title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Escherichia coli mutants incapable of supporting replication of F-like plasmids at high temperature: isolation and characterization of mafA and mafB mutants. | Mutants of Escherichia coli K-12 defective in replication of F-like plasmids at a high temperature (42 degrees C) were found among threonine-independent (Thr+) revertants of a threonine-requiring F' stain after localized mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. Transduction experiments with phage P1 permi... | 391,803 | [
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AMP deaminase from baker's yeast. Kinetic and molecular properties. | The kinetic and molecular properties of AMP deaminase [AMP aminohydrolase, EC 3.5.4.6] purified from baker's yeast (saccharomyces cerevisiae) were investigated. The enzyme was activated by ATP and dATP, but inhibited by Pi and GTP in an allosteric manner. Alkali metal ions and alkaline earth metal ions activated the en... | 391,808 | [
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Observation of cultured embryonic epithelial cells in side view. | Epithelial cells from the early chick embryo were explanted and grown on a strip of coverglass which was positioned in a culture chamber in such a way that the cells could be filmed in side view. Ruffling of the cells at the leading edge of the sheet (marginal cells) appeared similar to the ruffles at the leading lamel... | 391,813 | [
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Ureolytic Escherichia coli of human origin: serological, epidemiological, and genetic analysis. | Forty-five strains of ureolytic Escherichia coli of human origin, isolated in the United States between 1956 and 1977, were characterized by geographical distribution, site of infection, serotype, resistance to antibiotics, and biochemical reactions. All strains were studied for the ability to generate clones of nonure... | 391,817 | [
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[Studies on the cutting ability of dental diamond points--the trial manufacture of the cutting test apparatus (author's transl)]. | Diamond points and tungstencarbite burs are used as the dental cutting tools for many appliance accordingly with the many purpose of used positions. Notwithstanding that the dental cutting tools have been usually applied for many purpose of dental treatment, the paper on these studies have scarcely been reported. In th... | 392,020 | [
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Relationships between Hand Test variables and mental retardation: a confirmation and extension. | Eighty-one mentally retarded individuals, including a range of deficiencies (severe, moderate, and mild), were given the Hand Test in order to investigate the relationship between IQ and personality. There were significant correlations between Hand Test personality variables and IQ and different subgroup configurations... | 392,070 | [
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On defining the thermal history of cells during the freezing of biological materials. | An explicit numerical finite difference scheme for defining the thermal history of a cell or group of cells contained within a biological sample of prescribed shape is described. Solutions are presented for three different cases of freezing of biological materials prior to microscopic examination. It is concluded that ... | 392,106 | [
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Renal transport of amino acids. | According to recent experimental data the renal transport of amino acids (AA) is characterized as follows. 1. Kinetics: Several reabsorption systems remove AA from the tubular fluid by active transport with Michaelis-Menten type kinetics. Passive diffusion does play only a relatively small role in reabsorption, but det... | 392,175 | [
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Systemic involvement in tuberculoid leprosy--pathogenesis of leprosy. | Occurrence of leprous pathology/bacilli in the internal organs in cases of polar tuberculoid leprosy, support the systemic nature and haematagenous transmission and spread of the disease process. Pathogenesis of leprosy has been postulated. | 392,191 | [
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The gene for ribosomal protein L25 (rplY) maps at 47.3 min near nalA in Escherichia coli K-12. | A temperature sensitive mutant, termed JE1306, derived from Escherichia coli strain PA3092 was found to have an alteration in the ribosomal protein L25. Crosses with various Hfr strains and transductions with P1 kc phage have revealed that the mutation maps at 47.3 min between nalA and fpk, in a region where no ribosom... | 392,236 | [
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Sporulation of mitochondrial respiratory deficient mit- mutants of Saccharomyces cerevisiae. | The role of mitochondrial protein synthesis, electron transport, and four specific mitochondrial gene products on sporulation were studied in respiratory deficient mit- mutants. These mutants were isolated in an op 1 strain and localized on the mitochondrial genome by petite deletion mapping. All 153 mutations studied ... | 392,241 | [
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Cloning of bacteriophage PM2 DNA in Escherichia coli K12. | DNA fragments of phage PM2 restricted with Hin dIII endonuclease was cloned in the vector pBR 322 in an Escherichia coli K12 host. The attempt to clone full length PM2 DNA restricted with PstI endonuclease has been unsuccesful. From six randomly chosen recombinant clones DNA was purified and analysed with EcoRI, PstI a... | 392,243 | [
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[Surgical procedure in exploratory incision of the mamma (author's transl)]. | A comparison was made between two groups, each consisting of 50 women who had undergone an exploratory incision of the mamma because of suspected cancer at least one year and not more than two years previously. The women in group A underwent an operation in clinic A in which a radial incision was performed in the skin ... | 392,287 | [
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The mutagenicity of natural products from marine algae. | 5 polyhalogenated hydrocarbon natural products isolated from the marine red alga Plocamium spp. were tested for mutagenicity in the Ames reversion assay. All 5 of the compounds induced revertants in Salmonella typhimurium strains TA100 and TA1535, indicating the mutational events involved base substitutions. One of the... | 392,317 | [
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T and B lymphocytes of the regional lymph nodes in patients with carcinoma of uterine cervix. | A comparative study of the peripheral blood and the regional lymph nodes lymphocyte subpopulations at 25 patients with carcinoma of uterine cervix was carried out by non-immune rosettes and immunofluorescence methods. The lymph nodes of ten women not affected with any disease, but operated on the occasion of the trauma... | 392,325 | [
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Myopathies. | This paper reviews the recent advances in our knowledge of muscle disease. The use of muscle biopsy for diagnosis is discussed. The etiology, pathogenesis, and treatment of polymyositis/dermatomyositis are considered. The author discusses the clinical patterns, inheritance, and pathogenesis of progressive muscular dyst... | 392,333 | [
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[Treatment procrastination time in breast cancer and personality structure]. | Sixty patients with mammary cancer were studied in order to determine whether a connection between the tendency to delay medical treatment and a neurotic personality structure exists. The results are based on different personality factors that were investigated by means of the 16-PF test by Cattell. It could be shown t... | 392,383 | [
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[Colorectal cancer]. | Incidence of colorectal cancer is increasing during the last years. 5% of the population get affected. From these a group of patients with a higher carcinoma risk must be separated: that with adenomas, familial polyposis and ulcerative colitis. Nourishment seems to be one of the main factors for the development of canc... | 392,384 | [
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A new pressure measuring system for cushins and beds--with a review of the literature. | An interface pressure measuring device for the assessment of subject-cushion interface pressures at ten points has been described. Preliminary trials using 12 healthy subjects on four cushions and three spinal injury patients on six cushings, has been carried out. It was also found that the water and foam cushion distr... | 392,412 | [
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[Plasma cell beta-glucuronidase and monoclonal gammapathies (author's transl)]. | beta-glucuronidase activity, estimated cytochemically, is, in more than half cases of myeloma, very increased or decreased, compared to that found in benign dysglobulinemias, where this activity is normal. A very high or very low score makes sure the diagnostic of myeloma. The relations between the beta-glucuronidase a... | 392,416 | [
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[Enzymatic induction during isoniazid therapy (author's transl)]. | Enzyme induction by isoniazid was studied by urinary D-glucaric acid estimation in slow and fast acetylators. Isoniazid administration increases significantively the D-glucaric acid elimination in the two classes of patients. In fast acetylators, the glucaricaciduria increases regularly up to 1.8 fold the physiological... | 392,418 | [
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Deficient alternative complement pathway activity in newborn sera. | Neonatal susceptibility to overwhelming bacterial infection is commonly attributed to a relative deficiency in serum opsonic activity. However, few studies have compared the functional capacity of the classical complement pathway with that of the alternative complement pathway in the neonate. The opsonic activity of ni... | 392,430 | [
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Modern aspects of testing azole antifungals. | Difficulties in the in vitro testing of azole antimycotics are described. The value of minimal inhibitory concentration results are discussed and contrasted to those obtained with polyene antimycotics. | 392,484 | [
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Analysis of HLA-D region-associated molecules with monoclonal antibody. | A group of monoclonal antibodies directed against nonpolymorphic HLA-D antigens (human Ia antigens) was produced by somatic cell hybridization. One of these antibodies was used to analyze the two-dimensional polyacrylamide gel electrophoretic pattern of the HLA-D alloantigens from different HLA-D homozygous B-cell line... | 392,522 | [
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Prospective study of different methods and routes of administration of prostaglandin E2 to improve the unripe cervix. | Methods of vaginal and extra-amniotic prostaglandin administration to achieve ripening of the cervix as a preliminary to induction of labour are described. Three groups of twenty patients with unfavourable induction features were studied, each receiving prostaglandin E2 the evening prior to planned induction. One group... | 392,620 | [
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Bismuth toxicity in man II. Review of bismuth blood and urine levels in patients after administration of therapeutic bismuth formulations in relation to the problem of bismuth toxicity in man. | A survey of the leterature on bismuth toxicity in man in relation to blood level data, has revealed the necessity of distinguishing between lipid soluble and water soluble organic complexes of bismuth on the one hand and the simple inorganic salts of bismuth on the other hand. A characteristic feature of the former, il... | 392,661 | [
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Effects of some naturally occurring prostaglandins of the D-, E-, and I-type and synthetic analogues on adenylate cyclase of human fat cell ghosts. | The effects of various prostaglandins originating from arachidonic acid (prostaglandin E2, D2, I2) as well as of methylated analogues of prostaglandin E2 (16,16-dimethyl prostaglandin E2 and 15-S-methyl prostaglandin E2) on the human fat cell adenylate cyclase were studied. In addition, the stable breakdown product of ... | 392,663 | [
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Hapten-antibody conjugates as probes of the lymphocyte surface. | Various forms and applications of the hapten-sandwich method for labeling cell surface antigens are reviewed. This is a two-layer antibody technique: the first antibody that binds antigen has been chemically modified so that a number of hapten groups are attached; the second antibody is directed against the hapten and ... | 392,715 | [
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Documentation of environmental particulate exposures in humans using SEM and EDXA. | There is increasing awareness of health hazards from environmental and occupational exposures to particulates. Scanning electron microscopy (SEM) and energy dispersive x-ray analysis (EDXA) can document these exposures by analysis of small portions of cells, tissues and environmental samples. Previous work is briefly r... | 392,730 | [
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0.0368496,
0.7621891,
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Some aspects of structural organization in the cochlea of the bat, Pteronotus parnellii. | The scanning electron microscope was used to study some specific features of the organ of Corti in the bat, Pteronotus parnellii parnellii. The region of the outer tunnel and the external sulcus were analyzed in detail. Good visualization of the geometric arrangement of the external sulcus cells and the deep channels f... | 392,735 | [
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0.3544318,
0.2493511,
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Recruiting collapsed lung through collateral channels with positive end-expiratory pressure. | We studied reinflation of collapsed parts in excised normal human lungs through both the ordinary bronchial route and through collateral channels. A model of atelectasis was made either by simple collapse or by applying a positive pressure to the pleura and a negative to the airway. Five different ventilatory patterns ... | 392,747 | [
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0.001610619,
0.1176111,
0.037331... |
[Classification of tubular testicular atrophies in the diagnosis of sterility. Significance of the so-called "bunte Atrophie"]. | In the course of testicular biopsies from 2317 patients in the years 1969--1978 at the Institute of Pathology of Zurich University, 1165 cases with tubular atrophy were retrospectively examined and classified on the basis of distribution of atrophy on the one hand and degree of atrophy (progressive depopulation) on the... | 392,748 | [
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0.1606641,
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[Dental reconstruction with non-precious metal screws and posts]. | A short review of the current methods for restoring destroyed dental crowns by mechanical retentive elements. The causes leading to failure in such restorations are mentioned in a short review of literature. Main causes are corrosive changes in posts and screws anchored in root canals. This is why a special chapter dea... | 392,757 | [
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0.1229095,
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0.2742845,
0.09171265,
... |
Immunologic aspects of breast feeding, antiinfectious activity of breast milk. | The most apparent immunologic role of the mammary gland is supply to antibodies to the neonate. In cattle the gland must be able to secrete large quantities of IgG antibodies over a short time period to supply the offspring with protection against systemic pathogens. This is accomplished by selective transfer of IgG fr... | 392,768 | [
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0.2118051,
-0.29360... |
The role of the dentist in the comprehensive management of hemophilia. | Routine dental procedures do not generally involve bleeding; consequently, there is no contraindication to routine dental treatment for hemophiliacs. Preventive dentistry is vital to the younger hemophiliac patient world-wide; older hemophiliacs may require extensive treatment to restore mouths that have been neglected... | 392,775 | [
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0.05851056,
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Lobectomy with sleeve resection of the bronchus for malignant disease of the lung and the influence of the suture material used for the bronchial repair. | A series of 100 consecutive cases of lobectomy combined with sleeve resection of the bronchus for malignant disease of the lung is presented. In 13 of these cases a sleeve resection of the appropriate pulmonary artery was also carried out. An operative mortality of 8% was encountered and a crude 5-year survival of 40% ... | 392,807 | [
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0.1485104,
0.5606453,
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0.0734581... |
Leucocyte migration inhibition test in cadaveric renal transplantation. | The leucocyte migration inhibition test has been studied in a series of 192 renal allograft recipients. Seventy-seven patients showed no evidence of inhibition in the early post-transplant course, but 31 of these demonstrated clinical evidence of rejection, a false-negative rate of 16%. The remaining 115 recipients all... | 392,833 | [
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0.2113636,
0.03488932,
... |
[Preparation of autodermal transplants for plastic surgery]. | The bacteriological examination of skin grafts prepared by V. N. Yanov's method, has confirmed a sufficient efficiency of such treatment of transplants for burried plasty. | 392,893 | [
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0.1342229,
0.4824604,
0.08804599,
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... |
[Kidney functional dynamics in eliminating vasorenal hypertension by a kidney autograft]. | In acute and chronic experiments on 45 dogs the authors obtained vasorenal hypertension, the elimination of which was fulfilled by means of autotransplantation of the kidney without transection of the ureter. The dynamical study of renal function was carried out through an analysis of arterial blood pressure, erythropo... | 392,899 | [
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0.09371938,
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[Systemic treatment of oral lichen planus with an aromatic retinoid (Ro 10-9359)]. | Experiences in the treatment of lichen planus mucosae (including the erosive type) are reported. Good therapeutical results could be obtained in all patients. Leukoplakic patches showed a partial involution and in some cases erosive alterations healed completely. After interruption of medication a relapse was observed ... | 392,969 | [
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0.125926,
0.327567,
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[Reactive changes in the hypothalamus after implantation of bipolar insulated electrodes and electrostimulation of the adenohypophyseotropic zone]. | Histological changes were studied in the hypothalamus of cats in a stereotaxic implantation into the middle zone of bipolar electrodes both by electrostimulation and without it. A wider zone of pathology is localized near the active surface of electrodes, around which a layer capsule is formed and which is surrounded e... | 393,014 | [
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0.1069911,
... |
Corneal transplantation and HLA histocompatibility. A preliminary communication. | A series of 222 cases of 7 mm penetrating corneal grafts were analysed with respect to the influence of HLA compatibility. The degree of compatibility was random as no matching was done (HLA types unknown at time of operation). Consequently, most of the cases showed 3 or 4 incompatibilities. The series was divided into... | 393,056 | [
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0.002721176,
0.01742329,
0... |
Effects of corneal preservation, donor age, cadaver time and postoperative period on the graft endothelium. A specular microscopic study. | The endothelia of 102 clear human corneal grafts in 95 patients were photographed in vivo with a specular microscope. The endothelial cell densities of the grafts were counted from a area of 0.01 mm2. The follow-up period averaged three years. The patients' ages ranged from 16 to 77 years and that of the donors from 8 ... | 393,058 | [
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0.3533528,
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Ketotic hypoglycemia of childhood--a clinical trial of several unifying etiological hypotheses. | We have studied 15 children referred to St. Göran's Children's Hospital because of suspected ketotic hypoglycemia. The patients were investigated according to a program designed to test several hypotheses--old and new--postulated to explain the etiology of ketotic hypoglycemia. We have used the classical ketogenic prov... | 393,061 | [
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0.3364861,
0.2295123,
0.1002228,
-0.02... |
Hepatic changes in late canine endotoxin shock. A light and electron microscopic investigation. | The patho-morphological lesions in the liver in late stages of canine endotoxin shock were studied by light and electron microscopy. Light microscopic lesions included sinusoidal dilatations, with accumulation of red cells and leucocytes, varying damage of the sinusoidal lining, microthrombi and widening of the space o... | 393,072 | [
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0... |
Penicillamine in rheumatoid arthritis. | Perhaps the most important conclusion is that much remains to be learnt about how to use penicillamine in clinical practice. The results described have been obtained by observing groups of patients on various fixed schedules of dosage. There may be a case for using a more flexible system but this makes comparisons diff... | 393,102 | [
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0.1136401,
0.1652186,
0.095... |
[Perfluorochemical-emulsion (fluorocarbon-43) as blood gas carrier--fate of the substance after intravenous injection in rat (author's transl)]. | The present paper concerns light and electron microscopic studies on cellular uptake and deposition of the oxygen and carbondioxide carrying substance "Fluorocarbon-43" after intravenous injection in rats. Phagocytosis of "Fluorocarbon-43" by blood monocytes, histiocytes, endothelial macrophages (i.e.v. Kupffersche cel... | 393,124 | [
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0.6636271,
-0.0876522... |
Role of macrophage activation in allograft immunity: in vivo studies. | Macrophage-rich adherent peritoneal cells from mice sensitized by two i.p. injections of allogeneic cells at days -- 12 and --2, were found non-specifically cytotoxic against (a) tumoral target cells, as evaluated by the chromium release test, and (b) normal target cells, as evaluated by a functional test based on the ... | 393,160 | [
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0.3376655,
0.02708682,
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Separation of botulinum-positive and -negative fish samples by means of a pattern recognition method applied to headspace gas chromatograms. | A gas chromatographic headspace technique was used to analyze the gas produced during putrefaction of pond-raised, degutted trout, incubated in evacuated plastic pouches. The following samples were analyzed; 10 samples which, due to natural contamination with Clostridium botulinum, were toxic when injected into mice, 1... | 393,168 | [
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0.3134781,
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The concentration of chloroquine in serum during short and long term malaria prophylaxis with standard and 'double' dosage in non-immunes: clinical implications. | The concentration of chloroquine in serum was analysed after one week, six weeks and one year on standard dose prophylaxis (300 mg chloroquine base once a week) and after six months on the double dose. After six weeks, the standard dose gave adequate protection against malaria. During the first weeks of prophylaxis ins... | 393,188 | [
-0.1905153,
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0.2153326,
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... |
Mass lesion of the breast after augmentation mammoplasty. | Examination of the breast after augmentation mammoplasty may be relatively easy, but the evaluation of a mass lesion presents particular possibilities and problems. Closed compression capsulotomy occasionally results in rupture of the gel prosthesis, and when silicone contacts the surrounding breast tissue, a firm gran... | 393,205 | [
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0.02676324,
0.01939286,
... |
Living related renal transplantation: experience in 22 cases. | Twenty-two living related renal transplant operations have been performed at Prince Henry's Hospital over the last seven years. Donors have been accepted for nephrectomy only after exhaustive examination of their health and serach for renal disease. The one and three year graft survival rates have been 85% and 64% resp... | 393,227 | [
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0.4766678,
-0.1390513... |
Candidiasis in cockatiel nestlings and mucormycosis in a pigeon. | Deaths of cockatiel nestlings caused by Candida albicans, and of a pigeon caused by air-sac infection with Absidia corymbifera, are described. Lesions in the cockatiels were pseudomembranes and ulcers in the mouth, esophagus, and crop. In the pigeon the air sacs were thickened and contained a grayish gelatinous exudate... | 393,241 | [
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0.5129055,
0.1605322,
0.04336591,
0.... |
A comparative study of methyldopa and labetalol in the treatment of hypertension. | 1 Twenty patients with essential hypertension completed a double-blind, dose-tritrated, cross-over comparison of methyldopa and labetalol. 2 Average lying BPs (systolic/diastolic) were reduced by 28/15 mmHg with methyldopa and by 23/15 mmHg with labetalol. 3 Average standing BPs (systolic/diastolic) were reduced by 29/... | 393,286 | [
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0.1624392,
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0.2769082,
-0.06077175,
... |
Effect of luteinizing hormone-releasing hormone on plasma testosterone in immature and adult male rabbits. | 1 microgram/100 g body weight of synthetic luteinizing hormone-releasing hormone (LHRH) was administered to immature (25, 35 and 55 days of age) and adult (180 days) male rabbits. Testosterone was measured by radioimmunoassay in plasma samples taken just before and 30 min after LHRH injection. At all stages studied, LH... | 393,307 | [
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0.2263097,
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0.1256617,
0.1261997,
0.03222709,
0.5547702,
0.4505967,
0.02372499,
-... |
Prolongation of murine skin allografts across a major histocompatibility locus using supernatants from con-A activated spleen cells. | Supernatants from Concanavalin A-activated mouse spleen cell cultures have been found to prolong skin graft survival across the H-2 locus in the mouse. There exist in these supernatants non-specific factors synthesized by suppressor T cells which have been activated by sub-optimal concentrations of Concanavalin A in vi... | 393,314 | [
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0.2585799,
0.2956757,
0.1467172,
0.1988997,
-0.168458,
... |
Chemoimmunotherapy (DTIC and Corynebacterium parvum) as adjuvant treatment in malignant melanoma. | Sixty-one patients with stage I or II (lymph node involvement) malignant melanoma were prospectively randomized into a control group receiving surgical treatment only (consisting of wide excision of primary and regional node dissection) and a group receiving the same surgical treatment plus adjuvant therapy with DTIC a... | 393,377 | [
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In vitro response of chloroquine-resistant Plasmodium falciparum to mefloquine. | The present study was conducted to evaluate the application of the in vitro microtechnique system in determining the response of chloroquine-resistant Plasmodium falciparum to mefloquine.Using isolates of P. falciparum from Boa Vista, Brazil, and Villavicencio, Colombia, mefloquine was more than 7.7, 7.1, 7.1, and 6.4 ... | 393,426 | [
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A rapid and simple sandwich-method used for chromosome analysis from small fetal and adult biopsy specimens. | A new Sandwich-Method is described which uses aborted material and yields a high frequency of metaphases. Chromosome studies may be performed after 7--8 days without subculturing. It is possible to freeze the original tissue for later cell culture. | 393,436 | [
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Antibodies directed against renal collecting ducts in sera of human renal allograft recipients. | Anatibodies directed against the plasma membrane of renal collecting ducts were found in the sera of two out of 101 renal allograft recipients. The sera also reacted with the epithelium of the renal pelvis, the ureter, the ductus deferens, the skin, the oesophagus, the trachea and the bile ducts of random individuals, ... | 393,442 | [
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Physiological characteristic and energy balance of Klebsiella aerogenes in a multistage tower fermentor. | Biomass growth, consumption of carbon and energy source, specific rates of formation of metabolic byproducts, biomass yield referred to the C-source and to oxygen, respiration rate and the value of RQ were studied in Klebsiella aerogenes CCM 2318 (on a synthetic glucose medium) at different specific growth rates. Maint... | 393,594 | [
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Skin-window study on the migration of leukocytes of newborns and infants. | Migration of leukocytes of newborns and of infants up to the age of 6 months was studied using the in vivo skin-window technique according to Rebuck. Using the non-specific stimulation (abrasion of the skin only) a slight age-dependent physiological increase of migration of cells was observed within the observation per... | 393,596 | [
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Endocrine pancreatic cells of postnatal "diabetes" (db) mice in cell culture. | Ultrastructural characteristics as well as secretory and biosynthetic behavior of monolayer pancreatic cell cultures established from 4-day-old C57BL/KsJ misty diabetic (m db/m db) mice have been studied in comparison to normal littermate controls. Hypersecretion of glucagon by alpha-cells from BL/Ks misty diabetic mic... | 393,618 | [
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Malignant behaviour of three adenovirus-2-transformed brain cell lines and their methyl cellulose-selected sub-clones. | Three adenovirus-2-transformed rat embryo brain cell lines and their methylcellulose-selected sub-clones were examined for fibronectin expression, anchorage-independent growth, saturation density, T antigen expression and morphology. Tumorigenicity studies were carried out on newborn and ATS immunosuppressed syngeneic ... | 393,638 | [
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Characterization of methanol extraction residue (MER) from Bacillus Calmette-Guérin (BCG). | Analysis of methanol extraction residue (MER) from Bacillus Calmette-Guerin (BCG) was carried out to determine some specific chemical compositional characteristics. Samples of MER were found to contain approximately 40% protein and/or peptide, 3% soluble lipids, 17% bound lipids, 8% elemental nitrogen, and less than 2%... | 393,679 | [
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Free amino acids in blood of ruminants--physiological and nutritional regulation. | Tissue free amino acid pools account for only a small fraction of the total amino acid content in the body. Blood of plasma free amino acid pools represent only a very small proportion of tissue free amino pools. Plasma free amino acid profiles have been used as a tool to study nutritional and metabolic aspects of prot... | 393,693 | [
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Immunoreactive alpha and beta subunits of follicle stimulating and luteinizing hormones in peripheral blood throughout the menstrual cycle and following stimulation with synthetic gonadotropin releasing hormone (GnRH). | The concentration of immunoreactive alpha and beta subunits of human LH (hLH) and human FSH (hFSH) were measured in unfractionated serum throughout normal menstrual cycles, and when GnRH was administered at about midcycle. The RIA subunit systems employed were sufficiently sensitive and specific to measure basal levels... | 393,752 | [
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Interrelation of DNA replication, specific growth rate and growth temperature in the sensitivity of Escherichia coli to cold shock. | Escherichia coli W3110 was grown in a chemostat under conditions of carbon limitation at various temperatures and specific growth rates (mu). Exponential survivor-time curves following cold osmotic shock were biphasic. These could be described by the sum of two exponential functions representing the survival of sensiti... | 393,799 | [
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[Methods available for measuring temperature (author's transl)]. | Numerous techniques are in use in medicine for temperature determination either from thermal conduction phenomena, or from hot body radiations. These are essentially thermometry, radiometry and thermography. During attempts to treat cancer by hyperthermia, temperature knowledge, at the level of the target volume and th... | 393,820 | [
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Growth and survival studies of psychrophilic and mesophilic yeasts. | The effect of temperature on the growth of members of five genera of yeasts was studied in one glucose-containing and two glucose-free media. The maximum growth rate was seen in the glucose-containing medium, and the minimum growth was in either of the two glucose-free media depending upon the organism. Data obtained b... | 393,960 | [
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Fatty acid alpha-hydroxylation and its relation to myelination. | alpha-Hydroxylation is an enzymatic reaction by which long-chain fatty acids are converted to their alpha-hydroxy derivatives. This reaction, in animals, can be detected only in developing brain and is the rate-determining step in the synthesis of hydroxycerebroside, which is an indispensable and abundant myelin lipid.... | 393,993 | [
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Cytochemical and biochemical identification of lysosomes in Cryptococcus neoformans. | Normaski optics, fluorescence and electron microscopy were employed to demonstrate the occurrence of lysosomes in capsulated, enztmatically decapsulated, and dewalled cells of a human isolate of Cryptococcus neoformans. Fluorescent studies, using acridine orange as a lysosomal indicator, revealed the presence of variou... | 394,002 | [
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Quantitative analysis of dendritic branching. I. Simple formulae for the quantitative analysis of dendritic branching. | Dendritic branching of neurons may be quantitatively studied using applications of graph theory. Dendritic ramifications may be considered as 'forests' of planted, stemmed, binary 'trees' with simple mathematical properties. Two fundamental numbers, that of dendritic tips and that of dendritic stems, usually suffice to... | 394,030 | [
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Dislocation of Binkhorst four-loop lens implant. | A consecutive series of 1,093 Binkhorst four-loop lens implantations was used to examine the problem of dislocation of implants used in intracapsular cataract extractions; emphasis of the study was on the need for suture fixation. Transiridectomy suture fixation was used in 497 procedures, no suture was used in 403 pro... | 394,063 | [
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-0.121... |
[Utilization of the Kato-Katz-method (thick-smear technique) the diagnosis of Isospora (author's transl)]. | Performing 10475 stool examination using the KATO-KATZ, HOFFMAN-PONS-JANER and direct examination (after agitation) methods, the author showed the best results with KATO-KATZ method for the diagnosis of Isospora hominis and Isospora belli. Among the 10475 stools examined 392 (3.74%) were positive for I. hominis and 55 ... | 394,228 | [
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Diclofenac (Voltarol) in rheumatoid arthritis: a report of a double-blind trial. | A double-blind trial compared diclofenac with placebo in 44 outpatients. On from each group dropped out with dyspepsia, and one (placebo group) with ineffective treatment. Twenty completers received diclofenac. Dosage was one tablet (25 mg diclofenac) three times daily during the first week. In the second (final) week,... | 394,280 | [
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[Studies concerning dysenteric infections in a closed children's community before and after antidysenteric vaccination. I. Epidemiological considerations on acute intestinal infections]. | In the closed children's community studied between 1 Jan. 1976 and 13 June 1977, a high proportion (54%) of the total number of acute intestinal infections was of dysenteric etiology, i.e. 46,9% in the 0--1 year age-group and 21,1% in the 1--3 years age-group, the dominant Shigella subtype being represented by Shigella... | 394,271 | [
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0... |
[Evaluation of the safety and effectiveness of WHR-1142A in the treatment of non-specific acute diarrhea]. | A randomized double-blind placebo controlled trial of the safety and efficacy of lidamidine hydrochloride (WHR-1142A) in thirty patients with acute nonspecific diarrhea was conducted. During their 29-hour hospital treatment period, the average number of bowel movements for each ten patient treatment group was: placebo,... | 394,268 | [
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0.1813055,
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0.2672935,
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[Treatment of Binder's maxillonasal dysostosis (author's transl)]. | The treatment of Binder's maxillonasal dysostosis raises many problems and difficulties of both orthodontic and surgical natures. Orthodontic therapy should be conducted as early as possible and include, principally, an advancement of the maxilla by heavy extra-oral postero-anterior traction on an orthodontic mask. If ... | 394,294 | [
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The release of enterokinase following secretin and cholecystokinin-pancreozymin in man. | The release of enterokinase into human duodenal fluid was studied after intravenous injections of secretin and cholecystokinin-pancreozymin (CCK-PZ). In five control subjects there was a significant release of the enzyme after stimulation with either hormone. A similar release of enterokinase was observed after hormona... | 394,301 | [
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A simple laboratory method for the diagnosis of V. cholerae. | In many developing countries where cholera occurs, bacteriological facilities at the local level are lacking and either cholera may be unreported or other diarrhoeal diseases may be mistakenly reported as cholera. A simple and practical method, suitable for use in small hospitals and health centres and by field teams o... | 394,411 | [
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Antisporozoite antibodies in mice immunized with irradiation-attenuated Plasmodium berghei sporozoites. | Sera from NMRI/NIH mice were tested for the presence of IgM and IgG anti-sporozoite antibodies using the indirect fluorescent antibody test (IFAT). Both IgM and IgG antibody titres were related to the number of immunizations with irradition-attenuated Plasmodium berghei sporozoites, and protection from challenge with s... | 394,412 | [
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The ultrastructural characterization of the tegument of Clonorchis sinensis (Cobbold, 1875) cercaria. | The tegumental ultrastructure of the cercaria of the liver fluke, Clonorchis sinensis (Cobbold, 1875), was studied by scanning and transmission electron microscopy. The body surface is almost encircled by many rows of regularly arranged spines. The tegumental syncytium of the body contains many rod-shaped dense granule... | 394,497 | [
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... |
Vaccination against virus diseases. | One of the most important and most lasting benefits of medicine to human health and health expenditure is the controlled immunological interruption of the vicious cycle of infectious disease such as smallpox, poliomyelitis, yellow fever, measles. Smallpox, with globally more than 2.5 million cases ten years ago, is gon... | 394,510 | [
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[Physiologic views of A. N. Radishchev]. | The analysis of A. N. Radischev's treatise "On man, his mortality and immortality" reveals a number of ideas which show that the author had a materialist approach to the problems, which in modern terms are the problems of the higher nervous activity. A great Russian materialist thinker, he naturally had a considerable ... | 394,505 | [
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[Immunology of pregnancy -- more recent aspects of immunological mother-child relations (author's transl)]. | An account is given of some topical aspects relating to immunology of pregnancy, with reference being made to more recent literature. Included are hypothetical considerations on undisturbed embryonic development, the barrier function of the placenta, the ontogenesis of the immune system, immunosuppressive factors of pr... | 394,535 | [
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Insulinogenic indexes in psoriasis. | We have earlier demonstrated that in psoriasis there exists a reduced tolerance to carbohydrates in association with hyperinsulinism. To pursue this problem further, we felt it worthwhile to deal with the results of the oral glucose tolerance test performed on 78 subjects (divided into homogenous groups of normal, obes... | 394,548 | [
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Cellular and humoral immunity in psoriatic patients. | The degree of cellular immunity was found to be reduced in about 23% of 56 psoriatics, especially so in those with flexural and arthropathic lesions. Humoral immunity was only slightly reduced. Lysozyme activity levels in serum were normal, while those of healthy skin were depressed in 6 patients. | 394,549 | [
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The assessment and meaning of intraobserver error in population studies based on discontinuous cranial traits. | Intraobserver scoring precision of 50 discontinuous (discrete) cranial traits was assessed on a sample of 125 intact Iroquois crania using the square of the phi coefficient. Scoring consistency was high for most traits although several were subject to low precision (phi 2 less than 0.7). Most errors were random rather ... | 394,603 | [
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Sedation for outpatient conservative dentistry. A trial of pentazocine supplementation to diazepam and local analgesia techniques. | Pentazocine 30 mg. or 15 mg or a placebo, was administered randomly to forty-nine patients undergoing conservative dental treatment in combination with a local analgesic block and intravenous diazepam. Simple cardiorespiratory measurements were made throughout the treatment period. Patients in the 30 mg pentazocine gro... | 394,624 | [
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Alzheimer neurofibrillary tangles: antiserum and immunohistological staining. | A 50,000-dalton polypeptide has been purified from fractions enriched with neurofibrillary tangles of paired helical filaments from human autopsy specimens of Alzheimer disease and senile dementia of the Alzheimer type. An antiserum to this polypeptide was raised in a rabbit. This antiserum formed an immunoprecipitatio... | 394,670 | [
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Comparison of m-Endo LES, MacConkey, and Teepol media for membrane filtration counting of total coliform bacteria in water. | Total coliform counts obtained by means of standard membrane filtration techniques, using MacConkey agar, m-Endo LES agar, Teepol agar, and pads saturated with Teepol broth as growth media, were compared. Various combinations of these media were used in tests on 490 samples of river water and city wastewater after diff... | 394,678 | [
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0.064... |
Prediction of solute transport during peritoneal dialysis. | Solute transport, predominantly diffusion, across the peritoneum correlates inversely with molecular weight. Provided that the solute is water soluble, not protein bound, not of unusual density, not ionized, does not have a large hydration shell, and is transported from plasma to dialysate, the peritoneal clearance is ... | 394,724 | [
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Counterregulatory system in an artificial endocrine pancreas. Glucose infusion algorithm. | An artificial endocrine pancreas has been developed by adding a glucose infusion system to the artificial beta cell system. In this computer algorithm, glucose is infused on the basis of proportional and derivative actions to blood glucose concentration with the time delay constant between blood withdrawal and initiati... | 394,725 | [
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0.03266316,
0.038936... |
A protease-antiprotease system in antrochoanal polyp. I. Evidence for the existence of proactivator. | Tissue extract of antrochoanal polyps showed a faint lysis area on standard fibrin plates, but streptokinase (SK)-added tissue extract showed a large lysis area. No fibrinolytic activity was observed on plasminogen-free fibrin plates. It is concluded, therefore, that the fibrinolytic activity observed after SK addition... | 394,730 | [
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A comparison of oral choline theophyllinate and beclomethasone in severe perennial asthma in children. | Fourteen children with perennial asthma previously treated with beclomethasone dipropionate were studied for four months in a crossover trial to compare the efficacy of choline theophyllinate and beclomethasone dipropionate aerosol in the control of their symptoms. Assessments were made using twice daily peak flow meas... | 394,754 | [
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... |
[Generalized periarthritis calcarea (generalized hydroxyapatite disease)]. | The condition of generalized periarthritis calcarea (hydroxyapatite deposition disease) is characterised by multiple periarticular calcification which can be localised around practically any joint and also in proximity to the spine. This calcification consists of hydroxyapatite crystals which are responsible for the ep... | 394,790 | [
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... |
Endourethral urethroplasty. | Following internal urethrotomy for treatment of strictures of the bulbous urethra, 11 patients had primary split skin grafts inlaid over the urethrotomy site. There were no operative complications and the results in 5 patients with a 9-month follow-up are good. | 394,797 | [
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Preliminary 3-year results of 12 versus 6 cycles of surgical adjuvant CMF in premenopausal breast cancer. | In hope of reducing the duration of adjuvant treatment in premenopausal patients with operable breast cancer and histologically positive axillary lymph nodes, a prospective controlled study was started in September 1975. A total of 160 patients were randomized to receive 12 cycles of adjuvant CMF, while 165 were alloca... | 394,864 | [
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0.3072768,
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... |
Paradoxes of psychotherapy. In honor and memory of Ludwig Binswanger. | Existential analysis has made us face the paradoxes, if not antinomies, in psychotherapy that we did not seem to be aware of. Existential philosophy is a highly elaborate, technical and linguisticly difficult field. In psychiatry, existential analysis of turned out to be just a set of hallowed commonplaces. As philosop... | 394,913 | [
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0.03557603,
0.1296303,
-0.03584529,
-0.202642... |
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