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  To accompany OpenPhenom, Recursion is releasing the [**RxRx3-core**](https://arxiv.org/abs/2503.20158) dataset, a challenge dataset in phenomics optimized for the research community.
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  RxRx3-core includes labeled images of 735 genetic knockouts and 1,674 small-molecule perturbations drawn from the [RxRx3 dataset](https://www.rxrx.ai/rxrx3),
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- image embeddings computed with [OpenPhenom](https://huggingface.co/recursionpharma/OpenPhenom), and associations between the included small molecules and genes.
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  The dataset contains 6-channel Cell Painting images and associated embeddings from 222,601 wells but is less than 18Gb, making it incredibly accessible to the research community.
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  Mapping the mechanisms by which drugs exert their actions is an important challenge in advancing the use of high-dimensional biological data like phenomics.
 
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  To accompany OpenPhenom, Recursion is releasing the [**RxRx3-core**](https://arxiv.org/abs/2503.20158) dataset, a challenge dataset in phenomics optimized for the research community.
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  RxRx3-core includes labeled images of 735 genetic knockouts and 1,674 small-molecule perturbations drawn from the [RxRx3 dataset](https://www.rxrx.ai/rxrx3),
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+ image embeddings computed with [OpenPhenom](https://huggingface.co/recursionpharma/OpenPhenom), [MAE-L/8](https://arxiv.org/pdf/2404.10242), [MAE-G/8](https://arxiv.org/pdf/2411.02572), and associations between the included small molecules and genes.
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  The dataset contains 6-channel Cell Painting images and associated embeddings from 222,601 wells but is less than 18Gb, making it incredibly accessible to the research community.
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  Mapping the mechanisms by which drugs exert their actions is an important challenge in advancing the use of high-dimensional biological data like phenomics.