accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q26474
LACH_SCHAM
Lachesin
Schistocerca
<M><D><L><R><L><Y><T><I><F><V><G><F><F><S><V><V><Y><A><Q><R><T><P><T><I><S><Y><I><S><Q><E><Q><I><K><D><I><G><G><T><V><E><L><E><C><S><V><Q><Y><A><Q><D><Y><P><V><L><W><M><K><V><D><R><N><R><Q><V><D><P><L><P><I><S><T><G><S><S><L><I><I><R><D><S><R><F><A><L><R><Y><D><T><A><S><S><T><Y><T><L><Q><I><K><D><I><Q><E><T><D><A><G><F...
May play a role in early neuronal differentiation and axon outgrowth.<BOP>
Q26474
B6JET4
RL4_AFIC5
50S ribosomal protein L4
Afipia
<M><E><L><N><V><T><T><L><E><G><K><A><A><G><S><V><N><L><S><D><T><I><F><G><L><E><P><R><T><D><I><I><Q><R><V><V><N><W><Q><L><A><K><R><Q><A><G><T><H><K><T><K><G><R><A><E><I><A><R><T><G><K><K><M><Y><K><Q><K><G><T><G><G><A><R><H><G><S><A><R><V><P><Q><F><R><G><G><G><R><A><F><G><P><V><V><R><S><H><A><Y><D><L><P><K><K><V><R><A><L...
Forms part of the polypeptide exit tunnel.<BOP>
B6JET4
C1GB49
LIS1_PARBD
nudF homolog
Paracoccidioides
<M><S><Q><L><L><T><A><R><Q><A><E><E><L><H><K><A><M><I><A><Y><L><L><S><A><N><L><P><K><S><A><A><A><L><R><E><E><L><A><D><S><V><Q><L><D><D><S><T><A><K><K><Y><E><G><L><L><E><K><K><W><T><S><V><V><R><L><Q><K><K><I><M><D><L><E><S><R><N><N><A><L><Q><S><E><L><D><S><A><T><P><T><S><L><A><R><R><N><Q><D><P><V><S><W><L><P><H><A><P><A...
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) trans...
C1GB49
Q606H8
RS6_METCA
30S ribosomal protein S6
Methylococcus
<M><R><H><Y><E><I><V><F><M><V><H><P><D><Q><S><G><Q><V><P><A><M><I><E><R><Y><R><S><I><I><E><G><A><A><G><R><I><H><R><L><E><D><W><G><R><R><Q><L><A><Y><P><I><A><K><L><H><K><A><H><Y><V><L><M><N><I><E><C><D><Q><A><T><L><E><E><L><E><S><G><F><R><F><N><D><A><V><L><R><S><L><T><I><R><R><D><E><A><V><T><E><P><S><A><L><A><R><S><G><S...
Binds together with S18 to 16S ribosomal RNA.<BOP>
Q606H8
C6HSY8
ARGJ_AJECH
Arginine biosynthesis bifunctional protein ArgJ beta chain
Histoplasma
<M><R><N><P><K><S><F><C><V><V><A><G><F><V><R><L><P><K><S><S><L><G><Q><V><R><Y><Y><S><I><P><N><D><V><S><I><P><A><S><K><G><K><F><I><P><G><S><G><T><Y><P><K><G><F><L><V><A><G><A><H><A><G><V><K><E><S><N><T><Q><F><P><D><V><A><L><I><C><S><E><T><P><C><S><A><A><A><V><F><T><T><N><K><F><Q><A><A><P><V><Q><V><S><K><Q><V><L><E><K><R...
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.<BOP>
C6HSY8
Q5P720
TGT_AROAE
tRNA-guanine transglycosylase
Aromatoleum
<M><Q><F><E><L><L><A><Q><H><G><A><A><R><R><G><R><L><T><L><A><H><G><T><V><D><T><P><A><F><M><P><V><G><T><Y><G><T><V><K><A><M><T><P><A><A><L><A><D><T><G><A><Q><I><C><L><G><N><T><F><H><L><W><L><R><P><G><L><D><V><V><A><A><H><G><G><L><H><R><F><M><N><W><D><R><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><G><A><L><R><K><I><S><E><E...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
Q5P720
D9U2A6
KA291_LYCMC
Toxin LmKTx2
Lychas
<M><K><S><V><C><G><V><L><I><I><L><V><V><L><T><T><M><L><S><I><S><T><F><S><T><V><G><A><E><G><D><C><P><I><S><E><A><I><K><C><V><E><K><C><K><E><K><V><E><V><C><E><P><G><V><C><K><C><S><G>
Weakly inhibits the Kv1.3/KCNA3 channel (1 uM of the toxin inhibits currents by 13.2%) and Kv7.1/KCNQ1 channel (10 uM of the toxin inhibits currents by 27.7%).<BOP>
D9U2A6
Q1BS32
HIS3_BURCA
Phosphoribosyl-AMP cyclohydrolase
Burkholderia cepacia complex
<M><N><T><E><T><K><S><L><P><A><W><L><D><K><V><R><W><D><D><N><G><L><V><P><V><I><A><Q><E><A><S><T><N><D><V><L><M><F><A><W><M><N><R><E><A><L><A><K><T><I><E><T><Q><R><A><V><Y><Y><S><R><S><R><K><R><L><W><F><K><G><E><E><S><G><H><V><Q><H><V><H><E><V><R><L><D><C><D><E><D><V><V><L><L><K><V><E><Q><V><S><G><I><A><C><H><T><G><R><H...
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.<BOP>
Q1BS32
Q8TIQ4
CRCB2_METAC
Putative fluoride ion transporter CrcB 2
Methanosarcina
<M><P><S><Q><D><K><E><I><D><K><I><F><L><I><G><A><G><G><F><L><G><A><V><C><R><F><L><L><C><E><L><V><E><G><Q><L><G><I><L><S><V><N><V><I><G><S><F><M><L><G><M><I><M><Y><D><T><E><Y><L><G><F><I><G><P><K><G><K><I><A><F><G><T><G><F><M><G><A><F><T><T><F><S><T><F><A><V><Q><S><F><S><L><P><F><I><P><A><L><G><N><I><S><A><N><I><F><L><T...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
Q8TIQ4
B2ITP0
RL18_NOSP7
50S ribosomal protein L18
Nostoc
<M><K><L><T><R><R><E><S><K><N><R><R><H><R><R><V><R><G><K><V><V><G><S><P><E><R><P><R><L><A><V><F><R><S><N><E><H><I><Y><A><Q><V><I><D><D><S><Q><H><Q><T><I><V><A><A><S><T><L><E><P><E><L><K><S><S><L><A><S><G><A><N><R><D><A><S><V><Q><V><G><K><L><I><A><V><R><S><L><E><K><G><I><T><K><V><V><F><D><R><G><G><N><L><Y><H><G><R><V><K...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
B2ITP0
A5WEG6
CYSG_PSYWF
Sirohydrochlorin ferrochelatase
Psychrobacter
<M><N><T><F><P><L><F><F><K><L><T><N><Q><P><V><L><I><V><G><G><G><E><V><A><Q><R><K><A><D><L><L><S><R><A><G><A><C><I><T><I><L><A><P><Q><I><S><Q><E><I><H><Q><L><L><S><D><E><R><H><T><L><I><T><A><H><Y><D><K><K><Y><I><D><G><K><R><I><V><I><A><G><T><D><D><E><A><L><N><H><Q><V><H><A><D><C><K><A><L><N><I><P><V><N><V><V><D><T><P><P...
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie...
A5WEG6
Q57HU2
ILVC_SALCH
Ketol-acid reductoisomerase type II
Salmonella
<M><A><N><Y><F><N><T><L><N><L><R><Q><Q><L><A><Q><L><G><K><C><R><F><M><G><R><D><E><F><A><D><G><A><S><Y><L><Q><G><K><K><V><V><I><V><G><C><G><A><Q><G><L><N><Q><G><L><N><M><R><D><S><G><L><D><I><S><Y><A><L><R><K><E><A><I><A><E><K><R><A><S><W><R><K><A><T><E><N><G><F><K><V><G><T><Y><E><E><L><I><P><Q><A><D><L><V><V><N><L><T><P...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
Q57HU2
J7FIP8
IDTP_CLAPA
Indole-diterpene biosynthesis cluster protein P
Claviceps
<M><F><L><L><H><I><L><A><I><G><A><C><L><L><W><Y><F><V><R><S><D><K><R><K><Q><G><S><N><I><P><T><I><R><R><W><P><A><L><F><P><E><F><L><D><R><L><S><Y><N><S><C><A><A><R><L><V><E><N><G><Y><R><E><H><K><D><R><P><F><R><L><L><K><M><D><M><D><L><V><V><I><P><L><K><Y><A><Q><E><M><R><A><L><T><S><D><E><L><D><P><L><T><A><V><F><D><D><N><V...
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals . The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of it...
J7FIP8
Q46M05
NDHK_PROMT
NDH-1 subunit K
Prochlorococcus
<M><E><L><N><P><L><K><K><S><P><S><S><E><A><V><R><N><L><R><E><A><S><C><G><P><V><G><T><P><T><V><T><N><D><L><S><E><N><I><I><L><T><S><L><E><D><L><H><N><W><A><R><L><S><S><L><W><P><L><L><Y><G><T><A><C><C><F><I><E><F><A><A><L><I><G><S><R><F><D><F><D><R><F><G><L><V><P><R><S><S><P><R><Q><A><D><L><L><I><V><A><G><T><V><T><M><K><M...
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus co...
Q46M05
B1JJK2
THIG_YERPY
Thiazole synthase
Yersinia
<M><L><K><I><A><D><T><T><F><T><S><R><L><F><T><G><T><G><K><F><S><S><P><E><L><M><L><E><A><L><R><A><S><G><S><Q><L><I><T><M><A><M><K><R><V><D><L><Q><S><G><N><D><A><I><L><A><P><L><R><Q><L><G><V><R><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><R><L><A><R><E><A><L><N><T><H><W><V><K><L><E><I><H><P><D><V><R><Y><L><L><P...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
B1JJK2
Q8HXY2
MCAT_MACFA
Solute carrier family 25 member 20
Macaca
<M><A><D><Q><P><K><P><I><S><P><L><K><N><L><L><A><G><G><F><G><G><V><C><L><V><F><V><G><H><P><L><D><T><V><K><V><R><L><Q><T><Q><P><P><S><L><P><G><Q><P><P><M><Y><S><G><T><F><D><C><F><R><K><T><L><F><R><E><G><I><R><G><L><Y><R><G><M><A><A><P><I><I><G><V><T><P><M><F><A><V><C><F><F><G><F><G><L><G><K><K><L><Q><Q><K><H><P><E><D><V...
Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism...
Q8HXY2
Q03497
STE20_YEAST
Serine/threonine-protein kinase STE20
Saccharomyces
<M><S><N><D><P><S><A><V><S><E><L><P><D><K><D><S><L><D><N><G><I><S><N><D><N><E><R><A><M><G><G><N><G><D><G><G><D><G><L><R><L><P><R><T><T><G><T><L><N><V><N><A><L><Q><K><G><T><N><A><A><H><E><A><G><G><Y><K><S><M><D><P><A><K><N><A><E><T><T><N><D><D><D><N><N><V><V><S><L><D><D><P><I><Q><F><T><R><V><S><S><S><S><V><I><S><G><M><S...
MAP4K component of the MAPK pathway required for the mating pheromone response, haploid invasive growth and diploid pseudohyphal development. Links the pheromone response G-protein beta gamma subunits to downstream signaling components. Needed for mating in haploid cells, induction of a mating-specific gene FUS1, induc...
Q03497
P14870
T2F1_PLAOK
Type-2 restriction enzyme FokI
Planomicrobium
<M><V><S><K><I><R><T><F><G><W><V><Q><N><P><G><K><F><E><N><L><K><R><V><V><Q><V><F><D><R><N><S><K><V><H><N><E><V><K><N><I><K><I><P><T><L><V><K><E><S><K><I><Q><K><E><L><V><A><I><M><N><Q><H><D><L><I><Y><T><Y><K><E><L><V><G><T><G><T><S><I><R><S><E><A><P><C><D><A><I><I><Q><A><T><I><A><D><Q><G><N><K><K><G><Y><I><D><N><W><S><S...
An S subtype restriction enzyme that recognizes the asymmetric double-stranded sequence 5'-GGATG-3' and cleaves respectively 14 bases after G-1 (top strand) and 13 bases before C-1 (bottom strand).<BOP>
P14870
Q5E866
APAH_ALIF1
Diadenosine tetraphosphatase
Aliivibrio
<M><A><T><Y><F><V><G><D><I><Q><G><C><L><D><E><L><L><L><L><L><E><R><V><E><F><N><R><E><K><D><Q><L><W><L><T><G><D><L><V><A><R><G><P><K><S><L><E><T><L><R><F><V><K><S><L><G><N><A><A><V><T><I><L><G><N><H><D><L><H><L><L><A><V><S><Q><G><I><S><R><V><K><E><K><D><K><T><A><P><I><F><T><A><P><D><S><E><E><L><L><T><W><L><R><H><Q><P><L...
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.<BOP>
Q5E866
O28278
KAD6_ARCFU
ATP-AMP transphosphorylase
Archaeoglobus
<M><L><I><A><L><T><G><T><P><G><T><G><K><S><S><V><A><E><R><L><R><E><R><G><Y><K><V><A><T><V><V><E><L><A><E><K><H><G><C><I><I><D><E><E><D><G><E><I><V><I><D><V><E><S><L><A><A><R><I><D><F><E><G><I><V><E><G><H><L><S><H><L><L><K><P><D><V><A><I><V><L><R><C><N><P><A><V><L><R><E><R><L><K><G><R><N><W><S><E><E><K><L><L><E><N><L><E...
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.<BOP>
O28278
B5FQM6
ACEK_SALDC
Isocitrate dehydrogenase kinase/phosphatase
Salmonella
<M><P><R><G><L><E><L><L><I><A><Q><T><I><L><Q><G><F><D><A><Q><Y><G><R><F><L><E><V><T><S><G><A><Q><Q><R><F><E><Q><A><D><W><H><A><V><Q><Q><A><M><K><S><R><I><H><L><Y><D><H><H><V><G><L><V><V><E><Q><L><R><C><I><T><D><G><K><S><T><D><A><D><F><L><L><R><V><K><E><H><Y><T><R><L><L><P><D><Y><P><R><F><E><I><A><E><S><F><F><N><S><V><Y...
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully activ...
B5FQM6
Q8SPZ5
RNAS8_AOTTR
Ribonuclease 8
Aotus
<M><A><P><A><R><E><G><C><C><P><L><L><L><L><L><L><L><G><L><W><V><A><E><I><P><V><S><A><K><P><E><G><M><T><S><S><Q><W><F><N><T><Q><H><V><Q><P><S><P><Q><A><C><D><S><A><M><R><D><I><N><K><H><T><K><R><C><K><D><L><N><T><F><L><H><K><P><F><S><S><V><A><A><T><C><Q><T><P><N><I><T><C><K><N><G><H><K><N><C><H><Q><S><H><R><P><V><S><L><T...
Has a low ribonuclease activity.<BOP>
Q8SPZ5
O67241
FLIF_AQUAE
Flagellar M-ring protein
Aquifex
<M><D><K><L><R><E><Y><L><N><L><L><K><E><R><F><N><A><L><T><P><V><Q><K><A><L><A><V><G><I><P><L><L><L><L><S><L><G><A><V><A><L><I><Y><L><S><Q><E><N><Y><T><V><L><Y><T><G><L><S><P><D><D><L><N><A><V><V><T><E><L><D><K><E><G><V><K><Y><K><I><S><P><D><G><R><T><I><Y><V><P><E><N><V><A><R><E><L><R><L><K><L><A><A><K><G><V><P><R><K><G...
The M ring may be actively involved in energy transduction.<BOP>
O67241
Q9FX32
SUS6_ARATH
Sucrose-UDP glucosyltransferase 6
Arabidopsis
<M><S><S><S><S><Q><A><M><L><Q><K><S><D><S><I><A><E><K><M><P><D><A><L><K><Q><S><R><Y><H><M><K><R><C><F><A><S><F><V><G><G><G><K><K><L><M><K><R><E><H><L><M><N><E><I><E><K><C><I><E><D><S><R><E><R><S><K><I><L><E><G><L><F><G><Y><I><L><T><C><T><Q><E><A><A><V><V><P><P><F><V><A><L><A><A><R><P><N><P><G><F><W><E><Y><V><K><V><N><S...
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements.<BOP>
Q9FX32
Q3BVL0
DXR_XANC5
2-C-methyl-D-erythritol 4-phosphate synthase
Xanthomonas
<M><A><G><S><S><L><R><Q><V><A><V><F><G><A><T><G><S><I><G><A><S><A><L><D><V><I><A><R><H><P><E><R><L><R><A><S><L><L><S><A><G><S><K><V><D><E><L><L><A><L><C><A><T><H><R><P><A><H><A><V><I><A><D><A><A><L><Y><P><A><L><R><D><G><L><R><A><L><G><L><A><T><Q><A><H><A><G><A><E><A><L><D><A><L><A><S><G><D><V><C><D><T><V><V><A><A><I><V...
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q3BVL0
A2SU08
DHQS_METLZ
3-dehydroquinate synthase II
Methanocorpusculum
<M><T><I><Q><L><P><P><I><L><I><R><A><D><H><L><Q><T><Y><D><E><R><K><A><I><V><A><S><A><L><E><S><G><Y><T><H><I><I><L><R><P><E><D><E><A><L><R><H><L><G><R><Y><T><A><I><L><A><D><G><K><N><L><M><Y><S><G><E><R><I><G><V><L><L><N><L><T><G><A><E><E><M><E><E><A><Y><S><L><K><N><A><V><P><N><L><I><I><S><P><E><N><W><K><V><I><P><L><E><N...
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.<BOP>
A2SU08
Q1QDH2
RS8_PSYCK
30S ribosomal protein S8
Psychrobacter
<M><S><M><Q><D><T><V><G><D><M><L><T><R><I><R><N><A><Q><M><A><N><K><V><S><V><A><M><P><N><S><K><L><R><K><S><I><A><D><L><L><V><N><E><G><Y><V><A><S><A><V><V><T><E><E><N><N><N><K><A><T><L><T><I><V><L><K><Y><F><E><G><K><A><V><I><E><T><I><Q><R><F><S><R><P><G><L><R><Q><H><R><G><K><D><A><I><P><T><V><K><Q><G><M><G><V><A><I><V><S...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
Q1QDH2
Q8FVV5
FBPC_BRUSU
Fe(3+) ions import ATP-binding protein FbpC
Brucella
<M><T><A><I><R><P><G><S><V><T><F><E><N><V><T><K><K><F><G><N><F><T><A><L><P><N><L><S><L><T><V><E><P><G><T><L><V><T><L><L><G><P><S><G><C><G><K><T><T><T><L><R><L><L><A><G><L><E><H><P><T><S><G><R><I><L><V><G><G><K><D><V><T><N><L><P><A><N><E><R><D><V><S><M><V><F><Q><S><Y><A><L><F><P><H><M><T><S><L><E><N><V><A><Y><G><L><E><S...
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.<BOP>
Q8FVV5
A7FR60
PANB_CLOB1
Ketopantoate hydroxymethyltransferase
Clostridium
<M><R><N><T><V><S><T><F><Q><E><L><K><N><K><G><E><K><I><T><M><L><T><A><Y><D><Y><S><M><A><K><L><I><D><S><S><G><I><N><G><I><L><V><G><D><S><L><G><M><V><C><L><G><Y><E><N><T><L><S><V><T><M><E><D><M><L><H><H><T><K><A><V><V><R><G><T><S><N><A><L><V><V><G><D><M><P><F><M><S><Y><Q><T><S><I><Y><D><A><V><Y><N><A><G><R><F><I><K><E><A...
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.<BOP>
A7FR60
Q9HIS1
RS14Z_THEAC
30S ribosomal protein S14 type Z
Thermoplasma
<M><S><Q><V><K><L><K><P><K><K><K><Y><G><H><I><D><G><C><V><R><C><G><R><K><R><G><I><V><R><R><Y><G><L><H><L><C><R><Q><C><F><R><E><T><A><R><Q><L><G><F><E><K><Y><S>
Binds 16S rRNA, required for the assembly of 30S particles.<BOP>
Q9HIS1
Q4Z4D2
PF36P_PLABA
Sporozoite surface protein Pbs36p
Plasmodium (Vinckeia)
<M><K><R><R><R><I><F><M><Y><Y><C><F><C><F><L><L><K><Y><V><A><F><S><N><V><T><N><P><N><T><T><L><G><H><F><E><I><C><K><I><N><I><Y><S><G><D><A><E><E><C><V><L><E><N><E><F><G><K><M><F><L><F><I><C><D><I><D><Y><N><E><M><S><K><N><I><V><L><P><S><E><C><A><K><K><T><Y><I><D><H><V><N><P><N><G><T><S><P><E><V><N><T><Y><D><I><F><P><D><L...
Involved in sporozoite infection of hepatocytes and replication therein.<BOP>
Q4Z4D2
B4QS37
EI3G2_DROSI
Eukaryotic translation initiation factor 3 subunit 4-2
Sophophora
<M><K><S><F><I><T><S><W><A><D><E><V><D><A><D><Y><V><D><G><L><P><P><S><N><E><Y><I><K><G><D><Y><K><Y><V><T><E><Y><K><F><N><D><D><G><K><K><V><K><V><V><R><T><F><K><I><E><K><Q><I><V><P><K><A><V><A><R><R><R><N><W><V><K><F><G><D><S><R><S><D><K><P><G><P><N><S><Q><T><T><M><A><S><E><E><I><L><M><Q><F><I><G><S><K><E><F><D><Q><T><H...
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and...
B4QS37
Q6LRA1
ZAPC_PHOPR
Cell division protein ZapC
Photobacterium
<M><L><K><P><N><N><S><W><M><W><Y><F><D><L><K><D><N><S><L><M><L><D><L><G><S><D><M><V><F><R><V><G><I><P><A><K><H><L><I><P><S><A><S><E><Q><C><E><F><T><V><D><D><A><S><I><F><Q><N><Y><K><E><N><V><S><H><L><E><I><S><E><P><R><K><A><E><L><A><L><N><A><V><A><A><S><R><F><H><K><P><M><M><P><K><S><W><F><F><D><T><Q><S><V><S><C><D><P><E...
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.<BOP>
Q6LRA1
B2JIA0
GUAA_PARP8
Glutamine amidotransferase
Paraburkholderia
<M><H><D><K><I><L><I><L><D><F><G><S><Q><V><T><Q><L><I><A><R><R><I><R><E><A><H><V><L><S><E><I><H><P><H><D><V><S><D><E><F><I><R><D><F><K><P><T><G><I><I><L><S><G><G><P><N><S><V><T><E><T><D><T><P><R><A><P><Q><A><V><F><E><A><G><V><P><V><L><G><I><C><Y><G><M><Q><T><M><A><E><Q><L><G><G><K><V><D><S><G><H><L><R><E><F><G><Y><A><E...
Catalyzes the synthesis of GMP from XMP.<BOP>
B2JIA0
Q4J9D4
TREH2_SULAC
SaTreH2
Sulfolobus
<M><N><Y><A><L><L><S><N><G><I><T><T><A><L><E><K><E><G><S><I><E><W><F><P><V><P><K><F><D><S><P><S><V><F><T><K><I><L><D><E><D><K><G><G><Y><F><L><I><T><P><E><K><F><N><K><V><K><Q><Q><Y><V><E><Y><S><L><I><L><R><T><E><F><D><D><G><N><L><I><L><I><D><F><L><P><L><S><L><P><A><I><I><R><L><Y><E><A><K><V><P><F><N><V><E><V><K><P><L><F...
Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose.<BOP>
Q4J9D4
Q5XI97
AASD1_RAT
Alanyl-tRNA synthetase domain-containing protein 1
Rattus
<M><A><F><L><C><Q><R><D><S><Y><A><R><E><F><T><T><T><V><V><S><C><C><P><A><E><L><Q><T><D><G><N><G><S><K><K><E><V><L><S><G><F><Q><V><V><L><E><D><T><L><L><F><P><E><G><G><G><Q><P><D><D><R><G><T><I><N><D><I><S><V><L><R><V><T><R><R><G><A><Q><A><D><H><F><T><Q><T><P><L><S><P><G><S><Q><V><Q><V><R><V><D><W><E><R><R><F><D><H><M><Q...
Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala).<BOP>
Q5XI97
P83915
TX21_PHOKE
Neurotoxin PKTx21C2 variant Ala-1 Del
Phoneutria
<A><F><C><K><Y><N><G><E><Q><C><T><S><D><G><Q><C><C><N><G><R><C><R><T><A><F><M><G><K><I><C><M><G>
May act as a neurotoxin.<BOP>
P83915
Q9S2X2
SEPF2_STRCO
Cell division protein SepF 2
Streptomyces albidoflavus group
<M><A><G><A><M><R><K><M><A><V><Y><L><G><L><V><E><D><D><G><Y><D><G><R><G><F><D><P><D><D><D><F><E><P><E><L><D><P><E><P><E><R><D><H><R><R><H><E><P><A><H><Q><S><H><G><A><H><Q><S><Q><R><D><E><E><V><R><V><V><Q><P><P><A><Q><R><E><P><M><P><R><A><A><S><L><A><A><E><S><S><R><P><A><R><I><A><P><V><A><S><I><T><Q><E><R><A><S><L><E><K...
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.<BOP>
Q9S2X2
B5QZ36
HLDE_SALEP
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
Salmonella
<M><K><V><N><L><P><A><F><E><R><A><G><V><M><V><V><G><D><V><M><L><D><R><Y><W><Y><G><P><T><C><R><I><S><P><E><A><P><V><P><V><V><K><V><N><T><V><E><E><R><P><G><G><A><A><N><V><A><M><N><I><A><S><L><G><A><N><A><R><L><V><G><L><T><G><I><D><D><A><A><R><A><L><S><K><T><L><A><E><V><N><V><K><C><D><F><V><S><V><P><T><H><P><T><I><T><K><L...
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.<BOP>
B5QZ36
A4G738
PYRG_HERAR
UTP--ammonia ligase
Herminiimonas
<M><T><K><F><V><F><V><T><G><G><V><V><S><S><L><G><K><G><I><A><A><A><S><L><A><A><I><L><E><S><R><G><L><K><V><T><L><L><K><L><D><P><Y><I><N><V><D><P><G><T><M><S><P><F><Q><H><G><E><V><F><V><T><E><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><I><T><A><K><M><R><K><V><N><N><F><T><T><G><Q><I><Y><E><S><V><I><R><K><E><R><R><G><E><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
A4G738
P9WNV3
LIGD_MYCTU
Polydeoxyribonucleotide synthase [ATP]
Mycobacterium tuberculosis complex
<M><G><S><A><S><E><Q><R><V><T><L><T><N><A><D><K><V><L><Y><P><A><T><G><T><T><K><S><D><I><F><D><Y><Y><A><G><V><A><E><V><M><L><G><H><I><A><G><R><P><A><T><R><K><R><W><P><N><G><V><D><Q><P><A><F><F><E><K><Q><L><A><L><S><A><P><P><W><L><S><R><A><T><V><A><H><R><S><G><T><T><T><Y><P><I><I><D><S><A><T><G><L><A><W><I><A><Q><Q><A><A...
In conjunction with endogenous or Mycobacterium phage Omega Ku (AC Q853W0) can reconstitute NHEJ in Saccharomyces cerevisiae.<BOP>
P9WNV3
Q61212
NPY6R_MOUSE
Pancreatic polypeptide receptor 2
Mus
<M><E><V><L><T><N><Q><P><T><P><N><K><T><S><G><K><S><N><N><S><A><F><F><Y><F><E><S><C><Q><P><P><F><L><A><I><L><L><L><L><I><A><Y><T><V><I><L><I><M><G><I><F><G><N><L><S><L><I><I><I><I><F><K><K><Q><R><E><A><Q><N><V><T><N><I><L><I><A><N><L><S><L><S><D><I><L><V><C><V><M><C><I><P><F><T><V><I><Y><T><L><M><D><H><W><V><F><G><N><T...
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = [Leu-31, Pro-34] NPY > NPY (13-36) > PP. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.<BOP>
Q61212
P36266
NUSG_STRCO
Transcription termination/antitermination protein NusG
Streptomyces albidoflavus group
<M><S><D><P><N><V><N><D><A><I><E><P><V><E><S><V><E><D><E><L><G><T><V><E><G><A><D><N><E><D><T><E><A><S><A><E><A><E><A><A><D><D><T><V><V><A><E><T><D><E><D><A><T><D><A><E><A><D><E><T><A><E><A><T><D><A><E><A><T><E><A><E><A><D><A><D><A><D><A><A><E><A><E><E><S><E><E><E><P><E><A><E><E><P><E><L><D><P><I><E><K><L><R><Q><E><L><R...
Participates in transcription elongation, termination and antitermination.<BOP>
P36266
P31430
DPEP1_RAT
null
Rattus
<M><L><I><I><W><W><F><W><S><L><L><A><I><C><A><S><D><S><F><R><N><Q><A><E><N><I><M><R><T><T><P><V><I><D><G><H><N><D><L><P><W><Q><M><L><T><L><F><N><N><Q><L><R><K><S><E><A><N><L><S><A><L><A><E><T><H><T><N><I><P><K><L><R><A><G><F><V><G><G><Q><F><W><S><A><Y><M><P><C><D><T><Q><N><K><D><A><V><K><R><I><L><E><Q><I><D><V><I><H><R...
Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.<BOP>
P31430
A1SZY2
HLDE_PSYIN
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
Psychromonas
<M><K><I><T><L><P><E><Y><D><K><A><Q><V><L><V><V><G><D><V><M><L><D><R><Y><W><H><G><P><T><A><R><I><S><P><E><A><P><V><P><V><V><K><V><E><Q><I><E><E><R><P><G><G><A><A><N><V><A><L><N><V><A><A><L><G><G><K><V><N><L><I><G><L><V><G><D><D><E><A><A><N><V><L><V><K><N><L><K><S><V><H><V><N><T><D><F><V><S><V><P><N><F><P><T><I><T><K><L...
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.<BOP>
A1SZY2
D4GYH2
AGLI_HALVD
Archaeal glycosylation protein I
Haloferax
<M><A><D><S><P><F><P><C><V><S><V><I><V><P><V><Y><N><D><P><T><G><I><R><D><T><L><T><A><L><T><K><Q><T><Y><P><T><E><R><V><N><I><L><P><I><D><N><G><S><T><D><E><T><R><D><V><I><R><Q><F><E><R><E><H><E><N><V><T><L><V><V><E><D><E><I><Q><G><S><Y><A><A><R><N><T><G><I><E><Q><A><T><G><E><I><F><A><F><V><D><A><D><M><Y><M><D><E><S><W><L...
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins. Catalyzes the addition to the dolichol phosphate carrier of the hexuronic acid found at position 3 of the pentasaccharide.<BOP>
D4GYH2
A6U9C1
GLMU_SINMW
Glucosamine-1-phosphate N-acetyltransferase
Sinorhizobium
<M><E><R><T><C><L><A><I><I><L><A><A><G><E><S><T><R><M><K><S><A><M><S><K><V><L><H><P><V><A><G><R><A><M><I><S><H><V><V><D><A><L><A><S><A><S><I><S><D><V><A><L><V><V><G><R><D><A><E><A><V><A><A><A><A><N><T><G><D><V><A><V><T><A><L><L><Q><K><E><R><L><G><T><A><H><A><V><L><A><A><R><E><A><I><A><K><G><Y><D><D><I><L><V><V><F><G><D...
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ...
A6U9C1
Q9V0N5
DHYS_PYRAB
Probable deoxyhypusine synthase
Pyrococcus
<M><K><A><K><D><I><V><L><K><K><S><E><E><I><E><G><L><A><I><E><G><P><W><L><D><E><V><E><S><L><E><G><V><I><S><Y><Y><E><K><I><G><F><Q><A><T><H><L><G><K><A><V><K><I><W><R><K><V><E><E><K><R><K><G><G><E><E><V><R><V><F><L><G><Y><T><S><N><I><V><S><S><G><L><R><E><I><I><A><W><L><V><K><E><R><K><V><D><V><I><V><T><T><A><G><G><I><E><E...
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.<BOP>
Q9V0N5
Q6FKP2
PAN3_CANGA
Poly(A)-nuclease deadenylation complex subunit 3
Nakaseomyces/Candida clade
<M><D><K><I><N><P><D><W><A><R><D><V><P><C><R><N><V><I><I><Y><G><F><C><K><K><K><T><E><G><C><P><F><K><H><D><D><D><D><I><A><T><P><T><S><T><P><K><V><A><D><T><V><P><A><P><S><G><V><I><Q><Q><P><S><K><I><S><V><S><S><L><P><S><L><N><S><Q><P><S><S><T><A><P><T><S><A><P><N><A><T><A><H><T><G><S><K><S><Q><V><P><K><F><N><A><K><A><S><A...
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened m...
Q6FKP2
P22705
RPOC2_NOSS1
Transcriptase subunit beta'
Nostoc
<M><T><N><E><K><M><I><F><R><N><R><V><V><D><K><G><Q><L><R><N><L><I><S><W><A><F><T><H><Y><G><T><A><R><T><A><V><M><A><D><K><L><K><D><L><G><F><R><Y><A><T><R><A><G><V><S><I><S><V><D><D><L><M><V><P><P><S><K><R><S><L><L><E><A><A><E><E><E><I><R><A><T><E><V><R><Y><Q><R><G><E><I><T><E><V><E><R><F><Q><K><V><I><D><T><W><N><G><T><S...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
P22705
B3EK98
NUOD_CHLPB
NDH-1 subunit D
Chlorobium
<M><Q><E><L><G><K><A><E><H><T><S><I><R><V><T><P><Q><G><E><N><R><V><I><V><E><K><D><L><S><S><E><E><M><I><L><N><M><G><P><Q><H><P><S><T><H><G><V><L><R><L><E><C><K><T><D><G><E><V><V><I><E><A><E><P><Y><L><G><Y><L><H><R><C><F><E><K><H><A><E><M><V><D><Y><P><G><I><V><P><F><V><D><R><M><D><Y><L><A><S><M><N><N><D><F><A><Y><C><I><A...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar...
B3EK98
A5GPF9
SYA_SYNPW
Alanyl-tRNA synthetase
unclassified Synechococcus
<M><A><V><A><R><S><S><R><T><D><A><A><R><P><R><T><G><A><E><I><R><D><A><F><L><A><F><F><E><E><R><G><H><K><R><M><P><S><A><S><L><V><P><E><D><P><T><V><L><L><T><I><A><G><M><L><P><F><K><P><I><F><L><G><Q><Q><E><R><P><A><P><C><A><T><S><S><Q><K><C><I><R><T><N><D><I><E><N><V><G><R><T><A><R><H><H><T><F><F><E><M><L><G><N><F><S><F><G...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
A5GPF9
Q60948
MAD4_MOUSE
Max-interacting transcriptional repressor MAD4
Mus
<M><E><L><N><S><L><L><L><L><L><E><A><A><E><Y><L><E><R><R><D><R><E><A><E><H><G><Y><A><S><M><L><P><F><D><G><D><F><A><R><K><K><T><K><T><A><G><L><V><R><K><G><P><N><N><R><S><S><H><N><E><L><E><K><H><R><R><A><K><L><R><L><Y><L><E><Q><L><K><Q><L><G><P><L><G><P><D><S><T><R><H><T><T><L><S><L><L><K><R><A><K><M><H><I><K><K><L><E><E...
Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.<BOP>
Q60948
B8E4W4
LIPA_SHEB2
Sulfur insertion protein LipA
Shewanella
<M><N><R><P><E><R><L><Q><P><G><V><K><L><R><D><A><D><K><V><S><R><I><P><V><K><I><V><P><S><E><R><D><T><M><L><R><K><P><D><W><L><R><V><K><L><P><A><S><N><Q><R><I><L><E><I><K><Q><A><L><R><K><N><G><L><H><S><V><C><E><E><A><S><C><P><N><L><A><E><C><F><N><H><G><T><A><T><F><M><I><L><G><A><I><C><T><R><R><C><P><F><C><D><V><A><H><G><R...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
B8E4W4
Q0AK66
RBFA_MARMM
Ribosome-binding factor A
Maricaulis
<M><A><R><R><Q><T><H><T><S><K><G><P><S><Q><R><Q><L><R><A><G><E><L><V><R><H><A><L><V><G><I><I><A><R><E><E><F><R><D><P><D><L><E><G><Q><M><I><S><V><T><E><V><R><P><S><P><D><L><R><V><A><K><V><Y><V><A><P><L><G><R><G><D><S><A><K><L><A><A><G><L><N><R><C><A><A><F><L><R><G><R><L><G><R><E><I><E><M><K><F><T><P><E><L><H><F><H><A><D...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
Q0AK66
P66920
THIE2_STRPN
Thiamine-phosphate pyrophosphorylase 2
Streptococcus
<M><N><R><E><A><L><R><L><Y><L><V><T><N><R><Y><Q><D><S><V><E><S><F><L><A><K><V><E><T><A><C><R><S><G><V><T><I><V><Q><L><R><E><K><N><L><T><T><N><Q><Y><Y><Q><L><A><K><Q><V><K><E><I><T><D><A><Y><Q><V><P><L><I><I><D><D><R><L><D><V><C><L><A><V><D><A><A><G><L><H><I><G><D><D><E><L><P><V><S><V><A><R><K><V><L><G><P><E><K><I><L><G...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
P66920
B0TF85
DTD_HELMI
Gly-tRNA(Ala) deacylase
Heliomicrobium
<M><R><A><L><I><Q><R><V><L><R><G><R><V><T><V><E><G><S><E><V><G><A><I><G><P><G><L><V><V><L><V><G><A><G><Q><G><D><G><E><A><D><A><R><Y><V><A><E><K><I><A><H><L><R><I><F><E><D><E><Q><G><K><M><N><R><S><V><S><D><V><G><G><E><V><L><V><V><S><Q><F><T><L><Y><G><D><C><R><K><G><R><R><P><S><F><T><Q><A><A><P><P><D><E><A><R><R><L><V><E...
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec...
B0TF85
A3PEY3
IF2_PROM0
Translation initiation factor IF-2
Prochlorococcus
<M><T><I><S><D><K><I><R><I><Y><E><L><S><R><D><L><N><L><E><N><K><D><I><L><D><A><A><Q><K><L><S><I><S><V><K><S><H><S><S><S><I><S><A><E><E><A><K><K><I><K><N><L><I><N><K><K><N><S><D><K><K><I><L><S><I><N><K><P><S><I><K><K><D><N><F><K><Q><N><K><S><P><S><I><S><S><K><K><E><T><P><L><K><D><N><S><N><K><K><P><L><L><I><K><P><L><N><K...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
A3PEY3
B0USH2
PROA_HISS2
Glutamyl-gamma-semialdehyde dehydrogenase
Histophilus
<M><S><L><K><E><M><G><K><N><A><K><Q><A><A><T><I><L><A><Q><L><S><Q><Q><Q><K><N><T><A><L><Q><I><I><A><E><Q><L><E><L><Q><S><D><K><I><L><V><E><N><A><K><D><I><Q><L><A><K><E><N><G><L><S><D><A><I><I><D><R><L><L><L><T><K><E><R><I><N><S><I><A><K><D><V><R><H><I><I><S><L><S><D><P><I><G><Q><I><I><D><G><G><I><L><E><S><G><T><K><L><E...
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP>
B0USH2
A5VNW2
ATP6_BRUO2
F-ATPase subunit 6
Brucella
<M><A><N><D><P><I><H><Q><F><Q><V><S><R><W><I><P><I><D><V><G><G><V><D><L><S><F><T><N><V><S><A><F><M><V><A><T><V><V><L><A><S><G><F><L><Y><L><T><S><S><G><R><G><L><I><P><T><R><L><Q><S><V><S><E><M><A><Y><E><F><V><A><T><S><L><R><D><S><A><G><S><K><G><M><K><F><F><P><F><V><F><S><L><F><M><F><V><L><V><A><N><F><I><G><L><F><P><Y><F...
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP>
A5VNW2
A3PF25
RPOA_PROM0
Transcriptase subunit alpha
Prochlorococcus
<M><L><Q><Y><Q><I><E><R><I><D><H><Q><I><A><D><D><R><S><Q><T><G><T><F><L><I><G><P><L><E><R><G><Q><A><T><T><L><G><N><S><L><R><R><V><L><M><G><G><L><E><G><S><A><V><T><A><V><R><I><A><G><I><N><H><E><Y><A><T><I><P><G><V><R><E><D><V><L><D><I><L><L><N><C><K><Q><L><S><I><N><S><T><N><P><E><L><E><I><G><R><L><V><A><S><G><P><M><E><V...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A3PF25
B0TQP2
LPXC_SHEHH
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase
Shewanella
<M><I><F><Q><R><T><V><K><E><M><V><K><T><T><G><V><G><L><H><S><G><N><K><V><T><L><T><I><K><P><A><P><V><N><T><G><I><K><L><V><R><T><D><L><S><P><A><V><E><I><P><A><V><A><D><Q><V><R><E><T><T><M><C><T><A><L><V><N><D><D><G><V><R><I><S><T><I><E><H><L><F><A><A><L><A><G><L><G><I><D><N><A><V><I><E><V><D><A><P><E><I><P><I><M><D><G><S...
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.<BOP>
B0TQP2
B4U0X9
RS14_STREM
30S ribosomal protein S14
Streptococcus
<M><A><K><K><S><K><I><A><K><Y><H><K><Q><L><Q><L><I><E><Q><Y><A><D><L><R><R><E><L><K><A><K><G><D><Y><E><A><L><R><K><L><P><R><D><S><N><P><N><R><L><K><N><R><D><R><I><D><G><R><P><H><A><Y><M><R><K><F><G><V><S><R><I><N><F><R><E><L><A><H><K><G><Q><L><P><G><I><T><K><A><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
B4U0X9
A7ZNW5
CDD_ECO24
Cytidine aminohydrolase
Escherichia
<M><H><P><R><F><Q><T><A><F><A><Q><L><A><D><N><L><Q><S><A><L><E><P><I><L><A><D><K><Y><F><P><A><L><L><T><G><E><Q><V><S><S><L><K><S><A><T><G><L><D><E><D><A><L><A><F><A><L><L><P><L><A><A><A><C><A><R><T><P><L><S><N><F><N><V><G><A><I><A><R><G><V><S><G><T><W><Y><F><G><A><N><M><E><F><I><G><A><T><M><Q><Q><T><V><H><A><E><Q><S><A...
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.<BOP>
A7ZNW5
P15925
FPGS_LACCA
Tetrahydrofolylpolyglutamate synthase
Lacticaseibacillus
<M><N><Y><T><E><T><V><A><Y><I><H><S><F><P><R><L><A><K><T><G><D><H><R><R><I><L><T><L><L><H><A><L><G><N><P><Q><Q><Q><G><R><Y><I><H><V><T><G><T><N><G><K><G><S><A><A><N><A><I><A><H><V><L><E><A><S><G><L><T><V><G><L><Y><T><S><P><F><I><M><R><F><N><E><R><I><M><I><D><H><E><P><I><P><D><A><A><L><V><N><A><V><A><F><V><R><A><A><L><E...
Involved in the conversion of folates to polyglutamate derivatives, and likely functions in the retention of cellular folate pools. Catalyzes successive MgATP-dependent additions of glutamate to a pteroylmonoglutamate substrate, with a high preference for 5,10-methylenetetrahydrofolate (mTHF). Thus, metabolizes mTHF to...
P15925
A1ASB3
PYRDB_PELPD
Orotate reductase (NADH)
Pelobacter
<M><K><P><D><M><T><V><N><L><A><G><L><E><L><R><N><P><V><M><T><A><S><G><T><F><G><Y><G><R><E><F><A><D><Y><V><D><L><E><K><I><G><A><F><V><T><K><G><L><S><L><K><P><R><P><G><N><P><T><P><R><I><V><E><T><P><G><G><M><L><N><A><I><G><L><Q><N><V><G><I><E><A><F><I><A><E><K><V><P><F><L><A><R><V><N><T><P><A><I><V><N><F><F><G><S><T><P><E...
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.<BOP>
A1ASB3
Q2L1H6
UBIC_BORA1
Probable chorismate pyruvate-lyase
Bordetella
<M><T><T><K><Y><Q><A><P><L><A><A><G><W><L><I><R><A><P><S><L><L><S><P><T><Q><R><H><W><L><F><R><P><G><A><L><T><A><G><L><R><Q><L><G><K><V><Q><L><R><V><V><S><E><H><A><E><G><A><S><L><D><E><A><R><A><M><L><I><A><P><G><S><P><V><W><V><R><E><V><L><M><S><V><D><G><I><D><S><V><P><A><R><S><L><T><P><L><A><A><S><H><G><S><W><Q><G><M><R...
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.<BOP>
Q2L1H6
P10054
RL1_PROVU
50S ribosomal protein L1
Proteus
<M><A><K><L><T><K><R><M><R><N><I><R><E><K><V><E><V><T><K><Q><Y><E><I><A><E><A><V><A><L><L><K><E><L><A><T><A><K><F><V><E><S><V><D><V><A><V><N><L><G><I><D><A><R><K><S><D><Q><N><V><R><G><A><T><V><L><P><H><G><T><G><R><S><V><R><V><A><V><F><A><Q><G><A><N><A><E><A><A><K><E><A><G><A><E><L><V><G><M><D><D><L><A><A><K><V><K><A><G...
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP>
P10054
Q8M893
NU1M_EMBAL
NADH dehydrogenase subunit 1
Emballonura
<M><F><L><V><N><L><L><L><M><I><I><P><I><L><L><A><V><A><F><L><T><L><L><E><R><K><T><L><G><Y><M><Q><L><R><K><G><P><N><I><V><G><P><H><G><L><L><Q><P><I><A><D><A><I><K><L><F><T><K><E><P><L><R><P><L><T><S><S><T><S><M><F><I><M><A><P><I><L><A><L><S><L><A><L><T><M><W><T><P><L><P><M><P><Y><P><L><I><N><M><N><L><G><V><L><F><I><L><A...
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP>
Q8M893
Q0UQV6
BST1_PHANO
GPI inositol-deacylase
Parastagonospora
<M><V><R><E><K><A><Q><V><T><M><G><S><T><T><M><D><M><L><E><D><E><V><V><K><A><Q><D><R><R><W><R><L><R><L><R><N><P><W><A><C><S><A><Y><T><L><V><T><T><A><L><G><F><A><A><F><F><L><M><L><Q><S><F><L><T><K><Q><L><D><T><K><G><C><E><M><V><Y><M><R><P><M><Y><S><K><F><D><D><F><D><T><E><H><T><R><F><A><S><K><Y><S><L><Y><L><Y><R><E><W><G...
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.<BOP>
Q0UQV6
A5IJ44
COAD_THEP1
Pantetheine-phosphate adenylyltransferase
Thermotoga
<M><K><A><V><Y><P><G><S><F><D><P><I><T><L><G><H><V><D><I><I><K><R><A><L><S><I><F><D><E><L><V><V><L><V><T><E><N><P><R><K><K><C><M><F><T><L><E><E><R><K><K><L><I><E><E><V><L><S><D><L><S><G><V><K><V><D><V><H><H><G><L><L><V><D><Y><L><K><K><H><G><I><K><V><L><V><R><G><L><R><A><V><T><D><Y><E><Y><E><L><Q><M><A><L><A><N><K><K><L...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
A5IJ44
A0PZH1
MINE_CLONN
Cell division topological specificity factor
Clostridium
<M><D><L><F><K><L><F><S><G><K><P><S><S><K><E><V><A><K><D><R><L><K><L><I><L><I><H><D><R><S><S><I><A><P><E><L><L><E><V><M><K><S><D><I><L><K><V><I><S><K><Y><V><I><I><D><D><D><E><V><E><V><R><L><T><K><T><E><E><V><D><A><S><S><P><A><L><I><A><S><I><P><I><K><K><M><K><Q><R>
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.<BOP>
A0PZH1
Q889E3
LSPA_PSESM
Signal peptidase II
Pseudomonas
<M><P><D><A><T><L><S><N><T><S><L><G><R><L><A><W><L><W><L><T><V><L><I><V><A><V><D><Q><V><S><K><Y><Y><F><E><N><A><L><S><L><Y><Q><Q><I><I><V><I><P><D><Y><F><S><W><T><L><A><Y><N><T><G><A><A><F><S><F><L><A><D><G><A><G><W><Q><R><W><L><F><A><L><I><A><V><V><V><S><A><V><L><V><V><W><L><K><R><L><G><R><D><D><T><W><L><A><I><A><L><A...
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP>
Q889E3
Q8WML3
KAT6B_MACFA
MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4
Macaca
<M><V><K><L><A><N><P><L><Y><T><E><W><I><L><E><A><I><Q><K><I><K><K><Q><K><Q><R><P><S><E><E><R><I><C><H><A><V><S><T><S><H><G><L><D><K><K><T><V><S><E><Q><L><E><L><S><V><Q><D><G><S><V><L><K><V><T><N><K><G><L><A><S><Y><K><D><P><D><N><P><G><R><F><S><S><V><K><P><G><T><F><P><K><S><T><K><E><S><R><G><S><C><N><D><L><R><N><V><D><W...
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<BOP>
Q8WML3
C1DCY1
PLSY_LARHH
Lysophosphatidic acid synthase
Laribacter
<M><T><T><I><A><S><L><V><L><A><Y><L><L><G><S><V><P><F><A><V><L><V><S><L><G><M><G><L><A><D><P><R><S><Y><G><S><G><N><P><G><A><T><N><V><L><R><S><G><N><K><L><A><A><L><L><T><L><L><G><D><A><A><K><G><W><L><A><V><W><L><A><Q><T><Y><G><A><S><F><G><L><A><A><P><E><I><A><M><V><G><L><A><V><F><I><G><H><L><W><P><V><F><L><A><F><R><G><G...
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP>
C1DCY1
A8GB06
CRCB_SERP5
Putative fluoride ion transporter CrcB
Serratia
<M><L><S><S><L><L><A><V><F><I><G><G><G><M><G><S><V><L><R><W><A><I><S><M><K><M><N><P><L><N><A><H><I><P><L><G><T><L><A><V><N><L><L><G><G><F><I><I><G><L><A><I><A><I><F><S><R><L><T><H><L><D><P><T><W><K><L><L><I><T><T><G><F><C><G><G><L><T><T><F><S><T><F><S><L><E><V><V><Y><L><L><Q><D><G><R><F><M><W><A><L><A><N><M><L><L><N><L...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
A8GB06
B8HA70
MSRA_PSECP
Peptide-methionine (S)-S-oxide reductase
Pseudarthrobacter
<M><K><T><F><V><L><G><G><G><C><F><W><C><L><D><A><V><Y><Q><K><T><K><G><V><T><A><V><V><S><G><Y><T><G><G><H><D><P><Y><P><D><Y><Y><S><V><C><S><G><T><T><G><H><A><E><V><V><A><V><T><F><D><E><E><I><I><P><A><E><V><I><L><D><M><F><F><A><L><H><D><P><T><T><L><N><R><Q><G><Y><D><V><G><T><Q><Y><R><S><S><M><F><Y><E><T><T><E><E><K><I><L...
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.<BOP>
B8HA70
B2TQ14
THIM_CLOBB
4-methyl-5-beta-hydroxyethylthiazole kinase
Clostridium
<M><I><N><E><I><L><D><K><V><V><R><L><L><E><E><V><R><A><K><K><P><L><V><H><S><I><T><N><Y><I><T><A><T><D><C><A><N><V><I><L><A><V><G><G><S><P><T><M><A><D><Y><V><K><E><V><E><E><I><A><S><I><S><S><A><V><V><L><N><M><G><V><I><S><D><G><M><V><E><S><M><I><L><A><G><K><S><A><N><K><N><N><V><P><V><I><F><D><P><V><G><A><G><V><A><N><F><R...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
B2TQ14
P28072
PSB6_HUMAN
Proteasome subunit Y
Homo
<M><A><A><T><L><L><A><A><R><G><A><G><P><A><P><A><W><G><P><E><A><F><T><P><D><W><E><S><R><E><V><S><T><G><T><T><I><M><A><V><Q><F><D><G><G><V><V><L><G><A><D><S><R><T><T><T><G><S><Y><I><A><N><R><V><T><D><K><L><T><P><I><H><D><R><I><F><C><C><R><S><G><S><A><A><D><T><Q><A><V><A><D><A><V><T><Y><Q><L><G><F><H><S><I><E><L><N><E><P...
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participate...
P28072
Q5XE09
G6PI_STRP6
Phosphohexose isomerase
Streptococcus
<M><S><H><I><T><F><D><Y><S><K><V><L><E><S><F><A><G><Q><H><E><I><D><F><L><Q><G><Q><V><T><E><A><D><K><L><L><R><E><G><T><G><P><G><S><D><F><L><G><W><L><D><L><P><E><N><Y><D><K><E><E><F><A><R><I><L><T><A><A><E><K><I><K><A><D><S><E><V><L><V><V><I><G><I><G><G><S><Y><L><G><A><K><A><A><I><D><F><L><N><H><H><F><A><N><L><Q><T><A><K...
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP>
Q5XE09
Q6AC71
DCDB_LEIXX
DCD-DUT
Leifsonia
<M><L><L><S><D><R><D><I><K><A><E><L><T><A><G><R><L><G><L><E><P><F><E><Q><G><M><I><Q><P><S><S><V><D><V><R><L><D><R><F><F><R><L><F><D><N><H><K><Y><P><F><I><D><P><A><E><D><Q><P><D><L><T><R><F><V><E><V><V><A><D><Q><P><F><I><L><H><P><G><E><F><V><L><G><S><T><F><E><L><V><S><L><P><D><D><V><A><A><R><L><E><G><K><S><S><L><G><R><L...
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.<BOP>
Q6AC71
A4F804
ENO_SACEN
2-phosphoglycerate dehydratase
Saccharopolyspora
<M><A><I><I><E><Q><V><G><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><E><V><A><L><E><D><G><T><L><T><R><A><A><V><P><S><G><A><S><T><G><E><H><E><A><V><E><L><R><D><G><D><A><E><R><Y><G><G><K><G><V><E><K><A><V><E><A><V><L><D><E><I><G><P><E><L><A><G><V><D><A><I><E><Q><R><V><V><D><Q><K><L><V><D><L><D><G><T><P><D><K><S><R><L><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
A4F804
Q9Z7E9
FOLB_CHLPN
7,8-dihydroneopterin aldolase
Chlamydia
<M><I><A><I><E><R><Y><Q><L><I><I><S><K><F><R><M><W><L><F><L><G><C><S><V><E><E><R><H><F><K><Q><P><V><L><I><S><V><T><F><S><Y><N><E><V><P><S><A><C><L><S><D><K><L><S><D><A><C><C><Y><L><E><V><T><S><L><I><E><E><I><A><N><T><K><P><Y><A><L><I><E><H><L><A><N><E><L><F><D><S><L><V><I><S><F><G><D><K><A><S><K><I><D><L><E><V><E><K><E...
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.<BOP>
Q9Z7E9
A9BHV0
ENGB_PETMO
Probable GTP-binding protein EngB
Petrotoga
<M><K><V><Y><K><A><Q><L><I><K><T><V><Y><K><I><E><D><L><P><P><P><D><K><K><E><I><A><F><A><G><R><S><N><V><G><K><S><S><F><L><N><A><I><L><G><I><K><I><A><K><V><S><S><T><P><G><K><T><R><S><I><N><Y><Y><L><V><N><D><K><Y><Y><F><V><D><L><P><G><Y><G><F><A><S><V><S><K><Q><E><K><E><R><W><N><V><L><M><N><E><Y><F><K><T><R><F><S><L><S><A...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
A9BHV0
B5FTI4
RSMF_SALDC
rRNA (cytosine-C(5)-)-methyltransferase RsmF
Salmonella
<M><A><Q><H><A><V><Y><F><P><D><A><F><L><T><Q><M><R><E><A><M><P><S><T><L><S><F><D><E><F><I><S><A><C><Q><R><P><L><R><R><S><I><R><I><N><T><L><K><I><S><V><A><D><F><L><A><L><I><A><P><Y><G><W><S><L><T><P><I><P><W><C><H><E><G><F><W><I><E><R><D><D><E><E><A><L><P><L><G><S><T><A><E><H><L><S><G><L><F><Y><I><Q><E><A><S><S><M><L><P...
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.<BOP>
B5FTI4
B0S2F7
KTHY_FINM2
dTMP kinase
Finegoldia
<M><F><I><T><F><E><G><P><D><G><S><G><K><S><T><I><I><Q><K><V><Y><D><Y><L><I><E><N><N><Y><D><V><I><K><T><R><E><P><G><G><S><P><I><A><E><K><I><R><N><L><I><L><D><T><E><N><I><K><M><G><Y><R><T><E><A><L><L><Y><A><A><S><R><A><Q><H><V><E><E><T><I><L><P><A><L><N><E><N><K><I><V><L><C><D><R><F><L><I><S><S><L><A><Y><Q><G><V><G><R><G...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
B0S2F7
Q21179
NAS18_CAEEL
Nematode astacin 18
Caenorhabditis
<M><C><A><S><C><L><H><N><A><N><A><A><S><F><L><M><E><T><F><S><R><H><R><L><N><F><I><C><I><G><K><M><N><I><F><Y><N><V><T><S><L><D><N><K><Y><S><F><H><N><P><S><A><P><V><P><H><S><S><H><A><L><S><S><R><Q><A><H><F><T><S><F><R><A><P><V><A><P><P><S><R><P><R><R><S><Q><L><P><S><S><A><K><L><L><Y><C><F><D><S><S><F><S><T><E><K><R><E><L...
Metalloprotease.<BOP>
Q21179
Q98KL7
KUP2_RHILO
Probable potassium transport system protein kup 2
Mesorhizobium
<M><D><L><A><S><R><D><S><E><A><E><T><V><E><Q><S><S><H><S><G><A><E><Q><H><S><T><K><V><L><M><L><G><A><L><G><V><V><Y><G><D><I><G><T><S><P><I><Y><A><F><R><E><A><L><H><A><S><P><G><I><D><T><R><A><Q><V><L><G><V><L><S><L><I><V><W><A><L><T><I><I><V><T><I><K><Y><V><A><F><V><L><R><A><D><N><K><G><E><G><G><T><L><S><L><M><S><L><A><R...
Transport of potassium into the cell.<BOP>
Q98KL7
C5CP50
RL2_VARPS
50S ribosomal protein L2
Variovorax
<M><A><V><I><K><M><K><P><T><S><P><G><Q><R><G><A><V><K><I><S><R><D><H><L><F><K><G><A><P><H><A><P><L><L><E><P><Q><F><Q><K><A><G><R><N><N><N><G><H><I><T><I><R><H><R><G><G><G><A><K><H><H><Y><R><V><V><D><F><V><R><N><K><D><G><I><P><A><K><V><E><R><I><E><Y><D><P><N><R><T><A><H><I><A><L><V><C><Y><A><D><G><E><R><R><Y><I><I><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
C5CP50
A6V0K2
RF3_PSEA7
Peptide chain release factor 3
Pseudomonas
<M><T><T><Q><A><A><E><V><A><K><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><K><L><L><L><M><G><K><A><I><A><V><A><G><T><V><K><S><R><K><S><D><R><H><A><T><S><D><W><M><E><M><E><K><Q><R><G><I><S><I><T><T><S><V><M><Q><F><P><Y><R><E><H><M><I><N><L><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><T><A><V><D><S><A...
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP>
A6V0K2
A0KN93
RLMH_AERHH
rRNA (pseudouridine-N3-)-methyltransferase RlmH
Aeromonas
<M><K><I><Q><L><I><A><V><G><T><K><M><P><A><W><V><E><H><G><F><E><E><Y><R><R><R><F><P><K><D><M><P><F><E><L><V><E><I><G><A><G><K><R><G><K><N><A><D><I><P><R><I><L><Q><K><E><G><E><A><M><L><A><A><A><G><R><S><R><I><V><T><L><D><I><P><G><K><P><W><T><T><E><Q><L><A><V><Q><L><E><A><W><K><L><D><G><R><D><V><A><L><L><V><G><G><P><E><G...
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP>
A0KN93
Q7MYH5
RPOA_PHOLL
Transcriptase subunit alpha
Photorhabdus
<M><Q><G><S><V><T><E><F><L><K><P><R><L><V><D><I><E><Q><V><S><S><T><H><A><K><V><T><L><E><P><L><E><R><G><F><G><H><T><L><G><N><A><L><R><R><I><L><L><S><S><M><P><G><C><A><V><T><E><V><E><I><D><G><V><L><H><E><Y><S><T><K><E><G><V><Q><E><D><I><L><E><I><L><L><N><L><K><G><L><A><V><R><V><Q><G><K><D><E><V><I><L><T><L><N><K><S><G><I...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q7MYH5
Q8YDB0
DAPE_BRUME
N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Brucella
<M><T><L><P><V><N><P><V><D><N><L><A><A><L><I><R><C><P><S><V><T><P><A><E><G><G><A><L><T><A><L><E><K><M><L><K><L><M><G><F><S><A><N><R><P><V><F><S><D><D><N><T><P><D><I><E><N><L><Y><A><R><K><S><G><N><G><P><H><L><M><F><A><G><H><T><D><V><V><P><P><G><D><E><K><D><W><K><H><P><P><F><A><A><A><I><E><D><G><V><M><Y><G><R><G><A><V><D...
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP>
Q8YDB0
A6TD39
ISPD_KLEP7
MEP cytidylyltransferase
Klebsiella
<M><A><A><T><F><P><G><V><C><A><V><V><P><A><A><G><F><G><R><R><M><Q><T><E><C><P><K><Q><Y><L><S><I><G><N><K><T><I><L><E><H><A><V><A><A><L><L><A><D><A><R><V><Q><R><V><V><I><A><V><S><P><G><D><R><R><F><S><Q><L><P><L><A><Q><H><P><Q><I><T><V><V><D><G><G><A><E><R><A><D><S><V><L><A><G><L><Q><A><L><P><E><A><Q><W><V><L><V><H><D><A...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
A6TD39
Q3AHM2
ATPB_SYNSC
F-ATPase subunit beta
unclassified Synechococcus
<M><V><A><S><A><P><A><S><A><G><T><K><G><V><I><R><Q><V><I><G><P><V><L><D><V><E><F><P><A><G><K><L><P><K><I><Y><N><A><L><R><I><E><G><K><N><P><A><G><D><D><V><A><L><T><A><E><V><Q><Q><L><L><G><D><H><R><V><R><A><V><A><M><S><G><T><D><G><L><V><R><G><M><E><A><V><D><T><G><A><P><I><S><V><P><V><G><E><G><T><L><G><R><I><F><N><V><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q3AHM2
P0AFY7
SBMA_ECO57
Peptide antibiotic transporter SbmA
Escherichia
<M><F><K><S><F><F><P><K><P><G><T><F><F><L><S><A><F><V><W><A><L><I><A><V><I><F><W><Q><A><G><G><G><D><W><V><A><R><I><T><G><A><S><G><Q><I><P><I><S><A><A><R><F><W><S><L><D><F><L><I><F><Y><A><Y><Y><I><V><C><V><G><L><F><A><L><F><W><F><I><Y><S><P><H><R><W><Q><Y><W><S><I><L><G><T><A><L><I><I><F><V><T><W><F><L><V><E><V><G><V><A...
Uptake of antimicrobial peptides.<BOP>
P0AFY7
Q2G8W3
RS5_NOVAD
30S ribosomal protein S5
Novosphingobium
<M><A><D><E><T><N><L><E><G><V><A><A><V><E><A><T><G><G><E><P><Q><R><E><G><R><G><R><G><R><G><R><G><G><N><D><R><G><G><E><R><G><G><R><G><R><R><D><D><R><R><G><R><G><N><N><D><E><E><G><G><E><E><L><I><E><K><L><V><H><I><N><R><V><S><K><T><V><K><G><G><K><R><F><G><F><A><A><L><V><V><V><G><D><G><K><G><R><A><G><F><G><K><G><K><A><R><E...
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP>
Q2G8W3
Q7M8F5
RS11_WOLSU
30S ribosomal protein S11
Wolinella
<M><A><K><R><K><V><T><N><K><K><R><V><V><K><K><N><I><A><R><G><I><I><H><I><A><A><T><F><N><N><T><S><V><T><I><T><D><E><M><G><N><V><I><C><W><S><T><A><G><A><L><G><F><K><G><S><K><K><S><T><P><Y><A><A><Q><Q><A><V><E><D><A><V><V><K><A><K><E><H><G><I><K><E><L><G><I><K><V><Q><G><P><G><S><G><R><E><T><A><V><K><S><L><G><S><I><E><G><I...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
Q7M8F5
A1K5T8
SSRP_AZOSB
Small protein B
Azoarcus
<M><S><I><I><D><N><R><K><A><Y><H><D><Y><F><I><E><E><K><Y><E><A><G><L><V><L><E><G><W><E><V><K><A><I><R><A><G><R><A><N><I><K><E><A><Y><I><I><V><R><G><E><E><I><F><I><L><G><M><H><I><T><P><L><A><S><A><S><T><H><I><R><T><D><P><T><R><T><R><K><L><L><L><H><G><A><E><I><A><R><L><I><G><K><V><E><R><A><G><F><T><L><V><P><L><D><L><H><Y...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
A1K5T8
Q8NJQ5
CHI37_TRIHA
Chitinase 37
Trichoderma
<M><T><R><L><L><D><A><S><F><L><L><L><P><V><I><A><S><T><L><F><G><T><A><S><A><Q><S><T><C><A><T><K><G><K><P><A><G><K><V><L><Q><G><Y><W><E><N><W><D><G><S><A><N><G><V><H><P><G><F><G><W><T><P><I><E><N><P><V><I><A><Q><N><G><Y><N><V><I><N><A><A><F><P><V><I><L><S><D><G><T><A><L><W><E><D><G><M><D><A><T><V><K><V><A><T><P><A><E><M...
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Plays a morphogenetic role during apical growth, cell division and differentiation (cell wall morphogenesis). May be involved in the degradation and...
Q8NJQ5