Transplanted human glial progenitor cells can mature in their host animal.

In chronic viral infections or tumors, peptides that selectively inhibit PTPRS can be utilized to boost insufficient activity of pDCs.

Bacteriophagaes MS2 and Qβ are members of the Leviviridae.

Ten percent (10%) of kidney cancers in the UK are attributable to excess weight.

Stiff substrates inhibit mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

A high microerythrocyte count protects against severe anemia in homozygous alpha (+)- thalassemia trait subjects.

There is no known interaction between Pioneer factor OCT3/4 and major chromatin remodeling factors.

Persistor cells are one reason for incomplete responses to Tyrosine kinase inhibitor (TKI) therapy in cancer patients.

BiP is a general endoplasmic reticulum stress marker.

KRT17 modulates the expression of the transcriptional regulator AIRE in diseased epithelia.

Human embryonic stem cells have the capacity to give rise to differentiated progeny representative of all three embryonic germ layers.

Specialized functional cell types can be derived from human pluripotent stem cells.

Androgenetic haploid mouse embryonic stem cells (ESCs) can be derived and genetically manipulated in vitro.

Human embryonic stem cells give rise to cell types from the outer embryonic germ layer, but not the other two layers.

Human embryonic stem cells give rise to cell types from all three embryonic germ layers.

Autologous transplantation of mesenchymal stem cells has better graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Mouse models can be generated using "artificial spermatids."

Nuclear transfer from adult human fibroblasts to human oocytes can give rise to blastocysts containing expandable pluripotent cells.

Bone marrow cells don't contribute to adult macrophage compartments.


Treatment with a protein named FN impairs regenerative abilities of aged muscles.

Bone Marrow (BM) transplantation is used to treat acute myeloid leukemia (AML)

Post-transcriptional handling of mitochondrial transcripts occurs in mitochondrial RNA granules.

Reducing H3k4me3 methylation induces mouse epiblast stem cells to naive pluripotency efficiently.

Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in similar efficacy and better quality of life when compared with oxaliplatin-based chemotherapy in elderly patients.

Deletion of ATM and Rad3 related protein is not predictive of acute tissue loss.

YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis.

53% of perinatal mortality is due to low birth weight.

Pyridostatin reduces proliferation of homologous recombination - defective cells.

Immune complex triggered cell death leads to sequestration of oxidized mitochondrial DNA.

Measuring routine outcomes is more beneficial to clinical practice than assessing treatment adherence.

Treatment with a protein named FN restores regenerative abilities of aged muscles.

Physical activity does not improve cognitive function in individuals with Alzheimers.

Inhibiting focal adhesion formation increases the rate at which cells convert mechanical strain into inflammation and fibrosis.

Inhibiting focal adhesion formation enables cells to convert mechanical strain into eventual scarring.

Lack of FGF21 in mice leads to reduced lifespan.

Rotator cuff exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.

General exercise therapy is more effective than rotator cuff exercises in reducing pain and improving function of the shoulder.

Surgical treatment is not superior to non-surgical in treating adults with displaced fractures of the proximal humerus.

Lack of FGF21 in mice increases life expectancy.


Treatment with a protein named FN restores regenerative abilities of aged muscles.

The amount of publicly available DNA data doubles every 10 months.

In S. cerevisiae, the absence of RNA surveillance pathways reduces sensitivity to high iron conditions.

Varying expression levels of EBI2 affect the positioning and migration of B cells.

Egr2 regulates the homeostasis of B and T cells.

Specialized functional cell types can be derived from human pluripotent stem cells.

Vaccinating the gastrointestinal tract induces protection of rectal and vaginal mucosa.

Gpr124 suppresses BBB breakdown in mouse models of ischemic stroke.

Interleukin-18 plays an important role in the pathogenesis of atherosclerosis.

HIV trans-activator protein (TAT) effectively transports large and small molecules across cellular membranes into larger populations of neurons.

The most prevalent adverse events to Semaglutide are cardiovascular.

General exercise therapy is more effective than scapular stabilizer exercises in reducing pain and improving function of the shoulder.

Scapular stabilizer exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.


Treatment with the EC uptake inhibitor AM404 resulted in a dose-dependent decrease in the expression of immobility.

Lack of FGF21 in mice leads to reduced lifespan.

DMS3 protein enables Pol V transcription in vivo.

Medications to treat obesity do not have side effects.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have only a modest impact in reducing malaria transmission.

The deregulated and prolonged activation of monocytes has deleterious effects in chronic infectious conditions.

Intra-cerebroventricular infusion of amyloid-β oligomers increases expression of fibronectin type-III domain-containing protein 5 mRNA in mice hippocampi.

KRT17 modulates the expression of the transcriptional regulator AIRE in diseased epithelia.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes fibrosis.

Chronic HIV stimulation of B cells leads to the premature exhaustion of B cells.

Stroke patients with prior use of direct oral anticoagulants have a higher risk of in-hospital mortality than stroke patients with prior use of warfarin.

Taking anti-depresents is associated with a decrease in the Aβ level in the brain of experimental animals.

The most prevalent adverse events to Semaglutide are cardiovascular.

The most prevalent adverse events to Semaglutide are gastrointestinal.

ITAM phosphorylation allows for the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Activation of PPM1D enhances p53 function.

Alirocumab treatment reduces apo(a) fractional clearance rate.

C2 works synergistically with A-769662 to activate dephosphorylated AMPK.

HSCT-T dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before AMI.

p16INK4A degradation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).


Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK.

Destination container port throughput(CPT) is positively related to dengue virus (DENV-1) diffusion in air traffic shipments.

Gastric infection with Helicobacter pylori decreases risk of gastric cancer in humans.

Pharmacist attendance at ward rounds increases adverse events in wards.

Aged patients are less susceptible to ischaemia/reperfusion injury.

Incidence of 10/66 dementia is higher than the incidence of DSM-IV dementia.

Reduction of purity of cytoplasmic membranes isolated from overexpressors is indicated by stronger spots for OmpF in 2D BN-PAGE gels.

The RANK-RANK-Ligand (RANKL) pathway is involved in the development of Aire-expressing medullary thymic epithelial cells (mTECs).

ATM and Rad3 related protein have no role in sensing DNA damage.

HNF4A mutations are associated with macrosomia in infancy.

Ethanol stress increases the expression of PSP in bacteria.

Antiretroviral therapy increases rates of tuberculosis across a broad range of CD4 strata.

There was an estimated 30 million cases of pneumonia in young children worldwide in 2010.

Urbanization is an important risk factor related to the transmission of dengue fever.

Chlamydia trachomatis is most prevalent in the UK among individuals in their 50s and 60s.

Sepsis related mortality has risen from 2009 to 2014.

Incidence of sepsis has fallen substantially from 2009 to 2014.

Approximately 250,000 people are infected with human T-cell lymphotropic virus type 1 in the United Kingdom.

In the UK, drowning affects boys and girls equally.


Tuberculosis-induced granulomas express different immune system protein signatures than the surrounding tissue.

Rapid phosphotransfer rates are correlated with histidine kinase regulator specificity.

Antidepressants reduce the severity of migraines.

The predominant localization of Linc00173 is in mononuclear macrophage nuclei.

Increased purity of cytoplasmic membranes isolated from overexpressors is indicated by stronger spots for OmpF in 2D BN-PAGE gels.

Risk of cardiovascular events can be cut by a third by using antihypertensive drug therapy among hemodialysis patients.

Chinese individuals with TT homozygosity in the MTHFR gene are more vulnerable to strokes caused by low levels of folate intake.

The PPR MDA5 has twenty N-terminal CARD domains.

Klf4 is not required for proper myeloid cell differentiation.

Nuclear transfer from adult human fibroblasts to human oocytes can give rise to blastocysts containing expandable pluripotent cells.

miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription.

The tissue surrounding the granuloma in an immune cell induces an anti-inflammatory immune response.

Normal granulomas form in the presence of TNF in Zebrafish.

Normal granulomas form in the absence of TNF in Zebrafish.

Cancer-associated fibroblasts (CAFs) have no known interaction with cancer cells in the formation and activation of CAFs.

Glioblastoma multiforme (GBM) is characterized by extensive invasion, rapid growth, necrosis, and angiogenesis.

Mice are incapable of producing neutralizing antibodies in reponse to the Chikungunya virus (CHIKV) produced in mosquitos.

Cancer-associated fibroblasts (CAFs) interact with cancer cells to mediate formation and activation of CAFs.

The latent infection of myeloid cells with human cytomegalovirus induces a number of changes in gene expression.


Tumor development occurs in conjunction with suppression of pro-inflammatory cytokines.

taa1 tar1 tar2 triple mutants in Arabidopsis do not make root meristem during embryogenesis.

M. stadtmanae induces ASC speck formation in BlaER1 monocytes.

Helicobacter pylori-induced aberrant NF-kB-dependent expression of activation-induced cytidine deaminase contributes to the mutagenesis of host DNA.

Mice that lack Interferon-γ or its receptor are highly susceptible to experimental autoimmune myocarditis.

Tonic signaling from the scFv induces constitutive stimulation.

Systemic immunosuppressive (IS) therapy increases the chance of cancer mortality in patients with inflammatory eye disease (IED)

A 100g dose of chloroquine chemoprophylactic regimen results in retinal toxicity after 5-6 years of weekly intake.

Diabetes remission occurs less in people treated with conventional therapy than in people treated with laparoscopic adjustable gastric banding surgery.

AMP-activated protein kinase (AMPK) activation reduces inflammation-related fibrosis in the lungs.

Increase of p62 in prostate tumor stroma results in defective autophagy.

Tumor development occurs in conjunction with upregulation of pro-inflammatory cytokines.

Pro-inflammatory cytokines are up regulated during tumor development.

Pro-inflammatory cytokines are up repressed during tumor development.

Primary pro-inflammatory cytokines suppress secondary pro- and anti-inflammatory mediators.

Many cytokines that are produced by cancer cells also contribute to carcinogenesis.

Notch signaling occurs between tumor cells and stromal cells.

Cancer cells can stimulate the accumulation of intra-tumoural myeloid-derived suppressor cells by promoting granulocyte colony stimulating factor production.


Tumor development occurs in conjunction with upregulation of pro-inflammatory cytokines.

Trans-acting factors, such as lncRNAs, influence mRNA translation.

MUC1-C activates the NF-κB p65 signaling pathway by interacting with IκB kinase ß.

Commelina yellow mottle virus (ComYMV) has three typical badnavirus ORFs, capable of encoding proteins 23, 15, and 216 kD.

Increased conversion of PGE 2 to PPARy ligand 15-ket-PGE 2 causes accumulation of PGE.

Lamins are associated with nuclear membrane structure maintenance.

Depletion of T-helper 17 (Th17) cells during simian immunodeficiency virus (SIV) infection increases dissemination of Salmonella Typhimurium from the gut.

F4/80+ macrophages regulate mature osteoblast maintenance.

The minor G allele of FOXO3 downregulates pro-inflammatory cytokines.

Major antigen-induced signals from the T cell receptor and secondary signals from costimulatory receptors are required for T cell activation.

The most prevalent adverse events to Semaglutide are gastrointestinal.

The cytokine receptor which regulates chemotaxis and formation of lymph nodes is involved in production of myeloperoxidase in the left atrium.


Two variants of chromosome 6q21 are associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

Pharmacist attendance at ward rounds reduces adverse events in wards.

The ability of activator E2Fs in preventing cell death is limited to terminally differentiated cells.

The G34R/V mutation does not create a hypomethylated phenotype at the H3K36 histone.

Ultrasound guidance significantly reduces the number of traumatic procedures when attempting needle insertion.

Lysine histone demethylase inhibitor JIB 04 is inactive against KDM5A.

Helicobacter pylori-induced aberrant NF-kB-dependent expression of activation-induced cytidine deaminase contributes to the mutagenesis of host DNA.

Female carriers of the Apolipoprotein E4 (APOE4) allele have decreased risk for dementia.

mcm 5 s 2 U is required for proper decoding of NNR codons in eukaryotes.

Higher plasma levels of I-carnitine, when associated with trimethylamine N-oxide, are positively correlated with cardiovascular events in humans.

Forkhead 0 (fox0) transcription factors are involved in apoptosis.

IL-6 signaling plays a major role in atherosclerotic cardiovascular disease.

miR-142-5P is a temperature-sensitive microRNA (miRNA).

Interleukin-18 plays an important role in the pathogenesis of atherosclerosis.

61% of colorectal cancer patients are diagnosed with regional or distant metastases.

Repressing IL-18 has negative effects on atherosclerotic lesion composition and progression.

1-1% of colorectal cancer patients are diagnosed with regional or distant metastases.

Lack of FGF21 in mice leads to reduced lifespan.

Lack of FGF21 in mice increases life expectancy.

RAD52 is involved in break-induced DNA replication (BIR).


Type 1 Diabetes is associated with subtle perturbations in T reg development.

Autophagy deficiency in the liver increases vulnerability to insulin resistance.

YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis.

Forkhead 0 (fox0) transcription factors are involved in cellular differentiation.

Long chain polyunsaturated fatty acids supplementation has no significant effects on wheezing or asthma at 3 and 6 years.

Cost effectiveness evaluations based on cRCT data accurately reflect prices for patients in actual clinical practice.

Risedronate increases risk of vertebral and non-vertebral fractures.

MeCP2 influences the synaptic maturation of neurons.

Integrating classroom-based collaborative learning with Web-based collaborative learning offers the best class performance.

Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) fail to reveal increased sensitivity to ionizing radiation (IR).

Amitriptyline is an effective treatment for chronic tension-type headaches.

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with autoimmune diseases such as Type 1 Diabetes.

CD28 initiates tonic signaling in conventional T cells, which causes an exhaustion phenotype and limited efficiency.

Major antigen-induced signals from the T cell receptor and secondary signals from costimulatory receptors are required for T cell activation.

IL-10 production by monocytes inhibits CD4 + T cell response.

Peroxynitrite is required for induction of T cell tolerance.

Foxk2 regulates autophagy genes in muscle cells and fibroblast cells.

Egr2 regulates the homeostasis of B and T cells.

Foxp3 represses the expression of transcriptional regulators implicated in memory T cell development.

In pediatric tissue, most T cells are naive T cell emigrants from the thymus.


Ultrasound guidance significantly reduces the number of needle insertion attempts necessary for a given procedure.

Cnn1 recruitment varies with cell cycle timing.

Bacteriophagaes MS2 and Qβ are members of the Leviviridae.

British female students are bullied more than British male students.

Pioneer factor OCT3/4 interacts with major chromatin remodeling factors.

Ribosome-inactivating protein-2 (RIP-2) interacts with the p75 NTR death domain

Many transmembrane receptors transmit signals by long-range conformational changes in the association of alpha-helices across the plasma membrane.

MafA phosphorylation enhances its ubiquitination.

Chinese individuals with TT homozygosity in the MTHFR gene are more vulnerable to strokes caused by low levels of folate intake.

Deltex has no known interactions with eIF3f.

Medications to treat obesity have unwanted side effects.

Ultrasound guidance significantly reduces the number of traumatic procedures when attempting needle insertion.

Asymptomatic visual impairment screening in elderly populations leads to improved vision.

Primary cervical cytology screening with HPV detection has higher longitudinal sensitivity to detect severe cervical intraepithelial neoplasia than conventional cytology.

Measuring routine outcomes is more beneficial to clinical practice than assessing treatment adherence.

Flexible molecules experience less steric hindrance in the tumor microenviroment than rigid molecules.

Assessing treatment adherence is more beneficial to clinical practice than measuring routine outcomes.

The mean suicide rate in women is lower after miscarriage than live birth.

Including pharmacists in rounding teams reduces the incidence of adverse drug events (ADEs).

The mean suicide rate in women is higher after miscarriage than live birth.


Ultrasound guidance significantly reduces the number of traumatic procedures when attempting needle insertion.

Urbanization is an important risk factor related to the transmission of dengue fever.

During non-homologous end joining, the ligation step is not as tolerant of disrepairs and other distortions when joining 3' of strand breaks as compared to 5' strand breaks.

DRD1 proteins enable Pol V transcription in vivo.

Commelina yellow mottle virus (ComYMV) has three typical badnavirus ORFs, capable of encoding proteins 23, 15, and 216 kD.

Therapeutics receiving accelerated approval encounter a lower frequency of post-marketing safety events

Guanine nucleotide exchange factors (GEFs) mediate RhoA activation in response to tensional forces on fibronectin-binding integrins.

A country's Vaccine Alliance (GAVI) eligibility is not indictivate of accelerated adoption of the Hub vaccine.

1 in 5 million in UK have abnormal PrP positivity.

Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 prevents TDP-43-induced neuronal loss.

Surgical treatment is not superior to non-surgical in treating adults with displaced fractures of the proximal humerus.

Stroke patients with prior use of direct oral anticoagulants have a higher risk of in-hospital mortality than stroke patients with prior use of warfarin.

General exercise therapy is more effective than rotator cuff exercises in reducing pain and improving function of the shoulder.

Rotator cuff exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.

General exercise therapy is more effective than scapular stabilizer exercises in reducing pain and improving function of the shoulder.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are integral for recovery from spinal cord injury.

Scapular stabilizer exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.


Understanding epigenetic regulation of replication is essential for the reational design of episomally replicating vectors.

Mutations in RIM1 raise levels of IME1 RNA.

Hypothalamic glutamate neurotransmission is unrelated to energy balance.

Increase of p62 in prostate tumor stroma results in defective autophagy.

The DEXI promoter region is bound by multiple transcription factors in a murine haematopoietic progenitor cell line.

The PRDM1 gene is a key determinant of primordial germ cells.

Pharmacist attendance at ward rounds reduces adverse events in wards.

The cytokine receptor which regulates chemotaxis and formation of lymph nodes is involved in production of myeloperoxidase in the left atrium.

There was an estimated 30 million cases of pneumonia in young children worldwide in 2010.

The artifactual C-terminal helix swapping in the StART domain is observed in the Ups1-Mdm35 heterodimer of the StARkin superfamily.

At least 85% of patients exposed to radiation have activated markers of myofibroblasts.

Genes involved in pre-mRNA splicing have a significant impact on genome stability.

Cellular differentiation of embryonic stem cells is accompanied by changes in replication timing, transcription and nuclear localization.

Long - range chromatin interactions regulate transcription.

IFIT1 speeds viral replication by allowing for the proliferation of mis-capped viral RNAs.

RAD52 is involved in break-induced DNA replication (BIR).

Binding of p53 to enhancer regions (p53BERs) regulates the activity of p53 transcription and cell cycle arrest through the production of p53-dependent eRNAs.

Interferon stimulated genes (ISGs) Irf1, Irg1, Ifi27, and Rsad2 encourage West Nile virus replication in cortical neurons.

A strong bias in the phage genome locations where the spacers were derived has been observed in many CRISPR subtypes that confer the immunity to phage.

Increased mobility of retrotransposons does not lead to mutation and higher tumorigenesis rates.


Up-regulation of the p53 pathway and related molecular events speeds cancer progression.

Including pharmacists in rounding teams reduces the incidence of adverse drug events (ADEs).

Stiff substrates encourage mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes epithelial damage.

Glycan adaptation involves insertion-deletion events.

The most prevalent adverse events to Semaglutide are gastrointestinal.

The DESMOND program caused substantial weight loss in most participants.

10% of sudden infant death syndrome (SIDS) deaths happen in newborns aged less than 6 months.

In melanoma, anti-CTLA-4 treatment reinvigorates exhausted PD-1+Eomes+CD8 T cells.

Adult tissue-resident macrophages stem from the embryonal yolk sac and fetal liver.

Cancer-associated fibroblasts (CAFs) interact with cancer cells to mediate formation and activation of CAFs.

Activation of PPM1D enhances p53 function.

Many cytokines that are produced by cancer cells also contribute to carcinogenesis.

Cancer-associated fibroblasts (CAFs) have no known interaction with cancer cells in the formation and activation of CAFs.

Activated Cdk5 regulates DNA damage-induced neuronal death.

Cancers that initially benefit from epidermal growth factor receptor targeted therapies later become refractory through several mechanisms.

Tumor development occurs in conjunction with upregulation of pro-inflammatory cytokines.


Upon developing tyrosine-kinase inhibitor resistance, new mutations in epidermal growth factor receptors emerge and cause treatment failure.

IL-6 signaling plays a major role in atherosclerotic cardiovascular disease.

Urbanization is an important risk factor related to the transmission of dengue fever.

Many cytokines that are produced by cancer cells also contribute to carcinogenesis.

Omnivores produce more trimethylamine N-oxide from dietary I-carnitine than vegans.

Interferon stimulated genes (ISGs) Irf1, Irg1, Ifi27, and Rsad2 encourage West Nile virus replication in cortical neurons.

IL-10 production by monocytes inhibits CD4 + T cell response.

Origin gross domestic product(GDP) is negatively related to dengue virus (DENV-1) diffusion in air traffic shipments.

Transcription factor EB induces transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

Side effects associated with antidepressants do not represent a mortality risk to postmenopausal women.

Improvements in OER catalysts show stable activity over several hundred hours.

MEK inhibitors are effective treatments in RAS-driven mouse models of cancer.

Fibroblast Growth Factor is a ligand which signals through receptor tyrosine kinases.

Autophagy deficiency in the liver increases vulnerability to insulin resistance.

Monoclonal antibody targeting of N-cadherin inhibits growth.

Environmentally-induced senescence is mimicked in disease modeling by adding specific molecules to the culture system.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes fibrosis.

Cancer cells can stimulate the accumulation of intra-tumoural myeloid-derived suppressor cells by promoting granulocyte colony stimulating factor production.

The most prevalent adverse events to Semaglutide are cardiovascular.


Upon viral challenge, influenza-specific memory CD4+ T cells greatly diminish the early production of inflammatory chemokines in the lung.

Energy balance requires hypothalamic glutamate neurotransmission.

Cancer-associated fibroblasts (CAFs) interact with cancer cells to mediate formation and activation of CAFs.

In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, more than 50 percent of the cells with green florescent colocalize with cell proliferation markers.

Tirasemtiv has no effect on cardiac muscle.

Replacement of OCT4 and SOX2 genes with GATA3 is not capable of reprogramming human cells.

Mouse models can be generated using "artificial spermatids."

Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK.

Chlamydia trachomatis is most prevalent in the UK among individuals in their 50s and 60s.

Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung.

Enhanced early production of inflammatory chemokines damages viral control in the lung.

CD28 signals regulate trafficking of murine auto-reactive T cells into target tissues.

The latent infection of myeloid cells with human cytomegalovirus induces a number of changes in gene expression.

Transcription factor EB induces transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

CD28 initiates tonic signaling in conventional T cells, which causes an exhaustion phenotype and limited efficiency.

AMP-activated protein kinase (AMPK) activation reduces inflammation-related fibrosis in the lungs.

Mice that lack Interferon-γ or its receptor are highly susceptible to experimental autoimmune myocarditis.

Eilat virus (EILV) produced in mosquitos elicits rapid and long-lasting neutralizing antibodies in nonhuman primates.


Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung.

TNFAIP3 is a glioblastoma tumor suppressor.

Charcoal shows no benefit for acute paraquat poisoning.

Immune complex triggered cell death leads to sequestration of oxidized mitochondrial DNA.

The density of cytokine receptor bearing cells affects the distance over which cytokines act.

In rhesus macaques, daily subcutaneous injections of tenofovir protects against rectally transmitted simian-human immunodeficiency virus.

Angiotensin converting enzyme inhibitors are associated with decreased risk for functional renal insufficiency.

Kir7.1 modulates channel activity by the G protein-coupled melanocortin-4 receptor (MC4R) in the paraventricular nucleus of the hypothalamus.

Removal of H3K9me3 by ectopic expression of other H3K9 demethylases decreases reprogramming efficiency in SCNT experiments.

Pyridostatin decreases telomere fragility in BRCA2-deficient cells.

The number of unfertilized oocytes in mated hermaphrodites increases with age.

Tuberculosis-induced granulomas express different immune system protein signatures than the surrounding tissue.


Upregulation of PD1 causes the downmodulation of Satb1.

The DESMOND program caused substantial weight loss in most participants.

Individuals with low serum vitamin D concentrations have decreased risk of multiple sclerosis.

90% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Having a main partner improves HIV outcomes.

Pioglitazone use is significantly associated with an increased risk of prostate cancer.

IFI16 impedes STING phosphorylation and translocation, resulting in reduced activation of STING.

Activated Cdk5 phosphorylates the ATM protein in response to DNA damage.

Pioglitazone use is significantly associated with an increased risk of pancreatic cancer.

Antimicrobial agents are more effective due to the pressure of antimicrobial usage.

Upregulation of PD1 causes the upregulation of Satb1.

PD-1 triggering on monocytes enhances IL-10 production by monocytes.

Activation of PPM1D enhances p53 function.

Decrease of p62 in prostate tumor stroma results in defective autophagy.

Increase of p62 in prostate tumor stroma results in defective autophagy.

Inhibiting glucose-6-phospate dehydrogenase improves lipogenesis by deactivating LKB1-AMPK signaling.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes fibrosis.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes epithelial damage.


Upregulation of PD1 causes the upregulation of Satb1.

Birth-weight is negatively associated with breast cancer.

Genetic deficiency of mast cells leads to decreased weight gain in a mouse model of diet-induced obesity.

Pre-mRNAs associated with spliceosomal components are more stable than unassociated splicing substrates.

Localization of PIN1 in the roots of Arabidopsis requires VPS9a

NR5A2 is important in reverse cholesterol transport in humans.

In chronic viral infections or tumors, peptides that selectively inhibit PTPRS can be utilized to boost insufficient activity of pDCs.

Adult tissue-resident macrophages stem from the embryonal yolk sac and fetal liver.

aPKCz causes tumour suppression by affecting glutamine metabolism.


Upregulation of dynein in Drosophila neurons increases the number of microtubule plus-ends growing toward the cell body of each neuron.

ERAP1 SNPs are epistatic to HLA alleles for ankylosing spondylitis.

Higher plasma levels of I-carnitine, when associated with trimethylamine N-oxide, are negatively correlated with cardiovascular events in humans.

The morphology change from large white adipocytes to small brown adipocytes is a sign of decreased energy expenditure potential in white adipose tissue.

In rhesus macaques, daily subcutaneous injections of tenofovir protects against rectally transmitted simian-human immunodeficiency virus.

Pre-mRNAs associated with spliceosomal components are less stable than unassociated splicing substrates.

Reduced phosphorylation of PP2A increases HDAC4 dephosphorylation by enhancing PP2A-HDAC4 interaction.

Reducing H3k4me3 methylation induces mouse epiblast stem cells to naive pluripotency efficiently.

Comparative transcriptome analysis identified new platelet proteins with structural features suggesting a role in platelet function.

DMS3 protein enables Pol V transcription in vivo.

The proliferative capacity of neural progenitors differs across species.

Hypothalamic glutamate neurotransmission is unrelated to energy balance.

Mice lacking Sirt1 in Sf1-expressing neurons have increased susceptibility to diet-induced obesity and insulin resistance.

Guanine nucleotide exchange factors (GEFs) mediate RhoA activation in response to tensional forces on fibronectin-binding integrins.

Mice lacking Sirt1 in Sf1-expressing neurons are immune to diet-induced obesity and insulin resistance.

Energy balance requires hypothalamic glutamate neurotransmission.

HIV trans-activator protein (TAT) effectively transports large and small molecules across cellular membranes into larger populations of neurons.

The proliferative capacity of progenitors is regulated cell-autonomously.

MeCP2 influences the synaptic maturation of neurons.


Urbanization is an important risk factor related to the transmission of dengue fever.

Increased microtubule acetylation exacerbates LRRK2 Roc-COR domain mutation induced locomotor deficits.

Perigenital skin is not the primary site of HIV acquisition.

Bacterial meningitis can be diagnosed on the basis of positive cerebrospinal fluid (CSF) cultures.

Microcin J25 encourages nucleoside triphosphate (NTP) binding.

A mutation in HNF4A leads to an increased risk of diabetes by the age of 14 years.

Mutations in RIM1 decrease levels of IME1 RNA.

Foxp3 enables the expression of transcriptional regulators implicated in memory T cell development.

Oxidative phosphorylation is one of the primary glycometabolic pathways in cells.

Two variants of chromosome 6q21 are associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

A 100g dose of chloroquine chemoprophylactic regimen results in retinal toxicity after 1 year of weekly intake.

Rising temperatures caused by global warming increases risk of dengue fever transmission.

Rising temperatures caused by global warming lowers the risk of dengue fever transmission.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have only a modest impact in reducing malaria transmission.

Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK.

The World Health Organization's (WHO) data collection process is biased downward by unequal selection of larger outbreaks.

There was an estimated 30 million cases of pneumonia in young children worldwide in 2010.

Exposure to fine particulate air pollution is unrelated to anxiety prevalence.

The latent infection of myeloid cells with human cytomegalovirus induces a number of changes in gene expression.


V-9302 inhibits antitumor responses by decreasing cell death and oxidative stress.

IFIT1 speeds viral replication by allowing for the proliferation of mis-capped viral RNAs.

BiP is a general endoplasmic reticulum stress marker.

Walking in traffic areas in London did not improve lung function in elderly adults.

Rapid phosphotransfer rates are correlated with histidine kinase regulator specificity.

Rotator cuff exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.

Foxp3 represses the expression of transcriptional regulators implicated in memory T cell development.

GATA3 regulates self-renewal capacity in bone marrow hematopoietic stem cells.

Repressing IL-18 has negative effects on atherosclerotic lesion composition and progression.

Patients with common epithelial cancers  are more likely to have an emergency event as their first hospital admission if they live in resource-deprived areas.

Risedronate increases risk of vertebral and non-vertebral fractures.

Sildenafil worsens erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

PGE 2 suppresss intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

aPKCz causes tumour suppression by affecting glutamine metabolism.

Formation of N-terminal pyroglutamate by glutamine cyclase (GC) competes with NTAQ1 for Nt-Gln substrates.

MafA ubiquitination increases the recruitment of coavtivator P/CAF by MafA.

MafA ubiquitination decreases the recruitment of coavtivator P/CAF by MafA.

Chemical injury represses transglutaminase 2 activity.

B3-Galectin decreases cell resistance to tyrosine kinase inhibitors (TKIs) by engaging the alternate KRAS-RalB signaling complex downstream of EGFR.

Higher plasma levels of I-carnitine, when associated with trimethylamine N-oxide, are negatively correlated with cardiovascular events in humans.


Vaccinating the gastrointestinal tract induces protection of rectal and vaginal mucosa.

Diminished ovarian reserve is a reliable indicator of infertility in a non-infertile population.

Recognition of start codons depends on the translation initiation factor IF3.

Antidepressants reduce the severity of migraines.

The World Health Organization's (WHO) data collection process is biased downward by unequal selection of larger outbreaks.

Comparative transcriptome analysis identified new platelet proteins with structural features suggesting a role in platelet function.

Hematopoietic Stem Cell purification reaches purity rates above 90%.

Misunderstandings between doctors and patients can lead to non-adherence.

Individuals with Alzheimers who participate in six months of physical activity improve cognitive function for up to 18 months.

PrimPol degrades short DNA replication intermediates on the leading strand during DNA replication.

There is no relation between Erythromycin use and hypertrophic pyloric stenosis.

Oat tolerant coeliac patients may have oat specific inflammatory cells in their small bowel mucosa.

Enhanced early production of inflammatory chemokines damages viral control in the lung.

Noninvasive positive pressure ventilation is not predictive of acute respiratory failure after solid organ transplantation.

Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung.

The effect of Lipopolysaccharides on kidney barrier function is dependent on inflammation levels.

Upon viral challenge, influenza-specific memory CD4+ T cells greatly diminish the early production of inflammatory chemokines in the lung.

Primary pro-inflammatory cytokines suppress secondary pro- and anti-inflammatory mediators.

The most prevalent adverse events to Semaglutide are gastrointestinal.

The cytokine receptor which regulates chemotaxis and formation of lymph nodes is involved in production of myeloperoxidase in the left atrium.


Varenicline monotherapy is more effective after 26 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

Suboptimal nutrition is a leading cause of premature death

Charcoal shows no benefit for acute paraquat poisoning.

Cellular clocks are associated with mitosis timing in NIH 3T3 cells.

HAND2 methylation is a key step in early endometrial carcinogenesis.

Physical activity level is associated with the difference in maximal oxygen consumption between black and white youth.

Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegans.

Localization of PIN1 in the roots of Arabidopsis requires VPS9a

Cost effectiveness evaluations based on cRCT data lack external validity.

Microglia are an innate immune cell type of the peripheral nervous system.

Combination nicotine replacement therapies with varenicline or bupropion are more effective after 12 weeks of reatment compared to varenicline monotherapy.

Sildenafil worsens erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

Side effects associated with antidepressants increases risk of stroke.

Side effects associated with antidepressants do not represent a mortality risk to postmenopausal women.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have only a modest impact in reducing malaria transmission.

Stroke patients with prior use of direct oral anticoagulants have a higher risk of in-hospital mortality than stroke patients with prior use of warfarin.

Side effects associated with antidepressants lower risk of myocardial infarction.

The most prevalent adverse events to Semaglutide are cardiovascular.

Pioglitazone use is significantly associated with an increased risk of pancreatic cancer.


Varying expression levels of EBI2 affect the positioning and migration of B cells.

Addition of BMP4, activin A, CHIR99021, and SU504 to reprogramming fibroblasts generates, expands and maintains cardiovascular progenitor cells (CPCs)

Continued HHV-8 transmission among MSM in San Francisco may be explained by urogenital contact.

NAC destabilizes NO to increase the effect of contrast agents on renal functions.

Charcoal is an effective treatment for acute paraquat poisoning.

Human embryonic stem cells have the capacity to give rise to differentiated progeny representative of all three embryonic germ layers.

The gene daf-16, which encodes forkhead Box O (FOXO), is required for all phenotypes associated with reduced insulin/insulin-like growth factor (Igf) signaling.

FACT and other histone chaperone(s) compensate for Histone 2A (H2A)-histone 2B (H2B) dimer eviction during the histone exchange process.

Pyridostatin induces checkpoint activation.

1-1% of colorectal cancer patients are diagnosed with regional or distant metastases.

B cells go though plasmablast differentiation and antibody production by continuous expression of EBI2.

Egr2 regulates the homeostasis of B and T cells.

Egr3 regulates the homeostasis of B and T cells.

The composition of myosin-II isoform switches from the A isoform to the B isoform during hematopoietic differentiation.

EGR2 is important to myelination of the peripheral nervous system.

Neutrophils produce IL-1β in response to large particles.

Exhaustion of B cells contributes to poor Ab response in HIV-infected individuals.

Mutations in G-Beta protein GNB1 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway.


Venules have less significant tunica adventitia than arterioles.

Taxation of sugar-sweetened beverages reduced the incidence rate of type II diabetes in India.

β-sheet opening occurs during pleurotolysin pore formation.

H4 G94P proteins induce degradation of free histones via Rad53-dependent mechanisms.

Glucose restriction to 0.05% reduces RLS (replicative life span) by 20-40% in S. cerevisiae.

Pyridostatin stabilizes the G - quadruplex in the telomeric region.

Risk-adjusted mortality rates are similar in teaching and non-teaching hospitals.

Diabetic patients with acute coronary syndrome experience decreased short-term and long-term risk for bleeding events.

Mice defective for deoxyribonucleic acid (DNA) polymerase m (polm) reveal increased sensitivity to ionizing radiation (IR).

Bariatric surgery leads to positive outcomes in mental health.

Flexible molecules experience less steric hindrance in the tumor microenviroment than rigid molecules.

Increased vessel density along with a reduction in fibrosis improves the efficacy of chemotherapy treatments.

Stiff substrates encourage mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Stiff substrates inhibit mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Lamins are found within the inner layer of the nuclear membrane of all cells.

Inhibiting focal adhesion formation increases the rate at which cells convert mechanical strain into inflammation and fibrosis.

Osteoparthritis (OA) is characterized by degeneration of articular cartilage, joint edge, and subchondral bone hyperplasia.

Myelin sheaths are lipid-rich cellular structures.


VgrG (Tssl) protein punctures membranes by forming a spike at the tip of the tube apparatus.

Sympathetic nerve activity is elevated throughout normal pregnancy.

Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung.

Rapamycin increases the concentration of triacylglycerols in fruit flies.

Cholesterol loading induces KLF4 expression in VSMCs, resulting in the expression of pro-inflammatory cytokines.

The DESMOND program demonstrates no significant impact on biochemical outcomes.

Rapid phosphotransfer rates are correlated with histidine kinase regulator specificity.

Natriuretic peptides protect against diabetes.

In British Men, haplogroup I decreases risk of cardiovascular disease.

High levels of CRP lead to a higher risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Oxidative DNA damage activates STING signalling.

Intramembrane cleavage by signal peptide peptidase aids in the degradation of proteins with a complex membrane orientation.

Many transmembrane receptors transmit signals by long-range conformational changes in the association of alpha-helices across the plasma membrane.

The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) is decorated with VgrG and PAAR proteins.

Neutrophil extracellular trap (NET) antigens may contain the targeted autoantigens PR3 and MPO.

Ly49Q directs the organization of neutrophil polarization by regulating membrane raft functions.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to promote efficient motility along stromal surfaces.

Piezo1 channels are sensors for cell migration in epithelial cells.

Drosophila supracellular actomyosin structures are found at boundaries in wing imaginal discs.


Vitamin D deficiency effects birth weight.

Nigerian physicians constitue the largest component of sub-Saharan Africa-trained physicians in the United States.

Pre-mRNAs associated with spliceosomal components are more stable than unassociated splicing substrates.

Helminths interfere with immune system control of coinfections by microbial pathogens 16.

Deletion of ATM and Rad3 related protein leads to acute tissue loss.

eRNAs influence is linked to senescence, aging, and carcinogenesis.

British female students are bullied more than British male students.

Continued HHV-8 transmission among MSM in San Francisco may be explained by urogenital contact.

Lamins are found within the inner layer of the mitochondrial membrane of all cells.

Reducing H3k4me3 methylation induces mouse epiblast stem cells to naive pluripotency efficiently.

siRNA knockdown of A20 slows tumor progression in an in vivo murine xenograft model.

Vitamin D is an important factor in the relationship between calcium and parathyroid hormone.

Birth-weight is negatively associated with breast cancer.

A deficiency of vitamin B12 decreases blood levels of homocysteine.

Excess gestational weight gain is associated with obesity-related pregnancy outcomes.

40mg/day dosage of folic acid and 2mg/day dosage of vitamin B12 does not affect chronic kidney disease (CKD) progression.

53% of perinatal mortality is due to low birth weight.

A deficiency of folate increases blood levels of homocysteine.

The mean suicide rate in women is lower after miscarriage than live birth.

A deficiency of vitamin B6 decreases blood levels of homocysteine.


Vitamin D is an important factor in the relationship between calcium and parathyroid hormone.

Charcoal shows no benefit for acute paraquat poisoning.

BCL-2 activation antagonizes the apoptotic effects of c-Myc.

Overexpressing Cnp1 N-tail variants rescues the temperature-sensitive growth defect of scm3-139.

Gastric lavage is an effective treatment for acute paraquat poisoning.

Long chain polyunsaturated fatty acids supplementation has no significant effects on wheezing or asthma at 3 and 6 years.

Side effects associated with antidepressants lower risk of myocardial infarction.

Scapular stabilizer exercises are more effective than general exercise therapy in reducing pain and improving function of the shoulder.

Pioneer factor OCT3/4 interacts with major chromatin remodeling factors.

Nonhuman primates are incapable of producing neutralizing antibodies in reponse to the Eilat virus (EILV) produced in mosquitos.

Ethanol stress increases the expression of PSP in bacteria.

Intake of folic acid (FA) and vitamin B6 (VB6) increases levels of homocysteine.

Intake of folic acid (FA) and vitamin B6 (VB6) reduces levels of homocysteine.

Sildenafil worsens erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

LDL cholesterol has a causal role in the development of cardiovascular disease.


Walking in traffic areas in London did not improve lung function in elderly adults.

A deficiency of vitamin B6 decreases blood levels of homocysteine.

Pro-inflammatory cytokines are up repressed during tumor development.

Physical injury represses transgultaminase activity.

Aged patients are more susceptible to ischaemia/reperfusion injury.

Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK.

Mutations in RIM1 decrease levels of IME1 RNA.

Rhythmic expression of Cry1 translates directly into a circadian regulation of cAMP signaling in hepatic glucose metabolism.

Prescribed exercise training improves quality of life.

C2 works synergistically with A-769662 to activate dephosphorylated AMPK.

Varying expression levels of EBI2 affect the positioning and migration of B cells.

Walking in traffic areas in London improves lung function in elderly adults.

Participants who quit smoking reduce lung cancer risk by approximately 50%.

AMP-activated protein kinase (AMPK) activation reduces inflammation-related fibrosis in the lungs.

Nonhypertensive people who are 55 years old have a 90% chance of developing hypertension during their lifetime.

Exercise reduces cancer mortality rates among Chinese citizens.

Exercise increases cancer mortality rates among Chinese citizens.

Physical activity does not improve cognitive function in individuals with Alzheimers.

High levels of CRP lead to a higher risk of exacerbations in chronic obstructive pulmonary disease (COPD).


Walking in traffic areas in London improves lung function in elderly adults.

NAC destabilizes NO to increase the effect of contrast agents on renal functions.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) induces oxidative stress.

The PRDM1 gene, when combined with the PRDM14 gene, plays an important role during primordial germ cell specification.

r-protein chaperones are found in complexes with their r-protein binding partners.

Glioblastoma multiforme (GBM) is characterized by extensive invasion, rapid growth, necrosis, and angiogenesis.

Pyridostatin prevents double-strand breaks accumulation.

M. stadtmanae induces ASC speck formation in BlaER1 monocytes.

Taxation of sugar-sweetened beverages reduced the incidence rate of type II diabetes in India.

The C-type lectin receptor (CLEC-2) rearranges the actin cytoskeleton in dendritic cells to promote efficient motility along stromal surfaces.

H4 G94P proteins suppress degradation of free histones via Rad53-dependent mechanisms.

Physical activity level is associated with the difference in maximal oxygen consumption between black and white youth.


Weighed food records (WFR) result in high completion since they're cheap to run and impose low participant burden.

Low nucleosome occupancy correlates with high methylation levels across species.

Inhibiting focal adhesion formation increases the rate at which cells convert mechanical strain into inflammation and fibrosis.

Origin gross domestic product(GDP) is negatively related to dengue virus (DENV-1) diffusion in air traffic shipments.

Dscam1 acts as a hypervariable pattern-recognition receptor for the immune system.

90% of sudden infant death syndrome (SIDS) deaths happen in newborns aged less than 6 months.

Higher plasma levels of I-carnitine, when associated with trimethylamine N-oxide, are positively correlated with cardiovascular events in humans.

Exercise increases cancer mortality rates among Chinese citizens.

Certain immunomodulator-human dialyzable leukocyte extract (hDLE) peptides are recognized by toll-like receptors (TLRs) on macrophages and dendritic cells.

Monoclonal antibody targeting of N-cadherin inhibits castration resistance.

In domesticated populations of Saccharomyces cerevisiae, segmental aneuploidy is very common.

Weighed food records (WFR) result in poor completion since they're costly to run and impose high participant burden.

Cost effectiveness evaluations based on cRCT data lack external validity.

Cost effectiveness evaluations based on cRCT data accurately reflect prices for patients in actual clinical practice.

Including pharmacists in rounding teams does not alter the incidence of adverse drug events (ADEs).

Glucose restriction to 0.05% reduces RLS (replicative life span) by 20-40% in S. cerevisiae.

Including pharmacists in rounding teams reduces the incidence of adverse drug events (ADEs).

Polymeal nutrition increases cardiovascular mortality.

Measuring routine outcomes is more beneficial to clinical practice than assessing treatment adherence.

A country's Vaccine Alliance (GAVI) eligibility is not indictivate of accelerated adoption of the Hub vaccine.


Weighed food records (WFR) result in poor completion since they're costly to run and impose high participant burden.

Notch signaling occurs between tumor cells and stromal cells.

The removal of reactive oxygen species by activated oncogenes contributes to the increased genomic instability of leukaemia cells.

10% of sudden infant death syndrome (SIDS) deaths happen in newborns aged less than 6 months.

In British Men, haplogroup I increases risk of cardiovascular disease by 50%.

siRNA knockdown of A20 slows tumor progression in an in vivo murine xenograft model.

Nonsteroidal antinflammatory drugs are ineffective as cancer treatments.

Transcription factor EB induces transcription of pro-inflammatory cytokines in macrophages infected with Staphylococcus aureus.

Female carriers of the Apolipoprotein E4 (APOE4) allele have decreased risk for dementia.

HIV trans-activator protein (TAT) effectively transports large and small molecules across cellular membranes into larger populations of neurons.

Adult tissue-resident macrophages stem from the embryonal yolk sac and fetal liver.

Moderate consumption of candy and chocolate reduces the risk of cardiovascular disease (CVD).


Whole brain radiotherapy increases the occurrence of new brain metastases.

Ca2+ cycling is a UCP1-independent thermogenic mechanism.

7-day-old adult Caenorhabditis elegans exhibit approximately 75% of the learning capacity seen in 1-day old adults.

Pyridostatin prevents double-strand breaks accumulation.

Women with a lower birth weight are more likely to develop breast cancer later in life.

In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, more than 50 percent of the cells with green florescent colocalize with cell proliferation markers.

Helicobacter pylori-induced aberrant NF-kB-dependent expression of activation-induced cytidine deaminase contributes to the mutagenesis of host DNA.

Vaccinating the gastrointestinal tract induces protection of rectal and vaginal mucosa.

VgrG (Tssl) protein punctures membranes by forming a spike at the tip of the tube apparatus.

Exposure to fine particulate air pollution is unrelated to anxiety prevalence.

Foxp3 enables the expression of transcriptional regulators implicated in memory T cell development.

Genomic aberrations of metastases provide information for targeted therapy.

Antidepressants increase the severity of migraines.

At least 85% of patients exposed to radiation have activated markers of myofibroblasts.

Headaches are correlated with cognitive impairment.

Individuals with Alzheimers who participate in six months of physical activity improve cognitive function for up to 18 months.

G-CSF increases the expansion and infiltration of MDSCs into tumors.

Antidepressants reduce the severity of migraines.

In patients with congenital heart defects, β-blockers significantly improve clinical heart failure outcomes.


Women are more susceptible to death due to pneumonia when compared to men.

Continued HHV-8 transmission among MSM in San Francisco may be explained by urogenital contact.

Genetic deficiency of mast cells leads to decreased weight gain in a mouse model of diet-induced obesity.

Rising temperatures caused by global warming increases risk of dengue fever transmission.

Tumor development occurs in conjunction with suppression of pro-inflammatory cytokines.

M. stadtmanae induces ASC speck formation in BlaER1 monocytes.

Amitriptyline is an effective treatment for chronic tension-type headaches.

Understanding epigenetic regulation of replication is essential for the reational design of episomally replicating vectors.

siRNA knockdown of A20 slows tumor progression in an in vivo murine xenograft model.

Cognitive behavioral therapy is an ineffective treatment for insomnia

CD28 signals regulate trafficking of murine auto-reactive T cells into target tissues.

Men are more susceptible to death due to pneumonia when compared to women.

There was an estimated 30 million cases of pneumonia in young children worldwide in 2010.

The mean suicide rate in women is lower after miscarriage than live birth.

The mean suicide rate in women is higher after miscarriage than live birth.

Women with a lower birth weight are more likely to develop breast cancer later in life.

Bacterial meningitis can be diagnosed on the basis of positive cerebrospinal fluid (CSF) cultures.

Tuberculosis incidence occurs at higher rates in more sparsely populated areas in the UK.

Urbanization is an important risk factor related to the transmission of dengue fever.


Women with a lower birth weight are more likely to develop breast cancer later in life.

Side effects associated with antidepressants increases risk of stroke.

Ten percent (10%) of kidney cancers in the UK are attributable to excess weight.

ALDH1 expression is associated with poorer prognosis for breast cancer primary tumors.

PD-1 triggering on monocytes enhances IL-10 production by monocytes.

Perigenital skin is not the primary site of HIV acquisition.

There is no association between HNF4A mutations and diabetes risks.

General exercise therapy is more effective than rotator cuff exercises in reducing pain and improving function of the shoulder.

Immune responses in immune cells are geographically segregated.

90% of patients with melanoma and an objective response to PD-1 blockade will experience a progression in their melanoma.

Therapeutics receiving accelerated approval encounter a lower frequency of post-marketing safety events

The risk of breast cancer among parous women decreases with placental weight of pregnancies.

Birth-weight is negatively associated with breast cancer.

53% of perinatal mortality is due to low birth weight.

Excess gestational weight gain is associated with obesity-related pregnancy outcomes.

Female carriers of the Apolipoprotein E4 (APOE4) allele have shorter lifetime exposure to estrogen due to a decreased reproductive period.

Female carriers of the Apolipoprotein E4 (APOE4) allele have longer lifetime exposure to estrogen due to an increased reproductive period.


YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis.

Helminths interfere with immune system control of coinfections by microbial pathogens 16.

Occipital activation levels are associated with auditory spatial performance in parietal regions of the brain.

Decrease of p62 in prostate tumor stroma results in defective autophagy.

Bariatric surgery reduces postmenopausal breast cancer.

A mutation in HNF4A leads to an increased risk of diabetes by the age of 14 years.

Hypothalamic glutamate neurotransmission is unrelated to energy balance.

The first MBT repeat of the four malignant brain tumor (4MBT) domain of Drosophila's Sfmbt and of the orthologous mammalian L3MBTL2 is required for the interaction with the spacer region of Drosophila's Pleiohomeotic (Pho) or its human ortholog YY1.

The ability of activator E2Fs in preventing cell death is limited to terminally differentiated cells.

Vitamin D is an important factor in the relationship between calcium and parathyroid hormone.

MICAL redox enzymes regulate actin dynamics.

p16INK4A degradation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).

4-PBA treatment decreases endoplasmic reticulum stress in response to general endoplasmic reticulum stress markers.

Mutant mice lacking SVCT2 have severely reduced ascorbic acid levels in both brain and adrenals.

Noninvasive positive pressure ventilation is not predictive of acute respiratory failure after solid organ transplantation.

4-PBA treatment raises endoplasmic reticulum stress in response to general endoplasmic reticulum stress markers.

Gpr124 increases BBB breakdown in mouse models of ischemic stroke.

Gpr124 suppresses BBB breakdown in mouse models of ischemic stroke.

CHOP is a general endoplasmic reticulum stress marker.

Oat tolerant coeliac patients may have oat specific inflammatory cells in their small bowel mucosa.


aPKCz causes tumour suppression by affecting glutamine metabolism.

BRCA 1 mutation carriers' risk of breast and ovarian cancer depends on where the mutation is located.

Pyridostatin stabilizes the G - quadruplex in the telomeric region.

Diabetes remission occurs more in people treated with conventional therapy than in people treated with laparoscopic adjustable gastric banding surgery.

De novo assembly of sequence data has fewer specific contigs than unassembled sequence data.

DUSP4 downregulation deactivates the Ras-ERK pathway

Crossover hot spots are found within gene promoters in Saccharomyces cerevisiae.

Consumption of whole fruits increases the risk of type 2 diabetes.

Adult tissue-resident macrophages are seeded before birth.

Increased conversion of PGE 2 to PPARy ligand 15-ket-PGE 2 causes accumulation of PGE.

Sudden death can occur in patients with orthostatic hypertension without cardiac conduction abnormalities.

The M2-phenotype in brown adipose tissue macrophages increases brown adipose tissue thermogenic activity.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes fibrosis.

Knockout proximal tubule-specific deletion of the BMP receptor Alk3 causes epithelial damage.

Cancer cells can stimulate the accumulation of intra-tumoural myeloid-derived suppressor cells by promoting granulocyte colony stimulating factor production.

Reduced levels of lipolysis leads to higher P38 phosphorylation in adipose tissue.

Increased lipolysis leads to higher P38 phosphorylation in adipose tissue.

An M2-like phenotype in brown adipose tissue macrophages is quickly induced by cold exposure.

Inhibiting glucose-6-phospate dehydrogenase improves lipogenesis by deactivating LKB1-AMPK signaling.

Upregulation of PD1 causes the upregulation of Satb1.


cSMAC formation represses weak ligand signalling.

Pyridostatin decreases telomere fragility in BRCA2-deficient cells.

The mean suicide rate in women is higher after miscarriage than live birth.

The cytokine receptor which regulates chemotaxis and formation of lymph nodes is involved in production of myeloperoxidase in the left atrium.

MafA ubiquitination decreases the recruitment of coavtivator P/CAF by MafA.

KRT17 modulates the expression of the transcriptional regulator AIRE in diseased epithelia.

General exercise therapy is more effective than rotator cuff exercises in reducing pain and improving function of the shoulder.

Walking in traffic areas in London improves lung function in elderly adults.

Transplanted human glial progenitor cells can mature in their host animal.

MeCP2 influences the synaptic maturation of neurons.

Origin gross domestic product(GDP) is positively related to dengue virus (DENV-1) diffusion in air traffic shipments.

CD28 initiates tonic signaling in conventional T cells, which causes an exhaustion phenotype and limited efficiency.

Tonic signaling from the scFv induces constitutive stimulation.

Tonic signaling from the scFv prevents constitutive stimulation.

T cell receptor /CD3 microdomains are required to induce the immunologic synapse.

Osteocytes have an essential role in G-CSF induced HSPC mobilization.

CD28 signals regulate trafficking of murine auto-reactive T cells into target tissues.

G-CSF increases the expansion and infiltration of MDSCs into tumors.


eRNAs influence is linked to senescence, aging, and carcinogenesis.

Stiff substrates inhibit mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Differentiation of progenitor cells to myeloid cells is skewed upon activation of insulin signaling.

Deltex interacts with eIF3. There is no known interaction between Deltex and elF3

7-day-old adult Caenorhabditis elegans exhibit approximately 5% of the learning capacity seen in 1-day old adults.

Increased flux of microbial products provokes immune responses.

The deregulated and prolonged activation of monocytes improves inflammatory disease outcomes.

Certain immunomodulator-human dialyzable leukocyte extract (hDLE) peptides are recognized by toll-like receptors (TLRs) on macrophages and dendritic cells.

Albendazole is used to treat soil-transmitted helminths.

PTEN is a regulator for the transcriptional activity of SRF

Binding of p53 to enhancer regions (p53BERs) regulates the activity of p53 transcription and cell cycle arrest through the production of p53-dependent eRNAs.

NR5A2 does not play a role in development of endometrial tissues.

Rhythmic expression of Cry1 translates directly into a circadian regulation of cAMP signaling in gluconeogenesis.

Environmentally-induced senescence is mimicked in disease modeling by adding specific molecules to the culture system.

EGR2 is important to myelination of the peripheral nervous system.

Many cytokines that are produced by cancer cells also contribute to carcinogenesis.

Activated Cdk5 regulates DNA damage-induced neuronal death.

NR5A2 is important in reverse cholesterol transport in humans.

Active caspase-11 participate in regulating phagosome-lysosome fusion.


mcm 5 s 2 U is required for proper decoding of NNR codons in eukaryotes.

Deltex interacts with eIF3. There is no known interaction between Deltex and elF3

A 100g dose of chloroquine chemoprophylactic regimen results in retinal toxicity after 5-6 years of weekly intake.

1-1% of colorectal cancer patients are diagnosed with regional or distant metastases.

Incidence of heart failure increased by 10% in women since 1979.

There is a positive correlation between hip fractures and statin use.

Differentiated E2f-1, -2, -3 TKO cells in the intestine do not exhibit apoptosis.

Crossover hot spots are found within gene promoters in Saccharomyces cerevisiae.

Side effects associated with antidepressants lower risk of myocardial infarction.

BiP is a general endoplasmic reticulum stress marker.

Exhaustion of B cells contributes to poor Ab response in HIV-infected individuals.

Recognition of start codons depends on the translation initiation factor IF3.

R2D2 stops miRNA production by increasing the selectivity of Dcr2 for long dsRNA.

Pseudoknots are not evolutionarily conserved in most eukaryotes.

During non-homologous end joining, the ligation step is not as tolerant of disrepairs and other distortions when joining 5' of strand breaks as compared to 3' strand breaks.

During non-homologous end joining, the ligation step is not as tolerant of disrepairs and other distortions when joining 3' of strand breaks as compared to 5' strand breaks.

The PPR MDA5 has twenty N-terminal CARD domains.

The predominant localization of Linc00173 is in mononuclear macrophage nuclei.

Stacking is more stable when a purine is present in the +5 position (C1698).


miR-142-5P is a known regulator of raised body temperature.

Lamins are found within the inner layer of the nuclear membrane of all cells.

Formation of N-terminal pyroglutamate by glutamine cyclase (GC) competes with NTAQ1 for Nt-Gln substrates.

Genomic aberrations of metastases provide information for targeted therapy.

Tonic signaling from the scFv is amplified by MyD88/CD40.

The artifactual C-terminal helix swapping in the StART domain is observed in the Ups1-Mdm35 heterodimer of the StARkin superfamily.

Adult tissue-resident macrophages are seeded before birth.

ScPif1p has reduced binding ability to G-rich ssDNA compared to non-G-rich ssDNA.

Genes involved in pre-mRNA splicing have a significant impact on genome stability.

Major antigen-induced signals from the T cell receptor and secondary signals from costimulatory receptors are required for T cell activation.

miR-142-5P is a temperature-sensitive microRNA (miRNA).

miRNAs regulate a unique suite of mRNAs to maintain homeostasis in cells.

Low expression of miR7a does not repress target genes or exert a biological function in ovaries.

miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription.

Low expression of miR7a does not repress target genes or exert a biological function in testis.

Ly49Q directs the organization of neutrophil polarization by regulating membrane raft functions.

The PRDM1 gene, when combined with the PRDM14 gene, plays an important role during primordial germ cell specification.

Overexpressing Cnp1 N-tail variants exacerbates the temperature-sensitive growth defect of scm3-139.

Ethanol stress lowers the expression of PSP in bacteria.


miR-142-5P is a temperature-sensitive microRNA (miRNA).

Antimicrobial agents are less effective due to the pressure of antimicrobial usage.

p16INK4A degradation is encoded by CDKN2A.

Higher plasma levels of I-carnitine, when associated with trimethylamine N-oxide, are negatively correlated with cardiovascular events in humans.

The appearance of brown-like or beige cells primarily occurs in visceral fat, not subcutaneous fat.

Replacement of OCT4 and SOX2 genes with GATA3 is not capable of reprogramming human cells.

The G34R/V mutation creates a hypomethylated phenotype at the H3K36 histone.

Antidepressants increase the severity of migraines.

The mean suicide rate in women is lower after miscarriage than live birth.

Repressing IL-18 has negative effects on atherosclerotic lesion composition and progression.

Microglia are an innate immune cell type of the peripheral nervous system.

TNFAIP3 is a glioblastoma tumor suppressor.

Microglia are an innate immune cell type of the central nervous system.

R2D2 stops miRNA production by increasing the selectivity of Dcr2 for long dsRNA.


miRNAs enforce homeostasis by suppressing low-level ''leaky'' transcription.

Low nucleosome occupancy correlates with high methylation levels across species.

A high microerythrocyte count protects against severe anemia in homozygous alpha (+)- thalassemia trait subjects.

HNF4A mutations are associated with macrosomia in infancy.

Genes regulated by Esrrb transcription factor are sensitive to Mbd3 function.

Progerin induces premature aging in stem cells.

NAC inhibits the generation of angiotensin-converting enzyme.

Rising temperatures caused by global warming lowers the risk of dengue fever transmission.

Bariatric surgery reduces postmenopausal breast cancer.

Antimicrobial agents are less effective due to the pressure of antimicrobial usage.

Genes involved in pre-mRNA splicing have a significant impact on genome stability.

Long - range chromatin interactions regulate transcription.

Trans-acting factors, such as lncRNAs, influence mRNA translation.


miRNAs regulate a unique suite of mRNAs to maintain homeostasis in cells.

Induced hepatic stem cells possess the potential to differentiate into cholangiocytic cells.

Two variants of chromosome 6q21 are associated with radiation therapy-induced second malignancies in pediatric Hodgkin lymphoma patients.

British female students are bullied more than British male students.

Physical activity level has no association with the difference in maximal oxygen consumption between black and white youth.

Mice defective for deoxyribonucleic acid (DNA) polymerase m (polm) fail to reveal increased sensitivity to ionizing radiation (IR).

Cardiac tissue-resident macrophages directly contribute to electrical activity.

Charcoal shows no benefit for acute paraquat poisoning.

Bariatric surgery leads to negative outcomes in mental health.

Normal expression of RUNX1 causes tumorsupressing effects.

The combination of physical examinations with C-reactive protein values do not improve the accuracy of radiographic verified pneumonia predictions.

Lamins are found within the inner layer of the mitochondrial membrane of all cells.

miR-142-5P is a known regulator of raised body temperature.


p16INK4A degradation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).

Differentiated E2f-1, -2, -3 TKO cells in the intestine do not exhibit apoptosis.

One in two surgical randomized controlled trials are discontinued early.

Exposure to fine particulate air pollution is unrelated to anxiety prevalence.

In rhesus macaques, daily subcutaneous injections of tenofovir protects against rectally transmitted simian-human immunodeficiency virus.

Immune complex triggered cell death leads to sequestration of oxidized mitochondrial DNA.

In British Men, haplogroup I increases risk of cardiovascular disease by 50%.

Phase information is useful for predicting donor-recipient matches in organ transplantation.

ATM and Rad3 related protein have no role in sensing DNA damage.

Origin gross domestic product(GDP) is negatively related to dengue virus (DENV-1) diffusion in air traffic shipments.

CD28 signals regulate trafficking of murine auto-reactive T cells into target tissues.

p16INK4A degradation is encoded by CDKN2A.

CDK6 shows impaired binding to loss-of-function variants of p18 INK4C.

Repressing IL-18 has negative effects on atherosclerotic lesion composition and progression.

CDK6 shows improved binding to loss-of-function variants of p18 INK4C.

Mutations in RIM1 decrease levels of IME1 RNA.

Gpr124 suppresses BBB breakdown in mouse models of ischemic stroke.

Reduced phosphorylation of PP2A increases HDAC4 dephosphorylation by enhancing PP2A-HDAC4 interaction.

The NF-κB essential modulator gene induces intestinal inflammation by promoting receptor-interacting protein (RIP) kinase 1 kinase activity-mediated epithelial cell death.

Interleukin-18 plays an important role in the pathogenesis of atherosclerosis.


p16INK4A degradation is encoded by CDKN2A.

Aged patients are more susceptible to ischaemia/reperfusion injury.

A diminished ovarian reserve is a very strong indicator of infertility, even in an a priori non-infertile population.

Omnivores produce more trimethylamine N-oxide from dietary I-carnitine than vegans.

Induced hepatic stem cells possess the potential to differentiate into hepatocytic cells.

Pure neural progenitor cell (NPC) populations can only be obtained from cell cultures that undergo passaging, filtration, or other isolation and cell sorting methods.

The peak incidence of fractures occurs in toddlers.

There is no association between HNF4A mutations and diabetes risks.

Broadly HIV-1 Neutralizing Antibodies (bnAb) 10EB have no affinity for phospholipids.

B cells go though plasmablast differentiation and antibody production by continuous expression of EBI2.

Self-advocacy training is effective at decreasing homelessness.

Activation of PPM1D enhances p53 function.

Reduced phosphorylation of PP2A suppresses HDAC4 dephosphorylation.

NR5A2 is important in reverse cholesterol transport in humans.

MUC1-C activates the NF-κB p65 signaling pathway by interacting with IκB kinase ß.


p75 NTR - associated cell death executor (NADE) interacts with the p75 NTR death domain

Nigerian physicians constitue the largest component of sub-Saharan Africa-trained physicians in the United States.

Cancer cells can stimulate the accumulation of intra-tumoural myeloid-derived suppressor cells by promoting granulocyte colony stimulating factor production.

GATA3 regulates self-renewal capacity in bone marrow hematopoietic stem cells.

ART has no effect on the infectiveness of HIV-positive people.

Therapeutics receiving accelerated approval encounter a lower frequency of post-marketing safety events

Reduced levels of lipolysis leads to higher P38 phosphorylation in adipose tissue.

Intake of folic acid (FA) and vitamin B6 (VB6) reduces levels of homocysteine.

Venules have less significant tunica adventitia than arterioles.

Myelin sheaths are lipid-rich cellular structures.

In breast cancer, the loss of myoepithelial cells promotes the transition of ductal carcinoma in situ to invasive carcinoma.

Ribosome-inactivating protein-2 (RIP-2) interacts with the p75 NTR death domain

Guanine nucleotide dissociation inhibitor (Rho-GDI) interacts with the p75 NTR death domain

Formation of N-terminal pyroglutamate by glutamine cyclase (GC) competes with NTAQ1 for Nt-Gln substrates.

Binding of p53 to enhancer regions (p53BERs) regulates the activity of p53 transcription and cell cycle arrest through the production of p53-dependent eRNAs.

ITAM phosphorylation allows for the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Replacement of histone H2A with H2A.Z accelerates gene activation in yeasts by destabilizing +1 nucleosomes.

Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 prevents TDP-43-induced neuronal loss.


qSOFA scores are associated with length of stay in emergency department patients.

At least 85% of patients exposed to radiation have activated markers of myofibroblasts.

Asymptomatic visual impairment screening in elderly populations leads to improved vision.

MT binding domain drives amyloid structure formation.

IL-6 signaling plays a major role in atherosclerotic cardiovascular disease.

Whole brain radiotherapy increases the occurrence of new brain metastases.

cSMAC formation represses weak ligand signalling.

The NF-κB essential modulator gene prevents intestinal inflammation by inhibiting receptor-interacting protein (RIP) kinase 1 kinase activity-mediated epithelial cell death.

Lmna knock-in models are appropriate for testing therapeutic approaches against Hutchinson-Gilford progeria syndrome (HGPS).

Bacterial meningitis can be diagnosed on the basis of positive cerebrospinal fluid (CSF) cultures.

GATA3 regulates self-renewal capacity in bone marrow hematopoietic stem cells.

Cost effectiveness evaluations based on cRCT data accurately reflect prices for patients in actual clinical practice.

TNFAIP3 is a glioblastoma tumor enhancer.

Including pharmacists in rounding teams does not alter the incidence of adverse drug events (ADEs).

TNFAIP3 is a glioblastoma tumor suppressor.

TNFAIP3 is a tumor enhancer in glioblastoma.

Increased diastolic blood pressure (DBP) is associated with abdominal aortic aneurysm.

Decreased diastolic blood pressure (DBP) is associated with abdominal aortic aneurysm.

Including pharmacists in rounding teams reduces the incidence of adverse drug events (ADEs).

Cost effectiveness evaluations based on cRCT data lack external validity.


r-protein chaperones are found in complexes with their r-protein binding partners.

Fibroblast growth factor 21 protects against atherosclerosis by modulating adiponectin and SREBP2 levels.

Cancers that initially benefit from epidermal growth factor receptor targeted therapies later become refractory through several mechanisms.

Increased LDL receptors plays a role in the reduction of plasma Lp(a).

Integrated care is successful at tackling multiple comorbidities.

Patients in stable partnerships progress from HIV to death at the same rate as patients not in partnerships.

Physical activity does not improve cognitive function in individuals with Alzheimers.

The appearance of brown-like or beige cells primarily occurs in visceral fat, not subcutaneous fat.

AZT given with ribavirin increases anemia.

Progerin induces premature aging in stem cells.

Ribosomopathies have a high degree of cell and tissue specific pathology.

Sequence conservation in gene regulatory regions between species is a high-accuracy predictor of conserved functionality.

Sequence conservation in gene regulatory regions between species is a poor predictor of conserved functionality.

Intramembrane cleavage by signal peptide peptidase aids in the degradation of proteins with a complex membrane orientation.

Many transmembrane receptors transmit signals by long-range conformational changes in the association of alpha-helices across the plasma membrane.

miRNAs regulate a unique suite of mRNAs to maintain homeostasis in cells.

Pre-mRNAs associated with spliceosomal components are more stable than unassociated splicing substrates.

Pre-mRNAs associated with spliceosomal components are less stable than unassociated splicing substrates.

mcm 5 s 2 U is required for proper decoding of NNR codons in eukaryotes.


siRNA knockdown of A20 accelerates tumor progression in an in vivo murine xenograft model.

Natriuretic peptides increase susceptibility to diabetes.

Autologous transplantation of mesenchymal stem cells has better graft function than induction therapy with anti-interleukin-2 receptor antibodies.

Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegans.

Antidepressants increase the severity of migraines.

Insulin effects appetite via ventral tegmental neurons.

Gastric infection with Helicobacter pylori decreases risk of gastric cancer in humans.

MICAL redox enzymes regulate actin dynamics in many cell types.

During non-homologous end joining, the ligation step is not as tolerant of disrepairs and other distortions when joining 5' of strand breaks as compared to 3' strand breaks.

B cells go though plasmablast differentiation and antibody production by continuous expression of EBI2.

siRNA knockdown of A20 slows tumor progression in an in vivo murine xenograft model.

Up-regulation of the p53 pathway and related molecular events speeds cancer progression.

TNFAIP3 is a glioblastoma tumor suppressor.

Low expression of miR7a does not repress target genes or exert a biological function in ovaries.

TNFAIP3 is a tumor enhancer in glioblastoma.

TNFAIP3 is a glioblastoma tumor enhancer.

Increased mobility of retrotransposons is assosciated with mutation and higher tumorigenesis rates.

Increased mobility of retrotransposons does not lead to mutation and higher tumorigenesis rates.

Increase of p62 in prostate tumor stroma results in defective autophagy.


siRNA knockdown of A20 slows tumor progression in an in vivo murine xenograft model.

Low expression of miR7a does not repress target genes or exert a biological function in ovaries.

Upon viral challenge, influenza-specific memory CD4+ T cells greatly enhance the early production of inflammatory chemokines in the lung.

In chronic viral infections or tumors, peptides that selectively inhibit PTPRS can be utilized to boost insufficient activity of pDCs.

Roughly 55% of women with chronic pelvic pain have no underlying pathology.

De novo assembly of sequence data has shorter contigs than unassembled sequence data.

Depletion of T-helper 17 (Th17) cells during simian immunodeficiency virus (SIV) infection increases dissemination of Salmonella Typhimurium from the gut.

The generation of reactive oxygen species by activated oncogenes contributes to the increased genomic instability of leukaemia cells.

Carriers of HNF4A mutations are at reduced risk for diabetes.

Pseudogene PTENP1 encodes a transcript that regulates PTEN expression.

L3MBTL2 binds to H2AK119Ub marked chromatin to form a PRC1 complex.

ALDH1 expression is associated with poorer prognosis for breast cancer primary tumors.

Low expression of miR7a does not repress target genes or exert a biological function in testis.


taa1 tar1 tar2 triple mutants in Arabidopsis do not make root meristem during embryogenesis.

Depletion of nitric oxide is responsible for vasospasm.

Risedronate increases risk of vertebral and non-vertebral fractures.

Helicobacter pylori-induced aberrant NF-kB-dependent expression of activation-induced cytidine deaminase contributes to the mutagenesis of host DNA.

The density of cytokine receptor bearing cells has no effect on the distance over which cytokines act.

ATM and Rad3 related protein are critical for sensing DNA damage.

Cell autonomous sex determination in somatic cells occurs in Galliformes.

Lysine histone demethylase inhibitor JIB 04 is inactive against KDM5A.

Propriospinal interneurons that play a role in the plastic reorganization of spinal circuits are integral for recovery from spinal cord injury.

Forkhead 0 (fox0) transcription factors are involved in cellular differentiation.

Localization of PIN1 in the roots of Arabidopsis requires VPS9a

Upregulation of PD1 causes the downmodulation of Satb1.

Removal of H3K9me3 by ectopic expression of other H3K9 demethylases improves reprogramming efficiency in SCNT experiments.

Removal of H3K9me3 by ectopic expression of other H3K9 demethylases decreases reprogramming efficiency in SCNT experiments.

YAP/TAZ is required in intestinal regeneration in mouse models of ulcerative colitis.

MT binding domain drives amyloid structure formation.

Inhibiting HDAC6 increases survival of mice with ARID1A mutated tumors.

Activation of the Rac1 homolog CED-10 kills viable cells in SRGP-1 mutant Caenorhabditis elegans.

ERAP1 SNPs are epistatic to HLA alleles for ankylosing spondylitis.


β-sheet opening occurs during pleurotolysin pore formation.

Varenicline monotherapy is more effective after 26 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

Ultrasound guidance significantly reduces the number of traumatic procedures when attempting needle insertion.

Monoclonal antibody targeting of N-cadherin inhibits growth.

LSD1-positive promoters are associated with RNA polymerase II

Addition of BMP4, activin A, CHIR99021, and SU504 to reprogramming fibroblasts generates, expands and maintains cardiovascular progenitor cells (CPCs)

In chronic viral infections or tumors, peptides that selectively inhibit PTPRS can be utilized to boost insufficient activity of pDCs.

Assessing treatment adherence is more beneficial to clinical practice than measuring routine outcomes.

Environmentally-induced senescence is mimicked in disease modeling by adding specific molecules to the culture system.

Mutant mice lacking SVCT2 have severely reduced ascorbic acid levels in both brain and adrenals.

VgrG (Tssl) protein punctures membranes by forming a spike at the tip of the tube apparatus.

Stiff substrates encourage mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Stiff substrates inhibit mesodermal differentiation by degrading beta-catenin in an integrin-dependent manner.

Venules have less significant tunica adventitia than arterioles.

Intramembrane cleavage by signal peptide peptidase aids in the degradation of proteins with a complex membrane orientation.

The microtubule-dependent delivery and secretion of matrix metalloproteases (MMPs) is partially responsible for the disassembly of adhesion sites.

Myelin sheaths are lipid-rich cellular structures.

The tissue surrounding the granuloma in an immune cell induces an anti-inflammatory immune response.


Vitamin D deficiency effects birth weight.

Tonic signaling from the scFv induces constitutive stimulation.

Antiretroviral therapy increases rates of tuberculosis across a broad range of CD4 strata.

A diminished ovarian reserve is a very strong indicator of infertility, even in an a priori non-infertile population.

F4/80+ macrophages regulate mature osteoblast maintenance.

Lack of FGF21 in mice leads to reduced lifespan.

The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) is decorated with VgrG and PAAR proteins.

In the UK, drowning affects boys and girls equally.

Women with a lower birth weight are more likely to develop breast cancer later in life.

Neutrophils produce IL-1β in response to large particles.

Increased purity of cytoplasmic membranes isolated from overexpressors is indicated by stronger spots for OmpF in 2D BN-PAGE gels.

Reduction of purity of cytoplasmic membranes isolated from overexpressors is indicated by stronger spots for OmpF in 2D BN-PAGE gels.

Flexible molecules experience less steric hindrance in the tumor microenviroment than rigid molecules.

Reduction of purity of cytoplasmic membranes isolated from overexpressors is indicated by stronger spots for OmpA in 2D BN-PAGE gels.

PrimPol generates short DNA replication intermediates on the leading strand during DNA replication.