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README.md
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# How to Use
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Download Model from Hugging Face
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from huggingface_hub import hf_hub_download
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# Download ACE2 RBD model/General model
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model_path = hf_hub_download(repo_id="hbp5181/ESM2-GBT", filename="ACE2_RBD_ESM2-GBT.json")
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Load Model in CatBoost
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from catboost import CatBoostRegressor
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model = CatBoostRegressor()
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model.load_model(model_path, format="json")
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Training Details
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• Feature Extraction: ESM2 embeddings (33-layer transformer, 650M params)
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• Training Algorithm: CatBoost Gradient Boosting
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• Dataset:
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ACE2 RBD: https://github.com/jbloomlab/SARSr-CoV_homolog_survey
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General: https://zenodo.org/records/14271435
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• Evaluation Metrics: RMSE, R^2
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# Applications
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# How to Use
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Download Model from Hugging Face
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from huggingface_hub import hf_hub_download
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# Download ACE2 RBD model/General model
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model_path = hf_hub_download(repo_id="hbp5181/ESM2-GBT", filename="ACE2_RBD_ESM2-GBT.json")
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Load Model in CatBoost
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from catboost import CatBoostRegressor
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model = CatBoostRegressor()
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model.load_model(model_path, format="json")
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# Training Details
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• Feature Extraction: ESM2 embeddings (33-layer transformer, 650M params)
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• Training Algorithm: CatBoost Gradient Boosting
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• Dataset:
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ACE2 RBD: https://github.com/jbloomlab/SARSr-CoV_homolog_survey
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General: https://zenodo.org/records/14271435
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• Evaluation Metrics: RMSE, R^2
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# Applications
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