accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
O13267
WNT5A_PLEWA
Protein Wnt-5a
Pleurodeles
<M><A><S><R><Y><L><T><L><A><A><A><L><L><A><S><F><L><Q><V><D><I><E><A><N><S><W><W><S><L><A><M><N><P><V><Q><I><P><E><A><Y><I><V><G><A><Q><P><L><C><S><Q><L><A><G><L><S><P><G><Q><K><K><L><C><Q><L><Y><Q><D><H><M><Q><Y><I><G><E><G><A><K><T><G><I><K><E><C><Q><Y><Q><F><R><H><R><R><W><N><C><S><T><V><D><N><I><S><V><F><G><R><V><M...
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis.<BOP>
O13267
Q65P74
TRUA_BACLD
tRNA-uridine isomerase I
Bacillus
<M><R><M><K><C><T><I><S><Y><D><G><H><L><F><Y><G><Y><Q><V><Q><P><G><Q><R><T><I><Q><D><E><L><E><K><A><L><Q><T><L><H><K><A><K><E><R><I><P><V><V><S><S><G><R><T><D><S><G><V><H><A><V><G><Q><T><I><H><F><D><S><P><L><S><I><P><E><A><K><W><P><Y><A><L><N><A><L><L><P><D><D><I><S><V><R><K><A><E><A><V><N><D><Q><F><H><A><R><F><S><A><K...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
Q65P74
Q9DBS2
TPRGL_MOUSE
Protein FAM79A
Mus
<M><L><Q><L><R><D><T><V><D><S><A><G><T><S><P><T><A><V><L><A><A><G><E><D><A><G><A><G><R><P><G><A><G><T><P><L><R><Q><T><L><W><P><L><N><V><H><D><P><T><R><R><A><R><V><K><E><Y><F><V><F><R><P><G><T><I><E><Q><A><V><E><E><I><R><A><V><V><R><P><V><E><D><G><E><I><Q><G><V><W><L><L><T><E><V><D><H><W><N><N><E><K><E><R><L><V><L><V><T...
Presynaptic protein involved in the synaptic transmission tuning. Regulates synaptic release probability by decreasing the calcium sensitivity of release.<BOP>
Q9DBS2
Q40289
UFOG7_MANES
UDP-glucose flavonoid 3-O-glucosyltransferase 7
Manihot
<T><L><N><L><I><P><G><M><S><K><I><Q><I><R><D><L><P><E><G><V><L><F><G><N><L><E><S><L><F><S><Q><M><L><H><N><M><G><R><M><L><P><R><A><A><A><V><L><M><N><S><F><E><E><L><D><P><T><I><V><S><D><L><N><S><K><F><N><N><I><L><C><I><G><P><F><N><L><V><S><P><P><P><P><V><P><D><T><Y><G><C><M><A><W><L><D><K><Q><K><P><A><S><V><A><Y><I><S><F...
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.<BOP>
Q40289
A6WM46
TOLB_SHEB8
Tol-Pal system protein TolB
Shewanella
<M><R><I><L><A><K><W><L><A><L><A><V><L><L><C><T><T><P><A><K><A><A><L><D><I><V><I><T><E><G><V><D><A><A><R><P><I><A><V><M><P><F><V><W><Q><G><P><G><A><A><P><Q><A><I><A><D><V><V><M><S><D><L><V><R><S><G><T><F><K><P><L><D><E><L><G><L><P><Q><R><N><I><G><T><V><A><Q><F><Q><A><N><S><W><S><S><V><G><A><E><A><L><V><L><G><T><V><K><P...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
A6WM46
A4Y3A9
Y712_SHEPC
Nucleotide-binding protein Sputcn32_0712
Shewanella
<M><K><L><V><I><V><S><G><R><S><G><S><G><K><S><V><A><L><R><V><L><E><D><L><G><Y><Y><C><V><D><N><L><P><L><P><L><I><G><S><L><L><E><Q><L><K><G><S><N><D><L><V><A><I><S><V><D><V><R><N><M><P><E><Q><D><K><V><L><V><Q><Q><L><S><N><L><P><A><G><T><E><I><T><S><F><F><L><N><S><S><D><K><V><L><L><K><R><Y><S><E><T><R><R><L><H><P><L><S><K...
Displays ATPase and GTPase activities.<BOP>
A4Y3A9
A1JJ98
TYPH_YERE8
TdRPase
Yersinia
<M><F><L><A><Q><E><I><I><R><K><K><R><D><G><Q><A><L><S><E><E><E><I><R><F><F><I><N><G><I><R><D><N><V><V><S><E><G><Q><I><A><A><L><A><M><T><I><Y><F><H><D><M><S><M><P><E><R><V><A><L><T><M><A><M><R><D><S><G><T><V><L><N><W><K><S><L><N><L><N><G><P><M><V><D><K><H><S><T><G><G><V><G><D><V><T><S><L><M><L><G><P><M><V><A><A><C><G><G...
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP>
A1JJ98
Q868G6
TACHY_APIME
Tachykinin-related peptide 7
Apis
<M><I><I><H><S><I><F><L><L><M><V><S><I><T><L><V><I><A><E><E><S><D><N><V><L><F><D><K><R><A><P><T><G><H><Q><E><M><Q><G><K><Q><N><S><A><S><L><N><S><E><N><F><G><I><F><K><R><A><L><M><G><F><Q><G><V><R><G><K><K><N><S><I><I><N><D><V><K><N><E><L><F><P><E><D><I><N><K><R><A><P><M><G><F><Q><G><M><R><G><K><K><A><S><F><D><D><E><Y><Y...
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Associated with sex-specific or age/division of labor-selective behavior and/or physiology of honeybees.<BOP>
Q868G6
B0TT74
UREG_SHEHH
Urease accessory protein UreG
Shewanella
<M><T><E><L><E><Y><K><Q><P><L><R><I><G><V><G><G><P><V><G><S><G><K><T><A><L><L><E><V><L><C><K><A><L><R><N><K><Y><Q><I><A><V><V><T><N><D><I><Y><T><Q><E><D><A><K><I><L><T><R><A><E><A><L><D><A><D><R><I><I><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><M><N><L><A><A><V><E><E><L><A><K><R><H><K><N><L><D><V><V><F><V><E><S...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B0TT74
P54402
TBG_EUPAE
Gamma-tubulin
Euplotes
<M><P><R><E><I><I><T><C><Q><V><G><Q><C><G><N><Q><I><G><M><E><F><W><K><Q><L><C><M><E><H><G><I><N><P><E><G><I><L><E><D><F><A><V><N><G><E><D><R><K><D><V><F><F><Y><Q><A><D><D><E><H><Y><V><P><R><A><V><L><I><D><L><E><P><R><V><I><N><C><I><Q><K><S><T><Y><S><S><L><Y><N><P><E><N><I><Y><I><A><K><H><G><G><G><A><G><N><N><W><G><R><G...
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.<BOP>
P54402
P33044
THHR_HORVU
Antifungal protein R
Hordeum
<A><T><I><T><V><V><N><R><C><S><Y><T><V><W><P><G><A><L><P><G><G><G><V><R><L><D><P><G><Q><R><W><A><L><N><M><P><A><G><T><A><G><A><A><V>
Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans.<BOP>
P33044
B4G535
TOTZ_DROPE
Protein Turandot Z
Sophophora
<M><S><R><L><I><H><L><S><F><V><L><A><L><L><A><C><L><T><G><T><I><S><A><N><P><I><D><D><D><R><D><R><L><N><Q><L><L><S><N><P><E><P><A><D><D><A><E><L><L><R><N><T><Q><E><A><I><A><L><Y><K><K><H><A><R><R><T><L><P><G><H><Q><V><E><L><D><L><D><R><D><I><R><A><F><E><T><E><N><L><T><V><D><G><L><P><I><Q><G><G><V><W><D><L><I><K><K><G><A...
A humoral factor that may play a role in stress tolerance.<BOP>
B4G535
Q0VTA7
UBIA_ALCBS
4-HB polyprenyltransferase
Alcanivorax
<M><F><A><F><V><E><Q><R><Y><P><T><L><W><P><Y><I><Q><L><M><R><L><D><R><P><I><G><T><L><L><L><L><W><P><T><L><W><A><V><W><I><A><G><A><G><T><P><S><L><T><V><I><V><V><F><F><L><G><V><V><I><M><R><A><A><G><C><V><I><N><D><F><A><D><R><N><F><D><G><D><V><E><R><T><Q><G><R><P><L><A><T><G><A><L><S><A><K><Q><A><L><A><L><F><G><G><L><G><L...
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-...
Q0VTA7
Q0VMA0
TATA_ALCBS
Sec-independent protein translocase protein TatA
Alcanivorax
<M><F><S><G><I><S><I><W><Q><L><L><I><L><L><A><I><V><V><L><L><F><G><T><K><K><L><R><N><I><G><G><D><L><G><G><A><V><K><G><F><K><S><A><M><K><D><G><E><D><E><Q><D><H><K><R><L><A><D><D><D><Q><P><Q><N><K><Q><D><A><E><Q><K><A><E><Q><E><K><D><K><A>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q0VMA0
Q08975
THI21_YEAST
Hydroxymethylpyrimidine phosphate kinase
Saccharomyces
<M><T><Y><S><T><V><N><I><N><T><P><P><P><Y><L><A><L><A><S><N><E><K><L><P><T><V><L><S><I><A><G><T><D><P><S><G><G><A><G><V><E><A><D><V><K><T><I><T><A><H><R><C><Y><A><M><T><C><I><T><A><L><N><A><Q><T><P><V><K><V><Y><S><I><N><N><T><P><K><E><V><V><S><Q><I><L><D><A><N><L><Q><D><M><K><C><D><V><I><K><T><G><M><L><T><T><A><A><I><E...
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and also probably that of HMP to HMP-P.<BOP>
Q08975
Q2SRU7
TRMD_MYCCT
tRNA [GM37] methyltransferase
Mycoplasma
<M><K><F><S><I><I><T><L><F><P><K><I><I><N><S><Y><I><E><E><S><I><I><K><R><A><I><N><K><Q><A><I><Q><I><E><I><I><D><L><R><N><F><S><T><L><N><H><N><Q><V><D><D><Y><Q><Y><G><G><G><S><G><M><V><L><M><I><E><P><L><I><K><A><I><E><S><V><K><T><T><K><S><I><V><L><L><T><T><P><Q><G><K><T><L><N><Q><S><I><V><K><T><Y><S><N><N><Y><E><H><I><I...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q2SRU7
A3MV36
TBP_PYRCJ
TATA-box factor
Pyrobaculum
<M><S><S><K><G><P><S><Y><R><I><E><N><I><V><A><T><V><N><L><G><V><E><L><D><L><E><S><L><A><E><R><L><P><M><A><E><Y><N><P><D><Q><F><P><G><L><I><L><R><L><T><K><P><R><I><S><A><L><I><F><R><T><G><K><M><V><C><T><G><A><K><N><E><E><D><L><K><N><A><V><R><A><L><V><K><L><L><N><D><H><G><A><E><V><P><F><D><P><E><V><Q><I><Q><N><I><V><A><S...
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.<BOP>
A3MV36
Q8CQ77
TARI_STAES
Ribitol-5-phosphate cytidylyltransferase
Staphylococcus
<M><I><Y><A><G><I><L><A><G><G><I><G><S><R><M><G><N><V><P><L><P><K><Q><F><L><S><L><Q><G><K><P><I><I><I><H><T><V><E><K><F><L><M><Y><K><D><F><D><E><I><I><I><A><T><P><Q><K><W><I><N><Y><M><L><D><L><L><N><N><Y><Q><L><D><D><K><K><I><K><V><I><Q><G><G><D><D><R><N><H><S><I><M><N><I><I><E><S><I><E><Q><H><K><K><L><N><D><E><D><I><I...
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP>
Q8CQ77
B0TPX8
TOLB_SHEHH
Tol-Pal system protein TolB
Shewanella
<M><K><I><F><G><K><W><L><L><V><T><L><L><I><C><S><M><P><V><K><A><A><L><D><I><V><I><T><E><G><I><D><A><A><R><P><I><A><V><I><P><F><V><W><Q><G><T><G><P><M><P><S><Q><I><S><D><V><V><M><S><D><L><A><R><S><G><T><F><S><P><A><D><E><L><S><L><P><Q><R><G><I><S><T><L><A><Q><F><N><A><S><A><W><M><T><Q><P><A><E><A><V><V><M><G><S><I><K><P...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
B0TPX8
Q2SQW8
TSAC_HAHCH
tRNA threonylcarbamoyladenosine biosynthesis protein TsaC
Hahella
<M><S><A><W><F><I><Q><K><A><V><S><V><L><S><R><G><G><V><L><A><Y><P><T><E><A><V><W><G><L><G><C><D><P><S><C><E><D><A><V><N><R><I><L><Q><L><K><R><R><P><W><R><K><G><L><I><L><V><S><G><Q><I><E><H><F><S><Q><L><L><D><R><L><P><Q><Q><Q><K><D><Q><I><L><A><T><W><P><G><P><V><T><W><V><V><P><D><P><G><V><Y><A><P><L><V><R><G><A><H><D><A...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP>
Q2SQW8
Q0BPX7
UVRC_GRABC
Excinuclease ABC subunit C
Granulibacter
<M><T><M><P><D><A><P><A><N><P><P><K><E><A><D><N><P><S><L><P><I><V><E><A><P><P><G><K><G><V><T><V><I><E><A><M><L><K><L><L><P><D><R><P><G><V><Y><R><M><L><D><G><Q><G><E><A><L><Y><V><G><K><A><R><S><L><K><K><R><V><A><S><Y><T><Q><I><H><R><L><P><E><R><L><R><R><M><V><S><E><T><V><S><M><E><I><V><T><T><H><T><E><A><E><A><L><L><L><E...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q0BPX7
Q9LKI8
TBB_THAWE
Beta-tubulin
Conticribra
<M><R><E><I><V><H><I><Q><G><G><Q><C><G><N><Q><I><G><A><K><F><W><E><V><M><S><D><E><H><G><V><D><P><T><G><T><Y><H><G><D><S><D><L><Q><L><E><R><I><N><V><Y><F><N><E><A><T><G><G><R><Y><V><P><R><A><I><L><M><D><L><E><P><G><T><M><D><S><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><V><F><G><Q><T><G><A><G><N><N><W><A><K><G><H><Y><T...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
Q9LKI8
C0QWM9
TYSY_BRAHW
Thymidylate synthase
Brachyspira
<M><Q><N><Y><L><D><L><L><K><K><V><L><E><E><G><E><E><T><K><D><R><T><G><V><G><T><R><R><I><F><G><P><Q><L><R><F><K><F><E><G><N><K><I><P><I><I><T><T><K><R><V><F><M><K><G><V><I><I><E><L><L><W><F><L><Q><G><S><T><N><I><K><F><L><L><E><N><N><V><H><I><W><D><E><W><A><D><D><M><G><E><L><G><P><V><Y><G><K><Q><W><R><A><W><E><T><K><E><G...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
C0QWM9
D2BJS8
TATC_DEHMV
Sec-independent protein translocase protein TatC
Dehalococcoides
<M><S><S><K><N><E><T><P><E><V><E><E><E><E><P><P><E><E><A><K><A><K><G><K><M><P><I><G><G><H><F><N><E><L><R><Q><R><F><T><R><G><I><I><A><L><V><M><G><V><M><V><A><F><F><F><A><T><P><I><I><G><F><L><T><A><P><G><G><P><D><F><K><P><A><Q><L><G><V><M><E><Y><A><S><V><F><F><N><V><S><L><W><A><G><F><I><I><A><S><P><Y><I><L><Y><Q><L><I><A...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.<BOP>
D2BJS8
Q3KQE5
T38BA_XENLA
Transmembrane protein 38B-A
Xenopus
<M><E><S><L><S><E><L><S><V><Q><F><S><Q><L><S><M><F><P><F><F><D><M><A><H><Y><V><V><S><V><M><S><A><R><E><Q><A><G><A><L><D><I><A><A><R><S><P><M><A><S><W><F><S><A><M><L><Y><C><F><G><G><G><I><L><S><S><I><L><L><A><E><P><P><I><A><V><L><S><N><T><T><N><I><M><L><A><S><T><I><W><Y><M><V><Y><Y><F><P><Y><D><L><F><Y><N><C><F><F><F><L...
Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.<BOP>
Q3KQE5
Q83II9
ULAA_SHIFL
Ascorbate-specific permease IIC component UlaA
Shigella
<M><E><I><L><Y><N><I><F><T><V><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><D><R><M><G><D><A><Y><S><W><V><G><Y><A...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP...
Q83II9
A0L833
TATC_MAGMM
Sec-independent protein translocase protein TatC
Magnetococcus
<M><N><L><D><V><E><Q><K><A><P><L><V><E><H><L><I><E><L><R><N><R><L><M><I><S><V><G><A><I><I><V><G><F><I><L><C><Y><S><F><S><E><Q><I><F><E><F><L><A><A><P><L><H><E><I><L><G><P><Q><A><K><M><I><Y><T><A><L><H><E><A><F><F><T><Q><I><K><V><S><F><F><A><G><L><F><L><A><M><P><V><L><F><T><Q><M><W><L><F><I><A><P><G><L><Y><Q><H><E><R><S...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP>
A0L833
Q11HD9
TRMFO_CHESB
Folate-dependent tRNA(M-5-U54)-methyltransferase
unclassified Chelativorans
<M><T><T><K><P><I><H><V><I><G><G><G><L><A><G><S><E><A><A><W><Q><A><A><E><A><G><V><P><V><I><L><H><E><M><R><P><V><R><G><T><D><A><H><K><T><D><G><L><A><E><L><V><C><S><N><S><F><R><S><D><D><A><Q><T><N><A><V><G><L><L><H><A><E><M><R><L><A><G><S><L><I><M><R><A><G><D><A><N><Q><V><P><A><G><G><A><L><A><V><D><R><D><G><F><S><D><A><V...
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.<BOP>
Q11HD9
Q9XYU2
TCTP_PLAYO
Translationally-controlled tumor protein homolog
Plasmodium (Vinckeia)
<M><K><V><Y><K><D><I><F><T><N><D><E><V><C><S><D><S><Y><I><Q><E><D><P><F><G><N><P><E><F><R><E><I><A><F><E><V><K><S><N><K><R><I><K><G><N><D><D><Y><G><I><A><D><N><S><E><D><A><V><D><G><M><G><A><D><V><E><H><V><I><D><I><V><D><S><F><Q><L><T><S><T><S><L><S><K><K><E><Y><S><A><Y><V><K><N><F><M><Q><R><I><L><K><H><L><E><E><K><K><P...
Involved in calcium binding and microtubule stabilization.<BOP>
Q9XYU2
P85109
VSP1_GLOBR
Snake venom serine protease
Gloydius
<V><I><G><G><D><E><C><N><I><N><E><H><R><F><L><V><A><L><Y><H><S><R><S><R><T><F><L><C><G><G><T><L><I><N><Q><E><W><V><L><T><A><A><H><C><D><R><F><F><M><Y><I><R><L><G><M><H><N><K><N><V><N><F><D><D><E><Q><R><R><S><P><K><E><K><Y><F><F><R><C><S><N><N><F><T><K><W><D><K><D><I><M><L><I><R><L><D><S><P><V><N><N><S><A><H><I><A><P><L...
Thrombin-like snake venom serine protease. Cleaves bonds after Arg and Lys, converts fibrinogen (FGA and FGB) to fibrin and releases both fibrinopeptides A and B, and fibrinogen peptide Bbeta1-42. Has a blood clotting activity.<BOP>
P85109
Q8XXY2
TRPA_RALSO
Tryptophan synthase alpha chain
Ralstonia
<M><S><R><I><A><Q><T><F><S><Q><L><S><A><Q><G><R><K><G><L><I><P><F><I><T><A><G><D><P><Y><P><E><L><T><V><D><L><M><H><A><L><V><K><G><G><A><N><V><I><E><L><G><V><P><F><S><D><P><M><A><D><G><P><V><I><Q><R><A><S><E><R><A><L><A><K><K><I><G><L><R><T><V><L><D><Y><V><R><A><F><R><A><T><D><K><T><T><P><V><V><L><M><G><Y><A><N><P><I><E...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q8XXY2
A7NI03
TPIS_ROSCS
Triose-phosphate isomerase
Roseiflexus
<M><R><T><P><L><L><A><G><N><W><K><M><Y><K><T><T><G><E><A><R><E><L><V><E><G><L><L><H><G><L><G><D><V><G><D><R><K><V><L><V><C><P><P><F><T><A><L><Q><T><V><H><D><L><V><Q><G><T><P><I><A><L><G><A><Q><D><V><Y><I><E><P><Q><G><A><F><T><G><A><I><S><P><V><M><L><R><D><L><G><C><A><Y><V><I><V><G><H><S><E><R><R><A><I><F><G><E><G><D><E...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
A7NI03
Q3YS67
TSAD_EHRCJ
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Ehrlichia
<M><K><K><S><V><K><V><V><L><G><I><E><T><S><C><D><E><T><A><V><A><I><V><N><S><N><K><E><V><L><S><H><K><I><L><S><Q><K><E><H><A><E><Y><G><G><V><V><P><E><I><A><S><R><A><H><I><N><Y><L><Y><D><L><T><V><S><C><I><E><E><S><Q><L><S><L><N><N><I><D><A><V><A><V><T><S><G><P><G><L><I><G><G><L><I><V><G><V><M><I><A><K><G><I><A><S><V><T><G...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q3YS67
Q06493
YLH47_YEAST
LETM1 homolog
Saccharomyces
<M><L><K><Y><R><S><L><P><I><K><R><A><I><H><H><P><A><P><G><I><T><P><I><S><P><R><I><M><V><S><R><L><R><V><I><P><S><F><N><L><K><F><N><R><W><N><S><S><V><P><E><S><S><K><K><E><L><K><T><T><D><G><N><Q><E><S><A><S><K><V><S><P><V><K><E><K><E><K><V><P><F><K><V><K><M><Q><K><A><L><R><H><Y><W><D><G><S><K><L><L><G><L><E><I><K><I><S><S...
Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation.<BOP>
Q06493
Q39QN3
UVRC_GEOMG
Excinuclease ABC subunit C
Geobacter
<M><F><D><K><S><R><L><N><T><L><P><E><S><P><G><V><Y><L><M><K><G><S><D><G><T><I><L><Y><V><G><K><A><K><S><L><R><K><R><V><R><S><Y><F><G><A><A><G><E><S><R><Y><H><I><R><F><L><V><A><R><V><A><E><V><E><V><I><V><T><D><T><E><K><E><A><L><I><L><E><N><T><L><I><K><K><H><R><P><R><Y><N><L><D><L><R><D><D><K><T><Y><F><S><L><R><M><D><M><N...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
Q39QN3
B3DRW0
TPIS_BIFLD
Triose-phosphate isomerase
Bifidobacterium
<M><A><S><K><R><I><P><L><V><A><G><N><W><K><M><N><F><D><H><L><E><A><T><Y><F><V><Q><K><L><V><W><L><L><R><D><A><H><F><D><F><K><R><C><E><V><A><L><F><P><S><F><T><S><L><R><S><V><Q><V><L><V><E><A><D><K><L><H><V><A><Y><G><A><Q><S><V><S><V><T><T><Q><G><A><F><T><G><D><V><S><A><D><M><I><A><H><L><G><C><S><Y><V><I><V><G><H><S><E><R...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
B3DRW0
O43033
YGU4_SCHPO
Uncharacterized methyltransferase C3B9.04, mitochondrial
Schizosaccharomyces
<M><G><I><L><K><K><T><I><F><I><G><G><I><Y><G><L><G><V><Y><I><G><A><V><A><W><R><L><R><K><D><V><L><N><Y><E><S><R><Q><K><S><D><L><L><I><P><N><S><N><S><I><S><I><Y><N><Q><I><A><D><K><Y><S><R><K><I><T><R><E><E><I><F><S><G><I><Y><F><L><R><Y><F><L><L><R><N><A><K><G><D><V><L><E><V><G><S><G><P><G><T><N><F><P><F><Y><K><W><K><K><I...
Probable methyltransferase.<BOP>
O43033
Q73S79
Y4197_MYCPA
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4197c
Mycobacterium avium complex (MAC)
<M><T><R><T><D><Q><D><S><W><D><L><A><S><S><V><G><A><T><A><T><M><V><A><A><A><R><A><L><A><S><T><G><E><R><P><I><I><N><D><P><F><A><A><P><L><V><R><A><V><G><L><D><F><F><R><R><L><V><D><G><E><V><A><P><A><D><P><Q><R><G><E><R><D><L><Q><L><E><T><D><S><I><A><V><R><T><R><F><F><D><D><F><F><T><G><A><A><R><D><G><I><R><Q><S><V><I><L><A...
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP>
Q73S79
Q7N9T4
YIHI_PHOLL
Der GTPase-activating protein YihI
Photorhabdus
<M><N><P><L><K><K><K><A><P><A><K><V><S><A><S><K><Q><K><R><K><N><R><E><E><L><N><A><E><G><R><A><R><K><R><E><K><K><H><R><G><N><P><P><G><N><R><N><Q><E><Q><S><G><D><K><H><P><S><G><K><Q><Q><R><D><P><R><L><G><S><K><V><P><V><P><L><I><V><G><E><Q><P><T><K><P><V><V><A><N><K><V><E><T><K><P><R><L><S><P><Q><E><E><L><A><M><L><E><N><D...
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.<BOP>
Q7N9T4
Q9PJS0
YIDD_CHLMU
Putative membrane protein insertion efficiency factor
Chlamydia
<M><K><T><S><W><I><K><I><F><F><Q><G><M><I><H><L><Y><R><W><T><I><S><P><L><L><G><S><P><C><R><F><F><P><S><C><S><E><Y><A><L><V><A><L><K><K><H><P><L><K><R><S><L><F><L><I><A><N><R><L><L><K><C><G><P><W><H><I><G><G><I><D><L><V><P><G><T><S><I><E><E><Y><L><E><S><P><D><D><K><N><V><P><P><D><Q><E><T><V>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q9PJS0
Q2NL26
TKTL1_BOVIN
Transketolase 2
Bos
<M><A><D><A><E><A><S><A><T><M><A><D><E><A><K><P><D><S><K><T><L><Q><I><L><R><D><M><A><N><R><L><R><I><H><S><I><R><A><T><C><A><S><S><S><G><H><P><I><S><C><S><S><A><A><E><I><M><S><V><L><F><F><H><V><M><R><Y><K><Q><A><D><P><K><N><P><D><N><D><R><F><I><L><S><K><R><L><S><F><V><D><V><A><T><G><W><L><G><Q><G><L><G><A><A><C><G><M><A...
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.<BOP>
Q2NL26
B1VSW9
UREG2_STRGG
Urease accessory protein UreG 2
Streptomyces
<M><R><H><G><H><P><P><T><D><I><H><H><G><I><N><Q><G><E><P><M><D><D><N><V><L><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><I><E><A><L><V><P><V><L><I><E><R><G><H><R><P><A><V><I><T><N><D><I><Y><T><Q><E><D><A><Q><H><V><R><R><T><L><A><G><V><L><E><P><E><R><V><V><G><V><E><T><G><A><C><P><H><T><A><V><R><D><D><P><T><M><N><L><A><A...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B1VSW9
Q495A1
TIGIT_HUMAN
V-set and transmembrane domain-containing protein 3
Homo
<M><R><W><C><L><L><L><I><W><A><Q><G><L><R><Q><A><P><L><A><S><G><M><M><T><G><T><I><E><T><T><G><N><I><S><A><E><K><G><G><S><I><I><L><Q><C><H><L><S><S><T><T><A><Q><V><T><Q><V><N><W><E><Q><Q><D><Q><L><L><A><I><C><N><A><D><L><G><W><H><I><S><P><S><F><K><D><R><V><A><P><G><P><G><L><G><L><T><L><Q><S><L><T><V><N><D><T><G><E><Y><F...
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.<BOP>
Q495A1
B5ZAX5
Y158_UREU1
UPF0122 protein UUR10_0158
Ureaplasma
<M><L><N><K><N><K><R><W><Y><L><I><A><L><Y><D><I><Y><Q><G><L><L><T><T><K><Q><C><E><Y><F><N><L><H><Y><F><K><D><L><S><F><S><E><I><A><E><L><K><E><V><S><K><S><A><I><S><D><C><L><N><K><V><C><D><Q><L><L><K><Y><E><Q><A><L><L><I><Y><E><K><N><K><K><R><N><D><L><Y><T><L><I><N><D><S><E><L><V><K><K><L><K><D><I>
Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.<BOP>
B5ZAX5
Q6FQJ1
VPS27_CANGA
Vacuolar protein sorting-associated protein 27
Nakaseomyces/Candida clade
<M><A><T><T><S><S><E><E><F><S><E><V><I><E><R><A><T><S><E><S><I><P><N><G><E><L><N><L><P><V><A><L><E><I><S><D><I><L><R><S><R><R><I><A><P><K><D><G><M><R><C><L><K><K><R><I><T><N><T><T><N><N><P><N><T><Q><L><S><S><W><K><L><V><E><I><C><I><K><N><G><G><I><P><F><L><R><E><I><C><S><R><E><F><M><D><T><M><E><H><T><I><L><K><Y><D><D><S...
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP>
Q6FQJ1
Q55GQ6
UPP_DICDI
UMP pyrophosphorylase
Dictyostelium
<M><S><Y><P><E><N><V><V><V><L><K><S><N><H><Q><L><K><G><L><F><T><I><I><R><N><R><E><T><K><R><E><D><F><I><F><Y><S><D><R><I><I><R><L><L><I><E><E><G><L><Y><C><L><P><F><H><E><T><T><I><T><T><P><T><G><C><E><Y><Q><G><V><T><F><A><S><K><I><C><G><V><S><I><V><R><A><G><E><S><M><E><A><G><L><R><A><V><C><K><H><I><K><I><G><K><I><L><I><Q...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
Q55GQ6
P84035
VM3BA_BOTAS
Snake venom metalloproteinase basparin-A
Bothrops
<S><H><D><N><A><Q><L><L><T><A><I><K><A><Y><I><A><T><M><C><D><P><K><M><A><V><I><M><A><H><E><I><G><H><G><G><Y><Y><G><Y><C><R><K><I><P><C><A><P><E><D><V><K><D><D><D><I><G><M><V><L><P><G><T><K>
Snake venom zinc metalloproteinase that catalyzes the conversion of prothrombin (F2) to alpha-thrombin through formation of a thrombin intermediate, without requiring additional cofactors. Also inhibits collagen-dependent platelet aggregation in vitro, an effect that does not depend on proteolytic activity. In vivo, at...
P84035
A3QD46
TOLB_SHELP
Tol-Pal system protein TolB
Shewanella
<M><K><N><L><G><R><W><L><I><L><G><L><A><F><L><T><I><P><A><K><A><A><L><D><I><V><I><T><E><G><V><D><A><A><R><P><I><A><V><V><P><F><V><W><Q><G><S><T><P><M><P><Q><Q><I><S><D><V><V><M><S><D><L><T><R><S><G><T><F><K><P><M><D><E><L><G><L><P><Q><R><N><L><G><S><L><A><Q><M><D><L><K><A><W><S><N><V><A><A><E><A><V><V><M><G><T><V><K><P...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
A3QD46
B4RY55
UBID_ALTMD
Polyprenyl p-hydroxybenzoate decarboxylase
Alteromonas
<M><K><Y><K><D><L><R><D><F><I><R><Q><L><E><A><K><G><E><L><V><R><I><S><Q><P><I><D><T><D><L><E><M><T><E><I><A><D><R><T><L><R><A><G><G><P><A><L><L><F><E><N><P><K><N><H><D><M><P><V><L><A><N><L><F><G><T><P><E><R><V><A><M><G><M><G><Q><E><S><V><E><A><L><R><E><V><G><K><L><L><A><Y><L><K><E><P><E><P><P><K><G><L><K><D><L><W><E><K...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
B4RY55
Q7CRQ0
URODH_AGRFC
Hexuronate dehydrogenase
Agrobacterium tumefaciens complex
<M><K><R><L><L><V><T><G><A><A><G><Q><L><G><R><V><M><R><E><R><L><A><P><M><A><E><I><L><R><L><A><D><L><S><P><L><D><P><A><G><P><N><E><E><C><V><Q><C><D><L><A><D><A><N><A><V><N><A><M><V><A><G><C><D><G><I><V><H><L><G><G><I><S><V><E><K><P><F><E><Q><I><L><Q><G><N><I><I><G><L><Y><N><L><Y><E><A><A><R><A><H><G><Q><P><R><I><V><F><A...
Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5-lactone; in solution, this reaction product rearranges to...
Q7CRQ0
Q6PVW7
ZPBP2_CHICK
Zona pellucida-binding protein 2
Gallus
<M><A><G><G><G><G><R><P><C><S><P><Q><R><A><L><L><G><M><V><A><I><M><A><V><V><A><E><A><R><W><G><A><P><G><R><A><R><A><A><P><E><E><D><Q><I><S><V><G><F><F><R><K><N><V><I><Y><G><N><V><R><R><A><E><N><V><Y><V><K><M><F><T><N><S><P><S><L><V><C><M><D><L><S><L><S><Q><E><E><I><I><D><P><K><Y><S><W><T><G><P><D><G><R><N><L><E><G><R><G...
May be implicated in the gamete interaction during fertilization.<BOP>
Q6PVW7
P04185
UROK_PIG
Urokinase-type plasminogen activator chain B
Sus
<M><R><V><L><R><A><C><L><S><L><C><V><L><V><V><S><D><S><K><G><S><H><E><L><H><Q><E><S><G><A><S><N><C><G><C><L><N><G><G><K><C><V><S><Y><K><Y><F><S><N><I><Q><R><C><S><C><P><K><K><F><Q><G><E><H><C><E><I><D><T><S><Q><T><C><F><E><G><N><G><H><S><Y><R><G><K><A><N><T><N><T><G><G><R><P><C><L><P><W><N><S><A><T><V><L><L><N><T><Y><H...
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.<BOP>
P04185
Q6G5P5
TILS_BARHE
tRNA(Ile)-lysidine synthetase
Bartonella
<M><C><V><R><L><A><G><N><L><F><K><T><S><D><F><I><Q><C><Q><K><L><I><L><A><V><S><G><G><S><D><S><L><A><L><L><F><L><V><K><D><H><L><K><T><L><S><V><P><P><E><I><I><V><V><T><V><D><H><Q><L><R><Q><E><S><A><R><E><A><S><I><V><A><E><I><C><R><A><H><H><I><Q><H><R><I><V><R><W><E><G><K><K><P><K><T><H><I><A><S><S><A><R><V><A><R><Y><D><L...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
Q6G5P5
Q8T3S6
TXAA2_ARAVE
Toxin 2
Araneus
<M><A><L><A><L><L><G><L><T><I><K><P><E><H><V><P><E><G><T><G><K><A><V><A><D><V><E><A><L><A><C><D><P><A><Q><C><M><R><S><C><P><F><N><P><F><L><N><Q><Y><G><G><I><C><K><N><G><Q><C><V><C><V><K><P><S>
Putative insecticidal toxin.<BOP>
Q8T3S6
Q820E4
TRMD_CHLCV
tRNA [GM37] methyltransferase
Chlamydia
<M><E><I><E><I><L><S><L><F><P><D><Y><F><D><S><P><L><R><S><S><I><L><G><K><A><I><K><N><G><L><L><K><I><Q><S><R><D><I><R><D><F><G><L><G><K><W><K><Q><V><D><D><A><P><F><N><N><D><G><M><L><L><M><A><E><P><V><V><Q><A><I><R><H><I><K><R><S><D><S><R><V><I><H><L><S><P><Q><G><K><P><L><T><A><Q><K><S><R><E><L><A><K><C><S><H><L><I><F><L...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q820E4
P24055
TF_RABIT
Coagulation factor III
Oryctolagus
<M><A><P><P><T><R><L><Q><V><P><R><P><G><T><A><V><P><Y><T><V><L><L><G><W><L><L><A><Q><V><A><R><A><A><D><T><T><G><R><A><Y><N><L><T><W><K><S><T><N><F><K><T><I><L><E><W><E><P><K><S><I><D><H><V><Y><T><V><Q><I><S><T><R><L><E><N><W><K><S><K><C><F><L><T><A><E><T><E><C><D><L><T><D><E><V><V><K><D><V><G><Q><T><Y><M><A><R><V><L><S...
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<BOP>
P24055
Q7VFX7
UVRB_HELHP
Excinuclease ABC subunit B
Helicobacter
<M><G><K><F><I><L><D><S><Q><F><A><P><A><G><D><Q><P><Q><A><I><Q><K><I><T><Q><F><I><H><N><G><A><Q><Y><S><T><L><V><G><V><T><G><S><G><K><T><Y><T><M><A><N><I><I><A><N><L><N><I><P><T><L><I><M><T><H><N><K><T><L><A><A><Q><L><Y><S><E><F><R><G><F><F><P><K><N><H><V><E><Y><F><I><S><H><F><D><Y><Y><Q><P><E><A><Y><I><P><R><R><D><L><F...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
Q7VFX7
A5D3C3
YQGF_PELTS
Putative pre-16S rRNA nuclease
Pelotomaculum
<M><R><I><M><G><L><D><L><G><D><K><K><I><G><V><A><L><S><D><P><M><G><W><T><A><Q><G><L><D><V><I><A><V><K><G><P><P><E><A><S><V><E><R><I><S><E><L><V><R><Q><Y><G><V><G><K><I><V><V><G><L><P><R><N><M><N><G><S><F><G><P><R><A><E><R><A><R><A><F><A><G><C><L><A><G><A><L><N><L><P><V><E><L><W><D><E><R><M><T><T><L><E><A><E><K><L><L><I...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
A5D3C3
B7LWL0
TRUD_ESCF3
tRNA-uridine isomerase D
Escherichia
<M><I><E><F><D><N><L><T><Y><L><H><G><K><P><Q><G><T><G><L><L><K><A><N><P><E><D><F><V><V><V><E><D><L><G><F><E><P><D><G><E><G><E><H><I><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><F><C><A><R><V><P><G><K><E><M><P><D><L><S><A><F><Q><L><E...
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP>
B7LWL0
Q9ZJG8
YIDC_HELPJ
Membrane protein YidC
Helicobacter
<M><D><K><N><N><N><N><N><L><R><L><I><L><A><I><A><L><S><F><L><F><I><A><L><Y><S><Y><F><F><Q><E><P><N><K><T><T><T><E><T><T><K><Q><E><T><T><N><N><H><T><A><T><S><P><T><A><S><N><T><I><T><Q><D><F><S><V><T><Q><T><I><P><Q><E><S><L><L><S><T><I><S><F><E><H><A><K><I><E><I><D><S><L><G><R><I><K><Q><V><Y><L><K><D><K><K><Y><L><T><P><K...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
Q9ZJG8
P77315
YPHD_ECOLI
Probable ABC transporter permease protein YphD
Escherichia
<M><S><A><S><S><L><P><L><P><Q><G><K><S><V><S><L><K><Q><F><V><S><R><H><I><N><E><I><G><L><L><V><V><I><A><I><L><Y><L><V><F><S><L><N><A><P><G><F><I><S><L><N><N><Q><M><N><V><L><R><D><A><A><T><I><G><I><A><A><W><A><M><T><L><I><I><I><S><G><E><I><D><V><S><V><G><P><M><V><A><F><V><S><V><C><L><A><F><L><L><Q><F><E><V><P><L><A><V><A...
Probably part of the binding-protein-dependent transport system YphDEF. Probably responsible for the translocation of the substrate across the membrane.<BOP>
P77315
Q7TTX7
TGT_PARMW
tRNA-guanine transglycosylase
Parasynechococcus marenigrum
<M><F><G><F><E><I><S><A><H><C><A><N><T><A><A><R><C><G><C><F><H><T><P><H><G><P><V><H><T><P><R><F><M><P><V><G><T><L><A><T><V><K><G><I><S><T><D><Q><L><A><R><T><G><A><Q><M><V><L><S><N><T><Y><H><L><H><L><Q><P><G><E><E><I><V><A><A><A><G><G><L><H><G><F><M><G><W><D><G><P><M><L><T><D><S><G><G><F><Q><V><F><S><L><G><D><L><N><K><I...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
Q7TTX7
A7Z0S0
TRUA_BACVZ
tRNA-uridine isomerase I
Bacillus amyloliquefaciens group
<M><R><V><K><C><T><I><A><Y><D><G><H><L><F><N><G><Y><Q><V><Q><P><G><K><R><T><V><Q><S><E><L><E><K><A><L><A><V><I><H><K><T><D><G><R><V><P><V><Y><S><S><G><R><T><D><S><D><V><H><A><A><G><Q><V><I><H><F><D><T><P><L><S><I><P><G><E><K><W><P><F><A><L><N><A><L><L><P><D><D><I><A><V><K><T><A><E><I><A><D><D><G><F><H><A><R><F><S><A><V...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
A7Z0S0
Q9A6H0
TYSY_CAUVC
Thymidylate synthase
Caulobacter
<M><S><T><A><V><L><D><A><P><K><A><A><T><D><H><P><E><R><Q><Y><L><T><L><L><A><D><I><L><E><N><G><V><Q><R><G><D><R><T><G><T><G><T><L><G><V><F><G><R><Q><I><R><F><D><L><A><K><G><F><P><V><L><T><T><K><K><L><H><L><R><S><I><I><I><E><L><L><W><F><L><K><G><D><T><N><I><A><Y><L><K><D><N><G><V><R><I><W><D><E><W><A><D><E><N><G><D><L><G...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
Q9A6H0
P23669
THRC_CORGL
Threonine synthase
Corynebacterium
<M><D><Y><I><S><T><R><D><A><S><R><T><P><A><R><F><S><D><I><L><L><G><G><L><A><P><D><G><G><L><Y><L><P><A><T><Y><P><Q><L><D><D><A><Q><L><S><K><W><R><E><V><L><A><N><E><G><Y><A><A><L><A><A><E><V><I><S><L><F><V><D><D><I><P><V><E><D><I><K><A><I><T><A><R><A><Y><T><Y><P><K><F><N><S><E><D><I><V><P><V><T><E><L><E><D><N><I><Y><L><G...
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP>
P23669
P38987
TEM1_YEAST
Protein TEM1
Saccharomyces
<M><A><T><P><S><T><G><A><N><N><S><I><P><A><V><R><N><Q><V><E><V><Q><V><G><L><V><G><D><A><Q><V><G><K><T><S><L><M><V><K><Y><V><Q><N><I><Y><D><K><E><Y><T><Q><T><L><G><V><N><F><L><K><R><K><V><S><I><R><S><T><D><I><I><F><S><I><M><D><L><G><G><Q><R><E><F><I><N><M><L><P><I><A><T><V><G><S><S><V><I><I><F><L><F><D><L><T><R><P><E><T...
GTP-binding protein involved in termination of M phase. May play a role in triggering the degradation of G2 cyclin to inactivate M-phase promoting factor at the termination of mitosis. Acts upstream of CDC15 kinase and may be required to activate the CDC15 protein kinase pathway.<BOP>
P38987
Q7WY78
TAGT_BACSU
Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagT
Bacillus
<M><E><E><R><S><Q><R><R><K><K><K><R><K><L><K><K><W><V><K><V><V><A><G><L><M><A><F><L><V><I><A><A><G><S><V><G><A><Y><A><F><V><K><L><N><N><A><S><K><E><A><H><V><S><L><A><R><G><E><Q><S><V><K><R><I><K><E><F><D><P><G><K><D><S><F><S><V><L><L><L><G><I><D><A><R><E><K><N><G><E><T><V><D><Q><A><R><S><D><A><N><V><L><V><T><F><N><R><K...
May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).<BOP>
Q7WY78
A7LAC6
VSP1_TRIAB
Snake venom serine protease
Trimeresurus
<M><V><L><I><T><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><S><S><E><L><V><I><G><G><D><E><C><N><I><N><E><H><R><F><L><V><A><L><Y><D><V><W><S><G><D><F><L><C><G><G><T><L><I><N><K><E><Y><V><L><T><A><A><H><C><E><T><R><N><M><Y><I><Y><L><G><M><H><N><K><N><V><Q><F><D><D><E><Q><R><R><Y><P><K><K><K><Y><F><F><R><C><S><N><N><F><T...
Thrombin-like snake venom serine protease.<BOP>
A7LAC6
Q8ZK90
ULAA_SALTY
Ascorbate-specific permease IIC component UlaA
Salmonella
<M><E><I><L><Y><N><I><F><T><I><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><E><R><M><G><D><A><Y><S><W><V><G><Y><A...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP...
Q8ZK90
O14273
YET4_SCHPO
Meiotically up-regulated protein C8C9.04
Schizosaccharomyces
<M><T><T><N><P><D><I><V><K><Q><T><K><N><E><I><H><Q><V><T><S><R><V><Q><E><K><L><D><S><K><S><T><N><A><V><E><Q><N><N><N><S><S><Q><A><S><V><T><K><D><N><K><K><K><A><A><K><R><A><K><K><K><A><A><K><K><K><K><Q><S><A><A><A><S><A><S><S><T><P><V><E><E><A><Q><H><A><Q><E><E><Q><Q><E><Q><T><I><L><Q><E><P><G><F><T><Q><T><I><V><E><K><D...
Has a role in meiosis and sporulation.<BOP>
O14273
Q5FWF6
ZN789_HUMAN
Zinc finger protein 789
Homo
<M><F><P><P><A><R><G><K><E><L><L><S><F><E><D><V><A><M><Y><F><T><R><E><E><W><G><H><L><N><W><G><Q><K><D><L><Y><R><D><V><M><L><E><N><Y><R><N><M><V><L><L><G><F><Q><F><P><K><P><E><M><I><C><Q><L><E><N><W><D><E><Q><W><I><L><D><L><P><R><T><G><N><R><K><A><S><G><S><A><C><P><G><S><E><A><R><H><K><M><K><K><L><T><P><K><Q><K><F><S><E...
May be involved in transcriptional regulation.<BOP>
Q5FWF6
A1K8Q1
UBIG_AZOSB
3-demethylubiquinone 3-O-methyltransferase
Azoarcus
<M><N><T><N><A><D><P><A><E><V><Q><K><F><S><D><L><A><H><R><W><W><D><P><A><S><E><F><K><P><L><H><E><I><N><P><L><R><L><D><W><I><D><G><H><C><G><L><A><G><K><K><V><L><D><V><G><C><G><G><G><L><L><S><E><G><M><A><Q><R><G><A><E><V><S><G><I><D><L><S><E><K><A><L><G><V><A><R><L><H><L><Y><E><S><G><L><Q><V><D><Y><Q><L><T><S><A><E><A><H...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
A1K8Q1
Q0TEV3
TRMJ_ECOL5
tRNA Cm32/Um32 methyltransferase
Escherichia
<M><L><Q><N><I><R><I><V><L><V><E><T><S><H><T><G><N><M><G><S><V><A><R><A><M><K><T><M><G><L><T><N><L><W><L><V><N><P><L><V><K><P><D><S><Q><A><I><A><L><A><A><G><A><S><D><V><I><G><N><A><H><I><V><D><T><L><D><E><A><L><A><G><C><S><L><V><V><G><T><S><A><R><S><R><T><L><P><W><P><I><L><D><P><R><E><C><G><L><K><S><V><A><E><A><A><N><T...
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.<BOP>
Q0TEV3
P07911
UROM_HUMAN
Uromodulin, secreted form
Homo
<M><G><Q><P><S><L><T><W><M><L><M><V><V><V><A><S><W><F><I><T><T><A><A><T><D><T><S><E><A><R><W><C><S><E><C><H><S><N><A><T><C><T><E><D><E><A><V><T><T><C><T><C><Q><E><G><F><T><G><D><G><L><T><C><V><D><L><D><E><C><A><I><P><G><A><H><N><C><S><A><N><S><S><C><V><N><T><P><G><S><F><S><C><V><C><P><E><G><F><R><L><S><P><G><L><G><C><T...
In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.<BOP>
P07911
Q81GG4
TRPA_BACCR
Tryptophan synthase alpha chain
Bacillus cereus group
<M><G><V><E><K><I><K><A><A><F><E><N><G><K><K><A><F><I><P><Y><V><M><G><G><D><G><G><L><E><K><L><K><E><R><I><R><F><L><D><E><A><G><A><S><I><V><E><I><G><I><P><F><S><D><P><V><A><D><G><P><T><I><Q><R><A><G><K><R><A><L><D><S><G><V><T><L><K><G><I><F><Q><A><L><A><E><V><R><K><E><V><Q><M><P><F><V><L><M><T><Y><L><N><P><V><L><A><F><G...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q81GG4
Q31910
YCF4_BRAOL
Photosystem I assembly protein Ycf4
Brassica
<M><T><W><R><S><E><H><I><W><I><D><L><I><S><G><S><R><K><K><S><N><F><C><W><A><F><L><L><F><L><G><S><L><G><F><V><L><V><G><T><S><S><Y><L><G><R><N><L><I><S><S><F><P><P><Q><Q><I><T><F><F><P><Q><G><L><V><M><S><F><Y><G><I><A><G><L><F><I><S><C><Y><L><W><C><T><I><L><W><N><V><G><S><G><Y><D><L><F><D><R><K><E><G><I><V><R><I><F><R><W...
Seems to be required for the assembly of the photosystem I complex.<BOP>
Q31910
Q5PQR8
TPRKB_RAT
TP53RK-binding protein
Rattus
<M><Q><L><T><Q><Q><L><D><L><F><P><E><C><K><V><T><L><L><L><F><K><D><V><K><N><A><G><D><L><R><K><K><A><M><E><G><S><I><D><G><S><L><I><N><A><N><V><I><V><D><P><F><Q><I><L><V><A><A><N><K><A><V><H><L><H><K><L><G><K><M><K><T><R><T><L><S><T><E><I><I><F><N><L><S><P><N><N><N><I><S><E><A><L><K><K><F><G><I><S><E><S><N><T><S><V><L><I...
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of...
Q5PQR8
A6LT26
TIG_CLOB8
PPIase
Clostridium
<M><K><A><K><V><E><K><I><E><T><N><V><I><K><L><E><I><R><V><E><A><E><K><F><D><A><A><L><T><K><A><Y><N><K><N><K><G><R><Y><N><I><P><G><F><R><K><G><K><V><P><M><A><M><V><K><K><F><Y><G><V><E><V><F><Y><D><D><A><V><N><F><A><I><D><E><S><Y><P><E><A><L><N><A><E><N><I><K><P><V><D><Y><P><Q><V><D><I><V><E><L><G><E><G><K><E><L><V><Y><T...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A6LT26
Q12QH9
TRUB_SHEDO
tRNA-uridine isomerase
Shewanella
<M><A><R><R><S><K><G><R><Q><I><D><G><I><V><L><L><D><K><D><T><G><M><S><S><N><Y><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><V><R><T><D><T><S><D><S><D><G><E><V><V><Q><T><R><D><I><N><F><T><Q><A><Q><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q12QH9
Q811H0
ZBT42_MOUSE
Protein simiRP58
Mus
<M><E><F><P><E><H><G><V><R><L><L><G><R><L><R><Q><Q><R><E><L><G><F><L><C><D><C><T><V><L><V><G><D><A><R><F><P><A><H><R><A><V><L><A><A><C><S><V><Y><F><H><L><F><Y><R><D><Q><P><A><S><S><R><D><T><V><R><L><N><G><D><I><V><T><V><P><A><F><S><R><L><L><D><F><M><Y><E><G><R><L><D><L><H><N><L><P><V><E><D><V><L><A><A><A><S><Y><L><H><M...
Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes.<BOP>
Q811H0
Q2NIY3
TRUA_AYWBP
tRNA-uridine isomerase I
Candidatus Phytoplasma asteris
<M><Q><H><F><F><Y><K><L><I><L><S><Y><D><G><T><F><Y><C><G><Y><Q><K><Q><P><Q><K><K><T><V><Q><Q><T><F><E><K><A><L><K><K><M><T><H><Q><N><I><P><T><F><A><A><S><R><T><D><K><G><V><H><S><Q><G><Q><T><L><H><F><Q><T><T><F><S><L><K><P><K><H><F><Q><K><T><L><N><Y><L><L><P><P><D><I><R><V><R><Q><M><H><F><A><T><P><N><F><H><A><R><Y><S><A...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
Q2NIY3
Q8UVG0
VM3BE_BOTER
ery1
Bothrops
<M><I><Q><V><L><L><V><I><I><C><L><E><A><F><P><Y><Q><G><S><S><I><I><L><E><S><G><N><V><N><D><Y><E><V><V><Y><P><R><K><V><T><A><L><S><K><G><A><V><H><P><K><Y><E><D><A><M><Q><Y><E><F><K><V><N><G><E><P><V><V><L><H><L><E><K><N><K><G><L><F><S><E><D><Y><S><E><I><H><Y><S><P><D><G><R><E><I><T><T><Y><P><L><V><E><D><H><C><Y><Y><H><G...
Potent activator of prothrombin (F2). Does not elicit any hemorrhagic response. Barely inhibits collagen-induced platelet aggregation. Binds neither collagen, nor the jararhagin monoclonal antibody MAJar3. Hydrolyzes the Aalpha-chain of fibrin and fibrinogen, without affecting the Bbeta- and gamma-chains. Is capable of...
Q8UVG0
P69823
ULAB_ECO57
Ascorbate-specific phosphotransferase enzyme IIB component
Escherichia
<M><T><V><R><I><L><A><V><C><G><N><G><Q><G><S><S><M><I><M><K><M><K><V><D><Q><F><L><T><Q><S><N><I><D><H><T><V><N><S><C><A><V><G><E><Y><K><S><E><L><S><G><A><D><I><I><I><A><S><T><H><I><A><G><E><I><T><V><T><G><N><K><Y><V><V><G><V><R><N><M><L><S><P><A><D><F><G><P><K><L><L><E><V><I><K><E><H><F><P><Q><D><V><K>
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP...
P69823
Q1WTU0
YBEY_LIGS1
Endoribonuclease YbeY
Ligilactobacillus
<M><D><L><E><I><F><D><D><T><N><S><V><P><A><E><K><I><Q><L><V><K><D><V><L><E><F><S><G><K><Y><L><E><L><P><E><D><T><E><M><S><V><T><L><M><N><N><E><Q><I><H><E><I><N><L><K><Y><R><G><V><D><K><A><T><D><V><I><S><F><A><I><E><E><D><D><P><D><E><L><P><I><I><L><P><D><D><V><D><F><E><E><P><K><N><I><G><D><M><M><I><S><M><D><K><V><K><E><Q...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
Q1WTU0
P86392
VMPA1_TITSE
Metalloserrulase 1
Tityus
<M><I><S><Y><L><A><S><I><F><L><L><A><T><V><S><A><V><P><S><G><R><V><E><V><V><F><P><S><V><E><T><S><R><S><G><V><K><T><V><K><F><T><A><L><D><Q><D><V><E><L><K><L><R><S><A><G><E><I><L><G><K><R><F><A><I><Q><D><V><D><V><E><S><L><R><R><K><I><Y><R><D><S><V><N><G><A><A><L><L><I><D><E><D><G><P><L><T><I><E><G><I><V><N><S><K><L><R><I...
Acts as a metalloprotease. Penetrates intact tissue and specifically cleaves the vesicle-associated membrane protein 2 (VAMP2) (part of the SNARE complex) involved in pancreatic secretion, thus disrupting the normal vesicular traffic.<BOP>
P86392
Q47AM7
TATA_DECAR
Sec-independent protein translocase protein TatA
Dechloromonas
<M><G><S><F><S><I><W><H><W><L><I><V><L><V><I><V><M><L><I><F><G><T><K><K><L><R><N><V><G><Q><D><L><G><G><A><V><K><G><F><K><D><G><M><K><E><A><N><A><D><K><P><A><E><E><A><Q><P><T><Q><Q><V><G><G><H><T><I><D><V><E><V><K><E><K><T><K><S>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q47AM7
A6UW21
TRPD_META3
Anthranilate phosphoribosyltransferase
Methanococcus
<M><L><N><K><I><I><N><R><E><D><L><S><Y><E><E><S><Y><D><L><F><N><D><L><L><N><E><S><E><I><K><I><G><A><Y><L><S><A><L><Q><T><K><G><F><T><A><N><E><I><A><G><F><A><K><A><M><R><D><N><A><I><A><I><D><L><G><K><G><I><S><D><T><C><G><T><G><G><D><G><Y><S><T><I><N><I><S><T><A><V><S><I><I><L><S><C><F><T><K><V><A><K><H><G><N><V><S><I><T...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
A6UW21
Q4FNF0
YIDD_PELUB
Putative membrane protein insertion efficiency factor
Candidatus Pelagibacter
<M><N><I><I><S><N><I><L><I><G><L><I><K><F><Y><K><M><V><I><S><P><Y><L><T><P><S><C><R><Y><L><P><T><C><S><E><Y><T><I><E><C><L><R><T><Y><G><L><V><K><A><I><S><K><S><T><K><R><I><F><S><C><H><P><I><K><I><L><G><G><G><E><G><F><D><P><V><N><K><E><F><K><A><K><K>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q4FNF0
A6SY03
TPIS_JANMA
Triose-phosphate isomerase
Janthinobacterium
<M><R><R><K><L><V><A><G><N><W><K><M><N><G><S><L><A><A><N><T><L><L><L><T><E><I><K><S><G><L><G><N><A><T><S><D><V><A><V><C><V><P><S><P><Y><F><A><Q><C><Q><G><L><L><N><G><A><A><I><A><L><G><A><Q><D><V><S><S><H><E><A><G><A><Y><T><G><E><V><S><T><S><M><L><Q><E><F><D><C><R><Y><V><I><V><G><H><S><E><R><R><A><Y><F><A><E><T><N><E><L...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
A6SY03
Q5Z355
Y294_NOCFA
Nucleoid-associated protein NFA_2940
Nocardia
<M><Q><P><G><G><Q><F><D><M><Q><Q><L><L><A><Q><A><Q><Q><M><Q><E><A><V><M><Q><A><Q><A><E><I><A><A><T><E><V><E><G><Q><A><G><G><G><L><V><K><A><T><I><K><A><T><G><E><V><Q><A><L><T><I><D><P><K><V><V><D><P><E><D><V><E><G><L><Q><D><L><V><I><G><A><I><N><D><A><M><A><R><A><Q><Q><L><A><A><E><R><L><G><P><L><A><G><G><G><S><M><P><G><L...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
Q5Z355
Q8RX78
UBN1_ARATH
Ubiquitously expressed nuclear protein 1
Arabidopsis
<M><S><E><V><N><E><M><S><G><G><S><I><G><G><E><L><L><R><A><S><P><K><V><L><T><A><G><D><R><K><L><L><K><V><E><L><R><P><G><D><T><T><Y><V><S><W><K><K><L><M><R><D><A><G><K><V><N><G><L><S><A><S><V><P><D><P><P><P><N><A><N><P><N><L><E><F><R><I><A><P><G><H><P><V><E><I><E><T><N><E><Q><P><H><S><N><R><F><N><A><V><I><E><K><I><E><R><L...
May be required for replication-independent chromatin assembly.<BOP>
Q8RX78
B4SUI9
TREA_SALNS
Alpha,alpha-trehalose glucohydrolase
Salmonella
<M><I><P><P><E><I><R><R><S><V><L><L><Q><K><A><I><K><L><A><L><A><G><T><L><L><T><F><A><S><F><S><A><T><A><A><D><P><S><S><D><T><E><T><P><Q><P><P><D><I><L><L><G><P><L><F><N><D><V><Q><N><A><K><L><F><P><D><Q><K><T><F><A><D><A><I><P><N><S><D><P><L><M><I><L><A><D><Y><R><M><Q><R><N><Q><S><G><F><D><L><R><H><F><V><D><V><N><F><T><L...
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.<BOP>
B4SUI9
Q8T0W4
VKT2_PIMHY
Cysteine-rich venom protein 2
Pimpla
<M><N><A><K><I><V><A><L><L><I><V><V><G><F><V><G><M><F><N><V><A><T><A><A><D><P><L><C><S><L><E><P><A><V><G><L><C><K><A><S><I><P><R><F><A><S><V><G><G><K><C><Q><E><F><I><Y><G><G><C><G><G><N><A><N><N><F><Q><T><Q><A><E><C><E><A><K><C><G>
Serine protease inhibitor.<BOP>
Q8T0W4
Q7U330
TRUB_HELHP
tRNA-uridine isomerase
Helicobacter
<M><A><N><A><L><L><V><A><A><Y><K><P><P><F><L><S><S><N><A><C><L><S><R><L><K><K><H><F><G><M><S><K><A><G><Y><L><G><T><L><D><P><F><A><K><G><V><L><V><V><G><F><G><S><Y><T><R><L><F><P><H><L><Q><K><V><P><K><A><Y><R><A><T><L><W><L><G><A><K><S><A><S><L><D><I><E><H><I><E><S><I><E><I><I><P><E><Y><N><Q><S><D><I><E><K><I><L><F><S><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q7U330
Q7M715
TR117_MOUSE
Taste receptor type 2 member 117
Mus
<M><K><H><F><W><K><I><L><S><V><I><S><Q><S><T><L><S><V><I><L><I><V><E><L><V><I><G><I><I><G><N><G><F><M><V><L><V><H><C><M><D><W><V><K><K><K><K><M><S><L><V><N><Q><I><L><T><A><L><S><I><S><R><I><F><Q><L><C><L><L><F><I><S><L><V><I><N><F><S><Y><T><D><L><T><T><S><S><R><M><I><Q><V><M><Y><N><A><W><I><L><A><N><H><F><S><I><W><I><A...
Putative taste receptor which may play a role in the perception of bitterness.<BOP>
Q7M715
Q31HG2
TPIS_HYDCU
Triose-phosphate isomerase
Hydrogenovibrio
<M><R><Q><L><F><V><A><G><N><W><K><M><H><G><D><K><A><S><I><K><T><L><V><T><G><L><N><A><K><A><D><S><V><G><D><V><L><V><A><V><C><P><P><A><I><Y><L><D><Y><T><K><N><C><L><M><A><G><E><I><A><L><G><G><Q><N><M><A><I><E><P><V><Q><G><A><Y><T><G><E><T><S><A><S><M><L><K><D><V><G><C><Q><Y><V><I><L><G><H><S><E><R><R><A><I><Y><G><E><T><D...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q31HG2
C5XNN6
THI41_SORBI
Thiazole biosynthetic enzyme 1
Sorghum
<M><A><T><T><A><A><S><S><L><L><K><S><S><F><A><G><S><R><L><P><S><A><T><R><A><P><S><S><V><V><V><S><T><G><G><A><P><R><T><A><A><I><S><A><S><I><S><S><S><N><P><P><Y><D><L><T><S><F><K><F><S><P><I><K><E><S><I><V><S><R><E><M><T><R><R><Y><M><T><D><M><I><T><H><A><D><T><D><V><V><I><V><G><A><G><S><A><G><L><S><C><A><Y><E><L><S><K><D...
Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue o...
C5XNN6
P38141
THI2_YEAST
Thiamine biosynthesis regulatory protein
Saccharomyces
<M><V><N><S><K><R><Q><Q><R><S><K><K><V><A><S><S><S><K><V><P><P><T><K><G><R><T><F><T><G><C><W><A><C><R><F><K><K><R><R><C><D><E><N><R><P><I><C><S><L><C><A><K><H><G><D><N><C><S><Y><D><I><R><L><M><W><L><E><E><N><I><Y><K><V><R><K><H><S><L><I><S><S><L><Q><A><R><K><S><K><S><K><P><L><C><Q><K><I><S><K><S><R><F><K><Q><M><T><H><F...
Positive regulator of thiamine biosynthesis.<BOP>
P38141
C1AE25
THIM_GEMAT
4-methyl-5-beta-hydroxyethylthiazole kinase
Gemmatimonas
<M><D><A><P><S><S><A><S><G><P><T><Q><P><R><L><S><P><A><D><A><L><A><A><L><R><A><S><A><P><L><T><Q><C><I><T><N><Y><V><A><M><Q><I><A><A><N><T><L><L><A><A><G><A><A><P><A><M><I><H><T><V><E><E><S><G><A><F><A><G><L><A><R><A><V><T><I><N><I><G><T><L><S><P><A><W><V><D><G><M><K><A><A><I><D><G><A><T><A><V><G><T><P><W><V><L><D><P><V...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
C1AE25
Q9ABM9
TRMD_CAUVC
tRNA [GM37] methyltransferase
Caulobacter
<M><P><F><T><A><T><V><L><T><M><F><P><E><A><F><P><G><P><L><G><V><S><M><I><G><T><A><W><K><E><Q><D><L><W><R><L><E><T><L><D><I><R><A><F><S><K><D><K><R><G><F><L><D><D><T><P><A><G><G><G><A><G><A><V><L><K><A><D><V><I><A><S><A><L><D><S><L><E><R><D><G><R><P><L><L><Y><M><S><A><R><G><R><P><L><T><Q><A><R><V><R><E><W><S><K><A><P><G...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q9ABM9