examples/pertqa/norman_train.csv

,question,answer,question_new
667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130176 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CNN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000204472 expression is quantified. Does this perturbation result in a significant change in ENSG00000204472 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000256713 expression is quantified. Does this perturbation result in a significant change in ENSG00000256713 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PGA5 expression is quantified. Does this perturbation result in a significant change in PGA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
78,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000113369 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000113369 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000118515 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in SGK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2570,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000166340 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000170608 is measured. Determine whether ENSG00000170608 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of FOXA3 is measured. Determine whether FOXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000077063 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CTTNBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1340,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000148180 is measured. Does this perturbation cause a significant change in ENSG00000148180 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of GSN is measured. Does this perturbation cause a significant change in GSN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000070214. Does perturbing ZBTB1 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of SLC44A1. Does perturbing ZBTB1 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000085185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of BCORL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1578,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
983,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163499 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163499 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and CRYBA2 expression is observed. Does this perturbation lead to a significant difference in CRYBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
663,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130176 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130176 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CNN1 expression is observed. Does this perturbation lead to a significant difference in CNN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2670,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000279669 is measured. Does this perturbation cause a significant change in ENSG00000279669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of RP11-717F1.1 is measured. Does this perturbation cause a significant change in RP11-717F1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2733,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000143498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TAF1A expression is observed. Does this perturbation lead to a significant difference in TAF1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000157557. Does perturbing ETS2 lead to a significant change in ENSG00000157557 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ETS2. Does perturbing ETS2 lead to a significant change in ETS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000143401 is measured. Determine whether ENSG00000143401 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ANP32E is measured. Determine whether ANP32E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
360,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Does this perturbation cause a significant change in ENSG00000124762 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000105697. Does perturbing S1PR2 lead to a significant change in ENSG00000105697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HAMP. Does perturbing S1PR2 lead to a significant change in HAMP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102575 is measured. Determine whether ENSG00000102575 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
863,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1343,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000148180 expression is observed. Does this perturbation lead to a significant difference in ENSG00000148180 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and GSN expression is observed. Does this perturbation lead to a significant difference in GSN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1598,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000143162 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CREG1 expression. Decide whether this perturbation leads to a significant alteration in CREG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000183770. Does perturbing C3orf72 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of FOXL2. Does perturbing C3orf72 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000002586. Does perturbing CBL lead to a significant change in ENSG00000002586 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of CD99. Does perturbing CBL lead to a significant change in CD99 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2983,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000154127 expression is observed. Does this perturbation lead to a significant difference in ENSG00000154127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
3076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000182871 is measured. Determine whether ENSG00000182871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of COL18A1 is measured. Determine whether COL18A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
570,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000125931 is measured. Does this perturbation cause a significant change in ENSG00000125931 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of CITED1 is measured. Does this perturbation cause a significant change in CITED1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2430,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Does this perturbation cause a significant change in ENSG00000079102 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Does this perturbation cause a significant change in RUNX1T1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000205277. Does this perturbation cause a significant change in ENSG00000205277 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of MUC12. Does this perturbation cause a significant change in MUC12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163499. Does this perturbation cause a significant change in ENSG00000163499 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of CRYBA2. Does this perturbation cause a significant change in CRYBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Determine whether ENSG00000108984 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Determine whether MAP2K6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1088,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000103241 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000103241 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000127831 expression is quantified. Does this perturbation result in a significant change in ENSG00000127831 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and VIL1 expression is quantified. Does this perturbation result in a significant change in VIL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130176 expression is quantified. Does this perturbation result in a significant change in ENSG00000130176 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CNN1 expression is quantified. Does this perturbation result in a significant change in CNN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1618,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000077063 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000077063 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CTTNBP2 expression. Decide whether this perturbation leads to a significant alteration in CTTNBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
620,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000115255 is measured. Does this perturbation cause a significant change in ENSG00000115255 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is quantified. Does this perturbation result in a significant change in ENSG00000108984 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and MAP2K6 expression is quantified. Does this perturbation result in a significant change in MAP2K6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000159556 expression is quantified. Does this perturbation result in a significant change in ENSG00000159556 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ISL2 expression is quantified. Does this perturbation result in a significant change in ISL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000174498. Does this perturbation cause a significant change in ENSG00000174498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1753,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000127831 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127831 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and VIL1 expression is observed. Does this perturbation lead to a significant difference in VIL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2478,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000188536 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188536 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HBA2 expression. Decide whether this perturbation leads to a significant alteration in HBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000130656. Does perturbing RREB1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of HBZ. Does perturbing RREB1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
358,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000164920 expression is quantified. Does this perturbation result in a significant change in ENSG00000164920 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and OSR2 expression is quantified. Does this perturbation result in a significant change in OSR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000231312 expression is measured. Determine whether ENSG00000231312 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000034152 expression is measured. Determine whether ENSG00000034152 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and MAP2K3 expression is measured. Determine whether MAP2K3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
703,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000256713 expression is observed. Does this perturbation lead to a significant difference in ENSG00000256713 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PGA5 expression is observed. Does this perturbation lead to a significant difference in PGA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
130,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Does this perturbation cause a significant change in ENSG00000030110 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
970,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163497 is measured. Does this perturbation cause a significant change in ENSG00000163497 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000197965 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in MPZL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
883,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000158373. Does perturbing NIT1 lead to a significant change in ENSG00000158373 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H2BD. Does perturbing NIT1 lead to a significant change in HIST1H2BD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is quantified. Does this perturbation result in a significant change in ENSG00000116871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is measured. Determine whether ENSG00000116871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000143162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CREG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3093,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000105939 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105939 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2020,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000168140 is measured. Does this perturbation cause a significant change in ENSG00000168140 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of VASN is measured. Does this perturbation cause a significant change in VASN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1938,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000116871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1078,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
3148,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000117139 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117139 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor KDM5B expression. Decide whether this perturbation leads to a significant alteration in KDM5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1083,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000103241 expression is observed. Does this perturbation lead to a significant difference in ENSG00000103241 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000129514. Does perturbing FOXA1 lead to a significant change in ENSG00000129514 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FOXA1. Does perturbing FOXA1 lead to a significant change in FOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000099625 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of C19orf26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000183770. Does perturbing FOXL2 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FOXL2. Does perturbing FOXL2 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000162878. Does this perturbation cause a significant change in ENSG00000162878 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of PKDCC. Does this perturbation cause a significant change in PKDCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000105939 expression is measured. Determine whether ENSG00000105939 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000104894 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000237330 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RNF223 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000118777 expression is measured. Determine whether ENSG00000118777 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ABCG2 expression is measured. Determine whether ABCG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000184697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CLDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
870,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
3,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000134321 expression is observed. Does this perturbation lead to a significant difference in ENSG00000134321 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RSAD2 expression is observed. Does this perturbation lead to a significant difference in RSAD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2038,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000114315 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000114315 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor HES1 expression. Decide whether this perturbation leads to a significant alteration in HES1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000030110. Does this perturbation cause a significant change in ENSG00000030110 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
3115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
3143,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000117139 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117139 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and KDM5B expression is observed. Does this perturbation lead to a significant difference in KDM5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is quantified. Does this perturbation result in a significant change in ENSG00000174498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000186051 is measured. Determine whether ENSG00000186051 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of TAL2 is measured. Determine whether TAL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1378,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000117091 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117091 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CD48 expression. Decide whether this perturbation leads to a significant alteration in CD48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2663,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000120738 expression is observed. Does this perturbation lead to a significant difference in ENSG00000120738 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and EGR1 expression is observed. Does this perturbation lead to a significant difference in EGR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000162878. Does perturbing CKS1B lead to a significant change in ENSG00000162878 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of PKDCC. Does perturbing CKS1B lead to a significant change in PKDCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000004939 is measured. Determine whether ENSG00000004939 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of SLC4A1 is measured. Determine whether SLC4A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
40,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000153012. Does perturbing CEBPB lead to a significant change in ENSG00000153012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of LGI2. Does perturbing CEBPB lead to a significant change in LGI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000266976 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AC079466.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000254614. Does perturbing SLC4A1 lead to a significant change in ENSG00000254614 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AP003068.23. Does perturbing SLC4A1 lead to a significant change in AP003068.23 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000114315. Does this perturbation cause a significant change in ENSG00000114315 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of HES1. Does this perturbation cause a significant change in HES1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000117091 expression is measured. Determine whether ENSG00000117091 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CD48 expression is measured. Determine whether CD48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2423,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000237330 expression is quantified. Does this perturbation result in a significant change in ENSG00000237330 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RNF223 expression is quantified. Does this perturbation result in a significant change in RNF223 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000137841 expression is quantified. Does this perturbation result in a significant change in ENSG00000137841 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PLCB2 expression is quantified. Does this perturbation result in a significant change in PLCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000182871 expression is quantified. Does this perturbation result in a significant change in ENSG00000182871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and COL18A1 expression is quantified. Does this perturbation result in a significant change in COL18A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000071967 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in CYBRD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000153012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of LGI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000188483 expression is measured. Determine whether ENSG00000188483 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and IER5L expression is measured. Determine whether IER5L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000198758. Does perturbing HNF4A lead to a significant change in ENSG00000198758 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of EPS8L3. Does perturbing HNF4A lead to a significant change in EPS8L3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
473,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000158517 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158517 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and NCF1 expression is observed. Does this perturbation lead to a significant difference in NCF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2433,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000079102 expression is observed. Does this perturbation lead to a significant difference in ENSG00000079102 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and RUNX1T1 expression is observed. Does this perturbation lead to a significant difference in RUNX1T1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1458,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000090382 expression is measured. Determine whether ENSG00000090382 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LYZ expression is measured. Determine whether LYZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
3046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2248,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000133317. Does this perturbation cause a significant change in ENSG00000133317 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000170689. Does this perturbation cause a significant change in ENSG00000170689 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of HOXB9. Does this perturbation cause a significant change in HOXB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000256713 is measured. Determine whether ENSG00000256713 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PGA5 is measured. Determine whether PGA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000174498. Does perturbing IGDCC3 lead to a significant change in ENSG00000174498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of IGDCC3. Does perturbing IGDCC3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
3077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000115844 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of DLX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1260,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000101076 is measured. Does this perturbation cause a significant change in ENSG00000101076 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of HNF4A is measured. Does this perturbation cause a significant change in HNF4A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
353,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
13,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000106546 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106546 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and AHR expression is observed. Does this perturbation lead to a significant difference in AHR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is quantified. Does this perturbation result in a significant change in ENSG00000079102 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is quantified. Does this perturbation result in a significant change in RUNX1T1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2410,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163499 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of CRYBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000163520 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of FBLN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000170180 is measured. Determine whether ENSG00000170180 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPA is measured. Determine whether GYPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
42,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Determine whether ENSG00000169410 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Determine whether PTPN9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1703,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000272211 expression is observed. Does this perturbation lead to a significant difference in ENSG00000272211 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and RP11-347P5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-347P5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000104903 is measured. Determine whether ENSG00000104903 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of LYL1 is measured. Determine whether LYL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000069482. Does perturbing MAP2K3 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of GAL. Does perturbing MAP2K3 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
7,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000134321 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RSAD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2488,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000105697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HAMP expression. Decide whether this perturbation leads to a significant alteration in HAMP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000279529 expression is quantified. Does this perturbation result in a significant change in ENSG00000279529 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and CTD-3222D19.8 expression is quantified. Does this perturbation result in a significant change in CTD-3222D19.8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."