File size: 101,017 Bytes
5374a2d |
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 716 717 718 719 720 721 722 723 724 725 726 727 728 729 730 731 732 733 734 735 736 737 738 739 740 741 742 743 744 745 746 747 748 749 750 751 752 753 754 755 756 757 758 759 760 761 762 763 764 765 766 767 768 769 770 771 772 773 774 775 776 777 778 779 780 781 782 783 784 785 786 787 788 789 790 791 792 793 794 795 796 797 798 799 800 801 802 803 804 805 806 807 808 809 810 811 812 813 814 815 816 817 818 819 820 821 822 823 824 825 826 827 828 829 830 831 832 833 834 835 836 837 838 839 840 841 842 843 844 845 846 847 848 849 850 851 852 853 854 855 856 857 858 859 860 861 862 863 864 865 866 867 868 869 870 871 872 873 874 875 876 877 878 879 880 881 882 883 884 885 886 887 888 889 890 891 892 893 894 895 896 897 898 899 900 901 902 |
[
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130176 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CNN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":667
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":464
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000204472 expression is quantified. Does this perturbation result in a significant change in ENSG00000204472 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1962
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000256713 expression is quantified. Does this perturbation result in a significant change in ENSG00000256713 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PGA5 expression is quantified. Does this perturbation result in a significant change in PGA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":702
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":349
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000113369 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000113369 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":78
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1006
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000118515 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in SGK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2555
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2570
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000166340 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1157
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000170608 is measured. Determine whether ENSG00000170608 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of FOXA3 is measured. Determine whether FOXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1066
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000077063 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CTTNBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1617
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000148180 is measured. Does this perturbation cause a significant change in ENSG00000148180 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1340
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000070214. Does perturbing ZBTB1 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of SLC44A1. Does perturbing ZBTB1 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3021
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000085185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of BCORL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":187
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1578
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163499 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163499 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and CRYBA2 expression is observed. Does this perturbation lead to a significant difference in CRYBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":983
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130176 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130176 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CNN1 expression is observed. Does this perturbation lead to a significant difference in CNN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":663
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000279669 is measured. Does this perturbation cause a significant change in ENSG00000279669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of RP11-717F1.1 is measured. Does this perturbation cause a significant change in RP11-717F1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2670
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1409
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000143498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TAF1A expression is observed. Does this perturbation lead to a significant difference in TAF1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2733
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000157557. Does perturbing ETS2 lead to a significant change in ENSG00000157557 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ETS2. Does perturbing ETS2 lead to a significant change in ETS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":951
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000143401 is measured. Determine whether ENSG00000143401 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ANP32E is measured. Determine whether ANP32E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2086
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Does this perturbation cause a significant change in ENSG00000124762 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":360
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000105697. Does perturbing S1PR2 lead to a significant change in ENSG00000105697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HAMP. Does perturbing S1PR2 lead to a significant change in HAMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2481
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102575 is measured. Determine whether ENSG00000102575 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2936
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":863
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1557
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":655
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000148180 expression is observed. Does this perturbation lead to a significant difference in ENSG00000148180 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1343
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000143162 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CREG1 expression. Decide whether this perturbation leads to a significant alteration in CREG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1598
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000183770. Does perturbing C3orf72 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of FOXL2. Does perturbing C3orf72 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":291
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000002586. Does perturbing CBL lead to a significant change in ENSG00000002586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of CD99. Does perturbing CBL lead to a significant change in CD99 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":331
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000154127 expression is observed. Does this perturbation lead to a significant difference in ENSG00000154127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2983
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3076
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000182871 is measured. Determine whether ENSG00000182871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of COL18A1 is measured. Determine whether COL18A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2326
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000125931 is measured. Does this perturbation cause a significant change in ENSG00000125931 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of CITED1 is measured. Does this perturbation cause a significant change in CITED1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":570
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Does this perturbation cause a significant change in ENSG00000079102 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Does this perturbation cause a significant change in RUNX1T1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2430
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000205277. Does this perturbation cause a significant change in ENSG00000205277 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of MUC12. Does this perturbation cause a significant change in MUC12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3134
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163499. Does this perturbation cause a significant change in ENSG00000163499 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of CRYBA2. Does this perturbation cause a significant change in CRYBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":964
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Determine whether ENSG00000108984 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Determine whether MAP2K6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1846
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000103241 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000103241 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1088
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000127831 expression is quantified. Does this perturbation result in a significant change in ENSG00000127831 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and VIL1 expression is quantified. Does this perturbation result in a significant change in VIL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1752
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1956
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130176 expression is quantified. Does this perturbation result in a significant change in ENSG00000130176 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CNN1 expression is quantified. Does this perturbation result in a significant change in CNN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":672
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000077063 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000077063 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CTTNBP2 expression. Decide whether this perturbation leads to a significant alteration in CTTNBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1618
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2514
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000115255 is measured. Does this perturbation cause a significant change in ENSG00000115255 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":620
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is quantified. Does this perturbation result in a significant change in ENSG00000108984 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and MAP2K6 expression is quantified. Does this perturbation result in a significant change in MAP2K6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1842
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000159556 expression is quantified. Does this perturbation result in a significant change in ENSG00000159556 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ISL2 expression is quantified. Does this perturbation result in a significant change in ISL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1502
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000174498. Does this perturbation cause a significant change in ENSG00000174498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1424
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":884
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000127831 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127831 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and VIL1 expression is observed. Does this perturbation lead to a significant difference in VIL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1753
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000188536 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188536 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HBA2 expression. Decide whether this perturbation leads to a significant alteration in HBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2478
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000130656. Does perturbing RREB1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of HBZ. Does perturbing RREB1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2411
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":358
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":104
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000164920 expression is quantified. Does this perturbation result in a significant change in ENSG00000164920 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and OSR2 expression is quantified. Does this perturbation result in a significant change in OSR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2102
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000231312 expression is measured. Determine whether ENSG00000231312 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1869
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000034152 expression is measured. Determine whether ENSG00000034152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and MAP2K3 expression is measured. Determine whether MAP2K3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1809
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000256713 expression is observed. Does this perturbation lead to a significant difference in ENSG00000256713 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PGA5 expression is observed. Does this perturbation lead to a significant difference in PGA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":703
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Does this perturbation cause a significant change in ENSG00000030110 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":130
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163497 is measured. Does this perturbation cause a significant change in ENSG00000163497 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":970
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000197965 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in MPZL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2125
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":852
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":883
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000158373. Does perturbing NIT1 lead to a significant change in ENSG00000158373 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H2BD. Does perturbing NIT1 lead to a significant change in HIST1H2BD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2091
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is quantified. Does this perturbation result in a significant change in ENSG00000116871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1922
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is measured. Determine whether ENSG00000116871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1929
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000143162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CREG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1595
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000105939 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105939 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3093
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":389
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000168140 is measured. Does this perturbation cause a significant change in ENSG00000168140 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of VASN is measured. Does this perturbation cause a significant change in VASN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2020
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000116871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1938
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3059
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1078
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000117139 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117139 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor KDM5B expression. Decide whether this perturbation leads to a significant alteration in KDM5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3148
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000103241 expression is observed. Does this perturbation lead to a significant difference in ENSG00000103241 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1083
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000129514. Does perturbing FOXA1 lead to a significant change in ENSG00000129514 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FOXA1. Does perturbing FOXA1 lead to a significant change in FOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1021
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000099625 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of C19orf26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":247
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000183770. Does perturbing FOXL2 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FOXL2. Does perturbing FOXL2 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1111
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2294
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000162878. Does this perturbation cause a significant change in ENSG00000162878 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":604
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000105939 expression is measured. Determine whether ENSG00000105939 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3099
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000104894 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":777
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000237330 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RNF223 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2405
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000118777 expression is measured. Determine whether ENSG00000118777 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ABCG2 expression is measured. Determine whether ABCG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3009
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000184697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CLDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":635
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":870
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000134321 expression is observed. Does this perturbation lead to a significant difference in ENSG00000134321 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":582
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000114315 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000114315 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor HES1 expression. Decide whether this perturbation leads to a significant alteration in HES1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2038
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000030110. Does this perturbation cause a significant change in ENSG00000030110 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":134
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3115
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000117139 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117139 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3143
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is quantified. Does this perturbation result in a significant change in ENSG00000174498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1412
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000186051 is measured. Determine whether ENSG00000186051 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of TAL2 is measured. Determine whether TAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2336
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000117091 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117091 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CD48 expression. Decide whether this perturbation leads to a significant alteration in CD48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1378
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000120738 expression is observed. Does this perturbation lead to a significant difference in ENSG00000120738 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and EGR1 expression is observed. Does this perturbation lead to a significant difference in EGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2663
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000162878. Does perturbing CKS1B lead to a significant change in ENSG00000162878 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of PKDCC. Does perturbing CKS1B lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":601
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000004939 is measured. Determine whether ENSG00000004939 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of SLC4A1 is measured. Determine whether SLC4A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2636
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":40
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000153012. Does perturbing CEBPB lead to a significant change in ENSG00000153012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of LGI2. Does perturbing CEBPB lead to a significant change in LGI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":491
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000266976 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1857
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000254614. Does perturbing SLC4A1 lead to a significant change in ENSG00000254614 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AP003068.23. Does perturbing SLC4A1 lead to a significant change in AP003068.23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2611
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000114315. Does this perturbation cause a significant change in ENSG00000114315 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of HES1. Does this perturbation cause a significant change in HES1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2034
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000117091 expression is measured. Determine whether ENSG00000117091 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CD48 expression is measured. Determine whether CD48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1379
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2423
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000237330 expression is quantified. Does this perturbation result in a significant change in ENSG00000237330 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RNF223 expression is quantified. Does this perturbation result in a significant change in RNF223 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2402
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000137841 expression is quantified. Does this perturbation result in a significant change in ENSG00000137841 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PLCB2 expression is quantified. Does this perturbation result in a significant change in PLCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2132
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2072
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000182871 expression is quantified. Does this perturbation result in a significant change in ENSG00000182871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and COL18A1 expression is quantified. Does this perturbation result in a significant change in COL18A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2322
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1895
},
{
"question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000071967 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in CYBRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1495
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000153012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of LGI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":487
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000188483 expression is measured. Determine whether ENSG00000188483 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and IER5L expression is measured. Determine whether IER5L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1399
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":799
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000198758. Does perturbing HNF4A lead to a significant change in ENSG00000198758 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of EPS8L3. Does perturbing HNF4A lead to a significant change in EPS8L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1281
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000158517 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158517 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and NCF1 expression is observed. Does this perturbation lead to a significant difference in NCF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":473
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1984
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000079102 expression is observed. Does this perturbation lead to a significant difference in ENSG00000079102 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and RUNX1T1 expression is observed. Does this perturbation lead to a significant difference in RUNX1T1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2433
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1458
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2007
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2847
},
{
"question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000090382 expression is measured. Determine whether ENSG00000090382 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LYZ expression is measured. Determine whether LYZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1059
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3046
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2248
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000133317. Does this perturbation cause a significant change in ENSG00000133317 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2454
},
{
"question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000170689. Does this perturbation cause a significant change in ENSG00000170689 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of HOXB9. Does this perturbation cause a significant change in HOXB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1324
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000256713 is measured. Determine whether ENSG00000256713 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PGA5 is measured. Determine whether PGA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":706
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000174498. Does perturbing IGDCC3 lead to a significant change in ENSG00000174498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of IGDCC3. Does perturbing IGDCC3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1411
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":3077
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000115844 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of DLX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":827
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000101076 is measured. Does this perturbation cause a significant change in ENSG00000101076 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of HNF4A is measured. Does this perturbation cause a significant change in HNF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1260
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":353
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000106546 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106546 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and AHR expression is observed. Does this perturbation lead to a significant difference in AHR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":13
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is quantified. Does this perturbation result in a significant change in ENSG00000079102 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is quantified. Does this perturbation result in a significant change in RUNX1T1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2432
},
{
"question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2410
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163499 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of CRYBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":987
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000163520 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of FBLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1187
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000170180 is measured. Determine whether ENSG00000170180 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPA is measured. Determine whether GYPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":716
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":42
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Determine whether ENSG00000169410 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Determine whether PTPN9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2346
},
{
"question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000272211 expression is observed. Does this perturbation lead to a significant difference in ENSG00000272211 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and RP11-347P5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-347P5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1703
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2516
},
{
"question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000104903 is measured. Determine whether ENSG00000104903 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of LYL1 is measured. Determine whether LYL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1746
},
{
"question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000069482. Does perturbing MAP2K3 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of GAL. Does perturbing MAP2K3 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1821
},
{
"question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000134321 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":7
},
{
"question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000105697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"Yes",
"question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HAMP expression. Decide whether this perturbation leads to a significant alteration in HAMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":2488
},
{
"question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000279529 expression is quantified. Does this perturbation result in a significant change in ENSG00000279529 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"answer":"No",
"question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and CTD-3222D19.8 expression is quantified. Does this perturbation result in a significant change in CTD-3222D19.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
"_id":1642
}
] |