title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Serum IgE levels in Chagas' disease. | Elevated levels of serum immunoglobulin E are found in many parasitic diseases caused by helminths. We have previously demonstrated that giardiasis was not associated with hyperimmunoglobulinaemia E. In order to determine the influence of Trypanosoma cruzi on IgE levels of clinically symptomatic patients, a controlled ... | 101,314 | [
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Cell-mediated immune responses in owl monkeys (Aotus trivirgatus) with trachoma to soluble antigens of Chlamydia trachomatis. | The first temporal study of the cell-mediated immune responses (CMI) following ocular infections with Chlamydia trachomatis is presented. We examined the CMI of owl monkeys infected with trachoma to soluble antigens of C. trachomatis by leucocyte migration inhibition (LIF) and delayed hypersensitivity skin testing. Del... | 101,327 | [
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Disturbance of cage-finding in the monkey. | Qualitative and quantitative observations were made on two monkeys with unilateral or bilateral removals of areas 5 and 7 of Brodmann. The task was to return to the home cage in the light or in the dark. Both animals were slower in the dark, and also qualitatively abnormal in the light. | 101,348 | [
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Heat-shock DNA homology in distantly related species of Drosophila. | Polytene chromosomes of D. melanogaster and D. virilis were hybridized in situ with 125I labeled mRNA isolated from polysomes of D. melanogaster tissue culture cells incubated at 37 degrees C. 125I mRNA hybridized preferentially with subdivisions 87A and 87Cl of the D. melanogaster 3R chromosome; grains were also obser... | 101,363 | [
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Ribosomal subunits from Tetrahymena pyriformis. Isolation and properties of active 40-S and 60-S subunits. | Tetrahymena pyriformis ribosomal subunits were obtained by incubation of post-mitochondrial supernatant in the presence of 0.2 mM GTP and 0.1 mM puromycin for 45 min at 28 degrees C, followed by sucrose density gradient centrifugation. Isolated 40-S subunits were able to reassociate in vitro in the presence of 5 mM MgC... | 101,371 | [
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Electron microscopic studies on the macronuclear development in the ciliate Chilodonella uncinata. | The development of macronuclear anlage in the ciliate Chilodonella uncinata has been studied through electron microscopy. The ultrastructure of macro- and micronuclei is described for comparison. During the first stage of development, when the DNA content of the macronuclear anage increases from 2 C to 32 C, chromosome... | 101,400 | [
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Role of nonagglutinating antibody in the protracted immunity of vaccinated mice to Pseudomonas aeruginosa infection. | Effective immunization against infection with Pseudomonas aeruginosa is difficult to evaluate because agglutinin levels decline rapidly. Because fractionation of hyperimmune sera often yields more specific antibody than can be accounted for by direct agglutination tests, an immunoglobulin-specific assay based on antigl... | 101,467 | [
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Effects of iron and culture filtrates on killing of Neisseria gonorrhoeae by normal human serum. | Neisseria gonorrhoeae GC9, both colony types T2 and T4, were killed by normal human serum, although populations of colony type T4 were more susceptible. Ferric ammonium citrate prevented the killing of populations of both T2 and T4 colony types. Other iron compounds tested showed no protective effect, nor did ammonium ... | 101,468 | [
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Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection. | The smooth lipopolysaccharide complex of the outer surface of smooth Brucella abortus cells is believed to be the antigenic component involved in serological tests routinely used for the diagnosis of brucellosis. Sera from cattle vaccinated or infected with B. abortus generally contain antibody directed toward the smoo... | 101,470 | [
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Chronic pyelonephritis. An electron microscopic study in nonhuman primates. | The rhesus monkey (Macaca mulatta) proved to be a successful model for the ultrastructural study of ascending nonobstructive pyelonephritis. The most severe kidney damage occurred where the inflammatory response was greatest, and these areas overlaid a dilated or clubbed calyx. The most prominent ultrastructural change... | 101,481 | [
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Methylene blue and other agents as inhibitors of calcium oxalithiasis in vivo. | Growth of calcium oxalate on an established calculus upon a zinc nucleus in the bladder of rats was studied. Animals were fed either a regular solid chow or chow containing a potential crystal inhibitor ad libitum, along with drinking water containing 0.75 per cent ethylene glycol. Chow containing 0.2 per cent methylen... | 101,482 | [
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Isolation of ekatetrone, a new metabolite of producing variants of Streptomyces aureofaciens. | From a mixture of substances formed by producing strains of Streptomyces aureofaciens under conditions of submerged fermentation a new metabolite, ekatetrone, was isolated. Its isolation and basic physical and chemical data are described. Ekatetrone is a quinone derivative with a carboxamide group. In tests in vitro wi... | 101,501 | [
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Independence of Bacillus subtilis spore outgrowth from DNA synthesis. | The outgrowth of spores of Bacillus subtilis 168 proceeded normally in temperature-sensitive DNA mutants under restrictive conditions and in the absence of DNA synthesis. Two inhibitors of DNA synthesis, nalidoxic acid and 6-(p-hydroxyphenylazo)-uracil, inhibited spore outgrowth under some nutritional conditions; this ... | 101,508 | [
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Physiological and morphological observations on Thiovulum sp. | Cell suspensions of Thiovulum sp., collected from enrichment cultures, were grown, maintained, and harvested for periods up to 7 months. In open-flow cultures run with aerated seawater, a continuous supply of hydrogen sulfide was provided by diffusion through a semipermeable membrane from either a live culture of Desul... | 101,531 | [
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Monkey pepsinogens and pepsins. III. Carbohydrate moiety of Japanese monkey pepsinogens and the amino acid sequence around the site of its attachment to protein. | Purified Japanese monkey pepsinogens I and II contain carbohydrate as a part of the enzyme molecule. By gel filtration on Sephadex G-100, chromatography on DE-32 cellulose, and polyacrylamide disc gel electrophoresis, the carbohydrate moiety could not be separated from the enzyme protein, and the content did not decrea... | 101,535 | [
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Characterization of the Bacillus subtilis bacteriophage PBS2-induced DNA polymerase and its associated exonuclease activity. | The DNA polymerase induced by Bacillus subtilis bacteriophage PBS2 has a Stokes radius of 7.2 in buffers of high ioninc strength, suggesting a molecular weight in the range 145,000 to 195,000. The polypeptide bands observed on gel electrophoresis in dodecyl sulfate have apparent molecular weights of 78,000 and 69,000 (... | 101,539 | [
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Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. | A high molecular weight glycoprotein consisting of three disulfide-linked 142,000 molecular weight chains has been isolated from human blood platelets. The glycoprotein, designated thrombospondin, is released by platelets in response to thrombin treatment and is proteolyzed when left in the presence of platelets after ... | 101,549 | [
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Screening for mild hypertension: costs and benefits. | It is important to understand the full implications of introducing a new screening and treatment programme into the National Health Service. In this paper, we calculate, for mild hypertension, the cost of community-based screening and the cost of case-finding in general practice. We show that case-finding in general pr... | 101,569 | [
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Admission and adjustment of residents in homes for the elderly. | This paper discusses the relationship between psychological variables, a brief cognitive measure and a behavioural rating scale, and the subsequent adjustment of a group of elderly people newly admitted to a social services home for the elderly. It shows that, in this sample, three groups can be identified: a fairly in... | 101,570 | [
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Squirrel monkey temporary threshold shift from 48-h exposures to low-frequency noise. | Five squirrel monkeys were exposed for 1, 2, 4, 8, 16, 24, and 48 h to a 375--750-Hz band noise at an overall SPL of 95 dB. The TTS4.5 growth pattern for the 750-Hz test frequency was biphasic and did not reach an asymptote after 48 h of exposure. For all exposures, the mean thresholds of the five monkeys returned to w... | 101,572 | [
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A study of the effect of slow-reacting substances of anaphylaxis on the rhesus monkey airway. | Slow-reacting substance of anaphylaxis (SRS-A) generated from rat peritoneal mast cells was aerosolized to the airways of a group of rhesus monkeys with established airway responses to ascaris antigen. A selective effect of SRS-A on pulmonary resistance and a lesser but significant effect on compliance was observed whi... | 101,573 | [
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Behavioral and dermatologic changes and low serum zinc and copper concentrations in two premature infants after parenteral alimentation. | Two premature infants were observed to develop behavioral and dermatologic changes and low serum zinc and copper concentrations following cessation of prolonged parenteral alimentation, while being fed exclusively with human milk. Following treatment with exogenous oral zinc supplementation, prompt relief of symptoms a... | 101,647 | [
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Growth response of the marine blue-green alga, Gomphosphaeria aponina, to inorganic nutrients and significance to management of Florida red tide. | A bioactive isolate from the blue-green alga Gomphosphaeria aponina is cytolytic towards the dinoflagellate, Gymnodinium breve, Florida's red tide organism. Batch and continuous cultures of G. aponina were used to determine nutrient limitation and to optimize mass-culture conditions. Iron and inorganic carbon were grow... | 101,740 | [
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[The diagnostic value of ejaculate cultures in acute unspecific epidiymitis (author's transl)]. | Bacteriological cultures of the ejaculates of 28 patients with acute unspecific epididymitis yielded in 6 cases growth of organisms which were considered to be the cause of the disease. Tests with conventional clinical antibiotics showed organism resistance in half of these cases. Because of possible contamination of t... | 101,777 | [
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Drug resistant tuberculosis in New Zealand. | Strains of M. tuberculosis resistant to one or more of the antituberculous drugs have not been common in New Zealand in the past. There is however, a high incidence of drug resistant tuberculosis in Western Samoa, 50 percent of cultures tested showing drug resistance and half of these are resistant to two or more drugs... | 101,915 | [
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The response of the living organism to dead and fixed dead enclosed homologous tissue. | Polyethylene tubes at both ends and with four perforations in the side walls were filled with untreated homologous necrotic muscle tissue or formaldehyde-fixed or glutaraldehyde-fixed homologous necrotic tissue and implanted subcutaneously in rats. The cell reaction in the tissues surrounding the differently filled tub... | 101,928 | [
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Residues of pesticides and PCBs in estuarine fish,1972-76--National Pesticide Monitoring Program. | This report summarizes 1524 analyses of juvenile fish collected semiannually in 144 estuaries nationwide from July 1972 through June 1976. Pooled samples of 25 whole fish were screened for 20 common pesticides and polychlorinated biphenyls (PCBs). The three most common residues, DDT, PCBs, and dieldrin, were found in 3... | 101,966 | [
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Undersea psychophysiologic reactions of human organism. | The determinations carried out on 12 divers during the immersion into the sea to a depth between 7 and 29 m, as well as on controls in immersions at 4 m revealed a significant prolongation of the visual reaction time and a marked tachycardia. The changes were more marked at great depths and if exercise was superimposed... | 101,994 | [
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0.050532,
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0.5429854,
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0.235451,
0.07287592,
0.1934305,
-0.334372,
-0.24... |
Arachidonic acid distribution in lipids of mammary glands and DMBA-induced tumors of rats. | In the phospholipid fractions, arachidonic acid represented a several fold higher percentage of fatty acids from DMBA-induced tumors and in mammary glands from midpregnant rats when compared to mammary glands from virgin rats. Arachidonic acid was not present in measurable quantities in the neutral lipid fractions of m... | 102,001 | [
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0.3115924,
-0.07789914,... |
[Peroral nitrate therapy in severe cardiac insufficiency following acute myocardial infarct]. | Ten patients with severe congestive heart failure after acute myocardial infarction were treated with 40 mg isosorbiddinitrate-retard every 4 hours and additional sublingual nitroglycerine. There was a prompt improvement of hemodynamic parameters which was maintained for 24 hours: pulmonary capillary wedge pressure (PC... | 102,029 | [
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0.109255,
0.11431... |
[Preoperative localization of myocardial areas requiring revascularization in coronary artery disease (author's transl)]. | At the time of preoperative coronary angiography in 44 patients left ventricular angiograms immediately after high frequency stimulation and after administration of nitroglycerin were performed. For interpretation we used the shortening (in percentage) of 8 vertical semi-diameters and of longitudinal axis in biplane an... | 102,047 | [
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0.09935236,
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-... |
Long-term short hemodialysis-implications to dialysis index. | From this data, we conclude: 1) that dialysis therapy should be individualized to achieve optimal patient well-being; 2) that long-term hemodialysis for 8--12 hr/wk with 1.0--1.5 M2 coil dialyzers and 1.3--2.5 M2 Dow Cordis hollow fiber kidney is feasible and safe; 3) that most patients do well on hemodialysis, when DI... | 102,059 | [
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0.4100484,
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[Spontaneous formation of angiogenic woven bone within cancellous bones. Some observations on microfractures of isolated trabecula (author's transl)]. | Femoral heads removed for subcapital fracture of the femur were embedded in methacrylate. Contact roentgen films of slabs of 1--2 mm thickness were screened for aggregates of woven bone. A variety of form exceeding that seen by other methods was found, not only in association with isolated trabecula. The distribution w... | 102,093 | [
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0.1613307,
... |
Platelet survival determination in atherosclerosis. | Platelet survival presently represents a useful method for the study of atherosclerosis and its consequences in patients and in animal models. The currently used technique, while time consuming, appears to be reliable and reproducible for the measurement of platelet survival and turnover rate. The test offers promise t... | 102,122 | [
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The application and limitations of immunodiagnostic techniques in parasitic infections. | The application of immunodiagnostic techniques in the diagnosis of parasitic infections has been discussed in relation to the conditions operating in developing countries where multiple parasitism is common and diagnostic facilities are often limited. The uses and limitations of the tests for individual diagnosis and e... | 102,136 | [
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Coronary, ventricular, and pulmonary abnormalities associated with rupture of the interventricular septum complicating myocardial infarction. | Left ventricular wall motion abnormalities, the extent and location of coronary artery stenoses, and the radiographic evidence of pulmonary venous hypertension were analyzed in a retrospective study of 40 patients who had surgically proven rupture of the interventricular septum after myocardial infarction. In 33 patien... | 102,143 | [
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Pitfalls of transhepatic portal venography and therapeutic coronary vein occlusion. | Coronary vein occlusions via transhepatic portography for bleeding esophageal varices was attempted in 24 patients. Problems occurred that either prevented the attempt or resulted in less than adequate occlusion. These included blood flow in the left gastric (coronary) vein toward the liver due to occluded or stenotic ... | 102,154 | [
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0.07177283,
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0.3959857,
0.3413426,
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Transcatheter gelfoam embolization of posttraumatic bleeding pseudoaneurysms. | Diagnostic angiography combined with transcatheter therapeutic embolization is a simple and effective means of treating complex clinical situations associated with posttraumatic hemorrhage. Bleeding pseudoaneurysms, even when large, can be readily managed by this combined modality with resultant decrease in morbidity a... | 102,155 | [
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Transcatheter embolization: prevention of embolic reflux using balloon catheters. | Reflux of embolic material during therapeutic transcatheter embolization is a potential complication which can result in occlusion of distal vascular beds. The conditions under which reflux was demonstrated in laboratory animals include (1) low flow states, (2) overvigorous flushing, (3) selective contrast injections, ... | 102,156 | [
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Bleeding simulated by the distal internal pudendal artery stain. | A capillary and venous phase blush in the region of the distal branches of the internal pudendal artery that simulates bleeding can sometimes be seen on arteriograms of male patients who are not bleeding. We describe five such cases. Correct identification of this pooling of contrast material is important to avoid unne... | 102,157 | [
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Increasing the predictive value positive of the precipitin test for the diagnosis of deep-seated candidiasis. | Three hundred fifty human sera were tested by double immunodiffusion, crossed-line electrophoresis, and crossed immuno-affinoelectrophoresis with a concanavalin A intermediate gel for precipitating antibodies to antigens present in cytoplasmic extracts of Candida albicans. Sera from 48 of 287 hospitalized patients at r... | 102,183 | [
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... |
Is the concept of "control group" valid? A quantitative comparison of behavior of caged baboon groups. | Behavioral comparisons between six caged baboon groups indicate that the groups have consistent and similar behavioral attributes. At the same time it is possible to distinguish between classes of animals in each group such as males versus females and high status versus low status rank. Comparable results are obtained ... | 102,209 | [
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Antimicrobial drug usage in general hospitals in Pennsylvania. | The Inter-Society Committee on Antimicrobial Drug Usage has conducted a survey of 20 randomly selected general hospitals in Pennsylvania. Records studied were of 5288 patients who either died or were discharged on 10 random days throughout 1974. About 28% of these patients received at least one antimicrobial drug durin... | 102,227 | [
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Endogenous endophthalmitis associated with bacillus cereus bacteremia in a cocaine addict. | A 22-year-old black female intravenous cocaine addict presented with an endophthalmitis of the right eye. Diagnostic evaluation included an immediate anterior chamber paracentesis and a delayed vitreous aspiration. Although cultures from the involved eye were negative, all 7 blood cultures grew Bacillus cereus suggesti... | 102,235 | [
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0... |
[Use of protein-free potato juice concentrates in the production of tetracycline]. | The study on the use of potato juice concentrate in tetracycline production showed that the tetracycline-producing strain 3-NK of Actinomyces aureofaciens grown on seed and fermentation media containing 2--2.5 and 0.35--0.45 per cent (by dry substance) of the concentrate produced the same antibiotic yield as that on th... | 102,242 | [
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... |
[Simple qualitative methods of detecting beta-lactamase-producing strains of microorganisms]. | Modifications of two microbiological qualitative methods for detection of beta-lactamase-producing microbial strains are described. The methods are based on the principle of Goths. One of the methods named "contact" significantly differs from the prototype and is more simple, convenient, easily reproducible and does no... | 102,243 | [
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[A simplified arteriographic analysis of systolic pressure and of the pressure-time index]. | Systolic stress has been measured in 20 ms periods during ventricular ejection by monoplanar angiographic method, both under basal conditions and after infusion of trinitro-glycerine (TNG) in 8 coronary patients. None of them showed significant segmental contraction abnormality. No correlation was found between the cor... | 102,271 | [
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0.1046501,... |
[Obstructive cardiomyopathy and associated coronary atherosclerosis. Review of the literature and report of 2 personal cases]. | The association of idiopathic hypertrophic subaortic stenosis (IHSS) with significant coronary atherosclerosis is little known, only 43 cases being available in the literature, 2 of which are personal ones. But the incidence of this association has certainly been underestimated. It is especially found from the sixth de... | 102,292 | [
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... |
Neurofibromatosis and pregnancy. | Ten patients with neurofibromatosis were studied in 27 pregnancies. Two of the patients had evidence of pre-eclampsia in their first pregnancy but not in subsequent ones. In all other pregnancies, no adverse features were noted. It would seem that neurofibromatosis is not specifically associated with any obstetric comp... | 102,334 | [
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A high-potential redox component located within cyanobacterial photosystem II. | The calcium-dependent oxygen evolution activity of preparations of Phormidium luridum shows a marked selectivity in favor of ferricyanide over benzoquinone as Hill oxidant. In addition, the rate of oxygen evolution increases with increasing solution redox potential over the range +350 to +550 mV vs. the standard hydrog... | 102,342 | [
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The luteinizing hormone-releasing hormone (LH-RH) neuronal networks of the guinea pig brain. I. Intra- and extra-hypothalamic projections. | In the guinea pig brain, LH-RH-containing cell bodies are located not only within the classical hypophysiotrophic area but also in the medial preoptic area, septum and olfactory tubercle. LH-RH fiber tracts project not only to the primary portal plexus in the median eminence but also throughout the limbic forebrain and... | 102,406 | [
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-... |
Expression of Ricinus communis receptors on epithelial cells in oral carcinomas and oral wounds. | The histological distribution of receptors for Ricinus communis Fraction 1 (RCA1) in oral carcinomas and in oral epithelial cells during wound healing has been studied by use of fluorescein-tagged RCA1. Biopsies from 15 human oral carcinomas and adjacent normal mucosa showed RCA1 receptors at the cell membranes in the ... | 102,424 | [
0.1925889,
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0.3475,
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0.158... |
Total synthesis of ceramide trihexoside accumulating with Fabry's disease. | We report the synthesis of natural ceramide trihexoside, viz. gal (alpha-1 leads to 4) gal (beta-1 leads to 4) gluc (beta-1 leads to 1) ceramide (XIII). It involves the Koenigs-Knorr reaction of the bromide II with the aglucon XIX, and of the chloride VII with the D-enantiomer of the ceramide ester XII. A positional is... | 102,432 | [
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[Plasma estradiol levels in quail during sexual development and after different estrogenic treatments]. | The comparison between estradiol levels in peripheral plasma of developing quails and of estradiol benzoate treated quails (0.01, 0.02, 0.1 and 1 mg/daily/6 days) shows that only the dose of 0.01 mg reproduces the conditions of a physiological estrogen stimulation. | 102,440 | [
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... |
[Adrenal gland growth of the ovine fetus in the end of gestation: evolution of DNA and of membrane proteins]. | The adrenal weight of the ovine fetus increases dramatically during late pregnancy. This increase is achieved in three periods: one of DNA duplication between two phases of cellular hypertrophy. During cellular hypertrophy an important biosynthesis of membrane proteins is observed. This development concerns essentially... | 102,441 | [
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[Speed of in vitro reassociation of gonadotropin subunits in a teleost fish, the carp (Cyprinus carpio L.)]. | Purified gonadotropin subunits of a teleost Fish, the Carp, reassociated in vitro, according to a second order rate reaction. The rate constant was temperature dependent. Compared to ovine LH, the Q10 was about three times less and the rate constant much greater (160 times for instance at 20 degrees C). The possible ph... | 102,442 | [
0.09230775,
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0.09069878,
-0.09943437,
-0.02636886,
-0.09289453,
0.1278881,
0.0962666,
-0.01473384,
0.2273026,
0.02315308,
0.2226686,
-0.1184089,
-0.3668585,
-0.3229121,
-0.4593787,
0.07336832,
0.1649771,
0.1400152,
0.510847,
-0.231463,
0.02146832,
... |
[Species specific esterase profiles in the genus Serratia]. | Esterases of 62 Serratia marcescens, S. liquefaciens, S. plymuthica and S. marinorubra strains were analysed by electrophoresis in polyacrylamide-agarose gel. The comparative distribution of bands showed that the four Serratia species were characterized by distinct electrophoretic patterns of their esterases. | 102,456 | [
-0.09721841,
0.05851755,
0.1978261,
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0.03271591,
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0.002289423,
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0.3166687,
0.4263755,
0.2099217,
0.3408236,
-0.003096911,
-0.0... |
Results with commercial radioassay kits compared with microbiological assay of folate in serum and whole-blood. | We compared results with three commercial folate radioassay kits [Bio-Rad, New England Nuclear (NEN), and RIA Products] with those by microbiological assay for more than 200 samples of human serum and whole blood. All but one kit (NEN) compared favorably with the microbiological assay for serum samples, although there ... | 102,464 | [
-0.1400192,
0.02183354,
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0.2707686,
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0.16764,
0.4378964,
0.2202632,
0.5569925,
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0.2498749,
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0.3241989,
0.2678132,
0.5593714,
-0.02362423,
... |
Autoradiographic localization of the uptake of 3H-beta-alanine in rat nervous tissue cultures. | Autoradiographic studies on the uptake of 3H-beta-alanine have shown that, in spinal cord and brain stem cultures, both neurones and glial cells have accumulated the amino acid. In contrast, in cultures of cerebellum and dorsal root ganglia, 3H-beta-alanine was only t aken up by glial elements. | 102,522 | [
0.1082173,
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0.126351,
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0.2027683,
0.3138188,
0.2035593,
0.2401349,
-0.... |
Karyotype abnormalities in two primate species, Pygathrix nemaeus and Lemur coronatus. | The karyotypes of 7 douc langurs (Pygathrix nemaeus) and 3 crowned lemurs (Lemur coronatus) were examined. Abnormalities in 23.5% of the karyotypes of 1 male douc langur were associated with a history of fathering stillborns and abortuses (38%). Karyotype analysis of an apparently normal female lemur revealed three dif... | 102,569 | [
0.1478532,
0.414403,
0.02911595,
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0.451877,
0.1537291,
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-0.142... |
Changes through the day in the food choice of wild gibbons. | Several studies of primates have found that they tend to eat different foods at different times of day. A detailed study of a small sample of siamang and lar gibbons shows that they select figs in the morning, young leaves in the afternoon and figs again for the last feed of the day. Various explanations of these choic... | 102,571 | [
0.10695,
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0.06831865,
0.3934094,
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Criteria for internal auditing. | An effective, inclusive internal auditing endeavor should help assure hospital managements that (1) an adequate system of internal control exists to assure the safeguarding of assets and the reliability of data produced by the financial information system, (2) uneconomic operating practices are detected promptly so the... | 102,583 | [
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0.01239604,
-0.06827071,
0.124297,... |
Ultrastructure of tissue in intrabony and subperiosteal porous ceramic implants. | Porous ceramic (Al2O3) implants with pore size of 100--750 micron were placed intrabony in the maxilla and subperiosteally in the mandible of three adult monkeys. After observation periods of 10, 11 and 12 months, the animals were perfused with 1.7% glutaraldehyde and the jaws processed for electron microscopy. Tissue ... | 102,603 | [
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0.03253188,
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0.139405,
0.... |
Disphosphonate dynamic imaging of experimental bone grafts and soft tissue injury. Radionuclide bone imaging. | Bone imaging provides two significant advantages over previously available methods for assessing bone processes. First, as scanning is non-invasive, it offers the operator the ability to sequentially follow any area of bone without altering it as would a biopsy. The second advantage is the ability of bone imaging to pr... | 102,606 | [
-0.5602899,
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0.02767265,
0.1854305,
0.2663663,
0.1381241,
-0.087... |
Clavulanic acid inhibition of beta-lactamase I from Bacillus cereus 569/H. | Inactivation of beta-lactamase I by clavulanic acid was investigated. Clavulanic acid induced inhibition of the enzyme was found to be progressive with time. Benzylpenicillin provided protection against the adverse effects of the inhibitor initially, however, the enzyme was irreversibly inhibited in a progressive manne... | 102,630 | [
-0.2240639,
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0.2295831,
0.7314708,
0.1644836,
0.2279275,
... |
Tibial fractures involving the ankle in children. The so-called triplane epiphyseal fracture. | Triplane fractures of the distal end of the tibia in fifteen children (average age, thirteen years) represented 6 per cent of 237 consecutive epiphyseal fractures of the ankle. Thirteen children were treated by closed methods (including manipulation) and two had open reduction of the fractures. At an average of twenty-... | 102,648 | [
-0.3711573,
0.4004704,
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0.004042154,
0.1525829,
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0.2450099,
0.1091951,
0.04768625,
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0.3022876,
-0.1135717,
-0.03074836,... |
Comparison of sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. | A study was conducted to compare the sensitivity and specificity of purified lymphocyte and whole-blood in vitro lymphocyte stimulation assays in detection of Brucella abortus infection in cattle. Cattle used were infected with B. abortus field strains or strain 19. Peripheral blood was collected, and lymphocytes for t... | 102,656 | [
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0.1430499,
0.5081249,
-0.02924435,
-0.050... |
Determination of immunoglobulin A concentrations in human nasal secretions with a serum immunoglobulin A standard. | By quantitative immunodiffusion tests, nasal secretion immunoglobulin A was underestimated by approximately 5.6-fold when the serum 7S immunoglobulin A standard was employed. | 102,657 | [
-0.3508492,
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0.197227,
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... |
The identification of relay neurons in the dorsal lateral geniculate nucleus of monkeys using horseradish peroxidase. | Intraaxonal retrograde transport of the protein horseradish peroxidase (HRP) was used to identify relay neurons in the dorsal lateral geniculate nucleus (LGN) of owl (Aotus trivirgatus) and rhesus (Macaca mulatta) monkeys. In both species, from 94.1-98.6% of the neurons within columns extending through both parvocellul... | 102,664 | [
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0.08433658,
0.08391155,
0.2434344,
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... |
An attempt at immunotherapy of murine virus erythroleukemia. | It was demonstrated that the nonvirulent strain of Listeria monocytogenes isolated from vegetable matter prolonged significantly the survival time of mice inoculated with murine virus erythroleukemia. The most significant survival time was recorded when live listeriae were administered on the same day but into another ... | 102,689 | [
-0.09311808,
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0.2014326,
0.3075626,
0.3912013,
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... |
Xenogenic response of human peripheral blood lymphocytes against murine cells in vitro. | Human peripheral blood lymphocytes (HPBL) were sensitized to mitomycin-treated murine spleen cells and mitomycin-treated mastocytoma P-815. A DNA proliferative response occurred to both cell types. The sensitized HPBL lysed chromium-51-labelled mastocytoma P-815 cells in a cell-mediated cytotoxicity assay (CMC). Eviden... | 102,702 | [
-0.1587421,
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0.318612,
0.4351099,
0.2548556,
0.1075193,
-0.0... |
Antigen-specific suppressor T-cell activity in genetically restricted immune spleen cells. | Virgin spleen cells develop comparable primary antibody responses in vitro to syngeneic or allogeneic macrophages (Mphi) bearing the terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT), whereas immune spleen cells primed with syngeneic or allogeneic GAT-Mphi develop secondary responses preferentially when stimu... | 102,722 | [
0.1651705,
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0.5761427,
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0.009481081,
0.216967,
-0... |
The role of calcium ions in the synthesis and transport of noradrenaline carrier vesicles in guinea-pig sympathetic neurons in vitro. | Guinea-pig inferior mesenteric ganglia (IMG)/hypogastric nerve preparations were incubated in tissue culture media containing ethylene glycol-bis-(beta-aminoethyl ether)N,N'tetra-acetic acid (EGTA) or colchicine and examined either by fluorescence microscopy or by transmission electron microscopy. Two millimolar EGTA i... | 102,736 | [
-0.1010155,
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0.03596571,
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0.3717648,
0.4333511,
0.2853597,
0.3228068... |
Hemangioma calcificans. Case report of an intraparenchymatous calcified vascular hematoma with epileptogenic potential. | A middle-aged woman, with a previous history of medically suppressed absence attacks, presented with mild changes in mental status and a skull film demonstrating several areas of mottled, granular, intracranial calcifications. These lesions, although readily visible on computerized tomography, appeared avascular during... | 102,737 | [
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0.1154646,
0.1312622,
-0.05934235,
0.3... |
Does the supplementary motor area play a part in modifying motor cortex reflexes? | Neuronal activity in the supplementary motor area was recorded from a monkey performing a trained motor task that required readiness for proper usage of sensory inputs. Thirty-two neurons exhibited activity changes, which supports the hypothesis that the SMA is part of the system involved in modulating responsiveness o... | 102,779 | [
-0.1258003,
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0.157699,
-0.09698755,
0.2027478,
... |
Ultrastruct of red-sore lesions on largemouth bass (Micropterus salmoides): associattion of the ciliate Epistylis sp. and the bacterium Aeromonas hydrophila. | Epizootic outbreaks of red-sore disease in several reservoirs in the southeastern United States have been reported to cause heavy mortality among several species of fish having sport and commercial value. The etiologic agent is said to be the peritrich ciliate Epistylis sp.; secondary infection by the gram-negative bac... | 102,785 | [
-0.2779387,
-0.0694921,
-0.09065197,
0.2472296,
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-0.4357336,
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0.03754707,
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-0.07159194,
0.2152726,
-0.3011061,
0.1033134,
0.1644045,
-0.2728018,... |
The effect of glucose on the biochemical and ultrastructural characteristics of developing Euglena chloroplasts. | Chloroplast development is inhibited in Euglena gracilis strain Z, when greened in a medium containing glucose. This inhibition is reflected not only in the pattern of chlorophyll accumulation but also in the chloroplast ultrastructure and activities of the 2 light reactions of photosynthesis. Chloroplasts of cells gre... | 102,787 | [
0.2425249,
0.1436464,
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0.04701276,
0.2083331,
0.006877855,
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0.1666079,
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0.2665814,
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0.2900784,
0.6980194,
0.3850887,
-0.09765173,
... |
Synthesis and carcinogenic activity of 5-fluoro-7-(oxygenated methyl)-12-methylvenz[a]anthracenes. | Treatment of 7,12-benz[a]anthraquinone (2) with methylmagnesium iodide or methyllithium yields mixtures of cis- and trans-7,12-dihydro-7,12-dihydroxy-7,12-dimethylbenz[a]anthracenes (3a,b), in which the ratio of cis to trans lies in the 3--4:1 region. Each isomer afforded high yields of 7-chloromethyl-12-methylbenz[a]a... | 102,793 | [
-0.6832026,
0.1140255,
-0.3508101,
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0.001894931,
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0.1321463,
0.7043743,
0.1460775,
-0.1610887,
... |
Inhibition by potassium ion of the pregerminative response to L-alanine of unactivated spores of Bacillus cereus T. | The effect of potassium ion on L-alanine-inosine-induced germination of unactivated spores of Bacillus cereus T was studied. Unactivated spores germinated in 0.1 M sodium phosphate buffer (NaPB), but not 0.1 M potassium phosphate buffer (KPB), at pH 8.0 and at 30 C. Inhibition of germination was also observed on incuba... | 102,904 | [
-0.2007474,
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-0.1811037,
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0.01295033,
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0.4113961,
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0.3361337,
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0.1171472,
-0.3104202,
-0.05565106,
0.8019615,
0.1575563,
0.162287,... |
[The persistence of pathogens and its immunepathological consequences]. | In principle the persistence of pathogens is favored by disturbances of the interplay between specific humoral and cellular defence mechanisms in the particular individual characteristic. Clinical secondary reactions in persistence of infection are in many cases not characterized by the infection as such but more decis... | 102,991 | [
-0.1244945,
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0.0766118,
0.004001171,
0.02478531,
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0.4149647,
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0.05241081,
0.171784,
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0.05573175,
0.2819895,
0.1368032,
0.08322003,
-0.1100469,
... |
Rearrangement of genetic information may produce immunoglobulin diversity. | The nearly complete amino-acid sequences of 22 closely related immunoglobulin kappa variable (Vkappa) regions from the inbred NZB mouse are presented. This group of Vkappa regions is encoded by at least six germline Vkappa genes. These data also suggest that the mouse kappa gene is divided into three segments termed V ... | 103,003 | [
0.07514442,
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0.329922,
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0.2346675,
0.244054,
0.3898476,
0.02342525,
-0.2125556,
0.1... |
Persistent bacteriuria in the rat after reflux challenge with Pseudomonas aeruginosa. | An experiment based upon reflux of culture suspensions of Pseudomonas aeruginosa into the rat kidney was set up to examine possible factors of importance in the development of ascending renal infection. We monitored the persistence of challenge bacteria in the rat urinary tract by quantitative culture of urine collecte... | 103,062 | [
0.05964042,
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0.2371426,
0.2343802,
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0.2146543,
0.2819087,
0.001106295,
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0.198719,
0.1487903,
0.1830481,
... |
[Serum aminoacid levels during aminoacid-free parenteral feeding (author's transl)]. | 19 patients in a surgical intensive care unit were fed parenterally on an aminoacid-free diet and the serum aminoacid levels were determined chromatographically on ion exchange resins. The results were compared with those obtained in 150 normal persons. The significance of the findings is discussed. | 103,084 | [
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0.1041106,
0.320936,
-0.1210321,
0.05336719,
... |
Introduction of antigenic phospholipids into the plasma membrane of mammalian cells: organization and antibody-induced lipid redistribution. | Phosphatidylethanolamine bearing the 2,4,6-trinitrophenyl hapten was introduced into the surface membrane of mammalian fibroblasts by incubating the cells with small unilamellar vesicles containing this hapten-conjugated lipid. Consistent with integration of the antigen into the plasma membrane lipid bilayer, the exoge... | 103,095 | [
-0.172685,
-0.03483551,
-0.2624328,
-0.08755825,
0.2903378,
-0.1350802,
0.04815446,
0.4014216,
0.08008045,
0.3016203,
0.1321436,
-0.05503837,
0.01791378,
-0.06098793,
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-0.3929125,
0.1363769,
0.0306109,
0.2654608,
0.1887296,
0.2434898,
-0.1987545,
... |
Interaction between d-amphetamine and ethanol with respect to locomotion, stereotypies, ethanol sleeping time, and the kinetics of drug elimination. | The interaction between d-amphetamine and ethanol with respect to locomotor activity, stereotyped behavior, and sleeping time was investigated in rats. Ethanol 0.8 g/kg i.p. enhanced and prolonged locomotor activity produced by d-amphetamine 1 mg/kg s.c. The increased motility after 5 mg/kg d-amphetamine was not influe... | 103,115 | [
-0.2637302,
0.09527871,
-0.3970741,
0.1606474,
0.1843749,
-0.1958869,
-0.1551326,
-0.3746704,
-0.1555193,
-0.1136777,
0.1619227,
-0.3210868,
-0.07917915,
0.3842107,
-0.3277104,
-0.03744404,
-0.6636148,
0.001586682,
-0.2844064,
0.1766649,
0.1689021,
-0.01621863,
0.1632421,... |
Neurologic computed tomography in a defined population group. | A total of 766 residents of Olmsted County, Minnesota, underwent neurologic computed tomography (CT) from June 1973 through 1976; 981 scans were performed. The number of CT scans per 1,000 population increased each year and, during the period studied, the average rate based on the initial scan in each case was 2.4 and ... | 103,134 | [
-0.138013,
-0.005576485,
0.04636945,
-0.2324131,
-0.08352531,
-0.1412113,
-0.3441446,
-0.08226214,
-0.04156668,
-0.04826286,
-0.1752144,
-0.09185132,
0.2244034,
0.24787,
-0.2525023,
-0.07230108,
-0.2641655,
0.3579037,
0.2897885,
-0.02956036,
0.02488888,
0.3665516,
-0.0287... |
Synthesis of immunoglobulin by normal and antigenically stimulated fetal sheep. | The rate of appearance, quantity and immunochemical character of serum immunoglobulins which appear normally during the development of fetal sheep and following the injection of antigens at different stages of gestation have been studied. After 70 days' gestation a percentage of normal fetal sheep synthesise IgM. Altho... | 103,153 | [
-0.1272352,
-0.1132369,
-0.331177,
-0.1228687,
0.7036817,
-0.06931894,
-0.2144154,
-0.02404478,
-0.2233988,
0.30294,
0.1333376,
0.04517084,
-0.03709729,
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-0.0176498,
0.1720636,
-0.2165076,
0.197021,
0.4319314,
0.113603,
-0.05904385,
-... |
Myelomatosis after phenytoin therapy: a chance association? | The occurrence of a monoclonal gammopathy followed by IgG-lambda multiple myeloma is described in a patient receiving diphenylhydantoin therapy for 20 years for epilepsy. Despite the known association between the drug and the development of immunosuppression and lymphoma, we regard the association recorded in this case... | 103,187 | [
-0.07434445,
-0.07638849,
0.08760305,
-0.06887767,
0.2421192,
-0.4083463,
-0.3689374,
0.06518821,
-0.1865957,
0.2982556,
0.1775687,
0.5261768,
0.1901262,
0.1313484,
-0.2071954,
-0.01448344,
-0.03056891,
0.2924952,
0.1669924,
-0.1066616,
0.05045385,
0.03047972,
-0.1506116,... |
Gold serum levels in children with juvenile rheumatoid arthritis. | Serum gold levels were monitored in 66 children with juvenile rheumatoid arthritis, treated with different i.m. dosage schedules of sodium aurothiomalate (Myocrisin, Pharma Rhodia). The ages of the children varied from 1 to 15 years. Gold serum levels in children were related to the dose of Myocrisin calculated per kg ... | 103,189 | [
-0.1509293,
-0.2253588,
-0.5482124,
-0.120121,
-0.009808883,
0.03390781,
-0.4418792,
0.0138532,
0.03342249,
-0.07926084,
0.07204735,
0.1943778,
0.2693925,
0.08235421,
-0.3008844,
0.3033283,
0.01425572,
-0.1812494,
-0.01066143,
0.05435804,
0.06455574,
-0.2429912,
-0.067971... |
Comparison of penicillamine and gold treatment in early rheumatoid arthritis. | In a series of 100 adult patients with definite rheumatoid arthritis of at most 3 years' duration and with no previous penicillamine, gold or systemic corticosteroid treatment, 50 patients were treated with D-penicillamine and 50 with gold for one yar. The dose of penicillamine was 600 mg daily. Sodium aurothiomalate w... | 103,190 | [
0.1700625,
-0.305176,
-0.2443231,
0.02991457,
0.09191908,
-0.3400006,
0.0632412,
0.001565524,
-0.1687545,
-0.01623565,
0.1062017,
0.169359,
0.235409,
-0.08306301,
-0.3297997,
0.2607679,
-0.1537173,
0.2000399,
-0.03622213,
-0.1146716,
-0.09510628,
-0.05998411,
-0.05559392,... |
Calcium entry leads to inactivation of calcium channel in Paramecium. | Under depolarizing voltage clamp of Paramecium an inward calcium current developed and subsequently relaxed within 10 milliseconds. The relaxation was substantially slowed when most of the extracellular calcium was replaced by either strontium or barium. Evidence is presented that the relaxation is not accounted for by... | 103,199 | [
-0.1071375,
-0.07884935,
-0.4842479,
-0.1974272,
-0.03357277,
-0.2280734,
0.1859917,
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0.1812887,
0.01000232,
0.05708767,
0.4407988,
-0.1018747,
0.0739713,
-0.2326647,
-0.05281014,
-0.5353497,
-0.02316362,
-0.3696893,
-0.127836,
0.5224296,
0.1759345,
0.3265509,... |
The Montgomery lecture, 1977. Curious colobomata. | The humble coloboma has been taken as a model in an attempt to illustrate the benefit of continued observation and the application of increasingly sophisticated methods of investigation in the genetic and biochemical areas. The recent literature is reviewed with particular reference to publications dealing with colobom... | 103,250 | [
0.04962935,
-0.4213621,
-0.4171966,
-0.236449,
0.08991978,
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-0.1738102,
0.04368303,
0.1653633,
-0.0726875,
0.1811811,
0.3351245,
0.1778242,
-0.2035783,
-0.1750087,
0.2952884,
-0.3112866,
-0.2226416,
0.2369265,
0.1318375,
0.464597,
0.1630951,
-0.1235045,
0.021... |
Integrated therapy for invasive bladder carcinoma. Experience with 108 patients. | One hundred eight patients with invasive bladder carcinoma, clinically staged T3, who underwent preoperative irradiation followed by radical cystectomy and ileal conduit urinary diversion without pelvic lymphadenectomy at this Center between January 1, 1969, and December 30, 1975, were reviewed. Sixty-two patients are ... | 103,270 | [
-0.1218437,
-0.04931724,
-0.2700367,
-0.3131482,
0.05994598,
-0.5476803,
0.3122522,
-0.1725123,
0.001392424,
0.2233006,
0.07367634,
0.1282819,
-0.2579826,
-0.3853779,
-0.4188634,
-0.2439051,
-0.2840352,
0.06291668,
-0.1349227,
-0.00002236342,
0.3527472,
0.5484784,
0.01207... |
[Microbial contamination of dust in minimum-morbidity housings for pig rearing]. | The range of the microbial contamination of 1 g of dust in minimum-morbidity pig rearing houses is from 2.9 . 10(7) to 7.6 . 10(9) in the microbes growing on meat-peptone agar (MPA), from 4.6 . 10(7) to 4.6 . 10(8) in moulds growing on the Czapek-Dox agar, from 1.4 . 10(2) to 7.0 . 10(4) in the total number of microbes... | 103,275 | [
0.05942348,
-0.0523285,
0.6240214,
0.1034959,
-0.31175,
-0.1279878,
-0.1235878,
0.3640617,
0.2023118,
-0.4952664,
-0.01261143,
-0.2721257,
0.4155019,
0.2874431,
-0.5597332,
0.1335541,
-0.7115684,
0.02672158,
0.6524552,
-0.008015713,
0.2083826,
0.3721313,
0.1006832,
-0.2... |
[Diagnosis of infectious anemia in horses using the Coggins test]. | Coggins' immune diffusion test was modified, and was applied as a screening one in the study of the epizootic status. The positive reactions were characterized by the production of a precipitation line between the antigen and the respective serum that was tested. The appearance of such a line was associated with that f... | 103,281 | [
-0.09370513,
-0.1257396,
0.03600188,
0.04367431,
0.1403933,
-0.0762644,
-0.04016059,
0.100176,
-0.2100526,
-0.1535118,
0.105612,
0.2993934,
0.1883003,
0.1880054,
-0.4477225,
-0.3067337,
-0.3746133,
-0.1381893,
-0.07135305,
0.1813475,
0.1737246,
-0.1179309,
-0.1921728,
0... |
Tumors as clonal proliferation. | Cytogenetic studies indicate that most tumors are clonal (i.e. unicellular in origin) and have karyotypic alterations. These are not consistent, but non-random abnormalities are being increasingly identified by banding techniques, pointing to the sites on human chromosomes where genes important in neoplastic developmen... | 103,306 | [
-0.1776235,
-0.06626003,
-0.06445818,
-0.2407912,
0.1181921,
-0.2301014,
-0.2408139,
0.008458006,
0.1527527,
0.1546855,
-0.007455599,
-0.01004318,
-0.1914598,
0.4643295,
-0.4087351,
-0.2815115,
0.1673049,
0.02464618,
0.2759374,
-0.0390906,
0.3401738,
0.03293746,
-0.137554... |
Some comments regarding chromosome pulverization (premature chromosome condensation or PCC, prophasing). | Premature chromosome pulverization (PCC) or prophasing is a much misunderstood cytological entity. It must be separated from chromosome damage caused by a number of chemical, physical and biological agents. Prophasing is observed in fused cells in which one of the constituent cells must be in metaphase and another in i... | 103,307 | [
-0.2654219,
0.09798776,
0.07010407,
0.03584056,
0.1668604,
-0.03228426,
-0.4720925,
0.1086524,
0.3521379,
0.2156301,
0.08408764,
-0.1256102,
-0.2312475,
0.1082633,
-0.2873082,
-0.05009934,
-0.2322334,
-0.07632302,
0.2735138,
-0.0978982,
0.3032059,
0.2776431,
-0.1396409,
... |
Clinical implications of chromosome abnormalities in acute non-lymphocytic leukemia: current status. | Data currently available on banded chromosome studies on patients with ANLL suggest that the presence of a chromosome abnormality in such patients indicates a poor prognosis, and that different treatment strategies need to be developed for these patients. However, patients with at least one normal metaphase survive nea... | 103,314 | [
-0.2434918,
-0.04884419,
0.0006772607,
-0.3311508,
-0.2164396,
-0.05503241,
0.03597448,
0.05056011,
0.007696202,
0.139044,
0.09255154,
0.04450692,
0.008954977,
0.181193,
-0.5645137,
-0.3916988,
-0.3273465,
0.02698993,
-0.2053971,
0.1404492,
0.4830467,
0.1967329,
-0.289711... |
Blood group phenotypes and the origin of sickle cell hemoglobin in Sicilians. | As an approach to investigating the origin of sickle cell hemoglobin (hemoglobin S) in white persons of Sicilian ancestry, two groups of native Sicilians were tested for blood group evidence of African admixture. Among 100 unrelated Sicilians, the phenotypes cDe(Rho) and Fy(a-b-), and the antigens V(hrv) and Jsa, which... | 103,355 | [
-0.0742787,
-0.2804989,
0.2454312,
-0.220759,
-0.1045105,
-0.3643813,
-0.1618192,
0.2663504,
0.1418752,
0.3063675,
0.07533088,
0.1770847,
-0.1843527,
-0.2794234,
-0.3660973,
-0.5108351,
0.09861962,
-0.2039129,
0.7439331,
0.08068642,
0.251334,
0.3488907,
-0.5942078,
0.07... |
Computed tomography in adrenal tumors. | Computed tomography (CT) was used to evaluate 26 patients with a variety of adrenal lesions. Surgical proof was available in 22 patients and clinical confirmation with a variety of other studies in the other four patients. Nine patients ahd aldosterone-producing adrenal adenomas and CT correctly identified seven. Four ... | 103,401 | [
-0.3486067,
0.2663766,
-0.3591882,
-0.4814588,
0.08507097,
-0.2359335,
-0.514774,
0.1629438,
0.1959499,
-0.05711976,
0.1857944,
0.07299411,
-0.08977414,
-0.2634268,
-0.3988717,
-0.1241993,
0.1030069,
0.3969105,
0.1968812,
0.1876196,
0.194467,
0.210844,
-0.2057715,
0.147... |
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