title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Beyond my wildest expectations. | With support from my parents, I fulfilled their and my expectations of graduating from college and becoming a scientist. My scientific career has focused on two organisms, Bacillus subtilis and Agrobacterium tumefaciens, and two experimental systems, aromatic amino acid synthesis and DNA transfer in bacteria and plants... | 25,208,299 | [
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Preoperative imaging of sensorineural hearing loss in pediatric candidates for cochlear implantation. | Cochlear implantation is the only U.S. Food and Drug Administration-approved treatment for children with marked bilateral sensorineural hearing loss. It provides auditory benefits that range from simple sound detection to substantial word understanding. Improved hearing through cochlear implantation has been demonstrat... | 25,208,295 | [
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Sex difference for urologic malignancy risk in uremic patients after kidney transplantation: a population-based study. | High urologic malignancy incidence has been reported in end-stage renal disease (ESRD) patients, especially of female sex. This study was undertaken to evaluate whether female recipients still carry an aggravated risk of this malignancy after kidney transplantation (KT). The claims data from the Bureau of National Heal... | 25,208,323 | [
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visPIG--a web tool for producing multi-region, multi-track, multi-scale plots of genetic data. | We present VISual Plotting Interface for Genetics (visPIG; http://vispig.icr.ac.uk), a web application to produce multi-track, multi-scale, multi-region plots of genetic data. visPIG has been designed to allow users not well versed with mathematical software packages and/or programming languages such as R, Matlab®, Pyt... | 25,208,325 | [
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Effect of TiO2 nanoparticles and UV radiation on extracellular enzyme activity of intact heterotrophic biofilms. | When introduced into the aquatic environment, TiO2 NP are likely to settle from the water column, which results in increased exposure of benthic communities. Here, we show that the activity of two extracellular enzymes of intact heterotrophic biofilms, β-glucosidase (carbon-cycling) and l-leucin aminopeptidase (nitroge... | 25,208,344 | [
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Influence of implant surface topography on bone-regenerative potential and mechanical retention in the human maxilla and mandible. | To evaluate the short- and mid-term effects of commercial pure (cp) titanium implant surface topography on osseointegration, bone-regenerative potential and mechanical retention in the human maxilla and mandible. 32 micro-implants with the same geometry but with four different surface treatments were implanted in the m... | 25,208,367 | [
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[Study on the thermal radiation polarization characteristics of ice]. | As an important parameter of the global energy balance, climate, hydrological and ecological model, ice directly affects the energy balance of the earth-atmosphere system, weather and climate. It is of great significance to use the thermal infrared polarization technology to study ice thermal radiation. For the ice mon... | 25,208,376 | [
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[Preparation and up-conversion luminescence properties of Yb3+/Tm3+ co-doped Sb2O4 powder]. | The Sb2O4:Yb3+, Tm3+ up-conversion luminescence powder with excellent physical, chemical stability and relative low phonon energy was synthesized by the high temperature solid-state reaction and its up-conversion luminescence property was investigated. Under the 980 nm excitation, infrared and blue up-conversion emissi... | 25,208,379 | [
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[Resonance Rayleigh scattering determination of trace ozone based on the cationic surfactant association particles]. | In the presence of pH 4.0 HAC-NaAC buffer solution, using H3BO3-KI (BKI) as absorption solution, O3 oxidized KI to produce I2, and it reacted with excess I- to form I3- that combined with the cationic surfactant (CS) such as cetylpyridinium chloride (CPCl), tetradecyl pyridinium bromide (TPB), cetyl trimethyl ammonium ... | 25,208,401 | [
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[A quickly atmospheric correction method for HJ-1 CCD with deep blue algorithm]. | In the present, for the characteristic of HJ-1 CCD camera, after receiving aerosol optical depth (AOD) from deep blue algorithm which was developed by Hsu et al. assisted by MODerate-resolution imaging spectroradiometer (MODIS) surface reflectance database, bidirectional reflectance distribution function (BRDF) correct... | 25,208,402 | [
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[Modification on the interaction of glipizide with bovine serum albumin by molecular spectroscopy]. | In the Tris-HCl buffer solution with pH was 7.40, the interaction between glipizide (Gli) and bovine serum albumin (BSA) was investigated by classical fluorescence spectroscopy with the change of protein as investigation object and elastic scattering fluorescence spectrometry with the change of drugs as investigation o... | 25,208,408 | [
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[Preliminary study of atomic emission spectrometry of Ti (H) plasma produced by vacuum arc ion source]. | In order to study the discharge process of vacuum arc ion source, make a detail description of the discharge plasma, and lay the foundation for further research on ion source, atomic emission spectrometry was used to diagnose the parameters of plasma produced by vaccum arc ion source. In the present paper, two kinds of... | 25,208,416 | [
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[Spectroscopic analysis of the decay resistance of wood treated with extracts from the xylem of Cinnamomum Camphora with XRD and FTIR approaches]. | Four kinds of extracts from the xylem of C. Camphora, ACQ and camphor were selected to make wood preservatives for laboratory toxicity test of wood preservatives for decay fungus. The results showed that the treated blocks with 4% ACQ and 10% methanol extracts could meet the demand of degree I of preservation and showe... | 25,208,421 | [
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Clinical characteristics and healthcare utilization of patients with multicentric Castleman disease. | Multicentric Castleman disease (MCD) is a rare lymphoproliferative disease. Little is known about how patient clinical features and healthcare utilization varies by human immunodeficiency virus (HIV) status and disease subtype. Data of MCD patients identified between 2000 and 2009 were collected from medical records at... | 25,208,471 | [
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Evaluation of renal graft function based on standard mathematical formulas. | Creatinine is a standard marker for estimation of the transplanted kidney function. Concentration values are used in mathematical equations for GFR (glomerular filtration rate) calculation, with MDRD (modification diet in renal disease) being most commonly used. Cystatin C is an alternative marker for changes in glomer... | 25,208,483 | [
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Working memory recall precision is a more sensitive index than span. | Delayed adjustment tasks have recently been developed to examine working memory (WM) precision, that is, the resolution with which items maintained in memory are recalled. However, despite their emerging use in experimental studies of healthy people, evaluation of patient populations is sparse. We first investigated th... | 25,208,525 | [
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Cardiovascular risk stratification in diabetic patients following stress single-photon emission-computed tomography myocardial perfusion imaging: the impact of achieved exercise level. | Previous studies have demonstrated that diabetic patients undergoing exercise stress single-photon emission-computed tomography (SPECT) myocardial perfusion imaging (MPI) have significantly lower cardiac events when compared to the diabetic patients undergoing pharmacologic stress SPECT MPI across all perfusion categor... | 25,208,530 | [
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Effects of dark chocolate consumption on the prothrombotic response to acute psychosocial stress in healthy men. | Flavanoid-rich dark chocolate consumption benefits cardiovascular health, but underlying mechanisms are elusive. We investigated the acute effect of dark chocolate on the reactivity of prothrombotic measures to psychosocial stress. Healthy men aged 20-50 years (mean ± SD: 35.7 ± 8.8) were assigned to a single serving o... | 25,208,561 | [
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Identification of a novel cytochrome P450 gene, CYP321E1 from the diamondback moth, Plutella xylostella (L.) and RNA interference to evaluate its role in chlorantraniliprole resistance. | Insect cytochrome P450 monooxygenases (P450s) play an important role in catalysis of many reactions leading to insecticides resistance. Our previous studies on transcriptome analysis of chlorantraniliprole-resistant development in the diamondback moth, Plutella xylostella revealed that up-regulation of cytochrome P450s... | 25,208,571 | [
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Approaches to improve quality of care (QoC) for women and newborns: conclusions, evidence gaps and research priorities. | This series of papers focuses on a quality of care framework for maternal health, and systematically reviews the evidence of interventions aimed at improving care at the community-, district- and factility-levels. While the systematic reviews highlight the effectiveness of specific quality improvement efforts on matern... | 25,208,572 | [
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Tibial hydatidosis: a case report. | Hydatidosis is a tapeworm infection caused by the larval stage of Echinococcus species. The organs most frequently affected are the liver and the lungs. Primary involvement of the skeleton is rare. The location of hydatid cysts in the tibia is seldom described in the medical literature, and its diagnosis is challenging... | 25,208,573 | [
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Comparison of measurements of mandible growth using cone beam computed tomography and its synthesized cephalograms. | The current study aimed to compare the measurements of the mandible morphology using 3D cone beam computed tomography (CBCT) images with those using 2D CBCT-synthesized cephalograms; to quantify errors in measurements based on 2D synthesized cephalograms; and to clarify the effects such errors have on the description o... | 25,208,578 | [
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'I didn't know why you had to wait': an evaluation of NHS infant-feeding workshops amongst women living in areas of high deprivation. | Inappropriate maternal and infant-feeding practices are known to have a major impact on morbidity in infancy, childhood and later life. Ring-fenced funding over 3 years from the Scottish Government to the National Health Service (NHS) in Scotland has allowed the development of a range of nutrition interventions for wom... | 25,208,593 | [
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Oral Chinese herbal medicine combined with pharmacotherapy for psoriasis vulgaris: a systematic review. | Clinically, oral Chinese herbal medicine (CHM) is widely used in the treatment of psoriasis. This review evaluates the effects of oral CHM in combination with pharmacotherapy for psoriasis vulgaris. The Cochrane Library, PubMed, Embase, CINAHL, CNKI, and CQVIP were searched from their inceptions to November 2012. Rando... | 25,208,594 | [
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Long-acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B-LONG study. | In the phase 3 B-LONG (Recombinant Factor IX Fc Fusion Protein [rFIXFc] in Subjects With Haemophilia B) study, rFIXFc demonstrated a prolonged half-life compared with recombinant factor IX (rFIX), and safety and efficacy for prophylaxis and treatment of bleeding in subjects with moderately-severe to severe haemophilia ... | 25,208,598 | [
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Chemo-mechanics of salt damage in stone. | Many porous materials are damaged by pressure exerted by salt crystals growing in their pores. This is a serious issue in conservation science, geomorphology, geotechnical engineering and concrete materials science. In all cases, a central question is whether crystallization pressure will cause damage. Here we present ... | 25,208,600 | [
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Half sandwich ruthenium(II) hydrides: hydrogenation of terminal, internal, cyclic and functionalized olefins. | Bis(1,2,3-triazolylidene) silver(I) complex 1a was reacted with [RuCl2(p-cymene)]2 to give the ruthenium complex [PhCH2N2(NMe)C2(C6H4CF3)]RuCl2(p-cymene) (2a) as major product in addition to the minor C(sp(2))-H activated product [PhCH2N2(NMe)C2(C6H3CF3)]RuCl(p-cymene) (2a'). Similar ruthenium complexes 2b, 2c, 2d and ... | 25,208,607 | [
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Graphene oxide hydration and solvation: an in situ neutron reflectivity study. | Graphene oxide membranes were recently suggested for applications in separation of ethanol from water using a vapor permeation method. Using isotope contrast, neutron reflectivity was applied to evaluate the amounts of solvents intercalated into a membrane from pure and binary vapors and to evaluate the selectivity of ... | 25,208,613 | [
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Significance of early prostate-specific antigen values after salvage radiotherapy in recurrent prostate cancer patients treated with surgery. | To assess the use of post-salvage radiotherapy prostate-specific antigen for early prediction of biochemical failure or clinical recurrence after salvage radiotherapy in recurrent prostate cancer patients after prostatectomy. From 2000 to 2011, 164 patients were treated with salvage radiotherapy alone for recurrent pro... | 25,208,624 | [
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Biomechanics principle of elbow joint for transhumeral prostheses: comparison of normal hand, body-powered, myoelectric & air splint prostheses. | Understanding of kinematics force applied at the elbow is important in many fields, including biomechanics, biomedical engineering and rehabilitation. This paper provides a comparison of a mathematical model of elbow joint using three different types of prosthetics for transhumeral user, and characterizes the forces re... | 25,208,636 | [
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Effect of metal doping, doped structure, and annealing under argon on the properties of 30 nm thick ultrathin hematite photoanodes. | The doping of the whole hematite layer with W (9.4%) and the additional doping of the bottom half of the W-doped hematite layer with Sn (8.6%), and the subsequent annealing under argon at 600 °C give rise to large increases in the Fe(2+) concentration (by >∼200 times), carrier density (Cd, by ∼48 times) and current ... | 25,208,648 | [
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The effect of tungstate nanoparticles on reactive oxygen species and cytotoxicity in raw 264.7 mouse monocyte macrophage cells. | Due to their unique size, surface area, and chemical characteristics, nanoparticles' use in consumer products has increased. However, the toxicity of nanoparticle (NP) exposure during the manufacturing process has not been fully assessed. Tungstate NP are used in numerous products, including but not limited to scintill... | 25,208,664 | [
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Monitoring of hematological and hemostatic parameters in neurocritical care patients. | Anemia and bleeding are paramount concerns in neurocritical care and often relate to the severity of intracranial hemorrhage. Anemia is generally associated with worse outcomes, and efforts to minimize anemia through reduced volume of blood sampled are encouraged. Point-of-care-testing reliably detects the use of non-s... | 25,208,669 | [
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Multimodality monitoring: informatics, integration data display and analysis. | The goal of multimodality neuromonitoring is to provide continuous, real-time assessment of brain physiology to prevent, detect, and attenuate secondary brain injury. Clinical informatics deals with biomedical data, information, and knowledge including their acquisition, storage, retrieval, and optimal use for clinical... | 25,208,675 | [
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High-efficiency AgInS(2)-modified ZnO nanotube array photoelectrodes for all-solid-state hybrid solar cells. | Highly ordered AgInS2-modified ZnO nanoarrays were fabricated via a low-cost hydrothermal chemical method, and their application as all-solid-state solar cells was also tested. A sensitizer and a buffer layer were developed around the surface of ZnO nanotubes in the preparation process, and this method is easily be man... | 25,208,689 | [
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Role of macropore flow in the transport of Escherichia coli cells in undisturbed cores of a brown leached soil. | The objective of this work was to evaluate the transport of Escherichia coli cells in undisturbed cores of a brown leached soil collected at La Côte St André (France). Two undisturbed soil cores subjected to repeated injections of bacterial cells and/or bromide tracer were used to investigate the effect of soil hydrody... | 25,208,699 | [
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Spatial and temporal trend of groundwater contamination from terbuthylazine and desethyl-terbuthylazine in the Lombardy Region (Italy). | In the last few years, several monitoring programs were established as an effect of the EU Directives which included requirements for monitoring the quality of water resources (drinking water, groundwater and surface water). Plant Protection Products (PPPs) are an obvious target for monitoring activities, since they ar... | 25,208,701 | [
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Metal release from stainless steel powders and massive sheets--comparison and implication for risk assessment of alloys. | Industries that place metal and alloy products on the market are required to demonstrate that they are safe for all intended uses, and that any risks to humans, animals or the environment are adequately controlled. This requires reliable and robust in vitro test procedures. The aim of this study is to compare the relea... | 25,208,703 | [
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Person-specific theory of mind in medial pFC. | Although research on theory of mind has strongly implicated the dorsomedial pFC (incuding medial BA 8 and BA 9), the unique contributions of medial pFC (MPFC; corresponding to medial BA 10) to mentalizing remain uncertain. The extant literature has considered the possibility that these regions may be specialized for se... | 25,208,740 | [
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Natural occurrence of mycotoxins in forage maize during crop growth in Japan: case study. | We investigated concentrations of mycotoxins during the growth of four cultivars of forage maize (Zea mays L.) in Nasushiobara, Tochigi prefecture, and their distribution in ears of maize grown in Morioka, Iwate prefecture, Japan. In experiment 1, we measured concentrations of naturally occurring fumonisin, nivalenol, ... | 25,208,749 | [
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Generation, expansion, and differentiation of cardiovascular progenitor cells from human pluripotent stem cells. | Cardiovascular progenitor cells (CVPCs) derived from human embryonic stem cells and human induced pluripotent stem cells represent an invaluable potential source for the study of early embryonic cardiovascular development and stem cell-based therapies for congenital and acquired heart diseases. To fully realize their v... | 25,208,753 | [
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HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea. | The aim of this study was to compare the efficacy and safety of once-weekly albiglutide with once-daily insulin glargine (A21Gly,B31Arg,B32Arg human insulin) in patients with type 2 diabetes inadequately controlled on metformin with or without sulfonylurea. This was a randomised, open-label, multicentre (n = 222), para... | 25,208,756 | [
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Adhesion molecules and chemokines; relation to anthropometric, body composition, biochemical and dietary variables. | Among the inflammatory mediators involved in the pathogenesis of obesity, the cell adhesion molecules P-selectin, E-selectin, VCAM-1, ICAM-1 and the chemokine MCP-1 stand out. They play a crucial role in adherence of cells to endothelial surfaces, in the integrity of the vascular wall and can be modulated by body compo... | 25,208,773 | [
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Association between childhood obesity and oral hygiene status. | The purpose of this study was to evaluate the oral hygiene status in pediatric obese patients. A cross-sectional study was conducted from 2011 to 2012, which evaluated 180 Brazilian pediatric patients, 6-14 years old, girls and boys, recruited according to two Body Mass Index (BMI) categories: obese and non-obese (heal... | 25,208,776 | [
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Impact of parenteral nutrition standardization on costs and quality in adult patients. | Parenteral nutrition (PN) is a costly therapy that can also be associated with serious complications. Therefore, efforts are focusing on reducing rate of complications, and costs related to PN. The aim was to analyze the effect of the implementation of PN standardization on costs and quality criteria. Secondary aim was... | 25,208,790 | [
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[Bone mineral density, dietary calcium and risk factor for presumptive osteoporosis in Ecuadorian aged women]. | Osteoporosis is a cause for pathological fractures and loss of autonomy and validism in the postmenopausal woman. Identification of risk factors might serve for preventing the appearance of this co-morbidity. To determine the association between loss of bone mineral density (BMD) and selected demographic, clinical and ... | 25,208,793 | [
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State of malnutrition in hospitals of Ecuador. | Hospital malnutrition is a global health problem affecting 30-50% of hospitalized patients. There are no estimates of the size of this problem in Ecuadorian hospitals. Hospital malnutrition might influence the quality of medical assistance provided to hospitalized populations. To estimate the current frequency of malnu... | 25,208,799 | [
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Dietary restraint and subjective well-being in university students in Chile. | To characterize university students typologies according to chronic food restriction, satisfaction with life and food consumption. A questionnaire was applied on a non-probability sample of 369 male and female students from five Chilean universities. The questionnaire included: Revised Restraint Scale (RRS), Satisfacti... | 25,208,802 | [
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Risk and impact of tuberculosis in patients with chronic myeloid leukemia: a nationwide population-based study in Taiwan. | The relationship between chronic myeloid leukemia (CML) and tuberculosis (TB) has not been determined. We conducted a national survey including 1,082 CML patients identified from the Taiwan National Health Insurance database covering a period between 1998 and 2011; the matched non-exposed cohort included 10,820 subject... | 25,208,807 | [
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Is there any effect of lower extremity deep vein thrombosis which proven by Doppler ultrasonography on cancer recurrence in patients with stage III colon cancer? A study of the Turkish Descriptive Oncological Researches Group. | This study aimed to determine the predictive value of lower extremity deep vein thrombosis (LE-DVT) on first cancer recurrence in patients with stage III colon cancer. A total of 113 eligible patients with stage III colon cancer were divided into two groups according to whether they had LE-DVT. LE-DVT was detected in 2... | 25,208,817 | [
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Synthesis of enantiomerically enriched indolines and tetrahydroisoquinolines from (S)-amino acid-derived chiral carbocations: an easy access to (3S,4R)-demethoxy-3-isopropyl diclofensine. | Enantiomerically enriched indolines and tetrahydroisoquinolines were synthesized within 5 min to 2 h in high yields from easily accessible (S)-amino acid derived chiral carbocations. The diastereoselective Friedel-Crafts reaction is promoted by a Lewis acid (AlCl3) offering trans-diastereoselectivity. The rate of the r... | 25,208,820 | [
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A ratiometric fluorescent probe based on ESIPT and AIE processes for alkaline phosphatase activity assay and visualization in living cells. | Alkaline phosphatase (ALP) activity is regarded as an important biomarker in medical diagnosis. A ratiometric fluorescent probe is developed based on a phosphorylated chalcone derivative for ALP activity assay and visualization in living cells. The probe is soluble in water and emits greenish-yellow in aqueous buffers.... | 25,208,827 | [
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[Textual research on Costus root (Aucklandia lappa Decne) in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica)]. | Aucklandia lappa Decne was first recorded in the Sheng nong ben cao jing (Shennong's Classic of Materia Medica). Through the textual research of herbal literature, it was found that the costus root in the Sheng nong ben cao jing perhaps was not the plant of Aucklandia lappa Decne of Compositae, but the eaglewood or Lig... | 25,208,833 | [
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[Discussion on the causation of fake crude medicinal materials in the Ming Dynasty]. | In the Ming Dynasty, the phenomenon of fake crude medicinal materials is very common. Its fundamental reasons are the development of commodity economy and the tense relationship between supply and demand, reflecting in the stimulation of infinite demand of crude drugs initiated by the government and folk aspects, and t... | 25,208,834 | [
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Survey of delivery room resuscitation practices at tertiary perinatal centers in Japan. | The aim of this study was to determine the current neonatal resuscitation practices for term infants in Japan, immediately before the 2010 publication of the international neonatal resuscitation consensus. In January 2010, a 26-question survey was mailed to neonatal department directors. A total of 287 neonatal departm... | 25,208,847 | [
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Acupuncture for neurogenic bladder due to spinal cord injury: a systematic review protocol. | Neurogenic bladder is one of the most common complications following spinal cord injury (SCI). In China, acupuncture therapy is a common treatment for neurogenic bladder due to SCI, but its effects and safety remain uncertain. A protocol is described for a systematic review to investigate the beneficial effects and saf... | 25,208,851 | [
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Gaps in receipt of regular eye examinations among medicare beneficiaries diagnosed with diabetes or chronic eye diseases. | To examine a wide range of factors associated with regular eye examination receipt among elderly individuals diagnosed with glaucoma, age-related macular degeneration, or diabetes mellitus (DM). Retrospective analysis of Medicare claims linked to survey data from the Health and Retirement Study (HRS). The sample consis... | 25,208,856 | [
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Stereotactic radiotherapy for neovascular age-related macular degeneration: year 2 results of the INTREPID study. | To determine the safety and efficacy of low-voltage, external-beam, stereotactic radiotherapy (SRT) for patients with neovascular age-related macular degeneration (AMD). Randomized, double-masked, sham-controlled, multicenter, clinical trial. A total of 230 participants with neovascular AMD who received ≥ 3 ranibizumab... | 25,208,859 | [
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Qualification of a noninvasive magnetic resonance imaging biomarker to assess tumor oxygenation. | Although hypoxia has been long recognized as a crucial factor impairing tumor response in many therapeutic schemes, atraumatic and reliable methods of individually quantifying tumor oxygenation are still lacking in day-to-day clinical practice. The aim of this work was to investigate the potentially quantitative proper... | 25,208,881 | [
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Impermeable barrier films and protective coatings based on reduced graphene oxide. | Flexible barrier films preventing permeation of gases and moistures are important for many industries ranging from food to medical and from chemical to electronic. From this perspective, graphene has recently attracted particular interest because its defect-free monolayers are impermeable to all atoms and molecules. Ho... | 25,208,890 | [
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[18F]FDG-PET/CT for the diagnosis of patients with fever of unknown origin. | The diagnosis of patients with fever of unknown origin (FUO) remains a challenging medical problem. We aimed to assess the diagnostic contribution of 18-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET)/computed tomography (CT) for the evaluation of FUO. We performed a 4-year retrospective single-center s... | 25,208,896 | [
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Prevalence of psychosis in black ethnic minorities in Britain: analysis based on three national surveys. | A considerable excess of psychosis in black ethnic minorities is apparent from clinical studies, in Britain, as in other developed economies with white majority populations. This excess is not so marked in population surveys. Equitable health service provision should be informed by the best estimates of the excess. We ... | 25,208,909 | [
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Use of silicone tracheal stoma stents for temporary tracheostomy in dogs with upper airway obstruction. | To report the use of silicone tracheal stoma stents for temporary tracheostomy in dogs with upper airway obstruction. Retrospective review of medical records for dogs in which silicone tracheal stoma stents were placed. Eighteen dogs had a silicone tracheal stoma stent placed for maintenance of a tracheostomy stoma for... | 25,208,924 | [
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Comment on: IgA nephropathy with early kidney disease is associated with increased arterial stiffness and renin-angiotensin system activity. | We read with great interest the article by Abdi-Ali et al. entitled "IgA nephropathy with early kidney disease is associated with increased arterial stiffness and renin-angiotensin system activity" in the recent issue of Journal of the Renin-Angiotensin-Aldosterone System. In a study on 10 normotensive IgA nephropathy ... | 25,208,932 | [
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... |
Appraisal of evidence base for introduction of new implants in hip and knee replacement: a systematic review of five widely used device technologies. | To determine the evidence of effectiveness and safety for introduction of five recent and ostensibly high value implantable devices in major joint replacement to illustrate the need for change and inform guidance on evidence based introduction of new implants into healthcare. Systematic review of clinical trials, compa... | 25,208,953 | [
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Guiding principles of fluid and volume therapy. | Fluid therapy is a core concept in the management of perioperative and critically ill patients for maintenance of intravascular volume and organ perfusion. Recent evidence regarding the vascular barrier and its role in terms of vascular leakage has led to a new concept for fluid administration. The choice of fluid used... | 25,208,960 | [
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0.0843149... |
Update on volume therapy in obstetrics. | Symptomatic hypotension (maternal nausea, vomiting, dizziness and dyspnoea) during spinal anaesthesia for caesarean delivery remains a prevalent clinical problem. Severe and sustained hypotension can lead to impairment of uteroplacental perfusion, foetal hypoxia, acidosis, neonatal depression and further adverse matern... | 25,208,964 | [
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0.02412... |
Scalable integration of Li5FeO4 towards robust, high-performance lithium-ion hybrid capacitors. | Lithium-ion hybrid capacitors have attracted great interest due to their high specific energy relative to conventional electrical double-layer capacitors. Nevertheless, the safety issue still remains a drawback for lithium-ion capacitors in practical operational environments because of the use of metallic lithium. Here... | 25,208,971 | [
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Genetics of opiate addiction. | Addiction to MOP-r agonists such as heroin (and also addiction to prescription opioids) has reemerged as an epidemic in the twenty first century, causing massive morbidity. Understanding the genetics contributing to susceptibility to this disease is crucial for the identification of novel therapeutic targets, and also ... | 25,209,027 | [
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Hearing and loud music exposure in 14-15 years old adolescents. | Adolescent exposure to loud music has become a social and health problem whose study demands a holistic approach. The aims of the current study are: (1) To detect early noise-induced hearing loss among adolescents and establish its relationship with their participation in musical recreational activities and (2) to dete... | 25,209,042 | [
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What has changed from 2001 to 2012 for sexual minority youth in New Zealand? | To provide an overview of the health and well-being of sexual minority high school students in New Zealand, investigate differences between sexual minority youth (SMY) and exclusively opposite-sex-attracted youth (EOSAY), and examine changes across survey waves. Nationally representative cross-sectional surveys were co... | 25,209,060 | [
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Correlation 2D-NMR experiments involving both 13C and 2H isotopes in oriented media: methodological developments and analytical applications. | Correlation 2D-NMR experiments for (13)C and (2)H isotopes turn out to be powerful methods for the assignment of the quadrupolar doublets in the (2)H NMR spectra of isotopically modified (polydeuterated or perdeuterated) or unmodified solutes in homogeneously oriented solvents, such as thermotropic systems or lyotropic... | 25,209,071 | [
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Determination of hidden hazelnut oil proteins in extra virgin olive oil by cold acetone precipitation followed by in-solution tryptic digestion and MALDI-TOF-MS analysis. | Adulteration of extra-virgin olive oil (EVOO) with hazelnut oil (HO) is an illegal practice that could have severe health consequences for consumers due to the possible exposure to hidden hazelnut allergens. Here, matrix-assisted laser-desorption/ionization (MALDI) mass spectrometry (MS) was used as a rapid and sensiti... | 25,209,075 | [
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Transition to adult life in the monogenic epilepsies. | There are many monogenic disorders associated with epilepsy that begin in childhood and persist into adult life. Each of these disorders raises specific issues for transition, in addition to common issues facing this group of patients as they move from pediatric to adult care. Such comorbidities include psychiatric and... | 25,209,079 | [
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Transition issues for children with diffuse cortical malformations, multifocal postnatal lesions, (infectious and traumatic) and Lennox-Gastaut and similar syndromes. | Patients with epilepsy may have diffuse, serious brain disorders including genetically determined, multilobar malformations, traumatic brain injury, encephalitis and meningitis, and the many causes of Lennox-Gastaut syndrome. Transition to adult care needs to consider concomitant intellectual disability, refractory epi... | 25,209,082 | [
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Preeclampsia, prematurity and cardiovascular health in adult life. | Investigations into how perinatal growth and intrauterine environment may 'programme' risk of later cardiovascular disease have been ongoing for over two decades. One of the more recent outcomes of these studies is the observation that certain pregnancy-related conditions, such as preterm birth, have an unusually large... | 25,209,092 | [
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Common opossum (Didelphis marsupialis Linnaeus, 1758): food and medicine for people in the Amazon. | In the Amazon rainforest, biodiversity is a significant resource for traditional communities, as it can be used as a relevant source of protein and it has a promising zootherapeutic potential. Studies on knowledge and ways how local peoples use the fauna are still incipient. This paper presents both the knowledge on an... | 25,209,094 | [
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Effect of preoperative P2Y12 and thrombin platelet receptor inhibition on bleeding after cardiac surgery. | Drugs that act on the platelet P2Y12 receptor are responsible for postoperative bleeding in cardiac surgery. However, protease-activated receptor (PAR) that reacts to thrombin stimulation might still be active in patients treated with P2Y12 inhibitors. Preoperative platelet function testing could possibly guide the tim... | 25,209,096 | [
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Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow. | An experimentally easy to perform method for the generation of alumina-supported Fe3O4 nanoparticles [(6±1) nm size, 0.67 wt %]and the use of this material in hydrazine-mediated heterogeneously catalyzed reductions of nitroarenes to anilines under batch and continuous-flow conditions is presented. The bench-stable, reu... | 25,209,099 | [
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Why do some physicians in Portuguese-speaking African countries work exclusively for the private sector? Findings from a mixed-methods study. | Despite the growing interest in the private health sector in low- and middle-income countries, little is known about physicians working outside the public sector. The present work adopts a mixed-methods approach to explore characteristics, working patterns, choices, and motivations of the physicians working exclusively... | 25,209,103 | [
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Obesity and related risk factors in gastric cardia adenocarcinoma. | Over recent decades, the incidence of cancers of the gastroesophageal junction, including gastric cardia tumors, has increased markedly. This is a trend that has been well documented, especially in studies from the USA and northern Europe that have also demonstrated a concomitant rise in the ratio of cardia to distal g... | 25,209,115 | [
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Prospective randomized study of chevron osteotomy versus Mitchell's osteotomy in hallux valgus. | We conducted a prospective randomized trial to compare the most popular osteotomy types of operative treatment of hallux valgus (HV) used in Norway, Mitchell's osteotomy (MO) and chevron osteotomy (CO). One hundred twenty adult female patients were prospectively randomized to treatment with either MO or CO. All operati... | 25,209,122 | [
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-0.01119931,
-0.1183667,
0.06085552,
-0.05026978,
0.02455331,
-0.20398... |
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). | Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is a rare clinical syndrome of unknown cause usually identified in children. Tonsillectomy is considered a potential treatment option for this syndrome. This is an update of a Cochrane review first published in 2010. To assess the e... | 25,209,127 | [
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0.02537885,
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0.2235102,
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Prevention and Treatment of NSAID Gastropathy. | Nonsteroidal anti-inflammatory drug (NSAID) treatment will be necessary as part of our therapeutic armamentarium for many years to come. Therefore, safe prescription is mandatory in order to prevent adverse events. In the last two decades, new strategies and new drugs have been developed to reduce NSAID-associated uppe... | 25,209,136 | [
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... |
Relationships and genetic consequences of contrasting modes of speciation among endemic species of Robinsonia (Asteraceae, Senecioneae) of the Juan Fernández Archipelago, Chile, based on AFLPs and SSRs. | This study analyses and compares the genetic signatures of anagenetic and cladogenetic speciation in six species of the genus Robinsonia (Asteraceae, Senecioneae), endemic to the Juan Fernández Islands, Chile. Population genetic structure was analyzed by amplified fragment length polymorphism (AFLP) and microsatellite ... | 25,209,139 | [
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0.3906947,
0.252149,
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Optic nerve and retinal features in uveitis associated with juvenile systemic granulomatous disease (Blau syndrome). | To determine whether patients with juvenile systemic granulomatous disease (JSGD) (Blau syndrome) and uveitis have a characteristic ocular phenotype. Clinical and imaging data were collected retrospectively from patients attending the Regional Combined Paediatric Rheumatology and Ocular Inflammatory Service, Bristol Ey... | 25,209,167 | [
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0... |
Teaching the Z-Scheme of electron transport in photosynthesis: a perspective. | This paper deals with how Govindjee taught the Z-Scheme of electron transport in oxygenic photosynthesis at Ravenshaw University, Cuttack, Odisha, India, in 2014, in a unique and highly effective fashion-using students to act as molecules, representing the entire electron transport chain from water to nicotinamide aden... | 25,209,177 | [
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0.3219449,
0.307768,
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Diagnostic value of alpha-fetoprotein-L3 and Golgi protein 73 in hepatocellular carcinomas with low AFP levels. | This study aimed to investigate the clinical values of serum alpha-fetoprotein-L3 (AFP-L3) and Golgi protein 73 (GP73) in the diagnosis of hepatocellular carcinoma (HCC) with low alpha-fetoprotein (AFP). From January 2011 to December 2013, 50 low-AFP HCC patients confirmed by the color Doppler flow imaging (CDFI) and p... | 25,209,179 | [
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0.1636492,
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0.22757,
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... |
Effects of whole-body heat on male germ cell development and sperm motility in the laboratory mouse. | This study investigated the effects of high temperatures on male germ cell development and epididymal sperm motility of laboratory mice. In Experiment 1, adult males (n=16) were exposed to whole-body heat of 37-38°C for 8h day(-1) for 3 consecutive days, whereas controls (n=4) were left at 23-24°C. In Experiment 2, adu... | 25,209,189 | [
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0.04575051,
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0.3589751,
0.5101454,
-0.2668421... |
Turkish version of the Rotator Cuff Quality of Life questionnaire in rotator cuff-impaired patients. | To date, the "Rotator Cuff Quality of Life" (RC-QOL) measure has not been translated into Turkish. The aim of this study was to perform a cross-cultural adaptation of the questionnaire and determine the reliability and reproducibility of the "Turkish version of the RC-QOL" (Tur-RC-QOL) questionnaire on Turkish-speaking... | 25,209,207 | [
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0.02051059,
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0.09945217,
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0.02170758,
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0.06939354,
0.05783356,
-0.05056837,
0.2887... |
Driving reaction times in patients with foot and ankle pathology before and after image-guided injection: pain relief without improved function. | Foot and ankle pathology is common in the driving population. Local anesthetic steroid injections are frequent ambulatory treatments. Brake reaction time (BRT) has validated importance in motor vehicle safety. There are no prior studies examining the effect of foot and ankle pathology and injection treatment on the saf... | 25,209,215 | [
-0.03783654,
0.001484439,
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0.1469655,
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0.2386012,
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0.1891682,
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0.1131742,
0.2559708,
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0.3056861,
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0.3504667,
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Non surgical treatment of Crouzon syndrome. | Crouzon syndrome is an autosomal dominant disorder with variable expressivity, characterized by skull and facial malformations. Such alterations vary from case to case. Management requires multidisciplinary approach. Two cases of two sisters affected by Crouzon syndrome are described. Treatment was performed by orthope... | 25,209,230 | [
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0.2292878,
0.2000043,
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0.3264337,
0.2579758,
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0.09118692,
-0.09875619,
-0.0900617... |
The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain. | Viral RNA-dependent RNA polymerases (RdRps) responsible for the replication of single-strand RNA virus genomes exert their function in the context of complex replication machineries. Within these replication complexes the polymerase activity is often highly regulated by RNA elements, proteins or other domains of multi-... | 25,209,234 | [
-0.3644954,
0.2956747,
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0.283005,
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0.1158197,
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0.0632929,
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0.1055263,
0.4253114,
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-0.314675... |
Osmotic buckling of spherical capsules. | We study the buckling of elastic spherical shells under osmotic pressure with the osmolyte concentration of the exterior solution as a control parameter. We compare our results for the bifurcation behavior with results for buckling under mechanical pressure control, that is, with an empty capsule interior. We find stri... | 25,209,240 | [
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0.03495789,
0.08495887,
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0.08754757,
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0.3336132,
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-0.027510... |
Three mechanisms by which striatal denervation causes breakdown of dopamine signaling. | Progressive loss of nigrostriatal dopamine (DA) neurons is the neuropathological hallmark of Parkinson's disease (PD). Symptoms of the disease can often be treated by DA D2 agonists and thus seem related to disinhibition of the indirect striatal pathway. However, there is no evidence that symptoms arise by low extracel... | 25,209,283 | [
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0.1907118,
0.03094509,
0.4205085,
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Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. | Although dysregulated substance P (SP) has been implicated in the pathophysiology of Parkinson's disease (PD), how SP affects the survival of dopaminergic neurons remains unclear. Here, we found that mice lacking endogenous SP (TAC1(-/-)), but not those deficient in the SP receptor (neurokinin-1 receptor, NK1R), were m... | 25,209,287 | [
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0.02947632,
0.3341025,
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0.1262164,... |
Allocentric versus egocentric representation of remembered reach targets in human cortex. | The location of a remembered reach target can be encoded in egocentric and/or allocentric reference frames. Cortical mechanisms for egocentric reach are relatively well described, but the corresponding allocentric representations are essentially unknown. Here, we used an event-related fMRI design to distinguish human b... | 25,209,289 | [
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A positive autoregulatory BDNF feedback loop via C/EBPβ mediates hippocampal memory consolidation. | Little is known about the temporal progression and regulation of the mechanisms underlying memory consolidation. Brain-derived-neurotrophic-factor (BDNF) has been shown to mediate the maintenance of memory consolidation, but the mechanisms of this regulation remain unclear. Using inhibitory avoidance (IA) in rats, here... | 25,209,292 | [
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0.03216831,
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0.04433142,... |
Sleep slow-wave activity reveals developmental changes in experience-dependent plasticity. | Experience-dependent plasticity, the ability of the brain to constantly adapt to an ever-changing environment, has been suggested to be highest during childhood and to decline thereafter. However, empirical evidence for this is rather scarce. Slow-wave activity (SWA; EEG activity of 1-4.5 Hz) during deep sleep can be u... | 25,209,294 | [
0.2636322,
0.1568286,
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... |
Arsenic(III) detection using electrochemical-chemical-chemical redox cycling at bare indium-tin oxide electrodes. | Sensitive As(III) detection in ground water is of great importance for evaluating the quality of drinking water. We report a sensitive electrochemical method for As(III) detection based on electrochemical-chemical-chemical (ECC) redox cycling involving Ru(IV) [an oxidized species of Ru(III)(NH3)5NH2(2+)], As(III), and ... | 25,209,319 | [
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0.05178398,
0.0993849,
0.4072499,
0.3519664,
0.3526349,
0.171... |
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