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Benefits of I.V. Vitamin C from Dr. Thomas Levy
While researching thousands of articles over the last few years in the preparation of my latest book on vitamin C (Levy, 2002), interesting patterns began to emerge. Even though the effects of vitamin C on over 25 different infectious diseases and over 100 different toxins were examined, common mechanisms of action became apparent. This was especially significant to me since I had long wondered how a single chemical entity (ascorbate, or vitamin C) could have such dramatically positive clinical effects on such a wide array of completely unrelated chemical compounds and infectious agents. Quite literally, there seemed to be no exceptions to this vitamin C effect. Even if vitamin C did not cure a given infection or toxic state, it always helped resolve such a condition to some degree.
Dr. Albert Szent-Gyorgyi, the brilliant scientist who won the Nobel Prize in 1937 for his discovery of vitamin C, also advanced what I would call a true theory of life in two of his last publications. Szent-Gyorgyi (1978, 1980) asserted that energy exchange in the body can only occur when there is an imbalance of electrons among different molecules, assuring that electron flow must take place. Natural electron donators give up electrons to natural electron acceptors. Szent-Gyorgyi maintained that dead tissue had a full complement of electrons, a state in which no further exchange or flow of electrons could take place. Another way of viewing this is that brisk electron flow and interchange equals health, impaired or poor electron flow and interchange equals disease, and cessation of flow and interchange equals death. Vitamin C, as the premier antioxidant in the body, is perhaps the most important ongoing electron donor to keep this electron flow at optimal levels.
Oxidation involves the loss of electrons, and an antioxidant counters this process by supplying electrons. Although vitamin C is the most important antioxidant in the body, there are many different antioxidants present in the body, and many of them work to keep the more important antioxidant substances in the body in the reduced state, which allows the donation of electrons. For example, vitamin E is an antioxidant that is fat soluble, which is important in allowing it to be the primary antioxidant present in the lipid-rich cell membranes of the body. Vitamin C, which is water soluble, helps to recharge oxidized vitamin E in those cell membranes back to the electron-rich reduced form. Even though vitamin C is not the primary antioxidant in the cell wall, it plays a vital role in maintaining the optimal levels of the metabolically active antioxidant, vitamin E, at that site.
It appears, then, that the local loss of electrons (oxidation) represents the primary degeneration, or metabolic breakdown, of the tissue or chemical substance losing the electrons. An antioxidant can serve to immediately restore this loss of electrons, resulting in a prompt "repair" of that acutely oxidized tissue. Also, an antioxidant can often neutralize the oxidizing agent before it gets a chance to oxidize, or damage, the tissue initially.
All of the vitamin C/toxin exposure studies reviewed showed one or more of the following findings or consequences in the test tube, tissue, intact animal, or human studied:
1. Decreased levels of vitamin C and other antioxidants (blood and/or the tissues most specifically affected)
2. Increased levels of oxidative stress in the test setting, indicating ongoing oxidation
3. Increased liver production of vitamin C (in those species capable of this), as an adaptive response
4. Increased rates of consumption of vitamin C and other antioxidants
5. A direct correlation between toxin activity and antioxidant levels (lower antioxidant levels, greater clinical toxicity)
6. The acute induction of scurvy or other clinical findings consistent with the acute depletion of vitamin C
This entry was posted by homer on October 25, 2009 at 2:39 pm, and is filed under Minerals, Research. Follow any responses to this post through RSS 2.0. You can leave a response or trackback from your own site.
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A company is tax resident in Cyprus when its management and control is exercised in the Republic. Their taxable income includes both income earned in Cyprus and abroad. A non-Cyprus tax resident is taxed only on income earned through a permanent establishment in Cyprus.
(a) Corporation Tax
All companies are subject to a uniform tax rate of 10% except for semi-government organisations, which are taxed at 25%. The 10% tax is the lowest corporate tax rate in the European Union.
(b) Tax on Dividends
Cyprus tax-resident companies are exempt in respect of dividends received from other Cyprus resident companies. The exemption is extended, subject to conditions to dividends from non-resident companies. Resident companies are obligated to have distributed 70% of their after-tax profits in the form of dividends at the end of the two-year period since the end of the respective tax year.
Thereon, the dividends account for defence contribution in the case that less than 70% has been distributed. In this way, tax avoidance, through the accumulation of profits and the creation of companies by individuals as a means of lowering their tax burden, is prevented.
These mandatory distribution provisions do not apply to profits accruing to non-resident shareholders.
(c) Tax on Interest
Interest income is taxed at the corporate tax rate of 10% arising from, or closely connected to, the ordinary activities of the company.
Moreover, 50% of all other interest income is exempt from income tax and is subject to special defence contribution at 10%.
(d) Tax Treatment of Losses
Subject to certain conditions, tax losses can be carried forward and set off against future profits indefinitely; applicable for losses incurred in 1997 and thereafter. In addition, the loss of a Cyprus tax resident company can be set off against the profit of another Cyprus tax resident company in case they belong to the same group of companies. Subject to certain conditions, companies belong to a group when one company holds at least 75% of the ordinary share capital and the voting rights of another company. Losses from a permanent establishment abroad can be set off against profits earned by a company in Cyprus.
(e) Profits of Permanent Establishments Abroad
The profits of permanent establishments abroad are not subject to income tax in Cyprus, given that less than 50% of their activities result in investment income, and that the foreign tax suffered is not significantly lower than the tax payable in Cyprus.
(f) Disposal of Securities
Profits gained from the sale of securities listed on a recognised Stock Exchange are exempt from tax for all companies.
(g) Reorganisations
Transfers of assets and liabilities between companies in the course of reorganisations, such as mergers, demergers, transfer of activities or exchange of shares, are not subject to tax.
(h) Foreign Tax Credit
Tax relief of foreign tax paid is granted in Cyprus even in the absence of a double-taxation treaty, provided sufficient evidence is submitted that foreign tax was indeed paid. Hence, Cyprus turns into a lucrative hub for establishing holding companies.


Elder Scrolls 6 Confirmed, But There's Some Bad News
by : Ewan Moore on : 15 Jun 2016 14:33
skyrim-wall Forbes
Bethesda has announced that they're currently working on two massive games, similar in scope to Fallout 4 and Skyrim.
Unfortunately, while your mind might be racing with thoughts of The Elder Scrolls 6, Pete Hines, Vice President of PR and Marketing at Bethesda, told IGN that we won't be seeing that game for "many years".
skyrim-remaster
Bethesda's Todd Howard said during E3:
[Elder Scrolls 6 is] kind of like the elephant in the room, always, when we talk about anything, and you know, I think it's good in these moments to tell our fans yes, of course we are [working on it] – it's something we love – but it is… you know, I have to be careful what I say, it's a very long way off.
As a result, it seems Hines felt the need to elaborate and explain that they aren't keeping Elder Scrolls 6 out of reach to piss of the fans.
I'm just making sure folks understand, like, that doesn't mean he [Todd Howard] is going to spit out a DLC and another DLC and we're head faking. Like, I need folks to understand that we're talking about big games like a Skyrim and a Fallout 4 and a Fallout 3 and those don't just happen.
Screenshot-2016-06-12-23.34.41 DualShockers
Bethesda had a pretty strong showing at E3. They announced a completely reworked Prey 2, and a brand new Quake title.
They also showed of a lot more of Dishonored 2, shared some news on Fallout 4 DLC (plus a VR edition) and revealed a current gen remaster of Skyrim.
Regardless, fans are clearly hungry for an entirely new Elder Scrolls adventure, but it seems we'll be waiting for quite some time.
While it's still unclear what these other two mystery projects over at Bethesda will be, Howard promised that they're bigger than anything Bethesda has ever done, and that we'll hear more about them before we hear about Elder Scrolls 6.
Still, in the meantime we can look forward to the Skyrim remaster. It'll have all DLC and mod support, which should breathe some new life into the game (for console gamers at least).
Skyrim Special Edition will be coming to PS4, Xbox One, and PC October 28, while PC owners with the original game and all DLC can upgrade for free.
Ewan Moore
Ewan Moore is a journalist at UNILAD Gaming who still quite hasn't gotten out of his mid 00's emo phase. After graduating from the University of Portsmouth in 2015 with a BA in Journalism & Media Studies (thanks for asking), he went on to do some freelance words for various places, including Kotaku, Den of Geek, and TheSixthAxis, before landing a full time gig at UNILAD in 2016.
Topics: Gaming
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BETHESDA SAYS TWO UPCOMING GAMES ARE AS BIG AS SKYRIM AND FALLOUT
E3 2016: BETHESDA IS WORKING ON THE ELDER SCROLLS 6


Canmore and MD of Bighorn square off over Dead Man's Flats development
A battle is heating up between Canmore and the MD of Bighorn over a proposed development at Dead Man's Flats that's right next to a wildlife corridor and an underpass used by grizzlies, wolverines and elk.
Town is concerned the district wants to build light industrial near a wildlife corridor
CBC News · Posted: Jun 21, 2016 6:48 AM MT | Last Updated: June 21, 2016
Canmore Mayor John Borrowman says the MD of Bighorn needs to be cautious about developing in wildlife corridors. (CBC)
The MD of Bighorn wants to change the zoning on some of the land around the mountain hamlet to light industrial use, but neighbouring Canmore is opposed. The province is holding hearings on the dispute this week.
Wildlife advocates are unhappy with a plan for a light industrial development near this corridor in Dead Man's Flats. (CBC)
Canmore Mayor John Borrowman said there are a number of problems with development of the area — the animals may stop using the underpass and find unsafe places to cross the Trans Canada highway, or they may turn around and head back toward Canmore.
"And that's where safety issues arise, particularly the safety of humans, but also wildlife," he said.
Environment must be protected
The town filed an appeal against the changes through the Municipal Government Board, which adjudicates land planning and assessment matters.
Dead Man's Flats is a hamlet in the Rockies just east of Canmore.
He said both Canmore and the MD of Bighorn must develop responsibly.
"One of the important things to know is hundreds of hectares of developable land have already been given up in the town of Canmore for wildlife corridors and habitat patches," said Borrowman.
"So that's hundreds of millions of dollars' worth of land and future assessment, and we are just asking the MD to have the same perspective on the importance of protecting the environment and to find other options for their fiscal concerns."
Jodi Hilty is the chief scientist with the Yellowstone to Yukon Conservation Initiative and is worried about the long-term impacts if animals are unable to migrate.
"We think it's really, really important, not just for today but for future generations, if we are going to sustain vibrant populations in this region," she said.
MD lost tax revenue
Martin Buckley, chief administrative officer for the MD of Bighorn, previously told CBC News there are no immediate plans to develop the area, but the municipality has to keep its options open.
"We've lost some tax revenue as the result of the shutdown of a major gas plant up north, the flood has affected us as well. So it's a case of looking to the future for us," he said in November of last year.
Buckley also takes issue with the presumed impact of any development, and said there's no evidence the wildlife corridor would be impacted.
The MD of Bighorn says it won't be providing any other comments other than its submission to the Municipal Government Board. The hearing is expected to last all week.
MORE CALGARY NEWS | Calgary council takes first step in 2026 Olympic bid
MORE CALGARY NEWS | Calgary to end ban on backyard skateboard ramps
With files from the CBC's Colleen Underwood
Dead Man's Flats plan pits Canmore against MD of Bighorn
Dead Man's Flats development plan concerns wildlife advocates
Dead Man's Flats name change rejected


More LA Business Journal
Agoura Hills May Score Rams' Temporary HQ
By Stephanie Henkel
The Los Angeles Rams are looking to lease office space in Agoura Hills, which would serve as the team's temporary headquarters until its Inglewood stadium is completed in 2019.
The NFL franchise is currently in negotiations with Woodland Hills commercial realtor Realty Bancorp Equities to rent a 50,000-square-foot office at 29899 Agoura Road, according to the Acorn.
Rick Principe, chief executive of Westcord Commercial Real Estate Services in Westlake Village, announced that the Rams intended on leasing space in Agoura Hills during an economic forecast breakfast held at California Lutheran University on March 18.
Earlier this week, the former St. Louis team filed a proposal with the city of Thousand Oaks to build athletic facilities at Cal Lu, which would operate as the team's in-season practice site.
However, lease agreements for both the Cal Lu facilities and Agoura Hills' office have not been signed.
Deals that have been inked include the decision to make the Rams the home team for a 2018 game in China and its T.V. deal with HBO. The relocated team will be featured on the HBO hit-series "Hard Knocks," which will follow the Rams through its training camp experience, scheduled to take place at UC Irvine in August.
Rams Sign Deal to Move to Thousand Oaks
Rams Seek Green Pasture
Rams Look to Conejo Valley for Spring Camp Site
Conejo Leads Search for Rams' HQ
Rams to Build Practice Facility in Conejo Valley
Thousand Oaks Figures in Rams' Long-Term Plans
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SA Expert – Up To 45 000 Deaths And Three Years Of Lockdown
22 Apr 2020 by Jasmine Stone in Health, Lifestyle, South Africa
At Last, A Slight Decline In SA COVID-19 Cases
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SA Records 20k Deaths In One Week
[imagesource: Roger Sedres/ Gallo Images via Getty Images]
These days, it seems like everyone is an expert on how, why, and when to end the national lockdown.
Some people actually are experts, though, like Prof Shabir Madhi, of Wits University, who heads the public health subcommittee advising President Cyril Ramaphosa and his cabinet.
Speaking during a webinar yesterday, Madhi said that over the course of the next two or three years, South Africa can expect up to 45 000 deaths from COVID-19, and intermittent lockdowns that last for that same duration.
Reporting below via TimesLIVE:
Madhi said new information showed that between 50 and 80 times more people are infected than we thought, but they are asymptomatic. This, in turn, showed that the mortality rate would be lower than expected.
"The only information we had in the early days from China was that a vast majority would be symptomatic," Madhi said.
"Based on that modelling, we felt at least 120,000 would die in SA because of Covid-19."
Since then, studies in the US, China and Iceland have shown that at least 50% of infected people are asymptomatic and that "changes the numbers completely".
Madhi said the estimate of between 120,000 and 150,000 deaths has been revised to 45,000, "a huge jump down".
Those deaths, Madhi said, wouldn't take place "in a single wave", but would occur over during the entire period of intermittent lockdowns, during which various epidemics would break out.
Before you compare that death toll to the flu, read this, and then remember that the death toll Madhi cites is only that 'low' because of the actions we have taken, and will continue to take, to fight the spread of the virus.
The professor said the upcoming winter months will be the worst, and that rules round mass gatherings and physical distancing would need to remain in place.
He said the new information had "huge implications in terms of quantifying the number of infections" and also had implications for lockdown.
Lockdowns would need to be "strategically phased out", he said, adding that those most at risk – for example the elderly and people with pre-existing respiratory issues and diabetes – would need to continue isolating themselves even as others returned to work.
Those solutions above echo the solutions we touched on yesterday, as well as the idea that we will have repeated lockdowns going forward.
One of the central arguments to ending the lockdown as soon as is safe to do so revolves around the health of our economy, and the needs of many South Africans to get back to earning a living.
Economist Prof Danie Meyer laid out a number of economic scenarios two weeks ago, but the nature of the coronavirus is such that things can change in a matter of days.
Writing for Biznews, Clem Sunter, a scenario planner and strategist, has outlined four scenarios of what the near future could hold for South Africans.
Without going into too much detail, here are the first three.
All the medical flags which have gone up over the last month indicate that this scenario can almost certainly be discarded as a way of interpreting the past and the future of the pandemic.
The rise in the number of deaths by a factor of 55 in such a short period, and the fact that the public health systems of some of the richest nations on Earth have been completely overwhelmed, indicate the sheer scale and suddenness of the current disease.
The camel's straw
…the coronavirus does not have to kill millions of people to be the straw that breaks the camel's back.
The global economy was already vulnerable before the pandemic began, with slower economic growth in China and the ongoing trade spat between the two biggest economies in the world, America and China. All that was required, therefore, was a small disruption to make the global economy collapse like it did in the Great Depression of the 1930s.
Spain again
The third scenario of a repeat of the Spanish flu of the last century, which killed 3 to 5% of the world's population, will remain in play until a vaccine is found. As already indicated, the coronavirus is unlikely just to melt away even with prolonged restrictions on human movement.
His fourth scenario looks like it could be the most likely, and has been dubbed the tightrope:
…which is all about a delicate balancing act between preserving lives and livelihoods. The most important decision for any country to make is when and how to lift the restrictions in place by balancing the best medical models on the potential evolution of the pandemic against the need to revive the economy…
Furthermore, given that the spread of the virus has been uneven, different parts of a country may need different approaches and time lines…
As life begins to attain a new normal – it will never return to the old one – it will be up to businesses, families and individuals to walk the same tightrope in their daily activities. Judgements on what constitutes sensible social distancing measures will be at the heart of everything we do until an effective vaccine is discovered and universally distributed.
Everybody basically has a great excuse to avoid any social obligations they're not keen on for the next few years. Introverts, rejoice.
Regarding different approaches in different parts of the country, Minister of Cooperative Governance and Traditional Affairs, Nkosazana Dlamini-Zuma, did say yesterday that areas worst hit by COVID-19 infections – Gauteng, Western Cape and KwaZulu-Natal – could experience a hard lockdown when this measure is phased out elsewhere
You can read more on that here.
We really are in this for the long haul, folks.
[sources:timeslive&biznews]
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Tis the Forgiveness Season
I need to apologize in advance. I have not read the book that I am about to comment on—I just glanced at the table of contents. I should not, of course, judge a book by its table of contents—hence the apology. My thought process that led me to this book was as follows:
If there are "5 languages of love" could there also be "5 languages of forgiveness"? The notion of (5) different love languages (how we express or want love to be expressed) was popularized by Gary Chapman and is a classic for understanding what is often misaligned (and unspoken) between people in a relationship. Chapman's point is that we want to be loved in the (particular) way we want or are used to. Knowing which love language is the preferred one helps guide us on how to give and receive the love we want.
So I put into the search "languages of apology" and sure enough Gary Chapman has co-authored a book entitled "The 5 Languages of Apology." I expected to find a parallel between the languages of love and apology –but Chapman went off in a different direction for his languages of apology. In this book he outlines a very familiar process of repentance long ago outlined by Jewish tradition. The chapter headings read:
Apology Language #1: Expressing Regret= I am sorry
Apology Language #2: Accepting Responsibility = I was wrong
Apology Language # 3: Making Restitution = What can I do to make it right?
Apology Language #4: Genuinely Repenting = I'll try not to do that again
Apology Language #5: Requesting Forgiveness = Will you please forgive me?
For Chapman, these languages, as in the love languages, are preferences of what people consider a real apology. The Jewish version of these languages suggests that all 5 are necessary for a full and get discount viagra online sincere apology and that these different languages are a sequential process of repentance. Granted one or two may be more important for the person you need to apologize to—the Jewish view addresses what is entailed in a complete process of repenting. To that end Apology Language #4, "I'll try" would be seen as a weak substitute for "I am committed" to not do that again. From our Kabbalah study Apology Language #4 goes even deeper = "I am no longer the person for whom doing that again would be possible."
Yesterday I had the privilege of attending the funeral service of Rob Mintz, dear husband of Lisa, a student of ours. I did not know Rob before I entered Temple Emanuel, but his daughter, friends and the Rabbis painted a lasting impression of a man who often needed to apologize and did so in exquisite fashion.
As in the time when Rob was out to dinner with Lisa and he became increasingly annoyed at a young couple seated at the table next to them. They were both on their phones texting incessantly. Rob at first made a comment under his breath but as their behavior continued he voiced his indignation loud enough so that the couple heard him and their response shifted him on 'his' dime, buying them drinks as an offer of apology for his criticism. The couple informed him that they were texting their family and friends with good news—they had just become engaged to be married.
Whatever language you may choose, it is the season to ask for and to grant forgiveness. Words, while they may be one (or a few) of the languages of apology must be reflected in action and in the following change: "I am no longer the person for whom doing that would be possible."
Peggy Brody
"I am no longer the person…" Oh, that it would be possible to change that quickly, to believe it, to say it and to do it….To me those words sound almost empty as I, for one, probably would be unable to live up to them immediately. I would hope at least I would be aware and could make the change in time. What sayest thou? Peggy
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Where d you go download. Fort Minor
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Where'd You Go (Fort Minor song)
Hence We Are Not Violating Any Terms from this Website. The song reached its peak at number ten on its fourth week. Back at work, he prepares to go home, but is then given another stack of documents. Erica Doyle, Thomas Glave, Jewelle Gomez, D. Free Download Snowman Where D You Go Best Song Mp3 for Free Welcome to BestSong.
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The sunlit island, its mountains and beaches, its tapas and tennis courts, also promise an escape from the tensions simmering at home in Manhattan. For the Posts, a two-week trip to the Balearic island of Mallorca with their extended family and friends is a celebration: Franny and Jim are observing their thirty-fifth wedding anniversary, and their daughter, Sylvia, has graduated from high school. When her daughter Bee claims a family trip to Antarctica as a reward for perfect grades, Bernadette, a fiercely intelligent shut in, throws herself into preparations for the trip But worn down by years of trying to live the Seattle life she never wanted, Ms Fox is on the brink of a meltdown And after a school fundraiser goes disastrously awry Bernadette Fox has vanished. It features interviews with three different families: a little boy, who has divorced parents and has to undertake numerous chores; the wife of a baseball player caring for their children; and the parents of a soldier in Iraq. Originally full of life, the protagonist becomes a robot working a monotonous office job. Note: insert 200636 into search.
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Today she will shower and put on real clothes. When she was ten years old, her 40-year-old father died of a sudden heart attack. In the Czech Republic, the song debuted at No. And just when it seems that things can't go more awry, a former colleague produces a relic from the past - a graphic memoir with pages telling of family secrets long buried and a sister to whom Eleanor never speaks. The song features who at the time went by the stage name Holly Brook and , lead singer of the rock group.
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Snowman Where D You Go Song Download Mp3 Free Free Download Snowman Where D You Go Song Mp3 for Free in hd quality uploaded by Sadie Pincus on BestSong. To design experts, she's a revolutionary architect. They were listed as the nineteenth biggest one-hit wonder of the 2000s. Cate Blanchett was born on May 14, 1969 in Melbourne, Victoria, Australia, to June Gamble , an Australian teacher and property developer, and Robert DeWitt Blanchett, Jr. The entire song is performed in with some subtitles. The single reached number nine on the chart on June 24, 2006, as well as number five in the chart on May 20, 2006. He leaves for work, and his buried alter egos, dressed in white shirts, black slacks, assorted ties and each holding either red or white roses, emerge mysteriously.
Search for your favorite songs in sites and download these mp3 file in the best hd quality for free licensed music. Meanwhile, at home, the alter egos are in a circle around his coffee table, throw the roses in the center, and leave. And Bee must take a trip to the end of the earth to find her. The song spent fourteen weeks on the chart. If you've enjoyed the book, then this will be a must read delight for you! A vocabulary activity and vocabulary test with answers ;7. She will initiate sex with her husband, Joe. Violet Parry is living the quintessential life of luxury in the Hollywood Hills with David, her rock-and-roll manager husband, and her darling toddler, Dot.
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She will attend her yoga class after dropping her son, Timby, off at school. For today is the day Timby has decided to pretend to be ill to weasel his way into his mother's company. It is the fourth and final single from Fort Minor's debut album , released on April 14, 2006. In France, the song debuted and peaked at number twenty-four on October 28, 2006. The two also performed the song on and. She has an older brother and a younger sister. Before Download Snowman Where D You Go Song Mp3 you can preview this song use Play to listen this song music and use Download button to save this file.
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He runs home not knowing what he is running for, and at the moment that he walks in the door, the last of the alter egos exits. In New Zealand, the song debuted on the at No. Shinoda requested Brook to sing the chorus, since Shinoda had already written the entire song. Among the Bravos is nineteen-year-old Specialist Billy Lynn. At its third week, the single reached the No. The scenes where the three vocalists sing also shifts to shots of the families' belongings, homes and neighborhoods.
The winning video was directed by David Ly, a graduate film student at. You may call yourself a fan, but few truly are. Over the course of this day, Billy will drink and brawl, yearn for home and mourn those missing, face a heart-wrenching decision and discover pure love and a bitter wisdom far beyond his years. In the Netherlands, the song debuted at chart at number thirty-three. Whether you're looking for new materials to the book or would like to take the challenge yourself and share it with your friends and family for a time of fun, Trivia-on-Books provides a unique approach to Where'd You Go, Bernadette by Maria Semple that is both insightful and educational! The winner of the contest would win a sketch painting by Shinoda that was included in the album's art. Brook and Matranga's vocal ranges span from the low note of 3 to the high note of B 4. .


SportLocal Sport
sport, local-sport,
Wodonga co-coach Jack Craig says teenage opener Michael Grohmann has the club's best work ethic. Given the Bulldogs have built a reputation as one of the league's most professional outfits and boast former Australian Country batsman and fitness fanatic Robbie Jackson, it points to the 16-year-old's desire to succeed. "There's nobody else at Wodonga Bulldogs that's worked harder than Michael has this year," Craig said. "He's been in the nets I'd say four weeks before we started pre-season, hitting thousands of balls. "The sheer workload he's put in this year is going to reap the rewards." He struck his first half-century against Wodonga Raiders on November 9. "I had some rep stuff over the winter as well and that really helped, I got to do a lot of work with them," the Year 10 student said. "I also did a lot of work with myself as I didn't have the greatest season last year, so I tried to improve on that. "There were some slight technical flaws at times and I wasn't making the right decisions out in the middle during an innings. "I was just getting a bit too heavily on the front foot, so it's about trying to get a bit more balance at the crease." Grohmann describes his form as "patchy" with three single-figures scores, but Craig says the opening position can be brutal. IN OTHER NEWS: "It's not an easy role, he's playing at the top of the order, the ball is moving around and you're facing the best bowlers in the league, but he's doing the job for us," he said. Wodonga is the only unbeaten team over both formats. The Bulldogs and North have four-nil records at T20 level, while they've claimed five straight wins in the 50-over games. However, that unbeaten streak is set to be tested at North's Bunton Park on Saturday. "This will be one of the first really big games, although there's been some good games so far," Grohmann said. Meanwhile, another of the association's most exciting talents will debut on Saturday. Lavington's 14-year-old Oscar Lyons will face Albury at its Billson Park. The Year Eight student made 80 last week in second grade against Tallangatta to earn a promotion. Ironically, his father Jarrod also played his first game as a 14-year-old for Kooringal Colts in Wagga. Lyons isn't the youngest debutant though with East Albury wicketkeeper Miles Hemann-Petersen just 13 years and 10 months against Belvoir in November, 2017. Elsewhere, Tallangatta is home to Belvoir, which is chasing a fourth straight win. The Eagles hold a one-game break over Tallangatta in a logjam for top six spots. And New City hosts East Albury, while Wodonga Raiders travel to St Patrick's.
https://nnimgt-a.akamaihd.net/transform/v1/crop/frm/andrew.moir/c6fc653a-beae-47d4-b2da-57bcf48ac582.jpg/r0_246_4892_3010_w1200_h678_fmax.jpg
November 29 2019 - 12:13PM
Wodonga coach's praise for teenager Michael Grohmann's work ethic
Andrew Moir
CLASS ACT: Wodonga teenager Michael Grohmann will be chasing another strong effort after his maiden 50 three weeks ago. Picture: MARK JESSER
Wodonga co-coach Jack Craig says teenage opener Michael Grohmann has the club's best work ethic.
Given the Bulldogs have built a reputation as one of the league's most professional outfits and boast former Australian Country batsman and fitness fanatic Robbie Jackson, it points to the 16-year-old's desire to succeed.
"There's nobody else at Wodonga Bulldogs that's worked harder than Michael has this year," Craig said.
"He's been in the nets I'd say four weeks before we started pre-season, hitting thousands of balls.
"The sheer workload he's put in this year is going to reap the rewards."
He struck his first half-century against Wodonga Raiders on November 9.
"I had some rep stuff over the winter as well and that really helped, I got to do a lot of work with them," the Year 10 student said.
"I also did a lot of work with myself as I didn't have the greatest season last year, so I tried to improve on that.
"There were some slight technical flaws at times and I wasn't making the right decisions out in the middle during an innings.
"I was just getting a bit too heavily on the front foot, so it's about trying to get a bit more balance at the crease."
Grohmann describes his form as "patchy" with three single-figures scores, but Craig says the opening position can be brutal.
MP says council allowed 'multi-million dollar shortfall' in developer fees
'A bond like no other': Mother, two daughters fight cancer
"It's not an easy role, he's playing at the top of the order, the ball is moving around and you're facing the best bowlers in the league, but he's doing the job for us," he said.
Wodonga is the only unbeaten team over both formats.
The Bulldogs and North have four-nil records at T20 level, while they've claimed five straight wins in the 50-over games.
However, that unbeaten streak is set to be tested at North's Bunton Park on Saturday.
"This will be one of the first really big games, although there's been some good games so far," Grohmann said.
Meanwhile, another of the association's most exciting talents will debut on Saturday.
Lavington's 14-year-old Oscar Lyons will face Albury at its Billson Park.
The Year Eight student made 80 last week in second grade against Tallangatta to earn a promotion.
Ironically, his father Jarrod also played his first game as a 14-year-old for Kooringal Colts in Wagga.
Lyons isn't the youngest debutant though with East Albury wicketkeeper Miles Hemann-Petersen just 13 years and 10 months against Belvoir in November, 2017.
Elsewhere, Tallangatta is home to Belvoir, which is chasing a fourth straight win.
The Eagles hold a one-game break over Tallangatta in a logjam for top six spots.
And New City hosts East Albury, while Wodonga Raiders travel to St Patrick's.
'It is about being able to connect': Upper Murray rebuilds
Abbeyard fire: Firefighters slow spread of blaze for now
Home town now soldier's front line
'It's nowhere near the chalet: Grand Old Lady is still safe
Be wary of dodgy offers after fires, regulator warns
Fallen firefighter Samuel McPaul farewelled in Holbrook


The Globe Players
Bringing high quality theatre into schools for 50 years
From Our Actors
Christmas With Dickens!
Not currently touring
The Play's The Thing
Romeo and Juliet (Primary version)
All The World's A Stage (The Tudors)
The Strange Case of Dr. Jekyll and Mr. Hyde
What You Will (An introduction to Shakespeare)
A Christmas Carol (Text Study)
Online, Live-Streamed Performances
Shows not currently touring
What The Dickens! (Secondary)
Desperate Glory (The War Poets)
Outdoor Family Shows
Book / Contact
In our fantastic new touring production of Dr Jekyll and Mr Hyde for secondary schools, key moments are engagingly dramatized along with commentary, discussion of social background and analysis of character. This classic tale grips the audience, just as a good detective story should
All our actors play multiple roles, keeping the action exciting and dynamic. Using our tested dramatic devices we ensure that the story is clearly delivered and that themes and context are thoroughly explored as the ultimate, entertaining aid to learning and exam preparation.
This production follows Mr Hyde's reign of terror: his brutal treatment of a young girl, his crazed murder of a Member of Parliament, and the strange feeling of horror he generates in all who meet him. It also follows Dr Jekyll's absolute refusal to change the terms of his will, leaving everything to Mr Hyde in the circumstances of his, Jekyll's, "disappearance". All of this is regarded by Mr Utterson as a mystery that needs to be solved.
About the text:
The Strange Case of Dr Jekyll and Mr Hyde was published in January 1886. Planned for Christmas a month earlier, in the tradition of "shilling shockers" – tales of horror and mystery to be read during the Christmas season – its appearance had been delayed.
No mere spooky tale for all the family, this is a disturbing story for adults – altogether a darker tale than Charles Dickens' A Christmas Carol, published just over forty years earlier.
The first ever moving pictures appeared eight years after the book was published. And film producers could hardly wait to provide their own take on the story. "The change is displayed with a dramatic ability almost beyond comprehension." This is from a film review. Since that time, all of the 123 film versions of the story have presented this "change" far too early: in the book the "change" is actually described late, in two letters addressed to Mr Utterson. Presenting it any earlier totally destroys the detective-story nature of the piece. And it really is a kind of detective story.
It is the book, not any film, that we are dealing with. So, it is perhaps helpful to try to approach the story with the mind of its first readers. However much some of our young audience may think they know of this story, we ask them to make an imaginative leap: to think of themselves as being among those first readers in 1886. The one character that seems to represent the detective – and, incidentally, the reader – in search of the truth, is Mr Utterson. Like Utterson, the original reader will have spent much of the novel wondering, what is the mysterious hold this evil Mr Hyde seems to have over the respectable Dr Jekyll?
It soon becomes obvious that all the chief characters are members of the "respectable" ruling class. And, they are all men – Victorian men. Respectability to them lies not so much in their actual behaviour, as in how they are perceived by others. Avoiding a scandal is vitally important to their position in society.
Robert Louis Stevenson, our author, had to rely on hints when dealing with some of the aspects of his subject. This is because, as Utterson speculates on possible motivations, the current sexual taboos of the time come into play. Literary censorship was a matter the author had to keep an eye on.
For prices and further information about having The Globe Players visit your school see our FAQs page.
Contact us to book now


Direct Sound
Eko Guitars
Heart Sound
Hering Harmonicas
Izzo Percussion
Liberty Drums
Mike Balter
Techra Drum Sticks
Timbra Top Percussion
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Vater VCS5BN Color Wrap Nylon 5B Nylon Tip Drum Sticks - Silver Optic
The Vater brand was officially established in November of 1991, but the Vater family history with drumsticks started decades earlier, in the basement of Boston's legendary Jack's Drum Shop. There, Alan and Ron's grandfather Jack Adams, hand turned drumsticks for the drummers like Buddy Rich as early as 1956. In the early to mid 1980's, the Vater brothers began producing private-label drumsticks alongside sticks for Vic Firth and Zildjian. A few years of this led to the brothers deciding to move their business to a new factory in Holbrook MA. Over the past decade, the Vater family and product line has expanded greatly, introducing innovative products such as the Splash Stick and Acoustic, and welcoming renowned drummers like Chad Smith, Stewart Copeland, and Josh Freeze. At Vater, our goal is simple...to produce the very best drumsticks and percussion accessories in the world.
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Gophers get to play on New Year's Day
BY foxsports • December 8, 2014
MINNEAPOLIS (AP) The prestige of taking the field on New Year's Day has faded with the expansion and evolution of the bowl system. The national focus has fallen squarely on the four teams in the inaugural College Football Playoff. The championship game will be held more than a week into January.
This matters not to Minnesota. The Gophers will be playing on New Year's Day for the first time in 53 years, quite the feat for a program that has mostly languished in the bottom half of the Big Ten for the last half-century.
''I think it's huge in terms of exposure. You have 16, 17, 18-year-olds all across the country sitting in their living rooms, watching Minnesota play meaningful football,'' senior defensive tackle Cameron Botticelli said.
The Gophers were picked Sunday to play Missouri in the Buffalo Wild Wings Citrus Bowl in Orlando, Florida. The destination itself was warmly welcomed by the coaches eyeing a critical recruiting area, by the 13 players on the roster who are from the Sunshine State and by long-frustrated fans used to late-December bowl games in Houston, the Phoenix area or Nashville.
The fact that the game will be played on Jan. 1, well, that was as good as the Gophers could have hoped for after losing the Big Ten West Division to rival Wisconsin and missing out on the conference championship game.
''I grew up that way,'' coach Jerry Kill said, reflecting on his Kansas roots. ''Your mom puts a ham in the oven, you get your cheese dip and whatever and you sit there, you get your blanket and start watching football, am I right? That's what you've done for years.''
The last New Year's Day game Minnesota played in was the 1962 Rose Bowl, a 21-3 victory over UCLA. That was the second straight trip to Pasadena, California, for those Gophers, who lost 17-7 to Washington the year before but were still picked as national champions for the 1960 season.
Minnesota has played in 14 bowl games since those back-to-back Rose Bowls. Only one, the 2000 Micronpc.com Bowl in Miami Gardens, was in Florida. Of the last nine times the Gophers have gone to a bowl game, three were in Texas, three were in Arizona and three were in Tennessee.
With Florida tied for Wisconsin as the second-most represented state behind Minnesota on the roster, this will be an extra special trip for several key players.
''Playing here in the Midwest, you don't get many opportunities to play back home in Florida,'' said defensive end Thieren Cockran, who is from Homestead, a suburb of Miami. ''I'm trying to get some tickets for all of my family members, so it's been a little chaos.''
Call that a good problem to have.
''We've talked about taking steps. This is another step forward,'' Kill said.


Association between mitral valve prolapse and open-angle glaucoma
Shuo Ju Chiang, Masao Daimon, Li Hsuan Wang, Ming Jui Hung, Nen Chung Chang, Hsiu Chen Lin
Objective Proteoglycans and glycosoaminoglycans play many roles in connective tissue formation, their accumulation in myxomatous tissues may influence the associated mechanical behaviour of the mitral valve, as well as the extracellular matrix of the eye. Open-angle glaucoma (OAG) and mitral valve prolapse (MVP) may share similar phathophysiology. We hypothesised that MVP increased the risk of developing glaucoma. Methods The research was a retrospective cohort study using a longitudinal health insurance database from the National Health Insurance programme. The database was a randomly sampled population of 1 073 891 followed for 13 years from 1996 to 2008. There were 21 677 subjects with MVP, and 86 708 subjects without MVP were propensity score matched and served as a comparison group. Cox proportional hazards analysis was performed and adjusted for several comorbidities to evaluate the adjusted HR for OAG in the MVP group. Results The incidence rate of OAG in patients in the non-MVP and MVP groups were 10.17 and 16.05 per 10 000 person-years, respectively. The adjusted HR for OAG in the MVP group was 1.88 (95% CI 1.58 to 2.23). A significantly elevated risk of OAG in patients with MVP was also identified in the four stratified age groups. The cumulative incidence of OAG was assessed by Kaplan-Meier analysis. The analysis revealed that the MVP group had a higher incidence of OAG than the comparison group during the follow-up period (p
https://doi.org/10.1136/heartjnl-2014-306198
National Health Programs
Propensity Score
Proteoglycans
Chiang, S. J., Daimon, M., Wang, L. H., Hung, M. J., Chang, N. C., & Lin, H. C. (2015). Association between mitral valve prolapse and open-angle glaucoma. Heart, 101(8), 609-615. https://doi.org/10.1136/heartjnl-2014-306198
Association between mitral valve prolapse and open-angle glaucoma. / Chiang, Shuo Ju; Daimon, Masao; Wang, Li Hsuan; Hung, Ming Jui; Chang, Nen Chung; Lin, Hsiu Chen.
In: Heart, Vol. 101, No. 8, 01.04.2015, p. 609-615.
Chiang, SJ, Daimon, M, Wang, LH, Hung, MJ, Chang, NC & Lin, HC 2015, 'Association between mitral valve prolapse and open-angle glaucoma', Heart, vol. 101, no. 8, pp. 609-615. https://doi.org/10.1136/heartjnl-2014-306198
Chiang SJ, Daimon M, Wang LH, Hung MJ, Chang NC, Lin HC. Association between mitral valve prolapse and open-angle glaucoma. Heart. 2015 Apr 1;101(8):609-615. https://doi.org/10.1136/heartjnl-2014-306198
Chiang, Shuo Ju ; Daimon, Masao ; Wang, Li Hsuan ; Hung, Ming Jui ; Chang, Nen Chung ; Lin, Hsiu Chen. / Association between mitral valve prolapse and open-angle glaucoma. In: Heart. 2015 ; Vol. 101, No. 8. pp. 609-615.
@article{f2f20d0abb3e46b584de31df18af1ef1,
title = "Association between mitral valve prolapse and open-angle glaucoma",
abstract = "Objective Proteoglycans and glycosoaminoglycans play many roles in connective tissue formation, their accumulation in myxomatous tissues may influence the associated mechanical behaviour of the mitral valve, as well as the extracellular matrix of the eye. Open-angle glaucoma (OAG) and mitral valve prolapse (MVP) may share similar phathophysiology. We hypothesised that MVP increased the risk of developing glaucoma. Methods The research was a retrospective cohort study using a longitudinal health insurance database from the National Health Insurance programme. The database was a randomly sampled population of 1 073 891 followed for 13 years from 1996 to 2008. There were 21 677 subjects with MVP, and 86 708 subjects without MVP were propensity score matched and served as a comparison group. Cox proportional hazards analysis was performed and adjusted for several comorbidities to evaluate the adjusted HR for OAG in the MVP group. Results The incidence rate of OAG in patients in the non-MVP and MVP groups were 10.17 and 16.05 per 10 000 person-years, respectively. The adjusted HR for OAG in the MVP group was 1.88 (95{\%} CI 1.58 to 2.23). A significantly elevated risk of OAG in patients with MVP was also identified in the four stratified age groups. The cumulative incidence of OAG was assessed by Kaplan-Meier analysis. The analysis revealed that the MVP group had a higher incidence of OAG than the comparison group during the follow-up period (p",
author = "Chiang, {Shuo Ju} and Masao Daimon and Wang, {Li Hsuan} and Hung, {Ming Jui} and Chang, {Nen Chung} and Lin, {Hsiu Chen}",
doi = "10.1136/heartjnl-2014-306198",
journal = "Heart",
T1 - Association between mitral valve prolapse and open-angle glaucoma
AU - Chiang, Shuo Ju
AU - Daimon, Masao
AU - Wang, Li Hsuan
AU - Hung, Ming Jui
N2 - Objective Proteoglycans and glycosoaminoglycans play many roles in connective tissue formation, their accumulation in myxomatous tissues may influence the associated mechanical behaviour of the mitral valve, as well as the extracellular matrix of the eye. Open-angle glaucoma (OAG) and mitral valve prolapse (MVP) may share similar phathophysiology. We hypothesised that MVP increased the risk of developing glaucoma. Methods The research was a retrospective cohort study using a longitudinal health insurance database from the National Health Insurance programme. The database was a randomly sampled population of 1 073 891 followed for 13 years from 1996 to 2008. There were 21 677 subjects with MVP, and 86 708 subjects without MVP were propensity score matched and served as a comparison group. Cox proportional hazards analysis was performed and adjusted for several comorbidities to evaluate the adjusted HR for OAG in the MVP group. Results The incidence rate of OAG in patients in the non-MVP and MVP groups were 10.17 and 16.05 per 10 000 person-years, respectively. The adjusted HR for OAG in the MVP group was 1.88 (95% CI 1.58 to 2.23). A significantly elevated risk of OAG in patients with MVP was also identified in the four stratified age groups. The cumulative incidence of OAG was assessed by Kaplan-Meier analysis. The analysis revealed that the MVP group had a higher incidence of OAG than the comparison group during the follow-up period (p
AB - Objective Proteoglycans and glycosoaminoglycans play many roles in connective tissue formation, their accumulation in myxomatous tissues may influence the associated mechanical behaviour of the mitral valve, as well as the extracellular matrix of the eye. Open-angle glaucoma (OAG) and mitral valve prolapse (MVP) may share similar phathophysiology. We hypothesised that MVP increased the risk of developing glaucoma. Methods The research was a retrospective cohort study using a longitudinal health insurance database from the National Health Insurance programme. The database was a randomly sampled population of 1 073 891 followed for 13 years from 1996 to 2008. There were 21 677 subjects with MVP, and 86 708 subjects without MVP were propensity score matched and served as a comparison group. Cox proportional hazards analysis was performed and adjusted for several comorbidities to evaluate the adjusted HR for OAG in the MVP group. Results The incidence rate of OAG in patients in the non-MVP and MVP groups were 10.17 and 16.05 per 10 000 person-years, respectively. The adjusted HR for OAG in the MVP group was 1.88 (95% CI 1.58 to 2.23). A significantly elevated risk of OAG in patients with MVP was also identified in the four stratified age groups. The cumulative incidence of OAG was assessed by Kaplan-Meier analysis. The analysis revealed that the MVP group had a higher incidence of OAG than the comparison group during the follow-up period (p
U2 - 10.1136/heartjnl-2014-306198
DO - 10.1136/heartjnl-2014-306198
JO - Heart
JF - Heart
10.1136/heartjnl-2014-306198


This entry is our analysis of a review or synthesis of research findings considered particularly relevant to improving outcomes from drug or alcohol interventions in the UK. The original review was not published by Findings; click Title to order a copy. Free reprints may be available from the authors – click prepared e-mail. The summary conveys the findings and views expressed in the review. Below is a commentary from Drug and Alcohol Findings.
A systematic review and meta-analysis of health care utilization outcomes in alcohol screening and brief intervention trials
https://findings.org.uk/PHP/dl.php?file=Bray_JW_1.txt&s=eb&sf=sfnos
A systematic review and meta-analysis of health care utilization outcomes in alcohol screening and brief intervention trials.
Bray J.W., Cowell A.J., Hinde J.M.
Medical Care: 2011, 49(3), p. 287–294.
Unable to obtain a copy by clicking title? Try asking the author for a reprint by adapting this prepared e-mail or by writing to Dr Bray at bray@rti.org.
Screening for risky drinking and offering brief advice slightly reduces later emergency department visits was the main finding of this review, suggesting these programmes can help ease pressure on overloaded departments. Adding to their attraction, some of the evidence comes from studies in the services set to benefit.
Summary Alcohol screening and brief intervention programmes typically ask a few questions to identify risky drinkers among patients attending for medical care unrelated to their drinking and offer brief advice intended to reduce risks to their health and other adverse consequences. The featured review was the first to systematically assess whether (presumably due to health benefits) following such interventions patients less often need to attend for medical care.
The analysts sought English-language publications reporting relevant trials, excluding those focusing on alcohol-dependent populations [Editor's note: commonly thought an inappropriate target for such brief interventions]. The 29 reports they found were published from 1962 to 2010. Of these, 21 reported studies conducted in primary care, four in emergency departments, and four in another hospital setting. All the reports were from studies in western economically advanced nations, including 17 from the USA and six from the UK. Results were analysed on the assumption that (given differences between the trials) there was no single 'true' effect of the interventions from which trial results deviated just by chance, but that different results might reflect real differences in impact. The analysts selected results from the longest follow-up point in each study, usually a year but in some studies several years.
From trials conducted in primary care, 11 reports assessed the use of outpatient medical services following intervention; results were generally not statistically significant and fairly evenly split between increased and decreased use, suggesting that overall there was no appreciable impact. The picture was similar with respect to impacts on inpatient stays. However, emergency department visits were more consistently reduced – seven of 11 reports; a non-significant decrease was the typical finding, though in two US reports from the same trial the fall was significant. Reports which combined all three categories of medical care found no significant impacts.
Results from interventions tested in emergency departments and other hospital settings were generally inconclusive. However, the three reports which documented emergency department visits found decreases, two of which were statistically significant. In respect of interventions actually in emergency department, one British study found subsequent emergency visits were fewer when risky drinkers had been referred for counselling, but across these studies inpatient care and outpatient care were either unaffected or impacts were mixed. In other hospital settings, one trial found a statistically significant decrease in subsequent inpatient stays. Three other reports documented mixed or no effects on outpatient and emergency care.
After describing the results of the trials the analysts attempted to amalgamate them using meta-analytic techniques, but just 11 of the 19 reports provided usable data from distinct trials. With so few it was decided not to divide the trials according to the type of setting in which they were conducted. Findings from the analyses were in line with the descriptive account of the trials. Compared to control patients, across all 11 trials outpatient visits actually increased among patients allocated to a brief intervention, but this finding narrowly missed statistical significance, and the variation between trials was such that it could not be relied on as an indication of the general impact of brief interventions. Results were similar for inpatient stays. Emergency department visits fell relative to control patients and there was relatively little variation across the trials. However, this result was not statistically significant, and even if it was nevertheless real, the effect was marginal.
Both the descriptive review and the meta-analyses suggest that alcohol screening and brief intervention in primary care and in emergency departments slightly reduce the need for later emergency department visits, but there is little or no effect on later inpatient or outpatient medical care. Because emergency care is generally very expensive, interventions in these settings may reduce overall health care cost. Interventions mounted in non-emergency hospital settings appeared to have no effect on later health care utilisation. However, there were too few studies to generate robust policy implications.
In the context of there having been no impact on inpatient stays, the small increase in outpatient care found in the meta-analysis may reflect a desired effect of brief advice – to prompt further help among drinkers whose problems are not so severe as to require admission to hospital.
commentary This analysis speaks to an important issue in brief intervention policy – whether the health services generally responsible for mounting these programmes can expect a pay-off in improved patient health which in turn relieves the load on their services. With this kind of possibility in mind, Britain's national health intervention advisory body has commended screening and brief intervention to NHS and local authorities as an essential strand in an "invest to save" strategy to prevent problem drinking. The only real hope the featured review holds out is that screening for risky drinking and offering brief advice in GPs' surgeries and in emergency departments may mean slightly fewer emergency visits in the future. Given the pressure on emergency departments in Britain, this may seem a worthwhile potential addition to any other benefits to the patients and their associates from reduced drinking. However, this hope rests mainly on two studies which did not duplicate how brief interventions would usually be implemented. Details below.
The finding in the meta-analysis that brief interventions may cut later recourse to emergency departments appears to rely largely on two US trials. Rather than attempting to approach all relevant patients in the emergency department, the first study recruited inpatients admitted for at least 24 hours to a trauma centre. The 30-minute intervention was delivered not by the hospital's medical staff but by a psychologist trained in brief interventions, and was followed up a month later by a handwritten letter. Given the nature of the injuries sustained by these patients (falls and traffic accidents accounted for about half), it seems likely that many were related to recent heavy drinking, a persuasive hook for the intervention. Nearly half the patients had previously been counselled about their drinking, further indication that this was not a usual emergency department sample. In a second study, the 'brief' intervention was unusually extensive – two advice sessions with a family doctor and two follow-up calls from a nurse – and the control intervention which it outperformed could not be considered acceptable medical care. Control patients were merely handed a general health advice booklet which would not have signalled to them that they had a drinking problem, and their doctors were not told that screening had indicated heavy drinking, depriving them of an opportunity to address the issue during the routine medical consultation.
A third study which found reduced emergency care (in another three trials, results were in the 'wrong' direction) came from the UK. Based on their own accounts, over the following 12 months patients randomly allocated after screening to an appointment with an alcohol adviser had made slightly fewer visits to an emergency unit than those simply handed an alcohol advice leaflet and told by emergency staff that their drinking might be harmful. The difference of on average 0.90 attendances versus 0.97 per patient was statistically insignificant, and the number of times patients had needed an ambulance was virtually the same regardless of intervention. This data (which was included in the featured review) was based on fewer than half the patients in the study. However, the unit's own attendance records revealed that patients allocated to advice had returned nearly 30% fewer times than patients simply handed the leaflet – a difference which was statistically significant. Though not reliant on following patients up, this finding too suffered from loss of patients to the study; of those who had screened positive for risky drinking, only about half entered the trial. Notably these results reflected the impact of adding an offer of further advice (which only a minority took up) to the potentially powerful warning from unit staff, itself a (presumably very) brief intervention. Without this systematically applied warning the advantage gained by the offer of advice might have been greater.
What about injuries?
If the impact on emergency department visits is real, presumably a major mechanism is the reduction of injuries. For the evidence we can turn to a Cochrane review which investigated injury reductions after interventions targeting problem drinking. When the analysis narrowed in on brief interventions, five of the seven relevant trials were found to have recorded fewer injuries after intervention than in a control group, and in two the differences were statistically significant. Interestingly, these two trials did not find reductions in drinking; across all the studies, injury reductions often did not parallel drinking reductions and vice versa.
From emergency departments in particular there is little evidence, and findings are patchy though on balance positive. Among studies which compared brief against no intervention, one review which focused on injured patients found two studies in which injuries were further reduced by intervention, and one in which they were not. Another similar review did not confine itself to injured patients, but excluded studies where the intervention was conducted during follow-on inpatient care. Combined findings showed that six to 12 months later, interventions patients were about half as likely as comparison patients to have suffered an alcohol-related injury. The three studies on which this estimate was based were all from the USA. Two (1 2) involved only teenage patients whose drinking would have been illegal in that country. The third did recruit adults, offering a one-hour motivational interview plus for some patients a further session a week or so later, which nearly 70% attended. Only those offered (and especially those who attended) this 'booster' experienced significantly fewer injuries than control group patients who received no special intervention.
In GP-based primary care the main feature is the lack of studies. The US study referred to above which featured an unusually extensive intervention did find this was followed over the next four years by fewer traffic accidents causing death or injury compared to the record of patients offered no alcohol-focused advice by the study. Apart from this, the evidence bank seems empty. Absence of evidence is also the main feature for studies based in general hospital wards.
Last revised 28 December 2013. First uploaded 19 December 2013
STUDY 2012 Usefulness of brief intervention for patients admitted to emergency services for acute alcohol intoxication
STUDY 2003 Family doctors' alcohol advice plus follow up cuts long-term medical and social costs
STUDY 2011 Randomized controlled trial of a brief intervention for unhealthy alcohol use in hospitalized Taiwanese men
STUDY 2012 Alcohol screening and brief intervention in emergency departments
STUDY 2014 The effectiveness of alcohol screening and brief intervention in emergency departments: a multicentre pragmatic cluster randomized controlled trial
REVIEW 2016 Emergency department-based brief interventions for individuals with substance-related problems: A review of effectiveness
STUDY 2005 Heavily drinking emergency patients cut down after referral for counselling
STUDY 2003 Injury rate cut in heavy drinking accident and emergency patients
STUDY 2006 A&E units save health service resources by addressing drinking
REVIEW 2013 Interventions for reducing alcohol consumption among general hospital inpatient heavy alcohol users: a systematic review


What's in Walla Walla's Wallet?
Economic study reveals wine industry creating significant impact
BY OWP STAFF
Just as Walla Walla Valley wine delivers on the palate, the region's wine industry also yields a major impact to the economy, contributing hundreds of millions of dollars of activity. The "Economic Impact of the Walla Walla Wine Industry," a study released in early May, details the importance of wine to the area's prosperity.
Authored by a team led by Dr. Nick Velluzzi of Walla Walla Community College and commissioned by the City of Walla Walla, Port of Walla Walla, Visit Walla Walla and the Walla Walla Valley Wine Alliance, the study proves the wine trade's staggering impact.
According to the research, the Walla Walla wine industry, directly or indirectly, supported 2,484 wine and tourism jobs in 2018 — nearly 10% of all employed Walla Walla County residents — and accounted for labor income of $114 million, an average of $45,894 in annual income per worker. In all, the report estimates the industry generated some $430 million in business sales and injected $17.4 million in tax revenues into local government coffers.
The study specifically targeted consumers who cited visits to wineries and/or tasting rooms as the primary reason for their trip. Those who visited the Valley for purposes other than wine were eliminated from the sample set. The findings suggest these visitors spent $145 million in 2018 in combined lodging, food and wine expenditures.
"Our research shows that the value contribution of the combined effects of wine production and wine-related tourism in the Walla Walla Valley is immense," says Velluzzi, the executive director of institutional effectiveness for the college. "According to these results, the wine industry is clearly one of the most important economic drivers in the region."
The study — co-authored by Bill Beyers of the University of Washington and Don Morgan of GMA Research Corp. in Bellevue, Washington — is believed to be the first of its kind. Researchers examined surveys of visitors to Walla Walla as well as the region's wineries and tasting rooms over the course of 2018 to get a comprehensive view of the combined economic impact of wine production, wine tasting room activity and tourist activity stimulated by the wine industry in Walla Walla and Umatilla counties. Vineyards were not surveyed as part of the study, which means sales of grapes to other wineries were not included.
"The wine industry is indispensable to the Walla Walla tourism industry," says Ron Williams, CEO of Visit Walla Walla. "Not only does the wine industry directly attract thousands of visitors each year, it indirectly helps support Walla Walla's innovative culinary scene, and its robust arts and entertainment culture. That helps improve the quality of life for all of us in the Walla Walla Valley, which is also important in making Walla Walla such a unique destination."
When asked to identify the attributes most closely associated with Walla Walla, among the most frequent responses were: the high quality of the wine; friendly, family-run wineries; and the charming town — and the No. 1 response.
"Our members take great pride in being a valuable contributor to Walla Walla and its surrounding areas," says Ashley Mahan, chief operating officer of the Walla Walla Valley Wine Alliance. "Through their hard work and passion, Walla Walla's reputation as a world-class wine region has become internationally known. And that has helped the economy thrive for all of us in Walla Walla."
To learn more about the Walla Walla Valley Wine Alliance and its members, visit wallawallawine.com. For more information on planning a trip or to directly book a visit to Walla Walla, go to www.visitwallawalla.com
Some Stats
$123 million: Combined revenue of wineries and independent tasting rooms in 2018.
$25.62 million: Labor income for winery and independent tasting room workers in 2018.
56%: Percentage of winery revenue from direct sales via tasting rooms, clubs and e-commerce in 2018.
$60 million: Money spent by wine tourists on wine purchases in 2018.
$145 million: The total money spent by wine tourists in 2018.
$812: Average money wine visitors spent per trip in 2018.
60%: Percentage of survey respondents who've been visiting the region since at least 2014.


Tan France Drinks 6-7 Cups of This 'Gorgeous Coffee'
by Produced by Digital Editors twitter | More Articles: Celebrity
Celebrity Tan France | Getty Images
Tanveer Wasim, better known as Tan France, is the lovable stylist on the Netflix original series Queer Eye. Fans can't get enough of his good looks, charming personality, and unbeatable lifestyle advice.
The fashion expert recently became part of the "Stir It Up" marketing campaign for Starbucks, referring to his favorite brew as "gorgeous coffee." France admits drinking six or seven cups of it a day.
Who is Tan France?
Part of the illustrious "Fab Five" on Queer Eye, France moved from England to the United States in 2008 to pursue a fashion career.
Raised by strict Muslim Pakistani parents, the 38-year-old has founded several women's clothing lines. In 2018, his infamous role on Queer Eye launched his career as a television personality.
According to IMDb, France has appeared in several successful television series, such as Dressing Funny, Next in Fashion, and Heads Will Roll. The personable stylist has been a guest host on NBC's Today and even made an appearance in Taylor Swift's music video, "You Need to Calm Down."
Discussing his partnership with Starbucks, France told The Strategist:
To make myself sound better, I should probably say I only drink coffee a couple times a day. But the truth is I drink about six or seven cups, minimum. To be fair, I have increased my intake over the last few years because my schedule is kind of packed, and coffee gives me the boost I need. I don't drink soda or anything like that, coffee is my thing. I'm a big fan of Starbucks medium-roast coffee, and the Premium Instant variety is so much more convenient, especially when I'm home. It tastes exactly like the medium roast you get at a Starbucks store. It's honestly gorgeous coffee.
How to get your own cup of 'gorgeous coffee'
Introducing @Starbucks premium instant coffee, a range of delicious medium and dark roast coffees and coffee beverages inspired by Starbucks coffee houses and drawing on our expertise in instant coffee. Learn more: https://t.co/pMCZKnPN6a #Innovation pic.twitter.com/l1drFZ5goR
— Nestlé (@Nestle) February 25, 2020
France has partnered with Starbucks to promote their line of instant coffee. The Seattle-based coffee company says the high-quality beans are "ethically sourced" and the same ones used in Starbucks cafes throughout the world.
Made with 100 percent arabica coffee, the Premium Instant coffee line is available in medium roast, which is France's favorite blend. Starbucks describes it as a "perfectly balanced Latin American coffee with creamy notes of milk chocolate and nuts." A dark roast with "sweet, toasted flavor" is also available, along with a blonde roast that is "bright and complex."
A 3.17-ounce canister makes up to 40 cups and has a suggested retail price of $9.99. It is available online at Amazon for $13 and can also be found in most major grocery store chains.
The Starbucks 'Stir It Up' Campaign
#sponsored After a year of 'been there, (over)done that' routines, I'm thrilled to partner with @Starbucks to add some serious taste to your morning — with all-new Starbucks Premium Instant coffee (and a few tips from yours truly?). https://t.co/3jNpHMgqEW #StarbucksAtHome pic.twitter.com/4s1XzvO5B4
— Tan France (@tanfrance) June 21, 2021
'Queer Eye' Fashion Expert Tan France Premieres His Book 'Naturally Tan'
Starbucks recently announced, "As part of the campaign, Tan is sharing his tips and tricks to add a little 'wow' to your daily routine – starting with infusing some exceptional taste into your morning with all-new Starbucks® Premium Instant coffee."
Some of his top tips include changing your morning alarm ringtone, wearing some comfy loungewear around the house, and making space on your kitchen counter for a work-from-home coffee station.
A huge fan of the instant coffee line, France says, "the only thing you need to enjoy it is the smallest coffee maker in the world: a spoon."
The fashionista, who is expecting his first child this summer, told Distractify, "the new Starbucks® Premium Instant coffee has changed his routine because it only takes a minute to prepare." France explained, "It gets me back many minutes, so now I have a few minutes to dance around to Bollywood music when I'm getting ready, which is always nice."
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