input
stringlengths
172
751k
output
stringlengths
222
4.36k
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the cancer cells are capable of avoiding apoptosis , a programmed suicide mechanism , which confers them the ability of limitless cell expansion.1 c...
### Summary: : backgroundthe glyoxalase system including two thiol - dependent enzymes , glyoxalase i ( glo - i ) and glyoxalase ii , plays an important role in a ubiquitous metabolic pathway involved in cellular detoxification of cytotoxic 2-oxoaldehydes . tumor cells have high glycolytic activity , leading to inc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : since the birth of chronic dialysis treatment almost 50 years ago , significant technological and medical advancements have influenced the way patie...
### Summary: : background . there is little evidence for superior outcome of one dialysis therapy versus another . still , nephrologists have to prescribe dialysis every day . it is therefore of interest to ascertain the opinion among nephrology professionals regarding which therapy they consider to be the best a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: :
### Summary: : thyroid follicular cell tumors arise in rodents from mutations , perturbations of thyroid and pituitary hormone status with increased stimulation of thyroid cell growth by thyroid - stimulating hormone ( tsh ) , or a combination of the two . the only known human thyroid carcinogen is ionizing radiati...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the use of light cure composites for adhesion of orthodontic brackets to the enamel surface has been common in the past decades . these systems ca...
### Summary: : background : reduced time and appropriate bond strength of brackets is one of the most important aspects of orthodontic treatments . prolonged halogen light curing for bonding of brackets is undesirable , so the purpose of this study was to compare the shear bond strength of brackets bonded with halo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : aptamers are in vitro selected nucleic acid molecules that bind to a broad range of targets with high affinity and specificity . the basic isolation...
### Summary: : aptamers generated from randomized libraries of nucleic acids have found utility in a wide variety of fields and in the clinic . aptamers can be used to target both intracellular and extracellular components , including small molecules , proteins , cells , and viruses . with recent technological deve...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : calciphylaxis is a rare , but life - threatening disease characterized by progressive cutaneous necrosis and ulceration secondary to small- and medi...
### Summary: : calciphylaxis is a vascular calcification - cutaneous necrosis syndrome , usually seen in patients with end - stage renal disease and secondary hyperparathyroidism . we report a 57-year - old polyneuropathy , organomegaly , endocrinopathy , monoclonal gammopathy , and skin changes ( poems ) syndrome ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : idiopathic normal pressure hydrocephalus ( inph ) is an adult - onset syndrome of uncertain origin involving nonobstructive enlargement of the cereb...
### Summary: : the cerebrospinal fluid tap test ( csftt ) is recommended as a key step in the diagnosis of idiopathic normal pressure hydrocephalus ( inph ) . while there is no generally accepted evaluation period for ascertaining a csftt responder , a substantial number of patients are evaluated only once within 2...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the jugular foramen is a bony canal in the posterior cranial fossa , located between the temporal and occipital bones at the posterior end of the pe...
### Summary: : introduction : tumors affecting structures in the vicinity of jugular foramen such as glomus jugulare require microsurgical approach to access this region . these tumors tend to alter the normal architecture of the jugular foramen by invading it . therefore , it is not feasible to have correct anat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : trigeminal neuralgia ( tn ) is a paroxysmal shock - like pain restricted to the innervation area of one or more trigeminal branches , often set off ...
### Summary: : objectivesto investigate the clinical characteristics of patients with trigeminal neuralgia referred to surgery in a center of reference.methodswe evaluated the general characteristics of 395 patients with trigeminal neuralgia referred to neurosurgery as treatment . they corresponded to 2 samples of ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : worldwide , incidence rates of cutaneous malignant melanoma are rising in the last decades and only are exceeded by female pulmonary cancer . the ...
### Summary: : background : the presence of noncutaneous neoplasms does not seem to increase the risk of cutaneous malignant melanoma ; however , it seems to be associated with the development of other hematological , brain , breast , uterine , and prostatic neoplasms . an ecological transversal study was conducted...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : of patients with advanced chronic obstructive pulmonary disease ( copd ) , approximately 94% report breathlessness and 40% report pain.1 in the pall...
### Summary: : backgroundfew studies have evaluated the associations between respiratory parameters and pain in chronic obstructive pulmonary disease ( copd ) . the purpose of this study is to evaluate the differences in respiratory parameters between copd patients who did and did not have pain.methodsin this cross...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : periodontitis is the most common adult chronic inflammatory disorder , which results in a consequence of the persistent systemic inflammatory respon...
### Summary: : we report here that the leptomeningeal cells transduce inflammatory signals from peripheral macrophages to brain - resident microglia in response to porphyromonas gingivalis ( p.g . ) lps . the expression of toll - like receptor 2 ( tlr2 ) , tlr4 , tnf- , and inducible no synthase was mainly detect...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : congenital cholesteatoma ( cc ) can occur in any part of the temporal bone and the commonest site being in the middle ear , most probably due to its...
### Summary: : congenital cholesteatoma ( cc ) rarely presents with luc 's abscess . as a result of widespread usage of antimicrobial agents , luc 's abscess is hardly encountered in current clinical practice . herein , we report a case of luc 's abscess as the first presenting symptom in a 5-year - old boy with ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : renal cell carcinoma ( rcc ) is the most common malignancy of human kidney and accounts for approximately 2% of adult malignancies . the von hippe...
### Summary: : von hippel - lindau ( vhl ) disease is an autosomal dominant hereditary cancer syndrome that predisposes to the development of a variety of benign and malignant tumors , especially cerebellar hemangioblastomas , retinal angiomas and clear - cell renal cell carcinomas ( rcc ) . we have identified of v...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : 2 ) . this behavior is unaltered by the addition of gdp or non - hydrolyzable gtp analogs . however , gg dimerizes when incubated with either gtp ...
### Summary: : dynamin is an atypical gtpase that catalyzes membrane fission during clathrin - mediated endocytosis . the mechanisms of dynamin s basal and assembly - stimulated gtp hydrolysis are unknown , though both are indirectly influenced by the gtpase effector domain ( ged ) . here we present the 2.0 resol...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a persistent observation in the current field of human genetics is that single nucleotide polymorphisms ( snps ) identified through genome - wide as...
### Summary: : genome - wide association studies ( gwas ) have identified a multitude of single nucleotide polymorphisms ( snps ) associated with a wide spectrum of human phenotypic traits . however , the snps identified so far do not explain much of the expected genetic variation and they are poor predictors of th...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : for many years , removable complete dentures have represented the main solution for restoration of fully edentulous patients [ 13 ] . although many ...
### Summary: : purpose . nowadays , the advancements in direct metal laser sintering ( dmls ) technology allow the fabrication of titanium dental implants . the aim of this study was to evaluate implant survival , complications , and peri - implant marginal bone loss of dmls implants used to support bar - retained ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the amino acid products of endogenous and exogenous protein digestion are degraded by hepatic transamination and oxidative deamination to produce am...
### Summary: : ornithine carbamoyltransferase ( otc ) deficiency is a urea cycle disorder that causes the accumulation of ammonia , which can lead to encephalopathy . adults presenting with hyperammonemia who are subsequently diagnosed with urea cycle disorders are rare . herein , we report a case of a late - onset...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : fungal keratitis is a frequent cause of microbial keratitis in india.1 aspergillus and fusarium are two of the most common pathogenic fungi isolat...
### Summary: : to describe a case of alternaria keratitis in a 30-year - old male patient who presented with bilateral vascularised central corneal opacity and underwent deep anterior lamellar keratoplasty ( dalk ) in the left eye . patient was treated for recurrent epithelial defect with a bandage contact lens in ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : intraductal papillary mucinous neoplasms ( ipmn ) are pancreatic precancerous lesions composed of dilated main and branch ducts and mixed duct type ...
### Summary: : this study has analyzed the gene expression patterns of an ipmn microarray dataset including normal pancreatic ductal tissue ( nt ) , intraductal papillary mucinous adenoma ( ipma ) , intraductal papillary mucinous carcinoma ( ipmc ) , and invasive ductal carcinoma ( idc ) samples . and eight cluster...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : in saudi arabia , the basic law of governance states that the state shall look after public health and provide health care for every citizen . acc...
### Summary: : objectives : to assess the level of physicians ' knowledge about the contents of patients ' bill of rights ( pbr ) and its implementation.materials and methods : this cross - sectional study was carried out at a university hospital in the eastern province of saudi arabia . all physicians working in t...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : systemic lupus erythematosus ( sle ) is an autoimmune disease , which is characterized by tissue deposition of circulating immune complexes leading ...
### Summary: : lupus nephritis , which has various histological patterns and variable clinical outcomes , is one of the most important complications of systemic lupus nephritis ( sle ) . this pathogenetic mechanism in each histologically different type of lupus nephritis ( ln ) remains unclear . although sle is s...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : thirty - eight consecutive patients ( for a total of 41 eyes ) with pathologic myopia and subfoveal cnv who were treated with verteporfin ( visudyne...
### Summary: : purposeto determine the influence of clinical features and indocyanine green ( icg ) angiographic features on the visual outcome of patients with myopic sub - foveal choroidal neovascularization ( cnv ) who received photodynamic therapy ( pdt).methodsthirty - six consecutive patients ( 39 eyes ) with m...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : emphysematous pyelonephritis is a rare but life threatening necrotizing infection of the kidney caused by gas - forming bacteria . patients usuall...
### Summary: : emphysematous pyelonephritis ( ep ) is a rare , severe gas forming infection of renal parenchyma and its surrounding areas and potentially life threatening condition that requires prompt evaluation and treatment . although it commonly present with a fulminant clinical picture of sepsis , relatively m...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the age range of 6 to 15 years corresponds to a very sensitive period of life when children start going to school and discover themselves and have e...
### Summary: : introduction : we performed an analytic and prospective study over a period of 12 months from january 2nd to december 31st , 2008 , at the gynaeco - obstetric and paediatric hospital of yaound , cameroon . our aim was to determine the prevalence and causes of unilateral blindness in school children a...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : multiple myeloma ( mm ) is a mature b - cell malignancy which accounts for 13% of all hematologic malignancies in whites and 33% in blacks . it is...
### Summary: : abstractbackground : neuropathy is a common adverse effect of bortezomib . isolated central nervous system ( cns ) relapse in mm remains exceedingly rare and carries a dismal prognosis . we present an unusual case of bortezomib related neuropathy masking a cns relapse of mm . case presentation : a ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : dental trauma among young people represents a widespread clinical and dental public health problem.1 among children younger than 6 , 18% of all soma...
### Summary: : objectives : the aim of the present study was to evaluate the type and prevalence of primary tooth injuries , as well as their treatment and treatment outcomes , among children referred to the department of pedodontics at the ankara university faculty of dentistry in turkey.methods:the study population...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the simultaneous measurement of expression levels of tens of thousands of genes in a biological sample enabled by dna microarray technology has ...
### Summary: : genome - wide gene expression profile studies encompass increasingly large number of samples , posing a challenge to their presentation and interpretation without losing the notion that each transcriptome constitutes a complex biological entity . much like pathologists who visually analyze informatio...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : brain abscesses results from a focal suppurative process within the brain parenchyma , and brain abscesses account for 1 - 8% of all intracranial sp...
### Summary: : brain abscesses can be highly lethal if appropriate treatment is not administered , and reports of such an abscess caused by enterococcus avium are very rare . here , we report a case of a 48-year - old man presenting with chronic otitis media . he initially presented with a headache and right otal...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : one of the most common mechanical problems in implant prostheses is the joint loosening and fracture that occur in the screw joint portion between t...
### Summary: : purposethis study was conducted to evaluate the influence of the implant - abutment connection design and diameter on the screw joint stability.materials and methodsregular and wide - diameter implant systems with three different joint connection designs : an external butt joint , a one - stage interna...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the net effect of alcohol consumption on health is detrimental , with an estimated 3.8% of all global deaths and 4.6% of global disability - adjuste...
### Summary: : backgroundiran has one of the lowest alcoholic beverage use rates in comparison with other countries , because it is legally forbidden and because of religious beliefs . even so , unrecorded and noncommercial alcohol remains a considerable concern , which needs special attention.objectivesin the curr...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : although acute kidney injury ( aki ) is extremely common - with an incidence of about 2,100 per million population , similar to that of acute myoc...
### Summary: : kashani and colleagues studied two novel markers , insulin - like growth factor - binding protein 7 and tissue inhibitor of metalloproteinases-2 , in the urine of patients at high risk of acute kidney injury ( aki ) . they validated these markers in a separate large multicenter study and compar...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : we report the outcome of 2 patients of neglected hip dislocation which were treated by open reduction and internal fixation by k - wires . we trea...
### Summary: : introduction : traumatic dislocation of the hip in children is a rare injury . we report the outcome of 2 patients of neglected hip dislocation which were treated by open reduction and internal fixation by k-wires.case report : we treat 2 children both girls ( one was of 4 years and other was 7 years o...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the detection of specific macromolecules ( e.g. , protein antigens ) remains an important concern in the fields of human and animal health diagnosti...
### Summary: : a simple dot blot immunoenzymatic assay system was developed using polyester cloth coated with an oligo - dna aptamer to provide a high - affinity macroporous surface for the efficient capture of a model protein analyte ( thrombin ) in complex sample matrices such as foods . bound thrombin was detect...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : human parvovirus b19 is a ubiquitous infectious agent known to cause erythema infectiosum in children , bone marrow suppression and chronic anemia i...
### Summary: : a clinical association between idiopathic liver disease and parvovirus b19 infection has been observed . fulminant liver failure , not associated with other liver - tropic viruses , has been attributed to b19 in numerous reports , suggesting a possible role for b19 components in the extensive hepatoc...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 32-year - old man from thailand was referred to the emergency department of hadassah hebrew university hospital at mount scopus on july 31 , 2008...
### Summary: : in 2008 , melioidosis was diagnosed in an agricultural worker from thailand in the southern jordan valley in israel . he had newly diagnosed diabetes mellitus , fever , multiple abscesses , and osteomyelitis . burkholderia pseudomallei was isolated from urine and blood . four of 10 laboratory staff...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : residents living in the surrounding area of a large steel plant located near the dutch town of ijmuiden have been concerned about health effects fro...
### Summary: : we studied the spatial distribution of cancer incidence rates around a large steel plant and its association with historical exposure . the study population was close to 600,000 . the incidence data was collected for 19952006 . from historical emission data the air pollution concentrations for poly...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : intra - articular adhesion after knee surgery is a common and serious complication and is a challenge problem for orthopedic surgeons . the format...
### Summary: : backgroundintra - articular adhesion after knee surgery is a common and serious complication that presents a challenging problem for orthopedic surgeons . verapamil ( vp ) , a widely used calcium channel blocker , has been shown to prevent synthesis / secretion of extracellular matrix molecules . t...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : this is a normal protective mechanism associated with any lesion anywhere in the body . usually the patients complain of a localized pain in the...
### Summary: : infectious keratitis is a fairly common entity in india . however while paying attention to the primary entity , the associated events may be overlooked . enhanced pain usually suggests a worsening of the condition or development of associated problems like secondary glaucoma . however , cont...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : traumatic spinal cord injury ( sci ) is a complex , life - disrupting medical condition due to the detrimental effects on social , familiar , and pe...
### Summary: : spinal cord injury results in a life - disrupting series of deleterious interconnected mechanisms encompassed by the primary and secondary injury . these events are mediated by the upregulation of genes with roles in inflammation , transcription , and signaling proteins . in particular , cytokines ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : restoration of neutral mechanical alignment of the lower limb in total knee arthroplasty ( tka ) has been demonstrated as a key determinant of the l...
### Summary: : purposein total knee arthroplasty ( tka ) , it is important to restore neutral mechanical alignment . the purpose of this study was to assess whether the lower limb alignment is neutral in healthy korean females and investigate the incidence of constitutional varus knees among them.materials and meth...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : altered membrane permeability is a hallmark of inflammation and incipient ischemia , as demonstrated by experimental , radiologic , and pathologic s...
### Summary: : altered membrane permeability is a hallmark of inflammation and ischemia with systemic spreading . renal dysfunction is a risk factor for cardiovascular , cerebrovascular , and metabolic diseases . the aim of the present study was to assess proteinuria and urinary polyclonal light chains in acute s...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hypothyroidism is a relatively common problem worldwide often with insidious onset and is relatively asymptomatic . it is divided in two stages : ...
### Summary: : backgroundhypoventilation is a frequently suspected complication of hypothyroidism.objectivein this study we examined the hypothesis that changes in alveolar ventilation , as measured by end - tidal carbon dioxide ( et - co2 ) , differ between patients with mild ( subclinical ) and overt ( clinical ) t...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chylothorax is an infrequent but a serious complication of pediatric cardiovascular surgery and could often jeopardize postoperative recovery . th...
### Summary: : chylothorax is a serious complication of congenital cardiac surgery and is significantly associated with increased morbidity and mortality . central venous obstruction , which is often related to the insertion of central venous catheters for postoperative management , is known to be an important risk...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : acute kidney injury ( aki ) secondary to immersion and near - drowning is rarely described and poorly understood . much of the literature of near ...
### Summary: : acute kidney injury ( aki ) secondary to near - drowning is rarely described and poorly understood . only few cases of severe isolated aki resulting from near - drowning exist in the literature . we report a case of near - drowning who developed to isolated aki due to acute tubular necrosis ( atn )...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : hypertension peculiar to pregnancy ( preeclampsia and gestational hypertension ) is a pregnancy specific syndrome characterized by reduced organ per...
### Summary: : aims and objectives . ( i ) to determine the predictive value of cerebrouterine ( cu ) ratio ( middle cerebral artery to uterine artery pulsatility index , mca / ut pi ) in assessing perinatal outcome among hypertensive disorders of pregnancy . ( ii ) to compare between cu ratio and cp ratio ( mca ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : leishmaniasis represents a wide spectrum of clinical manifestations , ranging from a self - healing cutaneous lesion to fatal visceral disease . i...
### Summary: : leishmania antigens are weak immunogens and need to be potentiated by various adjuvants and delivery systems . alginate microspheres as antigen delivery system and quillaja saponins ( qs ) as immunoadjuvant have been used to enhance the immune response against autoclaved leishmania major ( alm ) . ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : acute eosinophilic myopericarditis ( aem ) is a rare disorder of unknown etiology , which is characterized by diffuse or focal myocardial inflammati...
### Summary: : we report a case of early non - invasive diagnosis of acute eosinophilic myopericarditis ( aem ) by cardiovascular magnetic resonance ( cmr ) before cardiac biopsy . a 35-yr - old woman presented with a flu - like illness , followed by pleuritic chest pain and shortness of breath . transthoracic echo...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic myeloid leukemia ( cml ) is a myeloproliferative disorder that results from the reciprocal translocation of the abl1 oncogene on chromosome ...
### Summary: : chronic myeloid leukemia ( cml ) is a clonal hematopoietic disorder characterized by the presence of the philadelphia chromosome which resulted from the reciprocal translocation between chromosomes 9 and 22 . the pathogenesis of cml involves the constitutive activation of the bcr - abl tyrosine kinas...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : a 36-year - old 5-week postpartum woman presented to the emergency room with complaints of nausea and vomiting for 48 h. she also reported a 2-day h...
### Summary: : a 36 year - old 5 weeks postpartum lactating woman presented to the emergency room with severe nausea and vomiting for 48 hours . the patient was found to be in non - diabetic ketoacidosis with a serum ph 6.9 and a hco3 of < 5meq / l . this condition rapidly improved with the administration of intr...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : ramelteon ( tak-375 ; rozerem ) is a tricyclic synthetic analog of melatonin ( fig . it was approved by the united states food and drug administra...
### Summary: : ramelteon is a tricyclic synthetic analog of melatonin that acts specifically on mt1 and mt2 melatonin receptors . ramelteon is the first melatonin receptor agonist approved by the food and drug administration ( fda ) for the treatment of insomnia characterized by sleep onset difficulties . ramelte...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : arterial cannulation is often required during anesthesia and critical care and provides valuable hemodynamic information and convenient access to ar...
### Summary: : background : endothelial dysfunction associated with diabetes mellitus ( dm ) may influence arterial vasoreactivity after arterial stimulus , such as cannulation , and cause changes in diameter and blood flow . despite the frequent use of arterial cannulation during anesthesia and critical care , littl...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : chronic pelvic pain ( cpp ) is now widely acknowledged as a common problem with significant consequences for those diagnosed with this condition.1 a...
### Summary: : objectivechronic pelvic pain ( cpp ) is widely acknowledged as a common problem with significant consequences for those diagnosed with this condition . there is a lack of studies with good sample size that provide a comprehensive psychological profile of women presenting to specialist chronic pain cl...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : microbial keratitis ( mk ) is an ocular emergency that requires prompt and specific management to maximise visual outcome and preserve ocular integr...
### Summary: : background . the bacteria isolated from severe cases of keratitis and their antibiotic sensitivity are recognised to vary geographically and over time . objectives . to identify the most commonly isolated bacteria in keratitis cases admitted over a 24-month period to a public hospital in auckland , n...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : there is a large gap between our ability to collect data and our ability to interpret it . the challenge faced by today 's researchers is to devel...
### Summary: : the onto - tools suite is composed of an annotation database and six seamlessly integrated , web - accessible data mining tools : onto - express , onto - compare , onto - design , onto - translate , onto - miner and pathway - express . the onto - tools database has been expanded to include various ty...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the incorporation and widespread use of total mesorectal excision ( tme ) as the standard mode of surgical resection of adenocarcinoma of the rectum...
### Summary: : the treatment of rectal cancer has evolved from being solely a surgical endeavor to a multidisciplinary practice . despite the improvement in outcomes conferred by the addition of chemoradiation therapy to rectal cancer treatment , advances in surgical technique have significantly increased rates of ...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : periodization of training workloads ( i.e. systematic variety in exercise frequency , intensity , duration , and mode over time ) is widely implemen...
### Summary: : energy ratings have been used as a marker of exercise readiness ( i.e. pre - exercise physical / mental state indicating ability to perform ) within flexible nonlinear periodization ( fnlp)-based resistance training interventions . however , empirical data is lacking regarding the utility of this app...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : only seven cases of necrotizing epiglottitis / supraglottitis have been reported in medical literature ; all in immunocompromised patients . the fea...
### Summary: : we report a case of an acute necrotizing supraglottitis in a healthy patient . only seven cases of necrotizing epiglottitis / supraglottitis have been reported in medical literature ; all in immunocompromised patients . the features and characteristics of necrotizing epiglottitis are discussed with r...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : the non - dystrophic myotonic syndromes are a set of disorders targeting skeletal muscles , characterized by muscle stiffness following contraction ...
### Summary: : the sodium channel blocker mexiletine is considered the first - line drug in myotonic syndromes , a group of muscle disorders characterized by membrane over - excitability . we previously showed that the -adrenoceptor modulators , clenbuterol and propranolol , block voltage - gated sodium channels in...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : majority of the cases of lymphangiomas are present at birth , 95% of the tumors arise before the age of 10 years ( watson and mccarthy ) . 88% of ...
### Summary: : the lymphangioma are benign hamartomatous tumors of lymphatic vessels that arises from the sequestration of lymphatic that fails to communicate with the lymphatic system . most common intra oral site being the anterior two - thirds of tongue , usually superficial in location and demonstrates a pebbly...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : diffuse dermal angiomatosis ( dda ) is a rare , acquired , reactive vascular proliferation , clinically characterized by livedoid erythematous viol...
### Summary: : abstractbackground : diffuse dermal angiomatosis ( dda ) is a rare , acquired , reactive vascular proliferation , clinically characterized by livedoid erythematous violaceous plaques , which frequently evolve to ulceration and necrosis . histopathologically , it is manifested by a diffuse proliferat...
<s> [INST] <<SYS>> You a helpful assistant capable of providing accurate and concise responses. You will assist me in generating Summary.<</SYS>> [/INST] <s> ### Text: : liver transplantation ( lt ) may result in significant blood loss and subsequent transfusion of red blood cells ( rbcs ) in most patients . althou...
### Summary: : background . significant amounts of red blood cells ( rbcs ) transfusions are associated with poor outcome after liver transplantation ( lt ) . we report our series of lt without perioperative rbc ( p - rbc ) transfusions to evaluate its influence on early and long - term outcomes following lt . ...