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results_new/confound_analysis.csv ADDED
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+ Analysis,rho,p
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+ Uncapped drift vs hosp,-0.3107142857142856,0.2596673973372179
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+ Capped (n=500) drift vs hosp,-0.3382352941176471,0.2000655587786896
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+ Partial Spearman (control n_seq),-0.13928571428571426,0.6205460876279014
results_new/drift_capped_h1n1.csv ADDED
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+ season,drift_raw,n_sequences,drift_norm
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+ 2025-26,2.7355633,357,0.3430778682231903
results_new/drift_capped_h3n2.csv ADDED
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+ season,drift_raw,n_sequences,drift_norm
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results_new/drift_capped_merged.csv ADDED
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results_new/drift_merged_tvae.csv CHANGED
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results_new/drift_merged_tvae_lag2.csv CHANGED
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results_new/drift_pca_h1n1.csv ADDED
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results_new/drift_pca_h3n2.csv ADDED
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results_new/drift_scores_tvae_h3n2_lag2.csv CHANGED
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1
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results_new/drift_scores_vae_h1n1.csv CHANGED
@@ -1,18 +1,18 @@
1
  season,drift_raw,n_sequences,drift_norm,subtype
2
- 2009-10,1.9473892,644,0.5,H1N1
3
- 2010-11,2.1451635,134,1.0,H1N1
4
  2011-12,3.6496725,42,1.0,H1N1
5
  2012-13,4.067254,34,1.0,H1N1
6
- 2013-14,3.87928,112,0.9113273024559021,H1N1
7
  2014-15,5.7052264,140,1.0,H1N1
8
- 2015-16,5.8229895,1524,1.0,H1N1
9
- 2016-17,1.5407356,548,0.0,H1N1
10
- 2017-18,2.7393959,1173,0.27991342544555664,H1N1
11
- 2018-19,1.4092766,2509,0.0,H1N1
12
- 2019-20,1.96578,2032,0.1260850876569748,H1N1
13
- 2020-21,2.792158,12,0.3133147358894348,H1N1
14
- 2021-22,2.9858384,105,0.35719627141952515,H1N1
15
- 2022-23,2.0820074,2170,0.1524183452129364,H1N1
16
  2023-24,1.1164455,6859,0.0,H1N1
17
- 2024-25,1.8971244,6310,0.16587093472480774,H1N1
18
- 2025-26,2.7379398,357,0.34451910853385925,H1N1
 
1
  season,drift_raw,n_sequences,drift_norm,subtype
2
+ 2009-10,1.9473889,644,0.5,H1N1
3
+ 2010-11,2.145164,134,1.0,H1N1
4
  2011-12,3.6496725,42,1.0,H1N1
5
  2012-13,4.067254,34,1.0,H1N1
6
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7
  2014-15,5.7052264,140,1.0,H1N1
8
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9
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10
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11
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12
+ 2019-20,1.9657799,2032,0.1260853260755539,H1N1
13
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14
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15
+ 2022-23,2.0820074,2170,0.1524185985326767,H1N1
16
  2023-24,1.1164455,6859,0.0,H1N1
17
+ 2024-25,1.8971254,6310,0.16587115824222565,H1N1
18
+ 2025-26,2.737941,357,0.34451940655708313,H1N1
results_new/drift_scores_vae_h1n1_lag2.csv CHANGED
@@ -1,17 +1,17 @@
1
  season,drift_raw,n_sequences,drift_norm
2
- 2010-11,3.0683653,134,0.5
3
  2011-12,4.466566,42,1.0
4
- 2012-13,3.3756998,34,0.21980707347393036
5
  2013-14,5.265854,112,1.0
6
  2014-15,6.6002417,140,1.0
7
- 2015-16,3.2982664,1524,0.06509318202733994
8
  2016-17,5.7733173,548,0.7658682465553284
9
- 2017-18,2.9352663,1173,0.0
10
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11
- 2019-20,2.5310476,2032,0.0
12
- 2020-21,3.5731637,12,0.2560989260673523
13
- 2021-22,2.7042725,105,0.0425698384642601
14
- 2022-23,3.9308312,2170,0.3439953029155731
15
  2023-24,2.2295303,6859,0.0
16
- 2024-25,2.0052493,6310,0.0
17
- 2025-26,3.342078,357,0.2909316420555115
 
1
  season,drift_raw,n_sequences,drift_norm
2
+ 2010-11,3.0683656,134,0.5
3
  2011-12,4.466566,42,1.0
4
+ 2012-13,3.375699,34,0.21980643272399902
5
  2013-14,5.265854,112,1.0
6
  2014-15,6.6002417,140,1.0
7
+ 2015-16,3.2982657,1524,0.06509292125701904
8
  2016-17,5.7733173,548,0.7658682465553284
9
+ 2017-18,2.9352658,1173,0.0
10
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11
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13
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14
+ 2022-23,3.9308307,2170,0.34399521350860596
15
  2023-24,2.2295303,6859,0.0
16
+ 2024-25,2.0052485,6310,0.0
17
+ 2025-26,3.342079,357,0.29093196988105774
results_new/drift_scores_vae_h3n2.csv CHANGED
@@ -1,18 +1,18 @@
1
  season,drift_raw,n_sequences,drift_norm,subtype
2
  2009-10,6.1183867,7,0.5,H3N2
3
- 2010-11,5.7967086,143,0.0,H3N2
4
- 2011-12,2.0311272,73,0.0,H3N2
5
- 2012-13,3.9450805,1091,0.4682730436325073,H3N2
6
- 2013-14,2.0806854,86,0.01212503481656313,H3N2
7
- 2014-15,1.7202483,1432,0.0,H3N2
8
- 2015-16,1.975741,1238,0.058091096580028534,H3N2
9
- 2016-17,2.12881,2591,0.09289420396089554,H3N2
10
- 2017-18,2.3091416,2572,0.13389603793621063,H3N2
11
- 2018-19,3.423726,3863,0.3873178958892822,H3N2
12
- 2019-20,3.6749094,929,0.4444291591644287,H3N2
13
- 2020-21,3.4970655,82,0.40399301052093506,H3N2
14
- 2021-22,0.98050576,5132,0.0,H3N2
15
- 2022-23,2.2399187,3829,0.24512304365634918,H3N2
16
- 2023-24,3.4316835,5106,0.4770795404911041,H3N2
17
- 2024-25,1.3332014,7078,0.0686461329460144,H3N2
18
- 2025-26,3.337307,2621,0.45871075987815857,H3N2
 
1
  season,drift_raw,n_sequences,drift_norm,subtype
2
  2009-10,6.1183867,7,0.5,H3N2
3
+ 2010-11,5.7967076,143,0.0,H3N2
4
+ 2011-12,2.031127,73,0.0,H3N2
5
+ 2012-13,3.9450798,1091,0.468272864818573,H3N2
6
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7
+ 2014-15,1.7202469,1432,0.0,H3N2
8
+ 2015-16,1.975742,1238,0.05809161812067032,H3N2
9
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10
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11
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12
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13
+ 2020-21,3.4970655,82,0.4039931893348694,H3N2
14
+ 2021-22,0.9805063,5132,0.0,H3N2
15
+ 2022-23,2.2399166,3829,0.2451225370168686,H3N2
16
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17
+ 2024-25,1.3332014,7078,0.06864603608846664,H3N2
18
+ 2025-26,3.3373048,2621,0.45871031284332275,H3N2
results_new/drift_scores_vae_h3n2_lag2.csv CHANGED
@@ -1,17 +1,17 @@
1
  season,drift_raw,n_sequences,drift_norm
2
  2010-11,3.8453658,143,0.5
3
- 2011-12,5.2308064,73,1.0
4
- 2012-13,4.1863084,1091,0.24608966708183289
5
- 2013-14,4.3651376,86,0.3751671612262726
6
- 2014-15,3.1048477,1432,0.0
7
- 2015-16,2.1606388,1238,0.0
8
- 2016-17,2.3748763,2591,0.0697803795337677
9
- 2017-18,2.9142287,2572,0.24545562267303467
10
- 2018-19,3.235539,3863,0.3501112461090088
11
- 2019-20,3.703335,929,0.5024794936180115
12
- 2020-21,4.142055,82,0.6453772187232971
13
- 2021-22,3.7562048,5132,0.5196999907493591
14
- 2022-23,2.3349288,3829,0.05676886811852455
15
- 2023-24,3.29202,5106,0.368507981300354
16
- 2024-25,3.4486716,7078,0.41953176259994507
17
- 2025-26,3.3143742,2621,0.375789076089859
 
1
  season,drift_raw,n_sequences,drift_norm
2
  2010-11,3.8453658,143,0.5
3
+ 2011-12,5.230807,73,1.0
4
+ 2012-13,4.1863074,1091,0.246088907122612
5
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6
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7
+ 2015-16,2.1606398,1238,0.0
8
+ 2016-17,2.3748758,2591,0.06977992504835129
9
+ 2017-18,2.9142292,2572,0.24545550346374512
10
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11
+ 2019-20,3.7033353,929,0.5024793148040771
12
+ 2020-21,4.1420565,82,0.6453774571418762
13
+ 2021-22,3.7562041,5132,0.5196995139122009
14
+ 2022-23,2.334928,3829,0.05676833540201187
15
+ 2023-24,3.2920172,5106,0.3685068190097809
16
+ 2024-25,3.4486709,7078,0.41953128576278687
17
+ 2025-26,3.314374,2621,0.37578874826431274
results_new/latent_diversity_tvae_h3n2.csv CHANGED
@@ -1,19 +1,19 @@
1
  season,latent_spread,latent_spread_std,latent_var_trace,n_sequences
2
- 2008-09,0.3514549,0.921172,0.976214968289716,236
3
- 2009-10,5.0459914,1.2687854,31.58382431818852,7
4
- 2010-11,3.7588248,1.789277,17.452317107739233,143
5
- 2011-12,5.1395073,1.2054205,28.25461974743554,73
6
- 2012-13,2.8362477,2.3693771,13.670779555635587,1091
7
- 2013-14,3.9855099,1.1299956,17.363077394110583,86
8
- 2014-15,4.058851,1.2284625,17.995957793368675,1432
9
- 2015-16,4.89944,1.1941148,25.450975881863467,1238
10
- 2016-17,4.604378,0.93995893,22.092346755584522,2591
11
- 2017-18,2.4751942,2.1737309,10.855912700633152,2572
12
- 2018-19,3.4912825,1.7975943,15.424391669523843,3863
13
- 2019-20,4.975693,1.2111263,26.25261122455143,929
14
- 2020-21,3.4024997,2.018207,15.843378189365517,82
15
- 2021-22,2.335761,1.903944,9.082552376398837,5132
16
- 2022-23,2.5314767,2.0475838,10.60374443876163,3829
17
- 2023-24,0.9588288,1.8945732,4.5096438741425455,5106
18
- 2024-25,2.4548104,2.8311925,14.043728122793624,7078
19
  2025-26,1.0069419,1.8738798,4.527084137220221,2621
 
1
  season,latent_spread,latent_spread_std,latent_var_trace,n_sequences
2
+ 2008-09,0.3514546,0.92117214,0.9762149682897161,236
3
+ 2009-10,5.0459924,1.2687854,31.58382431818852,7
4
+ 2010-11,3.7588248,1.7892768,17.45231710773923,143
5
+ 2011-12,5.1395073,1.2054204,28.25461974743554,73
6
+ 2012-13,2.8362472,2.3693776,13.670779555635583,1091
7
+ 2013-14,3.9855094,1.1299956,17.36307739411058,86
8
+ 2014-15,4.058851,1.2284625,17.995957793368678,1432
9
+ 2015-16,4.8994393,1.1941148,25.45097588186347,1238
10
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11
+ 2017-18,2.4751945,2.1737306,10.855912700633155,2572
12
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13
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14
+ 2020-21,3.4024997,2.018207,15.843378189365513,82
15
+ 2021-22,2.3357613,1.9039437,9.082552376398837,5132
16
+ 2022-23,2.5314765,2.0475843,10.60374443876163,3829
17
+ 2023-24,0.95882916,1.8945731,4.5096438741425455,5106
18
+ 2024-25,2.4548101,2.8311925,14.043728122793624,7078
19
  2025-26,1.0069419,1.8738798,4.527084137220221,2621
results_new/latent_diversity_vae_h3n2.csv CHANGED
@@ -1,19 +1,19 @@
1
  season,latent_spread,latent_spread_std,latent_var_trace,n_sequences
2
- 2008-09,3.313669,1.6013731,13.602436546379343,236
3
- 2009-10,9.784639,4.9600573,140.39821454604873,7
4
  2010-11,4.327881,3.2802498,29.69827083144147,143
5
  2011-12,5.98618,4.6923175,58.65569272259287,73
6
- 2012-13,3.8559673,1.3916547,16.820607908633896,1091
7
- 2013-14,3.8778977,1.1995859,16.670944256951593,86
8
- 2014-15,3.5541167,1.2522563,14.209813070619267,1432
9
- 2015-16,4.352375,0.8372987,19.660118630489066,1238
10
- 2016-17,4.1109977,1.09019,18.095800364470374,2591
11
- 2017-18,3.3771176,1.5626003,13.852027837700037,2572
12
- 2018-19,3.669112,1.2746193,15.09094246461552,3863
13
- 2019-20,4.588271,0.9704961,22.017796871390356,929
14
- 2020-21,2.9426322,1.6353238,11.473287626384167,82
15
- 2021-22,2.8177254,1.3714436,9.822348257539309,5132
16
- 2022-23,3.4422715,1.1090723,13.082690409720755,3829
17
- 2023-24,3.2002034,1.1856002,11.649229902045345,5106
18
- 2024-25,3.5912745,1.1871618,14.308626674583314,7078
19
- 2025-26,2.6462448,1.0272139,8.060856173055233,2621
 
1
  season,latent_spread,latent_spread_std,latent_var_trace,n_sequences
2
+ 2008-09,3.3136692,1.6013731,13.602436546379343,236
3
+ 2009-10,9.784638,4.960057,140.39821454604873,7
4
  2010-11,4.327881,3.2802498,29.69827083144147,143
5
  2011-12,5.98618,4.6923175,58.65569272259287,73
6
+ 2012-13,3.8559682,1.3916544,16.82060790863389,1091
7
+ 2013-14,3.877897,1.199586,16.670944256951593,86
8
+ 2014-15,3.5541167,1.2522563,14.209813072784906,1432
9
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10
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11
+ 2017-18,3.3771179,1.5626004,13.85202783619405,2572
12
+ 2018-19,3.6691117,1.2746196,15.09094246330621,3863
13
+ 2019-20,4.588271,0.9704963,22.017796870978476,929
14
+ 2020-21,2.9426324,1.6353238,11.473287626384169,82
15
+ 2021-22,2.8177254,1.3714434,9.822348258626306,5132
16
+ 2022-23,3.4422715,1.1090722,13.082690408797582,3829
17
+ 2023-24,3.2002034,1.1856,11.649229902205231,5106
18
+ 2024-25,3.5912743,1.187162,14.30862667396526,7078
19
+ 2025-26,2.6462448,1.027214,8.060856172930706,2621
results_new/metric_sensitivity.csv ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
1
+ Metric,Hamming rho (H3N2),Hamming rho (H1N1),SIRC RRMSE
2
+ Euclidean,0.5950924725000538,0.6170025601968426,5.83212788224093
3
+ Cosine,0.7705527272784202,0.6354756907416583,6.997946055044874
4
+ Wasserstein,0.5656445975722161,0.6194656442694847,5.66575180941653
results_new/power_analysis.csv ADDED
@@ -0,0 +1,6 @@
 
 
 
 
 
 
 
1
+ Effect size (rho),Power
2
+ 0.3,0.18854984672965175
3
+ 0.4,0.3115224846353255
4
+ 0.5,0.4772841587149417
5
+ 0.6,0.6704608842296238
6
+ 0.7,0.8518624581532503
results_new/representation_comparison.csv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ Method,Hamming rho (H3N2),Hamming rho (H1N1),SIRC RRMSE
2
+ PCA (64-dim),-0.2539879212526003,0.4310397127123651,1.1306851373801727
3
+ Conv1D VAE (64-dim),0.5950924725000538,0.6170025601968426,5.858599447568707
results_new/sirc_params_tvae.csv CHANGED
@@ -1,10 +1,10 @@
1
  ,0
2
- delta_min,0.0031697736121714115
3
- delta_max,0.04337846487760544
4
  S0_base,0.3173694610595703
5
  ihr,0.008885985240340233
6
  beta,0.3
7
  gamma,0.2
8
  sigma,0.008333333333333333
9
  mu,3.6529680365296805e-05
10
- calib_rrmse,8.669933319091797
 
1
  ,0
2
+ delta_min,0.003169772680848837
3
+ delta_max,0.04337845742702484
4
  S0_base,0.3173694610595703
5
  ihr,0.008885985240340233
6
  beta,0.3
7
  gamma,0.2
8
  sigma,0.008333333333333333
9
  mu,3.6529680365296805e-05
10
+ calib_rrmse,8.66993236541748
results_new/sirc_params_vae.csv CHANGED
@@ -1,5 +1,5 @@
1
  ,0
2
- delta_min,0.004339590668678284
3
  delta_max,0.02310071513056755
4
  S0_base,0.39473336935043335
5
  ihr,0.011631572619080544
@@ -7,4 +7,4 @@ beta,0.3
7
  gamma,0.2
8
  sigma,0.008333333333333333
9
  mu,3.6529680365296805e-05
10
- calib_rrmse,6.689363479614258
 
1
  ,0
2
+ delta_min,0.004339590203016996
3
  delta_max,0.02310071513056755
4
  S0_base,0.39473336935043335
5
  ihr,0.011631572619080544
 
7
  gamma,0.2
8
  sigma,0.008333333333333333
9
  mu,3.6529680365296805e-05
10
+ calib_rrmse,6.689363956451416
results_new/sirc_params_vae_lag2.csv CHANGED
@@ -1,8 +1,8 @@
1
  ,0
2
- delta_min,0.004489263519644737
3
  delta_max,0.021894609555602074
4
  S0_base,0.3526150584220886
5
- ihr,0.010617885738611221
6
  beta,0.3
7
  gamma,0.2
8
  sigma,0.008333333333333333
 
1
  ,0
2
+ delta_min,0.004489264916628599
3
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4
  S0_base,0.3526150584220886
5
+ ihr,0.010617884807288647
6
  beta,0.3
7
  gamma,0.2
8
  sigma,0.008333333333333333
results_new/sirc_simulation_tvae.csv CHANGED
@@ -1,22 +1,22 @@
1
  season,drift_blended,hosp_obs,hosp_sim
2
- 2010-11,0.0,21.5,0.092914656
3
- 2010-11,0.0,21.5,0.092914656
4
- 2011-12,0.25877763328998704,8.7,20.738436
5
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1
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results_new/sirc_simulation_vae.csv CHANGED
@@ -1,22 +1,22 @@
1
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2
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1
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2
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results_new/sirc_simulation_vae_lag2.csv CHANGED
@@ -1,22 +1,22 @@
1
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1
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