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Meta_variable_description.csv
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Variable Name,Description
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geo_accession,GEO sample accession number (GSM).
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ID,Subject identifier within one study (unique per participant); useful when aligning with antibody raw data.
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study_ID,Study or cohort identifier
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tissue,"Sample source (e.g., whole blood, PBMC, nasal swab)."
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platform,"Gene expression platform used (e.g., RNA-seq, microarray, scRNA-seq)."
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pathogen,"Infectious agent studied (e.g., SARS-CoV-2, influenza)."
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batch,Technical or experimental batch ID within one study
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title,Sample title from GEO metadata.
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timepoint,Exact time or day post-vaccination/infection.
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timepoint_group,Categorical grouping of timepoints
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infection_group,"Infection status grouping (e.g., infected vs. uninfected); represents the outcome in inoculation studies."
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symptom_group,"Symptom severity group (e.g., symptomatic vs. asymptomatic); represents the outcome in inoculation studies."
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symptom_group_original,Original symptom classification from source study.
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Total_DSS,Disease Severity Score (quantitative summary of symptoms).
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MFC,Maximum fold change (MFC)
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responder,"Indicator of vaccine response (e.g., responder, moderate responder, or non-responder), defined based on Maximum Fold Change (MFC)."
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responder_original,Original response classification before harmonization.
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study_group,"Group assignment within a study (e.g., vaccine arm, control)."
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Enrollment_year,Year when participant enrolled in the study.
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vaccine,"Vaccine type (e.g., mRNA-1273, BNT162b2)."
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vaccine_dose,"Vaccine dose number (e.g., 1st, 2nd, 3rd)."
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sex,Biological sex (Male/Female).
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age,Participant age in years.
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age_group,"Age category (e.g., 18–30, 31–50, >50)."
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immport_expsamp_acc,ImmPort experiment sample accession.
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Expsample.Accession,Alternate experimental sample accession in ImmPort
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ethnicity,"Participant ethnicity (e.g., Hispanic, non-Hispanic)."
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race,"Race as recorded in metadata (e.g., White, Asian, Black)."
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race_ethnicity,Combined race and ethnicity classification.
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sham,Indicator for sham or placebo treatment.
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BMI,Body Mass Index (kg/m²).
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PreviousCOVID19,Prior SARS-CoV-2 infection (Yes/No).
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symptom_group_previous_covid,Symptom group classification for previously infected individuals.
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UnderlyingDisease,Presence of underlying or chronic medical conditions.
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turbo_reatment,Indicator of whether the RNA sample was treated with TurboDNase (Thermo Fisher Scientific) to remove contaminating genomic DNA during RNA extraction. Marked as “Turbo Treated” if DNase treatment was applied.
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Medications,Medications taken by participant during study.
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side_effect,Reported vaccine side effects.
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Duration_of_symptoms,Duration (in days) of reported symptoms.
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days.since.covid.19.diagnosis,Days since COVID-19 diagnosis at time of sampling.
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Vaccinated.in.prior.3.seasons,Whether vaccinated in the prior three influenza seasons (Yes/No).
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influenza.vaccination.count..previous.10.years.,Number of influenza vaccinations received in the previous 10 years.
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Height_cm,Height in centimeters.
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Weight_kg,Weight in kilograms.
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Current.smoker,Current smoking status (Yes/No).
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Prior.smoker,Former smoking status (Yes/No).
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Sleep.apnea,Presence of sleep apnea (Yes/No).
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diabetes,Presence of diabetes (Yes/No).
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seroconversion,Binary or quantitative measure of antibody seroconversion.
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viral_shedding,Presence or level of viral shedding post-infection or vaccination.
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