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### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "granisetron", "palonosetron" ], "relation": "non_comb" } ] ### Output ### ID 1
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "naproxen", "celecoxib", "rofecoxib" ], "relation": "non_comb" } ] ### Output ### ID 2
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "vincristine", "methotrexate" ], "relation": "COMB" } ] ### Output ### ID 3
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "omeprazole", "clopidogrel" ], "relation": "NEG" } ] ### Output ### ID 4
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cyclophosphamide", "rituximab", "pentostatin" ], "relation": "POS" } ] ### Output ### ID 5
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "isoniazid", "rifapentine" ], "relation": "POS" } ] ### Output ### ID 6
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "docetaxel", "vinblastine", "doxorubicin", "cisplatin", "paclitaxel", "docetaxel", "vinblastine" ], "relation": "non_comb" } ] ### Output ### ID 7
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "doxorubicin", "cyclophosphamide" ], "relation": "non_comb" } ] ### Output ### ID 8
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "amitriptyline", "nortriptyline" ], "relation": "non_comb" } ] ### Output ### ID 9
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "docetaxel", "paclitaxel" ], "relation": "non_comb" } ] ### Output ### ID 10
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "alisertib", "abiraterone" ], "relation": "COMB" } ] ### Output ### ID 11
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Tanespimycin", "trastuzumab" ], "relation": "POS" } ] ### Output ### ID 12
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "chloroquine", "proguanil" ], "relation": "COMB" } ] ### Output ### ID 13
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "phenytoin", "methylprednisolone" ], "relation": "POS" } ] ### Output ### ID 14
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Artesunate", "Dihydroartemisinin" ], "relation": "non_comb" } ] ### Output ### ID 15
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "bortezomib", "gemcitabine" ], "relation": "POS" } ] ### Output ### ID 16
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "afatinib", "bevacizumab" ], "relation": "POS" } ] ### Output ### ID 17
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "enzalutamide", "abiraterone" ], "relation": "POS" }, { "entities": [ "docetaxel", "abiraterone" ], "relation": "POS" } ] ### Output ### ID 18
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "prednisone", "cyclophosphamide" ], "relation": "POS" } ] ### Output ### ID 19
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cediranib", "gefitinib" ], "relation": "POS" } ] ### Output ### ID 20
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Chloroquine", "Hydroxychloroquine", "Remdesivir" ], "relation": "non_comb" } ] ### Output ### ID 21
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "bevacizumab", "ranibizumab" ], "relation": "non_comb" } ] ### Output ### ID 22
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "streptomycin", "penicillin" ], "relation": "POS" }, { "entities": [ "amikacin", "penicillin" ], "relation": "POS" } ] ### Output ### ID 23
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cyclophosphamide", "vincristine", "dacarbazine" ], "relation": "POS" } ] ### Output ### ID 24
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "ciprofloxacin", "ceftazidime", "ampicillin" ], "relation": "non_comb" } ] ### Output ### ID 25
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Paclitaxel", "docetaxel" ], "relation": "non_comb" } ] ### Output ### ID 26
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "vinblastine", "bleomycin" ], "relation": "POS" } ] ### Output ### ID 27
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "vincristine", "cyclophosphamide", "5-fluoro-uracil" ], "relation": "POS" } ] ### Output ### ID 28
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "estramustine", "etoposide" ], "relation": "POS" } ] ### Output ### ID 29
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "bendamustine", "ofatumumab" ], "relation": "POS" } ] ### Output ### ID 30
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "gemcitabine", "oxaliplatin" ], "relation": "POS" } ] ### Output ### ID 31
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rituximab", "intravenous immunoglobulin" ], "relation": "NEG" }, { "entities": [ "rituximab", "bortezomib" ], "relation": "NEG" } ] ### Output ### ID 32
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "methylprednisolone", "cyclosporine", "azathioprine" ], "relation": "POS" } ] ### Output ### ID 33
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cyclophosphamide", "vincristine", "prednisone" ], "relation": "COMB" }, { "entities": [ "fludarabine", "mitoxantrone" ], "relation": "COMB" } ] ### Output ### ID 34
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "gemcitabine", "paclitaxel", "capecitabine" ], "relation": "POS" } ] ### Output ### ID 35
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "voriconazole", "amphotericin", "B." ], "relation": "COMB" } ] ### Output ### ID 36
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Aspirin", "Cilostazol" ], "relation": "POS" } ] ### Output ### ID 37
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Gemcitabine", "vinorelbine" ], "relation": "POS" } ] ### Output ### ID 38
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "tenofovir disoproxil fumarate", "emtricitabine" ], "relation": "POS" } ] ### Output ### ID 39
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "tamoxifen", "exemestane", "anastrozole" ], "relation": "non_comb" } ] ### Output ### ID 40
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rosiglitazone", "glimepiride" ], "relation": "non_comb" } ] ### Output ### ID 41
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "doxorubicin", "cyclophosphamide", "paclitaxel" ], "relation": "POS" } ] ### Output ### ID 42
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cisplatin", "paclitaxel" ], "relation": "POS" }, { "entities": [ "cisplatin", "cyclophosphamide" ], "relation": "COMB" } ] ### Output ### ID 43
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "ezetimibe", "simvastatin" ], "relation": "POS" } ] ### Output ### ID 44
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "pseudoephedrine", "methamphetamine", "methamphetamine" ], "relation": "non_comb" } ] ### Output ### ID 45
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "procarbazine", "lomustine", "vincristine", "radiotherapy" ], "relation": "POS" } ] ### Output ### ID 46
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "vinorelbine", "gemcitabine" ], "relation": "POS" } ] ### Output ### ID 47
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "gentamicin", "penicillins" ], "relation": "POS" }, { "entities": [ "Tobramycin", "penicillins" ], "relation": "COMB" } ] ### Output ### ID 48
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "entecavir", "telbivudine" ], "relation": "non_comb" } ] ### Output ### ID 49
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "ixabepilone", "paclitaxel", "capecitabine", "vinorelbine", "pemetrexed", "irinotecan" ], "relation": "non_comb" } ] ### Output ### ID 50
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "fluticasone", "formoterol" ], "relation": "POS" } ] ### Output ### ID 51
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "anastrozole", "tamoxifen" ], "relation": "non_comb" } ] ### Output ### ID 52
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "tocilizumab", "tofacitinib" ], "relation": "non_comb" } ] ### Output ### ID 53
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Paclitaxel", "fulvestrant" ], "relation": "POS" } ] ### Output ### ID 54
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "ritodrine", "lidocaine", "ephedrine" ], "relation": "POS" }, { "entities": [ "ritodrine", "lidocaine", "phenylephrine" ], "relation": "COMB" } ] ### Output ### ID 55
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "busulfan", "cyclophosphamide" ], "relation": "POS" } ] ### Output ### ID 56
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "cyclosporine", "prednisone" ], "relation": "POS" } ] ### Output ### ID 57
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Tadalafil", "sildenafil" ], "relation": "non_comb" } ] ### Output ### ID 58
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "heparin", "enoxaparin" ], "relation": "non_comb" } ] ### Output ### ID 59
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "leucovorin", "5-FU" ], "relation": "POS" }, { "entities": [ "levamisole", "5-FU" ], "relation": "POS" } ] ### Output ### ID 60
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "tamoxifen", "letrozole" ], "relation": "non_comb" } ] ### Output ### ID 61
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "sorafenib", "flavopiridol" ], "relation": "POS" } ] ### Output ### ID 62
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "sorafenib", "curcumin" ], "relation": "POS" } ] ### Output ### ID 63
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "closantel", "albendazole" ], "relation": "POS" } ] ### Output ### ID 64
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "lidocaine", "tetracaine" ], "relation": "non_comb" } ] ### Output ### ID 65
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "bevacizumab", "irinotecan" ], "relation": "POS" } ] ### Output ### ID 66
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "nivolumab", "pembrolizumab" ], "relation": "non_comb" } ] ### Output ### ID 67
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rapamycin", "paclitaxel" ], "relation": "POS" } ] ### Output ### ID 68
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "atezolizumab", "bevacizumab" ], "relation": "POS" } ] ### Output ### ID 69
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "tamoxifen", "letrozole" ], "relation": "POS" } ] ### Output ### ID 70
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "nilotinib", "ponatinib" ], "relation": "non_comb" } ] ### Output ### ID 71
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "somatostatin", "everolimus" ], "relation": "POS" } ] ### Output ### ID 72
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "trastuzumab", "paclitaxel" ], "relation": "POS" } ] ### Output ### ID 73
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "basiliximab", "cyclosporine" ], "relation": "non_comb" } ] ### Output ### ID 74
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "posaconazole", "voriconazole" ], "relation": "NEG" } ] ### Output ### ID 75
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "paclitaxel", "capecitabine" ], "relation": "COMB" } ] ### Output ### ID 76
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "fluorouracil", "leucovorin" ], "relation": "POS" } ] ### Output ### ID 77
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "propranolol", "phenylephrine" ], "relation": "non_comb" } ] ### Output ### ID 78
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "paclitaxel", "vinorelbine" ], "relation": "POS" } ] ### Output ### ID 79
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "decitabine", "valproic" ], "relation": "NEG" } ] ### Output ### ID 80
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "clopidogrel", "aspirin", "clopidogrel" ], "relation": "non_comb" } ] ### Output ### ID 81
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "docetaxel", "irinotecan" ], "relation": "NEG" } ] ### Output ### ID 82
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "paclitaxel", "carboplatin" ], "relation": "POS" } ] ### Output ### ID 83
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "oxaliplatin", "docetaxel" ], "relation": "non_comb" } ] ### Output ### ID 84
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "luspatercept", "venetoclax" ], "relation": "non_comb" } ] ### Output ### ID 85
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "enalapril", "captopril" ], "relation": "non_comb" } ] ### Output ### ID 86
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "imipenem", "imipenem", "amphotericin" ], "relation": "non_comb" } ] ### Output ### ID 87
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rituximab", "cyclophosphamide", "doxorubicin", "vincristine", "prednisolone" ], "relation": "POS" } ] ### Output ### ID 88
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rituximab", "vincristine", "cyclophosphamide" ], "relation": "POS" } ] ### Output ### ID 89
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "lamotrigine", "carbamazepine" ], "relation": "non_comb" } ] ### Output ### ID 90
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "decitabine", "carboplatin" ], "relation": "COMB" } ] ### Output ### ID 91
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "vinblastine", "bleomycin", "cis-platinum" ], "relation": "POS" } ] ### Output ### ID 92
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "atenolol", "metoprolol", "acebutolol", "oxprenolol", "nadolol", "timolol" ], "relation": "POS" } ] ### Output ### ID 93
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "raloxifene", "nimesulide" ], "relation": "POS" } ] ### Output ### ID 94
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "dolutegravir", "tenofovir" ], "relation": "non_comb" } ] ### Output ### ID 95
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Abiraterone", "prednisone" ], "relation": "POS" } ] ### Output ### ID 96
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "Nivolumab", "ipilimumab" ], "relation": "POS" } ] ### Output ### ID 97
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "rapamycin", "topotecan" ], "relation": "POS" } ] ### Output ### ID 98
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "PNU-159548", "doxorubicin", "methotrexate", "cisplatin" ], "relation": "non_comb" } ] ### Output ### ID 99
### Instruction The following content involves pharmaceutical entities and the different types of relationships between them. 'POS' indicates that drugs are used in combination and have positive effects. 'NEG' represents that the combined use of drugs leads to adverse reactions or counteractive effects. 'COMB' means that drugs are used together, but their interaction and effects are not yet clear. Finally, 'non_comb' signifies that there is no combination usage between the drugs. ### Input [ { "entities": [ "human tumor necrosis factor", "Etoposide" ], "relation": "POS" }, { "entities": [ "human tumor necrosis factor", "Doxorubicin" ], "relation": "POS" } ] ### Output ### ID 100