Upload boltz_repaired_d70_input_sequences.json with huggingface_hub
Browse files
boltz_repaired_d70_input_sequences.json
ADDED
|
@@ -0,0 +1,34 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
{
|
| 2 |
+
"chain_A_full_LC": "DIQMTQSPSSLSASVGDRVTITCRASQDVQTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC",
|
| 3 |
+
"chain_B_full_HC": "EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGFTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP",
|
| 4 |
+
"chain_C_HER2_ECD": "TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLSPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTATQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDSNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSIWKFPDEEGACQPCPIN",
|
| 5 |
+
"mutations_vs_wt": [
|
| 6 |
+
[
|
| 7 |
+
"A",
|
| 8 |
+
30,
|
| 9 |
+
"N",
|
| 10 |
+
"Q"
|
| 11 |
+
],
|
| 12 |
+
[
|
| 13 |
+
"B",
|
| 14 |
+
57,
|
| 15 |
+
"Y",
|
| 16 |
+
"F"
|
| 17 |
+
]
|
| 18 |
+
],
|
| 19 |
+
"mutations_vs_d70": [
|
| 20 |
+
[
|
| 21 |
+
"A",
|
| 22 |
+
30,
|
| 23 |
+
"G",
|
| 24 |
+
"Q"
|
| 25 |
+
],
|
| 26 |
+
[
|
| 27 |
+
"B",
|
| 28 |
+
57,
|
| 29 |
+
"A",
|
| 30 |
+
"F"
|
| 31 |
+
]
|
| 32 |
+
],
|
| 33 |
+
"source": "WT full Fab with variable-domain repair mutations applied"
|
| 34 |
+
}
|