title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Eccentric serous choroidopathy: a case report. | A patient presented with a serous detachment of the retina outside the macular region in one eye and three years later a similar detachment in the fellow eye. The clinical findings were otherwise identical to those seen in patients with idiopathic central serous choroidopathy. Idiopathic eccentric serous choroidopathy ... | 455,123 | [
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The surgical management of macular pucker. | Contractions of collagenous membranes in the posterior cortical vitreous may produce macular pucker and loss of central vision. It is possible to separate these membranes from the retina, and if one succeeds in doing so there is reasonable improvement in central visison. Between December 1976 and September 1978, six pa... | 455,125 | [
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The nasal step in normal and glaucomatous visual fields. | We used an original method of kinetic and static analysis to examine the nasal visual field. When the nasal step is less than 4 degrees wide and its depth is less than 0.5 log units it may be merely a physiological sign of the anatomic and functional asymmetry of the retina. Sometimes it is an artifact. The nasal step ... | 455,132 | [
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CAGS lecture. Scientific salients in surgery. | Surgery, as a field of clinical skill and scientific knowledge, advances by Discovery, Development and Delivery. While the basic biosciences have been more productive in Discovery than have the clinical fields, surgery has participated in several important areas of Discovery. Developmental science is often called biome... | 455,163 | [
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A prognostic study of urothelial renal pelvic tumors: comparison between the prognosis of patients treated with intrafascial nephrectomy and perifascial nephroureterectomy. | A comparison of the prognosis between 2 series of patients with urothelial renal pelvic tumors is presented. One series comprising 70 patients was operated with intrafascial nephrectomy with extirpation of varying length of the ureter. The other series comprising 38 patients was operated with transabdominal perifascial... | 455,238 | [
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Cancers of the large bowel: associated disorders in individuals. | The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associa... | 455,240 | [
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Hodgkin's cells and attached lymphocytes: a possible prognostic indicator in splenic tumor. | After the purification of Hodgkin's cells by a previously reported method from splenic tumor of 8 patients with Stages III or IV Hodgkin's disease, we have examined the proportions of Hodgkin's cells with attached lymphocytes. All patients were studied 3--5 years after staging laparotomy. Four patients had no recurrent... | 455,243 | [
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Childhood bronchial mucoepidermoid tumors: a case report and review of the literature. | A bronchial mucoepidermoid tumor in a 13-year-old female was studied by light and electron microscopy. This is the seventh reported case of this rare bronchial neoplasm in a person less than 16 years of age and the only case, in any age group, which has been studied ultrastructurally. All reported cases of bronchial mu... | 455,258 | [
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Rapid determination of methylated purines in DNA treated with N-methyl-N-nitrosourea using high-performance liquid chromatography. | A method for determining methylated purine bases in [3H]N-methyl-N-nitrosourea (MeNOUr) treated DNA is described. The method combines reversed-phase high performance liquid chromatography (HPLC) of methylated DNA after hydrolysis in dilute acid with the determination of radioactivity in the fractionated eluates. The pe... | 455,269 | [
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Photodynamic inactivation of cancer cells in vitro. Effect of irradiation temperature and dose fractionation. | Human cancer cells in vitro (NHIK 3025), derived from a carcinoma in situ are inactivated when exposed to visible light in the presence of hematoporphyrin. Irradiation at 4 degrees C results in much more efficient inactivation than irradiation at 37 degrees C. Furthermore, a given total light dose is more efficient whe... | 455,270 | [
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Effect of L-alpha-amino-gamma-guanidinobutyric acid on melphalan therapy of the L1210 murine leukemia. | About half the mice administered a lethal inoculum of L1210 leukemia become 60-day survivors when treated with an appropriate dose of melphalan. Leucine completely abolishes this long-term survival by interfering with melphalan uptake into the tumor cells. L-alpha-Amino-gamma-guanidinobutyric acid, the lower homolog of... | 455,272 | [
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Chromosomal DNA cytophotometry in 20q- nonspecific myeloid disorders. | DNA cytophotometry was used to quantify the chromosomal alterations in the bone marrow and blood of three patients with nonspecific myeloid disorders. All patients possessed a population of cells with a morphologically abnormal chromosome 20, del(20)(qll). In two of the patients, the abnormal chromosome 20 showed nearl... | 455,284 | [
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Phase II study of cis-dischlorodiammineplatinum(II) in stage IVB Hodgkin's disease. | A broad phase II study of cis-dichlorodiammineplatinum(II) was conducted. Eight patients with stage IVB Hodgkin's disease were studied. Four of these patients attained an objective partial remission of 7--19+ weeks' duration. The usual time to the occurrence of a greater than 25% response was 1 week. This drug is activ... | 455,312 | [
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Nucleus praeopticus and nucleus lateralis tuberis of Salmo salar and Salmo gairdneri: structure and relationship to the hypophysis. | The nucleus praeopticus (NPO) is located on both sides of the preoptic recess and is composed of a pars parvocellularis and a pars magnocellularis. Only in the rainbow trout does the pars magnocellularis consist of separately located medium-sized cells and very large cells. Cytologically, three cell types can be distin... | 455,395 | [
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Lysosomal breakdown of erythrocytes in the sheep placenta. An ultrastructural study. | The breakdown of erythrocytes within the lysosomal apparatus of trophoblastic epithelial cells of the sheep placenta was studied at the ultrastructural level. Acid phosphatase activity could be demonstrated in the interspace between the erythrocyte membrane and the lysosomal membrane, but not inside ingested erythrocyt... | 455,403 | [
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A correlated scanning and transmission electron microscopic study of maturation ameloblasts in developing molar teeth of rats. | Maturation ameloblasts of developing molar teeth of the rate were studied by both scanning and transmission electron microscopy. After fixation, teeth were frozen and split. One face of the fractured tooth was used for SEM, the other for TEM. It was found that in some regions proximal junctional complexes separate the ... | 455,407 | [
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Autoradiographic studies of a glucocorticoid agonist and antagonist: localization of 3H-corticosterone and 3H-cortexolone in mouse brain. | The localization in the mouse brain of corticosterone, the natural glucocorticoid in the mouse, and cortexolone, reported to be a glucocorticoid antagonist, was studied by autoradiography 30 min after in vivo administration of the tritiated compounds. After 3H-corticosterone (3HB) injection, radioactivity was preferent... | 455,413 | [
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Deletion mutants of Xenopus laevis 5S ribosomal DNA. | Deletion mutants have been derived from a plasmid-cloned repeating unit of Xenopus laevis oocyte 5S DNA by introducing the transposable chloramphenicol-resistance element Tn9 into the AT-rich spacer sequence near the 5' terminus of the X. laevis 5S rRNA gene in a recombinant plasmid and then selecting plasmids which ha... | 455,442 | [
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Four T7 RNA polymerase promoters contain an identical 23 bp sequence. | The DNA sequences of four promoters for the bacteriophage-specified T7 RNA polymerase have been determined. All four regions contain an identical 23 bp sequence 5' pTAATACGACTCACTATAGGGAG-A(oh) which includes the 17 bp prior to and the first 6 bp of the transcribed region. They are located at 46.5, 55, 57 and 87% on th... | 455,451 | [
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Sequence analysis of adenovirus DNA: complete nucleotide sequence of the spliced 5' noncoding region of adenovirus 2 hexon messenger RNA. | The complete nucleotide sequence of the 5' noncoding region of the adenovirus 2 hexon messenger RNA has been established by sequence analysis of reverse transcripts. Such transcripts were generated by extension of specific single-stranded DNA primers with reverse transcriptase after hybridization to purified hexon mRNA... | 455,452 | [
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Reiteration frequency of the gene coding for the small subunit of ribulose--1,5--bisphosphate carboxylase. | The messenger RNA coding for the precursor of the small subunit of ribulose--1,5--bisphosphate (Ru-P2) carboxylase has been partially purified from pea leaves. The mRNA has a size of 11.5S, is approximately 800 nucleotides long and, on cell-free translation, directs the synthesis of a single major polypeptide of 20,000... | 455,470 | [
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Synthesis, properties and reactions of 3 beta-benzoyloxy-7 alpha-15 beta-dichloro-5 alpha-cholest-8(14)-ene. | Treatment of 3 beta-benzoyloxy-14 alpha,15 alpha-epoxy-5 alpha-cholest-7-ene (I) with gaseous HCl in chloroform at -40 degrees C gave, in 87% yield, 3 beta-benzoyloxy-7 alpha,15 beta-dichloro-5 alpha cholest-8(14)-ene (III). Reduction of the latter compound with lithium aluminum hydride in ether at room temperature for... | 455,568 | [
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Evaluation of cardiac activity and pharmacokinetic analysis of 3H-adriamycin in patients pretreated with beta-methyldigoxin. | The consequences at the cardiac level of adriamycin treatment alone or in association with the cardiac glycoside beta-methyldigoxin, were evaluated with reference to the PEP/LVET ratio, heart rate, and minimum blood pressure. The variation usually seen in the PEP/LVET ratio when adriamycin is administered alone was not... | 455,570 | [
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Some effects of chemotherapeutic drugs on bone marrow stem cells. I. The long-term effects of phase-specific drugs on mouse bone marrow stem cells. | Two phase-specific drugs, cytosine arabinoside and hydroxyurea, were studied with regard to their effects on various murine hematologic cell compartments of the same mouse. Effects of single and multiple injections of Ara-C were compared. Following a significant decrease in the first few days, and a subsequent overshoo... | 455,575 | [
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Performance assessment of the GammafloTM automated radioimmunoassay system by assaying for digoxin. | We report an evaluation of the GammafloTM automated continuous-flow radioimmunoassay instrument in which we used a digoxin assay to assess system performance. System operation was based on combined continuous-flow and column-chromatographic techniques. No drift or carryover was detectable in 180 within-assay consecutiv... | 455,646 | [
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Diabetic ketoalkalosis. | The usual metabolic derangement in uncontrolled diabetes mellitus is metabolic acidosis, with an increase in the anion gap because of increased ketoacids and lactate. However, diabetic ketoalkalosis may occasionally be encountered, the prominent clinical feature of which is vomiting, with depletion of potassium, chlori... | 455,654 | [
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Assay of plant sterols by use of cholesterol oxidase. | The cholesterol esterase/cholesterol oxidase enzyme kit can be used for analysis of plant sterols. The results are comparable to those obtained by conventional colorimetric analysis. | 455,687 | [
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EEG's in an alcohol detoxification and treatment center. | EEG's were carried out on two hundred and one (201) alcoholics admitted to a four week treatment program. The majority were grossly intoxicated on admission and presented the usual differential problems during the first few days of hospitalization. In spite of therapeutic doses of medication before testing, 85% had tot... | 455,734 | [
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0.2422125,
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-0.2894749,
0.1064995,
-0.07528228,
0.1496018,
-0.1444915,
-0.2618785,
0.4809742,
-0.2510013,
0.5431767,
-0.3330994,
0.3328708,
0.1622229,
0.03069076,
-0.3444619,
0.324395,
-0.08347445,
-... |
Effect of the angiotensin II antagonist saralasin on plasma aldosterone concentration and on blood pressure before and during sodium depletion in normal subjects. | The effect of the angiotensin II antagonist saralasin on plasma aldosterone, plasma angiotensin II and blood pressure was studied in six normal supine subjects both before and during sodium depletion. Before sodium depletion, infusion of saralasin produced no consistent changes; during sodium depletion, infusion of the... | 455,738 | [
-0.05865265,
0.03507632,
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0.1844755,
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0.02989837,
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0.05660498,
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0.1901196,
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0.07630704,
-0.018275... |
The mediation of the localization of polymorphonuclear leucocytes in glomeruli during the autologous phase of nephrotoxic nephritis. | A passive model of the autologous phase of nephrotoxic nephritis (NTN) in rabbits was developed to study the events at the initiation of this stage of the disease. Intravenous injection of sheep anti-rabbit glomerular basement membrane antiserum was followed 48 hr later by 125I trace labelled rabbit anti-sheep IgG. Ani... | 455,777 | [
-0.04972394,
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0.006104178,
0.2268871,
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0.1680069,
0.01612452,
0.10211,
0.3940304,
0.4146851,
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-0.09... |
Diagnosis of ruptured bladder during a 99mTc-DTPA renal study: new indications for radionuclide cystography? | Radionuclide cystography, which is currently used to evaluate vesicoureteral reflux, has also been used to detect perirenal and perivesical urine leakage. We report a case of intraperitoneal bladder rupture and describe potential indications and advantages of cystography for detection and evaluation. | 455,858 | [
-0.3007385,
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0.07309018,
0.1159829,
0.0008226133... |
Legg-Calvé-Perthes disease: Results of discontinuing treatment in the early reossification phase. | The major controversy in Legg-Calvé-Perthes disease concerns its treatment. All authors recognize the need for containment of the femoral head but do not agree on the method of containment. Surgical containment is constant, does not require an endpoint for discontinuing treatment and has a short treatment period. Conse... | 455,854 | [
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0.5114144,
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0.06290824,
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0.111289,
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0.3010074,
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Myositas ossificans progressiva associated with severe scoliosis. | This is an 11 year follow-up of a patient with myositis ossificans progressiva and severe scoliosis, an association that seems not to have been reported previously. A progressive increase of the curve occurred even after maturity. Early instrumentation and fusion should be considered on any similar case, with excision ... | 455,849 | [
-0.2219326,
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0.03082652,
0.4767359,
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-0.1... |
S-C joint disruption in an infant. | An anterosuperior sternoclavicular disruption in a 7 month old female was caused by trauma. Good results were observed by concervative managment. | 455,853 | [
-0.2905715,
0.006110996,
-0.03557933,
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-0.232692,
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0.05815363,
0.05776591,
0.1322229,
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-0.2954415,
-0.08754608,
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0.03622992,
0.2691834,
-0.1110784,
0.093229... |
The multi-channelled pylorus. | The entity of multiple pyloric channels may be congenital but the majority are acquired lesions representing fistulae secondary to peptic ulcer disease in the pyloroduodenal region. The fistula usually joins the lesser curvature of the stomach with the superior aspect of the duodenal bulb. The multichannelled pylorus p... | 455,909 | [
-0.1883957,
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0.1714875,
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0.1227748,
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0.07067865,
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0.3144802,
-0.03437489,
-0.229237... |
Allergy to lanolin. | The purpose of the present study was to compare the frequency of lanolin allergy during two periods and to assess the adequacy of testing with one standard allergen. Among 1230 consecutive patients with eczema who were standard patch tested, 33 (2.7%), 21 females and 12 males, gave a positive reaction to wool alcohols.... | 455,960 | [
0.08443147,
0.281135,
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0.2134935,
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-0.154753,
-0.008679696,
-0.1324775,
-0.08710... |
Does occupational exposure to glass-fibres increase the general skin reactivity to irritants? | A total of 33 workers at a glass-wool factory were tested (patch tests with glass-fibres and chemical irritants, epicutaneous tests with Trafuril and intracutaneous tests with histamine) before starting to work at the factory and then re-tested after at least 4 weeks of exposure to glass-fibres. No statistically signif... | 455,965 | [
0.1549239,
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0.1065003,
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0.0942584,
0.06260106,
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0.003205774,
0.1685289,
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0.135227,
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0.2486576,
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-0.0110711,
-0.0763438,
0.4414178,
0.230127,
-... |
The use of a contraceptive vaginal ring governed by the pattern of individual uterine bleeding. | Contraceptive vaginal rings (CVR) releasing levonorgestrel and estradiol were used for contraceptive purposes in eight women. They were instructed to remove the CVR for five days only, in the case of bleeding. Three selected subjects were followed by plasma sampling during the first 60 days of treatment. Plasma concent... | 455,988 | [
-0.06233451,
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0.2804029,
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0.1278264,
0.6389406,
0.290738,
0.05363169,
... |
Hematological and biochemical values of thoroughbred foals in the first six months of life. | Hematological and biochemical parameters in five Thoroughbred foals during the first six months of life are reported. The samples were analyzed for red blood cell, packed cell volume, hemoglobin, platelet, white blood cell, absolute number for leukocytes, and erythrocyte fragility and serum calcium, inorganic phosphoru... | 455,991 | [
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0.2180194,
0.2968075,
0.09070859,
0.3121444,
-0.483336,
-0... |
Staff attitudes towards the care of the critically ill in the medical intensive care unit. | In an attempt to study the basis for conflict and tension surrounding decision making in ICU settings, a questionnaire was used to examine staff attitudes in a newly opened medical ICU in four major areas: (1) ethical issues; (2) decision-making process; (3) communications; and (4) emotional reactions of staff. All of ... | 455,996 | [
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0.1479945,
0.003314402,
0.1517286... |
Acute renal failure after ruptured abdominal aortic aneurysm: an improved clinical prognosis. | Eleven cases of renal failure associated with resection of ruptured abdominal aortic aneurysm and requiring hemodialysis are reported. Previously described series have emphasized the extremely high mortality rate in such patients. In our clinical experience, however, 8 of 11 consecutively treated patients with this cli... | 456,000 | [
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0.06955208,
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0.3198972,
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Early retransfer: a method of optimal bed utilization of NICU beds. | To facilitate increased utility of Neonatal Intensive Care Unit (NICU) beds, we adopted a policy of early discharge (ED) of infants less than 2000 g to the hospital of their birth after recovery from acute illness and when the infant was breathing room air and taking adequate oral feedings. An inservice teaching progra... | 456,009 | [
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0.3512801,
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0.0348005,
0.1564868,
0.01052... |
Verrucous ulcerative skin lesions in sarcoidosis. An unusual clinical presentation. | A twenty-seven year old man with a two year history of sarcoidosis and systemic manifestations of this disease along with verrucous ulcerative skin lesions is presented. Biopsy specimens of the cutaneous lesions showed typical noncaseating granulomas as well as necrotizing granulomatous inflammation. After other possib... | 456,024 | [
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-0.06844905,
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0.2805125,
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0.02850534,
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0.1606983,
0.4053133,
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-0.05012655,
0.1782937,
-0.1647... |
Infection with hair transplant surgery. | The problem of infection during hair transplant surgery in one dermatologist's office is described herein. Careful epidemiologic investigation identified the causative organism and its source, and the infection was effectively controlled by the use of "semi-sterile" technique. Infection may be more common than generall... | 456,033 | [
0.1142851,
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0.1208903,
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0.3316167,
0.0043377... |
Fatal pulmonary hemorrhage in Henoch-Schönlein purpura. | An unusual case of an eight year old boy with Henoch-Schönlein purpura in whom fatal pulmonary hemorrhage developed resulting from leukoclastic vasculitis of the lungs is presented herein. | 456,038 | [
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0.06977677,
0.04201757,
0.4329661,
0.1788279,
0.049950... |
Diagnostic accuracy in peripheral lung lesions. Factors predicting success with flexible fiberoptic bronchoscopy. | Ninety-seven consecutive peripheral lung lesions were evaluated by biplane fluoroscopically guided flexible fiberoptic bronchoscopy and analyzed to define features that predict diagnostic yield. The overall diagnostic accuracy was 56 percent (63 percent for malignant and 38 percent for benign lesions). The most importa... | 456,057 | [
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0.2876107,
0.3545257,
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0.3730826,
0.03133773,
-0.2222206,... |
Pharmacokinetics of cefadroxil in normal subjects and in patients with renal insufficiency. | Pharmacokinetics of cefadroxil, a new orally semisynthetic cephalosporin, was studied in 5 subjects with normal renal function and in 20 patients with varying degrees of renal insufficiency. All subjects received 1,000 mg per os in a single dose and the elimination phase was studied. In healthy subjects, elimination ha... | 456,077 | [
-0.0734129,
0.004459565,
-0.3140461,
-0.2084026,
0.133732,
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-0.306195,
0.287578,
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0.1457346,
0.2045863,
0.4559368,
0.08663759,
0.0... |
Child welfare management: a model curriculum. | A social work school curriculum designed especially to train persons to manage child welfare program is in its second year of operation. It may provide a model for training personnel in this area. | 456,090 | [
-0.2282159,
0.09525785,
-0.0585204,
-0.3176219,
0.07329602,
-0.3108172,
-0.1255112,
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0.1167743,
-0.03500731,
-0.138794,
0.06303576,
-0.03747125,
0.1547727,
-0.0975... |
Hydrocephalus in myelomeningocele. | 156 children born with myelomeningocele were studied over a 3- to 10-year follow-up period. The appearance, type and rate of development of hydrocephalus were noted and correlated with the findings on neonatal and follow-up physical examination. 80% of the children developed overt hydrocephalus; 73.4% of these cases we... | 456,113 | [
0.02167599,
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0.06091692,
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0.3202202,
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0.5266139,
-0.004857203,
-0.1410653,
0.2823032,
-0.09650034,
-0.09201807... |
[Preoperative detection of antrum mucosa in patients with peptic ulcer following gastric secretion -- indication for reintervention?]. | In 6 of 23 patients with marginal ulcer after gastric resection (B II and Roux-Y anastomosis) a retained ("excluded") gastric antrum attached to the duodenal stump was detected by 99mTC pertechnetate scintiphotography; serum gastrin levels were normal in two of those cases. Resection has been abandoned as a treatment m... | 456,115 | [
-0.1377763,
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-0.2320242,
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0.1874194,
-0.3060023,
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0.2874537,
0.3569596,
0.1084273,
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-0.234941,
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0.06825916,
0.1036148,
0.3922837,
0.09677249,
-0.1383498,
... |
[Role of histamine in acute pancreatitis]. | Elevated histamine concentrations of pathophysiological significance could be determined in plasma of dogs suffering from acute pancreatitis according to Pfeffer. This result was also obtained in dogs treated with aminoguanidine, a very effective diamine oxidase blocker, in addition to the duodenal blind loop preparati... | 456,138 | [
0.03686753,
-0.05944384,
-0.09402579,
-0.09860928,
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-0.2492203,
0.1949987,
-0.09716027,
-0.1086766,
-0.1417977,
0.09379709,
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-0.0117271,
-0.1167397,
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-0.3496301,
0.2685401,
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0.05863971,
-0.02628011,
-0.1413178,
-0.0... |
[Reaction of the liver cells to surgical intervention in obstructive jaundice. Electron microscopic-morphometric studies of the rat liver]. | In Wistar rats, bile was drained by biliocutaneous fistulas 7 days after ligation of the common bile duct. Morphometric analysis using a computer program registered about 60 parameters of a hepatocyte. Most cell organelles are again normal 7 days after intervention. The ultrastructural changes are not fully compatible ... | 456,140 | [
0.33482,
-0.06271389,
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0.3062303,
0.01172446,
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-0.04234143,
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0.2910648,
0.1700754,
0.1897118,
-0.01734065,
0.1649633,
-0... |
[Myocardial metabolic status in various methods of inducing a reversible heart arrest]. | In experiments with dogs, three different methods of inducing a reversible cardiac arrest were compared: (A) the ischemic arrest for 45 min, (B) the cardiac arrest for 90 min due to injection of Cardioplegin according to KIRSCH, and (C) the cardiac arrest for 90 min due to infusion of solution LK 352 according to BRETS... | 456,143 | [
-0.2921319,
0.0155261,
-0.3488641,
-0.8077741,
0.3949994,
-0.2577806,
-0.2506622,
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0.08031666,
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0.5241392,
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0.2137229,
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-0.3358885,
-0.1159283,
0.2997304,
0.3351547,
0.04936159,
-0.1429675,
... |
[Significance of the complement system in acute pancreatitis in rats]. | The influence of complement system in acute pancreatitis in the rat was examined. Two different experimental procedures were used to induce pancreatitis: distal choledochal ligature and the Pfeffer model as modified by NEVALAINEN. In both procedures an acute pancreatitis developed and complement depression was noted. T... | 456,145 | [
0.259782,
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0.1203985,
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0.3537575,
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-0.1621185,
... |
[Comparative studies on pulsatile and continuous flow during extracorporeal circulation. Effects on liver function and endocrine pancreas secretion]. | The effects of pulsatile and nonpulsatile flow pattern on pancreas and liver blood flow were studied in nine dogs on cardiopulmonary bypass (CPB). Furthermore, plasma levels of glucose, insulin, glucagon, growth hormone, and cholinesterase were compared in 20 patients subjected to open heart surgery with either pulsati... | 456,149 | [
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0.02775881,
0.1038308,
0.238374,
-0.256809,
-0.04811511,
0.... |
[Effects of bacterial peritonitis on the low-pressure system in man]. | The effective compliance (C) of the "low-pressure system" has been measured in ten patients with bacterial peritonitis by means of plotting pressure and volume on the first postoperative day (deltaV = 500 ml/10 min). The value of C is decreased in one group of patients, while it increases to as much as five times that ... | 456,151 | [
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0.04217334,
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0.07447467,
-0.07461697,
0.1054578,
-0.3978194,
-0.08593258,
0.2059941,
-0.6959935,
-0.3971446,
-0.3104421,
0.08042683,
-0.1144438,
0.2680863,
0.121038,
-0.01508844,
0.1188023... |
[Pharmacological modification of regional blood flow in rat stomach mucosa]. | The effect of three agents with antisecretory function on regional gastric mucosal blood flow was measured using the microspheres technique. Salbutamol caused a significant decrease in blood flow, while DMPGE2 caused a significant increase. After calcitonin no change was observed. This is contrary to the belief that in... | 456,153 | [
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0.3949725,
0.5151302,
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0.06841... |
[Cancer of Vater's ampulla]. | From 1964 to 1977 a total of 50 patients were operated on for carcinoma of the ampulla of Vater, the second most frequent tumor of the periampullar region. The cardinal symptom was jaundice. The diagnostic procedures of high value were roentgenographic examination of the upper gastrointestinal tract with the use of bar... | 456,176 | [
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0.5279515,
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0.273... |
Effects of griseofulvin on mitosis in PtK1 cells. | The concentration dependent effects of griseofulvin (GF) on mitosis in PtK1 cells were studied using a combination of time lapse cinematography and polarization and electron microscopy. Low concentrations of GF (4 X 10(-5) M) allowed a substantial number of cells to enter and complete an apparently normal mitosis. At h... | 456,199 | [
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0.1010315,
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Underreplication of a polytene chromosome arm in the chironomid Prodiamesa olivacea. | The genome of Prodiamesa olivacea (Diptera, Chironomidae) has a 2 CDNA content of 0.25 pg. Mitotic metaphases reveal 3 pairs of chromosomes: 2 metacentric ones and one submetacentric. The latter comprises 20.8% of total Feulgen DNA. During larval polytenization the complemental portion of the 3rd falls to 6.5%. Concomi... | 456,201 | [
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... |
Ecdysone-induced changes in Glycoprotein synthesis and puff activities in Drosophila virilis salivary glands. | During five hours after the injection of alpha-ecdysone into the hemolymph of D. virilis late third instar larvae the formation of larval glycoproteins in the salivary glands is terminated and the synthesis of a different set of glycoproteins which is characteristic for the prepupal gland is initiated. The data present... | 456,202 | [
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0.3491901,
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0.1841... |
Comparison of flexible sigmoidoscopy with other diagnostic techniques in the diagnosis of rectocolon neoplasia. | Flexible sigmoidoscopy was compared to rigid sigmoidoscopy in the detection of colorectal neoplasia in a select group of patients. A distance of 30 cm or greater was obtained by flexible sigmoidoscopy in 94% of patients and a distance of 50 cm or greater in 46% of patients. A significant number of cancers and adenomas ... | 456,214 | [
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0.4300328,
0.001255137,
0.110... |
Lack of supportive evidence for an autosomal recessive inheritance in chronic hepatitis B infections. | Two families with persistent hepatitis B infections are described. The patterns of HBsAG positivity in the parents and offspring are not compatible with the theory that susceptibility to chronic hepatitis B infection is inherited as an autosomal recessive trait. | 456,216 | [
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0.02... |
Pancreatic duct arteriovenous fistula and the metastatic fat necrosis syndrome. | This report summarizes the course of a patient with asymptomatic chronic pancreatitis associated with hemorrhage into the pancreatic duct and metastatic fat necrosis. Retrograde cannulation of the pancreatic duct and superior mesenteric arteriography established the presence of a pseudocyst with a pancreatic duct-arter... | 456,226 | [
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-0.4679776,
... |
Peyronie's disease and sclerosing cholangitis in a patient with ulcerative colitis. | A 51-year-old patient with a 30-year history of ulcerative colitis developed sclerosing cholangitis and later Peyronie's disease. The occurrence of these diseases in the same patient supports the view of an immunological origin of these associated disorders. | 456,234 | [
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0.1570142,
-0.0105514... |
A syndrome of acute self-limiting ulcerative esophagitis in young adults probably due to herpes simplex virus. | Five healthy young adults developed an acute self-limiting ulcerative esophagitis. Two had definite evidence of herpes virus being present and a third one had appropriate changes in herpes simplex viral titer. All cases followed a characteristic and similar course consisting of sudden onset of odynophagia, multiple dis... | 456,240 | [
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... |
Bioassay and radioimmunoassay of serum luteinizing hormone in the male rat. | Measurements of immunoactive and bioactive serum LH in the rat were performed after optimization of both RIA and rat interstitial cell-testosterone (RICT) assay to measure the low circulating LH levels of intact male rats. The effective sensitivity of the RIA was increased 3- to 5-fold to 6.2 or 4.7 ng RP1/ml by extrac... | 456,316 | [
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0.2680782,
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-0.... |
A method for designing peptide substrates for proteases. Tripeptidyl-p-nitroanilide substrates for subtilisin Carlsberg. | 1. The kinetic parameters of 25 peptidyl-p-nitroanilide substrates were investigated with subtilisin Carlsberg as model enzyme. 2. For a series of 12 substrates, the contribution of various side chains to the affinity constant was computed by regression analysis. From these contributions the sequence of a new and bette... | 456,343 | [
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0.2855815,
0.5933859,
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-... |
Conformational energy calculation on the peptide part of murein. | Conformational energy calculations have been carried out on N-acetyl-L-alanyl-D-gamma-glutamyl-L-lysyl-D-alanyl-D-alanine as a model of the peptide moiety of peptidoglycan. Although many conformations were of comparable energy, particular favoured conformations were selected by assuming conformational similarity betwee... | 456,347 | [
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-0.03143906,... |
Construction in vitro of hybrid plasmids carrying all the EcoRI fragments from lambdarifd18 DNA. | The cloning of all the eleven fragments obtained by degrading the phage lambdarifd18 by the restriction enzyme EcoRI into the plasmid pSF2124 has been achieved: nine of these fragments have been cloned individually, whereas two others have been cloned jointly in the same plasmid. These fragments harbor, in addition of ... | 456,358 | [
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0.09924877,
0.2829561,
0.005754236,
-0.113... |
Synthesis of albumin and malic enzyme in wheat-germ lysates and Xenopus laevis oocytes programmed with chicken-liver messenger RNA. | Undegraded, biologically-active, polyadenylated RNA was isolated from chicken liver by a rapid, simple procedure. Liver cells were dispersed mechanically and then broken gently by controlled Dounce homogenization in the absence of detergent or ribonuclease inhibitors. After removing lysosomes and mitochondria by centri... | 456,360 | [
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... |
The phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus. Complete tyrosine assignments in the 1H nuclear-magnetic-resonance spectrum of the phosphocarrier protein HPr. | Upon nitration of the phosphocarrier protein HPr three nitrated derivatives of the protein were isolated: mononitrated HPr, dinitrated HPr and trinitrated HPr. Tryptic digestion of the derivatives leads to nitrotyrosine-containing peptides which were isolated and characterized by amino acid analysis. This resulted in t... | 456,367 | [
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0.2201571,
0.1888509,
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0... |
Base crystallization and base stacking in water. | 2H2O solutions of 6-methylpurine and N6,N9-dimethyladenine have been examined by neutron diffraction. Comparison of the scattering from various molar solutions of 6-methylpurine with the scattering from its crystalline precipitates indicated base stacking in solution with a separation of approximately 0.34 nm. In parti... | 456,369 | [
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0.5785438,
-0.0001117791,
-0.059325... |
DNA-protein interactions in nucleosomes and in chromatin. Structural studies of chromatin stabilized by ultraviolet-light induced crosslinking. | Crosslinking induced by ultraviolet light irradiation at 254 nm has been utilized to investigate the structure of chromatin and isolated nucleosomes. The results presented here imply that the four core histones, as well as histone H1, have reactive groups within a bond length of the DNA bases. In nucleosomes depleted o... | 456,371 | [
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0.1293403,
0.3865344,
0.1879758,
-0.1580003,... |
Terbutaline and adrenaline inhibit leakage of fluid and protein in guinea-pig lung. | The effect of terbutaline (0.3 mg/kg s.c.) and adrenaline (0.1 and 0.3 mg/kg s.c.) on histamine--aerosol-induced increase in lung weight and dye content was studied in conscious guinea pigs, previously given Evans blue dye. Both drugs prevented the effects of histamine. It is concluded that terbutaline and adrenaline h... | 456,417 | [
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0.02170756,
0.2039812,
... |
Alteration of GABA metabolism in mammalian brain by l-alpha-amino-beta-chloropropionic acid hydroxamide and related compounds. | The administration of L-alpha-amino-beta-chloropropionic acid hydroxamide (L-ACPH) to mice brought about an inhibition in GABA-T activity in the brain of the animals, a significant inhibition occurring with dosage levels as low as 0.25 mmol/kg. Minimum levels of GABA-T activity were reached 3 h after administration of ... | 456,423 | [
-0.2834637,
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0.6719798,
0.06397682,
0.4535804,
-0.01929967,
-... |
Remarriage after divorce: dissolution and reconstruction of family boundaries. | Remarriage is analyzed from the perspective of family boundaries and roles. The nuclear and remarriage family models are compared, and the process that begins with the formation of the first-marriage nuclear family and ends with the formation of a second-marriage family is conceptualized in terms of changing family bou... | 456,501 | [
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0.3239023,
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0.09733194,
0.0... |
The brain renin-angiotensin system: a critical analysis. | The concept of a brain renin-angiotensin system originated with the observation that the components necessary for the formation of angiotensin II are present in the central nervous system. This observation has been confirmed and extended, and it is now frequently assumed that there is a functional brain renin-angiotens... | 456,611 | [
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0.3399239,
-0.03715596,
0.009427013,
-0.06580749... |
[Effect of strychnine and picrotoxin on the development of habituation in the visceral analyzer]. | Effects of strychnine and picrotoxin on habituation of cortical potentials evoked by repeated stimulation of the splanchnic nerve were studied in anesthetized and immobilized cats. I. v. administration of strychnine (o.1 mg/kg) or picrotoxin (0.4 mg/kg) did not alter the decrement in evoked potentials. Larger doses of ... | 456,637 | [
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0.2882001,
0.4752451,
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0.1925098,
0.016396... |
[Coding visual information in frogs by means of the latent periods of neuronal responses]. | The difference between latencies of responses of the retina ganglionic cells and the neurons of the midbrain tectum in frogs seems to be a way of coding visual signals which indicates the probability of the coherent principle of visual information processing. In combination with the probability-statistical principle, t... | 456,644 | [
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0.353925,
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... |
[Analysis of focal potentials in the cat cerebral cortex during activation of cerebello-thalamo-cortical projection systems]. | Peculiarities of topographical distribution of responses of the cat cerebral cortex to stimulation of cerebellar and thalamic (ventro-lateral and ventral anterior) nuclei as well as cerebello-thalamo-cortical projection system and comparison between the cerebellar and thalamic responses revealed differences in focal po... | 456,677 | [
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0.1975999,
0.09005745,
... |
The changing impact of white migration on the population compositions of origin and destination metropolitan areas. | Increased migration to the sunbelt and the metropolitan-nonmetropolitan "turnaround" represent departures from long-standing redistribution trends. Although these patterns have been examined from a number of perspectives, their consequences for individual metropolitan areas have not yet been brought to light. In the pr... | 456,703 | [
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0.3717737,
-0.04345344,
... |
Motivations for the inmigration component of population turnaround in nonmetropolitan areas. | Data from a 1977 survey of metropolitan and nonmetropolitan origin households migrating to 75 high net inmigration counties of the Midwest are examined to consider the motivational basis for the inmigration component of post-1970 nonmetropolitan migration trends. Findings suggest that the major stated motivations for l... | 456,704 | [
-0.283024,
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0.1823457,
0.08736275... |
Effects of dependency among causes of death for cause elimination life table strategies. | A study is made of the effects of associated causes of death, and of dependency among causes of death, by observing the relative importance of one cause of death when another is eliminated under various competing risk models. Two disease pairs, cancer and infectious disease and stroke and ischemic heart disease, are se... | 456,707 | [
-0.2516547,
-0.236376,
0.01703357,
0.07589799,
0.4114154,
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0.08279055,
0.1103814,
0.1641437,
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0.3263734,
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0.03504438,
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-0.2198565,
0.1564657,
0.2202861,
0.3518967,
-0.1551089,
0.... |
Within-species variation in the development of ultrasonic signaling of preweanling rats. | The development of litter and individual differences in the rate of ultrasonic signaling of neonatal rats was studied. Systematic variations among litters and individuals emerged, without differential treatment. These differences were not correlated with variations in general development as indexed by body weight. Two ... | 456,751 | [
0.2275927,
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0.2750334,
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0.1383707,
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-0.3614829,
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-0.1768568,
-0.2107189,
0.07152919,
0.1088209,
-0.1715129... |
Do 16-week-old infants anticipate stimulus offsets? | Twenty alert 16-week-old infants were presented with 20-sec tones at variable intertrial intervals for 10 trials while beat-by-beat heart rate responses were recorded to assess response at offset as well as onset of each stimulus. Consistent with past research, onsets elicited deceleratory responses which habituated an... | 456,759 | [
-0.1534576,
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0.08155347,
0.08357234,
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0.322407,
0.1632042,
-0.182591,... |
Ligation or external fistulation of the common bile duct in the rat. I. Intestinal sucrose hydrolysis and absorption in vivo. | 72 h after ligation of the common bile duct in the rat the sucrose hydrolysis in vivo was greater than in sham-operated animals, whereas the absorption of the split products, glucose and fructose, was not altered. In bile-depleted rats the sucrose hydrolysis did not differ from that in the control group. The absorption... | 456,766 | [
0.138794,
0.0830752,
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0.05553049,
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... |
[The demand for blood in open-heart surgery (author's transl)]. | Because of the continous increase of utilization of open heart surgery, whenever possible a more conservative use of blood is desirable. During 1977, 262 consecutive patients were operated upon using the hemodilution technique of cardiopulmonary bypass. Thirtyone operative deaths occurred (11.8%) and were not related t... | 456,801 | [
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0.571732,
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0.07252194,
0.2644028,
0.6883464,
0.05663111,
-0.0167... |
[Lidocaine administration in a patient with Wolff-Parkinson-White syndrome and atrial fibrillation (author's transl)]. | This report describes a case of Wolff-Parkinson-White syndrome with atrial fibrillation in which the ventricular complexes conducted over the accessory pathway have promptly disappeared with the use of intravenously administered lidocaine. Lidocaine is suggested as the most suitable drug in such situations. Finally pos... | 456,804 | [
-0.1941934,
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0.3911051,
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0.08520161,
0.5648351,
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0.2025724,
0.1315252,
-0.08033448,
0.2080715,
-0.01751919,
-0.0345... |
Diagnosis of emphysematous cholecystitis by computerized tomography. | A case of emphysematous cholecystitis is presented in which computerized tomography helped to confirm the diagnosis and the extent of disease preoperatively. This unusual disorder is briefly reviewed and the clinical and radiographic findings are discussed. | 456,829 | [
-0.1349033,
-0.03143288,
0.02053504,
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0.2738244,
0.09154508,
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0.197819,
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0.2671049,
0.09393666,
-0.259238,
0.107282,
-0.02105746,
-0.073936... |
Gas-forming intrahepatic abscess: a possible complication of arterial infusion chemotherapy. | Three cases of intrahepatic gas-forming abscesses are presented with liver metastases and indwelling hepatic artery catheters for drug infusion. This may represent a further complication of intrahepatic arterial drug infusion. Possible etiologies along with future prospects for this form of therapy are discussed. | 456,830 | [
-0.2863428,
0.02194059,
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0.001510106,
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0.08208196,
0.1255671,
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0.2974887,
0.04197521,
0.09391627,
0.1216962,
-0.06167997,
0.0430... |
Selective mesenteric phlebography in patients with carcinoid tumors. | Seventeen patients were investigated to localize carcinoid tumor growth in the small intestine and liver. Portography, selective phlebography of the intestinal veins, arteriography, and hormone assay (Serotonin, substance P) after simultaneous catheterization of the celiac artery and portal and caval veins were perform... | 456,834 | [
-0.01907141,
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0.1773844,
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0.4157662,
0.3105955,
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0.1896388,
0.2291094,
0.3747616,
-0.02839008,
-0.0657414,
... |
[Experience with long-term intra-uterine devices (author's transl)]. | At the hospital for women in Finkenau intra-uterine devices are used since 1965. At first plastic devices were used exclusively. It was assumed that the devices could stay for variable times. The present opinion that non-commper deivces have to be changed at regular intervals is in contradistinction to our first opinio... | 456,860 | [
-0.1448812,
0.07799151,
0.0008943154,
0.1720742,
0.1561737,
-0.2457943,
-0.1241313,
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0.4299749,
0.3696125,
0.07083974,
-0.3867983,
0.0684947,
0.0697014,
-0.3601146,
-0.3184043,
-0.3454882,
0.1165485,
-0.2861314,
-0.3646015,
0.3407169,
0.3112276,
0.004504427,
... |
["Teratologic series" and their genetics]. | Isolated cyclopia is one of the members of the prosencephalic teratologic series. In some families with cyclopian monster other types of prosencephalic malformations are found in sibs or more distant relatives. All these malformations occur more frequently in females. Different forms of prosencephalies are observed in ... | 456,891 | [
-0.1336737,
-0.07625025,
-0.01946044,
-0.1301861,
0.5128507,
-0.2543623,
-0.4893759,
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0.07660265,
0.2032254,
0.236189,
0.181833,
0.1354741,
-0.07400879,
-0.3615159,
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-0.5697253,
0.2236008,
0.2315674,
-0.04630995,
0.3385804,
0.1687195,
-0.2626565,
... |
Age-related changes of the pattern of non-histone chromatin proteins from rat and mouse liver chromatin. | The non-histone chromatin (NHC) proteins which are loosely bound to DNA were extracted from young and old mouse and rat liver chromatin by 0.35 M NaCl and fractionated into three groups: water-soluble, 0.14 M NaCl soluble and 0.35 M NaCl soluble. NHC proteins in each fraction were separated by SDS-disc polyacrylamide g... | 456,894 | [
-0.050825,
0.09997332,
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0.06245681,
0.1875028,
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0.1713362,
0.08491711,
0.1054716,
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0.2441712,
0.1705955,
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0.07531585,
0.2797638,
0.05531993,
0.007765937,
0.114381,
-0.1189845,
... |
Distribution of type A and type B monoamine oxidase activity in hypothalamic nuclei of the rat. | The regional distribution of type A, type A and B and type B activity of monoamine oxidase (MAO) in individual nuclei of the rat hypothalamus was studied according to quantitative micromethods with clorgyline as a specific inhibitor of type A MAO. As results, type A and type B MAO were distributed differently in the ra... | 456,952 | [
0.1758581,
0.1334768,
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0.02320022,
0.1384182,
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0.03859613,
0.239058,
0.1433107,
0.2232949,
0.3240407,
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0.1665184,
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0.4232703,
0.2717099,
0.1646326,
0.2424814,
0.1573521,
0.1552847,
0.0472725... |
An autopsy case of multiple leucoencephalitis showing hemiatrophy of the brain. | A 39-year-old female died 25 years after the onset of epileptic seizure. In the clinical course, she suffered epileptic seizures, left hemiparesis and muscular atrophy of the left upper extremity, psychological character change, dementia, forced laughter and hallucinatory and delusional states. Pathologically, severe c... | 456,958 | [
-0.1772293,
0.1551025,
-0.05954046,
-0.1650456,
0.3329099,
-0.4066969,
-0.0561484,
0.08545645,
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0.08256449,
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0.3178999,
0.06325608,
0.2535799,
0.1222876,
0.207001,
-0.371746,
0.2668706,
-0.1589244,
-0.09927938,
-0.1662738,
0.4565667,
-0.09034941,
... |
Paroxysmal dysesthesia in multiple sclerosis. | Seven cases of multiple sclerosis with paroxysmal dysesthesias of an upper extremity were reported. This seizure characteristically is a purely sensory one induced by movements and is not accompanied by convulsions or a disorder of voluntary movements. In other ways it shares some features with other paroxysmal manifes... | 456,960 | [
-0.1457569,
0.009529981,
-0.1396771,
-0.2457258,
0.1567889,
-0.3818373,
-0.2648042,
-0.3512077,
-0.0681401,
-0.2116789,
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0.2247551,
0.01847413,
-0.04643652,
0.1233628,
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-0.3237131,
0.0918304,
-0.02799418,
-0.220013,
-0.03560075,
0.2788159,
0.108146,
... |
Definitions of ischaemia, infarction and necrosis. | Definitions of the terms ischaemia, infarction and necrosis are presented and their significance in connection with sudden cardiac death is discussed. Morphological features of acute myocardial fibre degeneration are reviewed and the significance of such findings are considered. | 456,965 | [
-0.3054699,
0.01077412,
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0.01190883,
0.05686049,
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0.1369499,
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0.1737701,
0.1613968,
0.07979461,
-... |
[Clinical transcutaneous measurement of oxygen pressure during the induction of anesthesia with barbiturates]. | Intravenous injection of barbiturates is followed by a depression of the respiratory centre depending on the dose. Blood carbon dioxide increases. This can be measured continuously in the expired air. In the same time blood oxygen modifies. The hypoxia produced by this depressant action was determined by a non-invasive... | 456,983 | [
-0.2449201,
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0.1335579,
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0.03075669,
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0.02777613,
0.1968884,
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-0.284771,
0.24821,
0.09347101,
0.1900143,
-0.1077541,
-0.03984685,
0.2011012,
... |
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