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Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Connective Tissue Diseases Systemic Sclerosis Systemic Lupus Erythematosus Patientw with either (1) systemic lupus erythematosus, (2) systemic sclerosis, or (3) other connective tissue diseases at risk of pulmonary hypertension Voluntarily agrees to participate by providing written i... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-70.0, Rhinoplasty Non-steroidal Ant Inflammatory Drugs Opioid Use Patients 18-70 years old undergoing septorhinoplasty or rhinoplasty for either obstructive or aesthetic reasons. All approaches to rhinoplasty and surgical techniques utilized will be included. This will patients that undergo... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-37.0, Unexplained Infertility Unexplained infertility (UI) body mass index (BMI) ≥35 kg/m2 Follicle Stimulating Hormone >10 International Unit /Litter in early follicular phase diagnosed cause of infertility, menstrual cycle irregularity ovarian cysts sever cervical stenosis former IUI ong... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Smoking Cessation Smoking, Cigarette Nicotine Dependence Key 1. Age 18 years or above 2. Daily smoker using 10 or more cigarettes per day 3. Willing to be smoke-free for 7 days 4. Is able to provide written informed consent (in English) to participate in the study and able to underst... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Stage IV Cancer Age of 18 and over, male or female; 2. Patients with histologically confirmed advanced (stage IV) gastric cancer, NSCLC, breast cancer or ovarian cancer, who choose monotherapy of oral vascular targeting drug (apatinib) due to intolerability or inappropriateness of ot... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-50.0, Immune Thrombocytopenia Meet the diagnostic for immune thrombocytopenia. 2. 18-50 years of age; gestational age over 32 weeks; 3. No response to the treatment of glucocorticoids and / or intravenous immunoglobulin (a stable dose of glucocorticoid could be accepted); 4. Platelet transf... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Colitis, Ulcerative Hospitalized patients with known or newly diagnosed moderate to severe ulcerative colitis (as defined by the Mayo score ≥6) Consented within the first 48 hours of initiating IV steroids Risk score of >3 points (pts) Mean stool frequency/24 hrs (<4 = 0 pts, 4-6 = 1... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Chronic Spontaneous Urticaria Male and female patients 18 years or older Clinical and/or histopathological diagnosis of conventional CSU Unresponsive to oral antihistamine therapy Good general health as confirmed by medical history Patients who are willing and capable of cooperating ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Bell's Palsy Facial Nerve Paresis English as primary language Acute unilateral facial palsy without skin lesions which developed within a 72-hour period and is present for 21 days or less Moderate to severe facial palsy [House-Brackmann grade IV or greater] Another cause of facial n... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Infection Heart Failure COPD Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased Resides within either a 5-mile or 20 minute driving radius of emergency department Has capacity to consent to study OR can assent to study a... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Dermatomyositis, Adult Type Must understand the risks and the benefits/purpose of the study and provide signed and dated informed consent Must be 18 years at time of signing the informed consent form Willing to participate in all required evaluations and procedures in the study includ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Ventricular Tachycardia 80 years old, both males and females Single or dual chamber ICD or BiVentricular ICD in situ Ischemic or non-ischemic cardiomyopathy Receive a single shock from their ICD for monomorphic ventricular tachycardia ICD shock for polymorphic VT/VF or inappropriate ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Colitis, Ulcerative Crohn Disease Inflammatory Bowel Diseases Has confirmed diagnosis of CD or UC for at least 2 years prior to enrollment in the study. 2. Has a moderate to severe IBD flare at the time of enrollment or in participant anamnesis within 2 years before enrollment treate... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-70.0, Traumatic Brain Injury Fatigue Cognitive Impairment mTBI 1. Male or female with a diagnosis of mild TBI. 2. At least 6-month post-injury. 3. Ages 18 to 70 years. 4. Lives in same household as paired control that meets inclusion/ 5. Participant is willing and able to give informed co... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Advanced Systemic Mastocytosis Aggressive Systemic Mastocytosis Systemic Mastocytosis With an Associated Hematologic Neoplasm Mast Cell Leukemia Key 1. Patient must have a diagnosis of aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematologic neopla... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Protamine Adverse Reaction ASA physical status 1-3 Schedule for open heart surgery History of allergy to the study drugs or protamine History of previous cardiac surgery or received protamine History of diabetes with insulin therapy | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Triple -Negative Breast Cancer Estrogen Receptor Negative HER2/Neu Negative Anatomic Stage IV Breast Cancer AJCC Progesterone Receptor Negative Have pathologically confirmed diagnosis of unresectable or metastatic TNBC with no curative treatment options Have been informed of other tr... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 50.0-999.0, Polymyalgia Rheumatica Diagnosis of polymyalgia rheumatica (PMR) according to European League Against Rheumatism/American College of Rheumatology classification criteria Patients must be on prednisone of at least 7.5 mg/day (or equivalent) and not exceeding 20 mg/day at screening and... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-99.0, Chronic Lymphocytic Leukemia Age ≥ 18 years of age Diagnosed with CLL To be considered CLL, the subject must have an absolute lymphocytosis in the blood of at least 5,000 lymphocytes per microliter, or bone marrow lymphocytosis greater than or equal to 30% of all nucleated cells Histo... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Pneumocystis Immunocompromised patient with (i) clinical and/or radiological suspicion of PCP, and (ii) bronchial fibroscopy with contributive BAL No immediate life-threatening conditions (estimated life expectancy >12h) No PCP treatment or PCP treatment < 48h Patient hospitalized in... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Gaucher Disease Male or female participants with a confirmed diagnosis of Gaucher disease Participants who are either naïve to treatment or participants that have been treated with another therapeutic agent for Gaucher disease Participants who start VPRIV treatment or transition from ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Cutaneous Mastocytosis Indolent Systemic Mastocytosis Adult, native French patient with cutaneous or indolent systemic mastocytosis and follow-up at Toulouse Patient having given his agreement of non-opposition Minor patient Patient with other forms of mast cell pathology except cut... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Lymphoma DLBCL Lymphoma subtype --No comorbid disease Pregnancy Peptic ulcer Severe cardiac disease Osteoporosis | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Physician's Role Administration, Oral Inpatient Over 18 Able to tolerate oral medications Currently taking one of our eight medications under research intravenously Children (<18) Unable to tolerate an oral medication (or NPO) Severe disease severity (Ex. vasopressor dependent, seiz... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, HIV Disease Chronic Pain Attending physician or advance practice provider in one of the Institute of Advanced Medicine (IAM) clinics Designated PCP for at least 5 patients to whom he/she prescribes opioids Willing and able to adhere to study procedures including randomization, and re... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Small Cell Lung Cancer Patients with an active autoimmune disease requiring systemic treatment within the past 3 months, or a syndrome that requires systemic steroids greater than dexamethasone 2 mg daily (or equivalent) or immunosuppressive agents within the past 3 months will be in... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Acute Lymphoblastic Leukemia in Remission Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Acute Myeloid Leukemia in Remission Chronic Myelomonocytic Leukemia Myelodysplastic Syndrome With Excess Blasts Recurrent Acute Lymphoblastic Leukemia Recurrent Acute Myeloi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Multiple Myeloma Immune System Diseases Written informed consent and HIPAA authorization for release of personal health information. Patients must sign a consent to undergo cell procurement. Written informed consent to enroll in the CAR T-cell therapy trial must be obtained prior to ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Lymphoma Lymphoma, B-Cell Immune System Diseases Immunoproliferative Disorders Lymphatic Diseases for the Study: Unless otherwise noted, subjects must meet all of the following to participate in all stages of this study Written informed consent and HIPAA authorization for release of ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 11.0-13.0, Sleep Sleep Hygiene, Inadequate specify that participants must 1. Be between the ages of 11-13, 2. Be in 6th-8th grades, 3. Reside in one of the targeted public school districts identified by zip code, 4. Attend one of the schools within these districts significant developmental dela... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Shoulder Arthritis Rotator Cuff Tear Arthropathy Subjects who have RSA for cuff tear arthropathy, massive irreparable rotator cuff tear with pseudoparalysis, or primary osteoarthritis Subjects who have a non-reverse total shoulder arthroplasty, RSA for fracture, tendon transfers as p... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Indolent Systemic Mastocytosis Key Patient must have SM, confirmed by Central Pathology Review of BM biopsy, and central review of B and C-findings by WHO diagnostic criteria Patient must have moderate-to-severe symptoms based on minimum mean total symptom score (TSS) of the ISM Symp... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Advanced Malignant Solid Neoplasm KRAS Gene Mutation Ovarian Carcinoma Refractory Malignant Solid Neoplasm Refractory Ovarian Carcinoma All patients have advanced malignancy (high-grade epithelial ovarian cancer or cancer harboring K-RAS mutation), either refractory to standard thera... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-74.0, Indolent Systemic Mastocytosis Participants must meet all of the following to be enrolled in this study: 1. Male or female participant greater than or equal to 18 and < 75 years of age at screening. 2. Enrolled on NIAID protocol 02-I-0277. 3. Documented pathologic diagnosis of ISM. 4.... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Hypertension ≥18 yr SBP ≥130 mmHg or DBP ≥80 mmHg or taking antihypertensive medication regardless of BP with a SBP <160 mmHg and DBP <100 mmHg Free of diagnosed cardiovascular, pulmonary, renal, metabolic, or other chronic diseases or depression Non-smokers for at least 6 mo prior t... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 60.0-80.0, Vitamin D Deficiency Postmenopausal Caucasian Total plasma 25-hydroxy vitamin D < 50 nmol/L Understand oral and written Danish Able to consent Known allergic reaction/intolerance to Vitamin D supplementation / milk products / juice Known chronic kidney disease (creatinine > 90 µmol/L... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Chronic Spontaneous Urticaria Patients with spontaneous chronic urticaria, according to the of the European Academy of Allergology and Clinical Immunology (EAACI) in agreement with the European Dermatology Forum (EDF), and the World Allergy Organization (WAO), corresponding to an ass... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Systemic Lupus Erythematosus Must be 18 years of age or over Must be diagnosed with Systemic Lupus Erythematosus (SLE) Must be exposed to hydroxychloroquine Must be enrolled at participating sites Under 18 years of age Not diagnosed with SLE Not exposed to hydroxychloroquine Not enr... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Taping Ankle Sprains A history of at least one significant ankle sprain The initial sprain must have occurred at least 12 months prior to the study enrolment Was associated with inflammatory symptoms (pain, swelling, etc) Created at least one interrupted day of desired physical activity... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Sjogren's Syndrome Suspicion of Sjogren's syndrome based on 2016 American College of Rheumatology (ACR) criteria Age ≥ 18 years Being affiliated to health insurance Willing to participate Pregnant or breastfeeding women Patient concerned by articles L 1121-5 to L 1121-8 (persons dep... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 15.0-999.0, Aspirin Sensitivity Aspirin-exacerbated Respiratory Disease Aspirin-Induced Angioedema-Urticaria Aspirin Allergy NSAID-Induced Asthma NSAID-Induced Angioedema-Urticaria NSAID-Induced Anaphylactoid Reaction Aspirin-Induced Anaphylactoid Reaction Thai patients with a history of an imme... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Pneumocystis HIV/AIDS Steroid Older than 18 years To have a gasometry at the admission that confirms moderate or severe PCP Patients receiving trimethoprim / sulfamethoxazole in doses of 15 to 20 mg / kg per day from the first 24 hours after admission Patients who have begun adjuvant ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Lupus Erythematosus, Systemic Lupus erythematosus newly diagnosed or active Inactive lupus erythematosus Needing a blood sample for diagnosis or follow up Signed informed consent Other auto immune disease Pregnant or brest feeding Legal protection or protected adults | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Autoimmune Diseases autoimmune or infectious disease | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma Down Syndrome All B-ALL patients must be enrolled on APEC14B1 and consented to Screening (Part A) prior to treatment and enrollment on AALL1731. APEC 14B1 is not a requirement for B-LLy patients. B-LLy patients may directly enroll... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Hypersensitivity, Immediate Perioperative Period Patients having experienced a perioperative immediate hypersensitivity (including the obstetrical setting) according to one grade of the Ring and Messmer clinical scale, for whom The clinical history is known and has been related to pe... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Gout Flare Patients (> 18 years old) with gout flare defined by following items Identification of sodium urate crystals in synovial fluid analysis Or gout flare diagnosis according to Nijmegen (score > 8/13) Man (2 pts) History of flare (2 pts) Flare involving first metatarsophalang... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-45.0, Neonatal Jaundice The mothers are at late 2nd or early 3rd trimester of their pregnancy and agreed to enroll as study participants They are planning to stay in the study village for the next 12 months (if a mother is planning to give birth at her natal home and then return, she will s... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Hodgkin Disease Lymphoma, Large-cell, Anaplastic Male and female participants 18 years or older by the time of enrollment. 2. Histologically confirmed diagnosis of cHL or sALCL. 3. Newly diagnosed participants, or participants with RR cHL or RR sALCL at the time of enrollment, or par... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Systemic Lupus Erythematosus Positive ANA-titer (≥ 1:80) or Anti-dsDNA (≥ 200 IU/ml) or Highly avid-dsDNA autoantibody (≥ 30 IU/ml) Stable immunosuppressive therapy more than 30 days before beginning of the study with steroid (0-20 mg/day) or other immunosuppressive medication like Hy... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 1.0-24.0, B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma Central Nervous System Leukemia Mixed Phenotype Acute Leukemia Testicular Leukemia B-ALL and MPAL patients must be enrolled on APEC14B1 and consented to studies (Part A) prior to treatment and enrollment on AALL1732. Note that cen... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-100.0, Brugada Syndrome Cardiac Arrest Athletes Heart Atrial Fibrillation Ventricular Ectopic Beat Patients with Brugada syndrome requiring risk stratification 2. Patients without Brugada syndrome acting as a control group 1. Patients undergoing ablation with ECGi system for other arrhythmi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 25.0-40.0, Traumatic Brain Injury Neurobehavioral Manifestation Sleep Disorder Fatigue Are 25 to 40 years of age Are active duty service members or veterans May be NIH employees/staff who are either active duty service members or veterans; except for those who are employed by NINR or subordinate... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Heart Failure Salt; Edema heart failure in NYHA 2-3 class patients under optimal and full medical therapy for HF patients treated with CRTd patients without neoplastic diseases patients without inflammatory sistemic diseases decompensated HF unstable HF patients without full anti-HF ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 30.0-75.0, Cardiovascular Diseases Heart Failure Coronary Artery Disease Mesenchymal Stem Cell Transplantation Regenerative Medicine Patients with a diagnosis of coronary disease, performed by coronary angiography, requiring conventional coronary revascularization surgery History of myocardial i... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Hyperkalemia Patient older than 18 years old Patient admitted to the emergency department Patient with local laboratory serum potassium level superior or equal to 6 mmol/l Patient who provide written informed consent prior to participation in the study Hemolysis or thrombocytosis > ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Aging Subjects must be able to walk for 60 minutes in a 90-minute time frame Subjects are apparently free of cardiovascular, metabolic, and renal disease, which includes no signs or symptoms suggestive of cardiovascular, metabolic or renal disease Subjects have no current musculoskel... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Hypersensitivity Reaction ASA 1-2, no allergy and perioperative hypersensitivity reactions during anaesthesia steroid therapy, allergy in medical history, mastocytosis | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Stage IV Non-small Cell Lung Cancer Stage IV Malignant Melanoma of Uvea Stage IV Small Cell Lung Cancer Stage III Malignant Melanoma Cancer patients with stage IV NSCLC or stage IV malignant melanoma Patient must have at least one measurable lesion and the relevant images in order to... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Steroid Dependent Crohn's Disease Patients with biopsy confirmed, active, steroid dependent CD, without nutrient absorbance problems (Definition of steroid dependency: CD being treated with at least 5 mg/day steroids for the last 3 months; an attempt to reduce the dose induces flare ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Kidney Failure Liver transplant recipients >= 18 years old Normal baseline renal dysfunction (GFR > 60 mL/min) Rabbit anti-thymocyte globulin (rATG) induction (cumulative dose 1.5 mg/kg) Indication for transplant: ethanol, hepatitis C, or nonalcoholic steatohepatitis or any combinati... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-99.0, Steroid Refractory GVHD Graft Vs Host Disease Adult men and women who are at least 18 years of age Recipients of their first allogeneic hematopoietic stem cell transplant from any donor source (including bone marrow, mobilized peripheral blood, cord blood) and human leukocyte antigen ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Metastatic Large Cell Neuroendocrine Carcinoma Metastatic Neuroendocrine Carcinoma Metastatic Neuroendocrine Neoplasm Metastatic Small Cell Neuroendocrine Carcinoma Patients must have metastatic, histologically confirmed poorly-differentiated neuroendocrine neoplasms per 2018 World H... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Infection Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased Resides within either a 5-mile or 20 minute driving radius of emergency department Has capacity to consent ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 65.0-999.0, Older Patients Patients aged 65 years and over Admitted for any reason to the hospital via A&E Patients presenting either alone or confused or with a diagnosis of dementia Patients who received the ICCI while in A&E Patients referred to the Dementia Care Team (which support patients ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 1.0-16.0, Peanut Hypersensitivity Age 1-16 years History of immediate hypersensitivity reaction to peanut Evidence of IgE mediated peanut hypersensitivity within a 12 month period of study enrollment SPT with wheal/flare of at least 3 x 6 mm and/or Peanut specific IgE >0.35 kU/L History of life... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-64.0, Schizophrenia Spectrum and Other Psychotic Disorders Age: 18-64 years, both inclusive Diagnosis: schizophrenia spectrum disorder (F20-F29, ICD-10) Outpatient status IQ≤70 as measured by the short form of the Wechsler Adults Intelligence Scale (WAIS) (Wechsler, 1981) History of head i... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 12.0-999.0, Stage IV Prostate Cancer Stage IV Colon Cancer Stage IV Breast Cancer Stage IV Cancer of the Cervix Age: Greater than 12 years Documented histologic evidence of cancer Staged as stage IV World Health Organization (WHO) Performance Status of between 0 and 2 Radiological confirmation o... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Gout Key 1. Females and males, age 18 to 75 years of age. 2. Diagnosis of gout using ACR/EULAR (must have a score of equal to or greater than 8) 3. Subjects must have experienced ≥2 gout flares in the 12 months prior to screening; 4. Subjects that have not changed their urate lowering... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 20.0-60.0, Vitamin D Deficiency Crohn Disease Clinical diagnosis of Crohn's Disease 2. Must be able to swallow tablets 3. Have certain factors increase the risk of surgery in CD current smoking fistulizing and stricturing disease behaviour early steroid use (medical need for steroids for treatme... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-100.0, Clostridium Difficile Infection All consecutive adult patients (inpatients and outpatients) who have a treated first episode or first recurrence of CDI CDI will be defined by a positive PCR for toxin gene and/or detection of toxin by EIA or CCA along with three or more episodes of di... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Acute Graft-Versus-Host Disease (Gvhd) Grade Hematopoietic Cell Transplantation Fecal Microbiota Transplant Men or women ≥ 18 years old Patient has undergone allogeneic hematopoietic cell transplantation from any donor (related or unrelated with any degree of HLA matching) and any do... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Staphylococcal Infections Osteomyelitis CNS Infection Septic Arthritis Diabetic Foot Infection Vertebral Osteomyelitis Abscess Coagulase Negative Staphylococcal Infection are 18 years of age or older were referred to and assessed by an Infectious Disease physician in the form of a cl... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 5.0-17.0, Systemic Lupus Erythematosus Participant must be between 5 and 17 years of age inclusive, at the time of Day 1 Participants who meet the 1997 American College of Rheumatology (ACR) for the classification of SLE Have or have had in series 4 or more of the 11 ACR for the classification o... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Non Hodgkin Lymphoma (NHL) Mantle Cell Lymphoma (MCL) FOR ALL 1. Patients must be aged ≥18 years with relapsed or refractory B-cell non-Hodgkin Lymphoma. 2. Absolute cluster of differentiation 3 (CD3) count ≥50 mm3. 3. Magnetic resonance imaging (MRI) brain and Lumbar Puncture with c... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Beta-Thalassemia Thalassemia Sickle Cell Disease Hematologic Diseases Hemoglobinopathies Genetic Diseases, Inborn Sickle Cell Anemia Subjects or legal representative or guardian (if applicable) must sign and date informed consent form (ICF) Subjects must have received CTX001 infusion... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-70.0, Crohn Disease for Crohn's disease Male or Female ≥18 and ≤70 years old and lives with someone that is involved in daily diet Documented diagnosed of Crohn's Disease sCDAI less than 400 Patients on oral 5-aminosalicylates, mesalamine or sulfasalazine must be on a stable dose for ≥2 wee... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-50.0, Alopecia Areata early localized scalp alopecia areata patients who did not receive any medication for at least 2 months before starting the study Patients who agreed to join the study and signed written consent pregnant, and lactating females and those with unrealistic expectation Al... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.333-25.0, Primary Immune Deficiency Disorder Immune Deficiency Disease Bone Marrow Failure Confirmed diagnosis of Primary Immune Deficiencies Chronic granulomatous disease (CGD) Wiskott-Aldrich syndrome (WAS) Hyper-Immunoglobulin M (IgM) syndrome Common variable immunodeficiency (CVID) Leukocy... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 30.0-70.0, Dental Implant Failed After evaluation, individuals may be allocated into groups according to the characteristics observed, for example: carriers of single implants, patients with overdentures, individuals with systemic diseases, smokers Individuals who need to use or suspend systemi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 13.0-60.0, Psoriasis minimum age 13 years maximum age 60 years both males and females affected with mild, moderate and severe psoriasis hypertension cardiovascular disorders pregnancy lactation renal failure liver failure hypersensitivity to drug | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Kidney Failure Liver transplant recipients ≥ 18 years old Baseline renal dysfunction (GFR ≤ 60 mL/min) Rabbit anti-thymocyte globulin (rATG) induction (cumulative dose 3 mg/kg) Indication for transplant: ethanol, hepatitis C, or nonalcoholic steatohepatitis Increased risk of rejecti... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Recurrent Head and Neck Squamous Cell Carcinoma Head and Neck Cancer Stage IV Voluntary written consent must be given before performance of any study-related procedure not part of standard medical care. 2. Histologically confirmed HNSCC (oral cavity, oropharynx, hypopharynx, larynx) ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Anaphylaxis Being > 18 years old suffered an anaphylactic reaction, regardless of the location or causative allergen transferred alive in an ICU dead within less than one hour after admission | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Acute-graft-versus-host Disease New onset high risk acute GvHD (Ann Arbor score 2/3 as defined in Appendix A) following allogeneic SCT. Any clinical severity in accordance with Glucksberg grade II-IV is eligible. 2. Any donor type (e.g., related, unrelated) or stem cell source (bone ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-22.0, Acute Myeloid Leukemia All patients must be enrolled on APEC14B1 and consented to Screening (Part A) prior to enrollment and treatment on AAML1831. Submission of diagnostic specimens must be done according to the Manual of Procedures). Risk stratification will not be possible without t... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Rheumatoid Arthritis Interstitial Lung Disease Due to Systemic Disease (Disorder) RA ILD The subject has given written consent to participate in the study. 2. Diagnosis of seropositive (i.e., presence of RF and/or anti-CCP antibodies) rheumatoid arthritis (RA) according to the ACR/EUL... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm Refractory Malignant Solid Neoplasm Unresectable Malignant Solid Neoplasm Patients must have histologically confirmed malignancy that is metastatic or unresectable and for which standard curative measures do not ex... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Pelvic Organ Prolapse Stage II-IV pelvic organ prolapse Bothersome bulge symptoms At least 725 MET-minutes/week on International Physical Activity Questionnaire Short Form English-speaking Undergoing treatment of prolapse Surgery occurring at least 7 days from date of randomization (t... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Indolent Systemic Mastocytosis Patient with one of the following documented mastocytosis subtypes (variants): Smouldering Systemic Mastocytosis, Indolent Systemic Mastocytosis 2. An excess of mast cells or a presence of abnormal mast cells in at least two organs (among skin, bone-marr... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 19.0-999.0, Corona Virus Infection Prevention Study 1. Capable of understanding and providing signed informed consent and ability to adhere to the requirements and restrictions of this protocol; 2. Men and Women ≥ 19 years of age unless local laws dictate otherwise; 3. English speaking; 4. Must ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 20.0-50.0, Socket Preservation Systemically healthy individuals within the age group of 20-50 years with presence of teeth with hopeless prognosis requiring extraction Medically compromised patients Subjects who underwent radiotherapy or chemotherapy in the past 12 months Patients having uncont... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-64.0, Covid-19 Virus Disease ETH employee or ETH student and their family members living in the same household at the start of the study Between 18 and 64 years of age at the start of the study Signed informed consent Age over 64 years at the start of the study In quarantine or self-confin... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Cutaneous Mastocytosis Patient with mastocytosis (diagnosis confirmed clinically according to international criteria) Patient with pigmented skin lesions, of moderate to very severe severity (by comparison with a 4-point photographic scale: light, moderate, severe and very severe) Ma... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 3.0-24.0, Nephrotic Syndrome Steroid-Dependent To be eligible for into this study, participants will have to fulfil the following Age between 3 and 24 years Prednison dependent steroid syndrome 0.3-1mg/Kg/day and receive prednisone for at least six months before enrolment. Steroid dependence is ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Bell Palsy Adult patients (≥18 years) diagnosed with BP within 72 hour of onset. 2. Adult patients willing to get treatment, attending follow up visits and signing informed consent Patients treated with antivirals (i.e acyclovir) for any reason simultaneously, such as Herpes Zoster (... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, COVID-19 Age = or > than 18 years; Laboratory-proven COVID-19 infection by RT-PCR in any clinical sample . Time since symptom onset less than 10 days at the time of screening Presence of COVID-19 pneumonia, with a typical, indeterminate or atypical compatible image in a chest tomog... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Oesophageal Cancer Esophageal Stent Stenosis Patients presenting with dysphagia due to a non-operable malignant obstruction of the esophagus or esophagogastric junction including extrinsic malignant compression and recurrence in post-esophagectomy patients Requiring treatment for dys... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Sexual Dysfunction Pelvic Floor Disorders Pelvic Organ Prolapse Urinary Incontinence Constipation being between the ages of 18-65 being a woman having sex partner no smoking, no alcohol physical, psychological, cognitive impairment having a non-Sjögren additional disease malignancy p... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, To Evaluate the Efficacy of Flushing the Uterine Cavity With Lidocaine Before Hysterosalpingo-Foam Sonography to Reduce Procedure-related Pain *all women who were referred for tubal patency evaluation as part of their fertility workup known allergy to lidocaine unprotected intercours... | 0 |
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