10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Pyridostatin delays checkpoint activation.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Some countries have achieved the goal of eradicting malaria.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Suboptimal nutrition is a leading cause of chronic disease

Incidence of sepsis has remained stable between 2009-2014.


25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Distant CREs are more conserved among species.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Alirocumab treatment increases apo(a) fractional clearance rate.

Side effects associated with antidepressants decrease risk of stroke.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Higher initial mortality is associated with antidepressant use.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Side effects associated with antidepressants increases risk of myocardial infarction.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Hypoglycemia decreases the risk of dementia.


50% of patients exposed to radiation have activated markers of myofibroblasts.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Transplanted human glial cells are incapable of differentiation within the host animal.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

p16INK4A accumulation is encoded by CDKN2A.

Short British students are bullied more than control British students.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Incidence of sepsis has remained stable between 2009-2014.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Metastases have genomic aberrations different than those of the primary tumor.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Notch signalling can occur between tumor cells and stromal cells.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.


8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Choice of specialty is not influenced by debt accrued from medical training.

Patients in stable partnerships have a slower progression from HIV to death.

Aspirin encourages the production of PGE2.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Incidence of sepsis has remained stable between 2009-2014.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Tuberculosis incidence is correlated with residential crowding in the UK.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Teaching hospitals provide better care than non-teaching hospitals.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.


A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

During the primary early antibody response activated B cells express low levels of EBI2.

In the UK, drowning affects boys at a higher rate than girls.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Bronchial responsiveness is the same in the winter and summer seasons.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Side effects associated with antidepressants decrease risk of stroke.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Side effects associated with antidepressants increases risk of myocardial infarction.

Higher initial mortality is associated with antidepressant use.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.


A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Pyridostatin delays checkpoint activation.

Bronchial responsiveness is higher in the summer than in the winter.

Major vault protein (MVP) functions to decrease tumor aggression.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Some countries have achieved the goal of eradicting malaria.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Sustained transmission of Avian influenza A between humans is not observed.

Patients in stable partnerships have a slower progression from HIV to death.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

There is no relation between lupus erythematosus and cardiovascular disease

Having a main partner lowers survival rates in HIV patients.

Having a main partner increases survival rates in HIV patients.


A deficiency of folate decreases blood levels of homocysteine.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Having a main partner lowers survival rates in HIV patients.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Autophagy deficiency in the liver protects from insulin resistance.

NR5A2 is important in bile acid homeostasis in humans.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Increased calcium levels repress transgultaminase activity.

High levels of copeptin increase risk of diabetes.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

N348I mutations decrease resistance to zidovudine (AZT).

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.


A deficiency of vitamin B6 increases blood levels of homocysteine.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

50% of patients exposed to radiation have activated markers of myofibroblasts.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

mTORC2 inhibits xCT antiporter through phosphorylation.

Gastric lavage shows no benefit for acute paraquat poisoning.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.


APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

The innate immune response is efficient at removing small numbers of parasites.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Colloid exposure has no effect on morbidity.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Genetic deletion of JAM-A decreases gut permeability.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

DUSP4 downregulation activates the Ras-ERK pathway

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

IL-10 production by monocytes encourages CD4 + T cell response.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

The minor G allele of FOXO3 represses IL-10.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.


AZT given with ribavirin alleviates anemia.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Physical injury activates transgultaminase activity.

G-CSF prevents MDSCs from infiltrating tumors.

Patients in stable partnerships have a slower progression from HIV to death.

NAC encourages the generation of angiotensin-converting enzyme.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Having a main partner lowers survival rates in HIV patients.

Alirocumab treatment increases apo(a) fractional clearance rate.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of myocardial infarction.

Rapamycin treatment raises G-CSF levels.

N348I mutations decrease resistance to zidovudine (AZT).

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.


Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

Lithium damages function in the SCA1 mouse model

Mitochondria play a major role in calcium homeostasis.

Bariatric surgery has a deleterious impact on mental health.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

mTORC2 inhibits xCT antiporter through phosphorylation.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Excess nitric oxide is responsible for vasospasm.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.


Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Obesity is determined in part by genetic factors.

Ly6C hi monocytes have a higher inflammatory capacity compared to their Ly6C lo counterparts.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Higher initial mortality is associated with antidepressant use.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Adult tissue-resident macrophages possess a self-renewing capacity.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

F4/80+ macrophages are located in the periosteum.

Myelin sheaths play an important role in trophic support.


Adult tissue-resident macrophages possess a self-renewing capacity.

Participating in six months of physical activity impairs cognitive functioning.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Cellular aging is uncorrelated with an older appearance.

Suboptimal nutrition is a leading cause of chronic disease

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Incidence of sepsis has remained stable between 2009-2014.

p16INK4A accumulation is encoded by CDKN2A.

CENP-B inhibits heterochromatin formation

Mitochondria play a major role in calcium homeostasis.

Mitochondria are uninvolved in processes related to cell signaling.

The innate immune response is efficient at removing small numbers of parasites.


Alirocumab treatment increases apo(a) fractional clearance rate.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Serotonin receptors play a role in depression

Lithium damages function in the SCA1 mouse model

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Low saturated fat diets do not have adverse effects on growth or development of infants.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

AZT given with ribavirin alleviates anemia.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Higher initial mortality is associated with antidepressant use.

Side effects associated with antidepressants increases risk of myocardial infarction.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Aspirin encourages the production of PGE2.

Genetic deletion of JAM-A decreases gut permeability.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer


All phenotypes associated with reduced IIS require the gene daf-16.

The number of Ndc80 complexes varies with cell cycle timing.

Participating in six months of physical activity impairs cognitive functioning.

Golli-deficient T-cells are dormant in initial clonal expansion.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

A deficiency of vitamin B6 increases blood levels of homocysteine.

NLRP12 is a positive regulator of T-cell receptor activation.

The minor G allele of FOXO3 represses IL-10.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Conformational changes of the CD3 complex enable ITAM phosphorylation.

A deficiency of folate decreases blood levels of homocysteine.

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.


All six cathelicidins are located on chromosome two.

N348I mutations decrease resistance to zidovudine (AZT).

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

NR5A2 is important in bile acid homeostasis in humans.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

Incidence rates of cervical cancer have increased over time.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Short British students are bullied more than control British students.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

The number of Ndc80 complexes varies with cell cycle timing.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.


Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Distant CREs are more conserved among species.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

CENP-B inhibits heterochromatin formation

Suboptimal nutrition is a leading cause of chronic disease

Genome size differences in rice are explained by LTR retrotransposon expansion.

Gene expression can be highly variable across genetically identical cells.


Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Physical injury activates transgultaminase activity.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Golli-deficient T-cells are dormant in initial clonal expansion.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Serotonin receptors have no effect on depression

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Side effects associated with antidepressants increases risk of myocardial infarction.

Serotonin receptors play a role in depression

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Patients with panic anxiety show increased CSF levels of hypocretin.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.


An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

NLRP12 is a positive regulator of T-cell receptor activation.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

N348I mutations decrease resistance to zidovudine (AZT).

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.

The number of Ndc80 complexes varies with cell cycle timing.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.


Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Monoclonal antibody targeting of N-cadherin promotes growth.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Satellite cell dysfunction is not a key factor in sarcopenia development.

Notch signalling can occur between tumor cells and stromal cells.

Major vault protein (MVP) functions to decrease tumor aggression.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

The innate immune response is efficient at removing small numbers of parasites.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

AZT given with ribavirin alleviates anemia.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.


Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Gastric lavage shows no benefit for acute paraquat poisoning.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Tuberculosis incidence is correlated with residential crowding in the UK.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.


Aspirin encourages the production of PGE2.

CRY proteins mediate light signal transduction.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

Ly6C hi monocytes have a higher inflammatory capacity compared to their Ly6C lo counterparts.

Tuberculosis incidence is correlated with residential crowding in the UK.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Self-advocacy training is not effective at decreasing homelessness.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

Tet enzymes activate microRNAs required for iPSC derivation.

PEP carboxylase enhances threonine production in E. coli.

PEP carboxylase suppresses threonine production in E. coli.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

High levels of copeptin increase risk of diabetes.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Higher initial mortality is associated with antidepressant use.

Autophagy deficiency in the liver protects from insulin resistance.


Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

The minor G allele of FOXO3 represses IL-10.

In the UK, drowning affects boys at a higher rate than girls.

Suboptimal nutrition is a leading cause of chronic disease

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Vitamin D deficiency has no effect on the term of child delivery.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Low saturated fat diets have adverse effects on growth or development of infants.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Incidence rates of cervical cancer have increased over time.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.


Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Ginger is safe for mechanically ventilated patients.

High cardiopulmonary fitness causes decreased mortality rate.

AZT given with ribavirin alleviates anemia.

Rapamycin treatment raises G-CSF levels.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Tuberculosis incidence is correlated with residential crowding in the UK.

Hypoglycemia decreases the risk of dementia.


Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

Genome size differences in rice are explained by LTR retrotransposon expansion.

CHEK2 has a significant role in breast cancer

Gastric lavage shows no benefit for acute paraquat poisoning.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Obesity is determined in part by genetic factors.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

There are four spatial channels in each hemifield of the auditory cortex of cats.


Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Incidence of sepsis has remained stable between 2009-2014.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

Higher initial mortality is associated with antidepressant use.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Transplanted human glial cells are incapable of differentiation within the host animal.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.


Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.

The binding orientation of the ML-SA1 activator at hTRPML2 is similar to the binding orientation of the ML-SA1 activator at hTRPML1.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Aspirin encourages the production of PGE2.

Bariatric surgery reduces resolution of diabetes.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Satellite cell dysfunction is not a key factor in sarcopenia development.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Metastases have genomic aberrations different than those of the primary tumor.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.


Autophagy deficiency in the liver protects from insulin resistance.

PEP carboxylase suppresses threonine production in E. coli.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

A deficiency of folate decreases blood levels of homocysteine.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

High levels of copeptin increase risk of diabetes.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Increased calcium levels activate transgultaminase activity.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Bariatric surgery reduces resolution of diabetes.


The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Rapamycin treatment raises G-CSF levels.

Persister cells lead to clinical relapse in cancer patients.

NLRP12 is a positive regulator of T-cell receptor activation.

Bronchial responsiveness is the same in the winter and summer seasons.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Cellular aging is uncorrelated with an older appearance.

Adult tissue-resident macrophages possess a self-renewing capacity.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

Hypoglycemia decreases the risk of dementia.


BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

During the primary early antibody response activated B cells express low levels of EBI2.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Bronchial responsiveness is higher in the summer than in the winter.

Suboptimal nutrition is a leading cause of chronic disease

Choice of specialty is not influenced by debt accrued from medical training.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

CHEK2 has a significant role in breast cancer

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.


Bariatric surgery has a deleterious impact on mental health.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

All phenotypes associated with reduced IIS require the gene daf-16.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

Short British students are bullied less than control British students.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

G-CSF prevents MDSCs from infiltrating tumors.

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Teaching hospitals provide better care than non-teaching hospitals.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

There is no relation between lupus erythematosus and cardiovascular disease

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Suboptimal nutrition is a leading cause of chronic disease


Bariatric surgery reduces resolution of diabetes.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

There are four spatial channels in each hemifield of the auditory cortex of cats.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Hypoglycemia decreases the risk of dementia.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Esrrb associates with BAF and Mbd3/NURD complexes.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

Notch signalling can occur between tumor cells and stromal cells.

Autophagy deficiency in the liver protects from insulin resistance.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

AZT given with ribavirin alleviates anemia.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.


Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Low saturated fat diets have adverse effects on growth or development of infants.

Increased calcium levels repress transgultaminase activity.

Excess nitric oxide is responsible for vasospasm.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

IL-10 production by monocytes encourages CD4 + T cell response.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

During the primary early antibody response activated B cells express high levels of EBI2.

During the primary early antibody response activated B cells express low levels of EBI2.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Esrrb associates with BAF and Mbd3/NURD complexes.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.


Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Teaching hospitals provide better care than non-teaching hospitals.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Major vault protein (MVP) functions to decrease tumor aggression.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

Short British students are bullied less than control British students.

Satellite cell dysfunction is not a key factor in sarcopenia development.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Colloid exposure has no effect on morbidity.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

The innate immune response is efficient at removing small numbers of parasites.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.


Bronchial responsiveness is higher in the summer than in the winter.

Cellular aging is uncorrelated with an older appearance.

Transplanted human glial cells are incapable of differentiation within the host animal.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

A deficiency of folate decreases blood levels of homocysteine.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Bronchial responsiveness is the same in the winter and summer seasons.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

High levels of copeptin increase risk of diabetes.

Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Gastric lavage shows no benefit for acute paraquat poisoning.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.


Bronchial responsiveness is the same in the winter and summer seasons.

Increased calcium levels activate transgultaminase activity.

Patients with panic anxiety show increased CSF levels of hypocretin.

RUNX is a top ranscription factor in skin tissue.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.

Long-term use of statins showed a increased risk of gallstones followed by cholecystectomy.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Ginger is safe for mechanically ventilated patients.


C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Pyridostatin delays checkpoint activation.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Choice of specialty is not influenced by debt accrued from medical training.

Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Piezo1 channels are sensors for cell crowding in epithelial cells.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Mitochondria play a major role in calcium homeostasis.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.


C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Lithium damages function in the SCA1 mouse model

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Transplanted human glial cells are incapable of differentiation within the host animal.

Golli-deficient T-cells are dormant in initial clonal expansion.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Increased calcium levels repress transgultaminase activity.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Genome size differences in rice are explained by LTR retrotransposon expansion.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.


C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Gastric lavage shows no benefit for acute paraquat poisoning.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Some countries have achieved the goal of eradicting malaria.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.


CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

High cardiopulmonary fitness causes decreased mortality rate.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Having a main partner increases survival rates in HIV patients.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Bronchial responsiveness is the same in the winter and summer seasons.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

p16INK4A accumulation is encoded by CDKN2A.

CHEK2 has a significant role in breast cancer

DUSP4 downregulation activates the Ras-ERK pathway

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.


CENP-B inhibits heterochromatin formation

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Induction of urokinase receptor signaling in podocytes has no effect on foot process effacement and proteinuria.

Sustained transmission of Avian influenza A between humans is not observed.

Short British students are bullied less than control British students.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

During the primary early antibody response activated B cells express high levels of EBI2.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

During the primary early antibody response activated B cells express low levels of EBI2.


CHEK2 has a significant role in breast cancer

Side effects associated with antidepressants decrease risk of stroke.

Gene expression can be highly variable across genetically identical cells.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

PEP carboxylase suppresses threonine production in E. coli.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

NR5A2 is important in bile acid homeostasis in humans.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

DUSP4 downregulation activates the Ras-ERK pathway


CRY proteins mediate light signal transduction.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Mitochondria are uninvolved in processes related to cell signaling.

Myelin sheaths play an important role in trophic support.

Notch signalling can occur between tumor cells and stromal cells.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Mitochondria play a major role in calcium homeostasis.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.


Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Bariatric surgery reduces resolution of diabetes.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

DUSP4 downregulation activates the Ras-ERK pathway

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

A deficiency of folate decreases blood levels of homocysteine.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Hypoglycemia decreases the risk of dementia.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

A deficiency of vitamin B6 increases blood levels of homocysteine.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Side effects associated with antidepressants increases risk of myocardial infarction.


Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

Mitochondria play a major role in calcium homeostasis.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Pyridostatin delays checkpoint activation.

Falsified artemisinin family drugs with no active ingredient are generally safe.

Low saturated fat diets have adverse effects on growth or development of infants.

AZT given with ribavirin alleviates anemia.

All phenotypes associated with reduced IIS require the gene daf-16.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Self-advocacy training is not effective at decreasing homelessness.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Gene expression can be highly variable across genetically identical cells.

Transplanted human glial cells are incapable of differentiation within the host animal.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Mitochondria are uninvolved in processes related to cell signaling.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.


Cellular aging is uncorrelated with an older appearance.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.

CHEK2 has a significant role in breast cancer

Rapamycin treatment raises G-CSF levels.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

During the primary early antibody response activated B cells express high levels of EBI2.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Adult tissue-resident macrophages possess a self-renewing capacity.

Obesity is determined in part by genetic factors.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.


Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Participating in six months of physical activity impairs cognitive functioning.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

Serotonin receptors play a role in depression

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Synaptic activity enhances local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

The innate immune response is efficient at removing small numbers of parasites.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Sustained transmission of Avian influenza A between humans is not observed.

In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Some countries have achieved the goal of eradicting malaria.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.


Choice of specialty is not influenced by debt accrued from medical training.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Increased calcium levels repress transgultaminase activity.

Vitamin D deficiency has no effect on the term of child delivery.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Aspirin encourages the production of PGE2.

Teaching hospitals provide better care than non-teaching hospitals.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Bariatric surgery has a deleterious impact on mental health.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Bariatric surgery reduces resolution of diabetes.

There is no relation between lupus erythematosus and cardiovascular disease

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.


Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.

Choice of specialty is not influenced by debt accrued from medical training.

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

All six cathelicidins are located on chromosome two.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Serotonin receptors play a role in depression

Major vault protein (MVP) functions to decrease tumor aggression.

Roughly one in two thousand UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Excess nitric oxide is responsible for vasospasm.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

Autophagy deficiency in the liver protects from insulin resistance.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.


PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Obesity is determined in part by genetic factors.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Tuberculosis incidence is correlated with residential crowding in the UK.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Excess nitric oxide is responsible for vasospasm.

Colloid exposure has no effect on morbidity.

Gastric lavage shows no benefit for acute paraquat poisoning.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

A deficiency of folate decreases blood levels of homocysteine.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Hypoglycemia decreases the risk of dementia.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.


Colloid exposure has no effect on morbidity.

N348I mutations decrease resistance to zidovudine (AZT).

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Hypoglycemia decreases the risk of dementia.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

Serotonin receptors play a role in depression

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Sustained transmission of Avian influenza A between humans is not observed.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.


Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

There are four spatial channels in each hemifield of the auditory cortex of cats.

PEP carboxylase suppresses threonine production in E. coli.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

Mitochondria are uninvolved in processes related to cell signaling.

Low saturated fat diets have adverse effects on growth or development of infants.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Side effects associated with antidepressants decrease risk of stroke.

Higher initial mortality is associated with antidepressant use.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Side effects associated with antidepressants increases risk of myocardial infarction.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.


Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

The number of Ndc80 complexes varies with cell cycle timing.

Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

The DESMOND program significantly improves biochemical outcomes.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Patients with panic anxiety show increased CSF levels of hypocretin.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

A deficiency of folate decreases blood levels of homocysteine.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

CHEK2 has a significant role in breast cancer

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Metastases have genomic aberrations different than those of the primary tumor.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.


Conformational changes of the CD3 complex enable ITAM phosphorylation.

Increased calcium levels activate transgultaminase activity.

PEP carboxylase enhances threonine production in E. coli.

IL-10 production by monocytes encourages CD4 + T cell response.

All six cathelicidins are located on chromosome two.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

The minor G allele of FOXO3 represses IL-10.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Inhibiting HDAC6 decreases survival of mice with ARID1A mutated tumors.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

p16INK4A accumulation is encoded by CDKN2A.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

LSD1 plays a role in transcriptional activation

The number of Ndc80 complexes varies with cell cycle timing.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.


Consumption of whole fruits reduces the risk of type 2 diabetes.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Having a main partner increases survival rates in HIV patients.

Self-advocacy training is not effective at decreasing homelessness.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Monoclonal antibody targeting of N-cadherin promotes growth.

Excess nitric oxide is responsible for vasospasm.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

AZT given with ribavirin alleviates anemia.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Autophagy deficiency in the liver protects from insulin resistance.

Low saturated fat diets have adverse effects on growth or development of infants.

Bariatric surgery reduces resolution of diabetes.

Suboptimal nutrition is a leading cause of chronic disease

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.


Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Incidence of sepsis has remained stable between 2009-2014.

Long-term use of statins showed a increased risk of gallstones followed by cholecystectomy.

During the primary early antibody response activated B cells express high levels of EBI2.

Choice of specialty is not influenced by debt accrued from medical training.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Bariatric surgery has a deleterious impact on mental health.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Proteins synthesized at the growth cone are ubiquitinated at a lower rate than proteins from the cell body.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

Genome size differences in rice are explained by LTR retrotransposon expansion.


Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

AZT given with ribavirin alleviates anemia.

Some countries have achieved the goal of eradicting malaria.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.

CRY proteins mediate light signal transduction.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

De novo assembly of sequence data has longer contigs than unassembled sequence data.


Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Low saturated fat diets have adverse effects on growth or development of infants.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Teaching hospitals provide better care than non-teaching hospitals.

Higher initial mortality is associated with antidepressant use.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Choice of specialty is not influenced by debt accrued from medical training.

Participants who quit smoking reduce lung cancer risk by approximately 5%.


Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

During the primary early antibody response activated B cells express high levels of EBI2.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Gastric lavage shows no benefit for acute paraquat poisoning.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Mitochondria play a major role in calcium homeostasis.

Mitochondria are uninvolved in processes related to cell signaling.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

mTORC2 inhibits xCT antiporter through phosphorylation.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.


Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Participating in six months of physical activity impairs cognitive functioning.

Major vault protein (MVP) functions to decrease tumor aggression.

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Tuberculosis incidence is correlated with residential crowding in the UK.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Notch signalling can occur between tumor cells and stromal cells.

Suboptimal nutrition is a leading cause of chronic disease

Pyridostatin delays checkpoint activation.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.

Self-advocacy training is not effective at decreasing homelessness.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

A deficiency of folate decreases blood levels of homocysteine.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

NR5A2 is important in bile acid homeostasis in humans.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Osteocytes are not associated with G-CSF induced HSPC mobilization.


DUSP4 downregulation activates the Ras-ERK pathway

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

p16INK4A accumulation is encoded by CDKN2A.

Esrrb associates with BAF and Mbd3/NURD complexes.

The innate immune response is efficient at removing small numbers of parasites.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

During the primary early antibody response activated B cells express low levels of EBI2.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).


De novo assembly of sequence data has longer contigs than unassembled sequence data.

Patients in stable partnerships have a slower progression from HIV to death.

Alirocumab treatment increases apo(a) fractional clearance rate.

Transplanted human glial cells are incapable of differentiation within the host animal.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Some countries have achieved the goal of eradicting malaria.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

The appearance of brown-like or beige cells primarily occurs in subcutaneous fat, not visceral fat.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Gene expression can be highly variable across genetically identical cells.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.


Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

All phenotypes associated with reduced IIS require the gene daf-16.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Excess nitric oxide is responsible for vasospasm.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

V-9302 causes antitumor responses by increasing cell death and oxidative stress.

Serotonin receptors play a role in depression

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Autophagy deficiency in the liver protects from insulin resistance.

Cellular aging is uncorrelated with an older appearance.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.