[ { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and ENSG00000244038 expression is quantified. Does this perturbation result in a significant change in ENSG00000244038 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DHDDS is perturbed and DDOST expression is quantified. Does this perturbation result in a significant change in DDOST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":592 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC63 is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1763 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of ENSG00000092621. Does perturbing EIF2B4 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of PHGDH. Does perturbing EIF2B4 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":691 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TARS is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2162 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ENSG00000162664. Does perturbing ZNF326 lead to a significant change in ENSG00000162664 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF326 and examine the expression of ZNF326. Does perturbing ZNF326 lead to a significant change in ZNF326 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2551 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of ENSG00000143226. Does perturbing EIF2B4 lead to a significant change in ENSG00000143226 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EIF2B4 and examine the expression of FCGR2A. Does perturbing EIF2B4 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":711 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SEC63 is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1769 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HSPA5 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":968 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to QARS and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1544 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in ENSG00000130766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDIT3 is associated with a significant change in SESN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":465 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC39A7 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1849 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATP5B is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":125 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TELO2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2194 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and ENSG00000197989 expression is quantified. Does this perturbation result in a significant change in ENSG00000197989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TTI2 is perturbed and SNHG12 expression is quantified. Does this perturbation result in a significant change in SNHG12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2422 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb P4HB and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1388 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SEC61B is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1696 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of ENSG00000143333. Does perturbing HSPA9 lead to a significant change in ENSG00000143333 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HSPA9 and examine the expression of RGS16. Does perturbing HSPA9 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1011 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DERL2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":544 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EIF2S1, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":747 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in ENSG00000188672 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTDSS1 is associated with a significant change in RHCE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1515 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of ENSG00000143333 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BHLHE40, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":167 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of ENSG00000135837. Does perturbing XRN1 lead to a significant change in ENSG00000135837 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb XRN1 and examine the expression of CEP350. Does perturbing XRN1 lead to a significant change in CEP350 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2511 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GBF1 is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":825 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TARS is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2160 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and ENSG00000143226 expression is quantified. Does this perturbation result in a significant change in ENSG00000143226 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SARS is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1612 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of ENSG00000244038 is measured. Does this perturbation cause a significant change in ENSG00000244038 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HSPA5 is perturbed and the expression of DDOST is measured. Does this perturbation cause a significant change in DDOST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":970 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in ENSG00000197989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IDH3A is associated with a significant change in SNHG12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1105 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ASCC3 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":99 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor ENSG00000031698 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000031698 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SARS and monitor SARS expression. Decide whether this perturbation leads to a significant alteration in SARS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1598 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of ENSG00000158869. Does perturbing SEC61B lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SEC61B and examine the expression of FCER1G. Does perturbing SEC61B lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1701 }, { "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in ENSG00000016490 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DDOST is associated with a significant change in CLCA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":505 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to YIPF5 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2534 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TIMM44 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2276 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of ENSG00000127125. Does this perturbation cause a significant change in ENSG00000127125 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SRP68 and then measure expression of PPCS. Does this perturbation cause a significant change in PPCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1994 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMM50 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1579 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of ENSG00000143226 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AARS, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":27 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CAD is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":180 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of ENSG00000197989. Does this perturbation cause a significant change in ENSG00000197989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TTI2 and then measure expression of SNHG12. Does this perturbation cause a significant change in SNHG12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2424 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COPB1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":324 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARHGAP22, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":77 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor ENSG00000117289 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117289 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GNPNAT1 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":878 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and ENSG00000188672 expression is measured. Determine whether ENSG00000188672 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TTI1 is perturbed and RHCE expression is measured. Determine whether RHCE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2379 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of ENSG00000016490. Does perturbing TMEM167A lead to a significant change in ENSG00000016490 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMEM167A and examine the expression of CLCA1. Does perturbing TMEM167A lead to a significant change in CLCA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2341 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of ENSG00000117289 is measured. Determine whether ENSG00000117289 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CAD is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":186 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and ENSG00000197989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SEC61G is perturbed and SNHG12 expression is observed. Does this perturbation lead to a significant difference in SNHG12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1723 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of ENSG00000142669. Does perturbing ARHGAP22 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARHGAP22 and examine the expression of SH3BGRL3. Does perturbing ARHGAP22 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":61 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of ENSG00000177954. Does this perturbation cause a significant change in ENSG00000177954 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HYOU1 and then measure expression of RPS27. Does this perturbation cause a significant change in RPS27 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1044 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GMPPB is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":859 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TIMM23 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2244 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of ENSG00000116761 is measured. Does this perturbation cause a significant change in ENSG00000116761 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF326 is perturbed and the expression of CTH is measured. Does this perturbation cause a significant change in CTH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2570 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of ENSG00000188672. Does this perturbation cause a significant change in ENSG00000188672 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DDOST and then measure expression of RHCE. Does this perturbation cause a significant change in RHCE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":494 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and ENSG00000016490 expression is observed. Does this perturbation lead to a significant difference in ENSG00000016490 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UFM1 is perturbed and CLCA1 expression is observed. Does this perturbation lead to a significant difference in CLCA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2483 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of ENSG00000197989 is measured. Determine whether ENSG00000197989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SRP68 is perturbed and the expression of SNHG12 is measured. Determine whether SNHG12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2006 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTDSS1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1524 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SRP68 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1982 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of ENSG00000016490 is measured. Determine whether ENSG00000016490 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HYOU1 is perturbed and the expression of CLCA1 is measured. Determine whether CLCA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1026 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TELO2 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2209 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMED2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2310 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ENSG00000177954 is measured. Does this perturbation cause a significant change in ENSG00000177954 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"No", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of RPS27 is measured. Does this perturbation cause a significant change in RPS27 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1780 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of P4HB, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1397 }, { "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of ENSG00000116761 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF326, does the expression profile of CTH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2577 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SCYL1 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1638 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of ENSG00000117289 is measured. Does this perturbation cause a significant change in ENSG00000117289 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SEL1L is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1770 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC35B1 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1814 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MRPL39 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1268 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HYOU1 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1029 }, { "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of ENSG00000197989. Does perturbing TTI2 lead to a significant change in ENSG00000197989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TTI2 and examine the expression of SNHG12. Does perturbing TTI2 lead to a significant change in SNHG12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2421 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor ENSG00000188672 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188672 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DDOST and monitor RHCE expression. Decide whether this perturbation leads to a significant alteration in RHCE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":498 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDRGK1 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":522 }, { "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and ENSG00000188672 expression is quantified. Does this perturbation result in a significant change in ENSG00000188672 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DDOST is perturbed and RHCE expression is quantified. Does this perturbation result in a significant change in RHCE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.", "_id":492 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DERL2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":543 }, { "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IARS2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1073 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of ENSG00000070785 is measured. Does this perturbation cause a significant change in ENSG00000070785 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EIF2B3 is perturbed and the expression of EIF2B3 is measured. Does this perturbation cause a significant change in EIF2B3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":660 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of ENSG00000127125 is measured. Determine whether ENSG00000127125 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MANF is perturbed and the expression of PPCS is measured. Determine whether PPCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1196 }, { "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UFL1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2454 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and ENSG00000197989 expression is measured. Determine whether ENSG00000197989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STT3A is perturbed and SNHG12 expression is measured. Determine whether SNHG12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2119 }, { "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HSD17B12 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":936 }, { "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC35B1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":1800 }, { "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and ENSG00000016490 expression is measured. Determine whether ENSG00000016490 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TIMM44 is perturbed and CLCA1 expression is measured. Determine whether CLCA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.", "_id":2279 }, { "question":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor ENSG00000016490 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000016490 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "answer":"Yes", "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FARSB and monitor CLCA1 expression. Decide whether this perturbation leads to a significant alteration in CLCA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.", "_id":768 } ]