Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

IL-10 production by monocytes encourages CD4 + T cell response.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

Hypoglycemia decreases the risk of dementia.


Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

Pyridostatin delays checkpoint activation.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

Serotonin receptors have no effect on depression

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

N348I mutations decrease resistance to zidovudine (AZT).

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.


Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Serotonin receptors play a role in depression

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Ginger is safe for mechanically ventilated patients.

High cardiopulmonary fitness causes decreased mortality rate.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

A deficiency of folate decreases blood levels of homocysteine.


Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Monoclonal antibody targeting of N-cadherin promotes growth.

Low saturated fat diets have adverse effects on growth or development of infants.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

mTORC2 inhibits xCT antiporter through phosphorylation.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Serotonin receptors have no effect on depression

Serotonin receptors play a role in depression

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Patients with panic anxiety show increased CSF levels of hypocretin.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Vitamin D deficiency has no effect on the term of child delivery.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

LSD1 plays a role in transcriptional activation


Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Bariatric surgery reduces resolution of diabetes.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

F4/80+ macrophages are located in the periosteum.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Incidence of sepsis has remained stable between 2009-2014.

Bronchial responsiveness is higher in the summer than in the winter.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

N348I mutations decrease resistance to zidovudine (AZT).

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

AZT given with ribavirin alleviates anemia.

Side effects associated with antidepressants increases risk of myocardial infarction.

A deficiency of vitamin B6 increases blood levels of homocysteine.


Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

F4/80+ macrophages are located in the periosteum.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Vitamin D deficiency has no effect on the term of child delivery.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

NLRP12 is a positive regulator of T-cell receptor activation.

DUSP4 downregulation activates the Ras-ERK pathway

mTORC2 inhibits xCT antiporter through phosphorylation.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Notch signalling can occur between tumor cells and stromal cells.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Serotonin receptors play a role in depression

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.


Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Lithium damages function in the SCA1 mouse model

NAC encourages the generation of angiotensin-converting enzyme.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

All phenotypes associated with reduced IIS require the gene daf-16.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

PEP carboxylase suppresses threonine production in E. coli.

PEP carboxylase enhances threonine production in E. coli.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

F4/80+ macrophages are located in the periosteum.

Autophagy deficiency in the liver protects from insulin resistance.

Aspirin encourages the production of PGE2.


Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Distant CREs are more conserved among species.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Vitamin D deficiency has no effect on the term of child delivery.

Incidence of sepsis has remained stable between 2009-2014.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Patients in stable partnerships have a slower progression from HIV to death.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Colloid exposure has no effect on morbidity.

Having a main partner lowers survival rates in HIV patients.


Distant CREs are more conserved among species.

G-CSF prevents MDSCs from infiltrating tumors.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

IL-10 production by monocytes encourages CD4 + T cell response.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Adult tissue-resident macrophages possess a self-renewing capacity.

Supracellular actomyosin structures are found at boundaries in Drosophila wing imaginal discs.

Gene expression can be highly variable across genetically identical cells.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.


During the primary early antibody response activated B cells express high levels of EBI2.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

High cardiopulmonary fitness causes decreased mortality rate.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Higher initial mortality is associated with antidepressant use.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Aspirin encourages the production of PGE2.

Alirocumab treatment increases apo(a) fractional clearance rate.

The minor G allele of FOXO3 represses IL-10.

Mitochondria are uninvolved in processes related to cell signaling.

G-CSF prevents MDSCs from infiltrating tumors.

During the primary early antibody response activated B cells express low levels of EBI2.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

IL-10 production by monocytes encourages CD4 + T cell response.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.


During the primary early antibody response activated B cells express low levels of EBI2.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

Choice of specialty is not influenced by debt accrued from medical training.

Short British students are bullied more than control British students.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.


Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.

NLRP12 is a positive regulator of T-cell receptor activation.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Notch signalling can occur between tumor cells and stromal cells.

NR5A2 is important in bile acid homeostasis in humans.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

During the primary early antibody response activated B cells express high levels of EBI2.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Near-infrared wavelengths decrease penetration depth in fiberoptic confocal microscopy.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.


Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

AZT given with ribavirin alleviates anemia.

Myelin sheaths play an important role in trophic support.

RUNX is a top ranscription factor in skin tissue.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

p16INK4A accumulation is encoded by CDKN2A.

Gastric lavage shows no benefit for acute paraquat poisoning.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Serotonin receptors have no effect on depression

Serotonin receptors play a role in depression

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.


Esrrb associates with BAF and Mbd3/NURD complexes.

C. elegans germlines lose their immortal character when nuclear RNAi is disabled.

Serotonin receptors have no effect on depression

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Pyridostatin increases telomere fragility in BRCA2-deficient cells.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

Rapamycin accelerates aging in fruit flies.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

During the primary early antibody response activated B cells express high levels of EBI2.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

During the primary early antibody response activated B cells express low levels of EBI2.

mTORC2 inhibits xCT antiporter through phosphorylation.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.


Excess nitric oxide is responsible for vasospasm.

Metastases have genomic aberrations different than those of the primary tumor.

Adult tissue-resident macrophages possess a self-renewing capacity.

Physical injury activates transgultaminase activity.

CRY proteins mediate light signal transduction.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Choice of specialty is not influenced by debt accrued from medical training.

Participating in six months of physical activity impairs cognitive functioning.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

NAC stabilizes NO to reduce the effect of contrast agents on renal functions.

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

Increased calcium levels activate transgultaminase activity.

Autophagy deficiency in the liver protects from insulin resistance.

Increased calcium levels repress transgultaminase activity.


Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Autophagy deficiency in the liver protects from insulin resistance.

During the primary early antibody response activated B cells express high levels of EBI2.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Major vault protein (MVP) functions to decrease tumor aggression.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

p16INK4A accumulation is encoded by CDKN2A.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

IL-10 production by monocytes encourages CD4 + T cell response.

During the primary early antibody response activated B cells express low levels of EBI2.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.


F4/80+ macrophages are located in the periosteum.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Having a main partner lowers survival rates in HIV patients.

Rapamycin treatment raises G-CSF levels.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Excess nitric oxide is responsible for vasospasm.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

Adult tissue-resident macrophages possess a self-renewing capacity.

Adult tissue-resident macrophages are maintained independent of circulating monocytes.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

The number of Ndc80 complexes varies with cell cycle timing.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

Ly6C hi monocytes have a higher inflammatory capacity compared to their Ly6C lo counterparts.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.


Falsified artemisinin family drugs with no active ingredient are generally safe.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Side effects associated with antidepressants decrease risk of stroke.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

N348I mutations decrease resistance to zidovudine (AZT).

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

AZT given with ribavirin alleviates anemia.

Alirocumab treatment increases apo(a) fractional clearance rate.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

All six cathelicidins are located on chromosome two.


Falsified artemisinin family drugs with no active ingredient can be life-threatening.

All six cathelicidins are located on chromosome two.

F4/80+ macrophages are located in the periosteum.

Participating in six months of physical activity impairs cognitive functioning.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Esrrb associates with BAF and Mbd3/NURD complexes.

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Short British students are bullied more than control British students.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Side effects associated with antidepressants decrease risk of stroke.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.


Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

A deficiency of folate decreases blood levels of homocysteine.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

NR5A2 is important in bile acid homeostasis in humans.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is ineffective at treating KRAS mutant tumors.

Gene expression can be highly variable across genetically identical cells.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Hypoglycemia decreases the risk of dementia.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Obesity is determined in part by genetic factors.


Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Risedronate reduces risk of vertebral and non-vertebral fractures.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

CENP-B inhibits heterochromatin formation

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Higher initial mortality is associated with antidepressant use.

p16INK4A accumulation is encoded by CDKN2A.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

LSD1 plays a role in transcriptional activation

Adipocytes in major adipose depots descend from cells with a history of Pdgfra expression.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to suppress motility along stromal surfaces.

The PDPN gene activates the C-type lectin receptor (CLEC-2).

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.


For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Myelin sheaths play an important role in trophic support.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Vitamin D deficiency has no effect on the term of child delivery.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

In the UK, drowning affects boys at a higher rate than girls.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

Low saturated fat diets do not have adverse effects on growth or development of infants.


Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Lithium damages function in the SCA1 mouse model

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Colloid exposure has no effect on morbidity.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

The DESMOND program achieved a significant impact on lifestyles outcomes.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Delayed sleep phase disorder is associated with a dominant coding variation the core circadian clock gene CRY1.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Mitochondria play a major role in calcium homeostasis.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

Mitochondria are uninvolved in processes related to cell signaling.

The minor G allele of FOXO3 represses IL-10.


Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Mitochondria play a major role in calcium homeostasis.

Pyridostatin delays checkpoint activation.

F4/80+ macrophages are located in the periosteum.

Short British students are bullied less than control British students.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

CHEK2 has a significant role in breast cancer

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

CENP-B inhibits heterochromatin formation

mTORC2 inhibits xCT antiporter through phosphorylation.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).


Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Side effects associated with antidepressants increases risk of myocardial infarction.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

The minor G allele of FOXO3 represses IL-10.

Near-infrared wavelengths increase penetration depth in fiberoptic confocal microscopy.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Bronchial responsiveness is the same in the winter and summer seasons.

Some countries have achieved the goal of eradicting malaria.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Teaching hospitals provide better care than non-teaching hospitals.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

Having a main partner lowers survival rates in HIV patients.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Suboptimal nutrition is a leading cause of chronic disease

Patients in stable partnerships have a slower progression from HIV to death.


G-CSF prevents MDSCs from infiltrating tumors.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

AZT given with ribavirin alleviates anemia.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Induction of urokinase receptor signaling in podocytes has no effect on foot process effacement and proteinuria.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Rapamycin treatment raises G-CSF levels.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Normal granulomas formed in the absence of TNF-␣ despite increased bacterial growth.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB exhibit a strong affinity for phospholipids.


GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

Distant CREs are more conserved among species.

Transplanted human glial cells are incapable of differentiation within the host animal.

Falsified artemisinin family drugs with no active ingredient are generally safe.

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Golli-deficient T-cells are dormant in initial clonal expansion.

Chronic aerobic exercise alters endothelial function, impairing vasodilating mechanisms mediated by NO.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Increased calcium levels activate transgultaminase activity.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

NR5A2 is important in bile acid homeostasis in humans.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis


Gastric lavage shows no benefit for acute paraquat poisoning.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Incidence rates of cervical cancer have increased over time.

Higher initial mortality is associated with antidepressant use.

CENP-B inhibits heterochromatin formation

Notch signalling can occur between tumor cells and stromal cells.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Vitamin D deficiency has no effect on the term of child delivery.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Colloid exposure has no effect on morbidity.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Side effects associated with antidepressants increases risk of myocardial infarction.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Side effects associated with antidepressants decrease risk of stroke.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.


Gene expression can be highly variable across genetically identical cells.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

In the UK, drowning affects boys at a higher rate than girls.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

All phenotypes associated with reduced IIS require the gene daf-16.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

High cardiopulmonary fitness causes decreased mortality rate.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

The number of Ndc80 complexes varies with cell cycle timing.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.


Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

CRY proteins mediate light signal transduction.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are not required for recovery from spinal cord injury.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Esrrb associates with BAF and Mbd3/NURD complexes.

MUC1-C inhibits the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

p16INK4A accumulation is encoded by CDKN2A.

All phenotypes associated with reduced IIS require the gene daf-16.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.


Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Alirocumab treatment increases apo(a) fractional clearance rate.

Occipital activation levels are not correlated with auditory spatial performance in parietal regions of the brain.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Excess nitric oxide is responsible for vasospasm.

Choice of specialty is not influenced by debt accrued from medical training.

Autophagy deficiency in the liver protects from insulin resistance.

The binding orientation of the ML-SA1 activator at hTRPML2 is similar to the binding orientation of the ML-SA1 activator at hTRPML1.

Long-term use of statins showed a decreased risk of gallstones followed by cholecystectomy.

Obesity is determined in part by genetic factors.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

IL-10 production by monocytes encourages CD4 + T cell response.

Low saturated fat diets have adverse effects on growth or development of infants.


Genetic deletion of JAM-A decreases gut permeability.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Increased calcium levels activate transgultaminase activity.

50% of patients exposed to radiation have activated markers of myofibroblasts.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Monoclonal antibody targeting of N-cadherin promotes growth.

Alirocumab treatment increases apo(a) fractional clearance rate.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Genome size differences in rice are explained by LTR retrotransposon expansion.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

A deficiency of vitamin B6 increases blood levels of homocysteine.


Genome size differences in rice are explained by LTR retrotransposon expansion.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Gastric lavage shows no benefit for acute paraquat poisoning.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Diminished ovarian reserve cannot be used in isolation as an indicator of infertility in a non-infertile population.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Gene expression can be highly variable across genetically identical cells.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Coordinated stabilization of kinetochore-microtubule attachments occurs at the prometaphase to metaphase transition.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.


Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Having a main partner lowers survival rates in HIV patients.

Localization of PIN1 in the Arabidopsis embryo requires VPS9a

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Bariatric surgery reduces resolution of diabetes.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

Major vault protein (MVP) functions to decrease tumor aggression.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Piezo1 channels are sensors for cell crowding in epithelial cells.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

A deficiency of folate decreases blood levels of homocysteine.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.


Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Self-advocacy training is not effective at decreasing homelessness.

The appearance of brown-like or beige cells primarily occurs in subcutaneous fat, not visceral fat.

There is no relation between lupus erythematosus and cardiovascular disease

There are four spatial channels in each hemifield of the auditory cortex of cats.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.

Obesity is determined in part by genetic factors.

Mitochondria play a major role in calcium homeostasis.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Short British students are bullied less than control British students.


Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Pseudoknots alter gene expression by inducing ribosomal frameshifts in viruses.

KLF4 prevents VSMCs from acquiring genetic characteristics of other cell types within atherosclerotic lesions.

Electromagnetic interference has no effect on Radio Frequency Identification (RFID) readability and reading distances.

A country's Vaccine Alliance (GAVI) eligibility is associated with accelerated adoption of the Hub vaccine.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Hypoglycemia decreases the risk of dementia.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Mitochondria are uninvolved in processes related to cell signaling.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Ginger is safe for mechanically ventilated patients.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Bronchial responsiveness is higher in the summer than in the winter.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Bronchial responsiveness is the same in the winter and summer seasons.

Consumption of whole fruits reduces the risk of type 2 diabetes.

Gastric lavage shows no benefit for acute paraquat poisoning.


Ginger is safe for mechanically ventilated patients.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

In the UK, drowning affects boys at a higher rate than girls.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Genome size differences in rice are explained by LTR retrotransposon expansion.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Transplanted human glial cells are incapable of differentiation within the host animal.

IL-10 production by monocytes encourages CD4 + T cell response.

AZT given with ribavirin alleviates anemia.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

Side effects associated with antidepressants decrease risk of stroke.


Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

High levels of copeptin increase risk of diabetes.

Microarray results from culture-amplified mixtures of serotypes correlate well microarray results from uncultured mixtures.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Valproic acid (VPA) treatment allows reprogramming by the microRNA cluster miR302/367.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Tuberculosis-induced granulomas express immune system protein signatures similar to those of the surrounding tissue.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

RUNX is a top ranscription factor in skin tissue.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.


Golli-deficient T-cells are dormant in initial clonal expansion.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

The periosteum consists of 2 layers: the inner layer on the periosteal surface with monocyte/macrophage-lineage cells, osteoblastic cells, and abundant periostin; and the outer layer, consisting of collagens, blood vessels, and nerve endings.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

There is no relation between lupus erythematosus and cardiovascular disease

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

IL-10 production by monocytes encourages CD4 + T cell response.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

NLRP12 is a positive regulator of T-cell receptor activation.

Transplanted human glial cells are incapable of differentiation within the host animal.


Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Suboptimal nutrition is a leading cause of chronic disease

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Nrde-3 facilitates heritable silencing in C. elegans by transporting secondary siRNAs to the nucleus.

Sustained transmission of Avian influenza A between humans is not observed.

There are four spatial channels in each hemifield of the auditory cortex of cats.

IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

Gastric lavage shows no benefit for acute paraquat poisoning.

Ginger is hazardous to mechanically ventilated patients, because these patients are susceptible to mucosal lesions and ulcers.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.


Having a main partner increases survival rates in HIV patients.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

Long-term use of statins showed a increased risk of gallstones followed by cholecystectomy.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

G-CSF prevents MDSCs from infiltrating tumors.

Genes regulated by Esrrb transcription factor are unaffected by Mbd3 function.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Deletion of αvβ8 results in a spontaneous inflammatory phenotype.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Having a main partner lowers survival rates in HIV patients.

Patients in stable partnerships have a slower progression from HIV to death.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Some countries have achieved the goal of eradicting malaria.

Higher initial mortality is associated with antidepressant use.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Self-advocacy training is not effective at decreasing homelessness.


Having a main partner lowers survival rates in HIV patients.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

Pretreatment with the Arp2/3 inhibitor CK-666 is not associated with lamelliopodia formation.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

Cell autonomous sex determination in somatic cells does not occur in Passeriformes.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

CRY proteins mediate light signal transduction.

Participants who quit smoking reduce lung cancer risk by approximately 5%.


Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.

25% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Vitamin D deficiency has no effect on the term of child delivery.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Correlative electron microscopy and superresolution fluorescence imaging are imaging techniques.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

Autologous transplantation of mesenchymal stem cells has worse graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Intramembrane cleavage by SPP helps facilitate in the degradation of proteins with a complex membrane orientation.

Glucose restriction to 0.05% increases RLS (replicative life span) by 20-40% in S. cerevisiae.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Decreases in region specific aerobic glycolysis in aged humans slows aging induced changes in brain glucose metabolism.

Autophagy deficiency in the liver protects from insulin resistance.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

SOD1 integrates oxygen and glucose signals to repress cellular respiration.

Increased calcium levels activate transgultaminase activity.


Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Obesity is determined in part by genetic factors.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Physical injury activates transgultaminase activity.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Bariatric surgery reduces resolution of diabetes.

50% of patients exposed to radiation have activated markers of myofibroblasts.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Patients in stable partnerships have a slower progression from HIV to death.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

IL-10 production by monocytes encourages CD4 + T cell response.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.


Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

There is no relation between lupus erythematosus and cardiovascular disease

LSD1 plays a role in transcriptional activation

C-Met is involved in epithelial-mesenchymal transition in tumor cells.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

CHEK2 has a significant role in breast cancer

Having a main partner increases survival rates in HIV patients.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.


High cardiopulmonary fitness causes decreased mortality rate.

Mitochondria play a major role in calcium homeostasis.

Short British students are bullied more than control British students.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

Alirocumab treatment increases apo(a) fractional clearance rate.

Bariatric surgery has a deleterious impact on mental health.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Polyglutamine binding protein 1 (PQBP1) is the co-receptor of HIV-DNA to trigger cell-autonomous antiviral responses.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

The DESMOND program achieved a significant impact on lifestyles outcomes.

Tuberculosis incidence is correlated with residential crowding in the UK.

Higher initial mortality is associated with antidepressant use.

Hypoglycemia decreases the risk of dementia.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

There is no relation between lupus erythematosus and cardiovascular disease

Suboptimal nutrition is a leading cause of chronic disease


High levels of copeptin increase risk of diabetes.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

Decreases in region specific aerobic glycolysis in aged humans causes aging induced changes in brain glucose metabolism.

Hypoglycemia decreases the risk of dementia.

Serotonin receptors have no effect on depression

Consumption of whole fruits reduces the risk of type 2 diabetes.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving cancer metastasis.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Side effects associated with antidepressants decrease risk of stroke.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Low saturated fat diets have adverse effects on growth or development of infants.

Autophagy deficiency in the liver protects from insulin resistance.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Side effects associated with antidepressants increases risk of myocardial infarction.

A deficiency of folate decreases blood levels of homocysteine.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.


High methylation levels within individual DNA molecules correlates with high nucleosome occupancy across species.

Electrophysiological changes in motor neurons have been observed in patients with amyotrophic lateral sclerosis.

Presence of stemloops is important for reverse transcription in short interspersed nuclear elements (SINEs).

Oral ibandronate increases relative risk of new vertebral fractures and clinical vertebral fractures in women.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Persister cells lead to clinical relapse in cancer patients.

Side effects associated with antidepressants increases risk of myocardial infarction.

Somatic missense mutations in NT5C2 are not associated with relapse of acute lymphoblastic leukemia.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Some signals for alternative polyadenylation sites are encoded in transposable elements.

Ultrafine Anaphase Bridges represent a mechanism for resolving partially-replicated stretches of DNA.

Gene expression can be highly variable across genetically identical cells.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

The actual sequences of CP-1 and CR-5 regions are evolutionarily conserved throughout most eukaryotes.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.


High methylation levels within individual DNA molecules correlates with low nucleosome occupancy across species.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Rapamycin treatment raises G-CSF levels.

All six cathelicidins are located on chromosome two.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Pyridostatin delays checkpoint activation.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Induction of urokinase receptor signaling in podocytes has no effect on foot process effacement and proteinuria.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.


Higher initial mortality is associated with antidepressant use.

Deficiency of Tetraspanin-3 causes improved stem cell-renewal and slows disease propagation.

Amitriptyline ineffective as a treatment for chronic tension-type headaches.

IL-10 production by monocytes encourages CD4 + T cell response.

DUSP4 downregulation activates the Ras-ERK pathway

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is more cost-effective than the 10% risk threshold strategy.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

APOE4 expression in iPSC-derived neurons results in increased tau phosphorylation.

β1/Ketel is unable to bind microtubules.

Side effects associated with antidepressants decrease risk of stroke.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Side effects associated with antidepressants increases risk of myocardial infarction.

Patients with panic anxiety show increased CSF levels of hypocretin.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Taking anti-depresents is associated with a increase in the Aβ level in the brain of experimental animals.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.


Hypertension can be accurately diagnosed with ambulatory blood pressure monitoring.

IL-10 production by monocytes encourages CD4 + T cell response.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is nonessential for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

Short British students are bullied less than control British students.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

An N-formyl group on M3 molecules suppresss strong binding to the second position of the groove.

Ginger is safe for mechanically ventilated patients.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Fibroblast growth factor 21 icreases vulnerability to atherosclerosis by modulating adiponectin and SREBP2 levels.

Rates of hypertension in patients type 2 diabetes mellitus are similar to those in non-diabetic subjects.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Bariatric surgery reduces resolution of diabetes.

Excess nitric oxide is responsible for vasospasm.

High levels of copeptin increase risk of diabetes.

Bronchial responsiveness is higher in the summer than in the winter.

Thigh-length graduated compression stockings (GCS) reduced deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Side effects associated with antidepressants decrease risk of stroke.


Hypoglycemia decreases the risk of dementia.

Serotonin receptors have no effect on depression

BRCA 1 mutation carriers' risk of breast and ovarian cancer  is not influence by the location of the mutation.

Genetic deletion of JAM-A decreases gut permeability.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

Colloid exposure has no effect on morbidity.

Pattern recognition receptors are transcripts determinant for resistance to Plasmodium infection.

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Patients with panic anxiety show increased CSF levels of hypocretin.

Higher initial mortality is associated with antidepressant use.

Side effects associated with antidepressants increases risk of mortality in postmenopausal women.

Side effects associated with antidepressants increases risk of myocardial infarction.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.


IFI16 promotes STING phosphorylation and translocation, resulting in elevated activation of STING induced by cGAMP.

Proteins synthesized at the growth cone are ubiquitinated at a lower rate than proteins from the cell body.

Medicare beneficiaries experienced a median delay of 2.4 days between lung cancer diagnosis and initiation of chemotherapy in 2006.

Short British students are bullied less than control British students.

S-nitrosylated GAPDH physiologically transnitrosylates DNA-activated protein kinase.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Transcription factor EB prevents transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Piezo1 channels are sensors for cell crowding in epithelial cells.

PRC1-bound plasmids sediment at a faster rate in unbound plasmids than in sucrose gradients.

Deltex has been shown to interact with eIF3f, a DUB required for Notch activation process.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

During the primary early antibody response activated B cells express high levels of EBI2.

During the primary early antibody response activated B cells express low levels of EBI2.

Conformational changes of the CD3 complex enable ITAM phosphorylation.

The phosphorylation of Drp1 at S616 site promotes its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

p16INK4A accumulation is encoded by CDKN2A.

Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

mTORC2 inhibits xCT antiporter through phosphorylation.


IL-10 production by monocytes encourages CD4 + T cell response.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

NAC encourages the generation of angiotensin-converting enzyme.

Falsified artemisinin family drugs with no active ingredient can be life-threatening.

Participating in six months of physical activity impairs cognitive functioning.

Motor neurons from patients with amyotrophic lateral sclerosis have electrophysiological changes relative to healthy patients.

Lysine histone demethylase inhibitor JIB 04 is primarily active against KDM5A.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Whole brain radiotherapy reduces the occurrence of new brain metastases.

Proteins synthesized at the growth cone are ubiquitinated at a lower rate than proteins from the cell body.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

The minor G allele of FOXO3 represses IL-10.

NLRP12 is a positive regulator of T-cell receptor activation.

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.


Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

A deficiency of folate decreases blood levels of homocysteine.

Asymptomatic bacteriuria increases risk for preterm delivery and low birth weight.

There is a neuroprotective effect of Trpm4 inhibition in mice and rats.

Transient IFN-γ exposure leads to long-lived infammatory responses in cancer cells due to IFN-γ retention on the cell surface.

Transplanted human glial cells are incapable of differentiation within the host animal.

Major vault protein (MVP) functions to decrease tumor aggression.

Short British students are bullied less than control British students.

The center of the granuloma in an immune cell induces an anti-inflammatory immune response.

Therapeutics receiving accelerated approval encounter a higher frequency of post-marketing safety events

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Genomic instability in leukemia cells results from a decrease in reactive oxygen species from oncogene activation.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Polyploidization in megakaryocytes occurs in the presence of an aberrant mitosis.

Phosphorylation of the ATM protein regulates DNA damage-induced neuronal death.

Mitochondria are uninvolved in processes related to cell signaling.

The tissue surrounding the granuloma in an immune cell induces an inflammatory immune response.


Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Incidence rates of cervical cancer have increased over time.

Bromodomain proteins promote the differentiation process of bloodstream form (BSF) to procyclic form (PCF) parasites.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

Short British students are bullied more than control British students.

Genetic deletion of JAM-A decreases gut permeability.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

All phenotypes associated with reduced IIS require the gene daf-16.

CENP-B inhibits heterochromatin formation

Pyridostatin delays checkpoint activation.

The innate immune response is efficient at removing small numbers of parasites.


Impaired RhoA activity causes megakaryocytes to exit mitosis without complete karyokinesis

The ring complexes of chromosomes in C. elegans oocytes are built in discrete layers.

Allele and genotype frequencies of the rs4516035 and rs2298850 SNPs in Mexican populations are associated with region in Mexico.

Immune complex triggered cell death leads to extracellular release of oxidized mitochondrial DNA.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of atopic eczema at 1 year.

S-nitrosylated GAPDH physiologically transnitrosylates target nuclear proteins.

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

The number of Ndc80 complexes varies with cell cycle timing.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

During the primary early antibody response activated B cells express high levels of EBI2.

Mitochondria play a major role in calcium homeostasis.

Cyclin A2 synthesis is necessary to switch from unstable to stable kt-mt attachments in mitosis.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

The number of unfertilized oocytes in mated hermaphrodites decreases with age.


In a naive state, blocking Wingless-Int-1 secretion from mouse embryonic stem cells encourages self-renewal of the mouse embryonic stem cells.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Unlike transposon mutagenesis, chemical mutagenesis has the capability to induce point mutations that are not typically modeled by insertional mutagenesis approaches.

Having a main partner increases survival rates in HIV patients.

A breast cancer patient's capacity to metabolize tamoxifen has no effect on treatment outcome.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

DUSP4 downregulation activates the Ras-ERK pathway

Genetic deletion of JAM-A decreases gut permeability.

CENP-B inhibits heterochromatin formation

Lmna knock-in models are not suitable to test therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Replacement of OCT4 and SOX2 genes with mesendoderm-related genes has the ability to reprogram human cells.

p53 controls autophagy through the AMPK/mTOR-dependent pathway.

Differentiated E2f-1, -2, -3 TKO cells in the intestine can exhibit apoptosis.

c-MYC is important for maintaining pluripotent state of pluripotent stem cells.

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

The balance between F- and G-actin regulates the orientation of neuronal migration in the developing cerebral cortex.


In pediatric tissues, the dominant population of T cells are naive T cells emigrants from the thymus.

Lithium damages function in the SCA1 mouse model

Oral ibandronate reduces relative risk of new vertebral fractures and clinical vertebral fractures in women.

Forkhead 0 (fox0) transcription factors are involved in cell cycle arrest.

Autophagy deficiency in the liver protects from insulin resistance.

Somatic missense mutations in NT5C2 are associated with relapse of acute lymphoblastic leukemia.

Gastric lavage shows no benefit for acute paraquat poisoning.

Synaptic activity impairs local release of brain derived neurotrophic factor from postsynaptic dendrites.

Synaptic activity impairs local synthesis of brain derived neurotrophic factor from postsynaptic dendrites.

Long-term use of statins showed a increased risk of gallstones followed by cholecystectomy.

Genetic deficiency of mast cells leads to increased weight gain in a mouse model of diet-induced obesity.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of European origin.

Approximately 22,500 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

T regulatory cells (tTregs) lacking αvβ8 are unable to suppress pathogenic T-cell responses during active inflammation.

Golli-deficient T-cells are dormant in initial clonal expansion.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

IL-10 production by monocytes encourages CD4 + T cell response.

Lice attenuated SIV vaccines induce a weaker antigen-specific T cell response in lymph node cells.

T cell receptor /CD3 microdomains are unnecessary in the induction of the immunlogical synapse.

There are no known genetic variants associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.


In rhesus macaques, daily subcutaneous injections of emtricitabine protect against rectally transmitted simian-human immunodeficiency virus.

Lupus-prone mice infected with curliproducing bacteria have lower autoantibody titers compared to controls.

Sweet taste receptors on the tongue are activated by between 300 and 1000 mM glucose.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

DUSP4 downregulation activates the Ras-ERK pathway

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Incidence of sepsis has remained stable between 2009-2014.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

Expression of MSX2 is induced 3 hours after the addition of BMP4, which occurs later than T and CDX2.

Chikungunya virus (CHIKV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in mice.

Mice are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Sustained transmission of Avian influenza A between humans is not observed.

AZT given with ribavirin alleviates anemia.

Vaccinating the gastrointestinal tract is not effective in protecting rectal and vaginal mucosa.

Combination nicotine replacement therapies with varenicline or bupropion are not associated with significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Long chain polyunsaturated fatty acids supplementation is associated with lower rates of allergic sensitization  at 1 year.


In the UK, drowning affects boys at a higher rate than girls.

Roughly 10% of women with chronic pelvic pain have no underlying pathology.

Roughly one in twenty UK citizens harbor variant Creutzfeldt-Jakob disease prions in lymphoid tissues.

Risedronate reduces risk of vertebral and non-vertebral fractures.

Golli-deficient T-cells are hyper proliferative in initial clonal expansion.

Deficiency of Tetraspanin-3 causes impaired stem cell-renewal and disease propagation.

Athletes with or without a concussion have smaller volumes of hippocampal gray matter compared to healthy controls.

Low saturated fat diets do not have adverse effects on growth or development of infants.

Autologous transplantation of mesenchymal stem cells has higher rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

For every 1,000 children with cerebral palsy, 40-150 of them are premature or underweight at birth.

Tuberculosis incidence is correlated with residential crowding in the UK.

Incidence rates of cervical cancer have increased over time.

The risk of cancer is lower in individuals with a history of heavy alcohol consumption.

Ninety percent (90%) of kidney cancers in the UK are attributable to excess weight.

Female carriers of the Apolipoprotein E4 (APOE4) allele have a reduced risk for Alzheimer's disease.

The proportion of people with visual difficulty is two times higher in high-income countries than in low-income countries.

Hypoglycemia decreases the risk of dementia.


Incidence of sepsis has remained stable between 2009-2014.

The H3.3K36me3 histone reader protein ZMYND11 has a  higher binding affinity if G34R/V is mutated.

De novo assembly of sequence data has longer contigs than unassembled sequence data.

Side effects associated with antidepressants decrease risk of stroke.

Bariatric surgery has a deleterious impact on mental health.

Hematopoietic progenitor cells are never susceptible to HIV-1 infection ex vivo.

Long chain polyunsaturated fatty acids supplementation is associated with higher rates of allergic sensitization  at 1 year.

Radiographic verified pneumonia predictions are improved by the combination of physical examinations with C-reactive protein values.

8% of burn patients are admitted for hospitalization and further treatment after appearing at hospital emergency wards or outpatient clinics.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

10-20% of people with severe mental disorder receive no treatment in low and middle income countries.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Participants who quit smoking reduce lung cancer risk by approximately 5%.

Asymptomatic bacteriuria has no effect on the risk for preterm delivery and low birth weight.

Some countries have achieved the goal of eradicting malaria.


Incidence rates of cervical cancer have increased over time.

Physical activity levels have been associated with the differences in VO2max between black and white youth.

Healthy volunteers exhibit rapid and transient decrease of cellular ATP after being bolus-injected with fructose.

The 7.5% 10-year Atherosclerotic cardiovascular disease risk threshold strategy for initiating statin therapy is less cost-effective than the 10% risk threshold strategy.

Adult tissue-resident macrophages possess a self-renewing capacity.

Thoracic aortic aneurysms affect 70-100 individuals per 100,000 people per year.

Genomic instability in leukemia cells results from an increase in reactive oxygen species from oncogene activation.

Mitochondria are uninvolved in processes related to cell signaling.

MEK inhibitors are not effective in RAS-driven mouse models of cancer.

Pseudoknots are evolutionarily conserved throughout most eukaryotes.

Primary cervical cytology screening with HPV detection is no more effective than conventional cytology at detecting severe cervical intraepithelial neoplasia.

In the UK, drowning affects boys at a higher rate than girls.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer


Increased calcium levels activate transgultaminase activity.

The phosphorylation of Drp1 at S616 site inhibits its mitochondrial translocation when activated by Ca 2+ /calmodulin-dependent kinase II (CaMKII).

Immune complex triggered cell death slows down extracellular release of nuclear DNA.

Cost effectiveness evaluations based on cRCT data do not represent patients in actual clinical practice.

All six cathelicidins are located on chromosome two.

G-CSF prevents MDSCs from infiltrating tumors.

High cardiopulmonary fitness causes decreased mortality rate.

Transplanted human glial progenitor cells can form a neural network with host animals' neurons.

Funding the elimination of sporadic malaria cases is a less efficient use of healthcare resources than treating other health priorities in a setting with limited resources.

Verbal autopsy (VA) performed well in distinguishing between different injury categories in the elderly population.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink more that non-carries.

Increased calcium levels repress transgultaminase activity.

Physical injury activates transgultaminase activity.

Inhibiting glucose-6-phospate dehydrogenase impairs lipogenesis by reactivating LKB1-AMPK signaling.

Autophagy deficiency in the liver protects from insulin resistance.

Osteocytes are not associated with G-CSF induced HSPC mobilization.

Mitochondria play a major role in calcium homeostasis.

GEF-H1 activates RhoA in response to extracellular signal-regulated kinase activation.

A deficiency of folate decreases blood levels of homocysteine.

Serotonin receptors play a role in depression


Increased calcium levels repress transgultaminase activity.

There are four spatial channels in each hemifield of the auditory cortex of cats.

Inside the body, falciparum parasites form agglomerates of infected cells to avoid spleen clearance.

No strong relationship has been found with Pioglitazone use and increased risk for pancreatic cancer

The myocardial cell lineage originally develops from cardiac progenitors of mesodermal origin.

Cytosolic proteins fail to bind to iron-responsive elements on mRNAs coding for TFRC1.

Increased expression of Bcl2 is important for the maintenance and progression of tumors.

C. elegans germlines lose their immortal character when nuclear RNAi is activated.

Antibiotic induced alterations in the gut microbiome increase resistance against Clostridium difficile

Nitric oxide (NO) can S- nitrosylate G protein-coupled receptor kinases (GRKs) to suppress their activity and block phosphorylation.

Serotonin receptors have no effect on depression