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Browse files- generated_valid_2500.smi +976 -0
- model_eval.ipynb +0 -0
generated_valid_2500.smi
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|
|
|
| 1 |
+
C1C=CC=CC1C(=O)N/N=C/C2=CC=C(C(C)C)C=C2C
|
| 2 |
+
COC=CC1=CC(/C=C/CNC2=C(C3=CC=C(C(F)(F)F)C=C3)N=CN=CC=CN2)C1
|
| 3 |
+
COC1=CC(OC)=CC(=C12)[C@@H1]O[C@H1]([C@@H1](O)[C@H1](O)[C@H1](OS(C)(=O)=O)[C@@H1](OC(C)=O)[C@H1]2)O[C@H1](O)[C@H1](O)[C@H1]O
|
| 4 |
+
O=COC1C(=O)OC(OC(=O)CC(C)C2)CC3(OC3)C1(C)C(O)CC4(C)C(C5=C6OC=C5)CC7OC47C6(C)C(OC(=O)C)C2C
|
| 5 |
+
COC1=CC2=C(C=C1OC)C(C3=CC4=C(C=C3O)OCO4)NCC2
|
| 6 |
+
CN(C)/C(=N\C1=CC=C(F)C(F)=C1)C(C(=O)NCC2=CC=C(F)C=C2)C3=CC=C(F)C=C3
|
| 7 |
+
COC1=CC2=CC(=C1)CCNC[C@H1](C(=O)N(CC3=CC=CC=C3)CC4=CC=CC=C4)[C@@H1](CC(C)C)C2=O
|
| 8 |
+
COC1=CC=CC=C1OCC2=NN=C3SC(CCC(=O)NC4=CC(C)=CC(C)=C4)=NN23
|
| 9 |
+
CC1=CC(C(=O)NCC(=O)NCCC2=CC=CC=C2)=CC=C1S(=O)(=O)N3CCCC3
|
| 10 |
+
O=C1NC(=O)C(C2=CC=C(Br)C=C2Br)(C1)C(=O)N/N=C/C3=CC=C(F)C=C3
|
| 11 |
+
C=CCOC=CC=C1C(C(=O)N(CC2=CC=C3C=C(N(CC)CC)CC3=C24)C=CC(=C(C)C)C)=C4C1
|
| 12 |
+
CC1=CC=CC=C1O[C@@H1](CN2CCC3=CC(NS(C)(=O)=O)=CC=C32)CF
|
| 13 |
+
CC(=O)N[C@@H1](C)C1=CC=C(O[C@@H1]2CCN(C3=CC=NC(N(C)CCN(C)C)=N3)C2)C=C1
|
| 14 |
+
O=C(O)CCC1(OC(=O)COC)CCC(C)C2C1C34CC5C6(C)CCC(C(=C)C6)C(COC(=O)C)C5CCC3(CO)CCC24
|
| 15 |
+
CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+1](=O)[O-1])=C1
|
| 16 |
+
O=C(O)CC1CCN(C(=O)C(N)C)CC1CCN2CCN(C3=NC=CC=N3)CC2
|
| 17 |
+
C1OC=CC=CC1C(=O)NC2=CC=C(CN3CCN(C)CC3)C(OC)=C2C
|
| 18 |
+
CC1=CC=C(NC(=O)N(C)CC2=CC=C(F)C(C(F)(F)F)=C2)C=C1NC3=NC=CC(C4=CC=CN=C4)=N3
|
| 19 |
+
CCOC=CC=C(C=C(O)N=CC1=C(Cl)C=C(C2=C(F)C=CC=C2C#N)C=C1C=CO)CC
|
| 20 |
+
COC1=CC=C([C@@H1](C)N2C(=O)OC[C@H1]2C3=CC=CC=C3Cl)C(OC)=C1
|
| 21 |
+
CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC=C1C(O)=CC=2OC(C3=CC=C(O)C=C3O)=C(C)C1=2
|
| 22 |
+
COC1=CC=CC(S(=O)(=O)N2CCC3=CC=CN=C3N(C)C2C)=C1
|
| 23 |
+
CN(C(=O)C1=CC=C(S(=O)(=O)NC2=CC=CC=N2)C=C1)C3=CC=CC=C3
|
| 24 |
+
O=C(O)CCCC1C2C3C4(CCCCCCC=5C=CC6=C(C=5)N7N=C(C=CC7CCCCCC)C8=CC=CC=C8CCC2C6C=C9C4CC%10(CCCC%10)C9C3CCCCNC)C1
|
| 25 |
+
CC(=O)NC=C1C=CC(NC2=NC=NC3=CC=C(NCC4=CC=C(N(C)C)C=C4)C=C23)=C1
|
| 26 |
+
CCCCCCCCNC(=O)[C@@H1]1CCCN1C(=O)OC
|
| 27 |
+
CCOC(=O)C(C)N1C(C=CC2=CC=CC(OC)=C21)N
|
| 28 |
+
COC1=CC=C(C(=O)C2=CN=CC(OC3=CC=C(O)C=C3)=C2)C=C1OC
|
| 29 |
+
CC(C)(C)NC1=NC(N)=NC(C(F)(F)F)=N1
|
| 30 |
+
C=C[C@@H1]1C[C@]1(NC(=O)[C@@H1]2CN(S(=O)(=O)C3=CC=C(C)C=C3)C[C@H1]2C(=O)NS(=O)(=O)C4(C)CC4C(=O)C=O)N5CCC[C@H1]5C(=O)N[C@H1](C=O)CCCCN(C)C
|
| 31 |
+
CC(C)(C)C(=O)NCC1=CC=C(C2=CC=CN=C2C(F)(F)F)C=C1C(F)(F)F
|
| 32 |
+
C=CCOC(=O)NCC1=CC=C(OC)C(Cl)=C1
|
| 33 |
+
CC(OC1=CC=CC=C1C(F)F)F
|
| 34 |
+
CC(C)(C)NC(=O)N1C=C(C2=C(O)C3=CC=CC=C3[NH1]C2=O)CC=C(O)C(O)=CC1=O
|
| 35 |
+
CCOC(=O)C1=C(CSC2=CC=C(Cl)C(Cl)=C2)[NH1]C3=CC(Cl)=CC(Cl)=C13
|
| 36 |
+
CC1=CC=CC(Cl)=C1NC(=O)CN2CCO[C@@H1](C3=CC=C(F)C=C3)C2
|
| 37 |
+
CC1=CC=CC(N2CCC(OC(=O)C(C)NC(=O)OC(C)(C)C)C2=O)=C1
|
| 38 |
+
OC[C@@H1]1CCCCN1C2=NC=C(N3CCN(C4CCCCC4)CC3)C=N2
|
| 39 |
+
COC=C1C=CC(C2=NC3=CC=CC=C3N2CC4=NN=C(NC5=CC=C(F)C=C5)S4)=C1
|
| 40 |
+
O=C(N1C[C@H1](OC(=O)N2CCN(C3=NC4=CC=CC=C4S3)CC2)C[C@H1]1C5=CC=C(Cl)CCl)C5NCC6=CC=CO6
|
| 41 |
+
CCOC(=O)C1=C(F)C=CC=C1S(=O)(=O)N2CC(C(=O)NC3=CC=C(Cl)C=C3Cl)C2
|
| 42 |
+
COC=CC(O[C@@H1]1O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]1O)=C2C(=O)C3=C(OC)C=CC=C3OC2
|
| 43 |
+
C#C[C@](O1)CC[C@H1]2[C@@H1]3CCC4=CC(=O)C=C[C@]4(C)[C@H1]3CC[C@@]21C
|
| 44 |
+
COC(=O)C1=CC=C([N+1](=O)[O-1])N1C(=O)NC2C=CC=C(NC(=O)C3=CC=CC(S(=O)(=O)NC(=O)C4=CC=CC=C4Cl)=C3C)C2
|
| 45 |
+
C1OC(=O)C=CC=C1[C@H1]2C=3[NH1]C4=CC=CC=C4C=3C[C@@H1]C(=O)N(C)CC(=O)N2
|
| 46 |
+
C1C=CC=C(CN(C)S(=O)(=O)C2=CC=CC(C(F)(F)F)=C2C)C1
|
| 47 |
+
O=CNC(=O)C=C1C=CC(NC(=O)C=NOCC=C2C=C(NC(=O)C3=CC4=CC=CC=C4OC3)OC=C2)=N1
|
| 48 |
+
O=C(O)CCC1CN(C(=O)COC)CCC1CC=NCC=2C=CC(OC)=CC=2N
|
| 49 |
+
N[C@H1](CNC(=O)N1CCN(C2=CC=NC(F)=N2)CC1)CC3=CC(F)=C(F)C=C3F
|
| 50 |
+
C1OC=CC=CC(CNN=NC1C=CC=C(S(=O)(=O)N(C)C(=O)CC(C)(C)F)C=N)=C
|
| 51 |
+
CC(=O)NC(=O)C(O)C(O)C(O)CO
|
| 52 |
+
C1C=CC=C1CN(CC2=CC=CC=C2)S(=O)(=O)C3=CC(C)=C(C)C=C3C=C
|
| 53 |
+
O=C1C2=CC=CC=C2SN1CC3=NN=C(CNC4=CC=CC=C4C5=CC=CC=C5)O3
|
| 54 |
+
CC(C)C1=CC(Cl)=CC(Cl)=C1OCC(O)CN
|
| 55 |
+
COC=CC=CC([C@@H1]1C[C@@H1](C(F)(F)F)NN(C2=CC=C(OC(F)(F)F)C=C2)C(=O)N1)=C
|
| 56 |
+
O=C(O)C1=CC(O)=C(O)C(O)=C1C2=C(O)C(O)=C(O)C3=C2C(=O)OCC3OC(=O)C=CC4=CC=C(O)C=C4
|
| 57 |
+
CCN(CC)CCCNC(=O)C1=NN(C2=CC=C(Cl)C=C2)C(=O)C3=C1C4=CC=CC=C4N3CC5=CC=CC=C5
|
| 58 |
+
CS(=O)(=O)NC1=CC=C(C2=CC=NC(NC3=CC=C4C(=C3)OCCO4)=N2)C=C1
|
| 59 |
+
CC(C)C=C1C=C(NC(=O)OC2=CC(C3=CC=C(C(C)(C)C)C=C3)=CC=C2)C=C1
|
| 60 |
+
CC(C)C(=O)NCCC(N1N=C(CC2CCCC2)C=C1C(=O)NCC3=CC=CC=N3)C
|
| 61 |
+
CCC1CCC(NC2CC3OC3CCCC2O)C1=O
|
| 62 |
+
COC1=CC=CC=C1C2=NN(C3=CC=CC=C3)[C@H1](C4=CC=CC5=CC=CC=C45)C2
|
| 63 |
+
CC1=C2C=C(NC(=O)CSC=NN=C2C(=O)NCCOCCO)O1
|
| 64 |
+
COC1=CC=C(C=C1NC(=O)C2=CC(C3=CC=CC(OC)=C3)=CC=C2CCC(=O)OC)COC
|
| 65 |
+
C12C=CC(C(=O)NC=CC=C(F)C1(NC(=O)C3=CC(C(F)(F)F)=CC=C3[NH1])N)N2C
|
| 66 |
+
COC1=C2C=C(C=C1Cl)C(C(=O)OC)=C(N)O[C@@H1](C3=CC=CC(NCC)=C3)C2
|
| 67 |
+
CCOC(=O)C1=CC=C(C2=CN3C=CC=CC3=N2)C=C1
|
| 68 |
+
CC1=CC=CC=C1NC(=O)CN(C)C(=O)C2=CC=C(CC3=CC=CC=C3)C([N+1](=O)[O-1])=C2
|
| 69 |
+
CCCCCNC(=O)OC1=CC=CC(C(C2=CC(C(C)=O)=CC(C(C)=O)=C2)C3=CC=CC=C3C(=O)OCCOC)=C1
|
| 70 |
+
C=N[C@H1][C@@H1](C[C@@H1]C1(C2=CC=CC=C2)CCCCC1)CO
|
| 71 |
+
COC1=CC=CC=C1NC(=S)N/N=C2\C(=O)NC3=CC=C(C)C=C32
|
| 72 |
+
O=C1C2=CC=CC=C2C(=O)N1CCN3CCCC4(C3)OCCO4
|
| 73 |
+
CC(C)CC1OC2=CC=C3C=CC=CC3=C2C=C(C(=O)NS(=O)(=O)C4CC4)C(=O)N1
|
| 74 |
+
CC1=CC(NC2=NC=C(Cl)C(NC3CC(F)(F)C3)=N2)=CC(N4CCN(C)CC4)=C1
|
| 75 |
+
O=COCCC1(OC(=O)C2(OC(=O)C=3C=CC=CC=3C(=CCC4=CC(OC)=C(O)C(OC)=C4O)C12)CCC5=C)C(OC)=C(O)C=C5CCC6(O)CCCC6C
|
| 76 |
+
O=COC1(C(=O)OC2=C3C4OC(CC4)C(O)(C)CC3C=C2C1(C)CCC5C)C6CC(OC(=O)C)C5C6(C)CCC(C)C
|
| 77 |
+
C1OC=CC=C(NC2=NC(NCC3=CC=CO3)=C4C=CC=CC4=N2)C1OC
|
| 78 |
+
C1C=CC=C1N(C(=O)C2=CSN=N2)C(C(=O)NCC3=CC=CO3)C=CC=NC=C
|
| 79 |
+
CC1=CC(/C=N/NC2=NC(C3=CC=CO3)=CS2)=C(C)N1C4=CC=CC=N4
|
| 80 |
+
O=CC1=C(C=C(C=C1OC(CC(=O)OC)CC)CC=C)CC
|
| 81 |
+
CC(=O)N[C@H1]1[C@H1](O[C@@H1]C2(CNC3=C(F)C(F)=C(F)C(F)=C3)O[C@H1](CO)[C@@H1](O)[C@@H1]2)OO[C@H1](CO)[C@@H1](O)[C@@H1]1O
|
| 82 |
+
O=C1NC(C(=O)NC1C2=CC=CC=C2Cl)CC3C4=CC=CC=C4NC3(C)C
|
| 83 |
+
COC=CC=C(/C=C/C1=NC2=CC=CC=C2N1CC3=CC=CC=C3C)C
|
| 84 |
+
C1CO[C@H1](CN(C)CC2=CC=C(C3CCCC3)C=C2)[C@@H1](C(=O)NC(C)(C)C)C1
|
| 85 |
+
OC1=NOC(CCNC2=CC(Br)=C(Cl)C(C3=CC=CO3)=C2)C1
|
| 86 |
+
O=C1NCN(C2=CC=CC=C2)C13CCN(CCCCN4CCC(N5CCOCC5)CC4)CC3
|
| 87 |
+
CC(N)CC1=CC=C(Cl)C=C1
|
| 88 |
+
CN(CC1=CC=CC=C1)C(=O)C2=CC=C(OCCCC3=CC=C(F)C=C3)C=C2
|
| 89 |
+
CC(C)CC1=CC(S(=O)(=O)N(C)C)=CC=C1N2CCC(NC3=CC=C4C(=C3)CCC4)CC2
|
| 90 |
+
CN1C(C2=CC=C3C=CC=CC3=C2)=NN=C1SCC(=O)NC4=CC=C(N5CCOCC5)C=C4
|
| 91 |
+
CC=CC=CNC(=O)CNC(=O)CCN1N=C(C2=CC=C(C)C=C2)C3=CC=CC=C31
|
| 92 |
+
C1N(C)[C@@H1]C(O)=C(C(N)=O)C(=O)[C@@](O)C(O)=CC(=O)C=C(O)C(NC2CCCCC2)=C1C[C@@H1](O)CNCCCC3=CC=CC(C(=O)NC4=NC=CS4)=C3N=C
|
| 93 |
+
CC1=CC=C2C=C1C(O3)=CC(=O)N(/N=C\C4=CC=CC([N+1](=O)[O-1])=C4C)CC3=C2
|
| 94 |
+
CC(C)C(NC(=O)C1=CC(OCC(F)(F)F)=C(Cl)C(NCC2=CC=CN=C2)=C1)C(=O)O
|
| 95 |
+
COC1=CC(OCC2=CC=CC=C2)=CC=C1/C=C/C3=CC=C(O)C(OC)=C3
|
| 96 |
+
C1C(C)C(=O)C(=C/C(=C\C=2N=C[NH1]C=2CC(C)C1)C)CC(C)C
|
| 97 |
+
O=COCC(C1)CC(OC)(C(=O)CC(O2)=C(C=C3C=CC(OC)=CC3(OC)CC2C(=O)C(C)C1OC(=O)C4COC)CC(O)C4OC(=O)CCC5=C)C=CC=C5
|
| 98 |
+
CN1C(NCC2=CC=C(OCC3=CC=CC=C3)C=C2)=CC(=O)N(C)C1=O
|
| 99 |
+
CCCCCCN(CC1=CC=C([N+1](=O)[O-1])C=C1)S(=O)(=O)C2=CC=C([N+1](=O)[O-1])C=C2
|
| 100 |
+
COC1=CC=CC=C1N(C)C(=O)[C@H1](CC2=CC=CC=C2)NC(=O)[C@@H1](C)N
|
| 101 |
+
COC=CC=C(OC)C(NC(=O)C1NC(=O)N(CC2=CC=CC(C)=C2)C1)=O
|
| 102 |
+
CC(NC(=O)C1=NC=CC(Cl)=C1)C(=O)N2CCOCC2
|
| 103 |
+
C1C=CC=C1C2=CN=C3N=C(NC=C4C(C5CC5)=N[NH1]C4)CC3=C2C=C
|
| 104 |
+
CC(C)C1=CC=C2C(=C1)O[C@@H1](CNCCCCCCCCCN[C@H1]3C4[C@](C)CC[C@H1](O)[C@]5(CO5)[C@@H1]4CC[C@@]3C)O2
|
| 105 |
+
COC1=CC=CC(C2C(C(=O)C3=CC=CS3)=C(O)C(=O)N2CC4CC4)=C1
|
| 106 |
+
O=C(O)CCC(N=C(O)C(N=C(O)CC1=CC=C(O)C(=C1)CCC)CNCC(=N)N)C(=O)O
|
| 107 |
+
COC1=CC(C(=O)C2=CSC(C3=CC=C(C)C=C3C)=N2)=CC=C1O
|
| 108 |
+
CN1C=NN=C1SC2=CC=C(Cl)C(Cl)=C2
|
| 109 |
+
O=C(OCC(C)C1(OC)C=COC(OC=C(C2=O)C(OC3=CC(O)=C4C(=O)C=C(C(=O)C4=CC(OC)=C2)C(CCC(=O)[O-1])CO)C3OCO)(C)C(O)C1)OC
|
| 110 |
+
C1OC=CC=C(N2C(=O)C(=O)/C(=C/C3=CC=C(Cl)C=C3Cl)C2=O)C1OC
|
| 111 |
+
CC(C)C(NC1N=CC=C(C(=O)NCC2=CC=CC=C2)N1)C(=O)NC3CCCCC3
|
| 112 |
+
O[C@@H1](CN1CCC2=C([NH1]C3=CC=C(Cl)C=C23)C1)CNC4=CC=C(Cl)C=C4
|
| 113 |
+
CCN(CC)C(=O)CO/N=C(\CCN1CCN(C2=CC=CC=C2Cl)CC1)C3=CC=C(Cl)C=C3Cl
|
| 114 |
+
CC1=CC=CC(C(=O)NC2=NC(C3=CC=C4C(=C3)OCO4)=NS2)=C1
|
| 115 |
+
O=C(N)NCCCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C1N(C(=O)C2NC(=O)CC2)CCC1)CC3=C)C=CC=C3CC(=O)NCCC4=CC=C(O)C=C4)CC5=CN=C)[NH1]5)OC=O)OCC=O)O
|
| 116 |
+
C1OC=CC=C1C=2N=C3C(OCC4=CC=C(F)C=C4F)=CC=CN3C=2CN5CCOCC5C
|
| 117 |
+
CC=C1C=C(NC(=O)C=C2C=C(CN3C=C(C4CC4)N=N3)C=C2)C=C1C
|
| 118 |
+
CC1=CC=CC(NC(=O)[C@H1]2C[C@H1]2C3=CC=CC=C3)=C1
|
| 119 |
+
O=COC1=CC=C(C=C1OC)C=2OC3=CC(OC)=CC=C3C(=O)C=2OC(C4=CC=C(F)C(Cl)=C4)CC(=O)OCC
|
| 120 |
+
O=C1NC(=O)N(C2=CC=CC=C2)C(=O)/C1=C\C3=CC=CC=C3
|
| 121 |
+
C[S+1]([O-1])C1=CC=C(CNC(=O)C(=O)N/N=C/C2=CC=C(Cl)C=C2F)C([N+1](=O)[O-1])=C1
|
| 122 |
+
O=CNC(=O)C=C1C=C(C2=CC=C([N+1](=O)[O-1])C=C2)C3=CC=CC=C31
|
| 123 |
+
CN(/N=C/C1=CN(CC2=CC=CC=C2)C3=CC=CC=C13)C4=NC5=C(F)C(F)=C(F)C(F)=C5S4
|
| 124 |
+
CCCN(CCC)C(=O)C1=CC(OC)=C(OC)C=C1C(C2=CC=C(F)C=C2)C
|
| 125 |
+
CN(CC1=CC=CC=C1)C(=O)CC23CC4CC(CC(C4)C2)C3
|
| 126 |
+
COC1=CC=CC(/C=N/NC(=O)C2=CC=C(F)C=C2)=C1O
|
| 127 |
+
COC=CC1=CC(C(=O)NCCC(C)(N2CCC(NCC3=CC=C(OC)C(OC)=C3)CC2C)CC=O)OC=C1
|
| 128 |
+
CCOC=CC=C(NC(=O)CC(C)S(=O)(=O)C1=CC=C(Cl)C=C1C)C
|
| 129 |
+
N[C@H1]C[C@H1]1CN(CC2=CC=C(C3=C(F)C=C(F)C=C3F)C4=C2)C(=O)N14
|
| 130 |
+
C1CC2CCCCN2CCNC(=O)CC=NN1C=CC=C(NC3=NC=CC(N4C(=O)OC[C@@H1]4C(C)C)=N3)C(F)=C
|
| 131 |
+
CCOC(=O)C=C(C)N=CC=CC(C)=C(N1CCN(CC2=CC=C(S(C)(=O)=O)C=C2)CC1C)C=O
|
| 132 |
+
CCO/C(C)=C1/C(=O)N(C(C)=O)C(C2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)CC1C4=CC=C(Cl)C=C4
|
| 133 |
+
CN(C(=O)C1=CN=CN=C1)[C@H1]2CCOC2
|
| 134 |
+
C=C1CN(CC=C)C2=C1C(=O)C3=CC=CC=C3C2=O
|
| 135 |
+
O=C(OCCC1(C)C(CC(O)C2OC(OCC)C(O)C(O)C12C)C3CCC(C(=C)C)C3)CC
|
| 136 |
+
C1COC(=O)NC=CC=C(OCC)C1NC(=O)COC2=CC=C3C(=C2)CNCC3=C
|
| 137 |
+
O=COCCC12C(C)C(C(=O)C1C(O)CC3C(O)(C)C(C)CCC23C)(C)CC
|
| 138 |
+
CCCCCCCC(C)(CC(=O)[O-1])C[N+1](C)(C)C
|
| 139 |
+
COC(=O)C1=CC=C(OC(=O)C2=CC=CC(C3=CC=CC(CN4CCC(C(=O)O)CC4)=C3)=C2)C(Br)=C1
|
| 140 |
+
COC1=CC(NC(=O)[C@H1]2C[C@@H1]2C)=CC=C1C3=C(F)C=C(C4=CC=C(NC(C)=O)C=C4)C=C3F
|
| 141 |
+
CN(C/C=C/C1=CC=C(C=2C=CSC=2)C=C1)C3=CC=CC=C3
|
| 142 |
+
COC=CC(C1=CC=C(C2=CC=C(F)C=C2Cl)C(Cl)=C1)F
|
| 143 |
+
CCN(CC)CC1=CC(S(=O)(=O)N(C)C)=CC(C(F)(F)F)=C1
|
| 144 |
+
COC1=CC=C2C(=C1)CN(C(=O)C3=CC=C(C)S3)CC2C4=CC=C(SC)C=C4
|
| 145 |
+
O=C(O)C1=CC(C2=CC=C(OC3=CC=CC=C3)C=C2)=CC=C1O
|
| 146 |
+
O=P(O)(O)O[C@@H1]1CC[C@H1](NC2=NC(NC3=CC=CC=C3)=NC4=CC=CC=C24)[C@H1]1O
|
| 147 |
+
O=COCCOC(=O)CC=C1CC=C(OCOC=C2C(=O)OCC(OC(=O)C=3C=CC=CC=3C)OC2OC4OC(C)C(OC5OC(C)C(O)C(O)C5O)C(O)C4OC(=O)C=6C(O)=CC(O)=CC=6[OH1+1]C)C=C1C
|
| 148 |
+
C1C(=O)NC=CC=CC1C(=O)C2=CC=C3C(=C2)C(C)=C(C)N3CC(=O)OC
|
| 149 |
+
O=COC(COCCC(OC(=O)C)CCCC)(O)C(O1)CCCC23CC(C(=C)C2O)CCC13C
|
| 150 |
+
C1OC=CC=C1OCC2=NOC3=NC(C(F)(F)F)=NC=C23
|
| 151 |
+
CN1C(C2=CC=C(F)C=C2)=CN=C1N3CC4CC3CC4
|
| 152 |
+
COC=CC1=C(C2=CNC(=N2)SC=C3C(NC(=O)CCN4CCOCC4)=CC=C3)C=C1
|
| 153 |
+
COC1=CC(C(=O)OCC(=O)NC(=O)C2=CC=CC=C2F)=CC(OC)=C1OC
|
| 154 |
+
CC(=O)NC1=CC=CC(C(=O)OC[C@H1]2CCCN2S(C)(=O)=O)=C1
|
| 155 |
+
C1OC(=O)C=C2C=C(CNCCCC1(NCCC3=CC=C(OC)C(OC)=C3C)OC)C2
|
| 156 |
+
O=COCCC1(C2)C(OC(=O)C)C(=O)C(C(O)OC2(O)C=C(COC(=O)C)C(C)C1OC=O)CC
|
| 157 |
+
COC1=CC=CC=C1NC(=O)N2CC(F)(F)C2
|
| 158 |
+
O=C1C=CC=CN1CCCNC(=O)C=C2CC(=CS2)CC=CC=3OCCOC=3C
|
| 159 |
+
CCCCCCCCCCCC1CS[C@H1]O[C@H1][C@@H1](O)[C@H1]1O
|
| 160 |
+
N[C@H1]1CC[C@H1](NC2=CC(N3C=NC=C3CN4CCN(CC5=CC=CC=C5)CC4)=CC=C2C(F)F)CC1
|
| 161 |
+
C1=CN=C2N=C(NCCC3=CC=C(F)C=C3)SC2=C1
|
| 162 |
+
OC1=CC(OC)=C(OC)C(O)=C1C
|
| 163 |
+
COC1=CC=CC=C1CN(CC(O)C2NC(=O)N(C3=CC=C(OC)C=C3)C2=O)S(C)(=O)=O
|
| 164 |
+
O=C(OCCC1C2(C)C(CCC3(C)C2CC4C5CC(C)(C)CCC5(C)CCC43)CC1)CCCCCCCC
|
| 165 |
+
O=COCC1OC=2C=3OCOC=3C=CC=2C(=O)C(C)(CC=C(C)C)CC1C(=O)OCC
|
| 166 |
+
CC1=CC=C(OCCN(C)CC2=CN=C3[NH1]C=CC3=C2C)C=C1
|
| 167 |
+
CCN(CC)CC1=C(F)C(C2=CC=CC=C2)=NC(N(C)C)=N1
|
| 168 |
+
C1C(=O)NC=CC=CC1OC2=C(C(C)(C)C)C=C(C3=CC=CC=C3)C=C2C(N)=O
|
| 169 |
+
CCCCCN(CC(=O)NC1=CC=CC=C1C)C(=O)CCC(=O)N(CCC2=CC=C(OC)C(OC)=C2)C
|
| 170 |
+
N=1OC(=CC=1CC2(NCC3=NN=N[NH1]3)COC2)C4=CC=C(CC5=NOC(=N5)C6=CC=CC=C6)C(F)=C4
|
| 171 |
+
CNC1[C@@H1]OC[C@@H1]1C2=CC=C(C(F)(F)F)C=C2
|
| 172 |
+
COC=CC=C(CC(=O)NC1=CC=CC=C1C(=O)C=2[NH1]C3=CC=CC=C3C=2CCC(=O)NC)C
|
| 173 |
+
CC1=CC=C(C(O)C2=NC(C3=CC=C(C#N)C=C3)=C[NH1]2)C=C1
|
| 174 |
+
COC1=CC=C(C2=N[NH1]C(=O)O2)C(O)=C1OCC(=O)O
|
| 175 |
+
COC1=CC=C(S(=O)(=O)N(CC(=O)NC2CCCC2)C3=CC=C(F)C=C3F)C=C1
|
| 176 |
+
CC1=CC=CC=C1C(=O)N2CCC(N3C=C(C(=O)NCC4=CC=C(Cl)C=C4)N=N3)CC2
|
| 177 |
+
O=CC1=C(NC2C(F)=CC=3C=CC=CC=32)CC(C)C14OC=5C(Cl)=C(OC)C=C(OC)C=5C4=O
|
| 178 |
+
CN1C=NN=C1SCC(=O)NC2CCCC(OC(=O)C3=CC=CO3)C2
|
| 179 |
+
CC=C1C=C(C(C)N[C@H1]2CC[C@H1](NC3=NC4=CC=CC=C4S3)CC2)C(F)=C1
|
| 180 |
+
COC1=CC=C(C=C1C=NC(C)=C(/C=C/C2=CC=C(OC)C=C2)[NH1])CO
|
| 181 |
+
COC=C1C=CCC(CC2CCN(CCC3=CC=C(F)C=C3)CC2)=CN(C)C(=O)C1
|
| 182 |
+
CC(C)CCN(C(=O)C1=CC=C(COC2=CC=CC=C2)C=C1)C3=NC4=C(C(=O)N(C)C(=O)N4C)N3CCCC
|
| 183 |
+
C1OC=CC=C1C2CC(C3=CC=CO3)=NN2C(=O)C4=CC(C)=C(C)S4C=C
|
| 184 |
+
C1C=C2C1(NC(=O)CNC(=O)COC3=CC=C(S(=O)(=O)N4CCCCC4)C=C3)NO2
|
| 185 |
+
COC1=CC=CC(C=2OC=NC=2C3=CC(C4=CC=C(F)C=C4)=N[NH1]3)=C1
|
| 186 |
+
CCCCCCCCCCCCCCCCCCCCCCCCC(=O)O[C@H1](CO[C@H1](N)C[C@@H1](O)[C@H1](O)CO[C@@H1]1O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]1NC)CC=O
|
| 187 |
+
COC=CC=CC1=CC=C2N=CN(C3=CC=C(C(C)(C)C#N)C=C3Cl)C2=C1C=C
|
| 188 |
+
OC(C12CNC(C3=CC=C(C(F)(F)F)C=C3)=N1)CN(CC4CC4)CC2
|
| 189 |
+
COC=CC1=C(CN2C(C3=CC=C(OC)C=C3)=CC(=O)C=4[NH1]C(C5=CC=CS5)=NC=42)C=C1
|
| 190 |
+
O=C(O)C1=CC=CC(=C12)NC(=O)CC(OC)=CC(O)=C(C(=O)C(C(=O)OC)CC3=C(OC)C=C(O)C=C3CC2)CC
|
| 191 |
+
COC1=CC=CC2=C1C3=CC=C(N)C=C3C(=O)N2C4=CC=CC=C4
|
| 192 |
+
COC(=O)C1=CC=C(NC(=O)CCC2=CC=CC(OC)=C2)C=C1
|
| 193 |
+
CC(C)(C)OC(=O)N[C@H1](C(=O)NC(C1=CC=CC=C1)C2=CC=C(C(F)(F)F)C=C2C)CC(C3CCCCC3)C
|
| 194 |
+
COC1=CC=CC=C1OCCN2CCC(N(CC3=CC=CC=C3)S(=O)(=O)C4=CC=C(F)C=C4)CC2
|
| 195 |
+
COC1=CC=CC(NC(=O)C2=CC=CC(O)=C2C(=O)O)=C1
|
| 196 |
+
CCCCCCCCCCCCCCCC(=O)NCCCC(N)CC(=O)O
|
| 197 |
+
C1CCCC(=O)N[C@H1]C(=O)O[C@H1]1C(=O)NC(CC(N)=O)C(N)=O
|
| 198 |
+
CCCCCCCCCCCCCCCC(=O)OC[C@H1]1O[C@@H1](N2C=NC3=C(N)N=C(OC)N=C32)[C@H1](O)[C@@H1]1O
|
| 199 |
+
COC(=O)C1=CC=C(/C=C/C2=NC3=CC=CC=C3C(=O)[NH1]2)C=C1
|
| 200 |
+
C1C(C)CC(=O)N(CC2=CC=C(C3=CC=CC=C3)C(Cl)=C2)C1
|
| 201 |
+
CCCCCCCCCC[N+1]=C1C=C(C(=O)NCCCCCCCCCN2C=CC(=CCNCN)OC2)C=C1
|
| 202 |
+
CC1OC=CC=C(N(C(=O)C=2SN=NC=2C)SS(=O)(=O)C3=CC=CC4=C(N(C)C)C=CC=C34)C1
|
| 203 |
+
CC1=CC=C(C=C2C(/C=N/C3=N[NH1]C=NC=NC(N)=C3)=CC=N2)O1
|
| 204 |
+
CC(C)(C)NC(=O)CCC1=CC=CC=C1
|
| 205 |
+
CCOC=CC1=C(C(=O)NCCCNC2CC(C(=O)N[C@H1](CC3=CC=C(F)C=C3)C(=O)NCCC4=CC=C(OC)C=C4)C)C2C=C1
|
| 206 |
+
COC1=CC=C(NC(=O)C=2C=C(C3=CC=C(C#N)C=C3)ON=2)C=C1
|
| 207 |
+
CC1=CC=CC(NC(=O)C2CCN(C(=O)C3=CC=CO3)CC2)=C1
|
| 208 |
+
CCOC1=CC=C(C2=CC(C)=C(NC(=O)C3=CC=C(CC#N)C=C3)C(C)=C2)C=C1
|
| 209 |
+
CCCCCC(=O)NC1=NC(C2=CC=CO2)=NN1C
|
| 210 |
+
CCOC(=O)/C(F)=C(/[C@H1])NC(=O)[C@H1]([C@@H1](C)CC)OC(=O)[C@H1]([C@@H1](O)CC(N)=O)NC(=O)[C@H1](CC(C)C)NC(=O)[C@@H1](C)[C@@H1](O)[C@@H1](C)C[C@H1](C)/C=C/C=CC
|
| 211 |
+
O=C(OCC(OC(=O)CCCCCCCC=CCCCCCCCC)COP(=O)(O)OCC(OC1OC(CO)C(O)C(O)C1OC2OC(CO)C(O)C(O)C2OCO)COCOCCCCCCCCCCCCCCCC)CCCC
|
| 212 |
+
CCO/C(O)=C\C(C)=NC=C(C(=O)N(C)CC1=CC(F)=C(F)C=C1)F
|
| 213 |
+
CC1(C2=CC(Cl)=CC(Cl)=C2)CCC(=O)N1CC3=CC=C(Cl)C=C3
|
| 214 |
+
N/C(=N\O)C1=CC2=NC=C(NC3CCNCC3)N=C2S1
|
| 215 |
+
O=C1C=C(OCC2=CC=C(F)C=C2)C(C3=CC=C(Br)C=C3)=NN1C
|
| 216 |
+
CN1C(CNC2CCCCC2)=NC3=CC=CN=C31
|
| 217 |
+
COC1=CC=C(C(=O)NCC2=CC=CN=C2C(F)(F)F)C=C1OC
|
| 218 |
+
CC(NC(=O)[C@H1](C)N)C(=O)N[C@@H1](CC1=C[NH1]C=N1)C(=O)O
|
| 219 |
+
C1OC=CC=CC1CN(C(=O)C2=CC=NN2CC3=CC=CC=C3)C4CCCCC4=C
|
| 220 |
+
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3CCCO3)CC2)C(C)=C1C
|
| 221 |
+
COC=CC1=C(/C=C/C(=O)C2=CC3=CC=C(OC)C=C3N=C2)C=CC=C1OC(=O)N(C)C
|
| 222 |
+
CC(C)COC1=CC=CC(N2CCCCC2)=C1
|
| 223 |
+
COC1=CC=C(C=2N=C3SC=CN3C=2/C=N/NC4=NC(C5=CC=C(Cl)C(C)=C5)=CS4)C=C1
|
| 224 |
+
C1CO[C@H1]C(=O)NC(C(=O)OC(C)(C)C)=C1C(=O)N/N=C/C=2C=NNC=2N=C(C3=CC=CC=C3)C4=CC=CC=C4
|
| 225 |
+
O=C(OCC1OC(OC2=CC(O)=C3C(=O)C=C(OC3=C2)C=CC(O)=C(O)C(O)=C)C(O)C(O)C1O)C=CC4=CC=C(O)C=C4
|
| 226 |
+
OC(CC1N(CC2=CC=CC=C2)CC(O)C1C3)CCC(C4=CC=CC=C4)CC3
|
| 227 |
+
CC1=CC=CC=C1C2=CC=C(C(=O)NCC3=CC=CC=C3Cl)O2
|
| 228 |
+
CC(C)C1=CC=C(S(=O)(=O)NC=C(CCCC(=O)O)C2=CC=CC([N+1](=O)[O-1])=C2C)OC=C1
|
| 229 |
+
O=C(O)CCC1CN(C(=O)C(N)C(C)CC)CCC1
|
| 230 |
+
CC(C)CC=1N=C(C2=CC=C(F)C(F)=C2)SC=1C(=O)NCCCCCCNC(=O)C3=CC(Br)=C[NH1]3
|
| 231 |
+
C1C(C)CC(=O)C=C1CC2[C@@](C)[C@@H1](CCC)C2(C)CO
|
| 232 |
+
C=CCOC(=O)C(C#N)=CC(=CC1=C2C=C(Cl)C=C1)C(=O)C(=O)C(C#N)=C(N3CCOCC3)C2C
|
| 233 |
+
C1=CC1=CC=CC2=C(OC)C=C(OC)C(OC)=C2
|
| 234 |
+
CC(=O)N[C@@H1](CSCCCNC(=O)/C=C/C1=CC=C(C2=CC=CC=C2)C=C1)C(=O)N[C@@H1](CC(=O)O)C(N)=O
|
| 235 |
+
C=CC/C=C1/C/C=C/CCCCCCCCCCC(=O)/C=C/CC1=O
|
| 236 |
+
O=C1C=C(OC=2C=C(OC)C=C(O)C1=2)C=CC=CC
|
| 237 |
+
COC1=CC=CC(OCC2=NN=C(SCC(=O)NC3CC3)O2)=C1
|
| 238 |
+
CN(C1=CC=C(C2=CC=C(N3CCN(C)CC3)N=N2)C=C1)C(=O)C4=CC=CC(C(=O)N(C5)CCS(=O)(=O)CC5)=C4
|
| 239 |
+
COC(=O)C=C1C=CC(OC=C2C=C(NC(=O)NCC(C)=NN(C)CCC)CC=C2)=C1
|
| 240 |
+
CCOC(=O)/C=C/C(=O)/C=C/C1=CC=C(F)C=C1
|
| 241 |
+
COC=C1C=C(C=C2C=CC(CN3CCC4=CC=CC=C4C3)=C2)C=C1S(=O)(=O)N(C)C
|
| 242 |
+
CCC1N(C(=O)C2=CC=CN=C2NC3=CC=CC(C(F)(F)F)=C3)CC(C)O1
|
| 243 |
+
CC1=CC=CC=C1C(=O)N(C)C
|
| 244 |
+
OC(C1=CC=C(C(F)(F)F)S1)C(F)(F)F
|
| 245 |
+
CCOC(=O)[C@H1][C@H1]1COC2=CC=C(C)C=C2[C@H1]1N3C(=O)C4=CC=CC=C4S3(=O)=O
|
| 246 |
+
O=CC1=C(C)C(C(=C)C)CC(C=C)(C)C1CC=C(C)C2CC=CC(OO)(C)C2
|
| 247 |
+
O=CN1C(C(=O)N(CCO2)CCCC3=CC(OC)=CC=C3C2)CC1(C)C
|
| 248 |
+
O=COC1C(OC(C)C1C(O)C(O)OC2OC(CO)C(O)C(O)C2OCC)CC(C)CC
|
| 249 |
+
CC(C)C1=CC(C(C)C)=C(OC2=CC=C(/C=N/CC3=CC=C(O)C(O)=C3)C=C2)C(O)=C1
|
| 250 |
+
COC=C1C=C(C(=O)NC2=CC=CC(NC3=NC4=CC=CC=C4C(=O)[NH1]3)=C2)C=C1OC
|
| 251 |
+
O=C(OC=CC=1OC(=CC(=O)C=1C(C2=COC3=CC=C(OC)C=C3C2)=O)CC4=CC=C)C=C4Cl
|
| 252 |
+
COC(=O)C1=CC(Cl)=CC(Cl)=C1OC(=O)C2=CC=CC=C2
|
| 253 |
+
C1=CC(C2=CC=CN=C2)=NC=C1C3=CC=CC=C3CCC
|
| 254 |
+
COC=CC=C(C1=CC(=NO1)C(=O)C2=CC(C3=CC=C(Cl)C(Cl)=C3)=CC=C2)F
|
| 255 |
+
N[C@H1](CO)C(=O)NC1=CC(F)=CC=C1SC2=CC=CC=C2
|
| 256 |
+
CCCCCCC(=O)C1=C(OCC)C(=O)C=C(CCCC)C=C1O
|
| 257 |
+
C1COC=CC=C1[C@H1](NCC(C)(C)C2=CC=C(F)C=C2F)C=O
|
| 258 |
+
CC(C)C(NC(=O)NC[C@H1]1CC[C@H1](C(F)(F)F)CC1)C(=O)NC2=CC=CC=N2
|
| 259 |
+
CC(=O)N1N=C(CC2=CC=CC=C2)CC1C3=CC=CO3
|
| 260 |
+
CC1=CC=C(C(=O)NC(CO)C(O)C2=CC=CC([N+1](=O)[O-1])=C2C)CC=C1
|
| 261 |
+
O=C(O1)C2CC3=C([NH1]C4=CC=CC=C34)C(C5=CCCCC5)N2C1=O
|
| 262 |
+
CCOC(=O)NC1=CC(C(=O)O)=NC=N1
|
| 263 |
+
C=NC[C@H1]NC(=O)CN=C(COC1=CC=C(F)C(C(N)=O)=C1)NCCOC2=CC=CC=C2C(F)F
|
| 264 |
+
CS(=O)(=O)NC1C[C@H1](NC2=NC=C(C(F)(F)F)C(N3C4CCC3COC4)=N2)C1
|
| 265 |
+
O=C(O)C=CC=CCNC=NC(NCCCCC1=CC=CC=C1C)C(C2=CC=CC(C3CC3)=C2)=N
|
| 266 |
+
CC1=CC=C(/C=C(/C#N)C(=O)NC2=CC=C(C#N)C=C2)C=C1
|
| 267 |
+
COC1=CC=C(C(C)=O)C=C1CN2CCO[C@H1](CC3=CC=C(F)C=C3)[C@@H1]2CC4=CC=CC=C4
|
| 268 |
+
C1C=CC=CC1C(=O)NC2=NC3=CC=CN=C3N2CC4=CC=CC(C)=C4C
|
| 269 |
+
COC1=CC=C(CN2CCC(NC(=O)C3=CC=C(F)C=C3)CC2)C=C1OC
|
| 270 |
+
O=C1C2=CC=CC=C2C3=C1C4=CC=C(OC)C(OC)=C4C(=O)N3CC(=O)NC5=CC=C(OC)C(OC)=C5
|
| 271 |
+
CC(C)CCN1C(NC(=O)C2=CC=C(C3=CC=CC(O)=C3)S2)=NC4=CC=CC=C41
|
| 272 |
+
CCCCCNC(=O)NC1=C(CC)C=C(C2=NOC(C(C)C)=N2)C(C)=N1
|
| 273 |
+
O=C(O)C1=CC=CC=C1NS(=O)(=O)C2=CC=CC=C2
|
| 274 |
+
COC=CC(/C=C/C(=O)/C=C/C=C/C=C/C1=CC=CC=C1C)C=COC(=O)C2CCCCC2
|
| 275 |
+
COC=CC=C(CN(CC1=CC=C(NS(=O)(=O)F)C=C1)C2=NC=C(C(C)(C)C)C)N2C=C
|
| 276 |
+
O=C(O)CCCC1=CC=CC=C1
|
| 277 |
+
CN(C[C@@H1](O)CCNC1=NC=C2C(C3=C(C#N)C=NN3C4CCCC4)=NN(C)C2=N1)S(=O)(=O)C5=CC=CC=C5
|
| 278 |
+
COC1=CC(C(=O)NC)=CC(C2=CC=NC=C2)=N1
|
| 279 |
+
CCCN(CCC)C(=O)C1=CC(NC(=O)C2=CC=CN=C2)=CC=C1OC3=CC=CC=C3F
|
| 280 |
+
CCCCCCCCCCCCCCCC(=O)N[C@H1](C(=O)N[C@H1](CC1=CC=C(O)C=C1)C(=O)NCC2=CC=CC=C2F)CCC
|
| 281 |
+
O=C1C2=C(OC=3C=C4OC(CC4=C(OC)C1=3)CC(OC)=C(OC)C2)C=5C=CC=CC=5
|
| 282 |
+
C1C=CC=CC21NC3=C(CN(S(C)(=O)=O)C3N)N2C
|
| 283 |
+
CC(C)CCC1=CC(C(=O)N2CCC[C@H1]2C(=O)NC3=CC=C(N4CCN(C)CC4)C=C3)=NO1
|
| 284 |
+
CCC1C23CC4C(C1)CC(C2)C(C3)(C5CCCCC5)CC4
|
| 285 |
+
COC1=CC=C(S(=O)(=O)NC2=CC=CC(NC(=O)/C=C/C3=CC=CO3)=C2)C=C1OC
|
| 286 |
+
CCOC(=O)[C@]1(C)CCC[C@@]2(C)[C@@H1]3CC[C@@]4(C)C[C@]3(CC[C@@H1]21)[C@@H1]5CN(C6=CC=C(C(=O)O)C=C6)N=C54
|
| 287 |
+
C1NC(C(O)(C2=CC=C(Cl)C=C2)C3=CN=CN3)C=NC4=CC(S(=O)(=O)C5=CC=CC=C5)=CC=C41
|
| 288 |
+
CC=C1C=CC(NC(=O)N2CCC3=CC=CC=C3C2)=C1
|
| 289 |
+
CCOC(=O)C=CC=C(NC(=O)NC1=CC=C2N=C(C3=CC=C(OCC4=CC=CC=C4)C=C3)OC2=C1)C=C
|
| 290 |
+
CC1=CC=C(C2=CC=C(/C=C/C(=O)NCC3=CC=CN=C3Cl)O2)C=C1
|
| 291 |
+
CS(=O)(=O)NC1CN(C(=O)C2=CC=C(Cl)C=C2)C1
|
| 292 |
+
CC(C)C1=CC=CC(C(C)C)=C1NC(=O)CC2=CC=C(C(C)(C)C)C=C2
|
| 293 |
+
CC1=CC=CC=C1N2C(N)=C(C(=O)NCC#N)S/C2=N\C3CCCC3
|
| 294 |
+
CO[C@@H1]1OC(=O)C2=CC(O)=C(O)C(O)=C2C3=C(C=C(O)C(O)=C3O)C(=O)[C@]1C
|
| 295 |
+
COC=CC=C(C1=CC(C2=CC=CC=C2)=NN1CC(=O)NC3=CC(Cl)=CC(Cl)=C3C)N
|
| 296 |
+
COC=C1C=C(S(=O)(=O)N(CC(=O)N/N=C/C2=CC=[N+1](C)C=C2C3)CC=C(OC)C=C3)C=C1
|
| 297 |
+
C1OC=CC(OC)=C1N/C=C(\C)C(=O)C2=CC(OC)=C(OC)C(OC)=C2C
|
| 298 |
+
CN1C[C@H1](C2=CC=CO2)C3=CC=CC(Br)=C3C1=O
|
| 299 |
+
OC1=CC(=CC2=C1C3=NC(=NC=C3C(C2)CCCCC)C)SC
|
| 300 |
+
CC1=CC=C(S(=O)(=O)NC2=CC=CC=C2[N+1](=O)[O-1])C=C1
|
| 301 |
+
COC1=CC=CC=C1C2=NC(CSC(C)C(=O)NC3=CC=CC=C3)=CO2
|
| 302 |
+
CNC(NC1=C(Cl)C=CC(CNC(=O)COC2=CC=CC=C2)=C1)Cl
|
| 303 |
+
COC1=CC=CC(/C=N/C2=CC(C3=CC=CC=C3)=CC=C2O)=C1OC
|
| 304 |
+
N#C/C(=C\C1=CC=CC=C1)SCC2=CC=C3C=CC=CC3=C2
|
| 305 |
+
COC1=CC=C2C3=CC=NC(C)=C3N(CC(F)(F)F)C2=C1
|
| 306 |
+
CC(C)C1=CC=CC(C(C)C)=C1NC(=O)NCCC2=CC=C(NS(=O)(=O)C3=CC=C(F)C=C3)C(=O)N2
|
| 307 |
+
CC=C1C=CC(C(=O)N2C=NC3=C(C4=CC=CC=C4S3)S2)=C1
|
| 308 |
+
COC1=CC=CC=C1C=CC(C(=O)NC2=CC=C3C(=C2)C(=O)OC3C4=CC=C(C=5C=NN(C6CCCC6)C=5)C=C4)=CC=CO
|
| 309 |
+
N[C@H1](C(=O)O)[C@@H1](O)C(=O)O
|
| 310 |
+
COC=C1C=C(OC(=O)NCCC2=CC=NC=C2)C=C1
|
| 311 |
+
COC1=CC(/C=C2\SC(=O)N(CC(=O)NCC3=CC=CO3)C2=O)=CC=C1O
|
| 312 |
+
CC(=O)N[C@@H1](CC1=C[NH1]C=N1)C(=O)N[C@@H1](CC2=CC=CC=C2)C(=O)N[C@@H1](CC(C)C)C(=O)N3CCC[C@H1]3C(=O)N[C@H1](C(=O)N4CCC[C@H1]4C(N)=O)CCC
|
| 313 |
+
CC(C)C1=CC=C(C2=NOC(=O)[NH1]2)C=C1
|
| 314 |
+
O=C(O1)C2C3C=CC(CC4C(CC5=CCNC(=C5)N)CC(CC6=CC=CC(=C6)CCCC7C)CC(CNC)CCC7C4C3(O)C1)OCCCCC2
|
| 315 |
+
CC=C1C(C(=O)N2CCC(S(=O)(=O)N3CCOCC3)CC2)=CC=C1F
|
| 316 |
+
CCOC(=O)C(C)(C(=O)OC1)[C@@H1]2C3=CC=CC=C3C=C2CN1C(=O)COC(=O)C4=CC=CN=C4
|
| 317 |
+
COC=C1C=C(CNC(CNCC(C)(C)CN(C)CC2)=CC=CC=C2C)N1
|
| 318 |
+
CC=1ON=C(C2=CC=CC=C2)C=1C(=O)N3CCC(NC(=O)C4CCC4)CC3
|
| 319 |
+
CCOC(=O)C(C)(C)NC1=NC(NCC2=CC=CC=C2)=NC(N3CCOCC3)=N1
|
| 320 |
+
COC1=CC(CNCCCN2CCCCC2)=CC3=C1OCO3
|
| 321 |
+
CS(=O)(=O)NCC1C=C(C2=CC=CC=C2)C(=O)C1
|
| 322 |
+
CCOC(=O)C=C(CN1CC(C(=O)O)C1)N(C)C2=CC(OC)=C(OC)C=C2
|
| 323 |
+
CCCCCCCCCCCCNC(=O)OC(C1=CC=CC=C1)C(C2=CC=CC=C2)=C
|
| 324 |
+
COC1=CC=CC=C1OCCN2C=CC(N3C=CC4=CC(OC)=CC=C43)=NC5=C(OC)N=C(N)N=C52
|
| 325 |
+
CCCCCNC(=O)N(CC(=O)N[C@@H1](CC1=CC=C(C2=CC=CN=C2)C=C1)C(C)C)CCC3=CC=CC=C3
|
| 326 |
+
CCCCCC(=O)N[C@H1](C(=O)NO)C(C)C
|
| 327 |
+
CC1=CC=C(NC(=O)C2=CC(S(=O)(=O)N3CCN(C)CC3)=CC=C2Cl)C=C1C
|
| 328 |
+
O=C1NC(C(=O)NC2=CC=CC=C12)CC(=O)NCCC(=O)N3C=C4N(C3=O)CCCN(C)CC4
|
| 329 |
+
CC1=CC=CC(C(=O)C2=CC(Cl)=CN=C2OC3=CC=CC=C3Cl)=C1
|
| 330 |
+
COC1=CC=C(N2C=C(C3=NN=C(SCC(=O)C4=CC=CC=C4OC)O3)N=N2)C=C1
|
| 331 |
+
O=C1C2=C(O)C=C(C(O3)=C2C(=O)C=C(O)C3=C(O)C=C1)COC4OC(C)C(O)C(O)C4
|
| 332 |
+
CNC[C@@H1]1OCS/C1=N\N=C\C2=CC=CC=C2OCC3=CC=CC=C3
|
| 333 |
+
CC=1[NH1]C2=CC=CC=C2C=1C(=O)C3=CC=C(C#N)C=C3
|
| 334 |
+
COC1=CC=C(C(C)=O)C=C1CN2CCOC3=CC=CC=C32
|
| 335 |
+
O=CNCC1[C@](CN(C2=CC=C(C(F)(F)F)C=N2)[C@H1]1C3=CC=CC=C3C)CF
|
| 336 |
+
COC1=CC=C(C2=NN=C3SC(NCCC4=CC=C(F)C=C4)=NN23)C=C1OC
|
| 337 |
+
COC=C1C=CC(NC(=O)COC(=O)C2=C(OC)C=CC=C2)OC1
|
| 338 |
+
C=C[C@@](O)(C(N)=O)C=CC=C(O[C@@H1]1O[C@H1](COC(C)=O)[C@@H1](O)[C@H1](O)[C@H1]1OC)C
|
| 339 |
+
O=CNC1(C=C(C)C)C=C(C=C2CC(C(=CC(O)C=CCCC1)C)CCC2CC)CC
|
| 340 |
+
O=C1NC(C(=O)N1CC2=CC=C3OCOC3=C2C)C(=O)N4CC=5[NH1]C6=CC=CC=C6C=5CC4
|
| 341 |
+
CC(C)(C)OC(=O)N(C1=C(F)C(F)=C(F)C(F)=C1C=O)CC
|
| 342 |
+
O=C1C=C(OC2=C1C(O)=C(O)C(O)=C2C(C3=CC=4C=CC(OC)=CC=4NC3=O)C(O)=NCC=5C=CC=C(C=5)CCCCC)O
|
| 343 |
+
COC(=O)C1=CC=CC(N(CC2=CC(Cl)=C3C=CC=CC3=N2)C4=CC=CC(OC5=CC=CC=C5)=C4)=C1
|
| 344 |
+
CC(C)C(C#N)NC(=O)C=1C=C(C2=CC=CC=C2)SC=1C(F)(F)F
|
| 345 |
+
CC=CC=CC(CN(C(=O)C1=CC=C([N+1](=O)[O-1])C=C1)C2=CC=CC=C2[N+1]=O)[O-1]
|
| 346 |
+
COC1=CC=CC=C1C(=O)NC2=CC=CC(OC3=CC=C4C=CC=CC4=N3)=C2
|
| 347 |
+
CCOC(=O)C=C1C=C(CN2C(=O)C(C)=NC3=CC(NS(=O)(=O)C4=CC=C(C)C=C4)=CC=C32)C=C1
|
| 348 |
+
N#C/C(=C\C1=CC=C([N+1](=O)[O-1])C=C1)C(=O)NCC2=CC=C(F)C=C2
|
| 349 |
+
CC1=CC=C(N2N=NC=C2C(=O)NCC3=CC=CO3)C=C1C
|
| 350 |
+
C=CCOC1=C(Cl)C=C(Cl)C=C1C(=O)N2CCN(CCOC)CC2
|
| 351 |
+
COC1=CC=C(C(=O)O)C(S(=O)(=O)N2CCCC2)=C1
|
| 352 |
+
COC1=CC=CC=C1N2CCN(C(=O)C3=CC=C4C=CC=CC4=C3)CC2
|
| 353 |
+
CCN(CC1)C=CC=C(C2=C(C3=NCCN3)C4=C(O)C=C(OCCCC5=CC=CC=C5)C=C4OC2)OC=C1
|
| 354 |
+
CC(C)COC(=O)N1CCC2=C([NH1]C3=CC=C(F)C=C23)C1C
|
| 355 |
+
CC(=O)N(CC(=O)N[C@@H1](CCCCN)C(=O)N(CCC(=O)N[C@H1](C(=O)O)[C@@H1](C)O[C@@H1])CCCC[C@@H1]C)O
|
| 356 |
+
CC(=O)N1C=CC(C)=C(NC(=O)COC2=CC=C(C(=O)NO)C=C2C)C1C
|
| 357 |
+
CC1[C@](COC(N)=O)NC(=O)C2=C1C(=O)N(CC(=O)NC3CCCCCC3)C2=O
|
| 358 |
+
COC1=CC=C2C(=C1)CCC2NC(=O)COC3=CC=CC=4[NH1]N=NC3=4
|
| 359 |
+
CC1=CC=C(NC2=NC=CC(S(=O)(=O)C3=CC=CC4=CC=CC=C34)=N2)C=C1C
|
| 360 |
+
CCN(CC)CCNC=C1C=CC=2C(=NN(C)C#N)C(=O)N(C(C)C)C(=O)C1=2
|
| 361 |
+
CC1=CC(NC2=NC=NC3=CC(OCCCN4CCOCC4)=C(F)C=C23)=CC=N1
|
| 362 |
+
O=C(O)CCC(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(N)CC1=CNC=2C=CC=CC=21)CC3=CN=CN3)C=4C=CC=C5C=4)C(C)CC(=O)NC(C(=O)NCC(=O)N(C)CC(=O)NC(C(=O)NC(C(=O)NC5(C(=O)N(C)C(C(=O)NC(C(=O)NC=CC)COC)CCS(=O)NC)CC)(C)CCC(C)CCC)(C)CCCC)C
|
| 363 |
+
C=CCOC=CC=C1C=C(C)S2C=C(C3=CC=C(OC)C(OC)=C3)C(CC)=NN12
|
| 364 |
+
COC=CC=C(C(=O)OC1=CC=C(C(C)C)C=C1C)CN2CCN(C3=CC=NC=C3)CC2
|
| 365 |
+
C1C(C)(C)OC(=O)NCCCCCNC(=O)COC=CC=C(C(=O)O)C1CN(C(=O)[C@H1]2CNCC(=O)N2C3=CC=C(CCCOC4=C(F)C=CC(F)=C4F)C=C3)C5CC5=C
|
| 366 |
+
CC1=CC=CC(C)=C1NC(=O)NCC2=CC=C(CN3CCCC3)C=C2
|
| 367 |
+
C1C=CC=CC1C=C2C(N[C@@H1]3CCCC[C@@H1]3N)=C4C=NC(NCC5CCOCC5)=NN24
|
| 368 |
+
O=CC=C(C)CCC=C(C)C
|
| 369 |
+
O/N=C(/C1=CC=CN=C1OC2=CC=C(C(F)(F)F)C=C2)N3CCOCC3
|
| 370 |
+
C1CCCCC1C(=O)NC(CC2=C[NH1]C=N2)C(=O)NC3=CC=C(C(=O)O)C=C3
|
| 371 |
+
COC1=CC=C(C2=NN(C3=CC=C(OC4=CC=CC=C4)C=C3)C(C5=CC=CC=C5)C2)C=C1
|
| 372 |
+
CCC1CC(C(O2)CCCC(N)(C3=NC=NC=4[NH1]C=CC3=4)CC2)CC1
|
| 373 |
+
C1OC=CC=C(C(CNC(=O)COC(=O)CNC(=O)CC2=CC=CC=C2C)=O)C=C1
|
| 374 |
+
CN(CC1=CC=C([N+1](=O)[O-1])C([N+1](=O)[O-1])=C1)CS(=O)(=O)C2=CC([N+1](=O)[O-1])=CC([N+1](=O)[O-1])=C2
|
| 375 |
+
CCC1CC=C2C3=CN=CC(NCCOCCO)=C3C=C(Cl)C2=C1
|
| 376 |
+
CC/C=C/[C@H1]C[C@@H1](C)/C(O)=C1/C(=O)O[C@H1](C)[C@@H1]1/C=C/[C@@H1](O)C[C@@H1](O)C(=C)CC/C=C\C2/C=C\C/C=C\C=C\C=C\[C@H1]2O[C@H1]3CC[C@H1](N(C)C)[C@@H1](C)O3
|
| 377 |
+
CC[N+1]1=CC=CC=C1/C=C/C=C2C=C(OC3C=CN([C@@H1]4O[C@H1](COS(N)(=O)=O)[C@@H1](O)[C@H1](O)[C@H1]4)ON=N3)C=C2
|
| 378 |
+
O=C(O)C=C1C=C(NC2=NC(NC3CCCC3)=NC(NC4=CC=C(OCCN5CCCCC5)C=C4)=N2)S1
|
| 379 |
+
COC=C1C=C(CCNC(=O)CNC(=O)COC2=CC=C(S(=O)(=O)N3CCCCC3)C=C2C)OC=C1
|
| 380 |
+
CCOC(=O)C(=CC1=CC=C(O)C=C1)C(Cl)(Cl)Cl
|
| 381 |
+
O=C1C=C(C2=CC=CC=C2)OC3=CC(N4CCOCC4)=CC(OC5=CC=CC=C5)=C31
|
| 382 |
+
CC1=CC=CC(C(=O)N2CCCN(CC3=CC=C4C(=C3)OCO4)CC2)=N1
|
| 383 |
+
O=P(O)(O)C1OC(NC2=NC=C(Cl)C(NC3=CC=NC(C4=CC=CC=C4)=N3)=N2)C1
|
| 384 |
+
CS(=O)(=O)C1=CC=C(C=CC=C2N=CN=C(N3CCC(N4CCCCC4)CC3)C2=C1)C=C
|
| 385 |
+
O=C1C=CC=C2N1CC3CN(C(=O)C4=CC=CC(Cl)=C4)CC2C3
|
| 386 |
+
CS(=O)(=O)N1N=C(C2=CC=CC=C2)CC1C3=CC=CC=C3
|
| 387 |
+
CC(C)(C)OC(=O)NC1=CC(C(F)(F)F)=CC=C1C(=O)O
|
| 388 |
+
N/C=C1\C(=O)C2=CC(F)=CC=C2NC(=O)C1CC3=CC=CC=C3F
|
| 389 |
+
C1OC=CC=C1CNS(=O)(=O)C2=C(C)N=CSC(N)=NN2
|
| 390 |
+
O1C=NC(NCC2=CC=CC=C2C(F)(F)C3=CC=CN=C3)=NC(N[C@@H1]4CCCNC4)=N1
|
| 391 |
+
C1OC2=CC=CC(=C2)C(=O)N1[C@H1](C)[C@H1](C3C=CC=C(NC(=O)[C@H1]4CCCN4S(=O)(=O)C5=CC=C(F)C=C5C)C3C)C=O
|
| 392 |
+
C1C=CC=CC1C(C)N2C(=O)CC3(CCCC3)CC2=O
|
| 393 |
+
COC=CC=C1C(=NC2=CC=CC=C2N1CC3=CC=CC=C3)C=C(C)CC=O
|
| 394 |
+
CC=CC=CC(NC(=O)C=CC(N(C)S(C)=O)=O)F
|
| 395 |
+
C1OC2=CC=C(C=C2OC3)OC4=NC=NC(N5CCOCC5)=C4C=C3N(C(=O)NCC6=CC=CC=C6)CC1
|
| 396 |
+
O=CN1C(=O)N(C2=CC=CC=C2)C(=O)N1
|
| 397 |
+
O=C1NC(=S)S/C1=C\C2=CC(C=3C=C[NH1]C=3)=CC=C2OCC4=CC=CC=C4
|
| 398 |
+
C12C(C)(C)OC(=O)NCCNC=CC2(NC=NC=C(Cl)C1(NC3=CC=CC=C3S(=O)(=O)NC(C)C=N)N)CC
|
| 399 |
+
CC1=CC=C(N2N=CC=C2C3CCN(CCC4=CC=CC=C4)CC3)N=C1
|
| 400 |
+
CCOC(=O)C1=CSC=C1NS(=O)(=O)C2=CC(C(=O)NC)=CC(C(F)(F)F)=C2
|
| 401 |
+
CC(C)(C)OC(=O)N1CCC(N2CCC(OC3=CC=C(F)C=C3F)CC2)CC1
|
| 402 |
+
COC1=CC=CC=C1N2CCN(CC3=CC=CC=C3OC)CC2
|
| 403 |
+
CC1=CC=CC=2N=C(C3=CC=CC=C3Cl)OC1=2
|
| 404 |
+
CC1=CC=C(NC(=O)NC2=CC=C(F)C(Cl)=C2)C=C1CNC(=O)C3=CC(C(F)(F)F)=CC=C3F
|
| 405 |
+
CCC1CCCCN1C2=NC=CC(NC[C@H1](O)C3=CC=CC=C3)=N2
|
| 406 |
+
COC(=O)C1=CC(NC(=O)C2=C(Cl)C=CC=C2Cl)=CC=C1OC3CCOC3
|
| 407 |
+
COC1=CC=CC=C1CNC2=[N+1](CC3=CC(C(=O)[O-1])=CC=C3OC4=CC=C(OC(F)(F)F)C=C42)CC=CC=C
|
| 408 |
+
CCCCCCCC1[N+1]=C(C)C2=CN=C3C=CC=CC3=C21
|
| 409 |
+
CCCCCSC(=O)N[C@H1]C(=O)N[C@@H1](CO)C(=O)N[C@@H1](CCCNC(=N)N)C(=O)N[C@@H1](CC(C)C)C(=O)N[C@@H1](CCCNC(=N)N)C(=O)N[C@H1](C(=O)N[C@@H1](CO)C(N)=O)C(C)C[C@@H1](C)O
|
| 410 |
+
CC(N1C2=CC(F)=CC(F)=C2F)CCN(C(=O)C3=CC=C(C4CC4)N=C3)CC1
|
| 411 |
+
COC1=CC=CC=C1CNC(=O)CN2C(=O)OC3=CC(S(=O)(=O)N4CCCC4)=CC=C32
|
| 412 |
+
C1COC(=O)C(=O)C=C(CC1)C(C(=O)OC=2)SC(C)=C(C#N)C=2C=O
|
| 413 |
+
O=C1C2=CC=CC=C2OCC1C3=CC(F)=CC(NS(=O)(=O)N4CCOCC4)=C3
|
| 414 |
+
COC1=CC=CC=C1NCCN(CCNC(=O)C2=CC=CC(OC3=CC=CC=C3)=C2C)C
|
| 415 |
+
C1C2=CC=CC=C2C=CC3=C1C4=NC5=CC=CC=C5N=C4N3C6=CC=CC(C(=O)O)=C6C=C
|
| 416 |
+
COC1=CC=C(S(=O)(=O)N(C)C2=CC=CC=C2)C=C1C(=O)O
|
| 417 |
+
CC1=CC(CN(CC2=CC=CC=C2)CC3=CC=CN=C3)=C4N=CC=NC4=C1
|
| 418 |
+
N#C[C@@H1]1CCCN1C(=O)CNC(=O)OC2=CC=C(Cl)C=C2F
|
| 419 |
+
CCN(CC)C1CN(C2=CC=C(N3C[C@H1](CN4C=CN=C4)S[C@H1](C)C3)C=N2)C1
|
| 420 |
+
CC1=CC=CC=C1NC(=O)C=C2C=C(S(=O)(=O)N(C)CC(=O)N3CCC(C(=O)N4CCCCCC4)CC3)C=C2
|
| 421 |
+
O=COCC1CC(C)C(C2)CCCC3(C)C(CCC3C2(C)C1CC4=COC=C4C)COCCC
|
| 422 |
+
COC=CC=C(NS(=O)(=O)C=CC=COC(=O)NC1=CC(C(N)=O)=CC2=NSN=C12)C=C
|
| 423 |
+
OC[C@@H1]OC1(NC(CC2=CC=CC=C2)=NC3=CC(Cl)=CC=C31)N[C@H1](O)[C@@H1]O
|
| 424 |
+
O=C(OC12C3=CCC(OC(=O)C)C=C(O)CC(C4=CC=CC=C4)C(OC(=O)C)C3C1=C2OC)CC
|
| 425 |
+
CCCCCCCCCCCCCCOC1=CC=CC(OP(=O)(O)OC[C@H1]2O[C@@H1](N3C=NC4=C(N)N=CN=C43)[C@@H1](O)[C@@H1]2O)=C1
|
| 426 |
+
CC(C)(C)C1=CC=C(N2N=CC(C=3N=N[NH1]N=3)=C2C4=CC=CC=C4)C=C1
|
| 427 |
+
COC(=O)C=CC=CNC(=O)[C@H1](CC(C)C)NC(=O)CN1C(=O)NC(C2=CC=CC=C2)(C3=CC=CC=C3)C1=O
|
| 428 |
+
CC1=CC=CC=C1C(C(=O)N2CCC(NCCCC3=CC=CC=C3)CC2N4)CCCCC4
|
| 429 |
+
CCCCCCCCCCCCCCCC(=O)OCC(CC(=O)O)[N+1](=O)[O-1]
|
| 430 |
+
CC1=CC=C(NC(=O)C2=CC=C3C(=C2)N=NN3CC4=CC=CC=C4OC(F)(F)F)C=C1
|
| 431 |
+
C1CCCC=C(SC=NC(SCC(=O)NC2CCCC2C)=NC(C3=CC=CO3)=C)C1
|
| 432 |
+
CCCCCCNCC1(C(=O)O)NC(COC2=CC=CC=C2)=NC3=CC=CN=C31
|
| 433 |
+
COC1=CC=CC=C1NC(=O)CSC2=NC3=CC(C(=O)N(C)C)=CC=C3[NH1]2
|
| 434 |
+
CC(C)CC(/N=C(\S)NC1=CC=C(Cl)C(Cl)=C1)C2=CC=CC=C2
|
| 435 |
+
O=C(O)CC=1C=NN(C(=O)C)C=1
|
| 436 |
+
COC1=CC=C(/C(C)=N/C2=CC=C(N3N=C(C)C=C3C)C=C2)C=C1
|
| 437 |
+
COC1=CC(C(=O)N2CCN(C3=CC=NC=C3F)CC2)=CC=C1N4C=NC(C)=C4
|
| 438 |
+
C1C=CC=C(C2=CC=CC=C2CN3CC4C(CC3)C=5C(=NN(C)C=5C(F)(F)F)CC4N)C1
|
| 439 |
+
CCOC(=O)CC=C1C=C([C@@H1]2[C@@H1]3C(=O)N(C4CC4)C(=O)[C@H1]3C(=O)N2C5=CC=CC=C5)C=C1
|
| 440 |
+
COC1=CC=CC=C1NC(=O)[C@H1]2O[C@@H1](C=3C=COC=3)N[C@H1]2C4=CC=C(Cl)C=C4
|
| 441 |
+
COC(=O)C=C(C1=CC=CC=C1)C2=CC(Cl)=CC=C2OC=O
|
| 442 |
+
C1C=CC=C(NC(=O)COC(=O)/C=C/C2=CC=CS2C)C1
|
| 443 |
+
CC1=CC=CC(C)=C1N(C)C(=O)C2CCN(C(=O)N(C)CCC)CC2
|
| 444 |
+
C1OC=CC=C1NC(=O)CSC=NC2=CC(NC(=O)C3=CC=CC=C3)=CC=C2C(=O)[NH1]
|
| 445 |
+
COC1=CC(C(=O)NC2=CC=C(NC(C)=O)C=C2)=CC=C1C(=O)NC3CCN(CC4=CC=C(C#N)C=C4)CC3
|
| 446 |
+
O=C1C=COC(O)=C1C(C2=CC=CC(NS(=O)(=O)C3=CC=C(OC)C=C3)=C2)CC
|
| 447 |
+
C1(=C(C=C2C(=C1)OC(=C(C2=O)O)C3=CC=C(C(=C3)OO)CC4=C(C)C(C(=C4)O)O)OO[C@H1]5[C@@H1][C@H1]([C@H1]([C@@H1](O5)CO)O)O)O
|
| 448 |
+
CC(=O)NC(C1=CC=CS1)CCN(CCCCC2=CC(C(C)C)=NN2C)CCC
|
| 449 |
+
COC1=CC(/C=C\C2=CC(O)=C(O)C(O)=C2N)=CC=C1OC[C@@H1](O)[C@H1](O)[C@H1]CO
|
| 450 |
+
C1OC=CC=C(NC(=O)C(=O)C2=C[NH1]C3=CC=C(OC)C=C23)C1OC
|
| 451 |
+
O=C1C=CC=CN1CCC2N(C(=O)CN3N=C(C=C3C)CC(C)(C)C)CC2
|
| 452 |
+
CC=C1C=CC=2N=C(O)N(CC(=O)N3CCCC3)C(=O)C1=2
|
| 453 |
+
CN(C/C=C/C1=CC=C(C2CCCCC2)C=C1)C3=NC4=C(C=NN4C5=CC=C(F)C=C5)C(=O)[NH1]3
|
| 454 |
+
C1COC=CC=C1S(=O)(=O)NC=C(C2=CC=C(OCC(=O)O)C=C2)C=N
|
| 455 |
+
COC1=CC=C(/C=C/C(=O)N/N=C/C2=CC=C(O)C(O)=C2)C(OC)=C1
|
| 456 |
+
C1OC=CC=C(CN2C(CN3CCN(C(C)C)CC3)=NC(C(F)(F)F)=C2C#N)C1
|
| 457 |
+
CCN(CC)C1=CC=C(C(F)(F)F)C=C1NC(=O)C=CC2=C(N3CCN(C)CC3)C(NC4=NC=CC(C5=CC=CN=C5)=N4)=C2
|
| 458 |
+
COC1=CC=C(CCN(C(=O)COC2=CC=C(Cl)C=C2)CC)C=C1OC
|
| 459 |
+
CC(=N)NC1=CC=CC=C1
|
| 460 |
+
CCCN(CC1CC1)C2=CC=C(F)C=C2NC3=NC=NC4=CN=C(N5CCCC5)N=C34
|
| 461 |
+
C=CCOC1=C(Br)C=C(C(=O)O)C=C1S(=O)(=O)O
|
| 462 |
+
COC1=CC=CC=C1C(=O)NCC(CC2=CC=C(O)C=C2)N3CCCCC3
|
| 463 |
+
CCOC(=O)C=1[NH1]C2=CC(Cl)=CC=C2C=1C(NC3=CC=CC(Cl)=C3)=N
|
| 464 |
+
CC[C@@]1(O)O[C@H1](COCC(=O)O)[C@@H1]1[C@@H1]C=C[C@H1]2OC(=O)C=CC2
|
| 465 |
+
C=CCSC(=O)NC1=CC=C(C(=O)NC2=CC=C(NC(=O)CCCCCC(=O)O)C=C2)C=C1
|
| 466 |
+
COC1=CC=CC=C1C(=O)N2CCC[C@H1]2C3=NN=CN3C
|
| 467 |
+
COC1=CC=C(/C=C2\OC(=O)C(C3=CC=C(O)C(O)=C3)=C2C4=CC=CC=C4F)C=C1
|
| 468 |
+
CC=C1C=CC(C(=O)NC2=CC(C(F)(F)F)=CC=C2N3CCCC3)=N1
|
| 469 |
+
COC1=CC=C(C(=O)NC2=CC=C(C)C=C2)C=C1NC(=O)CC3=CC=C(C)N=C3
|
| 470 |
+
CC(C)C=CC=CCNC=1C=C(C(=O)N2CCNCC2)N(C3=CC=C(N4CCOCC4)C=C3)N=1
|
| 471 |
+
OC1=CC(Cl)=CC(C2=CC=C(F)C=C2F)=C1O
|
| 472 |
+
C1C(=O)N[C@@H1](C)C=CC=C1N[C@@H1](C)C(=O)N[C@H1](C(=O)NC(C)(C)C)C(C)CC=C
|
| 473 |
+
C[Si](C)(C)CC(CC(F)C(C)(C)O)CCC1OC1(C)C
|
| 474 |
+
CCN(CC)C(=O)C(C#N)=NN1C(C2=CC=C(C)C=C2)=CN=C1S
|
| 475 |
+
O=C(O)/C=C/C1=CC=CC=C1CC2=CC=CC=C2
|
| 476 |
+
COC1=CC=CC=C1C(=O)NC2=CC=C3C(=C2)N(CC(=O)NC4CCCC4)C(=O)C5=CC=CC=C5[S+1]3[O-1]
|
| 477 |
+
COC1=CC2=C(C=C1OS(N)(=O)=O)CC[C@@H1]3[C@@H1]2CC[C@]4(C)[C@@H1](C(C)=O)CC[C@@H1]34
|
| 478 |
+
CC(=O)N(O)/C(=N/C=C(N)N)NC(=O)[C@@H1]1OC(OP(=O)(O)O)[C@@H1](O)C(O)[C@@H1]1O
|
| 479 |
+
C1OC(=O)C=CC=CC1CNC(=O)CC2=CN=C3C=CC(N4CCC(C)CC4)=NN23
|
| 480 |
+
COC=C1C=C([C@H1][C@H1](O2)[C@H1](C3=CC(C)=CC(C)=C3)N(C(=O)C(C)OC4=CC=CC=C4)C2)C=C1OC
|
| 481 |
+
COC=CC=C(C=C(C1=CC=C(NS(C)(=O)=O)C=C1)CCCC(F)F)F
|
| 482 |
+
COC1=CC=CC2=C1C(=O)C3=C(C2)NC(N)=C(C#N)C3C=C(C(=O)N(C)C(=O)N(C)C=O)NC
|
| 483 |
+
O=COCCC1C(O2)(CCCCC3(OCOC(C)C(OC4OC(C)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4OC)(O)COC6OC(C)C(O)C(O)C6)OCCC23CC7(O)CCCO)C(=O)CC17CC
|
| 484 |
+
C1OC=CC=C1/C=C2\S/C(=N\NC(=O)C3=CC=CN=C3)N(C4=CC=C(F)C=C4)C2=O
|
| 485 |
+
COC(=O)C1=CC(C2=CC=C(OCF)C=N2)=CC(C(=O)OC)=C1
|
| 486 |
+
CC1=CC=CC=C1C(=O)O[C@@H1]2CC[C@@]3(O)[C@H1]4CC5=CC=C(O)C6=C5[C@@]3(CCN4CC7CC7)[C@H1]2O6
|
| 487 |
+
O=C1C2=CC=CC=C2N=C(SCC3=CC=C([N+1](=O)[O-1])C=C3)N1CC4=CC=CC=C4
|
| 488 |
+
CCCCCCCN(CCC1=CC=CC=C1)CC2=CC=C(OCC3=CC=CC(F)=C3)C=C2
|
| 489 |
+
CC1=CC=CC=C1NC(=O)C2=CC(S(=O)(=O)N3CCN(C4=CC=CC=C4)CC3)=CC=C2F
|
| 490 |
+
COC1=CC=CC(C(=O)NC2=NC=CC=C2C)=C1
|
| 491 |
+
CCCCC1(C(=O)NCC(CO)CC)N(C2=CC=C(F)C=C2)CC1
|
| 492 |
+
CC(C)CC1NCC(=O)N(CCCCCCNS(=O)(=O)C2=CC=CC3=CC=CC=C23)C1CCC4=CC=C(Cl)C(Cl)=C4
|
| 493 |
+
CCCN(C(=O)[C@H1]1CNCCN1S(=O)(=O)C2=CC=C3C(=C2)OCCO3)C4CCS(=O)(=O)C4
|
| 494 |
+
COC=C1C=C(N/C=C2\C(=N)NN=C2C3=CC(Cl)=C(OC)C=C3O)CC=C1
|
| 495 |
+
CO[C@](C1=CC=CC=C1)CC(=O)C(CC2=CC=C(C3=CC=C(F)C=C3)C=C2)C=O
|
| 496 |
+
CC1=CC=C(C(=O)N(C)[C@@H1](C)C2=CC=C(NC(=N)NCC3=CC=CC=C3C#N)C=C2Cl)C1
|
| 497 |
+
CN(C(=O)C1=CC=CC(N2N=CC(C(=O)O)=C2C3=NC4=CC=CC=C4S3)=C1)C5=CC=NC=C5
|
| 498 |
+
CC(C)CC=NC1=C(C(C(=O)N[C@@H1]2CCN(C#N)C2)=N)CCC3=CC=CC=C31
|
| 499 |
+
O=C(NC=CC=C1C=C(C2=CN3C=CC=CC3=N2)N=C(SCC4=CC=C([N+1](=O)[O-1])C=C4)[NH1]C=C1C5C)CN(CC6=CC=CC(OC7=CC=CC=C7)=C6)CC5
|
| 500 |
+
CCOC(=O)/C=C1\SC(NC2=CC=CC3=CC=CN=C23)=NC1=O
|
| 501 |
+
CC=C1C=C(NC(=O)COC(=O)CN2C(=O)OC3=CC=CC=C32)C=C1
|
| 502 |
+
C=NC(=O)CNC(=O)C=NN(C1=CC=C(F)C=C1)C(=O)CC
|
| 503 |
+
O=C(O)CCCN=CC(NCC1=CC=CC=C1)=CC2=CN=CC=C2
|
| 504 |
+
C=CC=1SC(N)=NC=1C=2C(=CNC=2C)CC(NC(=N)N)CC
|
| 505 |
+
CC1=CC=CC=C1N2N=CC3=C2CC(C)(C)CC3(C)C
|
| 506 |
+
CCN(CC)CC(=O)NCC1=C(NC2=CC=C([N+1](=O)[O-1])C=C2OC[NH1])N1
|
| 507 |
+
COC1=CC=CC=C1/C=C/C(=O)N[C@H1]2C[C@H1]2C3=CC(C(=O)C4=CC=CC=C4)=CC(C(=O)OC)=C3
|
| 508 |
+
O=C(O)C1CCCN(S(=O)(=O)C2=CN=C(C3CC3)C=C2F)C1
|
| 509 |
+
CCCCCCCCCC1C(N)C(=O)NC(C2=CC=CC=C2)C(C(C)=O)CC1=O
|
| 510 |
+
COC(=O)C1=CC=C(NC(=O)CC2C(=O)N(C3=CC=CC=C3)C(=O)N2C4=CC=C(Cl)C=C4)C=C1
|
| 511 |
+
N#C[C@H1]CCN(C1CCN(C(=O)C2CC2)CC1)CC
|
| 512 |
+
O=C1NC(C(=O)N1CC2=CC=C3OCOC3=C2)CC(=O)N4CC5=CC(OC)=C(OC)C=C5CC4
|
| 513 |
+
CC1=CC2=CC(=C1)N=C(NC3=CC=CC(Cl)=C3)CS2(=O)=O
|
| 514 |
+
N1[C@H1]CN(C(=O)N2CCC3=CC=CC=C32)[C@@H1]CCC[C@H1]1
|
| 515 |
+
CC(=O)N(C(=O)NC1=CC=C(F)C(Cl)=C1)C2=NC=CC=C2C(F)(F)F
|
| 516 |
+
COC1=CC=CC(=C1)CC(C2=CC=CS2)CC(=O)NCC3=CC=CC=C3
|
| 517 |
+
CC(C1)CC2=CC=C(N3CCCC3)C=C2[C@H1](F)CCCN1
|
| 518 |
+
CON[C@H1](C)C1=CC=CC(C2=CC3=C([NH1]2)C4(CCOCC4)CNC3=O)=C1
|
| 519 |
+
CC=C1C=C(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2C4=CC=C(F)C=C4)C=C1
|
| 520 |
+
O=[N+1]([O-1])C=CN=C(NC1CC(C(=NN(C2CC2)C3CC3)C)C1C)N
|
| 521 |
+
CC1CCCN(C2=CC=C(C3=NC=NC=4[NH1]C=CC3=4)C(OC)=C2F)C1
|
| 522 |
+
NS(=O)(=O)C1=CC=C(C2=CC(NCC3=NC4=CC=CC=C4N3C)=N[NH1]2)C=C1
|
| 523 |
+
CC(=O)N(C(=O)O)CC(C(N)=O)C1=CC=CO1
|
| 524 |
+
CC(C)C=NN=C(CN(CC1=CC=C2N=CC=CC2=C1)S(=O)(=O)C3=CC=C(F)C(F)=C3)O
|
| 525 |
+
CC=C1C=C([C@H1]C2N(C3=NC(C4CC4)=NC5=C3N=C6N5CCCC6)CCO2)C=C1
|
| 526 |
+
O=C(OCC12C(=CC3OC(=O)C(=C)C3C1)C(OC(=O)CCC4)C(=C)CCCC24C)COCCCC
|
| 527 |
+
CS(=O)(=O)NCCN(C1=NC(N[C@H1]2CCCCO2)=NC3=CC=CC=C13)C
|
| 528 |
+
CC1=CC=C(C(=O)NC2=CC=C(OC(=O)NCC3CCNCC3)C=C2)O1
|
| 529 |
+
COC1=CC=C(C2=CC(C)=CC=C2[N+1](=O)[O-1])C=C1
|
| 530 |
+
CC(OC(C)(C)C)C(=O)NC1CCN(CC2=CC=CC=C2)CC1
|
| 531 |
+
O=C(O)C1=CC=C(N/C(=N\O)C2=CC=CC=C2)C=CC=C1[NH1]
|
| 532 |
+
CO[C@@H1]1COCC[C@@H1]1NC(=O)C2=CC=C3N=C(C4=CC=CC5=CC=CC=C45)[NH1]C3=C2
|
| 533 |
+
COC=C1C=C(N2N=CC3=C(OCCN4CCCCCC4)N=CN=C32)C=C1OC
|
| 534 |
+
NS(=O)(=O)C=CC=C(NC(=O)C=CC=C(NC1=NC2=C(S1)C3=CC=C(Cl)C=C3CC2C)NC)C
|
| 535 |
+
NS(=O)(=O)C1=CC(C2=NN=C(S)S2)=CC=C1N3CCC(OC4=CC=C(C#N)C(Cl)=C4)CC3
|
| 536 |
+
COC1=CC=C(S(=O)(=O)N2CC[C@H1]2C(=O)NC3=CC=C(Cl)C(Cl)=C3)C=C1
|
| 537 |
+
CCCCCCC=C1C=C(N(C)C(=O)C(=O)C=C(C)[NH1]C(C)=C)CC(C)=C1
|
| 538 |
+
CC(C)CC1=NC(O)=C2C(C)=C[NH1]C2=N1
|
| 539 |
+
CN(C(=O)NCC(=O)NCC(=O)N(C)[C@H1](CC1=CC=CC=C12)C=O)C(Cl)C(Cl)=C2
|
| 540 |
+
CCCCCCCCC(=O)NCC1=CC=C(C(C)C)C=C1
|
| 541 |
+
CO[C@@H1]1COCC[C@@H1]1NC(=O)CC2=CC=CC=C2F
|
| 542 |
+
CC1=CC=C(S(=O)(=O)N(CCCN2CCOCC2)CC3=CC=CO3)C=C1
|
| 543 |
+
C1C=CC=CNC(=O)[C@@H1]2CCCCN2C(=O)[C@H1](NC(=O)OC(C)(C)C)C(C)(C)CC=C1
|
| 544 |
+
CCCCCCCCCCC(=O)N[C@@H1](CC1=CC=C(C(=O)OC)C=C1)[C@H1](O)CC(=O)NCC2=CC=CC(OC(C)C)=C2
|
| 545 |
+
CC(O)=NC1=C(N=CC(=C1C)C2=CC=C(OS(=O)(=O)[O-1])C=C2[N+1]=O)[O-1]
|
| 546 |
+
O=C1C=C(OC)C(=O)C=C1OC(C(=O)CCC=C)(C(=O)O)C
|
| 547 |
+
C1C=CC=C(S(=O)(=O)NCCN(C2=CC(C(=O)NC3CC3)=NC=N2)CC)C1
|
| 548 |
+
CCOC(=O)CN1C(=O)N(C2=CC=C(Cl)C=C2)C(=O)C1CC(=O)NC3=CC=C(C(=O)OCC)C=C3
|
| 549 |
+
O=C1C=C(C2=CC=C(Cl)C=C2)N(S(=O)(=O)C3=CC=CC=C3)C1=O
|
| 550 |
+
CC(C)C1=CC2=C(C=C1O)CC[C@@H1]3[C@@H1]2CC[C@]4(C)[C@@H1](C5=CC(=O)OC5)CC[C@]34O
|
| 551 |
+
C1OC=CC=CC2=CC=NC(C)=C2N1CCNC3=NC=CC4=C3C(=O)N(C)C4C
|
| 552 |
+
COC=C1C=C(C2=NN(C3=CC=C(Cl)C=C3)C=C2/C=C\C(=O)NC4=CC=C(Cl)CC(F)(F)F)C4C=C1
|
| 553 |
+
COC=CC(OC)=CCC(=O)NCC1=C(C=C(NCC2=CC=C(C(=O)O)C=C2)C=C1CO)C
|
| 554 |
+
COC1=CC=C2C(=C1)CC3[C@@H1][C@@H1]2CC[C@]4(C)[C@@H1](NC(=O)C=C(C)C)CC[C@]34O
|
| 555 |
+
CC(C)(C)OC(=O)[C@H1](CC1=CC=CC=C1)NC(=O)C(=O)C2=C[NH1]C3=CC=CC=C23
|
| 556 |
+
CC1=CC=C(S(=O)(=O)N2CCSC2C3=CC=C(Cl)C=C3)C=C1
|
| 557 |
+
COC1=CC(C(=O)NCC2=CC=C(Cl)C=C2Cl)=CC=C1N3C=C(C4=CC=C(Cl)C(C=5N=N[NH1]N=5)=C4)C=N3
|
| 558 |
+
COC=CC=C(N1N=CC(Cl)=C1NC(=O)C2=CC=C(Cl)C=C2C)C
|
| 559 |
+
CC1=CC=C(C2=CN3C=C(NC(C)=O)C=CC3=N2)C=C1
|
| 560 |
+
CCOC(=O)C1CCN(S(=O)(=O)C2=CC=CC=C2Br)CC1
|
| 561 |
+
COC1=CC=C([C@H1]2CC(=O)N(C3=CC(Cl)=CC(Cl)=C3)C2=O)C(Cl)=C1
|
| 562 |
+
OC1=NC=NC2=C1N=C(/C=C/C3=CC=C(F)C=C3)N2C(F)(F)F
|
| 563 |
+
CC1=CC=CC(/N=N/C2=CC=CC(O)=C2)=C1
|
| 564 |
+
CCN(CC)CCN(C1=CC=C(NC(=O)C2=CC=C3C(=C2)OCO3)C=C1)C4=CC=CC=C4F
|
| 565 |
+
COC1=CC=C(/C=C/C(=O)OCCNC(C)C)C=C1OC
|
| 566 |
+
O=CC1=CC=CC(C2=CC=CC3=CC=CC=C23)=C1
|
| 567 |
+
CC(=O)N(C=C(C(=O)O)NC(=O)[C@H1](CCCCN)NC(=O)[C@@H1](CC1=CC=CC=C1)NC=O)CC=CC=C
|
| 568 |
+
COC(=O)C1=CC=C(NC(=O)NC2=CC=C(S(=O)(=O)N3CCCC3)C=C2)C=C1
|
| 569 |
+
CCCN(CCC1)CCC2=CC(/C=C/C3=CC=CC=C3)=CC=C2C1
|
| 570 |
+
O=C(O)C1=CC=CN=C1
|
| 571 |
+
COC1=CC=C(CN2CCN(CC3=CC=CC=C3Cl)CC2)C=C1
|
| 572 |
+
COC1=CC=C(CN(CC2=CC=CC=C2)C(=O)C3=CC=C(OCCCN4CCOCC4)C(C(F)(F)F)=C3)C=C1
|
| 573 |
+
COC=C1C=CC(NC(=O)C2CCN(C(=O)C3=CC=C(C4=CC5=CC=CC=C5C=C4C)O3)CC2)=C1
|
| 574 |
+
C1OC=CC=CCNC(=O)C=2SC(=S)N(C3=CC=CC=C3)C=2C=C1
|
| 575 |
+
C1C=CC=C(C(C(=O)NC2CCCC2)N3CCN(CC4=CC=CC=C4F)CC3C)C1
|
| 576 |
+
C1C=CC=C1C(=O)N(C2=CC(F)=CC=C2)C3=NN=C(C)O3
|
| 577 |
+
C=CCOC1=CC=C2C=CC=C3C2=C1C=C(OCC=C4N(C=CC5=CN(C)C6=CC=CC=C56)N=N4)C=CC7=CC=CC=C7N=C3
|
| 578 |
+
COC1=CC=CC=C1NC(=O)C2NN=C(C3=C(N4CCN(CCO)CC4)C(=O)NC3)OC5=CC=CC=C52
|
| 579 |
+
O=COCCCC1(C)C(CCC2(C)C1CCC3C4C(C(=C)C)CCC4(C)CCC32)CC
|
| 580 |
+
CC1=CC=C(NC(=O)/C(CC2=CC=CC=C2)=N/OC3=CC=CC=C3)C=C1
|
| 581 |
+
OC[C@H1]1O[C@@H1](N2C=NC3=C(N)N=C(F)N=C32)[C@H1](O)[C@@H1]1O
|
| 582 |
+
CCOC=C1C=C(C=NN=C(NC(=O)C2=CC3=C(S2)CCC3)S)C=C1OC
|
| 583 |
+
CCOC=CC=C(CNC(=O)C1=CN=C(NC(C)=O)S1C)C
|
| 584 |
+
CO[C@H1]OC1[C@]23CC[C@](O)(/C1=C)[C@H1]2C(=O)O[C@@H1](C)C[C@H1](OC(=O)/C(C)=C/C)[C@H1]3
|
| 585 |
+
CCN(CC)CC1OC=C2C=CC=3[NH1]C4=C(OC)C=C(OC)C=C4C=3C2=C1
|
| 586 |
+
COC1=CC=C(OC)C(CN(C2=CC=CC=C2)S(=O)(=O)C3=CC=C4C(=C3)CCN4C(C)=O)=C1
|
| 587 |
+
O=C1C=C(NCCC2=CC=CC=C2)CC(C)C13OC=4C(Cl)=C(OC)C=C(OC)C=4C3=O
|
| 588 |
+
O=C1C2=CC=CC=C2OCC1NC(C(=O)N)CCC3=CNC=4C=CC(O)=CC=43
|
| 589 |
+
C1C=CC=CN2N=C(C=3C=N[NH1]C=3)C=C2C(CC4=CC=CC=C4)NC(=O)CCNCCC=C1
|
| 590 |
+
C#C[C@](O)CC[C@H1]1[C@@H1]2CCC3=CC(=O)CCC3=C2[C@@H1](C=CC4=C(N(CC(=O)N(CCO)CC5=CC=CC=C5)C6=CC=C(OC(F)(F)F)C(OCC7CO7)=C6C(=O)NS(=O)=O)C8=CC=CC)C=C8C=C4C[C@@]1C
|
| 591 |
+
C1O[C@@H1]/C=C\C=C(/C)C(=O)NC2=CC(=O)C3(NCCC[C@@H1]C[C@@H1](OC(=O)NCC(=O)NCCC4=CC=CC=C4)[C@@H1](O)C(O)C(C)[C@H1]3C2=O)C(=O)CN5CCCC5C(=O)NCCOCCOCCNC(=S)NCCCCCC(=O)N[C@@H1](C(=O)N[C@@H1](CCC(=O)O)C(=O)O[C@@H1])CCOC1=O
|
| 592 |
+
CCOC(=O)C1=CC(O)=CC(=C1C)C(=O)CC(OCC)[C@H1](C)/C=N\O
|
| 593 |
+
C1=CC(C2=CN=CC(OC)=C2)=CC=C1O
|
| 594 |
+
CC(=N1)NCCCN(C(=O)C(C)C)C2=CC=CC=C2C1
|
| 595 |
+
CC/C=C\C/C=C\CCCCCCCC(=O)N[C@H1]C/C=C\C(=O)NCC(=O)O
|
| 596 |
+
CN(C(=O)[C@H1](CC1=CC=CC=C1)NC(=O)C(=O)NC2=CC=C(C3=CC=CC=C3)C=N2)C4=CC=C(N5CCOCC5)C=C4
|
| 597 |
+
CC1=CC=C(C2=CC(C3=CC=CN=C3)=CC=C2N4CCCC4)C=C1C
|
| 598 |
+
O=P(O)(O)OP(=O)(O)OCC(O)COP(=O)(O)O
|
| 599 |
+
CC(C)C1=NC([C@@H1]2CCOC2)=NC3=C1N=NN3CC#N
|
| 600 |
+
CCCCCCCCCCCC(=O)O[C@@H1](CO[C@@H1]1O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]1O)[C@@H1]2O[C@H1](CO)[C@H1](O)[C@H1](O)[C@H1]2O
|
| 601 |
+
C[S+1]([O-1])C1=NC=CN1C=CC=C(C#N)C(C(=O)N/N=C/C2=CC=CC=C2OC(F)F)F
|
| 602 |
+
CC=1[NH1]C(/C=C2\C(=O)NC3=CC=C(N(C)CC4=CC=C(F)C=C4)C=C32)=C(C)C=1/N=N/C5=CC=CC=C5C(F)(F)F
|
| 603 |
+
C1OC=CC=C1NC(=O)C(C)N2CCOCC2C(=O)NC3=CC(Cl)=C(Cl)C=C3Cl
|
| 604 |
+
N#C/C(=C\C1=CN(CC2=CC=CC=C2)N=N1)C(=O)NN3CC(F)(F)C3
|
| 605 |
+
CCC1CC2(CC3=CC=CC=C3C2)C(=O)N1
|
| 606 |
+
O=C(O)C=C1C(=CC2=C(OCC)C=COC2=C1O)CC=C(C)C
|
| 607 |
+
COC1=CC=CC=C1NC(=O)CNC(=O)COC2=CC=CC=C2
|
| 608 |
+
C=C(CO)C(=O)O[C@@H1]C[C@]1(C2)CC[C@@H1](O[C@@H1](C=3)C(=O)C=CN(CC)C=3)[C@](O)(C)[C@H1]2CC1
|
| 609 |
+
C1C=CC=C1N2N=CC(N)=C(C(=O)NCC3=CC=CC=N3)C2=O
|
| 610 |
+
CCOC(=O)C=1[NH1]C2=CC=CC=C2C=1CN(CC3=CC=CC=C3)CC4=CC=CC=C4
|
| 611 |
+
COC1=CC=C(C2CC(=O)OC3=C2C=C(F)C(F)=C3C(F)F)C=C1O
|
| 612 |
+
COC1=CC=CC=C1C2=CC(Cl)=CC(Cl)=C2CNC(=O)C3=CC=C(CS(C)(=O)=O)C(F)=C3
|
| 613 |
+
CCN(CC)C(=O)NC=1C=C(C2=CC=C(NC(=O)C3=CC=CC=C3)C(OC)=C2)N(C)C=1
|
| 614 |
+
COC=C1C=C(NC(=O)C2=CC=CC=C2OC3=CC=CC=C3)C(OC)=C1OC
|
| 615 |
+
CCCN(CCC)CCC(=O)NC1=C(C)C=C(CN2CCOCC2)C=C1C
|
| 616 |
+
O=CNC1(C(=O)N(C)CC(=O)OC(C)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(N=C(O)C)CCCC)CC(C)CCC)CCCC2=C)C=CC=C2C)(C)C(C)CC)CCC(=O)NCC(=O)N(C)C(C(=O)NC(C(=O)NC(C(=O)NC1=CC)CC)CCC)CN(O)C(=O)CCCC)C
|
| 617 |
+
O=C(OCCOC1(OC2CCOC1C2(C)C)COCC(OCC3=CC=CC=C3)COC(=O)C4=CC=CC=C4)C5=CC=CC=C5
|
| 618 |
+
CN(C/C=C/C1=CC=C(/C=C/C2=CC=CC=C2)C=C1C)C3=CC=C4C(=C3)CCO4
|
| 619 |
+
O=C(O)CCC(=O)N1C=C(C(=O)NCCC(C)C)CC(=O)C(C(=O)NC2=CC(OC)=C(OC)C=C2[NH1])C(C1)CC
|
| 620 |
+
COC1=CC=C(CNC(=O)C2=CC(C(=O)N3CCOCC3)=CC=C2Cl)C=C1OC
|
| 621 |
+
CC(=O)N(CC1=CC=CC=C1)C(=O)C2=CC=CC=C2
|
| 622 |
+
COC1=CC=CC=C1O[C@H1]2CN(C3=NC4=C(C=C3F)C(=O)C(C(=O)O)=CN4CCC)O[C@@H1]2C5=CC=C(F)C=C5F
|
| 623 |
+
COC(=O)C1=CC=CC(NC(=O)CC2=CC=C(C3=CC=CC=C3C=4N=N[NH1]N=4)C=C2)=C1
|
| 624 |
+
O=COC1CCC=C2CC2(COC(=O)C=CC3CC4=CC(=CC(O)=C4C(C)C3)C5=CC=O)CC5CC=C(C)C(C(=O)OC6(C(O)C(O)C1)CCCCC6OC)C
|
| 625 |
+
C[S+1]([O-1])C(O)/C=C1\CCCC1=O
|
| 626 |
+
CC(C)C1=CC=C2C(=C1)C3C[C@H1][C@](C)(C(=O)NCCCC(=O)OCCCCOC(=O)/C=C/C4=CC=C(C(=O)O)C=C4C)CC[C@]3CO2
|
| 627 |
+
O=C1C=C(C=CCOC(=O)C=C(OC)CCS)CC(=CC(O)C1(O)C)C
|
| 628 |
+
O=COCCC(OC1CC(=O)OCC1CS2S3CC(NC4)C5=C(C=CC(O)=C5C3OC=CC24)C6NCCCC6COC7=C[NH1]C)=C7CC8=CC(=CC(=C8)C9(O)C%10COCC9%11)CC(C%12=CC%11N=C(N)NC%12)N%10CCCCC
|
| 629 |
+
CC1CCCN(CC(=O)N(C)CC2=CC=CC(C)=C2C)C1
|
| 630 |
+
O=C(O)/C=C/C/C=C\C1[C@@H1]CC[C@@H1]2CCN(CCCF)C[C@@H1]21
|
| 631 |
+
COC=C1C=C(OCC(=O)NCC2=CC=CN=C2)C(C)=C1
|
| 632 |
+
COC1=CC=C(/C=C2\OC(=O)C(N3CCN(C)CC3)=C2OC)COC1OC
|
| 633 |
+
CC(C)CC(OCC(=O)N1CCN(C2=CC=C([N+1](=O)[O-1])C=C2)CC1)C(N)=O
|
| 634 |
+
CC1(C)CCC(CN2CCNC3=CC=C(C(=O)NS(=O)(=O)C4=CC=C(NCCCN5CCOCC5)C(Cl)=C4)C(OC6=CC=CC=7[NH1]C=CC6=7)=C3CC2=CC8=CC=C(Cl)C=C8)C1
|
| 635 |
+
C1S(=O)(=O)NCC=C1C=CC=C(C2=CC(Cl)=C(Cl)C(Cl)=C2)O
|
| 636 |
+
CC[C@@]1(O)C(=O)OCC2=C1C=C3N(C2=O)CC4=C3N=C5C=CC=CC5=C4/C=N\NC(=O)CCCC/C=C/CCCCCCCC(=O)O
|
| 637 |
+
O=COC=C1C(OC(=O)C2)=CCOC(OCCC3(C)C1(CCC(C)C3C4CCCCC(O)(C)CC(OC(=O)C(O)C(C)CC)C4)CC)(C(=O)C)CC2(C)CC
|
| 638 |
+
CC1=CC=C(C(=O)N/C(=C\C2=CC=CO2)C(=O)NCCC3=CC=CS3)C=C1C
|
| 639 |
+
COC1=CC(NC(=O)C2=CC=CC=N2)=CC=C1NC(=O)CSC3=NC=CC(=N3)C4=C(C)C=CS4
|
| 640 |
+
CC1=CC=CC=C1NS(=O)(=O)C2=CC3=CC(=C2)C(=O)C(C(=O)N/N=C/C4=CC=CN=C4)=C3C#N
|
| 641 |
+
CS(=O)(=O)N1C=CC=CC(C2=NC3=CC=CC=C3C(=O)N2C4=CC=C(CN5C6CCC(C6)C5)C=C4C=N1)=C
|
| 642 |
+
CC=CC(NC(=O)C1NN=C2C(SCC3=CC=C(F)C=C3)=NC=CN21)=CC=N
|
| 643 |
+
CC1=CC=CC=C1C(=O)N2CCC3=NC(C4=CC=CO4)=NC=C3CC2
|
| 644 |
+
CC(C)CCC[C@@H1](C)[C@H1]C1C2[C@H1]3[C@@H1]C[C@H1](O[C@@H1]4O[C@H1](C)[C@@H1](O)[C@H1](O)[C@H1]4O[C@@H1]5O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]5OC)C[C@]3(C)[C@H1]2CC[C@]1C
|
| 645 |
+
N#CN1CC[C@@H1]2[C@H1]1C=CN2C3=NC4=C(C=C3F)C(=O)C(C(=O)O)=CN4C(=O)/C=C/C5=CC=CC=C5
|
| 646 |
+
CC1=CC=CC=C1C(=O)NC2CC[C@H1](NC(=O)N3CCCCCC3)C2
|
| 647 |
+
COC=C1C=CC(N(C)C(=O)[C@H1]2CNCCN2C(=O)[C@@H1](NC(=O)C3=CC(CNC(=O)[C@H1](N)CC4=CC=CC=C4)=CC=C3)Cl)CCC=C1
|
| 648 |
+
C1COC=CC=C1S(=O)(=O)NCCOC2=CC=CC(=C2)[C@H1](CC3=CC=CC=C3)NC(=O)C
|
| 649 |
+
CC(=O)NC1=CC(NCC2=CC=C(NC(=O)C3=CC=C(F)C=C3)C=C2)=NC=N1
|
| 650 |
+
CC(=O)N[C@@H1](CCCNC(=N)N)C(=O)N[C@H1]CC(=O)N1CCCC[C@@H1](C(=O)O)NC(=O)[C@@H1]2CCCN2C(=O)[C@H1](CC3=CN=C[NH1]3)NC(=O)[C@H1](CC4=C[NH1]C5=CC=CC=C45)NC(=O)[C@@H1](CCCNC(=N)N)NC(=O)[C@H1](CC6=CC=CC=C6)NC1=O
|
| 651 |
+
C1C=CC=C1CNC(=O)C(=O)[NH1]C2=CC([N+1](=O)[O-1])=CC=C2
|
| 652 |
+
C1OC=CC=C1CNCCC2=C(SC(NC(=O)C3=CC=CC=C3)=C2C(=O)N4CCC)C4C
|
| 653 |
+
CN(C=CC(NCCC1=C[NH1]C2=CC=CC=C12)=NC(NC3=CC=C(OCCOC)C=C3)=N4)CC=CC=N4
|
| 654 |
+
CC1=CC=C(NC(=O)N/N=C/C2=CC=C(C(=O)NO)C=C2)C=C1C
|
| 655 |
+
CCCCCCCCCCCC1=CN(COCCO)C2=CC=CC=C12
|
| 656 |
+
CCO[C@H1]OC(=O)CC1[C@](C)[C@@H1](OC1=O)[C@H1]OC(=O)[C@@]2(C)CCC3[C@H1](C)CC[C@@H1][C@@]3OO2
|
| 657 |
+
CC1=CC=C(N/N=C2\C(=O)NC3=CC=C(C)C=C3C2=O)C=C1C
|
| 658 |
+
O=C([O-1])COC(O[CH0][CH1]1[CH0](O)[CH0]([CH0](O)[CH0](O)CO2)[CH0]([OH1+1][CH0]1[CH1])C(=O)NC(O)C)OCOCOC(OCOCOC(C3OC4OC(CO)C(O)C(O)C4O)C(OCOC(COC(=O)C=C[CH0]5[CH1][CH1][CH0](O)[CH1][CH1]5)C(O)C(O)C)OC(O)C(O)C3OC6OCC(O7)C(O)C6OCOC(C8O)C(OCOC(COC9OC(CO)C(OC%10OC(CO)C(O)C(O)C%10O)C(O)C9)OC(O)C(O)C)NC(=O)CC8OC(O)C(O)C7)OS(=O)(=O)OCOC(O)C2OC(=O)CO
|
| 659 |
+
CC1=CC=CC=C1NC(=O)C=2C=CSC=2NC(=S)NC3=CC=CC=C3
|
| 660 |
+
COC=CC(NC(=O)C1=CC=C(OCC2=CC=CC=C2)N=C1C)C=CC(=O)O
|
| 661 |
+
CC1=CC=CC2=C1C(O)CCC2=O
|
| 662 |
+
O=C(O)[C@@H1]1[C@@H1](O)[C@@H1](O)CN1CC2=CC=C(F)C=C2
|
| 663 |
+
COC1=CC=CC(N2C=C(C(=O)C3=CC=C(C#C[Si](C)(C)C)C=C3)N=N2)=C1
|
| 664 |
+
CC1=CC=C(C(=O)NC2=CC(C(F)(F)F)=CC(C(=O)NC3=CC=CC=C3)=C2C)CC=C1
|
| 665 |
+
C1OC=CC=C(N2C=C(C3=CC=C4C=C[NH1]C4=C3)C(=O)C2=O)C1
|
| 666 |
+
CC=1ON=C(C2=CC=C(Cl)C=C2)C=1CSC3=NN=C(C4=CC=CO4)N3N
|
| 667 |
+
O=C(O)CCCC(=O)NCCNC(=O)CNC(=O)C(NC(=O)CNC(=O)C(NC(=O)CNC(=O)CNC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC=O)CC1=CC=CC=C1)CC2=CNC=3C)=CC=C)C=32)CCC4=CC=CC=C4CC)CCCC)CC(C)C)CCC5=CC=CC=C5)CC(=O)N
|
| 668 |
+
CCCCCCSC(=N)N1C(C(=O)N(C)C)=C(N)N(CC2=CC=CC=C2)C(=O)[NH1]C1=O
|
| 669 |
+
CCCN(CCC)C1=NC2=CC=CC(N)=C2N=C1N
|
| 670 |
+
O=COCC(=O)C(=CCC(C(=O)C(C=O)C(OC)C)CC)COC(=O)CCC
|
| 671 |
+
COC1=CC=CC=C1C=C(C2=CC3=CC=CC=C3N2S(C)(=O)=O)C(=O)NC(C)C
|
| 672 |
+
O=C(OCC(OC(=O)CCCCCCCC=CCC=CCCCCCCO)P(=O)(O)OC(CO)CCCCCC=CCC=CCC=CCC=CC)C=CCC=CCCCCC
|
| 673 |
+
COC=CC=CC(COC(=O)C1=CC=C(F)C=C1)N2CCCCC2C=C
|
| 674 |
+
O=C(O)CCC(NC(=O)C1=CC(Cl)=CC(Cl)=C1C)(O)N2CC[C@](O)(CNC3=CC=NC(Cl)=C3)C2
|
| 675 |
+
O/N=C(\NCCN1CCOCC1)NC2=CC(C3=CC(Cl)=CC=C3Cl)=N[NH1]2
|
| 676 |
+
O=CC1=C(F)C=CC(O)=C1O
|
| 677 |
+
CN(CCC1=CC=CC=N1)C(=O)C2(C3=CC=C4C=CC=CC4=C3)CCCCC2
|
| 678 |
+
N/C(=C/C1=CC=C2C=CC=CC2=[N+1]1[O-1])C(=O)N[C@@H1](CCCCN)C(=O)N3CCCCC3
|
| 679 |
+
CC1=CC=CC(N2CCN(C(=O)NC3=CC=CC=C3C(=O)N(C)C4CCCCC4)CC2)=C1C
|
| 680 |
+
CCCCCCCC[C@H1](C)/C(O)=C/C(=O)O
|
| 681 |
+
CCONC(=O)C1CC(C2=CC=C(OC)C=C2)=NN1C3=CC=CC(Cl)=C3
|
| 682 |
+
COC1=CC2=CC(=C1)N(C[C@H1]3CCC(=O)N3)S(=O)(=O)C4=CC(C(F)(F)F)=CC=C42
|
| 683 |
+
CCOC(=O)NC(CC1C2=CC=CC=C2)CCN(C(=O)CCC3=CC=C(O)C=C3)CC1
|
| 684 |
+
CCN(CC)CCCC(C)NC1=CC(OC)=C(C(=O)/C=C/C2=CC=C(OC)C(OC)=C2)C(OC)=C1
|
| 685 |
+
COC(=O)C=C1C=C(NC(=O)C=2C=C(C3CCCCN3S(=O)(=O)C4=CC=C(Cl)S4)ON=2)C=C1
|
| 686 |
+
CC(C)C(C)NC(=O)C1=CC=C2C(=C1)C(C(C)C(=O)O)=NN2C(=O)CC3CC(CC(C3)C)C
|
| 687 |
+
CC(C)(C)OC(=O)N[C@@H1](CC1=C[NH1]C2=CC=CC=C12)C(=O)N3C4C(C[C@H1]3C(=O)N[C@H1](CC5=CC=CC=C5)C(=O)OCC)CCC4
|
| 688 |
+
COC=C1C=C(C(C(N)=O)N2CCN(C3CCCC3)CC2)C=C1
|
| 689 |
+
O=C1C2=CC=CC=C2C(=O)N1C3=CC=CC=C3
|
| 690 |
+
CNC1(C(=O)N[C@@H1](CC2=C[NH1]C3=CC=CC=C23)C(=O)N4CCC[C@@H1]4C#N)CCCCC1
|
| 691 |
+
CC=CC(N(CC1=CC=C(C2=CC=CC=C2C=3N=N[NH1]N=3)C=C1)C(=O)C4=CC=C(O)C)=C4CC=CCl
|
| 692 |
+
COC=C1C=C(CNC(=O)CC=C2C=CC(OCCCC3CN(CC4=CC=C(OC)C=C4O)CCC3)=C2)C=C1
|
| 693 |
+
CC(C)C1=CC=CC=C1NCCN(CCCCC2=CC=C(C(=O)NCC3CC3(F)F)C=C2C)C
|
| 694 |
+
CC(=O)NS(=O)(=O)C1=CC=C(CCNC(=O)C2=CC=C(CC3=CC=C(C)C=C3)O2)C1
|
| 695 |
+
C=C(Cl)C(=O)NCCCCCCCCCCCCOC(=O)NC1CCCCC1
|
| 696 |
+
CC(C)C(O[Si](C)(C)C)C[C@H1](NC(=O)OC(C)(C)C)C(=O)O
|
| 697 |
+
CCOP(=O)(OCC)C(C)NC(=O)C1=CC=CC=C1
|
| 698 |
+
CC=C1C=CC(C2=CC(CN3CCC4=CC=CC=C4C3)=C(Cl)C=C2O)C=C1
|
| 699 |
+
C1OC2=CC=CC=C2C=CC=C1C3=CN=C(N)C(C#CC4=CC=CC(F)=C4)=N3
|
| 700 |
+
CC1=CC(C(=O)N(CCN(C)C)CSC2CC2)=NN1C
|
| 701 |
+
CC1=CC=CC=C1C(=O)C2=CC=CC(NC(=O)C(=O)NC3CCCCC3)=C2
|
| 702 |
+
CCN(CC)CCNC1=CC=CC(C)=C1NC(=O)N(C)C2=CN=C(NC3=CC=C(N(CCF)CCCl)C=C3)N=C2
|
| 703 |
+
COC1=CC=CC=C1/C=C2\SC(=O)N(CC3=CC=NC=C3)C2=O
|
| 704 |
+
CN(CCNC(=O)C=C1C=CN=CN=C(NC2=CC=C(C3CC3)C(F)=C2)C=C1N4CCO)CC4C(=O)C5CC5
|
| 705 |
+
O=CNC1(C(=O)NC2=CC=CC=C12)C(=O)NCC3CCOC(C)(C)C3
|
| 706 |
+
O=C(O)CC1CCC2(C3C1)CNC2(O)C3CO
|
| 707 |
+
CCC12CCCC3(CCCC(C)(O)C3(C)CO)C1CCC2O
|
| 708 |
+
COC1=CC=C(C(=O)N2CCSC2C3=CC=C(F)C=C3F)C(Cl)=C1
|
| 709 |
+
O=CC1=CC=C(O)C2(C3=CC(=CC=C13)CC(=N)C(=O)C4=C(O)C=CC=C42)CC
|
| 710 |
+
C1C=CC=C(S(=O)(=O)C2=C(C(=O)NC3=CC=CN=C3)OC4=CC=CC=C24)C1
|
| 711 |
+
COC1=CC=CC(/C=C/C(=O)N2CCCCC2)=C1
|
| 712 |
+
O=C(NCCC(N1CCNC(=O)C2=CC=C3N=CC(NC4CC(C5=CC=C(F)C=C5)C4)=NC3)=C2)CC1OC
|
| 713 |
+
COC(=O)C1=CC(CN2CC[C@H1](N3CCN(C)CC3)C2)=C(F)C=C1F
|
| 714 |
+
CCOC(=O)/C(=C/C1=CC=CC=C1I)NC(=O)C2=CC=C(OC)C=C2
|
| 715 |
+
CC=CC1=CC(C=CC2=CC(C3=CC=C4C=CC(N)=C(O)C4=C3NCCC(N)C(C)CCC)=C2)=C1
|
| 716 |
+
O=C(O)C1C2C3CCC1CC3CCC4C5(CCC6C(C)(C)C(O)OCC46C5C)CCC2
|
| 717 |
+
O=CC1=C(OC)C=2OCOC=2C=C1CCN(C(=O)COC3=CC=CC=C3)C
|
| 718 |
+
CC=1[NH1]C2=CC=C(NC(=O)[C@@H1]3CCCN3)C=C2C=1C4[C@H1]OC[C@H1](NC(=O)C5=CC=CC(C(=O)O)=C5)[C@@H1](O)[C@H1]4O
|
| 719 |
+
COC1=CC=CC=C1CNC(=O)[C@H1]2CCCN2C(=O)C3=CC(C4=CC=CC=C4)=NO3
|
| 720 |
+
CC(CC1=CC=C(Cl)C=C1)N2C=NC3=CC=C(F)C=C3C2=O
|
| 721 |
+
COC1=CC(C(=O)NCC2=CC=C3C(=C2)C(=O)N(C)C(=O)N3C)=CC(OC)=C1OC
|
| 722 |
+
CC(C)C1=CC=CC=C1OCC(=O)NC2=CC=CC(Cl)=C2O
|
| 723 |
+
COC1=CC=CC(NC(=O)NC2=C(Cl)C=CC=C2Cl)=C1
|
| 724 |
+
CN(C)S(=O)(=O)NC1=CC=C(S(=O)(=O)NC=2C=C(C)ON=2)C=C1
|
| 725 |
+
CC[C@@](N)(CCCCN)C(=O)O
|
| 726 |
+
N#C/C(=C\C1=CC=C(OCC2=CC=C(Cl)S2)C=C1)C(=O)NC3=CC=CC=N3
|
| 727 |
+
COC=CC=C(C(=O)NC(=S)NC1=NC=C(Br)S1C)C
|
| 728 |
+
CCO[C@]1(C(F)(F)F)CCN(C(=O)C=C2SC(CN3CCN(CCCCOC4=NC=NC(N)=C4C#CC5=CC=C(C(F)(F)F)C=C5)CC3)=N2)CC1
|
| 729 |
+
COC1=CC(NC2CCN(CCO)CC2)=CC=C1NC3=NC4=CC(C)=C(C)C=C4S3
|
| 730 |
+
CCOC(=O)CC(N1CCOCC1)=C2C(=O)NC(=O)NC2=O
|
| 731 |
+
COC=C1C=C(/C=C\S2C(=S)N(CC(=O)N(C)C3=CC=CC=C3)C2)OC=C1
|
| 732 |
+
CCCCCCOC=C1C=C(S(=O)(=O)N2CCCC2CNC(=O)C(=O)NCC)OC=C1
|
| 733 |
+
OC1=NC=NC2=C1C=NN2CCCCC3CCCCC3
|
| 734 |
+
C=CC(C)(SC(=S)NCC1=CC=CN=C1)C(C)C
|
| 735 |
+
O=C(OC1CC2=C(O)C=3C(=O)C=C(OC=3C4=C2OC1(C)C5CC6=CNC(C=C6CCC5C7C8=C(N)NCC=C8C4CC9=CC(O)=CC=C9CC7CON)CCCOC=CC%10)C)COCCC=%11C=CC=CC=%11C(CC#CC)C%10
|
| 736 |
+
C1OC2=CC=CC1(C3=NC4=C([NH1]3)C(C)=NN4C=CC=C(Br)C=C)C2
|
| 737 |
+
COC1=CC=C2C(=C1)CC[C@@H1]2NC=C3C=C(C(=O)N/N=C/C4=CC=CC(Cl)=C4)C=N3
|
| 738 |
+
CC1=CC=C(OCCC2=CC=C(S(C)(=O)=O)S2)C=C1
|
| 739 |
+
COC=CC1=C(CNC(=O)NC2=NC(C3=CC=C(OC(F)(F)F)C=C3)=C4C=CC=CC4)N2C=C1F
|
| 740 |
+
CCCCCCCCCCCCC/C=C/[C@@H1](O)[C@H1](CO[C@@H1]1O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]1O)NC(C)=O
|
| 741 |
+
O=C(OCCOC(OC1C(O)C(OC1CO)OC2C(O)C(O)C(OC2OCC(O)C(OCCO)O[C@H1]CC[C@H1]3C(=CCC4[C@@](C)C3CC[C@]4(C(=O)OCOC(COCOC(C)C(OC5OCC(O)(CO)C5)OC(O)C)OC(OC6OC(CO)C(O)C(O)C6O)C(O)C)OC)C(C)OCCC)CCC(C)CC(O)C(O)C)OC=COC7OC(CO)C(OC8OCC(O)C(O)C8O)C(O)C7O)C=CC(O)=COC
|
| 742 |
+
C1COC(=O)C=CC=CC1NC(=O)NC2=CN=C3C=CC=CC3=C2C
|
| 743 |
+
C1=CCOC=CC2=CC1(C(=O)NC=NC=C(C(C)(C)C)CS)C2
|
| 744 |
+
O=[N+1]([O-1])C1=CC=NC=C1C(=O)N2CCC(C3=C[NH1]C4=CC=C(Cl)C=C34)CC2
|
| 745 |
+
O=C(O)C1=CC=CC(=C1)N=C(SC2CCCC2)NCC3=CC=CC=C3
|
| 746 |
+
COC=CC(CCNC(=O)NCCC1=CC=C(OC)C(OC)=C1C)C=CNC(=O)C2=CC=CC(C3=CC=C(N(C)C)C=C3)=N2
|
| 747 |
+
COC=C1C=C(C(=O)N/N=C/C2=CC=C(S(=O)(=O)NC)C=C2)C=C1OC
|
| 748 |
+
C=CCOC1=CC=C(N(C2=CC=CC=C2)C3=CC=CC=C3)C=C1
|
| 749 |
+
COC=CC=C([C@H1]1CC(=O)N(CC2=CC=CO2)C1C)COC
|
| 750 |
+
CN(CC1=CC=CO1)C(=O)[C@H1]2CC[C@H1](C3CCCCC3)CC2
|
| 751 |
+
COC1=CC=CC=C1C(=O)N[C@@H1]CC[C@@]2(C)[C@@H1]CC[C@@H1]3[C@@H1]2CC[C@]4(C)[C@@H1]([C@H1](C)CCC(N)=O)CC[C@@H1]34
|
| 752 |
+
CN(C(=O)[C@H1]1CNCC2=C1C=NN2C3=CC=C(F)C(F)=C3)C4=CC=CC=C4
|
| 753 |
+
C1OC=C2C=CC1(CNC(=O)C=CC=CN=C(SCC(=O)N3CCC4=CC=CC=C4C3)SC=C)C2
|
| 754 |
+
COC1=CC=C(/C=C/C(=O)CC(=O)/C=C/C2=CC=C(O)C=C2)C(OC)=C1
|
| 755 |
+
COC(=O)C=CC=C(N1C(=O)C(NC2CCC(C3=CC=CC=C3)(C4=CC=CC=C4)CC2C1)=O)P
|
| 756 |
+
CC=1[NH1]N=CC=1C(C2=CC=CC=C2)C3=CC=C(OCCCCCC(=O)O)C=C3
|
| 757 |
+
CC1=CC=C(NC(=O)C2CCCCN2S(=O)(=O)C3=CC=CN=C3Cl)C=C1C
|
| 758 |
+
CC1=CC=C(NC(=O)C2=CC=C(NC(N)=O)C=C2)C=C1
|
| 759 |
+
O=C(O)C1=CC=C(C=C1)COC=CC=CC2OC=C(C(=O)OCCO)C(OC(=O)C)C2OC(=O)CC=C
|
| 760 |
+
CC(=O)NC1=CC=C(S(=O)(=O)N2CCCCC2)C=C1
|
| 761 |
+
COC1=CC=C(C2=CN=C(C(=O)C3CCCN(C(=O)C4=CC=C(F)C=C4F)C3)O2)C=C1
|
| 762 |
+
C1CCN(C(=O)NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(CC)(CO)C(=S)N1Cl
|
| 763 |
+
COC1=CC(C(C2=CC=CC=C2)N3C=CC(=O)C(O)=C3CO)=CC=C1O
|
| 764 |
+
C1=CC(CN2CCCCC2)=CC=C1CCCC3=NC4=CC=CC=C4N3
|
| 765 |
+
CCOP(=O)(OCC)C(NC(=O)C1=CC=C(Cl)C(S(=O)(=O)NCC2=CC=CO2)=C1C)(C)C
|
| 766 |
+
COC1=CC(C2=CSC(C3=CC=C(F)C=C3)=N2)=CC(OC)=C1OC
|
| 767 |
+
CCOC(=O)CN1N=CC2=CC([N+1](=O)[O-1])=CC=C2N1C3=CC=CC=C3
|
| 768 |
+
COC1=CC=C(C(F)(F)F)C=C1NC(=O)CN(C)S(=O)(=O)C2=CN=CC(F)=C2
|
| 769 |
+
CCN(CC)CCCNC(=O)C1=NN(C2=CC=C(OC3=CC=CC=C3)C=C2)C=C1[C@H1]4CC[C@H1](C)CC4
|
| 770 |
+
COC1=CC=C(CN2CCOC[C@@H1]2C3=NN=C(S)N3CC4CCCCC4)C=C1OC
|
| 771 |
+
CC(C)(C)OC(=O)N[C@H1](/C=C/C(=O)N[C@H1](C=O)CC(C)C)N(CC1=CC=CC=C1)[C@H1](O)[C@H1]2CCCN2C(=O)OCC3=CC=CC=C3
|
| 772 |
+
CC1O/C(O)=C\C(COC2C=CC1(C[C@@H1](N3CC[C@H1](O)C3)CC)C2)=NC(C)=C(C(=O)OC)CC4=CC=CC(Cl)=C4Cl
|
| 773 |
+
COC1=CC=CC(C(=O)CSC2=NN=C(C3CC3)O2)=C1
|
| 774 |
+
NS(=O)(=O)C1=CC=C(OCC2=NC(C3=C(F)C=CC=C3F)=N[NH1]2)C=C1
|
| 775 |
+
CC(C(=O)O)C=C1C=CC(C(=O)NC2CC(F)(F)CN2CC3=CC(Cl)=CC(C(F)(F)F)=C3)C=C1
|
| 776 |
+
O=C([O-1])C=C(O1)CS[N+1](CC)CCC1C
|
| 777 |
+
CC(C)(C)OC(=O)NCCCC(=O)NNC(=O)NC1=CC=C(N2CCOCC2)C=C1
|
| 778 |
+
CCN(CC)C1=CC=C(C(=O)O)C2=C1C(=O)C=CC2=O
|
| 779 |
+
CCOC(=O)C(C)(C)NP(=O)(OC[C@H1]1O[C@@H1](N2C=C(/C=N/O)C(=O)[NH1]C2=O)C[C@@H1]1OOC3)CC=CC4=CC=CC=C34
|
| 780 |
+
C1CCCCCC(=O)OCC[C@@H1][C@@H1]1COC[C@H1]2O[C@@H1](N3C=NC=4C(=O)[NH1]C(N)=NC=43)[C@H1](O)[C@@H1]2O[C@@H1]C
|
| 781 |
+
C1O[C@H1](C2)NC=CC=CC(CC3=CC=C(C(F)(F)F)C=C3)=NC1(N4CC5C(CC4)C[S+1]([O-1])C(N)=N5)C2=O
|
| 782 |
+
COC1=CC=C(NN=C(CCNC(=O)COC2=CC=C(F)C=C2)C3=CC=CC=C3C=O)C=C1
|
| 783 |
+
C1OC=CC=C(N2C=NC3=CN=C(N4CCC(F)(F)CC4)N(C)C3=N2)N1
|
| 784 |
+
CC=CC(NC(=O)[C@@H1]1CCCN1C(=O)NCC2=CC=CC=C2)=CN(C)C=O
|
| 785 |
+
O=C1C2=C(O)C=C(OC)C=C2OCC1CC3=CC=C(OC)C(O)=C3
|
| 786 |
+
C1C=CC=C(OCC2=NN=C3SC(C4=CC=C(/C=N/O)C=C4)=NN23)C=C1C
|
| 787 |
+
O=CC1=CC=CC=C1C(=O)C2=C(NCC3=CN=CO3)C=CC(=C2)C(=O)NCC4=CC=CC=C4
|
| 788 |
+
C1C=CC=C1C2=CSC3=C(C=C([N+1](=O)[O-1])C=C23)CCNCC4=CC=CC(C)=C4CC=C
|
| 789 |
+
CCCCCCCCCCCCCCCC(=O)O[C@H1]/C(=C\CCCCCCCCC1=CC=CC=C1)C(=O)NC[C@@H1]O
|
| 790 |
+
CCCCCCCCCCCCCCCC(=O)N[C@@H1](CC1=CC=C(O)C=C1)C(=O)N[C@H1](CC2=C[NH1]C3=CC=CC=C23)C(=O)N[C@@H1](CC(=O)O)C(=O)N[C@@H1]C(=O)NCC(=O)N[C@@H1](CCCN)C(=O)N[C@@H1]([C@@H1](C)O)C(=O)N[C@@H1]([C@@H1](C)O)C(=O)NCC(=O)N[C@@H1](CCCNC(=N)N)C(=O)N[C@H1](C(=O)O)[C@H1](C)O[C@H1](C)C(=O)N[C@@H1]([C@@H1](O)C4=CC=C(Br)C=C4)C(=O)N5CCC[C@@H1]5C(=O)N(C)CC(=O)N[C@H1](C(=O)O)[C@@H1](C)O
|
| 791 |
+
COC=CC1=C(C=C2C=NC(O)=C(C(C)=O)C(=O)N2C3=CC(C)=NC(C)=N3)C=C1F
|
| 792 |
+
COC(=O)C1=CC=CC(N2N=C(C3=CC=C(Cl)C=C3Cl)C(C4=CC=C(C5=CC=NC=C5)C=C4)=N2)=N1
|
| 793 |
+
COC1=CC(OC)=CCN(CCCN2CCCC2)C3=CC=C4N=CC(C=5C=NN(C)C=5)=NC4=C3C1
|
| 794 |
+
O=P(O)(O)OCCC1NC2=C(C=C(C3=CN=C4[NH1]C=CC4=C3)C=C2CC5=CC=CC=C5C)N1
|
| 795 |
+
COC=CC=CC(CN1C(=O)C(=O)N(CC2CCCO2)C1)=O
|
| 796 |
+
CO[C@@H1]1CN(C2=NC(N(C)C)=NC=C2C=C(Cl)C=N)C[C@@H1]1N
|
| 797 |
+
C1C=CC=C(NC(=O)NCCN(C(=O)NC2=CN(C(N)=O)C3=CC(Cl)=CC=C23)CC)CC=C1
|
| 798 |
+
CCCCCN1C(C2=NON=C2N)=NC3=CC(C(F)(F)F)=CC=C31
|
| 799 |
+
CC1=CC=C2C(N3CCN(CCO)CC3)=NC(NCC4=CC=C(SC5CCCCC5)C=C4)=NC2=C1
|
| 800 |
+
CC1/C(=N\NC2=NC3=CC=CC=C3S2)CC(C4=CC=CC=C4)NC1=O
|
| 801 |
+
CCCN(CCC)CCNC(=O)C1=CC(C2=CC=CN=C2)=NC3=CC=CC=C13
|
| 802 |
+
N#C/C(=C\C1=CC=C(F)C=C1)C2=CC(F)=CC=C2OCC3=CC=C(F)C=C3
|
| 803 |
+
O=C(O)CCC(NC(=O)NC1=NC2=CC=CC=C2[NH1]1)C=O
|
| 804 |
+
CC1=CC(C(=O)C2=C(C(=O)O)C=CC=C2C#N)=CC(C)=C1O
|
| 805 |
+
CC(=O)NC1=CC=C(NC(=O)C2=C(C3=CC=CS3)CCC2)C=C1
|
| 806 |
+
CCOC(=O)NCCN(C(=O)CNC(=O)NC1=CC=C2N=NN(C(=O)C2=C1)CCCCCC)C
|
| 807 |
+
O=C(OC1CCC2C=C(CCC2C1(C)C)C3(C)CC4CCCC(OC(=O)C)(C)C34C)CC
|
| 808 |
+
COC1=CC(C(=O)N[C@@H1](C)C2=NN=C[NH1]2)=CC=C1N(CC3=CC=C(C)C=C3)C(C)=O
|
| 809 |
+
C1OC=CC=C(CN2CC=CN(C(C3=CC=C(F)C=C3)C4=CC5=CC=CC=C5N=C4Cl)N2C)C1
|
| 810 |
+
O=C(O)CC1CCN(C(=O)C=2OC=CC=2)CC1CCN3CCN(C4=NC=CC=C4)CC3
|
| 811 |
+
COC=CC1=CC=C(C2=CC(O)=C(OC)C(C(=O)O)=C2)C=CC1=C
|
| 812 |
+
COC1=CC=C(C=2N=C3SC=CN3C=2NC4=NN=C(C5=CC=C(OC)C(F)=C5)S4)C=C1
|
| 813 |
+
O=C([O-1])CC(OC=CC1(CCC(=O)CCCC=2C=CC(O)=CC=2[OH1+1]CCC=C(O)C(O)=C)CC(O)=C1)C=CC3=CC=C(O)C=C3
|
| 814 |
+
COC1=CC=CC=C1CNC(=O)CC(=O)N(CC2=CC=CC=C2)CC3=CC=C(Cl)C=C3
|
| 815 |
+
C(=C(C)C)CCC
|
| 816 |
+
COC1=CC=CC=C1CNC(=O)C(=O)N2CCC(C3=NC(C4=CC=C(OC5=CC=CC=C5)C=C4)=NO3)CC2
|
| 817 |
+
NS(=O)(=O)C1=CC=C(NC(=O)N/N=C/C2=CC=C([N+1](=O)[O-1])C=C2Cl)C=C1
|
| 818 |
+
O=[N+1]([O-1])C1=CC=CC=C1N(CCCCCCCCCCCCN2C3=CC(=NC4=CC=CC=C34)/C=N/C5=CC=C(Cl)C=C5)CC2CC6=CC=CC=C6
|
| 819 |
+
CC1=CC=CC=C1CN2C(=O)C3=CC=CC=C3C2(O)C4=C[NH1]C5=CC=CC=C45
|
| 820 |
+
CCCCCCN(CCC(=O)O)C1=CC=C(NC2=NN=C(C(=O)NC3=C(C)C=CC=C3Cl)S2)C=C1
|
| 821 |
+
O=C1C2=CC=C(OCC=C(C)C3CC(C)C4(OC(=O)CC4C)C(C)C3CCC2)C=C1
|
| 822 |
+
COC=C1C=CC(N(C)CCC(=O)NCCC2=CC=C(S(C)(=O)=O)C=C2)=C1
|
| 823 |
+
CCOC(=O)C(=C\C1=CC=C(Br)C=C1)/C(=N/NC(=O)C2=CC=CC=C2[N+1](=O)[O-1])N(C)C
|
| 824 |
+
O=C1C2=CC=CC=C2NC=C1C(=O)C=3C(O)=C(C(=O)OC=3C)CC=CC(N)=CC=C
|
| 825 |
+
CC1=CC=C(OCC(=O)NC2=CC=C(NC3=NC4=CC=CC=C4N=C3OC)C=C2)C=C1C
|
| 826 |
+
CCN(CC)CCN1C2=CC=CC3=CC=CC(=C23)C14CCN(CC5CC5)CC4
|
| 827 |
+
COC=CC=C(CC(=O)N(C)CC1=NN=CN1CC)COC
|
| 828 |
+
O=P(O)(O)OCCCC
|
| 829 |
+
CC(C1=CC=CC=C1)N(C(=O)C(=O)NC2=NC3=C(C(F)(F)F)C=CC=C3S2C4)CC=CC=C4C(F)(F)F
|
| 830 |
+
CCCCCCCC(=O)O[C@H1]CC[C@@](C1)C=CC[C@H1]2C[C@H1]1CC3[C@](C)[C@@H1]([C@@H1](C)C4CC4C)C[C@@H1]23
|
| 831 |
+
CC(C)C1=CC=C(/C=C/C(=O)NC2=CC=C(C(C)C)C=C2)C=C1
|
| 832 |
+
COC1=CC=C(NC(=O)COC(=O)/C=C/C2=CC=C(O)C(O)=C2)C=C1
|
| 833 |
+
CCON1C(C2=CC=C([N+1](=O)[O-1])C=C2)=CC(C3=CC=CC=C3)=CC1=O
|
| 834 |
+
CC#C[C@]1(O)CC[C@H1]2[C@@H1]3CCC4=CC(O)=CC=C4[C@H1]3CC[C@@]21O
|
| 835 |
+
CC(=O)N[C@H1][C@H1]1O[C@H1]CC2[C@](C)[C@H1]C(=O)C3=C[C@@H1]C[C@@](C)(CNCC[C@@](C)[C@]3(F)[C@@H1](O)C[C@]C)[C@]2(C)CC[C@@H1]1CC
|
| 836 |
+
CC(C)C=1C=C(C(=O)N/N=C\C2=CC=CC=C2)N(C3=CC=CC=C3)N=1
|
| 837 |
+
CC1=CC=CC=C1NS(=O)(=O)C2=CC(C(=O)NC3=CC=CC(Cl)=C3)=CC=C2N(C)CC(F)(F)F
|
| 838 |
+
C1C=CC=C(C(=O)NCC2=CC(Cl)=CC=C2OC)C1
|
| 839 |
+
COC=CC=CC(C=C(/C=C/C1=CC=C([N+1](=O)[O-1])C=C1)SC(S(=O)(=O)C2=CC=CC=C2)=CC)=NC
|
| 840 |
+
O=C(O1)C2=CC(OC)=C(OC)C=C2C3=C(OC)C(O)=CC=C3CC1
|
| 841 |
+
CC1=CC=CC=C1CNC(=O)[C@@H1]2CCCN2C(=O)C3=CC=C(O)C(S(=O)(=O)NC4=CC=CC=C4Cl)=C3
|
| 842 |
+
CCO/N=C\C[C@H1]1[C@](C)(CCO)C[C@H1](CN1)[C@H1]C/C=C\C2=C3C=C(C(OC)=C2)CC[C@]3C
|
| 843 |
+
C1OC=CC=C(N2C=C(CN3CCCC4=CC=CC=C43)N=N2)C1
|
| 844 |
+
COC=C1C(NC(C)CCCNC(=O)[C@@H1](N)CCC2=CC=CC=C2)=C3N=CC=CC3=C1
|
| 845 |
+
O=CC=C(OC)C(=O)CC(=O)C(=C(O)CC)CC
|
| 846 |
+
CCOP(=O)(CC1=CC=CC=C1OC(CF)(F)F)CCC
|
| 847 |
+
O=C1C=C(C2=CC=CC=C2)OC3=CC(OCCN4CCC(N5CCCCC5)CC4)=CC=C13
|
| 848 |
+
CC(=O)NC1=CC=C(NC(=O)N2C=C(C(=O)NCC3=CC=C(C(=O)O)C=C3)C4=CC=CC=C42)C(C(=O)O)=C1
|
| 849 |
+
CC(C)CC1=CN=CC(CC2=CC=C(C(F)(F)F)C=C2)=C1
|
| 850 |
+
COC1=CC=C(C(=O)OCC(=O)NC2=CC=C(C(=O)O)C=C2)C=C1
|
| 851 |
+
CC(C)(C1)C=CC=C(N2N=C(C(C)(C)C)C=C2C3=CN=CN=C3C)N1
|
| 852 |
+
CC=CC1=CC(CNC(=O)C=C2C1(NC(=O)C3CC4CC(CC(C4)C3)C)NC=C2)F
|
| 853 |
+
COC1=CC2=C(C=C1N3C=NC=C(F)C(=O)C(C(=O)O)=CNC=C3C4=CC=C(OC)C=C4)N5C[C@H1](F)C[C@@H1]25
|
| 854 |
+
CC1=CC=CC(C)=C1NC(=O)C=2SC3=NC=C(C=C3C=2C)NC(=O)CCC
|
| 855 |
+
C1C(=O)N[C@@H1](C)C=CC=C1O[C@@H1]CCN(C=NC2=NC(OCC(C)C)=CC=C2)Cl
|
| 856 |
+
COC=CC=C(S(=O)(=O)N(CCC(=O)NCC1=CC=CC=C1F)C2=CC=CC=C2)F
|
| 857 |
+
C=C1N=CN=CC2(C=CN(C[C@H1]3CNC[C@H1]3NN)N2C)[NH1]C=C1
|
| 858 |
+
CN(C(=O)CCC1=CC=CC=C1)C2=CC=C(OCCN3C(=O)CCC3=O)C(OCC4=CC=CC=C4)=C2
|
| 859 |
+
CC1=CC=C(OC(=O)C2=CC=C(C3=CC=CC=C3)N=C2)C(C)=C1
|
| 860 |
+
O=CN1C2(OC)COC(C=CCC3C1)C=C(O)C(OC)=C2C3
|
| 861 |
+
O=C(O)C1=CC=CC(NC=2C=CC(=O)N(C3=CC=CC=C3F)C=2Cl)=C1
|
| 862 |
+
C1C=CC=C1NC(=O)C2=C(NC=O)C=CC=C2OC=C
|
| 863 |
+
CCOC(=O)C1=CC(NC(=O)CC2=CC=C(F)C=C2)=C[NH1]1
|
| 864 |
+
C1C=CC=C(NC=C(C=C(C(=O)O)C(C)C)N=C[NH1]C=O)C1C
|
| 865 |
+
CC(C)(C)C(=O)NCCC(=O)NC=C1C=CC(S(=O)(=O)N(C)C2=CC=CN=C2C)C=C1
|
| 866 |
+
COC1=CC=C(C2=CC=CC(C(F)(F)F)=C2)C=C1OCCNCCNC(=O)C(F)(F)C(F)(F)C(F)(F)F
|
| 867 |
+
CC1=CC(/C=C/C2=CC=C(N=N2)OC=C3C(=O)C(C(=O)O)=CN(C4CC4)C3=C5OC5)=CC=C1OC(=O)C6=CC=CN=C6
|
| 868 |
+
CCCC1CCC(=O)C(C)C(CC)O1
|
| 869 |
+
C=CC[C@H1](O[C@@H1]1O[C@H1](C2O)[C@@H1](O)[C@H1](OC)[C@H1]1O[C@@H1]C)[C@H1](O[C@@H1]3O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]3O)[C@H1](O[C@@H1]4O[C@H1](C)[C@@H1](O)[C@H1](O)[C@H1]4O)[C@@H1](CC5=CC=C(O)C=C5)O2
|
| 870 |
+
CC(C)(C)N(CC1=CC=CN=C1)C(=O)C2=CC=CC(=C2)C3=CC=NC(=N3)NC4=CC=CC(=C4)C
|
| 871 |
+
CC(O)(C=C1C=CC(NC(=O)CN(C#N)CC)=C1)C(F)(F)F
|
| 872 |
+
O=CN1C(=O)C2(CCCCC2)C(=O)N1C3=CC=C(Cl)C(Cl)=C3
|
| 873 |
+
O=CC1=C(O)C=CC=C1C(O)(C2=CC=C(O)C=C2)C
|
| 874 |
+
C1C=CC=C(NC(=O)[C@H1](NC2=CC=C(I)C=C2Cl)C(=O)OC)C1
|
| 875 |
+
CC(=O)NC1=CC=C(F)C(F)=C1
|
| 876 |
+
COC1=CC=C2C=C(C3=CC(OC)=C(OC)C=C3C(=O)C2=O)C=CC=C1
|
| 877 |
+
CCCCCCCC/C=C/CCCCCCCC(=O)OCC(CO[C@H1]1O[C@H1](CO)[C@H1](O)[C@H1](O)[C@@H1]1O)OC(=O)CCCCCCCCCCCCCC(=O)O
|
| 878 |
+
COC=C1C=C(C2=NN(CC(=O)NC3=CC=CC(F)=C3)C(=O)N2CC(=O)NCC4=CC=C(F)C=C4)C=C1
|
| 879 |
+
C1OC=CC2=CC1(C(=O)NC=CC=CC(C(=O)NCCN(CC)CC)C=C)C2
|
| 880 |
+
COC1=CC=CC=C1CNC2[C@@H1](NCCC3=CC=C4C(=C3)OCO4)[C@@H1](O)C2
|
| 881 |
+
COC1=CC2=C(C(OC)=C1OC)C(C(C)=O)=C[C@@H1](C3=CC=C(O)C(OC)=C3)O2
|
| 882 |
+
CCCCCCCCCCCCCC(=O)OCC(CO[C@H1]1O[C@H1](CO)[C@H1](O)[C@H1](O)[C@H1]1O)OC(=O)CCCCC
|
| 883 |
+
O=CC1=C(O)C=CCOC(=O)C2=C(OC)C3=CC(OC)=CC(O)=C3C(=O)C1(O)CC2
|
| 884 |
+
COC=C1C(C(=O)NCC(=O)NCCC2=CC(OC)=CC(OC)=C2)=CC(OC)=C1OC
|
| 885 |
+
NS(=O)(=O)C1=CC=C(NC(=O)NNC2=NC=NC=C2SC3=CC(Cl)=CC=C3)C=C1
|
| 886 |
+
O=[N+1]([O-1])C1=CC=C2[NH1]C(NC3=CC=C(S(=O)(=O)N4CCOCC4)C=C3)=NC2=C1
|
| 887 |
+
CC(C)C1=CC=C(NC2=NSC(N3C=NC4=CC=CC=C43)=N2)C=C1
|
| 888 |
+
CCCCCCCCCCCCCCCCOC1=NC(N)=C(S(=O)(=O)F)C=C1F
|
| 889 |
+
C1COC=C2C=C1C=CC=NC2(N3C=CC(OCC4=CC=CC(F)=C4)=CC3=O)C=C
|
| 890 |
+
C1OC=CC=C(NC(=O)N(NC(=O)CC2CCCC2)C(=O)C3=CC=CC=C3)C1OC
|
| 891 |
+
CC=C1C=CC(CNC2=CC(C(F)(F)F)=NC(NC3=NC4=C(Cl)C=CC=C4N=C3CC)=N2)=N1
|
| 892 |
+
CN1C(N2CCN(C3=CC(C(F)(F)F)=CC=N3)CC2)=NC(C4=CC=NC=C4Cl)=CC1=O
|
| 893 |
+
COC=CC=C(NC1=NC=CC=C1C(=O)NC2=CC=C(C3=CC=C[NH1]3)C=C2C)C
|
| 894 |
+
O=C(O)C=CC1=C(C(=O)NCC=C2C=C(NC(=O)[C@H1]CCC3=C(O)C=CC=C3)C=C2)C=C1
|
| 895 |
+
O=C(O)C=CC1=COC1(C2=CC(O)=C(O)C(=C2C)C(C)CC)O
|
| 896 |
+
O=COCC1C2C(O)(CC=C3CC(OC4OC(C)C(OCOC(C)C(OC5OC(C)C(OC6OCC(O)(CO)C6O)C(OC)C5)OC(OC)C)C(OC)C4)CCC32CC7(O)CCCC(=O)C)C17CC=CC=8C=CC=CC=8
|
| 897 |
+
CC[C@]1(O)CCCN1C(=O)NC(=O)NCC=CC2=CN=C3C=CC(NC4CCN(C)CC4)=CC3=C2
|
| 898 |
+
O=CNC(=O)N(CC1=CC=C2O1)CN=C(C3=CC=C([N+1](=O)[O-1])C=C3)[NH1]C(=O)C2
|
| 899 |
+
O=C1NC(C(=O)N1CC2=CC=C3OCOC3=C2)CCC(=O)NCC4=CC=C(OC)C=C4
|
| 900 |
+
C1COC=CC=C1CNC(=O)C(C2=NS(=O)(=O)C3=CC(C(F)(F)F)=CC=C3N2C)(O)OCCC=C
|
| 901 |
+
O=C1C=C(OC(=C1)C2=CC=CC=3C=CC=CC=32)CNC=4C=CC=CC=4OC
|
| 902 |
+
CC1CCCCC1NC(=O)CNC(=O)NNC(=O)C2=CC=C(OCC3=CC=CC=C3)C=C2
|
| 903 |
+
COC=C1C=C(C(CC(=O)NCC2=CC=C(C(=N)N)C=C2)OC(=O)C3=NOC(C(N)=O)=C3)C(OC)=C1OC
|
| 904 |
+
CCCCC1=NN(CCC)C(=O)N1CC=C2C=C(C3=CC=CC=C3CN4CCC(O)CC4)C=C2
|
| 905 |
+
COC1=CC2=C(NC3CCN(C)CC3)C=CN=C2C=C1OCC
|
| 906 |
+
CCCCCC1=CC(O)=C2C(=C1)OC(C3=CC=C(C)C=C3)CC2=O
|
| 907 |
+
CC1=CC=C(S(=O)(=O)N(CC2=CC=CC=C2Cl)C3CCN(C(C)=O)CC3)C=C1
|
| 908 |
+
C1OC=CC=CC1C(=O)N[C@H1]CC[C@@H1](N2C=NC3=C(C#CC(C)(C)O)N=CN=C32)C=C
|
| 909 |
+
COC1=CC=C(S(=O)(=O)N2CCC(C(=O)NNC(=O)CC3=CC=C(F)C=C3)CC2)C=C1
|
| 910 |
+
CC(C)C1CC(C)(C)C2=CC(OC(=O)NC3=CC=C4C=CC(=O)[NH1]C4=C3)=C(C)C=C21
|
| 911 |
+
C1C(C)C=NOC1CN(C)CCNS(=O)(=O)C2=CC=CC=C2N
|
| 912 |
+
CC1=CC=C(C2=NN=C(N/N=C/C3=CC=CN=C3)O2)C(Cl)=C1
|
| 913 |
+
CC1=CC=C(C(=O)NC2=CC=C(C(=O)NCC3=CC=C(N(C)C)C=C3)C=C2)C(Cl)=C1
|
| 914 |
+
C1OC=CC(/C=N/NC2=NN=CC=N2)C(Br)=C1OCC3=CN([C@@H1]4O[C@H1](CO)[C@@H1](O)[C@H1](O)[C@H1]4O)N=N3
|
| 915 |
+
CC=CC=CC=1N=C2N=CC(NCCC3=CC=NC=C3)=NN2N=1
|
| 916 |
+
CNC[C@@H1]CN1C[C@H1](C=C2C=C(N3C(=O)S/C(=C\C4=CC=C([S+1](C)[O-1])C=C4O)CC3)OC=C2)C1
|
| 917 |
+
CCCN1N=NC(C2=NC=CC=N2)=N1
|
| 918 |
+
O=COC1CC2OC2CC3(OC(=O)C4=CC5=CC6=C(N=CC=C6N=C5C=C4C7=CC=CC8=CC=C(OC)C=C78)C9=CC=C(C(=C9)C)CC=%10[NH1]C%11=CC=CC=C%11C=%10)CC1C3(C)CC
|
| 919 |
+
CC1=CC=C2C(=C1)S(=O)(=O)C3=CC(C4=CC(O)=CC=C4O)=CC=C32
|
| 920 |
+
O=C(O)CCC1=C(N=CN1C=CC2=CC=CC3=C2OCC3)[NH1]C(=CC=4C=CC=CC=4)C
|
| 921 |
+
C1C=CC(N2CCCN(CCC(=O)C3=CC=C(F)C=C3)CC2)=NC1N4CCN(CC5=CC=C(C#N)C=C5)CC4=N
|
| 922 |
+
CCCCCCCCCCCCC1=CC(O)=CC(OC)=C1O
|
| 923 |
+
COC1=CC(NC(=O)C2(NC(C)=O)CCCCC2)=CC(OC)=C1OC
|
| 924 |
+
CCCN(CCC)CCCOC1=CC=C(C2=NN=C(S)O2)C=C1
|
| 925 |
+
CCCCCCCCCC(CCO)N1C=NC(N(C)C)=N1
|
| 926 |
+
CCN(CC)C1=NC=C(OC2=CC=C(C)C=C2C(F)(F)F)C=C1NC3CCCCC3
|
| 927 |
+
CCCCCC1=CC(OC)=C(CC(C=O)=C(N)OCC=C(C)CC)C(OC)=C1
|
| 928 |
+
COC1=CC(CCC(=O)NNC(=O)C2=CC=CC(C(F)(F)F)=C2)=CC=C1OCC3=CC=CC=C3
|
| 929 |
+
C1C=CC=C(C2=CC3=C(C=C2S(=O)(=O)NC4CCN(CC5=CC=C(F)C=C5F)C4=O)CO3)C=C1
|
| 930 |
+
O=CC1=CC=CC=C1N=C(C=CN)CNC(C)C
|
| 931 |
+
CC1=CC=C(S(=O)(=O)C2=CN(OC)C(=O)C=C2OC3=CC(F)=C(Cl)C=C3)C=C1
|
| 932 |
+
NS(=O)(=O)O[C@H1]1CN(CC2CCCCC2)C[C@@H1]1C(=O)NC3=CC=C(N4CCCCC4)C=C3
|
| 933 |
+
CNC[C@H1](NC1=NC=NC=2[NH1]N=CC1=2)[C@@H1](C3=C(F)C(F)=C(F)C(F)=C3)F
|
| 934 |
+
CC(=O)N(CC1NC(C)=C(C(=O)NCC2=CC=C(Cl)C=C2)C3=CC(Cl)=CC=C31)CC4=CC=CO4
|
| 935 |
+
CONC(=O)CC(C1=C[NH1]C2=CC=CC=C12)[NH1]CC
|
| 936 |
+
COC1=CC=C(N2N=C3C(=O)N(CC(=O)NC4=CC=CC(F)=C4)N=C(C)C3=C2C(N)=O)C=C1
|
| 937 |
+
C1OC=CC(/C=C/C(=O)OCC(=O)NC2=C(F)C=C(F)C=C2Cl)=C1O
|
| 938 |
+
CCN(CC)C1=CC=CC(=C12)C(=O)N(C[C@@]3(C#CC4=CC(C5=CC=CC=C5OC(F)(F)F)=CS4N)C(=O)N(C6CC6)C3)C2=O
|
| 939 |
+
C1COC=CC=C1NC(=O)CNC(=O)C(C2=CC(Cl)=CC=C2Cl)=CC=C3N=C(C4CC4)[NH1]C3=C
|
| 940 |
+
COC(=O)C=CC=C(NC(=O)C1=CC=C(OC)C=C1OC)C
|
| 941 |
+
COC=CC=C(C1(C#N)CC(CN2CCCCC2)C1C)COC
|
| 942 |
+
OC1=CC(=CC=C1OC)CCNCC
|
| 943 |
+
COC(=O)C1=CC=CN=C1O[C@@H1]2O[C@H1](CO)[C@H1](O)[C@H1](O)[C@H1]2O
|
| 944 |
+
CCOC(=O)[C@H1](C)NP(=O)(OC[C@H1]1O[C@@H1](N2C=CC(=O)[NH1]C2=O)[C@](C)(F)[C@@H1]1O)OC3=CC=CC4=CC=CC=C34
|
| 945 |
+
CCCCC1CNC=C(CN2CCC(C3C2)NC(=O)C=CC4=CC(Cl)=CC=C4O3)N1
|
| 946 |
+
CCCN(CCC)[C@@H1]1CCC2=C(C3=CC=C(F)C=C3)C(C)=NN2C1
|
| 947 |
+
O=C(O)CCCCNCC=C(O)C=C(O)C=1C(=O)C(O)=C(O)OC=1
|
| 948 |
+
O=C(O)C1=CC=CC=C1N2N=NC=C2C3=CC=C(OC)C(OC)=C3
|
| 949 |
+
CC(C)(C)OC(=O)N1CC2=CC(CN3C(=O)C(=O)C4=CC(Cl)=CC=C43)=CC=C2C1
|
| 950 |
+
CCOC(=O)C=1C=CSC=1NC(=O)C2=CC(C3=CC=NC=C3)=NC4=CC=CC=C24
|
| 951 |
+
CN(C(=O)C1NN=NC1=O)C(C2=CC=CC=C2)C3=CC=CC=C3
|
| 952 |
+
CN(C(=O)COC(=O)CC1=CC=C([N+1](=O)[O-1])C=C1)C2CCS(=O)(=O)C2
|
| 953 |
+
C1C(C)CC[C@](C(=O)O)CCC[C@]2(C)C1=CC[C@@H1]3[C@@]4(C)CC[C@H1](OC(=O)/C=C/C5=CC=C(C6=NN=N[NH1]6)C=C5)C(C)(C)[C@@H1]4CC[C@]32C[C@@H1]
|
| 954 |
+
CC1=CC=CC=C1CNC(=O)C=2C=C(NC(=O)C3=CC(C4=CC=CC=N4)=C(Cl)C=C3Cl)N(C5=CC=CC=C5)N=2
|
| 955 |
+
COC1=CC(CNC(=O)CC(=O)N2CCOCC2)=CC=C1OCC(=O)N(C)CCC3=CC=CC=N3
|
| 956 |
+
O=C1C2=CC=CC=C2CN1C3=CC=CC(Cl)=C3C(=O)N(C4=CC=C(C=C4)C5)COCC5NCC6=CC=CC=C6CC
|
| 957 |
+
CCOC(=O)N1CCN(C(=O)CC(C)NC(=O)C2=CC=CC=C2F)CC1
|
| 958 |
+
CCOC(=O)C=C(N(C)C1=CC=CC2=C1)C(C3=CC=CC=C3)=NN(C4=CC=CC=C4)C2C
|
| 959 |
+
CCOC(=O)C=C(N1C(=O)CNC(=O)CNC(=O)N2N=C(C)C3=CC=CC=C32)SC(C)=C1C
|
| 960 |
+
C1C(C)CCCN1CCC(CC2=CC=CC=C2)C3=CC(OCCN4CCOCC4)=CS3C
|
| 961 |
+
O=C(O)CCCCCNC(=O)CC(OC1=CC=CC=C1C(=O)NC2=CC=C3C(=C2)OCCO3)C4=CC=C(F)C=C4
|
| 962 |
+
C1C(C)C(=O)NC=CC=CC1C=2C=C(C3=CC=CC(NC(=O)C4=CC=CS4)=C3)[NH1]C(=O)C=2C#N
|
| 963 |
+
CC1CN(S(=O)(=O)C2=CC=C(C(=O)NC3=CC=CC=C3)C=C2)CC(C)O1
|
| 964 |
+
CC=1[NH1]C(=O)[NH1]C(=O)C=1NC(=O)COC2=CC=CC=C2
|
| 965 |
+
C1OC=CC=C1C=C2C=CN(C3=CC=C(OC)C=C3)C(=O)C2(C)C4=CC=CC=C4C=C
|
| 966 |
+
O=C(O)CCC(NC(=O)C=1N=C(SC=1)C=2SC=CC=2CCC)C(=C)CC(=O)N3CC4C5=CC=CC(=O)N5CC(C3)C4
|
| 967 |
+
O=COC1=CCOC(C)(C1)C(CC(=O)OC)C=C(O)C2C3=CC=C(O)C=C3CCC2(O)OCOC
|
| 968 |
+
COC1=CC=C(C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4C(=O)NO)C=C1
|
| 969 |
+
C1=CC(COC2=CC=CC=C2)=CC([N+1](=O)[O-1])=C1
|
| 970 |
+
COC(=O)C1=CC(/C=C/C2=CC=C(OC)C(O)=C2)=CC=C1NC(=O)C3=CC=C(C4=CC=C(C)C=C4)O3
|
| 971 |
+
C1C=CC=C1[C@H1]2C3=CC=CC=C3C[C@@H1]2NC(=O)C4=CN=CC=N4
|
| 972 |
+
COC1=CC=C(NN=NC(C2CCN(S(=O)(=O)C3=CC=C(F)C(C)=C3)CC2)=NC=O)C=C1
|
| 973 |
+
CC(=O)N(CC1=CC=C2C(=C1)OCO2)CC3=CC=CO3
|
| 974 |
+
C1=CN=CC(CNC2=NC(N3C=CC4=CC(C#N)=CN=C43)=C(Cl)C=C2Cl)=N1
|
| 975 |
+
O=C(OC1CC(OC(=O)C)C2(C)C(OC(=O)C)C3OC3C2(O)C(OC(=O)C)C(OC(=O)C)(C)CC(OC(=O)C(C)C)C14OC4CCC)C
|
| 976 |
+
COC=CC=C(NC(=O)CN1N=C2C(C3=CC=CO3)=NC=CN2C1=O)[N+1](=O)[O-1]
|
model_eval.ipynb
ADDED
|
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|
|
|