Participating in six months of physical activity impairs cognitive functioning.

Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Metastases have genomic aberrations different than those of the primary tumor.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Bronchial responsiveness is higher in the summer than in the winter.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Low saturated fat diets have adverse effects on growth or development of infants.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.


Patients in stable partnerships have a slower progression from HIV to death.

Satellite cell dysfunction is not a key factor in sarcopenia development.

Pyridostatin delays checkpoint activation.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.

Mitochondria play a major role in calcium homeostasis.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Falsified artemisinin family drugs with no active ingredient are generally safe.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Serotonin receptors play a role in depression

Having a main partner lowers survival rates in HIV patients.

Having a main partner increases survival rates in HIV patients.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Some countries have achieved the goal of eradicting malaria.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Higher initial mortality is associated with antidepressant use.


Patients with panic anxiety show increased CSF levels of hypocretin.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Golli-deficient T-cells are dormant in initial clonal expansion.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Distant CREs are more conserved among species.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

NAC encourages the generation of angiotensin-converting enzyme.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of myocardial infarction.

Serotonin receptors play a role in depression

Serotonin receptors have no effect on depression

Hypoglycemia decreases the risk of dementia.

Rapamycin treatment raises G-CSF levels.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.


Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Aspirin encourages the production of PGE2.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

The minor G allele of FOXO3 represses IL-10.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

The innate immune response is efficient at removing small numbers of parasites.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.


Persister cells lead to clinical relapse in cancer patients.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Participating in six months of physical activity impairs cognitive functioning.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Metastases have genomic aberrations different than those of the primary tumor.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Participants who quit smoking reduce lung cancer risk by approximately 5%.


Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Teaching hospitals provide better care than non-teaching hospitals.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

RUNX is a top ranscription factor in skin tissue.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

In the UK, drowning affects boys at a higher rate than girls.

Having a main partner lowers survival rates in HIV patients.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

p16INK4A accumulation is encoded by CDKN2A.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

LSD1 plays a role in transcriptional activation

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.


Physical activity levels have been associated with the differences in VO2max between black and white youth.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Excess nitric oxide is responsible for vasospasm.

Genome size differences in rice are explained by LTR retrotransposon expansion.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

During the primary early antibody response activated B cells express low levels of EBI2.

Obesity is determined in part by genetic factors.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Participating in six months of physical activity impairs cognitive functioning.

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Low saturated fat diets have adverse effects on growth or development of infants.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Low saturated fat diets do not have adverse effects on growth or development of infants.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.


Physical injury activates transgultaminase activity.

Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Some countries have achieved the goal of eradicting malaria.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Bariatric surgery has a deleterious impact on mental health.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Vitamin D deficiency has no effect on the term of child delivery.

Increased calcium levels repress transgultaminase activity.

Increased calcium levels activate transgultaminase activity.

Side effects associated with antidepressants decrease risk of stroke.

Serotonin receptors play a role in depression

Serotonin receptors have no effect on depression

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Autophagy deficiency in the liver protects from insulin resistance.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.


Piezo1 channels are sensors for cell crowding in epithelial cells.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

There is no relation between lupus erythematosus and cardiovascular disease

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

CHEK2 has a significant role in breast cancer

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

β1/Ketel is unable to bind microtubules.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a


Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Vitamin D deficiency has no effect on the term of child delivery.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

AZT given with ribavirin alleviates anemia.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

Patients with panic anxiety show increased CSF levels of hypocretin.

Side effects associated with antidepressants increases risk of myocardial infarction.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.


Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Bronchial responsiveness is higher in the summer than in the winter.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Alirocumab treatment increases apo(a) fractional clearance rate.

Higher initial mortality is associated with antidepressant use.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Metastases have genomic aberrations different than those of the primary tumor.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Mitochondria are uninvolved in processes related to cell signaling.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

Mitochondria play a major role in calcium homeostasis.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.


Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

All six cathelicidins are located on chromosome two.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

High cardiopulmonary fitness causes decreased mortality rate.

Side effects associated with antidepressants decrease risk of stroke.

Choice of specialty is not influenced by debt accrued from medical training.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Tet enzymes activate microRNAs required for iPSC derivation.


Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

The binding orientation of the ML-SA1 activator at hTRPML2 is similar to the binding orientation of the ML-SA1 activator at hTRPML1.

RUNX is a top ranscription factor in skin tissue.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

There are four spatial channels in each hemifield of the auditory cortex of cats.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

p16INK4A accumulation is encoded by CDKN2A.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.


Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Excess nitric oxide is responsible for vasospasm.

Sustained transmission of Avian influenza A between humans is not observed.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

CENP-B inhibits heterochromatin formation

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Obesity is determined in part by genetic factors.

Incidence rates of cervical cancer have increased over time.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.


Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Bronchial responsiveness is the same in the winter and summer seasons.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Esrrb associates with BAF and Mbd3/NURD complexes.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Alirocumab treatment increases apo(a) fractional clearance rate.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Satellite cell dysfunction is not a key factor in sarcopenia development.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.


Proteins synthesized at the growth cone are ubiquitinated at a lower rate than proteins from the cell body.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

High cardiopulmonary fitness causes decreased mortality rate.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

N348I mutations decrease resistance to zidovudine (AZT).

Low saturated fat diets have adverse effects on growth or development of infants.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

The binding orientation of the ML-SA1 activator at hTRPML2 is similar to the binding orientation of the ML-SA1 activator at hTRPML1.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Mitochondria are uninvolved in processes related to cell signaling.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

β1/Ketel is unable to bind microtubules.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Adult tissue-resident macrophages possess a self-renewing capacity.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.


Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

NLRP12 is a positive regulator of T-cell receptor activation.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

Short British students are bullied more than control British students.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

NR5A2 is important in bile acid homeostasis in humans.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Mitochondria play a major role in calcium homeostasis.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Gene expression can be highly variable across genetically identical cells.

Genome size differences in rice are explained by LTR retrotransposon expansion.


Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

NAC encourages the generation of angiotensin-converting enzyme.

Hypoglycemia decreases the risk of dementia.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

IL-10 production by monocytes encourages CD4 + T cell response.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

All six cathelicidins are located on chromosome two.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.


Pyridostatin delays checkpoint activation.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Patients in stable partnerships have a slower progression from HIV to death.

Tuberculosis incidence is correlated with residential crowding in the UK.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

The appearance of brown-like or beige cells primarily occurs in subcutaneous fat, not visceral fat.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

The DESMOND program achieved a significant impact on lifestyles outcomes.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Autophagy deficiency in the liver protects from insulin resistance.

Increased calcium levels repress transgultaminase activity.


Pyridostatin increases telomere fragility in BRCA2-deficient cells.

High levels of copeptin increase risk of diabetes.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Short British students are bullied less than control British students.

Distant CREs are more conserved among species.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.

Increased calcium levels activate transgultaminase activity.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

mTORC2 inhibits xCT antiporter through phosphorylation.

Mitochondria play a major role in calcium homeostasis.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.


RUNX is a top ranscription factor in skin tissue.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Autophagy deficiency in the liver protects from insulin resistance.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Serotonin receptors have no effect on depression

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

G-CSF prevents MDSCs from infiltrating tumors.

The appearance of brown-like or beige cells primarily occurs in subcutaneous fat, not visceral fat.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Notch signalling can occur between tumor cells and stromal cells.

50% of patients exposed to radiation have activated markers of myofibroblasts.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.


Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Side effects associated with antidepressants decrease risk of stroke.

Short British students are bullied more than control British students.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Physical injury activates transgultaminase activity.

IL-10 production by monocytes encourages CD4 + T cell response.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

mTORC2 inhibits xCT antiporter through phosphorylation.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Incidence of sepsis has remained stable between 2009-2014.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

During the primary early antibody response activated B cells express high levels of EBI2.

During the primary early antibody response activated B cells express low levels of EBI2.

Tuberculosis incidence is correlated with residential crowding in the UK.


Rapamycin accelerates aging in fruit flies.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Having a main partner lowers survival rates in HIV patients.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Satellite cell dysfunction is not a key factor in sarcopenia development.

High levels of copeptin increase risk of diabetes.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Sustained transmission of Avian influenza A between humans is not observed.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Bronchial responsiveness is the same in the winter and summer seasons.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Autophagy deficiency in the liver protects from insulin resistance.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Rapamycin treatment raises G-CSF levels.

The innate immune response is efficient at removing small numbers of parasites.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.


Rapamycin treatment raises G-CSF levels.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

The number of Ndc80 complexes varies with cell cycle timing.

Self-advocacy training is not effective at decreasing homelessness.

Transplanted human glial cells are incapable of differentiation within the host animal.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

Higher initial mortality is associated with antidepressant use.

G-CSF prevents MDSCs from infiltrating tumors.

AZT given with ribavirin alleviates anemia.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Patients with panic anxiety show increased CSF levels of hypocretin.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of myocardial infarction.

A deficiency of folate decreases blood levels of homocysteine.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Increased calcium levels activate transgultaminase activity.


Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Choice of specialty is not influenced by debt accrued from medical training.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

High levels of copeptin increase risk of diabetes.

Autophagy deficiency in the liver protects from insulin resistance.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Hypoglycemia decreases the risk of dementia.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Bariatric surgery reduces resolution of diabetes.


Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

The number of Ndc80 complexes varies with cell cycle timing.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

Vitamin D deficiency has no effect on the term of child delivery.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.


Risedronate reduces risk of vertebral and non-vertebral fractures.

mTORC2 inhibits xCT antiporter through phosphorylation.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

β1/Ketel is unable to bind microtubules.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

A deficiency of folate decreases blood levels of homocysteine.

Side effects associated with antidepressants increases risk of myocardial infarction.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

Gastric lavage shows no benefit for acute paraquat poisoning.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.


Roughly 10% of women with chronic pelvic pain have no underlying pathology.

AZT given with ribavirin alleviates anemia.

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Golli-deficient T-cells are dormant in initial clonal expansion.

Gastric lavage shows no benefit for acute paraquat poisoning.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Incidence of sepsis has remained stable between 2009-2014.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Bariatric surgery has a deleterious impact on mental health.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Incidence rates of cervical cancer have increased over time.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.


Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Higher initial mortality is associated with antidepressant use.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

Serotonin receptors have no effect on depression

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

All phenotypes associated with reduced IIS require the gene daf-16.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.


Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Low saturated fat diets have adverse effects on growth or development of infants.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

β1/Ketel is unable to bind microtubules.

Piezo1 channels are sensors for cell crowding in epithelial cells.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.


S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

IL-10 production by monocytes encourages CD4 + T cell response.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Mitochondria play a major role in calcium homeostasis.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

The DESMOND program achieved a significant impact on lifestyles outcomes.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

p16INK4A accumulation is encoded by CDKN2A.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.


S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

There is no relation between lupus erythematosus and cardiovascular disease

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Tet enzymes activate microRNAs required for iPSC derivation.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).


SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

All phenotypes associated with reduced IIS require the gene daf-16.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

NR5A2 is important in bile acid homeostasis in humans.

High cardiopulmonary fitness causes decreased mortality rate.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Autophagy deficiency in the liver protects from insulin resistance.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.


Satellite cell dysfunction is not a key factor in sarcopenia development.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

PEP carboxylase enhances threonine production in E. coli.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Ly6C hi monocytes have a higher inflammatory capacity compared to their Ly6C lo counterparts.

Long-term use of statins showed a increased risk of gallstones followed by cholecystectomy.

The DESMOND program significantly improves biochemical outcomes.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Vitamin D deficiency has no effect on the term of child delivery.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.


Self-advocacy training is not effective at decreasing homelessness.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Some countries have achieved the goal of eradicting malaria.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

Proteins synthesized at the growth cone are ubiquitinated at a lower rate than proteins from the cell body.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.

Bronchial responsiveness is higher in the summer than in the winter.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Having a main partner lowers survival rates in HIV patients.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Higher initial mortality is associated with antidepressant use.

Patients with panic anxiety show increased CSF levels of hypocretin.

Having a main partner increases survival rates in HIV patients.

Bariatric surgery has a deleterious impact on mental health.


Serotonin receptors have no effect on depression

p16INK4A accumulation is encoded by CDKN2A.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Mitochondria are uninvolved in processes related to cell signaling.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

The appearance of brown-like or beige cells primarily occurs in subcutaneous fat, not visceral fat.

Patients with panic anxiety show increased CSF levels of hypocretin.

During the primary early antibody response activated B cells express high levels of EBI2.

Increased calcium levels repress transgultaminase activity.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Serotonin receptors play a role in depression

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of myocardial infarction.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

LSD1 plays a role in transcriptional activation


Serotonin receptors play a role in depression

Some signals for alternative polyadenylation sites are encoded in transposable elements.

Adult tissue-resident macrophages possess a self-renewing capacity.

Aspirin encourages the production of PGE2.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Higher initial mortality is associated with antidepressant use.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.


Short British students are bullied less than control British students.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

There is no relation between lupus erythematosus and cardiovascular disease

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Short British students are bullied more than control British students.

In the UK, drowning affects boys at a higher rate than girls.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Tuberculosis incidence is correlated with residential crowding in the UK.

Teaching hospitals provide better care than non-teaching hospitals.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).


Short British students are bullied more than control British students.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Side effects associated with antidepressants increases risk of myocardial infarction.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.


Side effects associated with antidepressants decrease risk of stroke.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

G-CSF prevents MDSCs from infiltrating tumors.

Suboptimal nutrition is a leading cause of chronic disease

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Side effects associated with antidepressants increases risk of myocardial infarction.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Higher initial mortality is associated with antidepressant use.

Serotonin receptors have no effect on depression

Serotonin receptors play a role in depression

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.


Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Tuberculosis incidence is correlated with residential crowding in the UK.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Esrrb associates with BAF and Mbd3/NURD complexes.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

Adult tissue-resident macrophages possess a self-renewing capacity.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.


Side effects associated with antidepressants increases risk of myocardial infarction.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

NR5A2 is important in bile acid homeostasis in humans.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

The minor G allele of FOXO3 represses IL-10.

IL-10 production by monocytes encourages CD4 + T cell response.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

PEP carboxylase enhances threonine production in E. coli.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Patients with panic anxiety show increased CSF levels of hypocretin.


Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

PEP carboxylase suppresses threonine production in E. coli.

The DESMOND program significantly improves biochemical outcomes.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

N348I mutations decrease resistance to zidovudine (AZT).

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

CHEK2 has a significant role in breast cancer

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

A deficiency of folate decreases blood levels of homocysteine.

A deficiency of vitamin B6 increases blood levels of homocysteine.


Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

All six cathelicidins are located on chromosome two.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.


Some countries have achieved the goal of eradicting malaria.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Ginger is safe for mechanically ventilated patients.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Sustained transmission of Avian influenza A between humans is not observed.

Incidence rates of cervical cancer have increased over time.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

The innate immune response is efficient at removing small numbers of parasites.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Patients in stable partnerships have a slower progression from HIV to death.


Some signals for alternative polyadenylation sites are encoded in transposable elements.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Mitochondria are uninvolved in processes related to cell signaling.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Tuberculosis incidence is correlated with residential crowding in the UK.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Tet enzymes activate microRNAs required for iPSC derivation.


Suboptimal nutrition is a leading cause of chronic disease

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Genetic deletion of JAM-A decreases gut permeability.

Adult tissue-resident macrophages possess a self-renewing capacity.

Golli-deficient T-cells are dormant in initial clonal expansion.

Obesity is determined in part by genetic factors.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Low saturated fat diets have adverse effects on growth or development of infants.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.


Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Physical injury activates transgultaminase activity.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Myelin sheaths play an important role in trophic support.

Mitochondria are uninvolved in processes related to cell signaling.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.


Sustained transmission of Avian influenza A between humans is not observed.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

All six cathelicidins are located on chromosome two.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

A deficiency of folate decreases blood levels of homocysteine.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

50% of patients exposed to radiation have activated markers of myofibroblasts.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Some countries have achieved the goal of eradicting malaria.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

The innate immune response is efficient at removing small numbers of parasites.

Colloid exposure has no effect on morbidity.


Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Myelin sheaths play an important role in trophic support.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

LSD1 plays a role in transcriptional activation

Side effects associated with antidepressants decrease risk of stroke.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Autophagy deficiency in the liver protects from insulin resistance.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Serotonin receptors have no effect on depression

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.


Synaptic activity enhances local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Side effects associated with antidepressants decrease risk of stroke.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Metastases have genomic aberrations different than those of the primary tumor.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

CHEK2 has a significant role in breast cancer

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.


Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

Rapamycin accelerates aging in fruit flies.

Golli-deficient T-cells are dormant in initial clonal expansion.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Serotonin receptors play a role in depression


Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Ginger is safe for mechanically ventilated patients.

Adult tissue-resident macrophages possess a self-renewing capacity.

Bariatric surgery reduces resolution of diabetes.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

High cardiopulmonary fitness causes decreased mortality rate.

There are four spatial channels in each hemifield of the auditory cortex of cats.


T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Bariatric surgery reduces resolution of diabetes.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Genetic deletion of JAM-A decreases gut permeability.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

NLRP12 is a positive regulator of T-cell receptor activation.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

IL-10 production by monocytes encourages CD4 + T cell response.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Golli-deficient T-cells are dormant in initial clonal expansion.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.


T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Having a main partner increases survival rates in HIV patients.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Aspirin encourages the production of PGE2.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.


Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

Rapamycin treatment raises G-CSF levels.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of myocardial infarction.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

During the primary early antibody response activated B cells express low levels of EBI2.

Higher initial mortality is associated with antidepressant use.

During the primary early antibody response activated B cells express high levels of EBI2.

AZT given with ribavirin alleviates anemia.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.


Teaching hospitals provide better care than non-teaching hospitals.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

There is no relation between lupus erythematosus and cardiovascular disease

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

PEP carboxylase suppresses threonine production in E. coli.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Patients in stable partnerships have a slower progression from HIV to death.

Having a main partner increases survival rates in HIV patients.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Choice of specialty is not influenced by debt accrued from medical training.

Bariatric surgery has a deleterious impact on mental health.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Bariatric surgery reduces resolution of diabetes.


Tet enzymes activate microRNAs required for iPSC derivation.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

NAC encourages the generation of angiotensin-converting enzyme.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Cellular aging is uncorrelated with an older appearance.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.


The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Synaptic activity enhances local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Ly6C hi monocytes have a higher inflammatory capacity compared to their Ly6C lo counterparts.

The binding orientation of the ML-SA1 activator at hTRPML2 is similar to the binding orientation of the ML-SA1 activator at hTRPML1.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Side effects associated with antidepressants decrease risk of stroke.

Higher initial mortality is associated with antidepressant use.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Side effects associated with antidepressants increases risk of myocardial infarction.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Serotonin receptors have no effect on depression


The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Rapamycin treatment raises G-CSF levels.

G-CSF prevents MDSCs from infiltrating tumors.

High cardiopulmonary fitness causes decreased mortality rate.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Gene expression can be highly variable across genetically identical cells.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.


The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Bronchial responsiveness is the same in the winter and summer seasons.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Pyridostatin delays checkpoint activation.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Mitochondria play a major role in calcium homeostasis.

mTORC2 inhibits xCT antiporter through phosphorylation.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.


The DESMOND program achieved a significant impact on lifestyles outcomes.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Esrrb associates with BAF and Mbd3/NURD complexes.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

In the UK, drowning affects boys at a higher rate than girls.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

The DESMOND program significantly improves biochemical outcomes.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

Self-advocacy training is not effective at decreasing homelessness.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Vitamin D deficiency has no effect on the term of child delivery.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events


The DESMOND program significantly improves biochemical outcomes.

Gastric lavage shows no benefit for acute paraquat poisoning.

β1/Ketel is unable to bind microtubules.

Side effects associated with antidepressants increases risk of myocardial infarction.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

DUSP4 downregulation activates the Ras-ERK pathway

50% of patients exposed to radiation have activated markers of myofibroblasts.

Genome size differences in rice are explained by LTR retrotransposon expansion.

NLRP12 is a positive regulator of T-cell receptor activation.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

IL-10 production by monocytes encourages CD4 + T cell response.

Some countries have achieved the goal of eradicting malaria.