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# PreMode
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This is the repository for our manuscript "PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context" posted on bioRxiv: https://www.biorxiv.org/content/10.1101/2024.02.20.581321v2
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For PTEN, column `logits.1` is predicted stability, 0 is loss, 1 is neutral, `logits.2` is predicted enzyme activity, 0 is loss, 1 is neutral
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## Figures
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Please go to `analysis/` folder and run the corresponding R scripts.
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---
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language:
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- en
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pipeline_tag: graph-ml
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tags:
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- biology
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---
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# PreMode
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This is the repository for our manuscript "PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context" posted on bioRxiv: https://www.biorxiv.org/content/10.1101/2024.02.20.581321v2
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For PTEN, column `logits.1` is predicted stability, 0 is loss, 1 is neutral, `logits.2` is predicted enzyme activity, 0 is loss, 1 is neutral
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## Figures
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Please go to `analysis/` folder and run the corresponding R scripts.
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