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path: "complex_traits_all/test.parquet"
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---
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# 🧬 TraitGym
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Benchmarking DNA Sequence Models for Causal Regulatory Variant Prediction in Human Genetics
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🏆 Leaderboard: https://huggingface.co/spaces/songlab/TraitGym-leaderboard
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## 💻 Code (https://github.com/songlab-cal/TraitGym)
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- Tries to follow [recommended Snakemake structure](https://snakemake.readthedocs.io/en/stable/snakefiles/deployment.html)
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- GPN-Promoter code is in [the main GPN repo](https://github.com/songlab-cal/gpn)
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path: "complex_traits_all/test.parquet"
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---
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# 🧬 TraitGym
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[Benchmarking DNA Sequence Models for Causal Regulatory Variant Prediction in Human Genetics](https://www.biorxiv.org/content/10.1101/2025.02.11.637758v1)
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🏆 Leaderboard: https://huggingface.co/spaces/songlab/TraitGym-leaderboard
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## 💻 Code (https://github.com/songlab-cal/TraitGym)
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- Tries to follow [recommended Snakemake structure](https://snakemake.readthedocs.io/en/stable/snakefiles/deployment.html)
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- GPN-Promoter code is in [the main GPN repo](https://github.com/songlab-cal/gpn)
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## Citation
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[Link to paper](https://www.biorxiv.org/content/10.1101/2025.02.11.637758v1)
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```bibtex
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@article{traitgym,
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author = {Benegas, Gonzalo and Eraslan, Gokcen and Song, Yun S.},
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title = {Benchmarking DNA Sequence Models for Causal Regulatory Variant Prediction in Human Genetics},
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elocation-id = {2025.02.11.637758},
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year = {2025},
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doi = {10.1101/2025.02.11.637758},
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publisher = {Cold Spring Harbor Laboratory},
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URL = {https://www.biorxiv.org/content/early/2025/02/12/2025.02.11.637758},
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eprint = {https://www.biorxiv.org/content/early/2025/02/12/2025.02.11.637758.full.pdf},
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journal = {bioRxiv}
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}
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```
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