,question,answer,question_new
1626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1243,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000135837 expression is measured. Determine whether ENSG00000135837 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and CEP350 expression is measured. Determine whether CEP350 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000130766. Does perturbing BHLHE40 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of SESN2. Does perturbing BHLHE40 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
8,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
790,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000158869. Does perturbing SEC61G lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of FCER1G. Does perturbing SEC61G lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2053,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000070785 expression is measured. Determine whether ENSG00000070785 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and EIF2B3 expression is measured. Determine whether EIF2B3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
98,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
88,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1353,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1750,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
290,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000198771 is measured. Does this perturbation cause a significant change in ENSG00000198771 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1000,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2173,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2340,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
903,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000116761 is measured. Determine whether ENSG00000116761 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CTH is measured. Determine whether CTH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2038,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1678,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1198,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1818,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1303,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1398,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000135838 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in NPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
988,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000197989. Does perturbing STT3A lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of SNHG12. Does perturbing STT3A lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000188672. Does perturbing SLC35B1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of RHCE. Does perturbing SLC35B1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000169442. Does perturbing STT3A lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of CD52. Does perturbing STT3A lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000070785. Does this perturbation cause a significant change in ENSG00000070785 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of EIF2B3. Does this perturbation cause a significant change in EIF2B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
600,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2423,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
523,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000070785 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of EIF2B3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1430,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1840,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2420,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1940,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
238,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
64,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
73,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
248,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1888,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1040,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1520,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000198492. Does perturbing SYVN1 lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of YTHDF2. Does perturbing SYVN1 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
853,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of ENSG00000158869. Does perturbing HSPA9 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FCER1G. Does perturbing HSPA9 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2093,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
303,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000117318 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117318 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000016490. Does perturbing UFL1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of CLCA1. Does perturbing UFL1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000135842 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of FAM129A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1698,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
843,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1843,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
758,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2098,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000070785. Does perturbing EIF2B3 lead to a significant change in ENSG00000070785 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of EIF2B3. Does perturbing EIF2B3 lead to a significant change in EIF2B3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1010,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2563,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
253,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000162511 is measured. Determine whether ENSG00000162511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of LAPTM5 is measured. Determine whether LAPTM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2458,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1743,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2298,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
34,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000235169 is measured. Determine whether ENSG00000235169 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SMIM1 is measured. Determine whether SMIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000135842. Does this perturbation cause a significant change in ENSG00000135842 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of FAM129A. Does this perturbation cause a significant change in FAM129A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000198756. Does perturbing IARS2 lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of COLGALT2. Does perturbing IARS2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1703,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2533,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000188672. Does perturbing P4HB lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RHCE. Does perturbing P4HB lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
890,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
150,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1038,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
998,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000169442. Does perturbing FECH lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of CD52. Does perturbing FECH lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ENSG00000169442. Does perturbing TMEM167A lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CD52. Does perturbing TMEM167A lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000227533. Does this perturbation cause a significant change in ENSG00000227533 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ENSG00000116761. Does perturbing ZNF326 lead to a significant change in ENSG00000116761 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CTH. Does perturbing ZNF326 lead to a significant change in CTH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
938,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000162511 expression is quantified. Does this perturbation result in a significant change in ENSG00000162511 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and LAPTM5 expression is quantified. Does this perturbation result in a significant change in LAPTM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1893,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1053,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1640,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
483,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
51,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000117289. Does perturbing AMIGO3 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of TXNIP. Does perturbing AMIGO3 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2553,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000162664 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162664 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ZNF326 expression is observed. Does this perturbation lead to a significant difference in ZNF326 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1378,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
25,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1133,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
35,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2520,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000117289. Does perturbing SEC61G lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TXNIP. Does perturbing SEC61G lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2270,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
39,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
178,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1320,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000092621. Does perturbing EIF2B3 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of PHGDH. Does perturbing EIF2B3 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
420,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1180,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000130766. Does perturbing DDIT3 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of SESN2. Does perturbing DDIT3 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1098,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
550,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2373,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
11,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000142669. Does perturbing AARS lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of SH3BGRL3. Does perturbing AARS lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2400,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000197989. Does perturbing OST4 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of SNHG12. Does perturbing OST4 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1798,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
663,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000070785 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070785 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and EIF2B3 expression is observed. Does this perturbation lead to a significant difference in EIF2B3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2503,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
670,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2363,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000158869. Does perturbing IARS2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of FCER1G. Does perturbing IARS2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2108,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2393,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000116761 is measured. Determine whether ENSG00000116761 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CTH is measured. Determine whether CTH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1583,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2088,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1613,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2203,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000177954. Does perturbing DDIT3 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of RPS27. Does perturbing DDIT3 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
60,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1603,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ENSG00000244038 expression is quantified. Does this perturbation result in a significant change in ENSG00000244038 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and DDOST expression is quantified. Does this perturbation result in a significant change in DDOST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000016490. Does perturbing IER3IP1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of CLCA1. Does perturbing IER3IP1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2230,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
173,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000188672. Does perturbing DDOST lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RHCE. Does perturbing DDOST lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
308,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000117318 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117318 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
763,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000198771 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000198756. Does perturbing EIF2S1 lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of COLGALT2. Does perturbing EIF2S1 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000092621. Does perturbing TIMM23 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of PHGDH. Does perturbing TIMM23 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000159388. Does perturbing COPZ1 lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of BTG2. Does perturbing COPZ1 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2460,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1470,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000159352 is measured. Does this perturbation cause a significant change in ENSG00000159352 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of PSMD4 is measured. Does this perturbation cause a significant change in PSMD4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
488,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000169442. Does perturbing UFL1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of CD52. Does perturbing UFL1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1483,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000177954. Does perturbing GMPPB lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of RPS27. Does perturbing GMPPB lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2540,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000116761. Does perturbing CREB1 lead to a significant change in ENSG00000116761 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CTH. Does perturbing CREB1 lead to a significant change in CTH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1783,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
18,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000117289. Does perturbing SEC61A1 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of TXNIP. Does perturbing SEC61A1 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1080,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000158869. Does perturbing P4HB lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of FCER1G. Does perturbing P4HB lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000235169 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SMIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
270,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000135838 is measured. Does this perturbation cause a significant change in ENSG00000135838 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of NPL is measured. Does this perturbation cause a significant change in NPL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000169442. Does perturbing SEC63 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CD52. Does perturbing SEC63 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1573,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1793,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
100,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1873,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
29,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
63,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000198492. Does perturbing SRPRB lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of YTHDF2. Does perturbing SRPRB lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
208,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000227533 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000227533 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000143333. Does perturbing DDIT3 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of RGS16. Does perturbing DDIT3 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000198492. Does perturbing PDIA6 lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of YTHDF2. Does perturbing PDIA6 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
21,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000143226. Does perturbing AARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of FCGR2A. Does perturbing AARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
480,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000244038 is measured. Does this perturbation cause a significant change in ENSG00000244038 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of DDOST is measured. Does this perturbation cause a significant change in DDOST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2143,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
838,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000169442. Does perturbing SLC39A7 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of CD52. Does perturbing SLC39A7 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2223,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1668,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000162511 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LAPTM5 expression. Decide whether this perturbation leads to a significant alteration in LAPTM5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000188672. Does perturbing GMPPB lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of RHCE. Does perturbing GMPPB lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000198771 expression is measured. Determine whether ENSG00000198771 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2008,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1740,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ENSG00000127125. Does perturbing TTI2 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PPCS. Does perturbing TTI2 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1608,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000158869. Does perturbing STT3A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of FCER1G. Does perturbing STT3A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
433,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000163191 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1708,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2413,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
528,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1418,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000016490. Does perturbing DDRGK1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CLCA1. Does perturbing DDRGK1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1030,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1540,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
300,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000117318 is measured. Does this perturbation cause a significant change in ENSG00000117318 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
623,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
828,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
388,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000158869. Does perturbing HSPA5 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of FCER1G. Does perturbing HSPA5 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000197989. Does perturbing FECH lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of SNHG12. Does perturbing FECH lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ENSG00000188672. Does perturbing TTI2 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RHCE. Does perturbing TTI2 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1473,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000159352 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159352 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and PSMD4 expression is observed. Does this perturbation lead to a significant difference in PSMD4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000177954. Does perturbing MRGBP lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RPS27. Does perturbing MRGBP lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000162511. Does perturbing ASCC3 lead to a significant change in ENSG00000162511 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of LAPTM5. Does perturbing ASCC3 lead to a significant change in LAPTM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
873,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
96,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
38,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
868,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
463,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
5,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000070785 is measured. Determine whether ENSG00000070785 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of EIF2B3 is measured. Determine whether EIF2B3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1373,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
880,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000197989. Does perturbing UFM1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SNHG12. Does perturbing UFM1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
693,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000169442. Does perturbing SCYL1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of CD52. Does perturbing SCYL1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000162664. Does this perturbation cause a significant change in ENSG00000162664 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ZNF326. Does this perturbation cause a significant change in ZNF326 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1138,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
84,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
44,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000092621. Does perturbing SLMO2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PHGDH. Does perturbing SLMO2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000158869. Does perturbing SLC35B1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of FCER1G. Does perturbing SLC35B1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
703,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2320,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1813,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1338,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1488,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000188672. Does perturbing SYVN1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of RHCE. Does perturbing SYVN1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1070,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
583,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
62,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1238,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000188290 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188290 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor HES4 expression. Decide whether this perturbation leads to a significant alteration in HES4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1093,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2208,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
438,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
943,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1903,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1018,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000235169. Does perturbing MTHFD1 lead to a significant change in ENSG00000235169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SMIM1. Does perturbing MTHFD1 lead to a significant change in SMIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1753,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1250,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1988,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2300,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
570,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1648,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2140,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000135842 is measured. Determine whether ENSG00000135842 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of FAM129A is measured. Determine whether FAM129A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2118,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1088,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2050,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2330,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
748,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
92,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
83,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
653,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
560,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000158869. Does perturbing SRPR lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of FCER1G. Does perturbing SRPR lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1253,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000188672. Does perturbing MTHFD1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RHCE. Does perturbing MTHFD1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2513,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000135837 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135837 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and CEP350 expression is observed. Does this perturbation lead to a significant difference in CEP350 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000135838. Does this perturbation cause a significant change in ENSG00000135838 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of NPL. Does this perturbation cause a significant change in NPL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000092621. Does perturbing SARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHGDH. Does perturbing SARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000117289. Does perturbing IDH3A lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TXNIP. Does perturbing IDH3A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000188672. Does perturbing OST4 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of RHCE. Does perturbing OST4 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1808,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000227533 expression is measured. Determine whether ENSG00000227533 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2548,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000162664 expression is measured. Determine whether ENSG00000162664 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ZNF326 expression is measured. Determine whether ZNF326 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000159352 expression is quantified. Does this perturbation result in a significant change in ENSG00000159352 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and PSMD4 expression is quantified. Does this perturbation result in a significant change in PSMD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
310,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
588,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000198771. Does this perturbation cause a significant change in ENSG00000198771 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
398,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1330,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1150,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000188672. Does perturbing CCND3 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RHCE. Does perturbing CCND3 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2380,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
973,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2133,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1848,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1503,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
620,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000169442. Does perturbing SPCS2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CD52. Does perturbing SPCS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
33,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2430,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
858,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000198771. Does this perturbation cause a significant change in ENSG00000198771 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000143226. Does perturbing HARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of FCGR2A. Does perturbing HARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1200,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000177954. Does perturbing GNPNAT1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RPS27. Does perturbing GNPNAT1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000163386 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NBPF10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
393,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1420,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2493,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000163386 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163386 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NBPF10 expression is observed. Does this perturbation lead to a significant difference in NBPF10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
580,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000158869. Does perturbing SEC61A1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of FCER1G. Does perturbing SEC61A1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1960,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1890,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2188,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
633,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
330,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2040,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000016490. Does perturbing HYOU1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of CLCA1. Does perturbing HYOU1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1478,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000159352 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159352 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor PSMD4 expression. Decide whether this perturbation leads to a significant alteration in PSMD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2428,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of ENSG00000227533 is measured. Does this perturbation cause a significant change in ENSG00000227533 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1898,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1233,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000188290 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188290 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and HES4 expression is observed. Does this perturbation lead to a significant difference in HES4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1140,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000188290 expression is quantified. Does this perturbation result in a significant change in ENSG00000188290 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and HES4 expression is quantified. Does this perturbation result in a significant change in HES4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000142669. Does perturbing COPZ1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of SH3BGRL3. Does perturbing COPZ1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
743,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1083,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
138,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000135842 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in FAM129A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
958,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
850,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
870,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1363,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000135838 is measured. Determine whether ENSG00000135838 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of NPL is measured. Determine whether NPL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000016490. Does perturbing DARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of CLCA1. Does perturbing DARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
820,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000158869. Does perturbing SLMO2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FCER1G. Does perturbing SLMO2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000158869. Does perturbing UFM1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FCER1G. Does perturbing UFM1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1760,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
513,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
568,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1548,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000169442. Does perturbing PDIA6 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of CD52. Does perturbing PDIA6 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
90,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
3,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1778,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
898,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1313,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000198771 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198771 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2488,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
698,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2190,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1370,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1453,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
418,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1410,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1833,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000197989. Does perturbing SRP68 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SNHG12. Does perturbing SRP68 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2020,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000169442. Does perturbing SYVN1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of CD52. Does perturbing SYVN1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
370,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000116761 is measured. Does this perturbation cause a significant change in ENSG00000116761 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CTH is measured. Does this perturbation cause a significant change in CTH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000135837 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in CEP350 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
710,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
888,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1963,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
313,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2348,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
128,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000169442. Does perturbing DERL2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CD52. Does perturbing DERL2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
66,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2378,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1588,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1993,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1110,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000177954. Does perturbing SEL1L lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RPS27. Does perturbing SEL1L lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
58,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
283,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1580,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1860,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000116761 expression is quantified. Does this perturbation result in a significant change in ENSG00000116761 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CTH expression is quantified. Does this perturbation result in a significant change in CTH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
74,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1870,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
773,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
613,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
20,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
590,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000244038 is measured. Does this perturbation cause a significant change in ENSG00000244038 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of DDOST is measured. Does this perturbation cause a significant change in DDOST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1230,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000188290 is measured. Does this perturbation cause a significant change in ENSG00000188290 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of HES4 is measured. Does this perturbation cause a significant change in HES4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
93,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000197989. Does perturbing MANF lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of SNHG12. Does perturbing MANF lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000158869. Does perturbing SEC63 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of FCER1G. Does perturbing SEC63 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
643,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000177954. Does perturbing SPCS2 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RPS27. Does perturbing SPCS2 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2313,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1248,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1333,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000143226. Does perturbing EIF2B2 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FCGR2A. Does perturbing EIF2B2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
133,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1173,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
103,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1538,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000163386. Does this perturbation cause a significant change in ENSG00000163386 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NBPF10. Does this perturbation cause a significant change in NBPF10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2290,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000235169 expression is quantified. Does this perturbation result in a significant change in ENSG00000235169 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SMIM1 expression is quantified. Does this perturbation result in a significant change in SMIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
933,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1293,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000235169 expression is observed. Does this perturbation lead to a significant difference in ENSG00000235169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SMIM1 expression is observed. Does this perturbation lead to a significant difference in SMIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000197989. Does perturbing IDH3A lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SNHG12. Does perturbing IDH3A lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000135838 expression is quantified. Does this perturbation result in a significant change in ENSG00000135838 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and NPL expression is quantified. Does this perturbation result in a significant change in NPL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
14,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
89,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
728,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000092621. Does perturbing DNAJC19 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PHGDH. Does perturbing DNAJC19 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
453,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
79,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
120,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2490,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000163386 is measured. Does this perturbation cause a significant change in ENSG00000163386 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NBPF10 is measured. Does this perturbation cause a significant change in NBPF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
360,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1530,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2138,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000163386 expression is measured. Determine whether ENSG00000163386 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NBPF10 expression is measured. Determine whether NBPF10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000169442. Does perturbing SLC35B1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of CD52. Does perturbing SLC35B1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
940,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
860,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1578,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1950,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2028,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1758,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000197989. Does perturbing SEL1L lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of SNHG12. Does perturbing SEL1L lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000227533. Does perturbing CAD lead to a significant change in ENSG00000227533 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SLC2A1-AS1. Does perturbing CAD lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000143333. Does perturbing CREB1 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RGS16. Does perturbing CREB1 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000162511 expression is quantified. Does this perturbation result in a significant change in ENSG00000162511 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LAPTM5 expression is quantified. Does this perturbation result in a significant change in LAPTM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1318,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000198771 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198771 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000092621. Does perturbing EIF2S1 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of PHGDH. Does perturbing EIF2S1 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000031698 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in SARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000235169 expression is quantified. Does this perturbation result in a significant change in ENSG00000235169 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM1 expression is quantified. Does this perturbation result in a significant change in SMIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2350,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2550,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000162664 is measured. Does this perturbation cause a significant change in ENSG00000162664 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ZNF326 is measured. Does this perturbation cause a significant change in ZNF326 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
508,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000117318 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
358,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000142669. Does perturbing IER3IP1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of SH3BGRL3. Does perturbing IER3IP1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1863,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000143226. Does perturbing SLMO2 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FCGR2A. Does perturbing SLMO2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000163191 expression is measured. Determine whether ENSG00000163191 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000092621. Does perturbing TIMM44 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PHGDH. Does perturbing TIMM44 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2148,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2370,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1428,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
228,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1563,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
593,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1823,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000169442. Does perturbing TELO2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CD52. Does perturbing TELO2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000092621. Does perturbing SAMM50 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of PHGDH. Does perturbing SAMM50 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
690,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000159352 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in PSMD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
340,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2530,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000162511 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LAPTM5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000244038 expression is quantified. Does this perturbation result in a significant change in ENSG00000244038 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and DDOST expression is quantified. Does this perturbation result in a significant change in DDOST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
113,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000162511 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162511 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and LAPTM5 expression is observed. Does this perturbation lead to a significant difference in LAPTM5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
913,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1773,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1438,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1433,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
680,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1518,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1528,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000117289. Does perturbing CCND3 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of TXNIP. Does perturbing CCND3 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
268,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2470,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
540,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
470,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2018,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000135842. Does perturbing MARS lead to a significant change in ENSG00000135842 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of FAM129A. Does perturbing MARS lead to a significant change in FAM129A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000135837 is measured. Determine whether ENSG00000135837 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of CEP350 is measured. Determine whether CEP350 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1923,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
760,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1643,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
10,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2288,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000117289. Does perturbing YIPF5 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of TXNIP. Does perturbing YIPF5 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000142669. Does perturbing TMED2 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of SH3BGRL3. Does perturbing TMED2 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2473,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000092621. Does perturbing TARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of PHGDH. Does perturbing TARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2058,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000127125. Does perturbing SRPR lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of PPCS. Does perturbing SRPR lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1533,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1570,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2383,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1728,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
71,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of ENSG00000169442. Does perturbing ARHGAP22 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of CD52. Does perturbing ARHGAP22 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
19,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
273,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000135838 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135838 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and NPL expression is observed. Does this perturbation lead to a significant difference in NPL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
76,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000158869. Does perturbing IDH3A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of FCER1G. Does perturbing IDH3A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
91,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000169442. Does perturbing ASCC3 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CD52. Does perturbing ASCC3 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
59,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2468,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000162664 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ZNF326 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1658,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
328,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000016490. Does perturbing DNAJC19 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of CLCA1. Does perturbing DNAJC19 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000198771 expression is quantified. Does this perturbation result in a significant change in ENSG00000198771 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
130,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1380,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1673,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1350,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2043,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
198,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000143333. Does perturbing BHLHE40 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RGS16. Does perturbing BHLHE40 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
258,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
243,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000244038. Does perturbing HSPA5 lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of DDOST. Does perturbing HSPA5 lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
108,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2218,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1128,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
473,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1480,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1060,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000116761 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CTH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
193,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2398,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000163191. Does perturbing QARS lead to a significant change in ENSG00000163191 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of S100A11. Does perturbing QARS lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000092621. Does perturbing IARS2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of PHGDH. Does perturbing IARS2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
363,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000244038. Does perturbing DHDDS lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of DDOST. Does perturbing DHDDS lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000117289. Does perturbing GNPNAT1 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TXNIP. Does perturbing GNPNAT1 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000016490. Does perturbing HARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of CLCA1. Does perturbing HARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
143,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000116761 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CTH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
923,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1600,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000198771 is measured. Determine whether ENSG00000198771 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2078,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000188672. Does perturbing CAD lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RHCE. Does perturbing CAD lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1543,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and ENSG00000031698 expression is quantified. Does this perturbation result in a significant change in ENSG00000031698 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and SARS expression is quantified. Does this perturbation result in a significant change in SARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000127125. Does perturbing GNPNAT1 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of PPCS. Does perturbing GNPNAT1 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1958,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000197989. Does perturbing KCTD16 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of SNHG12. Does perturbing KCTD16 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2408,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
67,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
598,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1113,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
798,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1650,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1108,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1170,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2198,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000177954. Does perturbing DAD1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RPS27. Does perturbing DAD1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000016490. Does perturbing CHERP lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CLCA1. Does perturbing CHERP lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
700,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of ENSG00000016490. Does perturbing SEC61B lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of CLCA1. Does perturbing SEC61B lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000198771 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
683,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000016490. Does perturbing TARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of CLCA1. Does perturbing TARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2368,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000116761 expression is measured. Determine whether ENSG00000116761 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CTH expression is measured. Determine whether CTH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000158869. Does perturbing SOCS1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of FCER1G. Does perturbing SOCS1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
163,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000197989. Does perturbing SRPRB lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of SNHG12. Does perturbing SRPRB lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
233,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000135838. Does perturbing CHERP lead to a significant change in ENSG00000135838 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of NPL. Does perturbing CHERP lead to a significant change in NPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2178,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1568,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2510,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000135837 is measured. Does this perturbation cause a significant change in ENSG00000135837 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of CEP350 is measured. Does this perturbation cause a significant change in CEP350 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000177954. Does perturbing HYOU1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RPS27. Does perturbing HYOU1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1990,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000130766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in SESN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2518,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000135837 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135837 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor CEP350 expression. Decide whether this perturbation leads to a significant alteration in CEP350 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2010,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
440,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000143226. Does perturbing NEDD8 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FCGR2A. Does perturbing NEDD8 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000235169. Does perturbing PSMD4 lead to a significant change in ENSG00000235169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM1. Does perturbing PSMD4 lead to a significant change in SMIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2073,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2030,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000117318. Does perturbing COPB1 lead to a significant change in ENSG00000117318 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ID3. Does perturbing COPB1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1273,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
833,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1368,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
69,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2410,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
350,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1048,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
823,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1153,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000169442. Does perturbing COPB1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CD52. Does perturbing COPB1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1400,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000116761. Does this perturbation cause a significant change in ENSG00000116761 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CTH. Does this perturbation cause a significant change in CTH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1310,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000198771 is measured. Does this perturbation cause a significant change in ENSG00000198771 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2100,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1168,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2303,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1240,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
448,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1900,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of ENSG00000016490. Does perturbing XRN1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of CLCA1. Does perturbing XRN1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
80,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2153,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2083,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
333,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1360,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000163386 is measured. Determine whether ENSG00000163386 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NBPF10 is measured. Determine whether NBPF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2238,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
95,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000142669. Does perturbing DARS lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SH3BGRL3. Does perturbing DARS lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000031698 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of SARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1878,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000158869. Does perturbing SRP68 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of FCER1G. Does perturbing SRP68 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000162511. Does perturbing SEC61A1 lead to a significant change in ENSG00000162511 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LAPTM5. Does perturbing SEC61A1 lead to a significant change in LAPTM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1590,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000031698 is measured. Does this perturbation cause a significant change in ENSG00000031698 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of SARS is measured. Does this perturbation cause a significant change in SARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000163386 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NBPF10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
503,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000235169 expression is measured. Determine whether ENSG00000235169 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SMIM1 expression is measured. Determine whether SMIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of ENSG00000227533 is measured. Determine whether ENSG00000227533 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1560,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
810,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2463,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
720,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1953,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
740,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1463,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2403,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000070785 expression is quantified. Does this perturbation result in a significant change in ENSG00000070785 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and EIF2B3 expression is quantified. Does this perturbation result in a significant change in EIF2B3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
37,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000092621. Does perturbing EIF2B2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PHGDH. Does perturbing EIF2B2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2163,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2328,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000092621. Does perturbing HARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PHGDH. Does perturbing HARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
223,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1270,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000143226. Does perturbing CARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of FCGR2A. Does perturbing CARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000158869. Does perturbing SPCS3 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of FCER1G. Does perturbing SPCS3 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2353,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
990,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2123,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000188672. Does perturbing SOCS1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RHCE. Does perturbing SOCS1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
6,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000016490. Does perturbing PPWD1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CLCA1. Does perturbing PPWD1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000235169 expression is measured. Determine whether ENSG00000235169 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM1 expression is measured. Determine whether SMIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2578,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000116761 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116761 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CTH expression. Decide whether this perturbation leads to a significant alteration in CTH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
68,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1880,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
608,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2273,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1408,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
510,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000135838 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of NPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000197989. Does perturbing DDRGK1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SNHG12. Does perturbing DDRGK1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
203,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000227533 expression is observed. Does this perturbation lead to a significant difference in ENSG00000227533 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2170,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
318,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
15,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000158869. Does perturbing QARS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of FCER1G. Does perturbing QARS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
368,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2068,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1980,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000162511 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LAPTM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1830,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000142669. Does perturbing HSD17B12 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of SH3BGRL3. Does perturbing HSD17B12 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
12,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000117289. Does perturbing SEL1L lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TXNIP. Does perturbing SEL1L lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1393,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000143226. Does perturbing FARSB lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of FCGR2A. Does perturbing FARSB lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
533,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000016490. Does perturbing GBF1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CLCA1. Does perturbing GBF1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1188,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000016490. Does perturbing TELO2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000016490. Does perturbing CCND3 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CLCA1. Does perturbing CCND3 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2023,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
160,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ENSG00000117318. Does this perturbation cause a significant change in ENSG00000117318 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
22,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2263,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000235169 is measured. Determine whether ENSG00000235169 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM1 is measured. Determine whether SMIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1068,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000092621. Does perturbing ATP5B lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of PHGDH. Does perturbing ATP5B lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
4,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
730,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
930,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
460,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
0,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1423,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
818,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2443,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
78,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1558,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000163191 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163191 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
278,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000135838 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135838 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor NPL expression. Decide whether this perturbation leads to a significant alteration in NPL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
458,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000197989. Does perturbing HYOU1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of SNHG12. Does perturbing HYOU1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1630,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1970,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2158,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
770,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
41,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000158869. Does perturbing AMIGO3 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of FCER1G. Does perturbing AMIGO3 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000235169 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2418,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2048,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1713,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
353,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
673,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000198771 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1278,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000198771 expression is quantified. Does this perturbation result in a significant change in ENSG00000198771 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
47,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1663,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000162511 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162511 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LAPTM5 expression is observed. Does this perturbation lead to a significant difference in LAPTM5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2440,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2193,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
190,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000188672. Does perturbing PTDSS1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RHCE. Does perturbing PTDSS1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000162664 is measured. Determine whether ENSG00000162664 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ZNF326 is measured. Determine whether ZNF326 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1828,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
43,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000016490. Does perturbing SAMM50 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of CLCA1. Does perturbing SAMM50 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000064886. Does perturbing BHLHE40 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CHI3L2. Does perturbing BHLHE40 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
578,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
280,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000162511. Does this perturbation cause a significant change in ENSG00000162511 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of LAPTM5. Does this perturbation cause a significant change in LAPTM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2318,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000031698. Does this perturbation cause a significant change in ENSG00000031698 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of SARS. Does this perturbation cause a significant change in SARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1390,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
343,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
900,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000135838 expression is measured. Determine whether ENSG00000135838 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and NPL expression is measured. Determine whether NPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
548,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
153,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000117289. Does perturbing CAD lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TXNIP. Does perturbing CAD lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000235169. Does this perturbation cause a significant change in ENSG00000235169 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SMIM1. Does this perturbation cause a significant change in SMIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1050,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
920,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000031698 is measured. Determine whether ENSG00000031698 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of SARS is measured. Determine whether SARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000163386 expression is quantified. Does this perturbation result in a significant change in ENSG00000163386 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NBPF10 expression is quantified. Does this perturbation result in a significant change in NBPF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1738,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1550,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000163191 is measured. Does this perturbation cause a significant change in ENSG00000163191 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
85,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000169442. Does perturbing MRGBP lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of CD52. Does perturbing MRGBP lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000117289. Does perturbing KCTD16 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of TXNIP. Does perturbing KCTD16 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
26,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000127125. Does perturbing OST4 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of PPCS. Does perturbing OST4 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
86,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1768,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000142669. Does perturbing HSPA5 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SH3BGRL3. Does perturbing HSPA5 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000016490. Does perturbing TMED2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of CLCA1. Does perturbing TMED2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1130,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000135842 expression is quantified. Does this perturbation result in a significant change in ENSG00000135842 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and FAM129A expression is quantified. Does this perturbation result in a significant change in FAM129A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1298,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000235169 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000235169 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SMIM1 expression. Decide whether this perturbation leads to a significant alteration in SMIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2498,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000163386 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163386 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NBPF10 expression. Decide whether this perturbation leads to a significant alteration in NBPF10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2228,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
918,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1790,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ENSG00000143333. Does perturbing ZNF326 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RGS16. Does perturbing ZNF326 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000016490. Does perturbing EIF2B2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of CLCA1. Does perturbing EIF2B2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
413,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000188290. Does this perturbation cause a significant change in ENSG00000188290 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of HES4. Does this perturbation cause a significant change in HES4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1593,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000031698 expression is observed. Does this perturbation lead to a significant difference in ENSG00000031698 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and SARS expression is observed. Does this perturbation lead to a significant difference in SARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
783,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
840,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2433,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2260,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000169442. Does perturbing PTDSS1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of CD52. Does perturbing PTDSS1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
87,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1448,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
708,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000016490. Does perturbing TTI1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of CLCA1. Does perturbing TTI1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1260,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1148,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1653,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1220,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000162511 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of LAPTM5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000142669. Does perturbing DNAJC19 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of SH3BGRL3. Does perturbing DNAJC19 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1043,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000158869. Does perturbing FECH lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of FCER1G. Does perturbing FECH lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
733,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000162511 expression is measured. Determine whether ENSG00000162511 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LAPTM5 expression is measured. Determine whether LAPTM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1858,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000142669. Does perturbing SPCS2 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of SH3BGRL3. Does perturbing SPCS2 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2388,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
408,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000169442. Does perturbing COPZ1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of CD52. Does perturbing COPZ1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1058,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
218,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
928,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1443,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
148,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
563,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1968,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
403,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
788,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000031698 expression is measured. Determine whether ENSG00000031698 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and SARS expression is measured. Determine whether SARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000116761. Does this perturbation cause a significant change in ENSG00000116761 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CTH. Does this perturbation cause a significant change in CTH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000135842 expression is measured. Determine whether ENSG00000135842 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and FAM129A expression is measured. Determine whether FAM129A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1210,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000135842 is measured. Does this perturbation cause a significant change in ENSG00000135842 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of FAM129A is measured. Does this perturbation cause a significant change in FAM129A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2278,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
75,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
948,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
410,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ENSG00000158869. Does perturbing TMEM167A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of FCER1G. Does perturbing TMEM167A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000127125. Does perturbing SRP68 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of PPCS. Does perturbing SRP68 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000117318 expression is measured. Determine whether ENSG00000117318 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
553,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
793,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
688,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2250,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1718,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2558,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000162664 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162664 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ZNF326 expression. Decide whether this perturbation leads to a significant alteration in ZNF326 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000117318 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1440,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000016490. Does perturbing UFM1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CLCA1. Does perturbing UFM1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1013,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000135837. Does this perturbation cause a significant change in ENSG00000135837 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of CEP350. Does this perturbation cause a significant change in CEP350 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1403,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1523,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1670,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2323,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1160,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2150,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1413,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000188290 is measured. Determine whether ENSG00000188290 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of HES4 is measured. Determine whether HES4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
70,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2283,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1358,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000169442. Does perturbing HSD17B12 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CD52. Does perturbing HSD17B12 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000169442. Does perturbing TMED2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of CD52. Does perturbing TMED2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1918,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000198771 expression is measured. Determine whether ENSG00000198771 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
170,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
750,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000092621. Does perturbing AARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of PHGDH. Does perturbing AARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000197989. Does perturbing MRPL39 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of SNHG12. Does perturbing MRPL39 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1943,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
813,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1553,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000163191 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163191 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2003,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2110,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2358,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
53,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1450,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000158869. Does perturbing GBF1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of FCER1G. Does perturbing GBF1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
168,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
530,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000198771 is measured. Determine whether ENSG00000198771 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
803,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000142669. Does perturbing COPB1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SH3BGRL3. Does perturbing COPB1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000235169 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SMIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
373,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000116761 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116761 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CTH expression is observed. Does this perturbation lead to a significant difference in CTH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1103,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
81,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of ENSG00000197989. Does perturbing ARHGAP22 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SNHG12. Does perturbing ARHGAP22 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1203,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000159352. Does perturbing PSMD4 lead to a significant change in ENSG00000159352 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of PSMD4. Does perturbing PSMD4 lead to a significant change in PSMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
650,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
678,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1693,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1908,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
31,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000177954. Does perturbing AMIGO3 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RPS27. Does perturbing AMIGO3 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000188672. Does perturbing SLC39A7 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of RHCE. Does perturbing SLC39A7 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
808,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1810,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
558,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000177954. Does perturbing SRP72 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of RPS27. Does perturbing SRP72 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000016490. Does perturbing YIPF5 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CLCA1. Does perturbing YIPF5 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
518,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000117289. Does perturbing MARS lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of TXNIP. Does perturbing MARS lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1973,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1100,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2560,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
94,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1023,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1748,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
960,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000092621. Does perturbing QARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of PHGDH. Does perturbing QARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of ENSG00000016490. Does perturbing EIF2B4 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of CLCA1. Does perturbing EIF2B4 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
980,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
46,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000227533 expression is quantified. Does this perturbation result in a significant change in ENSG00000227533 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000197989. Does perturbing DERL2 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SNHG12. Does perturbing DERL2 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
640,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1998,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
400,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
30,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000143226. Does perturbing SARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of FCGR2A. Does perturbing SARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1620,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
54,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
978,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
423,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
40,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000188672. Does perturbing PSMD4 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of RHCE. Does perturbing PSMD4 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1930,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1500,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1820,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1340,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000197989. Does perturbing GMPPB lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of SNHG12. Does perturbing GMPPB lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1513,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2450,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
140,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
213,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2033,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
668,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000070785 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070785 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor EIF2B3 expression. Decide whether this perturbation leads to a significant alteration in EIF2B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000016490. Does perturbing FARSB lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CLCA1. Does perturbing FARSB lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2390,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2253,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1328,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1458,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000197989. Does perturbing PDIA6 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SNHG12. Does perturbing PDIA6 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ENSG00000162511 expression is measured. Determine whether ENSG00000162511 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and LAPTM5 expression is measured. Determine whether LAPTM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1838,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
953,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000197989. Does perturbing ATP5B lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SNHG12. Does perturbing ATP5B lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000169442. Does perturbing PPWD1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CD52. Does perturbing PPWD1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2183,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1213,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000135842 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135842 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and FAM129A expression is observed. Does this perturbation lead to a significant difference in FAM129A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
13,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2568,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000143333. Does perturbing EIF2S1 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RGS16. Does perturbing EIF2S1 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2338,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2180,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
380,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1508,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
983,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ENSG00000162664 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ZNF326 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000159352 expression is measured. Determine whether ENSG00000159352 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and PSMD4 expression is measured. Determine whether PSMD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
478,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2438,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000070785 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in EIF2B3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2343,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
390,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000197989. Does perturbing SRP72 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SNHG12. Does perturbing SRP72 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1493,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000235169 expression is observed. Does this perturbation lead to a significant difference in ENSG00000235169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM1 expression is observed. Does this perturbation lead to a significant difference in SMIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1460,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
7,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000177954. Does perturbing MRPL39 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RPS27. Does perturbing MRPL39 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of ENSG00000197989. Does perturbing SEC61B lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SNHG12. Does perturbing SEC61B lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
118,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000162511 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor LAPTM5 expression. Decide whether this perturbation leads to a significant alteration in LAPTM5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
263,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
500,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000092621. Does perturbing CARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of PHGDH. Does perturbing CARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
28,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
378,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000116761 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116761 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CTH expression. Decide whether this perturbation leads to a significant alteration in CTH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000159352 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of PSMD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000198771. Does perturbing CHERP lead to a significant change in ENSG00000198771 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RCSD1. Does perturbing CHERP lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1383,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
520,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1228,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1258,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2128,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1978,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000162511 is measured. Determine whether ENSG00000162511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LAPTM5 is measured. Determine whether LAPTM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1020,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
610,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
753,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000169442. Does perturbing NEDD8 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of CD52. Does perturbing NEDD8 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
618,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2500,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1660,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000162511 is measured. Does this perturbation cause a significant change in ENSG00000162511 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LAPTM5 is measured. Does this perturbation cause a significant change in LAPTM5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000188290 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in HES4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
55,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
963,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1120,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
82,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000130766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in SESN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2538,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1280,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
52,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000227533 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000143333. Does perturbing EIF2B3 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of RGS16. Does perturbing EIF2B3 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000142669. Does perturbing ASCC3 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SH3BGRL3. Does perturbing ASCC3 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
658,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000142669. Does perturbing SLC39A7 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SH3BGRL3. Does perturbing SLC39A7 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1510,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000244038. Does perturbing DDOST lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of DDOST. Does perturbing DDOST lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
123,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
183,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000163191 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1883,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1683,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2543,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000142669. Does perturbing SPCS3 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of SH3BGRL3. Does perturbing SPCS3 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000177606. Does perturbing MARS lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of JUN. Does perturbing MARS lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1323,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1610,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2528,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1788,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
778,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1803,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1263,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
573,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000016490. Does perturbing DHDDS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLCA1. Does perturbing DHDDS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
97,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2243,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000188290 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of HES4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2200,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
883,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1143,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
490,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
638,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000158869. Does perturbing ATP5B lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of FCER1G. Does perturbing ATP5B lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
158,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
293,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000198771 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198771 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1498,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000235169 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000235169 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM1 expression. Decide whether this perturbation leads to a significant alteration in SMIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000197989. Does perturbing TMED10 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SNHG12. Does perturbing TMED10 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
493,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2120,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000169442. Does perturbing SPCS3 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CD52. Does perturbing SPCS3 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000135837 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of CEP350 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1118,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000158869. Does perturbing IER3IP1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of FCER1G. Does perturbing IER3IP1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1948,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
863,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1193,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1078,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
628,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000016490. Does perturbing TMED10 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of CLCA1. Does perturbing TMED10 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
893,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1300,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
538,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000169442. Does perturbing TTI1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of CD52. Does perturbing TTI1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of ENSG00000163386. Does perturbing XRN1 lead to a significant change in ENSG00000163386 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NBPF10. Does perturbing XRN1 lead to a significant change in NBPF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1623,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000197989. Does perturbing PTDSS1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of SNHG12. Does perturbing PTDSS1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
430,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
320,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
800,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000169442. Does perturbing P4HB lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CD52. Does perturbing P4HB lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2233,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2248,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1290,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000235169 is measured. Does this perturbation cause a significant change in ENSG00000235169 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SMIM1 is measured. Does this perturbation cause a significant change in SMIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
718,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000163191 expression is quantified. Does this perturbation result in a significant change in ENSG00000163191 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000158869. Does perturbing DHDDS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of FCER1G. Does perturbing DHDDS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
23,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000016490. Does perturbing DAD1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of CLCA1. Does perturbing DAD1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
110,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000162511 is measured. Does this perturbation cause a significant change in ENSG00000162511 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of LAPTM5 is measured. Does this perturbation cause a significant change in LAPTM5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
450,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000162511 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in LAPTM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000143226. Does perturbing SAMM50 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of FCGR2A. Does perturbing SAMM50 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
950,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000135837 expression is quantified. Does this perturbation result in a significant change in ENSG00000135837 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and CEP350 expression is quantified. Does this perturbation result in a significant change in CEP350 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000116761 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CTH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2523,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1208,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000188672. Does perturbing TELO2 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of RHCE. Does perturbing TELO2 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000188290 expression is measured. Determine whether ENSG00000188290 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and HES4 expression is measured. Determine whether HES4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1983,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2508,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ENSG00000163191. Does this perturbation cause a significant change in ENSG00000163191 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000177954. Does perturbing SOCS1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RPS27. Does perturbing SOCS1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1468,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2293,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000016490. Does perturbing SCYL1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of CLCA1. Does perturbing SCYL1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
72,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2573,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000116761 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116761 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CTH expression is observed. Does this perturbation lead to a significant difference in CTH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2478,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2210,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
428,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
323,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1853,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000158869. Does perturbing DDRGK1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of FCER1G. Does perturbing DDRGK1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
36,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
648,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000169442. Does perturbing TMED10 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of CD52. Does perturbing TMED10 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1028,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1933,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000127125. Does perturbing SRPRB lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of PPCS. Does perturbing SRPRB lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2213,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2453,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000159352. Does this perturbation cause a significant change in ENSG00000159352 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of PSMD4. Does this perturbation cause a significant change in PSMD4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1283,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000117318 is measured. Determine whether ENSG00000117318 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000016490. Does perturbing TIMM44 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of CLCA1. Does perturbing TIMM44 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000116761 expression is quantified. Does this perturbation result in a significant change in ENSG00000116761 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CTH expression is quantified. Does this perturbation result in a significant change in CTH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2013,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2448,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
298,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000198771 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198771 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
260,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
48,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000016490. Does perturbing DDOST lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of CLCA1. Does perturbing DDOST lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000188290. Does perturbing MRGBP lead to a significant change in ENSG00000188290 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of HES4. Does perturbing MRGBP lead to a significant change in HES4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2333,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000142669. Does perturbing NEDD8 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of SH3BGRL3. Does perturbing NEDD8 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1223,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
780,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
630,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2280,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000143226. Does perturbing HSD17B12 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of FCGR2A. Does perturbing HSD17B12 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1688,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1008,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1733,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000235169 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1913,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000162664 expression is quantified. Does this perturbation result in a significant change in ENSG00000162664 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ZNF326 expression is quantified. Does this perturbation result in a significant change in ZNF326 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
338,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1618,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
603,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1490,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000235169 is measured. Does this perturbation cause a significant change in ENSG00000235169 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM1 is measured. Does this perturbation cause a significant change in SMIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000158869. Does perturbing UFL1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of FCER1G. Does perturbing UFL1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000092621. Does perturbing FARSB lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of PHGDH. Does perturbing FARSB lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2168,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
188,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1343,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000235169. Does this perturbation cause a significant change in ENSG00000235169 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM1. Does this perturbation cause a significant change in SMIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
65,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1163,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
45,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
16,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000158869. Does perturbing DERL2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of FCER1G. Does perturbing DERL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000198771 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000197989. Does perturbing GBF1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SNHG12. Does perturbing GBF1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1868,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1288,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2360,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1628,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1348,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
49,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2268,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2103,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1928,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
908,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000227533 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000162511. Does this perturbation cause a significant change in ENSG00000162511 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LAPTM5. Does this perturbation cause a significant change in LAPTM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000143226. Does perturbing TIMM44 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of FCGR2A. Does perturbing TIMM44 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
468,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000197989. Does perturbing YIPF5 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of SNHG12. Does perturbing YIPF5 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1123,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1178,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1910,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1308,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
32,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000159352 is measured. Determine whether ENSG00000159352 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of PSMD4 is measured. Determine whether PSMD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
443,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
24,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
713,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000169442. Does perturbing KCTD16 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CD52. Does perturbing KCTD16 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
848,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1218,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000135842 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135842 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor FAM129A expression. Decide whether this perturbation leads to a significant alteration in FAM129A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2258,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1003,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1920,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000163191 is measured. Determine whether ENSG00000163191 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
910,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1633,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000117318 expression is quantified. Does this perturbation result in a significant change in ENSG00000117318 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000092621. Does perturbing DARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PHGDH. Does perturbing DARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000198771. Does perturbing MTHFD1 lead to a significant change in ENSG00000198771 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RCSD1. Does perturbing MTHFD1 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000158869. Does perturbing MRPL39 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of FCER1G. Does perturbing MRPL39 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1158,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
723,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
288,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
2181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000158869. Does perturbing TARS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of FCER1G. Does perturbing TARS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000159388. Does perturbing PPWD1 lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of BTG2. Does perturbing PPWD1 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1033,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
42,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1090,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
348,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2308,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000016490. Does perturbing TIMM23 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of CLCA1. Does perturbing TIMM23 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2063,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000117289. Does perturbing MANF lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of TXNIP. Does perturbing MANF lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
738,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
1183,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000188672. Does perturbing TTI1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RHCE. Does perturbing TTI1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
993,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
2579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000116761 expression is measured. Determine whether ENSG00000116761 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CTH expression is measured. Determine whether CTH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
2241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000142669. Does perturbing TIMM23 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of SH3BGRL3. Does perturbing TIMM23 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000130766. Does perturbing CREB1 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of SESN2. Does perturbing CREB1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
17,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1938,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'."
2202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
1366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000158869. Does perturbing SCYL1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCER1G. Does perturbing SCYL1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000198756. Does perturbing CARS lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of COLGALT2. Does perturbing CARS lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
1502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
2113,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000127125. Does perturbing MANF lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of PPCS. Does perturbing MANF lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000197989. Does perturbing SEC61G lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of SNHG12. Does perturbing SEC61G lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000197989. Does perturbing DAD1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of SNHG12. Does perturbing DAD1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
2509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000158869. Does perturbing SRP72 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of FCER1G. Does perturbing SRP72 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000197989. Does perturbing SEC63 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of SNHG12. Does perturbing SEC63 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
383,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.
1689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
1591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000031698. Does perturbing SARS lead to a significant change in ENSG00000031698 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of SARS. Does perturbing SARS lead to a significant change in SARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
50,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000197989. Does perturbing SRPR lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SNHG12. Does perturbing SRPR lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
830,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
2522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."
1895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'."
2240,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'."
1856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."
217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'."
2372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of ENSG00000092621. Does perturbing HSPA9 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PHGDH. Does perturbing HSPA9 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'."
1852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'."
1063,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.