title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Platelet membrane glycoproteins in thrombasthenia, Bernard-Soulier syndrome, and storage pool disease. | Quantitative polyacrylamide gel electrophoresis has been carried out on patients with Bernard-Soulier syndrome, Glanzmann's thrombasthenia, and storage pool defect in order to clarify the abnormalities in their platelet membrane glycoproteins. Normal individuals had values (expressed as PAS staining units/mg of membran... | 429,863 | [
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Carbamazepine in the treatment of objective myoclonus tinnitus. | Three patients have had objective clicking tinnitus which was demonstrated by using impedance audiometry. Additionally EMG studies to localize the contracting muscle were performed, and EEG recordings to find the possible focal cortical activity. One patient had central nervous degenerative lesions. Carbamazepine was g... | 429,895 | [
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Giant aneurysm of the internal carotid artery in the carotid canal. | A case of giant aneurysm of the intrapetrous portion of the internal carotid artery, with intracranial and extra-cranial extension in an eight-year-old girl, is reported. Intracranial extension was demonstrated by the presence of a large sac projecting above the petrous shadow in a frontal carotid angiogram, and upward... | 429,908 | [
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Reinforcement contingencies as discriminative stimuli: II. Effects of changes in stimulus probability. | Three pigeons were trained on a matching procedure involving a sample component and a choice component. Responding in the sample component, according to either a differential-reinforcement-of-low-rate schedule on some trials or a differential-reinforcement-of-other-behavior schedule on other trials, produced access to ... | 429,958 | [
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Structural studies on the murine Ia alloantigens. V. Evidence that the structural gene for the I-E/C beta polypeptide is encoded within the I-A subregion. | The E/C alpha- and beta-subunits of intra-I-region recombinants were analyzed for primary structural variation by comparative tryptic peptide mapping. The E/C alpha-polypeptides from B10.A, B10.A (3R) and B10.A (5R) showed complete coincident elution of peptides; the E/C beta-chains from B10.A and 3R (or 5R) were appro... | 429,967 | [
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Teaching interpersonal skills in family practice: results of a national survey. | The increasing recognition of the importance of a well-developed set of interpersonal skills to the competent family physician has resulted in a rapid growth in the formal teaching of interpersonal skills within family practice residencies. Of the 168 programs responding to a national survey of family practice residenc... | 429,975 | [
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Effects of leukocyte and fibroblast interferon on events in the fibroblast cell cycle. | Serum-depleted human foetal skin fibroblasts were stimulated by addition of 10% foetal calf serum to proliferate synchronously for at least one cell cycle. This proliferation was suppressed by leukocyte or fibroblast interferon (IF), which prolonged the G1 phase and diminished the rate of DNA synthesis during the S pha... | 430,031 | [
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Multi-infarct dementia. | Fifty-two patients presenting with dementia were divided into a group in whom clinical features suggested an ischaemic basis (multi-infarct dementia) and a group in whom a primary degenerative process seemed more likely. Focal EEG changes and angiographic evidence of ischeamic areas and atheromatous disease of intracra... | 430,104 | [
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Response to sudden torques about ankle in man: myotatic reflex. | 1. Sudden dorsiflexions and plantarflexions of the foot were imposed on normal human subjects under various states of voluntary activity. 2. Under conditions of constant muscle contraction, the myotatic reflex in soleus and lateral gastrocnemius muscles is linearly and highly correlated with the rate of muscle stretch.... | 430,116 | [
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Alteration of posttraumatic ischemia in experimental spinal cord trauma by a central nervous system depressant. | Blood flow after severe experimental injury to the thoracic spinal cord was studied in cats, using a modification of the hydrogen clearance technique. Gamma hydroxybutyrate, a central nervous system depressant, was shown to markedly alter the ischemic response to injury if given during the early posttraumatic period. O... | 430,133 | [
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Computer-assisted static/dynamic renal imaging: a screening test for renovascular hypertension? | Computer-assisted static/dynamic renal imaging with [197Hg] chlormerodrin and [99mTc]pertechnetate was evaluated prospectively as a screening test for renovascular hypertension. Results are reported for 51 patients: 33 with benign essential hypertension and 18 with renovascular hypertension, and for 21 normal controls.... | 430,172 | [
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Imaging the adrenal medulla with an I-131-labeled antiadrenergic agent. | Tissue distributions of four antiadrenergic agents labeled with iodine-125 have been determined in dogs. [125I] ortho-iodobenzldimethyl-2-hydroxyethyl ammonium and [125I] ortho-iodobenzyldimethylethyl ammonium show highly selective uptake in the adrenal medulla. Studies of molecular structure-distribution indicate that... | 430,189 | [
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Interaction of zinc and essential fatty acids in the rat. | Three experiments were performed to investigate the possibility of a physiological relationship between zinc and essential fatty acids (EFA). Male weanling rats were fed diets low in zinc, EFA or both and their growth rates, dermal scores and tissue fatty acid profiles determined. In experiment 1, a basal soybean prote... | 430,250 | [
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Pyridoxine requirements of channel catfish. | In 20 and 12 week feeding trials, channel catfish fingerlings were fed purified diets containing five levels (0, 5, 10, 20, and 30 mg/kg) and six levels (0, 1, 2, 5, 10, and 20 mg/kg) of supplemental pyridoxine hydrochloride. Fish fed unsupplemented diets (pyridoxine content of 1.2 mg/kg) were characterized by anoxeria... | 430,257 | [
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Increase in metabolic rate of the alligator fed proteins or amino acids. | Energy required for protein digestion, amino acid absorption and transport, and for protein synthesis in the alligator was estimated by determining oxygen consumption following feeding of single amino acids, various amino acid mixtures, fish, casein, gelatin, zein, and a gelatin hydrolysate. Results suggested a low ene... | 430,258 | [
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Outcome of early experience studies as affected by between-litter variance. | Studies of early experiences in animals in which the mother or the entire litter is manipulated often involve significant levels of between-litter variance. Such variance, if not accounted for either by analysis which considers litter as an independent source of variance, or by use of mean litter scores, may contribute... | 430,265 | [
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Mechanism for fatty liver induction in rats fed arginine deficient diets. | Arginine deficiency is known to lead to marked alterations in pyrimidine biosynthesis and the excessive loss of urinary orotic acid. Orotic acid feeding is known to lead to hepatic steatosis. These studies show that arginine deficiency also results in a marked increase in liver lipids in the rat. The majority of the in... | 430,266 | [
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SC 25152: a potent mineralocorticoid antagonist with decreased antiandrogenic activity relative to spironolactone. | The widely used mineralocorticoid antagonist spironolactone has antiandrogenic activity that may contribute to its side effects of decreased libido, impotence and gynecomastia. We have therefore sought a less antiandrogenic analog of spironolactone that may exhibit reduced endocrine side effects. The analog SC 25152 wa... | 430,374 | [
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Motor unit organization of human medial gastrocnemius. | 1. The properties of fifty-seven motor units in human medial gastrocnemius have been studied using controlled intramuscular microstimulation, glycogen depletion and muscle biopsy. 2. Motor units could be divided into three classes on the basis of their mechanical properties. Type S units were slow, small and fatigue re... | 430,414 | [
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Differential alteration by hypercapnia and hypoxia of the apneustic respiratory pattern in decerebrate cats. | 1. A combination of bilateral lesions within the nucleus parabrachialis medialis complex (n.p.b.m.) and bilateral vagotomy typically resulted in an apneustic respiratory pattern in decerebrate and paralysed cats. Integrated efferent phrenic nerve activity was recorded as an index of the respiratory rhythm.2. Changes in... | 430,430 | [
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Relationship between attitudes toward feminism and levels of dogmatism, achievement, and anxiety. | More than 1,500 American women from a wide range of age, socioeconomic, and educational backgrounds were administered measures of dogmatism, anxiety, achievement, and feminism. One hundred nine Ss who scored above the 75 percentile on the Attitudes Toward Women Scale (high supporters of the feminist movement) were matc... | 430,450 | [
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[Thoracic and retroperitoneal cystic lymphangiomyomatosis. Value of lymphography]. | Standard radiological examinations in a woman of 40 years of age with a pneumothorax and chylothorax revealed the presence of a posterior mediastinal mass compressing the oesophagus, and an interstitial syndrome. Retroperitoneal and mediastinal cystic lymphangiomas were found on lymphography. These findings are in acco... | 430,456 | [
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Structure-activity relationships of dimeric Catharanthus alkaloids. 2. Experimental antitumor activities of N-substituted deacetylvinblastine amide (vindesine) sulfates. | While structure-activity relationships for vinblastine (VLB), vincristine, deacetyl-VLB, and deacetyl-VLB amide (vindesine, VDS) in several tumor and leukemia models have been reported previously, the present study explores these relationships for a series of N-substituted vindesine analogues. These compounds were prep... | 430,477 | [
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Use of nitrogen-specific detector for GLC determination of plasma bucainide. | A sensitive and specific GLC determination of plasma bucainide was developed using a nitrogen-specific detector. The method permits the determination of bucainide as low as 5.0 ng/ml of plasma and provides sufficient sensitivity and reproducibility for clinical use. | 430,491 | [
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Enthalpy of bile salt-lecithin mixed micelle formation. | The enthalpies for the dissolution of lecithin by sodium salts of cholic, deoxycholic, and chenodeoxycholic acids and their glycine and taurine conjugates are reported. Exothermic enthalpies were found in each case. It is suggested that heat evolution is due to a bile salt-lecithin interaction other than hydrophobic in... | 430,495 | [
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Paired-ion reversed-phase high-pressure liquid chromatographic assay of pentobarbital-pyrilamine suppositories. | The assay of suppositories containing pentobarbital and/or pyrilamine in a water-soluble polyethylene glycol base by high-pressure liquid chromatography is described. No extraction is required. The suppository is dissolved in the mobile phase. This solution is diluted with an internal standard stock solution containing... | 430,500 | [
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Chemical reactions in cephalosporin allergy: high-pressure liquid chromatographic analysis of cephalosporin aminolysis kinetics. | Cephalosporin reaction with protein amino groups is fundamental to cephalosporin allergy. Cephalothin and cefazolin reaction kinetics with epsilon-aminocaproic acid, B-alanine, and glycine in aqueous solution were investigated. All reactions were conducted at 35 degrees and 0.5 ionic strength and were followed by ion-e... | 430,501 | [
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In vitro and in vivo availability of hydrophilized phenytoin from capsules. | The effect of phenytoin hydrophilization on the liquid penetration rate into prepared plugs, on the disintegration time, on the in vitro release rate, and on in vivo absorption in humans was studied. Hydrophilization was performed by intensive mixing of the hydrophobic drug with a small amount of methylcellulose soluti... | 430,506 | [
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... |
Radiochemical plasma salicylamide assay using ring-labeled tritiated salicylamide. | A rat plasma salicylamide assay was developed using ring-labeled tritiated salicylamide, synthesized by reacting salicylamide with tritium oxide in the presence of heptafluorobutyric acid. The reaction yielded 3H-salicylamide of specific activity up to 8.41 mCi/mmole, 60% yield. Plasma containing 3H-salicylamide and it... | 430,509 | [
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Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis Gray and Wikstroemia uva-ursi Gray (Thymelaeaceae). | The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva-ursi showed antitumor activity against the P-388 lymphocytic leukemia (3PS) test system One PS-active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringare... | 430,516 | [
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Help yourself to good health? | In recent years more support has been given to the idea of Health Education and there are strong reasons for believing that such schemes of prevention may receive much more financial backing from governments. It is being realised, also, that many of our 'ills' may be attributed to an over-reliance on medical technology... | 430,527 | [
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A follow-up neurobiological study: why volunteer? | There is usually great concern over the use of psychiatric patients for clinical research, as it raises the ethical and legal issues of human dignity and autonomy. In this paper the authors describe and evaluate a follow-up neurobiological study of patients who had been discharged from a psychiatric research ward at le... | 430,528 | [
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Departmental review in medical schools: focus and functions. | Approximately two-thirds of all U.S. and Canadian medical schools have provisions for the evaluation of their departments on a periodic or ad hoc basis. Most of these institutions have initiated the departmental review process since 1970. It appears that use of the practice is increasing and is becoming an important to... | 430,530 | [
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Age-related susceptibility of mice to staphylococcal infection. | The virulence of six strains of staphylococci in experimental subcutaneous infection in mice of three age groups (3, 10 and 21 days) was studied. The results showed an age-related susceptibility to infection, in that the newborn mice were more susceptible than older mice to death and lesion formation. Resistance, i.e.,... | 430,549 | [
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The mechanics of benign paroxysmal vertigo. | Benign paroxysmal vertigo (BPV) is a disorder of the vestibular labyrinth. The clinical features can be explained by an abnormality in the posterior semicircular canal. Under the influence of gravity, a density differential between the endolymph and the cupula will cause displacement of the cupula when changes in head ... | 430,582 | [
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Styloid, velar, and pharyngeal muscles in cleft palate. Anatomical findings in elderly cadaver with unrepaired cleft palate. | Dessection of the musculature of the palate, pharynx, and styloid process was carried out in a cadaver aged 78 years with an unrepaired complete cleft palate. A new muscle named "the accessory stylohyoid" was found to be attached to the styloid process and the lesser cornu of the hyoid bone bilaterally. Anatomical chan... | 430,584 | [
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Interruption-deficient mutants of bacteriophage T5 I. Isolation and general properties. | Mutations of bacteriophage T5 were isolated which lack one or more of the natural single-chain interruptions that occur in the mature DNA of this virus. Interruption-deficient mutants were detected by screening survivors of hydroxylamine mutagenesis for altered DNA structure by electrophoresis in agarose slab gels. Ove... | 430,606 | [
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Novel bacteriophage lambda mutation affecting lambda head assembly. | A novel phage lambda mutation, called dc10, which interferes with proper lambda head assembly has been isolated and characterized. Phage lambda carrying this mutation is (i) unable to form plaques at 30 or 37 degrees C but does so at 42 degrees C and (ii) unable to form plaques at 42 degrees C on pN-constitutive hosts.... | 430,610 | [
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Ultrasound-guided percutaneous nephrostomy in the pediatric patient. | Percutaneous nephrostomy drainage may be established rapidly using ultrasonic guidance in severely ill pediatric patients with obstructive uropathy. B-mode ultrasonography has proved to be rapid, accurate and free of irradiation hazards, making it applicable to children with little or no sedation. | 430,627 | [
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Satisfactions, dissatisfactions, and causes of stress in medical practice. | Careers of physicians who graduated from Case Western Reserve School of Medicine have been examined in several longitudinal career studies. Physicians have been interviewed in their own offices, have filled out short-answer questionnaires, and have taken four tests. Emphasis has been placed on factors that have made th... | 430,687 | [
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Depression in cancer patients. An approach to differential diagnosis and treatment. | Despite recent attention to death and dying, many questions remain about the diagnosis and treatment of depression in cancer patients. To provide a framework for effective treatment, this article distinguishes the following types of depression: (1) transient stress reactions, (2) major psychiatric disturbances requirin... | 430,688 | [
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Prenatal diagnosis of homozygous alpha-thalassemia. | A Vietnamese couple were both carriers of alpha-thalessemia-1. The woman had a first pregnancy terminated in the delivery of a hydropic fetus due to homozygous alpha-thalassemia. The couple requested prenatal diagnosis for the second pregnancy. The DNA obtained from cultured amniotic fluid cells was studied pregnancy. ... | 430,715 | [
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Pruritic urticarial papules and plaques of pregnancy. | We report an intensely pruritic cutaneous eruption that occurs in the third trimester of pregnancy. The clinical manifestations include erythematous urticarial papules and plaques that begin on the abdomen and spread to involve the thighs and occasionally the buttocks and arms. This dermatosis appears to be clinically ... | 430,731 | [
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Cardiac resuscitation in the community. Importance of rapid provision and implications for program planning. | Several time-related variables involving resuscitation from out-of-hospital cardiac arrest were studied. Short time intervals from collapse to initiation of cardiopulmonary resuscitation (CPR) and to provision of definitive care were significantly associated with survival from cardiac arrest. The two times were jointly... | 430,772 | [
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Occupational exposure to hexachlorocyclopentadiene. How safe is sewage? | In March 1977, a large volume of the industrial chemical hexachlorocyclopentadiene (HCCPD) was dumped into a municipal sewage system in Kentucky. We evaluated the health effects of exposure to HCCPD in 145 sewage treatment plant workers. We found that 85 (59%) had noted eye irritation, 65 (45%) had headaches, and 39 (2... | 430,818 | [
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Hyperpyrexia (temperature greater than 40 C) in children. | A total of 516 charts of children who presented to the Oklahoma Children's Memorial Hospital Emergency Department or Walk-In Clinic with a temperature of 40 C(104 F) or more were reviewed. The findings were consistent with the concept that high fever in children is most often associated with common illnesses such as up... | 430,938 | [
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Aspergillus flavus as a cause of thyroiditis in an immunosuppressed host. | Disseminated aspergillosis is a major complication in immunosuprressed patients. Infiltration of the thyroid with Aspergillus organisms occurs in approximately 20% of autopsies in patients dying with disseminated disease. The present report describes Aspergillus thyroiditis, Hashimoto's thyroiditis, and possible hypoth... | 430,949 | [
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[Characteristics of the course of ischemic heart disease in thyroid hypofunction]. | The peculiarities of lipid metabolism and hyperlipoproteinemia, blood coagulation and myocardial contractility in normal and reduced thyroid function were studied in 162 patients with ischemic heart disease. It was shown that hyperlipoproteinemia, hypercoagulation, and myocardial hypodynamia are revealed more frequentl... | 430,955 | [
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[Changes of refraction following operations with episcleral plugs and encircling procedures in cases of retinal detachment (author's transl)]. | Episcleral plugs reduce the circumference of the globe and cause an egg-shaped deformation; immediately after the operation the deformation seems to be more important than the circumference reduction. Out of 46 eyes operated on with episcleral silastic sponges or submitted to encircling procedures 3 developed hypermetr... | 431,011 | [
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[The application of highly hydrophilic contact lenses in the Fuchs-Steven-Johnson syndrome (author's transl)]. | In 3 patients with status after Fuchs-Steven-Johnson syndrome highly hydrophilic contact lenses (72% H2O-up take) were adapted and worn permanently. 2 patients had worn already for a long time usual HEMA-lenses. The lenses showed themselves to be favorable against mechanical irritation from cilia and accessory eyelashe... | 431,012 | [
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... |
[Patients on dialysis--late fundus controls (author's transl)]. | In 102 patients on dialysis for renal failure late fundus controls have been done to studie the response of retinal vessels to blood pressure reduction. In 52 patients follow up studies were possible. Only 4 patients showed reversible changes of the vessels, in 4 other patients changes increased. In the majority of the... | 431,018 | [
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[Strabogenesis in case of low hypermetropia, in addition a simple comparison test to detect aniseikonia (author's transl)]. | Author attempts to explain the rise of infantile convergent squint, when the hypermetropia is less than 3,5 diopter. In such cases the low hypermetropia is relative in the sense of Donders, because a sometimes isometropic aniseikonia prevents the fusion. To examine the aniseikonia he recommands a very simple procedure,... | 431,021 | [
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Endocardial alterations in myocardial infarction. | Transmural infarcts of the ventrolateral wall of canine left ventricle were produced by ligation of the ventral interventricular (anterior descending) branch of the left coronary artery. Endocardium from these infarcted hearts was sampled at sites corresponding to the infarct center and periphery, and to uninfarcted (n... | 431,037 | [
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Conducting tissues in univentricular heart of right ventricular type with double or common inlet. | Four specimens of univentricular hearts of the right ventricular type, three with two atrioventricular valves and one with a common valve, have been examined histologically to identify the atrioventricular conduction system. Three of the specimens were initially thought to have only one chamber within the ventricular m... | 431,104 | [
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Morphologic spectrum of Ebstein's anomaly of the heart: a review. | The rare and curious congenital malformation of the tricuspid valve known as Ebstein's disease or Ebstein's anomaly has been a subject of considerable interest to the cardiologist and the morphologist since its first description by Wilhelm Ebstein in 1866. With the evolution of various surgical techniques for the corre... | 431,123 | [
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Utilization review and containment for hospital utilization: some implications of providing care in the "most appropriate setting". | The study examines the potential for savings in the use of hospital resources if utilization review policies succeed in curtailing excessive use of hospital facilities. Excessive use is defined as the utilization of hospital care when ambulatory care is medically feasible and acceptable. A utilization review policy wou... | 431,144 | [
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0.04391687,
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0.06778613... |
Innovations: components of bundles. | Acceptance by target populations of new programs funded by government is a phenomenon which one should be able to explain with existing innovation theory. In a study of a newly formed group health practice, funded in part by OEO, it is found that a commonly used set of predictors has little utility in explaining indiv... | 431,150 | [
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[Vascular approach for periodic hemodialysis. Clinical course of 100 internal arteriovenous fistulas (author's transl)]. | The clinical course of 100 internal arteriovenous fistulas in patients observed over a period of more than 6 months was analyzed. Ninety-six were practiced in the upper extremities as side-to-side anastomoses in the forearm between the radial artery and the nearest vein; three were constructed in the lower limbs as ana... | 431,171 | [
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[Jadassohn's nevus sebaceus and nevus unius lateris. Report of an observation with multiple dysplasia (author's transl)]. | The case of a female patient with multiple ectodermal and mesodermal malformations present since birth is reported. The cutaneous lesions were of two types: Jadassohn's nevus sebaceus and nevus unius lateris. These entities have been described in the literature as congenital dermatologic alterations of nevoid character... | 431,172 | [
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[Myocardial infarction due to buckshot lodged in the right coronary artery (author's transl)]. | A rare case of myocardial infarction produced by a buckshot lodged in the right coronary artery is presented. It resulted from a shotgun blast aimed at the right side of the chest. The patient was admitted to an Intensive Care Unit in a state of shock 1 hour after the accident. The diagnosis was suspected from the firs... | 431,173 | [
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[Hepatic involvement in boutonneuse fever (author's transl)]. | Boutonneuse fever is a rickettsioses which is endemic in the Mediterranean countries. Since 1972 we have had the chance to study eight observations os this disease (6 in the last year) and our attention has been drawn by the constant hepatic involvement. This was biological in all cases and histopathologic in the five ... | 431,183 | [
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[Malignant hypereosinophilic syndrome. Report of an exceptional case (author's transl)]. | The case of a 43-year-old man with a highly malignant hypereosinophilic syndrome is reported. The condition is classified as such according to Hardy and Anderson's criteria, accepted by many other authors. Other diseases of known etiology which may present high levels of eosinophils in the peripheral blood, such as par... | 431,184 | [
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Hypertensive emergencies. | The clinical syndrome of accelerated hypertension is a relatively rare complication of hypertensive disease. The syndrome is recognized by high blood pressures, progressive neurologic and visual symptoms, acute renal damage, cardiac failure, and microangiopathic hemolytic anemia. When diagnosed, it must be recognized a... | 431,188 | [
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[Surgical treatment of early facial palsies in cases of longitudinal fractures of the temporal bone (author's transl)]. | Longitudinal fractures of the temporal bone are complicated by facial palsies in 10--25% According to the results of Fisch the lesions of the facial nerve are ever situated at the labyrinthine segment of the nerve. The most frequent lesion is the impression of bone fragments in the Fallopian canal. Clinical controls of... | 431,233 | [
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[Neurosurgical aspects of the treatment of acoustic neurinoma with special consideration of the facial nerve (author's transl)]. | The decisive progress in the field of surgical treatment of acoustic neurinomas has occured after the introduction of the operating microscope. This is a survey of the microsurgical treatment of cerebellopontine angle tumors with special emphasis of the facial nerve and demonstration of individual cases. Moreover, the ... | 431,239 | [
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Frequency and significance of epithelial atypia in laryngeal papillomatosis. | The clinical records and microscopic sections from 32 patients were reviewed in an attempt to correlate histopathologic features with clinical behavior. Three general clinical groups were identified on the basis of recurrence rates and extent of papillomatosis. In those lesions with the highest frequency of recurrences... | 431,255 | [
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[Electroureterograph and dynamoureterograph]. | The results of investigations made by the authors showed that the signal spectra of the bioelectrical and mechanical activity of the ureteral smooth muscles lie within the range of 0.05--1 Hz. The developed devices for registration of electro-and dynamograms of ureters may be utilized in investigating the functional st... | 431,361 | [
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[Possibility of increasing the efficiency of the apparatus for analysing the R-R intervals of electrocardiograms]. | To increase the operation speed of devices recording the R--R intervals on electrocardiograms, the authors performed a theoretical analysis of the differential-statistical method used for signal transformation, and elaborated a special block for p4-ch-0l electronic polygraph. Clinical trials confirmed the theoretical a... | 431,358 | [
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Xanthogranulomatous pyelonephritis (XGP): a local disease with systemic manifestations. Report of 23 patients and review of the literature. | The clinical, pathological and radiographic findings of 135 cases of xanthogranulomatous pyelonephritis have been reviewed. It is a form of renal suppuration and obstruction most commonly seen in middle aged women although all ages and both sexes may be affected. There is no race predilection. Gram-negative organisms a... | 431,402 | [
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Introducing students to the medical literature. | It is extremely difficut to determine if it really makes a difference to provide a medical journal to medical students. Does it alter their reading habits? Does it indeed form the basis for learning? In 1976 84% of the third year class and in 1972 69% (n=97), personally subscribed to a Journal designated. In the fourth... | 431,422 | [
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Monitoring and recording clinical trials. | A procedure based on the use of on-site monitoring has been developed for managing clinical testing programs. The procedure involves orientation meetings, forms specifically designed for good record-keeping, staff instruction, the establishment of normal laboratory values and criteria for patient selection, and prescri... | 431,427 | [
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Measurement of regional cerebral blood flow by intravenous injection of Xe133. | Clearance of Xenon 133 following intravenous injection has been used to perform atraumatic measurements of regional cerebral blood flow (rCBF). rCBF was computed by a two-compartmental analysis of the clearance curves associated with a correction for Xenon recirculation based on the end-tidal tracer concentration. Dire... | 431,507 | [
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[Sudden death due to unusual developmental anomaly of the coronary artery]. | In a case of the sudden death of a child, parents were suspected of negligence. At the autopsy anomaly of the coronary artery as the cause of severe damage to myocard and sudden death was revealed. | 431,542 | [
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Timing of oocyte maturation in the mouse and its relevance to radiation-induced cell killing and mutational sensitivity. | Timing oocyte development by labeling the zona pellucida indicates that it takes 6 weeks (possibly a few days more) for a stage 3b oocyte to reach ovulation. Thus the shift in mutation frequency with time after irradiation occurs in an oocyte stage that is comparable in all mammals so far investigated, and in the mouse... | 431,550 | [
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Evidence against transmission of Hodgkin's disease in high schools. | A survey in Greater Boston identified 1577 new cases of histologically diagnosed Hodgkin's disease between 1959 and 1973. Of these cases, 448 were of ages such that the patients might have attended high school during 1960-73. For 96 per cent of these persons high-school attendance was ascertained. First of all, we stud... | 431,594 | [
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Digoxin-quinidine interaction Pharmacokinetic evaluation. | Several recent reports have shown that plasma concentrations of digoxin increase when quinidine is administered along with digoxin; the present study was designed to explore the pharmacokinetics of this digoxin-quinidine interaction in six subjects. The elimination half-life of digoxin, although variable, did not chang... | 431,681 | [
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Construction of a site-specific, deletion-frameshift mutation in an essential gene of bacteriophage phiX174. | By in vitro methods, we have deleted 80 nucleotides from a preselected site in the coding sequence of gene G of bacteriophage phiX174. This mutant (Gdelta/FS ZH1) also carries a--2 frameshift. The mutation is lethal, but mutant virus can be stably maintained on host strains bearing plasmids carrying phiX gene G. | 431,717 | [
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Regional and sexual differences in the size of the neuro-vascular contact surface of the rat median eminence and pituitary stalk. | The size of the neuro-vascular contact surface was estimated along the median eminence (ME) proximal pituitary stalk (PS) of adult rats using serially cut 1 micrometer thick plastic sections. It was found 26% larger in female animals. The dorsal surface of the pars tuberalis was used as reference surface, and its size ... | 431,777 | [
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Possible linkage between alpha-haptoglobin (Hp) and depression spectrum disease. | Depression spectrum disease is an unipolar depressive illness in which at least one member of the family has unipolar depression and at least one other first degree relative has alcoholism and/or antisocial personality; using this definition, 14 depression spectrum disease families are studied. Assuming, among other th... | 431,798 | [
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[Importance of the analysis of the carcinoembryonic antigen in clinical oncology]. | 330 patients (126 with gastric neoplasms, 204 with large bowel carcinoma) were submitted to serial assays to evaluate the possible relations between C.E.A. levels, pathologic stage and histologictype of the neoplasm and to define the usefulness of the C.E.A. test in monitoring the followup of the patients with gastroin... | 431,843 | [
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[Automatic method for the evaluation of the extent of myocardial infarct from the serum of CPK curve]. | An off-line system for calculating the extent of infarct from serial serum CPK determinations based on Sobel et al.'s compartmental model is presented. Results in 40 patients with acute infarct in a coronary unit showed that the index of infarct extent had an appreciable prognostic significance. Employment of the MB is... | 431,862 | [
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Antidepressant drugs potentiate suppression by adenosine of neuronal firing in rat cerebral cortex. | Adenosine and AMP (5'-adenosine monophosphate) applied by microiontophoresis produced depression of neuronal firing rates in cerebral cortex. A number of antidepressant drugs including examples which are known not to affect noradrenaline uptake systems, potentiated the depressant purine effects. Noradrenaline responses... | 431,890 | [
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Bilateral trephine bone marrow biopsies in Hodgkin's and non-Hodgkin's lymphoma. | This study was undertaken to investigate the usefulness of bilateral rather than unilateral iliac trephine biopsies in demonstrating Hodgkin's disease and non-Hodgkin's lymphoma in the bone marrow. One hundred and seventy adequate bilateral biopsies were obtained from 145 patients. Among 76 bilateral trephine biopsies ... | 431,979 | [
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Enterocolitis due to Yersinia enterocolitica in South Australia. | From August 1976 to July 1977, all faecal specimens (3298) sent to the Enteric Department of the Institute of Medical and Veterinary Science, Adelaide were selectively cultured for Yersinia enterocolitica. Yersinia enterocolitica was isolated from three patients with diarrhoea, one of whom acquired her infection overse... | 431,980 | [
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-0.2865869,
-0.08073349,
-0.1842881,
0.00299988,
-0.01234931,
0.0941544,
0.1744218,
0.01343623,
-0.1215667,
-0.4130602,
-0.4846772,
0.03276901,
-0.1530044,
-0.07896286,
0.01125069,
0.42225,
-0.16557... |
Congenital ureteral valve. | A one year old boy with ureteral obstruction due to congenital ureteral valve is presented. This rare lesion is usually diagnosed pre-operatively as ureteral stricture or primary megaureter. | 431,994 | [
-0.1643166,
-0.08103553,
-0.416421,
-0.04172029,
0.1478129,
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0.2491052,
0.3384532,
0.535935,
0.002903599,
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-0.3467748,
0.1746679,
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-0.3924877,
0.2776487,
0.0902532,
-0.1218615,
... |
Parathormone and perinatal calcium homeostasis. | Plasma parathormone (PTH) and calcium concentrations were measured in 309 specimens collected from 190 newborns during the first 7 days of life. The patient material consisted of 51 preterm, 130 term, and 9 postterm infants, including 22 infants of diabetic mothers (IDM), 38 infants with hypocalcemia, and 25 asphyxiate... | 431,996 | [
-0.4573377,
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0.2134131,
0.008503119,
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0.4215735,
0.204976,
0.03124082,
-... |
Basal and pentagastrin-stimulated acid secretion in newborn human infants. | Basal and pentagastrin-stimulated gastric acid secretion was measured in 26 healthy newborn infants on the 1st and 2nd days of life. Basal acid outputs (BAO) on day 1 (0.378 mEq/hr) and day 2 (0.388 mEq/hr) were similar and not significantly different from the maximal acid outputs (MAO) on day 1 (0.413 mEq/hr) and day ... | 432,000 | [
-0.3181078,
-0.4829186,
-0.560365,
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0.002657099,
0.002079444,
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0.008867774,
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0.2677137,
0.5486997,
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0.1685742,
-0.002146314,
0.2444585,
0.4763317,
0.2535897,
-0.01145... |
Recalibration of the convergence system. | Adaptation to convergence-altering prism spectacles was studied. The subjects were trained for 8 min with either convergence-increasing or convergence-decreasing prisms. Before and after training they estimated the distance to a binocular dot varying in the stimulus it provided to convergence. Both the preadaptation an... | 432,078 | [
-0.1847838,
0.09162777,
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0.1230659,
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0.03677732,
0.256005,
0.05165203,
0.214308,
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0.2679772,
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-0.05695649,
-0.0687962,
0.05758683,
... |
Frequency, phase, and colour coding in apparent motion. | We present some results which indicate that the known spatiotemporal limits for apparent motion are consistent with the motion being sinusoidal or a result of filtering. Given this we investigated how two such motions interact as a function of their relative temporal phase differences. This was accomplished by inducing... | 432,081 | [
-0.1065247,
0.2756957,
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0.02871891,
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0.227912,
-0.009090183,
-0.097... |
[An information system for a department of nuclear medicine (author's transl)]. | A computer system is connected on-line to each working place of a department for nuclear medicine. It is assisting the daily work such as the measuring and processing of the measured data, the medical interpretation of the results and the finding of the diagnosis, and finally the composing and writing of medical report... | 432,108 | [
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0.04232968,
0.2953341,
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0.2174806,
0.02974722,
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0.04325912,
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0.3313943,
0.4839508,
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-0.1105504,
0... |
Genetic causes and workup of male and female infertility. 1. Prenatal reproductive loss. | Studies show that the greatest check on human reproduction occurs prenatally in apparently fertile couples. Most chromosomally abnormal embryos are aborted spontaneously. This paper, to be published in three parts, reviews the major known anatomic, functional, genetic, and environmental causes of infertility and reprod... | 432,156 | [
-0.01038754,
0.01729475,
-0.02801348,
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0.1228861,
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0.1950803,
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0.2590706,
0.2649857,
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0.09042181,
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0.003851572,
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0.02339929,
0.4445511,
-0.1... |
[Ultra-violet spectrophotometry in drug control. Part 23: Conclusions from the spectrophotometric behaviour of drugs with pyridine, naphthalene, quinoline and isoquinoline chromophores (author's transl)]. | The results from a systematic study of drugs with pyridine, naphthalene, quinoline and isoquinoline chromophores are evaluated and condensed into conclusions. In addition to previously reported findings, the ultra-violet and visible spectra of a further nine drugs containing the mentioned chromophores are presented. | 432,253 | [
-0.1566714,
0.2261444,
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0.08741156,
0.1275758,
0.08401588,
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0.3353965,
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0.3907676,
0.5050385,
-0.1347723,
-0.113371... |
Stability of acetylsalicylic acid in divided powders in the presence of aminophenazone. | The combination of acetylsalicylic acid with aminophenazone, often prescribed in divided powders, is considered to be incompatible. High performance liquid chromatography was applied to determine the content of salicylic acid which is the main known product from the decomposition of acetylsalicylic acid. The analysis o... | 432,254 | [
-0.2820197,
0.3629369,
-0.03577281,
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0.2138863,
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0.5914449,
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0.09658767,
0.01909294,
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0.1239136,
-0.2554195,
-0.02999103,
-0.1185577,
0.3061619,
0.4920183,
-0.1092474,
-0.1438... |
On Ce, Clambda, and the effective wall material of a Baldwin-Farmer chamber. | An expression relating the constant A to the characteristics of an ionisation chamber is developed. This constant, used to obtain the mass ionisation from the instrument reading, appears in expressions for Ce and Clambda, and is a function of the chamber wall material. Measurements with a Baldwin-Farmer chamber are des... | 432,271 | [
-0.01239793,
0.4151425,
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0.162406,
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0.06803402,
0.1762673,
0.41671,
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-0.2697093,
-0.08634226,
0.04096365,
0.3068555,
0.3950255,
0.2681552,
0.02045343,
0.3... |
Continuing education: an attitudinal survey of physical therapists. | A descriptive study of 903 physical therapists located primarily in southeastern United States was undertaken to determine their attitudes toward continuing education and the types of course offerings they desired. A majority of physical therapists kept themselves up-to-date in professional practice, mainly through dis... | 432,278 | [
-0.1000962,
-0.2086908,
0.200603,
-0.07307057,
0.2137076,
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0.04609983,
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0.1251729,
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0.2882777,
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-0.4008208,
-0.06042619,
0.3082901,
-0.1672796,
0.03704... |
[Use of the Doppler for intrafemoral injection in arteritis]. | The discovery of a femoral artery that is clinically non palpable can be made using the Doppler. It is thus possible to use a direct intra-arterial treatment. This is what was done by the authors, who thereby divided the patients into two groups: the first, 22, with non palpable femoral arteries; the second, 20, with p... | 432,292 | [
-0.4110138,
0.03783157,
-0.08174255,
0.1486915,
0.03953482,
-0.2777789,
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0.09103912,
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0.01462327,
-0.1995898,
0.1853572,
-0.2190092,
-0.2834266,
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-0.2235326,
0.1461736,
-0.06818964,
0.2768515,
-0.02794282,
-0.02261643,
-0.01541... |
Social interactions, communications, and the coronary-prone behavior pattern: a psychophysiological study. | Sixty subjects classified as either Type A or Type B interacted in pairs by pressing buttons which transmitted messages through a television screen while the heart rate and digital blood volume pulse were computer-monitored. Partners could cooperate, compete, punish, reward, or withdraw on each interaction and could se... | 432,360 | [
-0.2373233,
0.6117011,
-0.09965471,
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0.02413104,
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0.1186558,
0.04493061,
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0.203664,
0.364704,
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0.01458146,
-0.3807088,
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0.6783534,
0.1240529,
0.2466467,
0.03316065,
-0.0288189,
-0... |
Human antirabies treatment in the United States, 1972. | Data were examined on 965 persons treated in six States (Delaware, Florida, Georgia, Illinois, North Dakota, and South Carolina) and New York City in 1972 for possible rabies exposure. Males 10-19 years were found to be the group at greatest risk, and exposures occurred most frequently during the warm months. Dogs, oth... | 432,411 | [
-0.234714,
-0.2369744,
-0.3674179,
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0.00863651,
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0.1147319,
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0.2999169,
0.2177715,
0.2471799,
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0.205881,
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0.2815591,
0.1007833,
0.007862943,
0.4590382,
-0.281432,
0.... |
Light-evoked changes in chick optic lobe adenylate-cyclase. | The effects of exposure to 48 h darkness and to stroboscope stimulation on chick optic lobe adenylate-cyclase activity were studied. A significant decrease in adenylate-cyclase after 48 h exposure to darkness occurred with return to normal values after re-exposure to light. Stroboscope stimulation for 3 min produced in... | 432,431 | [
0.04559792,
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0.1245419,
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0.02449839,
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-0.09741298,
0.2735341,
0.3173857,
0.05044... |
Brain sulfatide and non-lipid sulfate metabolism in hypothyroid rats. | Neonatal hypothyroidism reduced the concentration of sulfatide in myelin and synaptosomes isolated from brains of 20-21 day old rats. The in vivo incorporation of 35SO4 into sulfatide of myelin, microsomal, animals, as was the incorporation of the isotope into non-lipid sulfate (sulfated glycoproteins and mucopolysacca... | 432,433 | [
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0.09689297,
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-0.1706971,
-0.04258467,
-0.1328402,
0.001246424,
0.1145157,
-0.00... |
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