diff --git "a/ethno_sample_400.json" "b/ethno_sample_400.json"
--- "a/ethno_sample_400.json"
+++ "b/ethno_sample_400.json"
@@ -1,183 +1,33 @@
 [
-  {
-    "chemical": "PROTEIN",
-    "plant_species": "Abelmoschus esculentus",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 3280238,
-    "clinical_trials_count_2026": 42,
-    "chembl_bioactivity_count": 292,
-    "patent_count_since_2020": 12
-  },
-  {
-    "chemical": "PROTEINS",
-    "plant_species": "Juglans nigra",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 1528854,
-    "clinical_trials_count_2026": 13,
-    "chembl_bioactivity_count": 463,
-    "patent_count_since_2020": 3
-  },
-  {
-    "chemical": "WATER",
-    "plant_species": "Abelmoschus esculentus",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 1136912,
-    "clinical_trials_count_2026": 23,
-    "chembl_bioactivity_count": 473,
-    "patent_count_since_2020": 23
-  },
-  {
-    "chemical": "LEAD",
-    "plant_species": "Allium cepa",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 917532,
-    "clinical_trials_count_2026": 21,
-    "chembl_bioactivity_count": 471,
-    "patent_count_since_2020": 21
-  },
-  {
-    "chemical": "GLUCOSE",
-    "plant_species": "Abies spectabilis",
-    "application": "Acetylcholinergic",
-    "dosage": null,
-    "pubmed_mentions_2026": 637114,
-    "clinical_trials_count_2026": 22,
-    "chembl_bioactivity_count": 222,
-    "patent_count_since_2020": 2
-  },
-  {
-    "chemical": "CALCIUM",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "AntiPMS",
-    "dosage": "1 g/day",
-    "pubmed_mentions_2026": 473058,
-    "clinical_trials_count_2026": 30,
-    "chembl_bioactivity_count": 330,
-    "patent_count_since_2020": 10
-  },
-  {
-    "chemical": "SODIUM",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Hypertensive",
-    "dosage": null,
-    "pubmed_mentions_2026": 451297,
-    "clinical_trials_count_2026": 38,
-    "chembl_bioactivity_count": 138,
-    "patent_count_since_2020": 8
-  },
-  {
-    "chemical": "ALCOHOL",
-    "plant_species": "Glycyrrhiza glabra",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 349640,
-    "clinical_trials_count_2026": 4,
-    "chembl_bioactivity_count": 54,
-    "patent_count_since_2020": 14
-  },
-  {
-    "chemical": "INCLUDES",
-    "plant_species": "Plumeria acutifolia",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 340414,
-    "clinical_trials_count_2026": 46,
-    "chembl_bioactivity_count": 496,
-    "patent_count_since_2020": 26
-  },
   {
     "chemical": "CHOLESTEROL",
-    "plant_species": "Abelmoschus moschatus",
+    "plant_species": "Allium cepa",
     "application": "Antioxidant",
     "dosage": "IC43=10 uM",
     "pubmed_mentions_2026": 313849,
-    "clinical_trials_count_2026": 43,
-    "chembl_bioactivity_count": 93,
-    "patent_count_since_2020": 3
-  },
-  {
-    "chemical": "PHOSPHATE",
-    "plant_species": "Aspalathus linearis",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 311625,
-    "clinical_trials_count_2026": 42,
-    "chembl_bioactivity_count": 492,
-    "patent_count_since_2020": 22
-  },
-  {
-    "chemical": "NITROGEN",
-    "plant_species": "Abies spectabilis",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 290642,
-    "clinical_trials_count_2026": 3,
-    "chembl_bioactivity_count": 253,
-    "patent_count_since_2020": 3
-  },
-  {
-    "chemical": "IRON",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Antiakathisic",
-    "dosage": null,
-    "pubmed_mentions_2026": 267600,
-    "clinical_trials_count_2026": 41,
-    "chembl_bioactivity_count": 391,
-    "patent_count_since_2020": 21
+    "clinical_trials_count_2026": 70,
+    "chembl_bioactivity_count": 135,
+    "patent_count_since_2020": 383
   },
   {
     "chemical": "AMINO-ACIDS",
-    "plant_species": "Acacia farnesiana",
+    "plant_species": "Panax quinquefolius",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 265380,
-    "clinical_trials_count_2026": 29,
-    "chembl_bioactivity_count": 179,
-    "patent_count_since_2020": 9
-  },
-  {
-    "chemical": "INFUSION",
-    "plant_species": "Elytrigia repens",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 257101,
-    "clinical_trials_count_2026": 3,
-    "chembl_bioactivity_count": 103,
-    "patent_count_since_2020": 3
-  },
-  {
-    "chemical": "GOLD",
-    "plant_species": "Anacardium occidentale",
-    "application": "Antiarthritic",
-    "dosage": null,
-    "pubmed_mentions_2026": 239277,
-    "clinical_trials_count_2026": 22,
-    "chembl_bioactivity_count": 272,
-    "patent_count_since_2020": 22
-  },
-  {
-    "chemical": "FIBER",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Antidiabetic",
-    "dosage": null,
-    "pubmed_mentions_2026": 225370,
-    "clinical_trials_count_2026": 42,
-    "chembl_bioactivity_count": 342,
-    "patent_count_since_2020": 2
+    "clinical_trials_count_2026": 1,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 4
   },
   {
     "chemical": "TYROSINE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Zingiber officinale",
     "application": "Antidepressant?",
     "dosage": null,
     "pubmed_mentions_2026": 222127,
-    "clinical_trials_count_2026": 20,
-    "chembl_bioactivity_count": 270,
-    "patent_count_since_2020": 10
+    "clinical_trials_count_2026": 86,
+    "chembl_bioactivity_count": 198,
+    "patent_count_since_2020": 578
   },
   {
     "chemical": "ALBUMIN",
@@ -185,79 +35,39 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 199616,
-    "clinical_trials_count_2026": 33,
-    "chembl_bioactivity_count": 133,
-    "patent_count_since_2020": 23
+    "clinical_trials_count_2026": 710,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 342
   },
   {
     "chemical": "FATTY-ACIDS",
-    "plant_species": "Carica papaya",
+    "plant_species": "Duboisia myoporoides",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 196805,
-    "clinical_trials_count_2026": 35,
-    "chembl_bioactivity_count": 335,
-    "patent_count_since_2020": 15
-  },
-  {
-    "chemical": "CHLORIDE",
-    "plant_species": "Aloe vera",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 181420,
-    "clinical_trials_count_2026": 9,
-    "chembl_bioactivity_count": 209,
-    "patent_count_since_2020": 19
+    "clinical_trials_count_2026": 0,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 0
   },
   {
     "chemical": "PHOSPHATASE",
-    "plant_species": "Acacia catechu",
+    "plant_species": "Castanea sativa",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 180957,
-    "clinical_trials_count_2026": 46,
-    "chembl_bioactivity_count": 296,
-    "patent_count_since_2020": 6
-  },
-  {
-    "chemical": "SULFATE",
-    "plant_species": "Aspalathus linearis",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 176627,
-    "clinical_trials_count_2026": 1,
-    "chembl_bioactivity_count": 51,
-    "patent_count_since_2020": 1
-  },
-  {
-    "chemical": "POTASSIUM",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Antiarrhythmic",
-    "dosage": null,
-    "pubmed_mentions_2026": 175989,
-    "clinical_trials_count_2026": 22,
-    "chembl_bioactivity_count": 72,
-    "patent_count_since_2020": 2
+    "clinical_trials_count_2026": 14,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 195
   },
   {
     "chemical": "GLUTATHIONE",
-    "plant_species": "Allium cepa",
+    "plant_species": "Arachis hypogaea",
     "application": "Anticytotoxic",
     "dosage": null,
     "pubmed_mentions_2026": 173533,
-    "clinical_trials_count_2026": 6,
-    "chembl_bioactivity_count": 56,
-    "patent_count_since_2020": 16
-  },
-  {
-    "chemical": "ZINC",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "AntiCrohn's",
-    "dosage": null,
-    "pubmed_mentions_2026": 167996,
-    "clinical_trials_count_2026": 18,
-    "chembl_bioactivity_count": 18,
-    "patent_count_since_2020": 18
+    "clinical_trials_count_2026": 52,
+    "chembl_bioactivity_count": 158,
+    "patent_count_since_2020": 130
   },
   {
     "chemical": "CREATININE",
@@ -265,39 +75,19 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 154206,
-    "clinical_trials_count_2026": 9,
-    "chembl_bioactivity_count": 209,
-    "patent_count_since_2020": 19
-  },
-  {
-    "chemical": "ETHANOL",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Allergenic",
-    "dosage": null,
-    "pubmed_mentions_2026": 152547,
-    "clinical_trials_count_2026": 32,
-    "chembl_bioactivity_count": 132,
-    "patent_count_since_2020": 22
+    "clinical_trials_count_2026": 68,
+    "chembl_bioactivity_count": 58,
+    "patent_count_since_2020": 63
   },
   {
     "chemical": "DOPAMINE",
-    "plant_species": "Annona reticulata",
+    "plant_species": "Musa x paradisiaca",
     "application": "Adrenergic",
     "dosage": null,
     "pubmed_mentions_2026": 151646,
-    "clinical_trials_count_2026": 26,
-    "chembl_bioactivity_count": 326,
-    "patent_count_since_2020": 26
-  },
-  {
-    "chemical": "COPPER",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Antiarthritic",
-    "dosage": null,
-    "pubmed_mentions_2026": 150619,
-    "clinical_trials_count_2026": 39,
-    "chembl_bioactivity_count": 439,
-    "patent_count_since_2020": 9
+    "clinical_trials_count_2026": 70,
+    "chembl_bioactivity_count": 957,
+    "patent_count_since_2020": 218
   },
   {
     "chemical": "ESTROGEN",
@@ -305,79 +95,69 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 147976,
-    "clinical_trials_count_2026": 1,
-    "chembl_bioactivity_count": 101,
-    "patent_count_since_2020": 11
+    "clinical_trials_count_2026": 142,
+    "chembl_bioactivity_count": 22,
+    "patent_count_since_2020": 201
   },
   {
     "chemical": "CARBOHYDRATE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Ocimum basilicum",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 142231,
-    "clinical_trials_count_2026": 40,
-    "chembl_bioactivity_count": 40,
-    "patent_count_since_2020": 0
+    "clinical_trials_count_2026": 551,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 596
   },
   {
     "chemical": "PROTEASE",
-    "plant_species": "Armoracia rusticana",
+    "plant_species": "Zingiber officinale",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 140377,
-    "clinical_trials_count_2026": 10,
-    "chembl_bioactivity_count": 10,
-    "patent_count_since_2020": 20
+    "clinical_trials_count_2026": 30,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 742
   },
   {
     "chemical": "OXIDASE",
-    "plant_species": "Acacia nilotica",
+    "plant_species": "Cynara cardunculus subsp. cardunculus",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 138809,
-    "clinical_trials_count_2026": 27,
-    "chembl_bioactivity_count": 327,
-    "patent_count_since_2020": 17
+    "clinical_trials_count_2026": 18,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 250
   },
   {
     "chemical": "ADENOSINE",
-    "plant_species": "Aesculus hippocastanum",
+    "plant_species": "Crataegus rhipidophylla",
     "application": "Antiaggregant",
     "dosage": null,
     "pubmed_mentions_2026": 134798,
-    "clinical_trials_count_2026": 26,
-    "chembl_bioactivity_count": 476,
-    "patent_count_since_2020": 26
-  },
-  {
-    "chemical": "SUGAR",
-    "plant_species": "Abelmoschus esculentus",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 132303,
-    "clinical_trials_count_2026": 22,
-    "chembl_bioactivity_count": 72,
-    "patent_count_since_2020": 22
+    "clinical_trials_count_2026": 120,
+    "chembl_bioactivity_count": 725,
+    "patent_count_since_2020": 273
   },
   {
     "chemical": "PEROXIDASE",
-    "plant_species": "Acacia catechu",
+    "plant_species": "Anogeissus latifolia",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 124254,
-    "clinical_trials_count_2026": 45,
-    "chembl_bioactivity_count": 395,
-    "patent_count_since_2020": 25
+    "clinical_trials_count_2026": 1,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 68
   },
   {
     "chemical": "SERINE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Panax ginseng",
     "application": "Cancer-Preventive",
     "dosage": null,
     "pubmed_mentions_2026": 123763,
-    "clinical_trials_count_2026": 30,
-    "chembl_bioactivity_count": 180,
-    "patent_count_since_2020": 20
+    "clinical_trials_count_2026": 53,
+    "chembl_bioactivity_count": 79,
+    "patent_count_since_2020": 336
   },
   {
     "chemical": "AMYLOID",
@@ -385,19 +165,19 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 120722,
-    "clinical_trials_count_2026": 9,
-    "chembl_bioactivity_count": 159,
-    "patent_count_since_2020": 19
+    "clinical_trials_count_2026": 42,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 335
   },
   {
     "chemical": "CYSTEINE",
-    "plant_species": "Acacia senegal",
+    "plant_species": "Zingiber officinale",
     "application": "AntiAddisonian",
     "dosage": null,
     "pubmed_mentions_2026": 116291,
-    "clinical_trials_count_2026": 24,
-    "chembl_bioactivity_count": 174,
-    "patent_count_since_2020": 4
+    "clinical_trials_count_2026": 183,
+    "chembl_bioactivity_count": 17,
+    "patent_count_since_2020": 423
   },
   {
     "chemical": "HISTONE",
@@ -405,19 +185,19 @@
     "application": "Antitumor",
     "dosage": null,
     "pubmed_mentions_2026": 116185,
-    "clinical_trials_count_2026": 3,
-    "chembl_bioactivity_count": 303,
-    "patent_count_since_2020": 3
+    "clinical_trials_count_2026": 8,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 268
   },
   {
     "chemical": "ARGININE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Prunus armeniaca",
     "application": "Antidiabetic?",
     "dosage": null,
     "pubmed_mentions_2026": 115707,
-    "clinical_trials_count_2026": 6,
-    "chembl_bioactivity_count": 406,
-    "patent_count_since_2020": 6
+    "clinical_trials_count_2026": 283,
+    "chembl_bioactivity_count": 167,
+    "patent_count_since_2020": 433
   },
   {
     "chemical": "STEROIDS",
@@ -425,9 +205,9 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 115624,
-    "clinical_trials_count_2026": 7,
-    "chembl_bioactivity_count": 357,
-    "patent_count_since_2020": 17
+    "clinical_trials_count_2026": 110,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 55
   },
   {
     "chemical": "REDUCTASE",
@@ -435,39 +215,29 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 114171,
-    "clinical_trials_count_2026": 40,
-    "chembl_bioactivity_count": 90,
-    "patent_count_since_2020": 10
-  },
-  {
-    "chemical": "UREA",
-    "plant_species": "Aesculus hippocastanum",
-    "application": null,
-    "dosage": null,
-    "pubmed_mentions_2026": 111788,
-    "clinical_trials_count_2026": 1,
-    "chembl_bioactivity_count": 1,
-    "patent_count_since_2020": 11
+    "clinical_trials_count_2026": 16,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 204
   },
   {
     "chemical": "ALANINE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Panax ginseng",
     "application": "Antioxidant",
     "dosage": null,
     "pubmed_mentions_2026": 110184,
-    "clinical_trials_count_2026": 49,
-    "chembl_bioactivity_count": 499,
-    "patent_count_since_2020": 29
+    "clinical_trials_count_2026": 68,
+    "chembl_bioactivity_count": 48,
+    "patent_count_since_2020": 200
   },
   {
     "chemical": "SEROTONIN",
-    "plant_species": "Ananas comosus",
+    "plant_species": "Theobroma cacao",
     "application": "Abortifacient",
     "dosage": null,
     "pubmed_mentions_2026": 109686,
-    "clinical_trials_count_2026": 10,
-    "chembl_bioactivity_count": 110,
-    "patent_count_since_2020": 20
+    "clinical_trials_count_2026": 54,
+    "chembl_bioactivity_count": 985,
+    "patent_count_since_2020": 165
   },
   {
     "chemical": "SUPEROXIDE-DISMUTASE",
@@ -475,19 +245,19 @@
     "application": "Anticystitic",
     "dosage": null,
     "pubmed_mentions_2026": 101600,
-    "clinical_trials_count_2026": 3,
-    "chembl_bioactivity_count": 303,
-    "patent_count_since_2020": 23
+    "clinical_trials_count_2026": 0,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 0
   },
   {
     "chemical": "TESTOSTERONE",
-    "plant_species": "Pinus sylvestris",
+    "plant_species": "Punica granatum",
     "application": "Anabolic",
     "dosage": null,
     "pubmed_mentions_2026": 101052,
-    "clinical_trials_count_2026": 17,
-    "chembl_bioactivity_count": 117,
-    "patent_count_since_2020": 7
+    "clinical_trials_count_2026": 427,
+    "chembl_bioactivity_count": 1648,
+    "patent_count_since_2020": 126
   },
   {
     "chemical": "PROGESTERONE",
@@ -495,9 +265,9 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 100306,
-    "clinical_trials_count_2026": 42,
-    "chembl_bioactivity_count": 142,
-    "patent_count_since_2020": 12
+    "clinical_trials_count_2026": 416,
+    "chembl_bioactivity_count": 1605,
+    "patent_count_since_2020": 76
   },
   {
     "chemical": "(+)-L-LACTIC-ACID",
@@ -505,39 +275,19 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 98714,
-    "clinical_trials_count_2026": 27,
-    "chembl_bioactivity_count": 327,
-    "patent_count_since_2020": 27
-  },
-  {
-    "chemical": "PHOSPHORUS",
-    "plant_species": "Abelmoschus esculentus",
-    "application": "Antiosteoporotic",
-    "dosage": null,
-    "pubmed_mentions_2026": 96194,
-    "clinical_trials_count_2026": 10,
-    "chembl_bioactivity_count": 360,
-    "patent_count_since_2020": 10
+    "clinical_trials_count_2026": 0,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 0
   },
   {
     "chemical": "ESTRADIOL",
-    "plant_species": "Humulus lupulus",
+    "plant_species": "Panax quinquefolius",
     "application": "Carcinogenic",
     "dosage": "(Breast)",
     "pubmed_mentions_2026": 95847,
-    "clinical_trials_count_2026": 15,
-    "chembl_bioactivity_count": 15,
-    "patent_count_since_2020": 15
-  },
-  {
-    "chemical": "SILVER",
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   {
     "chemical": "HEPARIN",
@@ -545,19 +295,19 @@
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     "pubmed_mentions_2026": 90903,
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   },
   {
     "chemical": "LYSINE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Thymus vulgaris",
     "application": "Antialkalotic",
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   {
     "chemical": "VITAMIN-D",
@@ -565,9 +315,9 @@
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     "pubmed_mentions_2026": 89265,
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   {
     "chemical": "PROSTAGLANDIN",
@@ -575,39 +325,19 @@
     "application": "Antiulcer",
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   },
   {
     "chemical": "ADENINE",
-    "plant_species": "Achillea millefolium",
+    "plant_species": "Crataegus monogyna",
     "application": "Antianemic",
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   {
     "chemical": "ALKALINE-PHOSPHATASE",
@@ -615,9 +345,9 @@
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@@ -625,29 +355,19 @@
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   },
   {
     "chemical": "CATALASE",
-    "plant_species": "Allium ampeloprasum",
+    "plant_species": "Theobroma cacao",
     "application": "Antioxidant",
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   {
     "chemical": "TRIGLYCERIDE",
@@ -655,249 +375,139 @@
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   {
     "chemical": "GLYCINE",
-    "plant_species": "Abelmoschus esculentus",
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   {
     "chemical": "ALKALOIDS",
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   {
     "chemical": "IODINE",
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   {
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   {
     "chemical": "LEUCINE",
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   {
     "chemical": "GABA",
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   {
     "chemical": "POLYSACCHARIDE",
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   {
     "chemical": "HISTAMINE",
-    "plant_species": "Brassica oleracea var. capitata l. var. capitata",
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   {
     "chemical": "NOREPINEPHRINE",
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   {
     "chemical": "TRYPTOPHAN",
-    "plant_species": "Abelmoschus esculentus",
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     "application": "Analgesic",
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   {
     "chemical": "ALCOHOLS",
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   {
     "chemical": "PARAFFIN",
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   {
     "chemical": "PHOSPHOLIPIDS",
-    "plant_species": "Abelmoschus manihot",
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   {
     "chemical": "MORPHINE",
@@ -905,89 +515,29 @@
     "application": "Analgesic",
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   {
     "chemical": "METHIONINE",
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+    "plant_species": "Lupinus albus",
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   {
     "chemical": "TRYPSIN",
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   {
     "chemical": "HYDROCARBONS",
@@ -995,39 +545,39 @@
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   {
     "chemical": "LACTATE-DEHYDROGENASE",
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   {
     "chemical": "FLUORIDE",
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   {
     "chemical": "FLAVONOIDS",
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     "chemical": "CYTOCHROME-C",
@@ -1035,9 +585,9 @@
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@@ -1045,19 +595,19 @@
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   {
     "chemical": "PROLINE",
-    "plant_species": "Abelmoschus esculentus",
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   {
     "chemical": "THYMIDINE",
@@ -1065,19 +615,19 @@
     "application": "Antidote? (Methtrexate)",
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   {
     "chemical": "NICOTINE",
-    "plant_species": "Apium graveolens",
+    "plant_species": "Juglans regia",
     "application": "ANS-Paralytic",
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   {
     "chemical": "AMIDE",
@@ -1085,9 +635,9 @@
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   {
     "chemical": "CREATINE",
@@ -1095,9 +645,9 @@
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   {
     "chemical": "CYCLOOXYGENASE",
@@ -1105,39 +655,19 @@
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   {
-    "chemical": "COBALT",
-    "plant_species": "Acacia catechu",
-    "application": "Cardiomyopathogenic",
+    "chemical": "THREONINE",
+    "plant_species": "Brassica nigra",
+    "application": "Antioxidant?",
     "dosage": null,
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     "chemical": "ALDEHYDE",
@@ -1145,39 +675,29 @@
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   {
     "chemical": "POLYSACCHARIDES",
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   {
     "chemical": "LACTIC-ACID",
-    "plant_species": "Ammi visnaga",
+    "plant_species": "Nicotiana tabacum",
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   {
     "chemical": "(-)-INOSITOL",
@@ -1185,9 +705,9 @@
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   {
     "chemical": "GLYCOPROTEINS",
@@ -1195,69 +715,39 @@
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   {
     "chemical": "HISTIDINE",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Calathea allouia",
     "application": "Antiarteriosclerotic",
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   {
     "chemical": "GLOBULIN",
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     "dosage": null,
     "pubmed_mentions_2026": 48451,
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   {
     "chemical": "CHOLINE",
-    "plant_species": "Abrus precatorius",
+    "plant_species": "Urtica dioica",
     "application": "Antialzheimeran",
     "dosage": "5-16 g/man/day",
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   {
     "chemical": "NUCLEIC-ACIDS",
@@ -1265,29 +755,29 @@
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   {
     "chemical": "CHLOROPHYLL",
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   {
     "chemical": "GLUTAMINE",
-    "plant_species": "Allium ampeloprasum",
+    "plant_species": "Lycium chinense",
     "application": "Antialcoholic",
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     "chemical": "AMINES",
@@ -1295,69 +785,69 @@
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   {
     "chemical": "LIPASE",
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   {
     "chemical": "PHENYLALANINE",
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     "application": "AntiADD",
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   {
     "chemical": "LECTIN",
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   {
     "chemical": "ALDEHYDES",
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   {
     "chemical": "COCAINE",
-    "plant_species": "Erythroxylum amazonicum",
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     "application": "Anesthetic",
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   {
     "chemical": "EPINEPHRINE",
-    "plant_species": "Crataegus laevigata",
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     "application": "Adrenergic",
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     "chemical": "ASCORBIC",
@@ -1365,49 +855,49 @@
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   {
     "chemical": "PHENOL",
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   {
     "chemical": "ARACHIDONIC-ACID",
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   {
     "chemical": "INOSITOL",
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     "application": "Antialopecic",
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   {
     "chemical": "ASCORBIC-ACID",
-    "plant_species": "Abelmoschus esculentus",
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     "application": "Acidulant",
     "dosage": "FEMA 6,000",
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     "chemical": "PACLITAXEL",
@@ -1415,69 +905,39 @@
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   {
     "chemical": "URIC-ACID",
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   {
     "chemical": "GUANINE",
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+    "plant_species": "Beta vulgaris subsp. subsp. vulgaris",
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   {
     "chemical": "PYRIDINE",
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+    "plant_species": "Centella asiatica",
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   {
     "chemical": "PHORBOL",
@@ -1485,29 +945,9 @@
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     "chemical": "ALANINE-AMINOTRANSFERASE",
@@ -1515,19 +955,19 @@
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   {
     "chemical": "AMYLASE",
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   {
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@@ -1535,29 +975,29 @@
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+    "patent_count_since_2020": 8
   },
   {
     "chemical": "L-ARGININE",
-    "plant_species": "Eriobotrya japonica",
+    "plant_species": "Malus domestica",
     "application": "ACE-Inhibitor",
     "dosage": "500 mg/kg ivn adult hmn",
     "pubmed_mentions_2026": 37703,
-    "clinical_trials_count_2026": 24,
-    "chembl_bioactivity_count": 474,
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+    "chembl_bioactivity_count": 167,
+    "patent_count_since_2020": 74
   },
   {
     "chemical": "INDOLE",
-    "plant_species": "Brassica oleracea var. gongylodes",
+    "plant_species": "Zea mays",
     "application": "Anticariogenic",
     "dosage": "MIC=800 ug/ml",
     "pubmed_mentions_2026": 37693,
-    "clinical_trials_count_2026": 35,
-    "chembl_bioactivity_count": 185,
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+    "chembl_bioactivity_count": 91,
+    "patent_count_since_2020": 174
   },
   {
     "chemical": "ACID-PHOSPHATASE",
@@ -1565,9 +1005,9 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 37488,
-    "clinical_trials_count_2026": 37,
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 0
   },
   {
     "chemical": "DIPHENYL",
@@ -1575,19 +1015,19 @@
     "application": "CNS-Depressant",
     "dosage": null,
     "pubmed_mentions_2026": 37369,
-    "clinical_trials_count_2026": 12,
-    "chembl_bioactivity_count": 462,
-    "patent_count_since_2020": 12
+    "clinical_trials_count_2026": 0,
+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 158
   },
   {
     "chemical": "CAFFEINE",
-    "plant_species": "Annona cherimola",
+    "plant_species": "Theobroma bicolor",
     "application": "Analeptic",
     "dosage": "200 scu mus",
     "pubmed_mentions_2026": 36416,
-    "clinical_trials_count_2026": 12,
-    "chembl_bioactivity_count": 62,
-    "patent_count_since_2020": 2
+    "clinical_trials_count_2026": 437,
+    "chembl_bioactivity_count": 2999,
+    "patent_count_since_2020": 83
   },
   {
     "chemical": "CYCLIC-AMP",
@@ -1595,29 +1035,19 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 36413,
-    "clinical_trials_count_2026": 4,
-    "chembl_bioactivity_count": 404,
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 1
   },
   {
     "chemical": "POLYPHENOLS",
-    "plant_species": "Allium ampeloprasum",
+    "plant_species": "Arctium lappa",
     "application": "Anthelmintic",
     "dosage": null,
     "pubmed_mentions_2026": 36264,
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-  },
-  {
-    "chemical": "CHROMIUM",
-    "plant_species": "Achillea millefolium",
-    "application": "Amphiglycemic?",
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-    "clinical_trials_count_2026": 24,
-    "chembl_bioactivity_count": 374,
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 89
   },
   {
     "chemical": "ADENOSINE-DIPHOSPHATE",
@@ -1625,39 +1055,29 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 36023,
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-  {
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   },
   {
     "chemical": "PHOSPHODIESTERASE",
-    "plant_species": "Capsicum annuum",
+    "plant_species": "Triticum aestivum",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 34822,
-    "clinical_trials_count_2026": 16,
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 129
   },
   {
     "chemical": "MELATONIN",
-    "plant_species": "Allium cepa",
+    "plant_species": "Scutellaria baicalensis",
     "application": "Anaphrodisiac",
     "dosage": null,
     "pubmed_mentions_2026": 34598,
-    "clinical_trials_count_2026": 26,
-    "chembl_bioactivity_count": 26,
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+    "chembl_bioactivity_count": 1755,
+    "patent_count_since_2020": 105
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   {
     "chemical": "HYDROLASE",
@@ -1665,39 +1085,39 @@
     "application": null,
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     "pubmed_mentions_2026": 34110,
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+    "patent_count_since_2020": 164
   },
   {
     "chemical": "CALMODULIN",
-    "plant_species": "Hordeum vulgare",
+    "plant_species": "Zea mays",
     "application": "Cancer-Preventive",
     "dosage": null,
     "pubmed_mentions_2026": 33983,
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 19
   },
   {
     "chemical": "MANNOSE",
-    "plant_species": "Abies spectabilis",
+    "plant_species": "Capsella bursa-pastoris",
     "application": "Anticystitic",
     "dosage": "0.25-1 tsp 3-4 x/day orl man",
     "pubmed_mentions_2026": 33977,
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+    "chembl_bioactivity_count": 40,
+    "patent_count_since_2020": 98
   },
   {
     "chemical": "VITAMIN-E",
-    "plant_species": "Angelica sinensis",
+    "plant_species": "Capparis spinosa",
     "application": "Circulatory-Stimulant",
     "dosage": null,
     "pubmed_mentions_2026": 33916,
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   {
     "chemical": "FOLATE",
@@ -1705,9 +1125,9 @@
     "application": null,
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     "pubmed_mentions_2026": 33682,
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   {
     "chemical": "DECARBOXYLASE",
@@ -1715,19 +1135,9 @@
     "application": null,
     "dosage": null,
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-    "application": "Allergenic",
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-    "clinical_trials_count_2026": 5,
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+    "chembl_bioactivity_count": 0,
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   },
   {
     "chemical": "(+)-VALINE",
@@ -1735,29 +1145,29 @@
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 33441,
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   },
   {
     "chemical": "PROTEINASE",
-    "plant_species": "Aloe vera",
+    "plant_species": "Carica papaya",
     "application": null,
     "dosage": null,
     "pubmed_mentions_2026": 32640,
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+    "patent_count_since_2020": 32
   },
   {
     "chemical": "BIOTIN",
-    "plant_species": "Allium sativum var. sativum",
+    "plant_species": "Panax ginseng",
     "application": "Antialopecic",
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     "pubmed_mentions_2026": 32594,
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+    "chembl_bioactivity_count": 176,
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   {
     "chemical": "PURINE",
@@ -1765,19 +1175,19 @@
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     "pubmed_mentions_2026": 32579,
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   },
   {
     "chemical": "ATROPINE",
-    "plant_species": "Anisodus tanguticus",
+    "plant_species": "Solanum dulcamara",
     "application": "Allergenic",
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     "pubmed_mentions_2026": 32096,
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+    "chembl_bioactivity_count": 1253,
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   {
     "chemical": "OXYGENASE",
@@ -1785,9 +1195,9 @@
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   {
     "chemical": "VITAMIN-C",
@@ -1795,19 +1205,19 @@
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   },
   {
     "chemical": "QUERCETIN",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Drimys winteri",
     "application": "5-Lipoxygenase-Inhibitor",
     "dosage": "IC50 (uM)=4",
     "pubmed_mentions_2026": 31310,
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+    "chembl_bioactivity_count": 2871,
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   {
     "chemical": "LYSOZYME",
@@ -1815,9 +1225,9 @@
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     "pubmed_mentions_2026": 31264,
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   {
     "chemical": "MUCIN",
@@ -1825,49 +1235,39 @@
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     "pubmed_mentions_2026": 30716,
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   },
   {
     "chemical": "GAMMA-AMINOBUTYRIC-ACID",
-    "plant_species": "Ananas comosus",
+    "plant_species": "Humulus lupulus",
     "application": "Analeptic",
     "dosage": null,
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-    "application": "Androgenic",
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-    "clinical_trials_count_2026": 49,
-    "chembl_bioactivity_count": 149,
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   },
   {
     "chemical": "NICOTINAMIDE",
-    "plant_species": "Agrimonia eupatoria",
+    "plant_species": "Linum usitatissimum",
     "application": "Cancer-Preventive",
     "dosage": null,
     "pubmed_mentions_2026": 29683,
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   },
   {
     "chemical": "VITAMIN-A",
-    "plant_species": "Angelica sinensis",
+    "plant_species": "Medicago sativa subsp. sativa",
     "application": null,
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     "pubmed_mentions_2026": 29643,
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   {
     "chemical": "OLIGOSACCHARIDES",
@@ -1875,9 +1275,9 @@
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     "pubmed_mentions_2026": 29592,
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   {
     "chemical": "CARBOXYLIC-ACID",
@@ -1885,29 +1285,29 @@
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   },
   {
     "chemical": "GLUTAMIC-ACID",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Nigella sativa",
     "application": "Antialkali?",
     "dosage": "500-1,000 mg/day/orl/man",
     "pubmed_mentions_2026": 28787,
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   },
   {
     "chemical": "FOLIC-ACID",
-    "plant_species": "Achillea millefolium",
+    "plant_species": "Juglans regia",
     "application": "AntiSpina-Bifida",
     "dosage": null,
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   {
     "chemical": "ALKALOID",
@@ -1915,19 +1315,19 @@
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   },
   {
     "chemical": "GUANOSINE",
-    "plant_species": "Allium sativum var. sativum",
+    "plant_species": "Cucurbita pepo",
     "application": null,
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     "pubmed_mentions_2026": 27801,
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   {
     "chemical": "GLYCOSIDES",
@@ -1935,59 +1335,29 @@
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   },
   {
     "chemical": "CURCUMIN",
-    "plant_species": "Costus speciosus",
+    "plant_species": "Curcuma longa",
     "application": "5-Lipoxygenase-Inhibitor",
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   {
     "chemical": "QUINONE",
-    "plant_species": "Aloe vera",
+    "plant_species": "Vitex agnus-castus",
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   {
     "chemical": "ADENOSINE-TRIPHOSPHATE",
@@ -1995,29 +1365,9 @@
     "application": "Antienzymatic",
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   {
     "chemical": "BETA-GALACTOSIDASE",
@@ -2025,29 +1375,19 @@
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   {
     "chemical": "ESTERASE",
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@@ -2055,29 +1395,19 @@
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   {
     "chemical": "FLUORINE",
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@@ -2085,19 +1415,19 @@
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   {
     "chemical": "D-GLUCOSE",
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     "chemical": "(-)-DI-O-METHYL-THUJAPLICATIN METHYL ETHER",
@@ -2105,39 +1435,29 @@
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     "chemical": "CHLORINE",
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   {
     "chemical": "GLUCOSIDASE",
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@@ -2145,9 +1465,9 @@
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@@ -2155,9 +1475,9 @@
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@@ -2165,69 +1485,69 @@
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     "chemical": "5-HYDROXYTRYPTAMINE",
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     "chemical": "(+)-CATECHOL",
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@@ -2235,19 +1555,9 @@
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@@ -2255,19 +1565,9 @@
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@@ -2275,19 +1575,19 @@
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@@ -2375,9 +1675,9 @@
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@@ -2415,9 +1715,9 @@
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@@ -2505,9 +1805,9 @@
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   {
     "chemical": "RIBONUCLEIC-ACID",
@@ -2515,9 +1815,9 @@
     "application": "Antiasthenic",
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     "chemical": "(-)-CATECHIN",
@@ -2525,9 +1825,9 @@
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   {
     "chemical": "CARNITINE",
@@ -2535,19 +1835,19 @@
     "application": "Antianginal",
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   {
     "chemical": "XANTHINE",
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+    "plant_species": "Oryza sativa",
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   {
     "chemical": "URIDINE",
@@ -2555,49 +1855,39 @@
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   {
     "chemical": "COLCHICINE",
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   {
     "chemical": "ORGANIC-ACIDS",
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   {
     "chemical": "ORNITHINE",
-    "plant_species": "Allium sativum var. sativum",
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     "chemical": "LIPOXYGENASE",
@@ -2605,9 +1895,9 @@
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     "chemical": "IRON-OXIDE",
@@ -2615,18 +1905,18 @@
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   {
     "chemical": "CITRIC-ACID",
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@@ -2635,9 +1925,9 @@
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   {
     "chemical": "(+)-ABSCISIC-ACID",
@@ -2645,39 +1935,39 @@
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   {
     "chemical": "ABSCISIC-ACID",
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   {
     "chemical": "SALICYLIC-ACID",
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   {
     "chemical": "THEOPHYLLINE",
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     "chemical": "ASPARTIC-ACID",
@@ -2686,8 +1976,8 @@
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     "chemical": "GLUCAN",
@@ -2695,19 +1985,19 @@
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   {
     "chemical": "LECTINS",
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     "chemical": "AUXIN",
@@ -2715,49 +2005,49 @@
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   {
     "chemical": "BETA-CAROTENE",
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   {
     "chemical": "ALPHA-TOCOPHEROL",
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   {
     "chemical": "GLUTEN",
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   {
     "chemical": "OXALATE",
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     "chemical": "LACTONE",
@@ -2765,9 +2055,9 @@
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     "chemical": "OUABAIN",
@@ -2775,9 +2065,9 @@
     "application": "Antiarrhythmic",
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     "chemical": "CARBOXYLASE",
@@ -2785,49 +2075,49 @@
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   {
     "chemical": "PHENOLICS",
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   {
     "chemical": "CATECHOL",
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   {
     "chemical": "ALKANES",
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   {
     "chemical": "CARBONIC-ANHYDRASE",
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     "chemical": "PUFA",
@@ -2835,9 +2125,9 @@
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     "chemical": "NAPHTHALENE",
@@ -2845,19 +2135,19 @@
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   {
     "chemical": "RIBONUCLEASE",
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     "chemical": "ALPHA-AMYLASE",
@@ -2865,9 +2155,9 @@
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@@ -2875,9 +2165,9 @@
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@@ -2895,9 +2185,9 @@
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@@ -2905,119 +2195,89 @@
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     "chemical": "ASPARAGINE",
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   {
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   {
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     "chemical": "ISOLEUCINE",
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     "chemical": "STYRENE",
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   {
     "chemical": "COUMARIN",
-    "plant_species": "Acacia farnesiana",
+    "plant_species": "Cinnamomum verum",
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   {
     "chemical": "HYDROXYPROLINE",
-    "plant_species": "Aloe vera",
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   {
     "chemical": "SILICATE",
@@ -3025,9 +2285,9 @@
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   {
     "chemical": "DIACYLGLYCEROL",
@@ -3035,9 +2295,9 @@
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     "chemical": "AFLATOXIN",
@@ -3045,19 +2305,9 @@
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   {
     "chemical": "TRIACYLGLYCEROL",
@@ -3065,9 +2315,9 @@
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     "chemical": "COAGULASE",
@@ -3075,49 +2325,39 @@
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   {
     "chemical": "PHOSPHORYLASE",
-    "plant_species": "Solanum tuberosum",
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   {
     "chemical": "ANTHRACENE",
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   {
     "chemical": "CHLOROPHYLL-A",
-    "plant_species": "Avena sativa",
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     "chemical": "ANTHOCYANINS",
@@ -3125,49 +2365,39 @@
     "application": "Antimyopic",
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   {
     "chemical": "ALCOHOL-DEHYDROGENASE",
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   {
     "chemical": "UREASE",
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   {
     "chemical": "GLUCOSE-6-PHOSPHATE-DEHYDROGENASE",
-    "plant_species": "Erythroxylum coca var. coca",
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     "chemical": "CARBOXYLIC-ACIDS",
@@ -3175,29 +2405,29 @@
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   {
     "chemical": "ANTHOCYANIN",
-    "plant_species": "Fragaria spp",
+    "plant_species": "Parthenocissus quinquefolia",
     "application": "Antiviral",
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   {
     "chemical": "L-DOPA",
-    "plant_species": "Cytisus scoparius",
+    "plant_species": "Euphorbia lathyris",
     "application": "Analgesic",
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@@ -3205,9 +2435,9 @@
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     "chemical": "GLUTATHIONE-REDUCTASE",
@@ -3215,98 +2445,58 @@
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   {
     "chemical": "SAPONINS",
-    "plant_species": "Achillea millefolium",
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     "application": "Antihepatomic",
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   {
     "chemical": "PALMITIC-ACID",
-    "plant_species": "Abelmoschus esculentus",
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     "application": "Antifibrinolytic",
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   {
     "chemical": "URACIL",
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   {
     "chemical": "RIBOFLAVIN",
-    "plant_species": "Abelmoschus esculentus",
+    "plant_species": "Avena sativa",
     "application": "Antiarabiflavinotic",
     "dosage": "2-10 mg/day orl",
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   {
     "chemical": "HYDROGEN-SULFIDE",
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   {
     "chemical": "GALLIC-ACID",
-    "plant_species": "Abrus precatorius",
+    "plant_species": "Euphorbia hirta",
     "application": "ACE-Inhibitor",
     "dosage": "IC50=7.7 mM/l",
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   {
     "chemical": "BIPHENYL",
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   {
     "chemical": "THIAMINE",
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   {
     "chemical": "TYROSINASE",
-    "plant_species": "Allium sativum var. sativum",
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     "application": "Antihypertensive",
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@@ -3365,9 +2555,9 @@
     "application": "Pyrogenic",
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   {
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@@ -3375,9 +2565,9 @@
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   {
     "chemical": "UNSATURATED-FATTY-ACIDS",
@@ -3385,19 +2575,19 @@
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   {
     "chemical": "GENISTEIN",
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   {
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@@ -3405,39 +2595,39 @@
     "application": "Abortifacient",
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   {
-    "chemical": "L-(+)-LYSINE",
-    "plant_species": "Aesculus hippocastanum",
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   },
   {
-    "chemical": "L-LYSINE",
-    "plant_species": "Plantago ovata",
+    "chemical": "L-(+)-LYSINE",
+    "plant_species": "Aesculus hippocastanum",
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   {
     "chemical": "STEROLS",
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     "chemical": "BETA-GLUCURONIDASE",
@@ -3445,19 +2635,19 @@
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   {
     "chemical": "ANILINE",
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   {
     "chemical": "ALLYL",
@@ -3465,9 +2655,9 @@
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@@ -3475,59 +2665,49 @@
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   {
     "chemical": "LINOLENIC-ACID",
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   {
     "chemical": "PHYTOHEMAGGLUTININ",
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   {
     "chemical": "LECITHIN",
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+    "plant_species": "Polygonum multiflorum",
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   {
     "chemical": "NICOTINIC-ACID",
-    "plant_species": "Alisma plantago-aquatica",
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     "application": "AntiCrohn's",
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     "chemical": "(FUNGICIDE)",
@@ -3535,9 +2715,9 @@
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     "chemical": "24(28)-DEHYDRO-MAKISTERONE A",
@@ -3545,19 +2725,19 @@
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   {
     "chemical": "CYSTINE",
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     "chemical": "QUINOLINE",
@@ -3565,9 +2745,9 @@
     "application": "Antimalarial",
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     "chemical": "EICOSAPENTAENOIC-ACID",
@@ -3575,39 +2755,29 @@
     "application": "Antiarthritic",
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   {
     "chemical": "GUANIDINE",
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     "chemical": "SPHINGOMYELIN",
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@@ -3615,19 +2785,9 @@
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@@ -3635,29 +2795,29 @@
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   {
     "chemical": "BENZOIC-ACID",
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   {
     "chemical": "SORBITOL",
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     "chemical": "(+)-EPIGALLOCATECHIN",
@@ -3665,49 +2825,49 @@
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   {
     "chemical": "CELLULASE",
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   {
     "chemical": "(-)-EPIGALLOCATECHIN",
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   {
     "chemical": "GLYCOLIC-ACID",
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   {
     "chemical": "BUTYRIC-ACID",
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     "chemical": "SATURATED-FATTY-ACIDS",
@@ -3715,9 +2875,9 @@
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     "chemical": "CYTOCHROME-OXIDASE",
@@ -3725,39 +2885,39 @@
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     "chemical": "PYRROLE",
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   {
     "chemical": "PENTOSE",
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     "chemical": "HYPOXANTHINE",
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@@ -3765,9 +2925,9 @@
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@@ -3775,19 +2935,19 @@
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@@ -3795,49 +2955,49 @@
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     "chemical": "INULIN",
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   {
     "chemical": "CATECHIN",
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     "chemical": "EPIGALLOCATECHIN",
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   {
     "chemical": "FUCOSE",
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@@ -3845,29 +3005,29 @@
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     "chemical": "SPERMIDINE",
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@@ -3875,19 +3035,9 @@
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@@ -3895,9 +3045,9 @@
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@@ -3905,49 +3055,49 @@
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     "chemical": "SPERMINE",
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+    "chembl_bioactivity_count": 0,
+    "patent_count_since_2020": 42
   },
   {
     "chemical": "ANDROSTENEDIONE",
-    "plant_species": "Pinus sylvestris",
+    "plant_species": "Vitex agnus-castus",
     "application": "Androgenic",
     "dosage": null,
     "pubmed_mentions_2026": 10375,
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   {
     "chemical": "QUININE",
@@ -3955,19 +3105,19 @@
     "application": "Abortifacient",
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     "pubmed_mentions_2026": 10345,
-    "clinical_trials_count_2026": 46,
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   },
   {
     "chemical": "PHOSPHORIC-ACID",
-    "plant_species": "Calea zacatechichi",
+    "plant_species": "Rehmannia glutinosa",
     "application": "Acidulant",
     "dosage": null,
     "pubmed_mentions_2026": 10299,
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+    "chembl_bioactivity_count": 0,
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   },
   {
     "chemical": "APOMORPHINE",
@@ -3975,9 +3125,9 @@
     "application": "Antialcoholic",
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     "pubmed_mentions_2026": 10284,
-    "clinical_trials_count_2026": 26,
-    "chembl_bioactivity_count": 126,
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+    "clinical_trials_count_2026": 37,
+    "chembl_bioactivity_count": 1068,
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   },
   {
     "chemical": "VINBLASTINE",
@@ -3985,9 +3135,9 @@
     "application": "AntiHodgkin's",
     "dosage": null,
     "pubmed_mentions_2026": 10246,
-    "clinical_trials_count_2026": 41,
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+    "chembl_bioactivity_count": 2619,
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   },
   {
     "chemical": "PAPAIN",
@@ -3995,8 +3145,858 @@
     "application": "Allergenic",
     "dosage": null,
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+  },
+  {
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+    "plant_species": "Pelargonium graveolens",
+    "application": "FLavor",
+    "dosage": "FEMA 1-36,000",
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+  },
+  {
+    "chemical": "KAEMPFEROL",
+    "plant_species": "Melilotus officinalis",
+    "application": "11B-HSD-Inhibitor",
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+    "plant_species": "Erythroxylum coca var. coca",
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+  {
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+  },
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+  },
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+  },
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+  },
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+  },
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+  },
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   }
 ]
\ No newline at end of file