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license: mit
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---
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Out of **20,577** human proteins (from [UniProt human proteome](https://www.uniprot.org/proteomes/UP000005640)), sequences shorter than 20 amino acids or longer than 512 amino acids were removed, resulting in a set of **12,703** proteins. The uShuffle algorithm ([python pacakge](https://github.com/guma44/ushuffle)) was then used to shuffle these protein sequences while maintaining their doublet distribution. The very few sequences for which uShuffle failed to create a shuffled version were eliminated.
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Afterwards, h-CD-HIT algorithm ([web server](http://weizhong-lab.ucsd.edu/cdhit-web-server/cgi-bin/index.cgi)) was used with three subsequent filter stages at pairwise identity cutoffs of 0.9, 0.5 and 0.1, resulting in a total of **11,658** sequences.
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license: mit
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---
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# Dataset Description
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Out of **20,577** human proteins (from [UniProt human proteome](https://www.uniprot.org/proteomes/UP000005640)), sequences shorter than 20 amino acids or longer than 512 amino acids were removed, resulting in a set of **12,703** proteins. The uShuffle algorithm ([python pacakge](https://github.com/guma44/ushuffle)) was then used to shuffle these protein sequences while maintaining their doublet distribution. The very few sequences for which uShuffle failed to create a shuffled version were eliminated.
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Afterwards, h-CD-HIT algorithm ([web server](http://weizhong-lab.ucsd.edu/cdhit-web-server/cgi-bin/index.cgi)) was used with three subsequent filter stages at pairwise identity cutoffs of 0.9, 0.5 and 0.1, resulting in a total of **11,658** sequences.
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# Citation
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If you use this dataset, please cite our paper:
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```
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@article {
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author = {Geffen, Yaron and Ofran, Yanay and Unger, Ron},
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title = {DistilProtBert: A distilled protein language model used to distinguish between real proteins and their randomly shuffled counterparts},
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year = {2022},
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doi = {10.1101/2022.05.09.491157},
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URL = {https://www.biorxiv.org/content/early/2022/05/10/2022.05.09.491157},
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eprint = {https://www.biorxiv.org/content/early/2022/05/10/2022.05.09.491157.full.pdf},
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journal = {bioRxiv}
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}
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```
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