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<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : diabetes mellitus ( dm ) has emerged as one of the major global health problems and a heavy burden for all healthcare systems . current prediction...
### Summary: : diabetic nephropathy ( dn ) is one of the major complications of diabetes mellitus ( dm ) , leads to chronic kidney disease ( ckd ) , and , ultimately , is the main cause for end - stage kidney disease ( eskd ) . beyond urinary albumin , no reliable biomarkers are available for accurate early diagnosti...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pyloric stenosis ( ps ) is one of the most common surgical conditions affecting infants with an incidence of approximately 0.9%5.1% per 1,000 live b...
### Summary: : backgroundduring the perioperative care of infants with hypertrophic pyloric stenosis , an opioid - sparing technique is often advocated due to concerns such as postoperative hypoventilation and apnea . although the rectal administration of acetaminophen is commonly employed , an intravenous ( iv ) p...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in late august 2003 , local , state , and federal health officials began an investigation to determine the risk factors associated with an outbreak ...
### Summary: : in august 2003 , a communitywide outbreak of cryptosporidiosis occurred in kansas . we conducted a case - control study to assess risk factors associated with cryptosporidium infection by using the telephone survey infrastructure of the behavioral risk factor surveillance system . using existing st...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the internal globus pallidus ( gpi ) and substantia nigra pars reticulata ( snr ) are the basal ganglia ( bg ) output nuclei . besides projecting to...
### Summary: : previous work has shown the functions associated with activation of dopamine presynaptic receptors in some substantia nigra pars reticulata ( snr ) afferents : ( i ) striatonigral terminals ( direct pathway ) posses presynaptic dopamine d1-class receptors whose action is to enhance inhibitory postsynap...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : though , the advantages of central venous catheter ( cvc ) placement outweigh the disadvantages significant risks are associated with the insertion ...
### Summary: : we report an uncommon complication of subclavian central venous catheterization , discovered at thoracotomy . the central venous catheter ( cvc ) was placed by left infraclavicular route after induction of general anesthesia . cvc was secured after aspiration of blood and satisfactory central venou...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : vascular endothelial growth factor ( vegf ) and its receptors are thought to play a pivotal role in tumor angiogenesis . bevacizumab is a humanize...
### Summary: : background . randomized studies have shown different magnitude of bevacizumab benefit in the treatment of advanced breast cancer . regulatory agencies have modified bevacizumab treatment indications across different regions . in this study , we perform a meta - analysis of phase iii studies aimin...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in a remarkable number of patients suffering from low back pain ( lbp ) , a specific physiological or structural abnormality can not be found . al...
### Summary: : in the current study , the overall prevalence and the main underlying etiologies of inflammatory low back pain ( ilbp ) were determined , and the effectiveness of treatment with sulfasalazine was investigated in patients with inflammatory versus mechanical low back pain ( lbp ) . in a prospective study...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : achalasia cardia is a primary motility disorder of the esophagus characterized by aperistalsis of the body of the esophagus and failure of relaxatio...
### Summary: : achalasia cardia is a neuromuscular disorder of unknown etiology involving the body of the esophagus and lower esophageal sphincter ( les ) . it is characterized by aperistalsis of the body of the esophagus and failure of relaxation of lower esophageal sphincter . it usually affects patients betwee...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : three - dimensional ( 3d ) computer reconstruction of a target volume or of a surface is an important activity in modern biomedical imaging . th...
### Summary: : determining the outline or boundary contour of a two - dimensional object , or the surface of a three - dimensional object poses difficulties particularly when there is substantial measurement noise or uncertainty . by adapting the mathematical approach of stochastic function recovery to this task ,...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in a recent article for critical care link and colleagues reported that the reversible platelet glycoprotein iib / iiia antagonist tirofiban may pre...
### Summary: : link and colleagues present a pilot study investigating platelet function and platelet numbers in patients with cardiogenic shock and acute kidney failure undergoing continuous venovenous haemodialysis . their data indicate a significantly reduced platelet loss with combined therapy of unfractionated...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : children and adolescents with gerd usually have a history of vomiting and spitting up as an infant . if gerd is left untreated , it can lead to ...
### Summary: : backgroundgastroesophageal reflux disease ( gerd ) is a common problem seen in pediatrics and adolescents . the bravo ph monitoring system is a capsule that detects and quantifies the severity of reflux disease . this test is also valuable for evaluation of patients with extra - gastrointestinal ma...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : muscle fatigue involved in inspiration , such as diaphragm muscle , external intercostal muscle , or parasternal intercostal muscle , induces a sh...
### Summary: : [ purpose ] the purpose of the present study was to evaluate the effect of water immersion at different water depths on respiratory function and the effect of inspiratory load breathing ( ilb ) during water immersion at different water depths on respiratory muscle strength evaluated by maximum in...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the underwater environment produces some pathophysiological problems due to the fast changing of its bounded pressure which may cause various illnes...
### Summary: : background : there is not any data available about the effect of high bar pressure condition on intracranial pressure . in this study , the effect of diving on the optic nerve and sheath diameters as non - invasive markers of intracranial pressure has been investigated . methods : twenty profession...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : it is usually controlled by cis - acting factors , such as au - rich elements ( ares ) in the 3utr , and transacting factors , such as rna - binding...
### Summary: : uu and ua dinucleotides are rare in mammalian genes and may offer natural selection against endoribonuclease - mediated mrna decay . this study hypothesized that reducing uu and ua ( uw ) dinucleotides in the mrna - coding sequence , including the codons and the dicodon boundaries , may promote resis...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : patients fulfilling criteria for ftd were consecutively recruited from the centre for aging brain and neurodegenerative disorders , university of br...
### Summary: : objective : in this study , we evaluated whether variations within genes specifically associated with dyslexia , namely kiaa0319 , dcdc2 , and cntnap2 , were associated with greater damage of language - related regions in patients with frontotemporal dementia ( ftd ) and primary progressive aphasia ( p...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : small cell carcinoma is a malignancy that occurs mainly in the lung , and primary lesions in the head and neck are very rare . extrapulmonary smal...
### Summary: : we report a rare case of extrapulmonary small cell carcinoma arising in the palatine tonsil treated by combined chemotherapy with irinotecan / cisplatin following irradiation therapy . this chemotherapy regimen was recently found to be effective for small cell lung carcinoma . our case is the first...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hiv is a preventable chronic , life - threatening illness affecting fetal and maternal health , increasing both morbidity and mortality in both infe...
### Summary: : recent studies suggest that acquisition of hiv-1 infection during pregnancy and breastfeeding is associated with a high risk of hiv mother - to - child transmission . this study evaluates risk factors associated with hiv acquisition during pregnancy in women delivering at a large metropolitan medical...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : home care is a rapidly expanding and evolving industry . as levit and her colleagues highlight , home health is the fastest growing component of med...
### Summary: : this overview discusses articles published in this issue of the health care financing review , entitled issues in reforming home health care . articles focus on basic policy issues in the financing and delivery of home care services , illustrate how research provides insights into these issues , and...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : ovarian cancer is the most lethal gynecologic malignancy among women , with an estimated 150 000 annual deaths worldwide . however , due to the un...
### Summary: : backgroundadiponectin receptor-1 ( adipor1 ) has been reported to be associated with the risk of obesity - associated malignancies , including epithelial ovarian cancer ( eoc ) . the aim of this study was to determine if adipor1 could serve as a prognosis indicator for patients with eoc.material/meth...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : male sd rats ( simonsen laboratories , gilroy , ca ) were housed individually and maintained on a 12-h light / dark cycle ( lights on at 0600 h ) wi...
### Summary: : objectiveto examine the role of amp - activated protein kinase ( ampk ) in the control of glucoprivic feeding by hindbrain catecholamine neurons.research design and methodsmicropunched hindbrain samples were collected from control and 2-deoxy - d - glucose ( 2dg)-injected rats for western blot analysis...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : reports have described the increasing use of endoscopic ultrasound - guided hepaticogastrostomy ( eus - hg ) to treat malignant biliary obstruction ...
### Summary: : background and study aims : an iincreasing number of reports describe endoscopic ultrasound - guided hepaticogastrostomy for malignant biliary obstruction in patients with endoscopic retrograde cholangiopancreatography failure . however , this procedure has not yet been standardized ; as a result , t...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : consumer - directed healthcare ( cdhc ) is center stage in health policy debates . many politicians and corporate leaders hope that high deductible ...
### Summary: : many politicians and business leaders are advocating high deductible health insurance plans linked with health savings accounts so - called consumer - directed healthcare . these policies penalize the sick , discourage needed care ( especially primary and preventive care ) , and direct tax subsidies...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic recurrent multifocal osteomyelitis ( crmo ) , a disorder that primarily affects children and adolescents , is characterized by episodic osse...
### Summary: : abstractan 11-year - old boy was diagnosed with chronic recurrent multifocal osteomyelitis ( crmo ) and presented with right sacro - femoral and occipital lesions . initially , a tumor was suspected . however , the bone biopsy showed osteomyelitis with a negative bacterial culture . bone scintigrap...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the increasing number of road traffic accidents in our country has made it extremely difficult to analyze the exact reported incidence of mortality ...
### Summary: : background and objectives : maxillofacial trauma is commonly associated with other injuries , predominantly head injuries . the predictors of outcome in such concomitant injuries have been studied the least . the present study aims at the evaluation of types of injury , management and outcome of pa...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : we developed and followed a standardized protocol to do this meta - analysis in accordance with the preferred reporting items for systematic reviews...
### Summary: : backgroundguidelines recommend exercise for cardiovascular health , although evidence from trials linking exercise to cardiovascular health through intermediate biomarkers remains inconsistent . we performed a meta - analysis of randomized controlled trials to quantify the impact of exercise on cardi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : exercise physiology and the salutatory effects on weight loss , fat reduction , and insulin sensitivity have been described in great detail . thes...
### Summary: : we review the current concepts about energy expenditure and evaluate the physical activity ( pha ) in the context of this knowledge and the available literature . regular pha is correlated with low body weight and low body fat mass . the negative fat balance is probably secondary to this negative e...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: :
### Summary: : bovine ( bam ) and rat ( ram ) alveolar macrophages were incubated in vitro with dq12 quartz or uicc chrysotile asbestos either alone or in the presence of dipalmitoyl lecithin ( dpl ) . the reaction of the cells of both species to the untreated dust particles was similar qualitatively and quantitative...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : antigen - activated cd4 t cells differentiate into either th1 or th2 cells , producing proinflammatory or proallergic cytokines , respectively . t...
### Summary: : although interleukin ( il)-12 and il-4 polarize naive cd4 + t cells toward t helper cell type 1 ( th1 ) or th2 phenotypes , it is not known whether cytokines instruct the developmental fate in uncommitted progenitors or select for outgrowth of cells that have stochastically committed to a particular fa...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in the united states nearly 40,000 deaths are attributed to metastatic breast cancer ( mbc ) annually . once breast cancer has metastasized it is ...
### Summary: : circulating tumor cells ( ctcs ) were discovered nearly 150 years ago but have only recently been recognized as a feature of most solid tumors due to their extremely low concentration in the peripheral circulation . several technologies have been developed to isolate and analyze ctcs , which can now ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 56-year - old man was hospitalized because of pain and numbness in his left hand since he slipped a week earlier . , we found that the motor and...
### Summary: : floating thrombi in the aortic arch are very rare and an unusual source of systemic embolism . herein , a case of a 3-cm thrombus in the aortic arch is reported . it was a floating , highly mobile thrombus attached to the lesser curvature of the aortic arch . the patients had a hypercoagulable diso...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 17-year - old healthy male was seen with complaints of painless swelling over the left eye for the past four weeks . the rest of the systemi...
### Summary: : rosai - dorfman disease is a rare idiopathic disorder characterized by painless lymphadenopathy with cervical involvement in more than 80% cases . we report a case of rosai - dorfman disease presenting as an isolated epibulbar mass in a healthy young adult male . epibulbar involvement in ro...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : idiopathic granulomatous mastitis ( igm ) is an uncommon disease which usually arises in premenopausal women shortly after their last childbirth . ...
### Summary: : granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis , sarcoidosis , foreign body reaction , and mycotic and parasitic infections . in contrast , idiopathic granulomatous mastitis ( igm ) is characterized by the presence of chronic g...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : scapular spine stress fractures are uncommon following cuff tear arthropathy , there are only six reported cases in the english literature . manag...
### Summary: : we report a case of bilateral scapular spine stress fracture , treated conservatively on one side and operatively on the other side . besides , we performed a literature review to establish management options . a 61-year - old right - handed gentleman came to our clinic with acute on chronic deterior...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pathways of gene silencing and small regulatory rnas such as mirnas ( micrornas ) and sirnas ( short interfering rnas ) are widespread in almost all...
### Summary: : argonaute protein family is the key players in pathways of gene silencing and small regulatory rnas in different organisms . argonaute proteins can bind small noncoding rnas and control protein synthesis , affect messenger rna stability , and even participate in the production of new forms of small r...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : preparation of hard tissues for the insertion of dental implants is usually performed by drilling at high - speed with irrigation . recently , a n...
### Summary: : objectivesin this study we evaluated heat generation during the low - speed drilling procedure without irrigation.materials and methodsten artificial bone blocks that were similar to human d1 bone were used in this study . the baseline temperature was 37.0. we drilled into 5 artificial bone blocks 60...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 66-year - old japanese woman was referred to us with a 6-month history of decreased vision and metamorphopsia in the left eye . visual acuity was ...
### Summary: : it has been reported that pulsations in abnormal vessels are observed on indocyanine green ( icg ) angiography in half of patients with polypoidal choroidal vasculopathy ( pcv ) , although the mechanism of the pulsation is unknown . in this study , we report a case of pcv showing venous pulsations at...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : autophagy is generally considered to be a cell survival mechanism and may also contribute to cell death , depending on its various biological contex...
### Summary: : the autophagic process involves encompassing damaged proteins and organelles within double- or multi - membraned structures and delivering these molecules to the lytic compartments of vacuoles . sphingolipids ( sls ) , which are ubiquitous membrane lipids in eukaryotes , participate in the generation...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth - supporting tissues . the progression of per...
### Summary: : objectives : statins are the group of lipid - lowering drugs commonly used to control cardiovascular and cerebrovascular diseases . statins have potential anti - inflammatory effect by blocking the intermediate metabolites of the mevalonate pathway . the objective of this study was to evaluate the ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : minimally invasive surgical ( mis ) total knee arthroplasty ( tka ) was developed to facilitate early and intermediate - term rehabilitation . ...
### Summary: : purposeprevious studies dealing with gait after minimally invasive surgery ( mis ) total knee arthroplasty ( tka ) are rare and insufficient . it was the purpose of the study to determine in a prospective , comparative setting whether mis influences the outcome of tka in terms of typical 3d gait para...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( cadasil ) is a systemic arteriopathy due to missense mu...
### Summary: : key clinical messagedespite transient global amnesia is considered unusual in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( cadasil ) and causal relation is still unclear , this report suggests to consider cadasil in those patients with recurrent transient...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : however , metastatic disease can arise in approximately 20%30% of patients and accounts for over 28,000 deaths a year in the united states.1 androge...
### Summary: : introductionenzalutamide is an oral androgen receptor ( ar ) signaling inhibitor that was specifically engineered to overcome castration - resistant prostate cancer ( crpc ) harboring ar amplification or overexpression . enzalutamide has demonstrated significant activity in men with metastatic crpc.a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : more than 50% of individuals with voice disorders have benign alterations of the vocal fold mucosa . polyps are one of the most frequent vocal cor...
### Summary: : summary introduction : dysphonia is the main symptom of lesions that affect the vocal tract . many of those lesions may require surgical treatment . polyps are one of the most common forms of vocal cord lesions and the most prevalent indication for laryngeal microsurgery . there are different type...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : irrigation has been recognized to have been playing a crucial role in addressing the central challenges caused by food insecurity and rainfall uncer...
### Summary: : assessment of soil erosion and sediment yield in furrow irrigation is limited in samaru - zaria . data was collected in 2009 and 2010 and was used to develop a dimensionless model for predicting furrow irrigation - induced erosion ( fiie ) using the dimensional analyses approach considering stream si...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : amalgam is a restorative material especially suitable for classes i and ii restorations in teeth that encounter heavy chewing forces . the advanta...
### Summary: : replacement of dental restorations has been the traditional treatment for defective restorations . this five - year prospective clinical trial evaluated amalgam restorations with localized defects that were treated by means of repair or refurbishing . fifty - two patients ( 50% female and 50% male ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : improvements in the mechanical properties of composite resins and esthetic needs have brought about an increase in the application of these material...
### Summary: : aim : to evaluate bond strength between rmgi and composite using different adhesive systems and curing techniques.materials and methods : sixty prepared samples of rmgi were randomly divided into six groups according to adhesive systems ( total - etch , two - step self - etch and all - in - one ) and c...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : advances in chemotherapy and radiotherapy have altered the natural course of disease in patients with systemic cancer , who now live longer than eve...
### Summary: : abstractprimary malignant tumours arising from the meninges are distinctly uncommon , and when they occur , they are usually sarcomas . in contrast , metastatic meningeal involvement is increasingly seen as advances in cancer therapy have changed the natural history of malignant disease and prolonged...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : g protein - coupled receptors ( gpcrs ) compose the largest family of membrane - bound receptors and many members still have unrevealed functions . ...
### Summary: : mas - related g - protein coupled receptor member d ( mrgprd ) is a g protein - coupled receptor ( gpcr ) which belongs to the mas - related gpcrs expressed in the dorsal root ganglia ( drg ) . in this study , we investigated two novel ligands in addition to beta - alanine : ( 1 ) beta - aminoisobutyri...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic infection with hepatitis b virus ( hbv ) results in an estimated 786 000 deaths annually worldwide 1 . infected individuals may remain as...
### Summary: : early identification of chronic hepatitis b is important for optimal disease management and prevention of transmission . cost and lack of access to commercial hepatitis b surface antigen ( hbsag ) immunoassays can compromise the effectiveness of hbv screening in resource - limited settings and among ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 68-year - old man initially presented with a one - month history of cough , heartburn , and episodes of nocturnal regurgitation . eight months p...
### Summary: : laparoscopic adjustable gastric banding ( lagb ) is an increasingly common therapeutic option in the management of obesity and certain obesity - related comorbid conditions . as it gains popularity for its advantages of being minimally invasive and reversible , clinicians should be aware of growing e...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : large scale trials with insecticide treated bed nets ( itns ) have been shown to have a profound impact on reducing malaria transmission in experime...
### Summary: : we studied the effect on malaria incidence , mosquito abundance , net efficacy , net use rate , chemical analysis , and holes of a long lasting insecticide treated bed net ( netprotect ) in western kenya , 20072010 . nets were hung in 150 households 6 months before they were hung in a second , 2 km ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : this lethal variant results from the inheritance of an autosomal recessive gene and causes abnormal development of cartilage and fibrous connective ...
### Summary: : fibrochondrogenesis is a rare , neonatally lethal osteochondrodysplasia , with autosomal recessive inheritance . it differs from other lethal dwarfisms in that it leads to broad , long - bone metaphyses ( dumb - bell shaped ) and pear - shaped vertebral bodies . we report a case of fibrochondrogene...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : matrix metalloproteinases ( mmps ) are zinc - dependent proteases that are involved not only in the degradation and remodeling of the extracellular ...
### Summary: : background : inflammatory processes could underlie mood disorders . matrix metalloproteinases ( mmps ) and tissue inhibitors of mmps ( timp ) are inflammation - related molecules . the current study sought an association between mood disorders and systemic levels of mmps and timps.methods:serum was o...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : acute subdural hemorrhage requires emergent neurosurgery or close observation because of its high mortality rate . a number of cases who showed ra...
### Summary: : acute subdural hematoma is usually a neurological emergency that requires hematoma evacuation or close observation . however , spontaneous resolutions of an acute subdural hematoma without surgical interventions have been reported rarely . we report on a case who showed rapid resolution of an acute...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the study was conducted in 3 communities in ghana : kwamang ( population 8,000 ) , forikrom ( population 3,800 ) , and buoyem ( population 3,900 ) ....
### Summary: : because some bats host viruses with zoonotic potential , we investigated human bat interactions in rural ghana during 20112012 . nearly half ( 46.6% ) of respondents regularly visited bat caves ; 37.4% had been bitten , scratched , or exposed to bat urine ; and 45.6% ate bat meat . human bat int...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in recent times in some occupations work in static sedentary postures for long hours in order to perform the tasks required of them . this can c...
### Summary: : [ purpose ] this study investigated the effects of forward head posture on forced vital capacity and deep breathing . [ subjects ] twenty - six subjects , divided into the two groups ( normal and forward head posture groups ) , participated in this study . [ methods ] forced vital capacity and ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : older adults with a range of comorbidities are often prescribed multiple medications , some of which may impact on their function and cognition , an...
### Summary: : backgroundolder adults with a range of comorbidities are often prescribed multiple medications , which may impact on their function and cognition and increase the potential for drug interactions and adverse events.aimsthis study investigated the extent of polypharmacy and potentially inappropriate medi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : oxidative stress tends to occur during the neonatal period because the younger the gestational age , the lower the antioxidant capacity ( ac ) and a...
### Summary: : this study aimed to consider the significance of breast milk in preventing oxidative stress by comparing total antioxidant capacity ( tac ) in breast milk and formula milk for premature infants , demonstrating the relationship between tac in breast milk and postnatal age in days . we used the biologi...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 42-year - old man with hcv was referred to our hospital in august 2004 because of diarrhea and bloody stool . ten years before admission , he ha...
### Summary: : a 42-year - old man with chronic hepatitis c and ulcerative colitis ( uc ) was referred to our hospital in august 2004 because of bloody diarrhea . he was clinically and endoscopically diagnosed with flare of uc . after informed consent had been obtained , he was treated with peg - ifn--2a . four...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : abdominopelvic fluid collection and abscess management and the outcomes have improved in the recent years due to innovation of the image - guided dr...
### Summary: : background : abdominopelvic fluid collection and abscess management and their outcomes have improved in the recent years due to innovation of the image - guided drainage technique and improvement of surgical proceduresobjectives : this study was undertaken to evaluate the efficacy of ct - guided percut...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : presentations at international scientific conferences such as ics and iuga are the most important route for early dissemination and discussion of re...
### Summary: : introductionthis article aims to condense the lectures and discussions from workshops on good reporting at iuga como 2009 and ics san francisco 2009 , providing practical advice for the novice researcher summarising their data for the first time.conclusionsdrafting an abstract can be a time consuming p...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : developmental dental disorders may be due to abnormalities in the differentiation of the dental lamina and the tooth germs ( anomalies in number , s...
### Summary: : geminated teeth are the consequences of developmental anomalies leading to the eruption of joined elements . according to current definitions , gemination occurs when one tooth bud tries to divide , while fusion occurs if two buds unite . clinical experience shows , however that diagnosis can be co...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : absorption , distribution , metabolism , and elimination ( adme ) studies in drug discovery have always played a critical role in optimizing the dr...
### Summary: : background : a rapid and comprehensive metabolic stability screen at the top of a drug discovery flow chart serves as an effective gate in eliminating low value compounds . this imparts a significant level of efficiency and saves valuable resources . while microsomes are amenable to high throughput a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : there is a growing interest in using propofol for sedation in endoscopic procedures.14 propofol is commonly used as an anesthetic agent in endoscopi...
### Summary: : introductionmoderate to deep sedation is generally used for endoscopic retrograde cholangiopancreatography ( ercp ) . the depth of sedation is usually judged by clinical assessment and electroencephalography - guided monitoring . the aim of this study was to compare the clinical efficacy of clinica...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : sinusoidal obstruction syndrome ( sos ) is a severe adverse event of long - term chemotherapy in patients with colorectal cancer . in contrast , i...
### Summary: : introductionsinusoidal obstruction syndrome ( sos ) is a severe adverse event of long - term chemotherapy in patients with colorectal cancer . it usually develops as liver congestion due to diffuse microscopic obstruction in liver parenchyma . in contrast , it sometimes appears as a liver mass occu...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : bladder cancer has a complex etiopathogenesis dependent on various factors : chemical carcinogens ( smoking , professional exposure : industry carci...
### Summary: : bladder cancer is one of the most commonly diagnosed malignancies worldwide , derived from the urothelium of the urinary bladder and defined by long asymptomatic and atypical clinical picture . its complex etiopathogenesis is dependent on numerous risk factors that can be divided into three distinct ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : tennis elbow ( te ) is not an inflammation of the outside portion of the elbow but rather is the degeneration of the extensor tendon of the humera...
### Summary: : [ purpose ] this study compared the analgesic effects of extracorporeal shock wave therapy with those of ultrasound therapy in patients with chronic tennis elbow . [ subjects ] fifty patients with tennis elbow were randomized to receive extracorporeal shock wave therapy or ultrasound therapy . [ ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chest pain accounts for approximately 56 million emergency department ( ed ) visits and 1 in every 50 outpatient visits in the united states , ultim...
### Summary: : the detection and quantification of coronary artery calcification ( cac ) significantly improves cardiovascular risk prediction in asymptomatic patients . many have advocated for expanded cac testing in symptomatic patients based on data demonstrating that the absence of quantifiable cac in patients ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a flow diagram of the algorithm is shown in figure 1 . to implement this procedure for a given model it is necessary to define bounds for inpu...
### Summary: : quantitative systems pharmacology models mechanistically describe a biological system and the effect of drug treatment on system behavior . because these models rarely are identifiable from the available data , the uncertainty in physiological parameters may be sampled to create alternative parameter...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in type 2 diabetes mellitus ( t2 dm ) , a prevalent disease characterized by chronic hyperglycemia , the function of -cells responsible for insulin ...
### Summary: : colesevelam s glucose - lowering mechanism of action is not completely understood . clinical trials of colesevelam suggest that its mechanism , and often adverse effects , differ from those of other oral antidiabetes drugs . colesevelam does not affect insulin sensitivity ( unlike thiazolidinedione...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: :
### Summary: : glaucoma surgery is ripe for innovation . in the last few years , there has been a substantial increase in the number of devices approaching commercialization . while not all that is new is necessarily good , the role of these devices in changing glaucoma surgery is equally important in terms of both...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : currently , the combined prevalence of overweight ( bmi , body mass index 25 kg / m ) and obesity ( bmi 30 kg / m ) , defined by the world heal...
### Summary: : the accumulation of excess body weight may have important health and disease consequences for persons with multiple sclerosis ( ms ) . this study examined the effect of weight status on mobility using a comprehensive set of mobility outcomes including ambulatory performance ( timed 25-foot walk , t25...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : nonalcoholic fatty liver disease ( nafld ) is a clinicopathological condition characterised by lipid deposition in the liver and is a common cause o...
### Summary: : aim . the present study was designed to evaluate the heart rate variability ( hrv ) in nonalcoholic fatty liver disease ( nafld ) and to assess the effect of grade of nafld and diabetic status on hrv . methods . this cross - sectional study included 75 subjects ( 25 nafld without diabetes , 25 na...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: :
### Summary: : it is known that male breast cancer is extremely rare and obesity is a strong risk factor of breast cancer in both male and female . in general , the prognosis in breast cancer in males is known to be very poor compared to that in females as it tends to be more advanced stage due to delayed initial dia...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : gastric cancer is the second leading cause of death due to malignancy worldwide and occurs most frequently in the age group of 5070 years [ 13 ] . ...
### Summary: : aim . the aim of this study was to see the clinical , pathological , and demographic profile of young patients with stomach carcinoma besides association with p53 . patients and methods . prospective study of young patients with stomach carcinoma from january 2005 to december 2009 . a total of 50...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although dualenergy xray absorptiometry ( dxa ) , computed tomography and magnetic resonance imaging ( mri ) are considered reference methods for id...
### Summary: : abstractas reference methods are not available for identifying low skeletal muscle mass in clinical practice , the european group on sarcopenia in older people the asian working group for sarcopenia and the international consensus for cancer cachexia guidelines accept bioelectrical impedance analysis (...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : neurons can release small molecule neurotransmitters very rapidly in part because synaptic vesicles are docked to the membrane at active zones . d...
### Summary: : docking to the plasma membrane prepares vesicles for rapid release . here , we describe a mechanism for dense core vesicle docking in neurons . in caenorhabditis elegans motor neurons , dense core vesicles dock at the plasma membrane but are excluded from active zones at synapses . we have found ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : previously , we hypothesized that the development of cognitive processes provided such endowed animals with an additional coping strategy in dealing...
### Summary: : cognitive ability did not appear de novo in humans . despite our ability to recognize limited cognitive behavioral characteristics in animals , there has been no outcry to proclaim this phenomenon . the notion that humans are the only animals to possess cognition has taken advantage of the illusory p...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : acute respiratory tract infections ( artis ) are a leading cause of morbidity and mortality in children worldwide[1 , 2 ] . many viruses are assoc...
### Summary: : objectivehuman metapneumovirus ( hmpv ) is a respiratory pathogen responsible for disease and subsequent hospitalizations in young children around the world . the disease pathology , including how viral load correlates with respiratory disease severity , remains unclear . this study investigated th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hepatitis c virus ( hcv ) infection is a major health problem that affects almost 3% of the world 's population with a morbidity and mortality rates...
### Summary: : background : gradual development of a useful vaccine can be the main point in the control and eradication of hepatitis c virus ( hcv ) infection . hepatitis c virus envelope glycoproteins are considered as the main hcv vaccine candidate.objectives:in this study , the pichia pastoris expression system...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cd36 is a multifunctional signalling molecule with several known ligands , including thrombospondin-1 , long chain fatty acids and both native and a...
### Summary: : objective : elevated plasma levels of the fatty acid transporter , cd36 , have been shown to constitute a novel biomarker for type 2 diabetes mellitus ( t2 dm ) . we recently reported such circulating cd36 to be entirely associated with cellular microparticles ( mps ) and aim here to determine the ab...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : cytomegalovirus ( cmv ) a viral pathogen of herpesviridae , can cause serious disease in immunecompromise patients such as solid organ transplant re...
### Summary: : background : cytomegalovirus ( cmv ) , a problematic virus in solid organ transplant recipients ( sotr ) such as liver , can worsen overall mortality and transplant outcome , so its prevention and treatment is a key of success in such patients . this study is aimed to compare the efficacy of ganciclo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the presence of pancreatic tissue outside its normal localization and without anatomic and vascular continuity with the normal pancreas is termed he...
### Summary: : a 9-year - old boy presented with duodenal pancreatic rest causing obstruction and required surgical intervention . he had been treated at the age of 4 months for a choledochal cyst . both choledochal cyst and heterotopic pancreas are entities that are commonly encountered in children , but the inc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : . the prediction of domains from sequence information can improve tertiary structure prediction ( 1 ) , enhance protein function annotation ( 2 ) , ...
### Summary: : protein domain prediction is important for protein structure prediction , structure determination , function annotation , mutagenesis analysis and protein engineering . here we describe an accurate protein domain prediction server ( domac ) combining both template - based and ab initio methods . th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : strauss syndrome , is a non - inheritable and nontransmissible disease affecting medium and small vessels . it is an autoimmune vasculitis leading...
### Summary: : eosinophilic granulomatosis with polyangiitis ( egpa ) is a rare , autoimmune small and medium vessel vasculitis . egpa is accompanied by asthma and involves mainly the blood vessels of the lungs , gastrointestinal system , and peripheral nerves ; however , the skin , kidneys , and heart may be also ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : diaphragmatic rupture is a very rare injury , which occurs in less than 2% of all blunt injuries to the abdominal area . injury to the diaphragm i...
### Summary: : right - sided traumatic diaphragmatic rupture in childhood is a very rare injury . diaphragmatic rupture often manifests itself later , after an organ progressively herniates into the pleural cavity . when the patient is tubed , the ventilation pressure does not allow herniation of an organ , which...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : irritable bowel syndrome ( ibs ) is traditionally diagnosed using the rome diagnostic criteria , a symptom - based criteria standard , currently rev...
### Summary: : traditionally , irritable bowel syndrome ( ibs ) has not been regarded as an organic disease , and the pathophysiology of ibs is heterogeneous . currently , the diagnosis of ibs is based upon the rome diagnostic criteria . the performance of these criteria is only modest in predicting ibs , and moreo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the most dreaded complication of kawasaki disease reported in the literature over the years is coronary artery disease , which is considered as the ...
### Summary: : backgroundkawasaki disease is an acute self - limiting vasculitis that affects children . the most dreaded complication of kawasaki disease reported in the literature over the years is coronary artery disease , which is considered as the main cause of acquired heart disease . however , pulmonary as...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : abomasum is one of the most important sites for nematodes , which could be harmful to the health of infected animal and causes economic losses due t...
### Summary: : background : genomic dna was isolated from parabronema skrjabini . rrna region was amplified and sequenced.methods:the rna secondary structure was predicted using mfold software ( http://mfold.rit.albany.edu ) . the secondary structure with bulge , hairpins , helices , interior , external and m...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : pu - erh tea is a special tea species in china and has become one of the most popular beverages in southwestern china and southeast asian , owing to...
### Summary: : a simutaneous distillation extraction ( sde ) combined gc method was constructed for determination of volatile flavor components in pu - erh tea samples . dichloromethane and ethyl decylate was employed as organic phase in sde and internal standard in determination , respectively . weakly polar db-...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the local inflammatory response and the anatomical features of the herniated disc and spinal canal determine the resultant clinical syndrome which m...
### Summary: : background : nucleoplasty ( percutaneous lumbar disc decompression ) is a minimally invasive procedure that utilizes radiofrequency energy as a treatment for symptomatic lumbar disc herniation , against open microdiscectomy , which would be the mainstay treatment modality . the literature reports a f...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although psa was once described as a variant of rheumatoid arthritis ( ra ) , it has been included in the group of spondyloarthropathies . psa was...
### Summary: : psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis . it is considered a unique arthropathy with distinct clinical and radiologic features . up to 40% of patients with psoriasis may develop psoriatic arthritis . psoriasis usually precedes psoriatic arthritis ,...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic obstructive pulmonary disease ( copd ) is a disabling disease , of which the prevalence increases with age and causes significant morbidity ...
### Summary: : purposechronic obstructive pulmonary disease ( copd ) is associated with increased postoperative complications . recently , the global initiative for chronic obstructive lung disease ( gold ) classified copd patients into four groups based on spirometry results and the severity of symptoms . the ob...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the prevalence of diabetes is increasing rapidly worldwide with the influence of expanding economy , abrupt transition of living styles , and social...
### Summary: : backgroundtype 2 diabetes is associated with acute and chronic complications and poses a large economic , social , and medical burden on patients and their families as well as society.objectivethis study aims to evaluate the direct economic burden of type 2 diabetes in china . data source : systemati...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : eccrine angiomatous hamartoma ( eah ) is a benign enlargement of eccrine components , accompanied by abundance of vascular channels . the anomaly ...
### Summary: : hamartomatous , circumscribed swellings of the extremities make an interesting study . presentations are manifold and the naevi are not always present from birth . excessive growth of hairs leads to remarkable appearance of such swellings . a young woman presented to the dermatology department , co...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : more time is required for extraction cases , such as for adult patients , which is a great concern and poses high risk of caries , external root...
### Summary: : objectivethe aims of this study were to compare different surgical approaches to rapid canine retraction by designing and selecting the most effective method of reducing resistance by a three - dimensional finite element analysis . material and methodsthree - dimensional finite element models of ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the burgeoning atrial fibrillation ( af ) epidemic which currently affects over five million americans is expected to reach a prevalence of nearly 1...
### Summary: : as the global burden of atrial fibrillation ( af ) and its attendant economic impact on the healthcare system surges , there is increasing interest in the secondary prevention of af with various therapies . of the several identified risk factors for af , obesity is an important contributor that may b...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : epidemiological data have demonstrated that low levels of highdensity lipoprotein cholesterol ( hdlc ) are a strong and independent predictor of car...
### Summary: : backgroundrecent data showed inconsistent association of highdensity lipoprotein cholesterol ( hdlc ) with cardiovascular risk in patients with different levels of lowdensity lipoprotein cholesterol ( ldlc ) or intensive statin therapy . this study sought to determine the relationship of hdlc with pe...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 45-year - old female visited the hospital with a palpable mass on the medial aspect of her thigh . the mass was observed by the patient 3 months...
### Summary: : myxoid liposarcoma is a subtype of liposarcoma . this specific subtype can be identified based on its characteristic histological and cytogenetical features . the tumor has a fusion transcript of the chop and tls genes , which is caused by t(12;16)(q13;p11 ) . most of the fusion transcripts that ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although medical progress including new imaging modalities and technical support has been widely gained , controversy still continues in management ...
### Summary: : objectivethe aim of the study was to evaluate clinical characteristics of ureteroceles particularly for diagnostic and treatment challenges.methodsdata about patients treated for ureterocele in the two hospital clinics during 1996- 2009 are retrospectively evaluated.findingsthere were 12 girls and 7 bo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : when recruited from the cytosol to the membrane , many signaling proteins are activated in response to binding lipid activators with their mem...
### Summary: : protein kinase c- ( pkc ) has been studied widely as a paradigm for conventional pkcs , with two c1 domains ( c1a and c1b ) being important for the regulation and function of the kinase . however , it is challenging to explore these domains in membrane - bound environments with either simul...