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Add HGNC-mapped STRING and CRISPR GeneEffect representations
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{
"embedding": "string_prot",
"species": "Homo sapiens",
"shape": [
19699,
1024
],
"dtype": "float32",
"gene_identifier": "Current HGNC symbol for one-to-one mappings; original identifier for unresolved or duplicate-symbol groups",
"row_order": "genes.json[i] identifies embeddings.npy[i]; row_mapping.csv is in the same order",
"origin": {
"database": "STRING",
"version": "12.5",
"taxon_id": 9606,
"representation": "ProtT5 protein sequence embeddings",
"url": "https://stringdb-downloads.org/download/protein.sequence.embeddings.v12.5/9606.protein.sequence.embeddings.v12.5.h5",
"filename": "9606.protein.sequence.embeddings.v12.5.h5",
"sha256": "717315896d6a2ee349961c34a08ee57c44ca273179035640752cabc2c75b51ff",
"auxiliary_files": [
{
"filename": "9606.protein.info.v12.5.txt.gz",
"sha256": "144de4b0d98c6a7dfde6ddc2591cf88657f27b989eadff4f501450c3ed1f0f1c",
"url": "https://stringdb-downloads.org/download/protein.info.v12.5/9606.protein.info.v12.5.txt.gz"
},
{
"filename": "9606.protein.aliases.v12.5.txt.gz",
"sha256": "b65f730b993ed0c1bd72edf4565d3d425db42861101b29699704810e8f125680",
"url": "https://stringdb-downloads.org/download/protein.aliases.v12.5/9606.protein.aliases.v12.5.txt.gz"
}
],
"citations": [
"https://doi.org/10.1093/bioinformatics/btaf496",
"https://doi.org/10.1093/nar/gkae1113"
],
"license": "CC BY 4.0",
"license_evidence": "https://string-db.org/cgi/download?species_text=Homo+sapiens"
},
"preprocessing": {
"filtering": "None; all source proteins retained",
"normalization": "None",
"pooling": "None",
"conversion": "float16 -> float32, exactly preserving the stored source values",
"row_order": "Original HDF5 protein order; differs between network and sequence files"
},
"identifier_mapping": {
"authority": "HGNC approved complete set",
"url": "https://storage.googleapis.com/public-download-files/hgnc/tsv/tsv/hgnc_complete_set.txt",
"sha256": "2828618d23d315be76ea415f7ef0e951858716ebab07e2d584190f52e5178c1e",
"snapshot_retrieved_utc": "2026-10-14T20:45:19.024543+00:00",
"latest_record_date_modified": "2026-10-12",
"approved_records": 45277,
"license": "CC0",
"license_url": "https://www.genenames.org/about/license/",
"collision_policy": "Keep all rows. Use current symbols for one-to-one mappings; retain original names for all members of duplicate-symbol groups and for unresolved/ambiguous mappings.",
"case_policy": "Exact, case-sensitive identifier matching; no suffix stripping or guessed renaming",
"row_mapping": "row_mapping.csv is in embeddings.npy row order and records canonical symbols, stable IDs, evidence and publication identifiers",
"method": "Intersect nonempty HGNC-ID, Ensembl-gene-ID and Entrez-ID candidate sets from STRING aliases; unresolved conflicts stay unresolved. When no stable-ID candidates exist, try UniProt, preferred current symbol, annotated current symbol, preferred previous symbol, then preferred alias; require one candidate.",
"statistics": {
"rows": 19699,
"resolved_to_hgnc": 19415,
"unmapped": 279,
"ambiguous": 5,
"duplicate_canonical_symbols": 40,
"rows_in_duplicate_symbol_groups": 80,
"renamed_identifiers": 540,
"exported_identifiers_that_are_current_hgnc_symbols": 19373,
"identifier_policies": {
"canonical_symbol": 19334,
"original_duplicate_symbol": 80,
"original_unresolved": 283,
"original_identifier_collision": 2
}
}
},
"files": {
"embeddings.npy": {
"sha256": "49c1819e87481d148664fd937c1bc4de5e4f76927482f8404dbe2d00082c8c89",
"bytes": 80687232
},
"genes.json": {
"sha256": "b5744126c6fb5860c23d0bb95f2ef3f4ed7119224f465fb98c62a724a8d2236e",
"bytes": 227603
},
"proteins.json": {
"sha256": "9c45acce94c8412afda73743f770ce27f82524fcbcec7a21ff9e14fb8ac6cf0a",
"bytes": 512177
},
"row_mapping.csv": {
"sha256": "6d692b7ad32311c95cc97c025d5de87667e8de9e4d0aded121b863b72b7f37d4",
"bytes": 5089646
}
},
"verification": "Every reloaded vector exactly equals its source cast to float32; every input row retained; unique published IDs and row mapping checked; no added WT row."
}