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Mutans Streptococci Colonization in Relation to Feeding Practices, Age and the Number of Teeth in 6 to 30-Month-Old Children: An in vivo Study.
Early childhood caries has been characterized as first affecting the primary maxillary anterior teeth, followed by the involvement of the primary molars. Other terms for dental caries in preschool children, which inappropriately may imply cause for the disease, includes baby bottle tooth decay, nursing caries, milk bot...
25,206,151
[ 0.03738607, 0.1973665, -0.08240063, 0.06864807, -0.2089462, -0.2432332, -0.2139631, 0.05112397, -0.08024567, -0.208405, 0.2738852, -0.06453869, -0.05969175, 0.07949085, 0.04053589, -0.1005516, -0.193445, 0.2161834, -0.1121306, -0.1893366, 0.4807229, 0.08639775, -0.0029213...
Is there an Association between Oral Health Status and School Performance? A Preliminary Study.
The present cross-sectional study was carried out to assess the impact of poor oral health status on school performance of 600 primary and nursery school children of Bengaluru city, India. The data were collected using the methods and standards recommended by the WHO for oral health surveys. Oral health status was asse...
25,206,152
[ -0.2509881, 0.1846988, 0.1869703, 0.01708907, 0.05701632, -0.2793971, -0.1735724, 0.007875656, -0.05442258, -0.1391807, 0.3800207, 0.3190767, -0.1075545, -0.04873985, -0.666845, -0.5700901, 0.1828652, 0.005844699, -0.3203034, -0.006810987, 0.02887727, 0.1525136, 0.1167167...
Customization of stock eye prosthesis for a pediatric patient by a simplified technique.
The unfortunate loss or absence of an eye may be caused by congenital defect , irreparable trauma, tumor or blind eye. The role of the maxillofacial prosthodontist in fabricating an ocular prosthesis to restore facial symmetry and normal appearance for the anophthalmic patient becomes essential. A custom-made ocular pr...
25,206,159
[ -0.3578949, -0.02245449, -0.4597313, 0.02366341, 0.0837433, -0.2051266, -0.353028, 0.1261595, 0.3178266, 0.0842616, 0.4033949, 0.1497027, -0.3530053, 0.0323714, -0.3032093, -0.2439677, -0.1818787, -0.425674, -0.2783563, -0.1045261, -0.14494, 0.03751921, -0.1470662, 0.19...
Glassfiber post: an alternative for restoring grossly decayed primary incisors.
Restoration of primary incisors, which have been severely damaged by rampant caries or trauma, is a difficult task for the pediatric dentist. With the introduction of new adhesive systems and restorative materials, alternative approaches for treating these teeth have been proposed. This paper discusses the restoration ...
25,206,160
[ -0.06150635, 0.5843731, -0.2397521, -0.04976705, 0.1361545, -0.09133135, -0.03347213, 0.1324175, 0.2997636, 0.4148592, 0.2550472, 0.5221764, -0.129871, -0.1964741, -0.1984002, -0.2821575, -0.2693745, -0.1355344, -0.2511996, -0.4215433, 0.2540395, 0.07139082, -0.1179996, ...
Management of Traumatic Injury to Maxillary Central Incisors associated with Inverted Mesiodens: A Case Report.
Maxillary incisors are the most frequently injured teeth in the primary and permanent dentition. Stage of adolescence show a significant number of dental injuries as they engage in contact sports. Children with accident prone profile, i.e. class II division I or class I type II malocclusion are more prone for injuries ...
25,206,184
[ -0.5107953, 0.482713, -0.02639529, -0.1192741, 0.1296265, -0.3032597, -0.8061406, -0.04640516, 0.184897, 0.2752649, 0.042062, 0.03082734, -0.4947492, -0.09023353, -0.124046, -0.7366002, -0.02519577, -0.1600723, -0.484525, -0.08200529, -0.240351, -0.111653, -0.01836947, ...
To Evaluate the Effect of Different Adhesive Materials on the Microleakage of Bonded Amalgam Restorations: An in vitro Study.
This study evaluated the ability of different adhesive materials in reducing the microleakage in class V amalgam restorations. Standardized class V cavities were prepared on the facial surface of 56 noncarious human premolars, they were then randomly divided into control and experimental groups based on adhesives used....
25,206,200
[ -0.2429964, 0.5927394, -0.1396247, -0.2216367, 0.09408559, -0.0381209, -0.2024371, 0.1664573, 0.1624808, -0.1059332, 0.1465032, -0.162273, 0.2887081, 0.0495075, 0.00243076, -0.1564025, -0.002782357, 0.1730575, -0.3772399, 0.1976674, 0.3152483, 0.175584, 0.1808994, 0.054...
Unusual presentation of an intraosseous hemangioma of the maxilla and displaced canine.
Intraosseous hemangiomas are benign vascular malformations which are extremely rare in the maxilla, but have been reported in the mandible, zygoma and orbital region. A 12 years old female presented to the oral and maxillofacial department with an ectopically positioned upper left canine in her zygomatic bone and bucca...
25,206,206
[ -0.4813927, 0.01941998, -0.1742406, -0.2673295, 0.06024496, -0.2045258, -0.1882186, -0.1649873, -0.09273639, 0.02164503, 0.2316826, 0.0557773, -0.4668078, -0.5101143, -0.5585198, -0.02845017, -0.3259763, 0.2165572, 0.03444139, -0.6239711, 0.001192114, 0.2448906, 0.0832312...
Riding pontic: a tool to keep patients smiling.
All patients expect a beautiful smile at the completion of orthodontic treatment, but some patients show concern regarding their appearance while undergoing treatment. The appearance of a gap from a missing tooth can be a concern, especially if it is in the display zone of a patient's smile. If the treatment plan inclu...
25,206,207
[ -0.2938614, 0.4960749, -0.006692994, -0.1188523, -0.06387921, -0.2338347, -0.1544698, -0.152422, 0.1483492, -0.2481766, 0.2462371, 0.04942769, -0.08064335, 0.122925, -0.3251788, 0.0323355, -0.2924088, -0.015451, -0.513347, -0.3202266, -0.04687896, 0.06720399, 0.204178, ...
Assessment of skeletal age in children with unilateral cleft lip and palate.
The objective of the study was to assess the skeletal maturity in children with unilateral cleft lip and palate (UCLP) and to compare it with that of the noncleft children. It is an institution based study conducted on randomly selected subjects visiting the hospital for consultation and treatment. A total of 60 childr...
25,206,213
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Parental Attitudes and Tooth Brushing Habits in Preschool Children in Mangalore, Karnataka: A Cross-sectional Study.
Adoption of consistent behavioral habits in childhood takes place at home, with the parents especially the mother, being the primary model for behavior. Tooth brushing habits which is learnt during early years of life, is deeply ingrained in the child's mind and it is expected that this leads to an adaptation of good o...
25,206,214
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Bilateral mandibular paramolars.
Supernumerary tooth is a developmental anomaly and has been argued to arise from multiple etiologies. These teeth may remain embedded in the alveolar bone or can erupt into the oral cavity. They can cause a variety of complications in the develo-ping dentition. Supernumerary teeth can present in various forms and in an...
25,206,236
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Small bowel adenocarcinoma and Crohn's disease: any further ahead than 50 years ago?
This review of the literature on small bowel carcinoma associated with Crohn's disease specifically addresses the incidence, risk factors, and protective factors which have been identified. It also reviews the clinical presentation, the current modalities of diagnosis, the pathology, treatment, and surveillance. Finall...
25,206,256
[ -0.0943738, -0.4404441, 0.005359177, -0.2935871, -0.2341921, -0.1074712, -0.09164053, -0.1339964, -0.04718917, -0.08617043, 0.1067133, 0.03358324, 0.2516898, -0.1096128, -0.1753574, -0.1910642, -0.3540927, 0.05576061, 0.307192, 0.008011527, 0.008948974, 0.1454618, -0.2234...
Chronic hepatitis B in 2014: great therapeutic progress, large diagnostic deficit.
This review analyzes progress and limitations of diagnosis, screening, and therapy of patients with chronic hepatitis B infection. A literature review was carried out by framing the study questions. Vaccination in early childhood has been introduced in most countries and reduces the infection rate. Treatment of chronic...
25,206,267
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Management of antiviral drug resistance in chronic hepatitis B.
Rescue antiviral treatment for patients with resistance to preexisting nucleos(t)ide analogues remains a clinical challenge. The correct choice of a first-line treatment of high potency and with a high genetic barrier to achieve sustained long-term suppression of viral replication provides the best chance of preventing...
25,206,270
[ -0.07524692, 0.1135791, 0.06505428, -0.2618175, 0.1037042, -0.2456523, -0.09569802, -0.0704148, 0.07795356, -0.06171929, 0.01227642, 0.0133228, -0.01388294, 0.3770925, -0.5456468, -0.4058365, -0.04212216, 0.02742143, -0.05837777, 0.2409301, 0.1236336, -0.03875781, -0.1628...
Clinical presentations of gastric small gastrointestinal stromal tumors mimics functional dyspepsia symptoms.
To explore whether clinical presentations of gastric small gastrointestinal tumors (GISTs) mimics gastrointestinal dyspepsia symptoms. The endosonographic data of 167 patients who underwent endoscopic submucosal dissection at the Tianjin Medical University General Hospital, China between 2009 and 2011 were analyzed. GI...
25,206,285
[ -0.2034736, 0.3750503, -0.1960827, -0.1431099, -0.2080797, -0.2179066, 0.07607815, -0.07270143, 0.1570416, 0.07506771, 0.2451713, -0.04981865, -0.2344078, -0.2842199, -0.1876201, -0.01232468, -0.4316373, 0.007190044, 0.398678, -0.1261213, -0.1029836, 0.4286398, -0.2376886...
Analytical strategies for discovery and replication of genetic effects in pharmacogenomic studies.
In the past decade, the pharmaceutical industry and biomedical research sector have devoted considerable resources to pharmacogenomics (PGx) with the hope that understanding genetic variation in patients would deliver on the promise of personalized medicine. With the advent of new technologies and the improved collecti...
25,206,308
[ 0.008970395, 0.02241197, 0.01515922, -0.1546142, -0.08537284, -0.2532949, -0.113906, 0.2747481, 0.1899946, 0.05543672, -0.2155891, -0.05545811, 0.01059336, -0.2089432, -0.5203911, 0.09240775, -0.02635737, 0.0874648, 0.06492644, 0.2633019, -0.07579318, 0.1856954, -0.256083...
Dielectric properties of porous silicon for use as a substrate for the on-chip integration of millimeter-wave devices in the frequency range 140 to 210 GHz.
In this work, the dielectric properties of porous Si for its use as a local substrate material for the integration on the Si wafer of millimeter-wave devices were investigated in the frequency range 140 to 210 GHz. Broadband electrical characterization of coplanar waveguide transmission lines (CPW TLines), formed on th...
25,206,316
[ 0.05974535, 0.000419905, 0.2349958, -0.195986, -0.1347915, -0.1329928, -0.1757754, -0.001822401, 0.1961468, 0.1248627, -0.0080049, -0.1208667, 0.05931274, -0.07960199, -0.7521038, -0.2939107, -0.5512321, -0.08304963, -0.09516152, 0.00519263, 0.1209459, 0.06729696, -0.0451...
Resolution of interaural time differences in the avian sound localization circuit-a modeling study.
Interaural time differences (ITDs) are a main cue for sound localization and sound segregation. A dominant model to study ITD detection is the sound localization circuitry in the avian auditory brainstem. Neurons in nucleus laminaris (NL) receive auditory information from both ears via the avian cochlear nucleus magnoc...
25,206,329
[ -0.08307914, -0.2116608, -0.2731703, -0.1714922, 0.1926892, -0.5074971, -0.4159562, -0.09236754, 0.1401497, 0.1881913, -0.03340681, -0.02385308, 0.1942524, -0.2044283, -0.07496213, -0.1248668, -0.526019, 0.24912, -0.4293477, -0.1057563, 0.5351143, 0.2214067, 0.07939806, ...
The yearly rate of Relative Thalamic Atrophy (yrRTA): a simple 2D/3D method for estimating deep gray matter atrophy in Multiple Sclerosis.
Despite a strong correlation to outcome, the measurement of gray matter (GM) atrophy is not being used in daily clinical practice as a prognostic factor and monitor the effect of treatments in Multiple Sclerosis (MS). This is mainly because the volumetric methods available to date are sophisticated and difficult to imp...
25,206,331
[ 0.1899894, -0.08437062, 0.2273363, -0.119169, 0.1816371, -0.4011449, 0.197971, 0.07287022, -0.1531891, -0.2128348, -0.1746293, -0.194416, 0.152937, 0.1284795, -0.6704722, -0.02389162, 0.08238964, 0.04786761, -0.04317131, -0.0543747, 0.145585, 0.3242124, -0.2642799, 0.20...
Spontaneous recovery of cochlear fibrocytes after severe degeneration caused by acute energy failure.
Cochlear fibrocytes in the lateral wall region play a critical role in the regulation of inner ear ion and fluid homeostasis, although these are non-sensory cells. Along with other non-sensory cells, fibrocytes in the spiral ligament have been reported to repopulate themselves after damage. However, the studies of rege...
25,206,337
[ -0.4253973, -0.1402512, -0.02179527, 0.09095024, 0.04106642, -0.5247225, 0.1161296, -0.1656156, 0.2732, -0.01486653, -0.2294384, -0.003322846, -0.2197007, 0.3827896, -0.185676, -0.02046328, -0.2776078, -0.2000988, -0.2666901, -0.3094052, -0.07489669, -0.04504332, -0.19398...
Epigenetic regulation of the neural transcriptome and alcohol interference during development.
Alcohol intoxicated cells broadly alter their metabolites - among them methyl and acetic acid can alter the DNA and histone epigenetic codes. Together with the promiscuous effect of alcohol on enzyme activities (including DNA methyltransferases) and the downstream effect on microRNA and transposable elements, alcohol i...
25,206,361
[ -0.3635373, -0.1384417, -0.1439288, -0.1656553, 0.1160945, -0.09512392, -0.3448656, 0.0594161, 0.05818776, 0.2848541, 0.01522688, 0.0711227, 0.09352436, -0.03134663, -0.1771779, 0.2267763, -0.4462398, 0.2035, -0.1588464, -0.08937356, 0.2781742, 0.2937891, -0.3187116, -0...
Autophagy activator promotes neuronal differentiation of adult adipose-derived stromal cells.
Preliminary research from our group found altered autophagy intensity during adipose-derived stromal cell differentiation into neuronal-like cells, and that this change was associated with morphological changes in differentiated cells. This study aimed to verify the role of rapamycin, an autophagy activator, in the pro...
25,206,379
[ -0.007878605, 0.009035182, -0.1700087, -0.04277195, 0.1468992, -0.2797963, 0.009531293, 0.08133976, 0.2623768, 0.1092804, -0.1801025, -0.09291239, 0.4577523, 0.1845564, -0.05245109, 0.2549876, -0.3566431, 0.1790611, -0.2106803, 0.3760268, -0.05360642, 0.1613766, -0.065572...
Effect of minocycline on cerebral ischemia-reperfusion injury.
Minocylcine, a tetracycline derivate, has been shown to cross the blood-brain barrier and enter the central nervous system. In this study, cerebral ischemia-reperfusion injury models were established using the suture method, and minocycline was immediately injected intraperitoneally after cerebral ischemia-reperfusion ...
25,206,381
[ -0.1701708, 0.09138415, -0.02107528, -0.2139743, -0.04675539, -0.2732287, 0.02341554, -0.1063115, 0.2466744, 0.1548213, 0.1023766, 0.5438676, -0.0235088, 0.2558496, -0.2042224, 0.01958711, -0.2869886, 0.4643166, -0.4459073, 0.2236734, 0.3631775, 0.08010064, 0.171676, -0...
Therapeutic effects and safety of olcegepant and telcagepant for migraine: A meta-analysis.
To evaluate the therapeutic effects and adverse reactions of olcegepant and telcagepant for the treatment of migraine. We identified studies using Medline (1966-01/2012-06), PubMed (1966-01/2012-06), Scopus (1980-01/2012-06), Cochrane Central Register of Controlled Trials (1980-01/2012-06) and China National Knowledge ...
25,206,386
[ 0.004182018, 0.2300329, -0.107458, -0.1246205, 0.2168292, -0.2830695, -0.2193082, -0.09936982, 0.1061821, -0.4928481, 0.06392789, 0.2012074, 0.1873936, -0.06409182, -0.187364, -0.2505053, -0.3880233, 0.3509301, -0.1320952, 0.2242418, -0.1512129, 0.1905255, -0.2202273, 0...
Amniotic membrane covering for facial nerve repair.
Amniotic membranes have been widely used in ophthalmology and skin injury repair because of their anti-inflammatory properties. In this study, we measured therapeutic efficacy and determined if amniotic membranes could be used for facial nerve repair. The facial nerves of eight rats were dissected and end-to-end anasto...
25,206,390
[ -0.1329729, -0.1234641, -0.3913618, -0.353137, 0.05548343, -0.1153963, -0.4028896, 0.2534574, 0.349871, -0.2963606, -0.1111338, -0.2606171, 0.2785287, -0.1069529, -0.01014935, -0.03599535, -0.3119247, 0.07161444, -0.2367048, 0.1605655, 0.2416128, 0.03783309, -0.1509214, ...
Wall shear stress in intracranial aneurysms and adjacent arteries.
Hemodynamic parameters play an important role in aneurysm formation and growth. However, it is difficult to directly observe a rapidly growing de novo aneurysm in a patient. To investigate possible associations between hemodynamic parameters and the formation and growth of intracranial aneurysms, the present study cons...
25,206,394
[ -0.3394471, 0.2507595, -0.08692782, 0.1328078, 0.1714062, -0.2898737, -0.1255184, 0.01851009, 0.2406953, 0.2653103, 0.0123643, -0.1631882, -0.5107277, -0.3952644, 0.0242855, 0.0680424, -0.2200992, 0.1810402, -0.09890591, 0.06304261, 0.3023837, -0.05027748, -0.07316198, ...
Optimal electroacupuncture frequency for maintaining astrocyte structural integrity in cerebral ischemia.
The astrocyte is a critical regulator of neuronal survival after ischemic brain injury. Electroacupuncture may be an effective therapy for cerebral ischemia, as electroacupuncture frequency can affect the structural integrity of astrocytes. In this study, a rat model of middle cerebral artery occlusion established usin...
25,206,406
[ 0.2936304, 0.5381898, 0.04864297, 0.1093174, 0.0314764, -0.3689868, -0.3457443, -0.2689362, -0.03383317, -0.2052761, -0.2145371, 0.3054237, -0.2696949, -0.3692175, -0.1623361, -0.3344015, -0.4096947, 0.174578, -0.4311948, -0.01188246, -0.02888729, 0.2314038, 0.01760607, ...
Stem cell properties and neural differentiation of sheep amniotic epithelial cells.
This study was designed to verify the stem cell properties of sheep amniotic epithelial cells and their capacity for neural differentiation. Immunofluorescence microscopy and reverse transcription-PCR revealed that the sheep amniotic epithelial cells were positive for the embryonic stem cell marker proteins SSEA-1, SSE...
25,206,415
[ 0.1188796, -0.3731844, -0.2970825, -0.1738242, 0.04093109, -0.2923161, -0.1783866, -0.05567711, -0.09499978, 0.1491221, 0.0926455, 0.2504219, 0.3007936, 0.1433394, -0.08359527, -0.08857746, -0.5716566, 0.2107474, -0.317804, -0.01109563, 0.391446, 0.4803478, -0.1552357, ...
Communicating with the non-dominant hemisphere: Implications for neurological rehabilitation.
Aphasic syndromes usually result from injuries to the dominant hemisphere of the brain. Despite the fact that localization of language functions shows little interindividual variability, several brain areas are simultaneously activated when language tasks are undertaken. Mechanisms of language recovery after brain inju...
25,206,418
[ -0.2787111, 0.08404716, 0.2325585, -0.2932855, 0.3077637, -0.2830237, -0.008877127, -0.1559635, -0.01221962, 0.3530642, -0.1136662, 0.1261679, -0.4034505, -0.2903529, 0.1297013, -0.3534307, -0.08827795, 0.07548448, -0.4857875, -0.2115526, 0.006886475, 0.1349172, -0.002646...
Changes of brain gray matter structure in Parkinson's disease patients with dementia.
Voxel-based morphometry is gaining considerable interest for studies examining Parkinson's disease dementia patients. In this study, 12 patients with clinically defined Parkinson's disease and dementia and 12 non-demented patients with Parkinson's disease were examined using a T1WI three-dimensional fast spoiled gradie...
25,206,422
[ -0.02253515, 0.04291623, 0.2040444, 0.1712418, 0.1750143, -0.2325033, 0.4348102, -0.2834343, -0.1877419, 0.3195773, 0.05912661, -0.1044912, -0.2381902, 0.009932134, -0.5153211, 0.2868587, 0.07592541, 0.4567511, -0.1593841, -0.1600344, -0.2625721, 0.2832251, -0.0971936, ...
Olfactory ensheathing cell transplantation for spinal cord injury: An 18-year bibliometric analysis based on the Web of Science.
Olfactory ensheathing cell (OEC) transplantation is a promising new approach for the treatment of spinal cord injury (SCI), and an increasing number of scientific publications are devoted to this treatment strategy. This bibliometric analysis was conducted to assess global research trends in OEC transplantation for SCI...
25,206,423
[ 0.02474653, -0.1295248, 0.2926485, -0.03161485, 0.1453758, -0.02686546, -0.3020709, 0.0157843, 0.001043773, -0.1283787, -0.07176759, -0.06637546, 0.08931535, 0.1178124, -0.2183731, -0.1138632, 0.07585965, 0.139662, -0.1741926, 0.05939993, -0.2377966, 0.5806029, 0.1324348,...
Persimmon leaf flavonoid induces brain ischemic tolerance in mice.
The persimmon leaf has been shown to improve cerebral ischemic outcomes; however, its mechanism of action remains unclear. In this study, mice were subjected to 10 minutes of ischemic preconditioning, and persimmon leaf flavonoid was orally administered for 5 days. Results showed that the persimmon leaf flavonoid signi...
25,206,432
[ -0.2109569, 0.2632468, -0.3836415, 0.04266654, 0.07302339, 0.2219413, 0.1832626, -0.03366204, 0.162497, -0.2839937, -0.1370513, 0.4325375, -0.225306, -0.06328782, -0.3521889, 0.04481474, -0.2154288, 0.07346925, 0.1306514, 0.2816247, 0.04819269, 0.4149296, -0.09564023, -...
Auditory event-related brain potentials for an early discrimination between normal and pathological brain aging.
The brain as a system with gradually decreasing resources maximizes its chances by reorganizing neural networks to ensure efficient performance. Auditory event-related potentials were recorded in 28 healthy volunteers comprising 14 young and 14 elderly subjects in auditory discrimination motor task (low frequency tone ...
25,206,434
[ 0.09964214, -0.01935668, -0.1161671, -0.2272975, 0.1457387, -0.4846193, -0.2087494, 0.1246475, -0.2231035, 0.1507134, -0.3746939, -0.1715316, -0.1234007, -0.1385783, -0.3454272, -0.03824304, -0.5466956, 0.1781178, -0.3582708, -0.1468861, 0.185103, 0.2515551, -0.05431994, ...
Research progress in rehabilitation treatment of stroke patients: A bibliometric analysis.
Stroke presents as a transient or chronic brain dysfunction and is associated with high morbidity and high mortality. The doctors and scientists would like to argue how to enhance the validity of the rehabilitation treatment and how to further improve the level of treatment on stroke. The aim of this study was to quant...
25,206,438
[ 0.005895049, 0.279658, 0.1913777, 0.02295356, 0.03474747, 0.02891173, -0.1360765, 0.1575853, -0.08145157, -0.3138541, 0.1054104, 0.02243476, -0.2279646, 0.06326162, 0.201923, -0.01859618, 0.07941826, 0.2250513, -0.2461632, 0.1386444, -0.2096331, 0.3163719, 0.04437141, -...
The top cited articles on glioma stem cells in Web of Science.
Glioma is the most common intracranial tumor and has a poor patient prognosis. The presence of brain tumor stem cells was gradually being understood and recognized, which might be beneficial for the treatment of glioma. To use bibliometric indexes to track study focuses on glioma stem cell, and to investigate the relat...
25,206,439
[ -0.1534918, -0.07854429, 0.1134827, -0.1940057, 0.2249071, 0.07533254, -0.1500902, 0.3813581, -0.01677587, 0.2297244, -0.1012562, 0.120873, -0.1781772, -0.02794073, -0.3219196, 0.009248885, 0.3431924, 0.2378468, -0.07272589, -0.05909202, 0.198446, 0.3347647, -0.07662532, ...
JNK3 involvement in nerve cell apoptosis and neurofunctional recovery after traumatic brain injury.
Increasing evidence has revealed that the activation of the JNK pathway participates in apoptosis of nerve cells and neurological function recovery after traumatic brain injury. However, which genes in the JNK family are activated and their role in traumatic brain injury remain unclear. Therefore, in this study, in sit...
25,206,445
[ -0.06608009, -0.03581702, -0.05540305, -0.279375, -0.02931799, -0.2088859, -0.101736, 0.06676789, -0.1712362, 0.180738, 0.1309385, -0.1732859, -0.1523241, -0.01501696, -0.07236186, -0.3385048, -0.1795829, 0.4201088, -0.2902693, 0.2716861, 0.06728775, 0.308787, 0.03960241,...
Routine exposure of recurrent laryngeal nerve in thyroid surgery can prevent nerve injury.
To determine the value of dissecting the recurrent laryngeal nerve during thyroid surgery with respect to preventing recurrent laryngeal nerve injury, we retrospectively analyzed clinical data from 5 344 patients undergoing thyroidectomy. Among these cases, 548 underwent dissection of the recurrent laryngeal nerve, whi...
25,206,452
[ -0.08599022, -0.3552986, -0.3248134, -0.3517981, -0.1458089, -0.3517272, -0.1538677, 0.1602903, 0.06207362, 0.3196576, 0.3567397, 0.02140522, -0.1879185, -0.5700273, 0.2726599, -0.003958464, -0.08738339, 0.2915227, 0.09764553, 0.04002532, 0.09247106, 0.3951454, -0.2785093...
X-irradiation for inhibiting glial scar formation in injured spinal cord.
X-irradiation has a beneficial effect in treating spinal cord injury. We supposed that X-irradiation could improve the microenvironment at the site of a spinal cord injury and inhibit glial scar formation. Thus, this study was designed to observe the effects of 8 Gy X-irradiation on the injury site at 6 hours and 2, 4,...
25,206,454
[ 0.457811, 0.3990165, 0.008504585, 0.0692425, -0.02501272, -0.3738465, -0.2396697, -0.2106135, -0.158576, 0.01880667, -0.05136647, -0.02266648, 0.007850535, -0.07199939, -0.4540858, -0.4024298, -0.1491899, 0.3017021, -0.0409055, 0.1446009, -0.2400259, 0.4489453, 0.162323, ...
A ginkgo biloba extract promotes proliferation of endogenous neural stem cells in vascular dementia rats.
The ginkgo biloba extract EGb761 improves memory loss and cognitive impairments in patients with senile dementia. It also promotes proliferation of neural stem cells in the subventricular zone in Parkinson's disease model mice and in the hippocampal zone of young epileptic rats. However, it remains unclear whether EGb7...
25,206,462
[ -0.08844024, -0.1284519, -0.2516452, -0.1982615, 0.2570375, -0.0904097, 0.1398498, -0.5376933, 0.04728471, 0.04726384, -0.07174165, 0.5776604, -0.2690065, -0.2363875, 0.04750696, 0.495268, -0.4943382, 0.3946563, -0.3405666, 0.3621243, -0.1697801, 0.4024521, 0.07581463, ...
Adenosine triphosphate promotes locomotor recovery after spinal cord injury by activating mammalian target of rapamycin pathway in rats.
The mammalian target of rapamycin (mTOR) pathway plays an important role in neuronal growth, proliferation and differentiation. To better understand the role of mTOR pathway involved in the induction of spinal cord injury, rat models of spinal cord injury were established by modified Allen's stall method and interfered...
25,206,479
[ 0.2313358, 0.2130182, 0.07987488, -0.08620491, 0.1015313, -0.599281, -0.382571, 0.1052805, -0.04318966, -0.1885333, -0.1746867, -0.06533095, -0.05952841, 0.07062563, 0.08845927, -0.2443775, -0.3478129, 0.04955511, -0.3235244, -0.1417456, -0.09414579, 0.138828, -0.00405318...
8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury.
Previous studies have reported a neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) against traumatic brain injury. In accordance with the Marmarou method, rat models of diffuse axonal injury were established. 8-OH-DPAT was intraperitoneally injected into model rats. 8-OH-DPAT treated rats mai...
25,206,483
[ -0.1154076, -0.1828247, -0.2961364, -0.1918218, 0.1437156, -0.265615, 0.02651702, -0.03309884, 0.2510141, -0.1076399, 0.1147301, 0.1505721, 0.1352037, -0.05651875, -0.2402223, -0.2915571, -0.2499606, 0.4737583, -0.09202848, 0.3480375, 0.1708422, 0.5134352, -0.03889169, ...
Kisspeptin regulates gonadotropin-releasing hormone secretion in gonadotropin-releasing hormone/enhanced green fluorescent protein transgenic rats.
Kisspeptin is essential for activation of the hypothalamo-pituitary-gonadal axis. In this study, we established gonadotropin-releasing hormone/enhanced green fluorescent protein transgenic rats. Rats were injected with 1, 10, or 100 pM kisspeptin-10, a peptide derived from full-length kisspeptin, into the arcuate nucle...
25,206,487
[ 0.1297501, -0.03012064, -0.257011, -0.265188, 0.2416521, -0.00995359, 0.002773513, 0.04687326, 0.05897968, 0.09006207, 0.2289598, 0.2303244, -0.09027179, -0.06606169, -0.2630359, -0.1605678, -0.4223934, 0.3906948, 0.136107, -0.2800859, 0.1710051, 0.2708378, 0.02963026, ...
A three-dimensional digital visualization model of cervical nerves in a healthy person.
Three-dimensional reconstruction nerve models are classically obtained from two-dimensional ages of "visible human" frozen sections. However, because of the flexibility of nerve tissues and small color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during mill...
25,206,491
[ -0.1564538, 0.3193893, -0.3011369, 0.2247345, -0.04475184, -0.2929659, -0.2300394, 0.2666964, 0.4345686, -0.2029291, 0.1354727, -0.1199831, 0.07746705, -0.141627, -0.4585131, -0.260923, -0.3116491, 0.1015563, -0.5667976, -0.09783907, 0.3929374, 0.4191265, -0.3063967, 0....
Processing Chinese hand-radicals activates the medial frontal gyrus: A functional MRI investigation.
Embodied semantics theory asserts that the meaning of action-related words is neurally represented through networks that overlap with or are identical to networks involved in sory-motor processing. While some studies supporting this theory have focused on Chinese characters, less attention has been paid to their semant...
25,206,492
[ -0.07536007, 0.3134728, 0.03300616, -0.09867991, 0.4743664, 0.1052876, -0.1176819, -0.1991609, -0.09529066, 0.1970465, -0.1446405, -0.1283591, -0.2232496, -0.1169143, -0.3983718, -0.05550044, -0.5081373, 0.1219086, -0.1927158, 0.1065642, 0.2101756, 0.2155107, 0.001858024,...
Cell cycle-related genes p57kip2, Cdk5 and Spin in the pathogenesis of neural tube defects.
In the field of developmental neurobiology, accurate and ordered regulation of the cell cycle and apoptosis are crucial factors contributing to the normal formation of the neural tube. Preliminary studies identified several genes involved in the development of neural tube defects. In this study, we established a model ...
25,206,495
[ 0.09530615, 0.02480754, 0.06293905, 0.04493658, 0.0890959, 0.05200005, 0.01261946, -0.02684382, 0.1306974, 0.1528217, 0.3391837, 0.2053839, -0.1739039, 0.01510454, -0.2258103, 0.1889631, -0.4203339, -0.1583678, -0.188228, -0.1165186, 0.7780999, 0.3316197, -0.09789786, 0...
Motor outcomes of patients with a complete middle cerebral artery territory infarct.
Detailed knowledge of motor outcomes enables to establish proper goals and rehabilitation strategies for stroke patients. Several previous studies have reported functional or motor outcomes in patients with a middle cerebral artery territory infarct. However, little is known about motor outcome in patients with a compl...
25,206,498
[ -0.3473321, 0.4407628, 0.06426551, -0.3085171, -0.1239178, -0.2454419, -0.1655369, -0.1079099, -0.269916, 0.110423, -0.3448448, -0.3635988, -0.003430428, -0.5615559, -0.07920759, 0.1069301, -0.3000476, 0.1748735, -0.4811462, -0.2827079, -0.2958262, -0.1893388, 0.2763036, ...
Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment.
The Chinese herb Shuyusan, whose main constituent is jasminoidin, has been shown to protect SH-SY5Y cells against corticosterone-induced damage. SH-SY5Y cells injured by 400 μmol/L corticosterone were treated with 5 and 30 μg/mL Shuyusan-containing serum. Results revealed that Shuyusan-containing serum elevated the sur...
25,206,514
[ -0.2250206, -0.08067139, 0.2924403, -0.4766756, 0.3300976, 0.175108, -0.4132351, -0.02976811, 0.2055201, 0.1626632, 0.3138341, -0.00103995, 0.03611795, 0.02583864, -0.1241876, -0.0375517, 0.01897063, 0.1231516, 0.1675981, 0.7094007, 0.2511066, 0.1842172, -0.1197693, -0....
Morphology of platelet Golgi apparatus and their significance after acute cerebral infarction.
Blood samples were harvested from the antecubital vein of 20 fasting patients with acute cerebral infarction at 1, 7 and 15 days after onset to prepare blood platelet suspension. Fasting antecubital vein blood was collected from an additional 20 normal adults as controls. Under transmission tron microscope, platelet Go...
25,206,522
[ 0.2183196, 0.2723515, -0.4473939, 0.05495794, 0.2840385, -0.3847599, 0.109978, -0.144302, -0.08421706, 0.2170719, -0.05185846, 0.1735739, -0.1111228, -0.1505143, 0.02373857, -0.1201242, -0.3902102, -0.1109986, 0.01967471, 0.3228796, 0.3210081, 0.4286782, -0.1002184, 0.1...
Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction.
From pregnancy to parturition, Sprague-Dawley rats were daily administered a low protein diet to establish a model of intrauterine growth restriction. From the 12(th) day of pregnancy, 300 mg/kg rine was daily added to food until spontaneous delivery occurred. Brain tissues from normal neonatal rats at 6 hours after de...
25,206,528
[ -0.1642875, -0.05527222, 0.2005484, 0.1279463, 0.4647232, -0.4669653, 0.09105383, -0.2782569, 0.1941558, -0.08883546, -0.09536678, 0.6026007, -0.08149927, 0.2012516, -0.09513164, 0.1672505, -0.8144842, 0.3533992, -0.3673788, 0.09910057, 0.044656, 0.9076104, 0.01345939, ...
Buyang Huanwu Decoction regulates neural stem cell behavior in ischemic brain.
The traditional Chinese medicine Buyang Huanwu Decoction has been shown to improve the neu-rological function of patients with stroke. However, the precise mechanisms underlying its effect remain poorly understood. In this study, we established a rat model of cerebral ischemia by middle cerebral artery occlusion and in...
25,206,543
[ 0.110842, -0.01967247, -0.009622728, -0.2779249, 0.3499752, -0.382117, -0.2342952, -0.005136971, 0.5037807, 0.5302759, -0.1565661, 0.1402193, -0.0874951, -0.2992516, -0.2713565, 0.2446715, -0.3412105, 0.2197083, -0.3863145, 0.445853, -0.07569612, 0.4278167, -0.08781832, ...
miR-137, a new target for post-stroke depression?
Expression of miR-137 is downregulated in brain tissue from patients with depression and suicidal behavior, and is also downregulated in peripheral blood from stroke patients. However, it is not yet known if miR-137 acts as a bridge between stroke and depression. To test this, we used middle cerebral artery occlusion a...
25,206,554
[ 0.08249044, 0.07654528, -0.1098763, -0.4357888, 0.2296208, 0.2622585, -0.1026434, 0.03448473, -0.2392845, 0.002547066, -0.09221226, 0.2755974, -0.04283759, 0.08291293, -0.055783, 0.04853704, -0.1510547, 0.1843455, 0.1790828, 0.2964206, -0.1963538, 0.03387141, 0.1395147, ...
Imaging and clinical properties of inflammatory demyelinating pseudotumor in the spinal cord.
Inflammatory demyelinating pseudotumor usually occurs in the brain and rarely occurs in the spinal cord. On imaging, inflammatory demyelinating pseudotumor appears very similar to intramedullary tumors such as gliomas. It is often misdiagnosed as intramedullary tumor and surgically resected. In view of this, the clinic...
25,206,559
[ 0.003648998, -0.1377088, 0.01058659, -0.1407323, -0.04134019, -0.4042327, -0.2236606, 0.06561624, 0.02504857, 0.2122912, -0.1336678, 0.2516529, 0.2639107, 0.3815246, -0.3587357, 0.1625334, -0.03261039, 0.003235318, -0.1586386, -0.09569163, -0.006597496, -0.09558151, -0.13...
Propofol's effect on the sciatic nerve: Harmful or protective?
Propofol can inhibit the inflammatory response and reduce the secretion and harmful effects of astrocyte-derived proinflammatory cytokines. In this study, after propofol was injected into the injured sciatic nerve of mice, nuclear factor kappa B expression in the L4-6 segments of the spinal cord in the injured side was...
25,206,562
[ 0.05100249, -0.1325485, -0.1879297, 0.05147899, -0.03718406, -0.1645792, -0.03926982, 0.09803433, -0.2213802, -0.2985566, -0.1152, 0.1384701, -0.01413575, 0.08720463, 0.1564846, -0.2557391, -0.4814028, 0.3159434, -0.3983202, 0.2838024, -0.009840336, 0.1500239, 0.06062141,...
Buyang Huanwu Decoction fraction protects against cerebral ischemia/reperfusion injury by attenuating the inflammatory response and cellular apoptosis.
Buyang Huanwu Decoction fraction extracted from Buyang Huanwu Decoction contains saponins of Astragalus, total paeony glycoside and safflower flavones. The aim of this study was to demonstrate the neuroprotective effect and mechanism of Buyang Huanwu Decoction fraction on ischemic injury both in vivo and in vitro. In v...
25,206,589
[ -0.1363332, -0.04598199, -0.1829124, 0.07351645, 0.2970626, -0.3407841, 0.1468389, 0.09218815, -0.1307582, 0.2897963, -0.144949, 0.3444787, -0.2487123, -0.4330286, -0.02739065, 0.1510543, -0.1769502, 0.3691513, -0.4486752, 0.7453668, 0.1418481, 0.2176049, -0.3152548, -0...
Correlation between the cumulative analgesic effect of electroacupuncture intervention and synaptic plasticity of hypothalamic paraventricular nucleus neurons in rats with sciatica.
In the present study, a rat model of chronic neuropathic pain was established by ligation of the sciatic nerve and a model of learning and memory impairment was established by ovariectomy to investigate the analgesic effect of repeated electroacupuncture stimulation at bilateral Zusanli (ST36) and Yanglingquan (GB34). ...
25,206,591
[ 0.3080392, 0.4585434, -0.03013372, -0.017306, -0.4365019, -0.55387, -0.2328364, -0.1462169, 0.27123, 0.02740681, -0.01365435, 0.03403074, -0.2598917, -0.316106, -0.2172145, -0.11866, -0.3455493, 0.2577788, -0.05359273, 0.02208226, -0.4101812, 0.231163, 0.00872934, 0.200...
Back propagation artificial neural network for community Alzheimer's disease screening in China.
Alzheimer's disease patients diagnosed with the Chinese Classification of Mental Disorders diagnostic criteria were selected from the community through on-site sampling. Levels of macro and trace elements were measured in blood samples using an atomic absorption method, and neurotransmitters were measured using a radio...
25,206,598
[ -0.2355114, -0.07159487, -0.1362656, 0.17243, -0.307808, -0.2484194, -0.3701135, 0.1139864, 0.03620881, -0.07305143, 0.06750485, 0.07314721, 0.5592946, 0.3507154, -0.2205875, 0.0151547, -0.5266517, 0.06974673, -0.01382903, 0.1934413, 0.2133977, 0.33999, 0.04713154, 0.11...
Viscoelastic evaluation of fetal umbilical vein for reconstruction of middle cerebral artery.
The transplantation of artificial blood vessels with < 6 mm inner diameter as substitutes for human arterioles or veins has not achieved satisfactory results. Umbilical vein has been substituted for ar-tery in vascular transplantation, but it remains unclear whether the stress relaxation and creep tween these vessel...
25,206,626
[ -0.1071629, 0.01176869, -0.3823181, 0.2004417, 0.14855, 0.107663, -0.2498717, 0.2581843, 0.2176924, 0.09644045, 0.22453, 0.04632408, -0.08368039, -0.1021415, -0.4041666, -0.1261678, -0.2448956, 0.02325702, -0.6203935, 0.5333585, 0.5492499, 0.129833, 0.09744012, -0.13056...
Targeting β-secretase with RNAi in neural stem cells for Alzheimer's disease therapy.
There are several major pathological changes in Alzheimer's disease, including apoptosis of cholinergic neurons, overactivity or overexpression of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) and inflammation. In this study, we synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid...
25,206,630
[ -0.1060912, -0.1156821, 0.05380246, -0.150677, -0.05249184, 0.05433264, -0.2931746, 0.08899403, 0.1835166, 0.3266294, 0.07473174, -0.1986689, -0.03511762, 0.3028299, -0.3895751, 0.2169852, -0.394833, 0.1725105, -0.2447517, 0.2512432, 0.2491808, 0.2176715, 0.01319516, -0...
Puerarin partly counteracts the inflammatory response after cerebral ischemia/reperfusion via activating the cholinergic anti-inflammatory pathway.
Puerarin, a major isoflavonoid derived from the Chinese medical herb radix puerariae (Gegen), has been reported to inhibit neuronal apoptosis and play an anti-inflammatory role in focal cerebral ischemia model rats. Recent findings regarding stroke pathophysiology have recognized that anti-inflammation is an important ...
25,206,641
[ 0.01951787, 0.2087286, -0.3754078, -0.3264553, 0.3682727, -0.09371478, 0.1799852, -0.1502449, -0.09017981, -0.009193481, 0.1818486, 0.556559, -0.06565932, -0.3028322, -0.2120143, 0.1849902, -0.1874369, 0.3556412, 0.1775443, 0.1690946, 0.2947558, 0.1669982, 0.05827926, -...
Hyperbaric oxygen therapy improves cognitive functioning after brain injury.
Hyperbaric oxygen therapy has been widely applied and recognized in the treatment of brain injury; however, the correlation between the protective effect of hyperbaric oxygen therapy and changes of metabolites in the brain remains unclear. To investigate the effect and potential mechanism of hyperbaric oxygen therapy o...
25,206,655
[ 0.08315669, 0.06359301, 0.02850394, 0.1375368, -0.05541797, -0.4128097, -0.04235096, -0.03918888, -0.1514993, 0.3978307, -0.005423231, 0.5199653, 0.09324453, 0.1159084, 0.1314133, -0.1363317, -0.01313165, 0.1120741, -0.4661758, 0.1474962, -0.246958, -0.01913102, 0.2666473...
Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury.
Emerging studies of treating spinal cord injury (SCI) with adult stem cells led us to evaluate the effects of transplantation of hair follicle stem cells in rats with a compression-induced spinal cord lesion. Here, we proposed a hypothesis that rat hair follicle stem cell transplantation can promote the recovery of inj...
25,206,658
[ 0.2906054, -0.165857, 0.09060246, 0.1558037, 0.0599672, -0.4144065, -0.2233651, 0.04231384, -0.07808119, 0.008777125, -0.2101926, -0.06328374, -0.1004942, 0.3765852, 0.02389243, -0.2618851, -0.445843, -0.01078935, -0.3327975, -0.1229507, -0.2967512, 0.3504978, 0.1928442, ...
Does diffusion tensor data reflect pathological changes in the spinal cord with chronic injury.
Magnetic resonance diffusion tensor imaging has been shown to quantitatively measure the early pathological changes in chronic cervical spondylotic myelopathy. In this study, a novel spongy polyurethane material was implanted in the rat C3-5 epidural space to establish a rat model of chronic cervical spondylotic myelop...
25,206,660
[ 0.0007019237, 0.03880148, 0.09124491, 0.371367, 0.02129366, -0.4095993, 0.04533949, 0.06326488, 0.1008716, 0.2771203, 0.1228158, 0.1395735, 0.07462388, 0.0145471, -0.007696763, -0.09441406, 0.02244041, 0.101723, -0.687089, 0.1123108, 0.10284, 0.3665607, 0.169011, 0.3817...
Immediate versus delayed primary nerve repair in the rabbit sciatic nerve.
It is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed (3 days after injury) neurorrhaphy on repair of transected sciatic nerve in New Zealand rabbits using stereological, hi...
25,206,663
[ 0.01164577, -0.2175927, -0.2672973, -0.001105407, -0.1894017, -0.4910351, -0.117445, -0.03547966, -0.001483351, 0.1670748, 0.08959451, -0.04238858, -0.105588, -0.2206004, -0.1840703, -0.3158896, -0.2450652, 0.1244201, -0.4120874, -0.04595054, 0.1376202, 0.1686905, 0.13988...
Angiogenin gene polymorphism: A risk factor for diabetic peripheral neuropathy in the northern Chinese Han population.
Angiogenin is associated with the pathogenesis of diabetic peripheral neuropathy. Here, we quenced the coding region of the angiogenin gene in genomic DNA from 207 patients with type 2 diabetes mellitus (129 diabetic peripheral neuropathy patients and 78 diabetic non-neuropathy patients) and 268 healthy controls. All s...
25,206,666
[ -0.1395382, -0.01929096, 0.06480956, 0.08377585, -0.03342074, -0.03974388, -0.241388, -0.1291927, 0.3663058, 0.0507105, 0.03682734, 0.08579689, 0.06888451, -0.1754013, 0.208534, -0.2831097, -0.192383, -0.05985161, 0.0869147, -0.05782139, -0.2747386, 0.3325248, 0.07608394,...
Differentiation of neuron-like cells from mouse parthenogenetic embryonic stem cells.
Parthenogenetic embryonic stem cells have pluripotent differentiation potentials, akin to fertilized embryo-derived embryonic stem cells. The aim of this study was to compare the neuronal differentiation potential of parthenogenetic and fertilized embryo-derived embryonic stem cells. Before differentiation, karyotype a...
25,206,669
[ 0.2545569, -0.1467251, -0.2712059, -0.07928256, 0.3448771, -0.3516366, -0.2710571, 0.01974835, 0.2041225, 0.1604561, -0.06392372, 0.4037552, 0.08176932, 0.3198107, 0.04782529, 0.05702247, -0.5153828, 0.09511705, -0.3814237, -0.01286661, 0.05584272, 0.242224, 0.07837052, ...
Optimal time for subarachnoid transplantation of neural progenitor cells in the treatment of contusive spinal cord injury.
This study aimed to identify the optimal neural progenitor cell transplantation time for spinal cord injury in rats via the subarachnoid space. Cultured neural progenitor cells from 14-day embryonic rats, constitutively expressing enhanced green fluorescence protein, or media alone, were injected into the subarachnoid ...
25,206,679
[ 0.1234472, 0.172509, -0.08501842, 0.1991121, 0.04266227, -0.4411156, -0.3090172, -0.006774892, -0.03541436, -0.1391318, -0.2153916, -0.05210265, -0.1185249, 0.1661424, -0.09787817, -0.1232936, -0.4936683, -0.03598624, -0.1700739, -0.100591, 0.06858113, 0.5663598, 0.206223...
Brain imaging of mild cognitive impairment and Alzheimer's disease.
The rapidly increasing prevalence of cognitive impairment and Alzheimer's disease has the potential to create a major worldwide healthcare crisis. Structural MRI studies in patients with Alzheimer's disease and mild cognitive impairment are currently attracting considerable interest. It is extremely important to study ...
25,206,685
[ -0.1073036, 0.1997467, 0.1447635, -0.1951229, -0.1044073, -0.1190909, -0.04379067, -0.06664695, -0.1083689, 0.2438828, -0.1238871, -0.1646009, -0.1058056, 0.2683859, -0.1851756, 0.0847652, -0.1318558, 0.5535637, -0.02033173, -0.04578415, -0.07119752, 0.3666329, -0.0565459...
Therapeutic benefit of repetitive transcranial magnetic stimulation for severe mirror movements: A case report.
Congenital mirror movements retard typical hand functions, but no definite therapeutic modality is available to treat such movements. We report an 8-year-old boy with severe mirror movements of both hands. His mirror movements were assessed using the Woods and Teuber grading scale and his fine motor skills were also ev...
25,206,701
[ -0.01527231, 0.04538382, -0.0613001, -0.4257638, 0.2395378, -0.3101685, -0.03958506, 0.06774572, -0.127657, 0.1990299, -0.1097753, 0.2667592, -0.4957519, -0.1867284, -0.201976, 0.02178089, -0.4234583, 0.09242991, -0.4063382, -0.1628576, 0.1682407, 0.165703, 0.0857665, 0...
Brilliant blue G attenuates lipopolysaccharide-mediated microglial activation and inflammation.
Previous studies have confirmed that oxidized adenosine triphosphate, a P2X7 receptor antagonist, attenuates lipopolysaccharide-mediated microglial activation and inflammatory expression following neuronal damage in rat brain. NaCl and temperature may affect the potency of oxidized adenosine triphosphate. Brilliant blu...
25,206,704
[ 0.0876931, 0.2914701, -0.1472488, 0.1049342, 0.1174742, 0.1274395, -0.1084124, 0.07798016, -0.01561352, -0.4169627, 0.1904048, 0.2907156, -0.1093057, 0.1383135, -0.2000758, 0.1694078, -0.411398, 0.09999335, -0.1156057, -0.1570551, 0.1735547, 0.1339788, -0.003914454, 0.2...
Ischemic preconditioning reduces ischemic brain injury by suppressing nuclear factor kappa B expression and neuronal apoptosis.
Ischemic stroke induces a series of complex pathophysiological events including blood-brain barrier disruption, inflammatory response and neuronal apoptosis. Previous studies demonstrate that ischemic preconditioning attenuates ischemic brain damage via inhibiting blood-brain barrier disruption and the inflammatory res...
25,206,708
[ -0.02040311, 0.3950524, 0.06331073, -0.04015742, 0.01239802, -0.3408063, -0.1286331, -0.0662699, 0.07824548, 0.2337746, 0.1712566, 0.2354874, -0.2990572, -0.2038641, 0.4183109, -0.004348319, -0.4723663, 0.1054514, -0.2354193, 0.5729623, -0.1145645, 0.4328597, -0.04090943,...
A review on the coordinative structure of human walking and the application of principal component analysis.
Walking is a complex task which includes hundreds of muscles, bones and joints working together to deliver smooth movements. With the complexity, walking has been widely investigated in order to identify the pattern of multi-segment movement and reveal the control mechanism. The degree of freedom and dimensional proper...
25,206,712
[ -0.275133, 0.4142063, 0.03141204, 0.177118, 0.08840501, -0.4154364, -0.4757971, 0.08855383, 0.1436704, -0.1150418, 0.01030141, -0.3009997, -0.2253969, -0.1685454, -0.2404437, 0.1165073, -0.4406845, -0.04770264, -0.3918452, 0.09807599, -0.3766868, -0.06785218, -0.1709006, ...
Electroacupuncture diminishes P2X2 and P2X3 purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity.
Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic visceral hypersensitivity. Immunohistochemistry was used to detect P2X2 and P2X3 receptor expression in dorsal root ganglia from rats with chronic v...
25,206,727
[ 0.3348899, -0.3301115, 0.1268611, -0.01095144, 0.3663565, -0.2014083, -0.05860254, -0.2210423, 0.01189476, -0.006383873, 0.3104522, -0.3138267, -0.2649338, -0.3356859, 0.005404399, -0.3316001, -1.014068, 0.2738638, -0.3015704, 0.01149594, -0.3407544, 0.3993461, 0.2094393,...
Hippocampal gene expression in a rat model of depression after electroacupuncture at the Baihui and Yintang acupoints.
Preliminary basic research and clinical findings have demonstrated that electroacupuncture therapy exhibits positive effects in ameliorating depression. However, most studies of the underlying mechanism are at the single gene level; there are few reports regarding the mechanism at the whole-genome level. Using a rat ge...
25,206,746
[ 0.2450683, 0.06771645, -0.0852558, -0.1743631, 0.09525218, -0.3979847, -0.5024189, -0.0736898, -0.2325671, -0.0184746, 0.2218044, 0.4559093, -0.1584519, -0.4464309, -0.5377553, -0.1259767, -0.2438735, 0.3785619, -0.2191643, -0.2125398, -0.1443758, 0.3666298, -0.1867323, ...
Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease.
Amyloid-beta peptide is the main component of amyloid plaques, which are found in Alzheimer's disease. The generation and deposition of amyloid-beta is one of the crucial factors for the onset and progression of Alzheimer's disease. Lipid rafts are glycolipid-rich liquid domains of the plasma membrane, where certain ty...
25,206,748
[ -0.4664631, 0.0006576068, 0.03111478, -0.109358, 0.2077672, -0.2654469, 0.008058078, 0.01108877, 0.1014671, 0.4221747, -0.01931026, -0.04402044, -0.08095191, 0.1976893, -0.01370315, 0.07421269, -0.4747491, 0.05343563, -0.06195751, -0.2210231, 0.223362, 0.46171, -0.2276766...
Critical illness polyneuropathy and myopathy: a systematic review.
Critical illness polyneuropathy and critical illness myopathy are frequent complications of severe illness that involve sensorimotor axons and skeletal muscles, respectively. Clinically, they manifest as limb and respiratory muscle weakness. Critical illness polyneuropathy/myopathy in isolation or combination increases...
25,206,749
[ -0.1935181, -0.2545638, -0.0180709, -0.3560332, -0.3294097, -0.03848676, -0.2904259, -0.0007740718, -0.03815832, -0.2115534, -0.1857848, -0.3447022, 0.04876825, 0.02701667, -0.03838347, -0.1474973, -0.6066723, 0.2050822, -0.00567566, -0.003540306, -0.392644, -0.05696063, ...
Attenuated inhibition of medium spiny neurons participates in the pathogenesis of childhood depression.
Accumulating evidence suggests that the nucleus accumbens, which is involved in mechanisms of reward and addiction, plays a role in the pathogenesis of depression and in the action of antidepressants. In the current study, intraperitoneal injection of nomifensine, a dopamine reuptake inhibitor, decreased depression-lik...
25,206,763
[ 0.06285685, 0.00741008, -0.1877355, 0.1308916, 0.1597747, -0.2887811, -0.4276752, -0.3847164, 0.01057779, 0.127617, 0.2568392, 0.260646, 0.03976081, 0.4058672, -0.001123417, 0.1325129, -0.04417583, 0.1683374, -0.1826083, -0.07304484, 0.1409628, -0.214536, 0.3434955, 0.1...
Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats.
Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia, and the role is mediated by the expression of mitochondrial proteins. This study investigated the involvement of mitochondrial proteins in hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats u...
25,206,771
[ -0.08514537, 0.2139615, 0.1135691, -0.06950317, 0.2012192, -0.3962623, 0.04511612, -0.01658625, 0.1900526, 0.2321218, 0.07864643, 0.5306158, -0.3169975, -0.09459681, -0.1025788, -0.04659511, -0.2592553, -0.03997846, -0.4392676, 0.1598822, -0.2635917, 0.3764125, 0.0605825,...
Autophagy: a double-edged sword for neuronal survival after cerebral ischemia.
Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether activation of autophagy increases or decreases the rate of neuronal death is still under debate. This review summarizes the potential role and possible signaling pathway of autophagy in neuronal survival after cerebral ischemia and...
25,206,784
[ -0.2109056, -0.1439751, 0.09817723, -0.3532006, 0.06945022, -0.141667, -0.09666299, -0.183245, -0.1622121, 0.06543335, -0.04230913, 0.4190599, -0.05538699, 0.1475388, -0.2329923, -0.2204196, -0.3215944, 0.2041119, -0.2523078, 0.3017879, 0.0527612, 0.3096786, -0.1267049, ...
Aspartic acid in the hippocampus: a biomarker for postoperative cognitive dysfunction.
This study established an aged rat model of cognitive dysfunction using anesthesia with 2% isoflurane and 80% oxygen for 2 hours. Twenty-four hours later, Y-maze test results showed that isoflurane significantly impaired cognitive function in aged rats. Gas chromatography-mass spectrometry results showed that isofluran...
25,206,795
[ -0.04469793, 0.04133631, -0.1012212, 0.06841128, 0.04048917, -0.01845368, -0.2938091, 0.2950337, 0.1002669, 0.2892714, 0.2944506, 0.2563137, 0.3552689, -0.1674877, 0.1784708, 0.2410785, -0.5846207, 0.351968, 0.03111115, 0.2837769, 0.01253888, 0.09052063, -0.01767904, 0....
Functional electrical stimulation-facilitated proliferation and regeneration of neural precursor cells in the brains of rats with cerebral infarction.
Previous studies have shown that proliferation of endogenous neural precursor cells cannot alone compensate for the damage to neurons and axons. From the perspective of neural plasticity, we observed the effects of functional electrical stimulation treatment on endogenous neural precursor cell proliferation and express...
25,206,808
[ -0.0155043, 0.2039421, -0.3227086, -0.1561482, 0.211505, -0.5648516, -0.06154899, -0.09933368, 0.0269016, 0.1493184, -0.1994211, 0.1912861, -0.324493, -0.271244, -0.07975698, -0.2542052, -0.1656585, -0.09356247, -0.5565674, 0.1827578, -0.1582107, -0.1222228, -0.008544914,...
Atorvastatin protects against cerebral ischemia/reperfusion injury through anti-inflammatory and antioxidant effects.
In addition to its lipid-lowering effect, atorvastatin exerts anti-inflammatory and antioxidant effects as well. In this study, we hypothesized that atorvastatin could protect against cerebral ischemia/reperfusion injury. The middle cerebral artery ischemia/reperfusion model was established, and atorvastatin, 6.5 mg/kg...
25,206,811
[ 0.004153025, 0.7711311, 0.09394622, -0.253234, 0.1366989, -0.02788911, -0.1365291, 0.01075719, 0.01043427, 0.007180729, 0.1167373, 0.2455785, -0.06622162, -0.1728594, -0.008840729, 0.1666727, -0.421544, 0.1941233, -0.009211235, 0.4419735, -0.2774367, 0.07697952, -0.179004...
The Olig family affects central nervous system development and disease.
Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous sy...
25,206,819
[ -0.03638784, -0.2200882, 0.05150514, -0.1331698, -0.08539736, -0.09137858, 0.007629773, -0.01833563, -0.1532429, 0.2283444, -0.02882719, 0.2104404, -0.03829916, 0.2079515, -0.3990192, -0.2171373, -0.1866763, 0.2182851, -0.1477475, -0.0555012, 0.04974251, 0.3013803, -0.120...
Traffic lights for axon growth: proteoglycans and their neuronal receptors.
Axon growth is a central event in the development and post-injury plasticity of the nervous system. Growing axons encounter a wide variety of environmental instructions. Much like traffic lights in controlling the migrating axons, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPGs) often...
25,206,823
[ 0.2711441, -0.09806345, 0.08103435, -0.1397536, -0.08612842, -0.2378146, -0.1781524, 0.06808395, -0.1610677, 0.2969198, 0.01514502, 0.03547312, -0.01810906, -0.1535291, -0.2890111, 0.1126834, -0.2506765, 0.1807596, 0.1487217, -0.2444149, 0.157501, 0.3679703, 0.04730012, ...
The Pael-R gene does not mediate the changes in rotenone-induced Parkinson's disease model cells.
In this study, we established cell models for Parkinson's disease using rotenone. An RNA interference vector targeting Parkin-associated endothelin receptor-like receptor (Pael-R) was transfected into the model cells. The results of reverse-transcription polymerase chain reaction and western blot analysis showed that P...
25,206,827
[ 0.02114475, -0.1946501, 0.1740125, 0.03514023, 0.1163194, 0.04721391, 0.1909389, 0.05824777, -0.02508995, 0.2090531, 0.1848965, 0.5189392, -0.1154815, 0.05287965, -0.2418537, 0.1718173, -0.5277742, 0.3373243, 0.1490268, 0.07231418, -0.01080372, 0.2417699, 0.0110635, -0....
Shuganjieyu capsule increases neurotrophic factor expression in a rat model of depression.
Shuganjieyu capsule has been approved for clinical treatment by the State Food and Drug Ad-ministration of China since 2008. In the clinic, Shuganjieyu capsule is often used to treat mild to moderate depression. In the rat model of depression established in this study, Shuganjieyu capsule was administered intragastrica...
25,206,843
[ -0.1442418, 0.0205587, 0.242016, -0.2623938, 0.2648508, -0.1075481, -0.08339112, -0.05397241, -0.04983992, 0.05707001, -0.1128145, 0.02526804, 0.05639657, -0.07298283, 0.03114138, -0.02067683, -0.03594198, 0.2438726, -0.01967387, 0.2434883, 0.1563602, 0.1006471, -0.075921...
Increased expression of Notch1 in temporal lobe epilepsy: animal models and clinical evidence.
Temporal lobe epilepsy is associated with astrogliosis. Notch1 signaling can induce astrogliosis in glioma. However, it remains unknown whether Notch1 signaling is involved in the pathogenesis of epilepsy. This study investigated the presence of Notch1, hairy and enhancer of split-1, and glial fibrillary acidic protein...
25,206,850
[ 0.279135, 0.05815395, -0.2368878, -0.3122788, 0.1471812, -0.3612743, -0.243729, -0.3870514, 0.02965144, 0.1528362, -0.1431407, 0.2664416, -0.2881911, -0.04399685, 0.2252871, 0.3319323, -0.3005601, 0.189047, -0.1898587, -0.1502465, -0.07448442, 0.300945, -0.07275342, 0.1...
Mechanisms of secondary degeneration after partial optic nerve transection.
Secondary degeneration occurs commonly in the central nervous system after traumatic injuries and following acute and chronic diseases, including glaucoma. A constellation of mechanisms have been shown to be associated with secondary degeneration including apoptosis, necrosis, autophagy, oxidative stress, excitotoxicit...
25,206,855
[ -0.3267471, -0.2691462, 0.08637628, 0.1911672, -0.05375257, -0.3931178, 0.1219451, 0.04465506, 0.103118, -0.01968923, -0.04913336, 0.005666971, -0.1072676, 0.09206127, 0.1054998, -0.2284578, -0.7159777, 0.2904923, 0.00215635, -0.04055628, -0.119519, 0.3463655, -0.09924243...
Sciatic nerve repair using adhesive bonding and a modified conduit.
When repairing nerves with adhesives, most researchers place glue directly on the nerve stumps, but this method does not fix the nerve ends well and allows glue to easily invade the nerve ends. In this study, we established a rat model of completely transected sciatic nerve injury and repaired it using a modified 1 cm-...
25,206,861
[ 0.03344997, 0.2888923, 0.0507728, -0.1815616, -0.2969082, -0.3763706, -0.06179626, -0.009011174, 0.1173637, 0.1545654, 0.01613952, 0.08725032, 0.0894689, -0.1543262, -0.3071989, 0.0355892, -0.6189916, -0.0710113, -0.1378145, 0.1577585, 0.08932164, 0.08838771, 0.2806251, ...
Effect of dexamethasone on intelligence and hearing in preterm infants: a meta-analysis.
A meta-analysis of published randomized controlled trials investigating the long-term effect of dexamethasone on the nervous system of preterm infants. Online literature retrieval was conducted using The Cochrane Library (from January 1993 to June 2013), EMBASE (from January 1980 to June 2013), MEDLINE (from January 19...
25,206,867
[ -0.07676325, -0.02578922, -0.02213335, 0.0326583, 0.27122, -0.1834734, -0.2378891, 0.1269861, 0.05987883, -0.1851441, 0.1532891, 0.2046802, -0.04472783, -0.1188131, -0.1737554, -0.03933562, -0.1967124, 0.1467079, -0.2748962, 0.02798977, 0.1208883, 0.1669475, -0.09391745, ...
Acrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injury.
IN THE HOURS TO WEEKS FOLLOWING TRAUMATIC SPINAL CORD INJURIES (SCI), BIOCHEMICAL PROCESSES ARE INITIATED THAT FURTHER DAMAGE THE TISSUE WITHIN AND SURROUNDING THE INITIAL INJURY SITE: a process termed secondary injury. Acrolein, a highly reactive unsaturated aldehyde, has been shown to play a major role in the seconda...
25,206,871
[ -0.004374392, -0.1268289, 0.1202407, -0.1854943, -0.1344896, 0.02802079, -0.2356922, 0.09056451, 0.2381526, -0.01998434, 0.01685364, -0.1250716, 0.1182846, -0.2260112, -0.08977286, -0.09600566, -0.5177007, 0.09211414, -0.06558746, 0.1926187, -0.4647636, 0.2474044, -0.1185...
Virtual reality interface devices in the reorganization of neural networks in the brain of patients with neurological diseases.
Two key characteristics of all virtual reality applications are interaction and immersion. Systemic interaction is achieved through a variety of multisensory channels (hearing, sight, touch, and smell), permitting the user to interact with the virtual world in real time. Immersion is the degree to which a person can fe...
25,206,907
[ -0.4281094, -0.06691754, 0.1279738, -0.05207558, 0.1791945, -0.3090661, -0.2253051, -0.1332133, 0.01461212, -0.4000307, 0.01775361, -0.1410362, -0.1651151, -0.491593, -0.378457, -0.3825423, -0.3128799, 0.3961069, -0.6660426, -0.04335469, -0.2640632, 0.3713922, -0.1074594,...
Chrysophanol attenuates lead exposure-induced injury to hippocampal neurons in neonatal mice.
Previous studies have shown that chrysophanol protects against learning and memory impairments in lead-exposed adult mice. In the present study, we investigated whether chrysophanol can alleviate learning and memory dysfunction and hippocampal neuronal injury in lead-exposed neonatal mice. At the end of lactation, chry...
25,206,913
[ -0.1460449, 0.04451116, -0.1665223, 0.1518168, 0.1568211, -0.1207344, -0.2014139, -0.3300033, -0.1448444, 0.3983506, 0.3054407, 0.5084823, 0.1185883, 0.05517982, 0.07452042, 0.1783828, -0.3729501, 0.2919768, 0.2756267, 0.4253101, -0.1493088, 0.4069751, -0.08447406, -0.0...
Within-session dynamics of theta-gamma coupling and high-frequency oscillations during spatial alternation in rat hippocampal area CA1.
Theta-gamma coupling in the hippocampus is thought to be involved in cognitive processes. A large body of research establishes that the hippocampus plays a crucial role in the organization and maintenance of episodic memory, and that sharp-wave ripples (SWR) contribute to memory consolidation processes. Here, we invest...
25,206,930
[ 0.1531851, 0.03199939, -0.464313, -0.1586224, 0.1006773, -0.5244531, -0.1836778, -0.3584529, 0.07526565, 0.190946, 0.1408143, -0.1831277, -0.1220022, -0.1099734, -0.3290231, -0.1894121, -0.2547227, 0.1581295, 0.1793685, -0.1942452, -0.03021904, 0.1249471, 0.1634855, -0....
Deployment-related mental health support: comparative analysis of NATO and allied ISAF partners.
For years there has been a tremendous gap in our understanding of the mental health effects of deployment and the efforts by military forces at trying to minimize or mitigate these. Many military forces have recently systematized the mental support that is provided to support operational deployments. However, the ratio...
25,206,953
[ -0.2163698, 0.209437, 0.05730189, -0.1165323, 0.05904437, -0.01441754, 0.09943608, -0.245464, -0.07090788, 0.01790049, 0.01449115, -0.2830379, 0.09151489, -0.1094241, -0.272508, -0.2384617, -0.297537, 0.07534868, -0.1878736, 0.138911, -0.06629886, 0.28846, -0.04673881, ...
Transjugular liver biopsy: results of 97 patients.
To evaluate the feasibility and efficacy of transjugular liver biopsy in patients with contraindicated percutaneous biopsy. Between June 2005 and April 2010, 97 patients who were admitted for transjugular liver biopsy were enrolled in this retrospective study. All liver biopsies were obtained using an 18 gauge Quick-Co...
25,206,981
[ -0.01220497, 0.3644519, -0.2907411, -0.1666001, -0.02261915, -0.1682659, -0.3754206, 0.0811836, -0.1600066, 0.220136, 0.2256875, 0.1202883, 0.060776, 0.1054612, -0.3036233, -0.3903614, -0.1182137, 0.2014738, 0.07442711, -0.3207217, 0.2240134, 0.1415412, -0.1380567, 0.26...
The role of insulin-like growth factor 1 in the development of benign and malignant thyroid nodules.
This study aims to investigate the role of IGF-1 in the development of nodular thyroid disease. A total number of 100 consecutive patients operated for nodular thyroid disease in our institution were included in this prospective study. In addition to classical pathological examinations, nodules and extranodular healthy...
25,206,982
[ -0.06065332, -0.2173394, -0.1305116, -0.2365116, 0.02245286, -0.3836063, -0.1020216, 0.1936395, 0.03064679, 0.2590697, 0.09059864, -0.08150955, 0.126527, -0.3889734, -0.2437416, -0.4436952, -0.04959662, 0.1157702, -0.229734, 0.01293634, 0.380812, 0.001359533, -0.1464032, ...
Comparative and Mixture Effect of Cynodon Dactylon, ElectroMagnetic Field and Insulin on Diabetic Mouse.
New investigations are in progress to find some alternative treatments for diabetes mellitus. Herbs are some of the interesting medications in this regard. Cynodon dactylon (C.d) is a potential plant to be considered as a new medication. On the other hand, the effect of the Electromagnetic Field (EMF) on bio organisms ...
25,207,031
[ -0.1387045, 0.08441515, -0.2385373, 0.3008119, 0.03202664, 0.1502104, -0.059011, 0.2998521, 0.1607733, -0.0284308, -0.01463001, 0.2424345, -0.07224824, -0.02141184, -0.4489142, -0.4333466, -0.4085965, -0.005094413, -0.07242914, 0.4520977, 0.05734728, -0.00184457, 0.057995...
Classification and localization of the adductor hiatus: a cadaver study.
To determine not only the vertical but also horizontal localization of the adductor hiatus (AH) and classify its shape and structure macroscopically. Forty lower extremities were dissected to expose the AH. Its shape and structure were macroscopically noted, and the AH was classified into four types. For determining th...
25,207,041
[ -0.01268713, 0.2811138, 0.1850726, 0.1122678, 0.3166515, -0.202374, -0.08096814, 0.457409, -0.1453913, 0.08255278, 0.1109937, -0.1823911, -0.1796713, -0.3767855, -0.5078555, -0.1101857, -0.2990769, 0.3788535, 0.02432753, -0.3218673, 0.2666157, 0.09597994, -0.129887, -0....
Autoimmune pancreatitis and treatment approaches with case reports.
In this study, we aimed to review retrospectively the data of 10 patient who were treated and followed-up in our clinic and to review the current approaches in the diagnosis and treatment of autoimmune pancreatitis (AIP). We reviewed 10 patients retrospectively who were operated on and had the diagnosis of AIP histopat...
25,207,048
[ -0.09791125, -0.473126, 0.219146, -0.2577399, -0.07101095, -0.3168858, 0.1745777, 0.1792091, 0.07953925, 0.301601, 0.189247, -0.05624183, -0.05027292, -0.1482992, -0.2506502, -0.1069399, -0.1377219, -0.06879855, -0.03257484, 0.1214642, -0.1932229, 0.1646743, -0.2445308, ...
The rate of seasonal influenza vaccination in diabetic children, the effect of recommendation and the factors influencing the acceptance of recommendation: an interventional study.
To investigate the vaccination rate of influenza in diabetic children and the effect of recommendation and other factors on vaccination rate. On July 2011, 144 diabetic children and their families were informed about and were recommended to receive the influenza vaccine every year, in September. On December 2011, paren...
25,207,049
[ -0.09632263, -0.1429804, -0.03113658, 0.06484865, 0.1904218, -0.4165882, -0.09997547, -0.09891632, -0.1589106, -0.1023273, 0.04504006, 0.03578502, 0.04129054, -0.09619915, -0.1665244, -0.01890466, 0.3332959, 0.1794614, -0.02682801, -0.1005033, 0.2934823, -0.2145702, -0.06...