G. Heller"}, {"authorId": "2082456986", "name": "C. Ryan"}, {"authorId": "33923975", "name": "David J. VanderWeele"}, {"authorId": "2351412", "name": "L. Lewis"}, {"authorId": "2075315309", "name": "A. Tan"}, {"authorId": "32049095", "name": "C. Watt"}, {"authorId": "2122822782", "name": "Ronald Chen"}, {"authorId": "144503041", "name": "M. Kohli"}, {"authorId": "2389485193", "name": "P. Barata"}, {"authorId": "7685227", "name": "B. Gartrell"}, {"authorId": "51168500", "name": "R. Grubb"}, {"authorId": "2555114", "name": "A. Dueck"}, {"authorId": "14320043", "name": "Yujia Wen"}, {"authorId": "144826465", "name": "M. Morris"}], "url": "https://www.semanticscholar.org/paper/7dc001c925c6529efa28224ee3984b9acd16079c", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "ecae46a77c3cdd4046b8c47096d7ef3a947d0a67", "title": "Translating the theranostic concept to neuro-oncology: disrupting barriers.", "abstract": "Theranostics integrate molecular imaging and targeted radionuclide therapy for personalised cancer therapy. Theranostic treatments have shown meaningful efficacy in randomised clinical trials and are approved for clinical use in prostate cancer and neuroendocrine tumours. Brain tumours represent an unmet clinical need and theranostics might offer effective treatment options, although specific issues need to be considered for clinical development. In this Policy Review, we discuss opportunities and challenges of developing targeted radionuclide therapies for the treatment of brain tumours including glioma, meningioma, and brain metastasis. The rational choice of molecular treatment targets is highlighted, including the potential relevance of different types of targeted radionuclide therapeutics, and the role of the blood-brain barrier and blood-tumour barrier. Furthermore, we discuss considerations for effective clinical trial design and conduct, as well as logistical and regulatory challenges for implementation of radionuclide therapies into neuro-oncological practice. Rational development will foster successful translation of the theranostic concept to brain tumours.", "year": 2024, "publicationDate": "2024-09-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "The Lancet Oncology", "journal": {"name": "The Lancet. Oncology", "pages": "\n          e441-e451\n        ", "volume": "25 9"}, "citationCount": 20, "referenceCount": 48, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://pure.eur.nl/ws/files/166942513/Translating_the_theranostic_concept_to_neuro-oncology.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2238774917", "name": "N. Albert"}, {"authorId": "52332900", "name": "E. Le Rhun"}, {"authorId": "3910480", "name": "G. Minniti"}, {"authorId": "1521872594", "name": "M. Mair"}, {"authorId": "2134922293", "name": "N. Galldiks"}, {"authorId": "2625136", "name": "N. Tolboom"}, {"authorId": "1725097", "name": "A. Jakola"}, {"authorId": "2237678790", "name": "Maximilian Niyazi"}, {"authorId": "2304960060", "name": "M. Smits"}, {"authorId": "2254065033", "name": "A. Verger"}, {"authorId": "5111615", "name": "F. Cicone"}, {"authorId": "2317128677", "name": "Michael Weller"}, {"authorId": "2253449102", "name": "M. Preusser"}], "url": "https://www.semanticscholar.org/paper/ecae46a77c3cdd4046b8c47096d7ef3a947d0a67", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "a296d2f695291293af11a3af2e557115f53c043c", "title": "Veterans affairs seamless phase II/III randomized trial of standard systemic therapy with or without PET-directed local therapy for oligorecurrent prostate cancer (VA STARPORT).", "abstract": "TPS203 Background: Two diverging paradigms have been studied in recent years to improve the survival of men with recurrent metastatic prostate cancer (PCa). First, multiple recent phase II randomized trials have demonstrated improved long-term progression-free survival (PFS) with metastasis-directed therapy (MDT) in men with oligorecurrent PCa in the absence of systemic therapy. Yet, most patients receiving MDT for oligorecurrent PCa develop progression in new areas, arguing that systemic therapy is needed to treat occult metastases. The second approach that has recently been studied is whether escalating systemic therapy by adding novel androgen receptor axis targeted agents or chemotherapy improves outcomes in men with metastatic PCa. Multiple phase III randomized trials demonstrate that enhancing hormonal therapy with these therapeutic agents improves progression-free survival (PFS) and overall survival. Therefore, these agents have been integrated into today’s standard systemic therapy (SST) for metastatic recurrence, and SST is the current NCCN guidelines standard of care for recurrent metastatic PCa. The primary goal of our study is to determine if adding PET-directed local therapy (PDLT) to SST improves disease control compared to SST alone in Veterans with oligorecurrent PCa. Methods: VA STARPORT is a phase II/III randomized trial open at 16 VA medical centers comparing SST with or without PDLT in Veterans with oligorecurrent PCa. Key eligibility criteria include prior localized PCa with biochemical recurrence after initial curative-intent local therapy and workup including any FDA-approved PCa PET/CT that reveals oligorecurrence in 1-5 metastatic lesions. The primary endpoint is castration-resistant prostate cancer-free survival (CRPC-free survival). Secondary endpoints include radiographic PFS, clinical PFS, freedom from index lesion progression, toxicity, quality of life, and prostate cancer-specific and overall survival. SST is delivered with an intent for indefinite SST using any NCCN guideline-concordant regimen in both arms. PDLT (Arm 2) consists of surgery or radiation to metastases and any present prostate/prostate bed local recurrence. Metastasis-directed radiation can consist of stereotactic body radiotherapy or elective nodal radiotherapy per clinician discretion from dose/fractionation options defined in the protocol. All participants undergo somatic tumor sequencing using the VA National Precision Oncology Program. Germline sequencing and tumor banking in a separate biorepository study is recommended. Assuming a hazard ratio of 0.60 for SST + PDLT vs SST, two-sided alpha = 0.05 and 90% power, a total of 464 participants will be randomized to generate 166 primary events (CRPC-free survival) by the end of the 48-month active study phase. The study began enrollment in August 2021. Clinical trial information: NCT04787744.", "year": 2022, "publicationDate": "2022-02-20", "publicationTypes": [], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 6, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "6461055", "name": "A. Solanki"}, {"authorId": "2154796184", "name": "Christopher A Schroth"}, {"authorId": "14570447", "name": "Caitlin C. Authier"}, {"authorId": "39581568", "name": "Kimberly Carlson"}, {"authorId": "5291306", "name": "I. Garraway"}, {"authorId": "2154795652", "name": "Tamara Haegerich"}, {"authorId": "47730131", "name": "E. Henry"}, {"authorId": "2119102996", "name": "Jeffrey A. Jones"}, {"authorId": "144500331", "name": "R. Joseph"}, {"authorId": "7980890", "name": "T. Koppes"}, {"authorId": "7012246", "name": "D. Moghanaki"}, {"authorId": "2551415", "name": "M. Quek"}, {"authorId": "2761023", "name": "M. Rettig"}, {"authorId": "2106317381", "name": "Tammy Rhoda"}, {"authorId": "49302227", "name": "T. Ritter"}, {"authorId": "2154797060", "name": "Lisa M Robin"}, {"authorId": "2508807", "name": "J. Salama"}, {"authorId": "32538920", "name": "E. Zacny"}, {"authorId": "47488790", "name": "N. Nickols"}], "url": "https://www.semanticscholar.org/paper/a296d2f695291293af11a3af2e557115f53c043c", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "b22cdd079512ee0a8d750ba97a500a67819163e0", "title": "Advancing therapy for osteosarcoma", "abstract": null, "year": 2021, "publicationDate": "2021-06-15", "publicationTypes": ["Review", "JournalArticle"], "venue": "Nature Reviews Clinical Oncology", "journal": {"name": "Nature Reviews Clinical Oncology", "pages": "609 - 624", "volume": "18"}, "citationCount": 706, "referenceCount": 192, "influentialCitationCount": 21, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "49340846", "name": "Jonathan D Gill"}, {"authorId": "6106414", "name": "R. Gorlick"}], "url": "https://www.semanticscholar.org/paper/b22cdd079512ee0a8d750ba97a500a67819163e0", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "a425a1e2b1d295caa1763ade20bdd5f19eba2a12", "title": "γ-Secretase inhibitor in combination with BCMA chimeric antigen receptor T-cell immunotherapy for individuals with relapsed or refractory multiple myeloma: a phase 1, first-in-human trial.", "abstract": "Background Gamma secretase inhibitors (GSIs) increase B cell maturation antigen (BCMA) density on malignant plasma cells and enhance anti-tumor activity of BCMA CAR T cells in preclinical models. We report results from a clinical trial of 18 patients with relapsed/refractory multiple myeloma (MM) combining escalating doses of a BCMA-targeted therapy with a GSI. Methods Eligible patients were ≥ 18 years old, had relapsed/refractory MM, prior autologous stem cell transplant or persistent disease after > 4 cycles of induction therapy, ECOG ≤ 2, and could have received prior BCMA targeted therapy. The primary endpoints were to evaluate the safety and recommended phase 2 dose (RP2D) of BCMA CAR T cells in combination with crenigacestat, an oral GSI. To assess the impact of the GSI on bone marrow plasma cell BCMA surface density, patients received GSI during a pre-treatment “run-in” consisting of three doses administered 48 hours apart. BCMA CAR T cells were infused at a starting dose of 50 × 106 CAR+ cells, in combination with the GSI dosed three times weekly for up to 9 doses. The trial is registered with ClinicalTrials.gov, NCT03502577, and has met accrual goals. Findings Eighteen patients with MM were treated from July 11, 2018 to April 14, 2021, with a median follow up of 36 months (95% CI, 26 months to not reached). Among the 10 females (56%) and 8 males (44%), 7 had prior treatment with a BCMA targeted agent. Three oral doses of crenigacestat during the “run-in” resulted in a median 12.2-times increase in BCMA density, (range, 3.18 – 156.58, Interquartile range ([IQR] 9.83 to 30.51-times). The most common non-hematologic AEs ≥ grade 3 were hypophosphatemia in 14 (78%), fatigue in 11(61%), hypocalcemia in 9 (50%), and hypertension in 7 (39%). Two deaths reported outside of the 28-day adverse event collection window were related to treatment. Patients were treated at doses up to BCMA CAR 450 × 106 CAR+ cells and the RP2D was not reached. Interpretation Combining a GSI with BCMA CAR T cells is safe, and crenigacestat increases target antigen density. Deep responses were observed amongst heavily pre-treated BCMA exposed and naïve MM patients. Further study of GSIs given with BCMA targeted therapeutics is warranted in clinical trials. This trial was funded by Juno Therapeutics, a Bristol Myers Squibb Company.", "year": 2023, "publicationDate": "2023-07-01", "publicationTypes": ["JournalArticle"], "venue": "The Lancet Oncology", "journal": {"name": "The Lancet. Oncology", "pages": "811 - 822", "volume": "24"}, "citationCount": 82, "referenceCount": 25, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/am/pii/S1470204523002462", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "34689405", "name": "A. Cowan"}, {"authorId": "145967262", "name": "M. Pont"}, {"authorId": "4125705", "name": "Blythe Sather"}, {"authorId": "5959100", "name": "C. Turtle"}, {"authorId": "2378399", "name": "B. Till"}, {"authorId": "37560923", "name": "E. Libby"}, {"authorId": "49238463", "name": "D. Coffey"}, {"authorId": "80242639", "name": "S. Tuazon"}, {"authorId": "2227900268", "name": "B. Wood"}, {"authorId": "144488214", "name": "T. Gooley"}, {"authorId": "51443964", "name": "V. Wu"}, {"authorId": "6633324", "name": "J. Voutsinas"}, {"authorId": "2152113956", "name": "Xiaoling Song"}, {"authorId": "2134298028", "name": "M. Shadman"}, {"authorId": "48719380", "name": "J. Gauthier"}, {"authorId": "38463374", "name": "A. Chapuis"}, {"authorId": "8383435", "name": "F. Milano"}, {"authorId": "3428008", "name": "D. Maloney"}, {"authorId": "3907851", "name": "S. Riddell"}, {"authorId": "2249998877", "name": "D. Green"}], "url": "https://www.semanticscholar.org/paper/a425a1e2b1d295caa1763ade20bdd5f19eba2a12", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "fafff25f50e2112a0d3d8e5a14b555cdafe52cb5", "title": "Statistical operating characteristics of current early phase dose finding designs with toxicity and efficacy in oncology", "abstract": "ABSTRACT Traditional phase I dose finding cancer clinical trial designs aim to determine the maximum tolerated dose (MTD) of the investigational cytotoxic agent based on a single toxicity outcome, assuming a monotone dose-response relationship. However, this assumption might not always hold for newly emerging therapies such as immuno-oncology therapies and molecularly targeted therapies, making conventional dose finding trial designs based on toxicity no longer appropriate. To tackle this issue, numerous early-phase dose finding clinical trial designs have been developed to identify the optimal biological dose (OBD), which takes both toxicity and efficacy outcomes into account. In this article, we review the current model-assisted dose finding designs, BOIN-ET, BOIN12, UBI, TEPI-2, PRINTE, STEIN, and uTPI to identify the OBD and compare their operating characteristics. Extensive simulation studies and a case study using a CAR T-cell therapy phase I trial have been conducted to compare the performance of the aforementioned designs under different possible dose-response relationship scenarios. The simulation results demonstrate that the performance of different designs varies depending on the particular dose-response relationship and the specific metric considered. Based on our simulation results and practical considerations, STEIN, PRINTE, and BOIN12 outperform the other designs from different perspectives.", "year": 2024, "publicationDate": "2024-11-13", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Biopharmaceutical Statistics", "journal": {"name": "Journal of Biopharmaceutical Statistics", "pages": "398 - 418", "volume": "36"}, "citationCount": 3, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2411.08698", "fieldsOfStudy": ["Mathematics", "Medicine"], "s2FieldsOfStudy": [{"category": "Mathematics", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2276529411", "name": "Hao Sun"}, {"authorId": "2403119384", "name": "Hsin-Yu Lin"}, {"authorId": "2146868762", "name": "Jieqi Tu"}, {"authorId": "46618074", "name": "R. Ananthakrishnan"}, {"authorId": "2330573760", "name": "Eunhee Kim"}], "url": "https://www.semanticscholar.org/paper/fafff25f50e2112a0d3d8e5a14b555cdafe52cb5", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "5e4f600b8caa413773763a6e921e19272c642686", "title": "Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel associations between genomic alterations, TMB, and PD-L1", "abstract": "Introduction Matching patients to an effective targeted therapy or immunotherapy is a challenge for advanced and metastatic non-small cell lung cancer (NSCLC), especially when relying on assays that test one marker at a time. Unlike traditional single marker tests, comprehensive genomic profiling (CGP) can simultaneously assess NSCLC tumors for hundreds of genomic biomarkers and markers for immunotherapy response, leading to quicker and more precise matches to therapeutics. Methods In this study, we performed CGP on 7,606 patients with advanced or metastatic NSCLC using the Illumina TruSight Oncology 500 (TSO 500) CGP assay to show its coverage and utility in detecting known and novel features of NSCLC. Results Testing revealed distinct genomic profiles of lung adenocarcinoma and squamous cell carcinomas and detected variants with a current targeted therapy or clinical trial in >72% of patient tumors. Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. Co-occurrence analysis followed by network analysis with gene module detection revealed known and novel co-occurrences between genomic alterations. Further, certain modules of genes with co-occurring genomic alterations had dose-dependent relationships with histology and increasing or decreasing levels of PD-L1 and TMB, suggesting a complex relationship between PD-L1, TMB, and genomic alterations in these gene modules. Discussion This study is the largest clinical study to date utilizing the TSO 500. It provides an opportunity to further characterize the landscape of NSCLC using this newer technology and show its clinical utility in detecting known and novel facets of NSCLC to inform treatment decision-making.", "year": 2024, "publicationDate": "2024-11-27", "publicationTypes": ["JournalArticle"], "venue": "Frontiers in Oncology", "journal": {"name": "Frontiers in Oncology", "volume": "14"}, "citationCount": 2, "referenceCount": 68, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.3389/fonc.2024.1473327", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "12825478", "name": "Zachary D. Wallen"}, {"authorId": "6234506", "name": "M. Nesline"}, {"authorId": "10356286", "name": "M. Tierno"}, {"authorId": "2308591595", "name": "Alison Roos"}, {"authorId": "2308586429", "name": "Erica Schnettler"}, {"authorId": "2296996020", "name": "Hatim Husain"}, {"authorId": "3540865", "name": "P. Sathyan"}, {"authorId": "2264837156", "name": "Brian J Caveney"}, {"authorId": "2264785636", "name": "Marcia Eisenberg"}, {"authorId": "2249264676", "name": "Eric A Severson"}, {"authorId": "2249361942", "name": "Shakti H. Ramkissoon"}], "url": "https://www.semanticscholar.org/paper/5e4f600b8caa413773763a6e921e19272c642686", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "944b0220a74e7919183f965ebc0b8b4e14d734c7", "title": "Regulatory implications of ctDNA in immuno-oncology for solid tumors", "abstract": "In the era of precision oncology, use of circulating tumor DNA (ctDNA) is emerging as a minimally invasive approach for the diagnosis and management of patients with cancer and as an enrichment tool in clinical trials. In recent years, the US Food and Drug Administration has approved multiple ctDNA-based companion diagnostic assays for the safe and effective use of targeted therapies and ctDNA-based assays are also being developed for use with immuno-oncology-based therapies. For early-stage solid tumor cancers, ctDNA may be particularly important to detect molecular residual disease (MRD) to support early implementation of adjuvant or escalated therapy to prevent development of metastatic disease. Clinical trials are also increasingly using ctDNA MRD for patient selection and stratification, with an ultimate goal of improving trial efficiency through use of an enriched patient population. Standardization and harmonization of ctDNA assays and methodologies, along with further clinical validation of ctDNA as a prognostic and predictive biomarker, are necessary before ctDNA may be considered as an efficacy-response biomarker to support regulatory decision making.", "year": 2023, "publicationDate": "2023-02-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "Journal for ImmunoTherapy of Cancer", "journal": {"name": "Journal for Immunotherapy of Cancer", "volume": "11"}, "citationCount": 67, "referenceCount": 97, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://jitc.bmj.com/content/jitc/11/2/e005344.full.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "84346133", "name": "Paz J Vellanki"}, {"authorId": "46848016", "name": "Soma Ghosh"}, {"authorId": "31842685", "name": "A. Pathak"}, {"authorId": "108537923", "name": "Michael J. Fusco"}, {"authorId": "47400210", "name": "E. Bloomquist"}, {"authorId": "14686937", "name": "Shenghui Tang"}, {"authorId": "1499296192", "name": "H. Singh"}, {"authorId": "3019958", "name": "Reena Philip"}, {"authorId": "4116629", "name": "R. Pazdur"}, {"authorId": "2929033", "name": "J. Beaver"}], "url": "https://www.semanticscholar.org/paper/944b0220a74e7919183f965ebc0b8b4e14d734c7", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "e99a6548eff786824489e9cd55fec9728772d9b1", "title": "Randomized Phase III Trial Evaluating Spartalizumab Plus Dabrafenib and Trametinib for BRAF V600–Mutant Unresectable or Metastatic Melanoma", "abstract": "PURPOSE Preclinical data suggest the combination of an anti–programmed death receptor 1 antibody plus dabrafenib and trametinib to have superior antitumor activity compared with dabrafenib plus trametinib alone. These observations are supported by translational evidence suggesting that immune checkpoint inhibitors plus targeted therapy may improve treatment outcomes in patients with BRAF V600–mutant metastatic melanoma. COMBI-i is a phase III trial evaluating spartalizumab, an anti–programmed death receptor 1 antibody, in combination with dabrafenib and trametinib (sparta-DabTram), versus placebo plus dabrafenib and trametinib (placebo-DabTram) in patients with BRAF V600–mutant unresectable or metastatic melanoma. METHODS Patients received spartalizumab 400 mg intravenously every 4 weeks plus dabrafenib 150 mg orally twice daily and trametinib 2 mg orally once daily or placebo-DabTram. Participants were age ≥ 18 years with unresectable or metastatic BRAF V600–mutant melanoma. The primary end point was investigator-assessed progression-free survival. Overall survival was a key secondary end point (ClinicalTrials.gov identifier: NCT02967692). RESULTS At data cutoff (July 1, 2020), the median progression-free survival was 16.2 months (95% CI, 12.7 to 23.9 months) in the sparta-DabTram arm versus 12.0 months (95% CI, 10.2 to 15.4 months) in the placebo-DabTram arm (hazard ratio, 0.82 [95% CI, 0.66 to 1.03]; P = .042 [one-sided; nonsignificant]). The objective response rates were 69% (183 of 267 patients) versus 64% (170 of 265 patients), respectively. Grade ≥ 3 treatment-related adverse events occurred in 55% (146 of 267) of patients in the sparta-DabTram arm and 33% (88 of 264) in the placebo-DabTram arm. CONCLUSION The study did not meet its primary end point; broad first-line use of sparta-DabTram is not supported by these results. Further biomarker-driven investigation may identify patient subpopulations who could benefit from checkpoint inhibitor plus targeted therapy combinations. Primary analysis of COMBI-i, a phase 3 trial of PD-1 + BRAF + MEK inhibition in BRAF-mutant melanoma.", "year": 2022, "publicationDate": "2022-01-14", "publicationTypes": ["JournalArticle"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology", "pages": "1428 - 1438", "volume": "40"}, "citationCount": 143, "referenceCount": 27, "influentialCitationCount": 7, "isOpenAccess": true, "openAccessPdfUrl": "https://ascopubs.org/doi/pdfdirect/10.1200/JCO.21.01601?role=tab", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "144139860", "name": "R. Dummer"}, {"authorId": "2616680", "name": "G. Long"}, {"authorId": "152380617", "name": "C. Robert"}, {"authorId": "5437606", "name": "H. Tawbi"}, {"authorId": "145213930", "name": "K. Flaherty"}, {"authorId": "4771197", "name": "P. Ascierto"}, {"authorId": "145288605", "name": "P. Nathan"}, {"authorId": "48589934", "name": "P. Rutkowski"}, {"authorId": "2150051168", "name": "O. Leonov"}, {"authorId": "6362126", "name": "C. Dutriaux"}, {"authorId": "3664643", "name": "M. Mandalà"}, {"authorId": "4679149", "name": "P. Lorigan"}, {"authorId": "3990356", "name": "P. Ferrucci"}, {"authorId": "50034185", "name": "J. Grob"}, {"authorId": "46298781", "name": "N. Meyer"}, {"authorId": "66456059", "name": "H. Gogas"}, {"authorId": "7551475", "name": "D. Stroyakovskiy"}, {"authorId": "2140888084", "name": "A. Arance"}, {"authorId": "1690847", "name": "J. C. Brase"}, {"authorId": "49841227", "name": "S. Green"}, {"authorId": "50668861", "name": "T. Haas"}, {"authorId": "40349862", "name": "Aisha Masood"}, {"authorId": "49138770", "name": "E. Gasal"}, {"authorId": "145332493", "name": "A. Ribas"}, {"authorId": "144267265", "name": "D. Schadendorf"}], "url": "https://www.semanticscholar.org/paper/e99a6548eff786824489e9cd55fec9728772d9b1", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "f12cefa08e7165df1cb75bb5912bc1bc11695b73", "title": "Lisocabtagene maraleucel as second-line therapy in adults with relapsed or refractory large B-cell lymphoma who were not intended for haematopoietic stem cell transplantation (PILOT): an open-label, phase 2 study.", "abstract": "BACKGROUND\nPatients with relapsed or refractory large B-cell lymphoma after first-line treatment who are not intended for haematopoietic stem-cell transplantation (HSCT) have poor outcomes and limited treatment options. We assessed the antitumour activity and safety of lisocabtagene maraleucel, an autologous, CD19-directed chimeric antigen receptor (CAR) T-cell product, as second-line treatment in adults with relapsed or refractory large B-cell lymphoma not intended for HSCT.\n\n\nMETHODS\nPILOT, an open-label, phase 2 trial done at 18 clinical sites in the USA, included adults aged 18 years or older who had relapsed or refractory large B-cell lymphoma and PET-positive disease, had received first-line therapy containing an anthracycline and a CD20-targeted agent, were not intended for HSCT by their physician, and met at least one prespecified transplantation not intended criterion. Patients received lymphodepleting chemotherapy (intravenous fludarabine 30 mg/m2 and intravenous cyclophosphamide 300 mg/m2 daily for 3 days) followed 2-7 days later by two sequential lisocabtagene maraleucel infusions (equal target doses of CD8+ and CD4+ CAR+ T cells for a total target dose of 100 × 106 CAR+ T cells). The primary endpoint was the overall response rate and was assessed in all patients who received lisocabtagene maraleucel and had confirmed PET-positive disease before lisocabtagene maraleucel administration based on an independent review committee according to the Lugano 2014 criteria. Safety was assessed in all patients who received lisocabtagene maraleucel. Patient follow-up is ongoing. This study is registered with ClinicalTrials.gov, NCT03483103.\n\n\nFINDINGS\nBetween July 26, 2018, and Sept 24, 2021 (data cutoff for the primary analysis), 74 patients underwent leukapheresis and 61 received lisocabtagene maraleucel (efficacy and safety sets); median age was 74 years (IQR 70-78), 24 (39%) patients were women versus 37 (61%) men, and 54 (89%) patients were White. 16 (26%) of 61 patients had an Eastern Cooperative Oncology Group performance status of 2, 33 (54%) had refractory disease, 13 (21%) relapsed within 1 year of first-line therapy, and 15 (25%) relapsed after 12 months of first-line therapy. Median on-study follow-up was 12·3 months (IQR 6·1-18·0). 49 (80% [95% CI 68-89]; p<0·0001) patients had an overall response. The most common grade 3 or worse treatment-emergent adverse events were neutropenia (29 [48%] patients), leukopenia (13 [21%]), and thrombocytopenia (12 [20%]). Lisocabtagene maraleucel-related serious treatment-emergent adverse events were reported in 13 (21%) patients. There were no treatment-related deaths. Cytokine release syndrome occurred in 23 (38%; grade 3 in one) patients and neurological events in 19 (31%; grade 3 in three) patients, with no grade 4 events or deaths.\n\n\nINTERPRETATION\nThese results support lisocabtagene maraleucel as a potential second-line treatment in patients with large B-cell lymphoma for whom HSCT is not intended.\n\n\nFUNDING\nJuno Therapeutics, a Bristol-Myers Squibb company.", "year": 2022, "publicationDate": "2022-07-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "The Lancet Oncology", "journal": {"name": "The Lancet. Oncology"}, "citationCount": 197, "referenceCount": 28, "influentialCitationCount": 14, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "3956768", "name": "A. Sehgal"}, {"authorId": "2308704142", "name": "D. Hoda"}, {"authorId": "7998565", "name": "P. Riedell"}, {"authorId": "2132616740", "name": "N. Ghosh"}, {"authorId": "4697872", "name": "M. Hamadani"}, {"authorId": "17256013", "name": "G. Hildebrandt"}, {"authorId": "36349666", "name": "J. Godwin"}, {"authorId": "13269290", "name": "P. Reagan"}, {"authorId": "1387235775", "name": "N. Wagner-Johnston"}, {"authorId": "6148372", "name": "J. Essell"}, {"authorId": "50423981", "name": "R. Nath"}, {"authorId": "38812173", "name": "S. Solomon"}, {"authorId": "2176091645", "name": "R. Champion"}, {"authorId": "2276163087", "name": "E. Licitra"}, {"authorId": "39348745", "name": "S. Fanning"}, {"authorId": "153027820", "name": "Neel K. Gupta"}, {"authorId": "8523423", "name": "R. Dubowy"}, {"authorId": "1396108638", "name": "A. D’Andrea"}, {"authorId": "2152508411", "name": "Lei Wang"}, {"authorId": "153219945", "name": "K. Ogasawara"}, {"authorId": "40522973", "name": "J. Thorpe"}, {"authorId": "3501990", "name": "L. Gordon"}], "url": "https://www.semanticscholar.org/paper/f12cefa08e7165df1cb75bb5912bc1bc11695b73", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "e8f54998b3465e53fc93a467b91c1df5586cf148", "title": "Preoperative and Postoperative Systemic Therapy for Operable Non-Small-Cell Lung Cancer.", "abstract": "Cisplatin-based adjuvant chemotherapy remains the standard of care for patients with resected stage II or III non-small-cell lung cancer. However, biomarker-informed clinical trials are starting to push the management of early-stage lung cancer beyond cytotoxic chemotherapy. This review explores recent and ongoing studies focused on improving cytotoxic chemotherapy and incorporating targeted and immunotherapies in the management of early-stage, resectable lung cancer. Adjuvant osimertinib for patients with EGFR-mutant tumors, preoperative chemoimmunotherapy, and adjuvant immunotherapy could improve outcomes for selected patients with resectable lung cancer, and ongoing or planned studies leveraging biomarkers, immunotherapy, and targeted therapy may further improve survival. We also discuss the unique barriers associated with clinical trials of early-stage lung cancer and the need for innovative trial designs to overcome these challenges.", "year": 2022, "publicationDate": "2022-01-05", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of clinical oncology : official journal of the American Society of Clinical Oncology", "pages": "\n          JCO2101589\n        "}, "citationCount": 147, "referenceCount": 22, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853628", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "4761088", "name": "J. Chaft"}, {"authorId": "80280201", "name": "Y. Shyr"}, {"authorId": "7216563", "name": "B. Sepesi"}, {"authorId": "2269294", "name": "P. Forde"}], "url": "https://www.semanticscholar.org/paper/e8f54998b3465e53fc93a467b91c1df5586cf148", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "5e39ff994071fa36a82a11f375ff4bc34b3a4496", "title": "Oncolytic viral therapy engenders a clinical response in a recurrent ovarian cancer patient", "abstract": "Platinum-resistant ovarian cancer frequently develops in response to multiple lines of chemotherapy, whereupon the disease becomes relatively intractable and clinical recourse is limited. We document a 58-year-old, advanced-stage, platinum-resistant ovarian cancer patient who previously failed numerous cytotoxic and targeted therapy regimens. She was referred to our gynecologic oncology service with a California (CA)-125 of 3194 U/mL and underwent a modified vaccinia virus coinciding with an Institutional Review Board-approved clinical trial. Following the oncolytic therapy and cycle 8 chemotherapy, the patient’s CA-125 declined to 440 U/mL; a computerized tomography scan of the abdomen and pelvis revealed a partial response to therapy. The favorable clinical benefit encountered in our case study indicates that the combination of oncolytic viral therapy and chemotherapy should be considered as a therapeutic option for heavily pretreated ovarian patients.", "year": 2022, "publicationDate": "2022-03-23", "publicationTypes": ["JournalArticle", "Review"], "venue": "Anti-Cancer Drugs", "journal": {"name": "Anti-Cancer Drugs", "pages": "513 - 516", "volume": "33"}, "citationCount": 2, "referenceCount": 16, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "4450204", "name": "J. Micha"}, {"authorId": "5931409", "name": "M. Rettenmaier"}, {"authorId": "1388232211", "name": "Peter D Giuliano"}, {"authorId": "51308608", "name": "R. Bohart"}, {"authorId": "31472104", "name": "B. Goldstein"}], "url": "https://www.semanticscholar.org/paper/5e39ff994071fa36a82a11f375ff4bc34b3a4496", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "ab1e597634561606fad643ad0d5b02cf9e15bf33", "title": "P06.04.A FIRST IN HUMAN - TARGETING ANDROGEN RECEPTOR FOR GLIOBLASTOMA THERAPY", "abstract": "\n \n \n Glioblastoma represents a significant therapeutic challenge due to its aggressive nature, necessitating the development of effective targeted therapies. In a pivotal study, the amplification of the androgen receptor in 56% of glioblastomas was observed, shedding light on its therapeutic potential. Through extensive research, our team demonstrated the efficacy of the androgen receptor antagonist, enzalutamide (Xtandi), in prolonging lifespan in a mouse model of human glioblastoma. Collaborating with the Cyclotron and PET/CT teams, we established [18F]-FDHT PET/CT imaging, facilitating real-time detection of androgen receptor expression within brain tumors and enabling precise patient selection for targeted therapy.\n \n \n \n To proceed with a clinical trial, we conducted several steps. Initially, we examined the pharmacokinetics of enzalutamide and temozolomide, both as monotherapy and in combination, over multiple time points up to 96 hours, analyzing plasma and brain samples by LC-MS/MS. Additionally, we assessed the efficacy of PET/CT imaging for therapy response monitoring. After confirming androgen receptor expression via PET scan, patients underwent a 10-day regimen of escalating doses of the androgen antagonist Xtandi, administered daily, followed by a second PET scan.\n \n \n \n In the pharmacokinetic analysis, we found that the half-life (t1/2) of enzalutamide remained consistent in both plasma and brain tissue when combined with temozolomide, compared to monotherapy. Notably, the t1/2 of temozolomide increased significantly when administered concurrently, rising from 1.8 to 4.45 in plasma and from 0.88 to 7.25 in brain tissue, respectively. These results informed the clinical trial protocol design. Regarding the PET/CT study, the outcomes were promising: two potential responders identified through imaging received either 40 or 80 mg of Xtandi. The patient who received 80 mg exhibited a significant reduction in tracer uptake after ten days of treatment, accompanied by tumor shrinkage and tangible improvements in mobility and quality of life, highlighting the transformative potential of our approach.\n \n \n \n Encouraged by these results, we initiated a clinical trial to determine the safety and tolerability of Enzalutamide in conjunction with radiotherapy (RT) and temozolomide (TMZ), to assess clinical response using Response Assessment in Neuro-Oncology (RANO) criteria and to characterize the pharmacokinetics of Enzalutamide combined with TMZ. We have recently enrolled two patients for this study, and eagerly anticipate presenting the results of these participants, along with potentially others, during the forthcoming meeting. With the potential to rapidly translate these findings into clinical practice, our fast-track trial represents a beacon of hope for Glioblastoma patients worldwide.\n", "year": 2024, "publicationDate": "2024-10-01", "publicationTypes": ["JournalArticle"], "venue": "Neuro-Oncology", "journal": {"name": "Neuro-Oncology"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}], "authors": [{"authorId": "5955312", "name": "I. Lavon"}, {"authorId": "41034871", "name": "A. Mordechai"}, {"authorId": "2249537700", "name": "A. Lossos"}], "url": "https://www.semanticscholar.org/paper/ab1e597634561606fad643ad0d5b02cf9e15bf33", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "491cfd54a1c382f3a4c5b2e03527222e85b9d051", "title": "Synthetic lethality-mediated precision oncology via the tumor transcriptome", "abstract": "Summary Precision oncology has made significant advances, mainly by targeting actionable mutations in cancer driver genes. Aiming to expand treatment opportunities, recent studies have begun to explore the utility of tumor transcriptome to guide patient treatment. Here we introduce SELECT (SynthEtic LEthality and rescue-mediated precision onCology via the Transcriptome), a precision oncology framework harnessing genetic interactions to predict patient response to cancer therapy from the tumor transcriptome. SELECT is tested on a broad collection of 35 published targeted and immunotherapy clinical trials from 10 different cancer types. It is predictive of patients’ response in 80% of these clinical trials and in the recent multi-arm WINTHER trial. The predictive signatures and the code are made publicly available for academic use, laying a basis for future prospective clinical studies.", "year": 2021, "publicationDate": "2021-04-01", "publicationTypes": ["JournalArticle"], "venue": "Cell", "journal": {"name": "Cell", "pages": "2487 - 2502.e13", "volume": "184"}, "citationCount": 130, "referenceCount": 104, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.cell.com/article/S0092867421003615/pdf", "fieldsOfStudy": ["Medicine", "Biology"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Biology", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}], "authors": [{"authorId": "48174484", "name": "J. S. Lee"}, {"authorId": "2074970", "name": "N. Nair"}, {"authorId": "90058988", "name": "Gal Dinstag"}, {"authorId": "2069250499", "name": "Lesley M. Chapman"}, {"authorId": "83046322", "name": "Youngmin Chung"}, {"authorId": "2119043826", "name": "Kun Wang"}, {"authorId": "89140690", "name": "Sanju Sinha"}, {"authorId": "51223399", "name": "H. Cha"}, {"authorId": "2376417658", "name": "Dasol Kim"}, {"authorId": "2273470236", "name": "Alexander Schperberg"}, {"authorId": "1388691415", "name": "A. Srinivasan"}, {"authorId": "143774741", "name": "V. Lazar"}, {"authorId": "2679741", "name": "E. Rubin"}, {"authorId": "145797362", "name": "Sohyun Hwang"}, {"authorId": "47986421", "name": "R. Berger"}, {"authorId": "3257850", "name": "T. Beker"}, {"authorId": "4303715", "name": "Z. Ronai"}, {"authorId": "1716201", "name": "S. Hannenhalli"}, {"authorId": "144390029", "name": "M. Gilbert"}, {"authorId": "49319257", "name": "R. Kurzrock"}, {"authorId": "153310556", "name": "Se-Hoon Lee"}, {"authorId": "2105335439", "name": "Kenneth D. Aldape"}, {"authorId": "1779370", "name": "E. Ruppin"}], "url": "https://www.semanticscholar.org/paper/491cfd54a1c382f3a4c5b2e03527222e85b9d051", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "c04d549ced3aa1580ad8cc758537236934df5530", "title": "Erdafitinb in patients with FGFR-altered tumors: Results from the NCI-COG Pediatric MATCH trial arm B (APEC1621B).", "abstract": "10007 Background: The NCI-Children’s Oncology Group (COG) Pediatric Molecular Analysis for Therapy Choice (MATCH) trial assigns patients aged 1-21 years with relapsed or refractory solid tumors, CNS tumors, lymphomas, and histiocytic disorders to phase 2 treatment arms of molecularly-targeted therapies based on genetic alterations in their tumor. Arm B (APEC1621B) evaluated the orally bioavailable FGFR inhibitor erdafitinib in patients whose tumors harbored activating alterations in FGFR 1/2/3/4. Methods: Patients received oral erdafitinib 4.7 mg/m2/dose (Max dose: 8 mg) daily for 28-day cycles until disease progression or drug related dose limiting toxicity (Max 26 cycles). Disease assessments were performed every 2-3 cycles. The primary endpoint was objective response rate; secondary endpoints included progression free survival (PFS). Results: A total of 20 evaluable patients (median age: 15 yrs) were enrolled from June 2018 to July 2022 in this first study of erdafitinib in pediatric patients. The most common diagnosis (n = 17) was glioma or glioneuronal tumor (11 low grade and 6 high grade). Three patients had non-CNS solid tumors (1 each with neuroblastoma, osteosarcoma, and rhabdomyosarcoma). FGFR alterations detected consisted of activating hotspot mutations in FGFR1 (n = 16), FGFR2 (n = 1), FGFR4 (n = 1), and FGFR1 fusions (n = 2; FGFR1: TACC1, FGFR1: TACC3). Partial responses were confirmed by central review in 2/20 patients (10%, 90%CI: 3.4%, 26.2%), both with low grade gliomas or glioneuronal tumors (LGG, LGGNT) and FGFR1 hotspot mutations (K687E and N577K). A best response of stable disease (SD) was observed in 6 additional patients with gliomas with a median duration of SD of 6.5 cycles. Six-month PFS was 45% (95% CI: 23.1%, 64.7%) and six-month OS was 89.7% (95%CI: 64.8%, 97.3%). Treatment related adverse events included those previously reported with FGFR inhibitors including hyperphosphatemia and nail changes or infections. Grade 1 vision changes were also reported. There was one Grade 3 spinal cord compression and one Grade 4 intracranial hemorrhage. Conclusions: Erdafitinib was generally well tolerated in this heavily pre-treated cohort of children with relapsed tumors harboring FGFR alterations. Partial responses or stable disease were observed in the majority (6/11, 54%) of patients with FGFR1-mutant low grade gliomas or glioneuronal tumors, suggesting the possible benefit of FGFR inhibitor therapy for these patients. Further studies would be necessary to more thoroughly evaluate the activity of erdafitinib for patients with other histologies and FGFR alteration types or combination approaches that include other targeted and/or cytotoxic agents. Clinical trial information: NCT03210714 .", "year": 2023, "publicationDate": "2023-06-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 21, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2023.41.16_suppl.10007", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "49250072", "name": "Alice Lee"}, {"authorId": "4307894", "name": "A. Chou"}, {"authorId": "2107182521", "name": "P. Williams"}, {"authorId": "1397965328", "name": "S. Roy-Chowdhuri"}, {"authorId": "50376247", "name": "D. Patton"}, {"authorId": "81951923", "name": "Brent Coffey"}, {"authorId": "143955435", "name": "J. Reid"}, {"authorId": "2105556583", "name": "J. Piao"}, {"authorId": "147364147", "name": "Lauren Saguilig"}, {"authorId": "6709309", "name": "T. Alonzo"}, {"authorId": "32857822", "name": "S. Berg"}, {"authorId": "37056856", "name": "A. Jaju"}, {"authorId": "2121593827", "name": "E. Fox"}, {"authorId": "143835717", "name": "D. Hawkins"}, {"authorId": "17562871", "name": "M. Mooney"}, {"authorId": "119645917", "name": "N. Takebe"}, {"authorId": "6641804", "name": "J. V. Tricoli"}, {"authorId": "5305242", "name": "K. Janeway"}, {"authorId": "3521599", "name": "N. Seibel"}, {"authorId": "4632467", "name": "D. Parsons"}], "url": "https://www.semanticscholar.org/paper/c04d549ced3aa1580ad8cc758537236934df5530", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "512f35edc38a24d89ff987f7c329cd5ae9161b96", "title": "Precision oncology medicines and the need for real world evidence acceptance in health technology assessment: Importance of patient involvement in sustainable healthcare.", "abstract": "Precision oncology has made remarkable strides in improving clinical outcomes, offering hope to patients with historically difficult-to-treat, as well as rare or neglected cancers. However, despite rapid advancement, precision oncology has reached a critical juncture, where patient access to these life-saving medicines may be hampered by strict requirements by Health Technology Assessment (HTA) bodies for randomised controlled trials (RCTs) for assessing new medicines against appropriate comparator. The very nature of precision oncology-matching a tumour's unique molecular alterations to targeted therapies predicted to elicit response-can make the use of RCTs very difficult, as only a very small number of patients might qualify for a given therapy within a traditional clinical trial setting. Real-world evidence (RWE) has been accepted for regulatory decision-making but has yet to reach widespread acceptance by HTA bodies. As the oncology treatment landscape has evolved towards favouring the concept of precision oncology, there is a growing need for flexibility in the way HTA bodies evaluate new medicines. We must acknowledge that current assessment methodologies can limit access to life-changing medicines for many patients who have no alternative options and that a growing number of precision oncology medicines with proven clinical benefits in rare tumours cannot be reasonably evaluated using traditional methodologies. The objectives of this paper are to advocate a change in mindset regarding best practices in drug assessment models and to propose alternative approaches when considering indications for which RWE is the most compelling data source available.", "year": 2023, "publicationDate": "2023-09-01", "publicationTypes": ["JournalArticle"], "venue": "European Journal of Cancer", "journal": {"name": "European journal of cancer", "pages": "\n          113323\n        ", "volume": "193"}, "citationCount": 9, "referenceCount": 21, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.ejca.2023.113323", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2238093333", "name": "Jan Geissler"}, {"authorId": "2238095505", "name": "Lydia E Makaroff"}, {"authorId": "2238098079", "name": "Bärbel Söhlke"}, {"authorId": "2244644988", "name": "Carsten Bokemeyer"}], "url": "https://www.semanticscholar.org/paper/512f35edc38a24d89ff987f7c329cd5ae9161b96", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "cf5de86095e17b4b12bf4508a4b6aed744dfa291", "title": "Therapeutic potential of oncolytic viruses in the era of precision oncology", "abstract": "ABSTRACT Oncolytic virus (OV) therapy has been shown to be an effective targeted cancer therapy treatment in recent years, providing an avenue of treatment that poses no damage to surrounding healthy tissues. Not only do OVs cause direct oncolysis, but they also amplify both innate and adaptive immune responses generating long-term anti-tumour immunity. Genetically engineered OVs have become the common promising strategy to enhance anti-tumour immunity, safety, and efficacy as well as targeted delivery. The studies of various OVs have been accomplished through phase I-III clinical trial studies. In addition, the uses of carrier platforms of organic materials such as polymer chains, liposomes, hydrogels, and cell carriers have played a vital role in the potentially targeted delivery of OVs. The mechanism, rational design, recent clinical trials, applications, and the development of targeted delivery platforms of OVs will be discussed in this review.", "year": 2023, "publicationDate": "2023-06-28", "publicationTypes": ["Review", "JournalArticle"], "venue": "Biomaterials translational", "journal": {"name": "Biomaterials Translational", "pages": "67 - 84", "volume": "4"}, "citationCount": 7, "referenceCount": 130, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}], "authors": [{"authorId": "2122035465", "name": "Monchupa Kingsak"}, {"authorId": "2133852974", "name": "Thongpon Meethong"}, {"authorId": "2189004127", "name": "Jinnawat Jongkhumkrong"}, {"authorId": "2254015981", "name": "Li Cai"}, {"authorId": "2281747939", "name": "Qian Wang"}], "url": "https://www.semanticscholar.org/paper/cf5de86095e17b4b12bf4508a4b6aed744dfa291", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "2e300b5bfee254a4ea6beaecbbbdd23dc0cd3ebc", "title": "Design of Phase II Oncology Trials Evaluating Combinations of Experimental Agents.", "abstract": "We consider the design of phase II trials evaluating combinations of experimental therapies. In the modern era, many immunotherapy and targeted therapy regimens are being developed as combination regimens, including combinations consisting only of experimental agents. In some clinical/drug development scenarios, it may be difficult to isolate the effect of the individual agents making up a combination of this type, which makes the evaluation of the combination challenging. One such scenario arises when none of the agents making up the experimental combination have demonstrated single-agent activity in the clinical setting of interest. One solution to this problem is to employ a randomized comparative trial in which the combination of interest is compared with one or both of its component agents, but because all arms in such a trial would be experimental, some modifications to more traditional randomized comparative phase II trials must be made. In this manuscript, we present sensible modifications to randomized phase II trial designs that can be employed in two common drug development scenarios of this type and provide a detailed discussion of the practical aspects of designing these trials. We also include two worked examples to further illustrate how to design such a trial.", "year": 2023, "publicationDate": "2023-03-21", "publicationTypes": ["JournalArticle"], "venue": "Journal of the National Cancer Institute", "journal": {"name": "Journal of the National Cancer Institute"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://academic.oup.com/jnci/advance-article-pdf/doi/10.1093/jnci/djad052/49584032/djad052.pdf", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "66478424", "name": "E. Sharon"}, {"authorId": "153664049", "name": "Jared C. Foster"}], "url": "https://www.semanticscholar.org/paper/2e300b5bfee254a4ea6beaecbbbdd23dc0cd3ebc", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "720a5708ed9845aa0bdc4dda1e5f22124ced51e8", "title": "Impact of Geriatric Assessment and Management on Quality of Life, Unplanned Hospitalizations, Toxicity, and Survival for Older Adults With Cancer: The Randomized 5C Trial", "abstract": "PURPOSE American Society of Clinical Oncology recommends that older adults with cancer being considered for chemotherapy receive geriatric assessment (GA) and management (GAM), but few randomized controlled trials have examined its impact on quality of life (QOL). PATIENTS AND METHODS The 5C study was a two-group parallel 1:1 single-blind multicenter randomized controlled trial of GAM for 6 months versus usual oncologic care. Eligible patients were age 70+ years, diagnosed with a solid tumor, lymphoma, or myeloma, referred for first-/second-line chemotherapy or immunotherapy or targeted therapy, and had an Eastern Cooperative Oncology Group performance status of 0-2. The primary outcome QOL was measured with the global health scale of the European Organisation for the Research and Treatment of Cancer QOL questionnaire and analyzed with a pattern mixture model using an intent-to-treat approach (at 6 and 12 months). Secondary outcomes included functional status, grade 3-5 treatment toxicity; health care use; satisfaction; cancer treatment plan modification; and overall survival. RESULTS From March 2018 to March 2020, 350 participants were enrolled. Mean age was 76 years and 40.3% were female. Fifty-four percent started treatment with palliative intent. Eighty-one (23.1%) patients died. GAM did not improve QOL (global QOL of 4.4 points [95% CI, 0.9 to 8.0] favoring the control arm). There was also no difference in survival, change in treatment plan, unplanned hospitalization/emergency department visits, and treatment toxicity between groups. CONCLUSION GAM did not improve QOL. Most intervention group participants received GA on or after treatment initiation per patient request. Considering recent completed trials, GA may have benefit if completed before treatment selection. The COVID-19 pandemic may have affected our QOL outcome and intervention delivery for some participants.", "year": 2022, "publicationDate": "2022-12-06", "publicationTypes": ["JournalArticle"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology", "pages": "847 - 858", "volume": "41"}, "citationCount": 55, "referenceCount": 45, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902020", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "3591972", "name": "M. Puts"}, {"authorId": "1454390739", "name": "N. Alqurini"}, {"authorId": "3788321", "name": "F. Strohschein"}, {"authorId": "51257258", "name": "R. Koneru"}, {"authorId": "6291912", "name": "E. Szumacher"}, {"authorId": "13019235", "name": "C. Mariano"}, {"authorId": "5281112", "name": "J. Monette"}, {"authorId": "79037298", "name": "T. Hsu"}, {"authorId": "4678205", "name": "S. Brennenstuhl"}, {"authorId": "2048066270", "name": "B. McLean"}, {"authorId": "1636495551", "name": "A. Wills"}, {"authorId": "47326376", "name": "A. Berger"}, {"authorId": "50990688", "name": "E. Amir"}, {"authorId": "1404252777", "name": "L. Romanovsky"}, {"authorId": "114684943", "name": "Anson Li"}, {"authorId": "40072629", "name": "R. Mehta"}, {"authorId": "3551389", "name": "M. Krzyzanowska"}, {"authorId": "10716604", "name": "C. Elser"}, {"authorId": "2542264", "name": "R. Jang"}, {"authorId": "5131797", "name": "A. Prica"}, {"authorId": "1403326911", "name": "D. Wan-Chow-Wah"}, {"authorId": "26410832", "name": "E. Pitters"}, {"authorId": "5948469", "name": "U. Emmenegger"}, {"authorId": "2249203462", "name": "I. Menjak"}, {"authorId": "46855913", "name": "S. Bergman"}, {"authorId": "1960655", "name": "M. Lemonde"}, {"authorId": "144903883", "name": "H. Breunis"}, {"authorId": "80676790", "name": "F. Béland"}, {"authorId": "6607143", "name": "S. Alibhai"}], "url": "https://www.semanticscholar.org/paper/720a5708ed9845aa0bdc4dda1e5f22124ced51e8", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "ad91a4806b8da1d9d2a4d278752e47e0c737d155", "title": "Current Status of Human Papillomavirus–Targeted Therapies Development in Head and Neck Cancer", "abstract": "PURPOSE While the incidence of smoking-related head and neck squamous cell carcinoma (HNSCC) has been declining, that of human papillomavirus (HPV)–mediated HNSCC has rapidly increased in the past decades worldwide. Despite rapid advances in therapeutics for solid tumors with novel immunotherapy and targeted therapeutic agents, no breakthroughs have yet been made in the treatment of advanced HPV+ HNSCCs. This review aims to summarize the concepts and designs, early trial results, and future directions of various HPV-targeted experimental therapeutics for HPV+ HNSCC. MATERIALS AND METHODS Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, a systemic literature search of PubMed was conducted for HPV-targeted therapeutics using the following search terms: HPV, head and neck squamous cell carcinoma, and therapy. For clinical trial data, publications, major oncology conference abstracts, and the National Institutes of Health Clinical Trials Registry (ClinicalTrials.gov) information were reviewed. This review focused on the ones that are in the clinical stage and currently in active ongoing evaluation. The therapeutics not actively evaluated in HNSCC, in the preclinical stage, or terminated for further development were excluded. RESULTS Diverse approaches are being actively explored to target HPV+ HNSCC, including therapeutic vaccines of various modalities, HPV-specific immune cell–activating agents, and adaptive cellular therapeutics. All these novel agents use immune-based mechanisms and target constitutively expressed oncogenic HPV E6 and/or E7 viral proteins. Most therapeutics demonstrated excellent safety but single-agent activities are only modest. Many are being tested in combination with immune checkpoint inhibitors. CONCLUSION Our review summarized various novel HPV-targeted therapeutics that are in the clinical phase for HPV+ HNSCC. Early-phase trial data suggest the feasibility and promising efficacy. Further strategies, including selecting the optimal combination and understanding and overcoming resistant mechanisms, are warranted for successful development.", "year": 2023, "publicationDate": "2023-06-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "JCO Precision Oncology", "journal": {"name": "JCO Precision Oncology", "volume": "7"}, "citationCount": 6, "referenceCount": 44, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2296388586", "name": "J. C. Park"}, {"authorId": "2139917049", "name": "Brittany Bertaux"}, {"authorId": "2331257494", "name": "Junseok Park"}, {"authorId": "2118884888", "name": "Seongwoo Park"}], "url": "https://www.semanticscholar.org/paper/ad91a4806b8da1d9d2a4d278752e47e0c737d155", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "0417bcd4d2409a6d85b85ecee4c4344dc03a1acb", "title": "Efficacy and safety of aumolertinib combined with or without chemotherapy as an adjuvant treatment for stage II-IIIA non-small cell lung cancer following complete tumour resection: The first third-generation EGFR-TKI versus chemotherapy phase III clinical study (APEX).", "abstract": "TPS8117 Background: Patients with stage II-III A non-small cell lung cancer (NSCLC) can benefit from adjuvant targeted therapy. ADAURA study shows a remarkable advantage of disease-free survival (DFS). However, there are still unresolved clinical issues. Firstly, the control group in the trial is received placebo, making it impossible to directly compare the efficacy of adjuvant targeted therapy with the traditionally recommended adjuvant chemotherapy in guidelines. Thus, it cannot address the direct comparison of third-generation TKIs with the current standard therapy (chemotherapy). Secondly, the necessity of combining chemotherapy with adjuvant targeted therapy need to explored. Aumolertinib is a third-generation epidermal growth factor receptor- tyrosine kinase inhibitor (EGFR-TKI) that potently and selectively inhibits EGFR sensitizing and EGFR T790M resistance mutations. This study aims to evaluate the efficacy and safety of aumolertinib combined with or without chemotherapy as adjuvant treatment for EGFR-sensitive mutations stage II-III A non-squamous NSCLC patients. Methods: This is a multicenter, randomized, open label, phase III study. Patients with histologically confirmed stage II-III A non-squamous NSCLC harboring EGFR mutations without prior EGFR TKI treatment and R0 resection are eligible for this study. The performance status (Eastern Cooperative Oncology Group) is 0 or 1. This trial prepared to enroll approximately 606 patients, will be randomized (3:2:1) to receive either aumolertinib alone (110mg, po, once daily) or aumolertinib (110mg, po, once daily) plus pemetrexed (500mg/m2, iv) and cisplatin (500mg/m2, iv) or pemetrexed (500mg/m2, iv) plus cisplatin (500mg/m2, iv). The first patient was enrolled on August 2, 2021. The primary end point is DFS, The secondary endpoints include 2, 3, 4, 5-year DFS rates, 5-year overall survival (OS), OS, safety and quality of life. Adverse effects were graded per CTCAE v.4.0. This trial is registered as NCT04762459. Clinical trial information: NCT04762459 .", "year": 2024, "publicationDate": "2024-06-01", "publicationTypes": ["JournalArticle"], "venue": "Journal of Clinical Oncology", "journal": {"name": "Journal of Clinical Oncology"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "2305909713", "name": "Feng Tan"}, {"authorId": "2242345987", "name": "Zhijie Wang"}, {"authorId": "2249158080", "name": "G. Feng"}, {"authorId": "2428387574", "name": "Daqiang Sun"}, {"authorId": "2237099187", "name": "Haitao Ma"}, {"authorId": "2280735605", "name": "Tao Jiang"}, {"authorId": "2277957985", "name": "Sihua Wang"}, {"authorId": "2286842225", "name": "Hongxu Liu"}, {"authorId": "2249326237", "name": "Weidong Hu"}, {"authorId": "2305770387", "name": "Wei Liu"}, {"authorId": "2109426371", "name": "Yuming Zhu"}, {"authorId": "2280872767", "name": "Hecheng Li"}, {"authorId": "2306157108", "name": "Hao Peng"}, {"authorId": "2306151844", "name": "Qingchen Wu"}, {"authorId": "2306761017", "name": "Weiyu Shen"}, {"authorId": "2247887524", "name": "Shun Xu"}, {"authorId": "2305770248", "name": "Quanren Zhang"}, {"authorId": "2254818954", "name": "Yongtao Han"}, {"authorId": "2146042442", "name": "Jie Wang"}, {"authorId": "7356047", "name": "Shugeng Gao"}], "url": "https://www.semanticscholar.org/paper/0417bcd4d2409a6d85b85ecee4c4344dc03a1acb", "_run_id": "buMeZoslXregRUNL9", "_dataset_id": "BxX2TqmQx6Xxlu4CI"}
{"paperId": "008cbfccda3a852da14368153759ef3a773d41d2", "title": "Monetary Policy and Inflation Targeting: The Effectiveness of Central Bank Interventions", "abstract": "Central banks throughout the world have adopted inflation targeting as their main policy goal in the last several decades, drastically altering monetary policy—a pillar of economic management. the complex interplay between monetary policy, central bank interventions and measures for controlling inflation, and the success or failure of inflation targeting as a whole. This research aims to shed light on the extent to which central bank operations impact inflation results and the larger economic environment by conducting a thorough review of empirical evidence, case studies, and theoretical frameworks.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle", "Review"], "venue": "International Journal for Research Publication and Seminar", "journal": {"name": "International Journal for Research Publication and Seminar"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://jrps.shodhsagar.com/index.php/j/article/download/536/527", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2307796680", "name": "Dimple Jain"}], "url": "https://www.semanticscholar.org/paper/008cbfccda3a852da14368153759ef3a773d41d2", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "6fb964661392ccd2c7a398cbe35ef05acf4a350f", "title": "ANALYSIS AND EVALUATION OF THE TRANSMISSION MECHANISM OF THE MONETARY POLICY OF THE CENTRAL BANK OF THE RUSSIAN FEDERATION IN TARGETING INFLATION", "abstract": null, "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Фундаментальные исследования (Fundamental research)", "journal": {"name": "Фундаментальные исследования (Fundamental research)"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://s.fundamental-research.ru/pdf/2024/5/43606.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "1726557752", "name": "E. Vitsko"}, {"authorId": "2249666591", "name": "T. A. Yakovleva"}, {"authorId": "2304089248", "name": "V. P. Maryanenko"}], "url": "https://www.semanticscholar.org/paper/6fb964661392ccd2c7a398cbe35ef05acf4a350f", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "39928a0ad474a40914cb2a949d4307c04c75b98e", "title": "Monetary Policy Challenges and Central Bank Independence in Uzbekistan’s Inflation Targeting Transition", "abstract": "This article examines second language learning ability by analyzing second language development. It also examines the age factor in learning a language other than the mother tongue and attempts to clarify whether there is currently sufficient evidence to show that young people undergo real changes in their language skills.. Research such as inspiration for the learning climate, as well as exposure and behavior in the language will also be addressed and data analyzed to assess if they play an essential role in encouraging students to achieve effective second language skills. It was widely known to create a big improvement in language learning when you are young to study a second language. However, the findings show that this is not completely applicable in all situations, provided that other considerations such as language sensitivity and enthusiasm influence the effective accomplishment of second-language learning. If vocabulary is lacking, therefore this could discourage students from studying the language effectively. However, it is worth noting that factors such as motivation and exposure play a more important role in the learning stage than the aging factor. This empowers the learner because, regardless of his age, it is extremely important for him to be motivated enough and have enough language exposure from the beginning. \nHighlights: \n \nAnalyzes second language development and age factor in language learning. \nHighlights motivation, exposure, and behavior's impact on effective language skills. \nMotivation and exposure outweigh age in successful second-language acquisition. \n \nKeywords: Uzbekistan, Inflation Targeting, Monetary Policy, Central Bank Independence, Monetary Policy Transmission, Financial System Health", "year": 2024, "publicationDate": "2024-12-20", "publicationTypes": ["JournalArticle"], "venue": "Academia Open", "journal": {"name": "Academia Open"}, "citationCount": 0, "referenceCount": 4, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.21070/acopen.9.2024.10421", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Linguistics", "source": "s2-fos-model"}, {"category": "Education", "source": "s2-fos-model"}], "authors": [{"authorId": "5534989", "name": "U. Ganieva"}], "url": "https://www.semanticscholar.org/paper/39928a0ad474a40914cb2a949d4307c04c75b98e", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "af9ce7c86bb4c11e7827597fdbc915bf4de95d65", "title": "The Function and Effect of Artificial Intelligence (AI) in Central Bank Monetary Policy Decision Making, Inflation Prediction, and Economic Forecasting", "abstract": null, "year": 2024, "publicationDate": "2024-11-29", "publicationTypes": ["JournalArticle"], "venue": "International Research Journal of Education and Technology", "journal": {"name": "International Research Journal of Education and Technology"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.irjweb.com/The Function and Effect of Artificial Intelligence (AI) in Central Bank Monetary Policy Decision-Making, Inflation Prediction, and Economic Forecasting.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2359720464", "name": "Omkar Rajendra Nalla"}], "url": "https://www.semanticscholar.org/paper/af9ce7c86bb4c11e7827597fdbc915bf4de95d65", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "faeec72fae70e8281182da51ea2afaaa8b9d13a6", "title": "Hawkish shift in Ghana’s central bank’s monetary policy reaction function: a fiscal connection", "abstract": "ABSTRACT This study examines Ghana’s central bank’s monetary policy under Ghana’s inflation-targeting (IT) monetary policy regime since 2002. We find that Ghana’s central bank pursued a passive monetary policy under the unofficial IT monetary policy regime and hence cannot explain the decline in Ghana’s inflation rate during this period. We also find that Ghana’s central bank switched its monetary policy from passive to active under the official IT monetary policy framework, and hence cannot also explain Ghana’s rising inflation rate observed during this period. We provide evidence suggesting that Ghana’s central bank’s policy change might have been influenced by fiscal factors.", "year": 2024, "publicationDate": "2024-05-16", "publicationTypes": ["JournalArticle"], "venue": "Macroeconomics and Finance in Emerging Market Economies", "journal": {"name": "Macroeconomics and Finance in Emerging Market Economies", "pages": "149 - 175", "volume": "19"}, "citationCount": 1, "referenceCount": 31, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2121362799", "name": "Emmanuel Ameyaw"}], "url": "https://www.semanticscholar.org/paper/faeec72fae70e8281182da51ea2afaaa8b9d13a6", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "798e76f73e171170ce97ade0879d6759f24d9e12", "title": "THE IMPACT OF CENTRAL BANK DIGITAL CURRENCY (CBDC) VOLATILITY ON MONETARY POLICY EFFICIENCY IN FINANCIAL INCLUSION AND INVESTMENT", "abstract": "This paper explores the impact of Central Bank Digital Currency (CBDC) volatility on the efficiency of monetary policy, focusing on its role in financial inclusion and investment. As the world increasingly embraces digital currencies, central banks are exploring the potential benefits and risks associated with CBDCs. Volatility in CBDCs may have significant implications for the effectiveness of monetary policy, potentially influencing inflation control, interest rates, and economic stability. Moreover, CBDCs' introduction could either enhance or hinder financial inclusion by providing new opportunities for unbanked populations or exacerbating existing disparities. The paper reviews existing literature on CBDCs, highlighting key findings on their volatility and its effects on policy formulation. Furthermore, it assesses how volatility may impact investment decisions, both in terms of risk perception and market behavior. By examining the intersection of monetary policy, financial inclusion, and investment, this paper aims to provide a comprehensive understanding of CBDCs' potential in shaping modern economies. It is critical for policymakers to consider the dynamic nature of CBDC volatility when designing strategies for effective financial inclusion and sustainable investment. The paper concludes by identifying gaps in the current literature and proposing future research directions to further explore CBDC's impact on global economic systems. Ultimately, this review underscores the importance of mitigating volatility to maximize CBDCs' benefits in fostering inclusive economic growth.", "year": 2024, "publicationDate": "2024-11-27", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Social Economics Research", "journal": {"name": "Journal of Social and Economics Research"}, "citationCount": 1, "referenceCount": 63, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://idm.or.id/JSER/index.php/JSER/article/download/659/498", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2332853264", "name": "Eva Novita Pratiwi"}], "url": "https://www.semanticscholar.org/paper/798e76f73e171170ce97ade0879d6759f24d9e12", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "d24c44c4dd046957cf086d438af888ea18891027", "title": "Navigating Ghana’s monetary policy evolution and the potential of central bank digital currencies", "abstract": "This study investigates the evolution of monetary policy in Ghana and explores the potential of Central Bank Digital Currencies (CBDCs), specifically the e-Cedi, as a tool to enhance financial inclusion and modernize the country’s financial system. Ghana’s monetary policy framework has undergone significant transformations since the establishment of the Bank of Ghana in 1957, with notable achievements in stabilizing the economy and managing inflation. However, large segments of the population, particularly in rural areas, remain unbanked or underbanked, highlighting the limitations of traditional monetary tools. The introduction of the e-Cedi presents an opportunity to bridge these gaps by providing secure, efficient, and accessible financial services to underserved communities. The study employs a qualitative research design, integrating historical analysis, case studies, and thematic analysis to assess the potential benefits and challenges of CBDCs in Ghana. Key findings indicate that while the e-Cedi could significantly enhance financial inclusion, challenges related to technological infrastructure, cybersecurity, and public trust must be addressed. The study concludes that a balanced approach, which prioritizes digital infrastructure development, strong cybersecurity measures, and collaboration with financial institutions, is essential for maximizing the potential of CBDCs in Ghana. Recommendations for future research include a deeper exploration of the impact of CBDCs on financial stability and further analysis of rural adoption barriers.", "year": 2024, "publicationDate": "2024-11-15", "publicationTypes": ["JournalArticle"], "venue": "Journal of Infrastructure Policy and Development", "journal": {"name": "Journal of Infrastructure, Policy and Development"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://systems.enpress-publisher.com/index.php/jipd/article/download/8236/4658", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2281891180", "name": "Lóránt Dénes Dávid"}, {"authorId": "2328877822", "name": "Sewornu Kobla Afadzinu"}], "url": "https://www.semanticscholar.org/paper/d24c44c4dd046957cf086d438af888ea18891027", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "ace426c39373477534fb427aee277730265d888a", "title": "Considerations on the Monetary Policy Framework of the European Central Bank", "abstract": "This working paper offers some considerations on the monetary policy framework of the European Central Bank. The trade-offs arising from adopting a point target configuration over a range target one are assessed in terms of their flexibility vs. inflation anchoring properties. This layout is then confronted with the policy framework in use in the euro area prior to the adoption of the new monetary strategy, which is interpreted as leaning on the side of flexibility. The increased likelihood of dis-anchoring of long-term inflation expectations experienced in the euro area since 2013, however, suggests that the policy framework could benefit from a rebalancing towards a formulation with stronger anchoring properties. The inflation aim of the ECB could thus be reformulated with the introduction of a symmetric 2%-point target. By evaluating this arrangement in terms of the price stability definition, two regions emerge where either the policy aim (symmetric 2%-point target) or the price stability definition (between 0% and 2%) are satisfied, but not both. To avoid any inconsistency in the policy framework, an inflation aim centred at 2% requires an amendment of the price stability definition. JEL Classification: E42, E52, E58", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Social Science Research Network", "journal": {"name": "SSRN Electronic Journal"}, "citationCount": 0, "referenceCount": 95, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.econstor.eu/bitstream/10419/268293/1/1787059359.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "121473872", "name": "Andrea Tosato"}], "url": "https://www.semanticscholar.org/paper/ace426c39373477534fb427aee277730265d888a", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "10d6c53c4aeec18b3bce8fb7a5ca47deb744b9af", "title": "linear approach to estimating the impact of the central bank independence on the effectiveness of monetary policy in Algeria for the period (1990–2021)", "abstract": "Theoretically, delegating monetary policy to a central bank independent of political interference leads to lower inflation. In this paper, we empirically study the impact of central bank independence on the effectiveness of monetary policy (in achieving price stability) in Algeria for the period (1990–2021), using the ARDL model. Our results suggest that central bank independence and democracy have a significant negative impact on inflation. Moreover, we find that the term interaction (between CBI and democracy) has the strongest impact (negative significant) on inflation. The findings support the hypothesis that improving democracy will increase CBI degrees and boost the effectiveness of monetary policy in Algeria.", "year": 2024, "publicationDate": "2024-12-01", "publicationTypes": ["JournalArticle"], "venue": "Les cahiers du cread", "journal": {"name": "les cahiers du cread"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.ajol.info/index.php/cread/article/download/282520/267266", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2045250590", "name": "Abderrezak Madouri"}], "url": "https://www.semanticscholar.org/paper/10d6c53c4aeec18b3bce8fb7a5ca47deb744b9af", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "d2b8b0e3d5c1d0220585f95d379d0424372f9c61", "title": "Anti-crisis purpose of the monetary policy instruments of the Central bank of Russia", "abstract": "Introduction. The article examines the anti-crisis orientation of the instruments used by the Central Bank of the Russian Federation in order to stabilize the national economy in 2023 and achieve the target inflation rate of 4% in 2024. Goal. The article is devoted to the study of the problems of the functioning of the financial system of the Russian Federation during the period of sanctions pressure from the United States and EU countries. Materials and methods. The study is based on the consideration of theoretical and applied aspects of monetary policy pursued by the Central Bank of the Russian Federation in the context of the economic crisis that began in February 2022. The methodology of the study of the problems of interaction between the Central Bank of the Russian Federation and financial institutions is characterized by an integrated approach to assessing its results, which change under the influence of the unfriendly behavior of these countries in monetary policy and other information sources. Results and discussion. The article proves that the increase in inflation in Russia was caused by the crisis that arose due to the economic sanctions of the EU and the United States applied to our country, as well as an imbalance in the supply and demand of funds in the domestic market of working capital. This state of affairs requires the timely use of effective monetary policy instruments of the Central Bank of Russia. The proposals for the implementation of the monetary policy of the Russian Federation in the situation of deviation of the inflation rate from its target value are presented. Conclusion. The conclusions and generalizations of the study can be used to develop strategies that help offset the negative consequences of the global crisis and return the Russian economy to the basic scenario of its development, taking into account the target inflation rate of 4%. The scientific significance of the article lies in the theoretical understanding of the anti-crisis orientation of the monetary policy instruments pursued by the Central Bank of the Russian Federation in the sanctions environment. The practical significance of the study lies in the fact that its provisions can be used in the process of developing programs for the development of the financial system of the Russian Federation.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Вестник Северо-Кавказского федерального университета", "journal": {"name": "Вестник Северо-Кавказского федерального университета"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://vestnikskfu.elpub.ru/jour/article/download/2672/2579", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2133082396", "name": "V. A. Bredikhina"}], "url": "https://www.semanticscholar.org/paper/d2b8b0e3d5c1d0220585f95d379d0424372f9c61", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "e0ac779e184d173777a9077c8dd205ac05b52639", "title": "Effectiveness of Institutional Monetary Instruments at the Disposal of the Polish Central Bank (NBP). Experiences of the NBP’s Two Years of Struggle Against Inflation", "abstract": "The aim of the article is to attempt to answer three research questions: Was it inevitable that inflation would reach such a high (peak and cumulative) level in Poland? Can the fall in the level of inflation in Poland to the level of the European Union average be considered a real and sustainable success of NBP actions? In the struggle with inflation, did the NBP use all the institutional monetary instruments at its disposal? Methodology: The following methodological assumptions were adopted in the process of presentation, analysis and assessment of institutional monetary instruments. Firstly, as a methodological research requirement, I adopted the recommendation (method of analysis) of Kenneth J. Arrow, according to which analysis of the flow of money provides more information than any other analysis. Secondly, I assessed only the effectiveness of monetary policy instruments in accordance with the methodological assumption, according to which the veracity of statements (the applied monetary instruments) only makes sense in the context of the adopted assumptions (the causes of inflation), whose a priori falsehood determines the falsehood of theories or models (the effectiveness of combatting inflation). Results: The article conducts an analytical and synthetic assessment of the effectiveness of institutional monetary instruments used by the NBP. Implications and recommendations: The analysis provides the basis for presenting recommended changes to the strategy for combatting inflation in the future. Originality/Value: Author’s critical analysis of the effectiveness of the NBP’s use of monetary instruments in the fight against inflation.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Ekonomia XXI Wieku", "journal": {"name": "Ekonomia XXI Wieku"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://dbc.wroc.pl/Content/131249/Misinski_Effectiveness_of_Institutional_Monetary_Instruments.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2344493172", "name": "Wojciech Misiński"}], "url": "https://www.semanticscholar.org/paper/e0ac779e184d173777a9077c8dd205ac05b52639", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "a02906caa273e9a28f7dbc9d5fe2e22d40e58f10", "title": "Account of the monetary policy meeting of the Governing Council of the European Central Bank held in Frankfurt am Main on Wednesday and Thursday, 26-27 July 2023", "abstract": null, "year": 2023, "publicationDate": null, "publicationTypes": [], "venue": null, "journal": null, "citationCount": 10, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [], "url": "https://www.semanticscholar.org/paper/a02906caa273e9a28f7dbc9d5fe2e22d40e58f10", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "8723d84e14cbf586fbfcb0ad4b1bb6d680dd2c4e", "title": "INFLATION TARGETING AND POLICY DIVERGENCE: AN ANALYSIS OF CENTRAL BANK RESPONSES TO GLOBAL ECONOMIC UNCERTAINTY", "abstract": "Inflation targeting has emerged as a pivotal strategy in central banking, particularly in the face of global economic uncertainty. This study examines the responses of the Reserve Bank of India (RBI), the Federal Reserve System (Fed) in the United States, and the Central Bank of Bangladesh to the challenges posed by fluctuating global economic conditions. By analyzing monetary policy decisions, inflation trends, and economic outcomes in these three countries, the research highlights the divergence in central bank strategies despite a shared objective of maintaining price stability. The findings reveal that while the RBI and the Fed have adopted more flexible approaches, often adjusting inflation targets in response to domestic and international pressures, the Central Bank of Bangladesh has adhered to a more rigid framework. This divergence underscores the complex interplay between global economic forces and domestic policy objectives. The study’s implications suggest that central banks need to continuously adapt their strategies to account for both global uncertainties and domestic economic realities. Future research could explore the long-term effects of these divergent strategies on economic growth and financial stability, as well as investigate how emerging markets can enhance their resilience to external shocks while pursuing inflation targeting.", "year": 2024, "publicationDate": "2024-06-30", "publicationTypes": ["JournalArticle"], "venue": "ShodhKosh Journal of Visual and Performing Arts", "journal": {"name": "ShodhKosh: Journal of Visual and Performing Arts"}, "citationCount": 0, "referenceCount": 27, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.granthaalayahpublication.org/Arts-Journal/ShodhKosh/article/download/4456/4025", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2349256156", "name": "M M Munshi"}, {"authorId": "48735806", "name": "Keerti Deshpande"}], "url": "https://www.semanticscholar.org/paper/8723d84e14cbf586fbfcb0ad4b1bb6d680dd2c4e", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "58a939ca9826a159b7c73f075683b8e014510bb2", "title": "Can Central Bank Credibility Improve Monetary Policy? A Meta-Analysis", "abstract": "We bring together the largest meta-analysis ever conducted in the macroeconomic literature to investigate the effects of central bank credibility on monetary policy. With nearly 1,200 surveyed effects, we first confirm that: (i) conventional policy significantly affects inflation and output, and (ii) unconventional policy significantly affects capital flows and the exchange rate. We next evaluate if different measures of credibility amplify these effects. Our findings indicate that central bank transparency has the largest payoff, as it increases policy effectiveness by 69% when dealing with foreign exchange intervention, by 59% when dealing with capital inflows, and by 14% when dealing with conventional policy. An alternative measure, medium and long-term anchoring in inflation expectations, is the runner up, increasing effectiveness by 31%, 9%, and 10%, respectively. Other measures, such as central bank independence and short-term anchoring in inflation expectations have lower and in some cases null effects.", "year": 2023, "publicationDate": "2023-06-16", "publicationTypes": ["CaseReport", "JournalArticle", "Review"], "venue": "International Finance", "journal": {"name": "International Finance"}, "citationCount": 8, "referenceCount": 45, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.32468/be.1239", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2282541673", "name": "Valentina Cepeda"}, {"authorId": "2221749239", "name": "Bibiana Taboada-Arango"}, {"authorId": "1404747594", "name": "Mauricio Villamizar-Villegas"}], "url": "https://www.semanticscholar.org/paper/58a939ca9826a159b7c73f075683b8e014510bb2", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "c2f47925e60bb811409489574637b0ec87021e33", "title": "Distinguished fellow lecture: monetary policy and the benefits and limits of central bank independence", "abstract": "Central bank independence is an important development in macroeconomics. It has become a lynchpin of modern central banking. The period since the Global Financial Crisis and the experience of the COVID-19 pandemic era posed new challenges for central banks, with potential implications for central bank independence. This paper reviews the scope and rationale for central bank independence and the reasons it spread internationally after the 1980s. It reviews evidence of the effects of central bank independence on inflation, output volatility, financial stability and fiscal policy. The paper considers political threats and contemporary policy issues that could influence the form of central bank independence and credibility. These issues include matters relating to assessments of monetary policy during the pandemic, the scope of central bank mandates, interpretations of inflation dynamics, the funding of central bank operations, and the interaction between fiscal and monetary policy.", "year": 2023, "publicationDate": "2023-09-02", "publicationTypes": ["JournalArticle", "Review"], "venue": "New Zealand Economic Papers", "journal": {"name": "New Zealand Economic Papers", "pages": "263 - 289", "volume": "57"}, "citationCount": 2, "referenceCount": 184, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Political Science", "source": "s2-fos-model"}], "authors": [{"authorId": "4763357", "name": "R. Buckle"}], "url": "https://www.semanticscholar.org/paper/c2f47925e60bb811409489574637b0ec87021e33", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "58930941086e16349ded24902463de7a766f43f8", "title": "Meeting of 9-10 March 2022 Account of the monetary policy meeting of the Governing Council of the European Central Bank held in Frankfurt am Main on Wednesday and Thursday, 9-10", "abstract": null, "year": 2023, "publicationDate": null, "publicationTypes": ["Review"], "venue": null, "journal": null, "citationCount": 0, "referenceCount": 1, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [], "url": "https://www.semanticscholar.org/paper/58930941086e16349ded24902463de7a766f43f8", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "e8e3dc1b93c1fafc77a5d94e374deff31f1a27bc", "title": "Beware of Pitfalls in the European Central Bank’s Review of Monetary Policy Strategy", "abstract": "Abstract The long-awaited Review of Monetary Policy Strategy of the European Central Bank has been released. According to the Governing Council, “price stability is best maintained by aiming for 2% inflation over the medium term”, with “symmetric commitment” to this target. “Symmetry means that the Governing Council considers negative and positive deviations from this target as equally undesirable”. This orientation seems contrarian to the view, expressed by some dissenting scholars, that 2% should be set as a ceiling, and that persistent inflation below 2% observed over the last decade was to be adopted as the “new normal”. The aim of this paper is not to examine and assess the new policy strategy of the ECB per se, but to warn about pitfalls in detecting undesirable (expectation-driven) deviations of inflation from target versus permanent changes in the ouput-inflation relationship.", "year": 2022, "publicationDate": "2022-03-10", "publicationTypes": ["Review"], "venue": "The Economists' Voice", "journal": {"name": "The Economists’ Voice", "pages": "15 - 23", "volume": "19"}, "citationCount": 3, "referenceCount": 16, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.degruyter.com/document/doi/10.1515/ev-2021-0024/pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "70032240", "name": "R. Tamborini"}], "url": "https://www.semanticscholar.org/paper/e8e3dc1b93c1fafc77a5d94e374deff31f1a27bc", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "67efa78fed4b45be9c48a0d30b752030777cbbfc", "title": "Macroeconomics Adjustments in Southeast Asia: Inflation, Monetary Policy, and Economic Resilience", "abstract": "This paper analyzes macroeconomic adjustments in Southeast Asia, emphasizing inflation dynamics, monetary policy, and economic resilience in ASEAN countries. Inflation, propelled by supply chain disruptions, fluctuating commodity prices, and global economic shocks, impedes economic progress and diminishes household purchasing power throughout the region. The research employs a mixed-methods approach to analyze data from ASEAN central banks, World Bank, and IMF reports, investigating the relationship between inflation trends, economic growth, and monetary and fiscal actions. Findings indicate modest inflation stability in Indonesia and Malaysia, in contrast to pronounced inflationary surges in Lao PDR and Myanmar, which impede growth and diminish buying power. Adaptive monetary policies, exemplified by Malaysia’s exchange rate systems, alongside fiscal measures like targeted subsidies in Vietnam, have demonstrated efficacy in controlling inflation and enhancing resilience. Nonetheless, structural inefficiencies and regional inequities endure, underscoring the necessity for coordinated ASEAN policies. The results correspond with current literature, highlighting inflation-targeting frameworks and monetary independence but revealing distinct issues in nations with limited economic diversification. This report advocates for more regional collaboration, flexible monetary policies, and economic diversification to secure sustained growth and stability in the face of changing global challenges. The results inform policymaking initiatives for sustainable economic development in Southeast Asia.", "year": 2024, "publicationDate": "2024-12-30", "publicationTypes": ["JournalArticle"], "venue": "Global Journal of Humanities and Social Sciences Research", "journal": {"name": "Global Journal of Humanities and Social Sciences Research"}, "citationCount": 2, "referenceCount": 32, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [], "url": "https://www.semanticscholar.org/paper/67efa78fed4b45be9c48a0d30b752030777cbbfc", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "8c025a259bb7db75e0275b32285e38d53aa63264", "title": "Monetary Policy and Inflation Dynamics in Nigeria: A Bayesian DSGE Approach", "abstract": "This study examines monetary policy shock and inflation dynamics in Nigeria within an open economy Bayesian DSGE model framework, employing data from 2000Q1 to 2023Q1. It applies different price measures across the pre-COVID/Russia-Ukraine war era and the entire sample. Findings reveal a significant impact of monetary policy shock on inflation, irrespective of the price measure adopted. Remarkably, the results also reveal a marginal decline in the potency of monetary policy in the COVID/Russisa-Ukraine War era, compared to the pre- COVID/Russisa-Ukraine War era. The study recommends the adoption of GDP deflator as the measure of inflation that anchors inflation expectations as it is most responsive to monetary policy innovations. It also recommends complementing monetary policy with supply-side policies when faced with inflationary pressures occasioned by supply chain disruptions.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Central Bank of Nigeria Journal of Applied Statistics", "journal": {"name": "Central Bank of Nigeria Journal of Applied Statistics"}, "citationCount": 3, "referenceCount": 27, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://dx.doi.org/10.33429/cjas.01024.5/7", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "119520391", "name": "M. Adebiyi"}, {"authorId": "120029524", "name": "E. Adamgbe"}, {"authorId": "2190344479", "name": "A. Odu"}], "url": "https://www.semanticscholar.org/paper/8c025a259bb7db75e0275b32285e38d53aa63264", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "0a3a09faa3c577283d5b0c4658821edfd9e00790", "title": "Inflation Disagreement Weakens the Power of Monetary Policy", "abstract": "Households often disagree in their inflation outlooks. We present novel empirical evidence that inflation disagreement weakens the power of forward guidance and conventional monetary policy. These empirical observations can be rationalized by a model featuring heterogeneous beliefs about the central banks’ inflation target. An agent who perceives higher future inflation also perceives a lower real interest rate and thus would like to borrow more to finance consumption, subject to borrowing constraints. Higher inflation disagreement would lead to a larger share of borrowing-constrained agents, resulting in more sluggish responses of aggregate consumption to changes in both current and expected future interest rates. This mechanism also provides a microeconomic foundation for Euler equation discounting that helps resolve the forward guidance puzzle.", "year": 2024, "publicationDate": "2024-08-08", "publicationTypes": ["JournalArticle"], "venue": "Federal Reserve Bank of San Francisco, Working Paper Series", "journal": {"name": "Federal Reserve Bank of San Francisco, Working Paper Series"}, "citationCount": 3, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frbsf.org/wp-content/uploads/wp2024-27.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2143654785", "name": "Dingrui Dong"}, {"authorId": "2272803111", "name": "Zheng Liu"}, {"authorId": "2233983964", "name": "Pengfei Wang"}, {"authorId": "2072846682", "name": "Min Wei"}], "url": "https://www.semanticscholar.org/paper/0a3a09faa3c577283d5b0c4658821edfd9e00790", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "3c0638bd0c672e345bff7ac2e91de8b0c65b8a21", "title": "Does Central Bank Transparency Matter for Inflation: Role of Inflation Targeting", "abstract": "This paper examines the relationship between central bank transparency and inflation for six inflation targeting (IT) and ten non-inflation targeting (non-IT) Asian economies. The propensity score matching and panel regression model are employed in the study. The empirical analysis shows that IT enhances central bank transparency. Further, we find that central bank transparency in IT significantly lowers inflation, suggesting that countries promoting greater monetary policy transparency can have a better advantage of experiencing low inflation. Our findings have policy implications for central banks in developing economies that are grappling with low transparency", "year": 2024, "publicationDate": "2024-07-19", "publicationTypes": ["JournalArticle"], "venue": "Journal of Economic Integration", "journal": {"name": "Journal of Economic Integration"}, "citationCount": 3, "referenceCount": 71, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.e-jei.org/upload/jei-2024031.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "122731939", "name": "Dinabandhu Sethi"}, {"authorId": "24349256", "name": "D. Acharya"}, {"authorId": "2306942775", "name": "Ujjwal Sharma"}], "url": "https://www.semanticscholar.org/paper/3c0638bd0c672e345bff7ac2e91de8b0c65b8a21", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "dee0f5ea32f070874014ca9c957274a185381e08", "title": "Central Bank Independence and Inflation Under Asymmetric Information: Delegation vs. Seesaw Effects", "abstract": "Abstract Recent empirical research finds little or mixed evidence in favour of a negative relationship between central bank independence and inflation. In this paper, we construct a theory where the relationship between inflation and central bank independence depends on the extent of informational asymmetry regarding the government’s efficiency in its provision of public goods and also provide some empirical support for it. In the theoretical part of the paper, we introduce the degree of central bank independence as a fixed cost that is paid when the government (whose objective is to minimize output gap via inflation or costly fiscal expansion) rejects the monetary policy proposal of the central bank (which aims to minimize inflation) and determines both fiscal and monetary policies itself. Government efficiency in providing public goods, i.e. the cost of fiscal expansion, is the private information and the source of informational asymmetry in our model. In this setting, increasing the fixed cost of rejecting the central bank’s offer creates two opposite effects on inflation: delegation effect and seesaw effect (since fiscal and monetary expansion are substitutes for the government, now it relies more on fiscal expansion). We show that while the magnitude of the delegation effect is equal to or higher than the seesaw effect, the magnitude of each effect depends on the current level of the fixed cost. If the current fixed cost is not high enough, then a small improvement in central bank independence creates a relatively smaller delegation effect compared to the case where fixed cost is high enough and both efficient and inefficient government types accept the offer.", "year": 2024, "publicationDate": "2024-09-01", "publicationTypes": ["JournalArticle"], "venue": "Journal of Central Banking Theory and Practice", "journal": {"name": "Journal of Central Banking Theory and Practice", "pages": "245 - 270", "volume": "13"}, "citationCount": 2, "referenceCount": 40, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.2478/jcbtp-2024-0029", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "50815352", "name": "C. Elgin"}, {"authorId": "2045254363", "name": "Oğuz Öztunalı"}], "url": "https://www.semanticscholar.org/paper/dee0f5ea32f070874014ca9c957274a185381e08", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "636403f22a0f4f3518f84d0df243ac4259f7ab61", "title": "Determination of the effects and optimal thresholds of monetary policy instruments: A study of Central Bank Lending system in Kingdom of Eswatini", "abstract": "Abstract This paper examines the impact of monetary policy instruments such as discount rate, reserve requirement and liquidity requirement on bank credit to the private sector in the Kingdom of Eswatini. Monthly data sourced from the Central Bank of Eswatini and Eswatini Central Statistics Office is used for the period January 2000 to December 2017. Using the Johansen cointegration test and Vector Error Correction Model, our results show that: there is one cointegration in the model and the current levels of the discount rate, reserve requirement and liquidity requirement bear a negative and significant effect to bank credit to the private sector. This indicates that the three instruments are not supportive to economic growth and they are not optimal to stimulate credit. Applying the Quadratic approach, findings of this study reveal that the optimal monetary policy mix (thresholds) to stimulate bank credit to the private sector while maintaining inflation within reasonable levels is 5.42% for the discount rate, 4.03% for the reserve requirement, 12.48% for the liquidity requirement. The study recommends that the Central Bank of Eswatini should always take into account the existence of trade-off in monetary policy instruments results in order to stimulate bank lending to the private sector.", "year": 2022, "publicationDate": "2022-12-31", "publicationTypes": [], "venue": "Cogent Economics &amp; Finance", "journal": {"name": "Cogent Economics & Finance", "volume": "11"}, "citationCount": 0, "referenceCount": 44, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1080/23322039.2022.2160582", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2199097552", "name": "Samuel Nkosinathi Dlamini"}, {"authorId": "2199100939", "name": "Dr Pfano Mashau"}], "url": "https://www.semanticscholar.org/paper/636403f22a0f4f3518f84d0df243ac4259f7ab61", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "3d3a7bfe19547adbab24f5093ea09d7a3589733d", "title": "The Effect Of Monetary Policy On Economic Growth In Mogadishu Somalia, Case Study Central Bank Of Somalia", "abstract": null, "year": 2022, "publicationDate": null, "publicationTypes": [], "venue": null, "journal": null, "citationCount": 0, "referenceCount": 4, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "7548725", "name": "Farhana Ali"}], "url": "https://www.semanticscholar.org/paper/3d3a7bfe19547adbab24f5093ea09d7a3589733d", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "dcda21be4e20296e92103f21e731535af619c41b", "title": "Why the European Central Bank lacked efficacy to fight against the recent surge in inflation", "abstract": "The paper focuses on the determinants of the surge in inflation between 2021 and 2023 and on the efficacy of monetary policy in fighting against these inflationary tensions. The main role of the European Central Bank is to ensure that inflation expectations remain anchored to a clear target. An active monetary policy can also stabilize future expected inflationary tensions or demand shocks. However, a simple theoretical model can explain the incapacity of European monetary policy to fight against the supply-side factors of inflation in the post-COVID period: inflationary tensions inherited from previous periods, imported from foreign countries (energy and food), or due to higher current or anticipated profit margins. In these cases, a huge increase in the nominal interest rate and a very contractionary monetary policy only risk creating a strong recession, without avoiding inflationary tensions.", "year": 2024, "publicationDate": "2024-12-13", "publicationTypes": ["JournalArticle"], "venue": "Forum for Economic and Financial Studies", "journal": {"name": "Forum for Economic and Financial Studies"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://ojs.acad-pub.com/index.php/FEFS/article/download/1626/1092", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "78156990", "name": "S. Menguy"}], "url": "https://www.semanticscholar.org/paper/dcda21be4e20296e92103f21e731535af619c41b", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "7af2a9d5f0e61c3d9d3c1c7859c53e659bd15c66", "title": "CENTRAL BANK INDEPENDENCE, INFLATION AND VOLATILITY NEXUS: DOES INDEPENDENCE CAN SOLVE INFLATION?", "abstract": "In this study, the relationship between central bank independence and both inflation rate and inflation uncertainty is examined with the help of panel data analysis for BRICS-T countries, using data for the period 1995-2017. The findings reveal several notable results. First, the study finds a statistically significant and negative relationship between the level of central bank independence and inflation in BRICS-T countries. Consequently, this means that a higher degree of independence is associated with lower inflation rates. Additionally, the study reveals a statistically significant and positive relationship between central bank independence and inflation uncertainty. This shows that inflation uncertainty tends to increase as the level of independence increases. These results shed light on the complex dynamics between central bank independence, inflation, and inflation uncertainty, providing valuable information for policymakers, central banks, and researchers interested in monetary policy effectiveness and macroeconomic stability. It is recommended that future studies investigate the underlying mechanisms driving these relationships and evaluate potential differences across countries and time periods", "year": 2024, "publicationDate": "2024-09-01", "publicationTypes": ["JournalArticle", "Conference"], "venue": "Proceeding of the World Conference on Management, Business, and Finance", "journal": {"name": "Proceeding of the World Conference on Management, Business, and Finance"}, "citationCount": 1, "referenceCount": 24, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.dpublication.com/conference-proceedings/index.php/worldmbf/article/download/544/384", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "152234819", "name": "D. Yıldırım"}, {"authorId": "2319150902", "name": "İbrahim Güran Yumuşak"}, {"authorId": "2319149274", "name": "İ. Aksu"}], "url": "https://www.semanticscholar.org/paper/7af2a9d5f0e61c3d9d3c1c7859c53e659bd15c66", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "9024a6647362630da82e8762a3f7097b2bc2c324", "title": "Central bank balance sheet and inflation in a euroised small open economy: a cointegrated SVAR analysis", "abstract": "The Bank of Albania has not employed traditional balance sheet policies; however, it has taken a series of policy actions that have increased the proportion of non-borrowed relative to borrowed components of the monetary base and its balance sheet liabilities. We aim to investigate whether these changes in the structure of the central bank balance sheet gave rise to additional monetary shocks with direct effects on inflation. The hypothesis is tested by estimating a small structural VAR model with cointegrated I(1) and I(0) policy and non-policy variables. We identify long-run restrictions based on the embedded structure of the data generating process, as defined by cointegration relationships. Our findings suggest that an increase in the share of non-borrowed components of the monetary base has direct and indirect positive effects on inflation. We argue that the identification of this monetary shock has significant implications for the central bank and its monetary policy.", "year": 2024, "publicationDate": "2024-12-13", "publicationTypes": ["JournalArticle"], "venue": "Public Sector Economics", "journal": {"name": "Public Sector Economics"}, "citationCount": 1, "referenceCount": 22, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.3326/pse.48.4.6", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "101844139", "name": "Gent Sejko"}, {"authorId": "117875663", "name": "Altin Tanku"}], "url": "https://www.semanticscholar.org/paper/9024a6647362630da82e8762a3f7097b2bc2c324", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "f768e44c37b021ec2c0536def145953746ba7596", "title": "Inflation-Targeting Monetary Policy Framework in Nigeria: The Success Factors", "abstract": "Many developing countries are facing high inflation and the central bank in these countries have adopted several solutions to tame rising inflation. Nigeria transitioned to an inflation targeting monetary policy framework in late 2023 from a monetary targeting monetary policy framework. This study identifies the important success factors for an effective inflation targeting monetary policy regime in Nigeria. The identified success factors include the size or number of economic agents monitoring the inflation target, the credibility of the central bank, the degree of central bank independence, reduction in budget deficit, limited dollarization of the Nigerian economy, effective central bank communication, avoidance of fiscal dominance, financial development, greater financial inclusion, financial stability", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Social Science Research Network", "journal": {"name": "SSRN Electronic Journal"}, "citationCount": 3, "referenceCount": 4, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://mpra.ub.uni-muenchen.de/120775/1/MPRA_paper_120775.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "113773639", "name": "Peterson K. Ozili"}], "url": "https://www.semanticscholar.org/paper/f768e44c37b021ec2c0536def145953746ba7596", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "9601bdf5272f66dd3f350b5df43e1f6936d75ba4", "title": "Central Bank Independence and Monetary Stability in Hungary, 1920s and 1990s", "abstract": "This study compares monetary policy and inflation in Hungary in the first half of the 1920s and the first half of the 1990s. In both periods, economic and financial imbalances placed pressure on the central bank to provide inflationary finance. Eventually, in response to the resulting inflation, central bank independence was significantly strengthened. But while central bank independence helped, in neither case did it suffice to prevent subsequent instability. The central bank inevitably felt pressure to accommodate problems emanating from the banking sector, the balance of payments, the government budget and weakened sectors of the economy. The paper concludes by drawing out the implications for current legislation potentially affecting the independence of Hungary’s central bank.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Financial and economic review", "journal": {"name": "Financial and Economic Review"}, "citationCount": 0, "referenceCount": 21, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://hitelintezetiszemle.mnb.hu/sw/static/file/fer-23-4-st2-eichengreen.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2338613475", "name": "Barry Eichengreen"}], "url": "https://www.semanticscholar.org/paper/9601bdf5272f66dd3f350b5df43e1f6936d75ba4", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "2967c7ec89e304e6d633b46426969b4b9555a91d", "title": "Unconventional Monetary Policy Response to Covid-19 and Its Impact on Inflation in Morocco", "abstract": "This study explores the impact of unconventional monetary policy on Morocco’s economy during the Covid-19 pandemic. We used a hybrid model combining a financial dynamic stochastic general equilibrium (DSGE) model with a standard epidemiology model, enabling us to consider both economic and epidemiological factors. Our results indicate that unconventional monetary policy cannot fully mitigate the adverse effects of a pandemic, except for an exogenous increase in Central Bank claims. We also found that Morocco’s high inflation is partly due to Bank Al-Maghrib’s unconventional monetary measures in response to the pandemic. Our research underscores the importance of monetary authorities balancing the benefits and risks of unconventional monetary policy. While it can stimulate the economy during crises, it should be used judiciously to avoid long-term negative effects. Incorporating epidemiological factors into macroeconomic models is crucial for understanding the intricate interplay between the economy and public health crises.", "year": 2024, "publicationDate": "2024-09-13", "publicationTypes": ["JournalArticle"], "venue": "Statistika: Statistics and Economy Journal", "journal": {"name": "Statistika: Statistics and Economy Journal"}, "citationCount": 5, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.54694/stat.2024.8", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2260489338", "name": "Hicham Ouakil"}, {"authorId": "2260483620", "name": "Abdelhamid Moustabchir"}, {"authorId": "2274692959", "name": "Hicham El Ouazzani"}], "url": "https://www.semanticscholar.org/paper/2967c7ec89e304e6d633b46426969b4b9555a91d", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "fce369ed7e6189ef64ba4fef18a5d83648c64d8d", "title": "Examining Inflation Expectations within Asian Economies: Application of Wavelet Quantile Analysis towards Assessing Monetary Policy Credibility", "abstract": "The relevance of rational expectations has generated a renewed interest in assessing the accuracy of monetary policy declarations. Despite the enduring principles of the rational expectations theory, a remarkably dependable central bank can alleviate inflation by skillfully managing inflation expectations, thus avoiding adverse effects on employment. This paper explores the complex relationship between inflation expectations, target inflation rates, and the credibility of monetary policy, emphasizing the importance of rule compliance and transparent communication for establishing public confidence in central banks. While the estimation processes the study utilizes wavelet-based quantile regression by investigating data from 1990q1 to 2021q4, with variations across selected countries. The credibility index (CI) is employed to instrument the dependability of monetary policies. Nevertheless, the results of this study indicate that Policy credibility has a significant impact on inflation expectations in Bangladesh and Sri Lanka, underscoring the importance of clear communication and institutional reforms. Different outcomes in India and considerable effects in Pakistan underscore the necessity of customized policy measures and communication strategies to address inflation and promote economic stability in South Asia.", "year": 2024, "publicationDate": "2024-04-30", "publicationTypes": ["JournalArticle"], "venue": "Journal of economic impact", "journal": {"name": "Journal of Economic Impact"}, "citationCount": 1, "referenceCount": 41, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.scienceimpactpub.com/journals/index.php/jei/article/download/839/486", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2261843133", "name": "Khaliq ul Rehman"}, {"authorId": "2261844985", "name": "G. Ghouse"}], "url": "https://www.semanticscholar.org/paper/fce369ed7e6189ef64ba4fef18a5d83648c64d8d", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "916b518a23f24873a173370b89c44268c4a56b46", "title": "Monetary Policy and Inflation Targeting Framework in Indonesia Dual Banking System", "abstract": "Since 1990 the use of inflation as a nominal anchor used as the main target of monetary policy began to be an option for central banks in several countries. The new monetary policy framework is then known as Inflation Targeting Framework (ITF). This study tries to look at some important variables that affect the inflation rate within the framework of the Inflation Targeting Framework concept using Vector Error Correction Model. The results of data processing using VECM analysis can determine the behavior of Bank Indonesia Rate (BI Rate), Money Supply, Interbank Money Market (PUAB), Sharia Interbank Money Market (PUAS), and Sharia Bank Indonesia Certificates (SBIS). These variables significantly affect the inflation rate. The results of this study can provide important information for decision makers and academics as an evaluation of the application of ITF based on its application in Indonesia.", "year": 2024, "publicationDate": "2024-03-09", "publicationTypes": ["JournalArticle"], "venue": "Islamic Capital Market", "journal": {"name": "Islamic Capital Market"}, "citationCount": 2, "referenceCount": 24, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://journals.smartinsight.id/index.php/ICM/article/download/445/417", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2293015979", "name": "Izzan Maulana Saputra"}], "url": "https://www.semanticscholar.org/paper/916b518a23f24873a173370b89c44268c4a56b46", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "307af74d5ed2402dc83635dd2814d8ccfbd984d0", "title": "Investigating the Effectiveness of India’s Monetary Policy in Controlling Inflation and Maintaining Price Stability", "abstract": "This study examines how India’s monetary policy impacts inflation and contributes to price stability. Using\nsecondary data from sources like the IMF, RBI, and the World Bank, the research employs trend analysis and\nstatistical regression to establish a linear relationship between inflation and the bank rates set by the country's\ncentral bank. It specifically explores the connection between the repo rate and inflation. Given India’s large\ninformal sector, the study investigates the channels through which changes in interest rates, money supply, and\nbanking regulations influence the economy and affect price levels. Additionally, the research assesses the\neffectiveness of these tools under different economic conditions, such as periods of economic growth or recession.\nThe findings suggest that while the repo rate and central bank policies do impact inflation to some extent, other\neconomic factors also play a significant role. Therefore, implementing a robust monetary policy can help control\ninflation, stabilize prices, and foster overall economic growth.", "year": 2024, "publicationDate": "2024-12-10", "publicationTypes": ["JournalArticle"], "venue": "INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT", "journal": {"name": "INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2415687501", "name": "V. B"}, {"authorId": "2219592906", "name": "R. M"}, {"authorId": "2382871983", "name": "Vikram Patil"}, {"authorId": "2334759759", "name": "K. M"}], "url": "https://www.semanticscholar.org/paper/307af74d5ed2402dc83635dd2814d8ccfbd984d0", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "1989a2e3d54afcbd6f8b0b2e763e5f9971e7edff", "title": "Assessing the Impact of Sanctions and Central Bank Independence on Inflation Targeting in Iran", "abstract": "Price stability has long been a fundamental objective of monetary policy, with inflation targeting emerging as one of the most effective approaches in recent decades. This study examines the determinants of inflation targeting in the Iranian economy from 1979 to 2023. To comprehensively evaluate the effectiveness of inflation targeting in Iran, key factors such as inflation uncertainty, central bank independence, economic sanctions, transparency and accountability, money supply, minimum nominal wages, and exchange rates were analyzed. Central bank independence was first assessed and quantified using the Principal Component Analysis (PCA) method, followed by an examination of the factors influencing the discrepancy between the actual inflation rate and the target inflation rate. The findings indicate that central bank independence, exchange rates, and money supply exert a significant negative impact on the gap between actual and target inflation. In contrast, nominal minimum wages, economic sanctions, and inflation volatility contribute positively to this gap. These results suggest that achieving the target inflation rate necessitates establishing the appropriate conditions for the effective implementation of inflation-targeting policies. The government and the Central Bank of Iran, as well as policymakers in developing economies with similar economic structures, should adopt optimal policy measures to enhance the effectiveness of inflation targeting.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Business, Marketing, and Finance Open", "journal": {"name": "Business, Marketing, and Finance Open"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "84114812", "name": "A. Alikhani"}, {"authorId": "2214558983", "name": "Hossein Sharifi Renani"}, {"authorId": "1450813518", "name": "Saeed Daei-Karimzadeh"}], "url": "https://www.semanticscholar.org/paper/1989a2e3d54afcbd6f8b0b2e763e5f9971e7edff", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "76e0df0db2a3f703535b25c9b277c185be3ad2e8", "title": "THE ROLE OF THE EUROPEAN CENTRAL BANK IN THE MONETARY INTEGRATION OF EUROPEAN UNION MEMBER STATES", "abstract": "European Central Bank (ECB) is a financial institution of the European Union which influences the process of European integration to a large degree. The primary goal of the Bank is to maintain price stability within the Eurozone. The rate of inflation should be close to 2%. Other objectives are subordinate to the main objective. The most important tasks of the ECB include the implementation of the monetary policy for the Eurozone, conducting foreign exchange operations, and taking care of the foreign reserves of the European system. It has the exclusive right to issue euro banknotes and member states of the Eurozone can issue euro coins on authorization of the ECB. The Bank influences the level of life of EU citizens. The economic situation of the Eurozone, in turn, has an impact on support for the European integration on the part of EU citizens. ECB is a global player on financial markets allowing the EU to maintain its global status as an economic powerhouse. The aim of the paper is to present the status of the ECB and its role in the institutional system of the EU.", "year": 2024, "publicationDate": "2024-01-18", "publicationTypes": ["JournalArticle"], "venue": "Financial Internet Quarterly", "journal": {"name": "Financial Internet Quarterly"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://journals.wsiz.edu.pl/fiq/article/download/919/874", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Political Science", "source": "s2-fos-model"}], "authors": [{"authorId": "51357744", "name": "Małgorzata Paszkowska"}, {"authorId": "2101170710", "name": "Krzysztof Czubocha"}], "url": "https://www.semanticscholar.org/paper/76e0df0db2a3f703535b25c9b277c185be3ad2e8", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "1c0c26080d426d7ccc86e1ae72d71296ba3243f7", "title": "Central Bank Independence, Inflation and Money Growth: Evidence from South Africa", "abstract": "Purpose: This article evaluates the impact of the de jure independence of the South African Reserve Bank (SARB) on the credibility and discipline of domestic monetary policy. Credibility captures the extent to which economic agents trust the SARB to pursue its price stability mandate and is measured by the relationship between the SARB’s independence and domestic inflation. Discipline relates to the effect of independence on money growth rates, while independence is associated with a more disciplined central bank and moderate money growth rates.\nMethodology: A simple autoregressive distributed lag (ARDL) econometric specification and Granger causality tests are employed. Following the extant empirical literature, existing indexes of central bank independence (CBI) are regressed on annual rates of inflation and M2 money growth.\nFindings: A statistically significant negative relationship is established between both i) CBI and inflation and ii) CBI and money growth for the South African economy. This suggests that the SARB’s legal independence plays an important role in containing inflation (credibility) and limiting excessive money growth (discipline).\nContribution: This article fills a gap in the extant literature by being the first attempt at formalising the empirical link between de jure CBI, inflation, and the rate of money growth in the South African economy.", "year": 2024, "publicationDate": "2024-04-29", "publicationTypes": ["JournalArticle"], "venue": "Southern African Business Review", "journal": {"name": "Southern African Business Review"}, "citationCount": 0, "referenceCount": 40, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://unisapressjournals.co.za/index.php/SABR/article/download/14375/7622", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "145942292", "name": "C. Vermeulen"}], "url": "https://www.semanticscholar.org/paper/1c0c26080d426d7ccc86e1ae72d71296ba3243f7", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "065302d72d5e6c292e937c2d9ee3990a6a2dbbf2", "title": "CHANGING THE KEY INTEREST RATE AS A WAY OF MONETARY POLICY OF THE CENTRAL BANK OF RUSSIA", "abstract": "The current value of the key interest rate set by the Central Bank is analyzed, its impact on the inflation rate, on deposit and loan rates. The short-term forecast of the Central Bank on stabilization of the current situation is given", "year": 2022, "publicationDate": "2022-05-16", "publicationTypes": [], "venue": "Modern Technologies and Scientific and Technological Progress", "journal": {"name": "Modern Technologies and Scientific and Technological Progress"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://angtu.editorum.ru/en/storage/download/90740", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "1572384168", "name": "Elena Cheklaukova"}, {"authorId": "2138656008", "name": "Ol'ga Badmazhanova"}], "url": "https://www.semanticscholar.org/paper/065302d72d5e6c292e937c2d9ee3990a6a2dbbf2", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "7c3cff00f2165cedd1c9cf06ce11873f5153082e", "title": "Measuring AND Analyzing the Impact OF Monetary Policy Tools in Controlling Inflation Rates in Iraq for the Period 2004-2022", "abstract": null, "year": 2024, "publicationDate": "2024-04-08", "publicationTypes": [], "venue": null, "journal": {"name": "Galaxy International Interdisciplinary Research Journal", "pages": "157 - 171", "volume": "12"}, "citationCount": 0, "referenceCount": 7, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2253695632", "name": "H. Mahmood"}, {"authorId": "2328475438", "name": "Khalil Ismail Aziz"}], "url": "https://www.semanticscholar.org/paper/7c3cff00f2165cedd1c9cf06ce11873f5153082e", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "21aa163104216e2636eb930c1cea3a6c504ca84b", "title": "Fiscal Policy, Monetary Policy, and Growth: The Impact of Unemployment and Inflation on Growth in Saudi Arabia", "abstract": "This paper uses time-series regression analysis to investigate the long-run effect of fiscal and monetary policies on economic growth in Saudi Arabia from 1999 to 2022. Regarding fiscal policy, we focus on government spending and exclude taxes because the latter had not been used in the Kingdom as a fiscal tool during most of the study period. For monetary policy, we focus on money supply (i.e., open market operations) and exclude interest rate, because by following a fixed-exchange-rate policy to the US dollar, the Saudi Central Bank has lost some of its monetary independence to the Federal Reserve when it comes to setting interest rates. Our results show a statistically significant positive impact of government spending on economic growth and a statistically significant negative impact of unemployment on economic growth in the long run. Also, we find the effect of money supply and inflation on economic growth in the long run to be statistically insignificant. These results are consistent with economic theory and empirical research which show countries that follow a fixed-exchange-rate policy usually lose the effectiveness of their monetary policy. Finally, we recommend taking extra care not to overuse government spending as the only tool for growth: on one hand, government spending boosts growth and lowers unemployment, but on the other, it fuels inflation and increases the national debt if it happens to be deficit spending. Therefore, it is important for Saudi Arabia to be less dependent on government spending by diversifying its income resources, creating jobs in the private sector, and creating a stable and attractive business environment for domestic and foreign investments.", "year": 2024, "publicationDate": "2024-01-30", "publicationTypes": ["JournalArticle"], "venue": "International Journal for Scientific Research", "journal": {"name": "International Journal for Scientific Research"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://vsrp.co.uk/wp-content/uploads/10-IJSR-Vol.-3-No.-1-Jan-2024-Paper9-Dr.-Basel2.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2373915494", "name": "M. Zaini"}, {"authorId": "2282688494", "name": "Basel Balila"}], "url": "https://www.semanticscholar.org/paper/21aa163104216e2636eb930c1cea3a6c504ca84b", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "0b2e8c9a211217c2d57b838ad18854e62bc9be30", "title": "The Impact of monetary policy on inflation and production: a comparative study on Sri Lanka, India, and the USA", "abstract": "Monetary policy is a critical tool used by the Central banks to stabilize inflation and foster economic growth. Over the past few years, the Sri Lankan economy faced significant economic challenges, such as economic downturn, and rising inflation. This led the Central Bank of Sri Lanka to execute various monetary policy changes to stabilize the economy. This study examines the effects of monetary policy transmission mechanisms (MTM) on production and inflation in the USA, India, and Sri Lanka, using monthly data from 1980 to 2023, to provide a comparative understanding of how monetary policy adjustments influence each of these economies. The analysis employs the Vector Error Correction Model (VECM) to understand the short-term and long-term effects of monetary policy adjustments on Gross Domestic Production (GDP) and the Consumer Price Index (CPI). The results of this study indicate major differences in the magnitude and timing of the policy implementation and its effects across the three economies: where the USA economy indicates quicker adjustments to monetary policy changes, which reflects their advanced financial infrastructure. In contrast, India and Sri Lanka demonstrate delayed responses, suggesting inefficiencies in their policy transmission mechanisms. In addition to this, the results also indicated that in the USA, interest rates and money supply have predictive power over both CPI and GDP. This implies that policymakers can use these channels to manage inflation and economic growth. In India, none of the independent variables showed a correlation between CPI and GDP, while in Sri Lanka, domestic credit to the private sector and money supply significantly impacts GDP and CPI. These results imply that it is vital to have tailored monetary policies for each economy considering their unique structural and temporal characteristics. For the USA, the results affirm the effectiveness of its current policy framework, while India and Sri Lanka may require enhanced policy strategies to improve transmission efficiency.", "year": 2024, "publicationDate": null, "publicationTypes": ["Conference"], "venue": "7th International Conference on Business Research (ICBR 2024)", "journal": {"name": "7th International Conference on Business Research (ICBR 2024)"}, "citationCount": 0, "referenceCount": 18, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2269111968", "name": "K. K. Karunarathna"}, {"authorId": "2341555557", "name": "T. de Silva"}, {"authorId": "2341554794", "name": "S. Perera"}], "url": "https://www.semanticscholar.org/paper/0b2e8c9a211217c2d57b838ad18854e62bc9be30", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "cb8b91be70116576e274e1378f7b90a7e950b3e0", "title": "THE IMPACT OF EXCHANGE RATE VOLATILITY ON ACHIEVING THE INFLATION TARGET OF MONETARY POLICY", "abstract": "Introduction. With the transition to a new stage of global economic development, the period of low inflation is over. A new global perspective is emerging that aims to rethink the concerns of monetary authorities regarding macroeconomic and financial objectives. As a result, the new macroeconomic framework emphasizes, on the one hand, the importance of clear and appropriate regulation in combating global threats, and, on the other hand, the close link between monetary and financial stability. In this regard, the role of the central bank needs to be reconsidered in the light of its primary objective of ensuring price stability in conjunction with the goal of financial stability. Problem Statement. The use of pure and hybrid inflation targeting (hereinafter - IT) of monetary policy regimes generates academic discussions about the feasibility of including the exchange rate in the inflation target function to smooth exchange rate volatility in order to ensure price stability and economic growth in developed and emerging markets. The purpose is to examine the exchange rate volatility and its impact on achieving the inflation target under different IT regimes. Methods. The method of regression analysis to identify and quantify the relationship between exchange rate volatility and the effect of its subsequent transmission to inflation was used. Applying cluster analysis, a classification of inflation- targeting countries was carried out according to the applied exchange rate regime, which includes the analysis of two variables: the volatility of the national currency rate and the volatility of Central Bank interventions in the foreign exchange market. Results. The study of exchange rate volatility within the framework of stochastic monetary policy models finds theoretical evidence of the effectiveness of exchange rate management for inflation-targeting countries. Free floating of the exchange rate is characterized by minor interventions on the foreign exchange market combined with unlimited exchange rate fluctuations. A controlled exchange rate regime is the case when the exchange rate remains stable and interventions are volatile. In practice, exchange rate control is justified especially for emerging market countries, as their economies are usually characterized by less developed financial markets, which makes it difficult to hedge currency risks in a free-floating exchange rate environment and poses a threat to financial stability. High inflation in previous periods in emerging market economies complicates the task of achieving price stability. The width of the band takes into account the fact that by setting a wide interval for the target, the central bank makes it easier for itself to formally achieve the target. Significant fluctuations in the exchange rate can lead to fluctuations in the general price level due to the pass-through effect, making it more difficult to achieve the inflation target. According to the analysis, the coefficient on the IT variable is statistically significantly different from zero and positive. Thus, it can be assumed that the use of a hybrid IT monetary policy regime is associated with a higher probability of achieving the inflation target, even when controlling other factors. The marginal effect of switching to hybrid IT is approximately 0.27. Conclusions. Achieving the inflation target through the use of the IT regime is an important condition for macroeconomic stability for the inflation-targeting countries. Small impulses of inflation can turn into a significant permanent growth of inflation when the exchange rate is free to float. The effect of the exchange rate pass-through to prices has been reduced in countries that have switched to the hybrid IT. Since the effect of exchange rate pass-through in emerging markets is generally higher than in developed countries, the benefits of IT-based exchange rate management should be more significant for these economies. Prior to the full-scale war, the NBU used foreign exchange interventions as an auxiliary IT tool to smooth out exchange rate volatility. In times of war, there are certain regularities in the conduct of monetary policy. According to statistics, during the first military shock, the negative balance of foreign exchange interventions began to grow sharply. Given this course of events, the NBU was forced to abandon floating exchange rate IT and move to fixing the exchange rate. The introduction of a fixed exchange rate in such circumstances is a nominal anchor for expectations and an anti-inflationary tool. In such circumstances, the NBU's main operation is foreign exchange interventions to ensure the exchange rate stability. The gradual easing of currency restrictions and the transition to greater exchange rate flexibility preconditions for a gradual return to IT.", "year": 2024, "publicationDate": "2024-05-16", "publicationTypes": ["JournalArticle"], "venue": "Fìnansi Ukraïni", "journal": {"name": "Fìnansi Ukraïni"}, "citationCount": 0, "referenceCount": 16, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "123935817", "name": "O. Lyubich"}, {"authorId": "1506694091", "name": "D. Khokhych"}], "url": "https://www.semanticscholar.org/paper/cb8b91be70116576e274e1378f7b90a7e950b3e0", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "934a3a4b29d711660cca03bb12880938c09669ed", "title": "Inflation-targeting central bank responses to exchange rate shocks: evidence from Latin America", "abstract": "ABSTRACT This paper examines the impact of real exchange rate shocks on policy interest rates in the five major inflation-targeting economies in LATAM. Using a SVAR model with identification based on sign and short-run restrictions, we find that monetary policy reacts to real exchange rate shocks across all five countries. Specifically, interest rates rise directly in response to a positive real exchange rate shock (appreciation). A subsequent reversal occurs after a few quarters, with statistical significance observed in three countries. Additionally, shocks to the policy rate are demonstrated to effectively induce a real depreciation of the exchange rate.", "year": 2024, "publicationDate": "2024-03-25", "publicationTypes": ["JournalArticle"], "venue": "Applied Economics Letters", "journal": {"name": "Applied Economics Letters", "pages": "2549 - 2553", "volume": "32"}, "citationCount": 0, "referenceCount": 10, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://hdl.handle.net/10818/62768", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "1411333950", "name": "J. J. Cao-Alvira"}, {"authorId": "2292520822", "name": "Jose E. Gomez-Gonzalez"}, {"authorId": "2293475445", "name": "Julian Vallejo-Peña"}], "url": "https://www.semanticscholar.org/paper/934a3a4b29d711660cca03bb12880938c09669ed", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "ca524c64bc4b2acb34e9eb141f1fc888e5005a34", "title": "Factors influencing central bank base rates in the context of economic policy uncertainty", "abstract": "The relevance of the research topic is determined by the current unstable state of the world economy and the increasing role of central banks, which have the ability to positively influence countries’ economic development. Central banks, when implementing monetary policy, adhere to a certain strategy and accepted methods, including using monetary policy rules. The aim of this study is to evaluate the Taylor rule linking the central bank’s benchmark interest rate, the inflation rate, and the deviation of a country’s economic development from its trajectory. Developing the Taylor rule, we add a factor to the central bank reaction equation that reflects the level of uncertainty. The econometric assessment is based on statistics for two countries, the USA and the Russian Federation, whose central banks currently adhere to different monetary policy regimes introduced at different times. Despite differences between the countries’ economies and central banks’ monetary policies, uncertainty-related indices have shown their significance.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Vestnik Tomskogo gosudarstvennogo universiteta Ekonomika", "journal": {"name": "Vestnik Tomskogo gosudarstvennogo universiteta. Ekonomika"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://vital.lib.tsu.ru/vital/access/services/Download/koha:001134404/SOURCE1", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2294066589", "name": "S. Bekareva"}, {"authorId": "2294072067", "name": "E. Isupova"}, {"authorId": "2372581350", "name": "Anna S. Fedoseeva"}], "url": "https://www.semanticscholar.org/paper/ca524c64bc4b2acb34e9eb141f1fc888e5005a34", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "634dac6ab9317db4da9e60eb3f4151add70dfc32", "title": "The Impact of Monetary Policy Institutional Decisions on Convergence in Central and Eastern European Countries", "abstract": "Our study looks at the role of monetary policy related institutional decisions in the nominal and real convergence of the 11 former socialist Central and Eastern European EU Member States over the three decades following their regime change. We use our empirical model to estimate the impact of four key drivers of the monetary policy framework (exchange rate regime, central bank independence, inflation targeting, euro adoption) on inflation and real economic growth. Our main finding is that the convergence rate over the past decades has had little to do with the choice of exchange rate regime or the potential adoption of the euro or inflation targeting and much more with the establishment of central bank independence. The latter has reduced inflation by roughly 5 percentage points, while boosting real GDP growth by about 2 percentage points. This suggests that central bank independence significantly enhances the credibility and predictability of monetary policy and largely determines the success of each monetary regime.", "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "Financial and economic review", "journal": {"name": "Financial and Economic Review"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.33893/fer.23.4.120", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2252056654", "name": "György Szapáry"}, {"authorId": "1391147904", "name": "B. Vonnák"}], "url": "https://www.semanticscholar.org/paper/634dac6ab9317db4da9e60eb3f4151add70dfc32", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "a73e0b11f5d56fccc6665c42bb9e99e58f1c6e11", "title": "Monetary Policy and Inflation Expectations in Brazil: From 2005 to 2022", "abstract": "The Focus Report prepared by the Central Bank of Brazil summarizes the statistics calculated from market expectations, such as inflation expectations for the next four years that are weekly collected. The report shows the evolution of these data using graphs and weekly projections for price indices, economic activity, and exchange rates. However, the expectations of households and firms regarding the future of inflation, which are determinants for current inflation, go beyond problems of theoretical and empirical foundation. Thus, the research question addressed in this study is as follows: Do expectations of inflation measured by the Focus Market Report explain inflation measured by the CPI in Brazil? To answer this question, we compare expected and actual inflation data and analyze the correlations between them. This research is important because part of the argument for increasing the basic interest rate in the Brazilian economy is based on data from the Focus Report, which may contain forecasting errors, thereby resulting in monetary policy mistakes. The research methodology consists of contrasting data on monthly expectations with actual inflation rates and assessing the correlations between them.", "year": 2024, "publicationDate": "2024-11-08", "publicationTypes": ["JournalArticle"], "venue": "Journal of Business and Economic Studies", "journal": {"name": "Journal of Business and Economic Studies"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://jbes.scholasticahq.com/article/125536.pdf", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2298552342", "name": "Douglas Alencar"}, {"authorId": "2060283263", "name": "W. Pereira"}, {"authorId": "2329535451", "name": "Andressa Lima"}, {"authorId": "2326873614", "name": "L. Caldas"}], "url": "https://www.semanticscholar.org/paper/a73e0b11f5d56fccc6665c42bb9e99e58f1c6e11", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "b30bd0aaa3e0f816e197c94570096a079736058f", "title": "Features of the monetary policy of central banks to combat high inflation", "abstract": "The article describes the measures taken by the central banks of the world's largest economies to combat high inflation. The authors give a definition of what exactly is considered high inflation, analyze the timeliness and effectiveness of taking anti-inflationary measures, and also answer the question of the need for the monetary authorities to react to inflation, which does not have an obvious monetary nature. \nIn the article the particular attention is paid to the difference between the anti-inflationary policy of central banks in developed and emerging markets, as well as to the issues of coordination between the actions of the central bank and the government in the field of anti-inflationary policy. The authors point out the importance of increasing the efficiency of the transmission mechanism through the development of various segments of the financial market, including the derivatives market. \nAs a result of the study, a hypothesis is put forward that there is a direct relationship between the development of the financial market, especially the capital market, and the costs of fighting inflation. Countries with less developed capital markets and smaller gold and foreign exchange reserves are forced to use the key rate of central banks to fight inflation, paying with their economic growth potential for the opportunity to have low inflation. \nThe article also makes a fundamental conclusion that the risk of inflation has acquired global features, however has not yet affected all countries, bypassing those markets that traditionally struggled with the deflation factor, and their central banks had negative rates. As well, the article pays attention to the dependence of the foreign exchange rate on the difference between the levels of interest rates, and makes assumptions about the possibility of manipulating the foreign exchange rate through delaying anti-inflationary measures in order to stimulate exports.", "year": 2022, "publicationDate": "2022-06-27", "publicationTypes": [], "venue": "VUZF Review", "journal": {"name": "VUZF Review"}, "citationCount": 3, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://papersvuzf.net/index.php/VUZF/article/download/267/253", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2140984329", "name": "Vitaliy Shapran"}, {"authorId": "90858035", "name": "Igor Britchenko"}], "url": "https://www.semanticscholar.org/paper/b30bd0aaa3e0f816e197c94570096a079736058f", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "710830896030222b9016273bef8bfb977429485c", "title": "Effectiveness of Monetary and Fiscal Policies Fiscal Policy Effectiveness on Inflation and Unemployment Reduction in South Kalimantan", "abstract": "This research aims to analyze the effectiveness of monetary and fiscal policies in combating inflation and unemployment in South Kalimantan and Indonesia. Reliable primary data sources such as journals, the Central Bureau of Statistics, and the official website of Bank Indonesia were utilized in this qualitative analysis. Indonesia, as a developing country, faces economic stability challenges, and monetary and fiscal policies are crucial instruments used by the government and central bank to regulate inflation and the overall economy. South Kalimantan, despite its abundant natural resources, still encounters economic disparities between urban and rural areas and sustainable resource management issues. To address these challenges, the government implements monetary and fiscal policies to facilitate economic control. The central bank aims to balance the money supply and commodity availability to achieve controlled inflation, full employment, and smooth commodity distribution. Fiscal policy plays a vital role in regulating macroeconomic balance and influencing short-term economic demand while also impacting long-term economic capacity. The research findings indicate the effectiveness of these policies, demonstrated by the controlled inflation rate in 2022 due to their implementation by the government", "year": 2024, "publicationDate": "2024-08-07", "publicationTypes": ["JournalArticle"], "venue": "Tawazuna", "journal": {"name": "Tawazuna"}, "citationCount": 0, "referenceCount": 6, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://journal.umbjm.ac.id/index.php/tawazuna/article/download/810/PDF", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2320551680", "name": "Ananda Aulia Futra"}, {"authorId": "2320554439", "name": "Sepreika Mutiyara"}, {"authorId": "2320552472", "name": "Dewi Maharani"}, {"authorId": "2279050003", "name": "Universitas Muhammadiyah Banjarmasin"}, {"authorId": "2329383546", "name": "S3 Prodi"}, {"authorId": "2088359421", "name": "Perbankan Syari’ah"}], "url": "https://www.semanticscholar.org/paper/710830896030222b9016273bef8bfb977429485c", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "59b2e8549deb9c43f8d0f64a3b1ad0baf1733861", "title": "Post-COVID inflation and the monetary policy dilemma: an agent-based scenario analysis", "abstract": "The economic shocks that followed the COVID-19 pandemic have brought to light the difficulty, both for academics and policy makers, of describing and predicting the dynamics of inflation. This paper offers an alternative modelling approach. We study the 2020–2023 period within the well-studied Mark-0 Agent-Based Model, in which economic agents act and react according to plausible behavioural rules. We include a mechanism through which trust of economic agents in the Central Bank can de-anchor. We investigate the influence of regulatory policies on inflationary dynamics resulting from three exogenous shocks, calibrated on those that followed the COVID-19 pandemic: a production/consumption shock due to COVID-related lockdowns, a supply chain shock, and an energy price shock exacerbated by the Russian invasion of Ukraine. By exploring the impact of these shocks under different assumptions about monetary policy efficacy and transmission channels, we review various explanations for the resurgence of inflation in the USA, including demand-pull, cost-push, and profit-driven factors. Our main results are fourfold: (i) without appropriate fiscal policy, the shocked economy can take years to recover, or even tip over into a deep recession; (ii) the success of monetary policy in curbing inflation is primarily due to expectation anchoring, rather than to the direct economic impact of interest rate hikes; (iii) however, perhaps paradoxically, strong inflation anchoring is detrimental to consumption and unemployment, leading to a narrow window of “optimal” policy responses due to the trade-off between inflation and unemployment; (iv) the two most sensitive model parameters are those describing wage and price indexation. The results of our study have implications for Central Bank decision-making, and offer an easy-to-use tool that may help anticipate the consequences of different monetary and fiscal policies.", "year": 2023, "publicationDate": "2023-06-02", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Economic Interaction and Coordination", "journal": {"name": "Journal of Economic Interaction and Coordination", "pages": "141 - 195", "volume": "20"}, "citationCount": 16, "referenceCount": 55, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s11403-024-00413-3.pdf", "fieldsOfStudy": ["Economics", "Physics"], "s2FieldsOfStudy": [{"category": "Economics", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "2140578075", "name": "M. Knicker"}, {"authorId": "2127474995", "name": "Karl Naumann-Woleske"}, {"authorId": "2524821", "name": "J. Bouchaud"}, {"authorId": "2434160", "name": "F. Zamponi"}], "url": "https://www.semanticscholar.org/paper/59b2e8549deb9c43f8d0f64a3b1ad0baf1733861", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "3301ee1846519a42e461670bc844cd2aeeee3384", "title": "‘Independence’ of Central Banks and the Political Economy of Monetary Policy", "abstract": "ABSTRACT The notion of an ‘independent’ central bank has dominated monetary policy debates for the past three decades. The arguments for the political independence of central banks are closely related to the adoption of ‘inflation targeting’. The arguments for an independent central bank are based on the ‘credibility’ of the ‘conservative’ central bank in comparison to government decision making. The independence of a central bank has been a matter of independence from government but not independence from the grip of the ‘new consensus in macroeconomics’ nor from the interests of the banking and financial sector. That independence has also supported a lack of co-ordination between monetary and fiscal policies, diminishing the effectiveness of macroeconomic policies. In addition, there remain doubts about the effectiveness of ‘inflation targeting’ on the achievement of low inflation. The policy mandates of central banks have begun to shift towards financial stability and paying attention to issues of inequality and the climate emergency.", "year": 2023, "publicationDate": "2023-04-27", "publicationTypes": ["JournalArticle"], "venue": "Review of Political Economy", "journal": {"name": "Review of Political Economy", "pages": "565 - 580", "volume": "36"}, "citationCount": 20, "referenceCount": 57, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.tandfonline.com/doi/pdf/10.1080/09538259.2023.2189006?needAccess=true&role=button", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}, {"category": "Political Science", "source": "s2-fos-model"}], "authors": [{"authorId": "123179577", "name": "J. Qanas"}, {"authorId": "152513200", "name": "M. Sawyer"}], "url": "https://www.semanticscholar.org/paper/3301ee1846519a42e461670bc844cd2aeeee3384", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "ef0f95b4d10f1aa329a936a36bd3430befd3c70c", "title": "The effectiveness of ultra-loose monetary policy in a high inflation economy: a time-varying causality analysis for Turkey", "abstract": null, "year": 2023, "publicationDate": "2023-07-18", "publicationTypes": ["JournalArticle"], "venue": "Economic Change and Restructuring", "journal": {"name": "Economic Change and Restructuring", "pages": "2855-2887", "volume": "56"}, "citationCount": 12, "referenceCount": 87, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Economics", "source": "s2-fos-model"}], "authors": [{"authorId": "143676805", "name": "M. Ulug"}, {"authorId": "46691917", "name": "Sayım Işık"}, {"authorId": "2094390269", "name": "Mehmet Mert"}], "url": "https://www.semanticscholar.org/paper/ef0f95b4d10f1aa329a936a36bd3430befd3c70c", "_run_id": "9B4Te5uyJV56WrLWp", "_dataset_id": "KeRjuzyTN0QDsAsXj"}
{"paperId": "dc1a523979a02a1c714de4ebce325015e6d0ff67", "title": "2D Layered Nanomaterials as Fillers in Polymer Composite Electrolytes for Lithium Batteries", "abstract": "Polymer composite electrolytes (PCEs), i.e., materials combining the disciplines of polymer chemistry, inorganic chemistry, and electrochemistry, have received tremendous attention within academia and industry for lithium‐based battery applications. While PCEs often comprise 3D micro‐ or nanoparticles, this review thoroughly summarizes the prospects of 2D layered inorganic, organic, and hybrid nanomaterials as active (ion conductive) or passive (nonion conductive) fillers in PCEs. The synthetic inorganic nanofillers covered here include graphene oxide, boron nitride, transition metal chalcogenides, phosphorene, and MXenes. Furthermore, the use of naturally occurring 2D layered clay minerals, such as layered double hydroxides and silicates, in PCEs is also thoroughly detailed considering their impact on battery cell performance. Despite the dominance of 2D layered inorganic materials, their organic and hybrid counterparts, such as 2D covalent organic frameworks and 2D metal–organic frameworks are also identified as tuneable nanofillers for use in PCE. Hence, this review gives an overview of the plethora of options available for the selective development of both the 2D layered nanofillers and resulting PCEs, which can revolutionize the field of polymer‐based solid‐state electrolytes and their implementation in lithium and post‐lithium batteries.", "year": 2023, "publicationDate": "2023-03-11", "publicationTypes": ["Review"], "venue": "Advanced Energy Materials", "journal": {"name": "Advanced Energy Materials", "volume": "13"}, "citationCount": 102, "referenceCount": 293, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aenm.202203326", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "144099394", "name": "Vidyanand Vijayakumar"}, {"authorId": "66665314", "name": "Meena Ghosh"}, {"authorId": "2049303190", "name": "K. Asokan"}, {"authorId": "2134175939", "name": "Santhosh Babu Sukumaran"}, {"authorId": "3874402", "name": "Sreekumar Kurungot"}, {"authorId": "5349147", "name": "Jonas Mindemark"}, {"authorId": "9888867", "name": "D. Brandell"}, {"authorId": "143716425", "name": "M. Winter"}, {"authorId": "91446002", "name": "J. Nair"}], "url": "https://www.semanticscholar.org/paper/dc1a523979a02a1c714de4ebce325015e6d0ff67", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "a8ce5b331bd874bf7b8d4a4b48bd0bcad6ac8387", "title": "Antimicrobial Properties of 2D MnO2 and MoS2 Nanomaterials Vertically Aligned on Graphene Materials and Ti3C2 MXene.", "abstract": "Two-dimensional (2D) nanomaterials have attracted considerable attention in biomedical and environmental applications due to their antimicrobial activity. In the interest of investigating the primary antimicrobial mode-of-action of 2D nanomaterials, we studied the antimicrobial properties of MnO2 and MoS2, toward Gram-positive and Gram-negative bacteria. Bacillus subtilis and Escherichia coli bacteria were treated individually with 100 μg/mL of randomly oriented and vertically aligned nanomaterials for ∼3 h in the dark. The vertically aligned 2D MnO2 and MoS2 were grown on 2D sheets of graphene oxide, reduced graphene oxide, and Ti3C2 MXene. Measurements to determine the viability of bacteria in the presence of the 2D nanomaterials performed by using two complementary techniques, flow cytometry, and fluorescence imaging showed that, while MnO2 and MoS2 nanosheets show different antibacterial activities, in both cases, Gram-positive bacteria show a higher loss in membrane integrity. Scanning electron microscopy images suggest that the 2D nanomaterials, which have a detrimental effect on bacteria viability, compromise the cell wall, leading to significant morphological changes. We propose that the peptidoglycan mesh (PM) in the bacterial wall is likely the primary target of the 2D nanomaterials. Vertically aligned 2D MnO2 nanosheets showed the highest antimicrobial activity, suggesting that the edges of the nanosheets were likely compromising the cell walls upon contact.", "year": 2018, "publicationDate": "2018-05-21", "publicationTypes": ["JournalArticle"], "venue": "Langmuir", "journal": {"name": "Langmuir : the ACS journal of surfaces and colloids", "pages": "\n          7192-7200\n        ", "volume": "34 24"}, "citationCount": 123, "referenceCount": 0, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://figshare.com/articles/journal_contribution/Antimicrobial_Properties_of_2D_MnO_sub_2_sub_and_MoS_sub_2_sub_Nanomaterials_Vertically_Aligned_on_Graphene_Materials_and_Ti_sub_3_sub_C_sub_2_sub_MXene/6453014/1/files/11869469.pdf", "fieldsOfStudy": ["Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "49651314", "name": "F. Alimohammadi"}, {"authorId": "81751224", "name": "Mohammad Sharifian Gh."}, {"authorId": "48993677", "name": "N. Attanayake"}, {"authorId": "9658430", "name": "Akila C. Thenuwara"}, {"authorId": "144061594", "name": "Y. Gogotsi"}, {"authorId": "8399120", "name": "B. Anasori"}, {"authorId": "4675021", "name": "D. Strongin"}], "url": "https://www.semanticscholar.org/paper/a8ce5b331bd874bf7b8d4a4b48bd0bcad6ac8387", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "4c80e277de1bd34316011e4b81a3805f83305d13", "title": "Graphene based 2D-materials for supercapacitors", "abstract": null, "year": 2015, "publicationDate": "2015-07-15", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "2D Materials", "volume": "2"}, "citationCount": 103, "referenceCount": 307, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Materials Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "15570880", "name": "Thangavelu Palaniselvam"}, {"authorId": "6214826", "name": "Jong‐Beom Baek"}], "url": "https://www.semanticscholar.org/paper/4c80e277de1bd34316011e4b81a3805f83305d13", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "90cbc9f457fddafd2f85828b12e56430bb2a1c14", "title": "Large‐Scale Syntheses of 2D Materials: Flash Joule Heating and Other Methods", "abstract": "In the past 17 years, the larger‐scale production of graphene and graphene family materials has proven difficult and costly, thus slowing wider‐scale commercial applications. The quality of the graphene that is prepared on larger scales has often been poor, demonstrating a need for improved quality controls. Here, current industrial graphene synthetic and analytical methods, as well as recent academic advancements in larger‐scale or sustainable synthesis of graphene, defined here as weights more than 200 mg or films larger than 200 cm2, are compiled and reviewed. There is a specific emphasis on recent research in the use of flash Joule heating as a rapid, efficient, and scalable method to produce graphene and other 2D nanomaterials. Reactor design, synthetic strategies, safety considerations, feedstock selection, Raman spectroscopy, and future outlooks for flash Joule heating syntheses are presented. To conclude, the remaining challenges and opportunities in the larger‐scale synthesis of graphene and a perspective on the broader use of flash Joule heating for larger‐scale 2D materials synthesis are discussed.", "year": 2021, "publicationDate": "2021-10-25", "publicationTypes": ["Review", "JournalArticle"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "34"}, "citationCount": 164, "referenceCount": 5, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://rss.onlinelibrary.wiley.com/doi/am-pdf/10.1002/adma.202106970", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "96292826", "name": "K. Wyss"}, {"authorId": "14538459", "name": "D. Luong"}, {"authorId": "2175219", "name": "J. Tour"}], "url": "https://www.semanticscholar.org/paper/90cbc9f457fddafd2f85828b12e56430bb2a1c14", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "b171aa4bee89780678107ba9869d0b0d1ac0f2b5", "title": "Exfoliation of 2D Materials for Energy and Environmental Applications.", "abstract": "The fascinating properties of single-layer graphene isolated by mechanical exfoliation have inspired extensive research efforts toward two-dimensional (2D) materials. Layered compounds serve as precursors for atomically thin 2D materials (briefly, 2D nanomaterials) owing to their strong intraplane chemical bonding but weak interplane van der Waals interactions. There are newly emerging 2D materials beyond graphene, and it is becoming increasingly important to develop cost-effective, scalable methods for producing 2D nanomaterials with controlled microstructures and properties. The variety of developed synthetic techniques can be categorized into two classes: bottom-up and top-down approaches. Of top-down approaches, the exfoliation of bulk 2D materials into single or few layers is the most common. This review highlights chemical and physical exfoliation methods that allow for the production of 2D nanomaterials in large quantities. In addition, remarkable examples of utilizing exfoliated 2D nanomaterials in energy and environmental applications are introduced.", "year": 2020, "publicationDate": "2020-03-11", "publicationTypes": ["JournalArticle", "Review"], "venue": "Chemistry", "journal": {"name": "Chemistry"}, "citationCount": 119, "referenceCount": 282, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "8660584", "name": "Thanh-Hai Le"}, {"authorId": "95986398", "name": "Yuree Oh"}, {"authorId": "49717791", "name": "Hyungwoo Kim"}, {"authorId": "3849351", "name": "Hyeonseok Yoon"}], "url": "https://www.semanticscholar.org/paper/b171aa4bee89780678107ba9869d0b0d1ac0f2b5", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "e8cc2d97554a37d9121515655fddce858f4e3518", "title": "Powerful combination of 2D g-C3N4 and 2D nanomaterials for photocatalysis: Recent advances", "abstract": "Abstract As a fascinating metal-free conjugated polymer semiconductor, 2D graphitic carbon nitride (g-C3N4) has been widely used as a visible-light-responsive photocatalyst. Generally, g-C3N4 exhibits some appealing properties, such as exceptional thermal and chemical stability, appropriate band structure, as well as low cost. However, the pristine g-C3N4 is limited by the fast recombination of the photoinduced electron-hole pairs, limited surface area, and insufficient sunlight absorption. Very recently, the construction of 2D/2D heterojunctions has attracted widespread attention owing to their distinct advantages, including the intimate interface, high surface area, suitable band potential and so forth. Therefore, this review summarized the latest progress in the coupling g-C3N4 with other 2D nanomaterial systems, including 2D graphene-like materials, 2D transition metal dichalcogenides, 2D metal oxides, 2D bismuth-based semiconductors and 2D phosphorous. Furthermore, the photocatalytic mechanism of g-C3N4 based 2D/2D heterojunctions was systematically studied and their corresponding charge-transfer pathways on the interface surface were elaborated. In addition, the photocatalytic applications of the g-C3N4 based 2D/2D composites in the realm of hydrogen generation, carbon dioxide reduction, pollutant degradation, and photocatalytic disinfection were also reviewed. Finally, the current challenges faced by the formation of g-C3N4 based 2D/2D composite and the opportunities for further development are also proposed.", "year": 2020, "publicationDate": "2020-06-15", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Chemical Engineering Journal", "pages": "124475", "volume": "390"}, "citationCount": 261, "referenceCount": 223, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2149173169", "name": "Xin Zhang"}, {"authorId": "1689982", "name": "Xingzhong Yuan"}, {"authorId": "14215696", "name": "Longbo Jiang"}, {"authorId": "2108931063", "name": "Jin Zhang"}, {"authorId": "46492986", "name": "Hanbo Yu"}, {"authorId": "97699895", "name": "Hou Wang"}, {"authorId": "144252351", "name": "G. Zeng"}], "url": "https://www.semanticscholar.org/paper/e8cc2d97554a37d9121515655fddce858f4e3518", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "d77470160250b41eaa290031d1981ca0f9c60280", "title": "Gas sensing in 2D materials", "abstract": null, "year": 2017, "publicationDate": "2017-05-16", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Applied physics reviews", "pages": "021304", "volume": "4"}, "citationCount": 729, "referenceCount": 233, "influentialCitationCount": 5, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "3843696", "name": "Shengxue Yang"}, {"authorId": "5764638", "name": "Chengbao Jiang"}, {"authorId": "11700038", "name": "Suhuai Wei"}], "url": "https://www.semanticscholar.org/paper/d77470160250b41eaa290031d1981ca0f9c60280", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "33397f33f2f6b6624aa0dbcf804bf5d92f27460e", "title": "Recent advances of monoelemental 2D materials for photocatalytic applications.", "abstract": "As a sustainable environmental governance strategy and energy conversion method, photocatalysis has considered to have great potential in this field due to its excellent optical properties and has become one of the most attractive technologies today. Among 2D materials, the emerging two-dimensional (2D) monoelemental materials mainly distributed in the -IIIA, -IVA, -VA and -VIA groups and show excellent performance in solar energy conversion due to their graphene-like 2D atomic structure and unique properties, thereby drawing increasing attention. This review briefly summarizes the preparation processes and fundamental properties of 2D single-element nanomaterials, as well as various modification strategies and adjustment mechanisms to enhance their photocatalytic properties. In particular, this article comprehensively discusses the related practical applications of 2D single-element materials in the field of photocatalysis, including photocatalytic degradation for contaminants removal, photocatalytic pathogen inactivation, photocatalytic fouling control and photocatalytic energy conversion. This review will provide some new opportunities for the rational design of other excellent photocatalysts based on 2D monoelemental materials, as well as present tremendous novel ideas for 2D monoelemental materials in other environmental conservation and energy-related applications, such as supercapacitors, electrocatalysis, solar cells, and so on.", "year": 2020, "publicationDate": "2020-10-23", "publicationTypes": ["Review", "JournalArticle"], "venue": "Journal of Hazardous Materials", "journal": {"name": "Journal of hazardous materials", "pages": "\n          124179\n        "}, "citationCount": 103, "referenceCount": 209, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2067784357", "name": "Rong Hu"}, {"authorId": "1657588848", "name": "Gengcheng Liao"}, {"authorId": "14042404", "name": "Zongyu Huang"}, {"authorId": "72601688", "name": "H. Qiao"}, {"authorId": "2145488118", "name": "Huating Liu"}, {"authorId": "1381874688", "name": "Yiqing Shu"}, {"authorId": "46270169", "name": "Bing Wang"}, {"authorId": "145942161", "name": "X. Qi"}], "url": "https://www.semanticscholar.org/paper/33397f33f2f6b6624aa0dbcf804bf5d92f27460e", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "ea1f54eca97c40101af5e0e9f81043fe9b3a3fcc", "title": "Recent Advances in 2D Inorganic Nanomaterials for SERS Sensing", "abstract": "Surface‐enhanced Raman spectroscopy is a powerful and sensitive analytical tool that has found application in chemical and biomolecule analysis and environmental monitoring. Since its discovery in the early 1970s, a variety of materials ranging from noble metals to nanostructured materials have been employed as surface enhanced Raman scattering (SERS) substrates. In recent years, 2D inorganic materials have found wide use in the development of SERS‐based chemical sensors owing to their unique thickness dependent physico‐chemical properties with enhanced chemical‐based charge‐transfer processes. Here, recent advances in the application of various 2D inorganic nanomaterials, including graphene, boron nitride, semiconducting metal oxides, and transition metal chalcogenides, in chemical detection via SERS are presented. The background of the SERS concept, including its basic theory and sensing mechanism, along with the salient features of different nanomaterials used as substrates in SERS, extending from monometallic nanoparticles to nanometal oxides, is comprehensively discussed. The importance of 2D inorganic nanomaterials in SERS enhancement, along with their application toward chemical detection, is explained in detail with suitable examples and illustrations. In conclusion, some guidelines are presented for the development of this promising field in the future.", "year": 2019, "publicationDate": "2019-02-18", "publicationTypes": ["Review", "JournalArticle"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "31"}, "citationCount": 256, "referenceCount": 249, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://discovery.ucl.ac.uk/10069800/1/adma.201803432_R2.pdf", "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "13694471", "name": "Padmanathan Karthick Kannan"}, {"authorId": "1730769", "name": "Prabakaran Shankar"}, {"authorId": "144045021", "name": "C. Blackman"}, {"authorId": "7984045", "name": "C. Chung"}], "url": "https://www.semanticscholar.org/paper/ea1f54eca97c40101af5e0e9f81043fe9b3a3fcc", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "ec88c50340442e014978bccddef91170d60941d3", "title": "Defect chemistry in 2D materials for electrocatalysis", "abstract": "Abstract Two-dimensional (2D) nanomaterials, including metal-free (graphene, carbon nitride, and black phosphorus et al.) and transition metal-based materials (dichalcogenides, oxides, hydroxides, phosphides, and MXenes et al.), have emerged as promising candidates for electrocatalysis due to their unique physical, chemical, and electronic properties. Specifically, 2D materials with ultra-thin thickness usually possess more vacancy-type defects and exposed edges than bulk materials, resulting in different electronic characteristics relative to those of bulk materials and leading to changes in the reactant absorption energy on catalysts. Introducing heteroatom dopants can further alter the charge distribution in 2D materials, thereby facilitating the formation of new defects and catalytic active-sites to improve the electrocatalytic performance. This review highlights recent defect chemistry advances and developments in 2D materials for electrocatalysis. We discuss various defects in 2D materials, such as edge defects, topological defects and vacancy defects so on, and the effects of defects on electrocatalytic performance. Defect engineering and rational design strategies for controlling defects on 2D materials will also be systematically discussed. Finally, various advanced characterization technologies to reveal different types of defects will be discussed.", "year": 2019, "publicationDate": "2019-06-01", "publicationTypes": ["Review"], "venue": "Materials Today Energy", "journal": {"name": "Materials Today Energy"}, "citationCount": 149, "referenceCount": 240, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2087036677", "name": "T. Sun"}, {"authorId": "2019132363", "name": "Guoqiang Zhang"}, {"authorId": "2116459645", "name": "Dong Xu"}, {"authorId": "1750934322", "name": "X. Lian"}, {"authorId": "11307418", "name": "Hexing Li"}, {"authorId": "40094004", "name": "Wei Chen"}, {"authorId": "100853009", "name": "C. Su"}], "url": "https://www.semanticscholar.org/paper/ec88c50340442e014978bccddef91170d60941d3", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "6cc4997658feb1364f063004573cffc8430e5f7a", "title": "Flame retardant nanocomposites based on 2D layered nanomaterials: a review", "abstract": null, "year": 2019, "publicationDate": "2019-10-01", "publicationTypes": ["Review"], "venue": "Journal of Materials Science", "journal": {"name": "Journal of Materials Science", "pages": "13070 - 13105", "volume": "54"}, "citationCount": 111, "referenceCount": 288, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "39174972", "name": "Xiaopeng Yue"}, {"authorId": "2150359121", "name": "Chaofan Li"}, {"authorId": "143724131", "name": "Y. Ni"}, {"authorId": "13849882", "name": "Yongjian Xu"}, {"authorId": "2152765663", "name": "Jian Wang"}], "url": "https://www.semanticscholar.org/paper/6cc4997658feb1364f063004573cffc8430e5f7a", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "1cf7a584f63e97c5f81e27c47c897a672330039b", "title": "Recent Developments in 2D Nanomaterials for Chemiresistive-Type Gas Sensors", "abstract": "Two-dimensional (2D) nanostructures are gaining tremendous interests due to the fascinating physical, chemical, electrical, and optical properties. Recent advances in 2D nanomaterials synthesis have contributed to optimization of various parameters such as physical dimension and chemical structure for specific applications. In particular, development of high performance gas sensors is gaining vast importance for real-time and on-site environmental monitoring by detection of hazardous chemical species. In this review, we comprehensively report recent achievements of 2D nanostructured materials for chemiresistive-type gas sensors. Firstly, the basic sensing mechanism is described based on charge transfer behavior between gas species and 2D nanomaterials. Secondly, diverse synthesis strategies and characteristic gas sensing properties of 2D nanostructures such as graphene, metal oxides, transition metal dichalcogenides (TMDs), metal organic frameworks (MOFs), phosphorus, and MXenes are presented. In addition, recent trends in synthesis of 2D heterostructures by integrating two different types of 2D nanomaterials and their gas sensing properties are discussed. Finally, this review provides perspectives and future research directions for gas sensor technology using various 2D nanomaterials.Graphical Abstract", "year": 2018, "publicationDate": "2018-03-08", "publicationTypes": ["Review"], "venue": "Electronic Materials Letters", "journal": {"name": "Electronic Materials Letters", "pages": "221-260", "volume": "14"}, "citationCount": 257, "referenceCount": 234, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://dspace.mit.edu/bitstream/1721.1/131924/1/13391_2018_44_ReferencePDF.pdf", "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "6432858", "name": "Seon-Jin Choi"}, {"authorId": "145902540", "name": "Il‐Doo Kim"}], "url": "https://www.semanticscholar.org/paper/1cf7a584f63e97c5f81e27c47c897a672330039b", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "41bd57cdcbcbdeb1b80e7f46450bbdad1722d3ea", "title": "Two-Dimensional (2D) Nanomaterials towards Electrochemical Nanoarchitectonics in Energy-Related Applications", "abstract": null, "year": 2017, "publicationDate": "2017-02-24", "publicationTypes": [], "venue": null, "journal": {"name": "Bulletin of the Chemical Society of Japan", "pages": "627-648", "volume": "90"}, "citationCount": 366, "referenceCount": 304, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.journal.csj.jp/doi/pdf/10.1246/bcsj.20170043", "fieldsOfStudy": ["Chemistry"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "1399943043", "name": "A. Khan"}, {"authorId": "5945797", "name": "Srabanti Ghosh"}, {"authorId": "143620127", "name": "B. Pradhan"}, {"authorId": "16150883", "name": "A. Dalui"}, {"authorId": "8240027", "name": "L. Shrestha"}, {"authorId": "143806692", "name": "S. Acharya"}, {"authorId": "2408235", "name": "K. Ariga"}], "url": "https://www.semanticscholar.org/paper/41bd57cdcbcbdeb1b80e7f46450bbdad1722d3ea", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "9b6ee47027d7ccc1c7d696d5762fc10554382e31", "title": "Recent advances in graphene-based nanomaterials for fabricating electrochemical hydrogen peroxide sensors.", "abstract": null, "year": 2017, "publicationDate": "2017-03-15", "publicationTypes": ["Review", "JournalArticle"], "venue": "Biosensors & bioelectronics", "journal": {"name": "Biosensors & bioelectronics", "pages": "\n          249-268\n        ", "volume": "89 Pt 1"}, "citationCount": 322, "referenceCount": 182, "influentialCitationCount": 3, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "48264082", "name": "Ruizhong Zhang"}, {"authorId": null, "name": "Wei Chen"}], "url": "https://www.semanticscholar.org/paper/9b6ee47027d7ccc1c7d696d5762fc10554382e31", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "89a140a09a1500a7ccf412af6058ab17d45c83ad", "title": "Electronic structure engineering on two-dimensional (2D) electrocatalytic materials for oxygen reduction, oxygen evolution, and hydrogen evolution reactions", "abstract": "Abstract Two-dimensional (2D) materials with the conservation of 2D configuration are excellent candidates for fundamental energy conversion and storage research and potential candidate for commercial applications. In this regard, this comprehensive review highlights the recent advances in the electronic structure tuning of 2D materials such as carbon/graphene, metal chalcogenides, metal oxides/hydroxides, MXenes, toward electrocatalytic energy conversions such as oxygen reduction reaction (ORR), oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). First, this review offers a systematic summary of the classification, controllable synthesis, and formation mechanism of 2D nanomaterials. Later, the strategies for tuning the electronic structure of 2D nanomaterials, and further their impact on electrocatalytic properties are summarized, namely doping, defect engineering, temperature effect, composite and heterostructure formation. The recent development of electrocatalysts with novel nanosheets structures and compositions were discussed deeply. The understandings of the correlation between the electronic nature, activity and the shape, size, composition, and synthesis methods were summarized. Finally, some personal perspectives on future challenges of this research field will also be presented.", "year": 2020, "publicationDate": "2020-11-01", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Nano Energy", "pages": "105080", "volume": "77"}, "citationCount": 207, "referenceCount": 360, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "49745636", "name": "Sundaram Chandrasekaran"}, {"authorId": "19367539", "name": "Dingtao Ma"}, {"authorId": "49982531", "name": "Yanqi Ge"}, {"authorId": "1905572", "name": "Libo Deng"}, {"authorId": "67205128", "name": "C. Bowen"}, {"authorId": "50103007", "name": "J. Roscow"}, {"authorId": "2152819246", "name": "Yan Zhang"}, {"authorId": "1680778", "name": "Zhiqun Lin"}, {"authorId": "114125137", "name": "R. Misra"}, {"authorId": "2108981199", "name": "Jianqing Li"}, {"authorId": "51264729", "name": "Peixin Zhang"}, {"authorId": "2119077936", "name": "Han Zhang"}], "url": "https://www.semanticscholar.org/paper/89a140a09a1500a7ccf412af6058ab17d45c83ad", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f1c3f5aa663e06eb7c54ec6db4a4568f24ba6ac1", "title": "Electrochemical exfoliation of graphene-like two-dimensional nanomaterials.", "abstract": "Unlike zero-dimensional quantum dots, one-dimensional nanowires/nanorods, and three-dimensional networks or even their bulk counterparts, the charge carriers in two-dimensional (2D) materials are confined along the thickness while being allowed to move along the plane. They have distinct characteristics like strong quantum confinement, tunable thickness, and high specific surface area, which makes them a promising candidate in a wide range of applications such as electronics, topological spintronic devices, energy storage, energy conversion, sensors, biomedicine, catalysis, and so on. After the discovery of the extraordinary properties of graphene, other graphene-like 2D materials have attracted a great deal of attention. Like graphene, to realize their potential applications, high efficiency and low cost industrial scale methods should be developed to produce high-quality 2D materials. The electrochemical methods usually performed under mild conditions are convenient, controllable, and suitable for mass production. In this review, we introduce the latest and most representative investigations on the fabrication of 2D monoelemental Xenes, 2D transition-metal dichalcogenides, and other important emerging 2D materials such as organic framework (MOF) nanosheets and MXenes through electrochemical exfoliation. The electrochemical exfoliation conditions of the bulk layered materials are discussed. The numerous factors which will affect the quality of the exfoliated 2D materials, the possible exfoliating mechanism and potential applications are summarized and discussed in detail. A summary of the discussion together with perspectives and challenges for the future of this emerging field is also provided in the last section.", "year": 2018, "publicationDate": null, "publicationTypes": ["Review", "JournalArticle"], "venue": "Nanoscale", "journal": {"name": "Nanoscale", "pages": "\n          16-33\n        ", "volume": "11 1"}, "citationCount": 166, "referenceCount": 125, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "49307748", "name": "Yingchang Yang"}, {"authorId": "5604028", "name": "Hong-shuai Hou"}, {"authorId": "8728986", "name": "Guoqiang Zou"}, {"authorId": "2107645641", "name": "W. Shi"}, {"authorId": "51425501", "name": "Honglei Shuai"}, {"authorId": "119581975", "name": "Jiayang Li"}, {"authorId": "2901854", "name": "Xiaobo Ji"}], "url": "https://www.semanticscholar.org/paper/f1c3f5aa663e06eb7c54ec6db4a4568f24ba6ac1", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "39a07ff6cce54db42c7178772fe8044986522e13", "title": "Hybrids of Fullerenes and 2D Nanomaterials", "abstract": "Fullerene has a definite 0D closed‐cage molecular structure composed of merely sp2‐hybridized carbon atoms, enabling it to serve as an important building block that is useful for constructing supramolecular assemblies and micro/nanofunctional materials. Conversely, graphene has a 2D layered structure, possessing an exceptionally large specific surface area and high carrier mobility. Likewise, other emerging graphene‐analogous 2D nanomaterials, such as graphitic carbon nitride (g‐C3N4), transition‐metal dichalcogenides (TMDs), hexagonal boron nitride (h‐BN), and black phosphorus (BP), show unique electronic, physical, and chemical properties, which, however, exist only in the form of a monolayer and are typically anisotropic, limiting their applications. Upon hybridization with fullerenes, noncovalently or covalently, the physical/chemical properties of 2D nanomaterials can be tailored and, in most cases, improved, significantly extending their functionalities and applications. Here, an exhaustive review of all types of hybrids of fullerenes and 2D nanomaterials, such as graphene, g‐C3N4, TMDs, h‐BN, and BP, including their preparations, structures, properties, and applications, is presented. Finally, the prospects of fullerene‐2D nanomaterial hybrids, especially the opportunity of creating unknown functional materials by means of hybridization, are envisioned.", "year": 2018, "publicationDate": "2018-09-02", "publicationTypes": ["Review", "JournalArticle"], "venue": "Advancement of science", "journal": {"name": "Advanced Science", "volume": "6"}, "citationCount": 123, "referenceCount": 140, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/advs.201800941", "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "143756970", "name": "Muqing Chen"}, {"authorId": "35285777", "name": "Runnan Guan"}, {"authorId": "2115298463", "name": "Shangfeng Yang"}], "url": "https://www.semanticscholar.org/paper/39a07ff6cce54db42c7178772fe8044986522e13", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f525daa4f289f1d07441fbc29dabbc3827bfad7a", "title": "Recent advances in emerging 2D nanomaterials for biosensing and bioimaging applications", "abstract": "Abstract The great success of graphene throws new light on discovering more two-dimensional (2D) layered nanomaterials that stem from atomically thin 2D sheets. Compared with a single element of graphene, emerging graphene-like 2D materials composed of multiple elements that possess more versatility, greater flexibility and better functionality with a wide range of potential applications. In this review, we provide insights into the rapidly emerging 2D materials and their biosensing and bioimaging applications in recent three years, including 2D transition metal nanomaterials, graphitic nitride materials, black phosphorus, and emerging 2D organic polymers. We first briefly highlight their unique 2D morphology and physicochemical properties and then focus on their recent applications in electrochemical biosensing, optical biosensing and bioimaging. The challenges and some thoughts on future perspectives in this field are also addressed.", "year": 2017, "publicationDate": "2017-12-06", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Materials Today", "pages": "164-177", "volume": "21"}, "citationCount": 171, "referenceCount": 208, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1016/j.mattod.2017.09.001", "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "12140923", "name": "Wei Wen"}, {"authorId": "35494004", "name": "Yang Song"}, {"authorId": "2110709619", "name": "Xu Yan"}, {"authorId": "4253234", "name": "Chengzhou Zhu"}, {"authorId": "144845419", "name": "Dan Du"}, {"authorId": "2151487564", "name": "Shengfu Wang"}, {"authorId": "152867916", "name": "Abdullah M. Asiri"}, {"authorId": "2033698", "name": "Yuehe Lin"}], "url": "https://www.semanticscholar.org/paper/f525daa4f289f1d07441fbc29dabbc3827bfad7a", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "0634503b5affdcb0fb901da7dd02059e2bbdcd5a", "title": "Application of graphene-based materials in water purification: from the nanoscale to specific devices", "abstract": null, "year": 2018, "publicationDate": "2018-06-14", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Environmental science. Nano", "pages": "1264-1297", "volume": "5"}, "citationCount": 117, "referenceCount": 282, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "3992903", "name": "Kaijie Yang"}, {"authorId": "2152810855", "name": "Jun Wang"}, {"authorId": "1471353157", "name": "Xiaoxiao Chen"}, {"authorId": "2110999775", "name": "Qiang Zhao"}, {"authorId": "49232328", "name": "A. Ghaffar"}, {"authorId": "92633148", "name": "Baoliang Chen"}], "url": "https://www.semanticscholar.org/paper/0634503b5affdcb0fb901da7dd02059e2bbdcd5a", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f62be267cd34c7f699a9fe1b48a2c713daaef15f", "title": "A review of top-down and bottom-up synthesis methods for the production of graphene, graphene oxide and reduced graphene oxide", "abstract": null, "year": 2022, "publicationDate": "2022-08-01", "publicationTypes": ["Review"], "venue": "Journal of Materials Science", "journal": {"name": "Journal of Materials Science", "pages": "14543 - 14578", "volume": "57"}, "citationCount": 192, "referenceCount": 160, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2180647886", "name": "Adri'an Guti'errez-Cruz"}, {"authorId": "2258729845", "name": "Alicia Ruiz-Hernandez"}, {"authorId": "2180643244", "name": "José Fernando Vega-Clemente"}, {"authorId": "2180639560", "name": "Daniela Guadalupe Luna-Gazcón"}, {"authorId": "1398886062", "name": "J. Campos-Delgado"}], "url": "https://www.semanticscholar.org/paper/f62be267cd34c7f699a9fe1b48a2c713daaef15f", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "0d8f9107f3ea73dcb061aa0a686941d7db229e92", "title": "Electrically-Transduced Chemical Sensors Based on Two-Dimensional Nanomaterials.", "abstract": "Electrically-transduced sensors, with their simplicity and compatibility with standard electronic technologies, produce signals that can be efficiently acquired, processed, stored, and analyzed. Two dimensional (2D) nanomaterials, including graphene, phosphorene (BP), transition metal dichalcogenides (TMDCs), and others, have proven to be attractive for the fabrication of high-performance electrically-transduced chemical sensors due to their remarkable electronic and physical properties originating from their 2D structure. This review highlights the advances in electrically-transduced chemical sensing that rely on 2D materials. The structural components of such sensors are described, and the underlying operating principles for different types of architectures are discussed. The structural features, electronic properties, and surface chemistry of 2D nanostructures that dictate their sensing performance are reviewed. Key advances in the application of 2D materials, from both a historical and analytical perspective, are summarized for four different groups of analytes: gases, volatile compounds, ions, and biomolecules. The sensing performance is discussed in the context of the molecular design, structure-property relationships, and device fabrication technology. The outlook of challenges and opportunities for 2D nanomaterials for the future development of electrically-transduced sensors is also presented.", "year": 2019, "publicationDate": "2019-01-03", "publicationTypes": ["JournalArticle", "Review"], "venue": "Chemical Reviews", "journal": {"name": "Chemical reviews", "pages": "\n          478-598\n        ", "volume": "119 1"}, "citationCount": 610, "referenceCount": 948, "influentialCitationCount": 3, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Chemistry", "Medicine"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "144905651", "name": "Zheng Meng"}, {"authorId": "47320918", "name": "Robert M Stolz"}, {"authorId": "50346768", "name": "Lukasz Mendecki"}, {"authorId": "6065753", "name": "K. Mirica"}], "url": "https://www.semanticscholar.org/paper/0d8f9107f3ea73dcb061aa0a686941d7db229e92", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "bbe39ca73b4ffc268ea6d7198d6d511a64380c95", "title": "Ultrathin Two-Dimensional Nanomaterials.", "abstract": null, "year": 2015, "publicationDate": "2015-09-25", "publicationTypes": ["JournalArticle", "Review"], "venue": "ACS Nano", "journal": {"name": "ACS nano", "pages": "\n          9451-69\n        ", "volume": "9 10"}, "citationCount": 1861, "referenceCount": 185, "influentialCitationCount": 6, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1021/acsnano.5b05040", "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2108906761", "name": "Hua Zhang"}], "url": "https://www.semanticscholar.org/paper/bbe39ca73b4ffc268ea6d7198d6d511a64380c95", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "bcd897974aa5de91bc0df9d3634e2e087f3afb4c", "title": "Scalable 2D Hierarchical Porous Carbon Nanosheets for Flexible Supercapacitors with Ultrahigh Energy Density", "abstract": null, "year": 2018, "publicationDate": "2018-03-01", "publicationTypes": ["JournalArticle"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "30"}, "citationCount": 447, "referenceCount": 56, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "153200841", "name": "Lei Yao"}, {"authorId": "2152862719", "name": "Qin Wu"}, {"authorId": "51264729", "name": "Peixin Zhang"}, {"authorId": "2108123959", "name": "Junmin Zhang"}, {"authorId": "2410811166", "name": "Dongrui Wang"}, {"authorId": "9263136", "name": "Yongliang Li"}, {"authorId": "3209754", "name": "X. Ren"}, {"authorId": "11317377", "name": "Hongwei Mi"}, {"authorId": "1905572", "name": "Libo Deng"}, {"authorId": "48262958", "name": "Zijian Zheng"}], "url": "https://www.semanticscholar.org/paper/bcd897974aa5de91bc0df9d3634e2e087f3afb4c", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "460fca5e660170a60c8e58bd5a5cf729863cd786", "title": "Group 6 transition metal dichalcogenide nanomaterials: synthesis, applications and future perspectives.", "abstract": null, "year": 2018, "publicationDate": "2018-02-26", "publicationTypes": ["JournalArticle", "Review"], "venue": "Nanoscale Horizons", "journal": {"name": "Nanoscale horizons", "pages": "\n          90-204\n        ", "volume": "3 2"}, "citationCount": 282, "referenceCount": 1192, "influentialCitationCount": 10, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.1039/c7nh00137a", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "92277771", "name": "Morasae Samadi"}, {"authorId": "98272711", "name": "N. Sarikhani"}, {"authorId": "2024201350", "name": "Mohammad Zirak"}, {"authorId": "2108906761", "name": "Hua Zhang"}, {"authorId": "2315579889", "name": "Hao-Li Zhang"}, {"authorId": "40576957", "name": "A. Moshfegh"}], "url": "https://www.semanticscholar.org/paper/460fca5e660170a60c8e58bd5a5cf729863cd786", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "e819d5d8011c357f8dba23830c5afb21b2e4fa3b", "title": "Sandwiched Fe3O4/Carboxylate Graphene Oxide Nanostructures Constructed by Layer-by-Layer Assembly for Highly Efficient and Magnetically Recyclable Dye Removal", "abstract": null, "year": 2018, "publicationDate": "2018-01-02", "publicationTypes": [], "venue": null, "journal": {"name": "ACS Sustainable Chemistry & Engineering", "pages": "1279-1288", "volume": "6"}, "citationCount": 297, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Chemistry"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "144920295", "name": "Rong Guo"}, {"authorId": "7773255", "name": "T. Jiao"}, {"authorId": "12433658", "name": "Ruifei Li"}, {"authorId": "2144285515", "name": "Yan Chen"}, {"authorId": "15496855", "name": "Wanchun Guo"}, {"authorId": "92385688", "name": "Lexin Zhang"}, {"authorId": "46618811", "name": "Jingxin Zhou"}, {"authorId": "2062467", "name": "Qingrui Zhang"}, {"authorId": "2485859", "name": "Qiuming Peng"}], "url": "https://www.semanticscholar.org/paper/e819d5d8011c357f8dba23830c5afb21b2e4fa3b", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "d6f81c45f303094ea9f4c4234678afbbea5b9e74", "title": "Beyond graphene: Electrochemical sensors and biosensors for biomarkers detection.", "abstract": null, "year": 2017, "publicationDate": "2017-03-15", "publicationTypes": ["Review", "JournalArticle"], "venue": "Biosensors & bioelectronics", "journal": {"name": "Biosensors & bioelectronics", "pages": "\n          152-166\n        ", "volume": "89 Pt 1"}, "citationCount": 352, "referenceCount": 78, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "6589879", "name": "P. Bollella"}, {"authorId": "49244573", "name": "G. Fusco"}, {"authorId": "8617155", "name": "C. Tortolini"}, {"authorId": "5054712", "name": "Gabriella Sanzó"}, {"authorId": "49741309", "name": "G. Favero"}, {"authorId": "6225476", "name": "L. Gorton"}, {"authorId": "3511196", "name": "R. Antiochia"}], "url": "https://www.semanticscholar.org/paper/d6f81c45f303094ea9f4c4234678afbbea5b9e74", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f55502dcb058088bd6d2f69e5219c4dc44e493de", "title": "Rational Design of Carbon-Based 2D Nanostructures for Enhanced Photocatalytic CO2 Reduction: A Dimensionality Perspective.", "abstract": "Photocatalytic CO2 reduction is a revolutionary approach to solve imminent energy and environmental issues by replicating the ingenuity of nature. The past decade has witnessed an impetus in the rise of two-dimensional (2D) structure materials as advanced nanomaterials to boost photocatalytic activities. In particular, the use of 2D carbon-based materials is deemed as highly favorable, not only as a green material choice, but also due to their exceptional physicochemical and electrical properties. This review article presents a diverse range of alterations and compositions derived from 2D carbon-based nanomaterials, mainly graphene and graphitic carbon nitride (g-C3N4), which have remarkably ameliorated the photocatalytic CO2 performance. Herein, the rational design of the photocatalyst systems with consideration on the aspect of dimensionality and the resultant heterostructures at the interface are systematically analyzed to elucidate an insightful perspective on this pacey subject. Finally, a conclusion and outlook on the limitations and prospects of the cutting-edge research field are highlighted.", "year": 2020, "publicationDate": "2020-06-08", "publicationTypes": ["JournalArticle", "Review"], "venue": "Chemistry", "journal": {"name": "Chemistry"}, "citationCount": 128, "referenceCount": 275, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2792038", "name": "Wee‐Jun Ong"}, {"authorId": "14502357", "name": "L. K. Putri"}, {"authorId": "9179188", "name": "A. R. Mohamed"}], "url": "https://www.semanticscholar.org/paper/f55502dcb058088bd6d2f69e5219c4dc44e493de", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "0b6c3307f959e2a31b46b51be9a96bd2fda6505f", "title": "Enhanced photocatalytic activity at multidimensional interface of 1D-Bi2S3@2D-GO/3D-BiOI ternary nanocomposites for tetracycline degradation under visible-light.", "abstract": "Structural dimensionality and surface morphology are key properties that greatly affect the functionalities of materials. Herein, we report a synthesis of dimensionally coupled ternary nanocomposites from three-dimensional (3D) bismuth oxyiodide (BiOI), two-dimensional (2D) graphene oxide (GO), and one-dimensional (1D) bismuth sulfide (Bi2S3) nanomaterials for tetracycline degradation under visible-light irradiation. The 2%-Bi2S3@1%-GO/BiOI ternary nanocomposites show higher degradation efficiency than neat 3D-BiOI. The coupling of neat 1D-Bi2S3 with the 1%-GO/BiOI binary nanocomposite does not increase the specific surface area of the resulting 2%-Bi2S3@1%-GO/3D-BiOI ternary nanocomposite, but enhances notably its charge carrier separation and migration, according to the analysis of the higher photocurrent, smaller arc radius of the electrochemical impedance spectroscopy and lower photoluminescence intensity. The observed results suggest that the combination of dimensionally coupled composites provides a synergistic effect through an efficient charge transfer process. This work offers new insights into the design and construction of dimensionally coupled ternary nanocomposites for environmental remediation applications.", "year": 2020, "publicationDate": "2020-09-05", "publicationTypes": ["JournalArticle"], "venue": "Journal of Hazardous Materials", "journal": {"name": "Journal of hazardous materials", "pages": "\n          123868\n        ", "volume": "404 Pt B"}, "citationCount": 111, "referenceCount": 66, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "152656102", "name": "Malathi Arumugam"}, {"authorId": "117809403", "name": "Seung Jun Lee"}, {"authorId": "1840461833", "name": "Talshyn Begildayeva"}, {"authorId": "1840210584", "name": "S. S. Naik"}, {"authorId": "15584030", "name": "Yiseul Yu"}, {"authorId": "2143730019", "name": "Hyeyeon Lee"}, {"authorId": "12451468", "name": "J. Theerthagiri"}, {"authorId": "8486249", "name": "M. Y. Choi"}], "url": "https://www.semanticscholar.org/paper/0b6c3307f959e2a31b46b51be9a96bd2fda6505f", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "42fe8309338b0f3bd11fd38d6d8e9d85798eb9de", "title": "Two dimensional nanomaterials for flexible supercapacitors.", "abstract": null, "year": 2014, "publicationDate": "2014-04-22", "publicationTypes": ["JournalArticle", "Review"], "venue": "Chemical Society Reviews", "journal": {"name": "Chemical Society reviews", "pages": "\n          3303-23\n        ", "volume": "43 10"}, "citationCount": 1007, "referenceCount": 105, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2109627481", "name": "Xu Peng"}, {"authorId": "10261218", "name": "Lele Peng"}, {"authorId": "7513543", "name": "Changzheng Wu"}, {"authorId": "143744512", "name": "Yi Xie"}], "url": "https://www.semanticscholar.org/paper/42fe8309338b0f3bd11fd38d6d8e9d85798eb9de", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "455270809cd61dd52af304f258b3807a44a0a142", "title": "Innovation and discovery of graphene‐like materials via density‐functional theory computations", "abstract": null, "year": 2015, "publicationDate": "2015-09-01", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Wiley Interdisciplinary Reviews: Computational Molecular Science", "volume": "5"}, "citationCount": 230, "referenceCount": 111, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Chemistry"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "145315978", "name": "Qing Tang"}, {"authorId": "1697319", "name": "Zhen Zhou"}, {"authorId": "2029325792", "name": "Zhongfang Chen"}], "url": "https://www.semanticscholar.org/paper/455270809cd61dd52af304f258b3807a44a0a142", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "dc180dbfdb2e2f7bb0c4905c2ec478da9ef6a706", "title": "Recent advances of 3D graphene-based adsorbents for sample preparation of water pollutants: A review", "abstract": "Abstract Recently, the researches about graphene-materials as efficient adsorbents have been promoted from two-dimension (2D) to three-dimension (3D). Compared with 2D graphene-materials, 3D graphene-based macrostructures not only preserve the original properties of constituent monomers, but also possess new collective physiochemical properties, making them more attractive as versatile adsorbents in sample preparation. In this review, we will innovatively summarize the recently published various kinds of 3D graphene-based adsorbents from the angles of material type (including pure 3D graphene and decorated with different materials: atom/molecule, inorganic-nanomaterials, polymers, carbon-nanomaterials and hybrid-composite-materials). Furthermore, we will discuss their applications for removing of various water pollutants (oils and organic solvents, dyes, metal ions, drugs, endocrine-disrupting chemicals and others). At last, the challenges and future outlook of 3D graphene-based adsorbents will also be discussed.", "year": 2020, "publicationDate": "2020-08-01", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Chemical Engineering Journal", "pages": "124691", "volume": "393"}, "citationCount": 125, "referenceCount": 199, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "15387817", "name": "Houmei Liu"}, {"authorId": "46639046", "name": "H. Qiu"}], "url": "https://www.semanticscholar.org/paper/dc180dbfdb2e2f7bb0c4905c2ec478da9ef6a706", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "647742a97ed7452fa647426523272cb1b890f9bf", "title": "One-pot synthesis of hierarchical porous covalent organic frameworks and two-dimensional nanomaterials for selective removal of anionic dyes", "abstract": "Abstract Covalent organic frameworks (COFs) are new generation of porous materials constructed from light elements (such as carbon, oxygen and nitrogen) linked via covalent bonds. Herein, one-pot synthesis of the composite of a COF and two-dimensional (2D) nanomaterials (graphene oxide (GO), graphitic carbon nitride (g-C3N4), and boron nitride (BN)) was reported. Melamine is poly-condensed with terephthaldehyde in the presence of GO, g-C3N4, and BN leading to the formation of a series of highly cross-linked microporous hierarchical porous amine networks. The thermal behavior, surface morphology, and crystalline structure were studied using thermogravimetric analysis (TGA), differential thermal analysis (DTA), scanning electron microscopy (SEM), X-ray diffraction (XRD), and transmission electron microscopy (TEM). The prepared COF nanocomposites possessed a high surface area of 42-509 m2 g−1 with a hierarchical porous structure and high thermal stability. COF nanocomposites (COF@GO, COF@g-C3N4, and COF@BN) were explored as an adsorbent for dye removal anionic dyes (Eosin dye and fluorescein) and cationic dyes (Fuchsine, and methylene blue). The composite materials exhibit high adsorption efficiency of 100% with excellent selectivity compared to the pristine COF. The synergic effect of COF and 2D nanomaterials improves the adsorption performance of the materials.", "year": 2020, "publicationDate": "2020-10-01", "publicationTypes": [], "venue": "Journal of Environmental Chemical Engineering", "journal": {"name": "Journal of Environmental Chemical Engineering"}, "citationCount": 110, "referenceCount": 81, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "95018753", "name": "Ahmed R. Abdellah"}, {"authorId": "13980668", "name": "H. N. Abdelhamid"}, {"authorId": "1412690710", "name": "Abu-Bakr A. El-Adasy"}, {"authorId": "92270904", "name": "A. Atalla"}, {"authorId": "46212670", "name": "K. Aly"}], "url": "https://www.semanticscholar.org/paper/647742a97ed7452fa647426523272cb1b890f9bf", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "657ab86e874a4abacb48b3a85cbb57730d0b3fe1", "title": "Electrical Property of Graphene and Its Application to Electrochemical Biosensing", "abstract": "Graphene, a single atom thick layer of two-dimensional closely packed honeycomb carbon lattice, and its derivatives have attracted much attention in the field of biomedical, due to its unique physicochemical properties. The valuable physicochemical properties, such as high surface area, excellent electrical conductivity, remarkable biocompatibility and ease of surface functionalization have shown great potentials in the applications of graphene-based bioelectronics devices, including electrochemical biosensors for biomarker analysis. In this review, we will provide a selective overview of recent advances on synthesis methods of graphene and its derivatives, as well as its application to electrochemical biosensor development. We believe the topics discussed here are useful, and able to provide a guideline in the development of novel graphene and on graphene-like 2-dimensional (2D) materials based biosensors in the future.", "year": 2019, "publicationDate": "2019-02-01", "publicationTypes": ["Review", "JournalArticle"], "venue": "Nanomaterials", "journal": {"name": "Nanomaterials", "volume": "9"}, "citationCount": 116, "referenceCount": 97, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2079-4991/9/2/297/pdf?version=1550764662", "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2144726910", "name": "Jin-Ho Lee"}, {"authorId": "2115424985", "name": "Soo-jeong Park"}, {"authorId": "6291275", "name": "Jeong-woo Choi"}], "url": "https://www.semanticscholar.org/paper/657ab86e874a4abacb48b3a85cbb57730d0b3fe1", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "0cc752b556a0579ff0446c718efcdcd3c75ab136", "title": "Graphene nanosheet: synthesis, molecular engineering, thin film, hybrids, and energy and analytical applications.", "abstract": null, "year": 2011, "publicationDate": "2011-04-18", "publicationTypes": ["JournalArticle", "Review"], "venue": "Chemical Society Reviews", "journal": {"name": "Chemical Society reviews", "pages": "\n          2644-72\n        ", "volume": "40 5"}, "citationCount": 1224, "referenceCount": 308, "influentialCitationCount": 9, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Physics"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2680624", "name": "Shaojun Guo"}, {"authorId": "144600811", "name": "S. Dong"}], "url": "https://www.semanticscholar.org/paper/0cc752b556a0579ff0446c718efcdcd3c75ab136", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "9490800b8be89c0cb74e443111edfea91a7f2e37", "title": "Hierarchical nanocomposites of polyaniline nanowire arrays on graphene oxide sheets with synergistic effect for energy storage.", "abstract": null, "year": 2010, "publicationDate": "2010-08-26", "publicationTypes": ["JournalArticle"], "venue": "ACS Nano", "journal": {"name": "ACS nano", "pages": "\n          5019-26\n        ", "volume": "4 9"}, "citationCount": 1312, "referenceCount": 40, "influentialCitationCount": 5, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2212229063", "name": "Jingjing Xu"}, {"authorId": "2148896887", "name": "Kai Wang"}, {"authorId": "12501459", "name": "Sheng-Zhen Zu"}, {"authorId": "152672110", "name": "Bao-Hang Han"}, {"authorId": "38020097", "name": "Zhixiang Wei"}], "url": "https://www.semanticscholar.org/paper/9490800b8be89c0cb74e443111edfea91a7f2e37", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f733c6c88d55e3f25c685989ac9f8757a9206c5a", "title": "Two‐Dimensional Nanostructured Materials for Gas Sensing", "abstract": null, "year": 2017, "publicationDate": "2017-10-01", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Advanced Functional Materials", "volume": "27"}, "citationCount": 734, "referenceCount": 317, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2144224300", "name": "Xianghong Liu"}, {"authorId": "1498525888", "name": "Tiantian Ma"}, {"authorId": "1819953", "name": "N. Pinna"}, {"authorId": "47540457", "name": "Jun Zhang"}], "url": "https://www.semanticscholar.org/paper/f733c6c88d55e3f25c685989ac9f8757a9206c5a", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "3335cd593cbf1c6fcc17d2d9c24890f9dc9451eb", "title": "Cytotoxicity evaluation of oxidized single-walled carbon nanotubes and graphene oxide on human hepatoma HepG2 cells: an iTRAQ-coupled 2D LC-MS/MS proteome analysis.", "abstract": null, "year": 2012, "publicationDate": "2012-03-01", "publicationTypes": ["JournalArticle", "Study"], "venue": "Toxicological Sciences", "journal": {"name": "Toxicological sciences : an official journal of the Society of Toxicology", "pages": "\n          149-61\n        ", "volume": "126 1"}, "citationCount": 134, "referenceCount": 42, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://academic.oup.com/toxsci/article-pdf/126/1/149/16684646/kfr332.pdf", "fieldsOfStudy": ["Medicine", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "114409488", "name": "Jifeng Yuan"}, {"authorId": "13934955", "name": "Hongcai Gao"}, {"authorId": "13698953", "name": "J. Sui"}, {"authorId": "143963315", "name": "Hongwei Duan"}, {"authorId": "31834719", "name": "W. N. Chen"}, {"authorId": "5902187", "name": "C. Ching"}], "url": "https://www.semanticscholar.org/paper/3335cd593cbf1c6fcc17d2d9c24890f9dc9451eb", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "fc9635b6f1272c58253492eb8e1854f45a28122e", "title": "V2O5-Based nanomaterials: synthesis and their applications", "abstract": "As an important part of lithium-ion batteries, the cathode material can directly affect the performance of lithium-ion batteries. However, with the increasing demand for high-energy and high-power devices, the energy and power density of electrode materials need to be further improved. Among all metal oxides, vanadium pentoxide (V2O5) is regarded as a promising candidate to serve as a cathode material for LIBs due to its high theoretical capacity. Herein, a thorough survey of the synthesis of V2O5-based nanomaterials with various structures and chemical compositions and their application as positive electrodes for LIBs is provided. This review covers V2O5 with different morphologies ranging from 1D nanorods/nanowires/nanotubes/nanofibers/nanobelts, to 2D nanosheets, and to 3D hollow and porous nanostructures. Nanocomposites consisting of V2O5 and different carbonaceous supports, e.g., amorphous carbon, carbon nanotubes, and graphene, are also investigated. The cation-doped V2O5 samples as the cathode material for LIBs are briefly discussed as well. The aim of this review is to provide an in-depth and rational understanding of how the electrochemical properties of V2O5-based cathodes can be effectively enhanced by achieving proper nanostructures with optimized chemical composition.", "year": 2018, "publicationDate": "2018-01-19", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "RSC Advances", "pages": "4014-4031", "volume": "8"}, "citationCount": 121, "referenceCount": 162, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://pubs.rsc.org/en/content/articlepdf/2018/ra/c7ra12523b", "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "2108736340", "name": "Xuyan Liu"}, {"authorId": "2047494049", "name": "Jia Zeng"}, {"authorId": "20736754", "name": "Huinan Yang"}, {"authorId": "2000821004", "name": "Kai Zhou"}, {"authorId": "144120978", "name": "Deng Pan"}], "url": "https://www.semanticscholar.org/paper/fc9635b6f1272c58253492eb8e1854f45a28122e", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "83aeaf1f0a95314cabd91411798c686e5323d326", "title": "Graphene Oxide Liquid Crystals: Discovery, Evolution and Applications", "abstract": null, "year": 2016, "publicationDate": "2016-04-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "28"}, "citationCount": 234, "referenceCount": 130, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Chemistry", "Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "5517602", "name": "Rekha Narayan"}, {"authorId": "2160107733", "name": "Ji Eun Kim"}, {"authorId": "47964826", "name": "J. ·. Kim"}, {"authorId": "2115395388", "name": "K. Lee"}, {"authorId": "2155564681", "name": "Sang Ouk Kim"}], "url": "https://www.semanticscholar.org/paper/83aeaf1f0a95314cabd91411798c686e5323d326", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "0df7703509f47d7ea986942f0afe465d8ee2be72", "title": "Two‐Dimensional Soft Nanomaterials: A Fascinating World of Materials", "abstract": null, "year": 2015, "publicationDate": "2015-03-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "27"}, "citationCount": 462, "referenceCount": 203, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "40121455", "name": "Xiaodong Zhuang"}, {"authorId": "1990875", "name": "Yiyong Mai"}, {"authorId": "1829742", "name": "Dongqing Wu"}, {"authorId": "2152987078", "name": "Fan Zhang"}, {"authorId": "143973487", "name": "Xinliang Feng"}], "url": "https://www.semanticscholar.org/paper/0df7703509f47d7ea986942f0afe465d8ee2be72", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "cd5a1ec4a1e73ca162340a67413f8e5dea7827d4", "title": "Development of asymmetric supercapacitors with titanium carbide-reduced graphene oxide couples as electrodes", "abstract": null, "year": 2018, "publicationDate": null, "publicationTypes": [], "venue": null, "journal": {"name": "Electrochimica Acta", "pages": "752-761", "volume": "259"}, "citationCount": 116, "referenceCount": 47, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/am/pii/S0013468617322478", "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "1401995097", "name": "A. M. Navarro‐Suárez"}, {"authorId": "92937895", "name": "K. L. Aken"}, {"authorId": "40129693", "name": "Tyler S. Mathis"}, {"authorId": "46478956", "name": "T. Makaryan"}, {"authorId": "2112592178", "name": "Jun Yan"}, {"authorId": "87986302", "name": "J. Carretero‐González"}, {"authorId": "49067319", "name": "T. Rojo"}, {"authorId": "144061594", "name": "Y. Gogotsi"}], "url": "https://www.semanticscholar.org/paper/cd5a1ec4a1e73ca162340a67413f8e5dea7827d4", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "eb936ae597ccb11c48e98ad15e7242299aa91bbd", "title": "A mixed-solvent strategy for efficient exfoliation of inorganic graphene analogues.", "abstract": "Layered two-dimensional (2D) nanomaterials such as graphene are a conceptually new class of materials that offers new access to low-dimensional physics. Besides wellknown graphene, inorganic graphene analogues (IGAs) such as layered transition metal dichalcogenides (e.g., MoS2 and WS2) [5–7] and boron nitride (BN) have been attracting rapidly increasing attention in the past few years. These IGAs were expected to exhibit unique properties and have great potential in applications like transistors, energy storage, thermal conductors, and topological insulators. Moreover, IGAs like MoS2 and WS2 have intrinsic band gap and high mobility, and may even compete with graphene in certain fields. However, investigations on IGAs have been significantly hindered by the practical difficulties in the preparation and assembly of these 2D nanomaterials. Only a few approaches to obtain few-layered IGAs have been reported. Mechanical exfoliation was first used to obtain layered IGAs from their bulk materials. Other approaches that are being explored include chemical synthesis and liquid exfoliation. Coleman et al. recently reported a surfactant-free liquid-exfoliation method which can produce few-layered nanosheets of IGAs dispersed in various organic solvents. Thermodynamic analysis suggested that, because of the high surface energy of IGAs, the best solvents are likely to have high boiling points. Using nonvolatile solvents makes it difficult to process IGAs into devices, due to the difficulties in the removal of solvent and the occurrence of aggregation during the slow solvent evaporation. To date, liquid exfoliation of layered MoS2 and WS2 in volatile solvent has met with very limited success. Herein we demonstrate a versatile and scaleable mixedsolvent strategy for liquid exfoliation of IGAs, including WS2, MoS2, and BN, in volatile solvents. By choosing solvents with appropriate composition, highly stable IGA suspensions can be obtained in low-boiling solvent mixtures, which can then be easily used in further applications. The dispersion of nanomaterials in liquids can be partially predicted by the theory of Hansen solubility parameters (HSP), which is a semi-empirical correlation developed to explain dissolution behavior. Three HSP parameters are used to describe the character of a solvent or material: dD, dP, and dH, which are the dispersive, polar, and hydrogen-bonding solubility parameters, respectively. The dissolution process is one of adaptation between the HSP parameters of solvents and solutes. The HSP distance Ra is used to evaluate the level of adaptation [Eq. (1)].", "year": 2011, "publicationDate": "2011-11-11", "publicationTypes": ["JournalArticle"], "venue": "Angewandte Chemie", "journal": {"name": "Angewandte Chemie", "pages": "\n          10839-42\n        ", "volume": "50 46"}, "citationCount": 904, "referenceCount": 30, "influentialCitationCount": 6, "isOpenAccess": true, "openAccessPdfUrl": "http://202.201.7.4:8080/handle/262010/75898", "fieldsOfStudy": ["Medicine"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "9368094", "name": "Kai-Ge Zhou"}, {"authorId": "32585571", "name": "Nan-nan Mao"}, {"authorId": "9840677", "name": "Hang-Xing Wang"}, {"authorId": "2110679392", "name": "Yong Peng"}, {"authorId": "2315579689", "name": "Hao-Li Zhang"}], "url": "https://www.semanticscholar.org/paper/eb936ae597ccb11c48e98ad15e7242299aa91bbd", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "f00904a32ae9926644081a838d702626e7af627b", "title": "Synthesis of Two‐Dimensional Materials for Capacitive Energy Storage", "abstract": null, "year": 2016, "publicationDate": "2016-08-01", "publicationTypes": ["JournalArticle"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "28"}, "citationCount": 561, "referenceCount": 197, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://www.osti.gov/biblio/1286986", "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "1401325335", "name": "Beatriz Mendoza‐Sánchez"}, {"authorId": "144061594", "name": "Y. Gogotsi"}], "url": "https://www.semanticscholar.org/paper/f00904a32ae9926644081a838d702626e7af627b", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "7fcc6af90c920f456531bf7053b6b420753cbe6e", "title": "SnO₂-based nanomaterials: synthesis and application in lithium-ion batteries.", "abstract": null, "year": 2013, "publicationDate": "2013-06-10", "publicationTypes": ["JournalArticle", "Review"], "venue": "Small", "journal": {"name": "Small", "pages": "\n          1877-93\n        ", "volume": "9 11"}, "citationCount": 702, "referenceCount": 213, "influentialCitationCount": 5, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Materials Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "27755919", "name": "J. Chen"}, {"authorId": "6012181", "name": "X. Lou"}], "url": "https://www.semanticscholar.org/paper/7fcc6af90c920f456531bf7053b6b420753cbe6e", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "ced07d0fe51ddc4286dbdf7b95357014a16b55b7", "title": "25th Anniversary Article: Hybrid Nanostructures Based on Two‐Dimensional Nanomaterials", "abstract": null, "year": 2014, "publicationDate": "2014-04-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "26"}, "citationCount": 569, "referenceCount": 264, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science", "Chemistry"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2107968965", "name": "Xiao Huang"}, {"authorId": "35221478", "name": "Chaoliang Tan"}, {"authorId": "4672378", "name": "Z. Yin"}, {"authorId": "66369860", "name": "Hua Zhang"}], "url": "https://www.semanticscholar.org/paper/ced07d0fe51ddc4286dbdf7b95357014a16b55b7", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "46e1a5562d135ddde50fce043e1e4fef381781b9", "title": "Purity of graphene oxide determines its antibacterial activity", "abstract": "Nanomaterials based on two-dimensional (2D) atomic crystals are considered to be very promising for various life-science and medical applications, from drug delivery to tissue modification. One of the most suitable materials for these purposes is graphene oxide (GO), thanks to a well-developed methods of production and water solubility. At the same time, its biological effect is still debated. Here we demonstrate that highly purified and thoroughly washed GO neither inhibited nor stimulated the growth of E.coli, ATCC25922; E.coli NCIMB11943 and S.aureus ATCC25923 at concentrations of up to 1 mg ml−1. Moreover, transmission electron microscopy (TEM) of GO exposed bacteria did not reveal any differences between GO exposed and not exposed populations. In contrast, a suspension of insufficiently purified GO behaved as an antibacterial material due to the presence of soluble acidic impurities, that could be removed by extended purification or neutralisation by alkaline substrates. A standardised protocol is proposed for the generation of clean GO, so it becomes suitable for biological experiments. Our findings emphasise the importance of GO purification status when dealing with biological systems as the true effect of material can be masked by the impact of impurities.", "year": 2016, "publicationDate": "2016-05-13", "publicationTypes": [], "venue": null, "journal": {"name": "2D Materials", "volume": "3"}, "citationCount": 169, "referenceCount": 46, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://iopscience.iop.org/article/10.1088/2053-1583/3/2/025025/pdf", "fieldsOfStudy": ["Physics", "Chemistry"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Biology", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "82327528", "name": "I. Barbolina"}, {"authorId": "47701509", "name": "C. Woods"}, {"authorId": "144266051", "name": "N. Lozano"}, {"authorId": "2985937", "name": "Kostas Kostarelos"}, {"authorId": "49912197", "name": "K. Novoselov"}, {"authorId": "143886906", "name": "I. Roberts"}], "url": "https://www.semanticscholar.org/paper/46e1a5562d135ddde50fce043e1e4fef381781b9", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "dc20d190e1073a08fdb2ca9a1dfb78b48163409e", "title": "From two-dimensional materials to their heterostructures: An electrochemist's perspective", "abstract": "Abstract Two-dimensional (2D) materials have, within just one decade, reshaped many disciplines of modern science and technology, both through intensive fundamental research and early commercial applications. In this review, we will provide a comprehensive summary of the properties, synthesis, characterisation, and application of 2D materials in the context of electrochemistry and related scientific fields. Firstly, the structural, electronic, optical, and mechanical properties, and a variety of preparation and characterisation techniques of 2D materials are presented. Secondly, current electrochemical understanding of 2D and layered materials and their modification is discussed. Lastly, future perspectives and new frontiers in optoelectronics, photocatalysis, and renewable energy using 2D materials are outlined. Our primary focus is on group 6 transition metal dichalcogenides (TMDCs) and other emerging 2D materials beyond graphene, including their heterostructures. These nanomaterials are essential for the next generation of devices in tuneable electrochemistry, sensing, and photovoltaics. Although broad in scope, this review is not an exhaustive list of facts; rather, it summarises the established knowledge and pinpoints the most promising future trends. It is aimed at readers with background in electrochemistry wanting to broaden their perspective or initiate research on 2D materials as well as those with 2D materials expertise looking to work on electrochemistry-based applications, such as energy storage and conversion.", "year": 2017, "publicationDate": "2017-09-01", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Applied Materials Today", "pages": "68-103", "volume": "8"}, "citationCount": 260, "referenceCount": 385, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://ars.els-cdn.com/content/image/1-s2.0-S235294071730080X-fx1_lrg.jpg", "fieldsOfStudy": ["Materials Science"], "s2FieldsOfStudy": [{"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "5368329", "name": "Matěj Velický"}, {"authorId": "4756757", "name": "P. Tóth"}], "url": "https://www.semanticscholar.org/paper/dc20d190e1073a08fdb2ca9a1dfb78b48163409e", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "1332cb634b3f9e5c003edd77f2f279d5754685d1", "title": "Tuning the Electrochemical Reactivity of Boron‐ and Nitrogen‐Substituted Graphene", "abstract": null, "year": 2016, "publicationDate": "2016-08-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "28"}, "citationCount": 118, "referenceCount": 67, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "3266418", "name": "Jingjie Wu"}, {"authorId": "123128913", "name": "M. Rodrigues"}, {"authorId": "5312544", "name": "R. Vajtai"}, {"authorId": "2514649", "name": "P. Ajayan"}], "url": "https://www.semanticscholar.org/paper/1332cb634b3f9e5c003edd77f2f279d5754685d1", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "3c443a4cf74fd28f3a61580b4517d13e563aad4d", "title": "Layer-by-Layer Assembly for Graphene-Based Multilayer Nanocomposites: Synthesis and Applications", "abstract": null, "year": 2015, "publicationDate": "2015-05-14", "publicationTypes": ["Review"], "venue": null, "journal": {"name": "Chemistry of Materials", "pages": "3785-3796", "volume": "27"}, "citationCount": 246, "referenceCount": 101, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Chemistry", "Materials Science"], "s2FieldsOfStudy": [{"category": "Chemistry", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "46963195", "name": "Taemin Lee"}, {"authorId": "8972902", "name": "S. Min"}, {"authorId": "21436141", "name": "Minsu Gu"}, {"authorId": "143795581", "name": "Y. Jung"}, {"authorId": "6214678", "name": "Wonoh Lee"}, {"authorId": "15073232", "name": "Jea-Uk Lee"}, {"authorId": "4349488", "name": "D. Seong"}, {"authorId": "5636284", "name": "Byeong‐Su Kim"}], "url": "https://www.semanticscholar.org/paper/3c443a4cf74fd28f3a61580b4517d13e563aad4d", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "af7c0b2dbdb88e81a89b4b311cdc0454134d9c1c", "title": "Nitrogen‐Doped Holey Graphitic Carbon from 2D Covalent Organic Polymers for Oxygen Reduction", "abstract": null, "year": 2014, "publicationDate": "2014-05-01", "publicationTypes": ["JournalArticle"], "venue": "Advances in Materials", "journal": {"name": "Advanced Materials", "volume": "26"}, "citationCount": 310, "referenceCount": 39, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Medicine", "Materials Science"], "s2FieldsOfStudy": [{"category": "Medicine", "source": "external"}, {"category": "Materials Science", "source": "external"}, {"category": "Materials Science", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}], "authors": [{"authorId": "8151427", "name": "Zhonghua Xiang"}, {"authorId": "2897468", "name": "D. Cao"}, {"authorId": "1500553550", "name": "Ling Huang"}, {"authorId": "5198854", "name": "J. Shui"}, {"authorId": "91692181", "name": "Min Wang"}, {"authorId": "145252070", "name": "L. Dai"}], "url": "https://www.semanticscholar.org/paper/af7c0b2dbdb88e81a89b4b311cdc0454134d9c1c", "_run_id": "4pIfHEeAkQZPUdU7m", "_dataset_id": "KDpFpTEBl30hPgVsn"}
{"paperId": "b0ff97b57ec911d06f36f20cb736fc6b4cee648a", "title": "Quantum Computing for Automotive Applications: From Algorithms to Applications", "abstract": "Quantum computing could impact various industries, with the automotive industry with many computational challenges, from optimizing supply chains and manufacturing to vehicle engineering, being particularly promising. This chapter investigates state-of-the-art quantum algorithms to enhance efficiency, accuracy, and scalability across the automotive value chain. We explore recent advances in quantum optimization, machine learning, and numerical and chemistry simulations, highlighting their potential and limitations. We identify and discuss key challenges in near-term and fault-tolerant algorithms and their practical use in industrial applications. While quantum algorithms show potential in many application domains, current noisy intermediate-scale quantum hardware limits scale and, thus, business benefits. In the long term, fault-tolerant systems promise theoretical speedups; however, they also require further progress in hardware and software (e.g., related to error correction and data loading). We expect that with this progress, significant practical benefits will emerge eventually.", "year": 2024, "publicationDate": "2024-09-21", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.14183"}, "citationCount": 2, "referenceCount": 207, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2322447168", "name": "B. G. Q. T. -. C. A. Riofr'io"}, {"authorId": "9653883", "name": "Johannes Klepsch"}, {"authorId": "2147184066", "name": "Jernej Rudi Finžgar"}, {"authorId": "2216606578", "name": "Florian J. Kiwit"}, {"authorId": "2308274239", "name": "Leonhard Holscher"}, {"authorId": "2140325675", "name": "Marvin Erdmann"}, {"authorId": "2374155549", "name": "Lukas Muller"}, {"authorId": "2392911577", "name": "Chandan Kumar"}, {"authorId": "2292312388", "name": "André Luckow"}], "url": "https://www.semanticscholar.org/paper/b0ff97b57ec911d06f36f20cb736fc6b4cee648a", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "aa91953c200d44a458a97f2ceb43becb84a900f8", "title": "Quantum Computing for Power Flow Algorithms: Testing on real Quantum Computers", "abstract": "Quantum computing has the potential to solve many computational problems exponentially faster than classical computers. The high shares of renewables and the wide deployment of converter-interfaced resources require new tools that shall drastically accelerate power system computations, including optimization and security assessment, which can benefit from quantum computing. To the best of our knowledge, this is the first paper that goes beyond quantum computing simulations and performs an experimental application of Quantum Computing for power systems on a real quantum computer. We use five different quantum computers, apply the HHL quantum algorithm, and examine the impact of current noisy quantum hardware on the accuracy and speed of an AC power flow algorithm. We perform the same studies on a 3-bus and a 5-bus system with real quantum computers to identify challenges and open research questions related with the scalability of these algorithms.", "year": 2022, "publicationDate": "2022-04-29", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2204.14028"}, "citationCount": 36, "referenceCount": 13, "influentialCitationCount": 5, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2204.14028", "fieldsOfStudy": ["Computer Science", "Physics", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2160557856", "name": "Brynjar Sævarsson"}, {"authorId": "2090253", "name": "Spyros Chatzivasileiadis"}, {"authorId": "40645973", "name": "H. Jóhannsson"}, {"authorId": "2164043990", "name": "Jacob Østergaard"}], "url": "https://www.semanticscholar.org/paper/aa91953c200d44a458a97f2ceb43becb84a900f8", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "9581b7564993b48f7788e668efd5ccd7c32e0eb1", "title": "QOPTLib: a Quantum Computing Oriented Benchmark for Combinatorial Optimization Problems", "abstract": "In this paper, we propose a quantum computing oriented benchmark for combinatorial optimization. This benchmark, coined as QOPTLib, is composed of 40 instances equally distributed over four well-known problems: Traveling Salesman Problem, Vehicle Routing Problem, one-dimensional Bin Packing Problem and the Maximum Cut Problem. The sizes of the instances in QOPTLib not only correspond to computationally addressable sizes, but also to the maximum length approachable with non-zero likelihood of getting a good result. In this regard, it is important to highlight that hybrid approaches are also taken into consideration. Thus, this benchmark constitutes the first effort to provide users a general-purpose dataset. Also in this paper, we introduce a first full solving of QOPTLib using two solvers based on quantum annealing. Our main intention with this is to establish a preliminary baseline, hoping to inspire other researchers to beat these outcomes with newly proposed quantum-based algorithms.", "year": 2024, "publicationDate": "2024-04-24", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2404.15852"}, "citationCount": 21, "referenceCount": 81, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2404.15852", "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2238024", "name": "E. Osaba"}, {"authorId": "1399096304", "name": "Esther Villar-Rodriguez"}], "url": "https://www.semanticscholar.org/paper/9581b7564993b48f7788e668efd5ccd7c32e0eb1", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "0dc299ad951690ebaa0bee0c49d1bb0ed86c4cba", "title": "Quantum Computing-Enhanced Algorithm Unveils Novel Inhibitors for KRAS", "abstract": "The discovery of small molecules with therapeutic potential is a long-standing challenge in chemistry and biology. Researchers have increasingly leveraged novel computational techniques to streamline the drug development process to increase hit rates and reduce the costs associated with bringing a drug to market. To this end, we introduce a quantum-classical generative model that seamlessly integrates the computational power of quantum algorithms trained on a 16-qubit IBM quantum computer with the established reliability of classical methods for designing small molecules. Our hybrid generative model was applied to designing new KRAS inhibitors, a crucial target in cancer therapy. We synthesized 15 promising molecules during our investigation and subjected them to experimental testing to assess their ability to engage with the target. Notably, among these candidates, two molecules, ISM061-018-2 and ISM061-22, each featuring unique scaffolds, stood out by demonstrating effective engagement with KRAS. ISM061-018-2 was identified as a broad-spectrum KRAS inhibitor, exhibiting a binding affinity to KRAS-G12D at $1.4 \\mu M$. Concurrently, ISM061-22 exhibited specific mutant selectivity, displaying heightened activity against KRAS G12R and Q61H mutants. To our knowledge, this work shows for the first time the use of a quantum-generative model to yield experimentally confirmed biological hits, showcasing the practical potential of quantum-assisted drug discovery to produce viable therapeutics. Moreover, our findings reveal that the efficacy of distribution learning correlates with the number of qubits utilized, underlining the scalability potential of quantum computing resources. Overall, we anticipate our results to be a stepping stone towards developing more advanced quantum generative models in drug discovery.", "year": 2024, "publicationDate": "2024-02-13", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2402.08210"}, "citationCount": 21, "referenceCount": 65, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Medicine", "source": "s2-fos-model"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1404105650", "name": "Mohammad Ghazi Vakili"}, {"authorId": "2279731793", "name": "Christoph Gorgulla"}, {"authorId": "133638577", "name": "AkshatKumar Nigam"}, {"authorId": "2204162685", "name": "Dmitry Bezrukov"}, {"authorId": "2283932135", "name": "Daniel Varoli"}, {"authorId": "2242175938", "name": "Alex Aliper"}, {"authorId": "36061519", "name": "Daniil Polykovskiy"}, {"authorId": "2258329775", "name": "K. P. Das"}, {"authorId": "2243282675", "name": "Jamie Snider"}, {"authorId": "118911946", "name": "A. Lyakisheva"}, {"authorId": "2283933283", "name": "Ardalan Hosseini Mansob"}, {"authorId": "2117802710", "name": "Zhong Yao"}, {"authorId": "147040590", "name": "L. Bitar"}, {"authorId": "2283931983", "name": "E. Radchenko"}, {"authorId": "2200045614", "name": "Xiao Ding"}, {"authorId": "2284032281", "name": "Jinxin Liu"}, {"authorId": "2283938678", "name": "Fanye Meng"}, {"authorId": "2282203796", "name": "Feng Ren"}, {"authorId": "2284357545", "name": "Yudong Cao"}, {"authorId": "2243278665", "name": "Igor Štagljar"}, {"authorId": "2250025903", "name": "Alán Aspuru-Guzik"}, {"authorId": "2264824500", "name": "A. Zhavoronkov"}], "url": "https://www.semanticscholar.org/paper/0dc299ad951690ebaa0bee0c49d1bb0ed86c4cba", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "06f2deb1c98efeed01b2e3e372efc415bed89f8c", "title": "5 Year Update to the Next Steps in Quantum Computing", "abstract": "It has been 5 years since the Computing Community Consortium (CCC) Workshop on Next Steps in Quantum Computing, and significant progress has been made in closing the gap between useful quantum algorithms and quantum hardware. Yet much remains to be done, in particular in terms of mitigating errors and moving towards error-corrected machines. As we begin to transition from the Noisy-Intermediate Scale Quantum (NISQ) era to a future of fault-tolerant machines, now is an opportune time to reflect on how to apply what we have learned thus far and what research needs to be done to realize computational advantage with quantum machines.", "year": 2024, "publicationDate": "2024-01-26", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2403.08780"}, "citationCount": 11, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2254368368", "name": "K. Brown"}, {"authorId": "2257280532", "name": "Frederic T. Chong"}, {"authorId": "2291201989", "name": "Kaitlin N. Smith"}, {"authorId": "2248316923", "name": "T. Conte"}, {"authorId": "2280381059", "name": "Austin J. Adams"}, {"authorId": "2169974905", "name": "Aniket M. Dalvi"}, {"authorId": "2155525971", "name": "Christopher Kang"}, {"authorId": "2380610581", "name": "Josh Viszlai"}], "url": "https://www.semanticscholar.org/paper/06f2deb1c98efeed01b2e3e372efc415bed89f8c", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "cb068e0cb62778aef04ec7b84c477dc2307b8eaf", "title": "A Scalable FPGA Architecture for Quantum Computing Simulation", "abstract": "A quantum computing simulation provides the opportunity to explore the behaviors of quantum circuits, study the properties of quantum gates, and develop quantum computing algorithms. Simulating quantum circuits requires geometric time and space complexities, impacting the size of the quantum circuit that can be simulated as well as the respective time required to simulate a particular circuit. Applying the parallelism inherent in the simulation and crafting custom architectures, larger quantum circuits can be simulated. A scalable accelerator architecture is proposed to provide a high performance, highly parallel, accelerator. Among the challenges of creating a scalable architecture is managing parallelism, efficiently routing quantum state components for gate evaluation, and measurement. An example is demonstrated on an Intel Agilex field programmable gate array (FPGA).", "year": 2024, "publicationDate": "2024-07-08", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2407.06415"}, "citationCount": 4, "referenceCount": 30, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1723246", "name": "L. Belfore"}], "url": "https://www.semanticscholar.org/paper/cb068e0cb62778aef04ec7b84c477dc2307b8eaf", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "b7c1a3a3ea258436648255bd74954e703d4ffa57", "title": "Quantum Computing for Databases: Overview and Challenges", "abstract": "In the decades, the general field of quantum computing has experienced remarkable progress since its inception. A plethora of researchers not only proposed quantum algorithms showing the power of quantum computing but also constructed the prototype of quantum computers, making it walk into our tangible reality. Those remarkable advancements in quantum computing have opened doors for novel applications, one of which is quantum databases. Researchers are trying to use a paradigm brought by quantum computing to revolutionize various aspects of database management systems. In this paper, we envision the synergy between quantum computing and databases with two perspectives: Quantum computing-enabled technology, and quantum computing-inspired technology. Based on this classification, we present a detailed overview of the research attained in this area, aiming to show the landscape of the field and draw a road map of future directions.", "year": 2024, "publicationDate": "2024-05-21", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2405.12511"}, "citationCount": 4, "referenceCount": 124, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1998181160", "name": "Gongsheng Yuan"}, {"authorId": "2109167672", "name": "Yuxing Chen"}, {"authorId": "1680607", "name": "Jiaheng Lu"}, {"authorId": "2238892767", "name": "Sai Wu"}, {"authorId": "2295873434", "name": "Zhiwei Ye"}, {"authorId": "2294377756", "name": "Ling Qian"}, {"authorId": "2243329017", "name": "Gang Chen"}], "url": "https://www.semanticscholar.org/paper/b7c1a3a3ea258436648255bd74954e703d4ffa57", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "8150ff23270e16a3234ee5a8916844e20d2ed508", "title": "Generative AI-enabled Quantum Computing Networks and Intelligent Resource Allocation", "abstract": "Quantum computing networks enable scalable collaboration and secure information exchange among multiple classical and quantum computing nodes while executing large-scale generative AI computation tasks and advanced quantum algorithms. Quantum computing networks overcome limitations such as the number of qubits and coherence time of entangled pairs and offer advantages for generative AI infrastructure, including enhanced noise reduction through distributed processing and improved scalability by connecting multiple quantum devices. However, efficient resource allocation in quantum computing networks is a critical challenge due to factors including qubit variability and network complexity. In this article, we propose an intelligent resource allocation framework for quantum computing networks to improve network scalability with minimized resource costs. To achieve scalability in quantum computing networks, we formulate the resource allocation problem as stochastic programming, accounting for the uncertain fidelities of qubits and entangled pairs. Furthermore, we introduce state-of-the-art reinforcement learning (RL) algorithms, from generative learning to quantum machine learning for optimal quantum resource allocation to resolve the proposed stochastic resource allocation problem efficiently. Finally, we optimize the resource allocation in heterogeneous quantum computing networks supporting quantum generative learning applications and propose a multi-agent RL-based algorithm to learn the optimal resource allocation policies without prior knowledge.", "year": 2024, "publicationDate": "2024-01-13", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2401.07120"}, "citationCount": 4, "referenceCount": 15, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Engineering", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1454018677", "name": "Minrui Xu"}, {"authorId": "1713586", "name": "D. Niyato"}, {"authorId": "2261731446", "name": "Jiawen Kang"}, {"authorId": "2943819", "name": "Zehui Xiong"}, {"authorId": "2279668880", "name": "Yuan Cao"}, {"authorId": "3448082", "name": "Yulan Gao"}, {"authorId": "2220215894", "name": "Chao Ren"}, {"authorId": "2186151237", "name": "Han Yu"}], "url": "https://www.semanticscholar.org/paper/8150ff23270e16a3234ee5a8916844e20d2ed508", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "dba25628a0b4192a523004edbaae5c24d785fcfb", "title": "Machine Learning for Quantum Computing Specialists", "abstract": "Quantum machine learning (QML) is a promising early use case for quantum computing. There has been progress in the last five years from theoretical studies and numerical simulations to proof of concepts. Use cases demonstrated on contemporary quantum devices include classifying medical images and items from the Iris dataset, classifying and generating handwritten images, toxicity screening, and learning a probability distribution. Potential benefits of QML include faster training and identification of feature maps not found classically. Although, these examples lack the scale for commercial exploitation, and it may be several years before QML algorithms replace the classical solutions, QML is an exciting area. This article is written for those who already have a sound knowledge of quantum computing and now wish to gain a basic overview of the terminology and some applications of classical machine learning ready to study quantum machine learning. The reader will already understand the relevant relevant linear algebra, including Hilbert spaces, a vector space with an inner product.", "year": 2024, "publicationDate": "2024-04-29", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2404.18555"}, "citationCount": 3, "referenceCount": 21, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2298905590", "name": "Daniel Charles Goldsmith"}, {"authorId": "2298905903", "name": "M. Mahmud"}], "url": "https://www.semanticscholar.org/paper/dba25628a0b4192a523004edbaae5c24d785fcfb", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "0b8d36bc484903b00e63f9e8821ab6003e66bf00", "title": "A Quantum Computing Approach for Multi-robot Coverage Path Planning", "abstract": "This paper tackles the multi-vehicle Coverage Path Planning (CPP) problem, crucial for applications like search and rescue or environmental monitoring. Due to its NP-hard nature, finding optimal solutions becomes infeasible with larger problem sizes. This motivates the development of heuristic approaches that enhance efficiency even marginally. We propose a novel approach for exploring paths in a 2D grid, specifically designed for easy integration with the Quantum Alternating Operator Ansatz (QAOA), a powerful quantum heuristic. Our contribution includes: 1) An objective function tailored to solve the multi-vehicle CPP using QAOA. 2) Theoretical proofs guaranteeing the validity of the proposed approach. 3) Efficient construction of QAOA operators for practical implementation. 4) Resource estimation to assess the feasibility of QAOA execution. 5) Performance comparison against established algorithms like the Depth First Search. This work paves the way for leveraging quantum computing in optimizing multi-vehicle path planning, potentially leading to real-world advancements in various applications.", "year": 2024, "publicationDate": "2024-07-11", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2407.08767"}, "citationCount": 0, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2047423149", "name": "P. U. Rao"}, {"authorId": "2330518210", "name": "F. Speelman"}, {"authorId": "2453744", "name": "B. Sodhi"}, {"authorId": "2287370959", "name": "Sachin Kinge"}], "url": "https://www.semanticscholar.org/paper/0b8d36bc484903b00e63f9e8821ab6003e66bf00", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "74bea8e40d90029cc471decc525391e2f9a935ac", "title": "From Portfolio Optimization to Quantum Blockchain and Security: A Systematic Review of Quantum Computing in Finance", "abstract": "In this paper, we provide an overview of the recent work in the quantum finance realm from various perspectives. The applications in consideration are Portfolio Optimization, Fraud Detection, and Monte Carlo methods for derivative pricing and risk calculation. Furthermore, we give a comprehensive overview of the applications of quantum computing in the field of blockchain technology which is a main concept in fintech. In that sense, we first introduce the general overview of blockchain with its main cryptographic primitives such as digital signature algorithms, hash functions, and random number generators as well as the security vulnerabilities of blockchain technologies after the merge of quantum computers considering Shor's quantum factoring and Grover's quantum search algorithms. We then discuss the privacy preserving quantum-resistant blockchain systems via threshold signatures, ring signatures, and zero-knowledge proof systems i.e. ZK-SNARKs in quantum resistant blockchains. After emphasizing the difference between the quantum-resistant blockchain and quantum-safe blockchain we mention the security countermeasures to take against the possible quantumized attacks aiming these systems. We finalize our discussion with quantum blockchain, efficient quantum mining and necessary infrastructures for constructing such systems based on quantum computing. This review has the intention to be a bridge to fill the gap between quantum computing and one of its most prominent application realms: Finance. We provide the state-of-the-art results in the intersection of finance and quantum technology for both industrial practitioners and academicians.", "year": 2023, "publicationDate": "2023-06-12", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2307.01155"}, "citationCount": 45, "referenceCount": 189, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2307.01155", "fieldsOfStudy": ["Computer Science", "Economics", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Economics", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Business", "source": "s2-fos-model"}], "authors": [{"authorId": "101494134", "name": "A. Naik"}, {"authorId": "2007594481", "name": "Esra Yeniaras"}, {"authorId": "2132334122", "name": "Gerhard Hellstern"}, {"authorId": "2221012774", "name": "Grishma Prasad"}, {"authorId": "1998355", "name": "Sanjay Vishwakarma"}], "url": "https://www.semanticscholar.org/paper/74bea8e40d90029cc471decc525391e2f9a935ac", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "dc586195e20550dd4a3bc5ebabfb00f5441ee888", "title": "Efficient techniques to GPU Accelerations of Multi-Shot Quantum Computing Simulations", "abstract": "Quantum computers are becoming practical for computing numerous applications. However, simulating quantum computing on classical computers is still demanding yet useful because current quantum computers are limited because of computer resources, hardware limits, instability, and noises. Improving quantum computing simulation performance in classical computers will contribute to the development of quantum computers and their algorithms. Quantum computing simulations on classical computers require long performance times, especially for quantum circuits with a large number of qubits or when simulating a large number of shots for noise simulations or circuits with intermediate measures. Graphical processing units (GPU) are suitable to accelerate quantum computer simulations by exploiting their computational power and high bandwidth memory and they have a large advantage in simulating relatively larger qubits circuits. However, GPUs are inefficient at simulating multi-shots runs with noises because the randomness prevents highly parallelization. In addition, GPUs have a disadvantage in simulating circuits with a small number of qubits because of the large overheads in GPU kernel execution. In this paper, we introduce optimization techniques for multi-shot simulations on GPUs. We gather multiple shots of simulations into a single GPU kernel execution to reduce overheads by scheduling randomness caused by noises. In addition, we introduce shot-branching that reduces calculations and memory usage for multi-shot simulations. By using these techniques, we speed up x10 from previous implementations.", "year": 2023, "publicationDate": "2023-08-07", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2308.03399"}, "citationCount": 18, "referenceCount": 25, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2308.03399", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "3053086", "name": "J. Doi"}, {"authorId": "97725022", "name": "H. Horii"}, {"authorId": "2380038963", "name": "Christopher Wood"}], "url": "https://www.semanticscholar.org/paper/dc586195e20550dd4a3bc5ebabfb00f5441ee888", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "234cc2389cc16765eac5fc0dfd53f86f9e63f2c5", "title": "Expressing and Analyzing Quantum Algorithms with Qualtran", "abstract": "Quantum computing's transition from theory to reality has spurred the need for novel software tools to manage the increasing complexity, sophistication, toil, and fallibility of quantum algorithm development. We present Qualtran, an open-source library for representing and analyzing quantum algorithms. Using appropriate abstractions and data structures, we can simulate and test algorithms, automatically generate information-rich diagrams, and tabulate resource requirements. Qualtran offers a standard library of algorithmic building blocks that are essential for modern cost-minimizing compilations. Its capabilities are showcased through the re-analysis of key algorithms in Hamiltonian simulation, chemistry, and cryptography. Architecture-independent resource counts output by Qualtran can be forwarded to our implementation of cost models to estimate physical costs like wall-clock time and number of physical qubits assuming a surface-code architecture. Qualtran provides a foundation for explicit constructions and reproducible analysis, fostering greater collaboration within the growing quantum algorithm development community.", "year": 2024, "publicationDate": "2024-09-06", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.04643"}, "citationCount": 58, "referenceCount": 110, "influentialCitationCount": 6, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "8236814", "name": "M. Harrigan"}, {"authorId": "82403343", "name": "T. Khattar"}, {"authorId": "145564093", "name": "Charles Yuan"}, {"authorId": "2125715129", "name": "Anurudh Peduri"}, {"authorId": "2307518361", "name": "N. Yosri"}, {"authorId": "145839285", "name": "F. Malone"}, {"authorId": "47066334", "name": "R. Babbush"}, {"authorId": "34743111", "name": "N. Rubin"}], "url": "https://www.semanticscholar.org/paper/234cc2389cc16765eac5fc0dfd53f86f9e63f2c5", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "103500bdabd10004ebb99a485a10661684ee73cc", "title": "The Quantum Tortoise and the Classical Hare: A simple framework for understanding which problems quantum computing will accelerate (and which it will not)", "abstract": "Quantum computing promises transformational gains for solving some problems, but little to none for others. For anyone hoping to use quantum computers now or in the future, it is important to know which problems will benefit. In this paper, we introduce a framework for answering this question both intuitively and quantitatively. The underlying structure of the framework is a race between quantum and classical computers, where their relative strengths determine when each wins. While classical computers operate faster, quantum computers can sometimes run more efficient algorithms. Whether the speed advantage or the algorithmic advantage dominates determines whether a problem will benefit from quantum computing or not. Our analysis reveals that many problems, particularly those of small to moderate size that can be important for typical businesses, will not benefit from quantum computing. Conversely, larger problems or those with particularly big algorithmic gains will benefit from near-term quantum computing. Since very large algorithmic gains are rare in practice and theorized to be rare even in principle, our analysis suggests that the benefits from quantum computing will flow either to users of these rare cases, or practitioners processing very large data.", "year": 2023, "publicationDate": "2023-10-24", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2310.15505"}, "citationCount": 9, "referenceCount": 49, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Economics", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Economics", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2261565079", "name": "Sukwoong Choi"}, {"authorId": "2261391831", "name": "William S. Moses"}, {"authorId": "2261392348", "name": "Neil Thompson"}], "url": "https://www.semanticscholar.org/paper/103500bdabd10004ebb99a485a10661684ee73cc", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "156bb4acb0d4091f9bda42ea684fea9b21cc8988", "title": "Challenges for Reinforcement Learning in Quantum Computing", "abstract": null, "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2312.11337"}, "citationCount": 5, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2074355634", "name": "Philipp Altmann"}, {"authorId": "2275194168", "name": "Adelina Barligea"}, {"authorId": "2173870813", "name": "Jonas Stein"}, {"authorId": "2197075812", "name": "Michael Kolle"}, {"authorId": "1599420389", "name": "Thomas Gabor"}, {"authorId": "41021158", "name": "Thomy Phan"}, {"authorId": "1402371578", "name": "Claudia Linnhoff-Popien"}], "url": "https://www.semanticscholar.org/paper/156bb4acb0d4091f9bda42ea684fea9b21cc8988", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "771ae9d4135f44cf1aae3076be47099edfd20a8a", "title": "New Abstractions for Quantum Computing", "abstract": "The field of quantum computing is at an exciting time where we are constructing novel hardware, evaluating algorithms, and finding out what works best. As qubit technology grows and matures, we need to be ready to design and program larger quantum computer systems. An important aspect of systems design is layered abstractions to reduce complexity and guide intuition. Classical computer systems have built up many abstractions over their history including the layers of the hardware stack and programming abstractions like loops. Researchers initially ported these abstractions with little modification when designing quantum computer systems and only in recent years have some of those abstractions been broken in the name of optimization and efficiency. We argue that new or quantum-tailored abstractions are needed to get the most benefit out of quantum computer systems. We keep the benefits gained through breaking old abstraction by finding abstractions aligned with quantum physics and the technology. This dissertation is supported by three examples of abstractions that could become a core part of how we design and program quantum computers: third-level logical state as scratch space, memory as a third spacial dimension for quantum data, and hierarchical program structure.", "year": 2023, "publicationDate": "2023-03-05", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2303.02578"}, "citationCount": 2, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2303.02578", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "95842911", "name": "Casey Duckering"}], "url": "https://www.semanticscholar.org/paper/771ae9d4135f44cf1aae3076be47099edfd20a8a", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "2fbec202f97aa1c8e2a4da0dde3d52ce2007cc12", "title": "Minimizing Photonic Cluster State Depth in Measurement-Based Quantum Computing", "abstract": "Measurement-based quantum computing (MBQC) is a promising quantum computing paradigm that performs computation through ``one-way'' measurements on entangled quantum qubits. It is widely used in photonic quantum computing (PQC), where the computation is carried out on photonic cluster states (i.e., a 2-D mesh of entangled photons). In MBQC-based PQC, the cluster state depth (i.e., the length of one-way measurements) to execute a quantum circuit plays an important role in the overall execution time and error. Thus, it is important to reduce the cluster state depth. In this paper, we propose FMCC, a compilation framework that employs dynamic programming to efficiently minimize the cluster state depth. Experimental results on five representative quantum algorithms show that FMCC achieves 53.6%, 60.6%, and 60.0% average depth reductions in small, medium, and large qubit counts compared to the state-of-the-art MBQC compilation frameworks.", "year": 2023, "publicationDate": "2023-12-18", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2312.10865"}, "citationCount": 2, "referenceCount": 41, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2241676005", "name": "Yingheng Li"}, {"authorId": "2241596425", "name": "Aditya Pawar"}, {"authorId": "2275053944", "name": "Zewei Mo"}, {"authorId": "1686367", "name": "Youtao Zhang"}, {"authorId": "2241953831", "name": "Jun Yang"}, {"authorId": "2241946519", "name": "Xulong Tang"}], "url": "https://www.semanticscholar.org/paper/2fbec202f97aa1c8e2a4da0dde3d52ce2007cc12", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "5b0c79612ce5776479ca6f94638bb90cc248a089", "title": "Guess What Quantum Computing Can Do for Test Case Optimization", "abstract": null, "year": 2023, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2312.15547"}, "citationCount": 5, "referenceCount": 38, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2115553674", "name": "Xinyi Wang"}, {"authorId": "2249914761", "name": "Shaukat Ali"}, {"authorId": "145456500", "name": "T. Yue"}, {"authorId": "2122951953", "name": "Paolo Arcaini"}], "url": "https://www.semanticscholar.org/paper/5b0c79612ce5776479ca6f94638bb90cc248a089", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "59623424813be5ddd675674a70f21793474ee868", "title": "Quantum Computing for Solid Mechanics and Structural Engineering - a Demonstration with Variational Quantum Eigensolver", "abstract": "Variational quantum algorithms exploit the features of superposition and entanglement to optimize a cost function efficiently by manipulating the quantum states. They are suitable for noisy intermediate-scale quantum (NISQ) computers that recently became accessible to the worldwide research community. Here, we implement and demonstrate the numerical processes on the 5-qubit and 7-qubit quantum processors on the IBM Qiskit Runtime platform. We combine the commercial finite-element-method (FEM) software ABAQUS with the implementation of Variational Quantum Eigensolver (VQE) to establish an integrated pipeline. Three examples are used to investigate the performance: a hexagonal truss, a Timoshenko beam, and a plane-strain continuum. We conduct parametric studies on the convergence of fundamental natural frequency estimation using this hybrid quantum-classical approach. Our findings can be extended to problems with many more degrees of freedom when quantum computers with hundreds of qubits become available in the near future.", "year": 2023, "publicationDate": "2023-08-28", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2308.14745"}, "citationCount": 6, "referenceCount": 79, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2308.14745", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "119923800", "name": "Yunya Liu"}, {"authorId": "2361457747", "name": "Jiakun Liu"}, {"authorId": "143774770", "name": "J. Raney"}, {"authorId": "2193655302", "name": "Pai Wang"}], "url": "https://www.semanticscholar.org/paper/59623424813be5ddd675674a70f21793474ee868", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "ef35da3a3c471a6a15c7a3b09586483eb50cbef0", "title": "Practical application-specific advantage through hybrid quantum computing", "abstract": "Quantum computing promises to tackle technological and industrial problems insurmountable for classical computers. However, today's quantum computers still have limited demonstrable functionality, and it is expected that scaling up to millions of qubits is required for them to live up to this touted promise. The feasible route in achieving practical quantum advantage goals is to implement a hybrid operational mode that realizes the cohesion of quantum and classical computers. Here we present a hybrid quantum cloud based on a memory-centric and heterogeneous multiprocessing architecture, integrated into a high-performance computing data center grade environment. We demonstrate that utilizing the quantum cloud, our hybrid quantum algorithms including Quantum Encoding (QuEnc), Hybrid Quantum Neural Networks and Tensor Networks enable advantages in optimization, machine learning, and simulation fields. We show the advantage of hybrid algorithms compared to standard classical algorithms in both the computational speed and quality of the solution. The achieved advance in hybrid quantum hardware and software makes quantum computing useful in practice today.", "year": 2022, "publicationDate": "2022-05-10", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2205.04858"}, "citationCount": 39, "referenceCount": 95, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2205.04858", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "31347453", "name": "M. Perelshtein"}, {"authorId": "2087046300", "name": "A. Sagingalieva"}, {"authorId": "2164706014", "name": "Karan Pinto"}, {"authorId": "2557591", "name": "Vishal Shete"}, {"authorId": "1388013676", "name": "A. Pakhomchik"}, {"authorId": "2050228932", "name": "A. Melnikov"}, {"authorId": "2065938", "name": "F. Neukart"}, {"authorId": "2140212060", "name": "Georg Gesek"}, {"authorId": "47610941", "name": "A. Melnikov"}, {"authorId": "143700248", "name": "V. Vinokur"}], "url": "https://www.semanticscholar.org/paper/ef35da3a3c471a6a15c7a3b09586483eb50cbef0", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "bd30fc178d62ff0505d54cfa5274ef19c69809c3", "title": "Variational Quantum Algorithms for Combinatorial Optimization", "abstract": "The promise of quantum computing to address complex problems requiring high computational resources has long been hindered by the intrinsic and demanding requirements of quantum hardware development. Nonetheless, the current state of quantum computing, denominated Noisy Intermediate-Scale Quantum (NISQ) era, has introduced algorithms and methods that are able to harness the computational power of current quantum computers with advantages over classical computers (referred to as quantum advantage). Achieving quantum advantage is of particular relevance for the combinatorial optimization domain, since it often implies solving an NP-Hard optimization problem. Moreover, combinatorial problems are highly relevant for practical application areas, such as operations research, or resource allocation problems. Among quantum computing methods, Variational Quantum Algorithms (VQA) have emerged as one of the strongest candidates towards reaching practical applicability of NISQ systems. This paper explores the current state and recent developments of VQAs, emphasizing their applicability to combinatorial optimization. We identify the Quantum Approximate Optimization Algorithm (QAOA) as the leading candidate for these problems. Furthermore, we implement QAOA circuits with varying depths to solve the MaxCut problem on graphs with 10 and 20 nodes, demonstrating the potential and challenges of using VQAs in practical optimization tasks. We release our code, dataset and optimized circuit parameters under https://github.com/DanielFPerez/VQA-for-MaxCut.", "year": 2024, "publicationDate": "2024-07-08", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2407.06421"}, "citationCount": 18, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "1879112127", "name": "Daniel F. Pérez-Ramírez"}], "url": "https://www.semanticscholar.org/paper/bd30fc178d62ff0505d54cfa5274ef19c69809c3", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "83467420b4d112f63960abfa13a5a4f1f39b239e", "title": "QPanda: high-performance quantum computing framework for multiple application scenarios", "abstract": "With the birth of Noisy Intermediate Scale Quantum (NISQ) devices and the verification of\"quantum supremacy\"in random number sampling and boson sampling, more and more fields hope to use quantum computers to solve specific problems, such as aerodynamic design, route allocation, financial option prediction, quantum chemical simulation to find new materials, and the challenge of quantum cryptography to automotive industry security. However, these fields still need to constantly explore quantum algorithms that adapt to the current NISQ machine, so a quantum programming framework that can face multi-scenarios and application needs is required. Therefore, this paper proposes QPanda, an application scenario-oriented quantum programming framework with high-performance simulation. Such as designing quantum chemical simulation algorithms based on it to explore new materials, building a quantum machine learning framework to serve finance, etc. This framework implements high-performance simulation of quantum circuits, a configuration of the fusion processing backend of quantum computers and supercomputers, and compilation and optimization methods of quantum programs for NISQ machines. Finally, the experiment shows that quantum jobs can be executed with high fidelity on the quantum processor using quantum circuit compile and optimized interface and have better simulation performance.", "year": 2022, "publicationDate": "2022-12-29", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2212.14201"}, "citationCount": 27, "referenceCount": 50, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2212.14201", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2104448722", "name": "Menghan Dou"}, {"authorId": "2199028140", "name": "Tianrui Zou"}, {"authorId": "2112809567", "name": "Yuan Fang"}, {"authorId": "2152438844", "name": "Jing Wang"}, {"authorId": "145491312", "name": "Dongyi Zhao"}, {"authorId": "2112533140", "name": "Lei Yu"}, {"authorId": "2152692432", "name": "Boying Chen"}, {"authorId": "3138660", "name": "Wenbo Guo"}, {"authorId": "2117159447", "name": "Ye Li"}, {"authorId": "2111606340", "name": "Zhao-Yun Chen"}, {"authorId": "2067613615", "name": "G. Guo"}], "url": "https://www.semanticscholar.org/paper/83467420b4d112f63960abfa13a5a4f1f39b239e", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "c7931f4e9210c05be0685aa44c0cf29f407cc94e", "title": "Paint shop vehicle sequencing based on quantum computing considering color changeover and painting quality", "abstract": "As customer demands become increasingly diverse, the colors and styles of vehicles offered by automotive companies have also grown substantially. It poses great challenges to design and management of automotive manufacturing system, among which is the proper sequencing of vehicles in everyday operation of the paint shop. With typically hundreds of vehicles in one shift, the paint shop sequencing problem is intractable in classical computing. In this paper, we propose to solve a general paint shop sequencing problem using state-of-the-art quantum computing algorithms. Most existing works are solely focused on reducing color changeover costs, i.e., costs incurred by different colors between consecutive vehicles. This work reveals that different sequencing of vehicles also significantly affects the quality performance of the painting process. We use a machine learning model pretrained on historical data to predict the probability of painting defect. The problem is formulated as a combinational optimization problem with two cost components, i.e., color changeover cost and repair cost. The problem is further converted to a quantum optimization problem and solved with Quantum Approximation Optimization Algorithm (QAOA). As a matter of fact, current quantum computers are still limited in accuracy and scalability. However, with a simplified case study, we demonstrate how the classic sequencing problem in paint shop can be formulated and solved using quantum computing and demonstrate the potential of quantum computing in solving real problems in manufacturing systems.", "year": 2022, "publicationDate": "2022-06-22", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2206.11204"}, "citationCount": 2, "referenceCount": 19, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2206.11204", "fieldsOfStudy": ["Physics", "Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2145739073", "name": "Jing Huang"}, {"authorId": "115350139", "name": "H. Fan"}, {"authorId": "2430990", "name": "G. Xiao"}, {"authorId": "47586665", "name": "Q. Chang"}], "url": "https://www.semanticscholar.org/paper/c7931f4e9210c05be0685aa44c0cf29f407cc94e", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "5ed7795de01e19a65340b794afd1f6c43741ddad", "title": "Q2Graph: a modelling tool for measurement-based quantum computing", "abstract": "The quantum circuit model is the default for encoding an algorithm intended for a NISQ computer or a quantum computing simulator. A simple graph and through it, a graph state - quantum state physically manifesting an abstract graph structure - is syntactically expressive and tractable. A graph representation is well-suited for algorithms intended for a quantum computing facility founded on measurement-based quantum computing (MBQC) principles. Indeed, the process of creating an algorithm-specific graph can be efficiently realised through classical computing hardware. A graph state is a stabiliser state, which means a graph is a (quantum) intermediate representation at all points of the algorithm-specific graph process. We submit Q2Graph, a software package for designing and testing of simple graphs as algorithms for quantum computing facilities based on MQBC design principles. Q2Graph is a suitable modelling tool for NISQ computing facilities: the user is free to reason about structure or characteristics of its graph-as-algorithm without also having to account for (quantum) errors and their impact upon state.", "year": 2022, "publicationDate": "2022-10-03", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2210.00657"}, "citationCount": 1, "referenceCount": 57, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2210.00657", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2074169350", "name": "Greg Bowen"}, {"authorId": "2939492", "name": "S. Devitt"}], "url": "https://www.semanticscholar.org/paper/5ed7795de01e19a65340b794afd1f6c43741ddad", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "add8cee264deea67f25b1cc518157b43be0e24f5", "title": "Quantum computing overview: discrete vs. continuous variable models", "abstract": "In this Near Intermediate-Scale Quantum era, there are two types of near-term quantum devices available on cloud: superconducting quantum processing units (QPUs) based on the discrete variable model and linear optics (photonics) QPUs based on the continuous variable (CV) model. Quantum computation in the discrete variable model is performed in a finite dimensional quantum state space and the CV model in an infinite dimensional space. In implementing quantum algorithms, the CV model offers more quantum gates that are not available in the discrete variable model. CV-based photonic quantum computers provide additional flexibility of controlling the length of the output vectors of quantum circuits, using different methods of measurement and the notion of cutoff dimension.", "year": 2022, "publicationDate": "2022-06-15", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2206.07246"}, "citationCount": 10, "referenceCount": 40, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2206.07246", "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "34707003", "name": "Sophie Choe"}], "url": "https://www.semanticscholar.org/paper/add8cee264deea67f25b1cc518157b43be0e24f5", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "d3382b11d9e0a991367790dc5412a00d3915b277", "title": "Financial Index Tracking via Quantum Computing with Cardinality Constraints", "abstract": "In this work, we demonstrate how to apply non-linear cardinality constraints, important for real-world asset management, to quantum portfolio optimization. This enables us to tackle non-convex portfolio optimization problems using quantum annealing that would otherwise be challenging for classical algorithms. Being able to use cardinality constraints for portfolio optimization opens the doors to new applications for creating innovative portfolios and exchange-traded-funds (ETFs). We apply the methodology to the practical problem of enhanced index tracking and are able to construct smaller portfolios that significantly outperform the risk profile of the target index whilst retaining high degrees of tracking.", "year": 2022, "publicationDate": "2022-08-24", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2208.11380"}, "citationCount": 9, "referenceCount": 7, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2208.11380", "fieldsOfStudy": ["Computer Science", "Physics", "Economics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Economics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Business", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "2055692445", "name": "Samuel Palmer"}, {"authorId": "48192328", "name": "K. Karagiannis"}, {"authorId": "2160753825", "name": "Adam Florence"}, {"authorId": "2182552780", "name": "Asier Rodriguez"}, {"authorId": "40054109", "name": "R. Orús"}, {"authorId": "32855832", "name": "Harish Naik"}, {"authorId": "102335333", "name": "Samuel Mugel"}], "url": "https://www.semanticscholar.org/paper/d3382b11d9e0a991367790dc5412a00d3915b277", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "8adab85df8ee8d0ce2157b6f52f1649d9a8bbcd7", "title": "Developing a Framework for Sonifying Variational Quantum Algorithms: Implications for Music Composition", "abstract": "This chapter examines the Variational Quantum Harmonizer, a software tool and musical interface that focuses on the problem of sonification of the minimization steps of Variational Quantum Algorithms (VQA), used for simulating properties of quantum systems and optimization problems assisted by quantum hardware. Particularly, it details the sonification of Quadratic Unconstrained Binary Optimization (QUBO) problems using VQA. A flexible design enables its future applications both as a sonification tool for auditory displays in scientific investigation, and as a hybrid quantum-digital musical instrument for artistic endeavours. In turn, sonification can help researchers understand complex systems better and can serve for the training of quantum physics and quantum computing. The VQH structure, including its software implementation, control mechanisms, and sonification mappings are detailed. Moreover, it guides the design of QUBO cost functions in VQH as a music compositional object. The discussion is extended to the implications of applying quantum-assisted simulation in quantum-computer aided composition and live-coding performances. An artistic output is showcased by the piece \\textit{Hexagonal Chambers} (Thomas and Itabora\\'i, 2023).", "year": 2024, "publicationDate": "2024-09-11", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.07104"}, "citationCount": 3, "referenceCount": 46, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2409.07104", "fieldsOfStudy": ["Computer Science", "Engineering", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Art", "source": "s2-fos-model"}], "authors": [{"authorId": "2097423047", "name": "P. Itaboraí"}, {"authorId": "2206043219", "name": "Peter Thomas"}, {"authorId": "2161242162", "name": "Arianna Crippa"}, {"authorId": "2268884964", "name": "Karl Jansen"}, {"authorId": "2248119941", "name": "Tim Schwägerl"}, {"authorId": "2320725277", "name": "María Aguado Yáñez"}], "url": "https://www.semanticscholar.org/paper/8adab85df8ee8d0ce2157b6f52f1649d9a8bbcd7", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "22a3c66d393e334b3a46a2d51d8439927ac73351", "title": "Quantum Algorithms for Optimal Power Flow", "abstract": "This paper explores the use of quantum computing, specifically the use of HHL and VQLS algorithms, to solve optimal power flow problem in electrical grids. We investigate the effectiveness of these quantum algorithms in comparison to classical methods. The simulation results presented here which substantially improve the results in [1] indicate that quantum approaches yield similar solutions and optimal costs compared to classical methods, suggesting the potential use case of quantum computing for power system optimization.", "year": 2024, "publicationDate": "2024-12-09", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2412.06177"}, "citationCount": 3, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics", "Engineering", "Mathematics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2494259", "name": "S. F. Hafshejani"}, {"authorId": "2334529937", "name": "M. Uddin"}, {"authorId": "2263547000", "name": "David Neufeld"}, {"authorId": "2470016", "name": "D. Gaur"}, {"authorId": "2247072", "name": "R. Benkoczi"}], "url": "https://www.semanticscholar.org/paper/22a3c66d393e334b3a46a2d51d8439927ac73351", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "e06d5d67ae91ba8434ef70e7f30c5bf3902fd77c", "title": "Retrodictive Quantum Computing", "abstract": "Quantum models of computation are widely believed to be more powerful than classical ones. Efforts center on proving that, for a given problem, quantum algorithms are more resource efficient than any classical one. All this, however, assumes a standard predictive paradigm of reasoning where, given initial conditions, the future holds the answer. How about bringing information from the future to the present and exploit it to one's advantage? This is a radical new approach for reasoning, so-called Retrodictive Computation, that benefits from the specific form of the computed functions. We demonstrate how to use tools of symbolic computation to realize retrodictive quantum computing at scale and exploit it to efficiently, and classically, solve instances of the quantum Deutsch-Jozsa, Bernstein-Vazirani, Simon, Grover, and Shor's algorithms.", "year": 2022, "publicationDate": "2022-05-12", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2205.06346"}, "citationCount": 0, "referenceCount": 42, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2205.06346", "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "1769166", "name": "J. Carette"}, {"authorId": "2072579167", "name": "G. Ortiz"}, {"authorId": "145919330", "name": "A. Sabry"}], "url": "https://www.semanticscholar.org/paper/e06d5d67ae91ba8434ef70e7f30c5bf3902fd77c", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "bb0747ad2f1f9f781d5916da957117bbc2843b02", "title": "Hybrid Quantum-HPC Solutions for Max-Cut: Bridging Classical and Quantum Algorithms", "abstract": "This research explores the integration of the Quantum Approximate Optimization Algorithm (QAOA) into Hybrid Quantum-HPC systems for solving the Max-Cut problem, comparing its performance with classical algorithms like brute-force search and greedy heuristics. We develop a theoretical model to analyze the time complexity, scalability, and communication overhead in hybrid systems. Using simulations, we evaluate QAOA's performance on small-scale Max-Cut instances, benchmarking its runtime, solution accuracy, and resource utilization. The study also investigates the scalability of QAOA with increasing problem size, offering insights into its potential advantages over classical methods for large-scale combinatorial optimization problems, with implications for future Quantum computing applications in HPC environments.", "year": 2024, "publicationDate": "2024-10-21", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2410.15626"}, "citationCount": 2, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2284886232", "name": "Ishan Patwardhan"}, {"authorId": "2326988227", "name": "Akhil Akkapelli"}], "url": "https://www.semanticscholar.org/paper/bb0747ad2f1f9f781d5916da957117bbc2843b02", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "f3530ce0aa15697f86ded6963a9482f517bc2ded", "title": "Enhancing Quantum Variational Algorithms with Zero Noise Extrapolation via Neural Networks", "abstract": "In the emergent realm of quantum computing, the Variational Quantum Eigensolver (VQE) stands out as a promising algorithm for solving complex quantum problems, especially in the noisy intermediate-scale quantum (NISQ) era. However, the ubiquitous presence of noise in quantum devices often limits the accuracy and reliability of VQE outcomes. This research introduces a novel approach to ameliorate this challenge by utilizing neural networks for zero noise extrapolation (ZNE) in VQE computations. By employing the Qiskit framework, we crafted parameterized quantum circuits using the RY-RZ ansatz and examined their behavior under varying levels of depolarizing noise. Our investigations spanned from determining the expectation values of a Hamiltonian, defined as a tensor product of Z operators, under different noise intensities to extracting the ground state energy. To bridge the observed outcomes under noise with the ideal noise-free scenario, we trained a Feed Forward Neural Network on the error probabilities and their associated expectation values. Remarkably, our model proficiently predicted the VQE outcome under hypothetical noise-free conditions. By juxtaposing the simulation results with real quantum device executions, we unveiled the discrepancies induced by noise and showcased the efficacy of our neural network-based ZNE technique in rectifying them. This integrative approach not only paves the way for enhanced accuracy in VQE computations on NISQ devices but also underlines the immense potential of hybrid quantum-classical paradigms in circumventing the challenges posed by quantum noise. Through this research, we envision a future where quantum algorithms can be reliably executed on noisy devices, bringing us one step closer to realizing the full potential of quantum computing.", "year": 2024, "publicationDate": "2024-03-10", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2403.07025"}, "citationCount": 3, "referenceCount": 25, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2237222278", "name": "Subhasree Bhattacharjee"}, {"authorId": "2290970320", "name": "Soumyadip Sarkar"}, {"authorId": "2237219080", "name": "Kunal Das"}, {"authorId": "2237217692", "name": "Bikramjit Sarkar"}], "url": "https://www.semanticscholar.org/paper/f3530ce0aa15697f86ded6963a9482f517bc2ded", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "66c6e8321b1c90ba564f8cc129ed33c3c2988ea9", "title": "Quantum Approximate Optimization Algorithms for Maxmimum Cut on Low-Girth Graphs", "abstract": "Maximum cut (MaxCut) on graphs is a classic NP-hard problem. In quantum computing, Farhi, Gutmann, and Goldstone proposed the Quantum Approximate Optimization Algorithm (QAOA) for solving the MaxCut problem. Its guarantee on cut fraction (the fraction of edges in the output cut over all edges) was mainly studied for high-girth graphs, i.e., graphs with only long cycles. On the other hand, low-girth graphs are ubiquitous in theoretical computer science, including expander graphs being outstanding examples with wide applications in theory and beyond. In this paper, we apply QAOA to MaxCut on a set of expander graphs proposed by Mohanty and O'Donnell known as additive product graphs. Additionally, we apply multi-angle QAOA (ma-QAOA) to better utilize the graph structure of additive product graphs in ansatz design. In theory, we derive an iterative formula to calculate the expected cut fraction of such graphs. This formula also extends to the quantum MaxCut problem. On the other hand, we conduct numerical experiments to compare between best-known classical local algorithms and QAOA with constant depth. Our results demonstrate that QAOA outperforms the best-known classical algorithms by 0.3% to 5.2% on several additive product graphs, while ma-QAOA further enhances this advantage by an additional 0.6% to 2.5%. In particular, we observe cases that ma-QAOA exhibits superiority over best-known classical algorithms but QAOA does not. Furthermore, we extend our experiments to planar graphs such as tiling grid graphs, where QAOA also demonstrates an advantage.", "year": 2024, "publicationDate": "2024-10-06", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2410.04409"}, "citationCount": 2, "referenceCount": 18, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "2324838746", "name": "Tongyang Li"}, {"authorId": "2324794922", "name": "Yuexin Su"}, {"authorId": "2325199062", "name": "Ziyi Yang"}, {"authorId": "2282530452", "name": "Shengyu Zhang"}], "url": "https://www.semanticscholar.org/paper/66c6e8321b1c90ba564f8cc129ed33c3c2988ea9", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "8eede6d3ee31751d152aa308bf95e205101a1d5c", "title": "The Continuous Logarithm in the Complex Circle for Post-Quantum Cryptographic Algorithms", "abstract": "This paper introduces a novel cryptographic approach based on the continuous logarithm in the complex circle, designed to address the challenges posed by quantum computing. By leveraging its multi-valued and spectral properties, this framework enables the reintroduction of classical algorithms (DH, ECDSA, ElGamal, EC) and elliptic curve variants into the post-quantum landscape. Transitioning from classical or elliptic algebraic structures to the geometric and spectral properties of the complex circle, we propose a robust and adaptable foundation for post-quantum cryptography.", "year": 2024, "publicationDate": "2024-12-24", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2501.10394"}, "citationCount": 1, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "2286571765", "name": "Jaafar Gaber"}], "url": "https://www.semanticscholar.org/paper/8eede6d3ee31751d152aa308bf95e205101a1d5c", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "80734ce6ff67b273bacc778c3cc103e1b72d2f1e", "title": "Quantum Time-Series Learning with Evolutionary Algorithms", "abstract": "Variational quantum circuits have arisen as an important method in quantum computing. A crucial step of it is parameter optimization, which is typically tackled through gradient-descent techniques. We advantageously explore instead the use of evolutionary algorithms for such optimization, specifically for time-series forecasting. We perform a comparison, for diverse instances of real-world data, between gradient-descent parameter optimization and covariant-matrix adaptation evolutionary strategy. We observe that gradient descent becomes permanently trapped in local minima that have been avoided by evolutionary algorithms in all tested datasets, reaching up to a six-fold decrease in prediction error. Finally, the combined use of evolutionary and gradient-based techniques is explored, aiming at retaining advantages of both. The results are particularly applicable in scenarios sensitive to gains in accuracy.", "year": 2024, "publicationDate": "2024-12-23", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2412.17580"}, "citationCount": 0, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2135781502", "name": "Vignesh Anantharamakrishnan"}, {"authorId": "145162511", "name": "M. M. Taddei"}], "url": "https://www.semanticscholar.org/paper/80734ce6ff67b273bacc778c3cc103e1b72d2f1e", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "0d71800165c99ef46ff38faa1dfcd9c53b9da1ce", "title": "Efficient charge-preserving excited state preparation with variational quantum algorithms", "abstract": "Determining the spectrum and wave functions of excited states of a system is crucial in quantum physics and chemistry. Low-depth quantum algorithms, such as the Variational Quantum Eigensolver (VQE) and its variants, can be used to determine the ground-state energy. However, current approaches to computing excited states require numerous controlled unitaries, making the application of the original Variational Quantum Deflation (VQD) algorithm to problems in chemistry or physics suboptimal. In this study, we introduce a charge-preserving VQD (CPVQD) algorithm, designed to incorporate symmetry and the corresponding conserved charge into the VQD framework. This results in dimension reduction, significantly enhancing the efficiency of excited-state computations. We present benchmark results with GPU-accelerated simulations using systems up to 24 qubits, showcasing applications in high-energy physics, nuclear physics, and quantum chemistry. This work is performed on NERSC's Perlmutter system using NVIDIA's open-source platform for accelerated quantum supercomputing - CUDA-Q.", "year": 2024, "publicationDate": "2024-10-18", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2410.14357"}, "citationCount": 5, "referenceCount": 61, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Chemistry", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2326841690", "name": "Zohim Chandani"}, {"authorId": "2270216687", "name": "Kazuki Ikeda"}, {"authorId": "2390396747", "name": "Zhong-Bo Kang"}, {"authorId": "2249449289", "name": "D. Kharzeev"}, {"authorId": "2241631314", "name": "Alex McCaskey"}, {"authorId": "2283849255", "name": "Andrea Palermo"}, {"authorId": "2262063438", "name": "C. Ramakrishnan"}, {"authorId": "2291989883", "name": "P. Rao"}, {"authorId": "1666329863", "name": "Ranjani G. Sundaram"}, {"authorId": "2295796365", "name": "Kwangmin Yu"}], "url": "https://www.semanticscholar.org/paper/0d71800165c99ef46ff38faa1dfcd9c53b9da1ce", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "0373f0a9936dd29fe67900d50d5bfe8f620a9a17", "title": "Denoising Gradient Descent in Variational Quantum Algorithms", "abstract": "In this article we introduce an algorithm for mitigating the adverse effects of noise on gradient descent in variational quantum algorithms. This is accomplished by computing a {\\emph{regularized}} local classical approximation to the objective function at every gradient descent step. The computational overhead of our algorithm is entirely classical, i.e., the number of circuit evaluations is exactly the same as when carrying out gradient descent using the parameter-shift rules. We empirically demonstrate the advantages offered by our algorithm on randomized parametrized quantum circuits.", "year": 2024, "publicationDate": "2024-03-06", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2403.03826"}, "citationCount": 2, "referenceCount": 26, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2228838152", "name": "Lars Simon"}, {"authorId": "2256997940", "name": "Holger Eble"}, {"authorId": "103668125", "name": "Hagen-Henrik Kowalski"}, {"authorId": "2921643", "name": "Manuel Radons"}], "url": "https://www.semanticscholar.org/paper/0373f0a9936dd29fe67900d50d5bfe8f620a9a17", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "faa94752b8705f8c85d38e23283a240b69192d90", "title": "Kernel Descent - a Novel Optimizer for Variational Quantum Algorithms", "abstract": null, "year": 2024, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2409.10257"}, "citationCount": 0, "referenceCount": 27, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2228838152", "name": "Lars Simon"}, {"authorId": "2256997940", "name": "Holger Eble"}, {"authorId": "2921643", "name": "Manuel Radons"}], "url": "https://www.semanticscholar.org/paper/faa94752b8705f8c85d38e23283a240b69192d90", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "07301bb451c1164e0d7e3674437391fc5d95953f", "title": "Lecture Notes on Quantum Algorithms for Scientific Computation", "abstract": "This is a set of lecture notes used in a graduate topic class in applied mathematics called ``Quantum Algorithms for Scientific Computation'' at the Department of Mathematics, UC Berkeley during the fall semester of 2021. These lecture notes focus only on quantum algorithms closely related to scientific computation, and in particular, matrix computation. The main purpose of the lecture notes is to introduce quantum phase estimation (QPE) and ``post-QPE'' methods such as block encoding, quantum signal processing, and quantum singular value transformation, and to demonstrate their applications in solving eigenvalue problems, linear systems of equations, and differential equations. The intended audience is the broad computational science and engineering (CSE) community interested in using fault-tolerant quantum computers to solve challenging scientific computing problems.", "year": 2022, "publicationDate": "2022-01-20", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2201.08309"}, "citationCount": 102, "referenceCount": 0, "influentialCitationCount": 22, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics", "Mathematics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "2149047090", "name": "Lin Lin"}], "url": "https://www.semanticscholar.org/paper/07301bb451c1164e0d7e3674437391fc5d95953f", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "62b22b95e49996f00a6ca2f67298583e2a634e44", "title": "The Conquest of Quantum Genetic Algorithms: The Adventure to Cross the Valley of Death", "abstract": "In recent years, the emergence of the first quantum computers at a time when AI is undergoing a fruitful era has led many AI researchers to be tempted into adapting their algorithms to run on a quantum computer. However, in many cases the initial enthusiasm has ended in frustration, since the features and principles underlying quantum computing are very different from traditional computers. In this paper, we present a discussion of the difficulties arising when designing a quantum version of an evolutionary algorithm based on Darwin's evolutionary mechanism, the so-called genetic algorithms. The paper includes the code in both Python and QISKIT of the quantum version of one of these evolutionary algorithms allowing the reader to experience the setbacks arising when translating a classical algorithm to its quantum version. The algorithm studied in this paper, termed RQGA (Reduced Quantum Genetic Algorithm), has been chosen as an example that clearly shows these difficulties, which are common to other AI algorithms.", "year": 2023, "publicationDate": "2023-12-10", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2401.08631"}, "citationCount": 3, "referenceCount": 33, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2265760699", "name": "Rafael Lahoz-Beltra"}], "url": "https://www.semanticscholar.org/paper/62b22b95e49996f00a6ca2f67298583e2a634e44", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "27f3486918b319bcad7f08387c6f423bcb5ba749", "title": "Indirect Quantum Approximate Optimization Algorithms: application to the TSP", "abstract": "We propose an Indirect Quantum Approximate Optimization Algorithm (referred to as IQAOA) where the Quantum Alternating Operator Ansatz takes into consideration a general parameterized family of unitary operators to efficiently model the Hamiltonian describing the set of string vectors. This algorithm creates an efficient alternative to QAOA, where: 1) a Quantum parametrized circuit executed on a quantum machine models the set of string vectors; 2) a Classical meta-optimization loop executed on a classical machine; 3) an estimation of the average cost of each string vector computing, using a well know algorithm coming from the OR community that is problem dependent. The indirect encoding defined by dimensional string vector is mapped into a solution by an efficient coding/decoding mechanism. The main advantage is to obtain a quantum circuit with a strongly limited number of gates that could be executed on the noisy current quantum machines. The numerical experiments achieved with IQAOA permits to solve 8-customer instances TSP using the IBM simulator which are to the best of our knowledge the largest TSP ever solved using a QAOA based approach.", "year": 2023, "publicationDate": "2023-11-06", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2311.03294"}, "citationCount": 11, "referenceCount": 20, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "3254622", "name": "E. Bourreau"}, {"authorId": "150110568", "name": "G. Fleury"}, {"authorId": "1793517", "name": "P. Lacomme"}], "url": "https://www.semanticscholar.org/paper/27f3486918b319bcad7f08387c6f423bcb5ba749", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "ad64c1ebb32fa63c3170935e361a3c61a33886dc", "title": "Influences of Fourier Completely Bounded Polynomials and Classical Simulation of Quantum Algorithms", "abstract": "We give a new presentation of the main result of Arunachalam, Bri\\\"et and Palazuelos (SICOMP'19) and show that quantum query algorithms are characterized by a new class of polynomials which we call Fourier completely bounded polynomials. We conjecture that all such polynomials have an influential variable. This conjecture is weaker than the famous Aaronson-Ambainis (AA) conjecture (Theory of Computing'14), but has the same implications for classical simulation of quantum query algorithms. We prove a new case of the AA conjecture by showing that it holds for homogeneous Fourier completely bounded polynomials. This implies that if the output of $d$-query quantum algorithm is a homogeneous polynomial $p$ of degree $2d$, then it has a variable with influence at least $Var[p]^2$. In addition, we give an alternative proof of the results of Bansal, Sinha and de Wolf (CCC'22 and QIP'23) showing that block-multilinear completely bounded polynomials have influential variables. Our proof is simpler, obtains better constants and does not use randomness.", "year": 2023, "publicationDate": "2023-04-13", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2304.06713"}, "citationCount": 4, "referenceCount": 34, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2304.06713", "fieldsOfStudy": ["Physics", "Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "2214314799", "name": "Francisco Escudero Guti'errez"}], "url": "https://www.semanticscholar.org/paper/ad64c1ebb32fa63c3170935e361a3c61a33886dc", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "81745e3961d71a7566b608adfa2840eb0caad4d7", "title": "Simulating Noisy Quantum Circuits for Cryptographic Algorithms", "abstract": "The emergence of noisy intermediate-scale quantum (NISQ) computers has important consequences for cryptographic algorithms. It is theoretically well-established that key algorithms used in cybersecurity are vulnerable to quantum computers due to the fact that theoretical security guarantees, designed based on algorithmic complexity for classical computers, are not sufficient for quantum circuits. Many different quantum algorithms have been developed, which have potentially broad applications on future computing systems. However, this potential depends on the continued maturation of quantum hardware, which remains an area of active research and development. Theoretical limits provide an upper bound on the performance for algorithms. In practice, threats to encryption can only be accurately be assessed in the context of the rapidly evolving hardware and software landscape. Software co-design refers to the concurrent design of software and hardware as a way to understand the limitations of current capabilities and develop effective strategies to advance the state of the art. Since the capabilities for classical computation currently exceed quantum capabilities, quantum emulation techniques can play an important role in the co-design process. In this paper, we describe how the {\\em cuQuantum} environment can support quantum algorithm co-design activities using widely-available commodity hardware. We describe how emulation techniques can be used to assess the impact of noise on algorithms of interest, and identify limitations associated with current hardware. We present our analysis in the context of areas of priority for cybersecurity and cryptography in particular since these algorithms are extraordinarily consequential for securing information in the digital world.", "year": 2023, "publicationDate": "2023-06-03", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2306.02111"}, "citationCount": 0, "referenceCount": 30, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2306.02111", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2219549264", "name": "Sahay Harshvardhan"}, {"authorId": "29838327", "name": "Sanil Jain"}, {"authorId": "32853145", "name": "J. McClure"}, {"authorId": "2219551828", "name": "Caleb McIrvin"}, {"authorId": "2122013066", "name": "Ngoc Quy Tran"}], "url": "https://www.semanticscholar.org/paper/81745e3961d71a7566b608adfa2840eb0caad4d7", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "ff4e55dbbf09f3ba0d76b699d3d520ae0bdd26b9", "title": "An LLVM-based C++ Compiler Toolchain for Variational Hybrid Quantum-Classical Algorithms and Quantum Accelerators", "abstract": "Variational algorithms are a representative class of quantum computing workloads that combine quantum and classical computing. This paper presents an LLVM-based C++ compiler toolchain to efficiently execute variational hybrid quantum-classical algorithms on a computational system in which the quantum device acts as an accelerator. We introduce a set of extensions to the C++ language for programming these algorithms. We define a novel Executable and Linking Format (ELF) for Quantum and create a quantum device compiler component in the LLVM framework to compile the quantum part of the C++ source and reuse the host compiler in the LLVM framework to compile the classical computing part of the C++ source. A variational algorithm runs a quantum circuit repeatedly, each time with different gate parameters. We add to the quantum runtime the capability to execute dynamically a quantum circuit with different parameters. Thus, programmers can call quantum routines the same way as classical routines. With these capabilities, a variational hybrid quantum-classical algorithm can be specified in a single-source code and only needs to be compiled once for all iterations. The single compilation significantly reduces the execution latency of variational algorithms. We evaluate the framework's performance by running quantum circuits that prepare Thermofield Double (TFD) states, a quantum-classical variational algorithm.", "year": 2022, "publicationDate": "2022-02-22", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2202.11142"}, "citationCount": 19, "referenceCount": 37, "influentialCitationCount": 2, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2155890956", "name": "Pradnya Khalate"}, {"authorId": "12177285", "name": "Xin-Chuan Wu"}, {"authorId": "31662552", "name": "S. Premaratne"}, {"authorId": "90353360", "name": "J. Hogaboam"}, {"authorId": "144058138", "name": "Adam Holmes"}, {"authorId": "103188288", "name": "A. Schmitz"}, {"authorId": "3180028", "name": "G. Guerreschi"}, {"authorId": "121488860", "name": "X. Zou"}, {"authorId": "2080128828", "name": "A. Matsuura"}], "url": "https://www.semanticscholar.org/paper/ff4e55dbbf09f3ba0d76b699d3d520ae0bdd26b9", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "d689cad96a9de946094495ce53b2872fe8c39fe6", "title": "Robust Quantum Controllers: Quantum Information - Thermodynamic Hidden Force Control in Intelligent Robotics based on Quantum Soft Computing", "abstract": "A generalized strategy for the design of intelligent robust control systems based on quantum / soft computing technologies is described. The reliability of hybrid intelligent controllers increase by providing the ability to self-organize of imperfect knowledge bases. The main attention is paid to increasing the level of robustness of intelligent control systems in unpredictable control situations with the demonstration by illustrative examples. A SW&HW platform and support tools for a supercomputer accelerator for modeling quantum algorithms on a classical computer are described.", "year": 2023, "publicationDate": "2023-05-18", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2305.11254"}, "citationCount": 0, "referenceCount": 42, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2305.11254", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "34244669", "name": "S. Ulyanov"}, {"authorId": "2342815", "name": "V. Ulyanov"}, {"authorId": "2217944375", "name": "Takakhide Hagiwara"}], "url": "https://www.semanticscholar.org/paper/d689cad96a9de946094495ce53b2872fe8c39fe6", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "476ce59dff011579589a2b02dd4de930194d10b4", "title": "How to Build a Quantum Supercomputer: Scaling from Hundreds to Millions of Qubits", "abstract": "In the span of four decades, quantum computation has evolved from an intellectual curiosity to a potentially realizable technology. Today, small-scale demonstrations have become possible for quantum algorithmic primitives on hundreds of physical qubits. Nevertheless, there are significant outstanding challenges in quantum hardware, fabrication, software architecture, and algorithms on the path towards a full-stack scalable quantum computing technology. Here, we provide a comprehensive review of these scaling challenges. We show how to facilitate scaling by adopting existing semiconductor technology to build much higher-quality qubits, employing systems engineering approaches, and performing distributed heterogeneous quantum-classical computing. We provide a detailed resource and sensitivity analysis for quantum applications on surface-code error-corrected quantum computers given current, target, and desired hardware specifications based on superconducting qubits, accounting for a realistic distribution of errors. We provide comprehensive resource estimates for several utility-scale applications including quantum chemistry calculations, catalyst design, NMR spectroscopy, and Fermi-Hubbard simulation. We show that orders of magnitude enhancement in performance could be obtained by a combination of hardware improvements and tight quantum-HPC integration. Furthermore, we introduce high-performance architectures for quantum-probabilistic computing with custom-designed accelerators to tackle today's industry-scale classical optimization, machine learning, and quantum simulation tasks in a cost-effective manner.", "year": 2024, "publicationDate": "2024-11-15", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2411.10406"}, "citationCount": 102, "referenceCount": 0, "influentialCitationCount": 8, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2309175767", "name": "Masoud Mohseni"}, {"authorId": "2303464710", "name": "Artur Scherer"}, {"authorId": "2262203037", "name": "K. Johnson"}, {"authorId": "8804999", "name": "O. Wertheim"}, {"authorId": "2331172431", "name": "M. Otten"}, {"authorId": "31047446", "name": "Navid Anjum Aadit"}, {"authorId": "1854551", "name": "Kirk M. Bresniker"}, {"authorId": "3451581", "name": "Kerem Y Çamsarı"}, {"authorId": "2298156130", "name": "Barbara Chapman"}, {"authorId": "2113355217", "name": "Soumitra Chatterjee"}, {"authorId": "2042446681", "name": "Gebremedhin A. Dagnew"}, {"authorId": "2268960841", "name": "Aniello Esposito"}, {"authorId": "2265583256", "name": "F. Fahim"}, {"authorId": "2249995934", "name": "M. Fiorentino"}, {"authorId": "2329562089", "name": "Abdullah Khalid"}, {"authorId": "2329943448", "name": "Xiangzhou Kong"}, {"authorId": "103330749", "name": "B. Kulchytskyy"}, {"authorId": "2260818581", "name": "Ruoyu Li"}, {"authorId": "113627833", "name": "P. A. Lott"}, {"authorId": "2257251123", "name": "Igor L. Markov"}, {"authorId": "2238227163", "name": "R. McDermott"}, {"authorId": "2273562647", "name": "Giacomo Pedretti"}, {"authorId": "27654379", "name": "Archit Gajjar"}, {"authorId": "2303661625", "name": "Allyson Silva"}, {"authorId": "100929030", "name": "J. Sorebo"}, {"authorId": "2301598892", "name": "Panagiotis Spentzouris"}, {"authorId": "2331172474", "name": "Ziv Steiner"}, {"authorId": "12199588", "name": "B. Torosov"}, {"authorId": "2294566348", "name": "Davide Venturelli"}, {"authorId": "2331172682", "name": "R. J. Visser"}, {"authorId": "2303466722", "name": "Zak Webb"}, {"authorId": "2331172989", "name": "Xin Zhan"}, {"authorId": "2266390298", "name": "Yonatan Cohen"}, {"authorId": "2789901", "name": "Pooya Ronagh"}, {"authorId": "145106485", "name": "A. Ho"}, {"authorId": "2281743410", "name": "R. Beausoleil"}, {"authorId": "3264596", "name": "J. Martinis"}], "url": "https://www.semanticscholar.org/paper/476ce59dff011579589a2b02dd4de930194d10b4", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "6ed0c14f7ccd283fedd0de3a1c393a7c81cf034c", "title": "Quantum Algorithms for solving Hard Constrained Optimisation Problems", "abstract": "The thesis deals with Quantum Algorithms for solving Hard Constrained Optimization Problems. It shows how quantum computers can solve difficult everyday problems such as finding the best schedule for social workers or the path of a robot picking and batching in a warehouse. The path to the solution has led to the definition of a new artificial intelligence paradigm with quantum computing, quantum Case-Based Reasoning (qCBR) and to a proof of concept to integrate the capacity of quantum computing within mobile robotics using a Raspberry Pi 4 as a processor (qRobot), capable of operating with leading technology players such as IBMQ, Amazon Braket (D-Wave) and Pennylane. To improve the execution time of variational algorithms in this NISQ era and the next, we have proposed EVA: a quantum Exponential Value Approximation algorithm that speeds up the VQE, and that is, to date, the flagship of the quantum computation. To improve the execution time of variational algorithms in this NISQ era and the next, we have proposed EVA: a quantum Exponential Value Approximation algorithm that speeds up the VQE, and that is, to date, the flagship of the quantum computation.", "year": 2022, "publicationDate": "2022-02-26", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2202.13125"}, "citationCount": 11, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2061745884", "name": "Parfait Atchade-Adelomou"}], "url": "https://www.semanticscholar.org/paper/6ed0c14f7ccd283fedd0de3a1c393a7c81cf034c", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "685afadbce1f4facea2c296f6575c59bfff8cf2b", "title": "Basic Quantum Algorithms", "abstract": "Quantum computing is evolving so rapidly that it forces us to revisit, rewrite, and update the foundations of the theory. \\emph{Basic Quantum Algorithms} revisits the earliest quantum algorithms. The journey began in 1985 with Deutsch attempting to evaluate a function at two domain points simultaneously. Then, in 1992, Deutsch and Jozsa created a quantum algorithm that determines whether a Boolean function is constant or balanced. The following year, Bernstein and Vazirani realized that essentially the same algorithm could be used to identify a specific Boolean function within a set of linear Boolean functions. In 1994, Simon introduced a novel quantum algorithm that determines whether a function is one-to-one or two-to-one exponentially faster than any classical algorithm for the same problem. That same year, Shor developed two groundbreaking quantum algorithms for integer factoring and calculating discrete logarithms, posing a threat to widely used cryptographic methods. In 1995, Kitaev proposed an alternative formulation based on phase estimation that proved valuable in numerous applications. The following year, Grover devised a quantum search algorithm that is quadratically faster than its classical counterpart. More than a decade later, Harrow, Hassidim, and Lloyd proposed a quantum algorithm for solving systems of linear equations, now known as the HHL algorithm. With an emphasis on the circuit model, this work provides a detailed description of all these remarkable algorithms.", "year": 2022, "publicationDate": "2022-01-25", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2201.10574"}, "citationCount": 3, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "145627848", "name": "R. Portugal"}], "url": "https://www.semanticscholar.org/paper/685afadbce1f4facea2c296f6575c59bfff8cf2b", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "e3ba9a5db77c6b7a039207552340f15148ed8001", "title": "Post-Quantum Cryptography for Internet of Things: A Survey on Performance and Optimization", "abstract": "Due to recent development in quantum computing, the invention of a large quantum computer is no longer a distant future. Quantum computing severely threatens modern cryptography, as the hard mathematical problems beneath classic public-key cryptosystems can be solved easily by a sufficiently large quantum computer. As such, researchers have proposed PQC based on problems that even quantum computers cannot efficiently solve. Generally, post-quantum encryption and signatures can be hard to compute. This could potentially be a problem for IoT, which usually consist lightweight devices with limited computational power. In this paper, we survey existing literature on the performance for PQC in resource-constrained devices to understand the severeness of this problem. We also review recent proposals to optimize PQC algorithms for resource-constrained devices. Overall, we find that whilst PQC may be feasible for reasonably lightweight IoT, proposals for their optimization seem to lack standardization. As such, we suggest future research to seek coordination, in order to ensure an efficient and safe migration toward IoT for the post-quantum era.", "year": 2024, "publicationDate": "2024-01-31", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2401.17538"}, "citationCount": 83, "referenceCount": 74, "influentialCitationCount": 8, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2282117944", "name": "Tao Liu"}, {"authorId": "2211123747", "name": "G. Ramachandran"}, {"authorId": "2273364573", "name": "Raja Jurdak"}], "url": "https://www.semanticscholar.org/paper/e3ba9a5db77c6b7a039207552340f15148ed8001", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "ed57f4dde9b0a173bd7a39b2ad4777c27d7afa47", "title": "From Quantum Graph Computing to Quantum Graph Learning: A Survey", "abstract": "Quantum computing (QC) is a new computational paradigm whose foundations relate to quantum physics. Notable progress has been made, driving the birth of a series of quantum-based algorithms that take advantage of quantum computational power. In this paper, we provide a targeted survey of the development of QC for graph-related tasks. We first elaborate the correlations between quantum mechanics and graph theory to show that quantum computers are able to generate useful solutions that can not be produced by classical systems efficiently for some problems related to graphs. For its practicability and wide-applicability, we give a brief review of typical graph learning techniques designed for various tasks. Inspired by these powerful methods, we note that advanced quantum algorithms have been proposed for characterizing the graph structures. We give a snapshot of quantum graph learning where expectations serve as a catalyst for subsequent research. We further discuss the challenges of using quantum algorithms in graph learning, and future directions towards more flexible and versatile quantum graph learning solvers.", "year": 2022, "publicationDate": "2022-02-19", "publicationTypes": ["JournalArticle", "Review"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2202.09506"}, "citationCount": 12, "referenceCount": 82, "influentialCitationCount": 1, "isOpenAccess": false, "openAccessPdfUrl": null, "fieldsOfStudy": ["Physics", "Computer Science"], "s2FieldsOfStudy": [{"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}, {"category": "Mathematics", "source": "s2-fos-model"}], "authors": [{"authorId": "103603255", "name": "Yehui Tang"}, {"authorId": "3063894", "name": "Junchi Yan"}, {"authorId": "2155487197", "name": "H. Edwin"}], "url": "https://www.semanticscholar.org/paper/ed57f4dde9b0a173bd7a39b2ad4777c27d7afa47", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "0223db3a9042664f4529dc235ad9f7a662dc15af", "title": "Discussion of Quantum Consensus Algorithms", "abstract": "Leader election is a crucial process in many areas such as cloud computing, distributed systems, task orchestration, and blockchain. Oftentimes, in a distributed system, the network needs to choose a leader, which would be responsible for synchronization between different processors, data storage, information distribution, and more.", "year": 2022, "publicationDate": "2022-06-09", "publicationTypes": ["JournalArticle"], "venue": "arXiv.org", "journal": {"name": "ArXiv", "volume": "abs/2206.04710"}, "citationCount": 2, "referenceCount": 5, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2206.04710", "fieldsOfStudy": ["Computer Science", "Physics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Physics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Physics", "source": "s2-fos-model"}], "authors": [{"authorId": "2108025805", "name": "Lifu Zhang"}, {"authorId": "2051458279", "name": "Samuel Fulton"}], "url": "https://www.semanticscholar.org/paper/0223db3a9042664f4529dc235ad9f7a662dc15af", "_run_id": "d07cF2F3y6kR2Ylhm", "_dataset_id": "fNaZIeq4T49AjwWQf"}
{"paperId": "2368d84435085af4cb680bcacf68a8c2fce721dc", "title": "The Safety Filter: A Unified View of Safety-Critical Control in Autonomous Systems", "abstract": "Recent years have seen significant progress in the realm of robot autonomy, accompanied by the expanding reach of robotic technologies. However, the emergence of new deployment domains brings unprecedented challenges in ensuring safe operation of these systems, which remains as crucial as ever. While traditional model-based safe control methods struggle with generalizability and scalability, emerging data-driven approaches tend to lack well-understood guarantees, which can result in unpredictable catastrophic failures. Successful deployment of the next generation of autonomous robots will require integrating the strengths of both paradigms. This article provides a review of safety filter approaches, highlighting important connections between existing techniques and proposing a unified technical framework to understand, compare, and combine them. The new unified view exposes a shared modular structure across a range of seemingly disparate safety filter classes and naturally suggests directions for future progress toward more scalable synthesis, robust monitoring, and efficient intervention. Expected final online publication date for the Annual Review of Control, Robotics, and Autonomous Systems, Volume 7 is May 2024. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.", "year": 2023, "publicationDate": "2023-09-11", "publicationTypes": ["JournalArticle", "Review"], "venue": "Annu. Rev. Control. Robotics Auton. Syst.", "journal": {"name": "Annu. Rev. Control. Robotics Auton. Syst.", "volume": "7"}, "citationCount": 197, "referenceCount": 120, "influentialCitationCount": 17, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2309.05837", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2273954745", "name": "Kai-Chieh Hsu"}, {"authorId": "2284640607", "name": "Haimin Hu"}, {"authorId": "1843342", "name": "J. Fisac"}], "url": "https://www.semanticscholar.org/paper/2368d84435085af4cb680bcacf68a8c2fce721dc", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "bf7281d3d199941a187a6510f9dbe2e81aac71c1", "title": "Adversarial AI Testcases for Maritime Autonomous Systems", "abstract": "Contemporary maritime operations such as shipping are a vital component constituting global trade and defence. The evolution towards maritime autonomous systems, often providing significant benefits (e.g., cost, physical safety), requires the utilisation of artificial intelligence (AI) to automate the functions of a conventional crew. However, unsecured AI systems can be plagued with vulnerabilities naturally inherent within complex AI models. The adversarial AI threat, primarily only evaluated in a laboratory environment, increases the likelihood of strategic adversarial exploitation and attacks on mission-critical AI, including maritime autonomous systems. This work evaluates AI threats to maritime autonomous systems in situ. The results show that multiple attacks can be used against real-world maritime autonomous systems with a range of lethality. However, the effects of AI attacks vary in a dynamic and complex environment from that proposed in lower entropy laboratory environments. We propose a set of adversarial test examples and demonstrate their use, specifically in the marine environment. The results of this paper highlight security risks and deliver a set of principles to mitigate threats to AI, throughout the AI lifecycle, in an evolving threat landscape.", "year": 2023, "publicationDate": "2023-04-25", "publicationTypes": ["JournalArticle"], "venue": "AI Computer Science and Robotics Technology", "journal": {"name": "AI, Computer Science and Robotics Technology"}, "citationCount": 33, "referenceCount": 89, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://api.intechopen.com/article/pdf-download/189", "fieldsOfStudy": [], "s2FieldsOfStudy": [{"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1753628641", "name": "Mathew J. Walter"}, {"authorId": "2061123061", "name": "Aaron Barrett"}, {"authorId": "2176870442", "name": "David Walker"}, {"authorId": "2951920", "name": "Kimberly Tam"}], "url": "https://www.semanticscholar.org/paper/bf7281d3d199941a187a6510f9dbe2e81aac71c1", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "08299cd7a55a544332f3815df2fe56ef9e7136d7", "title": "Scalable Learning of Safety Guarantees for Autonomous Systems using Hamilton-Jacobi Reachability", "abstract": "Autonomous systems like aircraft and assistive robots often operate in scenarios where guaranteeing safety is critical. Methods like Hamilton-Jacobi reachability can provide guaranteed safe sets and controllers for such systems. However, often these same scenarios have unknown or uncertain environments, system dynamics, or predictions of other agents. As the system is operating, it may learn new knowledge about these uncertainties and should therefore update its safety analysis accordingly. However, work to learn and update safety analysis is limited to small systems of about two dimensions due to the computational complexity of the analysis. In this paper we synthesize several techniques to speed up computation: decomposition, warm-starting, and adaptive grids. Using this new framework we can update safe sets by one or more orders of magnitude faster than prior work, making this technique practical for many realistic systems. We demonstrate our results on simulated 2D and 10D near-hover quadcopters operating in a windy environment.", "year": 2021, "publicationDate": "2021-01-15", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2021 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "5914-5920"}, "citationCount": 50, "referenceCount": 36, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2101.05916", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "40022924", "name": "Sylvia L. Herbert"}, {"authorId": "2149218929", "name": "Jason J. Choi"}, {"authorId": "2046989060", "name": "Suvansh Qazi"}, {"authorId": "31856058", "name": "Marsalis T. Gibson"}, {"authorId": "144116765", "name": "K. Sreenath"}, {"authorId": "1693894", "name": "C. Tomlin"}], "url": "https://www.semanticscholar.org/paper/08299cd7a55a544332f3815df2fe56ef9e7136d7", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "e3ea899d75cab6bd8297455216fa5a57a6983dfd", "title": "A Review of Verification and Validation for Space Autonomous Systems", "abstract": "The deployment of hardware (e.g., robots, satellites, etc.) to space is a costly and complex endeavor. It is of extreme importance that on-board systems are verified and validated through a variety of verification and validation techniques, especially in the case of autonomous systems. In this paper, we discuss a number of approaches from the literature that are relevant or directly applied to the verification and validation of systems in space, with an emphasis on autonomy. Despite advances in individual verification and validation techniques, there is still a lack of approaches that aim to combine different forms of verification in order to obtain system-wide verification of modular autonomous systems. This systematic review of the literature includes the current advances in the latest approaches using formal methods for static verification (model checking and theorem proving) and runtime verification, the progress achieved so far in the verification of machine learning, an overview of the landscape in software testing, and the importance of performing compositional verification in modular systems. In particular, we focus on reporting the use of these techniques for the verification and validation of systems in space with an emphasis on autonomy, as well as more general techniques (such as in the aeronautical domain) that have been shown to have potential value in the verification and validation of autonomous systems in space.", "year": 2021, "publicationDate": "2021-06-18", "publicationTypes": ["Review"], "venue": "Current Robotics Reports", "journal": {"name": "Current Robotics Reports", "pages": "273 - 283", "volume": "2"}, "citationCount": 26, "referenceCount": 90, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s43154-021-00058-1.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "145080202", "name": "R. C. Cardoso"}, {"authorId": "6161353", "name": "G. Kourtis"}, {"authorId": "2129382244", "name": "L. Dennis"}, {"authorId": "4474343", "name": "C. Dixon"}, {"authorId": "20296883", "name": "M. Farrell"}, {"authorId": "1399456249", "name": "M. Fisher"}, {"authorId": "35022905", "name": "M. Webster"}], "url": "https://www.semanticscholar.org/paper/e3ea899d75cab6bd8297455216fa5a57a6983dfd", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "a9e55f29217317b7aeea62885b4af5e43bac1f05", "title": "Reliability and Safety of Autonomous Systems Based on Semantic Modelling for Self-Certification", "abstract": "A novel modelling paradigm for online diagnostics and prognostics for autonomous systems is presented. A model for the autonomous system being diagnosed is designed using a logic-based formalism. The model supports the run-time ability to verify that the autonomous system is safe and reliable for operation within a dynamic environment. The paradigm is based on the philosophy that there are different types of semantic relationships between the states of different parts of the system. A finite state automaton is devised for each sensed component and some of the non-sensed components. To capture the interdependencies of components within such a complex robotic platform, automatons were related to each other by semantic relationships. Modality was utilised by the formalism to abstract the relationships and to add measures for the possibility and uncertainty of the relationships. The complexity of the model was analysed to evaluate its scalability and applicability to other systems. The results demonstrate that the complexity is not linear and a computational time of 10 ms was required to achieve run-time diagnostics for 2200 KB of knowledge for complex system interdependences. The ability to detect and mitigate hardware related failures was demonstrated within a confined space autonomous operation. Our findings provide evidence of the applicability of our approach for the significant challenge of run-time safety compliance and reliability in autonomous systems.", "year": 2021, "publicationDate": "2021-01-03", "publicationTypes": ["JournalArticle"], "venue": "Robotics", "journal": {"name": "Robotics", "pages": "10", "volume": "10"}, "citationCount": 24, "referenceCount": 63, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2218-6581/10/1/10/pdf?version=1609919580", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "144707346", "name": "O. Zaki"}, {"authorId": "31838690", "name": "M. Dunnigan"}, {"authorId": "1718021", "name": "V. Robu"}, {"authorId": "143836960", "name": "D. Flynn"}], "url": "https://www.semanticscholar.org/paper/a9e55f29217317b7aeea62885b4af5e43bac1f05", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "5b84e022b6286bf72a206b9df9f94e9592244917", "title": "Meaningful Human Control over Autonomous Systems: A Philosophical Account", "abstract": "Debates on lethal autonomous weapon systems have proliferated in the past 5 years. Ethical concerns have been voiced about a possible raise in the number of wrongs and crimes in military operations and about the creation of a “responsibility gap” for harms caused by these systems. To address these concerns, the principle of “meaningful human control” has been introduced in the legal–political debate; according to this principle, humans not computers and their algorithms should ultimately remain in control of, and thus morally responsible for, relevant decisions about (lethal) military operations. However, policy-makers and technical designers lack a detailed theory of what “meaningful human control” exactly means. In this paper, we lay the foundation of a philosophical account of meaningful human control, based on the concept of “guidance control” as elaborated in the philosophical debate on free will and moral responsibility. Following the ideals of “Responsible Innovation” and “Value-sensitive Design,” our account of meaningful human control is cast in the form of design requirements. We identify two general necessary conditions to be satisfied for an autonomous system to remain under meaningful human control: first, a “tracking” condition, according to which the system should be able to respond to both the relevant moral reasons of the humans designing and deploying the system and the relevant facts in the environment in which the system operates; second, a “tracing” condition, according to which the system should be designed in such a way as to grant the possibility to always trace back the outcome of its operations to at least one human along the chain of design and operation. As we think that meaningful human control can be one of the central notions in ethics of robotics and AI, in the last part of the paper, we start exploring the implications of our account for the design and use of non-military autonomous systems, for instance, self-driving cars.", "year": 2018, "publicationDate": "2018-02-28", "publicationTypes": ["JournalArticle"], "venue": "Frontiers in Robotics and AI", "journal": {"name": "Frontiers in Robotics and AI", "volume": "5"}, "citationCount": 444, "referenceCount": 95, "influentialCitationCount": 33, "isOpenAccess": true, "openAccessPdfUrl": "https://www.frontiersin.org/articles/10.3389/frobt.2018.00015/pdf", "fieldsOfStudy": ["Computer Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Philosophy", "source": "s2-fos-model"}, {"category": "Political Science", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "8623431", "name": "F. S. D. Sio"}, {"authorId": "7485612", "name": "J. Hoven"}], "url": "https://www.semanticscholar.org/paper/5b84e022b6286bf72a206b9df9f94e9592244917", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "fda1b600401ec21e8dc183408d06091b358a02c4", "title": "A Systematic Literature Review of Decision-Making and Control Systems for Autonomous and Social Robots", "abstract": "In the last years, considerable research has been carried out to develop robots that can improve our quality of life during tedious and challenging tasks. In these contexts, robots operating without human supervision open many possibilities to assist people in their daily activities. When autonomous robots collaborate with humans, social skills are necessary for adequate communication and cooperation. Considering these facts, endowing autonomous and social robots with decision-making and control models is critical for appropriately fulfiling their initial goals. This manuscript presents a systematic review of the evolution of decision-making systems and control architectures for autonomous and social robots in the last three decades. These architectures have been incorporating new methods based on biologically inspired models and Machine Learning to enhance these systems’ possibilities to developed societies. The review explores the most novel advances in each application area, comparing their most essential features. Additionally, we describe the current challenges of software architecture devoted to action selection, an analysis not provided in similar reviews of behavioural models for autonomous and social robots. Finally, we present the future directions that these systems can take in the future.", "year": 2023, "publicationDate": "2023-03-26", "publicationTypes": ["JournalArticle", "Review"], "venue": "International Journal of Social Robotics", "journal": {"name": "International Journal of Social Robotics", "pages": "745-789", "volume": "15"}, "citationCount": 53, "referenceCount": 181, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s12369-023-00977-3.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2314498826", "name": "Marcos Maroto-Gómez"}, {"authorId": "1401846718", "name": "F. Alonso-Martín"}, {"authorId": "5992147", "name": "M. Malfaz"}, {"authorId": "1413902456", "name": "Álvaro Castro-González"}, {"authorId": "2439331", "name": "J. C. Castillo"}, {"authorId": "1853452", "name": "M. Salichs"}], "url": "https://www.semanticscholar.org/paper/fda1b600401ec21e8dc183408d06091b358a02c4", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "2803494ae83ae2959cdc3605100a88d45fd65e9b", "title": "Learning robust autonomous navigation and locomotion for wheeled-legged robots", "abstract": "Autonomous wheeled-legged robots have the potential to transform logistics systems, improving operational efficiency and adaptability in urban environments. Navigating urban environments, however, poses unique challenges for robots, necessitating innovative solutions for locomotion and navigation. These challenges include the need for adaptive locomotion across varied terrains and the ability to navigate efficiently around complex dynamic obstacles. This work introduces a fully integrated system comprising adaptive locomotion control, mobility-aware local navigation planning, and large-scale path planning within the city. Using model-free reinforcement learning (RL) techniques and privileged learning, we developed a versatile locomotion controller. This controller achieves efficient and robust locomotion over various rough terrains, facilitated by smooth transitions between walking and driving modes. It is tightly integrated with a learned navigation controller through a hierarchical RL framework, enabling effective navigation through challenging terrain and various obstacles at high speed. Our controllers are integrated into a large-scale urban navigation system and validated by autonomous, kilometer-scale navigation missions conducted in Zurich, Switzerland, and Seville, Spain. These missions demonstrate the system’s robustness and adaptability, underscoring the importance of integrated control systems in achieving seamless navigation in complex environments. Our findings support the feasibility of wheeled-legged robots and hierarchical RL for autonomous navigation, with implications for last-mile delivery and beyond. Data-driven approaches enable efficient large-scale autonomous navigation of wheeled-legged robots in urban environments. Editor’s summary Last-mile deliveries in urban areas lead to increasing traffic problems and supply chain issues. By converting to robotic deliveries, routes can move from the street to alternate pathways, but traditional legged robots lack the necessary efficiency and battery life. By augmenting a legged robot with wheels, Lee et al. used hybrid wheeled-legged locomotion to improve the cost of transport while rolling on flat surfaces yet still allowing for legged navigation over obstacles like stairs. Using various reinforcement learning techniques, the robot was trained to smoothly transition between walking and driving modes and to navigate challenging terrain and dynamic obstacles including pedestrians. The robot was tested for large-scale navigation through an autonomous trek of more than 10 kilometers in Zurich, Switzerland, and Seville, Spain. The hybrid wheeled-legged platform successfully addressed many challenges associated with robotic urban mobility. —Melisa Yashinski", "year": 2024, "publicationDate": "2024-04-24", "publicationTypes": ["JournalArticle"], "venue": "Science Robotics", "journal": {"name": "Science Robotics", "volume": "9"}, "citationCount": 183, "referenceCount": 82, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2405.01792", "fieldsOfStudy": ["Computer Science", "Engineering", "Medicine"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2248719465", "name": "Joonho Lee"}, {"authorId": "7743670", "name": "Marko Bjelonic"}, {"authorId": "2079384841", "name": "Alexander Reske"}, {"authorId": "7153704", "name": "Lorenz Wellhausen"}, {"authorId": "1825794582", "name": "Takahiro Miki"}, {"authorId": "2247860967", "name": "Marco Hutter"}], "url": "https://www.semanticscholar.org/paper/2803494ae83ae2959cdc3605100a88d45fd65e9b", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "e601843d16646ff63e80c73d3f75f14fb650af03", "title": "Data-Driven Predictive Control for Autonomous Systems", "abstract": "In autonomous systems, the ability to make forecasts and cope with uncertain predictions is synonymous with intelligence. Model predictive control (MPC) is an established control methodology that systematically uses forecasts to compute real-time optimal control decisions. In MPC, at each time step an optimization problem is solved over a moving horizon. The objective is to find a control policy that minimizes a predicted performance index while satisfying operating constraints. Uncertainty in MPC is handled by optimizing over multiple uncertain forecasts. In this case, performance index and operating constraints take the form of functions defined over a probability space, and the resulting technique is called stochastic MPC. Our research over the past 10 years has focused on predictive control design methods that systematically handle uncertain forecasts in autonomous and semiautonomous systems. In the first part of this article, we present an overview of the approach we use, its main advantages, and its challenges. In the second part, we present our most recent results on data-driven predictive control. We show how to use data to efficiently formulate stochastic MPC problems and autonomously improve performance in repetitive tasks. The proposed framework is able to handle a large set of predicted scenarios in real time and learn from historical data.", "year": 2018, "publicationDate": "2018-05-28", "publicationTypes": ["JournalArticle", "Review"], "venue": "Annu. Rev. Control. Robotics Auton. Syst.", "journal": {"name": "Annu. Rev. Control. Robotics Auton. Syst.", "pages": "259-286", "volume": "1"}, "citationCount": 97, "referenceCount": 0, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://www.annualreviews.org/doi/pdf/10.1146/annurev-control-060117-105215", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "3468386", "name": "Ugo Rosolia"}, {"authorId": "46447792", "name": "Xiaojing Zhang"}, {"authorId": "40547932", "name": "F. Borrelli"}], "url": "https://www.semanticscholar.org/paper/e601843d16646ff63e80c73d3f75f14fb650af03", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "5895c39ed37b2f88ade4cce020173407a2785c38", "title": "Formal verification of ethical choices in autonomous systems", "abstract": "Autonomous systems such as unmanned vehicles are beginning to operate within society. All participants in society are required to follow specific regulations and laws. An autonomous system cannot be an exception. Inevitably an autonomous system will find itself in a situation in which it needs to not only choose to obey a rule or not, but also make a complex ethical decision. However, there exists no obvious way to implement the human understanding of ethical behaviour in computers. Even if we enable autonomous systems to distinguish between more and less ethical alternatives, how can we be sure that they would choose right? We consider autonomous systems with a hybrid architecture in which the highest level of reasoning is executed by a rational (BDI) agent. For such a system, formal verification has been used successfully to prove that specific rules of behaviour are observed when making decisions. We propose a theoretical framework for ethical plan selection that can be formally verified. We implement a rational agent that incorporates a given ethical policy in its plan selection and show that we can formally verify that the agent chooses to execute, to the best of its beliefs, the most ethical available plan.", "year": 2016, "publicationDate": "2016-03-01", "publicationTypes": ["JournalArticle"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "pages": "1-14", "volume": "77"}, "citationCount": 231, "referenceCount": 53, "influentialCitationCount": 7, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S0921889015003000/pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Philosophy", "source": "s2-fos-model"}], "authors": [{"authorId": "1751408", "name": "Louise Dennis"}, {"authorId": "143805379", "name": "Michael Fisher"}, {"authorId": "2013035", "name": "M. Slavkovik"}, {"authorId": "35022905", "name": "M. Webster"}], "url": "https://www.semanticscholar.org/paper/5895c39ed37b2f88ade4cce020173407a2785c38", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "a595767fa35bcc84362f629fbc4d2d9b05d7342a", "title": "A survey of deep learning techniques for autonomous driving", "abstract": "The last decade witnessed increasingly rapid progress in self‐driving vehicle technology, mainly backed up by advances in the area of deep learning and artificial intelligence (AI). The objective of this paper is to survey the current state‐of‐the‐art on deep learning technologies used in autonomous driving. We start by presenting AI‐based self‐driving architectures, convolutional and recurrent neural networks, as well as the deep reinforcement learning paradigm. These methodologies form a base for the surveyed driving scene perception, path planning, behavior arbitration, and motion control algorithms. We investigate both the modular perception‐planning‐action pipeline, where each module is built using deep learning methods, as well as End2End systems, which directly map sensory information to steering commands. Additionally, we tackle current challenges encountered in designing AI architectures for autonomous driving, such as their safety, training data sources, and computational hardware. The comparison presented in this survey helps gain insight into the strengths and limitations of deep learning and AI approaches for autonomous driving and assist with design choices.", "year": 2019, "publicationDate": "2019-10-17", "publicationTypes": ["JournalArticle", "Review"], "venue": "J. Field Robotics", "journal": {"name": "Journal of Field Robotics", "pages": "362 - 386", "volume": "37"}, "citationCount": 1753, "referenceCount": 173, "influentialCitationCount": 40, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1910.07738", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2150397", "name": "S. Grigorescu"}, {"authorId": "52000784", "name": "Bogdan Trasnea"}, {"authorId": "2462122", "name": "Tiberiu T. Cocias"}, {"authorId": "2738117", "name": "G. Măceșanu"}], "url": "https://www.semanticscholar.org/paper/a595767fa35bcc84362f629fbc4d2d9b05d7342a", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "a203b9414f0d51612ddc57d3ef54373f1a835870", "title": "Lidar Point Cloud Compression, Processing and Learning for Autonomous Driving", "abstract": "As technology advances, cities are getting smarter. Smart mobility is the key element in smart cities and Autonomous Driving (AV) are an essential part of smart mobility. However, the vulnerability of unmanned vehicles can also affect the value of life and human safety. In this paper, we provide a comprehensive analysis of 3D Point-Cloud (3DPC) processing and learning in terms of development, advancement, and performance for the AV system. 3DPC has recently attracted growing interest due to its extensive applications, such as autonomous driving, computer vision, and robotics. Light Detection and Ranging Sensors (LiDAR) is one of the most significant sensors in AV, which collects 3DPC that can accurately capture the outer surfaces of scenes and objects. Learning and processing tools in the 3DPC are essential for creating maps, perceptions, and localization devices in AV. The intention behind 3DPC learning and practical processing tools is to be considered the most essential modules to create, locate, and perceive maps in an AV system. The goal of the study is to know “what has been tested in AV system so far and what is necessary to make it safer and more practical in AV system.” We also provide insights into the necessary open problems that are required to be resolved in the future.", "year": 2023, "publicationDate": "2023-01-01", "publicationTypes": ["JournalArticle"], "venue": "IEEE transactions on intelligent transportation systems (Print)", "journal": {"name": "IEEE Transactions on Intelligent Transportation Systems", "pages": "962-979", "volume": "24"}, "citationCount": 80, "referenceCount": 182, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://e-space.mmu.ac.uk/631072/1/Lidar%20point%20Cloud%20Compression.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "145642427", "name": "R. Abbasi"}, {"authorId": "47311590", "name": "A. Bashir"}, {"authorId": "2129863800", "name": "Hasan J. Alyamani"}, {"authorId": "2113925981", "name": "Farhan Amin"}, {"authorId": "41015669", "name": "Jaehyeok Doh"}, {"authorId": "2136188279", "name": "Jianwen Chen"}], "url": "https://www.semanticscholar.org/paper/a203b9414f0d51612ddc57d3ef54373f1a835870", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "479bd6d4a871fd2e0b718c8a106f86acda2878b0", "title": "Autonomous Sweet Pepper Harvesting for Protected Cropping Systems", "abstract": "In this letter, we present a new robotic harvester (Harvey) that can autonomously harvest sweet pepper in protected cropping environments. Our approach combines effective vision algorithms with a novel end-effector design to enable successful harvesting of sweet peppers. Initial field trials in protected cropping environments, with two cultivar, demonstrate the efficacy of this approach achieving a 46% success rate for unmodified crop, and 58% for modified crop. Furthermore, for the more favourable cultivar we were also able to detach 90% of sweet peppers, indicating that improvements in the grasping success rate would result in greatly improved harvesting performance.", "year": 2017, "publicationDate": "2017-01-19", "publicationTypes": ["JournalArticle"], "venue": "IEEE Robotics and Automation Letters", "journal": {"name": "IEEE Robotics and Automation Letters", "pages": "872-879", "volume": "2"}, "citationCount": 234, "referenceCount": 28, "influentialCitationCount": 9, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1706.02023", "fieldsOfStudy": ["Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Agricultural and Food Sciences", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2355154", "name": "Christopher F. Lehnert"}, {"authorId": "145240837", "name": "Andrew English"}, {"authorId": "49872143", "name": "C. McCool"}, {"authorId": "3469182", "name": "Adam W. Tow"}, {"authorId": "2068824789", "name": "Tristan Perez"}], "url": "https://www.semanticscholar.org/paper/479bd6d4a871fd2e0b718c8a106f86acda2878b0", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "d8b70b386b616663388e5d7b5478d889653bb020", "title": "Towards autonomous selective harvesting: A review of robot perception, robot design, motion planning and control", "abstract": "This paper provides an overview of the current state‐of‐the‐art in selective harvesting robots (SHRs) and their potential for addressing the challenges of global food production. SHRs have the potential to increase productivity, reduce labor costs, and minimize wastage by selectively harvesting only ripe fruits and vegetables. The paper discusses the main components of SHRs, including perception, grasping, cutting, motion planning, and control. It also highlights the challenges in developing SHR technologies, particularly in the areas of robot design, motion planning, and control. The paper also discusses the potential benefits of integrating artificial intelligence and soft robots and data‐driven methods to enhance the performance and robustness of SHR systems. Finally, the paper identifies several open research questions in the field and highlights the need for further research and development efforts to advance SHR technologies to meet the challenges of global food production. Overall, this paper provides a starting point for researchers and practitioners interested in developing SHRs and highlights the need for more research in this field.", "year": 2023, "publicationDate": "2023-04-19", "publicationTypes": ["JournalArticle", "Review"], "venue": "J. Field Robotics", "journal": {"name": "Journal of Field Robotics", "pages": "2247 - 2279", "volume": "41"}, "citationCount": 82, "referenceCount": 167, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rob.22230", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Agricultural and Food Sciences", "source": "s2-fos-model"}], "authors": [{"authorId": "2179188659", "name": "S. VishnuRajendran"}, {"authorId": "2387867288", "name": "Bappaditya Debnath"}, {"authorId": "28326483", "name": "Sariah Mghames"}, {"authorId": "1721597818", "name": "Willow Mandil"}, {"authorId": "3024462", "name": "Soran Parsa"}, {"authorId": "144578781", "name": "S. Parsons"}, {"authorId": "2053816690", "name": "Amir Ghalamzan-E"}], "url": "https://www.semanticscholar.org/paper/d8b70b386b616663388e5d7b5478d889653bb020", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "96251898862512c7f765f8bfa7b190ebf38b906e", "title": "TUM autonomous motorsport: An autonomous racing software for the Indy Autonomous Challenge", "abstract": "For decades, motorsport has been an incubator for innovations in the automotive sector and brought forth systems, like, disk brakes or rearview mirrors. Autonomous racing series such as Roborace, F1Tenth, or the Indy Autonomous Challenge (IAC) are envisioned as playing a similar role within the autonomous vehicle sector, serving as a proving ground for new technology at the limits of the autonomous systems capabilities. This paper outlines the software stack and approach of the TUM Autonomous Motorsport team for their participation in the IAC, which holds two competitions: A single‐vehicle competition on the Indianapolis Motor Speedway and a passing competition at the Las Vegas Motor Speedway. Nine university teams used an identical vehicle platform: A modified Indy Lights chassis equipped with sensors, a computing platform, and actuators. All the teams developed different algorithms for object detection, localization, planning, prediction, and control of the race cars. The team from Technical University of Munich (TUM) placed first in Indianapolis and secured second place in Las Vegas. During the final of the passing competition, the TUM team reached speeds and accelerations close to the limit of the vehicle, peaking at around 270 km h − 1 $270\\,\\text{km\\hspace{0.05em}h}{}^{-1}$ and 28 m s − 2 $28\\,ms{}^{-2}$ . This paper will present details of the vehicle hardware platform, the developed algorithms, and the workflow to test and enhance the software applied during the 2‐year project. We derive deep insights into the autonomous vehicle's behavior at high speed and high acceleration by providing a detailed competition analysis. On the basis of this, we deduce a list of lessons learned and provide insights on promising areas of future work based on the real‐world evaluation of the displayed concepts.", "year": 2022, "publicationDate": "2022-05-31", "publicationTypes": ["JournalArticle"], "venue": "J. Field Robotics", "journal": {"name": "Journal of Field Robotics", "pages": "783 - 809", "volume": "40"}, "citationCount": 100, "referenceCount": 100, "influentialCitationCount": 5, "isOpenAccess": true, "openAccessPdfUrl": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rob.22153", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "144053976", "name": "Johannes Betz"}, {"authorId": "40100725", "name": "Tobias Betz"}, {"authorId": "146704593", "name": "F. Fent"}, {"authorId": "1380396991", "name": "Maximilian Geisslinger"}, {"authorId": "52221367", "name": "Alexander Heilmeier"}, {"authorId": "147318116", "name": "Leonhard Hermansdorfer"}, {"authorId": "143662934", "name": "T. Herrmann"}, {"authorId": "104081148", "name": "Sebastian Huch"}, {"authorId": "2008215840", "name": "Phillip Karle"}, {"authorId": "2717687", "name": "M. Lienkamp"}, {"authorId": "144672265", "name": "B. Lohmann"}, {"authorId": "2064896360", "name": "Felix Nobis"}, {"authorId": "2153713095", "name": "Levent Ogretmen"}, {"authorId": "1573599216", "name": "Matthias Rowold"}, {"authorId": "2150096541", "name": "Florian Sauerbeck"}, {"authorId": "32303219", "name": "Tim Stahl"}, {"authorId": "2066895308", "name": "Rainer Trauth"}, {"authorId": "2167156261", "name": "Frederik Werner"}, {"authorId": "115928719", "name": "Alexander Wischnewski"}], "url": "https://www.semanticscholar.org/paper/96251898862512c7f765f8bfa7b190ebf38b906e", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "9d88a9cd8c76843f491bec63ce0b178932899fd7", "title": "A Survey of Deep RL and IL for Autonomous Driving Policy Learning", "abstract": "Autonomous driving (AD) agents generate driving policies based on online perception results, which are obtained at multiple levels of abstraction, e.g., behavior planning, motion planning and control. Driving policies are crucial to the realization of safe, efficient and harmonious driving behaviors, where AD agents still face substantial challenges in complex scenarios. Due to their successful application in fields such as robotics and video games, the use of deep reinforcement learning (DRL) and deep imitation learning (DIL) techniques to derive AD policies have witnessed vast research efforts in recent years. This paper is a comprehensive survey of this body of work, which is conducted at three levels: First, a taxonomy of the literature studies is constructed from the system perspective, among which five modes of integration of DRL/DIL models into an AD architecture are identified. Second, the formulations of DRL/DIL models for conducting specified AD tasks are comprehensively reviewed, where various designs on the model state and action spaces and the reinforcement learning rewards are covered. Finally, an in-depth review is conducted on how the critical issues of AD applications regarding driving safety, interaction with other traffic participants and uncertainty of the environment are addressed by the DRL/DIL models. To the best of our knowledge, this is the first survey to focus on AD policy learning using DRL/DIL, which is addressed simultaneously from the system, task-driven and problem-driven perspectives. We share and discuss findings, which may lead to the investigation of various topics in the future.", "year": 2021, "publicationDate": "2021-01-06", "publicationTypes": ["JournalArticle", "Review"], "venue": "IEEE transactions on intelligent transportation systems (Print)", "journal": {"name": "IEEE Transactions on Intelligent Transportation Systems", "pages": "14043-14065", "volume": "23"}, "citationCount": 225, "referenceCount": 245, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2101.01993", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2112442843", "name": "Zeyu Zhu"}, {"authorId": "1685737", "name": "Huijing Zhao"}], "url": "https://www.semanticscholar.org/paper/9d88a9cd8c76843f491bec63ce0b178932899fd7", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "c2fb54eb80bcf70592557f2e645005d40761ae3d", "title": "An Autonomous Navigation Framework for Holonomic Mobile Robots in Confined Agricultural Environments", "abstract": "Due to the accelerated growth of the world’s population, food security and sustainable agricultural practices have become essential. The incorporation of Artificial Intelligence (AI)-enabled robotic systems in cultivation, especially in greenhouse environments, represents a promising solution, where the utilization of the confined infrastructure improves the efficacy and accuracy of numerous agricultural duties. In this paper, we present a comprehensive autonomous navigation architecture for holonomic mobile robots in greenhouses. Our approach utilizes the heating system rails to navigate through the crop rows using a single stereo camera for perception and a LiDAR sensor for accurate distance measurements. A finite state machine orchestrates the sequence of required actions, enabling fully automated task execution, while semantic segmentation provides essential cognition to the robot. Our approach has been evaluated in a real-world greenhouse using a custom-made robotic platform, showing its overall efficacy for automated inspection tasks in greenhouses.", "year": 2023, "publicationDate": "2023-10-28", "publicationTypes": ["JournalArticle"], "venue": "Robotics", "journal": {"name": "Robotics", "pages": "146", "volume": "12"}, "citationCount": 25, "referenceCount": 34, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.mdpi.com/2218-6581/12/6/146/pdf?version=1698648711", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Agricultural and Food Sciences", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2051459329", "name": "Kosmas Tsiakas"}, {"authorId": "2176085416", "name": "Alexios Papadimitriou"}, {"authorId": "2221123882", "name": "E. Pechlivani"}, {"authorId": "6104348", "name": "Dimitrios Giakoumis"}, {"authorId": "12149777", "name": "Nikolaos Frangakis"}, {"authorId": "2064761210", "name": "A. Gasteratos"}, {"authorId": "2248479682", "name": "D. Tzovaras"}], "url": "https://www.semanticscholar.org/paper/c2fb54eb80bcf70592557f2e645005d40761ae3d", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "d14d38cdd2aadb2b4d2d5ae224cf313c5ace3d78", "title": "Range Image-based LiDAR Localization for Autonomous Vehicles", "abstract": "Robust and accurate, map-based localization is crucial for autonomous mobile systems. In this paper, we exploit range images generated from 3D LiDAR scans to address the problem of localizing mobile robots or autonomous cars in a map of a large-scale outdoor environment represented by a triangular mesh. We use the Poisson surface reconstruction to generate the mesh-based map representation. Based on the range images generated from the current LiDAR scan and the synthetic rendered views from the mesh-based map, we propose a new observation model and integrate it into a Monte Carlo localization framework, which achieves better localization performance and generalizes well to different environments. We test the proposed localization approach on multiple datasets collected in different environments with different LiDAR scanners. The experimental results show that our method can reliably and accurately localize a mobile system in different environments and operate online at the LiDAR sensor frame rate to track the vehicle pose.", "year": 2021, "publicationDate": "2021-05-25", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2021 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "5802-5808"}, "citationCount": 145, "referenceCount": 35, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2105.12121", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "9728126", "name": "Xieyuanli Chen"}, {"authorId": "1491045741", "name": "Ignacio Vizzo"}, {"authorId": "2228395", "name": "T. Läbe"}, {"authorId": "3350812", "name": "Jens Behley"}, {"authorId": "1722062", "name": "C. Stachniss"}], "url": "https://www.semanticscholar.org/paper/d14d38cdd2aadb2b4d2d5ae224cf313c5ace3d78", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "335ca0fba8342d05c1ce0c5d4502fad6fbf77216", "title": "Advanced planning for autonomous vehicles using reinforcement learning and deep inverse reinforcement learning", "abstract": "Abstract Autonomous vehicles promise to improve traffic safety while, at the same time, increase fuel efficiency and reduce congestion. They represent the main trend in future intelligent transportation systems. This paper concentrates on the planning problem of autonomous vehicles in traffic. We model the interaction between the autonomous vehicle and the environment as a stochastic Markov decision process (MDP) and consider the driving style of an expert driver as the target to be learned. The road geometry is taken into consideration in the MDP model in order to incorporate more diverse driving styles. The desired, expert-like driving behavior of the autonomous vehicle is obtained as follows: First, we design the reward function of the corresponding MDP and determine the optimal driving strategy for the autonomous vehicle using reinforcement learning techniques. Second, we collect a number of demonstrations from an expert driver and learn the optimal driving strategy based on data using inverse reinforcement learning. The unknown reward function of the expert driver is approximated using a deep neural-network (DNN). We clarify and validate the application of the maximum entropy principle (MEP) to learn the DNN reward function, and provide the necessary derivations for using the maximum entropy principle to learn a parameterized feature (reward) function. Simulated results demonstrate the desired driving behaviors of an autonomous vehicle using both the reinforcement learning and inverse reinforcement learning techniques.", "year": 2019, "publicationDate": "2019-04-01", "publicationTypes": ["JournalArticle"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "pages": "1-18", "volume": "114"}, "citationCount": 276, "referenceCount": 44, "influentialCitationCount": 5, "isOpenAccess": true, "openAccessPdfUrl": "http://manuscript.elsevier.com/S0921889018302021/pdf/S0921889018302021.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "9024569", "name": "Changxi You"}, {"authorId": "2459101", "name": "Jianbo Lu"}, {"authorId": "1760459", "name": "Dimitar Filev"}, {"authorId": "144185115", "name": "P. Tsiotras"}], "url": "https://www.semanticscholar.org/paper/335ca0fba8342d05c1ce0c5d4502fad6fbf77216", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "e9ac398696129f657a409d64e2646b7fabfa3219", "title": "Benchmarking Reinforcement Learning Techniques for Autonomous Navigation", "abstract": "Deep reinforcement learning (RL) has brought many successes for autonomous robot navigation. However, there still exists important limitations that prevent real-world use of RL-based navigation systems. For example, most learning approaches lack safety guarantees; and learned navigation systems may not generalize well to unseen environments. Despite a variety of recent learning techniques to tackle these challenges in general, a lack of an open-source benchmark and reproducible learning methods specifically for autonomous navigation makes it difficult for roboticists to choose what learning methods to use for their mobile robots and for learning researchers to identify current shortcomings of general learning methods for autonomous navigation. In this paper, we identify four major desiderata of applying deep RL approaches for autonomous navigation: (D1) reasoning under uncertainty, (D2) safety, (D3) learning from limited trial-and-error data, and (D4) generalization to diverse and novel environments. Then, we explore four major classes of learning techniques with the purpose of achieving one or more of the four desiderata: memory-based neural network architectures (D1), safe RL (D2), model-based RL (D2, D3), and domain randomization (D4). By deploying these learning techniques in a new open-source large-scale navigation benchmark and real-world environments, we perform a comprehensive study aimed at establishing to what extent can these techniques achieve these desiderata for RL-based navigation systems.", "year": 2022, "publicationDate": "2022-10-10", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2023 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "9224-9230"}, "citationCount": 74, "referenceCount": 46, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2210.04839", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1935103531", "name": "Zifan Xu"}, {"authorId": "1720831208", "name": "Bo Liu"}, {"authorId": "2118724825", "name": "Xuesu Xiao"}, {"authorId": "1700648458", "name": "Anirudh Nair"}, {"authorId": "144848112", "name": "P. Stone"}], "url": "https://www.semanticscholar.org/paper/e9ac398696129f657a409d64e2646b7fabfa3219", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "baef0a1859fc0216c89289c69da88d6dc8399fc7", "title": "Planning for Autonomous Cars that Leverage Effects on Human Actions", "abstract": "—Traditionally, autonomous cars make predictions about other drivers’ future trajectories, and plan to stay out of their way. This tends to result in defensive and opaque behaviors. Our key insight is that an autonomous car’s actions will actually affect what other cars will do in response, whether the car is aware of it or not. Our thesis is that we can leverage these responses to plan more efficient and communicative behaviors. We model the interaction between an autonomous car and a human driver as a dynamical system, in which the robot’s actions have immediate consequences on the state of the car, but also on human actions. We model these consequences by approximating the human as an optimal planner, with a reward function that we acquire through Inverse Reinforcement Learning. When the robot plans with this reward function in this dynamical system, it comes up with actions that purposefully change human state: it merges in front of a human to get them to slow down or to reach its own goal faster; it blocks two lanes to get them to switch to a third lane; or it backs up slightly at an intersection to get them to proceed first. Such behaviors arise from the optimization, without relying on hand-coded signaling strategies and without ever explicitly modeling communication. Our user study results suggest that the robot is indeed capable of eliciting desired changes in human state by planning using this dynamical system.", "year": 2016, "publicationDate": "2016-06-18", "publicationTypes": ["JournalArticle"], "venue": "Robotics: Science and Systems Conference", "journal": {"name": "", "volume": "12"}, "citationCount": 558, "referenceCount": 29, "influentialCitationCount": 27, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.15607/rss.2016.xii.029", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1779671", "name": "Dorsa Sadigh"}, {"authorId": "2062932428", "name": "S. Sastry"}, {"authorId": "1775517", "name": "S. Seshia"}, {"authorId": "2745001", "name": "A. Dragan"}], "url": "https://www.semanticscholar.org/paper/baef0a1859fc0216c89289c69da88d6dc8399fc7", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "758c9b796c213143968519805e4f395ebbca6bce", "title": "Dexterous Manipulation from Images: Autonomous Real-World RL via Substep Guidance", "abstract": "Complex and contact-rich robotic manipulation tasks, particularly those that involve multi-fingered hands and underactuated object manipulation, present a significant challenge to any control method. Methods based on reinforcement learning offer an appealing choice for such settings, as they can enable robots to learn to delicately balance contact forces and dexterously reposition objects without strong modeling assumptions. However, running reinforcement learning on real-world dexterous manipulation systems often requires significant manual engineering. This negates the benefits of autonomous data collection and ease of use that reinforcement learning should in principle provide. In this paper, we describe a system for vision-based dexterous manipulation that provides a “programming-free” approach for users to define new tasks and enable robots with complex multi-fingered hands to learn to perform them through interaction. The core principle under-lying our system is that, in a vision-based setting, users should be able to provide high-level intermediate supervision that circumvents challenges in teleoperation or kinesthetic teaching which allows a robot to not only learn a task efficiently but also to autonomously practice. Our system includes a framework for users to define a final task and intermediate sub-tasks with image examples, a reinforcement learning procedure that learns the task autonomously without interventions, and experimental results with a four-finger robotic hand learning multi-stage object manipulation tasks directly in the real world, without simulation, manual modeling, or reward engineering.", "year": 2022, "publicationDate": "2022-12-19", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2023 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "5938-5945"}, "citationCount": 35, "referenceCount": 59, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/2212.09902", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "36303818", "name": "Kelvin Xu"}, {"authorId": "2111375925", "name": "Zheyuan Hu"}, {"authorId": "2197078118", "name": "Ria Doshi"}, {"authorId": "2080122735", "name": "Aaron Rovinsky"}, {"authorId": "2109446216", "name": "Vikash Kumar"}, {"authorId": "144150274", "name": "Abhishek Gupta"}, {"authorId": "1736651", "name": "S. Levine"}], "url": "https://www.semanticscholar.org/paper/758c9b796c213143968519805e4f395ebbca6bce", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "1d3aa6e84299f8d36629e147679614ae09e55d2e", "title": "Agile Autonomous Driving using End-to-End Deep Imitation Learning", "abstract": "We present an end-to-end imitation learning system for agile, off-road autonomous driving using only low-cost sensors. By imitating a model predictive controller equipped with advanced sensors, we train a deep neural network control policy to map raw, high-dimensional observations to continuous steering and throttle commands. Compared with recent approaches to similar tasks, our method requires neither state estimation nor on-the-fly planning to navigate the vehicle. Our approach relies on, and experimentally validates, recent imitation learning theory. Empirically, we show that policies trained with online imitation learning overcome well-known challenges related to covariate shift and generalize better than policies trained with batch imitation learning. Built on these insights, our autonomous driving system demonstrates successful high-speed off-road driving, matching the state-of-the-art performance.", "year": 2017, "publicationDate": "2017-09-21", "publicationTypes": ["JournalArticle"], "venue": "Robotics: Science and Systems Conference", "journal": {"name": "Robotics: Science and Systems XIV"}, "citationCount": 285, "referenceCount": 35, "influentialCitationCount": 8, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.15607/rss.2018.xiv.056", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "32981185", "name": "Yunpeng Pan"}, {"authorId": "1978613", "name": "Ching-An Cheng"}, {"authorId": "19253835", "name": "Kamil Saigol"}, {"authorId": "26365079", "name": "Keuntaek Lee"}, {"authorId": "8073235", "name": "Xinyan Yan"}, {"authorId": "1751063", "name": "Evangelos A. Theodorou"}, {"authorId": "3288815", "name": "Byron Boots"}], "url": "https://www.semanticscholar.org/paper/1d3aa6e84299f8d36629e147679614ae09e55d2e", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "75fca92da207b950a83061536b8d8cb7ad1a2d33", "title": "Generalization through Simulation: Integrating Simulated and Real Data into Deep Reinforcement Learning for Vision-Based Autonomous Flight", "abstract": "Deep reinforcement learning provides a promising approach for vision-based control of real-world robots. However, the generalization of such models depends critically on the quantity and variety of data available for training. This data can be difficult to obtain for some types of robotic systems, such as fragile, small-scale quadrotors. Simulated rendering and physics can provide for much larger datasets, but such data is inherently of lower quality: many of the phenomena that make the real-world autonomous flight problem challenging, such as complex physics and air currents, are modeled poorly or not at all, and the systematic differences between simulation and the real world are typically impossible to eliminate. In this work, we investigate how data from both simulation and the real world can be combined in a hybrid deep reinforcement learning algorithm. Our method uses real-world data to learn about the dynamics of the system, and simulated data to learn a generalizable perception system that can enable the robot to avoid collisions using only a monocular camera. We demonstrate our approach on a real-world nano aerial vehicle collision avoidance task, showing that with only an hour of real-world data, the quadrotor can avoid collisions in new environments with various lighting conditions and geometry. Code, instructions for building the aerial vehicles, and videos of the experiments can be found at github.com/gkahn13/GtS", "year": 2019, "publicationDate": "2019-02-11", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2019 International Conference on Robotics and Automation (ICRA)", "pages": "6008-6014"}, "citationCount": 144, "referenceCount": 48, "influentialCitationCount": 8, "isOpenAccess": true, "openAccessPdfUrl": "http://arxiv.org/pdf/1902.03701", "fieldsOfStudy": ["Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2114072662", "name": "Katie Kang"}, {"authorId": "69879999", "name": "Suneel Belkhale"}, {"authorId": "46292812", "name": "G. Kahn"}, {"authorId": "1689992", "name": "P. Abbeel"}, {"authorId": "1736651", "name": "S. Levine"}], "url": "https://www.semanticscholar.org/paper/75fca92da207b950a83061536b8d8cb7ad1a2d33", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "360a4863bd35767386f1b65c8b152e87cb85f5d5", "title": "Adaptive low-level control of autonomous underwater vehicles using deep reinforcement learning", "abstract": "Abstract Low-level control of autonomous underwater vehicles (AUVs) has been extensively addressed by classical control techniques. However, the variable operating conditions and hostile environments faced by AUVs have driven researchers towards the formulation of adaptive control approaches. The reinforcement learning (RL) paradigm is a powerful framework which has been applied in different formulations of adaptive control strategies for AUVs. However, the limitations of RL approaches have lead towards the emergence of deep reinforcement learning which has become an attractive and promising framework for developing real adaptive control strategies to solve complex control problems for autonomous systems. However, most of the existing applications of deep RL use video images to train the decision making artificial agent but obtaining camera images only for an AUV control purpose could be costly in terms of energy consumption. Moreover, the rewards are not easily obtained directly from the video frames. In this work we develop a deep RL framework for adaptive control applications of AUVs based on an actor-critic goal-oriented deep RL architecture, which takes the available raw sensory information as input and as output the continuous control actions which are the low-level commands for the AUV’s thrusters. Experiments on a real AUV demonstrate the applicability of the stated deep RL approach for an autonomous robot control problem.", "year": 2018, "publicationDate": "2018-09-01", "publicationTypes": ["JournalArticle"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "pages": "71-86", "volume": "107"}, "citationCount": 166, "referenceCount": 88, "influentialCitationCount": 5, "isOpenAccess": true, "openAccessPdfUrl": "https://www.sciencedirect.com/science/article/pii/S0921889018301519", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "10343823", "name": "Ignacio Carlucho"}, {"authorId": "145825862", "name": "M. D. Paula"}, {"authorId": "8120368", "name": "Sen Wang"}, {"authorId": "1711690", "name": "Y. Pétillot"}, {"authorId": "31679407", "name": "G. Acosta"}], "url": "https://www.semanticscholar.org/paper/360a4863bd35767386f1b65c8b152e87cb85f5d5", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "376e77b6758a59e15a33aed022479c6dc91ab978", "title": "Model predictive control of autonomous mobility-on-demand systems", "abstract": "In this paper we present a model predictive control (MPC) approach to optimize vehicle scheduling and routing in an autonomous mobility-on-demand (AMoD) system. In AMoD systems, robotic, self-driving vehicles transport customers within an urban environment and are coordinated to optimize service throughout the entire network. Specifically, we first propose a novel discrete-time model of an AMoD system and we show that this formulation allows the easy integration of a number of real-world constraints, e.g., electric vehicle charging constraints. Second, leveraging our model, we design a model predictive control algorithm for the optimal coordination of an AMoD system and prove its stability in the sense of Lyapunov. At each optimization step, the vehicle scheduling and routing problem is solved as a mixed integer linear program (MILP) where the decision variables are binary variables representing whether a vehicle will 1) wait at a station, 2) service a customer, or 3) rebalance to another station. Finally, by using real-world data, we show that the MPC algorithm can be run in real-time for moderately-sized systems and outperforms previous control strategies for AMoD systems.", "year": 2015, "publicationDate": "2015-09-14", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2016 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "1382-1389"}, "citationCount": 93, "referenceCount": 27, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1509.03985", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "33892534", "name": "Rick Zhang"}, {"authorId": "2460526", "name": "Federico Rossi"}, {"authorId": "2253665957", "name": "Marco Pavone"}], "url": "https://www.semanticscholar.org/paper/376e77b6758a59e15a33aed022479c6dc91ab978", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "eb65977087db2a257e24b7fe683f351577c74a25", "title": "A Dexterous Robotic System for Autonomous Debridement of Osteolytic Bone Lesions in Confined Spaces: Human Cadaver Studies", "abstract": "This article presents a dexterous robotic system for autonomous debridement of osteolytic bone lesions in confined spaces. The proposed system is distinguished from the state-of-the-art orthopedics systems because it combines a rigid-link robot with a continuum manipulator (CM) that enhances reach in difficult-to-access spaces often encountered in surgery. The CM is equipped with flexible debriding instruments and fiber Bragg grating sensors. The surgeon plans on the patient’s preoperative computed tomography and the robotic system performs the task autonomously under the surgeon’s supervision. An optimization-based controller generates control commands on the fly to execute the task while satisfying physical and safety constraints. The system design and controller are discussed and extensive simulation, phantom and human cadaver experiments are carried out to evaluate the performance, workspace, and dexterity in confined spaces. Mean and standard deviation of target placement are 0.5 and 0.18 mm, and the robotic system covers 91% of the workspace behind an acetabular implant in treatment of hip osteolysis, compared to the 54% that is achieved by conventional rigid tools.", "year": 2021, "publicationDate": "2021-07-21", "publicationTypes": ["JournalArticle"], "venue": "IEEE Transactions on robotics", "journal": {"name": "IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society", "pages": "1213 - 1229", "volume": "38"}, "citationCount": 38, "referenceCount": 59, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://ieeexplore.ieee.org/ielx7/8860/9749165/09492035.pdf", "fieldsOfStudy": ["Computer Science", "Medicine"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Medicine", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "14597560", "name": "S. Sefati"}, {"authorId": "51126261", "name": "Rachel A. Hegeman"}, {"authorId": "2591187", "name": "I. Iordachita"}, {"authorId": "1684883", "name": "R. Taylor"}, {"authorId": "145738662", "name": "Mehran Armand"}], "url": "https://www.semanticscholar.org/paper/eb65977087db2a257e24b7fe683f351577c74a25", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "c372bed27217743c1120d82d22a86a41210b098c", "title": "Image processing using Pearson's correlation coefficient: Applications on autonomous robotics", "abstract": null, "year": 2013, "publicationDate": "2013-04-24", "publicationTypes": ["Conference"], "venue": "2013 13th International Conference on Autonomous Robot Systems", "journal": {"name": "2013 13th International Conference on Autonomous Robot Systems", "pages": "1-6"}, "citationCount": 64, "referenceCount": 36, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://hal.archives-ouvertes.fr/hal-00860912/file/Image_Processing_Using_Pearsona_s_Correlation_Coefficient_-_Applications_on_Autonomous_Robotics_final.pdf", "fieldsOfStudy": ["Engineering"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "143737569", "name": "A. M. Neto"}, {"authorId": "2951065", "name": "A. Victorino"}, {"authorId": "1698809", "name": "I. Fantoni"}, {"authorId": "32829403", "name": "D. Zampieri"}, {"authorId": "144516904", "name": "J. V. Ferreira"}, {"authorId": "37474595", "name": "Danilo Alves de Lima"}], "url": "https://www.semanticscholar.org/paper/c372bed27217743c1120d82d22a86a41210b098c", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "5345431e3be7e9ae66bc017ce38c61ad5dd24e4c", "title": "WareVR: Virtual Reality Interface for Supervision of Autonomous Robotic System Aimed at Warehouse Stocktaking", "abstract": "WareVR is a novel human-robot interface based on a virtual reality (VR) application to interact with a heterogeneous robotic system for automated inventory management. We have created an interface to supervise an autonomous robot remotely from a secluded workstation in a warehouse that could benefit during the current pandemic COVID-19 since the stocktaking is a necessary and regular process in warehouses, which involves a group of people. The proposed interface allows regular warehouse workers without experience in robotics to control the heterogeneous robotic system consisting of an unmanned ground vehicle (UGV) and unmanned aerial vehicle (UAV). WareVR provides visualization of the robotic system in a digital twin of the warehouse, which is accompanied by a real-time video stream from the real environment through an onboard UAV camera. Using the WareVR interface, the operator can conduct different levels of stocktaking, monitor the inventory process remotely, and teleoperate the drone for a more detailed inspection. Besides, the developed interface includes remote control of the UAV for intuitive and straightforward human interaction with the autonomous robot for stocktaking. The effectiveness of the VR-based interface was evaluated through the user study in a “visual inspection” scenario.", "year": 2021, "publicationDate": "2021-10-17", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Systems, Man and Cybernetics", "journal": {"name": "2021 IEEE International Conference on Systems, Man, and Cybernetics (SMC)", "pages": "2139-2145"}, "citationCount": 29, "referenceCount": 23, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2110.11052", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "71720009", "name": "I. Kalinov"}, {"authorId": "1387985873", "name": "Daria Trinitatova"}, {"authorId": "48470616", "name": "D. Tsetserukou"}], "url": "https://www.semanticscholar.org/paper/5345431e3be7e9ae66bc017ce38c61ad5dd24e4c", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "005de9020a5e75822a88b50ed511a60a9e803b4b", "title": "Towards an Autonomous Robot-Assistant for Laparoscopy Using Exteroceptive Sensors: Feasibility Study and Implementation", "abstract": null, "year": 2021, "publicationDate": "2021-10-01", "publicationTypes": ["JournalArticle"], "venue": "IEEE Robotics and Automation Letters", "journal": {"name": "IEEE Robotics and Automation Letters", "pages": "6473-6480", "volume": "6"}, "citationCount": 23, "referenceCount": 0, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://hal.science/hal-04079542/document", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Medicine", "source": "s2-fos-model"}], "authors": [{"authorId": "145144839", "name": "J. Sandoval"}, {"authorId": "50539114", "name": "M. Laribi"}, {"authorId": "3870638", "name": "J. Faure"}, {"authorId": "5505546", "name": "C. Brèque"}, {"authorId": "49775852", "name": "J. Richer"}, {"authorId": "48271202", "name": "S. Zeghloul"}], "url": "https://www.semanticscholar.org/paper/005de9020a5e75822a88b50ed511a60a9e803b4b", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "8ea8df252347b608b49f92baac7a925b63af24f2", "title": "Scalable Multi-Task Imitation Learning with Autonomous Improvement", "abstract": "While robot learning has demonstrated promising results for enabling robots to automatically acquire new skills, a critical challenge in deploying learning-based systems is scale: acquiring enough data for the robot to effectively generalize broadly. Imitation learning, in particular, has remained a stable and powerful approach for robot learning, but critically relies on expert operators for data collection. In this work, we target this challenge, aiming to build an imitation learning system that can continuously improve through autonomous data collection, while simultaneously avoiding the explicit use of reinforcement learning, to maintain the stability, simplicity, and scalability of supervised imitation. To accomplish this, we cast the problem of imitation with autonomous improvement into a multi-task setting. We utilize the insight that, in a multi-task setting, a failed attempt at one task might represent a successful attempt at another task. This allows us to leverage the robot’s own trials as demonstrations for tasks other than the one that the robot actually attempted. Using an initial dataset of multitask demonstration data, the robot autonomously collects trials which are only sparsely labeled with a binary indication of whether the trial accomplished any useful task or not. We then embed the trials into a learned latent space of tasks, trained using only the initial demonstration dataset, to draw similarities between various trials, enabling the robot to achieve one-shot generalization to new tasks. In contrast to prior imitation learning approaches, our method can autonomously collect data with sparse supervision for continuous improvement, and in contrast to reinforcement learning algorithms, our method can effectively improve from sparse, task-agnostic reward signals.", "year": 2020, "publicationDate": "2020-02-25", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2020 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "2167-2173"}, "citationCount": 39, "referenceCount": 38, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/2003.02636", "fieldsOfStudy": ["Computer Science", "Mathematics"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Mathematics", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "1899992", "name": "Avi Singh"}, {"authorId": "145116380", "name": "Eric Jang"}, {"authorId": "17818078", "name": "A. Irpan"}, {"authorId": "2435984", "name": "Daniel Kappler"}, {"authorId": "35904540", "name": "Murtaza Dalal"}, {"authorId": "1736651", "name": "S. Levine"}, {"authorId": "30559411", "name": "Mohi Khansari"}, {"authorId": "46881670", "name": "Chelsea Finn"}], "url": "https://www.semanticscholar.org/paper/8ea8df252347b608b49f92baac7a925b63af24f2", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "88eb490ff3c803a29747a809a8721acd805bb4d6", "title": "A Multi-task Convolutional Neural Network for Autonomous Robotic Grasping in Object Stacking Scenes", "abstract": "Autonomous robotic grasping plays an important role in intelligent robotics. However, how to help the robot grasp specific objects in object stacking scenes is still an open problem, because there are two main challenges for autonomous robots: (1) it is a comprehensive task to know what and how to grasp; (2) it is hard to deal with the situations in which the target is hidden or covered by other objects. In this paper, we propose a multi-task convolutional neural network for autonomous robotic grasping, which can help the robot find the target, make the plan for grasping and finally grasp the target step by step in object stacking scenes. We integrate vision-based robotic grasping detection and visual manipulation relationship reasoning in one single deep network and build the autonomous robotic grasping system. Experimental results demonstrate that with our model, Baxter robot can autonomously grasp the target with a success rate of 90.6%, 71.9% and 59.4% in object cluttered scenes, familiar stacking scenes and complex stacking scenes respectively.", "year": 2018, "publicationDate": "2018-09-19", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE/RJS International Conference on Intelligent RObots and Systems", "journal": {"name": "2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)", "pages": "6435-6442"}, "citationCount": 80, "referenceCount": 21, "influentialCitationCount": 9, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1809.07081", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "7214209", "name": "Hanbo Zhang"}, {"authorId": "2498428", "name": "Xuguang Lan"}, {"authorId": "118108941", "name": "Cedar Site Bai"}, {"authorId": "143692584", "name": "Lipeng Wan"}, {"authorId": "1491094941", "name": "Chenjie Yang"}, {"authorId": "145608731", "name": "Nanning Zheng"}], "url": "https://www.semanticscholar.org/paper/88eb490ff3c803a29747a809a8721acd805bb4d6", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "f1a0633c41fcb146e77e4fdd727c675f4804c86b", "title": "Towards autonomous inspection of concrete deterioration in sewers with legged robots", "abstract": "The regular inspection of sewer systems is essential to assess the level of degradation and to plan maintenance work. Currently, human inspectors must walk through sewers and use their sense of touch to inspect the roughness of the floor and check for cracks. The sense of touch is used since the floor is often covered by (waste) water and biofilm, which renders visual inspection very challenging. In this paper, we demonstrate a robotic inspection system which evaluates concrete deterioration using tactile interaction. We deployed the quadruped robot ANYmal in the sewers of Zurich and commanded it using shared autonomy for several such missions. The inspection itself is realized via a well‐defined scratching motion using one of the limbs on the sewer floor. Inertial and force/torque sensors embedded within specially designed feet captured the resulting vibrations. A pretrained support vector machine (SVM) is evaluated to assess the state of the concrete. The results of the classification are then displayed in a three‐dimensional map recorded by the robot for easy visualization and assessment. To train the SVM we recorded 625 samples with ground truth labels provided by professional sewer inspectors. We make this data set publicly available. We achieved deterioration level estimates within three classes of more than 92% accuracy. During the four deployment missions, we covered a total distance of 300 m and acquired 130 inspection samples.", "year": 2020, "publicationDate": "2020-05-27", "publicationTypes": ["JournalArticle"], "venue": "J. Field Robotics", "journal": {"name": "Journal of Field Robotics", "pages": "1314 - 1327", "volume": "37"}, "citationCount": 60, "referenceCount": 38, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://www.research-collection.ethz.ch/bitstream/20.500.11850/417091/1/kolvenbach2020jfr_preprint.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "13990760", "name": "H. Kolvenbach"}, {"authorId": "93121869", "name": "David Wisth"}, {"authorId": "2070325739", "name": "Russell Buchanan"}, {"authorId": "151017393", "name": "Giorgio Valsecchi"}, {"authorId": "16099155", "name": "R. Grandia"}, {"authorId": "5665874", "name": "M. Fallon"}, {"authorId": "14349870", "name": "Marco Hutter"}], "url": "https://www.semanticscholar.org/paper/f1a0633c41fcb146e77e4fdd727c675f4804c86b", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "5f7dccf3dc975bc0359eb0921b40af31081e359d", "title": "An ant-inspired celestial compass applied to autonomous outdoor robot navigation", "abstract": "Abstract Desert ants use the polarization of skylight and a combination of stride and ventral optic flow integration processes to track the nest and food positions when traveling, achieving outstanding performances. Navigation sensors such as global positioning systems and inertial measurement units still have disadvantages such as their low resolution and drift. Taking our inspiration from ants, we developed a 2-pixel celestial compass which computes the heading angle of a mobile robot in the ultraviolet range. The output signals obtained with this optical compass were investigated under various weather and ultraviolet conditions and compared with those obtained on a magnetometer in the vicinity of our laboratory. After being embedded on-board the robot, the sensor was first used to compensate for random yaw disturbances. We then used the compass to keep the Hexabot robot’s heading angle constant in a straight forward walking task over a flat terrain while its walking movements were imposing yaw disturbances. Experiments performed under various meteorological conditions showed the occurrence of steady state heading angle errors ranging from 0 . 3 ∘ (with a clear sky) to 2 . 9 ∘ (under changeable sky conditions). The compass was also tested under canopies and showed a strong ability to determine the robot’s heading while most of the sky was hidden by the foliage. Lastly, a waterproof, mono-pixel version of the sensor was designed and successfully tested in a preliminary underwater benchmark test. These results suggest this new optical compass shows great precision and reliability in a wide range of outdoor conditions, which makes it highly suitable for autonomous robotic outdoor navigation tasks. A celestial compass and a minimalistic optic flow sensor called M 2 APix (based on Michaelis–Menten Auto-adaptive Pixels) were therefore embedded on-board our latest insectoid robot called AntBot, to complete the previously mentioned ant-like homing navigation processes. First the robot was displaced manually and made to return to its starting-point on the basis of its absolute knowledge of the coordinates of this point. Lastly, AntBot was tested in fully autonomous navigation experiments, in which it explored its environment and then returned to base using the same sensory modes as those on which desert ants rely. AntBot produced robust, precise localization performances with a homing error as small as 0.7% of the entire trajectory.", "year": 2019, "publicationDate": "2019-07-01", "publicationTypes": ["JournalArticle"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "pages": "40-56", "volume": "117"}, "citationCount": 67, "referenceCount": 72, "influentialCitationCount": 4, "isOpenAccess": true, "openAccessPdfUrl": "http://manuscript.elsevier.com/S092188901830263X/pdf/S092188901830263X.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "17157288", "name": "Julien Dupeyroux"}, {"authorId": "1712246", "name": "S. Viollet"}, {"authorId": "144367953", "name": "J. Serres"}], "url": "https://www.semanticscholar.org/paper/5f7dccf3dc975bc0359eb0921b40af31081e359d", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "8e69037c499a952e967c25664c6f04539def9cdf", "title": "Evolutionary Modular Robotics: Survey and Analysis", "abstract": "This paper surveys various applications of artificial evolution in the field of modular robots. Evolutionary robotics aims to design autonomous adaptive robots automatically that can evolve to accomplish a specific task while adapting to environmental changes. A number of studies have demonstrated the feasibility of evolutionary algorithms for generating robotic control and morphology. However, a huge challenge faced was how to manufacture these robots. Therefore, modular robots were employed to simplify robotic evolution and their implementation in real hardware. Consequently, more research work has emerged on using evolutionary computation to design modular robots rather than using traditional hand design approaches in order to avoid cognition bias. These techniques have the potential of developing adaptive robots that can achieve tasks not fully understood by human designers. Furthermore, evolutionary algorithms were studied to generate global modular robotic behaviors including; self-assembly, self-reconfiguration, self-repair, and self-reproduction. These characteristics allow modular robots to explore unstructured and hazardous environments. In order to accomplish the aforementioned evolutionary modular robotic promises, this paper reviews current research on evolutionary robotics and modular robots. The motivation behind this work is to identify the most promising methods that can lead to developing autonomous adaptive robotic systems that require the minimum task related knowledge on the designer side.", "year": 2018, "publicationDate": "2018-07-16", "publicationTypes": ["JournalArticle", "Review"], "venue": "Journal of Intelligent and Robotic Systems", "journal": {"name": "Journal of Intelligent & Robotic Systems", "pages": "815 - 828", "volume": "95"}, "citationCount": 101, "referenceCount": 77, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://link.springer.com/content/pdf/10.1007/s10846-018-0902-9.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "9031353", "name": "Reem Alattas"}, {"authorId": "101319940", "name": "Sarosh H. Patel"}, {"authorId": "2837343", "name": "T. Sobh"}], "url": "https://www.semanticscholar.org/paper/8e69037c499a952e967c25664c6f04539def9cdf", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "10b9283146b71ee5d38238eb3b30732a3d2bdbb2", "title": "Learning deep control policies for autonomous aerial vehicles with MPC-guided policy search", "abstract": "Model predictive control (MPC) is an effective method for controlling robotic systems, particularly autonomous aerial vehicles such as quadcopters. However, application of MPC can be computationally demanding, and typically requires estimating the state of the system, which can be challenging in complex, unstructured environments. Reinforcement learning can in principle forego the need for explicit state estimation and acquire a policy that directly maps sensor readings to actions, but is difficult to apply to unstable systems that are liable to fail catastrophically during training before an effective policy has been found. We propose to combine MPC with reinforcement learning in the framework of guided policy search, where MPC is used to generate data at training time, under full state observations provided by an instrumented training environment. This data is used to train a deep neural network policy, which is allowed to access only the raw observations from the vehicle's onboard sensors. After training, the neural network policy can successfully control the robot without knowledge of the full state, and at a fraction of the computational cost of MPC. We evaluate our method by learning obstacle avoidance policies for a simulated quadrotor, using simulated onboard sensors and no explicit state estimation at test time.", "year": 2015, "publicationDate": "2015-09-22", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2016 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "528-535"}, "citationCount": 447, "referenceCount": 43, "influentialCitationCount": 22, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1509.06791", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2146331974", "name": "Tianhao Zhang"}, {"authorId": "46292812", "name": "G. Kahn"}, {"authorId": "1736651", "name": "S. Levine"}, {"authorId": "1689992", "name": "P. Abbeel"}], "url": "https://www.semanticscholar.org/paper/10b9283146b71ee5d38238eb3b30732a3d2bdbb2", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "e99950dd0fef69724bfd7194b1144f3b8bff78b2", "title": "Gridbot: An autonomous robot controlled by a Spiking Neural Network mimicking the brain's navigational system", "abstract": "It is true that the \"best\" neural network is not necessarily the one with the most \"brain-like\" behavior. Understanding biological intelligence, however, is a fundamental goal for several distinct disciplines. Translating our understanding of intelligence to machines is a fundamental problem in robotics. Propelled by new advancements in Neuroscience, we developed a spiking neural network (SNN) that draws from mounting experimental evidence that a number of individual neurons is associated with spatial navigation. By following the brain's structure, our model assumes no initial all-to-all connectivity, which could inhibit its translation to a neuromorphic hardware, and learns an uncharted territory by mapping its identified components into a limited number of neural representations, through spike-timing dependent plasticity (STDP). In our ongoing effort to employ a bioinspired SNN-controlled robot to real-world spatial mapping applications, we demonstrate here how an SNN may robustly control an autonomous robot in mapping and exploring an unknown environment, while compensating for its own intrinsic hardware imperfections, such as partial or total loss of visual input.", "year": 2018, "publicationDate": "2018-07-05", "publicationTypes": ["Book", "JournalArticle", "Conference"], "venue": "Proceedings of the International Conference on Neuromorphic Systems", "journal": {"name": "Proceedings of the International Conference on Neuromorphic Systems"}, "citationCount": 50, "referenceCount": 68, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1807.02155", "fieldsOfStudy": ["Computer Science", "Biology"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Biology", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "51050036", "name": "Guangzhi Tang"}, {"authorId": "2235492", "name": "K. Michmizos"}], "url": "https://www.semanticscholar.org/paper/e99950dd0fef69724bfd7194b1144f3b8bff78b2", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "679710da3386f5d075c281d6fd7af0dbed76bb05", "title": "A Robot to Monitor Nuclear Facilities: Using Autonomous Radiation-Monitoring Assistance to Reduce Risk and Cost", "abstract": "Nuclear facilities often require continuous monitoring to ensure there is no contamination of radioactive materials that might lead to safety or environmental issues. The current approach to radiological monitoring is to use human operators, which is both time consuming and cost inefficient. As with many repetitive, routine tasks, there are considerable opportunities for the process to be improved using autonomous robotic systems.", "year": 2018, "publicationDate": "2018-10-20", "publicationTypes": [], "venue": "IEEE robotics & automation magazine", "journal": {"name": "IEEE Robotics & Automation Magazine"}, "citationCount": 59, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://ieeexplore.ieee.org/ielx7/100/8664496/08574974.pdf", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2073011999", "name": "Benjamin Bird"}, {"authorId": "50412482", "name": "Arron Griffiths"}, {"authorId": "51138613", "name": "Horatio Martin"}, {"authorId": "9209180", "name": "Eduard Codres"}, {"authorId": "2119102927", "name": "Jennifer Jones"}, {"authorId": "46184057", "name": "A. Stancu"}, {"authorId": "1890595", "name": "B. Lennox"}, {"authorId": "144384242", "name": "S. Watson"}, {"authorId": "92703062", "name": "Xavier Poteau"}], "url": "https://www.semanticscholar.org/paper/679710da3386f5d075c281d6fd7af0dbed76bb05", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "d11c629bd2e16c7b61af2c5203aa3c070d590dfe", "title": "A survey of autonomous self-reconfiguration methods for robot-based programmable matter", "abstract": "Abstract While researchers envision exciting applications for metamorphic systems like programmable matter, current solutions to the shape formation problem are still a long way from meeting their requirements. To dive deeper into this issue, we propose an extensive survey of the current state of the art of self/reconfiguration algorithms and underlying models in modular robotic and self-organizing particle systems. We identify three approaches for solving this problem and we compare the different solutions using a synoptic graphical representation. We then close this survey by confronting existing methods to our vision of programmable matter, and by discussing a number of future research directions that would bring us closer to making it a reality.", "year": 2019, "publicationDate": "2019-10-01", "publicationTypes": ["JournalArticle", "Review"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "volume": "120"}, "citationCount": 48, "referenceCount": 60, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "https://hal.archives-ouvertes.fr/hal-02922199/file/b8a688a2-3334-43be-b728-65b416e833b9-author.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Materials Science", "source": "s2-fos-model"}], "authors": [{"authorId": "120219648", "name": "Pierre Thalamy"}, {"authorId": "1734104", "name": "Benoît Piranda"}, {"authorId": "1736041", "name": "J. Bourgeois"}], "url": "https://www.semanticscholar.org/paper/d11c629bd2e16c7b61af2c5203aa3c070d590dfe", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "7f7a7ac84b88b14c968033850c4fc235a84dace2", "title": "Supervised Autonomous Locomotion and Manipulation for Disaster Response with a Centaur-Like Robot", "abstract": "Mobile manipulation tasks are one of the key challenges in the field of search and rescue (SAR) robotics requiring robots with flexible locomotion and manipulation abilities. Since the tasks are mostly unknown in advance, the robot has to adapt to a wide variety of terrains and workspaces during a mission. The centaur-like robot Centauro has a hybrid legged-wheeled base and an anthropomorphic upper body to carry out complex tasks in environments too dangerous for humans. Due to its high number of degrees of freedom, controlling the robot with direct teleoperation approaches is challenging and exhausting. Supervised autonomy approaches are promising to increase quality and speed of control while keeping the flexibility to solve unknown tasks. We developed a set of operator assistance functionalities with different levels of autonomy to control the robot for challenging locomotion and manipulation tasks. The integrated system was evaluated in disaster response scenarios and showed promising performance.", "year": 2018, "publicationDate": "2018-09-18", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE/RJS International Conference on Intelligent RObots and Systems", "journal": {"name": "2018 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)", "pages": "1-8"}, "citationCount": 63, "referenceCount": 28, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1809.06802", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "32356580", "name": "Tobias Klamt"}, {"authorId": "144897139", "name": "Diego Rodriguez"}, {"authorId": "39754718", "name": "Max Schwarz"}, {"authorId": "2056298986", "name": "Christian Lenz"}, {"authorId": "27688401", "name": "D. Pavlichenko"}, {"authorId": "1764200", "name": "David Droeschel"}, {"authorId": "1699019", "name": "Sven Behnke"}], "url": "https://www.semanticscholar.org/paper/7f7a7ac84b88b14c968033850c4fc235a84dace2", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "d2c72dd7df5d349b7daf6d10cd25de5983f4020e", "title": "Toward a Fully Autonomous UAV: Research Platform for Indoor and Outdoor Urban Search and Rescue", "abstract": null, "year": 2012, "publicationDate": "2012-09-04", "publicationTypes": ["JournalArticle"], "venue": "IEEE robotics & automation magazine", "journal": {"name": "IEEE Robotics & Automation Magazine", "pages": "46-56", "volume": "19"}, "citationCount": 822, "referenceCount": 24, "influentialCitationCount": 17, "isOpenAccess": true, "openAccessPdfUrl": "http://mediatum.ub.tum.de/doc/1285852/document.pdf", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "34598337", "name": "Teodor Tomic"}, {"authorId": "40499793", "name": "Korbinian Schmid"}, {"authorId": "1769583", "name": "P. Lutz"}, {"authorId": "3046807", "name": "Andreas Dömel"}, {"authorId": "73776083", "name": "M. Kassecker"}, {"authorId": "1763477", "name": "Elmar Mair"}, {"authorId": "3146832", "name": "I. Grixa"}, {"authorId": "32882253", "name": "Felix Ruess"}, {"authorId": "1787158", "name": "M. Suppa"}, {"authorId": "1791260", "name": "Darius Burschka"}], "url": "https://www.semanticscholar.org/paper/d2c72dd7df5d349b7daf6d10cd25de5983f4020e", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "be85f179c917f4b97dbe403e1f391897e088e6d9", "title": "Autonomous Learning of Object Models on a Mobile Robot", "abstract": null, "year": 2017, "publicationDate": null, "publicationTypes": ["JournalArticle"], "venue": "IEEE Robotics and Automation Letters", "journal": {"name": "IEEE Robotics and Automation Letters", "pages": "26-33", "volume": "2"}, "citationCount": 73, "referenceCount": 23, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://pure-oai.bham.ac.uk/ws/files/25369196/root.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2716924", "name": "Thomas Faulhammer"}, {"authorId": "1829964", "name": "Rares Ambrus"}, {"authorId": "39967356", "name": "Christopher Burbridge"}, {"authorId": "1682587", "name": "M. Zillich"}, {"authorId": "3248522", "name": "J. Folkesson"}, {"authorId": "143939898", "name": "Nick Hawes"}, {"authorId": "1770066", "name": "P. Jensfelt"}, {"authorId": "1742533", "name": "M. Vincze"}], "url": "https://www.semanticscholar.org/paper/be85f179c917f4b97dbe403e1f391897e088e6d9", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "81e4fd9336b5987fe429743c4065c2a2c79bc057", "title": "Intelligent Autonomous Systems", "abstract": null, "year": 1991, "publicationDate": "1991-08-01", "publicationTypes": ["JournalArticle"], "venue": "Robotics Auton. Syst.", "journal": {"name": "Robotics Auton. Syst.", "pages": "83-84", "volume": "7"}, "citationCount": 108, "referenceCount": 0, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "http://www.science.uva.nl/research/ias/alumni/m.sc.theses/theses/RobvandenBogaard.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "2238283836", "name": "Takeo Kanade"}, {"authorId": "3518227", "name": "L. Hertzberger"}, {"authorId": "2261484148", "name": "F. Groen"}], "url": "https://www.semanticscholar.org/paper/81e4fd9336b5987fe429743c4065c2a2c79bc057", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "0136979b004b55090ece003de72b4ac028a8b460", "title": "Online Incremental Learning of the Terrain Traversal Cost in Autonomous Exploration", "abstract": "(cid:151)In this paper, we address motion ef(cid:2)ciency in autonomous robot exploration with multi-legged walking robots that can traverse rough terrains at the cost of lower ef(cid:2)ciency and greater body vibration. We propose a robotic system for online and incremental learning of the terrain traversal cost that is immediately utilized to reason about next navigational goals in building spatial model of the robot surrounding. The traversal cost experienced by the robot is characterized by incrementally constructed Gaussian Processes using Bayesian Committee Machine. During the exploration, the robot builds the spatial terrain model, marks untraversable areas, and leverages the Gaussian Process predictive variance to decide whether to improve the spatial model or decrease the uncertainty of the terrain traversal cost. The feasibility of the proposed approach has been experimentally veri(cid:2)ed in a fully autonomous deployment with the hexapod walking robot.", "year": 2019, "publicationDate": "2019-06-22", "publicationTypes": ["JournalArticle"], "venue": "Robotics: Science and Systems Conference", "journal": {"name": "Robotics: Science and Systems XV"}, "citationCount": 23, "referenceCount": 39, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.15607/rss.2019.xv.040", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "66080155", "name": "Miloš Prágr"}, {"authorId": "144854882", "name": "P. Čížek"}, {"authorId": "2029360721", "name": "J. Bayer"}, {"authorId": "1766210", "name": "J. Faigl"}], "url": "https://www.semanticscholar.org/paper/0136979b004b55090ece003de72b4ac028a8b460", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "89d22f17c63ef1b84d8de20e4b93cf591b8002f9", "title": "Enabling autonomous capabilities in underwater robotics", "abstract": null, "year": 2008, "publicationDate": "2008-10-14", "publicationTypes": ["JournalArticle", "Conference", "Review"], "venue": "2008 IEEE/RSJ International Conference on Intelligent Robots and Systems", "journal": {"name": "2008 IEEE/RSJ International Conference on Intelligent Robots and Systems", "pages": "3628-3634"}, "citationCount": 59, "referenceCount": 21, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "http://www.cim.mcgill.ca/~mrl/pubs/junaed/iros2008Aqua.pdf", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "1765604", "name": "Junaed Sattar"}, {"authorId": "1798721", "name": "G. Dudek"}, {"authorId": "2399055", "name": "O. Chiu"}, {"authorId": "1691052", "name": "Ioannis M. Rekleitis"}, {"authorId": "2310695", "name": "P. Giguère"}, {"authorId": "2057176390", "name": "Alec Mills"}, {"authorId": "2839372", "name": "Nicolas Plamondon"}, {"authorId": "3049498", "name": "C. Prahacs"}, {"authorId": "1679896", "name": "Yogesh A. Girdhar"}, {"authorId": "2002787", "name": "M. Nahon"}, {"authorId": "38253380", "name": "John-Paul Lobos"}], "url": "https://www.semanticscholar.org/paper/89d22f17c63ef1b84d8de20e4b93cf591b8002f9", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "01df112f239b088706d33b31834d7a34c3af6b3b", "title": "Autonomous Battery Exchange of UAVs with a Mobile Ground Base", "abstract": null, "year": 2018, "publicationDate": "2018-05-21", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2018 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "699-705"}, "citationCount": 25, "referenceCount": 19, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://research.utwente.nl/files/103952838/autonomous.pdf", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "144351311", "name": "É. Barrett"}, {"authorId": "8440245", "name": "Mark Reiling"}, {"authorId": "51310521", "name": "S. Mirhassani"}, {"authorId": "51297661", "name": "R. Meijering"}, {"authorId": "51293944", "name": "J. Jager"}, {"authorId": "2708025", "name": "N. Mimmo"}, {"authorId": "32150095", "name": "Flavio Callegati"}, {"authorId": "144471675", "name": "L. Marconi"}, {"authorId": "1770216", "name": "R. Carloni"}, {"authorId": "1711747", "name": "S. Stramigioli"}], "url": "https://www.semanticscholar.org/paper/01df112f239b088706d33b31834d7a34c3af6b3b", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "85cee11e882b89302292087a029acc36e1d6c670", "title": "Learning from demonstration: repetitive movements for autonomous service robotics", "abstract": null, "year": 2004, "publicationDate": "2004-09-28", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE/RJS International Conference on Intelligent RObots and Systems", "journal": {"name": "2004 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (IEEE Cat. No.04CH37566)", "pages": "3495-3500 vol.4", "volume": "4"}, "citationCount": 42, "referenceCount": 18, "influentialCitationCount": 1, "isOpenAccess": true, "openAccessPdfUrl": "http://mediatum.ub.tum.de/doc/1292333/document.pdf", "fieldsOfStudy": ["Engineering", "Computer Science"], "s2FieldsOfStudy": [{"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "40077793", "name": "H. Urbanek"}, {"authorId": "1397935382", "name": "A. Albu-Schäffer"}, {"authorId": "1715782", "name": "Patrick van der Smagt"}], "url": "https://www.semanticscholar.org/paper/85cee11e882b89302292087a029acc36e1d6c670", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "bfe05ed2a4587e1ebad82215a5f31e8110f06968", "title": "Autonomous Adaptive Modification of Unstructured Environments", "abstract": "We present and validate a property-driven autonomous system that modifies its environment to achieve and maintain navigability over a highly irregular 3-dimensional terrain. In our approach we use decision procedures that tie building actions to the terrain model, giving rise to adaptive and robust building behavior. The building algorithm is driven by continuous evaluation and reaction to terrain properties, rather than relying on a structure blueprint. This capability is essential in robotic systems that operate in unstructured outdoor or remote environments, either on their own or as part of a team. We demonstrate the effectiveness of our approach by running a lowcost robot system that can build with compliant bags in a variety of irregular terrains.", "year": 2018, "publicationDate": "2018-06-26", "publicationTypes": ["JournalArticle"], "venue": "Robotics: Science and Systems Conference", "journal": {"name": "Robotics: Science and Systems XIV"}, "citationCount": 22, "referenceCount": 22, "influentialCitationCount": 0, "isOpenAccess": true, "openAccessPdfUrl": "https://doi.org/10.15607/rss.2018.xiv.070", "fieldsOfStudy": ["Computer Science"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}, {"category": "Computer Science", "source": "s2-fos-model"}], "authors": [{"authorId": "51287275", "name": "Maíra Saboia"}, {"authorId": "21156603", "name": "Vivek Thangavelu"}, {"authorId": "51051219", "name": "W. Gosrich"}, {"authorId": "2155409", "name": "N. Napp"}], "url": "https://www.semanticscholar.org/paper/bfe05ed2a4587e1ebad82215a5f31e8110f06968", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "b70ff4c34bf579392eba724dd4251340fd0c6cd1", "title": "Perception-Informed Autonomous Environment Augmentation with Modular Robots", "abstract": "We present a system enabling a modular robot to autonomously build structures in order to accomplish high-level tasks. Building structures allows the robot to surmount large obstacles, expanding the set of tasks it can perform. This addresses a common weakness of modular robot systems, which often struggle to traverse large obstacles. This paper presents the hardware, perception, and planning tools that comprise our system. An environment characterization algorithm identifies features in the environment that can be augmented to create a path between two disconnected regions of the environment. Specially-designed building blocks enable the robot to create structures that can augment the environment to make obstacles traversable. A high-level planner reasons about the task, robot locomotion capabilities, and environment to decide if and where to augment the environment in order to perform the desired task. We validate our system in hardware experiments.", "year": 2017, "publicationDate": "2017-10-05", "publicationTypes": ["JournalArticle", "Conference"], "venue": "IEEE International Conference on Robotics and Automation", "journal": {"name": "2018 IEEE International Conference on Robotics and Automation (ICRA)", "pages": "6818-6824"}, "citationCount": 23, "referenceCount": 18, "influentialCitationCount": 2, "isOpenAccess": true, "openAccessPdfUrl": "https://arxiv.org/pdf/1710.01840", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Computer Science", "source": "s2-fos-model"}, {"category": "Engineering", "source": "s2-fos-model"}], "authors": [{"authorId": "2540733", "name": "Tarik Tosun"}, {"authorId": "10377866", "name": "Jonathan A. Daudelin"}, {"authorId": "3290822", "name": "Gangyuan Jing"}, {"authorId": "1387890355", "name": "H. Kress-Gazit"}, {"authorId": "143903367", "name": "M. Campbell"}, {"authorId": "144123129", "name": "Mark H. Yim"}], "url": "https://www.semanticscholar.org/paper/b70ff4c34bf579392eba724dd4251340fd0c6cd1", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}
{"paperId": "9020833ae7a5f30bfeb1c6d1843c31ad6174b346", "title": "The LRU Rover for Autonomous Planetary Exploration and Its Success in the SpaceBotCamp Challenge", "abstract": null, "year": 2016, "publicationDate": "2016-05-04", "publicationTypes": ["JournalArticle", "Conference"], "venue": "International Conference on Autonomous Robot Systems and Competitions", "journal": {"name": "2016 International Conference on Autonomous Robot Systems and Competitions (ICARSC)", "pages": "7-14"}, "citationCount": 31, "referenceCount": 24, "influentialCitationCount": 3, "isOpenAccess": true, "openAccessPdfUrl": "https://elib.dlr.de/105409/1/sbc_paper_v1.1_elib.pdf", "fieldsOfStudy": ["Computer Science", "Engineering"], "s2FieldsOfStudy": [{"category": "Computer Science", "source": "external"}, {"category": "Engineering", "source": "external"}, {"category": "Engineering", "source": "s2-fos-model"}, {"category": "Environmental Science", "source": "s2-fos-model"}], "authors": [{"authorId": "40573803", "name": "M. J. Schuster"}, {"authorId": "26560690", "name": "Christoph Brand"}, {"authorId": "3407656", "name": "S. Brunner"}, {"authorId": "50737325", "name": "Peter Lehner"}, {"authorId": "2874978", "name": "Josef Reill"}, {"authorId": "48662861", "name": "Sebastian Riedel"}, {"authorId": "1975827", "name": "T. Bodenmüller"}, {"authorId": "38683768", "name": "Kristin Bussmann"}, {"authorId": "2077261955", "name": "Stefan Büttner"}, {"authorId": "3046807", "name": "Andreas Dömel"}, {"authorId": "10678403", "name": "W. Friedl"}, {"authorId": "3146832", "name": "I. Grixa"}, {"authorId": "2337796", "name": "Matthias Hellerer"}, {"authorId": "3335378", "name": "H. Hirschmüller"}, {"authorId": "73776083", "name": "M. Kassecker"}, {"authorId": "1709715", "name": "Zoltán-Csaba Márton"}, {"authorId": "1919045", "name": "Christian Nissler"}, {"authorId": "32882253", "name": "Felix Ruess"}, {"authorId": "1787158", "name": "M. Suppa"}, {"authorId": "35097643", "name": "A. Wedler"}], "url": "https://www.semanticscholar.org/paper/9020833ae7a5f30bfeb1c6d1843c31ad6174b346", "_run_id": "SKH9x2A47fooo0Tof", "_dataset_id": "dnRpTN4da01xVgtxV"}