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DeepVRegulome

Text Classification
Transformers
biology
genomics
dna
variant-effect-prediction
dnabert
deepvregulome
transcription-factors
histone-modifications
ENCODE
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+ ---
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+ license: cc-by-nc-4.0
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+ tags:
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+ - biology
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+ - genomics
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+ - dna
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+ - variant-effect-prediction
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+ - dnabert
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+ - deepvregulome
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+ - transcription-factors
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+ - histone-modifications
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+ - ENCODE
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+ datasets:
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+ - ENCODE
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+ library_name: transformers
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+ pipeline_tag: text-classification
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+ ---
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+
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+ # DeepVRegulome
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+
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+ **462 fine-tuned DNABERT models for regulatory variant effect prediction**
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+
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+ DeepVRegulome is an end-to-end framework for predicting the functional impact
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+ of small somatic variants in non-coding regulatory regions using fine-tuned
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+ [DNABERT](https://github.com/jerryji1993/DNABERT) models. It covers **458
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+ transcription factors** and **4 histone modifications** from ENCODE ChIP-seq data.
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+
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+ 📄 **Paper:** [arXiv:2511.09026](https://arxiv.org/abs/2511.09026)
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+ 💻 **Code:** [GitHub](https://github.com/DavuluriLab/DeepVRegulome)
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+ 🌐 **Web App:** [deepvregulome.streamlit.app](https://deepvregulome.streamlit.app)
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+
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+ ## Quick Start
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+
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+ ```python
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+ from transformers import AutoModelForSequenceClassification, AutoTokenizer
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+ import torch
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+
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+ # Load any model using subfolder
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+ model_name = "CTCFL" # or "SP1", "MYC", "H3K27ac", etc.
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+ tokenizer = AutoTokenizer.from_pretrained(
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+ "duttaprat/DeepVRegulome", subfolder=f"models/{model_name}"
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+ )
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+ model = AutoModelForSequenceClassification.from_pretrained(
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+ "duttaprat/DeepVRegulome", subfolder=f"models/{model_name}"
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+ )
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+ model.eval()
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+
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+ # Convert DNA to 6-mer representation
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+ def to_kmer(seq, k=6):
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+ return " ".join([seq[i:i+k] for i in range(len(seq) - k + 1)])
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+
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+ # Predict binding probability
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+ sequence = "ATCGATCG..." # 301bp DNA sequence
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+ inputs = tokenizer(to_kmer(sequence), return_tensors="pt",
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+ max_length=512, truncation=True, padding=True)
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+ with torch.no_grad():
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+ prob = torch.softmax(model(**inputs).logits, dim=-1)[0][1].item()
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+ print(f"{model_name} binding probability: {prob:.4f}")
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+ ```
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+
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+ ## Variant Effect Scoring
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+
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+ ```python
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+ import math
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+
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+ def score_variant(model, tokenizer, ref_seq, alt_seq):
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+ probs = {}
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+ for name, seq in [("REF", ref_seq), ("ALT", alt_seq)]:
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+ inputs = tokenizer(to_kmer(seq), return_tensors="pt",
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+ max_length=512, truncation=True, padding=True)
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+ with torch.no_grad():
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+ probs[name] = torch.softmax(model(**inputs).logits, dim=-1)[0][1].item()
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+
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+ eps = 1e-7
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+ lo_ref = math.log((probs["REF"] + eps) / (1 - probs["REF"] + eps))
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+ lo_alt = math.log((probs["ALT"] + eps) / (1 - probs["ALT"] + eps))
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+ return {
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+ "prob_ref": probs["REF"],
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+ "prob_alt": probs["ALT"],
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+ "log_odds_change": lo_alt - lo_ref,
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+ "disrupted": abs(lo_alt - lo_ref) > 2.0,
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+ }
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+ ```
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+
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+ ## Available Models (462)
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+
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+ Each model is in `models/<NAME>/` subfolder. Load with:
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+ ```python
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+ AutoModel.from_pretrained("duttaprat/DeepVRegulome", subfolder="models/<NAME>")
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+ ```
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+
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+ | # | Model | Type | Accuracy | F1 | ROC-AUC | PR-AUC | Peaks |
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+ |---|-------|------|----------|-----|---------|--------|-------|
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+ | 1 | `CTCFL` | TF | 98.39 | 98.4 | 99.71 | 99.7 | 12743 |
95
+ | 2 | `ZNF426` | TF | 97.09 | 96.64 | 98.08 | 98.65 | 7915 |
96
+ | 3 | `SAFB` | TF | 97.02 | 96.81 | 98.38 | 98.57 | 5361 |
97
+ | 4 | `RBM34` | TF | 97 | 96.53 | 98.18 | 98.44 | 928 |
98
+ | 5 | `TAF15` | TF | 96.74 | 96.41 | 99.02 | 98.58 | 17900 |
99
+ | 6 | `PCBP1` | TF | 96.7 | 95.94 | 99.19 | 98.66 | 16229 |
100
+ | 7 | `SRSF3` | TF | 96.6 | 96.52 | 98.2 | 95.53 | 1610 |
101
+ | 8 | `RBM14` | TF | 96.57 | 95.73 | 98.8 | 98.4 | 2463 |
102
+ | 9 | `KDM4A` | TF | 96.07 | 95.99 | 99.08 | 98.72 | 25968 |
103
+ | 10 | `NFYA` | TF | 95.91 | 95.19 | 96.88 | 93.73 | 4313 |
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+ | 11 | `SPI1` | TF | 95.79 | 95.78 | 98.75 | 98.38 | 104150 |
105
+ | 12 | `HLF` | TF | 95.71 | 95.83 | 98.88 | 98.74 | 66792 |
106
+ | 13 | `EGR2` | TF | 95.68 | 99.22 | 99.75 | 99.6 | 57610 |
107
+ | 14 | `HNRNPLL` | TF | 95.43 | 93.73 | 98.77 | 97.88 | 25270 |
108
+ | 15 | `HNRNPK` | TF | 95.41 | 94.27 | 97.05 | 96.06 | 24014 |
109
+ | 16 | `FIP1L1` | TF | 95.35 | 94.16 | 98.25 | 98.13 | 10123 |
110
+ | 17 | `ZNF654` | TF | 95.31 | 95.28 | 97.93 | 98.17 | 33357 |
111
+ | 18 | `ZNF146` | TF | 95.23 | 94.66 | 97.57 | 97.69 | 38167 |
112
+ | 19 | `E2F6` | TF | 95.14 | 93.71 | 98.25 | 96.91 | 30723 |
113
+ | 20 | `C11orf30` | TF | 95.13 | 94.98 | 98.63 | 98.61 | 58686 |
114
+ | 21 | `FUS` | TF | 95.03 | 93.76 | 94.87 | 93.76 | 7495 |
115
+ | 22 | `USF1` | TF | 94.95 | 94.93 | 98.05 | 97.78 | 60863 |
116
+ | 23 | `ZNF770` | TF | 94.91 | 95.01 | 98.04 | 97.28 | 57572 |
117
+ | 24 | `AGO1` | TF | 94.81 | 92.98 | 97.19 | 96.16 | 16201 |
118
+ | 25 | `MAFG` | TF | 94.74 | 94.7 | 97.91 | 97.78 | 44030 |
119
+ | 26 | `ZFHX2` | TF | 94.73 | 99.21 | 99.82 | 99.74 | 61052 |
120
+ | 27 | `THAP1` | TF | 94.7 | 94.48 | 98.22 | 97.82 | 5210 |
121
+ | 28 | `HES2` | TF | 94.55 | 84.34 | 97.15 | 84.39 | 6520 |
122
+ | 29 | `SRSF1` | TF | 94.49 | 93.59 | 98.34 | 97.9 | 9933 |
123
+ | 30 | `NFE2` | TF | 94.22 | 99.19 | 99.76 | 99.72 | 53717 |
124
+ | 31 | `MITF` | TF | 94.14 | 93.57 | 98.35 | 98.12 | 36171 |
125
+ | 32 | `MAFF` | TF | 93.91 | 93.91 | 97.86 | 97.17 | 65684 |
126
+ | 33 | `PCBP2` | TF | 93.89 | 93.23 | 96.53 | 96.61 | 5328 |
127
+ | 34 | `ZIC2` | TF | 93.77 | 93.9 | 97.82 | 96.94 | 56766 |
128
+ | 35 | `GLIS2` | TF | 93.74 | 93.14 | 98.22 | 97.8 | 33566 |
129
+ | 36 | `ZNF121` | TF | 93.64 | 98.86 | 99.34 | 99.26 | 35805 |
130
+ | 37 | `SP2` | TF | 93.6 | 93.13 | 96.81 | 95.36 | 27956 |
131
+ | 38 | `SCRT2` | TF | 93.59 | 98.97 | 99.56 | 99.17 | 59462 |
132
+ | 39 | `BATF` | TF | 93.58 | 93.82 | 98.16 | 97.93 | 36658 |
133
+ | 40 | `HNRNPL` | TF | 93.57 | 92.29 | 97.59 | 96.88 | 24447 |
134
+ | 41 | `NFE2L2` | TF | 93.53 | 91.27 | 97.24 | 96.09 | 26392 |
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+ | 42 | `ZNF585B` | TF | 93.43 | 93.4 | 97.78 | 98 | 7381 |
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+ | 43 | `NFYB` | TF | 93.31 | 91.7 | 96.3 | 95.22 | 14696 |
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+ | 44 | `ZSCAN4` | TF | 93.25 | 92.72 | 97.64 | 97.75 | 23997 |
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+ | 45 | `ZNF316` | TF | 93.22 | 93.43 | 97.42 | 97.55 | 97518 |
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+ | 46 | `ZNF140` | TF | 93.19 | 92.79 | 96.45 | 96.93 | 7623 |
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+ | 47 | `ZNF777` | TF | 93.12 | 92.58 | 97.24 | 97.07 | 7181 |
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+ | 48 | `CBFA2T2` | TF | 93.06 | 93.09 | 97.31 | 97.25 | 32239 |
142
+ | 49 | `TFAP4` | TF | 93 | 92.84 | 96.79 | 94.97 | 27035 |
143
+ | 50 | `ATF4` | TF | 93 | 92.84 | 97.72 | 97.64 | 39441 |
144
+ | 51 | `CTBP2` | TF | 92.98 | 92.36 | 96.78 | 94.11 | 7351 |
145
+ | 52 | `MXD3` | TF | 92.88 | 92.08 | 98.24 | 97.87 | 14677 |
146
+ | 53 | `E2F1` | TF | 92.88 | 86.4 | 95.25 | 91.61 | 18927 |
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+ | 54 | `ZNF202` | TF | 92.87 | 92.87 | 96.29 | 96.5 | 6476 |
148
+ | 55 | `ZNF266` | TF | 92.84 | 92.56 | 96.93 | 96.93 | 5097 |
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+ | 56 | `ZNF263` | TF | 92.83 | 91.44 | 97.39 | 96.16 | 35011 |
150
+ | 57 | `ZNF433` | TF | 92.77 | 92.49 | 96.97 | 97.7 | 3530 |
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+ | 58 | `RBM39` | TF | 92.73 | 91.61 | 97.44 | 96.77 | 29478 |
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+ | 59 | `ZNF680` | TF | 92.69 | 92.24 | 97.36 | 97.68 | 10483 |
153
+ | 60 | `ZNF341` | TF | 92.66 | 92.24 | 97.24 | 96.26 | 33413 |
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+ | 61 | `E2F4` | TF | 92.64 | 90.76 | 97.32 | 97.07 | 11270 |
155
+ | 62 | `CBFA2T3` | TF | 92.59 | 92.67 | 96.97 | 96.03 | 51994 |
156
+ | 63 | `ZNF555` | TF | 92.57 | 92.23 | 94.78 | 96.56 | 6664 |
157
+ | 64 | `RBM25` | TF | 92.56 | 92.48 | 96.96 | 97.05 | 47193 |
158
+ | 65 | `MAFK` | TF | 92.55 | 92.65 | 97.36 | 97.6 | 121216 |
159
+ | 66 | `ZNF623` | TF | 92.53 | 92.19 | 96.77 | 97.51 | 14353 |
160
+ | 67 | `KAT2A` | TF | 92.45 | 91.3 | 92.39 | 92.84 | 171 |
161
+ | 68 | `SIN3B` | TF | 92.45 | 90.29 | 97.21 | 96.89 | 11700 |
162
+ | 69 | `CEBPA` | TF | 92.39 | 98.89 | 99.7 | 99.6 | 57842 |
163
+ | 70 | `U2AF2` | TF | 92.37 | 91.72 | 96.2 | 94.8 | 2777 |
164
+ | 71 | `ZBTB10` | TF | 92.27 | 91.31 | 96.02 | 94.41 | 15441 |
165
+ | 72 | `PBX3` | TF | 92.25 | 92.23 | 96.51 | 95.35 | 12981 |
166
+ | 73 | `SAP30` | TF | 92.08 | 90.13 | 96.21 | 92.3 | 15727 |
167
+ | 74 | `PHF8` | TF | 92.03 | 88.66 | 96.25 | 95.67 | 30275 |
168
+ | 75 | `PAX5` | TF | 92.02 | 90.77 | 96.81 | 94.42 | 36090 |
169
+ | 76 | `ZNF785` | TF | 92.01 | 91.35 | 97.35 | 97.16 | 6605 |
170
+ | 77 | `ZNF76` | TF | 92 | 90.95 | 93.83 | 89.14 | 11676 |
171
+ | 78 | `HNF4G` | TF | 91.93 | 90.87 | 96.43 | 95.82 | 35204 |
172
+ | 79 | `AHR` | TF | 91.82 | 91.39 | 97.21 | 96.43 | 10611 |
173
+ | 80 | `ZC3H11A` | TF | 91.8 | 91.33 | 96.31 | 97.12 | 9905 |
174
+ | 81 | `RFX1` | TF | 91.79 | 90.4 | 96.44 | 96.43 | 38873 |
175
+ | 82 | `SMAD4` | TF | 91.75 | 91.7 | 96.19 | 94.92 | 43342 |
176
+ | 83 | `UBTF` | TF | 91.73 | 89.06 | 94.72 | 91.45 | 19173 |
177
+ | 84 | `ZNF704` | TF | 91.71 | 90.84 | 94.66 | 94.52 | 1834 |
178
+ | 85 | `TAL1` | TF | 91.69 | 90.15 | 96.07 | 95.03 | 36574 |
179
+ | 86 | `ZBTB7A` | TF | 91.69 | 90.22 | 97.14 | 95.99 | 37497 |
180
+ | 87 | `CEBPB` | TF | 91.69 | 98.47 | 99.54 | 99.42 | 148540 |
181
+ | 88 | `NFIL3` | TF | 91.67 | 91.52 | 96.42 | 96 | 38852 |
182
+ | 89 | `XRCC5` | TF | 91.61 | 90.04 | 95.9 | 93.22 | 32847 |
183
+ | 90 | `U2AF1` | TF | 91.6 | 89.92 | 96.08 | 96 | 8379 |
184
+ | 91 | `ZNF34` | TF | 91.58 | 91.34 | 95.28 | 96.71 | 9650 |
185
+ | 92 | `FOXP2` | TF | 91.57 | 90.78 | 96.14 | 93.84 | 24150 |
186
+ | 93 | `AGO2` | TF | 91.55 | 89.26 | 95.16 | 94.66 | 33079 |
187
+ | 94 | `RUNX3` | TF | 91.53 | 98.64 | 99.5 | 99.27 | 69903 |
188
+ | 95 | `ZBED5` | TF | 91.49 | 91.43 | 97.14 | 96.94 | 5100 |
189
+ | 96 | `RARA` | TF | 91.46 | 91.59 | 95.97 | 94.89 | 42489 |
190
+ | 97 | `FOS` | TF | 91.45 | 98.69 | 99.62 | 99.63 | 169317 |
191
+ | 98 | `SP3` | TF | 91.44 | 90.22 | 95.27 | 94.77 | 23619 |
192
+ | 99 | `NANOG` | TF | 91.43 | 90.45 | 95.72 | 94.36 | 15681 |
193
+ | 100 | `USF2` | TF | 91.39 | 89.66 | 96.88 | 96.27 | 37240 |
194
+ | 101 | `SP5` | TF | 91.37 | 91.12 | 95.54 | 94.28 | 23155 |
195
+ | 102 | `HNF4A` | TF | 91.37 | 91.63 | 96.12 | 95.11 | 89892 |
196
+ | 103 | `ZNF354C` | TF | 91.37 | 90.59 | 95.08 | 96.39 | 1640 |
197
+ | 104 | `ZNF444` | TF | 91.35 | 90.8 | 95.64 | 94.38 | 25366 |
198
+ | 105 | `GMEB2` | TF | 91.33 | 90.21 | 95.76 | 95.89 | 4800 |
199
+ | 106 | `ZNF677` | TF | 91.33 | 91.35 | 94.68 | 94.52 | 5777 |
200
+ | 107 | `IRF4` | TF | 91.18 | 91.14 | 96.12 | 95.26 | 21810 |
201
+ | 108 | `ETV5` | TF | 91.18 | 90.89 | 96.55 | 95.11 | 29604 |
202
+ | 109 | `PRPF4` | TF | 91.14 | 89.78 | 96.21 | 95.93 | 8605 |
203
+ | 110 | `FOXA3` | TF | 91.12 | 91.46 | 96.8 | 96.6 | 45297 |
204
+ | 111 | `ZNF292` | TF | 91.11 | 90.59 | 94.63 | 96.11 | 1900 |
205
+ | 112 | `GLIS1` | TF | 91.07 | 90.1 | 96.04 | 95.32 | 58506 |
206
+ | 113 | `FOXA2` | TF | 91.05 | 91.28 | 96.39 | 96.06 | 99343 |
207
+ | 114 | `KLF9` | TF | 90.99 | 87.95 | 95.59 | 94.68 | 32290 |
208
+ | 115 | `SOX5` | TF | 90.98 | 90.85 | 95.23 | 93.77 | 37979 |
209
+ | 116 | `BCL6` | TF | 90.97 | 90.9 | 96.3 | 95.48 | 38142 |
210
+ | 117 | `IRF3` | TF | 90.97 | 87.65 | 96.01 | 95.01 | 5726 |
211
+ | 118 | `ZNF223` | TF | 90.97 | 90.6 | 95.52 | 95.63 | 5176 |
212
+ | 119 | `HCFC1` | TF | 90.96 | 85.32 | 94.4 | 91.32 | 19700 |
213
+ | 120 | `HNRNPH1` | TF | 90.85 | 89.75 | 96.02 | 95.65 | 2446 |
214
+ | 121 | `DEAF1` | TF | 90.85 | 90.18 | 94.68 | 95.53 | 3170 |
215
+ | 122 | `CEBPZ` | TF | 90.82 | 86.79 | 89.86 | 85.64 | 1971 |
216
+ | 123 | `PTBP1` | TF | 90.8 | 89.88 | 94.48 | 89.35 | 8063 |
217
+ | 124 | `STAT3` | TF | 90.79 | 90.81 | 96.82 | 96.85 | 65231 |
218
+ | 125 | `KAT2B` | TF | 90.77 | 90.48 | 96.6 | 96.8 | 3106 |
219
+ | 126 | `SOX13` | TF | 90.76 | 90.83 | 96.32 | 95.69 | 48796 |
220
+ | 127 | `ZNF423` | TF | 90.75 | 90.32 | 94.63 | 93.05 | 11299 |
221
+ | 128 | `STAT2` | TF | 90.73 | 89.46 | 95.84 | 93.72 | 4303 |
222
+ | 129 | `MEIS2` | TF | 90.71 | 90.78 | 96.27 | 96.07 | 52199 |
223
+ | 130 | `ATF2` | TF | 90.69 | 90.57 | 94.77 | 94.25 | 110897 |
224
+ | 131 | `NFIA` | TF | 90.67 | 90.58 | 95.6 | 95.07 | 27816 |
225
+ | 132 | `PATZ1` | TF | 90.67 | 89.53 | 96.62 | 95.93 | 35416 |
226
+ | 133 | `ZNF398` | TF | 90.66 | 89.94 | 94.96 | 92.96 | 26224 |
227
+ | 134 | `KLF1` | TF | 90.65 | 89.32 | 94.52 | 92.79 | 40024 |
228
+ | 135 | `SCRT1` | TF | 90.65 | 90.42 | 94.93 | 94.54 | 25487 |
229
+ | 136 | `NFIB` | TF | 90.65 | 87.93 | 96.05 | 95.1 | 27982 |
230
+ | 137 | `PLRG1` | TF | 90.64 | 90.06 | 96.68 | 96.85 | 2256 |
231
+ | 138 | `PRDM1` | TF | 90.62 | 95.17 | 98.83 | 98.73 | 50489 |
232
+ | 139 | `ZNF133` | TF | 90.61 | 90.22 | 95.36 | 94.71 | 8423 |
233
+ | 140 | `SREBF2` | TF | 90.59 | 89.11 | 96.2 | 95.55 | 4933 |
234
+ | 141 | `EBF1` | TF | 90.59 | 90.64 | 95.31 | 94.3 | 56947 |
235
+ | 142 | `THAP11` | TF | 90.57 | 89.79 | 94.85 | 93.4 | 31698 |
236
+ | 143 | `ZNF48` | TF | 90.56 | 89.58 | 94.31 | 91 | 28840 |
237
+ | 144 | `POU5F1` | TF | 90.56 | 89.71 | 96.35 | 95.35 | 7870 |
238
+ | 145 | `RB1` | TF | 90.5 | 87.95 | 94 | 91.78 | 31314 |
239
+ | 146 | `ZBTB6` | TF | 90.44 | 90.06 | 95.43 | 95.01 | 13955 |
240
+ | 147 | `HNF1A` | TF | 90.44 | 90.13 | 93.47 | 91.12 | 12818 |
241
+ | 148 | `KDM5B` | TF | 90.43 | 88.75 | 96.53 | 95.91 | 18356 |
242
+ | 149 | `ZNF521` | TF | 90.37 | 90.04 | 96.17 | 96.82 | 1585 |
243
+ | 150 | `GLI4` | TF | 90.37 | 90.04 | 96.45 | 96.57 | 6130 |
244
+ | 151 | `RERE` | TF | 90.37 | 89.28 | 95.15 | 93.11 | 11849 |
245
+ | 152 | `ZBTB26` | TF | 90.33 | 87.38 | 93.76 | 90.92 | 32837 |
246
+ | 153 | `FOXP1` | TF | 90.33 | 89.44 | 95.14 | 93.99 | 31380 |
247
+ | 154 | `ZNF596` | TF | 90.31 | 89.88 | 95.56 | 95.65 | 14087 |
248
+ | 155 | `ZBTB21` | TF | 90.29 | 89.52 | 96.14 | 95.86 | 18547 |
249
+ | 156 | `HMGXB4` | TF | 90.27 | 89.5 | 93.94 | 91.67 | 25984 |
250
+ | 157 | `TEAD1` | TF | 90.27 | 90.29 | 95.53 | 94.84 | 33326 |
251
+ | 158 | `ZNF660` | TF | 90.18 | 89.77 | 94.75 | 94.22 | 29821 |
252
+ | 159 | `SFPQ` | TF | 90.18 | 90.09 | 91.7 | 90.66 | 335 |
253
+ | 160 | `ZNF658` | TF | 90.14 | 88.6 | 93.92 | 94.54 | 1325 |
254
+ | 161 | `SKI` | TF | 90.12 | 89.27 | 95.47 | 93.65 | 30460 |
255
+ | 162 | `SRF` | TF | 90.12 | 87.92 | 96 | 94.95 | 27692 |
256
+ | 163 | `CEBPG` | TF | 90.11 | 90.14 | 96.25 | 96.42 | 87912 |
257
+ | 164 | `ZHX1` | TF | 90.1 | 88.61 | 94.55 | 92.57 | 5512 |
258
+ | 165 | `RUNX1` | TF | 90.07 | 89.3 | 94.29 | 91.85 | 7554 |
259
+ | 166 | `RXRB` | TF | 90.07 | 89.83 | 94.62 | 92.92 | 38236 |
260
+ | 167 | `ZBTB48` | TF | 90.05 | 89.29 | 96.26 | 95.22 | 24899 |
261
+ | 168 | `ZNF747` | TF | 90.02 | 88.84 | 95.87 | 95.94 | 1427 |
262
+ | 169 | `VEZF1` | TF | 90.01 | 88.14 | 94.32 | 93.48 | 35726 |
263
+ | 170 | `GATA1` | TF | 89.96 | 87.31 | 93.39 | 91.08 | 33326 |
264
+ | 171 | `ZNF670` | TF | 89.95 | 88.3 | 95.12 | 95.63 | 1288 |
265
+ | 172 | `ARID4B` | TF | 89.94 | 88.99 | 94.05 | 92.27 | 42648 |
266
+ | 173 | `ZNF449` | TF | 89.94 | 89.32 | 94.61 | 94.5 | 18374 |
267
+ | 174 | `KLF17` | TF | 89.93 | 89.05 | 96.18 | 95.48 | 25375 |
268
+ | 175 | `ZBTB20` | TF | 89.91 | 88.23 | 95.2 | 92.94 | 31889 |
269
+ | 176 | `ELF3` | TF | 89.85 | 89.43 | 95.06 | 93.86 | 35966 |
270
+ | 177 | `ZNF16` | TF | 89.85 | 89.14 | 95.41 | 95.27 | 2784 |
271
+ | 178 | `ZMIZ1` | TF | 89.85 | 90.09 | 95.22 | 95.28 | 1077 |
272
+ | 179 | `ZSCAN5A` | TF | 89.84 | 89.2 | 93.59 | 90.92 | 8202 |
273
+ | 180 | `ZNF143` | TF | 89.84 | 98.49 | 99.48 | 99.5 | 66295 |
274
+ | 181 | `ZNF513` | TF | 89.78 | 88.85 | 94.49 | 95.41 | 11211 |
275
+ | 182 | `PPARG` | TF | 89.77 | 89.47 | 94.59 | 93.53 | 23903 |
276
+ | 183 | `ZBTB8A` | TF | 89.73 | 88.24 | 94 | 92.72 | 32420 |
277
+ | 184 | `IRF5` | TF | 89.71 | 89.41 | 93.56 | 94.62 | 2755 |
278
+ | 185 | `ZMYM3` | TF | 89.71 | 89.32 | 95.52 | 95.45 | 43157 |
279
+ | 186 | `DEK` | TF | 89.7 | 88.82 | 95.38 | 93.29 | 8490 |
280
+ | 187 | `GABPB1` | TF | 89.7 | 89.12 | 94.29 | 92.92 | 47437 |
281
+ | 188 | `ZNF629` | TF | 89.69 | 88.91 | 94.14 | 92.43 | 37813 |
282
+ | 189 | `ETV1` | TF | 89.68 | 89.39 | 95.3 | 95.09 | 20672 |
283
+ | 190 | `ZNF394` | TF | 89.67 | 88.63 | 94.54 | 94.01 | 28297 |
284
+ | 191 | `TEAD4` | TF | 89.66 | 89.49 | 95.4 | 94.56 | 34189 |
285
+ | 192 | `PHF20` | TF | 89.63 | 88.59 | 94.4 | 91.57 | 13930 |
286
+ | 193 | `RBBP5` | TF | 89.59 | 85.4 | 96.01 | 94.46 | 30322 |
287
+ | 194 | `NFYC` | TF | 89.59 | 89.07 | 95.3 | 95.46 | 15080 |
288
+ | 195 | `ELK1` | TF | 89.58 | 84.66 | 91.33 | 89.55 | 12298 |
289
+ | 196 | `H4K12ac` | HISTONE | 89.57 | 89.53 | 96.1 | 95.46 | 42837 |
290
+ | 197 | `HMBOX1` | TF | 89.55 | 88.79 | 95.65 | 94.82 | 24883 |
291
+ | 198 | `KDM5A` | TF | 89.53 | 82.52 | 92.86 | 90.18 | 13023 |
292
+ | 199 | `WHSC1` | TF | 89.51 | 89.25 | 94.42 | 89.89 | 1801 |
293
+ | 200 | `ZNF692` | TF | 89.51 | 88.62 | 94.15 | 92.63 | 30183 |
294
+ | 201 | `MEF2B` | TF | 89.51 | 88.5 | 94.65 | 93.45 | 34822 |
295
+ | 202 | `TCF7L2` | TF | 89.46 | 86.81 | 94.06 | 91.99 | 28567 |
296
+ | 203 | `SAP130` | TF | 89.46 | 89.63 | 93.52 | 92.26 | 58021 |
297
+ | 204 | `SETDB1` | TF | 89.45 | 87.69 | 96.29 | 95.41 | 4903 |
298
+ | 205 | `ZKSCAN1` | TF | 89.45 | 87.61 | 94.37 | 92.44 | 20226 |
299
+ | 206 | `GATA4` | TF | 89.43 | 88.99 | 94.52 | 91.79 | 12156 |
300
+ | 207 | `EGR1` | TF | 89.43 | 89.26 | 93.84 | 93.58 | 67451 |
301
+ | 208 | `SUZ12` | TF | 89.36 | 82.88 | 94.21 | 91.33 | 24316 |
302
+ | 209 | `HDAC6` | TF | 89.35 | 87.38 | 95.07 | 94.75 | 5762 |
303
+ | 210 | `TEAD3` | TF | 89.35 | 89.2 | 95.32 | 93.94 | 42854 |
304
+ | 211 | `SRSF9` | TF | 89.34 | 87.07 | 96.1 | 95.7 | 846 |
305
+ | 212 | `MLX` | TF | 89.33 | 88.85 | 93.58 | 91.33 | 14640 |
306
+ | 213 | `ARID1B` | TF | 89.32 | 88.77 | 95.17 | 94.59 | 45992 |
307
+ | 214 | `ZSCAN30` | TF | 89.31 | 88.65 | 94.12 | 92.49 | 24704 |
308
+ | 215 | `ZFP36` | TF | 89.3 | 86.44 | 94.32 | 92.7 | 32993 |
309
+ | 216 | `ZFP64` | TF | 89.3 | 88.8 | 94.25 | 93.12 | 9433 |
310
+ | 217 | `ZNF518A` | TF | 89.3 | 88.1 | 94.68 | 95.04 | 16690 |
311
+ | 218 | `ZNF512` | TF | 89.29 | 87.52 | 95.55 | 95.6 | 17500 |
312
+ | 219 | `MEF2C` | TF | 89.25 | 89.19 | 94.66 | 93.88 | 11421 |
313
+ | 220 | `ARID2` | TF | 89.24 | 88.78 | 93.47 | 91.82 | 11585 |
314
+ | 221 | `IKZF5` | TF | 89.21 | 88.59 | 94.7 | 92.99 | 25386 |
315
+ | 222 | `PRDM2` | TF | 89.19 | 88.58 | 93.29 | 91.23 | 3824 |
316
+ | 223 | `KDM6A` | TF | 89.17 | 88.82 | 95.31 | 94.56 | 12193 |
317
+ | 224 | `RXRA` | TF | 89.17 | 89.44 | 94.78 | 93.82 | 85611 |
318
+ | 225 | `NRF1` | TF | 89.15 | 87.63 | 93.52 | 92.27 | 41391 |
319
+ | 226 | `MEF2A` | TF | 89.15 | 89.07 | 95.08 | 95.07 | 22725 |
320
+ | 227 | `SREBF1` | TF | 89.15 | 87.65 | 95.62 | 95.11 | 13518 |
321
+ | 228 | `BCOR` | TF | 89.08 | 88.74 | 95.34 | 94.44 | 41985 |
322
+ | 229 | `FOSL1` | TF | 89.06 | 88.05 | 94.11 | 93.96 | 43596 |
323
+ | 230 | `ZFP69B` | TF | 89.05 | 88.39 | 94.54 | 93.79 | 21782 |
324
+ | 231 | `ZNF837` | TF | 89 | 88.53 | 94.06 | 94.52 | 2332 |
325
+ | 232 | `CREB1` | TF | 88.96 | 89.04 | 95.48 | 96.05 | 89914 |
326
+ | 233 | `KDM3A` | TF | 88.94 | 88.07 | 92.68 | 88.4 | 15970 |
327
+ | 234 | `POU2F2` | TF | 88.92 | 88.77 | 93.25 | 89.71 | 19963 |
328
+ | 235 | `RBPJ` | TF | 88.92 | 87.6 | 94.85 | 93.61 | 24864 |
329
+ | 236 | `H2AK9ac` | HISTONE | 88.91 | 89.24 | 94.58 | 92.7 | 129243 |
330
+ | 237 | `IRF2` | TF | 88.9 | 87.49 | 93.77 | 92.14 | 31753 |
331
+ | 238 | `EED` | TF | 88.9 | 88.18 | 94.22 | 92.87 | 33175 |
332
+ | 239 | `CBFB` | TF | 88.89 | 87.72 | 93.81 | 91.26 | 18476 |
333
+ | 240 | `ZNF362` | TF | 88.88 | 87.44 | 94.25 | 92.46 | 20426 |
334
+ | 241 | `HMG20A` | TF | 88.87 | 88.31 | 94.68 | 93.45 | 24288 |
335
+ | 242 | `NR2F6` | TF | 88.87 | 88.87 | 93.72 | 92 | 59262 |
336
+ | 243 | `MIXL1` | TF | 88.8 | 88.4 | 94.17 | 93.38 | 25659 |
337
+ | 244 | `ZNF768` | TF | 88.79 | 88.37 | 92.77 | 94.22 | 7605 |
338
+ | 245 | `ZNF791` | TF | 88.77 | 87.99 | 94.79 | 95.45 | 3900 |
339
+ | 246 | `ZNF652` | TF | 88.76 | 88.46 | 95.01 | 94.59 | 15412 |
340
+ | 247 | `GTF2B` | TF | 88.76 | 86.89 | 94.01 | 94.5 | 1890 |
341
+ | 248 | `CBX1` | TF | 88.75 | 87.21 | 94.69 | 92.62 | 12838 |
342
+ | 249 | `KLF4` | TF | 88.72 | 86.04 | 92.03 | 91.82 | 6883 |
343
+ | 250 | `HHEX` | TF | 88.7 | 88.36 | 95.48 | 94.32 | 7808 |
344
+ | 251 | `ZFP91` | TF | 88.7 | 87.92 | 93.44 | 93.1 | 12862 |
345
+ | 252 | `ETS1` | TF | 88.69 | 84.7 | 94.07 | 90.02 | 30554 |
346
+ | 253 | `FOSL2` | TF | 88.66 | 88.52 | 92.87 | 91.8 | 54934 |
347
+ | 254 | `GMEB1` | TF | 88.61 | 86.89 | 94.78 | 94.21 | 22958 |
348
+ | 255 | `MYRF` | TF | 88.61 | 88.08 | 92.66 | 88.81 | 6038 |
349
+ | 256 | `CREB3L1` | TF | 88.6 | 86.11 | 93.55 | 91.45 | 16274 |
350
+ | 257 | `MBD2` | TF | 88.6 | 85.96 | 94.29 | 92.38 | 20596 |
351
+ | 258 | `ZNF384` | TF | 88.58 | 88.42 | 94.86 | 94.74 | 49451 |
352
+ | 259 | `ZNF664` | TF | 88.58 | 88.58 | 94.23 | 93.8 | 26774 |
353
+ | 260 | `SP7` | TF | 88.58 | 87.43 | 93.73 | 92.33 | 43425 |
354
+ | 261 | `AEBP2` | TF | 88.57 | 88.27 | 92.65 | 93.95 | 2439 |
355
+ | 262 | `HOMEZ` | TF | 88.57 | 88.43 | 94.49 | 93.05 | 25047 |
356
+ | 263 | `ZNF514` | TF | 88.55 | 88.75 | 93.62 | 94.15 | 1637 |
357
+ | 264 | `DRAP1` | TF | 88.55 | 87.7 | 93.04 | 91.43 | 23241 |
358
+ | 265 | `HSF1` | TF | 88.53 | 86.77 | 93.77 | 93.41 | 3588 |
359
+ | 266 | `FOXA1` | TF | 88.52 | 88.77 | 94.82 | 94.45 | 144475 |
360
+ | 267 | `KLF10` | TF | 88.52 | 87.13 | 93.65 | 91.19 | 18933 |
361
+ | 268 | `ZNF18` | TF | 88.49 | 87.85 | 93.25 | 92.44 | 18879 |
362
+ | 269 | `GATAD1` | TF | 88.45 | 87.54 | 92.76 | 90.62 | 22354 |
363
+ | 270 | `BRCA1` | TF | 88.43 | 84.43 | 91.88 | 90.63 | 4271 |
364
+ | 271 | `GATA3` | TF | 88.41 | 88.76 | 93.95 | 93.68 | 89323 |
365
+ | 272 | `TBX3` | TF | 88.37 | 86.69 | 92.33 | 87.32 | 16097 |
366
+ | 273 | `HIC1` | TF | 88.34 | 87.87 | 95.07 | 94.7 | 24393 |
367
+ | 274 | `ELF4` | TF | 88.29 | 85.91 | 91.81 | 90.4 | 19552 |
368
+ | 275 | `KLF7` | TF | 88.28 | 87.47 | 95.07 | 95.1 | 11741 |
369
+ | 276 | `MAZ` | TF | 88.25 | 88.01 | 93.3 | 92.34 | 57653 |
370
+ | 277 | `YY2` | TF | 88.25 | 87.53 | 94.5 | 93.99 | 9753 |
371
+ | 278 | `RLF` | TF | 88.25 | 87.22 | 91.97 | 89.17 | 9482 |
372
+ | 279 | `ZNF561` | TF | 88.25 | 87.47 | 92.52 | 89.34 | 21469 |
373
+ | 280 | `HBP1` | TF | 88.25 | 87.02 | 94.35 | 92.31 | 13101 |
374
+ | 281 | `PBX2` | TF | 88.24 | 86.87 | 92.57 | 90.17 | 38883 |
375
+ | 282 | `GATA2` | TF | 88.17 | 88.14 | 93.72 | 92.79 | 71662 |
376
+ | 283 | `ESRRA` | TF | 88.17 | 86.95 | 93.13 | 89.98 | 41619 |
377
+ | 284 | `ZNF189` | TF | 88.17 | 87.09 | 93.99 | 92.74 | 35323 |
378
+ | 285 | `MIER2` | TF | 88.16 | 87.72 | 93.74 | 92.28 | 15598 |
379
+ | 286 | `TBX21` | TF | 88.15 | 87.4 | 94.73 | 94.2 | 38025 |
380
+ | 287 | `DMAP1` | TF | 88.15 | 86.04 | 92.88 | 89.99 | 21794 |
381
+ | 288 | `RFX3` | TF | 88.14 | 87.7 | 92.23 | 93.25 | 6180 |
382
+ | 289 | `FEZF1` | TF | 88.12 | 87.4 | 94.8 | 93.99 | 31350 |
383
+ | 290 | `ZNF248` | TF | 88.12 | 87.31 | 92.8 | 92.85 | 2499 |
384
+ | 291 | `ZNF600` | TF | 88.11 | 87.42 | 93.97 | 90.88 | 45001 |
385
+ | 292 | `NR2F2` | TF | 88.09 | 88 | 95.03 | 94.56 | 55514 |
386
+ | 293 | `ZNF560` | TF | 88.07 | 87.67 | 95.15 | 96.12 | 3447 |
387
+ | 294 | `BHLHE40` | TF | 88.01 | 88 | 92.37 | 91.72 | 90623 |
388
+ | 295 | `NFKBIZ` | TF | 88 | 86.89 | 93.2 | 90.86 | 12731 |
389
+ | 296 | `SOX6` | TF | 87.97 | 87.18 | 92.97 | 91.69 | 36530 |
390
+ | 297 | `NCOA1` | TF | 87.95 | 83.89 | 92.56 | 89.24 | 26193 |
391
+ | 298 | `ZNF2` | TF | 87.94 | 86.44 | 92.68 | 91 | 24945 |
392
+ | 299 | `JUNB` | TF | 87.93 | 88.02 | 92.72 | 91.19 | 51972 |
393
+ | 300 | `KDM4B` | TF | 87.93 | 86.42 | 93.56 | 94.18 | 7803 |
394
+ | 301 | `ZNF10` | TF | 87.88 | 87.16 | 93.83 | 93.93 | 17922 |
395
+ | 302 | `MYB` | TF | 87.86 | 86.65 | 94.72 | 93.1 | 3337 |
396
+ | 303 | `MGA` | TF | 87.84 | 86.5 | 91.45 | 85.5 | 28338 |
397
+ | 304 | `ZBTB2` | TF | 87.82 | 86.59 | 94.58 | 94.15 | 16341 |
398
+ | 305 | `ZEB1` | TF | 87.82 | 85.07 | 94.37 | 93.15 | 20733 |
399
+ | 306 | `REPIN1` | TF | 87.81 | 86.18 | 94.22 | 94.58 | 5721 |
400
+ | 307 | `ZNF148` | TF | 87.79 | 85.69 | 92.13 | 92.12 | 21902 |
401
+ | 308 | `ERF` | TF | 87.78 | 86.48 | 92.92 | 90.58 | 27611 |
402
+ | 309 | `KLF8` | TF | 87.78 | 86.2 | 91.63 | 88.66 | 27450 |
403
+ | 310 | `MYC` | TF | 87.77 | 87.53 | 93.73 | 92.94 | 94483 |
404
+ | 311 | `TRIM22` | TF | 87.77 | 97.99 | 99.03 | 99.13 | 55932 |
405
+ | 312 | `RFX5` | TF | 87.76 | 81.96 | 92.33 | 89.55 | 24728 |
406
+ | 313 | `DACH1` | TF | 87.72 | 87.31 | 92.88 | 92.63 | 18904 |
407
+ | 314 | `ZNF239` | TF | 87.71 | 86.87 | 92.62 | 91.05 | 4689 |
408
+ | 315 | `ZNF366` | TF | 87.69 | 97.9 | 99.1 | 98.73 | 44505 |
409
+ | 316 | `PRDM6` | TF | 87.65 | 87.25 | 94.46 | 92.98 | 42954 |
410
+ | 317 | `ATF3` | TF | 87.61 | 87.36 | 92.96 | 92.73 | 94190 |
411
+ | 318 | `RAD51` | TF | 87.58 | 84.45 | 93.59 | 92.92 | 36133 |
412
+ | 319 | `PRDM4` | TF | 87.55 | 87.06 | 93.45 | 92.04 | 20853 |
413
+ | 320 | `KAT8` | TF | 87.54 | 85.89 | 92.39 | 89.64 | 31059 |
414
+ | 321 | `MBD1` | TF | 87.54 | 84.57 | 92.74 | 88.6 | 18264 |
415
+ | 322 | `PKNOX1` | TF | 87.54 | 87.54 | 94.59 | 94.36 | 113107 |
416
+ | 323 | `WT1` | TF | 87.54 | 86.69 | 92.85 | 89.27 | 26226 |
417
+ | 324 | `CHD2` | TF | 87.52 | 86.08 | 93.75 | 91.52 | 41627 |
418
+ | 325 | `ZXDB` | TF | 87.51 | 86.1 | 91.92 | 88.84 | 30796 |
419
+ | 326 | `HMG20B` | TF | 87.5 | 86.97 | 93.22 | 90.82 | 12656 |
420
+ | 327 | `SIX5` | TF | 87.49 | 79.23 | 89.33 | 86.03 | 10595 |
421
+ | 328 | `MAX` | TF | 87.44 | 87.59 | 92.05 | 89.23 | 94496 |
422
+ | 329 | `TRIM24` | TF | 87.42 | 84.62 | 93.51 | 90.72 | 35639 |
423
+ | 330 | `NONO` | TF | 87.4 | 82.54 | 89.28 | 84.68 | 29192 |
424
+ | 331 | `NFE2L1` | TF | 87.36 | 83.51 | 90.34 | 91.43 | 10261 |
425
+ | 332 | `ZSCAN16` | TF | 87.36 | 87.06 | 92.03 | 89.65 | 6915 |
426
+ | 333 | `ZNF391` | TF | 87.36 | 86.05 | 92.69 | 90.97 | 12610 |
427
+ | 334 | `GATAD2A` | TF | 87.27 | 87.34 | 92.84 | 92.14 | 59253 |
428
+ | 335 | `ZNF282` | TF | 87.23 | 85.73 | 92.1 | 90.4 | 12994 |
429
+ | 336 | `SMC3` | TF | 87.23 | 86.92 | 93.67 | 94.33 | 89498 |
430
+ | 337 | `SMARCA4` | TF | 87.23 | 87.23 | 92.59 | 91.47 | 94655 |
431
+ | 338 | `ZNF645` | TF | 87.19 | 85.99 | 93.82 | 93.71 | 3597 |
432
+ | 339 | `SIRT6` | TF | 87.18 | 86.27 | 91.81 | 89.63 | 831 |
433
+ | 340 | `ZNF205` | TF | 87.17 | 85.68 | 93.89 | 92.45 | 17444 |
434
+ | 341 | `ZBTB11` | TF | 87.17 | 83.11 | 93.24 | 92.37 | 34307 |
435
+ | 342 | `KLF13` | TF | 87.15 | 86.93 | 90.16 | 85.26 | 11590 |
436
+ | 343 | `NKRF` | TF | 87.15 | 82.95 | 93.67 | 92.25 | 27626 |
437
+ | 344 | `OSR2` | TF | 87.15 | 86.49 | 92.7 | 90.29 | 33243 |
438
+ | 345 | `CC2D1A` | TF | 87.14 | 86.24 | 92.24 | 91.48 | 24056 |
439
+ | 346 | `NFIC` | TF | 87.14 | 87.09 | 92.88 | 93.61 | 74803 |
440
+ | 347 | `ZNF138` | TF | 87.12 | 86.79 | 93.04 | 94.92 | 1611 |
441
+ | 348 | `PHB2` | TF | 87.11 | 86.36 | 93.7 | 93.49 | 8362 |
442
+ | 349 | `ZHX2` | TF | 87.11 | 84.59 | 92.57 | 90.95 | 14751 |
443
+ | 350 | `ZNF614` | TF | 87.09 | 86.34 | 92.96 | 90.43 | 21841 |
444
+ | 351 | `ZBTB44` | TF | 87.09 | 86.97 | 91.7 | 89.35 | 19961 |
445
+ | 352 | `ZNF501` | TF | 87.07 | 84.58 | 89.56 | 85.25 | 18650 |
446
+ | 353 | `ZNF547` | TF | 87.07 | 87.18 | 93.08 | 93.55 | 4777 |
447
+ | 354 | `E4F1` | TF | 87.05 | 83.51 | 91.86 | 88.4 | 27783 |
448
+ | 355 | `ZNF530` | TF | 87 | 86.21 | 92.54 | 93.54 | 2193 |
449
+ | 356 | `MYNN` | TF | 86.97 | 85.32 | 92.29 | 90.37 | 19348 |
450
+ | 357 | `INSM2` | TF | 86.94 | 86.19 | 92.8 | 91.74 | 16385 |
451
+ | 358 | `ZBTB7B` | TF | 86.94 | 85.85 | 93.93 | 93.22 | 9156 |
452
+ | 359 | `BCL11B` | TF | 86.93 | 86.01 | 92.01 | 89.38 | 11525 |
453
+ | 360 | `ZBTB12` | TF | 86.93 | 86.23 | 92.9 | 91.71 | 10363 |
454
+ | 361 | `PML` | TF | 86.92 | 85.32 | 93.87 | 93.51 | 18068 |
455
+ | 362 | `SALL2` | TF | 86.9 | 86.55 | 93.23 | 94.22 | 2489 |
456
+ | 363 | `NR2F1` | TF | 86.87 | 86.87 | 93.08 | 92.05 | 70026 |
457
+ | 364 | `LCORL` | TF | 86.86 | 86.86 | 93.26 | 93.83 | 10617 |
458
+ | 365 | `THRB` | TF | 86.86 | 86.05 | 92.7 | 91.63 | 14895 |
459
+ | 366 | `ZGPAT` | TF | 86.84 | 85.13 | 90.76 | 86.79 | 33522 |
460
+ | 367 | `MIER3` | TF | 86.83 | 85.69 | 92.53 | 91.2 | 19565 |
461
+ | 368 | `KMT2B` | TF | 86.81 | 84.82 | 92.77 | 91.54 | 17871 |
462
+ | 369 | `TGIF2` | TF | 86.8 | 85.45 | 92.88 | 90.99 | 18162 |
463
+ | 370 | `IKZF2` | TF | 86.79 | 86.64 | 92.67 | 91.71 | 52015 |
464
+ | 371 | `ZBTB33` | TF | 86.78 | 92.02 | 97.16 | 96.92 | 96111 |
465
+ | 372 | `NEUROD1` | TF | 86.73 | 85.61 | 92.99 | 91.71 | 19165 |
466
+ | 373 | `ATF7` | TF | 86.72 | 86.65 | 92.77 | 93.41 | 105695 |
467
+ | 374 | `SMARCE1` | TF | 86.71 | 86.36 | 92.37 | 91.4 | 48505 |
468
+ | 375 | `RELB` | TF | 86.71 | 84.55 | 93.6 | 91.95 | 36669 |
469
+ | 376 | `ELF1` | TF | 86.71 | 86.32 | 93.8 | 94.5 | 70684 |
470
+ | 377 | `ZNF843` | TF | 86.68 | 85.41 | 92.05 | 89.55 | 22911 |
471
+ | 378 | `ATM` | TF | 86.67 | 85.99 | 93.74 | 94.31 | 2162 |
472
+ | 379 | `ZNF473` | TF | 86.67 | 86.34 | 92.54 | 93 | 2252 |
473
+ | 380 | `MXD4` | TF | 86.63 | 84.43 | 91.34 | 88.33 | 18180 |
474
+ | 381 | `ZNF707` | TF | 86.61 | 86.66 | 93.38 | 93.31 | 3329 |
475
+ | 382 | `CREM` | TF | 86.61 | 86.56 | 92.96 | 93.26 | 72466 |
476
+ | 383 | `ZNF157` | TF | 86.6 | 86.52 | 89.54 | 86.21 | 3778 |
477
+ | 384 | `IKZF3` | TF | 86.59 | 85.8 | 91.99 | 88.04 | 29535 |
478
+ | 385 | `DIDO1` | TF | 86.58 | 85.66 | 92.29 | 92.48 | 7186 |
479
+ | 386 | `ZSCAN26` | TF | 86.56 | 85.08 | 93.43 | 94.67 | 2537 |
480
+ | 387 | `MXI1` | TF | 86.53 | 86.12 | 94.05 | 94.26 | 52982 |
481
+ | 388 | `ZSCAN18` | TF | 86.51 | 85.15 | 92.3 | 92.92 | 4130 |
482
+ | 389 | `CDC5L` | TF | 86.47 | 85.08 | 93.59 | 93.67 | 5151 |
483
+ | 390 | `KLF5` | TF | 86.44 | 85.35 | 92.7 | 90.15 | 11680 |
484
+ | 391 | `ZNF512B` | TF | 86.43 | 83.44 | 93.26 | 91.76 | 8552 |
485
+ | 392 | `LARP7` | TF | 86.42 | 84.12 | 93.32 | 92.81 | 27160 |
486
+ | 393 | `ZNF280C` | TF | 86.42 | 86.07 | 92.27 | 92.66 | 1292 |
487
+ | 394 | `L3MBTL2` | TF | 86.41 | 86.23 | 91.05 | 89.82 | 52245 |
488
+ | 395 | `MCM2` | TF | 86.41 | 85.41 | 93.45 | 94.29 | 4549 |
489
+ | 396 | `ZNF404` | TF | 86.4 | 85.45 | 91.88 | 93.7 | 2249 |
490
+ | 397 | `E2F7` | TF | 86.4 | 85.34 | 91.15 | 91.4 | 2985 |
491
+ | 398 | `MTA1` | TF | 86.34 | 84.24 | 93.57 | 92.13 | 22370 |
492
+ | 399 | `ZNF324` | TF | 86.32 | 84.57 | 93.81 | 93.44 | 14713 |
493
+ | 400 | `GTF2F1` | TF | 86.32 | 83.54 | 92.14 | 90.16 | 39350 |
494
+ | 401 | `RAD21` | TF | 86.3 | 97.92 | 99.11 | 98.99 | 188052 |
495
+ | 402 | `NR2C1` | TF | 86.27 | 81.88 | 90.51 | 85.79 | 31898 |
496
+ | 403 | `RBAK` | TF | 86.25 | 85.74 | 92.56 | 93.16 | 3642 |
497
+ | 404 | `TCF7` | TF | 86.23 | 85.39 | 92.08 | 90.33 | 30462 |
498
+ | 405 | `ZNF776` | TF | 86.23 | 85.19 | 92.22 | 92.04 | 2838 |
499
+ | 406 | `ARHGAP35` | TF | 86.18 | 85.43 | 93.57 | 93.39 | 4817 |
500
+ | 407 | `STAT1` | TF | 86.15 | 83.28 | 92.57 | 90.18 | 11457 |
501
+ | 408 | `ZNF621` | TF | 86.14 | 85.57 | 92.51 | 92.93 | 1976 |
502
+ | 409 | `YBX3` | TF | 86.12 | 84.54 | 90.9 | 90.72 | 2599 |
503
+ | 410 | `ZNF610` | TF | 86.07 | 84.35 | 91.36 | 89.32 | 13333 |
504
+ | 411 | `OVOL3` | TF | 86.05 | 85.14 | 90.46 | 88.66 | 9089 |
505
+ | 412 | `GLI2` | TF | 86.05 | 86.28 | 91.17 | 92.26 | 5650 |
506
+ | 413 | `KLF6` | TF | 86.05 | 84.14 | 91.14 | 87.94 | 15409 |
507
+ | 414 | `ASH1L` | TF | 85.96 | 84.17 | 92.97 | 93.93 | 7269 |
508
+ | 415 | `NR3C1` | TF | 85.91 | 85.89 | 93.29 | 93.1 | 62779 |
509
+ | 416 | `KLF16` | TF | 85.91 | 85.24 | 90.83 | 90.08 | 48641 |
510
+ | 417 | `ZNF114` | TF | 85.91 | 82.83 | 91.36 | 91.57 | 1444 |
511
+ | 418 | `PRDM10` | TF | 85.9 | 86.39 | 91.62 | 88.42 | 68962 |
512
+ | 419 | `ZSCAN29` | TF | 85.87 | 82.16 | 90.3 | 85.84 | 21597 |
513
+ | 420 | `IRF1` | TF | 85.84 | 80.68 | 89.75 | 87.82 | 32357 |
514
+ | 421 | `ZSCAN9` | TF | 85.83 | 84.87 | 91.14 | 89.95 | 17526 |
515
+ | 422 | `ZFP3` | TF | 85.82 | 84.76 | 93.06 | 93.73 | 4550 |
516
+ | 423 | `TAF7` | TF | 85.79 | 81.76 | 93.28 | 92.37 | 21002 |
517
+ | 424 | `MNT` | TF | 85.79 | 85.08 | 92.76 | 93.16 | 83589 |
518
+ | 425 | `ZFP37` | TF | 85.78 | 83.76 | 89.27 | 86.32 | 16553 |
519
+ | 426 | `MZF1` | TF | 85.78 | 85.16 | 91.67 | 89.93 | 17643 |
520
+ | 427 | `TOE1` | TF | 85.74 | 82.45 | 89.5 | 89.69 | 29556 |
521
+ | 428 | `PHF21A` | TF | 85.74 | 85.18 | 88.24 | 82.19 | 8878 |
522
+ | 429 | `BACH1` | TF | 85.62 | 83.64 | 90.78 | 88.15 | 41151 |
523
+ | 430 | `ZNF7` | TF | 85.61 | 84.92 | 92.67 | 92.68 | 8038 |
524
+ | 431 | `ZNF211` | TF | 85.59 | 84.6 | 91.95 | 92.44 | 1919 |
525
+ | 432 | `ZSCAN23` | TF | 85.58 | 84.31 | 92.3 | 91.5 | 8505 |
526
+ | 433 | `FOXM1` | TF | 85.57 | 83.72 | 90.82 | 89.44 | 20757 |
527
+ | 434 | `SUPT5H` | TF | 85.56 | 81.99 | 93.26 | 92.1 | 22469 |
528
+ | 435 | `BCL3` | TF | 85.55 | 83.8 | 93.27 | 92.67 | 43282 |
529
+ | 436 | `TFDP1` | TF | 85.52 | 80.8 | 89.14 | 84.38 | 30292 |
530
+ | 437 | `TAF9B` | TF | 85.46 | 83.58 | 87.02 | 79.88 | 13069 |
531
+ | 438 | `ZNF792` | TF | 85.46 | 83.82 | 92.95 | 91.81 | 24699 |
532
+ | 439 | `SIN3A` | TF | 85.43 | 85.07 | 93.29 | 93.11 | 65597 |
533
+ | 440 | `JUND` | TF | 85.43 | 85.33 | 93.1 | 93.42 | 166033 |
534
+ | 441 | `H3K9me1` | HISTONE | 85.43 | 87.45 | 93.75 | 91.95 | 196657 |
535
+ | 442 | `BCL11A` | TF | 85.41 | 84.36 | 92.15 | 91.13 | 33663 |
536
+ | 443 | `POLR2G` | TF | 85.39 | 84.83 | 92.98 | 93.64 | 59528 |
537
+ | 444 | `H3K23me2` | HISTONE | 85.39 | 85.45 | 93.76 | 93.34 | 77099 |
538
+ | 445 | `NR2C2` | TF | 85.39 | 80.24 | 89.73 | 86.9 | 29811 |
539
+ | 446 | `ZNF571` | TF | 85.34 | 84.53 | 92.7 | 93.55 | 1488 |
540
+ | 447 | `ZNF311` | TF | 85.34 | 84.08 | 92.44 | 93.57 | 2206 |
541
+ | 448 | `EP400` | TF | 85.29 | 82.21 | 89.96 | 88.24 | 25324 |
542
+ | 449 | `ZFP1` | TF | 85.26 | 83.98 | 91.92 | 90.8 | 12129 |
543
+ | 450 | `REST` | TF | 85.25 | 84.97 | 90.84 | 91.49 | 119743 |
544
+ | 451 | `RCOR2` | TF | 85.25 | 84.38 | 90.5 | 88.89 | 19532 |
545
+ | 452 | `SP1` | TF | 85.24 | 84.86 | 91.19 | 91.14 | 120925 |
546
+ | 453 | `MCM3` | TF | 85.24 | 84.32 | 93 | 93.26 | 2561 |
547
+ | 454 | `ZNF169` | TF | 85.23 | 84.36 | 91.23 | 90.6 | 2873 |
548
+ | 455 | `PHF5A` | TF | 85.23 | 82.4 | 90.52 | 88.55 | 9570 |
549
+ | 456 | `TSHZ1` | TF | 85.17 | 84.45 | 92.39 | 91.76 | 11804 |
550
+ | 457 | `MTA2` | TF | 85.15 | 84.91 | 90.5 | 89.57 | 59001 |
551
+ | 458 | `GFI1B` | TF | 85.11 | 84.57 | 91.26 | 90.52 | 10694 |
552
+ | 459 | `ZNF558` | TF | 85.1 | 84.16 | 91.1 | 91.2 | 13849 |
553
+ | 460 | `ZNF19` | TF | 85.06 | 84.17 | 91.34 | 93.34 | 1998 |
554
+ | 461 | `SMAD5` | TF | 85.03 | 79.12 | 92.23 | 90.37 | 22402 |
555
+ | 462 | `SNRNP70` | TF | 85.02 | 82.87 | 89.28 | 89.69 | 871 |
556
+
557
+ ## Model Details
558
+
559
+ | Property | Value |
560
+ |----------|-------|
561
+ | Base model | DNABERT (6-mer, k=6) |
562
+ | Architecture | BERT-base (~340M parameters) |
563
+ | Task | Binary classification (binding/no-binding) |
564
+ | Input | 301 bp DNA sequence (6-mer tokenized) |
565
+ | Training data | ENCODE ChIP-seq |
566
+ | Species | Human (hg38) |
567
+ | License | CC-BY-NC-4.0 |
568
+
569
+ ## Citation
570
+
571
+ ```bibtex
572
+ @article{deepvregulome2025,
573
+ title={DeepVRegulome: DNABERT-based deep-learning framework for predicting
574
+ the functional impact of short genomic variants on the human regulome},
575
+ author={Dutta, Pratik and Sarkar, Shayan and Sathian, Rekha and Tasnim,
576
+ Taharina and Sibi, Sahanya and Sahanya, Samantha and Ghosal,
577
+ Tirthankar and Ay, Ferhat and Zhong, Zhihan and Han, Jiayu
578
+ and Davuluri, Ramana V.},
579
+ journal={arXiv preprint arXiv:2511.09026},
580
+ year={2025},
581
+ url={https://arxiv.org/abs/2511.09026}
582
+ }
583
+ ```