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A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Intrusive Memories of Traumatic Event(s) Post Traumatic Stress Disorder Aged 18 or over Clinical work during the COVID-19 pandemic in hospital care facilities (e.g. ICU, ambulance, intermediate care, ward) Experienced at least one traumatic event in relation to their clinical work as... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Carcinoma Thyroid Cancer Thyroid Cancer, Follicular Thyroid Cancer (Follicular Cell) Thyroid Cancer, Papillary BRAF V600E Mutation Positive Histologically or cytologically confirmed thyroid carcinoma of follicular origin (including papillary, follicular, and poorly differenti... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Rectal Cancer All patients with rectal cancer with one or more lateral nodes with a short-axis of ≥7mm. MR images are reviewed by a one of the study radiologists and both the nodes in the internal iliac as the obturator compartment are assessed. The largest node in each compartment i... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Metastatic Breast Cancer Female or Male patients. 2. Age ≥18 years. 3. Signed informed consent prior to any screening procedure. 4. Locally advanced or metastatic breast cancer of any subtype confirmed both pathologically and radiologically (stage IIIb IV disease). 5. The subjects mu... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-75.0, Traumatic Brain Injury (TBI) > 6 months post traumatic brain injury 75 years old ability to walk without physical assistance Self selected walking speed of 0.01-1.0 m/s <18 years old >75 years old self selected walking speed of > 1.0 m/s < 3 months from botulinum toxin injection Abov... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, To Evaluate PACT, a Mobile Application for Improving Engagement in Advance Care Planning Patient (1) diagnosis of poor prognosis advanced cancer defined as locally advanced or metastatic cancer (e.g., pancreaticobiliary, esophagogastric, hepatocellular carcinoma, lung, or gynecologic... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Neoplasia Well-Differentiated Thyroid Cancer Medullary Thyroid Cancer Lymph Node Metastases years of age or older Patients with fine needle aspiration biopsy (FNAb)-proven metastatic cervical lymph nodes at levels I, II, III, IV, V, VI or VII from differentiated thyroid carci... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-90.0, Chronic Kidney Disease Requiring Chronic Dialysis Hyperphosphatemia Signed and dated informed consent form prior to any study specific procedures. 2. Males or females aged 18 to 80 years, inclusive, at Screening (Visit 1). 3. Females must be non-pregnant and non-lactating. 4. Patients... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-65.0, Neck Pain To have neck pain for at least 3 months Turkish literate individual Operation history due to neck pain problems Individuals diagnosed with tumor, infection, ankylosing spondylitis, rheumatoid arthritis or inflammatory diseases, fracture, cauda equina syndrome Pregnancy Indi... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Nodule complicated thyroid nodule less than 18 malignant thyroid nodule | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Triple-Negative Breast Cancer Cohort A Metastatic or locally advanced unresectable, histologically documented TNBC characterized by absence of human epidermal growth factor 2 (HER2), estrogen receptor (ER), and progesterone receptor (PR) expression Only patients with metastatic TNBC ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Femoral Neck Fractures years and older non-displaced femoral neck fracture community ambulator younger than 18 years displaced femoral neck fracture intertrochanteric fracture subtrochanteric fracture | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 20.0-100.0, Thyroid Cancer Thyroid Cancer, Papillary Benign Thyroid Tumor Patients with thyroid nodules who received total or subtotal thyroidectomy Patients aged 20 years and above Patients with any other type of cancer, immunocompromised disease, or autoimmune disease | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-77.0, Thyroid Cancer Atypia of Undetermined Significance FLUS Clinical cytology diagnosis of Bethesda category III (AUS/FLUS) pathological confirmation of thyroid malignancy after surgery pathological confirmation of other thyroid carcinomas, including follicular carcinoma ,medullary carci... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Papillary Thyroid Microcarcinoma Thyroid Thyroid Cancer Age ≥ 18 years A single, cytologically confirmed papillary thyroid microcarcinoma Maximum diameter ≤ 10 mm Declined active surveillance The thyroid lesion must be solid without coarse calcifications greater than 2 mm No US evide... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Papillary Thyroid Cancer Papillary Thyroid Carcinoma Papillary Microcarcinoma of the Thyroid Patients 18 years of age or older Newly diagnosed previously surgically untreated papillary thyroid cancer (PTC) or suspicious for PTC on fine needle aspiration biopsy of the thyroid. PTC mus... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-85.0, Rectal Cancer middle to low-lying rectal adenocarcinoma patients with enlarged lateral lymph node ≥5mm for short diameter in CT and/or MRI other kind of rectal tumor including neuroendocrine and malignant high location rectal cancer recurrent rectal cancer | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 6.0-18.0, Abdominal Wall Defect All patients born with an abdominal wall defect mental disease | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-45.0, Obesity Weight Loss Eating Behavior overweight to obese (BMI 25-45 kg/m2) not currently engaged in exercise or weight loss activities free of any cardiac, pulmonary, or metabolic health conditions able to safely engage in exercise female participants must be premenopausal and not preg... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-75.0, Thyroid Carcinoma Thyroid Nodule (Benign) Ablation; Retina Patients diagnosed with unilateral thyroid carcinoma and contralateral benign nodule confirmed by preoperative ultrasound-guided fine-needle aspiration cytology Patients with contralateral nodules ≤ 20mm and located in the thy... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-75.0, Peripheral T Cell Lymphoma Subjects fully understand and voluntarily participate in this study and sign informed consent; 2. Age ≥18, ≤75 years, no gender limitation; 3. Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) 0-2; 4. Histopathologically confirmed Peripheral ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IIIA Breast Cancer AJCC v8 Anatomic Stage IIIB Breast Cancer AJCC v8 Anatomic Stage IIIC Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 BRCA-Mutated Malignant Neoplasm BRCA-Mutated Metastatic Breast Carcinoma BRCA... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Squamous Cell Carcinoma of Head and Neck Written informed consent given according to ICH/GCP and national/local regulations must be obtained prior to any screening procedures. 2. World Health Organization (WHO) performance status 0-1. 3. Age ≥ 18 years. 4. Patients with a pathologica... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Head Cancer Head Cancer Neck Neck Cancer Head and Neck Squamous Cell Carcinoma HNSCC Pathologically (histologically or cytologically) proven diagnosis of squamous cell carcinoma of the head and neck that has arisen from the oral cavity, oropharynx, nasal cavity, ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Gland Anaplastic Carcinoma Male or female subjects ≥ 18 years of age. 2. Willingness to participate in the study by signing an informed consent form approved by the ethics committee of the KVMT named after N.I. Pirogov St. Petersburg State University. 3. ECOG status 0 or 1 or... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-90.0, Lymphadenopathy Lung Cancer Sarcoidosis Tuberculosis Age >18 years at the time of the procedure Known or suspected lung cancer based on imaging (CT and/or PET/CT) Endosonography (EBUS and/or EUS) indicated for intrathoracic lymph node assessment/sampling according to national and inte... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 12.0-999.0, Locally Advanced Thyroid Gland Carcinoma Malignant Thyroid Gland Neoplasm Poorly Differentiated Thyroid Gland Carcinoma Recurrent Thyroid Gland Carcinoma Thyroid Gland Anaplastic Carcinoma Thyroid Gland Medullary Carcinoma Thyroid Gland Papillary Carcinoma Thyroid Gland Squamous Cell... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 12.0-999.0, Thyroid Cancer Must have histologically confirmed unresectable locally advanced or metastatic MTC and be a candidate for systemic therapy with SOC MKI Must have received no prior systemic anticancer treatment with MKI therapies for advanced or metastatic MTC Must have radiologically ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, ICD ICD Malfunction S/P S-ICD Implantation n/a | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-80.0, Thyroid Diseases Surgery Patients needing surgery for: Benign or indeterminate nodule less than 6 cm in size or; T1 well differentiated papillary carcinoma less than 2 cm in size or; Well-controlled Grave's disease or; Parathyroid adenoma Total thyroid size is 7-8 cm (no more than 10 ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 20.0-70.0, Thyroid Nodule Thyroid Cancer Voice Disorders Patients undergoing open thyroidectomy for thyroid cancer Patients whose tumor size is less than 4cm Patients who are not suspected of surrounding organ involvement (T4) or metastasis to central lymph nodes in preoperative imaging Patients... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Aortic Valve Insufficiency Mitral Valve Insufficiency years of age. Patients with severe aortic regurgitation and patients with severe mitral regurgitation. Patients will discontinue medications 48 hours prior to the study. Women must not be pregnant. Patients must not have an associa... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Connective Tissue Disease Dissecting Aneurysm Ehlers Danlos Syndrome Marfan Syndrome Nail Patella Syndrome Individuals and their family members will be offered enrollment if they have a suspected or established diagnosis of Marfan, Stickler, Ehlers-Danlos, or a closely related syndrom... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 21.0-999.0, Heart Valve Diseases Patients a) 21 years old or older, with b) MR observed with color flow imaging, c) due to organic mitral valve disease demonstrated by Echocardiography (not normal valve as in functional or ischemic MR), c) isolated (no valve disease other than functional tricusp... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Heart Septal Defects, Ventricular Aortic Valve Insufficiency ventricular septal defect patients receiving total repair from Jan, 1987 to Dec, 2002 follow up more than 1 year after operation complex cardiac lesions | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Insufficiency Mitral Valve Regurgitation Mitral Valve Incompetence Mitral Regurgitation Mitral Insufficiency Key Inclusion/ Patients with Grade 3 (moderate to severe) or Grade 4 (severe) mitral regurgitation (MR) based on American Society of Echocardiography guidelines ... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Insufficiency Mitral Valve Regurgitation Mitral Valve Incompetence Mitral Regurgitation Mitral Insufficiency Have moderate to severe mitral regurgitation, symptomatic or asymptomatic with evidence of left ventricular dysfunction Experience regurgitation origination from ... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-72.0, Liver Cirrhosis Liver Transplant Disorder Male and female patients between 18 and 72 years of age Male or female patients who are primary cadaveric liver transplant recipients Cold ischemia time must be <20 hours Females capable of becoming pregnant must have a negative pregnancy test... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Cystoid Macular Edema Adults (ages 18 years or older) with diabetes mellitus Best corrected visual acuity worse than 20/40 but no worse than 20/800 in the study eye Best corrected visual acuity better than or equal to 20/800 in the fellow eye DME in the study eye (eye scheduled to un... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 21.0-80.0, Postoperative Pain Age 21-80 year old ASA Physical Status ASA I and II Mentally competent Intellectually competent Body mass index <35 No severe cardiac diseases No severe pulmonary diseases Unilateral knee disease No other lower extremity joint disease No chronic narcotic therapy or ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Polycystic Ovary Syndrome Probands who meet the following will be enrolled: Menses < 6 per year without confounding meds Not taking confounding medications at the time of hormone analysis, willing to be off confounding medications for required washout period, or able to provide docume... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-65.0, Systemic Lupus Erythematosus Eligible women will be those having any two of the following 1. Amenorrhea of 6 months or more. 2. Serum follicle-stimulating hormone level of 30 IU/L or more. 3. Menopausal symptoms. 4. Age 48 years or older Women older than 65 years. 2. Severe lupus act... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Mitral Regurgitation Coronary Artery Disease Patients undergoing CABG. 2. Patients with moderate functional ischaemic mitral regurgitation without leaflet prolapse Patients with severe LV dysfunction (EF less than 30%). 2. Patients with associated significant aortic valve disease. 3.... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Regurgitation Congestive Heart Failure Cardiomyopathy Patients would be at least 18 years old They will have history of congestive heart failure and be in New York Heart Association Class III or IV Their left ventricular ejection fraction will be less or equal to 30% The... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers Subjects with diagnosed descending thoracic aortic aneurysms or penetrating atherosclerotic ulcers Subjects who are at least 18 years of age Subjects whose anatomy can accommodate the Relay device Subjects who consent t... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 40.0-75.0, Diabetes Mellitus Hypertension Men or women of any racial background Age >= 40 years and <= 75 years SBP>= 130 mmHg and < 140 mmHg or DBP >= 85 mmHg and < 90 mmHg, average of screening and randomisation visits (in absence of any antihypertensive medication) FG >=100 mg/dl (5.6 mmol/l)... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 21.0-80.0, Mitral Valve Insufficiency Dilated Cardiomyopathy Congestive Heart Failure Patients that fulfill surgical set by the 2006 ACC/AHA guidelines for the management of patients with valvular heart disease Symptomatic mitral regurgitation with left ventricular dysfunction (LVEF < or = 40%) ... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-40.0, Marfan Syndrome Age 18-40 Diagnosis of Marfan Syndrome, on the basis of the Ghent Age <18, >40 Women of child-bearing potential not on adequate contraception Serum creatinine of >0.11 A history of intolerance to ACEI Patients on angiotensin receptor blockers Blood pressure >140/90mmH... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Regurgitation Patients with severe isolated mitral regurgitation due to valvular disease Missing written patient consent Active infective endocarditis Relative mitral regurgitation due to left ventricular disease Other moderate to severe dysfunctional valve Previous cardiac s... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Non-union Diaphysary Tibial Fractures Diaphysary tibial non-unions will be included (9 months after first surgery) Major surgery includes exchange nailing, bone grafting, internal fixation, amputation and soft-tissue coverage procedures, such as delayed primary closure and free flaps... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Atrial Fibrillation Indication for open-heart surgery: Mitral valve repair or replacement, evidence of a dilated left atrium History of Atrial Fibrillation Need for emergent cardiac surgery Previous cardiac surgery Preoperative need for an intraaortic balloon pump or intravenous ino... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Insufficiency Heart Failure Symptomatic chronic heart failure, New York Heart Association (NYHA) class II to IIIb Left ventricular ejection fraction of 0.35 due to non-ischemic etiology Evidence by transthoracic echocardiography (TTE) of moderate or severe MR without obv... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Moderate Mitral Regurgitation Patients with ischemic heart disease, who fulfil the indications for CABG, and who also have a moderate ischemic MR. Ischemic MR is defined as mitral regurgitation due to coronary artery disease and not fortuitously associated with it. It is caused eithe... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-80.0, Heart Valve Diseases Patients > 18 years with a clinical condition of mitral valve prosthesis Evidence of prosthesis valve dysfunction (dehisence, endocarditis or thrombus of prosthetic mitral valve) Concomitant aortic valve prosthesis and tricuspid valve prosthesis Presence of > +2 ... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 1.0-999.0, Marfan Syndrome Marfan syndrome with recognized aortic root dilation Patients must be older than one year of age Beta-blocker treatment at least three months Must sign an informed consent form Prior to aortic root surgery Aortic root dimension more than 5.5cm Aortic surgery within 6 ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 20.0-65.0, Mitral Valve Stenosis rheumatic mitral valve stenosis Degenerative mitral valve disease EF<50% atrial fibrillation inconclusive planimetric assessment moderate or severe mitral regurgitation moderate or severe aortic regurgitation history of previous mitral valve commissurotomy or ba... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-55.0, Cholera Age: 15 years Gender: Male (women would be excluded due to difficulties in separation of their urine from stools, particularly in those with severely dehydrated and associated mental obtundation) Duration of diarrhoea: 24 hours or less Clinical signs and symptoms of severe deh... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 1.0-55.0, Marfan Syndrome Diagnosis of MFS: Ghent and genetically proven defect of the FBN1 gene Age: 12 months to 55 years BSA-adjusted aortic z score = or >2 measured at the level of the sinuses of Valsalva at baseline according to Roman's method, or absolute aortic root diameter >38mm for fem... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-42.0, Gestational Diabetes Mellitus 42 years of age at 20-30 weeks of gestation Caucasian or African-American and non-users of medications known to influence carbohydrate metabolism <18 years or >42 years of age non-Caucasian or non-African-American ethnicity use of drugs that could interf... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Cardiovascular Disease Mitral Valve Repair Cerebral Microemboli Cognitive Decline provide informed consent male or female who are 18 years of age or older elective patients to undergo mitral valve repair +/ coronary artery bypass surgery ability to read and write patients with a his... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 25.0-999.0, Marfan Syndrome Age greater than 25 years Clinical Marfan Syndrome Previous aortic or cardiac surgery Pregnancy Renal Insufficiency Medication intolerance | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-50.0, Pregnancy Heart Diseases Potential subjects for the cardiac disease in pregnancy cohort: 1. At least 18 years of age 2. Cardiac disease as per Clark's Maternal Mortality Associated with Pregnancy: Group 1 (mortality less than 1%) atrial septal defect, ventricular septal defect, patent... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 10.0-999.0, Marfan Syndrome years or older Marfan syndrome according to international Signed informed consent Previous surgery of the ascending aorta, or surgery planned Non echogenicity Contre-indication lactose Pregnancy on going or planned within 3 years Breast feeding Participation in anoth... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 10.0-999.0, Marfan Syndrome Patients > 10 years Diagnosis of MFS, according to the Ghent and/or genetically proven FBN1 mutations or linkage Consent obtained (written) either for the patient and for his/her parents (<18y Z-score of the aorta at the level of the sinus of Valsalva ≥2 (BSA adjusted... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Prolapse for MVP patients Male or female subject ≥18 years Affiliation to the French social insurance system Written informed consent Idiopathic MVP defined by the presence of 1) and 2) OR of criterion 3) : 1. Echographic MVP > 2 mm on the left ventricular parasternal l... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Valve Insufficiency Coronary Artery Disease Chronic severe ischemic mitral regurgitation (often with tethering as a major mechanism) in the judgment of the clinical site echocardiographer, assessed by transthoracic echocardiogram. Assessment of mitral regurgitation will be per... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-40.0, Pregnancy Fetal Growth Singleton, viable pregnancy plus 0 plus 6 weeks of gestation Maternal age 18 years BMI 19.0 -29.9kg/m(2) for low risk group; BMI 30.0 0kg/m(2) for obese group Firm LMP LMP-date and ultrasound date match within 5 days for gestation estimates between 8 weeks + 0 d... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-75.0, Aortic Regurgitation Severe aortic regurgitation Successful valve replacement Informed consent Sinus rhythm No comorbidities No bundle branch block No pregnancy Unwillingness to undergo postop. cath diabetes mellitus arterial hypertension bleeding disorder pulmonary hypertension | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-65.0, Cartilage Lesion to the Femoral Condyle Males or females 18 and 65 years of age. 2. Not more than two treatable symptomatic lesions which are NOT posterior; patient must present with pain in the index knee of moderate or severe level (VAS score ≥5) 3. If Female: Actively practicing a ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-55.0, Musculoskeletal Pain Signed and dated informed consent prior to participation Subjects in good health as determined by the Investigator Age 18-55 Willing to abstain from any physical therapy, hard physical work, exercise or sauna during the study observation period (Screening to Final... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, HIV Infection Liver Failure Evidence of Liver Transplantation Age ≥ 18 Documented HIV-1 infection, hepatitis B or C co-infection is allowed Plasma viral load at screening visit below 50 copies per mL for at least 6 months Patient with severe liver failure (Meld Score ≥ 15 and/or refr... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.5-999.0, HIV Infection Rheumatic Disease Cancer Transplant Pediatrics medically recommended influenza A(H1N1) immunization signed informed consent failure or refusal to provide sufficient blood for antibody determination | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-59.0, First Episode Psychosis Aged 18-59 years and meet DSM-IV diagnostic for first episode of schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS as assessed by using the Structured Clinical Interview for DSM-IV, research version Meeting DSM-IV for... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-45.0, Gestational Diabetes Mellitus Age > 18 yrs Gestational age between 6 and 13 weeks from last menstrual period Alcohol < 2 drinks/day Not involved in regular high intensity physical activity Singleton pregnancy Otherwise good health status Type 1 or type 2 diabetes Taking drugs interfe... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-65.0, Metabolic Syndrome Insulin Resistance Adipokines Cytokines for part A: Patients who are included in the obesity surgery program will be recruited if they fulfill the following Age between 18 and 65 years Body mass index (BMI) >40 kg/m2 or BMI > 35 kg/m2 with co-morbidity related to ob... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Metastatic Melanoma ENTRY Locally advanced or metastatic melanoma Measurable Histologically or cytologically confirmed Surgically incurable HLA-A2 positive and tumors that present HLA-A2.1/p53aa264-272 complexes PRIOR/CONCURRENT If prior Proleukin treatment, must have had clinical be... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 20.0-65.0, Metabolic Syndrome Age between 20 and 65 years Metabolic syndrome by IDF 2005 known diabetes obesity due to endocrinologic disorders Psychological disorder or using psychological medications Abnormal liver function (three-fold upper normal limit) Abnormal renal function (1.5-fold upp... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-85.0, Mitral Valve Insufficiency Signed and dated the Patient Informed Consent (PIC) Indicated to have a surgical repair for a given degree of moderate to severe mitral valve regurgitation Willing to return to the implanting hospital for a 9 month follow-up visit Unwilling or inability to ... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 3.0-999.0, Hypochondroplasia Male or female children with hypochondroplasia defined by a disproportional short limb height and a X-ray evidence of shortening of the long bones and failure of increase in the interpedicular distance between lumbar vertebrae L1 and L5 Result of genetic analysis for... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 5.0-60.0, Marfan Syndrome Subjects must conform to the diagnostic Marfan syndrome according to the Ghent Criteria. 2. Outpatient subjects. 3. Male or female, aged between 5 and 60 years. 4. Women who are in a childbearing age are required a result of negative Gonadotropin pregnancy test to be in... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 19.0-75.0, Myocardial Infarction Mitral Regurgitation Patients who have undergone PCI for first acute MI (index MI) since 7/1/09 at MMC and STJ documented moderate mitral regurgitation on follow up echocardiography six or more weeks after PCI procedure English speaking CABG after PCI for acute ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Revision Total Knee Replacement Revision knees with bone defect for which metaphyseal sleeve in femoral and/or tibial side is used 2. Cases with at least 2 year follow-up 3. Cases with regular follow-up visits completed Cemented sleeves 2. Patients with less than two year follow-up ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 20.0-999.0, Stomach Ulcer patients underwent ESD for gastric adenoma or cancer subjects with previous gastric surgery subjects taking aspirin, anticoagulant, or antiplatelet agent subjects having malignancy except gastric cancer pregnant or breast-feeding women | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Mitral Valve Insufficiency Atrial Fibrillation Heart Failure Patients with severe mitral regurgitation are admitted for surgical intervention and are willing to participate in this study Presence of mitral stenosis More than mild severity of aortic valvular problem Any abnormality of... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Procalcitonin Coronary Artery Bypass Grafting Elective CABG + / Aortic / Mitral valve patients Off pump and on pump cases Check any box that applies: Patients with recent infection in last week and / or Antibiotics in last 1 week or pre op fever > 99.5f / 38C in 24hrs prior to surge... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Aortic Valve Disease Patients > or = to 18 years of age Presenting with aortic stenosis and to undergo elective aortic valve replacement or repair with or without aortic aneurysm dilation repair Able to sign informed consent document Patients unable to provide informed consent for a... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Pulmonary Arterial Hypertension HIV Infection Congenital Heart Defect Systemic Sclerosis Connective Tissue Disease age over 18 for PAH patients: pre-capillary PAH evidenced by right-heart catheterization no associated systemic disease for idiopathic PAH patients for HIV patients, HIV... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Mitral Regurgitation Patient is at least 18 years of age Patients with moderate-to-severe or severe functional MR EROA > 40 mm2 and an MR/LA > 40% (severe) ≤ EROA ≤ 40 mm2 and 30 ≤ MR/LA ≤ 40% (moderate-to-severe) Baseline rates of 50-90 beats per minute (patients with sinus rhythm) ... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 21.0-67.0, Tricuspid Valve Regurgitation Significant disorders in aortic and mitral valves Moderate ~ severe tricuspid regurgitation Underwent tricuspid repair or replacement operation Isolate tricuspid valve lesion Mild tricuspid valve regurgitation Tricuspid valve regurgitation was left witho... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Cardiac Surgery Tricuspid Valve Regurgitation All patients 18-65 + older years undergoing mitral valve surgery. 2. Presence of moderate or mild-moderate tricuspid regurgitation as read on any echocardiographic study performed within 6 months prior to operation. Assessment if tricuspi... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-85.0, Heart Valve Disease Coronary Artery Disease Willing and able to provide written informed consent Age >17 and < 86 years Patients undergoing planned cardiopulmonary bypass (CPB) for: 1. combined coronary artery bypass grafting and valve replacement/repair surgery 2. single valve replac... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 16.0-60.0, Marfan Syndrome Ages 16-60 years old with no treatment or β-blocker or other monotherapy only for Marfan syndrome Previous aortic dissection or aortic surgery Severe valvular regurgitation Aortic diameter at the sinotubular junction ≥ 5.0cm Contraindications to specific drug treatmen... | 1 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 18.0-999.0, Gestational Diabetes Gestational Hypertension Tricare Insurance Beneficiary (military insurance) receiving care at Nellis AFB Pregnant females (DoD beneficiaries) at least 18 years of age Diagnosed as being diabetic Diagnosed with chronic hypertension prior to pregnancy Personal or ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 65.0-999.0, Anti-coagulation Therapy DVT Pulmonary Embolism Joint Surgery Multiple Atrial Fibrillation Prosthetic Replacement of Mitral Valve Men and women at least 65 years old 2. Beginning warfarin (0 doses of warfarin taken at the time of enrollment) for a variety of diseases or conditions th... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.0-999.0, Marfan Syndrome Turner Syndrome Ehlers-Danlos Syndrome Loeys-Dietz Syndrome FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation Bicuspid Aortic Valve Without Known Family History Bicuspid Aortic Valve With Family History Bicuspid Aortic Valve With Coarctation Familial Thoracic Aorti... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 21.0-999.0, Aortic Stenosis Disorder of Prosthetic Cardiac Valve Aortic Valve Insufficiency Mitral Valve Insufficiency Hypertrophic Cardiomyopathy Tricuspid Valve Insufficiency patients with mild, moderate, or severe aortic stenosis or aortic or mitral prosthesis. Patients with aortic or mitral ... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 20.0-75.0, Gastroesophageal Reflux Disease Heartburn Patients with age of 20-75 years old (inclusive) in Taiwan of both genders Out-patients who had been diagnosed as non-erosive gastroesophageal reflux disease (NERD) Patients with heartburn or regurgitation (either one) as main symptom at least... | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.5-24.0, Marfan Syndrome Individual with Marfan syndrome consented in to the Main Atenolol Vs. Losartan NIH study Subjects in the main PHN Marfan trial who have not achieved the maintenance drug dosing or who have stopped taking study drug | 2 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 30.0-75.0, Mitral Valve Insufficiency Patient is a male or female between 30 to 75 years of age (inclusive) on the day of signing the informed consent Patients with a verified diagnosis of CAD, including post myocardial infarction scar Coronary artery pathology to be coronary artery bypasses gra... | 0 |
34 year old woman with Marfan's syndrome and known severe mitral valve prolapse with regurgitation, who was planned for a MV repair but was lost to follow-up. She remains symptomatic and is now prepared to undergo mitral valve repair/replacement surgery. EF of 65% on TTE. Past Medical History: Marfans Syndrome MVP with... | eligible ages (years): 0.5-18.0, Nephrotic Syndrome Age > 6 months and< 18 years 2. Idiopathic nephrotic syndrome 3. Ethical committee approval Age < 6 months or > 18 years 2. Congenital nephrotic syndrome 3. Secondary nephrotic syndrome (post-infectious, SLE, Schonlein-Henoch) defined by clinical features, low C3 an... | 0 |
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