[ { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1626 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1243 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000135837 expression is measured. Determine whether ENSG00000135837 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and CEP350 expression is measured. Determine whether CEP350 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2519 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2337 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000130766. Does perturbing BHLHE40 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of SESN2. Does perturbing BHLHE40 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":171 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":885 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1374 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":8 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":709 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1339 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":839 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1547 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1615 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":122 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":790 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000158869. Does perturbing SEC61G lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of FCER1G. Does perturbing SEC61G lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1711 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2053 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1375 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2112 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1635 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":965 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000070785 expression is measured. Determine whether ENSG00000070785 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and EIF2B3 expression is measured. Determine whether EIF2B3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":669 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":98 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":88 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1353 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1750 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":349 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000198771 is measured. Does this perturbation cause a significant change in ENSG00000198771 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":290 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":734 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1000 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1137 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2173 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1177 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1866 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2340 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":903 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1529 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000116761 is measured. Determine whether ENSG00000116761 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of CTH is measured. Determine whether CTH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2576 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2038 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1019 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2436 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":155 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":545 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1678 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":752 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2220 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":265 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1198 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2259 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1818 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2266 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":497 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":912 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":914 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1303 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2037 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2547 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2017 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1587 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":717 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2254 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1398 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000135838 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in NPL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":275 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":988 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000197989. Does perturbing STT3A lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of SNHG12. Does perturbing STT3A lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2111 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":514 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000188672. Does perturbing SLC35B1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of RHCE. Does perturbing SLC35B1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1821 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1975 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1609 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000169442. Does perturbing STT3A lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of CD52. Does perturbing STT3A lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2101 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000070785. Does this perturbation cause a significant change in ENSG00000070785 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of EIF2B3. Does this perturbation cause a significant change in EIF2B3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":664 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":600 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":455 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2277 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1829 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":485 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":897 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2423 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":236 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":523 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2106 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000070785 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of EIF2B3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":667 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1430 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2057 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1134 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1840 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2420 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1940 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":238 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":985 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1419 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1167 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1749 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":575 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2414 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1489 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":64 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1865 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":73 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1136 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":248 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":917 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":584 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2086 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1888 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1040 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":326 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1526 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1520 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":365 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2505 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000198492. Does perturbing SYVN1 lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of YTHDF2. Does perturbing SYVN1 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2141 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":254 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":853 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of ENSG00000158869. Does perturbing HSPA9 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of FCER1G. Does perturbing HSPA9 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1001 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2346 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":416 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2093 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":435 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1907 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":407 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":609 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2309 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1115 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000117318 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117318 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":303 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1564 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1197 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1834 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000016490. Does perturbing UFL1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of CLCA1. Does perturbing UFL1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2441 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1117 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000135842 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of FAM129A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1217 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1698 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":843 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1843 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":758 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":947 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1676 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":102 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":757 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2098 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000070785. Does perturbing EIF2B3 lead to a significant change in ENSG00000070785 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of EIF2B3. Does perturbing EIF2B3 lead to a significant change in EIF2B3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":661 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1010 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":357 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2327 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2563 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":749 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":253 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000162511 is measured. Determine whether ENSG00000162511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of LAPTM5 is measured. Determine whether LAPTM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":116 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2458 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":442 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1743 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2298 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":34 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":412 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000235169 is measured. Determine whether ENSG00000235169 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of SMIM1 is measured. Determine whether SMIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1296 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":196 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2229 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000135842. Does this perturbation cause a significant change in ENSG00000135842 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of FAM129A. Does this perturbation cause a significant change in FAM129A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1214 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1567 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000198756. Does perturbing IARS2 lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of COLGALT2. Does perturbing IARS2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1061 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1979 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1334 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA5 is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":975 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1912 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1703 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2533 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1745 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":539 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1566 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":382 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1425 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000188672. Does perturbing P4HB lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of RHCE. Does perturbing P4HB lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1401 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":890 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1946 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":150 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2046 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1038 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":998 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1036 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1986 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1646 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000169442. Does perturbing FECH lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of CD52. Does perturbing FECH lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":781 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":627 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":889 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ENSG00000169442. Does perturbing TMEM167A lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CD52. Does perturbing TMEM167A lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2361 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000227533. Does this perturbation cause a significant change in ENSG00000227533 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":204 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1945 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ENSG00000116761. Does perturbing ZNF326 lead to a significant change in ENSG00000116761 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of CTH. Does perturbing ZNF326 lead to a significant change in CTH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2571 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":938 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000162511 expression is quantified. Does this perturbation result in a significant change in ENSG00000162511 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and LAPTM5 expression is quantified. Does this perturbation result in a significant change in LAPTM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":112 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2124 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1893 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1815 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":969 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1053 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":577 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":134 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1435 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2359 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1964 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1640 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":126 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":427 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2082 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1327 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1354 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2059 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2155 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":483 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2354 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2142 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000117289. Does perturbing AMIGO3 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of TXNIP. Does perturbing AMIGO3 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":51 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1326 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000162664 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162664 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ZNF326 expression is observed. Does this perturbation lead to a significant difference in ZNF326 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2553 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1574 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":629 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1257 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2064 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":327 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1378 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":226 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":25 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2196 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":249 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1746 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1133 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2149 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":35 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2520 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000117289. Does perturbing SEC61G lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of TXNIP. Does perturbing SEC61G lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1731 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2094 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1459 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2270 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2504 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":586 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1826 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2102 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":537 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1254 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":39 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":682 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":178 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1506 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1320 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1952 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000092621. Does perturbing EIF2B3 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of PHGDH. Does perturbing EIF2B3 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":671 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":420 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":316 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1180 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2435 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1356 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000130766. Does perturbing DDIT3 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of SESN2. Does perturbing DDIT3 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":461 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1959 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":636 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1098 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":550 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":737 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2373 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":162 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1122 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000142669. Does perturbing AARS lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of SH3BGRL3. Does perturbing AARS lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":11 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2400 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1437 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2375 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000197989. Does perturbing OST4 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of SNHG12. Does perturbing OST4 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1361 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1202 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1967 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1798 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000070785 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070785 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and EIF2B3 expression is observed. Does this perturbation lead to a significant difference in EIF2B3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":663 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":982 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":765 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2157 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":777 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1702 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2503 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2397 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":670 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2363 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000158869. Does perturbing IARS2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of FCER1G. Does perturbing IARS2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1071 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2108 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1787 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2393 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000116761 is measured. Determine whether ENSG00000116761 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of CTH is measured. Determine whether CTH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":376 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1583 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2439 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2088 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":946 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2542 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":976 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1613 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":406 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2203 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1672 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000177954. Does perturbing DDIT3 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of RPS27. Does perturbing DDIT3 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":471 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2062 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":60 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1603 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":694 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ENSG00000244038 expression is quantified. Does this perturbation result in a significant change in ENSG00000244038 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and DDOST expression is quantified. Does this perturbation result in a significant change in DDOST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":482 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1799 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000016490. Does perturbing IER3IP1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of CLCA1. Does perturbing IER3IP1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1111 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2230 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":764 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":314 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":582 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":229 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1812 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":173 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1059 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000188672. Does perturbing DDOST lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of RHCE. Does perturbing DDOST lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":491 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2465 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000117318 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117318 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":308 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1277 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":763 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2429 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000198771 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1317 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1675 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1206 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000198756. Does perturbing EIF2S1 lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of COLGALT2. Does perturbing EIF2S1 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":731 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000092621. Does perturbing TIMM23 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of PHGDH. Does perturbing TIMM23 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2231 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000159388. Does perturbing COPZ1 lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of BTG2. Does perturbing COPZ1 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":341 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2460 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000159352 is measured. Does this perturbation cause a significant change in ENSG00000159352 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of PSMD4 is measured. Does this perturbation cause a significant change in PSMD4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1470 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":315 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":495 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1417 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1279 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":488 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000169442. Does perturbing UFL1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of CD52. Does perturbing UFL1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2451 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1483 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1335 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000177954. Does perturbing GMPPB lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of RPS27. Does perturbing GMPPB lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":841 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2540 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2326 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1190 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1987 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1679 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2325 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000116761. Does perturbing CREB1 lead to a significant change in ENSG00000116761 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of CTH. Does perturbing CREB1 lead to a significant change in CTH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":371 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1783 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":18 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1055 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2569 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000117289. Does perturbing SEC61A1 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of TXNIP. Does perturbing SEC61A1 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1671 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1080 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2304 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000158869. Does perturbing P4HB lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of FCER1G. Does perturbing P4HB lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1391 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1736 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":797 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2036 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":266 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":250 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2437 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1487 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000235169 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in SMIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1295 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000135838 is measured. Does this perturbation cause a significant change in ENSG00000135838 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of NPL is measured. Does this perturbation cause a significant change in NPL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":270 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2396 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000169442. Does perturbing SEC63 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of CD52. Does perturbing SEC63 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1741 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2352 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1657 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1573 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1793 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1042 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":100 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1873 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":29 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":63 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":877 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":224 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000198492. Does perturbing SRPRB lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of YTHDF2. Does perturbing SRPRB lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2091 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2080 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1114 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000227533 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000227533 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":208 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of ENSG00000143333. Does perturbing DDIT3 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDIT3 and examine the expression of RGS16. Does perturbing DDIT3 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":451 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2302 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":926 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1039 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1795 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":526 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000198492. Does perturbing PDIA6 lead to a significant change in ENSG00000198492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of YTHDF2. Does perturbing PDIA6 lead to a significant change in YTHDF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1431 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2416 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000143226. Does perturbing AARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of FCGR2A. Does perturbing AARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":21 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000244038 is measured. Does this perturbation cause a significant change in ENSG00000244038 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of DDOST is measured. Does this perturbation cause a significant change in DDOST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":480 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2143 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2305 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1804 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2077 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1637 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1917 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":838 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000169442. Does perturbing SLC39A7 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of CD52. Does perturbing SLC39A7 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1841 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":884 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2223 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000162511 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor LAPTM5 expression. Decide whether this perturbation leads to a significant alteration in LAPTM5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1668 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1469 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1924 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":726 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000188672. Does perturbing GMPPB lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of RHCE. Does perturbing GMPPB lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":861 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":437 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":262 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":817 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP72, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2027 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000198771 expression is measured. Determine whether ENSG00000198771 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":299 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1720 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1807 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2008 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2249 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1740 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2286 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1079 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1724 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ENSG00000127125. Does perturbing TTI2 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of PPCS. Does perturbing TTI2 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2411 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":939 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1716 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1608 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":742 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":934 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":415 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of ENSG00000158869. Does perturbing STT3A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STT3A and examine the expression of FCER1G. Does perturbing STT3A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2121 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2089 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":433 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000163191 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in S100A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1555 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2207 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1708 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2413 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":987 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":899 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":528 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1418 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":956 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2087 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000016490. Does perturbing DDRGK1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of CLCA1. Does perturbing DDRGK1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":531 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1030 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1854 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1540 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000117318 is measured. Does this perturbation cause a significant change in ENSG00000117318 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":300 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":623 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":828 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":388 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000158869. Does perturbing HSPA5 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of FCER1G. Does perturbing HSPA5 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":961 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000197989. Does perturbing FECH lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of SNHG12. Does perturbing FECH lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":791 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ENSG00000188672. Does perturbing TTI2 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of RHCE. Does perturbing TTI2 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2401 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000159352 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159352 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and PSMD4 expression is observed. Does this perturbation lead to a significant difference in PSMD4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1473 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":129 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":244 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":152 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000177954. Does perturbing MRGBP lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of RPS27. Does perturbing MRGBP lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1241 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000162511. Does perturbing ASCC3 lead to a significant change in ENSG00000162511 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of LAPTM5. Does perturbing ASCC3 lead to a significant change in LAPTM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":111 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1085 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":873 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":867 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1562 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":96 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1632 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":166 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1519 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":707 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1806 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":38 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":868 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":862 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":463 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":5 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2344 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000070785 is measured. Determine whether ENSG00000070785 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of EIF2B3 is measured. Determine whether EIF2B3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":666 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1373 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":237 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":880 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000197989. Does perturbing UFM1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of SNHG12. Does perturbing UFM1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2471 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2204 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1862 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":693 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1179 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000169442. Does perturbing SCYL1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of CD52. Does perturbing SCYL1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1621 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1794 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":805 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2486 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2179 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":146 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000162664. Does this perturbation cause a significant change in ENSG00000162664 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ZNF326. Does this perturbation cause a significant change in ZNF326 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2554 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1585 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":676 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":562 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FARSB, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":767 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":819 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":527 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1138 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":84 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1012 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":464 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER3IP1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1124 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1935 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":44 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":787 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000092621. Does perturbing SLMO2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of PHGDH. Does perturbing SLMO2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1861 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":857 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000158869. Does perturbing SLC35B1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of FCER1G. Does perturbing SLC35B1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1811 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":516 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":746 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2195 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":159 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":565 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2199 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":703 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2320 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1344 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1813 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1338 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1735 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":925 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":549 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2539 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":424 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1488 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2066 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":212 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1764 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2335 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000188672. Does perturbing SYVN1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of RHCE. Does perturbing SYVN1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2151 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1070 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1686 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2467 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":583 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":62 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000188290 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188290 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor HES4 expression. Decide whether this perturbation leads to a significant alteration in HES4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1238 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1093 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2029 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2208 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1690 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":147 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":835 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":438 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2216 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":943 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1306 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1903 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1155 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":367 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":444 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1018 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000235169. Does perturbing MTHFD1 lead to a significant change in ENSG00000235169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of SMIM1. Does perturbing MTHFD1 lead to a significant change in SMIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1291 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":802 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2334 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDRGK1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":536 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2007 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1753 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1755 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1077 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2035 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1250 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1988 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2300 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":570 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1695 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":654 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1576 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1648 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1894 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2405 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1734 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2140 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2366 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2482 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2287 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000135842 is measured. Determine whether ENSG00000135842 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of FAM129A is measured. Determine whether FAM129A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1216 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2118 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1704 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1088 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2355 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MANF, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1187 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":616 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2096 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2050 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2197 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2275 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":574 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":886 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2330 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1037 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":748 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ASCC3 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":92 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":929 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1367 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1464 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARHGAP22 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":83 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1365 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":462 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":612 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":653 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":496 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":872 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":560 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000158869. Does perturbing SRPR lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of FCER1G. Does perturbing SRPR lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2061 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1429 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1253 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":995 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000188672. Does perturbing MTHFD1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RHCE. Does perturbing MTHFD1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1301 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000135837 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135837 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and CEP350 expression is observed. Does this perturbation lead to a significant difference in CEP350 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2513 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":235 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2009 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000135838. Does this perturbation cause a significant change in ENSG00000135838 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of NPL. Does this perturbation cause a significant change in NPL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":274 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2442 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000092621. Does perturbing SARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of PHGDH. Does perturbing SARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1601 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000117289. Does perturbing IDH3A lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of TXNIP. Does perturbing IDH3A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1081 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000188672. Does perturbing OST4 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of RHCE. Does perturbing OST4 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1351 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1839 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1505 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PDIA6, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1427 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2445 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1808 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1444 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2172 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1447 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000227533 expression is measured. Determine whether ENSG00000227533 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":209 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2548 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000162664 expression is measured. Determine whether ENSG00000162664 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ZNF326 expression is measured. Determine whether ZNF326 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2559 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000159352 expression is quantified. Does this perturbation result in a significant change in ENSG00000159352 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and PSMD4 expression is quantified. Does this perturbation result in a significant change in PSMD4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1472 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1774 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2237 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2177 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":310 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":588 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000198771. Does this perturbation cause a significant change in ENSG00000198771 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":294 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2444 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":398 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2427 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1330 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1904 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1825 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TELO2, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2217 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1150 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":319 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000188672. Does perturbing CCND3 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of RHCE. Does perturbing CCND3 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":261 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2380 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":569 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1606 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1405 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":973 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2133 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1694 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1056 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2464 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1757 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":507 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1848 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1503 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":620 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":512 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":845 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000169442. Does perturbing SPCS2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of CD52. Does perturbing SPCS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1921 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1132 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":949 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1307 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":132 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":964 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":33 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2430 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1287 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1096 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1822 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":858 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000198771. Does this perturbation cause a significant change in ENSG00000198771 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1314 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":844 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":179 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2182 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000143226. Does perturbing HARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of FCGR2A. Does perturbing HARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":921 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":359 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1200 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2502 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000177954. Does perturbing GNPNAT1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of RPS27. Does perturbing GNPNAT1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":891 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1957 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000163386 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in NBPF10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2495 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1252 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2544 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":417 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2099 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1737 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1347 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":393 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":904 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1420 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and ENSG00000163386 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163386 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which XRN1 is perturbed and NBPF10 expression is observed. Does this perturbation lead to a significant difference in NBPF10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2493 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":362 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1847 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":580 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000158869. Does perturbing SEC61A1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of FCER1G. Does perturbing SEC61A1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1651 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1960 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":932 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1890 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2188 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":633 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":330 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2040 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1082 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000016490. Does perturbing HYOU1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of CLCA1. Does perturbing HYOU1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1021 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":622 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000159352 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159352 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor PSMD4 expression. Decide whether this perturbation leads to a significant alteration in PSMD4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1478 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2428 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1275 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of ENSG00000227533 is measured. Does this perturbation cause a significant change in ENSG00000227533 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":200 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1898 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and ENSG00000188290 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188290 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRGBP is perturbed and HES4 expression is observed. Does this perturbation lead to a significant difference in HES4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1233 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1617 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1140 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000188290 expression is quantified. Does this perturbation result in a significant change in ENSG00000188290 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and HES4 expression is quantified. Does this perturbation result in a significant change in HES4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1232 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000142669. Does perturbing COPZ1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of SH3BGRL3. Does perturbing COPZ1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":351 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":743 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":856 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1083 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1785 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":138 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":389 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000135842 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in FAM129A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1215 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":958 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":850 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":954 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GNPNAT1 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":870 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OST4 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1363 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000135838 is measured. Determine whether ENSG00000135838 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of NPL is measured. Determine whether NPL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":276 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2145 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000016490. Does perturbing DARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of CLCA1. Does perturbing DARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":421 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":637 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1845 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":820 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1245 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000158869. Does perturbing SLMO2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FCER1G. Does perturbing SLMO2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1881 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1387 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":56 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1605 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2052 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2039 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2115 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000158869. Does perturbing UFM1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of FCER1G. Does perturbing UFM1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2461 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":587 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STT3A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2122 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1719 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1249 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC63 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1760 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1175 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1885 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2407 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMEM167A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2356 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":513 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":568 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":334 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTDSS1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1516 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1789 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1548 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2084 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1396 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000169442. Does perturbing PDIA6 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of CD52. Does perturbing PDIA6 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1421 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":9 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":506 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2472 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":90 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2236 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1827 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":3 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2125 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1778 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":898 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000198771 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198771 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1313 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2187 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2488 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2205 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SOCS1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1897 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":624 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1274 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":566 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":698 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATP5B is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":136 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2306 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2190 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":529 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":795 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1370 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1453 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPR is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2060 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":418 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PDIA6 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1410 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1833 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLMO2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1875 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000197989. Does perturbing SRP68 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of SNHG12. Does perturbing SRP68 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2001 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2020 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of ENSG00000169442. Does perturbing SYVN1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SYVN1 and examine the expression of CD52. Does perturbing SYVN1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2131 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1276 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":656 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000116761 is measured. Does this perturbation cause a significant change in ENSG00000116761 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of CTH is measured. Does this perturbation cause a significant change in CTH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":370 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEL1L and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1784 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in ENSG00000135837 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of XRN1 is associated with a significant change in CEP350 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2515 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":710 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2175 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":837 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":177 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":888 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1963 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2295 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":240 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1642 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":313 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1536 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":466 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2348 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":128 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000169442. Does perturbing DERL2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of CD52. Does perturbing DERL2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":541 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1507 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":66 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2378 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1588 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1993 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1457 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1110 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPRB and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2074 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1336 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2067 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1446 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000177954. Does perturbing SEL1L lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of RPS27. Does perturbing SEL1L lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1781 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1054 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":58 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":849 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":176 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":283 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1580 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1860 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000116761 expression is quantified. Does this perturbation result in a significant change in ENSG00000116761 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and CTH expression is quantified. Does this perturbation result in a significant change in CTH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2572 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARHGAP22 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":74 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1870 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":773 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMM50 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1586 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2456 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":613 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":20 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":457 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPRB is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2079 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":105 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of ENSG00000244038 is measured. Does this perturbation cause a significant change in ENSG00000244038 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DHDDS is perturbed and the expression of DDOST is measured. Does this perturbation cause a significant change in DDOST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":590 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PPWD1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1454 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":732 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":239 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":344 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000188290 is measured. Does this perturbation cause a significant change in ENSG00000188290 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of HES4 is measured. Does this perturbation cause a significant change in HES4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1230 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":93 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2564 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2164 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1022 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2485 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000197989. Does perturbing MANF lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of SNHG12. Does perturbing MANF lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1171 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1224 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000158869. Does perturbing SEC63 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of FCER1G. Does perturbing SEC63 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1751 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":643 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1146 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000177954. Does perturbing SPCS2 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of RPS27. Does perturbing SPCS2 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1941 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2313 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1248 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1333 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000143226. Does perturbing EIF2B2 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of FCGR2A. Does perturbing EIF2B2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":651 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2116 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":133 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2426 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":345 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1173 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2169 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":103 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":317 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1627 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":489 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1538 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000163386. Does this perturbation cause a significant change in ENSG00000163386 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of NBPF10. Does this perturbation cause a significant change in NBPF10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2494 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2290 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":337 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000235169 expression is quantified. Does this perturbation result in a significant change in ENSG00000235169 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and SMIM1 expression is quantified. Does this perturbation result in a significant change in SMIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1292 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":933 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":784 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2257 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and ENSG00000235169 expression is observed. Does this perturbation lead to a significant difference in ENSG00000235169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MTHFD1 is perturbed and SMIM1 expression is observed. Does this perturbation lead to a significant difference in SMIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1293 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2049 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000197989. Does perturbing IDH3A lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of SNHG12. Does perturbing IDH3A lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1101 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1796 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000135838 expression is quantified. Does this perturbation result in a significant change in ENSG00000135838 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and NPL expression is quantified. Does this perturbation result in a significant change in NPL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":272 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":499 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":14 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSD17B12 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":959 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1965 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1919 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":89 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":728 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000092621. Does perturbing DNAJC19 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of PHGDH. Does perturbing DNAJC19 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":611 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":422 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":453 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SYVN1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2135 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GBF1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":829 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":312 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":855 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2536 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2265 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2399 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":79 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1357 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":120 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000163386 is measured. Does this perturbation cause a significant change in ENSG00000163386 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of NBPF10 is measured. Does this perturbation cause a significant change in NBPF10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2490 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":360 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1530 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2138 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":189 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000163386 expression is measured. Determine whether ENSG00000163386 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and NBPF10 expression is measured. Determine whether NBPF10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2499 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1144 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":617 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of ENSG00000169442. Does perturbing SLC35B1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC35B1 and examine the expression of CD52. Does perturbing SLC35B1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1801 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":940 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":860 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1578 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000244038 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in DDOST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":595 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1950 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2028 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1758 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000197989. Does perturbing SEL1L lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of SNHG12. Does perturbing SEL1L lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1791 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1625 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000227533. Does perturbing CAD lead to a significant change in ENSG00000227533 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of SLC2A1-AS1. Does perturbing CAD lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":201 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000143333. Does perturbing CREB1 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of RGS16. Does perturbing CREB1 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":361 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":109 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1272 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2045 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMEM167A and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2364 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000162511 expression is quantified. Does this perturbation result in a significant change in ENSG00000162511 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and LAPTM5 expression is quantified. Does this perturbation result in a significant change in LAPTM5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1662 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":769 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2247 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000198771 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198771 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1318 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1456 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000092621. Does perturbing EIF2S1 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of PHGDH. Does perturbing EIF2S1 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":721 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in ENSG00000031698 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SARS is associated with a significant change in SARS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1595 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":989 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1485 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000235169 expression is quantified. Does this perturbation result in a significant change in ENSG00000235169 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and SMIM1 expression is quantified. Does this perturbation result in a significant change in SMIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1492 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":247 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2350 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":369 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":219 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":754 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000162664 is measured. Does this perturbation cause a significant change in ENSG00000162664 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ZNF326 is measured. Does this perturbation cause a significant change in ZNF326 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2550 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":508 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000117318 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":305 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":282 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":358 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000142669. Does perturbing IER3IP1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of SH3BGRL3. Does perturbing IER3IP1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1131 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1863 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of ENSG00000143226. Does perturbing SLMO2 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLMO2 and examine the expression of FCGR2A. Does perturbing SLMO2 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1871 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":685 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1027 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1867 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000163191 expression is measured. Determine whether ENSG00000163191 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and S100A11 expression is measured. Determine whether S100A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1559 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2415 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":766 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1064 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2212 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000092621. Does perturbing TIMM44 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of PHGDH. Does perturbing TIMM44 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2251 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1762 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2148 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1189 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2370 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1428 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":228 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMM50 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1563 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000244038 expression is observed. Does this perturbation lead to a significant difference in ENSG00000244038 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and DDOST expression is observed. Does this perturbation lead to a significant difference in DDOST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":593 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1823 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000198756 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1067 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CAD is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":199 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000169442. Does perturbing TELO2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CD52. Does perturbing TELO2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2191 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1869 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000092621. Does perturbing SAMM50 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of PHGDH. Does perturbing SAMM50 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1561 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":690 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":399 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC35B1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1816 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":604 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000159352 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in PSMD4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1475 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":340 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1227 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, YIPF5 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2530 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000162511 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of LAPTM5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1667 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATP5B is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":142 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1304 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000244038 expression is quantified. Does this perturbation result in a significant change in ENSG00000244038 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and DDOST expression is quantified. Does this perturbation result in a significant change in DDOST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":972 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and ENSG00000162511 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162511 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ASCC3 is perturbed and LAPTM5 expression is observed. Does this perturbation lead to a significant difference in LAPTM5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":113 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":913 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1710 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":647 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEL1L is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1773 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1384 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor ENSG00000198492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PDIA6 and monitor YTHDF2 expression. Decide whether this perturbation leads to a significant alteration in YTHDF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1438 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000198492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and YTHDF2 expression is observed. Does this perturbation lead to a significant difference in YTHDF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1433 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SOCS1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1914 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DHDDS, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":597 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":680 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1518 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRPR is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2069 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":916 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2292 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1528 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ASCC3 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":106 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2174 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000117289. Does perturbing CCND3 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of TXNIP. Does perturbing CCND3 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":251 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":268 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2470 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1125 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2545 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DERL2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":540 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":470 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP72 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2018 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA5 is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":979 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1329 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI2, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2417 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2317 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":352 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1325 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":502 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000135842. Does perturbing MARS lead to a significant change in ENSG00000135842 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of FAM129A. Does perturbing MARS lead to a significant change in FAM129A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1211 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":216 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000135837 is measured. Determine whether ENSG00000135837 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of CEP350 is measured. Determine whether CEP350 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2516 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1923 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":760 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1643 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1409 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":779 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1639 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":10 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2288 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":576 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000117289. Does perturbing YIPF5 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of TXNIP. Does perturbing YIPF5 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2541 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000142669. Does perturbing TMED2 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of SH3BGRL3. Does perturbing TMED2 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2331 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2385 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1094 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2473 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1455 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000092621. Does perturbing TARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of PHGDH. Does perturbing TARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2161 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DAD1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":396 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2058 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000127125. Does perturbing SRPR lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of PPCS. Does perturbing SRPR lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2051 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1533 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1570 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":702 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1884 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2383 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1728 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2269 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":245 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1229 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of ENSG00000169442. Does perturbing ARHGAP22 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of CD52. Does perturbing ARHGAP22 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":71 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1614 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1699 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AARS is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":19 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000135838 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135838 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and NPL expression is observed. Does this perturbation lead to a significant difference in NPL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":273 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2222 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1896 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1777 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1395 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":76 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of ENSG00000158869. Does perturbing IDH3A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IDH3A and examine the expression of FCER1G. Does perturbing IDH3A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1091 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2316 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000169442. Does perturbing ASCC3 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of CD52. Does perturbing ASCC3 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":91 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":59 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2468 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":356 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000162664 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ZNF326 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2555 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":999 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1442 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61A1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1658 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":222 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1407 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":328 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000016490. Does perturbing DNAJC19 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of CLCA1. Does perturbing DNAJC19 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":601 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000198771 expression is quantified. Does this perturbation result in a significant change in ENSG00000198771 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1312 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":130 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":184 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":854 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1380 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1673 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1350 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1392 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2043 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":198 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000143333. Does perturbing BHLHE40 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of RGS16. Does perturbing BHLHE40 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":161 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GNPNAT1 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":879 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CCND3 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":258 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":243 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":364 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000244038. Does perturbing HSPA5 lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of DDOST. Does perturbing HSPA5 lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":971 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":108 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2218 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1128 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC35B1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1805 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDIT3 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":473 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1480 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1060 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2447 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000116761 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in CTH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2575 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":195 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":193 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2398 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1887 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000163191. Does perturbing QARS lead to a significant change in ENSG00000163191 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of S100A11. Does perturbing QARS lead to a significant change in S100A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1551 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2377 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of ENSG00000092621. Does perturbing IARS2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IARS2 and examine the expression of PHGDH. Does perturbing IARS2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1051 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":363 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CARS is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":232 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2529 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000244038. Does perturbing DHDDS lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of DDOST. Does perturbing DHDDS lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":591 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000117289. Does perturbing GNPNAT1 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of TXNIP. Does perturbing GNPNAT1 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":871 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2367 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2297 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000016490. Does perturbing HARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of CLCA1. Does perturbing HARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":911 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":143 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1909 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC35B1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1817 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1999 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1052 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2546 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2566 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRP68, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1997 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000116761 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in CTH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":375 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":923 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1600 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000198771 is measured. Determine whether ENSG00000198771 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":296 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPRB and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2078 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":905 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":735 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000188672. Does perturbing CAD lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of RHCE. Does perturbing CAD lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":191 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000130766 is measured. Determine whether ENSG00000130766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of SESN2 is measured. Determine whether SESN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":386 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":836 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFM1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2462 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1543 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and ENSG00000031698 expression is quantified. Does this perturbation result in a significant change in ENSG00000031698 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and SARS expression is quantified. Does this perturbation result in a significant change in SARS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1592 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1289 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1687 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1434 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of ENSG00000127125. Does perturbing GNPNAT1 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GNPNAT1 and examine the expression of PPCS. Does perturbing GNPNAT1 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":881 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SOCS1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1899 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1958 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1002 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000197989. Does perturbing KCTD16 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of SNHG12. Does perturbing KCTD16 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1151 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":355 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1072 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":474 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2408 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":67 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1656 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDOST, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":487 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEL1L is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1779 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":906 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1927 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":915 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":598 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1113 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1209 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DARS, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":447 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":225 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1836 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":798 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1650 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":874 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":834 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRPL39, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1267 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IDH3A and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1108 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1929 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MANF is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1170 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1106 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TELO2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2198 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000177954. Does perturbing DAD1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of RPS27. Does perturbing DAD1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":411 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000016490. Does perturbing CHERP lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of CLCA1. Does perturbing CHERP lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":281 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1966 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000198756 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1065 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B4 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":700 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2289 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of ENSG00000016490. Does perturbing SEC61B lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of CLCA1. Does perturbing SEC61B lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1691 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000198771 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":295 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":683 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000016490. Does perturbing TARS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of CLCA1. Does perturbing TARS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2171 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2368 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and ENSG00000116761 expression is measured. Determine whether ENSG00000116761 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CREB1 is perturbed and CTH expression is measured. Determine whether CTH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":379 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000130766 expression is measured. Determine whether ENSG00000130766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and SESN2 expression is measured. Determine whether SESN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":469 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000158869. Does perturbing SOCS1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of FCER1G. Does perturbing SOCS1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1911 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":163 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000197989. Does perturbing SRPRB lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of SNHG12. Does perturbing SRPRB lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2081 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":233 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000135838. Does perturbing CHERP lead to a significant change in ENSG00000135838 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of NPL. Does perturbing CHERP lead to a significant change in NPL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":271 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2070 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":384 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2178 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1874 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMM50 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1568 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000135837 is measured. Does this perturbation cause a significant change in ENSG00000135837 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of CEP350 is measured. Does this perturbation cause a significant change in CEP350 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2510 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1092 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":192 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000177954. Does perturbing HYOU1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of RPS27. Does perturbing HYOU1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1041 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1786 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1990 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000130766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in SESN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":175 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000135837 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135837 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor CEP350 expression. Decide whether this perturbation leads to a significant alteration in CEP350 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2518 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2432 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2010 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1649 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2176 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC35B1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1802 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TELO2 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2215 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1889 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2476 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1376 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1116 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":440 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000143226. Does perturbing NEDD8 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of FCGR2A. Does perturbing NEDD8 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1321 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000235169. Does perturbing PSMD4 lead to a significant change in ENSG00000235169 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of SMIM1. Does perturbing PSMD4 lead to a significant change in SMIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1491 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2073 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP72 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2030 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1087 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000117318. Does perturbing COPB1 lead to a significant change in ENSG00000117318 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ID3. Does perturbing COPB1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":301 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1273 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1159 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":833 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2165 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FECH is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":785 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1368 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARHGAP22 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":69 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":714 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2002 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of ENSG00000127125 is measured. Does this perturbation cause a significant change in ENSG00000127125 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI2 is perturbed and the expression of PPCS is measured. Does this perturbation cause a significant change in PPCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2410 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1539 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPZ1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":350 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1424 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1048 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1154 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1394 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1016 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":823 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1153 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":739 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1034 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DERL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":555 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000169442. Does perturbing COPB1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of CD52. Does perturbing COPB1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":311 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1400 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1644 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of ENSG00000116761. Does this perturbation cause a significant change in ENSG00000116761 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CREB1 and then measure expression of CTH. Does this perturbation cause a significant change in CTH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":374 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1422 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1766 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":220 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000198771 is measured. Does this perturbation cause a significant change in ENSG00000198771 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1310 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HSPA9 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1009 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":649 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1534 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2412 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61A1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1652 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFL1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2455 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2100 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1095 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1168 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2303 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61B and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1684 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TARS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2185 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRGBP is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1240 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMM50, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1577 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2152 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":448 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1332 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1900 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of ENSG00000016490. Does perturbing XRN1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of CLCA1. Does perturbing XRN1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2501 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":80 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SYVN1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2153 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2012 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPRB is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2083 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":333 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":806 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OST4 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1360 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1916 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000163386 is measured. Determine whether ENSG00000163386 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of NBPF10 is measured. Determine whether NBPF10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2496 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2386 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2159 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2238 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":95 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000142669. Does perturbing DARS lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of SH3BGRL3. Does perturbing DARS lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":441 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000031698 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of SARS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1597 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1878 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":57 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000158869. Does perturbing SRP68 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of FCER1G. Does perturbing SRP68 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1981 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2409 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of ENSG00000162511. Does perturbing SEC61A1 lead to a significant change in ENSG00000162511 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61A1 and examine the expression of LAPTM5. Does perturbing SEC61A1 lead to a significant change in LAPTM5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1661 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000031698 is measured. Does this perturbation cause a significant change in ENSG00000031698 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of SARS is measured. Does this perturbation cause a significant change in SARS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1590 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000163386 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of NBPF10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2497 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":503 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000235169 expression is measured. Determine whether ENSG00000235169 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and SMIM1 expression is measured. Determine whether SMIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1299 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2345 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of ENSG00000227533 is measured. Determine whether ENSG00000227533 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":206 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":546 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMM50 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1560 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000244038 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of DDOST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":977 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER3IP1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1135 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1205 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":810 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2463 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":720 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1953 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":740 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1463 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1035 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TTI2 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2403 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":677 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":639 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1744 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000070785 expression is quantified. Does this perturbation result in a significant change in ENSG00000070785 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and EIF2B3 expression is quantified. Does this perturbation result in a significant change in EIF2B3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":662 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":657 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDIT3 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":454 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1976 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":37 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1222 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000092621. Does perturbing EIF2B2 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of PHGDH. Does perturbing EIF2B2 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":631 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MARS, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1207 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2163 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2328 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of ENSG00000092621. Does perturbing HARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HARS and examine the expression of PHGDH. Does perturbing HARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":901 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":223 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1176 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1157 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1270 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000143226. Does perturbing CARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of FCGR2A. Does perturbing CARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":221 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1259 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":127 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000158869. Does perturbing SPCS3 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of FCER1G. Does perturbing SPCS3 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1961 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2353 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA9 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":990 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2123 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000188672. Does perturbing SOCS1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RHCE. Does perturbing SOCS1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1901 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":554 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":6 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC63 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1756 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000016490. Does perturbing PPWD1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CLCA1. Does perturbing PPWD1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1451 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":197 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":579 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMED10, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2307 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1772 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDOST is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":509 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000235169 expression is measured. Determine whether ENSG00000235169 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and SMIM1 expression is measured. Determine whether SMIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1499 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000116761 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116761 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor CTH expression. Decide whether this perturbation leads to a significant alteration in CTH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2578 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":68 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, QARS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1549 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":935 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1025 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLMO2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1880 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2034 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1619 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":608 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1416 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":646 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2273 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1408 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1835 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2117 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":510 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000135838 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of NPL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":277 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61A1, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1677 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":145 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000197989. Does perturbing DDRGK1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of SNHG12. Does perturbing DDRGK1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":511 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":659 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000227533 expression is observed. Does this perturbation lead to a significant difference in ENSG00000227533 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":203 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":772 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":966 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2170 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPB1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":318 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMEM167A is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2365 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":429 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI2 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2419 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":434 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1194 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AARS is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":15 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2404 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000158869. Does perturbing QARS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of FCER1G. Does perturbing QARS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1541 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLMO2 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1879 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":368 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2068 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1980 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000162511 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in LAPTM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1665 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1830 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1149 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000142669. Does perturbing HSD17B12 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of SH3BGRL3. Does perturbing HSD17B12 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":941 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2092 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STT3A is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2105 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MARS is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1226 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":12 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1192 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of ENSG00000117289. Does perturbing SEL1L lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEL1L and examine the expression of TXNIP. Does perturbing SEL1L lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1771 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS3 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1955 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1393 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000143226. Does perturbing FARSB lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of FCGR2A. Does perturbing FARSB lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":771 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDRGK1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":533 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000016490. Does perturbing GBF1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of CLCA1. Does perturbing GBF1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":831 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":154 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2537 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1936 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2252 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1188 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000016490. Does perturbing TELO2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of CLCA1. Does perturbing TELO2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2201 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GMPPB and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":864 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":419 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1682 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OST4, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1377 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of ENSG00000016490. Does perturbing CCND3 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CCND3 and examine the expression of CLCA1. Does perturbing CCND3 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":241 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SCYL1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1629 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2023 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1616 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":160 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ENSG00000117318. Does this perturbation cause a significant change in ENSG00000117318 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":304 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":22 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2263 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1517 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000235169 is measured. Determine whether ENSG00000235169 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of SMIM1 is measured. Determine whether SMIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1496 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1068 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000092621. Does perturbing ATP5B lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of PHGDH. Does perturbing ATP5B lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":121 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA9 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":992 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MTHFD1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1302 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":4 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":404 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2S1 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":730 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":572 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPR is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2056 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":930 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":460 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":0 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1423 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GBF1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":818 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2443 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2154 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARHGAP22 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":78 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor ENSG00000163191 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163191 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb QARS and monitor S100A11 expression. Decide whether this perturbation leads to a significant alteration in S100A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1558 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000135838 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135838 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor NPL expression. Decide whether this perturbation leads to a significant alteration in NPL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":278 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":799 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":997 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":426 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1857 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEL1L is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1775 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":896 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1255 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000198756 is measured. Does this perturbation cause a significant change in ENSG00000198756 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":230 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DNAJC19 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":619 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":458 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":567 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of ENSG00000197989. Does perturbing HYOU1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HYOU1 and examine the expression of SNHG12. Does perturbing HYOU1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1031 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1630 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS3 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1970 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SYVN1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2158 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":459 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":770 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000158869. Does perturbing AMIGO3 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of FCER1G. Does perturbing AMIGO3 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":41 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000235169 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of SMIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1497 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1782 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1732 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI2 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2418 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":716 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRPR and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2048 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":215 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1713 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":353 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B3 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":673 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1107 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000198771 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":297 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1575 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1722 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1278 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and ENSG00000198771 expression is quantified. Does this perturbation result in a significant change in ENSG00000198771 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CHERP is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":292 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AMIGO3, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":47 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":135 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000162511 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162511 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and LAPTM5 expression is observed. Does this perturbation lead to a significant difference in LAPTM5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1663 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1729 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2440 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1634 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2193 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1767 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":190 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1546 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000188672. Does perturbing PTDSS1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of RHCE. Does perturbing PTDSS1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1511 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1426 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000162664 is measured. Determine whether ENSG00000162664 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF326 is perturbed and the expression of ZNF326 is measured. Determine whether ZNF326 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2556 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2147 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP72 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2019 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC35B1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1828 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":822 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":43 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000016490. Does perturbing SAMM50 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of CLCA1. Does perturbing SAMM50 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1571 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of ENSG00000064886. Does perturbing BHLHE40 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BHLHE40 and examine the expression of CHI3L2. Does perturbing BHLHE40 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":151 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DHDDS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":578 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1165 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2234 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DNAJC19, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":607 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CHERP is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":280 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2469 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000162511. Does this perturbation cause a significant change in ENSG00000162511 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of LAPTM5. Does this perturbation cause a significant change in LAPTM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":114 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1185 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2318 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GNPNAT1 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":876 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2136 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2322 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2219 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IDH3A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1097 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000031698. Does this perturbation cause a significant change in ENSG00000031698 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of SARS. Does this perturbation cause a significant change in SARS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1594 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":922 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATP5B, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":137 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1284 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC63 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1754 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, P4HB is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1390 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2395 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000198492 expression is quantified. Does this perturbation result in a significant change in ENSG00000198492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and YTHDF2 expression is quantified. Does this perturbation result in a significant change in YTHDF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1432 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPZ1 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":343 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":900 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000135838 expression is measured. Determine whether ENSG00000135838 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and NPL expression is measured. Determine whether NPL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":279 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":548 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BHLHE40 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":153 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of ENSG00000117289. Does perturbing CAD lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CAD and examine the expression of TXNIP. Does perturbing CAD lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":181 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2226 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1379 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of ENSG00000235169. Does this perturbation cause a significant change in ENSG00000235169 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MTHFD1 and then measure expression of SMIM1. Does this perturbation cause a significant change in SMIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1294 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1535 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IARS2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1050 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1322 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":920 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":869 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1886 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of ENSG00000031698 is measured. Determine whether ENSG00000031698 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SARS is perturbed and the expression of SARS is measured. Determine whether SARS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1596 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2146 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000163386 expression is quantified. Does this perturbation result in a significant change in ENSG00000163386 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and NBPF10 expression is quantified. Does this perturbation result in a significant change in NBPF10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2492 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1738 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of ENSG00000163191 is measured. Does this perturbation cause a significant change in ENSG00000163191 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, QARS is perturbed and the expression of S100A11 is measured. Does this perturbation cause a significant change in S100A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1550 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2459 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1512 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":85 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2369 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000169442. Does perturbing MRGBP lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of CD52. Does perturbing MRGBP lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1251 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":336 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000117289. Does perturbing KCTD16 lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of TXNIP. Does perturbing KCTD16 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1161 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1525 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OST4 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1364 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2025 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":26 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1819 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of ENSG00000127125. Does perturbing OST4 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OST4 and examine the expression of PPCS. Does perturbing OST4 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1371 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000188672 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of RHCE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":267 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARHGAP22 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":86 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":329 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DAD1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":409 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1768 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of ENSG00000142669. Does perturbing HSPA5 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA5 and examine the expression of SH3BGRL3. Does perturbing HSPA5 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":981 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000016490. Does perturbing TMED2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of CLCA1. Does perturbing TMED2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2321 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFM1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2480 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":534 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1130 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC63, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1747 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KCTD16 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1169 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SYVN1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2139 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and ENSG00000135842 expression is quantified. Does this perturbation result in a significant change in ENSG00000135842 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MARS is perturbed and FAM129A expression is quantified. Does this perturbation result in a significant change in FAM129A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1212 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2532 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000235169 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000235169 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor SMIM1 expression. Decide whether this perturbation leads to a significant alteration in SMIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1298 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000163386 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163386 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor NBPF10 expression. Decide whether this perturbation leads to a significant alteration in NBPF10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2498 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2228 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1247 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":918 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":124 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":655 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1922 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1790 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2242 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UFL1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2452 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ENSG00000143333. Does perturbing ZNF326 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of RGS16. Does perturbing ZNF326 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2561 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FARSB is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":762 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of ENSG00000016490. Does perturbing EIF2B2 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B2 and examine the expression of CLCA1. Does perturbing EIF2B2 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":641 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":413 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000188290. Does this perturbation cause a significant change in ENSG00000188290 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of HES4. Does this perturbation cause a significant change in HES4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1234 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":692 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and ENSG00000031698 expression is observed. Does this perturbation lead to a significant difference in ENSG00000031698 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SARS is perturbed and SARS expression is observed. Does this perturbation lead to a significant difference in SARS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1593 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":783 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS3 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1969 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":322 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GMPPB is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":840 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B3 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":686 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1984 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1004 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2433 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":974 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2260 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BHLHE40 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":165 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000169442. Does perturbing PTDSS1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of CD52. Does perturbing PTDSS1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1521 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED10 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2282 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":87 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1182 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1265 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEL1L, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1797 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1448 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CHERP, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":287 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of ENSG00000198492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPRB, does the expression profile of YTHDF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2097 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER3IP1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1126 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":699 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":708 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000016490. Does perturbing TTI1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of CLCA1. Does perturbing TTI1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2391 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1260 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1148 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DNAJC19 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":602 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PPWD1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1449 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61A1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1653 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2114 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1220 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SYVN1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2156 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000162511 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of LAPTM5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":117 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of ENSG00000142669. Does perturbing DNAJC19 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DNAJC19 and examine the expression of SH3BGRL3. Does perturbing DNAJC19 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":621 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1043 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2402 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED10 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2299 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1604 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2484 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of ENSG00000158869. Does perturbing FECH lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FECH and examine the expression of FCER1G. Does perturbing FECH lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":801 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":733 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":402 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000162511 expression is measured. Determine whether ENSG00000162511 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and LAPTM5 expression is measured. Determine whether LAPTM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1669 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":432 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1486 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KCTD16, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1147 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1858 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":812 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":744 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":866 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1947 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of ENSG00000142669. Does perturbing SPCS2 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS2 and examine the expression of SH3BGRL3. Does perturbing SPCS2 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1931 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TTI1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2388 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DAD1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":408 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1602 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1569 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CHERP is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":289 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1359 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":644 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":955 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of ENSG00000169442. Does perturbing COPZ1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPZ1 and examine the expression of CD52. Does perturbing COPZ1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":331 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1406 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1058 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":218 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61G and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1714 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":684 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":928 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PPWD1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1443 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1015 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":892 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATP5B and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":148 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MANF is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1195 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM23, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2227 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2562 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM44 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2255 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSD17B12 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":945 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":563 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2374 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1968 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTDSS1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1527 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of ENSG00000198492 is measured. Does this perturbation cause a significant change in ENSG00000198492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRPRB is perturbed and the expression of YTHDF2 is measured. Does this perturbation cause a significant change in YTHDF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2090 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DAD1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":403 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1709 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, YIPF5 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2549 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":788 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PPWD1, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1467 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and ENSG00000031698 expression is measured. Determine whether ENSG00000031698 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SARS is perturbed and SARS expression is measured. Determine whether SARS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1599 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of ENSG00000116761. Does this perturbation cause a significant change in ENSG00000116761 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF326 and then measure expression of CTH. Does this perturbation cause a significant change in CTH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2574 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UFM1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2475 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SOCS1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1906 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1674 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2329 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1759 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of YIPF5, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2527 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and ENSG00000135842 expression is measured. Determine whether ENSG00000135842 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MARS is perturbed and FAM129A expression is measured. Determine whether FAM129A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1219 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000143333 expression is quantified. Does this perturbation result in a significant change in ENSG00000143333 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":452 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of ENSG00000135842 is measured. Does this perturbation cause a significant change in ENSG00000135842 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MARS is perturbed and the expression of FAM129A is measured. Does this perturbation cause a significant change in FAM129A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1210 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2278 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B4 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":719 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":75 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSD17B12 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":948 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1465 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":410 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ENSG00000158869. Does perturbing TMEM167A lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of FCER1G. Does perturbing TMEM167A lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2351 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of ENSG00000127125. Does perturbing SRP68 lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP68 and examine the expression of PPCS. Does perturbing SRP68 lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1991 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF326 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2565 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ENSG00000117318 expression is measured. Determine whether ENSG00000117318 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPB1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":309 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":553 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":679 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":793 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":688 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM44 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2250 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61G and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1718 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":504 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC39A7 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1850 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000162664 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162664 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ZNF326 expression. Decide whether this perturbation leads to a significant alteration in ZNF326 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2558 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1915 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI2 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2406 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1006 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":789 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":436 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":875 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000244038 expression is measured. Determine whether ENSG00000244038 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and DDOST expression is measured. Determine whether DDOST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":599 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ENSG00000117318 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPB1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":307 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1440 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPR is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2042 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of ENSG00000016490. Does perturbing UFM1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFM1 and examine the expression of CLCA1. Does perturbing UFM1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2481 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":942 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000143333 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143333 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1013 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of ENSG00000135837. Does this perturbation cause a significant change in ENSG00000135837 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to XRN1 and then measure expression of CEP350. Does this perturbation cause a significant change in CEP350 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2514 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1403 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1523 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2262 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1670 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2323 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DERL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":559 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KCTD16 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1160 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2150 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PPWD1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1445 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PDIA6 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1413 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000188290 is measured. Determine whether ENSG00000188290 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of HES4 is measured. Determine whether HES4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1236 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARHGAP22 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":70 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1119 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2283 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OST4 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1358 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000169442. Does perturbing HSD17B12 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of CD52. Does perturbing HSD17B12 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":931 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of ENSG00000169442. Does perturbing TMED2 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED2 and examine the expression of CD52. Does perturbing TMED2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2311 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1918 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STT3A and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2104 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC39A7, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1837 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000198771 expression is measured. Determine whether ENSG00000198771 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1319 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRPL39 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1285 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1572 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":210 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":924 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BHLHE40 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":170 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SCYL1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1622 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":909 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FARSB is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":750 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of ENSG00000092621. Does perturbing AARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AARS and examine the expression of PHGDH. Does perturbing AARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2107 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000197989. Does perturbing MRPL39 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of SNHG12. Does perturbing MRPL39 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1271 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61A1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1655 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2004 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":652 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1943 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PDIA6 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1412 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2479 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GBF1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":813 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":626 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and ENSG00000163191 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163191 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which QARS is perturbed and S100A11 expression is observed. Does this perturbation lead to a significant difference in S100A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1553 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1824 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2022 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMM50 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1582 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1017 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":157 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NEDD8 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1324 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2003 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSD17B12 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":944 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1382 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61A1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1659 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2110 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2394 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPB1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":325 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2054 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMEM167A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2358 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2109 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MANF is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1172 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AMIGO3 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":53 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":826 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1166 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1996 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61G is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1739 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1450 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2235 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000158869. Does perturbing GBF1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of FCER1G. Does perturbing GBF1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":811 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DAD1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":392 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":168 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":530 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000198771 is measured. Determine whether ENSG00000198771 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MTHFD1 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1316 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FECH is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":803 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of ENSG00000142669. Does perturbing COPB1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COPB1 and examine the expression of SH3BGRL3. Does perturbing COPB1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":321 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of ENSG00000235169 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MTHFD1, does the expression profile of SMIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1297 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000116761 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116761 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and CTH expression is observed. Does this perturbation lead to a significant difference in CTH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":373 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IDH3A is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1103 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GMPPB, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":847 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of ENSG00000197989. Does perturbing ARHGAP22 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SNHG12. Does perturbing ARHGAP22 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":81 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1203 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2477 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000159352. Does perturbing PSMD4 lead to a significant change in ENSG00000159352 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of PSMD4. Does perturbing PSMD4 lead to a significant change in PSMD4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1471 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1286 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":650 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":678 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1693 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SOCS1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1908 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLMO2, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1877 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PDIA6 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1415 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of ENSG00000177954. Does perturbing AMIGO3 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AMIGO3 and examine the expression of RPS27. Does perturbing AMIGO3 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":31 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COPZ1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":335 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000188672. Does perturbing SLC39A7 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of RHCE. Does perturbing SLC39A7 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1851 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STT3A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2127 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2314 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FECH and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":808 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1810 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1537 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DERL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":558 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TARS and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2184 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000177954. Does perturbing SRP72 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of RPS27. Does perturbing SRP72 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2031 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000016490. Does perturbing YIPF5 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of CLCA1. Does perturbing YIPF5 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2521 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":425 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1954 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":518 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":824 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000198756. Does this perturbation cause a significant change in ENSG00000198756 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":234 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2274 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2055 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000117289. Does perturbing MARS lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of TXNIP. Does perturbing MARS lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1201 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS3 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1973 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1100 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2560 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CCND3 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":255 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":94 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2026 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to P4HB and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1404 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFM1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2466 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1023 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM23 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2239 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GNPNAT1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":894 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61G is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1712 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC63 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1748 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":960 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of ENSG00000092621. Does perturbing QARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb QARS and examine the expression of PHGDH. Does perturbing QARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1531 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of ENSG00000016490. Does perturbing EIF2B4 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of CLCA1. Does perturbing EIF2B4 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":701 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":980 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":46 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2524 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000227533 expression is quantified. Does this perturbation result in a significant change in ENSG00000227533 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":202 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TTI1 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2376 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000197989. Does perturbing DERL2 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of SNHG12. Does perturbing DERL2 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":561 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":640 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2294 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1262 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC63 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1765 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor ENSG00000127125 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127125 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SRP68 and monitor PPCS expression. Decide whether this perturbation leads to a significant alteration in PPCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1998 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2186 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSPA5 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":962 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PSMD4 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1482 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":439 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":400 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":30 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000143226. Does perturbing SARS lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of FCGR2A. Does perturbing SARS lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1611 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1859 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SCYL1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1620 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MARS and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1204 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AMIGO3 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":54 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor ENSG00000244038 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000244038 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor DDOST expression. Decide whether this perturbation leads to a significant alteration in DDOST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":978 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B3, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":687 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":756 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":423 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":957 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":40 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CAD and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":194 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of ENSG00000188672. Does perturbing PSMD4 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PSMD4 and examine the expression of RHCE. Does perturbing PSMD4 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1481 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2256 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1930 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1715 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1500 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HYOU1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1045 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1820 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1014 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1046 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NEDD8 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1340 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of ENSG00000197989. Does perturbing GMPPB lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GMPPB and examine the expression of SNHG12. Does perturbing GMPPB lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":851 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTDSS1 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1513 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDOST is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":486 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UFL1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2450 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1962 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATP5B is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":140 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CARS is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":213 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2033 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor ENSG00000070785 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070785 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B3 and monitor EIF2B3 expression. Decide whether this perturbation leads to a significant alteration in EIF2B3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":668 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000016490. Does perturbing FARSB lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of CLCA1. Does perturbing FARSB lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":761 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TTI1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2390 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IDH3A is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1102 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1305 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM44 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2253 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DARS is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":449 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1328 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FECH is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":809 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1049 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":525 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA9, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1007 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2389 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PPWD1 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1466 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA9 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":996 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2085 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1458 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1542 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of ENSG00000197989. Does perturbing PDIA6 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PDIA6 and examine the expression of SNHG12. Does perturbing PDIA6 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1411 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPCS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1925 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":414 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ENSG00000162511 expression is measured. Determine whether ENSG00000162511 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and LAPTM5 expression is measured. Determine whether LAPTM5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":119 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC39A7 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1838 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSD17B12 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":953 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1352 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000197989. Does perturbing ATP5B lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of SNHG12. Does perturbing ATP5B lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":131 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000169442. Does perturbing PPWD1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of CD52. Does perturbing PPWD1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1441 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1109 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SYVN1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2132 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TARS is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2183 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2014 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTDSS1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1509 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000135842 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135842 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and FAM129A expression is observed. Does this perturbation lead to a significant difference in FAM129A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1213 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TIMM44, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2267 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CHERP and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":284 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":13 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":804 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor ENSG00000143333 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143333 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF326 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2568 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1256 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1882 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NEDD8, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1337 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":907 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1934 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of ENSG00000143333. Does perturbing EIF2S1 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2S1 and examine the expression of RGS16. Does perturbing EIF2S1 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":741 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED2 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2338 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2180 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of ENSG00000130766 is measured. Does this perturbation cause a significant change in ENSG00000130766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CREB1 is perturbed and the expression of SESN2 is measured. Does this perturbation cause a significant change in SESN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":380 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1399 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and ENSG00000198492 expression is measured. Determine whether ENSG00000198492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PDIA6 is perturbed and YTHDF2 expression is measured. Determine whether YTHDF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1439 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRPL39 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1269 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1142 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2S1 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":724 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTDSS1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1508 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":983 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2192 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FARSB is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":776 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2134 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ENSG00000162664 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ZNF326 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2557 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and ENSG00000159352 expression is measured. Determine whether ENSG00000159352 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PSMD4 is perturbed and PSMD4 expression is measured. Determine whether PSMD4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1479 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFM1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2474 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":478 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPZ1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":354 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":852 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2438 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000070785 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in EIF2B3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":665 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMEM167A is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2343 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, P4HB is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1402 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1607 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DAD1 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":390 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS3 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1972 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC61B is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1692 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":332 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000197989. Does perturbing SRP72 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of SNHG12. Does perturbing SRP72 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2011 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRGBP is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1242 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":484 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and ENSG00000235169 expression is observed. Does this perturbation lead to a significant difference in ENSG00000235169 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PSMD4 is perturbed and SMIM1 expression is observed. Does this perturbation lead to a significant difference in SMIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1493 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1484 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TARS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2189 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SRP68 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2000 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEL1L is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1792 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPR is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2065 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CHERP is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":286 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PPWD1 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1460 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":7 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1099 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2342 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000177954. Does perturbing MRPL39 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of RPS27. Does perturbing MRPL39 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1281 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of ENSG00000197989. Does perturbing SEC61B lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of SNHG12. Does perturbing SEC61B lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1681 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor ENSG00000162511 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162511 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ASCC3 and monitor LAPTM5 expression. Decide whether this perturbation leads to a significant alteration in LAPTM5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":118 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CCND3 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":263 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":500 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000092621. Does perturbing CARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of PHGDH. Does perturbing CARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":211 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":28 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TTI1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2387 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor ENSG00000116761 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116761 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CREB1 and monitor CTH expression. Decide whether this perturbation leads to a significant alteration in CTH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":378 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of ENSG00000159352 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PSMD4, does the expression profile of PSMD4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1477 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of ENSG00000198771. Does perturbing CHERP lead to a significant change in ENSG00000198771 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CHERP and examine the expression of RCSD1. Does perturbing CHERP lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":291 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which P4HB is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1383 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NEDD8 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1342 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP72 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2015 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SRP68 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1989 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of ENSG00000244038. Does this perturbation cause a significant change in ENSG00000244038 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DHDDS and then measure expression of DDOST. Does this perturbation cause a significant change in DDOST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":594 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HYOU1, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1047 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CCND3, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":257 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDRGK1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":520 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1228 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRGBP and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1258 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2535 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":246 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":615 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STT3A and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2128 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of ENSG00000244038 is measured. Determine whether ENSG00000244038 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DHDDS is perturbed and the expression of DDOST is measured. Determine whether DDOST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":596 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CREB1 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":366 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS3 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1978 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DAD1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":394 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000162511 is measured. Determine whether ENSG00000162511 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61A1 is perturbed and the expression of LAPTM5 is measured. Determine whether LAPTM5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1666 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1372 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HYOU1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1020 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DNAJC19 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":610 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS3 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1956 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FARSB is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":753 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000169442. Does perturbing NEDD8 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of CD52. Does perturbing NEDD8 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1331 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":618 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2S1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":722 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM23 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2246 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, XRN1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2500 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1742 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SCYL1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1645 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DHDDS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":585 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of ENSG00000162511 is measured. Does this perturbation cause a significant change in ENSG00000162511 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61A1 is perturbed and the expression of LAPTM5 is measured. Does this perturbation cause a significant change in LAPTM5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1660 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1139 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in ENSG00000188290 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MRGBP is associated with a significant change in HES4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1235 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":55 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA5 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":963 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER3IP1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1120 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":82 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":605 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2129 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1462 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FECH, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":807 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000130766. Does this perturbation cause a significant change in ENSG00000130766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of SESN2. Does this perturbation cause a significant change in SESN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":174 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PPWD1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1452 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2245 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1104 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in ENSG00000130766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CREB1 is associated with a significant change in SESN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":385 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CARS and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":214 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2538 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1174 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B3 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":675 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2315 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CCND3 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":264 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TTI2 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2425 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MRPL39 is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1280 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRPR and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2044 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":52 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000227533 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":205 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC39A7 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1844 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1076 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of ENSG00000143333. Does perturbing EIF2B3 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B3 and examine the expression of RGS16. Does perturbing EIF2B3 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":681 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in ENSG00000117289 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CAD is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":185 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":532 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of ENSG00000142669. Does perturbing ASCC3 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ASCC3 and examine the expression of SH3BGRL3. Does perturbing ASCC3 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":101 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":658 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IARS2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1066 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of ENSG00000142669. Does perturbing SLC39A7 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC39A7 and examine the expression of SH3BGRL3. Does perturbing SLC39A7 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1831 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTDSS1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1510 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000244038. Does perturbing DDOST lead to a significant change in ENSG00000244038 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of DDOST. Does perturbing DDOST lead to a significant change in DDOST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":481 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of ENSG00000159388 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COPZ1, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":347 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATP5B is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":123 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CAD is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":183 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, P4HB is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1386 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2B4, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":697 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of ENSG00000163191 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of QARS, does the expression profile of S100A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1557 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED10 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2296 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of ENSG00000143226 is measured. Determine whether ENSG00000143226 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLMO2 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1876 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLMO2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1883 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61B is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1683 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CHERP is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":285 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61G is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1726 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":252 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2543 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000142669. Does perturbing SPCS3 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of SH3BGRL3. Does perturbing SPCS3 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1971 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1985 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of ENSG00000127125 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GNPNAT1, does the expression profile of PPCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":887 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of ENSG00000177606. Does perturbing MARS lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MARS and examine the expression of JUN. Does perturbing MARS lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1221 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1323 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SARS is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1610 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SEC63 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1752 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1846 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb YIPF5 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2528 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP72 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2024 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1949 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEL1L and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1788 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":227 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NEDD8 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1346 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":405 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2005 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":778 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BHLHE40 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":169 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1717 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRGBP is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1246 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC35B1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1803 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IARS2, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1057 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1263 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DNAJC19 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":625 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DHDDS is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":573 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000016490. Does perturbing DHDDS lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of CLCA1. Does perturbing DHDDS lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":571 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM44 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2272 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPZ1 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":342 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":97 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2243 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":259 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of ENSG00000188290 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MRGBP, does the expression profile of HES4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1237 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DAD1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":397 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":755 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2200 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000143333 is measured. Determine whether ENSG00000143333 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":456 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1700 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000177954 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of RPS27 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":477 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1942 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":883 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1143 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDOST is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":490 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":638 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of ENSG00000158869. Does perturbing ATP5B lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATP5B and examine the expression of FCER1G. Does perturbing ATP5B lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":141 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BHLHE40 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":158 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and ENSG00000198771 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198771 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CHERP is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":293 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor ENSG00000235169 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000235169 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PSMD4 and monitor SMIM1 expression. Decide whether this perturbation leads to a significant alteration in SMIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1498 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HARS is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":919 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2382 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and ENSG00000177954 expression is measured. Determine whether ENSG00000177954 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDIT3 is perturbed and RPS27 expression is measured. Determine whether RPS27 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":479 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000197989. Does perturbing TMED10 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of SNHG12. Does perturbing TMED10 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2281 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of ENSG00000143333. Does this perturbation cause a significant change in ENSG00000143333 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BHLHE40 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":164 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DDOST is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":493 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STT3A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2120 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of ENSG00000169442. Does perturbing SPCS3 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPCS3 and examine the expression of CD52. Does perturbing SPCS3 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1951 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000135837 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of CEP350 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2517 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER3IP1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1118 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA9 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":994 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of ENSG00000158869. Does perturbing IER3IP1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER3IP1 and examine the expression of FCER1G. Does perturbing IER3IP1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1121 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SCYL1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1647 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1948 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BHLHE40 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":156 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GMPPB is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":863 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000127125 expression is observed. Does this perturbation lead to a significant difference in ENSG00000127125 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and PPCS expression is observed. Does this perturbation lead to a significant difference in PPCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1193 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":642 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1024 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IARS2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1078 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DNAJC19 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":628 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMEM167A is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2362 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000016490. Does perturbing TMED10 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of CLCA1. Does perturbing TMED10 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2301 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GNPNAT1 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":893 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of ENSG00000198492. Does this perturbation cause a significant change in ENSG00000198492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SYVN1 and then measure expression of YTHDF2. Does this perturbation cause a significant change in YTHDF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2144 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1300 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDRGK1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":538 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000169442. Does perturbing TTI1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of CD52. Does perturbing TTI1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2381 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CCND3 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":269 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of ENSG00000163386. Does perturbing XRN1 lead to a significant change in ENSG00000163386 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of NBPF10. Does perturbing XRN1 lead to a significant change in NBPF10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2491 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1623 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of ENSG00000197989. Does perturbing PTDSS1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTDSS1 and examine the expression of SNHG12. Does perturbing PTDSS1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1501 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1162 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":430 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1186 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COPB1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":320 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":800 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1832 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DARS is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":446 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OST4 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1362 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of ENSG00000169442. Does perturbing P4HB lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb P4HB and examine the expression of CD52. Does perturbing P4HB lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1381 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TIMM23 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2233 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMEM167A is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2349 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GMPPB is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":865 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPCS2 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1939 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM23 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2248 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of ENSG00000235169 is measured. Does this perturbation cause a significant change in ENSG00000235169 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MTHFD1 is perturbed and the expression of SMIM1 is measured. Does this perturbation cause a significant change in SMIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1290 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B4 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":718 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000163191 expression is quantified. Does this perturbation result in a significant change in ENSG00000163191 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and S100A11 expression is quantified. Does this perturbation result in a significant change in S100A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1552 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRPL39 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1264 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of ENSG00000158869. Does perturbing DHDDS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DHDDS and examine the expression of FCER1G. Does perturbing DHDDS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":581 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDIT3 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":472 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":645 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AARS is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":23 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000016490. Does perturbing DAD1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of CLCA1. Does perturbing DAD1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":401 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000117289 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":187 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of ENSG00000162511 is measured. Does this perturbation cause a significant change in ENSG00000162511 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ASCC3 is perturbed and the expression of LAPTM5 is measured. Does this perturbation cause a significant change in LAPTM5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":110 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NEDD8 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1349 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DDRGK1 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":519 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and ENSG00000130766 expression is quantified. Does this perturbation result in a significant change in ENSG00000130766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BHLHE40 is perturbed and SESN2 expression is quantified. Does this perturbation result in a significant change in SESN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":172 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000143333 is measured. Does this perturbation cause a significant change in ENSG00000143333 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DDIT3 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":450 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":715 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GBF1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":814 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in ENSG00000162511 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ASCC3 is associated with a significant change in LAPTM5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":115 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TIMM23 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2225 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of ENSG00000143226. Does perturbing SAMM50 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMM50 and examine the expression of FCGR2A. Does perturbing SAMM50 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1581 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000143226 is measured. Does this perturbation cause a significant change in ENSG00000143226 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSD17B12 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":950 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TELO2 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2206 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1697 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and ENSG00000135837 expression is quantified. Does this perturbation result in a significant change in ENSG00000135837 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, XRN1 is perturbed and CEP350 expression is quantified. Does this perturbation result in a significant change in CEP350 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2512 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000116761 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of CTH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":377 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which YIPF5 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2523 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SCYL1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1636 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GMPPB is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":842 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRPRB is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2076 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B2 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":635 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1208 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of YIPF5 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2525 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of ENSG00000188672. Does perturbing TELO2 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TELO2 and examine the expression of RHCE. Does perturbing TELO2 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2211 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2347 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and ENSG00000188290 expression is measured. Determine whether ENSG00000188290 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MRGBP is perturbed and HES4 expression is measured. Determine whether HES4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1239 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PDIA6 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1414 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSD17B12, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":937 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP72 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2032 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OST4 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1369 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1705 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDIT3, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":467 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OST4 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1355 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP68 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1983 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb XRN1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2508 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ENSG00000163191. Does this perturbation cause a significant change in ENSG00000163191 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of S100A11. Does this perturbation cause a significant change in S100A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1554 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000143333 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":745 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of ENSG00000177954. Does perturbing SOCS1 lead to a significant change in ENSG00000177954 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SOCS1 and examine the expression of RPS27. Does perturbing SOCS1 lead to a significant change in RPS27 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1891 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and ENSG00000143333 expression is measured. Determine whether ENSG00000143333 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2B3 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":689 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":149 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PPWD1 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1468 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IARS2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1074 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED2 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2324 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KCTD16 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1164 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of ENSG00000198492 is measured. Determine whether ENSG00000198492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PDIA6 is perturbed and the expression of YTHDF2 is measured. Determine whether YTHDF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1436 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED10 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2293 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MRPL39 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1282 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRP68 is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1995 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DNAJC19 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":606 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FARSB and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":774 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MRGBP and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1244 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ENSG00000143226 expression is measured. Determine whether ENSG00000143226 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1589 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HSPA5, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":967 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000016490. Does perturbing SCYL1 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of CLCA1. Does perturbing SCYL1 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1641 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARHGAP22 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":72 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GNPNAT1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":895 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and ENSG00000116761 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116761 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF326 is perturbed and CTH expression is observed. Does this perturbation lead to a significant difference in CTH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2573 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000127125 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in PPCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2075 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFM1 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2478 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STT3A is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2126 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TELO2 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2210 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DDRGK1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":517 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DARS and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":428 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FARSB is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":759 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2312 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B2 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":632 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPCS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1926 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61B is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1685 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COPB1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":323 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC39A7 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1853 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of ENSG00000158869. Does perturbing DDRGK1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDRGK1 and examine the expression of FCER1G. Does perturbing DDRGK1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":521 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AMIGO3 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":36 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2B2 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":648 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPCS2 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1932 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of ENSG00000169442. Does perturbing TMED10 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMED10 and examine the expression of CD52. Does perturbing TMED10 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2291 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HYOU1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1028 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TIMM23 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2232 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS3, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1977 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMM50 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1565 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HSD17B12 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":952 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPCS2 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1933 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of ENSG00000127125. Does perturbing SRPRB lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPRB and examine the expression of PPCS. Does perturbing SRPRB lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2071 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NEDD8 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1345 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and ENSG00000188672 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188672 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TELO2 is perturbed and RHCE expression is observed. Does this perturbation lead to a significant difference in RHCE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2213 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFL1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2453 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of ENSG00000130766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CREB1, does the expression profile of SESN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":387 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2434 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000159352. Does this perturbation cause a significant change in ENSG00000159352 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of PSMD4. Does this perturbation cause a significant change in PSMD4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1474 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and ENSG00000177954 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177954 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MRPL39 is perturbed and RPS27 expression is observed. Does this perturbation lead to a significant difference in RPS27 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1283 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":547 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IDH3A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1084 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2S1 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":725 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, P4HB is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1389 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ENSG00000117318 is measured. Determine whether ENSG00000117318 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPB1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":306 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":535 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000016490. Does perturbing TIMM44 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of CLCA1. Does perturbing TIMM44 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2271 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and ENSG00000116761 expression is quantified. Does this perturbation result in a significant change in ENSG00000116761 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CREB1 is perturbed and CTH expression is quantified. Does this perturbation result in a significant change in CTH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":372 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DARS is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":445 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRP72 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2013 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1905 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and ENSG00000117289 expression is measured. Determine whether ENSG00000117289 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IDH3A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1089 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":634 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":927 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, XRN1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2506 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UFL1 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2448 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CCND3 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":242 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000198771 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198771 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":298 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COPZ1 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":346 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of ENSG00000188672 is measured. Does this perturbation cause a significant change in ENSG00000188672 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CCND3 is perturbed and the expression of RHCE is measured. Does this perturbation cause a significant change in RHCE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":260 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ASCC3, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":107 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":792 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DHDDS is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":589 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AMIGO3 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":48 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM44 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2264 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATP5B and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":144 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":475 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of ENSG00000016490. Does perturbing DDOST lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DDOST and examine the expression of CLCA1. Does perturbing DDOST lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":501 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FECH is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":782 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":706 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRPRB is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2072 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of ENSG00000188290. Does perturbing MRGBP lead to a significant change in ENSG00000188290 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRGBP and examine the expression of HES4. Does perturbing MRGBP lead to a significant change in HES4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1231 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMED2 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2333 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1522 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of ENSG00000142669. Does perturbing NEDD8 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NEDD8 and examine the expression of SH3BGRL3. Does perturbing NEDD8 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1341 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1992 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MARS is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1223 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FECH is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":780 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B2 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":630 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED10 is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2280 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of ENSG00000143226. Does perturbing HSD17B12 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSD17B12 and examine the expression of FCGR2A. Does perturbing HSD17B12 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":951 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":796 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SEC61B and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1688 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA9 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1008 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1733 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in ENSG00000235169 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PSMD4 is associated with a significant change in SMIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1495 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SOCS1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1913 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":542 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":815 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DERL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":557 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ENSG00000162664 expression is quantified. Does this perturbation result in a significant change in ENSG00000162664 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF326 is perturbed and ZNF326 expression is quantified. Does this perturbation result in a significant change in ZNF326 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2552 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":338 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ASCC3 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":104 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1618 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and ENSG00000198756 expression is measured. Determine whether ENSG00000198756 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IARS2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1069 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2339 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DNAJC19 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":603 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000235169 is measured. Does this perturbation cause a significant change in ENSG00000235169 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PSMD4 is perturbed and the expression of SMIM1 is measured. Does this perturbation cause a significant change in SMIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1490 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER3IP1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1112 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of ENSG00000158869. Does perturbing UFL1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UFL1 and examine the expression of FCER1G. Does perturbing UFL1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2431 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMED2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2319 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLMO2 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1872 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B4 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":712 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of ENSG00000092621. Does perturbing FARSB lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FARSB and examine the expression of PHGDH. Does perturbing FARSB lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":751 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":705 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFM1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2489 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2168 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of ENSG00000198756 is measured. Determine whether ENSG00000198756 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2S1 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":736 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CAD and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":188 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NEDD8 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1343 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of ENSG00000235169. Does this perturbation cause a significant change in ENSG00000235169 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PSMD4 and then measure expression of SMIM1. Does this perturbation cause a significant change in SMIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1494 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GBF1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":832 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARHGAP22 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":65 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KCTD16 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1163 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AMIGO3 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":45 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AARS is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":16 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of ENSG00000158869. Does perturbing DERL2 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DERL2 and examine the expression of FCER1G. Does perturbing DERL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":551 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of XRN1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2507 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2214 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, YIPF5 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2526 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of ENSG00000197989 is measured. Does this perturbation cause a significant change in ENSG00000197989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61B is perturbed and the expression of SNHG12 is measured. Does this perturbation cause a significant change in SNHG12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1680 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC35B1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1809 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER3IP1 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1129 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in ENSG00000198771 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MTHFD1 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1315 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EIF2S1 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":729 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP72 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2016 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of ENSG00000197989. Does perturbing GBF1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GBF1 and examine the expression of SNHG12. Does perturbing GBF1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":821 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KCTD16 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1156 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DERL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":552 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and ENSG00000198756 expression is quantified. Does this perturbation result in a significant change in ENSG00000198756 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IARS2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1062 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLMO2 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1868 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1288 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMEM167A is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2360 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1628 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1514 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DERL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":556 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NEDD8 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1348 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FECH and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":794 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and ENSG00000158869 expression is measured. Determine whether ENSG00000158869 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AMIGO3 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":49 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2167 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MRPL39 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1266 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSPA5 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":986 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61B, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1707 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2384 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000143226 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143226 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2268 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1504 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CCND3 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":256 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2103 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MARS is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1225 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UFL1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2446 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1928 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HARS and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":908 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of ENSG00000227533 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CAD, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":207 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IDH3A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1086 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000162511. Does this perturbation cause a significant change in ENSG00000162511 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of LAPTM5. Does this perturbation cause a significant change in LAPTM5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1664 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of ENSG00000143226. Does perturbing TIMM44 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM44 and examine the expression of FCGR2A. Does perturbing TIMM44 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2261 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of QARS is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1545 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor ENSG00000130766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDIT3 and monitor SESN2 expression. Decide whether this perturbation leads to a significant alteration in SESN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":468 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of ENSG00000197989. Does perturbing YIPF5 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb YIPF5 and examine the expression of SNHG12. Does perturbing YIPF5 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2531 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER3IP1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1123 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COPZ1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":339 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MANF and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1178 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SOCS1 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1910 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of ENSG00000016490 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFM1, does the expression profile of CLCA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2487 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TARS is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2166 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS3 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1974 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MTHFD1 and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1308 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMED10 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2284 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HYOU1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1032 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FECH is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":786 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":727 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":32 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DDIT3 is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":476 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of ENSG00000159352 is measured. Determine whether ENSG00000159352 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PSMD4 is perturbed and the expression of PSMD4 is measured. Determine whether PSMD4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1476 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SRPR, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2047 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B4 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":704 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":902 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IARS2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1075 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EIF2B3 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":674 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMEM167A, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2357 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HSPA5 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":984 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and ENSG00000127125 expression is measured. Determine whether ENSG00000127125 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MANF is perturbed and PPCS expression is measured. Determine whether PPCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1199 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DARS is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":443 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AARS and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":24 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and ENSG00000143226 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143226 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2B4 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":713 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1706 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UFL1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2449 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of ENSG00000169442. Does perturbing KCTD16 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KCTD16 and examine the expression of CD52. Does perturbing KCTD16 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1141 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2392 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor ENSG00000177954 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177954 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GMPPB and monitor RPS27 expression. Decide whether this perturbation leads to a significant alteration in RPS27 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":848 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEC61G is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1730 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor ENSG00000135842 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135842 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MARS and monitor FAM129A expression. Decide whether this perturbation leads to a significant alteration in FAM129A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1218 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TIMM44 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2258 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DNAJC19 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":614 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEL1L is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1776 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1003 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPCS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1920 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of ENSG00000163191 is measured. Determine whether ENSG00000163191 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, QARS is perturbed and the expression of S100A11 is measured. Determine whether S100A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1556 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GBF1 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":816 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SEC61G, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1727 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HARS is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":910 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SCYL1 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1633 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SEC61G is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1725 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of ENSG00000143226. Does this perturbation cause a significant change in ENSG00000143226 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMM50 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1584 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KCTD16 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1145 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ENSG00000117318 expression is quantified. Does this perturbation result in a significant change in ENSG00000117318 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COPB1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":302 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATP5B is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":139 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UFL1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2457 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of ENSG00000092621. Does perturbing DARS lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DARS and examine the expression of PHGDH. Does perturbing DARS lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":431 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HSPA9 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1005 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of ENSG00000198771. Does perturbing MTHFD1 lead to a significant change in ENSG00000198771 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MTHFD1 and examine the expression of RCSD1. Does perturbing MTHFD1 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1311 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPCS2 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1944 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of ENSG00000177954 is measured. Determine whether ENSG00000177954 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GMPPB is perturbed and the expression of RPS27 is measured. Determine whether RPS27 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":846 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of ENSG00000158869. Does perturbing MRPL39 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MRPL39 and examine the expression of FCER1G. Does perturbing MRPL39 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1261 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MTHFD1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1309 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor ENSG00000197989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KCTD16 and monitor SNHG12 expression. Decide whether this perturbation leads to a significant alteration in SNHG12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1158 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPCS2, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1937 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EIF2S1 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":723 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CHERP and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":288 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMED2 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2336 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of ENSG00000117289. Does this perturbation cause a significant change in ENSG00000117289 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MANF and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1184 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of ENSG00000158869. Does perturbing TARS lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TARS and examine the expression of FCER1G. Does perturbing TARS lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2181 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of P4HB is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1385 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of ENSG00000159388. Does perturbing PPWD1 lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PPWD1 and examine the expression of BTG2. Does perturbing PPWD1 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1461 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HYOU1 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1033 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AMIGO3 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":42 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EIF2B3 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":672 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IDH3A is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1090 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COPZ1 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":348 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMED10 and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2308 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KCTD16 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1152 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000016490. Does perturbing TIMM23 lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of CLCA1. Does perturbing TIMM23 lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2221 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMED10 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2285 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SRPR is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2063 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000117289. Does perturbing MANF lead to a significant change in ENSG00000117289 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of TXNIP. Does perturbing MANF lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1181 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor ENSG00000198756 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198756 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EIF2S1 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":738 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and ENSG00000117289 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117289 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MANF is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1183 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in ENSG00000198492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SRPRB is associated with a significant change in YTHDF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2095 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of ENSG00000188672. Does perturbing TTI1 lead to a significant change in ENSG00000188672 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI1 and examine the expression of RHCE. Does perturbing TTI1 lead to a significant change in RHCE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2371 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HSPA9 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":993 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and ENSG00000116761 expression is measured. Determine whether ENSG00000116761 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF326 is perturbed and CTH expression is measured. Determine whether CTH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2579 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of ENSG00000142669. Does perturbing TIMM23 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TIMM23 and examine the expression of SH3BGRL3. Does perturbing TIMM23 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2241 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of ENSG00000130766. Does perturbing CREB1 lead to a significant change in ENSG00000130766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CREB1 and examine the expression of SESN2. Does perturbing CREB1 lead to a significant change in SESN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":381 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2567 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDRGK1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":524 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":17 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPCS2 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1938 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TELO2 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2202 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and ENSG00000127125 expression is quantified. Does this perturbation result in a significant change in ENSG00000127125 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GNPNAT1 is perturbed and PPCS expression is quantified. Does this perturbation result in a significant change in PPCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":882 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1842 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SCYL1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1624 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, QARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1532 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SYVN1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2130 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":564 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC39A7 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1855 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OST4 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1366 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EIF2B4 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":695 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in ENSG00000143226 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FARSB is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":775 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EIF2B4 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":696 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of ENSG00000158869. Does perturbing SCYL1 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SCYL1 and examine the expression of FCER1G. Does perturbing SCYL1 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1631 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of ENSG00000198756. Does perturbing CARS lead to a significant change in ENSG00000198756 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CARS and examine the expression of COLGALT2. Does perturbing CARS lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":231 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER3IP1, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1127 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTDSS1 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1502 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000177954 expression is quantified. Does this perturbation result in a significant change in ENSG00000177954 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RPS27 expression is quantified. Does this perturbation result in a significant change in RPS27 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1892 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STT3A is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2113 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of ENSG00000127125. Does perturbing MANF lead to a significant change in ENSG00000127125 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MANF and examine the expression of PPCS. Does perturbing MANF lead to a significant change in PPCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1191 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of ENSG00000197989. Does perturbing SEC61G lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61G and examine the expression of SNHG12. Does perturbing SEC61G lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1721 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of ENSG00000016490. Does this perturbation cause a significant change in ENSG00000016490 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of CLCA1. Does this perturbation cause a significant change in CLCA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2224 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of ENSG00000197989. Does perturbing DAD1 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DAD1 and examine the expression of SNHG12. Does perturbing DAD1 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":391 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, XRN1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2509 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SOCS1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1902 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DAD1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":395 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SYVN1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2137 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of ENSG00000158869. Does perturbing SRP72 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRP72 and examine the expression of FCER1G. Does perturbing SRP72 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2021 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of ENSG00000197989. Does perturbing SEC63 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC63 and examine the expression of SNHG12. Does perturbing SEC63 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1761 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of ENSG00000197989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GBF1, does the expression profile of SNHG12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":827 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and ENSG00000117289 expression is quantified. Does this perturbation result in a significant change in ENSG00000117289 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CAD is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":182 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and ENSG00000130766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CREB1 is perturbed and SESN2 expression is observed. Does this perturbation lead to a significant difference in SESN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":383 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC61B is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1689 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of ENSG00000031698. Does perturbing SARS lead to a significant change in ENSG00000031698 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SARS and examine the expression of SARS. Does perturbing SARS lead to a significant change in SARS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1591 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SEC61A1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1654 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AMIGO3 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":50 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMED2 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2332 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDRGK1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":515 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of ENSG00000197989. Does perturbing SRPR lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SRPR and examine the expression of SNHG12. Does perturbing SRPR lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2041 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of ENSG00000016490 is measured. Does this perturbation cause a significant change in ENSG00000016490 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GBF1 is perturbed and the expression of CLCA1 is measured. Does this perturbation cause a significant change in CLCA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":830 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and ENSG00000016490 expression is quantified. Does this perturbation result in a significant change in ENSG00000016490 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, YIPF5 is perturbed and CLCA1 expression is quantified. Does this perturbation result in a significant change in CLCA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2522 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLMO2 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1864 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in ENSG00000177954 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SOCS1 is associated with a significant change in RPS27 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1895 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TIMM23 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2240 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of ENSG00000188672 is measured. Determine whether ENSG00000188672 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC39A7 is perturbed and the expression of RHCE is measured. Determine whether RHCE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1856 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CARS, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":217 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI1 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2372 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of ENSG00000092621. Does perturbing HSPA9 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of PHGDH. Does perturbing HSPA9 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":991 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC39A7 is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1852 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ENSG00000198756 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198756 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1063 } ]